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import warnings
warnings.filterwarnings("ignore", category=UserWarning, module="torch.jit._check")
import copy
import math
import os
import sys
from functools import partial

import wandb
import torch
torch.multiprocessing.set_sharing_strategy('file_system')

import resource
rlimit = resource.getrlimit(resource.RLIMIT_NOFILE)
resource.setrlimit(resource.RLIMIT_NOFILE, (64000, rlimit[1]))

import yaml

SCRIPT_DIR = os.path.dirname(os.path.abspath(__file__))
PROJECT_DIR = os.path.dirname(SCRIPT_DIR)
MODEL_DIR = os.path.join(PROJECT_DIR, "model")
if MODEL_DIR not in sys.path:
    sys.path.insert(0, MODEL_DIR)

from utils.diffusion_utils import t_to_sigma as t_to_sigma_compl
from datasets.pdbbind import construct_loader
from utils.parsing import parse_train_args
from utils.training import train_epoch, test_epoch, loss_function, inference_epoch,inference_epoch_parallel
from utils.utils import save_yaml_file, get_optimizer_and_scheduler, get_model, ExponentialMovingAverage
import datetime
from loguru import logger
# from models.score_model_mdn_energy import TensorProductEnergyModel
def train(args, model, optimizer, scheduler,  ema_weights,train_loader, val_loader, t_to_sigma, run_dir,accelerator):
    best_val_loss = math.inf
    best_val_inference_value = math.inf if args.inference_earlystop_goal == 'min' else 0
    best_epoch = 0
    best_val_inference_epoch = 0
    loss_fn = partial(loss_function, tr_weight=args.tr_weight, rot_weight=args.rot_weight,
                      tor_weight=args.tor_weight, no_torsion=args.no_torsion)
    if accelerator.is_local_main_process:
        logger.info("Starting training...")
        
        logger.info('Load val inference dataset ...')
    val_inference_datalist = val_loader.dataset.get_complexs_list(args.num_inference_complexes)
    if accelerator.is_local_main_process:
        logger.info(f'Size of dataset is : {len(val_inference_datalist)}.')
    scheduler.scheduler.num_bad_epochs = 1
    for epoch in range(args.n_epochs):
        if accelerator.is_local_main_process:
            if epoch % 5 == 0: logger.info(f"Run name: {args.run_name}")
        logs = {}
        #################trainging ########################
        # logger.info('model intance',isinstance(model,TensorProductEnergyModel))
        train_losses = train_epoch(model, train_loader, optimizer, device, t_to_sigma, loss_fn,accelerator,ema_weights)
        # accelerator.wait_for_everyone()
        if accelerator.is_local_main_process:
            nowtime = datetime.datetime.now().strftime('%Y-%m-%d %H:%M:%S')
            logger.info(f"epoch【{epoch}】@{nowtime} --> train_metric=")
            logger.info("Epoch {}: Training loss {:.4f}  tr {:.4f}   rot {:.4f}   tor {:.4f}"
                .format(epoch, train_losses['loss'], train_losses['tr_loss'], train_losses['rot_loss'],
                        train_losses['tor_loss']),flush=True)
        # accelerator.wait_for_everyone()
        # unwrapped_model = accelerator.unwrap_model(model)
        ema_weights.store(model.parameters())
        if args.use_ema: ema_weights.copy_to(model.parameters()) # load ema parameters into model for running validation and inference
        ############### trainging end#######################

        val_losses = test_epoch(model, val_loader, device, t_to_sigma, loss_fn, accelerator,args.test_sigma_intervals,model_type=args.model_type)
        #####################
        accelerator.wait_for_everyone()
        if accelerator.is_local_main_process:
            nowtime = datetime.datetime.now().strftime('%Y-%m-%d %H:%M:%S')
            logger.info(f"epoch【{epoch}】@{nowtime} --> eval_metric=")
            logger.info("Epoch {}: Validation loss {:.4f}  tr {:.4f}   rot {:.4f}   tor {:.4f}"
                .format(epoch, val_losses['loss'], val_losses['tr_loss'], val_losses['rot_loss'], val_losses['tor_loss']))
        if args.val_inference_freq != None and (epoch + 1) % args.val_inference_freq == 0 and (epoch + 1) > args.skip_inference_freq:
            
            inf_metrics = inference_epoch_parallel(model, val_inference_datalist, device, t_to_sigma, args,accelerator)
            if accelerator.is_local_main_process:
                nowtime = datetime.datetime.now().strftime('%Y-%m-%d %H:%M:%S')
                logger.info(f"epoch【{epoch}】@{nowtime} --> inference_metric=")
                logger.info("Epoch {}: Val inference rmsds_lt2 {:.3f} rmsds_lt5 {:.3f}"
                    .format(epoch, inf_metrics['rmsds_lt2'], inf_metrics['rmsds_lt5']))
                
            logs.update({'valinf_' + k: v for k, v in inf_metrics.items()}, step=epoch + 1)

        if not args.use_ema: ema_weights.copy_to(model.parameters())
        accelerator.wait_for_everyone()
        # ema weight state dict
        unwrapped_model = accelerator.unwrap_model(model)
        ema_state_dict = copy.deepcopy(unwrapped_model.state_dict() if device.type == 'cuda' else unwrapped_model.state_dict())
        # last model weight state dict
        ema_weights.restore(model.parameters())
        accelerator.wait_for_everyone()
        unwrapped_model = accelerator.unwrap_model(model)
        # ema_state_dict = copy.deepcopy(unwrapped_model.state_dict() if device.type == 'cuda' else unwrapped_model.state_dict())
        state_dict = unwrapped_model.state_dict() if device.type == 'cuda' else unwrapped_model.state_dict()
        
        logs.update({'train_' + k: v for k, v in train_losses.items()})
        logs.update({'val_' + k: v for k, v in val_losses.items()})
        logs['current_lr'] = optimizer.param_groups[0]['lr']
        
        if args.wandb and accelerator.is_local_main_process:
            wandb.log(logs, step=epoch + 1)
       

        if args.inference_earlystop_metric in logs.keys() and \
                (args.inference_earlystop_goal == 'min' and logs[args.inference_earlystop_metric] <= best_val_inference_value or
                args.inference_earlystop_goal == 'max' and logs[args.inference_earlystop_metric] >= best_val_inference_value):
            best_val_inference_value = logs[args.inference_earlystop_metric]
            best_val_inference_epoch = epoch
            if accelerator.is_local_main_process:
                torch.save(state_dict, os.path.join(run_dir, 'best_inference_epoch_model.pt'))
                torch.save(ema_state_dict, os.path.join(run_dir, 'best_ema_inference_epoch_model.pt'))
            
        if val_losses['loss'] <= best_val_loss:
            best_val_loss = val_losses['loss']
            best_epoch = epoch
            if accelerator.is_local_main_process:
                torch.save(state_dict, os.path.join(run_dir, 'best_model.pt'))
                torch.save(ema_state_dict, os.path.join(run_dir, 'best_ema_model.pt'))
        
        if scheduler and (epoch + 1) % args.val_inference_freq == 0 and (epoch + 1) > args.skip_inference_freq:
            if args.val_inference_freq is not None and (epoch + 1) > args.skip_inference_freq:

                scheduler.step(best_val_inference_value)
                
            else:

                scheduler.step(-1*val_losses['loss'])
            if scheduler.scheduler.num_bad_epochs < accelerator.num_processes:
                scheduler.scheduler.num_bad_epochs = 1

        if accelerator.is_local_main_process:
            # accelerator.wait_for_everyone()
            # unwrapped_optimizer = accelerator.unwrap_model(optimizer)
            torch.save({
            'epoch': epoch,
            'model': state_dict,
            'optimizer': optimizer.state_dict(),
            'ema_weights': ema_weights.state_dict(),
        }, os.path.join(run_dir, 'last_model.pt'))
    if accelerator.is_local_main_process:

        logger.info("Best Validation Loss {} on Epoch {}".format(best_val_loss, best_epoch))
        logger.info("Best inference metric {} on Epoch {}".format(best_val_inference_value, best_val_inference_epoch))
    if args.wandb:
        wandb.finish()

# from accelerate.utils import DummyOptim, DummyScheduler, set_seed
def main_function():
    import typing
    args = parse_train_args()
    if args.config:
        config_dict = yaml.load(args.config, Loader=yaml.FullLoader)
        arg_dict = args.__dict__
        for key, value in config_dict.items():
            if isinstance(value, list):
                for v in value:
                    arg_dict[key].append(v)
            elif isinstance(value, typing.Dict):
                arg_dict[key] = value['value']
            else:
                arg_dict[key] = value
        # args.config = args.config.name 
    # logger.info(args)
    run_dir = os.path.join(args.log_dir, args.run_name)
    os.makedirs(run_dir, exist_ok=True)
    logger.add(os.path.join(run_dir,'LogFile.log'), rotation='100 MB')
    logger.info(f'Args:{args}')
    if accelerator.is_local_main_process:
        # os.makedirs(args.log_dir, exist_ok=True)
        # args.run_name =args.run_name + datetime.datetime.now().strftime('%Y-%m-%d_%H-%M-%S')
        if args.wandb:
            wandb.login(key = 'yourkey')
            
            wandb.init(
                entity='SurfDock',
                settings=wandb.Settings(start_method="fork"),
                project=args.project,
                name=args.run_name ,
                dir = args.wandb_dir,
                config=args
            )
            # wandb.log({'numel': numel})
    # args.run_name = args.run_name + datetime.datetime.now().strftime('%Y-%m-%d_%H-%M-%S')
    assert (args.inference_earlystop_goal == 'max' or args.inference_earlystop_goal == 'min')
    if args.val_inference_freq is not None and args.scheduler is not None:
        assert (args.scheduler_patience > args.val_inference_freq) # otherwise we will just stop training after args.scheduler_patience epochs
    if args.cudnn_benchmark:
        torch.backends.cudnn.benchmark = True
    # construct loader
    t_to_sigma = partial(t_to_sigma_compl, args=args)
    train_loader, val_loader = construct_loader(args, t_to_sigma)
    # logger.info(" t_to_sigma: ",  t_to_sigma)
    model = get_model(args, device, t_to_sigma=t_to_sigma,model_type = args.model_type)

    optimizer, scheduler = get_optimizer_and_scheduler(args,model, accelerator,scheduler_mode='max')
    ema_weights = ExponentialMovingAverage(model.parameters(),decay=args.ema_rate)
    #################################################
    if args.restart_dir:
        try:
            dict = torch.load(f'{args.restart_dir}/last_model.pt', map_location=torch.device('cpu'))
            if args.restart_lr is not None: dict['optimizer']['param_groups'][0]['lr'] = args.restart_lr
            optimizer.load_state_dict(dict['optimizer'])
            model.load_state_dict(dict['model'], strict=True)
            if hasattr(args, 'ema_rate'):
                ema_weights.load_state_dict(dict['ema_weights'], device=device)
            logger.info("Restarting from epoch: {}".format(dict['epoch']))
        except Exception as e:
            logger.info(f"Exception: {e}")
            dict = torch.load(f'{args.restart_dir}/best_model.pt', map_location=torch.device('cpu'))
            model.module.load_state_dict(dict, strict=True)
            logger.info("Due to exception had to take the best epoch and no optimiser")
    #################################################
    model = accelerator.prepare(model)
    optimizer, train_loader, val_loader, scheduler = accelerator.prepare(
    optimizer,train_loader, val_loader, scheduler)

    numel = sum([p.numel() for p in model.parameters()])
    if accelerator.is_local_main_process:
        logger.info(f'Model with {numel} parameters')
    # record parameters
    # run_dir = os.path.join(args.log_dir, args.run_name)
    yaml_file_name = os.path.join(run_dir, 'model_parameters.yml')
    save_yaml_file(yaml_file_name, args.__dict__)
    args.device = device
    train(args, model, optimizer, scheduler, ema_weights,train_loader, val_loader, t_to_sigma, run_dir,accelerator)
    # wandb.finish()
if __name__ == '__main__':
    from accelerate import Accelerator
    from accelerate.utils import DistributedDataParallelKwargs
    kwargs = DistributedDataParallelKwargs(find_unused_parameters=True)
    accelerator = Accelerator(kwargs_handlers=[kwargs])
    from accelerate.utils import set_seed

    device = accelerator.device
    set_seed(42)
    # accelerator = Accelerator(mixed_precision=mixed_precision)
    logger.info(f'device {str(accelerator.device)} is used!')
    # device = torch.device('cuda:0' if torch.cuda.is_available() else 'cpu')
    main_function()