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@@ -110,6 +110,21 @@ Enzymes catalyzing more than one reaction appear in multiple enzyme-reaction pai
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  <sup>[1]|</sup> We excluded sequences with %identities ≥ 70% and pLDDTs < 60%.
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  - **PGP pipeline** [(see GitHub)](https://github.com/hefeda/PGP)
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  | Method | Natural | Generated |
 
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  <sup>[1]|</sup> We excluded sequences with %identities ≥ 70% and pLDDTs < 60%.
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+ - **Functional classification**
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+ | Method | [ProteInfer](https://google-research.github.io/proteinfer/) | ProteInfer | [CLEAN](https://www.science.org/doi/10.1126/science.adf2465) | CLEAN |
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+ | Method | Natural | Generated | Natural | Generated |
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+ | :--- | :----: | ---: |
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+ | **EC: Level 1** | 81 % | 80 % | 80 % | 79 % |
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+ | **EC: Level 2** | 78 % | 77 % | 79 % | 78 % |
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+ | **EC: Level 3** | 76 % | 75 % | 78 % | 77 % |
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+ | **EC: Level 4** | 62 % | 58 % | 70 % | 65 % |
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+ | ** No EC predicted ** | 10 % | 7 % | 0 % | 0 % |
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+ | ** GO-Terms ** | | 41 % | 39 % | - | - |
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+ | ** No GO predicted** | 1 % | 1 % | - | - |
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  - **PGP pipeline** [(see GitHub)](https://github.com/hefeda/PGP)
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  | Method | Natural | Generated |