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README.md
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- neuropathology
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- image-classification
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- university-of-kentucky
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license: apache-2.0
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datasets:
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- BDSA-neuropathology
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## Model Details
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* **Model Type:** Vision Transformer (ViT) for neuropathology.
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* **Developed by:** Center for Applied Artificial Intelligence (CAAI)
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* **Model Date:** 10/2025
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* **Base Model Architecture:** Dinov2-with-registers-giant (https://huggingface.co/facebook/dinov2-with-registers-giant)
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* **Input:** Image (224x224).
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* **Dataset(s):** The model was trained on data from the University of Kentucky.
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* **Name/Identifier:** UK Alzheimer's Disease Center Neuropathology Whole Slide Image Cohort [BDSA TEST v1.0]
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* **Source:** [UK-ADRC Neuropathology Lab at the University of Kentucky University of Kentucky](https://neuropathlab.createuky.net/)
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* **Description:** The dataset contained 57
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* **Preprocessing:** WSIs were tiled into non-overlapping 224x224 pixel patches at multiple magnification levels (40x, 10x, 2.5x, and 1.25x). For each magnification level, a maximum of 1000 tiles per annotation label were extracted to ensure balanced representation across pathological features.
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* **Annotation :** "Regions of interest (ROIs) for Gray Matter, White Matter, Leptomeninges, Exclude and Superficial Cortex were annotated. Annotations completed by Allison Neltner using a [web-based tool](https://github.com/pitt-bdsa/webapps) developed my Thomas Pearce, MD (UMPC).
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- neuropathology
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- image-classification
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- university-of-kentucky
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- emory-university
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license: apache-2.0
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datasets:
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- BDSA-neuropathology
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## Model Details
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* **Model Type:** Vision Transformer (ViT) for neuropathology.
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* **Developed by:** [Center for Applied Artificial Intelligence (CAAI)](https://caai.ai.uky.edu/) and [Gutman Lab](https://winshipcancer.emory.edu/profiles/gutman-david.php)
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* **Model Date:** 10/2025
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* **Base Model Architecture:** Dinov2-with-registers-giant (https://huggingface.co/facebook/dinov2-with-registers-giant)
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* **Input:** Image (224x224).
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* **Dataset(s):** The model was trained on data from the University of Kentucky.
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* **Name/Identifier:** UK Alzheimer's Disease Center Neuropathology Whole Slide Image Cohort [BDSA TEST v1.0]
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* **Source:** Gutman Lab and [UK-ADRC Neuropathology Lab at the University of Kentucky University of Kentucky](https://neuropathlab.createuky.net/)
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* **Description:** The dataset contained 57 whole slide images (WSIs) of human post-mortem brain tissue sections from UK-ADRC and N patches from the Gutman Lab. Sections were stained with Hematoxylin and Eosin (H&E).
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* **Preprocessing:** WSIs were tiled into non-overlapping 224x224 pixel patches at multiple magnification levels (40x, 10x, 2.5x, and 1.25x). For each magnification level, a maximum of 1000 tiles per annotation label were extracted to ensure balanced representation across pathological features.
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* **Annotation :** "Regions of interest (ROIs) for Gray Matter, White Matter, Leptomeninges, Exclude and Superficial Cortex were annotated. Annotations completed by Allison Neltner using a [web-based tool](https://github.com/pitt-bdsa/webapps) developed my Thomas Pearce, MD (UMPC).
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