File size: 7,242 Bytes
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def get_information(length):
if length < 60:
return {
"AF2_ipae": [3.84, 5.03, 6.07, 6.12, 21.36, 10.57, 8.75, 8.24, 23.1, 15.32],
"ptx_iptm": [
0.95,
0.9,
0.83,
0.64,
0.54,
0.49,
0.89,
0.67,
0.28,
0.1,
],
"ptx_temp_iptm": [
0.95,
0.91,
0.87,
0.84,
0.44,
0.6,
0.88,
0.58,
0.68,
0.35,
],
"AF2_SR": [44.89, 37.5, 28.41, 19.6, 3.12, 10.23, 26.42, 13.92, 0.28, 5.68],
"ptx_sr": [55.7, 32.4, 11.9, 3.1, 2.3, 0.3, 33.0, 3.7, 0.0, 0.0],
"ptx_temp_sr": [58.5, 50.0, 17.0, 15.9, 0.6, 0.0, 31.2, 0.6, 1.1, 0.0],
"count": "Length 50-60",
}
elif length < 80 and length >= 60:
return {
"AF2_ipae": [3.99, 4.97, 5.73, 6.37, 17.19, 9.37, 8.83, 8.04, 22.71, 16.09],
"ptx_iptm": [
0.94,
0.9,
0.88,
0.59,
0.58,
0.52,
0.88,
0.76,
0.33,
0.09,
],
"ptx_temp_iptm": [
0.95,
0.91,
0.88,
0.86,
0.54,
0.58,
0.88,
0.66,
0.71,
0.36,
],
"AF2_SR": [
44.79,
44.35,
33.93,
20.39,
5.65,
13.39,
28.87,
19.49,
0.74,
6.55,
],
"ptx_sr": [54.6, 36.6, 16.5, 2.8, 2.2, 0.1, 33.5, 7.1, 0.0, 0.0],
"ptx_temp_sr": [62.5, 45.2, 22.0, 19.6, 0.9, 0.0, 37.5, 3.9, 3.9, 0.0],
"count": "Length 60-80",
}
elif length < 100 and length >= 80:
return {
"AF2_ipae": [4.03, 5.08, 5.58, 6.12, 14.36, 8.87, 9.79, 7.96, 22.57, 16.02],
"ptx_iptm": [
0.94,
0.88,
0.86,
0.56,
0.64,
0.51,
0.87,
0.82,
0.33,
0.09,
],
"ptx_temp_iptm": [
0.96,
0.9,
0.88,
0.87,
0.61,
0.59,
0.88,
0.71,
0.72,
0.37,
],
"AF2_SR": [49.4, 45.09, 38.24, 21.28, 6.55, 15.18, 16.22, 23.51, 0.6, 4.91],
"ptx_sr": [59.4, 30.2, 18.9, 2.1, 3.6, 0.0, 24.4, 9.1, 0.0, 0.0],
"ptx_temp_sr": [70.5, 43.5, 23.2, 26.5, 1.8, 0.0, 29.2, 6.2, 5.4, 0.0],
"count": "Length 80-100",
}
elif length < 120 and length >= 100:
return {
"AF2_ipae": [
4.08,
5.28,
5.69,
6.73,
12.75,
8.38,
10.29,
8.06,
22.85,
13.73,
],
"ptx_iptm": [
0.94,
0.88,
0.84,
0.44,
0.6,
0.54,
0.85,
0.84,
0.26,
0.09,
],
"ptx_temp_iptm": [
0.96,
0.9,
0.87,
0.88,
0.55,
0.58,
0.86,
0.79,
0.69,
0.47,
],
"AF2_SR": [47.77, 38.99, 42.11, 15.62, 7.59, 16.52, 12.5, 25.3, 1.34, 5.95],
"ptx_sr": [60.3, 25.1, 15.6, 1.3, 2.5, 0.0, 18.9, 14.3, 0.0, 0.0],
"ptx_temp_sr": [71.4, 33.9, 20.5, 23.2, 1.5, 0.0, 21.7, 9.5, 4.2, 0.0],
"count": "Length 100-120",
}
elif length < 140 and length >= 120:
return {
"AF2_ipae": [4.16, 5.51, 5.78, 7.66, 8.48, 9.19, 11.08, 8.12, 22.62, 14.74],
"ptx_iptm": [
0.93,
0.87,
0.83,
0.37,
0.62,
0.51,
0.83,
0.84,
0.27,
0.09,
],
"ptx_temp_iptm": [
0.95,
0.87,
0.87,
0.88,
0.65,
0.59,
0.82,
0.85,
0.74,
0.52,
],
"AF2_SR": [48.07, 34.82, 43.45, 12.5, 13.1, 12.8, 8.04, 22.47, 1.19, 4.61],
"ptx_sr": [52.2, 22.6, 11.6, 0.6, 1.6, 0.3, 14.4, 15.2, 0.0, 0.0],
"ptx_temp_sr": [66.7, 23.2, 21.4, 19.0, 4.2, 0.0, 14.6, 11.9, 4.2, 0.0],
"count": "Length 120-140",
}
else:
return {
"AF2_ipae": [4.22, 5.56, 5.74, 9.47, 6.74, 9.74, 11.38, 8.37, 23.94, 17.1],
"ptx_iptm": [
0.93,
0.86,
0.8,
0.31,
0.72,
0.52,
0.81,
0.83,
0.23,
0.09,
],
"ptx_temp_iptm": [
0.95,
0.87,
0.89,
0.84,
0.71,
0.56,
0.79,
0.87,
0.72,
0.42,
],
"AF2_SR": [45.17, 32.95, 39.2, 10.51, 22.73, 11.36, 7.95, 19.6, 1.7, 4.26],
"ptx_sr": [34.7, 18.8, 9.7, 0.6, 3.4, 0.3, 8.2, 22.4, 0.0, 0.0],
"ptx_temp_sr": [57.4, 21.0, 23.9, 11.9, 6.2, 0.0, 8.5, 19.9, 4.5, 0.0],
"count": "Length 140-150",
}
labels = [
"BHRF1",
"PDL1",
"IR",
"TrkA",
"SC2RBD",
"VEGF-A",
"IL7RA",
"H1",
"IL17A",
"TNFa",
]
difficulty_to_color = {
"easy": "#086BFFE8",
"hard": "#086BFFE8",
"very_hard": "#086BFFE8",
}
font_path = os.path.join(os.path.dirname(__file__), "Helvetica-Regular.ttf")
text_full = (
"Your submitted case is positioned at the difficulty level shown below, based on evaluations from"
+ " both AlphaFold2 model (initial guess) and Protenix model. If you believe the target you provided does not"
+ " match the expected difficulty, you may adjust the input model settings: hotspot location, binder length,"
+ " and target file resolution."
)
text_preview = (
"Your submitted case is positioned at the difficulty level shown below, based on evaluations from"
+ " AlphaFold2 model (initial guess). If you believe the target you provided does not"
+ " match the expected difficulty, you may adjust the input model settings: hotspot location, binder length,"
+ " and target file resolution."
)
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