{
  "default_seeds": [42, 123, 456],
  "num_candidates_per_seed": 100,
  "num_samples_per_batch": 1,
  "optimization_steps": 128,
  "top_p": 1.0,
  "top_k": 200,
  "cascade_k": 8,
  "beta_min": 50.0,
  "beta_max": 50.0,
  "weights": [1.0, 1.0],
  "require_valid_x0": true,
  "max_x0_retries": 10,
  "targets": {
    "ERBB2": {"builder": "SSCpt", "smiles_length": 80},
    "GNRHR": {"builder": "AoaDau", "smiles_length": 80},
    "NRP1": {"builder": "DSPASN38", "smiles_length": 100}
  },
  "representation_lengths": {"aa": 10, "uaa": 10}
}