Synav commited on
Commit
5536e1c
·
verified ·
1 Parent(s): 55291a3

Upload metadata (20260123-080905)

Browse files
Files changed (1) hide show
  1. releases/20260123-080905/meta.json +439 -0
releases/20260123-080905/meta.json ADDED
@@ -0,0 +1,439 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ {
2
+ "framework": "ExplainML Studio",
3
+ "model": "Logistic Regression",
4
+ "created_at_utc": "2026-01-23T08:08:03.265081",
5
+ "schema": {
6
+ "features": [
7
+ "Age (years) ",
8
+ "Gender",
9
+ "Ethnicity ",
10
+ "Type of Leukemia ",
11
+ "ECOG ",
12
+ "Risk Assesment",
13
+ "WBCs on Admission\n ( x10^9/L) ",
14
+ "Hb on Admission (g/L)",
15
+ "LDH on Admission (IU/L) ",
16
+ "CNS Involvement ",
17
+ "MDx Leukemia Screen 1",
18
+ "MDx Leukemia Screen 2",
19
+ "Pre-Induction bone marrow biopsy blasts %",
20
+ "Date of 1st Bone Marrow biopsy (Date of Diagnosis) ",
21
+ "Post-Induction MRD ",
22
+ "Date of 1st CR",
23
+ "Induction ",
24
+ "cp_sepsis",
25
+ "cp_thrombocytopenia",
26
+ "cp_bleeding",
27
+ "cp_bsymptoms",
28
+ "cp_lymphadenopathy",
29
+ "cp_cns",
30
+ "cp_severity_score",
31
+ "emi_yes_unspecified",
32
+ "emi_severity_score",
33
+ "fish_normal",
34
+ "fish_inv16_cbfb_myh11",
35
+ "fish_t821_runx1_runx1t1",
36
+ "fish_t1517_pml_rara",
37
+ "fish_kmt2a_mll_11q23",
38
+ "fish_bcr_abl1_t922",
39
+ "fish_etv6_runx1_t1221",
40
+ "fish_tcf3_pbx1_t119",
41
+ "fish_igh_14q32_rearr",
42
+ "fish_myc_8q24",
43
+ "fish_crlf2_rearr",
44
+ "fish_nup214_9q34",
45
+ "fish_cdkn2a_9p21_del",
46
+ "fish_trisomy8",
47
+ "fish_del5q_monosomy5",
48
+ "fish_del7q_monosomy7",
49
+ "fish_tp53_del17p",
50
+ "fish_trisomy12",
51
+ "fish_del13q",
52
+ "fish_del11q",
53
+ "fish_missing",
54
+ "fish_any_abnormal",
55
+ "fish_abnormality_count",
56
+ "ngs_no_mutation",
57
+ "ngs_flt3_itd",
58
+ "ngs_flt3_tkd",
59
+ "ngs_npm1",
60
+ "ngs_cebpa",
61
+ "ngs_dnmt3a",
62
+ "ngs_idh1",
63
+ "ngs_idh2",
64
+ "ngs_tet2",
65
+ "ngs_asxl1",
66
+ "ngs_tp53",
67
+ "ngs_runx1",
68
+ "ngs_kit",
69
+ "ngs_ezh2",
70
+ "ngs_spliceosome",
71
+ "ngs_ikzf1",
72
+ "ngs_notch1",
73
+ "ngs_phf6",
74
+ "ngs_jak2",
75
+ "ngs_crlf2",
76
+ "ngs_calr",
77
+ "ngs_mpl",
78
+ "ngs_setbp1",
79
+ "ngs_any_mutation",
80
+ "ngs_mutation_count"
81
+ ],
82
+ "numeric": [
83
+ "Age (years) ",
84
+ "ECOG ",
85
+ "WBCs on Admission\n ( x10^9/L) ",
86
+ "Hb on Admission (g/L)",
87
+ "LDH on Admission (IU/L) ",
88
+ "MDx Leukemia Screen 1",
89
+ "Pre-Induction bone marrow biopsy blasts %",
90
+ "Date of 1st Bone Marrow biopsy (Date of Diagnosis) ",
91
+ "Date of 1st CR",
92
+ "cp_severity_score",
93
+ "emi_severity_score",
94
+ "fish_abnormality_count",
95
+ "ngs_mutation_count"
96
+ ],
97
+ "categorical": [
98
+ "Gender",
99
+ "Ethnicity ",
100
+ "Type of Leukemia ",
101
+ "Risk Assesment",
102
+ "CNS Involvement ",
103
+ "MDx Leukemia Screen 2",
104
+ "Post-Induction MRD ",
105
+ "Induction ",
106
+ "cp_sepsis",
107
+ "cp_thrombocytopenia",
108
+ "cp_bleeding",
109
+ "cp_bsymptoms",
110
+ "cp_lymphadenopathy",
111
+ "cp_cns",
112
+ "emi_yes_unspecified",
113
+ "fish_normal",
114
+ "fish_inv16_cbfb_myh11",
115
+ "fish_t821_runx1_runx1t1",
116
+ "fish_t1517_pml_rara",
117
+ "fish_kmt2a_mll_11q23",
118
+ "fish_bcr_abl1_t922",
119
+ "fish_etv6_runx1_t1221",
120
+ "fish_tcf3_pbx1_t119",
121
+ "fish_igh_14q32_rearr",
122
+ "fish_myc_8q24",
123
+ "fish_crlf2_rearr",
124
+ "fish_nup214_9q34",
125
+ "fish_cdkn2a_9p21_del",
126
+ "fish_trisomy8",
127
+ "fish_del5q_monosomy5",
128
+ "fish_del7q_monosomy7",
129
+ "fish_tp53_del17p",
130
+ "fish_trisomy12",
131
+ "fish_del13q",
132
+ "fish_del11q",
133
+ "fish_missing",
134
+ "fish_any_abnormal",
135
+ "ngs_no_mutation",
136
+ "ngs_flt3_itd",
137
+ "ngs_flt3_tkd",
138
+ "ngs_npm1",
139
+ "ngs_cebpa",
140
+ "ngs_dnmt3a",
141
+ "ngs_idh1",
142
+ "ngs_idh2",
143
+ "ngs_tet2",
144
+ "ngs_asxl1",
145
+ "ngs_tp53",
146
+ "ngs_runx1",
147
+ "ngs_kit",
148
+ "ngs_ezh2",
149
+ "ngs_spliceosome",
150
+ "ngs_ikzf1",
151
+ "ngs_notch1",
152
+ "ngs_phf6",
153
+ "ngs_jak2",
154
+ "ngs_crlf2",
155
+ "ngs_calr",
156
+ "ngs_mpl",
157
+ "ngs_setbp1",
158
+ "ngs_any_mutation"
159
+ ],
160
+ "label": "AA"
161
+ },
162
+ "feature_reduction": {
163
+ "variance_threshold": 0.0,
164
+ "use_dimred": false,
165
+ "svd_components": null,
166
+ "use_feature_selection": true,
167
+ "l1_C": 2.02,
168
+ "selection_method": "SelectFromModel(L1 saga, threshold=mean)",
169
+ "note": "If SVD is enabled, SHAP becomes component-level (less interpretable)."
170
+ },
171
+ "positive_class": "YES",
172
+ "metrics": {
173
+ "roc_auc": 0.7777777777777778,
174
+ "n_train": 91,
175
+ "n_test": 23,
176
+ "threshold@0.5": 0.5,
177
+ "accuracy@0.5": 0.8260869565217391,
178
+ "balanced_accuracy@0.5": 0.6,
179
+ "precision@0.5": 1.0,
180
+ "recall@0.5": 0.2,
181
+ "f1@0.5": 0.3333333333333333,
182
+ "sensitivity@0.5": 0.2,
183
+ "specificity@0.5": 1.0,
184
+ "confusion_matrix@0.5": {
185
+ "tn": 18,
186
+ "fp": 0,
187
+ "fn": 4,
188
+ "tp": 1
189
+ },
190
+ "roc_curve": {
191
+ "fpr": [
192
+ 0.0,
193
+ 0.0,
194
+ 0.0,
195
+ 0.05555555555555555,
196
+ 0.05555555555555555,
197
+ 0.2222222222222222,
198
+ 0.2222222222222222,
199
+ 0.8333333333333334,
200
+ 0.8333333333333334,
201
+ 1.0
202
+ ],
203
+ "tpr": [
204
+ 0.0,
205
+ 0.2,
206
+ 0.4,
207
+ 0.4,
208
+ 0.6,
209
+ 0.6,
210
+ 0.8,
211
+ 0.8,
212
+ 1.0,
213
+ 1.0
214
+ ],
215
+ "thresholds": [
216
+ Infinity,
217
+ 0.9401927685412899,
218
+ 0.387853510786871,
219
+ 0.33520087601844484,
220
+ 0.25521942909324935,
221
+ 0.13120678747521125,
222
+ 0.11832073683908892,
223
+ 0.03182832115145727,
224
+ 0.02029902610839585,
225
+ 0.005448761903227496
226
+ ]
227
+ },
228
+ "pr_curve": {
229
+ "average_precision": 0.7,
230
+ "precision": [
231
+ 0.21739130434782608,
232
+ 0.22727272727272727,
233
+ 0.23809523809523808,
234
+ 0.25,
235
+ 0.21052631578947367,
236
+ 0.2222222222222222,
237
+ 0.23529411764705882,
238
+ 0.25,
239
+ 0.26666666666666666,
240
+ 0.2857142857142857,
241
+ 0.3076923076923077,
242
+ 0.3333333333333333,
243
+ 0.36363636363636365,
244
+ 0.4,
245
+ 0.4444444444444444,
246
+ 0.5,
247
+ 0.42857142857142855,
248
+ 0.5,
249
+ 0.6,
250
+ 0.75,
251
+ 0.6666666666666666,
252
+ 1.0,
253
+ 1.0,
254
+ 1.0
255
+ ],
256
+ "recall": [
257
+ 1.0,
258
+ 1.0,
259
+ 1.0,
260
+ 1.0,
261
+ 0.8,
262
+ 0.8,
263
+ 0.8,
264
+ 0.8,
265
+ 0.8,
266
+ 0.8,
267
+ 0.8,
268
+ 0.8,
269
+ 0.8,
270
+ 0.8,
271
+ 0.8,
272
+ 0.8,
273
+ 0.6,
274
+ 0.6,
275
+ 0.6,
276
+ 0.6,
277
+ 0.4,
278
+ 0.4,
279
+ 0.2,
280
+ 0.0
281
+ ],
282
+ "thresholds": [
283
+ 0.005448761903227496,
284
+ 0.008499754519461278,
285
+ 0.01700371592701681,
286
+ 0.02029902610839585,
287
+ 0.03182832115145727,
288
+ 0.03679260679937329,
289
+ 0.037681526592555054,
290
+ 0.044135481672915214,
291
+ 0.04907957991234545,
292
+ 0.04919995468476145,
293
+ 0.05549010588060292,
294
+ 0.08858654882714237,
295
+ 0.10126818841287648,
296
+ 0.10502022660327305,
297
+ 0.10822372270290433,
298
+ 0.11832073683908892,
299
+ 0.13120678747521125,
300
+ 0.16868370438358013,
301
+ 0.17229511530516792,
302
+ 0.25521942909324935,
303
+ 0.33520087601844484,
304
+ 0.387853510786871,
305
+ 0.9401927685412899
306
+ ]
307
+ },
308
+ "calibration": {
309
+ "n_bins": 5,
310
+ "strategy": "quantile",
311
+ "prob_true": [
312
+ 0.2,
313
+ 0.0,
314
+ 0.0,
315
+ 0.25,
316
+ 0.6
317
+ ],
318
+ "prob_pred": [
319
+ 0.01661591592191174,
320
+ 0.04192229874429725,
321
+ 0.07991300488173125,
322
+ 0.13160873785019617,
323
+ 0.4181523399490046
324
+ ],
325
+ "brier": 0.12664191179189
326
+ },
327
+ "decision_curve": {
328
+ "thresholds": [
329
+ 0.01,
330
+ 0.050833333333333335,
331
+ 0.09166666666666666,
332
+ 0.1325,
333
+ 0.17333333333333334,
334
+ 0.21416666666666667,
335
+ 0.255,
336
+ 0.29583333333333334,
337
+ 0.33666666666666667,
338
+ 0.3775,
339
+ 0.41833333333333333,
340
+ 0.45916666666666667,
341
+ 0.5,
342
+ 0.5408333333333333,
343
+ 0.5816666666666667,
344
+ 0.6225,
345
+ 0.6633333333333333,
346
+ 0.7041666666666666,
347
+ 0.745,
348
+ 0.7858333333333334,
349
+ 0.8266666666666667,
350
+ 0.8674999999999999,
351
+ 0.9083333333333333,
352
+ 0.9491666666666667,
353
+ 0.99
354
+ ],
355
+ "net_benefit_model": [
356
+ 0.2103645147123408,
357
+ 0.1529564453945108,
358
+ 0.1431990426804946,
359
+ 0.11051246710938478,
360
+ 0.12131837307152875,
361
+ 0.11858545806630089,
362
+ 0.11555296177414648,
363
+ 0.06869050681759711,
364
+ 0.08695652173913043,
365
+ 0.08695652173913043,
366
+ 0.043478260869565216,
367
+ 0.043478260869565216,
368
+ 0.043478260869565216,
369
+ 0.043478260869565216,
370
+ 0.043478260869565216,
371
+ 0.043478260869565216,
372
+ 0.043478260869565216,
373
+ 0.043478260869565216,
374
+ 0.043478260869565216,
375
+ 0.043478260869565216,
376
+ 0.043478260869565216,
377
+ 0.043478260869565216,
378
+ 0.043478260869565216,
379
+ 0.0,
380
+ 0.0
381
+ ],
382
+ "net_benefit_all": [
383
+ 0.20948616600790512,
384
+ 0.175478108180326,
385
+ 0.13841244515356999,
386
+ 0.09785741135196088,
387
+ 0.05329593267882185,
388
+ 0.004103462584720358,
389
+ -0.050481470674058976,
390
+ -0.11139696423977366,
391
+ -0.17981210399825212,
392
+ -0.25720272393923527,
393
+ -0.3454590756197833,
394
+ -0.4470422723923094,
395
+ -0.5652173913043479,
396
+ -0.7044109524185275,
397
+ -0.8707777585310931,
398
+ -1.073135617621653,
399
+ -1.324580284115368,
400
+ -1.6454378444580522,
401
+ -2.0690537084398977,
402
+ -2.6542040263914743,
403
+ -3.5150501672240804,
404
+ -4.906480721903197,
405
+ -7.537549407114624,
406
+ -14.395580898075567,
407
+ -77.26086956521732
408
+ ],
409
+ "net_benefit_none": [
410
+ 0.0,
411
+ 0.0,
412
+ 0.0,
413
+ 0.0,
414
+ 0.0,
415
+ 0.0,
416
+ 0.0,
417
+ 0.0,
418
+ 0.0,
419
+ 0.0,
420
+ 0.0,
421
+ 0.0,
422
+ 0.0,
423
+ 0.0,
424
+ 0.0,
425
+ 0.0,
426
+ 0.0,
427
+ 0.0,
428
+ 0.0,
429
+ 0.0,
430
+ 0.0,
431
+ 0.0,
432
+ 0.0,
433
+ 0.0,
434
+ 0.0
435
+ ],
436
+ "prevalence": 0.21739130434782608
437
+ }
438
+ }
439
+ }