Upload metadata (20260122-191704)
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releases/20260122-191704/meta.json
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| 1 |
+
{
|
| 2 |
+
"framework": "ExplainML Studio",
|
| 3 |
+
"model": "Logistic Regression",
|
| 4 |
+
"created_at_utc": "2026-01-22T19:16:44.520131",
|
| 5 |
+
"schema": {
|
| 6 |
+
"features": [
|
| 7 |
+
"Age (years) ",
|
| 8 |
+
"Gender",
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| 9 |
+
"Ethnicity ",
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| 10 |
+
"Type of Leukemia ",
|
| 11 |
+
"ECOG ",
|
| 12 |
+
"Risk Assesment",
|
| 13 |
+
"WBCs on Admission\n ( x10^9/L) ",
|
| 14 |
+
"Hb on Admission (g/L)",
|
| 15 |
+
"LDH on Admission (IU/L) ",
|
| 16 |
+
"CNS Involvement ",
|
| 17 |
+
"MDx Leukemia Screen 1",
|
| 18 |
+
"MDx Leukemia Screen 2",
|
| 19 |
+
"Pre-Induction bone marrow biopsy blasts %",
|
| 20 |
+
"Date of 1st Bone Marrow biopsy (Date of Diagnosis) ",
|
| 21 |
+
"Post-Induction MRD ",
|
| 22 |
+
"Date of 1st CR",
|
| 23 |
+
"Induction ",
|
| 24 |
+
"CD1a",
|
| 25 |
+
"CD2",
|
| 26 |
+
"CD3",
|
| 27 |
+
"CD4",
|
| 28 |
+
"CD5",
|
| 29 |
+
"CD7",
|
| 30 |
+
"CD8",
|
| 31 |
+
"CD9",
|
| 32 |
+
"CD10",
|
| 33 |
+
"CD11b",
|
| 34 |
+
"CD11c",
|
| 35 |
+
"CD13",
|
| 36 |
+
"CD14",
|
| 37 |
+
"CD15",
|
| 38 |
+
"CD16",
|
| 39 |
+
"CD19",
|
| 40 |
+
"CD20",
|
| 41 |
+
"CD21",
|
| 42 |
+
"CD22",
|
| 43 |
+
"CD23",
|
| 44 |
+
"CD24",
|
| 45 |
+
"CD25",
|
| 46 |
+
"CD30",
|
| 47 |
+
"CD33",
|
| 48 |
+
"CD34",
|
| 49 |
+
"CD35",
|
| 50 |
+
"CD36",
|
| 51 |
+
"CD38",
|
| 52 |
+
"CD41",
|
| 53 |
+
"CD41a",
|
| 54 |
+
"CD42a",
|
| 55 |
+
"CD42b",
|
| 56 |
+
"CD43",
|
| 57 |
+
"CD45",
|
| 58 |
+
"CD56",
|
| 59 |
+
"CD57",
|
| 60 |
+
"CD58",
|
| 61 |
+
"CD61",
|
| 62 |
+
"CD64",
|
| 63 |
+
"CD66",
|
| 64 |
+
"CD66c",
|
| 65 |
+
"CD71",
|
| 66 |
+
"CD73",
|
| 67 |
+
"CD79",
|
| 68 |
+
"CD79a",
|
| 69 |
+
"CD81",
|
| 70 |
+
"CD99",
|
| 71 |
+
"CD103",
|
| 72 |
+
"CD105",
|
| 73 |
+
"CD117",
|
| 74 |
+
"CD123",
|
| 75 |
+
"CD138",
|
| 76 |
+
"CD163",
|
| 77 |
+
"CD200",
|
| 78 |
+
"CD300e",
|
| 79 |
+
"CD304",
|
| 80 |
+
"cCD3",
|
| 81 |
+
"cCD22",
|
| 82 |
+
"cCD79a",
|
| 83 |
+
"sCD3",
|
| 84 |
+
"icCD3",
|
| 85 |
+
"icCD22",
|
| 86 |
+
"icCD79a",
|
| 87 |
+
"cyCD3",
|
| 88 |
+
"cyCD22",
|
| 89 |
+
"cyCD79a",
|
| 90 |
+
"HLA-DR",
|
| 91 |
+
"MPO",
|
| 92 |
+
"TdT",
|
| 93 |
+
"kappa",
|
| 94 |
+
"lambda",
|
| 95 |
+
"cp_sepsis",
|
| 96 |
+
"cp_thrombocytopenia",
|
| 97 |
+
"cp_bleeding",
|
| 98 |
+
"cp_bsymptoms",
|
| 99 |
+
"cp_lymphadenopathy",
|
| 100 |
+
"cp_cns",
|
| 101 |
+
"cp_severity_score",
|
| 102 |
+
"emi_yes_unspecified",
|
| 103 |
+
"emi_severity_score",
|
| 104 |
+
"fish_normal",
|
| 105 |
+
"fish_inv16_cbfb_myh11",
|
| 106 |
+
"fish_t821_runx1_runx1t1",
|
| 107 |
+
"fish_t1517_pml_rara",
|
| 108 |
+
"fish_kmt2a_mll_11q23",
|
| 109 |
+
"fish_bcr_abl1_t922",
|
| 110 |
+
"fish_etv6_runx1_t1221",
|
| 111 |
+
"fish_tcf3_pbx1_t119",
|
| 112 |
+
"fish_igh_14q32_rearr",
|
| 113 |
+
"fish_myc_8q24",
|
| 114 |
+
"fish_crlf2_rearr",
|
| 115 |
+
"fish_nup214_9q34",
|
| 116 |
+
"fish_cdkn2a_9p21_del",
|
| 117 |
+
"fish_trisomy8",
|
| 118 |
+
"fish_del5q_monosomy5",
|
| 119 |
+
"fish_del7q_monosomy7",
|
| 120 |
+
"fish_tp53_del17p",
|
| 121 |
+
"fish_trisomy12",
|
| 122 |
+
"fish_del13q",
|
| 123 |
+
"fish_del11q",
|
| 124 |
+
"fish_missing",
|
| 125 |
+
"fish_any_abnormal",
|
| 126 |
+
"fish_abnormality_count",
|
| 127 |
+
"ngs_no_mutation",
|
| 128 |
+
"ngs_flt3_itd",
|
| 129 |
+
"ngs_flt3_tkd",
|
| 130 |
+
"ngs_npm1",
|
| 131 |
+
"ngs_cebpa",
|
| 132 |
+
"ngs_dnmt3a",
|
| 133 |
+
"ngs_idh1",
|
| 134 |
+
"ngs_idh2",
|
| 135 |
+
"ngs_tet2",
|
| 136 |
+
"ngs_asxl1",
|
| 137 |
+
"ngs_tp53",
|
| 138 |
+
"ngs_runx1",
|
| 139 |
+
"ngs_kit",
|
| 140 |
+
"ngs_ezh2",
|
| 141 |
+
"ngs_spliceosome",
|
| 142 |
+
"ngs_ikzf1",
|
| 143 |
+
"ngs_notch1",
|
| 144 |
+
"ngs_phf6",
|
| 145 |
+
"ngs_jak2",
|
| 146 |
+
"ngs_crlf2",
|
| 147 |
+
"ngs_calr",
|
| 148 |
+
"ngs_mpl",
|
| 149 |
+
"ngs_setbp1",
|
| 150 |
+
"ngs_any_mutation",
|
| 151 |
+
"ngs_mutation_count"
|
| 152 |
+
],
|
| 153 |
+
"numeric": [
|
| 154 |
+
"Age (years) ",
|
| 155 |
+
"ECOG ",
|
| 156 |
+
"WBCs on Admission\n ( x10^9/L) ",
|
| 157 |
+
"Hb on Admission (g/L)",
|
| 158 |
+
"LDH on Admission (IU/L) ",
|
| 159 |
+
"MDx Leukemia Screen 1",
|
| 160 |
+
"Pre-Induction bone marrow biopsy blasts %",
|
| 161 |
+
"Date of 1st Bone Marrow biopsy (Date of Diagnosis) ",
|
| 162 |
+
"Date of 1st CR"
|
| 163 |
+
],
|
| 164 |
+
"categorical": [
|
| 165 |
+
"Gender",
|
| 166 |
+
"Ethnicity ",
|
| 167 |
+
"Type of Leukemia ",
|
| 168 |
+
"Risk Assesment",
|
| 169 |
+
"CNS Involvement ",
|
| 170 |
+
"MDx Leukemia Screen 2",
|
| 171 |
+
"Post-Induction MRD ",
|
| 172 |
+
"Induction ",
|
| 173 |
+
"CD1a",
|
| 174 |
+
"CD2",
|
| 175 |
+
"CD3",
|
| 176 |
+
"CD4",
|
| 177 |
+
"CD5",
|
| 178 |
+
"CD7",
|
| 179 |
+
"CD8",
|
| 180 |
+
"CD9",
|
| 181 |
+
"CD10",
|
| 182 |
+
"CD11b",
|
| 183 |
+
"CD11c",
|
| 184 |
+
"CD13",
|
| 185 |
+
"CD14",
|
| 186 |
+
"CD15",
|
| 187 |
+
"CD16",
|
| 188 |
+
"CD19",
|
| 189 |
+
"CD20",
|
| 190 |
+
"CD21",
|
| 191 |
+
"CD22",
|
| 192 |
+
"CD23",
|
| 193 |
+
"CD24",
|
| 194 |
+
"CD25",
|
| 195 |
+
"CD30",
|
| 196 |
+
"CD33",
|
| 197 |
+
"CD34",
|
| 198 |
+
"CD35",
|
| 199 |
+
"CD36",
|
| 200 |
+
"CD38",
|
| 201 |
+
"CD41",
|
| 202 |
+
"CD41a",
|
| 203 |
+
"CD42a",
|
| 204 |
+
"CD42b",
|
| 205 |
+
"CD43",
|
| 206 |
+
"CD45",
|
| 207 |
+
"CD56",
|
| 208 |
+
"CD57",
|
| 209 |
+
"CD58",
|
| 210 |
+
"CD61",
|
| 211 |
+
"CD64",
|
| 212 |
+
"CD66",
|
| 213 |
+
"CD66c",
|
| 214 |
+
"CD71",
|
| 215 |
+
"CD73",
|
| 216 |
+
"CD79",
|
| 217 |
+
"CD79a",
|
| 218 |
+
"CD81",
|
| 219 |
+
"CD99",
|
| 220 |
+
"CD103",
|
| 221 |
+
"CD105",
|
| 222 |
+
"CD117",
|
| 223 |
+
"CD123",
|
| 224 |
+
"CD138",
|
| 225 |
+
"CD163",
|
| 226 |
+
"CD200",
|
| 227 |
+
"CD300e",
|
| 228 |
+
"CD304",
|
| 229 |
+
"cCD3",
|
| 230 |
+
"cCD22",
|
| 231 |
+
"cCD79a",
|
| 232 |
+
"sCD3",
|
| 233 |
+
"icCD3",
|
| 234 |
+
"icCD22",
|
| 235 |
+
"icCD79a",
|
| 236 |
+
"cyCD3",
|
| 237 |
+
"cyCD22",
|
| 238 |
+
"cyCD79a",
|
| 239 |
+
"HLA-DR",
|
| 240 |
+
"MPO",
|
| 241 |
+
"TdT",
|
| 242 |
+
"kappa",
|
| 243 |
+
"lambda",
|
| 244 |
+
"cp_sepsis",
|
| 245 |
+
"cp_thrombocytopenia",
|
| 246 |
+
"cp_bleeding",
|
| 247 |
+
"cp_bsymptoms",
|
| 248 |
+
"cp_lymphadenopathy",
|
| 249 |
+
"cp_cns",
|
| 250 |
+
"cp_severity_score",
|
| 251 |
+
"emi_yes_unspecified",
|
| 252 |
+
"emi_severity_score",
|
| 253 |
+
"fish_normal",
|
| 254 |
+
"fish_inv16_cbfb_myh11",
|
| 255 |
+
"fish_t821_runx1_runx1t1",
|
| 256 |
+
"fish_t1517_pml_rara",
|
| 257 |
+
"fish_kmt2a_mll_11q23",
|
| 258 |
+
"fish_bcr_abl1_t922",
|
| 259 |
+
"fish_etv6_runx1_t1221",
|
| 260 |
+
"fish_tcf3_pbx1_t119",
|
| 261 |
+
"fish_igh_14q32_rearr",
|
| 262 |
+
"fish_myc_8q24",
|
| 263 |
+
"fish_crlf2_rearr",
|
| 264 |
+
"fish_nup214_9q34",
|
| 265 |
+
"fish_cdkn2a_9p21_del",
|
| 266 |
+
"fish_trisomy8",
|
| 267 |
+
"fish_del5q_monosomy5",
|
| 268 |
+
"fish_del7q_monosomy7",
|
| 269 |
+
"fish_tp53_del17p",
|
| 270 |
+
"fish_trisomy12",
|
| 271 |
+
"fish_del13q",
|
| 272 |
+
"fish_del11q",
|
| 273 |
+
"fish_missing",
|
| 274 |
+
"fish_any_abnormal",
|
| 275 |
+
"fish_abnormality_count",
|
| 276 |
+
"ngs_no_mutation",
|
| 277 |
+
"ngs_flt3_itd",
|
| 278 |
+
"ngs_flt3_tkd",
|
| 279 |
+
"ngs_npm1",
|
| 280 |
+
"ngs_cebpa",
|
| 281 |
+
"ngs_dnmt3a",
|
| 282 |
+
"ngs_idh1",
|
| 283 |
+
"ngs_idh2",
|
| 284 |
+
"ngs_tet2",
|
| 285 |
+
"ngs_asxl1",
|
| 286 |
+
"ngs_tp53",
|
| 287 |
+
"ngs_runx1",
|
| 288 |
+
"ngs_kit",
|
| 289 |
+
"ngs_ezh2",
|
| 290 |
+
"ngs_spliceosome",
|
| 291 |
+
"ngs_ikzf1",
|
| 292 |
+
"ngs_notch1",
|
| 293 |
+
"ngs_phf6",
|
| 294 |
+
"ngs_jak2",
|
| 295 |
+
"ngs_crlf2",
|
| 296 |
+
"ngs_calr",
|
| 297 |
+
"ngs_mpl",
|
| 298 |
+
"ngs_setbp1",
|
| 299 |
+
"ngs_any_mutation",
|
| 300 |
+
"ngs_mutation_count"
|
| 301 |
+
],
|
| 302 |
+
"label": "AA"
|
| 303 |
+
},
|
| 304 |
+
"feature_reduction": {
|
| 305 |
+
"variance_threshold": 0.0,
|
| 306 |
+
"use_dimred": false,
|
| 307 |
+
"svd_components": null,
|
| 308 |
+
"use_feature_selection": true,
|
| 309 |
+
"l1_C": 1.0,
|
| 310 |
+
"selection_method": "SelectFromModel(L1 saga, threshold=mean)",
|
| 311 |
+
"note": "If SVD is enabled, SHAP becomes component-level (less interpretable)."
|
| 312 |
+
},
|
| 313 |
+
"positive_class": "YES",
|
| 314 |
+
"metrics": {
|
| 315 |
+
"roc_auc": 0.5222222222222223,
|
| 316 |
+
"n_train": 91,
|
| 317 |
+
"n_test": 23,
|
| 318 |
+
"threshold@0.5": 0.5,
|
| 319 |
+
"accuracy@0.5": 0.8260869565217391,
|
| 320 |
+
"balanced_accuracy@0.5": 0.6,
|
| 321 |
+
"precision@0.5": 1.0,
|
| 322 |
+
"recall@0.5": 0.2,
|
| 323 |
+
"f1@0.5": 0.3333333333333333,
|
| 324 |
+
"sensitivity@0.5": 0.2,
|
| 325 |
+
"specificity@0.5": 1.0,
|
| 326 |
+
"confusion_matrix@0.5": {
|
| 327 |
+
"tn": 18,
|
| 328 |
+
"fp": 0,
|
| 329 |
+
"fn": 4,
|
| 330 |
+
"tp": 1
|
| 331 |
+
},
|
| 332 |
+
"roc_curve": {
|
| 333 |
+
"fpr": [
|
| 334 |
+
0.0,
|
| 335 |
+
0.0,
|
| 336 |
+
0.3888888888888889,
|
| 337 |
+
0.3888888888888889,
|
| 338 |
+
0.7222222222222222,
|
| 339 |
+
0.7222222222222222,
|
| 340 |
+
0.8888888888888888,
|
| 341 |
+
0.8888888888888888,
|
| 342 |
+
1.0
|
| 343 |
+
],
|
| 344 |
+
"tpr": [
|
| 345 |
+
0.0,
|
| 346 |
+
0.2,
|
| 347 |
+
0.2,
|
| 348 |
+
0.6,
|
| 349 |
+
0.6,
|
| 350 |
+
0.8,
|
| 351 |
+
0.8,
|
| 352 |
+
1.0,
|
| 353 |
+
1.0
|
| 354 |
+
],
|
| 355 |
+
"thresholds": [
|
| 356 |
+
Infinity,
|
| 357 |
+
0.9865817327189806,
|
| 358 |
+
0.09846290267783717,
|
| 359 |
+
0.08514684665413702,
|
| 360 |
+
0.057944324116905685,
|
| 361 |
+
0.045589174036013695,
|
| 362 |
+
0.023193993957220663,
|
| 363 |
+
0.019386468528840253,
|
| 364 |
+
0.010119968122079733
|
| 365 |
+
]
|
| 366 |
+
},
|
| 367 |
+
"pr_curve": {
|
| 368 |
+
"average_precision": 0.39912231559290384,
|
| 369 |
+
"precision": [
|
| 370 |
+
0.21739130434782608,
|
| 371 |
+
0.22727272727272727,
|
| 372 |
+
0.23809523809523808,
|
| 373 |
+
0.2,
|
| 374 |
+
0.21052631578947367,
|
| 375 |
+
0.2222222222222222,
|
| 376 |
+
0.23529411764705882,
|
| 377 |
+
0.1875,
|
| 378 |
+
0.2,
|
| 379 |
+
0.21428571428571427,
|
| 380 |
+
0.23076923076923078,
|
| 381 |
+
0.25,
|
| 382 |
+
0.2727272727272727,
|
| 383 |
+
0.3,
|
| 384 |
+
0.2222222222222222,
|
| 385 |
+
0.125,
|
| 386 |
+
0.14285714285714285,
|
| 387 |
+
0.16666666666666666,
|
| 388 |
+
0.2,
|
| 389 |
+
0.25,
|
| 390 |
+
0.3333333333333333,
|
| 391 |
+
0.5,
|
| 392 |
+
1.0,
|
| 393 |
+
1.0
|
| 394 |
+
],
|
| 395 |
+
"recall": [
|
| 396 |
+
1.0,
|
| 397 |
+
1.0,
|
| 398 |
+
1.0,
|
| 399 |
+
0.8,
|
| 400 |
+
0.8,
|
| 401 |
+
0.8,
|
| 402 |
+
0.8,
|
| 403 |
+
0.6,
|
| 404 |
+
0.6,
|
| 405 |
+
0.6,
|
| 406 |
+
0.6,
|
| 407 |
+
0.6,
|
| 408 |
+
0.6,
|
| 409 |
+
0.6,
|
| 410 |
+
0.4,
|
| 411 |
+
0.2,
|
| 412 |
+
0.2,
|
| 413 |
+
0.2,
|
| 414 |
+
0.2,
|
| 415 |
+
0.2,
|
| 416 |
+
0.2,
|
| 417 |
+
0.2,
|
| 418 |
+
0.2,
|
| 419 |
+
0.0
|
| 420 |
+
],
|
| 421 |
+
"thresholds": [
|
| 422 |
+
0.010119968122079733,
|
| 423 |
+
0.01173159936946051,
|
| 424 |
+
0.019386468528840253,
|
| 425 |
+
0.023193993957220663,
|
| 426 |
+
0.035102610588809285,
|
| 427 |
+
0.03926799101643958,
|
| 428 |
+
0.045589174036013695,
|
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}
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}
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}
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