Update README.md
Browse files
README.md
CHANGED
|
@@ -1,12 +1,35 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
<p align="center"> <b> Predictive Radiomics for Evaluation of Cancer Immune SignaturE in Glioblastoma | PRECISE-GBM </b> </p>
|
| 2 |
|
| 3 |
<p align="center">
|
| 4 |
<img src="PRECISE-GBM_GUI_logo%20(1).png" alt="PRECISE-GBM Logo">
|
| 5 |
</p>
|
| 6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
| 7 |
<b> Project: PRECISE-GBM - Model training & retraining helpers </b>
|
| 8 |
|
| 9 |
-
Overview
|
| 10 |
|
| 11 |
This repository contains code to train models (Gaussian Mixture labelling + SVM and ensemble classifiers) and to persist all artifacts required to reproduce or retrain models on new data. It includes:
|
| 12 |
|
|
@@ -20,7 +43,7 @@ This repo also includes helper files to make it ready for GitHub:
|
|
| 20 |
- `LICENSE` β MIT license
|
| 21 |
- GitHub Actions workflow for CI (pytest smoke test)
|
| 22 |
|
| 23 |
-
Getting started (Windows PowerShell)
|
| 24 |
|
| 25 |
1) Create and activate a virtual environment
|
| 26 |
|
|
@@ -44,7 +67,7 @@ python Scenario_heldout_final_PRECISE.py
|
|
| 44 |
|
| 45 |
The training script will create model files under `models_LM22/` and `models_GBM/` and write metadata JSONs next to each joblib model (selected features, params, cv results) as well as group-level JSON summaries.
|
| 46 |
|
| 47 |
-
Retraining
|
| 48 |
|
| 49 |
See `README_RETRAIN.md` for detailed CLI and notebook examples. Short example:
|
| 50 |
|
|
@@ -55,40 +78,46 @@ python retrain_helper.py \
|
|
| 55 |
--label-col "label"
|
| 56 |
```
|
| 57 |
|
| 58 |
-
Notes
|
| 59 |
|
| 60 |
- The training script contains hard-coded absolute paths to data files. Before running on another machine, update the `scenarios_*` file paths or place the datasets in the same paths.
|
| 61 |
- Retrain helper auto-detects model type when `--model-type` is omitted by looking for `{prefix}_svm_params.json` or `{prefix}_ens_params.json`.
|
| 62 |
- YAML config support for retrain requires PyYAML (`pip install pyyaml`).
|
| 63 |
|
| 64 |
-
CI
|
| 65 |
|
| 66 |
A basic GitHub Actions workflow runs a smoke pytest to ensure the retrain helper imports and basic pipeline construction works. It does not run heavy training.
|
| 67 |
|
| 68 |
-
Contributing
|
| 69 |
|
| 70 |
See `CONTRIBUTING.md` for guidance on opening issues and PRs.
|
| 71 |
|
| 72 |
-
License
|
| 73 |
|
| 74 |
-
This project is released under the MIT License β see `LICENSE`.
|
| 75 |
|
| 76 |
-
Citation
|
| 77 |
-
Please use the following
|
| 78 |
|
| 79 |
2025
|
| 80 |
|
| 81 |
-
|
| 82 |
|
| 83 |
-
|
| 84 |
|
| 85 |
2024
|
| 86 |
|
| 87 |
-
|
|
|
|
|
|
|
| 88 |
|
| 89 |
-
β’ Ghimire P, Modat M, Booth T. A radiogenomic machine learning based study to identify Predictive Radiomics for Evaluation of Cancer Immune SignaturE in IDHw Glioblastoma. Neuro-Oncology. Oct 2024; 26(suppl_7): vii3
|
| 90 |
|
|
|
|
| 91 |
|
|
|
|
| 92 |
|
|
|
|
| 93 |
|
|
|
|
| 94 |
|
|
|
|
|
|
| 1 |
+
---
|
| 2 |
+
license: mit
|
| 3 |
+
language:
|
| 4 |
+
- en
|
| 5 |
+
metrics:
|
| 6 |
+
- accuracy
|
| 7 |
+
- precision
|
| 8 |
+
pipeline_tag: image-classification
|
| 9 |
+
tags:
|
| 10 |
+
- biology
|
| 11 |
+
- cancer
|
| 12 |
+
- glioblastoma
|
| 13 |
+
- brain
|
| 14 |
+
- multimodal
|
| 15 |
+
- radiogenomics
|
| 16 |
+
- radiomics
|
| 17 |
+
- immune
|
| 18 |
+
- classifier
|
| 19 |
+
---
|
| 20 |
<p align="center"> <b> Predictive Radiomics for Evaluation of Cancer Immune SignaturE in Glioblastoma | PRECISE-GBM </b> </p>
|
| 21 |
|
| 22 |
<p align="center">
|
| 23 |
<img src="PRECISE-GBM_GUI_logo%20(1).png" alt="PRECISE-GBM Logo">
|
| 24 |
</p>
|
| 25 |
|
| 26 |
+
[](https://opensource.org/licenses/MIT)
|
| 27 |
+
|
| 28 |
+
This repository contains an AI-based training and retraining pipeline for Predictive Radiomics for Evaluation of Cancer Immune SignaturE in Glioblastoma (PRECISE-GBM). It is the multimodal radiogenomic framework that integrates MRI radiomics, genomics, and immune signatures for patient stratification.
|
| 29 |
+
|
| 30 |
<b> Project: PRECISE-GBM - Model training & retraining helpers </b>
|
| 31 |
|
| 32 |
+
## π Overview
|
| 33 |
|
| 34 |
This repository contains code to train models (Gaussian Mixture labelling + SVM and ensemble classifiers) and to persist all artifacts required to reproduce or retrain models on new data. It includes:
|
| 35 |
|
|
|
|
| 43 |
- `LICENSE` β MIT license
|
| 44 |
- GitHub Actions workflow for CI (pytest smoke test)
|
| 45 |
|
| 46 |
+
## π Getting started (Windows PowerShell)
|
| 47 |
|
| 48 |
1) Create and activate a virtual environment
|
| 49 |
|
|
|
|
| 67 |
|
| 68 |
The training script will create model files under `models_LM22/` and `models_GBM/` and write metadata JSONs next to each joblib model (selected features, params, cv results) as well as group-level JSON summaries.
|
| 69 |
|
| 70 |
+
## π Retraining
|
| 71 |
|
| 72 |
See `README_RETRAIN.md` for detailed CLI and notebook examples. Short example:
|
| 73 |
|
|
|
|
| 78 |
--label-col "label"
|
| 79 |
```
|
| 80 |
|
| 81 |
+
## πNotes
|
| 82 |
|
| 83 |
- The training script contains hard-coded absolute paths to data files. Before running on another machine, update the `scenarios_*` file paths or place the datasets in the same paths.
|
| 84 |
- Retrain helper auto-detects model type when `--model-type` is omitted by looking for `{prefix}_svm_params.json` or `{prefix}_ens_params.json`.
|
| 85 |
- YAML config support for retrain requires PyYAML (`pip install pyyaml`).
|
| 86 |
|
| 87 |
+
## π CI
|
| 88 |
|
| 89 |
A basic GitHub Actions workflow runs a smoke pytest to ensure the retrain helper imports and basic pipeline construction works. It does not run heavy training.
|
| 90 |
|
| 91 |
+
## π Contributing
|
| 92 |
|
| 93 |
See `CONTRIBUTING.md` for guidance on opening issues and PRs.
|
| 94 |
|
| 95 |
+
## π License
|
| 96 |
|
| 97 |
+
This project is released under the MIT License β see `LICENSE`. [MIT License](https://opensource.org/licenses/MIT).
|
| 98 |
|
| 99 |
+
## π Citation
|
| 100 |
+
Please use the following citations when using the repository.
|
| 101 |
|
| 102 |
2025
|
| 103 |
|
| 104 |
+
> **Ghimire P, Modat M, Booth T**. *Predictive radiogenomic AI Model for patient stratification in brain tumor immunotherapy trials. Neuro-oncology. Oct 2025; 26(Suppl_3): iii58βiii59. doi: https://doi.org/10.1093/neuonc/noaf193.188*
|
| 105 |
|
| 106 |
+
> **Ghimire P, Modat M, Booth T**. *Radiogenomic AI model predicts immune status in IDH wildtype glioblastoma: PRECISE-GBM study. RCR open. Jan 2025; 3(1): 100234*
|
| 107 |
|
| 108 |
2024
|
| 109 |
|
| 110 |
+
> **Ghimire P, Modat M, Booth T**. *A machine Learning bases predictive radiomics for evaluation of cancer immune signature in glioblastoma: the PRECISE-GBM study. Neuro-Oncology. Oct 2024; 26(suppl_5): v25.*
|
| 111 |
+
|
| 112 |
+
> **Ghimire P, Modat M, Booth T**. *A radiogenomic machine learning based study to identify Predictive Radiomics for Evaluation of Cancer Immune SignaturE in IDHw Glioblastoma. Neuro-Oncology. Oct 2024; 26(suppl_7): vii3*
|
| 113 |
|
|
|
|
| 114 |
|
| 115 |
+
**Contact**:
|
| 116 |
|
| 117 |
+
**Dr Prajwal Ghimire**
|
| 118 |
|
| 119 |
+
**MBBS MRCSEd MSc PhD'26**
|
| 120 |
|
| 121 |
+
School of Biomedical Engineering & Imaging Sciences, King's College London
|
| 122 |
|
| 123 |
+
Email: [prajwal.1.ghimire@kcl.ac.uk](mailto:prajwal.1.ghimire@kcl.ac.uk)
|