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README.md
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---
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license: apache-2.0
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---
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license: apache-2.0
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tags:
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- medical-imaging
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- ct-generation
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- flow-matching
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- diffusion
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- text-to-3d
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- auto-regressive
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---
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# CTFlow: Video-Inspired Latent Flow Matching for 3D CT Synthesis
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**ICCV 2025 Workshop on Vision-Language Models for 3D Understanding (VLM3D)**
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[[Paper]](https://openaccess.thecvf.com/content/ICCV2025W/VLM3D/papers/Wang_CTFlow_Video-Inspired_Latent_Flow_Matching_for_3D_CT_Synthesis_ICCVW_2025_paper.pdf) | [[GitHub]](https://github.com/WongJiayi/CTFlow)
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---
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## Overview
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CTFlow is a **0.5B latent flow matching transformer** for generating entire 3D CT volumes conditioned on clinical reports.
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Key ideas:
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- Uses the **FLUX A-VAE** as the latent space encoder/decoder
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- Encodes clinical reports with the **CT-CLIP text encoder**
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- Generates CT volumes **auto-regressively block-by-block**, keeping memory tractable while maintaining temporal coherence across slices
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- Trained on **CT-RATE**, a large-scale dataset of 3D CT volumes paired with clinical reports
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---
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## Checkpoint
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This repository contains the pretrained **STDiT-L2** checkpoint (512M parameters, trained for 680,000 steps):
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```
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checkpoint-680000/
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└── denoiser_ema/ ← use this for inference
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```
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---
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## Usage
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See the [GitHub repository](https://github.com/WongJiayi/CTFlow) for full installation instructions, training configs, and inference scripts.
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**Quick inference:**
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```bash
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git clone https://github.com/WongJiayi/CTFlow
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cd CTFlow
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python auto_regressive_generate/main.py \
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--config /path/to/config.yaml \
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--ckpt /path/to/checkpoint-680000/denoiser_ema \
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--embedding /path/to/ct_embedding.pt \
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--output output_frames/ \
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--type full-body
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```
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---
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## Citation
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```bibtex
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@InProceedings{Wang_2025_ICCVW,
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author = {Wang, Jiayi and Reynaud, Hadrien and Erick, Franciskus Xaverius and Kainz, Bernhard},
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title = {CTFlow: Video-Inspired Latent Flow Matching for 3D CT Synthesis},
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booktitle = {Proceedings of the IEEE/CVF International Conference on Computer Vision (ICCV) Workshops},
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year = {2025},
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}
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```
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