Instructions to use Synthyra/Profluent-E1-150M with libraries, inference providers, notebooks, and local apps. Follow these links to get started.
- Libraries
- Transformers
How to use Synthyra/Profluent-E1-150M with Transformers:
# Use a pipeline as a high-level helper from transformers import pipeline pipe = pipeline("fill-mask", model="Synthyra/Profluent-E1-150M", trust_remote_code=True)# Load model directly from transformers import AutoModelForMaskedLM model = AutoModelForMaskedLM.from_pretrained("Synthyra/Profluent-E1-150M", trust_remote_code=True, device_map="auto") - Notebooks
- Google Colab
- Kaggle
File size: 77,001 Bytes
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[families.esm2]
architecture = "ESM2"
upstreams = ["fair-esm"]
tokenizer_mode = "tokenizer"
public_input = "Amino-acid sequences tokenized to residue IDs"
extra = "core"
reference_container = "reference-esm2"
reference_adapter = "tests.parity.support.reference_adapters.esm2"
attention = ["eager", "sdpa", "flex_attention", "flash_attention_2", "flash_attention_3"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "fp32_parameters_autocast"
precisions = ["default"]
vram_tier = "sequence"
checkpoint_license = "MIT"
hub_license = "mit"
weights_publication_allowed = true
state_transform = "esm2_hf_to_fastplms_v1"
conversion_provenance = "Input: the pinned official ESM2 state dictionary. Transformation: apply the deterministic esm2_hf_to_fastplms_v1 key map while preserving tensor values and materializing the tied input/output embedding values as independent tensors. Output: the pinned Synthyra FastPLMs checkpoint. Validation: release parity compares exact keys and values after the declared non-aliasing transform, tokenizer behavior, and inference. Limitation: any numerical rewrite requires a new transform identifier and exact conversion test."
representative = "esm2_8m"
documentation = "docs/models.md#esm2"
test_tiers = ["check", "compliance", "feature", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/_esm_rotary.py", "models/esm2", "models/ttt.py"]
auto_map = { AutoConfig = "fastplms.models.esm2.modeling_fastesm.FastEsmConfig", AutoModel = "fastplms.models.esm2.modeling_fastesm.FastEsmModel", AutoModelForMaskedLM = "fastplms.models.esm2.modeling_fastesm.FastEsmForMaskedLM", AutoModelForSequenceClassification = "fastplms.models.esm2.modeling_fastesm.FastEsmForSequenceClassification", AutoModelForTokenClassification = "fastplms.models.esm2.modeling_fastesm.FastEsmForTokenClassification" }
[families.esm_plusplus]
architecture = "ESMC"
upstreams = ["biohub-esm", "biohub-transformers"]
tokenizer_mode = "tokenizer"
public_input = "Amino-acid sequences tokenized to residue IDs"
extra = "core"
reference_container = "reference-biohub-esm"
reference_adapter = "tests.parity.support.reference_adapters.esm_plusplus"
attention = ["eager", "sdpa", "flex_attention", "flash_attention_2", "flash_attention_3"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "static_parameters"
precisions = ["default"]
vram_tier = "sequence"
checkpoint_license = "MIT"
hub_license = "mit"
weights_publication_allowed = true
state_transform = "esmc_to_fastplms_v1"
conversion_provenance = "Input: the pinned Biohub ESMC checkpoint. Transformation: apply the deterministic esmc_to_fastplms_v1 parameter map into the FastPLMs ESMC modules. Output: the pinned Synthyra ESMplusplus checkpoint. Validation: release parity compares keys, shapes, dtypes, values, aliases, and live inference. Limitation: runtime attention and precision selection are not serialized weight transforms."
representative = "esmc_small"
documentation = "docs/models.md#esm-and-esmc"
test_tiers = ["check", "compliance", "feature", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/esm_plusplus", "models/ttt.py"]
auto_map = { AutoConfig = "fastplms.models.esm_plusplus.modeling_esm_plusplus.ESMplusplusConfig", AutoModel = "fastplms.models.esm_plusplus.modeling_esm_plusplus.ESMplusplusModel", AutoModelForMaskedLM = "fastplms.models.esm_plusplus.modeling_esm_plusplus.ESMplusplusForMaskedLM" }
[families.esm3]
architecture = "ESM3"
upstreams = ["biohub-esm", "biohub-transformers"]
tokenizer_mode = "tokenizer"
public_input = "Sequence, structure, and function tracks prepared through the multimodal helpers"
extra = "core"
reference_container = "reference-biohub-esm"
reference_adapter = "tests.parity.support.reference_adapters.esm3"
attention = ["eager", "sdpa", "flex_attention"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "fp32_parameters_autocast"
precisions = ["default"]
vram_tier = "large-sequence"
checkpoint_license = "MIT"
hub_license = "mit"
weights_publication_allowed = true
state_transform = "esm3_to_fastplms_v1"
conversion_provenance = "Input: the pinned Biohub ESM3 checkpoint. Transformation: apply the deterministic esm3_to_fastplms_v1 parameter map for the supported sequence and multimodal modules and expand BF16 checkpoint tensors to FP32 storage. Output: the pinned Synthyra ESM3 checkpoint. Validation: release parity compares exact state identity after the declared map and live feature behavior. Limitation: unsupported upstream modalities may not be inferred from this record."
representative = "esm3_small"
documentation = "docs/models.md#esm3"
test_tiers = ["check", "compliance", "feature", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/esm3", "models/ttt.py"]
auto_map = { AutoConfig = "fastplms.models.esm3.modeling_esm3.FastESM3Config", AutoModel = "fastplms.models.esm3.modeling_esm3.FastESM3Model" }
[families.e1]
architecture = "E1"
upstreams = ["e1"]
tokenizer_mode = "sequence"
public_input = "Raw amino-acid sequences prepared by the native E1 adapter"
extra = "core"
reference_container = "reference-e1"
reference_adapter = "tests.parity.support.reference_adapters.e1"
attention = ["sdpa", "flex_attention"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "static_parameters"
precisions = ["default"]
vram_tier = "sequence"
checkpoint_license = "Profluent-E1-Agreement"
hub_license = "other"
hub_license_name = "Profluent-E1 Clickthrough License Agreement"
hub_license_link = "https://github.com/Profluent-AI/E1/blob/main/LICENSE"
weights_publication_allowed = true
state_transform = "e1_to_fastplms_v1"
conversion_provenance = "Input: the pinned Profluent-E1 checkpoint and tokenizer-free sequence contract. Transformation: apply e1_to_fastplms_v1 to the FastPLMs encoder and official task heads, storing floating tensors in BF16. Output: the pinned Synthyra Profluent-E1 checkpoint. Validation: release parity covers state identity after the declared cast, sequence and RAG preparation, aliases, and inference. Limitation: the FastPLMs scoring extension is not represented as an official E1 head."
representative = "e1_150m"
documentation = "docs/models.md#e1"
test_tiers = ["check", "compliance", "feature", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/e1", "models/ttt.py"]
auto_map = { AutoConfig = "fastplms.models.e1.modeling_e1.E1Config", AutoModel = "fastplms.models.e1.modeling_e1.E1Model", AutoModelForMaskedLM = "fastplms.models.e1.modeling_e1.E1ForMaskedLM", AutoModelForSequenceClassification = "fastplms.models.e1.modeling_e1.E1ForSequenceClassification", AutoModelForTokenClassification = "fastplms.models.e1.modeling_e1.E1ForTokenClassification" }
[families.dplm]
architecture = "DPLM"
upstreams = ["dplm"]
tokenizer_mode = "tokenizer"
public_input = "Amino-acid sequences tokenized to masked or partially masked residue IDs"
extra = "core"
reference_container = "reference-dplm"
reference_adapter = "tests.parity.support.reference_adapters.dplm"
attention = ["eager", "sdpa", "flex_attention", "flash_attention_3"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "fp32_parameters_autocast"
precisions = ["default"]
vram_tier = "sequence"
checkpoint_license = "Apache-2.0"
hub_license = "apache-2.0"
weights_publication_allowed = true
state_transform = "dplm_to_fastplms_v1"
conversion_provenance = "Input: the pinned official DPLM1 checkpoint. Transformation: apply dplm_to_fastplms_v1, omitting the unused absolute-position table for rotary checkpoints and materializing the tied input/output embedding values as independent tensors. Output: the pinned Synthyra DPLM checkpoint. Validation: release parity compares exact state identity after the declared transform, tokenizer behavior, generation, and inference. License basis: the pinned ByteDance DPLM Apache-2.0 LICENSE and README explicitly scope the repository release to the pretrained DPLM1 and DPLM2 weights; immutable evidence is recorded in LICENSES/dplm/PROVENANCE.md. Limitation: redistribution remains subject to Apache-2.0 and the pinned source record; no broader rights are inferred."
representative = "dplm_150m"
documentation = "docs/models.md#dplm"
test_tiers = ["check", "compliance", "feature", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/_diffusion_generation.py", "models/_esm_rotary.py", "models/dplm", "models/ttt.py"]
auto_map = { AutoConfig = "fastplms.models.dplm.modeling_dplm.DPLMConfig", AutoModel = "fastplms.models.dplm.modeling_dplm.DPLMModel", AutoModelForMaskedLM = "fastplms.models.dplm.modeling_dplm.DPLMForMaskedLM", AutoModelForSequenceClassification = "fastplms.models.dplm.modeling_dplm.DPLMForSequenceClassification", AutoModelForTokenClassification = "fastplms.models.dplm.modeling_dplm.DPLMForTokenClassification" }
[families.dplm2]
architecture = "DPLM2"
upstreams = ["dplm"]
tokenizer_mode = "tokenizer"
public_input = "Tokenized amino-acid and structure tracks with explicit modality boundaries"
extra = "core"
reference_container = "reference-dplm"
reference_adapter = "tests.parity.support.reference_adapters.dplm2"
attention = ["sdpa"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "fp32_parameters_autocast"
precisions = ["default"]
vram_tier = "sequence"
checkpoint_license = "Apache-2.0"
hub_license = "apache-2.0"
weights_publication_allowed = true
state_transform = "dplm2_to_fastplms_v1"
conversion_provenance = "Input: the pinned official DPLM2 checkpoint. Transformation: apply dplm2_to_fastplms_v1, retaining the independent language-model head and trained encoder contact head while omitting the unused absolute-position table for rotary checkpoints. Output: the pinned Synthyra DPLM2 checkpoint. Validation: release parity compares exact keys and values after the declared omission, non-aliasing, tokenizer behavior, generation, and inference. License basis: the pinned ByteDance DPLM Apache-2.0 LICENSE and README explicitly scope the repository release to the pretrained DPLM1 and DPLM2 weights; immutable evidence is recorded in LICENSES/dplm/PROVENANCE.md. Limitation: no head exception is permitted by this source record, and redistribution remains subject to Apache-2.0."
representative = "dplm2_150m"
documentation = "docs/models.md#dplm2"
test_tiers = ["check", "compliance", "feature", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/_diffusion_generation.py", "models/_esm_rotary.py", "models/dplm2", "models/ttt.py"]
auto_map = { AutoConfig = "fastplms.models.dplm2.modeling_dplm2.DPLM2Config", AutoModel = "fastplms.models.dplm2.modeling_dplm2.DPLM2Model", AutoModelForMaskedLM = "fastplms.models.dplm2.modeling_dplm2.DPLM2ForMaskedLM", AutoModelForSequenceClassification = "fastplms.models.dplm2.modeling_dplm2.DPLM2ForSequenceClassification", AutoModelForTokenClassification = "fastplms.models.dplm2.modeling_dplm2.DPLM2ForTokenClassification" }
tokenizer_class = "fastplms.models.dplm2.tokenization_dplm2.DPLM2Tokenizer"
[families.ankh]
architecture = "ANKH"
upstreams = ["ankh"]
tokenizer_mode = "tokenizer"
public_input = "Amino-acid sequences tokenized for encoder or sequence-to-sequence use"
extra = "core"
reference_container = "reference-ankh"
reference_adapter = "tests.parity.support.reference_adapters.ankh"
attention = ["eager", "sdpa"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "static_parameters"
precisions = ["default"]
vram_tier = "large-sequence"
checkpoint_license = "CC-BY-NC-SA-4.0"
hub_license = "cc-by-nc-sa-4.0"
weights_publication_allowed = true
state_transform = "ankh_t5_to_fastplms_v1"
conversion_provenance = "Input: the pinned official ANKH T5 checkpoint. Transformation: apply ankh_t5_to_fastplms_v1 to the official encoder and sequence-to-sequence heads. Output: the pinned Synthyra ANKH checkpoint. Validation: release parity compares exact mapped state, tokenizer behavior, official heads, and inference. Limitation: the separately named FastPLMs masked-language-model extension is not an official ANKH head."
representative = "ankh_base"
documentation = "docs/models.md#ankh"
test_tiers = ["check", "compliance", "feature", "artifact", "benchmark"]
requires_complete_weight_publication = false
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/ankh", "models/ttt.py"]
auto_map = { AutoConfig = "fastplms.models.ankh.modeling_ankh.FastAnkhConfig", AutoModel = "fastplms.models.ankh.modeling_ankh.FastAnkhModel", AutoModelForMaskedLM = "fastplms.models.ankh.modeling_ankh.FastAnkhForMaskedLMExtension", AutoModelForSeq2SeqLM = "fastplms.models.ankh.modeling_ankh.FastAnkhForConditionalGeneration", AutoModelForSequenceClassification = "fastplms.models.ankh.modeling_ankh.FastAnkhForSequenceClassification", AutoModelForTokenClassification = "fastplms.models.ankh.modeling_ankh.FastAnkhForTokenClassification" }
[families.boltz2]
architecture = "Boltz2"
upstreams = ["boltz"]
tokenizer_mode = "structure"
public_input = "Raw amino-acid sequences through the convenience API, or prepared model features"
extra = "structure"
reference_container = "reference-boltz2"
reference_adapter = "tests.parity.support.reference_adapters.boltz"
attention = ["eager"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "fp32_parameters_autocast"
precisions = ["default"]
vram_tier = "structure"
checkpoint_license = "MIT"
hub_license = "mit"
weights_publication_allowed = true
state_transform = "boltz2_inference_core_v1"
conversion_provenance = "Input: the pinned official Boltz2 checkpoint. Transformation: select and map the supported Boltz2 inference-core parameters with boltz2_inference_core_v1. Output: the pinned Synthyra Boltz2 checkpoint. Validation: release parity covers state identity for the declared subset, feature preparation, seeded inference, and structure outputs. Limitation: this record does not claim support for undeclared upstream training components."
representative = "boltz2"
documentation = "docs/models.md#boltz2"
test_tiers = ["structure", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "models/boltz"]
auto_map = { AutoConfig = "fastplms.models.boltz.modeling_boltz2.Boltz2Config", AutoModel = "fastplms.models.boltz.modeling_boltz2.Boltz2Model" }
[families.esmfold]
architecture = "ESMFold"
upstreams = ["fair-esm", "openfold"]
tokenizer_mode = "structure"
public_input = "Raw amino-acid sequences through folding helpers, or prepared residue tensors"
extra = "structure"
reference_container = "reference-esmfold"
reference_adapter = "tests.parity.support.reference_adapters.esmfold"
attention = ["eager", "sdpa", "flex_attention"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "fp32_parameters_autocast"
precisions = ["default"]
vram_tier = "structure"
checkpoint_license = "MIT"
hub_license = "mit"
weights_publication_allowed = true
state_transform = "esmfold_meta_to_fastplms_v1"
conversion_provenance = "Input: the pinned native Meta ESMFold checkpoint plus its pinned ESM2 backbone. Transformation: apply esmfold_meta_to_fastplms_v1 to map native ESM2 names into the structure-only FastPLMs backbone, retain folding tensors, omit five deterministically reconstructed geometry buffers, omit the folding-unused ESM2 masked-LM and contact-regression heads, and remove the obsolete random FastPLMs TTT head from earlier mirrors. Output: canonical FP32 FastPLMs ESMFold state with an explicit CUDA BF16-autocast execution path. Validation: release parity compares exact mapped keys, shapes, dtypes, values, aliases, semantic configuration, FP32 and BF16-compute seeded inference, and structure metrics with pLDDT normalized to (0, 1). Limitation: ESMFold TTT is rejected because the official checkpoint contains no trained masked-language-model head."
representative = "esmfold"
documentation = "docs/models.md#esmfold"
test_tiers = ["check", "compliance", "structure", "feature", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/_esm_rotary.py", "models/esmfold"]
auto_map = { AutoConfig = "fastplms.models.esmfold.modeling_fast_esmfold.FastEsmFoldConfig", AutoModel = "fastplms.models.esmfold.modeling_fast_esmfold.FastEsmForProteinFolding" }
[families.esmfold2]
architecture = "ESMFold2"
upstreams = ["biohub-esm", "biohub-transformers", "protein-ttt"]
backbone_model = "esmc_6b"
tokenizer_mode = "structure"
public_input = "Raw amino-acid sequences or typed molecular-complex specifications; low-level forward accepts prepared feature tensors"
extra = "structure"
reference_container = "reference-esmfold2"
reference_adapter = "tests.parity.support.reference_adapters.esmfold2"
attention = ["eager", "sdpa", "flex_attention"]
dtypes = ["float32", "bfloat16"]
bf16_execution = "fp32_parameters_autocast"
precisions = ["auto", "fp32", "bf16", "fp8"]
experimental_precisions = ["fp8"]
vram_tier = "structure-6b"
checkpoint_license = "MIT"
hub_license = "mit"
weights_publication_allowed = true
state_transform = "identity"
conversion_provenance = "Input: each pinned Biohub ESMFold2 checkpoint and its separately pinned ESMC checkpoint. Transformation: apply identity to preserve the folding checkpoint exactly, load its parameters in FP32 for CUDA BF16-autocast execution, retain canonical BF16 ESMC weights, and optionally rebuild exactly 80 ESMC attention output projections as transient Transformer Engine linears. Output: the corresponding pinned Synthyra ESMFold2 checkpoint plus its declared ESMC precision policy. Validation: release parity covers exact canonical state, learned projection, prepared features, and seeded BF16 folding; experimental FP8 validation covers strict unavailable-device behavior, all four variants, and three BF16-to-FP8 reload cycles on the standard variant. Limitation: only the four manifest-listed ESMFold2 variants are supported; FP8 is experimental, applies only to inference-time ESMC execution, and requires direct CUDA loading with Transformer Engine availability."
representative = "esmfold2"
documentation = "docs/esmfold2.md"
test_tiers = ["check", "compliance", "structure", "feature", "artifact", "benchmark"]
runtime_paths = ["__init__.py", "registry.py", "runtime.py", "models.toml", "models/__init__.py", "attention", "embeddings", "models/esmfold2", "models/esm_plusplus", "models/ttt.py"]
auto_map = { AutoConfig = "fastplms.models.esmfold2.configuration_esmfold2.ESMFold2Config", AutoModel = "fastplms.models.esmfold2.modeling_esmfold2.ESMFold2Model" }
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role = "weights"
path = "models/esm2_t36_3B_UR50D.pt"
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sha256 = "7de8b4082ba15891959ab368b77ce3886697af1efb16d3c9e9e7b0c5d3f07500"
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role = "contact_regression"
path = "regression/esm2_t36_3B_UR50D-contact-regression.pt"
url = "https://dl.fbaipublicfiles.com/fair-esm/regression/esm2_t36_3B_UR50D-contact-regression.pt"
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id = "esmc_small"
family = "esm_plusplus"
size_category = "medium"
generation_contract = "not_applicable"
official_golden = { metadata = "tests/goldens/esmc_small.json=sha256:bb02652cf3cc484756b98ffa4ba55ed4c55870d2cea3342adb1d920ba9dfe10a", tensors = "tests/goldens/esmc_small.safetensors=sha256:03378d0f0fdd8161178ebb2c1f0da1b9776a726c8e8d3a10c009808a24de5654" }
notes = "Release contract: SDPA must match the pinned Biohub implementation bit-for-bit across every hidden state, last hidden state, logits, special token, and padding position. Eager and FlashAttention 2 are release-gated in BF16 against the pinned boundary-length and biological panels with a relative-L2 engineering target of 0.029, hard limit of 0.03, relative-Q99.9 target of 0.049, first-percentile residue-cosine target of 0.997, and Jensen-Shannon target of 0.0004. The global pooled-cosine and top-1 thresholds remain unchanged. Flex Attention and FlashAttention 3 remain selectable as opt-in alternatives, but they are not strict-parity choices: on the locked H100 BF16 generated-boundary panel, ESMC-6B Flex Attention exceeds the 0.03 relative-L2 hard limit and FlashAttention 3 falls below the 0.995 residue-cosine hard limit. The deviation is consistent with backend-specific BF16 kernel arithmetic; it is not a weight-conversion difference or silent fallback. Use SDPA for exact Biohub parity or FlashAttention 2 for release-gated acceleration."
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fast_revision = "46c5f7d562e47d4c14165b424c71ab7db008e6fb"
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id = "esmc_large"
family = "esm_plusplus"
size_category = "large"
generation_contract = "not_applicable"
official_golden = { metadata = "tests/goldens/esmc_large.json=sha256:7a4d614f67b6fde417f3fd89f61e7ec442ae284769734b2b73e14945a816a8fd", tensors = "tests/goldens/esmc_large.safetensors=sha256:e13302df4cf7e8381552f1043a8fd0f31f3e0d50b2ab6009fb86b7940ae8ff79" }
notes = "Release contract: SDPA must match the pinned Biohub implementation bit-for-bit across every hidden state, last hidden state, logits, special token, and padding position. Eager and FlashAttention 2 are release-gated in BF16 against the pinned boundary-length and biological panels with a relative-L2 engineering target of 0.029, hard limit of 0.03, relative-Q99.9 target of 0.049, first-percentile residue-cosine target of 0.997, and Jensen-Shannon target of 0.0004. The global pooled-cosine and top-1 thresholds remain unchanged. Flex Attention and FlashAttention 3 remain selectable as opt-in alternatives, but they are not strict-parity choices: on the locked H100 BF16 generated-boundary panel, ESMC-6B Flex Attention exceeds the 0.03 relative-L2 hard limit and FlashAttention 3 falls below the 0.995 residue-cosine hard limit. The deviation is consistent with backend-specific BF16 kernel arithmetic; it is not a weight-conversion difference or silent fallback. Use SDPA for exact Biohub parity or FlashAttention 2 for release-gated acceleration."
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fast_revision = "f813401638b3fddab09748aec1ad2bf537aa4208"
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id = "esmc_6b"
family = "esm_plusplus"
size_category = "xlarge"
generation_contract = "not_applicable"
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notes = "Release contract: SDPA must match the pinned Biohub implementation bit-for-bit across every hidden state, last hidden state, logits, special token, and padding position. Eager and FlashAttention 2 are release-gated in BF16 against the pinned boundary-length and biological panels with a relative-L2 engineering target of 0.029, hard limit of 0.03, relative-Q99.9 target of 0.049, first-percentile residue-cosine target of 0.997, and Jensen-Shannon target of 0.0004. The global pooled-cosine and top-1 thresholds remain unchanged. Flex Attention and FlashAttention 3 remain selectable as opt-in alternatives, but they are not strict-parity choices: on the locked H100 BF16 generated-boundary panel, ESMC-6B Flex Attention exceeds the 0.03 relative-L2 hard limit and FlashAttention 3 falls below the 0.995 residue-cosine hard limit. The deviation is consistent with backend-specific BF16 kernel arithmetic; it is not a weight-conversion difference or silent fallback. Use SDPA for exact Biohub parity or FlashAttention 2 for release-gated acceleration."
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fast_revision = "0d579cce3b0f09efa6b3baddf6cc3fd8c9b616c8"
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official_repo = "airkingbd/dplm_3b"
official_revision = "53849d4a7fe944ae0b9cf2bbc0d2cc0054795b51"
official_files = [
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[[models]]
id = "dplm2_150m"
family = "dplm2"
size_category = "small"
generation_contract = "required"
official_golden = { metadata = "tests/goldens/dplm2_150m.json=sha256:d269de779ea1503de72c77e7b2e6224afc9797bd945b40c571ff6faec782e4aa", tensors = "tests/goldens/dplm2_150m.safetensors=sha256:17fc26600938ba5364b8ecb96750786d33e9f92bcd4ea4df3e12a389340748eb" }
artifact_source = "official"
canonical_state_sha256 = "82e1751f59052b8de72b082517557db47947e8d9b4ac2f11278369e6c0cbf001"
fast_repo = "Synthyra/DPLM2-150M"
fast_revision = "182745b8dc5661f898481a4fa60a7af9d53385c4"
fast_files = [
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"tokenizer_config.json=git-sha1:f2090783e3368b7323aa877e2b740e09f0862259",
"vocab.txt=git-sha1:9706a4277a5c39dc9b4ec7b283e8eb130ceaa7f2",
]
official_repo = "airkingbd/dplm2_150m"
official_revision = "3451d984d06497f835ed49634bd68c9dfb54d730"
official_files = [
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[[models]]
id = "dplm2_650m"
family = "dplm2"
size_category = "large"
generation_contract = "required"
official_golden = { metadata = "tests/goldens/dplm2_650m.json=sha256:d9a7548f9af657a72d441ca70f27379863724fcce8ddd3da4f672104b7bfb772", tensors = "tests/goldens/dplm2_650m.safetensors=sha256:c4e0e467c252c3ac813363d2d4b17a5e3bd99e75fad315e76d97689b4655ddac" }
artifact_source = "official"
canonical_state_sha256 = "cba76b6602d2258de9fffff953b608d93cb8ef4a9e89b0bbd27e160c81e78bb4"
fast_repo = "Synthyra/DPLM2-650M"
fast_revision = "b9d8527a9473a54954fa2764f590b9ea1b435bb2"
fast_files = [
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"vocab.txt=git-sha1:9706a4277a5c39dc9b4ec7b283e8eb130ceaa7f2",
]
official_repo = "airkingbd/dplm2_650m"
official_revision = "0bc69b644976c6680ab7e26669854d1979e8876e"
official_files = [
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[[models]]
id = "dplm2_3b"
family = "dplm2"
size_category = "xlarge"
# The pinned public sampler fails before generation because cls_token_id is None.
# State, tokenizer, and inference parity remain required for this checkpoint.
generation_contract = "official_unavailable"
official_golden = { metadata = "tests/goldens/dplm2_3b.json=sha256:d6e0e02af53b13cb129192f06e264758aa21c9ebf4ee82411cf67037082d2329", tensors = "tests/goldens/dplm2_3b.safetensors=sha256:838b11824d08f83bcb0c0b3268e579f3a87dbfb965370cfe5c3f8793b96b1964" }
notes = "The pinned official DPLM2-3B sampler fails before generation, so live generation equivalence cannot be established for this checkpoint. State, tokenizer, and inference parity remain required."
artifact_source = "official"
canonical_state_sha256 = "8c46ec09115dbe6cbfb91d94ab5e906369d57e27fe620a7741c6f8cb1b6ca890"
fast_repo = "Synthyra/DPLM2-3B"
fast_revision = "2a63babe8848abf5233d31bd55891dff8285fc50"
fast_files = [
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official_repo = "airkingbd/dplm2_3b"
official_revision = "9e77567926f98d1b997ea9131a8eeb035b9bf827"
official_files = [
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[[models]]
id = "ankh_base"
family = "ankh"
size_category = "medium"
generation_contract = "required"
official_golden = { metadata = "tests/goldens/ankh_base.json=sha256:ebce8d7de821827ee995789c9b38d79252d3b2f76888130b0a8a7eedafaefe2b", tensors = "tests/goldens/ankh_base.safetensors=sha256:f0e78aa15d11749e0c64ff57f9e88c51cec6538a0adf8951f839df70cc708b65" }
notes = "ANKH parity covers the official encoder and sequence-to-sequence heads. AutoModelForMaskedLM exposes the separately named FastPLMs synthesized masked-LM extension and is not an official ANKH head."
artifact_source = "official"
canonical_state_sha256 = "cdd8d30d88e5bf41f44e1eef4470d8e46607aba5f7c7c805b06c035b89c8c16f"
fast_repo = "Synthyra/ANKH_base"
fast_revision = "a3afa1db21c876dff57b3540fa7241e138fb1ed6"
fast_files = [
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official_repo = "ElnaggarLab/ankh-base"
official_revision = "d99cb6b966530dfc2ae96bc69d9255c2a07308b0"
official_files = [
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]
[[models]]
id = "ankh_large"
family = "ankh"
size_category = "large"
generation_contract = "required"
official_golden = { metadata = "tests/goldens/ankh_large.json=sha256:59492518b021de5cfaea87d672c9448c8558e99a3443ba2cc7ab544963196ecb", tensors = "tests/goldens/ankh_large.safetensors=sha256:3fb8d3ac27716d15a9ea92aeef6acf2b977bcc887d9b535000539e523673459b" }
notes = "ANKH parity covers the official encoder and sequence-to-sequence heads. AutoModelForMaskedLM exposes the separately named FastPLMs synthesized masked-LM extension and is not an official ANKH head."
artifact_source = "official"
canonical_state_sha256 = "e498a2e9aea76ef784cbe3e596c6b3f5e9a40e209ad837f7e3207099e4d74483"
fast_repo = "Synthyra/ANKH_large"
fast_revision = "92d2403bbe3c32acaa944fbb8dc2beb5f571f008"
fast_files = [
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official_repo = "ElnaggarLab/ankh-large"
official_revision = "74b371dbfa3ee0a05d32ae74df0c2e0b82d6b9a6"
official_files = [
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]
[[models]]
id = "ankh2_large"
family = "ankh"
size_category = "large"
generation_contract = "required"
official_golden = { metadata = "tests/goldens/ankh2_large.json=sha256:e8df38994ca1a1e0c598ace34a0b257b264937e4fdbb01bc41544985116b02a4", tensors = "tests/goldens/ankh2_large.safetensors=sha256:25fe1569f55c635fab8fa49c1d62a889a35a2a738bad921f5764a85b58fd4b5d" }
notes = "ANKH parity covers the official encoder and sequence-to-sequence heads. AutoModelForMaskedLM exposes the separately named FastPLMs synthesized masked-LM extension and is not an official ANKH head."
artifact_source = "official"
canonical_state_sha256 = "597c4fe2fa8711f11a25317905f1d62fa92905e55fdd5c0a79614cd9c9d2bca3"
fast_repo = "Synthyra/ANKH2_large"
fast_revision = "729167c1980316ae61691338838447491926033f"
fast_files = [
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official_repo = "ElnaggarLab/ankh2-ext2"
official_revision = "aa9b9fa72288c47d9f618ce80c011e24b54e17a8"
official_files = [
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]
[[models]]
id = "ankh3_large"
family = "ankh"
size_category = "large"
generation_contract = "required"
official_golden = { metadata = "tests/goldens/ankh3_large.json=sha256:2e5bb05b3baa5baa78f61fef7d2a2c669b0da5dbfaf6b50b12abd3e17253a961", tensors = "tests/goldens/ankh3_large.safetensors=sha256:e5c494ac418e0a2fe7bdad1376676d48960d58ec9e044d19bfffccb8c3288513" }
notes = "ANKH parity covers the official encoder and sequence-to-sequence heads. AutoModelForMaskedLM exposes the separately named FastPLMs synthesized masked-LM extension and is not an official ANKH head."
artifact_source = "official"
canonical_state_sha256 = "60acb7ef86e85dc0c51fc1edf4c8e69a0480049723b6b2c95e6e9faa720c112a"
fast_repo = "Synthyra/ANKH3_large"
fast_revision = "c6d16ca2a1b3b27a27bcf3875e816a059029d264"
fast_files = [
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official_repo = "ElnaggarLab/ankh3-large"
official_revision = "2be091622e8a393f0ef21735070084123c874b6e"
official_files = [
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[[models]]
id = "ankh3_xl"
family = "ankh"
size_category = "xlarge"
generation_contract = "required"
official_golden = { metadata = "tests/goldens/ankh3_xl.json=sha256:66bb12e033e4163be225d636108a479393228a4f5061015c8af114e766c3c486", tensors = "tests/goldens/ankh3_xl.safetensors=sha256:72d34567d0228cb6f1ee701c578ed4039fead4346e3f161a52e0e74df28dc8ae" }
notes = "ANKH parity covers the official encoder and sequence-to-sequence heads. AutoModelForMaskedLM exposes the separately named FastPLMs synthesized masked-LM extension and is not an official ANKH head. The official PyTorch shard index is deliberately excluded: the builder verifies every declared source shard directly and writes a new canonical safetensors index."
artifact_source = "official"
canonical_state_sha256 = "dd2188e0d2ca65232135714eef6de394239734d843ddae4928c7398685d858e7"
fast_repo = "Synthyra/ANKH3_xl"
fast_revision = "d2856892e7535af2f55c2c4de043b1b272a29ed8"
fast_files = [
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