{ "schema_version": 1, "task": "NCL-stained nucleolar instance segmentation", "status": "experimental_development_candidate_not_adopted", "completed_updates": 375, "checkpoint_sha256": "bc5ea7f25ce9a9f96e9ff510cee20587e1328ac834a0f7f82aee0bc06156d906", "base_checkpoint_sha256": "0f1cc3f7ecdd8a037a57c6c48d9d8921391be4cbce3fa9f13c3e3a2e1253c667", "data_manifest_sha256": "0ae2728c8e85ed94d55ca0baeb54bd72c139aac01a142d7ca6ebe4e8a5a5b7fe", "training_code_sha256": "4d7797c716d9fde458b29ed3b1d07e8b990cbf826560d540a62cf5c0fb94d53a", "inference_code_sha256": "c4b32c7910b3e00804b48794791468dfefedec7896ec770548f34872b4fd9453", "recipe": { "optimizer": "AdamW", "lr_max": 1e-05, "weight_decay": 0.1, "warmup_updates": 100, "batch_size": 1, "rdrop": 0, "augmentation": false }, "environment": { "cellpose": "4.2.1.1", "torch": "2.8.0+cpu", "numpy": "2.2.6", "scipy": "1.16.2" }, "evaluation_summary": { "training_experiments": 1, "training_regions": 2, "training_objects": 8, "development_experiments": 1, "development_regions": 1, "development_objects": 4, "final_test_regions": 0, "matched_product_baseline": { "TP": 3, "FP": 4, "FN": 1, "F1": 0.5454545454545454, "union_Dice": 0.8534045393858478, "total_area_relative_difference": -0.2038369304556355 }, "candidate_product_output": { "TP": 4, "FP": 2, "FN": 0, "F1": 0.8, "union_Dice": 0.9348565872630044, "total_area_relative_difference": -0.02685851318944844 }, "candidate_raw_output": { "TP": 2, "FP": 5, "FN": 2, "F1": 0.36363636363636365, "union_Dice": 0.8992209097763257, "total_area_relative_difference": -0.09160671462829736 }, "limitations": [ "Development-only pilot; not a generalization or final validation claim.", "Product output includes unchanged parent-nucleus and postprocessing stages; raw model output differs.", "Extra split fragments and object-level boundary/area regressions remain.", "Training images are not independent validation.", "Two-human reference agreement, native fluorescence accuracy, and correction burden not measured.", "Not validated for NPM1 staining or cytoplasm." ] } }