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README.md
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@@ -358,32 +358,39 @@ You can also find the same description in the paper or in the PeptiVerse app `Do
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#### 🩸 Hemolysis Prediction
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50% of read blood cells being lysed at x ug/ml concetration (HC50). If HC50 < 100uM, considered as hemolytic, otherwise non-hemolytic, resulting in a binary 0/1 dataset. The predicted probability should therefore be interpreted as a risk indicator, not an exact concentration estimate.
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- Score close to 0.0 = non-hemolytic
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#### 💧 Solubility Prediction
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Outputs a probability (0–1) that a peptide remains soluble in aqueous conditions
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**Output interpretation:**
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- Score close to 1.0 = highly soluble
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- Score close to 0.0 = poorly soluble
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---
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#### 👯 Non-Fouling Prediction
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Higher scores indicate stronger non-fouling behavior, desirable for circulation and surface-exposed applications
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- Score close to
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#### 🪣 Permeability Prediction
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Predicts membrane permeability on a log P scale
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#### ⏱️ Half-Life Prediction
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#### 🔗 Binding Affinity Prediction
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Predicts peptide-protein binding affinity. Requires both peptide and target protein sequence
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**Interpretation:**<br>
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- Scores ≥ 9 correspond to tight binders (K ≤ 10⁻⁹ M, nanomolar to picomolar range)<br>
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--local-dir . \
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--local-dir-use-symlinks False
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```
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## Citation 🌟
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---
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#### 🩸 Hemolysis Prediction
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50% of read blood cells being lysed at x ug/ml concetration (HC50). If HC50 < 100uM, considered as hemolytic, otherwise non-hemolytic, resulting in a binary 0/1 dataset. The predicted probability should therefore be interpreted as a risk indicator, not an exact concentration estimate. <br>
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**Output interpretation:**<br>
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- Score close to 1.0 = high probability of red blood cell membrane disruption<br>
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- Score close to 0.0 = non-hemolytic
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---
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#### 💧 Solubility Prediction
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Outputs a probability (0–1) that a peptide remains soluble in aqueous conditions.<br>
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**Output interpretation:**<br>
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- Score close to 1.0 = highly soluble<br>
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- Score close to 0.0 = poorly soluble<br>
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#### 👯 Non-Fouling Prediction
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Higher scores indicate stronger non-fouling behavior, desirable for circulation and surface-exposed applications.<br>
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**Output interpretation:**<br>
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- Score close to 1.0 = non-fouling<br>
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- Score close to 0.0 = fouling<br>
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#### 🪣 Permeability Prediction
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Predicts membrane permeability on a log P scale.<br>
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**Output interpretation:**<br>
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- Higher values = more permeable (>-6.0)<br>
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- For penetrance predictions, it is a classification prediction, so within the [0, 1] range, closer to 1 indicates more permeable.<br>
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---
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#### ⏱️ Half-Life Prediction
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#### 🔗 Binding Affinity Prediction
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Predicts peptide-protein binding affinity. Requires both peptide and target protein sequence.<br>
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**Interpretation:**<br>
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- Scores ≥ 9 correspond to tight binders (K ≤ 10⁻⁹ M, nanomolar to picomolar range)<br>
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--local-dir . \
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--local-dir-use-symlinks False
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```
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### TODOs
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Bug loading transformer half-life model now, will fix soon.
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## Citation 🌟
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