SimpleFold / config /model /default.yaml
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_target_: models.simplefold.simplefold.SimpleFold
ema_decay: 0.999
clip_grad_norm_val: 2.0
use_rigid_align: True
smooth_lddt_loss_weight: 1.0
lddt_cutoff: 15.0
esm_model: "esm2_3B"
lddt_weight_schedule: False
sample_dir: ${paths.sample_dir}
architecture:
esm_model: ${model.esm_model}
path:
_target_: models.simplefold.flow.LinearPath
loss:
_target_: torch.nn.MSELoss
reduction: 'none'
reduce: False
optimizer:
_target_: torch.optim.AdamW
_partial_: true
lr: 1e-4
weight_decay: 0.0
max_steps: ???
scheduler:
_target_: onescience.utils.simplefold.lr_scheduler.LinearWarmup
_partial_: true
min_lr: 1e-6
max_lr: ${model.optimizer.lr}
warmup_steps: 10
processor:
scale: 16.0
ref_scale: 5.0
multiplicity: 16