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+# Plant DNA Designer — container image for the FastAPI web app.
+# Doubles as the Hugging Face Space image (sdk: docker, app_port: 7860).
+#
+#   docker build -t plant-dna-designer .
+#   docker run -p 7860:7860 plant-dna-designer   # open http://localhost:7860
+#
+FROM python:3.12-slim
+
+ENV PIP_NO_CACHE_DIR=1 \
+    PYTHONUNBUFFERED=1 \
+    PYTHONDONTWRITEBYTECODE=1
+
+WORKDIR /app
+
+# Core runtime dependencies (must install cleanly; all ship manylinux wheels for
+# cp312, so no compiler is needed). matplotlib/pytest/httpx from requirements.txt
+# are build/test-only and are intentionally excluded from the runtime image.
+RUN pip install \
+      "fastapi>=0.139.0" \
+      "uvicorn[standard]>=0.50.2" \
+      "jinja2>=3.1.6" \
+      "pydantic>=2.13.4" \
+      "biopython>=1.87" \
+      "numpy>=2.5.0"
+
+# Optional: ViennaRNA gives exact MFE / partition-function folding. The app falls
+# back to a built-in Nussinov estimator when it is absent, so a failure here must
+# NOT break the image — hence the guard.
+RUN pip install "ViennaRNA>=2.7.2" \
+      || echo "ViennaRNA unavailable; falling back to the built-in Nussinov fold."
+
+# Application code (pure-Python core, API, and no-build web frontend).
+COPY cool/ ./cool/
+
+WORKDIR /app/cool
+EXPOSE 7860
+CMD ["python", "-m", "uvicorn", "api.main:app", "--host", "0.0.0.0", "--port", "7860"]