---
license: cc-by-nd-4.0
language:
- en
library_name: pytorch
tags:
- eeg
- biosignal
- foundation-model
- self-supervised
- masked-modeling
- windowed-alternating-attention
- neuroscience
datasets:
- TUEG
- SEED
- BOAS
- SleepEDFx
- BCI-NER
- GWD
- CHB-MIT
- Neonate
- PhysioNet-MI
- SHU-MI
- TUAB
- STEW
- SEED-VIG
- ISRUC
- Mumtaz
- MentalArithmetic
- SEED-V
metrics:
- roc_auc
- f1
- nrmse
model-index:
- name: S-CEReBrO
results:
- task:
type: time-series-classification
name: Seizure Detection
dataset:
type: CHB-MIT
name: CHB-MIT
metrics:
- type: roc_auc
value: 87.45
name: AUROC
- task:
type: time-series-classification
name: Seizure Detection
dataset:
type: Neonate
name: Neonate
metrics:
- type: roc_auc
value: 85.76
name: AUROC
- task:
type: time-series-classification
name: Motor Imagery Classification
dataset:
type: PhysioNet-MI
name: PhysioNet-MI
metrics:
- type: f1
value: 60.93
name: Weighted F1
- task:
type: time-series-classification
name: Motor Imagery Classification
dataset:
type: SHU-MI
name: SHU-MI
metrics:
- type: roc_auc
value: 66.48
name: AUROC
- task:
type: time-series-classification
name: Abnormal Classification
dataset:
type: TUAB
name: TUAB
metrics:
- type: roc_auc
value: 89.30
name: AUROC
- task:
type: time-series-classification
name: Mental Workload Classification
dataset:
type: STEW
name: STEW
metrics:
- type: f1
value: 52.90
name: Weighted F1
- task:
type: time-series-regression
name: Vigilance Estimation
dataset:
type: SEED-VIG
name: SEED-VIG
metrics:
- type: nrmse
value: 0.93
name: NRMSE
- task:
type: time-series-classification
name: Sleep Stage Classification
dataset:
type: ISRUC
name: ISRUC
metrics:
- type: f1
value: 78.23
name: Weighted F1
- task:
type: time-series-classification
name: Mental Disorder Diagnosis
dataset:
type: Mumtaz
name: Mumtaz
metrics:
- type: roc_auc
value: 98.23
name: AUROC
- task:
type: time-series-classification
name: Mental Stress Detection
dataset:
type: MentalArithmetic
name: MentalArithmetic
metrics:
- type: roc_auc
value: 68.97
name: AUROC
- task:
type: time-series-classification
name: Emotion Recognition
dataset:
type: SEED-V
name: SEED-V
metrics:
- type: f1
value: 28.16
name: Weighted F1
---
S-CEReBrO: Breaking the Memory Barrier in Continuous EEG Monitoring
**S-CEReBrO** (Streaming CEReBrO) is an **EEG foundation model** designed for **continuous monitoring**.
S-CEReBrO addresses the memory overflow bottleneck of continuous monitoring by utilizing a novel **Windowed Alternating Attention mechanism**. This factorizes attention computation into fixed-size spatiotemporal windows, guaranteeing a **constant KV cache memory** as only the active window requires resident attention maps.
---
## ๐ License & Usage Policy (Weights)
**Weights license:** The released model weights are licensed under **Creative Commons AttributionโNoDerivatives 4.0 (CC BY-ND 4.0)**. This section summarizes the practical implications for users. *This is not legal advice; please read the full license text.*
### โ
You may
- **Use** and **redistribute** the **unmodified** S-CEReBrO weights (including in commercial settings) **with proper attribution** to the S-CEReBrO authors.
- **Fine-tune / adapt** the weights **for your internal use** (research or production) **without redistributing** the modified weights.
- **Publish your code, configs, logs, and papers** describing experiments with S-CEReBrO (please cite the paper).
### ๐ซ You may not
- **Share, host, or redistribute any modified weights** (including LoRA/adapter/delta checkpoints or pruned/quantized variants). Any parameter set that encodes an adaptation is considered a derivative and cannot be shared under CC BY-ND 4.0.
- **Imply endorsement** by the S-CEReBrO authors for any derivative or evaluation without our written permission.
- **Use the S-CEReBrO name** in a way that suggests your modified model is an official S-CEReBrO release.
### ๐ค How to contribute improvements (PR-gated releases)
We welcome community improvements via a **pull-request (PR)** workflow. If you believe your improvements should become an **official S-CEReBrO release**:
1. **Open a PR** in the [BioFoundation repository](https://github.com/pulp-bio/biofoundation) describing the change (architecture/head/training recipe, datasets, preprocessing, compute).
2. Include **reproducibility artifacts**: configs, seeds, scripts, environment details, training/validation logs, and the **evaluation protocol** with exact splits.
3. Provide **comprehensive results** (AUROC/AUPR/BA, FLOPs, memory) vs. the baselines reported in the S-CEReBrO paper.
4. After **maintainer review**, approved changes will be **retrained/validated** and, if accepted, **released by the maintainers** as a new **official S-CEReBrO** checkpoint under **CC BY-ND 4.0**.
> Rationale: CC BY-ND protects users from fragmented, lower-quality variants, while still enabling internal fine-tuning and a path for the community to upstream improvements through review.
---
## ๐ Model Summary
- **Goal:** Realize efficient, generalizable, and continuous EEG monitoring while breaking the memory barrier of Transformer-based architectures.
- **Core idea:** **Windowed Alternating Attention** interleaves spatial and temporal attention blocks. This restricts interactions to local neighborhoods in time and space, allowing the model to process long signals while maintaining a constant resident memory. Complexity is $\mathcal{O}(CT)$.
- **Pre-training data:** **>25,000 hours** of EEG from **>12,000 subjects**. Includes TUEG, SEED series, BOAS, SleepEDFx, BCI-NER, and GWD. Downstream subjects (e.g. TUAB) are strictly excluded to prevent leakage.
- **Downstream tasks:** Seizure detection (CHB-MIT, Neonate), Motor Imagery (PhysioNet-MI, SHU-MI), Abnormal classification (TUAB), Mental Workload (STEW), Vigilance Estimation (SEED-VIG), Sleep Staging (ISRUC), Mental Disorder Diagnosis (Mumtaz), Mental Stress (Mental Arithmetic), and Emotion Recognition (SEED-V).
---
## ๐ Model Variants
S-CEReBrO is highly compact, utilizing only 2.4M parameters. This design allows it to achieve state-of-the-art performance with up to 60% fewer parameters than existing foundation models.
---
## ๐ Results
S-CEReBrO achieves state-of-the-art performance on 7 of 11 downstream public benchmarks.
- **CHB-MIT (seizure detection):** 87.45 AUROC.
- **Neonate (seizure detection):** 85.76 AUROC.
- **PhysioNet-MI (motor imagery):** 60.93 Weighted F1.
- **SHU-MI (motor imagery):** 66.48 AUROC.
- **TUAB (abnormal classification):** 89.30 AUROC.
- **STEW (mental workload):** 52.90 Weighted F1.
- **SEED-VIG (vigilance estimation):** 0.93 NRMSE.
- **ISRUC (sleep staging):** 78.23 Weighted F1.
- **Mumtaz (mental disorder diagnosis):** 98.23 AUROC.
- **Mental Arithmetic (mental stress detection):** 68.97 AUROC.
- **SEED-V (emotion recognition):** 28.16 Weighted F1.
**Efficiency & Scaling:** Without low-level optimzations, windowed Alternating Attention can process signals 100x longer than full self-attention (up to 14 hours / 50,000 seconds). It also processes signals 3x longer than low-rank linear attention. Compared to low-rank linear attention on long contexts (15,000 seconds), it requires 55% of the memory while increasing inference throughput by 2.1x.
---
## ๐ง Intended Use & Limitations
**Intended use.** Research on continuous EEG representation learning and classification (clinical diagnostics, BCI, state monitoring) where long context and memory efficiency are necessary.
**Limitations.**
- **Not a medical device.** Do **not** use for clinical decisions without proper validation & regulatory clearance.
- **Unseen topologies:** Zero-shot transfer to **very different/dense** layouts can underperform SOTA despite positive scaling; consider augmenting pre-training montage diversity and spatial encodings.
- **Distribution shifts:** Performance varies across cohorts, devices, and label protocols; validate locally and consider domain adaptation.
---
## ๐๏ธ Architecture & Training
**Spatiotemporal Tokenization.** The raw EEG recording is tokenized using a sliding window. A shared convolutional encoder projects each patch into a latent embedding. Spatiotemporal topology is preserved via an index-based matrix for temporal order and a continuous spatial embedding mapped via an MLP from 3D electrode coordinates.
**Windowed Temporal Attention (WTA).** WTA layers model temporal dependencies independently for each channel. Each query attends only to keys within a local neighborhood, avoiding memory accumulation.
**Windowed Spatial Attention (WSA).** WSA layers facilitate cross-channel information exchange at a fixed time index. Attention computation is restricted to a local neighborhood. Layer-specific dilation and shift factors stagger receptive fields to enable distant, physiologically related channels to interact.
**Pre-training objectives.** The model is pre-trained using Masked Autoencoding (MAE). The objective minimizes the weighted sum of reconstruction losses for masked and visible patch positions.
---
## ๐ง How to Use
S-CEReBrO is supported within the BioFoundation framework. Experiments and setups follow similar pipeline structures:
1. **Install & read data prep**: clone the [BioFoundation repo](https://github.com/pulp-bio/biofoundation). Set up the environment as described there, then open `make_datasets/README.md` for dataset-specific notes.
2. **Point to weights**: set `pretrained_safetensors_path` to the downloaded weights in your experiment YAML.
3. **Preprocess data**: acquire fine-tuning dataset and follow preprocessing protocol to generate `train/test/val.lmdb` files.
4. **Update data module config**
5. **Task settings**: Configure `classification_type`, `model.num_classes`, and task modes inside your YAML config based on downstream objectives.
6. **Launch fine-tuning (Hydra)**:
```bash
python -u run_train.py +experiment=s_cerebro_finetune
```
---
## ๐ Sources
- **Code:** https://github.com/pulp-bio/BioFoundation
- **Paper:** S-CEReBrO: Breaking the Memory Barrier in Continuous EEG Monitoring (arxiv:2607.27913)
---
## ๐ Citation
If you use S-CEReBrO, please cite:
```bibtex
@misc{bucagu2026scerebrobreakingmemorybarrier,
title={S-CEReBrO: Breaking the Memory Barrier in Continuous EEG Monitoring},
author={Glenn Anta Bucagu and Thorir Mar Ingolfsson and Yawei Li and Luca Benini},
year={2026},
eprint={2607.27913},
archivePrefix={arXiv},
primaryClass={cs.LG},
url={https://arxiv.org/abs/2607.27913},
}
```
---
## ๐ ๏ธ Maintenance & Contact
- **Issues & support:** please open a GitHub issue in the BioFoundation repository.
---
## ๐ Related Models
- **[LUNA](https://huggingface.co/PulpBio/LUNA)** โ Transformer-based topology-agnostic EEG foundation model (NeurIPS 2025). Source of the channel-unification cross-attention module that LuMamba reuses.
- **[FEMBA](https://huggingface.co/PulpBio/FEMBA)** โ Bidirectional Mamba foundation model for EEG. Source of the linear-complexity temporal backbone that LuMamba reuses.
- **[TinyMyo](https://huggingface.co/PulpBio/TinyMyo)** โ Tiny foundation model for flexible EMG signal processing at the edge.
## ๐๏ธ Changelog
- **v1.0:** Initial release of LuMamba model card with task-specific checkpoints and instructions.