fastapi
uvicorn
slowapi
redis
httpx
aiohttp
biopython
litellm
sentry-sdk
python-dotenv
supabase
reportlab
pydantic[email]
rdkit
numpy
openmm>=8.0  # OpenMM is on PyPI since 8.0 (pip-installable in Dockerfile and Render)
# openbabel-wheel  # removed — SMILES→3D via NCI CACTUS API, Vina reads PDB/SDF natively
# primer3-py>=2.0.3  (optional — requires C compiler; installed separately in Dockerfile)

# dev / testing
pytest>=7.0
httpx>=0.24