data: # TODO: Update this path for your HPC cluster, e.g.: # root: "/scratch/$USER/immunogold_data/Gold Particle Labelling" root: "/Users/mpcr/Downloads/Max Planck Data/Gold Particle Labelling" analyzed_dir: "analyzed synapses" test_dir: "labeled replica - Test Data from Synapses" synapse_ids: ["S1", "S4", "S7", "S8", "S13", "S15", "S22", "S25", "S27", "S29"] # S7 and S15 have no 6nm annotations — exclude from 6nm evaluation incomplete_6nm: ["S7", "S15"] raw_dir: "data/raw" annotation_dir: "data/annotations" weights_dir: "weights" patch_size: 512 stride: 2 bead_classes: ["6nm", "12nm"] heatmap: sigmas: 6nm: 1.0 12nm: 1.5 model: backbone: "resnet50" pretrained_weights: "weights/cem500k_mocov2_resnet50.pth.tar" cem500k_url: "https://zenodo.org/records/6453140/files/cem500k_mocov2_resnet50_200ep.pth.tar?download=1" bifpn_channels: 128 bifpn_rounds: 2 num_classes: 2 training: batch_size: 8 n_seeds: 5 n_snapshot_epochs: [150, 170, 190] hard_mining_fraction: 0.7 copy_paste_per_class: 5 phases: phase1: epochs: 60 lr: 1.0e-3 weight_decay: 1.0e-4 freeze_encoder: true phase2: epochs: 60 lr_layer3: 1.0e-5 lr_layer4: 5.0e-5 lr_decoder: 5.0e-4 weight_decay: 1.0e-4 phase3: epochs: 80 lr_stem: 1.0e-6 lr_layer1: 5.0e-6 lr_layer2: 1.0e-5 lr_layer3: 5.0e-5 lr_layer4: 1.0e-4 lr_decoder: 2.0e-4 weight_decay: 1.0e-4 eta_min: 1.0e-7 loss: focal_alpha: 2 focal_beta: 4 lambda_offset: 1.0 early_stopping: patience: 20 monitor: "val_f1_mean" postprocessing: nms_kernel_size: 6nm: 3 12nm: 5 confidence_threshold_sweep: start: 0.05 stop: 0.95 step: 0.01 mask_filter_margin_px: 5 cross_class_nms_distance_px: 8 evaluation: match_radii_px: 6nm: 9 12nm: 15 loocv_val_offset: 1 tta: enabled: true n_geometric: 8 # D4 group: 4 rotations x 2 reflections intensity_factors: [0.9, 1.1] ensemble: n_seeds: 5 snapshot_epochs: [150, 170, 190] # Total ensemble members per fold: 5 seeds x 3 snapshots = 15