# Arc State Norman fine-tuning split.
# Explicit train/test perturbation lists for the GEARS simulation
# split (seed=1): 139 train + 107 test, zero overlap.

[datasets]
norman = "data/processed/norman_state.h5ad"   # adjust to your local path

[training]
norman = "train"

[zeroshot]

[fewshot."norman.A549"]
train = [
  "TSC22D1+ctrl",
  "ctrl",
  "CEBPE+RUNX1T1",
  "MAML2+ctrl",
  "ctrl+CEBPE",
  "SGK1+TBX3",
  "ctrl+FOXA1",
  "FOXA3+FOXA1",
  "ETS2+IGDCC3",
  "GLB1L2+ctrl",
  "MAP2K6+IKZF3",
  "BAK1+ctrl",
  "FEV+ctrl",
  "MAP2K3+SLC38A2",
  "ctrl+ETS2",
  "ctrl+FEV",
  "ctrl+SET",
  "TBX3+ctrl",
  "LHX1+ctrl",
  "RREB1+ctrl",
  "ZNF318+ctrl",
  "ctrl+ZBTB25",
  "MAP4K5+ctrl",
  "UBASH3B+ctrl",
  "SLC6A9+ctrl",
  "MIDN+ctrl",
  "DLX2+ctrl",
  "CBFA2T3+ctrl",
  "HES7+ctrl",
  "SET+CEBPE",
  "IGDCC3+ZBTB25",
  "AHR+ctrl",
  "FOXO4+ctrl",
  "ctrl+CBFA2T3",
  "ctrl+RUNX1T1",
  "POU3F2+ctrl",
  "ctrl+CNN1",
  "IGDCC3+MAPK1",
  "MAP2K3+ctrl",
  "MAP4K3+ctrl",
  "ZBTB25+ctrl",
  "ZC3HAV1+CEBPE",
  "UBASH3B+UBASH3A",
  "MAP2K3+MAP2K6",
  "PTPN1+ctrl",
  "RUNX1T1+ctrl",
  "PTPN12+ctrl",
  "TP73+ctrl",
  "ctrl+MAP7D1",
  "FOSB+ctrl",
  "MAPK1+ctrl",
  "IRF1+ctrl",
  "TMSB4X+BAK1",
  "BPGM+SAMD1",
  "IKZF3+ctrl",
  "HOXB9+ctrl",
  "ctrl+HOXC13",
  "MAPK1+IKZF3",
  "ctrl+UBASH3B",
  "ctrl+HOXB9",
  "ETS2+ctrl",
  "CLDN6+ctrl",
  "FOXA3+ctrl",
  "CEBPE+ctrl",
  "KIF18B+KIF2C",
  "ctrl+SAMD1",
  "COL1A1+ctrl",
  "PTPN12+UBASH3A",
  "FOXF1+ctrl",
  "FEV+MAP7D1",
  "PLK4+ctrl",
  "BPGM+ctrl",
  "LYL1+ctrl",
  "ctrl+MAP2K6",
  "SGK1+ctrl",
  "MAPK1+TGFBR2",
  "ctrl+DLX2",
  "MAP2K6+ctrl",
  "ctrl+TBX3",
  "CNN1+ctrl",
  "ctrl+CEBPA",
  "HNF4A+ctrl",
  "MAP7D1+ctrl",
  "PTPN12+SNAI1",
  "KMT2A+ctrl",
  "CNN1+UBASH3A",
  "IGDCC3+ctrl",
  "ISL2+ctrl",
  "TGFBR2+IGDCC3",
  "TMSB4X+ctrl",
  "KIF2C+ctrl",
  "ctrl+CLDN6",
  "ctrl+KIF2C",
  "IRF1+SET",
  "CSRNP1+ctrl",
  "CEBPE+CEBPA",
  "ctrl+UBASH3A",
  "NCL+ctrl",
  "ctrl+BAK1",
  "ctrl+IKZF3",
  "FOXF1+HOXB9",
  "UBASH3B+CNN1",
  "ZC3HAV1+ctrl",
  "SET+ctrl",
  "FOSB+UBASH3B",
  "SNAI1+UBASH3B",
  "ctrl+STIL",
  "HOXC13+ctrl",
  "ATL1+ctrl",
  "CEBPE+PTPN12",
  "CEBPA+ctrl",
  "NIT1+ctrl",
  "SAMD1+UBASH3B",
  "TGFBR2+ctrl",
  "SAMD1+TGFBR2",
  "FOXA1+ctrl",
  "SAMD1+ctrl",
  "ctrl+MAPK1",
  "UBASH3A+ctrl",
  "AHR+FEV",
  "ETS2+IKZF3",
  "ctrl+ISL2",
  "ctrl+SLC38A2",
  "PTPN12+ZBTB25",
  "ctrl+SNAI1",
  "HOXA13+ctrl",
  "ctrl+FOXF1",
  "ctrl+PTPN12",
  "SAMD1+PTPN12",
  "HK2+ctrl",
  "ctrl+IGDCC3",
  "ctrl+TGFBR2",
  "FOXA3+FOXF1",
  "ZC3HAV1+CEBPA",
  "KIF18B+ctrl",
  "SNAI1+ctrl",
  "FOXA1+FOXF1",
  "PLK4+STIL",
  "STIL+ctrl",
]
test = [
  "CBL+PTPN9",
  "DUSP9+ctrl",
  "MAP2K6+SPI1",
  "UBASH3B+PTPN12",
  "BCORL1+ctrl",
  "MEIS1+ctrl",
  "CBL+ctrl",
  "KLF1+FOXA1",
  "TBX3+TBX2",
  "SLC4A1+ctrl",
  "DUSP9+MAPK1",
  "COL2A1+ctrl",
  "CEBPE+KLF1",
  "UBASH3B+OSR2",
  "UBASH3B+ZBTB25",
  "DUSP9+ETS2",
  "ZNF318+FOXL2",
  "UBASH3B+PTPN9",
  "S1PR2+ctrl",
  "CELF2+ctrl",
  "JUN+CEBPA",
  "CDKN1A+ctrl",
  "ctrl+MEIS1",
  "MAPK1+PRTG",
  "MAP2K3+IKZF3",
  "KLF1+COL2A1",
  "PTPN12+OSR2",
  "ETS2+CEBPE",
  "POU3F2+FOXL2",
  "DUSP9+PRTG",
  "CKS1B+ctrl",
  "BCL2L11+TGFBR2",
  "AHR+KLF1",
  "CEBPB+CEBPA",
  "PRTG+ctrl",
  "ETS2+CNN1",
  "C3orf72+ctrl",
  "CNN1+MAPK1",
  "FOXL2+MEIS1",
  "FOXL2+ctrl",
  "FOSB+CEBPE",
  "PTPN12+PTPN9",
  "FOSB+CEBPB",
  "ctrl+CDKN1A",
  "BCL2L11+BAK1",
  "FOXA3+HOXB9",
  "ARID1A+ctrl",
  "ctrl+COL2A1",
  "CEBPE+CNN1",
  "ZC3HAV1+HOXC13",
  "CBL+CNN1",
  "ZBTB10+PTPN12",
  "CBL+UBASH3B",
  "CEBPB+PTPN12",
  "BCL2L11+ctrl",
  "OSR2+ctrl",
  "ctrl+SPI1",
  "CEBPB+MAPK1",
  "ETS2+MAPK1",
  "DUSP9+IGDCC3",
  "CEBPB+ctrl",
  "CBL+PTPN12",
  "CEBPB+OSR2",
  "ctrl+PRTG",
  "SGK1+S1PR2",
  "DUSP9+KLF1",
  "CDKN1B+ctrl",
  "FEV+ISL2",
  "JUN+ctrl",
  "POU3F2+CBFA2T3",
  "FOXA1+HOXB9",
  "ZBTB10+ctrl",
  "CEBPE+SPI1",
  "PTPN13+ctrl",
  "CBL+TGFBR2",
  "FOXA1+FOXL2",
  "FOXF1+FOXL2",
  "ETS2+PRTG",
  "PTPN9+ctrl",
  "LYL1+CEBPB",
  "DUSP9+SNAI1",
  "ctrl+CEBPB",
  "TGFBR2+PRTG",
  "PRDM1+ctrl",
  "FOSB+OSR2",
  "FOXL2+HOXB9",
  "ctrl+PTPN9",
  "ctrl+OSR2",
  "ZBTB10+ELMSAN1",
  "JUN+CEBPB",
  "ZBTB10+SNAI1",
  "ctrl+FOXL2",
  "CEBPE+CEBPB",
  "PRDM1+CBFA2T3",
  "FOXA3+FOXL2",
  "CDKN1C+CDKN1B",
  "CDKN1C+CDKN1A",
  "SPI1+ctrl",
  "EGR1+ctrl",
  "ZBTB10+DLX2",
  "CBL+UBASH3A",
  "SNAI1+DLX2",
  "IGDCC3+PRTG",
  "CDKN1C+ctrl",
  "ctrl+CDKN1B",
  "CDKN1B+CDKN1A",
  "C3orf72+FOXL2",
]