Update README.md
Browse files
README.md
CHANGED
|
@@ -72,12 +72,12 @@ model-index:
|
|
| 72 |
|
| 73 |

|
| 74 |
|
| 75 |
-
**GALAX** is a graph-augmented language model
|
| 76 |
-
- **LLaMA3-8B-Instruct** as the language backbone
|
| 77 |
-
- **Graph Attention Network (GAT)**
|
| 78 |
-
- **
|
| 79 |
|
| 80 |
-
|
| 81 |
|
| 82 |
---
|
| 83 |
|
|
|
|
| 72 |
|
| 73 |

|
| 74 |
|
| 75 |
+
**GALAX** is a graph-augmented language model designed for explainable target prioritization in precision medicine. It combines three key components:
|
| 76 |
+
- **LLaMA3-8B-Instruct** as the language backbone, further adapted with the BioMedGraphica corpus and fine-tuned on Target-QA.
|
| 77 |
+
- **Graph Attention Network (GAT)** pretrained on integrated multi-omics data and BioMedGraphica knowledge graphs.
|
| 78 |
+
- **A reinforcement-guided subgraph generator** that enables interpretable reasoning by constructing biologically meaningful subgraphs from multi-omics and knowledge graph signals.
|
| 79 |
|
| 80 |
+
By jointly leveraging **multi-omics features**, **protein–protein interactions**, and **disease–target associations**, GALAX provides an interpretable framework for **CRISPR target prioritization** across diverse cancer cell lines. To support benchmarking and reproducibility, we also introduce the **[Target-QA dataset](https://huggingface.co/datasets/FuhaiLiAiLab/Target-QA)**.
|
| 81 |
|
| 82 |
---
|
| 83 |
|