File size: 3,994 Bytes
7a92197 |
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 |
# Example GraphQL Queries for Cancer@Home v2
## Basic Queries
### Get all genes
```graphql
query {
genes(limit: 10) {
gene_id
symbol
name
chromosome
gene_type
}
}
```
### Get specific gene by symbol
```graphql
query {
gene(symbol: "TP53") {
gene_id
symbol
name
chromosome
start_position
end_position
}
}
```
### Get mutations for a specific gene
```graphql
query {
mutations(gene: "TP53", limit: 20) {
mutation_id
chromosome
position
reference
alternate
consequence
variant_type
quality
}
}
```
### Get mutations on a chromosome
```graphql
query {
mutations(chromosome: "chr17", limit: 50) {
mutation_id
position
reference
alternate
consequence
}
}
```
## Patient Queries
### Get all patients
```graphql
query {
patients(limit: 100) {
patient_id
project_id
age
gender
race
vital_status
}
}
```
### Get patients by project
```graphql
query {
patients(project_id: "TCGA-BRCA") {
patient_id
age
gender
vital_status
}
}
```
### Get patients by cancer type
```graphql
query {
patients(cancer_type: "BRCA", limit: 50) {
patient_id
age
gender
race
}
}
```
## Cancer Type Queries
### Get all cancer types
```graphql
query {
cancerTypes {
cancer_type_id
name
tissue
disease_type
}
}
```
### Get statistics for a cancer type
```graphql
query {
cancerStatistics(cancer_type_id: "BRCA") {
cancer_type
total_patients
total_mutations
avg_mutations_per_patient
}
}
```
## Mutation Analysis
### Get mutation frequency
```graphql
query {
mutationFrequency(mutation_id: "MUT-TP53-001") {
mutation_id
patients_with_mutation
total_patients
frequency
}
}
```
## Complex Queries
### Combined gene and mutation data
```graphql
query {
gene(symbol: "BRCA1") {
symbol
name
chromosome
}
mutations(gene: "BRCA1") {
mutation_id
position
consequence
quality
}
}
```
### Multiple cancer statistics
```graphql
query {
breastCancer: cancerStatistics(cancer_type_id: "BRCA") {
cancer_type
total_patients
total_mutations
}
lungCancer: cancerStatistics(cancer_type_id: "LUAD") {
cancer_type
total_patients
total_mutations
}
}
```
## Using Variables
### Query with variables
```graphql
query GetGeneInfo($geneSymbol: String!) {
gene(symbol: $geneSymbol) {
symbol
name
chromosome
}
mutations(gene: $geneSymbol) {
mutation_id
position
consequence
}
}
```
Variables:
```json
{
"geneSymbol": "TP53"
}
```
### Pagination example
```graphql
query GetMutations($limit: Int = 10) {
mutations(limit: $limit) {
mutation_id
chromosome
position
}
}
```
Variables:
```json
{
"limit": 25
}
```
## Filtering Examples
### Get high-quality mutations
```graphql
query {
mutations(gene: "KRAS", limit: 100) {
mutation_id
quality
consequence
}
}
```
### Get patients by demographics
```graphql
query {
patients(project_id: "TCGA-BRCA") {
patient_id
age
gender
race
vital_status
}
}
```
## Tips for Using GraphQL
1. **Use the GraphQL Playground**: Navigate to http://localhost:5000/graphql for an interactive interface with autocomplete and documentation
2. **Request only needed fields**: GraphQL allows you to request exactly the data you need, improving performance
3. **Combine multiple queries**: Use aliases to fetch different datasets in a single request
4. **Use variables**: Make queries reusable by parameterizing them with variables
5. **Explore the schema**: Use the GraphQL Playground's "Docs" panel to see all available queries and fields
|