[{"prompt": "What causes Yellow Fever Disease?", "completion": "Large scale outbreaks occur every 3 to 10 years in villages or cities in the absence of large scale immunisation. Sporadic cases can occur regularly in endemic areas. Resurgence of disease in Africa since mid-1980s. True incidence far exceeds reported cases. Incubation period 3 to 6 days after the bite from an infected mosquito. About 15% of infections progress to fever and jaundice. Acute viral hemorrhagic disease caused by a flavivirus transmitted human-to-human via the domestic species of Aedes mosquitoes (Urban epidemics) or to humans from primate reservoir via a forest mosquito species (Sylvatic cycle)."}, {"prompt": "Explain the transmission of Yellow Fever Disease.", "completion": "Large scale outbreaks occur every 3 to 10 years in villages or cities in the absence of large scale immunisation. Sporadic cases can occur regularly in endemic areas. Resurgence of disease in Africa since mid-1980s. True incidence far exceeds reported cases. Incubation period 3 to 6 days after the bite from an infected mosquito. About 15% of infections progress to fever and jaundice. Acute viral hemorrhagic disease caused by a flavivirus transmitted human-to-human via the domestic species of Aedes mosquitoes (Urban epidemics) or to humans from primate reservoir via a forest mosquito species (Sylvatic cycle)."}, {"prompt": "Describe the symptoms of Yellow Fever Disease.", "completion": "Large scale outbreaks occur every 3 to 10 years in villages or cities in the absence of large scale immunisation. Sporadic cases can occur regularly in endemic areas. Resurgence of disease in Africa since mid-1980s. True incidence far exceeds reported cases. Incubation period 3 to 6 days after the bite from an infected mosquito. About 15% of infections progress to fever and jaundice. Acute viral hemorrhagic disease caused by a flavivirus transmitted human-to-human via the domestic species of Aedes mosquitoes (Urban epidemics) or to humans from primate reservoir via a forest mosquito species (Sylvatic cycle)."}, {"prompt": "How often do large scale outbreaks of Yellow Fever Disease occur?", "completion": "Large scale outbreaks occur every 3 to 10 years in villages or cities in the absence of large scale immunisation. Sporadic cases can occur regularly in endemic areas. Resurgence of disease in Africa since mid-1980s. True incidence far exceeds reported cases. Incubation period 3 to 6 days after the bite from an infected mosquito. About 15% of infections progress to fever and jaundice. Acute viral hemorrhagic disease caused by a flavivirus transmitted human-to-human via the domestic species of Aedes mosquitoes (Urban epidemics) or to humans from primate reservoir via a forest mosquito species (Sylvatic cycle)."}, {"prompt": "What percentage of Yellow Fever Disease infections progress to fever and jaundice?", "completion": "Large scale outbreaks occur every 3 to 10 years in villages or cities in the absence of large scale immunisation. Sporadic cases can occur regularly in endemic areas. Resurgence of disease in Africa since mid-1980s. True incidence far exceeds reported cases. Incubation period 3 to 6 days after the bite from an infected mosquito. About 15% of infections progress to fever and jaundice. Acute viral hemorrhagic disease caused by a flavivirus transmitted human-to-human via the domestic species of Aedes mosquitoes (Urban epidemics) or to humans from primate reservoir via a forest mosquito species (Sylvatic cycle)."}, {"prompt": "Why is Yellow Fever Disease considered a priority?", "completion": "While only the minority of cases are severe, the case fatality rate may be 25% to 50% among patients with a syndrome of hemorrhage, jaundice, and renal disease."}, {"prompt": "What makes Yellow Fever Disease a critical public health concern?", "completion": "While only the minority of cases are severe, the case fatality rate may be 25% to 50% among patients with a syndrome of hemorrhage, jaundice, and renal disease."}, {"prompt": "What are the severe outcomes of Yellow Fever Disease?", "completion": "While only the minority of cases are severe, the case fatality rate may be 25% to 50% among patients with a syndrome of hemorrhage, jaundice, and renal disease."}, {"prompt": "Explain the impact of Yellow Fever Disease on affected communities.", "completion": "While only the minority of cases are severe, the case fatality rate may be 25% to 50% among patients with a syndrome of hemorrhage, jaundice, and renal disease."}, {"prompt": "What are the risk factors for Yellow Fever Disease?", "completion": "Sporadic cases often linked to occupation or village location near woods or where monkeys are numerous. Also, non-vaccinated persons."}, {"prompt": "Who is at higher risk of contracting Yellow Fever Disease?", "completion": "Sporadic cases often linked to occupation or village location near woods or where monkeys are numerous. Also, non-vaccinated persons."}, {"prompt": "What are the factors that increase the likelihood of Yellow Fever Disease transmission?", "completion": "Sporadic cases often linked to occupation or village location near woods or where monkeys are numerous. Also, non-vaccinated persons."}, {"prompt": "How can individuals protect themselves from Yellow Fever Disease?", "completion": "Sporadic cases often linked to occupation or village location near woods or where monkeys are numerous. Also, non-vaccinated persons."}, {"prompt": "What are the surveillance goals for Yellow Fever Disease?", "completion": "Seek confirmation of yellow fever and rule out other possible etiologies of fever with jaundice. Provide information to adopt appropriate control measures. Identify populations at risk of yellow fever. Monitor the epidemiology of the disease and the impact of control measures. Support operational research and innovation."}, {"prompt": "How does the surveillance system help in controlling Yellow Fever Disease outbreaks?", "completion": "Seek confirmation of yellow fever and rule out other possible etiologies of fever with jaundice. Provide information to adopt appropriate control measures. Identify populations at risk of yellow fever. Monitor the epidemiology of the disease and the impact of control measures. Support operational research and innovation."}, {"prompt": "What is the importance of monitoring yellow fever cases? related to Yellow Fever Disease", "completion": "Seek confirmation of yellow fever and rule out other possible etiologies of fever with jaundice. Provide information to adopt appropriate control measures. Identify populations at risk of yellow fever. Monitor the epidemiology of the disease and the impact of control measures. Support operational research and innovation."}, {"prompt": "How does surveillance contribute to the prevention of Yellow Fever Disease outbreaks?", "completion": "Seek confirmation of yellow fever and rule out other possible etiologies of fever with jaundice. Provide information to adopt appropriate control measures. Identify populations at risk of yellow fever. Monitor the epidemiology of the disease and the impact of control measures. Support operational research and innovation."}, {"prompt": "What is the standard case definition for a suspected new case of Yellow Fever Disease?", "completion": "Any person with acute onset of fever, with either a negative laboratory test (blood slide or RDT) for malaria or failure to respond to a full course of antimalarials AND any one of the following: 1. Jaundice or scleral icterus appearing within 14 days of onset of the first symptoms. 2. Bleeding from either the mouth, nose, gums, skin, eyes, or stomach (gastrointestinal tract)."}, {"prompt": "How can health professionals identify a potential Yellow Fever Disease case?", "completion": "Any person with acute onset of fever, with either a negative laboratory test (blood slide or RDT) for malaria or failure to respond to a full course of antimalarials AND any one of the following: 1. Jaundice or scleral icterus appearing within 14 days of onset of the first symptoms. 2. Bleeding from either the mouth, nose, gums, skin, eyes, or stomach (gastrointestinal tract)."}, {"prompt": "What are the symptoms that should raise suspicion of Yellow Fever Disease?", "completion": "Any person with acute onset of fever, with either a negative laboratory test (blood slide or RDT) for malaria or failure to respond to a full course of antimalarials AND any one of the following: 1. Jaundice or scleral icterus appearing within 14 days of onset of the first symptoms. 2. Bleeding from either the mouth, nose, gums, skin, eyes, or stomach (gastrointestinal tract)."}, {"prompt": "What tests should be conducted to suspect Yellow Fever Disease?", "completion": "Any person with acute onset of fever, with either a negative laboratory test (blood slide or RDT) for malaria or failure to respond to a full course of antimalarials AND any one of the following: 1. Jaundice or scleral icterus appearing within 14 days of onset of the first symptoms. 2. Bleeding from either the mouth, nose, gums, skin, eyes, or stomach (gastrointestinal tract)."}, {"prompt": "What is the standard case definition for a probable case of Yellow Fever Disease?", "completion": "Any person meeting the suspect case definition criteria with an epidemiological link."}, {"prompt": "How do health authorities identify a probable Yellow Fever Disease case?", "completion": "Any person meeting the suspect case definition criteria with an epidemiological link."}, {"prompt": "What are the factors that raise the probability of a Yellow Fever Disease case?", "completion": "Any person meeting the suspect case definition criteria with an epidemiological link."}, {"prompt": "What actions should be taken if a probable Yellow Fever Disease case is identified?", "completion": "Any person meeting the suspect case definition criteria with an epidemiological link."}, {"prompt": "What is the standard case definition for a confirmed case of Yellow Fever Disease?", "completion": "A probable case AND any person who meets the suspect or probable case definition criteria AND has not had yellow fever immunization within 30 days before the onset of illness; and one of the following: 1. Detection of yellow fever-specific IgM; 2. Detection of fourfold increase in yellow-fever IgM, or IgG antibody titres between acute and convalescent serum samples, or both; 3. Detection of yellow fever-specific neutralizing antibodies. YF-specific means that antibody tests (such as IgM or neutralizing antibody) for other prevalent flavivirus are negative. This testing should include at least IgM for Dengue and West Nile and may include other flavivirus depending on local epidemiology. OR Any person who meets the suspect or probable case definition criteria and has not had yellow fever immunization within 14 days before the onset of illness; and one of the following: 1. Detection of yellow fever virus genome in blood or other organs by PCR; 2. Detection of yellow fever antigen in blood, liver or other organs by immunoassay; 3. Isolation of yellow-fever virus."}, {"prompt": "How can health professionals confirm a case of Yellow Fever Disease?", "completion": "A probable case AND any person who meets the suspect or probable case definition criteria AND has not had yellow fever immunization within 30 days before the onset of illness; and one of the following: 1. Detection of yellow fever-specific IgM; 2. Detection of fourfold increase in yellow-fever IgM, or IgG antibody titres between acute and convalescent serum samples, or both; 3. Detection of yellow fever-specific neutralizing antibodies. YF-specific means that antibody tests (such as IgM or neutralizing antibody) for other prevalent flavivirus are negative. This testing should include at least IgM for Dengue and West Nile and may include other flavivirus depending on local epidemiology. OR Any person who meets the suspect or probable case definition criteria and has not had yellow fever immunization within 14 days before the onset of illness; and one of the following: 1. Detection of yellow fever virus genome in blood or other organs by PCR; 2. Detection of yellow fever antigen in blood, liver or other organs by immunoassay; 3. Isolation of yellow-fever virus."}, {"prompt": "What laboratory tests are used to confirm Yellow Fever Disease?", "completion": "A probable case AND any person who meets the suspect or probable case definition criteria AND has not had yellow fever immunization within 30 days before the onset of illness; and one of the following: 1. Detection of yellow fever-specific IgM; 2. Detection of fourfold increase in yellow-fever IgM, or IgG antibody titres between acute and convalescent serum samples, or both; 3. Detection of yellow fever-specific neutralizing antibodies. YF-specific means that antibody tests (such as IgM or neutralizing antibody) for other prevalent flavivirus are negative. This testing should include at least IgM for Dengue and West Nile and may include other flavivirus depending on local epidemiology. OR Any person who meets the suspect or probable case definition criteria and has not had yellow fever immunization within 14 days before the onset of illness; and one of the following: 1. Detection of yellow fever virus genome in blood or other organs by PCR; 2. Detection of yellow fever antigen in blood, liver or other organs by immunoassay; 3. Isolation of yellow-fever virus."}, {"prompt": "What is the process of confirming a case of Yellow Fever Disease?", "completion": "A probable case AND any person who meets the suspect or probable case definition criteria AND has not had yellow fever immunization within 30 days before the onset of illness; and one of the following: 1. Detection of yellow fever-specific IgM; 2. Detection of fourfold increase in yellow-fever IgM, or IgG antibody titres between acute and convalescent serum samples, or both; 3. Detection of yellow fever-specific neutralizing antibodies. YF-specific means that antibody tests (such as IgM or neutralizing antibody) for other prevalent flavivirus are negative. This testing should include at least IgM for Dengue and West Nile and may include other flavivirus depending on local epidemiology. OR Any person who meets the suspect or probable case definition criteria and has not had yellow fever immunization within 14 days before the onset of illness; and one of the following: 1. Detection of yellow fever virus genome in blood or other organs by PCR; 2. Detection of yellow fever antigen in blood, liver or other organs by immunoassay; 3. Isolation of yellow-fever virus."}, {"prompt": "When should an alert be raised for Yellow Fever Disease?", "completion": "If a single case or cluster is suspected or probable: Fill out a notification form, including clinical information, case-based forms, check vaccination status, and travel history. Take a blood specimen for laboratory confirmation. You may obtain convalescent specimens from patient(s). Diagnose and treat patient(s) with supportive care. Notify immediately to the next level. In the case of a probable case, inform nearby health units. Strengthen surveillance (apply the community case definition, i.e., fever and jaundice). Initiate a preliminary field investigation if a cluster of cases with fever and jaundice. Obtain information to determine the probable site of infection. Determine vaccination coverage of the community and start planning for vaccination (in case of a cluster)."}, {"prompt": "What are the initial steps when a Yellow Fever Disease case is suspected?", "completion": "If a single case or cluster is suspected or probable: Fill out a notification form, including clinical information, case-based forms, check vaccination status, and travel history. Take a blood specimen for laboratory confirmation. You may obtain convalescent specimens from patient(s). Diagnose and treat patient(s) with supportive care. Notify immediately to the next level. In the case of a probable case, inform nearby health units. Strengthen surveillance (apply the community case definition, i.e., fever and jaundice). Initiate a preliminary field investigation if a cluster of cases with fever and jaundice. Obtain information to determine the probable site of infection. Determine vaccination coverage of the community and start planning for vaccination (in case of a cluster)."}, {"prompt": "How do health authorities respond to a suspected Yellow Fever Disease case?", "completion": "If a single case or cluster is suspected or probable: Fill out a notification form, including clinical information, case-based forms, check vaccination status, and travel history. Take a blood specimen for laboratory confirmation. You may obtain convalescent specimens from patient(s). Diagnose and treat patient(s) with supportive care. Notify immediately to the next level. In the case of a probable case, inform nearby health units. Strengthen surveillance (apply the community case definition, i.e., fever and jaundice). Initiate a preliminary field investigation if a cluster of cases with fever and jaundice. Obtain information to determine the probable site of infection. Determine vaccination coverage of the community and start planning for vaccination (in case of a cluster)."}, {"prompt": "What actions should be taken at the community level if Yellow Fever Disease is suspected?", "completion": "If a single case or cluster is suspected or probable: Fill out a notification form, including clinical information, case-based forms, check vaccination status, and travel history. Take a blood specimen for laboratory confirmation. You may obtain convalescent specimens from patient(s). Diagnose and treat patient(s) with supportive care. Notify immediately to the next level. In the case of a probable case, inform nearby health units. Strengthen surveillance (apply the community case definition, i.e., fever and jaundice). Initiate a preliminary field investigation if a cluster of cases with fever and jaundice. Obtain information to determine the probable site of infection. Determine vaccination coverage of the community and start planning for vaccination (in case of a cluster)."}, {"prompt": "What actions should be taken if there's a confirmed case of Yellow Fever Disease?", "completion": "In addition to the alert threshold response, continue / complete an epidemiological investigation, including screening for vaccination status. Initiate entomological investigation if indicated. Determine vaccination coverage in the affected area (routine EPI, recent outbreak responses, or preventive campaigns). Initiate social mobilization for interventions selected. Continue risk communication and action to reduce risk, including vector control if indicated. Initiate vaccination in affected villages, district or town/city based on epidemiological findings. Notify WHO through Central Authorities using IHR decision instrument. Continue to strengthen routine yellow fever immunization, especially for hard-to-reach areas."}, {"prompt": "What steps should be taken once a Yellow Fever Disease case is confirmed?", "completion": "In addition to the alert threshold response, continue / complete an epidemiological investigation, including screening for vaccination status. Initiate entomological investigation if indicated. Determine vaccination coverage in the affected area (routine EPI, recent outbreak responses, or preventive campaigns). Initiate social mobilization for interventions selected. Continue risk communication and action to reduce risk, including vector control if indicated. Initiate vaccination in affected villages, district or town/city based on epidemiological findings. Notify WHO through Central Authorities using IHR decision instrument. Continue to strengthen routine yellow fever immunization, especially for hard-to-reach areas."}, {"prompt": "What actions are taken at the local level upon confirmation of Yellow Fever Disease?", "completion": "In addition to the alert threshold response, continue / complete an epidemiological investigation, including screening for vaccination status. Initiate entomological investigation if indicated. Determine vaccination coverage in the affected area (routine EPI, recent outbreak responses, or preventive campaigns). Initiate social mobilization for interventions selected. Continue risk communication and action to reduce risk, including vector control if indicated. Initiate vaccination in affected villages, district or town/city based on epidemiological findings. Notify WHO through Central Authorities using IHR decision instrument. Continue to strengthen routine yellow fever immunization, especially for hard-to-reach areas."}, {"prompt": "How can health authorities manage a confirmed Yellow Fever Disease case?", "completion": "In addition to the alert threshold response, continue / complete an epidemiological investigation, including screening for vaccination status. Initiate entomological investigation if indicated. Determine vaccination coverage in the affected area (routine EPI, recent outbreak responses, or preventive campaigns). Initiate social mobilization for interventions selected. Continue risk communication and action to reduce risk, including vector control if indicated. Initiate vaccination in affected villages, district or town/city based on epidemiological findings. Notify WHO through Central Authorities using IHR decision instrument. Continue to strengthen routine yellow fever immunization, especially for hard-to-reach areas."}, {"prompt": "How should data about a person with Yellow Fever Disease be analyzed and interpreted?", "completion": "Report immediate case-based information for cases and deaths. Report summary totals weekly. During an outbreak, count cases and deaths daily as they occur, then weekly when the epidemic matures or ends. Analyze by person variables (age, sex, occupation.). Assess risk factors to improve prevention of sporadic outbreaks."}, {"prompt": "What methods are used to analyze and interpret data on Yellow Fever Disease cases?", "completion": "Report immediate case-based information for cases and deaths. Report summary totals weekly. During an outbreak, count cases and deaths daily as they occur, then weekly when the epidemic matures or ends. Analyze by person variables (age, sex, occupation.). Assess risk factors to improve prevention of sporadic outbreaks."}, {"prompt": "How can data on Yellow Fever Disease cases be used to improve prevention strategies?", "completion": "Report immediate case-based information for cases and deaths. Report summary totals weekly. During an outbreak, count cases and deaths daily as they occur, then weekly when the epidemic matures or ends. Analyze by person variables (age, sex, occupation.). Assess risk factors to improve prevention of sporadic outbreaks."}, {"prompt": "What are the insights gained from analyzing Yellow Fever Disease data?", "completion": "Report immediate case-based information for cases and deaths. Report summary totals weekly. During an outbreak, count cases and deaths daily as they occur, then weekly when the epidemic matures or ends. Analyze by person variables (age, sex, occupation.). Assess risk factors to improve prevention of sporadic outbreaks."}, {"prompt": "How should data about time in the context of Yellow Fever Disease be analyzed and interpreted?", "completion": "Generate Weekly Graphs of cases and deaths. During outbreaks, construct epidemic curves (to monitor daily then weekly trends)."}, {"prompt": "What tools can be used to visualize Yellow Fever Disease case trends over time?", "completion": "Generate Weekly Graphs of cases and deaths. During outbreaks, construct epidemic curves (to monitor daily then weekly trends)."}, {"prompt": "How can temporal patterns help in understanding Yellow Fever Disease outbreaks?", "completion": "Generate Weekly Graphs of cases and deaths. During outbreaks, construct epidemic curves (to monitor daily then weekly trends)."}, {"prompt": "What are the benefits of analyzing Yellow Fever Disease data over time?", "completion": "Generate Weekly Graphs of cases and deaths. During outbreaks, construct epidemic curves (to monitor daily then weekly trends)."}, {"prompt": "How should data about place in the context of Yellow Fever Disease be analyzed and interpreted?", "completion": "Plot location of case households and occupation with precise mapping."}, {"prompt": "What mapping techniques are used to analyze the geographical distribution of Yellow Fever Disease cases?", "completion": "Plot location of case households and occupation with precise mapping."}, {"prompt": "How can spatial analysis contribute to understanding Yellow Fever Disease transmission?", "completion": "Plot location of case households and occupation with precise mapping."}, {"prompt": "What are the advantages of geospatial analysis in studying Yellow Fever Disease outbreaks?", "completion": "Plot location of case households and occupation with precise mapping."}, {"prompt": "How is Yellow Fever Disease diagnosed in the laboratory?", "completion": "1. ELISA for the presence of yellow fever Specific IgM and IgG antibodies. 2. Exclusion of Dengue, West Nile virus and other locally prevalent flavivirus will be necessary for the confirmation of yellow fever. 3. PCR, YF specific seroneutralization, virus isolation or histopathology. Specimen required is serum in the acute and convalescent phases of the illness; In the event of death, postmortem liver specimen. Collect the specimen within 14 days of onset of the first symptoms. Collect specimens from at least the first to 10th suspected cases of yellow fever. Collect specimens from the last cases (based on epidemic curves) to decide on the end of the epidemic. Follow specific guidelines for preparation, storage, and transportation of the specimen to the laboratory. Laboratory results should be received within 7 days of the reception of the specimen in the laboratory."}, {"prompt": "What laboratory tests are conducted to diagnose Yellow Fever Disease?", "completion": "1. ELISA for the presence of yellow fever Specific IgM and IgG antibodies. 2. Exclusion of Dengue, West Nile virus and other locally prevalent flavivirus will be necessary for the confirmation of yellow fever. 3. PCR, YF specific seroneutralization, virus isolation or histopathology. Specimen required is serum in the acute and convalescent phases of the illness; In the event of death, postmortem liver specimen. Collect the specimen within 14 days of onset of the first symptoms. Collect specimens from at least the first to 10th suspected cases of yellow fever. Collect specimens from the last cases (based on epidemic curves) to decide on the end of the epidemic. Follow specific guidelines for preparation, storage, and transportation of the specimen to the laboratory. Laboratory results should be received within 7 days of the reception of the specimen in the laboratory."}, {"prompt": "What are the steps involved in Yellow Fever Disease laboratory diagnosis?", "completion": "1. ELISA for the presence of yellow fever Specific IgM and IgG antibodies. 2. Exclusion of Dengue, West Nile virus and other locally prevalent flavivirus will be necessary for the confirmation of yellow fever. 3. PCR, YF specific seroneutralization, virus isolation or histopathology. Specimen required is serum in the acute and convalescent phases of the illness; In the event of death, postmortem liver specimen. Collect the specimen within 14 days of onset of the first symptoms. Collect specimens from at least the first to 10th suspected cases of yellow fever. Collect specimens from the last cases (based on epidemic curves) to decide on the end of the epidemic. Follow specific guidelines for preparation, storage, and transportation of the specimen to the laboratory. Laboratory results should be received within 7 days of the reception of the specimen in the laboratory."}, {"prompt": "What precautions should be taken during Yellow Fever Disease laboratory testing?", "completion": "1. ELISA for the presence of yellow fever Specific IgM and IgG antibodies. 2. Exclusion of Dengue, West Nile virus and other locally prevalent flavivirus will be necessary for the confirmation of yellow fever. 3. PCR, YF specific seroneutralization, virus isolation or histopathology. Specimen required is serum in the acute and convalescent phases of the illness; In the event of death, postmortem liver specimen. Collect the specimen within 14 days of onset of the first symptoms. Collect specimens from at least the first to 10th suspected cases of yellow fever. Collect specimens from the last cases (based on epidemic curves) to decide on the end of the epidemic. Follow specific guidelines for preparation, storage, and transportation of the specimen to the laboratory. Laboratory results should be received within 7 days of the reception of the specimen in the laboratory."}, {"prompt": "What are the references for Yellow Fever Disease?", "completion": "1. District guidelines for yellow fever surveillance. WHO 1998 WHO/GPVI/EPI/98.09 2. The Control of Communicable Diseases Manual, 20th Edition. American Public Health Association. 3. The WHO guidelines for yellow fever laboratory diagnosis. WHO 2004 WHO/CDS/CPE/ GPC/2004.9 4. The practical guide for yellow fever vaccination campaigns in Africa. WHO 2009 WHO/IVB/09.11 5. The Weekly epidemiological record (WER) for yellow fever. WHO"}, {"prompt": "Where can I find more information about Yellow Fever Disease?", "completion": "1. District guidelines for yellow fever surveillance. WHO 1998 WHO/GPVI/EPI/98.09 2. The Control of Communicable Diseases Manual, 20th Edition. American Public Health Association. 3. The WHO guidelines for yellow fever laboratory diagnosis. WHO 2004 WHO/CDS/CPE/ GPC/2004.9 4. The practical guide for yellow fever vaccination campaigns in Africa. WHO 2009 WHO/IVB/09.11 5. The Weekly epidemiological record (WER) for yellow fever. WHO"}, {"prompt": "What is West Nile Fever? related to Yellow Fever Disease", "completion": "West Nile Fever is a febrile illness resulting from a mosquito-borne arbovirus in the Flavivirudae family. Serological evidence suggests that the infection is present throughout practically the entire African continent. West Nile Fever most likely emerged in Africa and is now found worldwide. Outbreaks occur in humans, birds, and horses. Very severe cases include signs of encephalitis, meningo-encephalitis, or meningitis. Symptoms include high fever, headache, neck stiffness, stupor, tremors, convulsions, flaccid paralysis, and coma."}, {"prompt": "Describe the symptoms of West Nile Fever. related to Yellow Fever Disease", "completion": "West Nile Fever is a febrile illness resulting from a mosquito-borne arbovirus in the Flavivirudae family. Serological evidence suggests that the infection is present throughout practically the entire African continent. West Nile Fever most likely emerged in Africa and is now found worldwide. Outbreaks occur in humans, birds, and horses. Very severe cases include signs of encephalitis, meningo-encephalitis, or meningitis. Symptoms include high fever, headache, neck stiffness, stupor, tremors, convulsions, flaccid paralysis, and coma."}, {"prompt": "What are the common signs of West Nile Fever? related to Yellow Fever Disease", "completion": "West Nile Fever is a febrile illness resulting from a mosquito-borne arbovirus in the Flavivirudae family. Serological evidence suggests that the infection is present throughout practically the entire African continent. West Nile Fever most likely emerged in Africa and is now found worldwide. Outbreaks occur in humans, birds, and horses. Very severe cases include signs of encephalitis, meningo-encephalitis, or meningitis. Symptoms include high fever, headache, neck stiffness, stupor, tremors, convulsions, flaccid paralysis, and coma."}, {"prompt": "Explain the transmission of West Nile Fever. related to Yellow Fever Disease", "completion": "West Nile Fever is a zoonotic disease transmitted from birds to humans and other animals through mosquito bites."}, {"prompt": "How is West Nile Fever spread to humans? related to Yellow Fever Disease", "completion": "West Nile Fever is a zoonotic disease transmitted from birds to humans and other animals through mosquito bites."}, {"prompt": "Why is West Nile Fever considered a priority? related to Yellow Fever Disease", "completion": "Most cases are mild and may not come to the attention of the health system. Patients seeking health care usually present with flu-like symptoms such as fever, headache, and body aches. Occasionally patients present with a skin rash on the neck, trunk, arms, or legs. The case fatality rate in patients with neurological involvement ranges from 4% to 14% and as high as 29% in elderly patients."}, {"prompt": "What makes West Nile Fever a significant health concern? related to Yellow Fever Disease", "completion": "Most cases are mild and may not come to the attention of the health system. Patients seeking health care usually present with flu-like symptoms such as fever, headache, and body aches. Occasionally patients present with a skin rash on the neck, trunk, arms, or legs. The case fatality rate in patients with neurological involvement ranges from 4% to 14% and as high as 29% in elderly patients."}, {"prompt": "Who is at risk of severe illness from West Nile Fever? related to Yellow Fever Disease", "completion": "People of all ages and conditions may be affected. However, those who are above age 50 years or who have had an organ transplant are at increased risk of severe illness."}, {"prompt": "Which population groups are at higher risk of severe West Nile Fever? related to Yellow Fever Disease", "completion": "People of all ages and conditions may be affected. However, those who are above age 50 years or who have had an organ transplant are at increased risk of severe illness."}, {"prompt": "What are the surveillance goals for West Nile Fever? related to Yellow Fever Disease", "completion": "Identify risk factors for infection and determine high-risk populations for targeted prevention activities. Identify geographic areas for targeted prevention and control activities. Identify the most severe cases for referral to hospitalized care."}, {"prompt": "What is the purpose of West Nile Fever surveillance? related to Yellow Fever Disease", "completion": "Identify risk factors for infection and determine high-risk populations for targeted prevention activities. Identify geographic areas for targeted prevention and control activities. Identify the most severe cases for referral to hospitalized care."}, {"prompt": "What is the standard case definition for a suspected new case of West Nile Fever? related to Yellow Fever Disease", "completion": "A hospitalized case of encephalitis due to an unknown cause."}, {"prompt": "Define the criteria for a suspected new case of West Nile Fever. related to Yellow Fever Disease", "completion": "A hospitalized case of encephalitis due to an unknown cause."}, {"prompt": "What is the standard case definition for a confirmed case of West Nile Fever? related to Yellow Fever Disease", "completion": "Confirmation of West Nile Fever is through laboratory diagnostics to identify WNV-specific IgM antibodies."}, {"prompt": "How is a confirmed case of West Nile Fever diagnosed? related to Yellow Fever Disease", "completion": "Confirmation of West Nile Fever is through laboratory diagnostics to identify WNV-specific IgM antibodies."}, {"prompt": "When should an alert be raised for West Nile Fever? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels. Treat and manage the patient with supportive care. Collect specimens safely to confirm the case."}, {"prompt": "Under what circumstances should an alert be raised for West Nile Fever? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels. Treat and manage the patient with supportive care. Collect specimens safely to confirm the case."}, {"prompt": "What actions should be taken if a single case of West Nile Fever is confirmed? related to Yellow Fever Disease", "completion": "Treat and manage the patient with supportive care, Mobilize the community through education to promote adoption of behaviors that reduce disease risk, such as protection against mosquito bites and reduction of mosquito breeding sites. Conduct community education on how WNV is transmitted and how to prevent being infected."}, {"prompt": "How can communities respond to a confirmed case of West Nile Fever? related to Yellow Fever Disease", "completion": "Treat and manage the patient with supportive care, Mobilize the community through education to promote adoption of behaviors that reduce disease risk, such as protection against mosquito bites and reduction of mosquito breeding sites. Conduct community education on how WNV is transmitted and how to prevent being infected."}, {"prompt": "How should data about a person with West Nile Fever be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths. During an outbreak, count and report cases and deaths. Analyze age and sex distribution. Assess risk factors immediately and consider the request for assistance to improve outbreak control."}, {"prompt": "What insights can be gained from analyzing West Nile Fever data? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths. During an outbreak, count and report cases and deaths. Analyze age and sex distribution. Assess risk factors immediately and consider the request for assistance to improve outbreak control."}, {"prompt": "How should data about time in the context of West Nile Fever be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Construct an epidemic curve during the outbreak."}, {"prompt": "What are the methods to analyze time-related data for West Nile Fever? related to Yellow Fever Disease", "completion": "Construct an epidemic curve during the outbreak."}, {"prompt": "How should data about place in the context of West Nile Fever be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the location of case residence and worksite."}, {"prompt": "What techniques are used to analyze the geographical distribution of West Nile Fever cases? related to Yellow Fever Disease", "completion": "Plot the location of case residence and worksite."}, {"prompt": "How can spatial analysis contribute to understanding West Nile Fever transmission? related to Yellow Fever Disease", "completion": "Plot the location of case residence and worksite."}, {"prompt": "What is the laboratory diagnosis process for West Nile Fever? related to Yellow Fever Disease", "completion": "Presence of IgM antibodies against West Nile Fever. Specimens required for ELISA: Whole blood, serum, or plasma; for PCR: Whole blood or blood clot, serum/plasma or tissue; for immunohistochemistry: Skin or tissue specimens from fatal cases. Collect specimens from the first suspected case. If more than one suspected case, collect until specimens have been collected from 5 to 10 suspected cases. Handle and transport specimens from suspected VHF patients with extreme caution. Wear protective clothing and use barrier precautions. For ELISA or PCR: Refrigerate serum or clot, Freeze (-20\u00b0C or colder) tissue specimens for virus isolation; For Immunohistochemistry: Fix skin snip specimen in formalin. Specimen can be stored up to 6 weeks. The specimen is not infectious once it is in formalin. Store at room temperature. Formalin-fixed specimens may be transported at room temperature. Diagnostic services for VHF are not routinely available. Advance arrangements are usually required for VHF diagnostic services. Contact the appropriate National authority or WHO."}, {"prompt": "What tests are conducted for the laboratory diagnosis of West Nile Fever? related to Yellow Fever Disease", "completion": "Presence of IgM antibodies against West Nile Fever. Specimens required for ELISA: Whole blood, serum, or plasma; for PCR: Whole blood or blood clot, serum/plasma or tissue; for immunohistochemistry: Skin or tissue specimens from fatal cases. Collect specimens from the first suspected case. If more than one suspected case, collect until specimens have been collected from 5 to 10 suspected cases. Handle and transport specimens from suspected VHF patients with extreme caution. Wear protective clothing and use barrier precautions. For ELISA or PCR: Refrigerate serum or clot, Freeze (-20\u00b0C or colder) tissue specimens for virus isolation; For Immunohistochemistry: Fix skin snip specimen in formalin. Specimen can be stored up to 6 weeks. The specimen is not infectious once it is in formalin. Store at room temperature. Formalin-fixed specimens may be transported at room temperature. Diagnostic services for VHF are not routinely available. Advance arrangements are usually required for VHF diagnostic services. Contact the appropriate National authority or WHO."}, {"prompt": "How is laboratory diagnosis of West Nile Fever conducted? related to Yellow Fever Disease", "completion": "Presence of IgM antibodies against West Nile Fever. Specimens required for ELISA: Whole blood, serum, or plasma; for PCR: Whole blood or blood clot, serum/plasma or tissue; for immunohistochemistry: Skin or tissue specimens from fatal cases. Collect specimens from the first suspected case. If more than one suspected case, collect until specimens have been collected from 5 to 10 suspected cases. Handle and transport specimens from suspected VHF patients with extreme caution. Wear protective clothing and use barrier precautions. For ELISA or PCR: Refrigerate serum or clot, Freeze (-20\u00b0C or colder) tissue specimens for virus isolation; For Immunohistochemistry: Fix skin snip specimen in formalin. Specimen can be stored up to 6 weeks. The specimen is not infectious once it is in formalin. Store at room temperature. Formalin-fixed specimens may be transported at room temperature. Diagnostic services for VHF are not routinely available. Advance arrangements are usually required for VHF diagnostic services. Contact the appropriate National authority or WHO."}, {"prompt": "What are the references for West Nile Fever? related to Yellow Fever Disease", "completion": "1. Global Alert and Response; West Nile Fever epidemic updates http://www.who.int/csr/don/archive/disease/west_nile_fever/en/.\n2. Pedro N. A and Boris Szyfres. Zoonoses and Communicable Diseases Common to Man and Animals. Third edition, Volume II. Chlamydioses, Rickettsioses, and Viroses, Part II: Viroses Pages 372-376. Pan American Health Organization, WHO.\n3. Epidemic/Epizootic West Nile Virus in the United States: Guidelines for Surveillance, Prevention and Control. http://www.cdc.gov/ncidod/dvbid/westnile/resources/wnv-guidelines-aug-2003.pdf.\n4. Infection Control for Viral Hemorrhagic Fevers in the African Health Care Setting WHO/EMC/ESR/98.2."}, {"prompt": "Where can I find more information about West Nile Fever? related to Yellow Fever Disease", "completion": "1. Global Alert and Response; West Nile Fever epidemic updates http://www.who.int/csr/don/archive/disease/west_nile_fever/en/.\n2. Pedro N. A and Boris Szyfres. Zoonoses and Communicable Diseases Common to Man and Animals. Third edition, Volume II. Chlamydioses, Rickettsioses, and Viroses, Part II: Viroses Pages 372-376. Pan American Health Organization, WHO.\n3. Epidemic/Epizootic West Nile Virus in the United States: Guidelines for Surveillance, Prevention and Control. http://www.cdc.gov/ncidod/dvbid/westnile/resources/wnv-guidelines-aug-2003.pdf.\n4. Infection Control for Viral Hemorrhagic Fevers in the African Health Care Setting WHO/EMC/ESR/98.2."}, {"prompt": "Define Typhoid fever. related to Yellow Fever Disease", "completion": "Typhoid fever is a bacterial disease, caused by Salmonella typhi. Symptoms usually develop 1-3 weeks after exposure, and may be mild or severe. They include high fever, malaise, headache, constipation or diarrhoea, rose-coloured spots on the chest, and enlarged spleen and liver. Healthy carrier state may follow acute illness."}, {"prompt": "Describe the symptoms of Typhoid fever. related to Yellow Fever Disease", "completion": "Typhoid fever is a bacterial disease, caused by Salmonella typhi. Symptoms usually develop 1-3 weeks after exposure, and may be mild or severe. They include high fever, malaise, headache, constipation or diarrhoea, rose-coloured spots on the chest, and enlarged spleen and liver. Healthy carrier state may follow acute illness."}, {"prompt": "What are the common signs of Typhoid fever? related to Yellow Fever Disease", "completion": "Typhoid fever is a bacterial disease, caused by Salmonella typhi. Symptoms usually develop 1-3 weeks after exposure, and may be mild or severe. They include high fever, malaise, headache, constipation or diarrhoea, rose-coloured spots on the chest, and enlarged spleen and liver. Healthy carrier state may follow acute illness."}, {"prompt": "What makes Typhoid fever a significant health concern? related to Yellow Fever Disease", "completion": "Typhoid fever remains a serious public health problem throughout the world, with an estimated 16-33 million cases and 500,000 to 600,000 deaths annually. In the last outbreak in the Democratic Republic of Congo, between 27 September 2004 and early January 2005, no less than 42,564 cases of typhoid fever were reported, including 214 deaths and 696 cases of peritonitis and intestinal perforations. In virtually all endemic areas, the incidence of typhoid fever is highest in children from 5-19 years old."}, {"prompt": "Why is Typhoid fever a priority in public health? related to Yellow Fever Disease", "completion": "Typhoid fever remains a serious public health problem throughout the world, with an estimated 16-33 million cases and 500,000 to 600,000 deaths annually. In the last outbreak in the Democratic Republic of Congo, between 27 September 2004 and early January 2005, no less than 42,564 cases of typhoid fever were reported, including 214 deaths and 696 cases of peritonitis and intestinal perforations. In virtually all endemic areas, the incidence of typhoid fever is highest in children from 5-19 years old."}, {"prompt": "What are the objectives of Typhoid fever surveillance? related to Yellow Fever Disease", "completion": "Detect Typhoid Fever sporadic cases and outbreaks promptly, and seek laboratory verification. Identify areas/population at high risk to improve prevention of the disease by taking hygienic measures."}, {"prompt": "What is the purpose of Typhoid fever surveillance? related to Yellow Fever Disease", "completion": "Detect Typhoid Fever sporadic cases and outbreaks promptly, and seek laboratory verification. Identify areas/population at high risk to improve prevention of the disease by taking hygienic measures."}, {"prompt": "What is the standard case definition for a suspected new case of Typhoid fever? related to Yellow Fever Disease", "completion": "Any person with gradual onset of steadily increasing and then persistently high fever, chills, malaise, headache, sore throat, cough, and, sometimes, abdominal pain and constipation or diarrhoea."}, {"prompt": "What are the criteria for identifying a suspected new case of Typhoid fever? related to Yellow Fever Disease", "completion": "Any person with gradual onset of steadily increasing and then persistently high fever, chills, malaise, headache, sore throat, cough, and, sometimes, abdominal pain and constipation or diarrhoea."}, {"prompt": "What is the standard case definition for a confirmed case of Typhoid fever? related to Yellow Fever Disease", "completion": "Suspected case confirmed by isolation of Salmonella typhi from blood, bone marrow, bowel fluid or stool."}, {"prompt": "How is a confirmed case of Typhoid fever diagnosed? related to Yellow Fever Disease", "completion": "Suspected case confirmed by isolation of Salmonella typhi from blood, bone marrow, bowel fluid or stool."}, {"prompt": "When should an alert be raised for Typhoid fever? related to Yellow Fever Disease", "completion": "If Typhoid fever cases are suspected: Arrange for laboratory testing of stool specimens or rectal swabs of suspected cases, especially in situations where food- or waterborne transmission is suspected. Report and investigate all suspected outbreaks of typhoid. Search for case/carrier that is the source of infection and for the vehicle (water or food) through which infection is being transmitted. Treat typhoid fever patients with antibiotics. Severe cases should be provided supportive measures such as oral or intravenous hydration, the use of antipyretics, and appropriate nutrition."}, {"prompt": "Under what circumstances should an alert be raised for Typhoid fever? related to Yellow Fever Disease", "completion": "If Typhoid fever cases are suspected: Arrange for laboratory testing of stool specimens or rectal swabs of suspected cases, especially in situations where food- or waterborne transmission is suspected. Report and investigate all suspected outbreaks of typhoid. Search for case/carrier that is the source of infection and for the vehicle (water or food) through which infection is being transmitted. Treat typhoid fever patients with antibiotics. Severe cases should be provided supportive measures such as oral or intravenous hydration, the use of antipyretics, and appropriate nutrition."}, {"prompt": "What actions should be taken if there's an unusual increase in Typhoid fever cases? related to Yellow Fever Disease", "completion": "If Typhoid Fever cases are confirmed: Identify areas/populations at high risk to identify source(s) and mode(s) of transmission in order to prevent and control the disease. Conduct health education programmes on hygiene with simple messages on safe water, safe food handling practices, hygiene and hand washing. Support provision of clean water and proper sanitation to affected population(s). Chlorinate suspected water supplies. All drinking water should be chlorinated or boiled before use. More than 90% of patients can be managed at home with oral antibiotics, reliable care and close medical follow-up for complications or failure to respond to therapy. Patients with persistent vomiting, severe diarrhoea and abdominal distension may require hospitalization and parenteral antibiotic therapy."}, {"prompt": "How can communities respond to an increase in Typhoid fever cases? related to Yellow Fever Disease", "completion": "If Typhoid Fever cases are confirmed: Identify areas/populations at high risk to identify source(s) and mode(s) of transmission in order to prevent and control the disease. Conduct health education programmes on hygiene with simple messages on safe water, safe food handling practices, hygiene and hand washing. Support provision of clean water and proper sanitation to affected population(s). Chlorinate suspected water supplies. All drinking water should be chlorinated or boiled before use. More than 90% of patients can be managed at home with oral antibiotics, reliable care and close medical follow-up for complications or failure to respond to therapy. Patients with persistent vomiting, severe diarrhoea and abdominal distension may require hospitalization and parenteral antibiotic therapy."}, {"prompt": "How should data about a person with Typhoid fever be analyzed? related to Yellow Fever Disease", "completion": "Report immediate case-based information for cases and deaths. Report summary totals monthly. During outbreak, count cases and deaths weekly. Analyze by age. Assess risk factors to improve prevention of outbreaks."}, {"prompt": "What are the steps involved in analyzing data about a person with Typhoid fever? related to Yellow Fever Disease", "completion": "Report immediate case-based information for cases and deaths. Report summary totals monthly. During outbreak, count cases and deaths weekly. Analyze by age. Assess risk factors to improve prevention of outbreaks."}, {"prompt": "How should data about time in the context of Typhoid fever be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "What are the methods used to analyze the temporal pattern of Typhoid fever cases? related to Yellow Fever Disease", "completion": "Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "How should data about place in the context of Typhoid fever be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot location of case households with precise mapping."}, {"prompt": "What are the techniques used for spatial analysis of Typhoid fever cases? related to Yellow Fever Disease", "completion": "Plot location of case households with precise mapping."}, {"prompt": "How can spatial analysis contribute to understanding Typhoid fever transmission? related to Yellow Fever Disease", "completion": "Plot location of case households with precise mapping."}, {"prompt": "How is Typhoid fever diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Culture: Isolation of Salmonella spp. from stool or blood of a patient. The WIDAL Test should not be used for diagnostic purposes. Specimen required is Blood or Stool. Collected samples preferably before antibiotics are administered. Store specimens at 4-8\u00b0C or ambient temperature away from heat and direct sunlight. Results: Blood culture 4 days to 2 weeks; Stool 3-4 days."}, {"prompt": "What are the diagnostic procedures for Typhoid fever? related to Yellow Fever Disease", "completion": "Culture: Isolation of Salmonella spp. from stool or blood of a patient. The WIDAL Test should not be used for diagnostic purposes. Specimen required is Blood or Stool. Collected samples preferably before antibiotics are administered. Store specimens at 4-8\u00b0C or ambient temperature away from heat and direct sunlight. Results: Blood culture 4 days to 2 weeks; Stool 3-4 days."}, {"prompt": "What are the references for Typhoid fever? related to Yellow Fever Disease", "completion": "The diagnosis, Treatment and Prevention of Typhoid Fever; WHO/V&B/03.07; Weekly Epidemiological Record; N\u00b0 1, 2005, 80, 1-8; http//www.who.int/wer; WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2"}, {"prompt": "Where can I find more information about Typhoid fever? related to Yellow Fever Disease", "completion": "The diagnosis, Treatment and Prevention of Typhoid Fever; WHO/V&B/03.07; Weekly Epidemiological Record; N\u00b0 1, 2005, 80, 1-8; http//www.who.int/wer; WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2"}, {"prompt": "Explain Tuberculosis. related to Yellow Fever Disease", "completion": "Clinically, the pulmonary form of the disease is more common than the extra-pulmonary form. The cardinal symptoms of pulmonary TB are chronic cough, weight loss, fever, loss of appetite and night sweats. Incubation period is approximately 1 to 3 months. Infection of the lungs and other organs is usually caused by Mycobacterium tuberculosis transmitted person-to-person by droplet infection through coughing, sneezing or spitting."}, {"prompt": "Describe Tuberculosis. related to Yellow Fever Disease", "completion": "Clinically, the pulmonary form of the disease is more common than the extra-pulmonary form. The cardinal symptoms of pulmonary TB are chronic cough, weight loss, fever, loss of appetite and night sweats. Incubation period is approximately 1 to 3 months. Infection of the lungs and other organs is usually caused by Mycobacterium tuberculosis transmitted person-to-person by droplet infection through coughing, sneezing or spitting."}, {"prompt": "Elaborate on Tuberculosis. related to Yellow Fever Disease", "completion": "Clinically, the pulmonary form of the disease is more common than the extra-pulmonary form. The cardinal symptoms of pulmonary TB are chronic cough, weight loss, fever, loss of appetite and night sweats. Incubation period is approximately 1 to 3 months. Infection of the lungs and other organs is usually caused by Mycobacterium tuberculosis transmitted person-to-person by droplet infection through coughing, sneezing or spitting."}, {"prompt": "Define Tuberculosis. related to Yellow Fever Disease", "completion": "Clinically, the pulmonary form of the disease is more common than the extra-pulmonary form. The cardinal symptoms of pulmonary TB are chronic cough, weight loss, fever, loss of appetite and night sweats. Incubation period is approximately 1 to 3 months. Infection of the lungs and other organs is usually caused by Mycobacterium tuberculosis transmitted person-to-person by droplet infection through coughing, sneezing or spitting."}, {"prompt": "What is the nature of Tuberculosis? related to Yellow Fever Disease", "completion": "Clinically, the pulmonary form of the disease is more common than the extra-pulmonary form. The cardinal symptoms of pulmonary TB are chronic cough, weight loss, fever, loss of appetite and night sweats. Incubation period is approximately 1 to 3 months. Infection of the lungs and other organs is usually caused by Mycobacterium tuberculosis transmitted person-to-person by droplet infection through coughing, sneezing or spitting."}, {"prompt": "Why is Tuberculosis a global health priority? related to Yellow Fever Disease", "completion": "Tuberculosis (TB) is a leading cause of infectious illness and death worldwide with over 8 million new cases and 3 million deaths per year. In African countries, approximately 1.6 million of the new cases and over 600,000 cases occur each year. It is also estimated that between 30 and 50% of all new TB cases detected are infected with HIV and 40% of all AIDS deaths are due to TB. The global HIV pandemic has been a major cause of increasing TB cases, especially in African countries."}, {"prompt": "What makes Tuberculosis a priority in global health efforts? related to Yellow Fever Disease", "completion": "Tuberculosis (TB) is a leading cause of infectious illness and death worldwide with over 8 million new cases and 3 million deaths per year. In African countries, approximately 1.6 million of the new cases and over 600,000 cases occur each year. It is also estimated that between 30 and 50% of all new TB cases detected are infected with HIV and 40% of all AIDS deaths are due to TB. The global HIV pandemic has been a major cause of increasing TB cases, especially in African countries."}, {"prompt": "What are the reasons behind Tuberculosis being a global health priority? related to Yellow Fever Disease", "completion": "Tuberculosis (TB) is a leading cause of infectious illness and death worldwide with over 8 million new cases and 3 million deaths per year. In African countries, approximately 1.6 million of the new cases and over 600,000 cases occur each year. It is also estimated that between 30 and 50% of all new TB cases detected are infected with HIV and 40% of all AIDS deaths are due to TB. The global HIV pandemic has been a major cause of increasing TB cases, especially in African countries."}, {"prompt": "Who is most vulnerable to Tuberculosis? related to Yellow Fever Disease", "completion": "Those who are at the highest risk of dying from TB include people with HIV/AIDS, malnutrition and other immuno-compromising conditions, the very young, and the very old."}, {"prompt": "Who are the individuals most susceptible to Tuberculosis? related to Yellow Fever Disease", "completion": "Those who are at the highest risk of dying from TB include people with HIV/AIDS, malnutrition and other immuno-compromising conditions, the very young, and the very old."}, {"prompt": "What groups of people are at the highest risk of Tuberculosis? related to Yellow Fever Disease", "completion": "Those who are at the highest risk of dying from TB include people with HIV/AIDS, malnutrition and other immuno-compromising conditions, the very young, and the very old."}, {"prompt": "What are the surveillance objectives for Tuberculosis? related to Yellow Fever Disease", "completion": "Early detection of persons with infectious lung disease to improve chances of clinical improvement and reduce transmission of TB. Improve the percentage of TB cases confirmed by microscopy."}, {"prompt": "What are the goals of Tuberculosis surveillance? related to Yellow Fever Disease", "completion": "Early detection of persons with infectious lung disease to improve chances of clinical improvement and reduce transmission of TB. Improve the percentage of TB cases confirmed by microscopy."}, {"prompt": "What are the surveillance targets for Tuberculosis? related to Yellow Fever Disease", "completion": "Early detection of persons with infectious lung disease to improve chances of clinical improvement and reduce transmission of TB. Improve the percentage of TB cases confirmed by microscopy."}, {"prompt": "What is the standard case definition for a suspected new case of Tuberculosis? related to Yellow Fever Disease", "completion": "Any person with a cough of 3 weeks or more."}, {"prompt": "When should a person be suspected to have Tuberculosis? related to Yellow Fever Disease", "completion": "Any person with a cough of 3 weeks or more."}, {"prompt": "What is the case definition for suspecting a new case of Tuberculosis? related to Yellow Fever Disease", "completion": "Any person with a cough of 3 weeks or more."}, {"prompt": "What is the standard case definition for a confirmed case of Tuberculosis? related to Yellow Fever Disease", "completion": "Smear-positive pulmonary TB: a) a suspected patient with at least 2 sputum specimens positive for acid-fast bacilli (AFB), or b) one sputum specimen positive for AFB by microscopy and radiographic abnormalities consistent with active PTB as determined by the treating medical officer, or c) one positive sputum smear by microscopy and one sputum specimen positive on culture for AFB. Smear negative PTB: a patient who fulfills certain criteria."}, {"prompt": "How is a confirmed case of Tuberculosis defined? related to Yellow Fever Disease", "completion": "Smear-positive pulmonary TB: a) a suspected patient with at least 2 sputum specimens positive for acid-fast bacilli (AFB), or b) one sputum specimen positive for AFB by microscopy and radiographic abnormalities consistent with active PTB as determined by the treating medical officer, or c) one positive sputum smear by microscopy and one sputum specimen positive on culture for AFB. Smear negative PTB: a patient who fulfills certain criteria."}, {"prompt": "What criteria are used to confirm a case of Tuberculosis? related to Yellow Fever Disease", "completion": "Smear-positive pulmonary TB: a) a suspected patient with at least 2 sputum specimens positive for acid-fast bacilli (AFB), or b) one sputum specimen positive for AFB by microscopy and radiographic abnormalities consistent with active PTB as determined by the treating medical officer, or c) one positive sputum smear by microscopy and one sputum specimen positive on culture for AFB. Smear negative PTB: a patient who fulfills certain criteria."}, {"prompt": "When should an alert be raised for Tuberculosis? related to Yellow Fever Disease", "completion": "If you observe that the number of cases or deaths is increasing over a period of time: Report the problem to the next level, or according to national guidelines. Treat individual cases with direct observation (DOTS) including a treatment supporter. Investigate the cause of the increase."}, {"prompt": "Under what circumstances should an alert be raised for Tuberculosis? related to Yellow Fever Disease", "completion": "If you observe that the number of cases or deaths is increasing over a period of time: Report the problem to the next level, or according to national guidelines. Treat individual cases with direct observation (DOTS) including a treatment supporter. Investigate the cause of the increase."}, {"prompt": "What actions should be taken if there's an unusual increase in Tuberculosis cases? related to Yellow Fever Disease", "completion": "If the number of cases or deaths increases to two times the number usually seen in a similar period in the past: Assess health worker performance with detection and treatment of smear-positive PTB and improve practices as needed. Conduct drug susceptibility tests to establish patterns of resistance."}, {"prompt": "What steps should be taken in response to an unusual increase in Tuberculosis cases? related to Yellow Fever Disease", "completion": "If the number of cases or deaths increases to two times the number usually seen in a similar period in the past: Assess health worker performance with detection and treatment of smear-positive PTB and improve practices as needed. Conduct drug susceptibility tests to establish patterns of resistance."}, {"prompt": "How should data about individuals with Tuberculosis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count monthly cases and deaths. Analyze age and sex distribution quarterly."}, {"prompt": "What are the methods used to analyze data about individuals with Tuberculosis? related to Yellow Fever Disease", "completion": "Count monthly cases and deaths. Analyze age and sex distribution quarterly."}, {"prompt": "How can we interpret the data on Tuberculosis cases and individuals? related to Yellow Fever Disease", "completion": "Count monthly cases and deaths. Analyze age and sex distribution quarterly."}, {"prompt": "How should data about time in the context of Tuberculosis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases and deaths monthly."}, {"prompt": "What are the techniques used for temporal analysis of Tuberculosis cases? related to Yellow Fever Disease", "completion": "Graph cases and deaths monthly."}, {"prompt": "How can temporal analysis help in understanding Tuberculosis trends? related to Yellow Fever Disease", "completion": "Graph cases and deaths monthly."}, {"prompt": "How should data about place in the context of Tuberculosis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot distribution of case households and workplaces."}, {"prompt": "What are the methods used for spatial analysis of Tuberculosis cases? related to Yellow Fever Disease", "completion": "Plot distribution of case households and workplaces."}, {"prompt": "How can spatial analysis contribute to understanding Tuberculosis transmission? related to Yellow Fever Disease", "completion": "Plot distribution of case households and workplaces."}, {"prompt": "What are the laboratory procedures for diagnosing Tuberculosis? related to Yellow Fever Disease", "completion": "Microscopy: Presence of acid fast bacillus (AFB) in Ziehl Neelsen (ZN) stained smears, Culture and identification, Drug susceptibility test. Specimen required is Deep-chest sputum or Aspirates. Collect sputum (not saliva) for direct smear microscopy and examine at least two stained specimens taken on different days. Results interpretation varies with the method."}, {"prompt": "How is Tuberculosis diagnosed using laboratory techniques? related to Yellow Fever Disease", "completion": "Microscopy: Presence of acid fast bacillus (AFB) in Ziehl Neelsen (ZN) stained smears, Culture and identification, Drug susceptibility test. Specimen required is Deep-chest sputum or Aspirates. Collect sputum (not saliva) for direct smear microscopy and examine at least two stained specimens taken on different days. Results interpretation varies with the method."}, {"prompt": "What are the references for Tuberculosis? related to Yellow Fever Disease", "completion": "1. Treatment of Tuberculosis: Guidelines for National Programs. WHO/TB/97.230.\n2. Policy Statement of Prevention Therapy Against TB in People Living with HIV; WHO/TB/98.255.\n3. Weekly Epidemiological Record; N\u00b0 1, 2005, 80, 1-8; http//www.who.int/wer; WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2"}, {"prompt": "Where can I find more information about Tuberculosis? related to Yellow Fever Disease", "completion": "1. Treatment of Tuberculosis: Guidelines for National Programs. WHO/TB/97.230.\n2. Policy Statement of Prevention Therapy Against TB in People Living with HIV; WHO/TB/98.255.\n3. Weekly Epidemiological Record; N\u00b0 1, 2005, 80, 1-8; http//www.who.int/wer; WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2"}, {"prompt": "Explain Trypanosomiasis. related to Yellow Fever Disease", "completion": "Trypanosomiasis is an infection of blood, lymphatics, and the central nervous system. It is endemic in over 30 African countries in West, Central, and East Africa and is particularly epidemic in places like the Democratic Republic of Congo, Angola, and other areas of civil conflict. In these regions, up to 80% of some village populations may be infected. Cattle are the major reservoir of Trypanosoma brucei rhodesiense, and humans are the major reservoir for T. b. gambiense. The incubation period is typically days to weeks with T. b. rhodesiense and months to years with T. b. gambiense infections."}, {"prompt": "What is the nature of Trypanosomiasis? related to Yellow Fever Disease", "completion": "Trypanosomiasis is an infection of blood, lymphatics, and the central nervous system. It is endemic in over 30 African countries in West, Central, and East Africa and is particularly epidemic in places like the Democratic Republic of Congo, Angola, and other areas of civil conflict. In these regions, up to 80% of some village populations may be infected. Cattle are the major reservoir of Trypanosoma brucei rhodesiense, and humans are the major reservoir for T. b. gambiense. The incubation period is typically days to weeks with T. b. rhodesiense and months to years with T. b. gambiense infections."}, {"prompt": "Describe Trypanosomiasis. related to Yellow Fever Disease", "completion": "Trypanosomiasis is an infection of blood, lymphatics, and the central nervous system. It is endemic in over 30 African countries in West, Central, and East Africa and is particularly epidemic in places like the Democratic Republic of Congo, Angola, and other areas of civil conflict. In these regions, up to 80% of some village populations may be infected. Cattle are the major reservoir of Trypanosoma brucei rhodesiense, and humans are the major reservoir for T. b. gambiense. The incubation period is typically days to weeks with T. b. rhodesiense and months to years with T. b. gambiense infections."}, {"prompt": "Elaborate on Trypanosomiasis. related to Yellow Fever Disease", "completion": "Trypanosomiasis is an infection of blood, lymphatics, and the central nervous system. It is endemic in over 30 African countries in West, Central, and East Africa and is particularly epidemic in places like the Democratic Republic of Congo, Angola, and other areas of civil conflict. In these regions, up to 80% of some village populations may be infected. Cattle are the major reservoir of Trypanosoma brucei rhodesiense, and humans are the major reservoir for T. b. gambiense. The incubation period is typically days to weeks with T. b. rhodesiense and months to years with T. b. gambiense infections."}, {"prompt": "Define Trypanosomiasis. related to Yellow Fever Disease", "completion": "Trypanosomiasis is an infection of blood, lymphatics, and the central nervous system. It is endemic in over 30 African countries in West, Central, and East Africa and is particularly epidemic in places like the Democratic Republic of Congo, Angola, and other areas of civil conflict. In these regions, up to 80% of some village populations may be infected. Cattle are the major reservoir of Trypanosoma brucei rhodesiense, and humans are the major reservoir for T. b. gambiense. The incubation period is typically days to weeks with T. b. rhodesiense and months to years with T. b. gambiense infections."}, {"prompt": "How is Trypanosomiasis transmitted? related to Yellow Fever Disease", "completion": "In Africa, it is caused by the protozoan Trypanosoma burcei rhodesiense and T. b. gambiense, which are transmitted by the bite of infected Glossina (tsetse) flies."}, {"prompt": "What are the modes of transmission for Trypanosomiasis? related to Yellow Fever Disease", "completion": "In Africa, it is caused by the protozoan Trypanosoma burcei rhodesiense and T. b. gambiense, which are transmitted by the bite of infected Glossina (tsetse) flies."}, {"prompt": "Explain the transmission of Trypanosomiasis. related to Yellow Fever Disease", "completion": "In Africa, it is caused by the protozoan Trypanosoma burcei rhodesiense and T. b. gambiense, which are transmitted by the bite of infected Glossina (tsetse) flies."}, {"prompt": "Why is Trypanosomiasis a global health priority? related to Yellow Fever Disease", "completion": "Without treatment, both forms of Trypanosomiasis are usually fatal."}, {"prompt": "What makes Trypanosomiasis a priority in global health efforts? related to Yellow Fever Disease", "completion": "Without treatment, both forms of Trypanosomiasis are usually fatal."}, {"prompt": "What are the reasons behind Trypanosomiasis being a global health priority? related to Yellow Fever Disease", "completion": "Without treatment, both forms of Trypanosomiasis are usually fatal."}, {"prompt": "Is there any additional information on Trypanosomiasis? related to Yellow Fever Disease", "completion": "Trypanosomiasis control strategies include human and cattle population surveys to treat infected persons and diminish cattle reservoirs, as well as tsetse fly habitat control, such as removal of bushes and tall grasses near villages and the use of residual insecticides. Conditions like Tuberculosis, malaria, bacterial meningitis, HIV/AIDS, and other central nervous system or systemic infections can produce similar clinical findings to Trypanosomiasis."}, {"prompt": "What other details should I know about Trypanosomiasis? related to Yellow Fever Disease", "completion": "Trypanosomiasis control strategies include human and cattle population surveys to treat infected persons and diminish cattle reservoirs, as well as tsetse fly habitat control, such as removal of bushes and tall grasses near villages and the use of residual insecticides. Conditions like Tuberculosis, malaria, bacterial meningitis, HIV/AIDS, and other central nervous system or systemic infections can produce similar clinical findings to Trypanosomiasis."}, {"prompt": "Provide additional information about Trypanosomiasis. related to Yellow Fever Disease", "completion": "Trypanosomiasis control strategies include human and cattle population surveys to treat infected persons and diminish cattle reservoirs, as well as tsetse fly habitat control, such as removal of bushes and tall grasses near villages and the use of residual insecticides. Conditions like Tuberculosis, malaria, bacterial meningitis, HIV/AIDS, and other central nervous system or systemic infections can produce similar clinical findings to Trypanosomiasis."}, {"prompt": "What are the primary goals of surveillance for Trypanosomiasis? related to Yellow Fever Disease", "completion": "The goals include increasing the percentage of cases confirmed by laboratory methods, using population-based surveys and serologic screening for active case finding in endemic areas, conducting human and cattle screening in trypanosomiasis-free areas, and monitoring the effectiveness of prevention activities."}, {"prompt": "What are the objectives of Trypanosomiasis surveillance? related to Yellow Fever Disease", "completion": "The goals include increasing the percentage of cases confirmed by laboratory methods, using population-based surveys and serologic screening for active case finding in endemic areas, conducting human and cattle screening in trypanosomiasis-free areas, and monitoring the effectiveness of prevention activities."}, {"prompt": "What is the standard case definition for Trypanosomiasis? related to Yellow Fever Disease", "completion": "A suspected case is defined as someone with early-stage symptoms like a painful chancre originating as a papule and then evolving into a nodule at the primary fly bite site. There may also be fever, intense headache, insomnia, painless lymphadenopathy, anemia, local edema, and rash. In the late stage, symptoms may include cachexia, somnolence, and central nervous system signs. A confirmed case is a suspected case confirmed by a card agglutination trypanosomal test (CATT) or by the isolation of trypanosomes in blood, lymph nodes, or cerebrospinal fluid."}, {"prompt": "What are the criteria for diagnosing Trypanosomiasis? related to Yellow Fever Disease", "completion": "A suspected case is defined as someone with early-stage symptoms like a painful chancre originating as a papule and then evolving into a nodule at the primary fly bite site. There may also be fever, intense headache, insomnia, painless lymphadenopathy, anemia, local edema, and rash. In the late stage, symptoms may include cachexia, somnolence, and central nervous system signs. A confirmed case is a suspected case confirmed by a card agglutination trypanosomal test (CATT) or by the isolation of trypanosomes in blood, lymph nodes, or cerebrospinal fluid."}, {"prompt": "How is a confirmed case of Trypanosomiasis defined? related to Yellow Fever Disease", "completion": "A suspected case is defined as someone with early-stage symptoms like a painful chancre originating as a papule and then evolving into a nodule at the primary fly bite site. There may also be fever, intense headache, insomnia, painless lymphadenopathy, anemia, local edema, and rash. In the late stage, symptoms may include cachexia, somnolence, and central nervous system signs. A confirmed case is a suspected case confirmed by a card agglutination trypanosomal test (CATT) or by the isolation of trypanosomes in blood, lymph nodes, or cerebrospinal fluid."}, {"prompt": "When should an alert be raised for Trypanosomiasis? related to Yellow Fever Disease", "completion": "Upon observing an increase in the number of cases or deaths over a specific period, it's essential to report the problem according to national guidelines. This includes treating individual suspected and confirmed cases with appropriate therapy in closely monitored settings, collecting specimens for laboratory confirmation, and investigating the cause of the increasing number of cases to identify prevention activity problems."}, {"prompt": "Under what circumstances should an alert be raised for Trypanosomiasis? related to Yellow Fever Disease", "completion": "Upon observing an increase in the number of cases or deaths over a specific period, it's essential to report the problem according to national guidelines. This includes treating individual suspected and confirmed cases with appropriate therapy in closely monitored settings, collecting specimens for laboratory confirmation, and investigating the cause of the increasing number of cases to identify prevention activity problems."}, {"prompt": "What public health actions are recommended for Trypanosomiasis? related to Yellow Fever Disease", "completion": "Upon observing an increase in the number of cases or deaths over a specific period, it's essential to report the problem according to national guidelines. This includes treating individual suspected and confirmed cases with appropriate therapy in closely monitored settings, collecting specimens for laboratory confirmation, and investigating the cause of the increasing number of cases to identify prevention activity problems."}, {"prompt": "How should data about a person with Trypanosomiasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count monthly cases and analyze age distribution."}, {"prompt": "What methods are used to analyze data about individuals with Trypanosomiasis? related to Yellow Fever Disease", "completion": "Count monthly cases and analyze age distribution."}, {"prompt": "How can we interpret the data on Trypanosomiasis cases and individuals? related to Yellow Fever Disease", "completion": "Count monthly cases and analyze age distribution."}, {"prompt": "How should data about time in the context of Trypanosomiasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph quarterly cases to monitor epidemiological trends."}, {"prompt": "What are the techniques used for temporal analysis of Trypanosomiasis cases? related to Yellow Fever Disease", "completion": "Graph quarterly cases to monitor epidemiological trends."}, {"prompt": "How can temporal analysis help in understanding Trypanosomiasis trends? related to Yellow Fever Disease", "completion": "Graph quarterly cases to monitor epidemiological trends."}, {"prompt": "How should data about place in the context of Trypanosomiasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the distribution of case households."}, {"prompt": "What are the methods used for spatial analysis of Trypanosomiasis cases? related to Yellow Fever Disease", "completion": "Plot the distribution of case households."}, {"prompt": "How can spatial analysis contribute to understanding Trypanosomiasis transmission? related to Yellow Fever Disease", "completion": "Plot the distribution of case households."}, {"prompt": "How is Trypanosomiasis diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "While routine laboratory confirmation for surveillance is not required, a presumptive diagnosis can be made using a serological card agglutination trypanosomiasis test (CATT). Confirmation is through parasitological methods, specifically the detection of trypanosomes in blood, lymph node aspirates, or cerebrospinal fluid using microscopy."}, {"prompt": "What are the laboratory procedures for diagnosing Trypanosomiasis? related to Yellow Fever Disease", "completion": "While routine laboratory confirmation for surveillance is not required, a presumptive diagnosis can be made using a serological card agglutination trypanosomiasis test (CATT). Confirmation is through parasitological methods, specifically the detection of trypanosomes in blood, lymph node aspirates, or cerebrospinal fluid using microscopy."}, {"prompt": "How is Trypanosomiasis diagnosed using laboratory techniques? related to Yellow Fever Disease", "completion": "While routine laboratory confirmation for surveillance is not required, a presumptive diagnosis can be made using a serological card agglutination trypanosomiasis test (CATT). Confirmation is through parasitological methods, specifically the detection of trypanosomes in blood, lymph node aspirates, or cerebrospinal fluid using microscopy."}, {"prompt": "What are the references for Trypanosomiasis? related to Yellow Fever Disease", "completion": "1. Control and Surveillance of African Trypanosomiasis. Report of a WHO Expert Committee, Geneva, World Health Organization, 1998 (WHO Technical Report Series, No. 881); 2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2."}, {"prompt": "Where can I find more information about Trypanosomiasis? related to Yellow Fever Disease", "completion": "1. Control and Surveillance of African Trypanosomiasis. Report of a WHO Expert Committee, Geneva, World Health Organization, 1998 (WHO Technical Report Series, No. 881); 2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2."}, {"prompt": "What sources can I refer to for more details about Trypanosomiasis? related to Yellow Fever Disease", "completion": "1. Control and Surveillance of African Trypanosomiasis. Report of a WHO Expert Committee, Geneva, World Health Organization, 1998 (WHO Technical Report Series, No. 881); 2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2."}, {"prompt": "Explain Trachoma. related to Yellow Fever Disease", "completion": "Trachoma is the leading cause of preventable blindness worldwide. It is caused by infection with Chlamydia trachomatis bacteria, and is both treatable and preventable. Infections often begin during infancy or childhood and can become chronic. If left untreated, the infection eventually causes the eyelid to turn inwards, which in turn causes the eyelashes to rub on the eyeball, resulting in intense pain and scarring of the front of the eye. This ultimately leads to irreversible blindness, typically between 30 and 40 years of age."}, {"prompt": "Describe Trachoma. related to Yellow Fever Disease", "completion": "Trachoma is the leading cause of preventable blindness worldwide. It is caused by infection with Chlamydia trachomatis bacteria, and is both treatable and preventable. Infections often begin during infancy or childhood and can become chronic. If left untreated, the infection eventually causes the eyelid to turn inwards, which in turn causes the eyelashes to rub on the eyeball, resulting in intense pain and scarring of the front of the eye. This ultimately leads to irreversible blindness, typically between 30 and 40 years of age."}, {"prompt": "Elaborate on Trachoma. related to Yellow Fever Disease", "completion": "Trachoma is the leading cause of preventable blindness worldwide. It is caused by infection with Chlamydia trachomatis bacteria, and is both treatable and preventable. Infections often begin during infancy or childhood and can become chronic. If left untreated, the infection eventually causes the eyelid to turn inwards, which in turn causes the eyelashes to rub on the eyeball, resulting in intense pain and scarring of the front of the eye. This ultimately leads to irreversible blindness, typically between 30 and 40 years of age."}, {"prompt": "Define Trachoma. related to Yellow Fever Disease", "completion": "Trachoma is the leading cause of preventable blindness worldwide. It is caused by infection with Chlamydia trachomatis bacteria, and is both treatable and preventable. Infections often begin during infancy or childhood and can become chronic. If left untreated, the infection eventually causes the eyelid to turn inwards, which in turn causes the eyelashes to rub on the eyeball, resulting in intense pain and scarring of the front of the eye. This ultimately leads to irreversible blindness, typically between 30 and 40 years of age."}, {"prompt": "What is the nature of Trachoma? related to Yellow Fever Disease", "completion": "Trachoma is the leading cause of preventable blindness worldwide. It is caused by infection with Chlamydia trachomatis bacteria, and is both treatable and preventable. Infections often begin during infancy or childhood and can become chronic. If left untreated, the infection eventually causes the eyelid to turn inwards, which in turn causes the eyelashes to rub on the eyeball, resulting in intense pain and scarring of the front of the eye. This ultimately leads to irreversible blindness, typically between 30 and 40 years of age."}, {"prompt": "How is Trachoma transmitted? related to Yellow Fever Disease", "completion": "Trachoma is easily spread through direct personal contact, shared towels and cloths, and flies that have come in contact with the eyes or nose of an infected person."}, {"prompt": "What are the modes of transmission for Trachoma? related to Yellow Fever Disease", "completion": "Trachoma is easily spread through direct personal contact, shared towels and cloths, and flies that have come in contact with the eyes or nose of an infected person."}, {"prompt": "How can Trachoma be transmitted? related to Yellow Fever Disease", "completion": "Trachoma is easily spread through direct personal contact, shared towels and cloths, and flies that have come in contact with the eyes or nose of an infected person."}, {"prompt": "Why is Trachoma a global health priority? related to Yellow Fever Disease", "completion": "WHO estimates that approximately 6 million cases of blindness due to trachoma and 11 million cases of trichiasis occur worldwide each year. Prevalence of active disease in children varies from 10-40% in some African countries."}, {"prompt": "What makes Trachoma a priority in global health efforts? related to Yellow Fever Disease", "completion": "WHO estimates that approximately 6 million cases of blindness due to trachoma and 11 million cases of trichiasis occur worldwide each year. Prevalence of active disease in children varies from 10-40% in some African countries."}, {"prompt": "What are the reasons behind Trachoma being a global health priority? related to Yellow Fever Disease", "completion": "WHO estimates that approximately 6 million cases of blindness due to trachoma and 11 million cases of trichiasis occur worldwide each year. Prevalence of active disease in children varies from 10-40% in some African countries."}, {"prompt": "Is there any additional information on Trachoma? related to Yellow Fever Disease", "completion": "The infection primarily affects young children, with blindness occurring later in life. Females are three times more likely than males to suffer from trichiasis, the in-turning of the eyelashes that can lead to blindness. People are most at risk for trachoma infection in areas where there is poor sanitation, lack of latrines, poor sources of clean water, and the presence of flies. Primary interventions advocated for preventing trachoma infection include improved sanitation, reduction of fly breeding sites and increased facial cleanliness (with clean water) among children at risk of disease. The scaring and visual change for trachoma can be reversed by a simple surgical procedure performed at village level."}, {"prompt": "What are the additional details about Trachoma? related to Yellow Fever Disease", "completion": "The infection primarily affects young children, with blindness occurring later in life. Females are three times more likely than males to suffer from trichiasis, the in-turning of the eyelashes that can lead to blindness. People are most at risk for trachoma infection in areas where there is poor sanitation, lack of latrines, poor sources of clean water, and the presence of flies. Primary interventions advocated for preventing trachoma infection include improved sanitation, reduction of fly breeding sites and increased facial cleanliness (with clean water) among children at risk of disease. The scaring and visual change for trachoma can be reversed by a simple surgical procedure performed at village level."}, {"prompt": "What are the surveillance objectives for Trachoma? related to Yellow Fever Disease", "completion": "The goals include: Prevention of blindness by early detection. Identification of high risk areas and epidemiologic trends. Estimation of disease burden. Monitoring of control programs. Comparing surveillance data for Trachoma and other similar conditions."}, {"prompt": "What are the targets for Trachoma surveillance? related to Yellow Fever Disease", "completion": "The goals include: Prevention of blindness by early detection. Identification of high risk areas and epidemiologic trends. Estimation of disease burden. Monitoring of control programs. Comparing surveillance data for Trachoma and other similar conditions."}, {"prompt": "What actions are taken to achieve Trachoma surveillance goals? related to Yellow Fever Disease", "completion": "The goals include: Prevention of blindness by early detection. Identification of high risk areas and epidemiologic trends. Estimation of disease burden. Monitoring of control programs. Comparing surveillance data for Trachoma and other similar conditions."}, {"prompt": "What is the case definition for Trachoma? related to Yellow Fever Disease", "completion": "Suspected Case: Any patient with red sticky eyes who complains of pain and itchiness of the eyes. Confirmed Case: Any patient with red sticky eyes who complains of pain and itchiness of the eyes where examination of the eyes confirms one of the stages of Trachoma infection according to the WHO Simplified Trachoma Grading System."}, {"prompt": "How are Trachoma cases defined? related to Yellow Fever Disease", "completion": "Suspected Case: Any patient with red sticky eyes who complains of pain and itchiness of the eyes. Confirmed Case: Any patient with red sticky eyes who complains of pain and itchiness of the eyes where examination of the eyes confirms one of the stages of Trachoma infection according to the WHO Simplified Trachoma Grading System."}, {"prompt": "What are the criteria for defining Trachoma cases? related to Yellow Fever Disease", "completion": "Suspected Case: Any patient with red sticky eyes who complains of pain and itchiness of the eyes. Confirmed Case: Any patient with red sticky eyes who complains of pain and itchiness of the eyes where examination of the eyes confirms one of the stages of Trachoma infection according to the WHO Simplified Trachoma Grading System."}, {"prompt": "What public health measures are recommended for Trachoma? related to Yellow Fever Disease", "completion": "The World Health Organization has developed a series of interventions to control trachoma known by the acronym SAFE: Surgery, Antibiotics, Facial cleanliness, and Environmental improvement. Effective Trachoma control has four main components: Eye lid surgery for those at immediate risk of blindness. Antibiotics to treat individual cases and to reduce infection in a community. The promotion of facial cleanliness and hygiene to reduce transmission. Environmental improvements such as provision of water and household sanitation."}, {"prompt": "What actions are advised to address Trachoma from a public health perspective? related to Yellow Fever Disease", "completion": "The World Health Organization has developed a series of interventions to control trachoma known by the acronym SAFE: Surgery, Antibiotics, Facial cleanliness, and Environmental improvement. Effective Trachoma control has four main components: Eye lid surgery for those at immediate risk of blindness. Antibiotics to treat individual cases and to reduce infection in a community. The promotion of facial cleanliness and hygiene to reduce transmission. Environmental improvements such as provision of water and household sanitation."}, {"prompt": "What are the recommended public health interventions for Trachoma? related to Yellow Fever Disease", "completion": "The World Health Organization has developed a series of interventions to control trachoma known by the acronym SAFE: Surgery, Antibiotics, Facial cleanliness, and Environmental improvement. Effective Trachoma control has four main components: Eye lid surgery for those at immediate risk of blindness. Antibiotics to treat individual cases and to reduce infection in a community. The promotion of facial cleanliness and hygiene to reduce transmission. Environmental improvements such as provision of water and household sanitation."}, {"prompt": "How should data about individuals with Trachoma be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "What are the methods used to analyze data about individuals with Trachoma? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "What demographic factors are important in analyzing Trachoma data? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "How can data about time in the context of Trachoma be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Monitor epidemiologic trends over time."}, {"prompt": "What methods are used to analyze temporal data on Trachoma? related to Yellow Fever Disease", "completion": "Monitor epidemiologic trends over time."}, {"prompt": "How can trends in Trachoma cases be understood through temporal analysis? related to Yellow Fever Disease", "completion": "Monitor epidemiologic trends over time."}, {"prompt": "How should data about place in the context of Trachoma be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the location of case households and analyze the distribution."}, {"prompt": "What are the methods used for spatial analysis of Trachoma cases? related to Yellow Fever Disease", "completion": "Plot the location of case households and analyze the distribution."}, {"prompt": "How can spatial analysis contribute to understanding Trachoma transmission? related to Yellow Fever Disease", "completion": "Plot the location of case households and analyze the distribution."}, {"prompt": "How is Trachoma diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required. However, detection of specific antigen, nucleic acid tests, and tissue culture techniques can be used. Occasionally, in epithelial cells in Giemsa or iodine stained smears by direct microscopy can be used for diagnosis."}, {"prompt": "What are the laboratory methods for diagnosing Trachoma? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required. However, detection of specific antigen, nucleic acid tests, and tissue culture techniques can be used. Occasionally, in epithelial cells in Giemsa or iodine stained smears by direct microscopy can be used for diagnosis."}, {"prompt": "How is laboratory diagnosis of Trachoma performed? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required. However, detection of specific antigen, nucleic acid tests, and tissue culture techniques can be used. Occasionally, in epithelial cells in Giemsa or iodine stained smears by direct microscopy can be used for diagnosis."}, {"prompt": "What are the references for Trachoma? related to Yellow Fever Disease", "completion": "1. WHO Trachoma Page http://www.who.int/topics/trachoma/en/; 2. World Health Organization. Trachoma control: A guide for program managers. Geneva: World Health Organization, 2006; 3. World Health Organization. Achieving Community Support for Trachoma Control. Geneva: World Health Organization, 2006; 4. World Health Organization. Primary Health Care Level Management of trachoma. Geneva: World Health Organization, 2006; 5. World Health Organization. Trachoma epidemiologic survey protocol. Geneva: World Health Organization, 2006; 6. CDC Trachoma http://www.cdc.gov/healthywater/hygiene/disease/trachoma.html; 7. The Carter Center http://www.cartercenter.org/health/trachoma/index.html."}, {"prompt": "Where can I find more information about Trachoma? related to Yellow Fever Disease", "completion": "1. WHO Trachoma Page http://www.who.int/topics/trachoma/en/; 2. World Health Organization. Trachoma control: A guide for program managers. Geneva: World Health Organization, 2006; 3. World Health Organization. Achieving Community Support for Trachoma Control. Geneva: World Health Organization, 2006; 4. World Health Organization. Primary Health Care Level Management of trachoma. Geneva: World Health Organization, 2006; 5. World Health Organization. Trachoma epidemiologic survey protocol. Geneva: World Health Organization, 2006; 6. CDC Trachoma http://www.cdc.gov/healthywater/hygiene/disease/trachoma.html; 7. The Carter Center http://www.cartercenter.org/health/trachoma/index.html."}, {"prompt": "Can you provide references for Trachoma? related to Yellow Fever Disease", "completion": "1. WHO Trachoma Page http://www.who.int/topics/trachoma/en/; 2. World Health Organization. Trachoma control: A guide for program managers. Geneva: World Health Organization, 2006; 3. World Health Organization. Achieving Community Support for Trachoma Control. Geneva: World Health Organization, 2006; 4. World Health Organization. Primary Health Care Level Management of trachoma. Geneva: World Health Organization, 2006; 5. World Health Organization. Trachoma epidemiologic survey protocol. Geneva: World Health Organization, 2006; 6. CDC Trachoma http://www.cdc.gov/healthywater/hygiene/disease/trachoma.html; 7. The Carter Center http://www.cartercenter.org/health/trachoma/index.html."}, {"prompt": "What sources can I refer to for more information about Trachoma? related to Yellow Fever Disease", "completion": "1. WHO Trachoma Page http://www.who.int/topics/trachoma/en/; 2. World Health Organization. Trachoma control: A guide for program managers. Geneva: World Health Organization, 2006; 3. World Health Organization. Achieving Community Support for Trachoma Control. Geneva: World Health Organization, 2006; 4. World Health Organization. Primary Health Care Level Management of trachoma. Geneva: World Health Organization, 2006; 5. World Health Organization. Trachoma epidemiologic survey protocol. Geneva: World Health Organization, 2006; 6. CDC Trachoma http://www.cdc.gov/healthywater/hygiene/disease/trachoma.html; 7. The Carter Center http://www.cartercenter.org/health/trachoma/index.html."}, {"prompt": "Explain Sexually transmitted infections. related to Yellow Fever Disease", "completion": "The most common causes of male urethral discharge are a) the gonococcus Neisseria gonorrhoea and b) Chlamydia trachomatis. The most common causes of male and female genital ulcer are c) syphilis (Treponema pallidum), d) herpes simplex virus (HSV1 or 2) and e) chancroid (Haemophilus ducreyi)."}, {"prompt": "Describe Sexually transmitted infections. related to Yellow Fever Disease", "completion": "The most common causes of male urethral discharge are a) the gonococcus Neisseria gonorrhoea and b) Chlamydia trachomatis. The most common causes of male and female genital ulcer are c) syphilis (Treponema pallidum), d) herpes simplex virus (HSV1 or 2) and e) chancroid (Haemophilus ducreyi)."}, {"prompt": "Elaborate on Sexually transmitted infections. related to Yellow Fever Disease", "completion": "The most common causes of male urethral discharge are a) the gonococcus Neisseria gonorrhoea and b) Chlamydia trachomatis. The most common causes of male and female genital ulcer are c) syphilis (Treponema pallidum), d) herpes simplex virus (HSV1 or 2) and e) chancroid (Haemophilus ducreyi)."}, {"prompt": "Define Sexually transmitted infections. related to Yellow Fever Disease", "completion": "The most common causes of male urethral discharge are a) the gonococcus Neisseria gonorrhoea and b) Chlamydia trachomatis. The most common causes of male and female genital ulcer are c) syphilis (Treponema pallidum), d) herpes simplex virus (HSV1 or 2) and e) chancroid (Haemophilus ducreyi)."}, {"prompt": "What are Sexually transmitted diseases? related to Yellow Fever Disease", "completion": "The most common causes of male urethral discharge are a) the gonococcus Neisseria gonorrhoea and b) Chlamydia trachomatis. The most common causes of male and female genital ulcer are c) syphilis (Treponema pallidum), d) herpes simplex virus (HSV1 or 2) and e) chancroid (Haemophilus ducreyi)."}, {"prompt": "How are Sexually transmitted infections transmitted? related to Yellow Fever Disease", "completion": "Infections of the human genito-urinary and reproductive systems transmitted via human sexual contact (sexually transmitted disease, STIs)."}, {"prompt": "What are the modes of transmission for Sexually transmitted infections? related to Yellow Fever Disease", "completion": "Infections of the human genito-urinary and reproductive systems transmitted via human sexual contact (sexually transmitted disease, STIs)."}, {"prompt": "How do Sexually transmitted infections spread? related to Yellow Fever Disease", "completion": "Infections of the human genito-urinary and reproductive systems transmitted via human sexual contact (sexually transmitted disease, STIs)."}, {"prompt": "What are the reasons behind considering Sexually transmitted infections a priority? related to Yellow Fever Disease", "completion": "STIs are a leading cause of abortion and stillbirth, prematurity, and congenital infections. They may lead to pelvic inflammatory disease (PID), a major cause of decreased fertility. STIs may be most highly prevalent in areas where HIV occurs and may facilitate HIV transmission. STIs may be primary or from repeated attacks of urethral discharge."}, {"prompt": "Why are Sexually transmitted infections given priority in public health efforts? related to Yellow Fever Disease", "completion": "STIs are a leading cause of abortion and stillbirth, prematurity, and congenital infections. They may lead to pelvic inflammatory disease (PID), a major cause of decreased fertility. STIs may be most highly prevalent in areas where HIV occurs and may facilitate HIV transmission. STIs may be primary or from repeated attacks of urethral discharge."}, {"prompt": "What makes Sexually transmitted infections a public health priority? related to Yellow Fever Disease", "completion": "STIs are a leading cause of abortion and stillbirth, prematurity, and congenital infections. They may lead to pelvic inflammatory disease (PID), a major cause of decreased fertility. STIs may be most highly prevalent in areas where HIV occurs and may facilitate HIV transmission. STIs may be primary or from repeated attacks of urethral discharge."}, {"prompt": "Is there any additional information on Sexually transmitted infections? related to Yellow Fever Disease", "completion": "Incubation periods for gonorrhoea are 2 to 7 days; Chlamydia 7 to 14 days (or longer); syphilis, 10 days to 12 weeks (usually around 3 weeks), and chancroid, 3 to 14 days. STIs are endemic in most countries of the world, including countries in Africa. Multiple simultaneous STIs are common (for example, gonorrhoea plus Chlamydia)."}, {"prompt": "What are the additional details about Sexually transmitted infections? related to Yellow Fever Disease", "completion": "Incubation periods for gonorrhoea are 2 to 7 days; Chlamydia 7 to 14 days (or longer); syphilis, 10 days to 12 weeks (usually around 3 weeks), and chancroid, 3 to 14 days. STIs are endemic in most countries of the world, including countries in Africa. Multiple simultaneous STIs are common (for example, gonorrhoea plus Chlamydia)."}, {"prompt": "What are the surveillance objectives for Sexually transmitted infections? related to Yellow Fever Disease", "completion": "The goals include: Early detection and treatment of STI to reduce transmission rates. Active efforts to diagnose latent syphilis may prevent significant disability. Improvement of early and effective treatment of STIs using simple algorithms based on syndromic diagnosis for index cases and partners. Carrying out laboratory-based anti-microbial sensitivity monitoring and modifying treatment guidelines accordingly at the national level. Comparing surveillance data for both STIs and HIV/AIDS since STIs may reflect co-presence of HIV."}, {"prompt": "What are the aims of Sexually transmitted infections surveillance? related to Yellow Fever Disease", "completion": "The goals include: Early detection and treatment of STI to reduce transmission rates. Active efforts to diagnose latent syphilis may prevent significant disability. Improvement of early and effective treatment of STIs using simple algorithms based on syndromic diagnosis for index cases and partners. Carrying out laboratory-based anti-microbial sensitivity monitoring and modifying treatment guidelines accordingly at the national level. Comparing surveillance data for both STIs and HIV/AIDS since STIs may reflect co-presence of HIV."}, {"prompt": "What is the standard case definition for Sexually transmitted infections? related to Yellow Fever Disease", "completion": "Suspected Case: Genital ulcer syndrome (non-vesicular): Any male with an ulcer on the penis, scrotum, or rectum, with or without inguinal adenopathy, or any female with ulcer on labia, vagina, or rectum, with or without inguinal adenopathy. Urethral discharge syndrome: Any male with urethral discharge with or without dysuria. Confirmed Case: Urethral discharge syndrome: A suspected case confirmed by a laboratory method (for example Gram stain showing intracellular Gram-negative diplococci). Genital ulcer syndrome (non-vesicular): Any suspected case confirmed by a laboratory method."}, {"prompt": "What is the standard definition used for Sexually transmitted infections? related to Yellow Fever Disease", "completion": "Suspected Case: Genital ulcer syndrome (non-vesicular): Any male with an ulcer on the penis, scrotum, or rectum, with or without inguinal adenopathy, or any female with ulcer on labia, vagina, or rectum, with or without inguinal adenopathy. Urethral discharge syndrome: Any male with urethral discharge with or without dysuria. Confirmed Case: Urethral discharge syndrome: A suspected case confirmed by a laboratory method (for example Gram stain showing intracellular Gram-negative diplococci). Genital ulcer syndrome (non-vesicular): Any suspected case confirmed by a laboratory method."}, {"prompt": "How are confirmed cases of Sexually transmitted infections defined? related to Yellow Fever Disease", "completion": "Suspected Case: Genital ulcer syndrome (non-vesicular): Any male with an ulcer on the penis, scrotum, or rectum, with or without inguinal adenopathy, or any female with ulcer on labia, vagina, or rectum, with or without inguinal adenopathy. Urethral discharge syndrome: Any male with urethral discharge with or without dysuria. Confirmed Case: Urethral discharge syndrome: A suspected case confirmed by a laboratory method (for example Gram stain showing intracellular Gram-negative diplococci). Genital ulcer syndrome (non-vesicular): Any suspected case confirmed by a laboratory method."}, {"prompt": "When should an alert be raised for Sexually transmitted infections? related to Yellow Fever Disease", "completion": "If you observe that the number of cases or deaths is increasing over a period of time: Report the problem to the next level, or according to national guidelines. Treat individual cases with direct observation (DOTS) including a treatment supporter. Investigate the cause of the increase."}, {"prompt": "What are the circumstances that warrant raising an alert for Sexually transmitted infections? related to Yellow Fever Disease", "completion": "If you observe that the number of cases or deaths is increasing over a period of time: Report the problem to the next level, or according to national guidelines. Treat individual cases with direct observation (DOTS) including a treatment supporter. Investigate the cause of the increase."}, {"prompt": "What actions should be taken if there's an unusual increase in Sexually transmitted infections cases? related to Yellow Fever Disease", "completion": "If the number of cases or deaths increases to two times the number usually seen in a similar period in the past: Assess health worker performance with detection and treatment of smear-positive PTB and improve practices as needed. Conduct drug susceptibility tests to establish patterns of resistance."}, {"prompt": "What public health measures are recommended during an unusual increase in Sexually transmitted infections cases? related to Yellow Fever Disease", "completion": "If the number of cases or deaths increases to two times the number usually seen in a similar period in the past: Assess health worker performance with detection and treatment of smear-positive PTB and improve practices as needed. Conduct drug susceptibility tests to establish patterns of resistance."}, {"prompt": "What steps should be taken if there's an unusual increase in Sexually transmitted infections cases? related to Yellow Fever Disease", "completion": "If the number of cases or deaths increases to two times the number usually seen in a similar period in the past: Assess health worker performance with detection and treatment of smear-positive PTB and improve practices as needed. Conduct drug susceptibility tests to establish patterns of resistance."}, {"prompt": "How should data about individuals with Sexually transmitted infections be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count quarterly cases and analyze the age distribution of those infected."}, {"prompt": "What are the techniques for analyzing and interpreting data about individuals with Sexually transmitted infections? related to Yellow Fever Disease", "completion": "Count quarterly cases and analyze the age distribution of those infected."}, {"prompt": "How can we interpret the data on Sexually transmitted infections cases and individuals? related to Yellow Fever Disease", "completion": "Count quarterly cases and analyze the age distribution of those infected."}, {"prompt": "How should data about time in the context of Sexually transmitted infections be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Cases should be graphed each quarter to monitor trends and patterns over time."}, {"prompt": "What are the methods for temporal analysis of Sexually transmitted infections cases? related to Yellow Fever Disease", "completion": "Cases should be graphed each quarter to monitor trends and patterns over time."}, {"prompt": "How can temporal analysis contribute to understanding Sexually transmitted infections trends? related to Yellow Fever Disease", "completion": "Cases should be graphed each quarter to monitor trends and patterns over time."}, {"prompt": "What are the recommended methods for analyzing and interpreting data about place in the context of Sexually transmitted infections? related to Yellow Fever Disease", "completion": "There is no specific recommendation for the analysis of place in the context of STIs."}, {"prompt": "How can spatial analysis contribute to understanding Sexually transmitted infections transmission? related to Yellow Fever Disease", "completion": "There is no specific recommendation for the analysis of place in the context of STIs."}, {"prompt": "What are the laboratory procedures for diagnosing Sexually transmitted infections? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "What tests are used in the laboratory for diagnosing Sexually transmitted infections? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "What are the references for Sexually transmitted infections? related to Yellow Fever Disease", "completion": "1. Guidelines for Sexually Transmitted Infections Surveillance. Geneva. UNAIDS and World Health Organization. WHO/CDS/CSR/EDC/99.3. UNAIDS/99.33E"}, {"prompt": "Where can I find more information about Sexually transmitted infections? related to Yellow Fever Disease", "completion": "1. Guidelines for Sexually Transmitted Infections Surveillance. Geneva. UNAIDS and World Health Organization. WHO/CDS/CSR/EDC/99.3. UNAIDS/99.33E"}, {"prompt": "Define Smallpox (Variola). related to Yellow Fever Disease", "completion": "Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. Other members of the genus include cowpox, camelpox, and monkeypox. Monkeypox virus has caused the most serious recent human poxvirus infections. The disease has an incubation period followed by the sudden onset of influenza-like symptoms. Two to three days later, a characteristic rash appears, first on the face, hands, and forearms, and then progresses to the trunk. Lesions also develop in the mucous membranes of the nose and mouth. Lesions progress from macules to papules to vesicles to pustules. From 8 to 14 days after the onset of symptoms, the pustules form scabs which leave depressed depigmented scars upon healing."}, {"prompt": "Describe Smallpox (Variola). related to Yellow Fever Disease", "completion": "Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. Other members of the genus include cowpox, camelpox, and monkeypox. Monkeypox virus has caused the most serious recent human poxvirus infections. The disease has an incubation period followed by the sudden onset of influenza-like symptoms. Two to three days later, a characteristic rash appears, first on the face, hands, and forearms, and then progresses to the trunk. Lesions also develop in the mucous membranes of the nose and mouth. Lesions progress from macules to papules to vesicles to pustules. From 8 to 14 days after the onset of symptoms, the pustules form scabs which leave depressed depigmented scars upon healing."}, {"prompt": "Explain Smallpox (Variola). related to Yellow Fever Disease", "completion": "Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. Other members of the genus include cowpox, camelpox, and monkeypox. Monkeypox virus has caused the most serious recent human poxvirus infections. The disease has an incubation period followed by the sudden onset of influenza-like symptoms. Two to three days later, a characteristic rash appears, first on the face, hands, and forearms, and then progresses to the trunk. Lesions also develop in the mucous membranes of the nose and mouth. Lesions progress from macules to papules to vesicles to pustules. From 8 to 14 days after the onset of symptoms, the pustules form scabs which leave depressed depigmented scars upon healing."}, {"prompt": "Elaborate on Smallpox (Variola). related to Yellow Fever Disease", "completion": "Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. Other members of the genus include cowpox, camelpox, and monkeypox. Monkeypox virus has caused the most serious recent human poxvirus infections. The disease has an incubation period followed by the sudden onset of influenza-like symptoms. Two to three days later, a characteristic rash appears, first on the face, hands, and forearms, and then progresses to the trunk. Lesions also develop in the mucous membranes of the nose and mouth. Lesions progress from macules to papules to vesicles to pustules. From 8 to 14 days after the onset of symptoms, the pustules form scabs which leave depressed depigmented scars upon healing."}, {"prompt": "What is the nature of Smallpox (Variola)? related to Yellow Fever Disease", "completion": "Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. Other members of the genus include cowpox, camelpox, and monkeypox. Monkeypox virus has caused the most serious recent human poxvirus infections. The disease has an incubation period followed by the sudden onset of influenza-like symptoms. Two to three days later, a characteristic rash appears, first on the face, hands, and forearms, and then progresses to the trunk. Lesions also develop in the mucous membranes of the nose and mouth. Lesions progress from macules to papules to vesicles to pustules. From 8 to 14 days after the onset of symptoms, the pustules form scabs which leave depressed depigmented scars upon healing."}, {"prompt": "How is Smallpox (Variola) transmitted? related to Yellow Fever Disease", "completion": "Smallpox is transmitted from person to person by infected aerosols and air droplets spread in face-to-face contact with an infected person after the fever has begun, especially if symptoms include coughing. The disease can also be transmitted by contaminated clothes and bedding, though the risk from this source is much lower."}, {"prompt": "What are the modes of transmission of Smallpox (Variola)? related to Yellow Fever Disease", "completion": "Smallpox is transmitted from person to person by infected aerosols and air droplets spread in face-to-face contact with an infected person after the fever has begun, especially if symptoms include coughing. The disease can also be transmitted by contaminated clothes and bedding, though the risk from this source is much lower."}, {"prompt": "How does Smallpox (Variola) spread? related to Yellow Fever Disease", "completion": "Smallpox is transmitted from person to person by infected aerosols and air droplets spread in face-to-face contact with an infected person after the fever has begun, especially if symptoms include coughing. The disease can also be transmitted by contaminated clothes and bedding, though the risk from this source is much lower."}, {"prompt": "Why is Smallpox (Variola) a global health priority? related to Yellow Fever Disease", "completion": "Smallpox had two main forms: variola major and variola minor. The disease followed a milder course in variola minor, which had a case-fatality rate of less than 1 per cent. The fatality rate of variola major was around 30%. There are two rare forms of smallpox: haemorrhagic and malignant. Smallpox killed as many as 30% of those infected. In 1967, when WHO launched an intensified plan to eradicate smallpox, the disease threatened 60% of the world's population and killed every fourth patient."}, {"prompt": "What makes Smallpox (Variola) a global health priority? related to Yellow Fever Disease", "completion": "Smallpox had two main forms: variola major and variola minor. The disease followed a milder course in variola minor, which had a case-fatality rate of less than 1 per cent. The fatality rate of variola major was around 30%. There are two rare forms of smallpox: haemorrhagic and malignant. Smallpox killed as many as 30% of those infected. In 1967, when WHO launched an intensified plan to eradicate smallpox, the disease threatened 60% of the world's population and killed every fourth patient."}, {"prompt": "What are the characteristics that make Smallpox (Variola) a global health priority? related to Yellow Fever Disease", "completion": "Smallpox had two main forms: variola major and variola minor. The disease followed a milder course in variola minor, which had a case-fatality rate of less than 1 per cent. The fatality rate of variola major was around 30%. There are two rare forms of smallpox: haemorrhagic and malignant. Smallpox killed as many as 30% of those infected. In 1967, when WHO launched an intensified plan to eradicate smallpox, the disease threatened 60% of the world's population and killed every fourth patient."}, {"prompt": "Provide additional details about Smallpox (Variola). related to Yellow Fever Disease", "completion": "The incubation period of smallpox is usually 12-14 days, during which there is no evidence of viral shedding. During this period, the person looks and feels healthy and cannot infect others. Vaccine administered up to 4 days after exposure to the virus, and before the rash appears, provides protective immunity and can prevent infection or ameliorate the severity of the disease. Immediate Notification to WHO is formally required by IHR (2005)."}, {"prompt": "What other important information is there about Smallpox (Variola)? related to Yellow Fever Disease", "completion": "The incubation period of smallpox is usually 12-14 days, during which there is no evidence of viral shedding. During this period, the person looks and feels healthy and cannot infect others. Vaccine administered up to 4 days after exposure to the virus, and before the rash appears, provides protective immunity and can prevent infection or ameliorate the severity of the disease. Immediate Notification to WHO is formally required by IHR (2005)."}, {"prompt": "What are the surveillance objectives for Smallpox (Variola)? related to Yellow Fever Disease", "completion": "The goal is to detect and immediately respond to any suspected case of smallpox."}, {"prompt": "What are the goals of surveillance for Smallpox (Variola)? related to Yellow Fever Disease", "completion": "The goal is to detect and immediately respond to any suspected case of smallpox."}, {"prompt": "What is the primary aim of surveillance for Smallpox (Variola)? related to Yellow Fever Disease", "completion": "The goal is to detect and immediately respond to any suspected case of smallpox."}, {"prompt": "Define the standard case criteria for Smallpox (Variola). related to Yellow Fever Disease", "completion": "Suspected Case: An illness with acute onset of fever > 38.3 C (101 F) followed by a rash characterized by vesicles or firm pustules in the same stage of development without any other apparent cause. Probable Case: A case that meets the clinical case definition, is not laboratory confirmed, but has an epidemiological link to a confirmed or probable case. Confirmed Case: A clinically compatible case that is laboratory confirmed."}, {"prompt": "What are the criteria for a suspected case of Smallpox (Variola)? related to Yellow Fever Disease", "completion": "Suspected Case: An illness with acute onset of fever > 38.3 C (101 F) followed by a rash characterized by vesicles or firm pustules in the same stage of development without any other apparent cause. Probable Case: A case that meets the clinical case definition, is not laboratory confirmed, but has an epidemiological link to a confirmed or probable case. Confirmed Case: A clinically compatible case that is laboratory confirmed."}, {"prompt": "How is a suspected case of Smallpox (Variola) defined? related to Yellow Fever Disease", "completion": "Suspected Case: An illness with acute onset of fever > 38.3 C (101 F) followed by a rash characterized by vesicles or firm pustules in the same stage of development without any other apparent cause. Probable Case: A case that meets the clinical case definition, is not laboratory confirmed, but has an epidemiological link to a confirmed or probable case. Confirmed Case: A clinically compatible case that is laboratory confirmed."}, {"prompt": "What steps should be taken when an alert is raised for Smallpox (Variola)? related to Yellow Fever Disease", "completion": "If a single case is suspected, immediate actions include: Reporting the case to the appropriate levels, implementing airborne infection control precautions, treating and managing the patient with supportive care, collecting specimens safely to confirm the case, implementing contact tracing and contact management, conducting active surveillance to identify additional cases, and notifying WHO."}, {"prompt": "What actions are required when an alert is raised for Smallpox (Variola)? related to Yellow Fever Disease", "completion": "If a single case is suspected, immediate actions include: Reporting the case to the appropriate levels, implementing airborne infection control precautions, treating and managing the patient with supportive care, collecting specimens safely to confirm the case, implementing contact tracing and contact management, conducting active surveillance to identify additional cases, and notifying WHO."}, {"prompt": "How should data about an individual with Smallpox (Variola) be assessed? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths should be conducted. During the outbreak, cases and deaths should be counted and reported. The age and sex distribution of cases should be analyzed, and risk factors should be assessed immediately."}, {"prompt": "What is the process for analyzing and interpreting data about individuals with Smallpox (Variola)? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths should be conducted. During the outbreak, cases and deaths should be counted and reported. The age and sex distribution of cases should be analyzed, and risk factors should be assessed immediately."}, {"prompt": "How can temporal analysis help in understanding Smallpox (Variola) trends? related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly/monthly. Construct an epidemic curve to monitor the progress of the outbreak."}, {"prompt": "What are the benefits of temporal analysis in understanding Smallpox (Variola) trends? related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly/monthly. Construct an epidemic curve to monitor the progress of the outbreak."}, {"prompt": "How can data about place be analyzed and interpreted in the context of Smallpox (Variola)? related to Yellow Fever Disease", "completion": "Map the location of case households to identify potential clusters or areas of concern."}, {"prompt": "What methods are used for analyzing data about place in the context of Smallpox (Variola)? related to Yellow Fever Disease", "completion": "Map the location of case households to identify potential clusters or areas of concern."}, {"prompt": "What laboratory tests are used for diagnosing Smallpox (Variola)? related to Yellow Fever Disease", "completion": "Diagnostic tests for Smallpox (Variola) include the isolation of the variola virus from a clinical specimen or Polymerase chain reaction (PCR) assay identification of Variola DNA in a clinical specimen. These tests are only conducted in Level C or D laboratories. Specimens for testing include biopsy specimens, scabs, vesicular fluid, and blood samples. Specimens should be collected safely and stored appropriately before being transported to a reference laboratory. Diagnostic services for smallpox are not routinely available, and advance arrangements are usually required. The appropriate National authority or WHO should be contacted before shipping potential smallpox patient clinical specimens."}, {"prompt": "What are the diagnostic procedures for Smallpox (Variola)? related to Yellow Fever Disease", "completion": "Diagnostic tests for Smallpox (Variola) include the isolation of the variola virus from a clinical specimen or Polymerase chain reaction (PCR) assay identification of Variola DNA in a clinical specimen. These tests are only conducted in Level C or D laboratories. Specimens for testing include biopsy specimens, scabs, vesicular fluid, and blood samples. Specimens should be collected safely and stored appropriately before being transported to a reference laboratory. Diagnostic services for smallpox are not routinely available, and advance arrangements are usually required. The appropriate National authority or WHO should be contacted before shipping potential smallpox patient clinical specimens."}, {"prompt": "What references can be consulted for information about Smallpox (Variola)? related to Yellow Fever Disease", "completion": "1. WHO Fact Sheet, Smallpox. http://www.who.int/mediacentre/factsheets/smallpox"}, {"prompt": "Where can I find more details about Smallpox (Variola)? related to Yellow Fever Disease", "completion": "1. WHO Fact Sheet, Smallpox. http://www.who.int/mediacentre/factsheets/smallpox"}, {"prompt": "Explain Severe Pneumonia in Children under 5 years of age. related to Yellow Fever Disease", "completion": "The main bacterial causes of pneumonia among children are Streptococcus pneumoniae (the pneumococcus) and Haemophilus influenzae type b (Hib). The incubation period is usually less than 7 days, depending on the aetiology."}, {"prompt": "Describe Severe Pneumonia in Children under 5 years of age. related to Yellow Fever Disease", "completion": "The main bacterial causes of pneumonia among children are Streptococcus pneumoniae (the pneumococcus) and Haemophilus influenzae type b (Hib). The incubation period is usually less than 7 days, depending on the aetiology."}, {"prompt": "Elaborate on Severe Pneumonia in Children under 5 years of age. related to Yellow Fever Disease", "completion": "The main bacterial causes of pneumonia among children are Streptococcus pneumoniae (the pneumococcus) and Haemophilus influenzae type b (Hib). The incubation period is usually less than 7 days, depending on the aetiology."}, {"prompt": "Define Severe Pneumonia in Children under 5 years of age. related to Yellow Fever Disease", "completion": "The main bacterial causes of pneumonia among children are Streptococcus pneumoniae (the pneumococcus) and Haemophilus influenzae type b (Hib). The incubation period is usually less than 7 days, depending on the aetiology."}, {"prompt": "What is Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "The main bacterial causes of pneumonia among children are Streptococcus pneumoniae (the pneumococcus) and Haemophilus influenzae type b (Hib). The incubation period is usually less than 7 days, depending on the aetiology."}, {"prompt": "How is Severe Pneumonia in Children under 5 years of age transmitted? related to Yellow Fever Disease", "completion": "It is an infection of the lower airways caused by bacteria or viruses, transmitted person-to-person via aerosolized respiratory droplet spread."}, {"prompt": "What is the mode of transmission for Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "It is an infection of the lower airways caused by bacteria or viruses, transmitted person-to-person via aerosolized respiratory droplet spread."}, {"prompt": "How can Severe Pneumonia in Children under 5 years of age be transmitted? related to Yellow Fever Disease", "completion": "It is an infection of the lower airways caused by bacteria or viruses, transmitted person-to-person via aerosolized respiratory droplet spread."}, {"prompt": "Why is Severe Pneumonia in Children under 5 years of age considered a priority? related to Yellow Fever Disease", "completion": "Acute respiratory infections (ARIs) and pneumonia represent the number one cause of mortality among children less than 5 years of age."}, {"prompt": "What makes Severe Pneumonia in Children under 5 years of age a priority in public health? related to Yellow Fever Disease", "completion": "Acute respiratory infections (ARIs) and pneumonia represent the number one cause of mortality among children less than 5 years of age."}, {"prompt": "What are the reasons behind considering Severe Pneumonia in Children under 5 years of age a priority? related to Yellow Fever Disease", "completion": "Acute respiratory infections (ARIs) and pneumonia represent the number one cause of mortality among children less than 5 years of age."}, {"prompt": "Is there any additional information on Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "WHO and UNICEF recommend the use of the Integrated Management of Childhood Illness (IMCI) strategy to reduce morbidity and mortality attributable to childhood pneumonia. Early antimicrobial therapy has been shown to reduce mortality. Resistance of the pneumococcus and Hib to beta-lactams, sulfonamides, and other antimicrobials is increasing. Viruses such as respiratory syncytial virus (RSV) may also cause ARI and pneumonia."}, {"prompt": "Tell me more about Severe Pneumonia in Children under 5 years of age. related to Yellow Fever Disease", "completion": "WHO and UNICEF recommend the use of the Integrated Management of Childhood Illness (IMCI) strategy to reduce morbidity and mortality attributable to childhood pneumonia. Early antimicrobial therapy has been shown to reduce mortality. Resistance of the pneumococcus and Hib to beta-lactams, sulfonamides, and other antimicrobials is increasing. Viruses such as respiratory syncytial virus (RSV) may also cause ARI and pneumonia."}, {"prompt": "What are the surveillance goals for Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "The goals are the early identification of pneumonia cases and epidemics using clinical definitions, routine monitoring of antimicrobial resistance, and reducing the proportion of severe pneumonia cases compared to non-severe pneumonia cases to monitor the quality of interventions."}, {"prompt": "What are the objectives of surveillance for Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "The goals are the early identification of pneumonia cases and epidemics using clinical definitions, routine monitoring of antimicrobial resistance, and reducing the proportion of severe pneumonia cases compared to non-severe pneumonia cases to monitor the quality of interventions."}, {"prompt": "What is the standard case definition for Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "Suspected Case: A child presenting with cough or difficult breathing and having specific breath rates based on their age. Probable Case: A child presenting with cough or difficult breathing and any general danger sign, chest indrawing, or stridor in a calm child. Confirmed Case: Radiographic or laboratory confirmation of pneumonia, though it will not be feasible in most districts."}, {"prompt": "How is Severe Pneumonia in Children under 5 years of age diagnosed? related to Yellow Fever Disease", "completion": "Suspected Case: A child presenting with cough or difficult breathing and having specific breath rates based on their age. Probable Case: A child presenting with cough or difficult breathing and any general danger sign, chest indrawing, or stridor in a calm child. Confirmed Case: Radiographic or laboratory confirmation of pneumonia, though it will not be feasible in most districts."}, {"prompt": "What is the case definition for diagnosing Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "Suspected Case: A child presenting with cough or difficult breathing and having specific breath rates based on their age. Probable Case: A child presenting with cough or difficult breathing and any general danger sign, chest indrawing, or stridor in a calm child. Confirmed Case: Radiographic or laboratory confirmation of pneumonia, though it will not be feasible in most districts."}, {"prompt": "How should an alert be raised for Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "If there is an observation that the number of cases or deaths is increasing over a period of time, report the problem to the next level. Investigate the cause for the increase, ensure cases are managed according to IMCI guidelines, and treat cases appropriately with recommended antimicrobial drugs."}, {"prompt": "Under what circumstances should an alert be raised for Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "If there is an observation that the number of cases or deaths is increasing over a period of time, report the problem to the next level. Investigate the cause for the increase, ensure cases are managed according to IMCI guidelines, and treat cases appropriately with recommended antimicrobial drugs."}, {"prompt": "When should an alert be raised for Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "If there is an observation that the number of cases or deaths is increasing over a period of time, report the problem to the next level. Investigate the cause for the increase, ensure cases are managed according to IMCI guidelines, and treat cases appropriately with recommended antimicrobial drugs."}, {"prompt": "What actions should be taken if a case of Severe Pneumonia in Children under 5 years of age is detected? related to Yellow Fever Disease", "completion": "If the number of cases or deaths increases to twice the usual number during a similar period in the past, assess health worker practices of IMCI guidelines for assessing, classifying, and treating children with pneumonia and severe pneumonia. Identify high-risk populations and conduct community education about when to seek care for pneumonia."}, {"prompt": "What steps should be taken in response to a detected case of Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "If the number of cases or deaths increases to twice the usual number during a similar period in the past, assess health worker practices of IMCI guidelines for assessing, classifying, and treating children with pneumonia and severe pneumonia. Identify high-risk populations and conduct community education about when to seek care for pneumonia."}, {"prompt": "How should data about individuals with Severe Pneumonia in Children under 5 years of age be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count monthly pneumonia and severe pneumonia cases. Count pneumonia deaths. Analyze age distribution."}, {"prompt": "What are the methods used to analyze data about individuals with Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "Count monthly pneumonia and severe pneumonia cases. Count pneumonia deaths. Analyze age distribution."}, {"prompt": "How can we interpret the data on Severe Pneumonia in Children under 5 years of age cases and individuals? related to Yellow Fever Disease", "completion": "Count monthly pneumonia and severe pneumonia cases. Count pneumonia deaths. Analyze age distribution."}, {"prompt": "How should data about time in the context of Severe Pneumonia in Children under 5 years of age be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Conduct month-to-month analysis for unexpected or unusual increases. Graph cases and deaths by month. Construct an epidemic curve for outbreak cases. Plot month-to-month data and compare to previous periods."}, {"prompt": "What are the techniques used for temporal analysis of Severe Pneumonia in Children under 5 years of age cases? related to Yellow Fever Disease", "completion": "Conduct month-to-month analysis for unexpected or unusual increases. Graph cases and deaths by month. Construct an epidemic curve for outbreak cases. Plot month-to-month data and compare to previous periods."}, {"prompt": "How can temporal analysis help in understanding Severe Pneumonia in Children under 5 years of age trends? related to Yellow Fever Disease", "completion": "Conduct month-to-month analysis for unexpected or unusual increases. Graph cases and deaths by month. Construct an epidemic curve for outbreak cases. Plot month-to-month data and compare to previous periods."}, {"prompt": "How should data about place in the context of Severe Pneumonia in Children under 5 years of age be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "What are the methods used for spatial analysis of Severe Pneumonia in Children under 5 years of age cases? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "How can spatial analysis contribute to understanding Severe Pneumonia in Children under 5 years of age transmission? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "What are the laboratory procedures for diagnosing Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "How is Severe Pneumonia in Children under 5 years of age diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "What are the references for Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "1. Integrated Management of Childhood Illnesses. World Health Organization. WHO/CDR/95.14.1"}, {"prompt": "Where can I find more information about Severe Pneumonia in Children under 5 years of age? related to Yellow Fever Disease", "completion": "1. Integrated Management of Childhood Illnesses. World Health Organization. WHO/CDR/95.14.1"}, {"prompt": "Explain Severe Acute Respiratory Syndrome (SARS). related to Yellow Fever Disease", "completion": "Severe acute respiratory syndrome (SARS) was first recognized as a global threat in 2003 when international spread resulted in 8,098 SARS cases in 26 countries, with 774 deaths. The mean incubation period is 5 days, with the range of 2-10 days. Patients initially develop influenza-like prodromal symptoms including fever, malaise, myalgia, headache and rigors. Cough (initially dry), dyspnoea and diarrhoea may be present in the first week but more commonly reported in the second week of illness. Severe cases develop rapidly progressing respiratory distress. Up to 70% of the patients develop diarrhoea."}, {"prompt": "Describe Severe Acute Respiratory Syndrome (SARS). related to Yellow Fever Disease", "completion": "Severe acute respiratory syndrome (SARS) was first recognized as a global threat in 2003 when international spread resulted in 8,098 SARS cases in 26 countries, with 774 deaths. The mean incubation period is 5 days, with the range of 2-10 days. Patients initially develop influenza-like prodromal symptoms including fever, malaise, myalgia, headache and rigors. Cough (initially dry), dyspnoea and diarrhoea may be present in the first week but more commonly reported in the second week of illness. Severe cases develop rapidly progressing respiratory distress. Up to 70% of the patients develop diarrhoea."}, {"prompt": "Elaborate on Severe Acute Respiratory Syndrome (SARS). related to Yellow Fever Disease", "completion": "Severe acute respiratory syndrome (SARS) was first recognized as a global threat in 2003 when international spread resulted in 8,098 SARS cases in 26 countries, with 774 deaths. The mean incubation period is 5 days, with the range of 2-10 days. Patients initially develop influenza-like prodromal symptoms including fever, malaise, myalgia, headache and rigors. Cough (initially dry), dyspnoea and diarrhoea may be present in the first week but more commonly reported in the second week of illness. Severe cases develop rapidly progressing respiratory distress. Up to 70% of the patients develop diarrhoea."}, {"prompt": "Define Severe Acute Respiratory Syndrome (SARS). related to Yellow Fever Disease", "completion": "Severe acute respiratory syndrome (SARS) was first recognized as a global threat in 2003 when international spread resulted in 8,098 SARS cases in 26 countries, with 774 deaths. The mean incubation period is 5 days, with the range of 2-10 days. Patients initially develop influenza-like prodromal symptoms including fever, malaise, myalgia, headache and rigors. Cough (initially dry), dyspnoea and diarrhoea may be present in the first week but more commonly reported in the second week of illness. Severe cases develop rapidly progressing respiratory distress. Up to 70% of the patients develop diarrhoea."}, {"prompt": "What is the nature of Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Severe acute respiratory syndrome (SARS) was first recognized as a global threat in 2003 when international spread resulted in 8,098 SARS cases in 26 countries, with 774 deaths. The mean incubation period is 5 days, with the range of 2-10 days. Patients initially develop influenza-like prodromal symptoms including fever, malaise, myalgia, headache and rigors. Cough (initially dry), dyspnoea and diarrhoea may be present in the first week but more commonly reported in the second week of illness. Severe cases develop rapidly progressing respiratory distress. Up to 70% of the patients develop diarrhoea."}, {"prompt": "How is Severe Acute Respiratory Syndrome (SARS) transmitted? related to Yellow Fever Disease", "completion": "Nosocomial transmission of SARS-CoV was a striking feature of the SARS outbreak."}, {"prompt": "What are the methods of transmission for Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Nosocomial transmission of SARS-CoV was a striking feature of the SARS outbreak."}, {"prompt": "Explain the modes of transmission for Severe Acute Respiratory Syndrome (SARS). related to Yellow Fever Disease", "completion": "Nosocomial transmission of SARS-CoV was a striking feature of the SARS outbreak."}, {"prompt": "Why is Severe Acute Respiratory Syndrome (SARS) a global health priority? related to Yellow Fever Disease", "completion": "In the inter-epidemic period, all countries must remain vigilant for the recurrence of SARS and maintain their ability to detect and respond to the possible re-emergence of SARS."}, {"prompt": "What makes Severe Acute Respiratory Syndrome (SARS) a priority in global health efforts? related to Yellow Fever Disease", "completion": "In the inter-epidemic period, all countries must remain vigilant for the recurrence of SARS and maintain their ability to detect and respond to the possible re-emergence of SARS."}, {"prompt": "What are the reasons behind Severe Acute Respiratory Syndrome (SARS) being a global health priority? related to Yellow Fever Disease", "completion": "In the inter-epidemic period, all countries must remain vigilant for the recurrence of SARS and maintain their ability to detect and respond to the possible re-emergence of SARS."}, {"prompt": "Is there any additional information on Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Disease transmission occurs mainly during the second week of illness. The SARS coronavirus (SARS-CoV) which causes SARS is believed to be an animal virus that crossed the species barrier to humans recently. Immediate Notification to WHO is formally required by IHR."}, {"prompt": "Are there any other important details about Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Disease transmission occurs mainly during the second week of illness. The SARS coronavirus (SARS-CoV) which causes SARS is believed to be an animal virus that crossed the species barrier to humans recently. Immediate Notification to WHO is formally required by IHR."}, {"prompt": "What else should I know about Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Disease transmission occurs mainly during the second week of illness. The SARS coronavirus (SARS-CoV) which causes SARS is believed to be an animal virus that crossed the species barrier to humans recently. Immediate Notification to WHO is formally required by IHR."}, {"prompt": "What are the goals of surveillance for Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "The goals are for the early detection and investigation of individuals with clinically apparent SARS-CoV."}, {"prompt": "What is the aim of surveillance for Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "The goals are for the early detection and investigation of individuals with clinically apparent SARS-CoV."}, {"prompt": "What are the main objectives of surveillance for Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "The goals are for the early detection and investigation of individuals with clinically apparent SARS-CoV."}, {"prompt": "Define the standard case definition for Severe Acute Respiratory Syndrome (SARS). related to Yellow Fever Disease", "completion": "Suspected Case: A history of fever, or documented fever 2 38 \u00b0C AND One or more symptoms of lower respiratory tract illness (cough, difficulty breathing, shortness of breath) AND Radiographic evidence of lung infiltrates consistent with pneumonia or ARDS or autopsy findings consistent with the pathology of pneumonia or ARDS without an identifiable cause AND No alternative diagnosis can fully explain the illness. Confirmed Case: An individual who tests positive for SARS-CoV infection by the WHO recommended testing procedures."}, {"prompt": "What is the formal case definition for Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Suspected Case: A history of fever, or documented fever 2 38 \u00b0C AND One or more symptoms of lower respiratory tract illness (cough, difficulty breathing, shortness of breath) AND Radiographic evidence of lung infiltrates consistent with pneumonia or ARDS or autopsy findings consistent with the pathology of pneumonia or ARDS without an identifiable cause AND No alternative diagnosis can fully explain the illness. Confirmed Case: An individual who tests positive for SARS-CoV infection by the WHO recommended testing procedures."}, {"prompt": "What are the criteria used to define a suspected case of Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Suspected Case: A history of fever, or documented fever 2 38 \u00b0C AND One or more symptoms of lower respiratory tract illness (cough, difficulty breathing, shortness of breath) AND Radiographic evidence of lung infiltrates consistent with pneumonia or ARDS or autopsy findings consistent with the pathology of pneumonia or ARDS without an identifiable cause AND No alternative diagnosis can fully explain the illness. Confirmed Case: An individual who tests positive for SARS-CoV infection by the WHO recommended testing procedures."}, {"prompt": "When should an alert be raised for Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Report case-based information immediately to the appropriate levels. Practice infection control precautions for an acute respiratory disease with epidemic/pandemic potential immediately and enhance Standard Precautions throughout the health care setting. Treat and manage the patient according to national guidelines. Collect and transport laboratory specimens from case-patient and from symptomatic contacts and arrange for laboratory testing. Review clinical history and exposure history during 2-10 days before disease onset. Identify and follow-up close contacts of case-patient. Conduct active searches for additional cases. Expedite the diagnosis.(WHO will assist in the investigation of SARS alerts as appropriate, including facilitating access to laboratory services)"}, {"prompt": "Under what circumstances should an alert be raised for Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Report case-based information immediately to the appropriate levels. Practice infection control precautions for an acute respiratory disease with epidemic/pandemic potential immediately and enhance Standard Precautions throughout the health care setting. Treat and manage the patient according to national guidelines. Collect and transport laboratory specimens from case-patient and from symptomatic contacts and arrange for laboratory testing. Review clinical history and exposure history during 2-10 days before disease onset. Identify and follow-up close contacts of case-patient. Conduct active searches for additional cases. Expedite the diagnosis.(WHO will assist in the investigation of SARS alerts as appropriate, including facilitating access to laboratory services)"}, {"prompt": "What actions should be taken if a case of Severe Acute Respiratory Syndrome (SARS) is detected? related to Yellow Fever Disease", "completion": "1) An individual with clinical evidence of SARS AND with an epidemiological risk factor for SARS-CoV infection in the 10 days before the onset of symptoms OR Two or more health-care workers with clinical evidence of SARS in the same health- care unit and with onset of illness in the same 10-day period OR Three or more persons (health-care workers and/or patients and/or visitors) with clinical evidence of SARS with onset of illness in the same 10-day period and epidemiologically linked to a health-care facility."}, {"prompt": "What steps should be taken if a case of Severe Acute Respiratory Syndrome (SARS) is identified? related to Yellow Fever Disease", "completion": "1) An individual with clinical evidence of SARS AND with an epidemiological risk factor for SARS-CoV infection in the 10 days before the onset of symptoms OR Two or more health-care workers with clinical evidence of SARS in the same health- care unit and with onset of illness in the same 10-day period OR Three or more persons (health-care workers and/or patients and/or visitors) with clinical evidence of SARS with onset of illness in the same 10-day period and epidemiologically linked to a health-care facility."}, {"prompt": "How should data about individuals with Severe Acute Respiratory Syndrome (SARS) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths. During the outbreak, count and report cases and deaths. Analyze age and sex distribution. Assess risk factors immediately."}, {"prompt": "What are the methods used to analyze data about individuals with Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths. During the outbreak, count and report cases and deaths. Analyze age and sex distribution. Assess risk factors immediately."}, {"prompt": "How can we interpret the data on Severe Acute Respiratory Syndrome (SARS) cases and individuals? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths. During the outbreak, count and report cases and deaths. Analyze age and sex distribution. Assess risk factors immediately."}, {"prompt": "How should data about time in the context of Severe Acute Respiratory Syndrome (SARS) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly/monthly. Construct an epidemic curve during the outbreak."}, {"prompt": "What is the best way to analyze data about time in the context of Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly/monthly. Construct an epidemic curve during the outbreak."}, {"prompt": "How can we interpret the data on the timeline of Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly/monthly. Construct an epidemic curve during the outbreak."}, {"prompt": "How should data about place in the context of Severe Acute Respiratory Syndrome (SARS) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot locations of case households and work sites using precise mapping."}, {"prompt": "What is the appropriate method to analyze data about the locations of Severe Acute Respiratory Syndrome (SARS) cases? related to Yellow Fever Disease", "completion": "Plot locations of case households and work sites using precise mapping."}, {"prompt": "How can we interpret the data on the geographic distribution of Severe Acute Respiratory Syndrome (SARS) cases? related to Yellow Fever Disease", "completion": "Plot locations of case households and work sites using precise mapping."}, {"prompt": "How is Severe Acute Respiratory Syndrome (SARS) diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Confirmed positive PCR for SARS virus: At least 2 different clinical specimens (eg nasopharyngeal and stool) OR The same clinical specimen collected on 2 or more days during the course of the illness (eg 2 or more nasopharyngeal aspirates) OR 2 different assays or repeat PCR using the original clinical sample on each occasion of testing. Seronconversion by ELISA or IFA: Negative antibody test on acute serum followed by positive antibody test on convalescent serum OR Four-fold or greater rise in antibody titre between acute and convalescent phase sera tested in parallel. Virus isolation: Isolation in cell culture of SARS-Cov from any specimen; plus PCR confirmation using a validated method"}, {"prompt": "What are the laboratory procedures used to diagnose Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "Confirmed positive PCR for SARS virus: At least 2 different clinical specimens (eg nasopharyngeal and stool) OR The same clinical specimen collected on 2 or more days during the course of the illness (eg 2 or more nasopharyngeal aspirates) OR 2 different assays or repeat PCR using the original clinical sample on each occasion of testing. Seronconversion by ELISA or IFA: Negative antibody test on acute serum followed by positive antibody test on convalescent serum OR Four-fold or greater rise in antibody titre between acute and convalescent phase sera tested in parallel. Virus isolation: Isolation in cell culture of SARS-Cov from any specimen; plus PCR confirmation using a validated method"}, {"prompt": "How can Severe Acute Respiratory Syndrome (SARS) be diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Confirmed positive PCR for SARS virus: At least 2 different clinical specimens (eg nasopharyngeal and stool) OR The same clinical specimen collected on 2 or more days during the course of the illness (eg 2 or more nasopharyngeal aspirates) OR 2 different assays or repeat PCR using the original clinical sample on each occasion of testing. Seronconversion by ELISA or IFA: Negative antibody test on acute serum followed by positive antibody test on convalescent serum OR Four-fold or greater rise in antibody titre between acute and convalescent phase sera tested in parallel. Virus isolation: Isolation in cell culture of SARS-Cov from any specimen; plus PCR confirmation using a validated method"}, {"prompt": "What are the references for Severe Acute Respiratory Syndrome (SARS)? related to Yellow Fever Disease", "completion": "1. WHO Guidelines for the Global Surveillance of SARS, Updated Recommendations, October 2004.\n2. WHO Interim Guidelines, Infection Prevention and Control of Epidemic- and Pandemic- Prone Acute Respiratory Diseases in Health Care, June 2007. WHO/CDS/EPR/2007.6.\n3. Use of laboratory methods for SARS diagnosis, WHO.\n4. WHO Biosafety guidelines for handling of SARS specimens.\n5. A practical Guide for SARS laboratories: from samples collection to shipment. WHO, 29 Dec 2003."}, {"prompt": "Explain Severe Acute Respiratory Infections (SARIs). related to Yellow Fever Disease", "completion": "Severe acute respiratory infections (SARIs) are a significant cause of infectious disease morbidity and mortality in Africa."}, {"prompt": "Define Severe Acute Respiratory Infections (SARIs). related to Yellow Fever Disease", "completion": "Severe acute respiratory infections (SARIs) are a significant cause of infectious disease morbidity and mortality in Africa."}, {"prompt": "Elaborate on Severe Acute Respiratory Infections (SARIs). related to Yellow Fever Disease", "completion": "Severe acute respiratory infections (SARIs) are a significant cause of infectious disease morbidity and mortality in Africa."}, {"prompt": "What are Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Severe acute respiratory infections (SARIs) are a significant cause of infectious disease morbidity and mortality in Africa."}, {"prompt": "Describe Severe Acute Respiratory Infections (SARIs). related to Yellow Fever Disease", "completion": "Severe acute respiratory infections (SARIs) are a significant cause of infectious disease morbidity and mortality in Africa."}, {"prompt": "How do Severe Acute Respiratory Infections (SARIs) spread? related to Yellow Fever Disease", "completion": "Severe Acute Respiratory Infections (SARIs) are transmitted through respiratory droplets."}, {"prompt": "What is the mode of transmission for Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Severe Acute Respiratory Infections (SARIs) are transmitted through respiratory droplets."}, {"prompt": "Explain the transmission of Severe Acute Respiratory Infections (SARIs). related to Yellow Fever Disease", "completion": "Severe Acute Respiratory Infections (SARIs) are transmitted through respiratory droplets."}, {"prompt": "What are the reasons for considering Severe Acute Respiratory Infections (SARIs) a priority? related to Yellow Fever Disease", "completion": "An improved understanding of the epidemiology and seasonality of SARIs in Africa is essential for optimizing public health strategies for their prevention and control (e.g., vaccines and antivirals for prophylaxis and treatment, infection control)."}, {"prompt": "Why are Severe Acute Respiratory Infections (SARIs) given priority in public health efforts? related to Yellow Fever Disease", "completion": "An improved understanding of the epidemiology and seasonality of SARIs in Africa is essential for optimizing public health strategies for their prevention and control (e.g., vaccines and antivirals for prophylaxis and treatment, infection control)."}, {"prompt": "What makes Severe Acute Respiratory Infections (SARIs) a priority in public health? related to Yellow Fever Disease", "completion": "An improved understanding of the epidemiology and seasonality of SARIs in Africa is essential for optimizing public health strategies for their prevention and control (e.g., vaccines and antivirals for prophylaxis and treatment, infection control)."}, {"prompt": "Who is most vulnerable to Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The mortality rates of SARIs are particularly high among infants, children, and the elderly."}, {"prompt": "Which groups are at a higher risk of Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The mortality rates of SARIs are particularly high among infants, children, and the elderly."}, {"prompt": "Who are the individuals most susceptible to Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The mortality rates of SARIs are particularly high among infants, children, and the elderly."}, {"prompt": "Are there any additional details on Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The threat of SARIs due to novel organisms that have epidemic or pandemic potential warrants special precautions and preparedness. Respiratory disease events that may constitute a public health emergency of international concern include severe acute respiratory syndrome (SARS); human influenza caused by a new subtype, including human episodes of avian influenza; pneumonic plague; and novel agents that can cause large-scale SARI outbreaks with high morbidity and mortality."}, {"prompt": "What other information is relevant to Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The threat of SARIs due to novel organisms that have epidemic or pandemic potential warrants special precautions and preparedness. Respiratory disease events that may constitute a public health emergency of international concern include severe acute respiratory syndrome (SARS); human influenza caused by a new subtype, including human episodes of avian influenza; pneumonic plague; and novel agents that can cause large-scale SARI outbreaks with high morbidity and mortality."}, {"prompt": "Are there any additional details about Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The threat of SARIs due to novel organisms that have epidemic or pandemic potential warrants special precautions and preparedness. Respiratory disease events that may constitute a public health emergency of international concern include severe acute respiratory syndrome (SARS); human influenza caused by a new subtype, including human episodes of avian influenza; pneumonic plague; and novel agents that can cause large-scale SARI outbreaks with high morbidity and mortality."}, {"prompt": "What are the surveillance objectives for Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The goals are to detect, in a timely manner, unusually severe morbidity and mortality caused by both known and unknown respiratory pathogens that have the potential for large scale epidemics or pandemics. Additionally, it aims to characterize and monitor trends in illnesses and deaths attributable to SARIs."}, {"prompt": "What is the purpose of surveillance for Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The goals are to detect, in a timely manner, unusually severe morbidity and mortality caused by both known and unknown respiratory pathogens that have the potential for large scale epidemics or pandemics. Additionally, it aims to characterize and monitor trends in illnesses and deaths attributable to SARIs."}, {"prompt": "What are the targets of surveillance for Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "The goals are to detect, in a timely manner, unusually severe morbidity and mortality caused by both known and unknown respiratory pathogens that have the potential for large scale epidemics or pandemics. Additionally, it aims to characterize and monitor trends in illnesses and deaths attributable to SARIs."}, {"prompt": "What defines a suspected case of Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Any severely ill person presenting with manifestations of acute lower respiratory infection with: Sudden onset of fever (>38\u00b0C) AND Cough or sore throat AND Shortness of breath, or difficulty breathing with or without Clinical or radiographic findings of pneumonia OR Any person who died of an unexplained respiratory illness."}, {"prompt": "How is a suspected case of Severe Acute Respiratory Infections (SARIs) identified? related to Yellow Fever Disease", "completion": "Any severely ill person presenting with manifestations of acute lower respiratory infection with: Sudden onset of fever (>38\u00b0C) AND Cough or sore throat AND Shortness of breath, or difficulty breathing with or without Clinical or radiographic findings of pneumonia OR Any person who died of an unexplained respiratory illness."}, {"prompt": "What are the criteria for identifying a suspected case of Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Any severely ill person presenting with manifestations of acute lower respiratory infection with: Sudden onset of fever (>38\u00b0C) AND Cough or sore throat AND Shortness of breath, or difficulty breathing with or without Clinical or radiographic findings of pneumonia OR Any person who died of an unexplained respiratory illness."}, {"prompt": "How should an alert be raised if there's a suspected case of Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "An alert should be raised if a single case of an epidemic- or pandemic-prone acute respiratory disease is suspected. OR If there is an unusual event (deaths, outbreak) of severe acute respiratory infection: Atypical cases of influenza-like illness (ILI) or severe acute respiratory infection (SARI). Two or more persons presenting with a SARI or who died from a SARI are detected with onset of illness in a two-week period and in the same geographical area and/or are epidemiologically linked. Health-care workers with only occupational exposure risks develop SARI after providing care to patients with SARI. Persons who have contact with birds/animals present with SARI; Any rumor of clusters of severe acute respiratory infections or of atypical respiratory infections."}, {"prompt": "When should an alert be raised for suspected Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "An alert should be raised if a single case of an epidemic- or pandemic-prone acute respiratory disease is suspected. OR If there is an unusual event (deaths, outbreak) of severe acute respiratory infection: Atypical cases of influenza-like illness (ILI) or severe acute respiratory infection (SARI). Two or more persons presenting with a SARI or who died from a SARI are detected with onset of illness in a two-week period and in the same geographical area and/or are epidemiologically linked. Health-care workers with only occupational exposure risks develop SARI after providing care to patients with SARI. Persons who have contact with birds/animals present with SARI; Any rumor of clusters of severe acute respiratory infections or of atypical respiratory infections."}, {"prompt": "What actions should be taken upon detecting a case of Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Respond to a suspected case of an epidemic- or pandemic-prone acute respiratory disease or to an usual event of severe acute respiratory infections: Report case-based information immediately to the appropriate levels. Practice infection control precautions for an acute respiratory disease with epidemic/pandemic potential immediately and enhance Standard Precautions throughout the health care setting. Treat and manage the patient according to national guidelines. Collect and transport laboratory specimens from case-patient and from symptomatic contacts and arrange for laboratory testing. Review clinical history and exposure history during 7 days before disease onset. Identify and follow-up close contacts of case-patient. Conduct active searches for additional cases."}, {"prompt": "What steps should be taken if a person is detected with Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Respond to a suspected case of an epidemic- or pandemic-prone acute respiratory disease or to an usual event of severe acute respiratory infections: Report case-based information immediately to the appropriate levels. Practice infection control precautions for an acute respiratory disease with epidemic/pandemic potential immediately and enhance Standard Precautions throughout the health care setting. Treat and manage the patient according to national guidelines. Collect and transport laboratory specimens from case-patient and from symptomatic contacts and arrange for laboratory testing. Review clinical history and exposure history during 7 days before disease onset. Identify and follow-up close contacts of case-patient. Conduct active searches for additional cases."}, {"prompt": "How should data about individuals with Severe Acute Respiratory Infections (SARIs) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Characterize the illness in terms of clinical presentation, the spectrum of disease, the proportion of cases requiring hospitalization, clinical outcomes, case fatality ratio, attack rates by age/occupation/blood relation."}, {"prompt": "What are the methods used to analyze data about individuals with Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Characterize the illness in terms of clinical presentation, the spectrum of disease, the proportion of cases requiring hospitalization, clinical outcomes, case fatality ratio, attack rates by age/occupation/blood relation."}, {"prompt": "How can we interpret the data on individuals with Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Characterize the illness in terms of clinical presentation, the spectrum of disease, the proportion of cases requiring hospitalization, clinical outcomes, case fatality ratio, attack rates by age/occupation/blood relation."}, {"prompt": "How should data about time in the context of Severe Acute Respiratory Infections (SARIs) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Estimate incubation period; describe transmission patterns."}, {"prompt": "What are the techniques used for temporal analysis of Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Estimate incubation period; describe transmission patterns."}, {"prompt": "How can temporal analysis help in understanding Severe Acute Respiratory Infections (SARIs) trends? related to Yellow Fever Disease", "completion": "Estimate incubation period; describe transmission patterns."}, {"prompt": "How should data about place in the context of Severe Acute Respiratory Infections (SARIs) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Describe risk factors, possible exposures. Ascertain whether any evidence exists that the virus may have increased its ability to cause human disease or improved its transmissibility."}, {"prompt": "What are the methods used for spatial analysis of Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Describe risk factors, possible exposures. Ascertain whether any evidence exists that the virus may have increased its ability to cause human disease or improved its transmissibility."}, {"prompt": "How can spatial analysis of Severe Acute Respiratory Infections (SARIs) provide insights? related to Yellow Fever Disease", "completion": "Describe risk factors, possible exposures. Ascertain whether any evidence exists that the virus may have increased its ability to cause human disease or improved its transmissibility."}, {"prompt": "How is Severe Acute Respiratory Infections (SARIs) diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "What are the laboratory procedures for diagnosing Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "How are Severe Acute Respiratory Infections (SARIs) diagnosed in healthcare settings? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "What are the references for Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "1. International Health Regulations, IHR (2005).\n2. AFRO Technical Guidelines for Integrated Disease Surveillance in the African Region, May 2002.\n3. WHO guidelines for investigation of human cases of avian influenza A(H5N1), January 2007.\n4. WHO interim guidelines on infection prevention and control of epidemic- and pandemic- prone acute respiratory diseases in health care, June 2007.\n5. WHO guidelines for the collection of human specimens for laboratory diagnosis of avian influenza infection, 12 January 2005.\n6. Collecting, preserving and shipping specimens for the diagnosis of avian influenza A(H5N1) virus infection. Guide for field operations, October 2006."}, {"prompt": "What are the official documents for Severe Acute Respiratory Infections (SARIs)? related to Yellow Fever Disease", "completion": "1. International Health Regulations, IHR (2005).\n2. AFRO Technical Guidelines for Integrated Disease Surveillance in the African Region, May 2002.\n3. WHO guidelines for investigation of human cases of avian influenza A(H5N1), January 2007.\n4. WHO interim guidelines on infection prevention and control of epidemic- and pandemic- prone acute respiratory diseases in health care, June 2007.\n5. WHO guidelines for the collection of human specimens for laboratory diagnosis of avian influenza infection, 12 January 2005.\n6. Collecting, preserving and shipping specimens for the diagnosis of avian influenza A(H5N1) virus infection. Guide for field operations, October 2006."}, {"prompt": "Explain Rift Valley Fever (RVF). related to Yellow Fever Disease", "completion": "Rift Valley Fever (RVF) is a viral disease that affects mainly animals and occasionally humans. The virus is a member of the Phlebovirus genus, one of the five genera in the family Bunyaviridae. The incubation period of RVF varies from 2 to 6 days. The clinical symptoms include an influenza-like illness, with sudden onset of fever, headache, myalgia and backache. These symptoms usually last from 4 to 7 days. Most of the infected people recover on their own. However, a small proportion (about 1%) get complications such as vomiting blood, nose bleeding and passing bloody stool. Other severe types of the disease are eye disease and meningo-encephalitis."}, {"prompt": "Describe Rift Valley Fever (RVF). related to Yellow Fever Disease", "completion": "Rift Valley Fever (RVF) is a viral disease that affects mainly animals and occasionally humans. The virus is a member of the Phlebovirus genus, one of the five genera in the family Bunyaviridae. The incubation period of RVF varies from 2 to 6 days. The clinical symptoms include an influenza-like illness, with sudden onset of fever, headache, myalgia and backache. These symptoms usually last from 4 to 7 days. Most of the infected people recover on their own. However, a small proportion (about 1%) get complications such as vomiting blood, nose bleeding and passing bloody stool. Other severe types of the disease are eye disease and meningo-encephalitis."}, {"prompt": "Elaborate on Rift Valley Fever (RVF). related to Yellow Fever Disease", "completion": "Rift Valley Fever (RVF) is a viral disease that affects mainly animals and occasionally humans. The virus is a member of the Phlebovirus genus, one of the five genera in the family Bunyaviridae. The incubation period of RVF varies from 2 to 6 days. The clinical symptoms include an influenza-like illness, with sudden onset of fever, headache, myalgia and backache. These symptoms usually last from 4 to 7 days. Most of the infected people recover on their own. However, a small proportion (about 1%) get complications such as vomiting blood, nose bleeding and passing bloody stool. Other severe types of the disease are eye disease and meningo-encephalitis."}, {"prompt": "Define Rift Valley Fever (RVF). related to Yellow Fever Disease", "completion": "Rift Valley Fever (RVF) is a viral disease that affects mainly animals and occasionally humans. The virus is a member of the Phlebovirus genus, one of the five genera in the family Bunyaviridae. The incubation period of RVF varies from 2 to 6 days. The clinical symptoms include an influenza-like illness, with sudden onset of fever, headache, myalgia and backache. These symptoms usually last from 4 to 7 days. Most of the infected people recover on their own. However, a small proportion (about 1%) get complications such as vomiting blood, nose bleeding and passing bloody stool. Other severe types of the disease are eye disease and meningo-encephalitis."}, {"prompt": "What is the nature of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Rift Valley Fever (RVF) is a viral disease that affects mainly animals and occasionally humans. The virus is a member of the Phlebovirus genus, one of the five genera in the family Bunyaviridae. The incubation period of RVF varies from 2 to 6 days. The clinical symptoms include an influenza-like illness, with sudden onset of fever, headache, myalgia and backache. These symptoms usually last from 4 to 7 days. Most of the infected people recover on their own. However, a small proportion (about 1%) get complications such as vomiting blood, nose bleeding and passing bloody stool. Other severe types of the disease are eye disease and meningo-encephalitis."}, {"prompt": "How is Rift Valley Fever (RVF) transmitted? related to Yellow Fever Disease", "completion": "RVF is mainly transmitted from animals (sheep, cattle, goats, camels) to humans through close contact with infected animals (such as handling meat and body fluids and consumption of raw milk). During established RVF outbreaks in animals humans can also get infected through bites of infected mosquitoes and other biting insects."}, {"prompt": "What are the modes of transmission for Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "RVF is mainly transmitted from animals (sheep, cattle, goats, camels) to humans through close contact with infected animals (such as handling meat and body fluids and consumption of raw milk). During established RVF outbreaks in animals humans can also get infected through bites of infected mosquitoes and other biting insects."}, {"prompt": "Explain the transmission of Rift Valley Fever (RVF). related to Yellow Fever Disease", "completion": "RVF is mainly transmitted from animals (sheep, cattle, goats, camels) to humans through close contact with infected animals (such as handling meat and body fluids and consumption of raw milk). During established RVF outbreaks in animals humans can also get infected through bites of infected mosquitoes and other biting insects."}, {"prompt": "How does Rift Valley Fever (RVF) spread? related to Yellow Fever Disease", "completion": "RVF is mainly transmitted from animals (sheep, cattle, goats, camels) to humans through close contact with infected animals (such as handling meat and body fluids and consumption of raw milk). During established RVF outbreaks in animals humans can also get infected through bites of infected mosquitoes and other biting insects."}, {"prompt": "Why is Rift Valley Fever (RVF) considered a priority? related to Yellow Fever Disease", "completion": "Management of RVF in humans is mainly supportive as there is no definitive treatment for RVF. Early detection and management of the disease is important. Human control of RVF is through control of the disease in animals through a sustained vaccination program and limiting human-animal contact. Use of insecticide-treated nets and mosquito repellants can also reduce infections in humans. In addition to human suffering and death, RVF has far-reaching economic implications to the Livestock industry. In outbreak settings, the disease manifestation includes non-hemorrhagic febrile syndromes, and laboratory testing should be considered among persons with milder symptoms suggestive of viral illness."}, {"prompt": "What makes Rift Valley Fever (RVF) a priority disease? related to Yellow Fever Disease", "completion": "Management of RVF in humans is mainly supportive as there is no definitive treatment for RVF. Early detection and management of the disease is important. Human control of RVF is through control of the disease in animals through a sustained vaccination program and limiting human-animal contact. Use of insecticide-treated nets and mosquito repellants can also reduce infections in humans. In addition to human suffering and death, RVF has far-reaching economic implications to the Livestock industry. In outbreak settings, the disease manifestation includes non-hemorrhagic febrile syndromes, and laboratory testing should be considered among persons with milder symptoms suggestive of viral illness."}, {"prompt": "Why is Rift Valley Fever (RVF) of significant concern? related to Yellow Fever Disease", "completion": "Management of RVF in humans is mainly supportive as there is no definitive treatment for RVF. Early detection and management of the disease is important. Human control of RVF is through control of the disease in animals through a sustained vaccination program and limiting human-animal contact. Use of insecticide-treated nets and mosquito repellants can also reduce infections in humans. In addition to human suffering and death, RVF has far-reaching economic implications to the Livestock industry. In outbreak settings, the disease manifestation includes non-hemorrhagic febrile syndromes, and laboratory testing should be considered among persons with milder symptoms suggestive of viral illness."}, {"prompt": "Why is Rift Valley Fever (RVF) a significant public health concern? related to Yellow Fever Disease", "completion": "Management of RVF in humans is mainly supportive as there is no definitive treatment for RVF. Early detection and management of the disease is important. Human control of RVF is through control of the disease in animals through a sustained vaccination program and limiting human-animal contact. Use of insecticide-treated nets and mosquito repellants can also reduce infections in humans. In addition to human suffering and death, RVF has far-reaching economic implications to the Livestock industry. In outbreak settings, the disease manifestation includes non-hemorrhagic febrile syndromes, and laboratory testing should be considered among persons with milder symptoms suggestive of viral illness."}, {"prompt": "Is there any additional information on Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "The disease is frequently reported following heavy rainfall and floods. It was first isolated in Rift Valley Province of Kenya in 1930. The disease was reported in Kenya after the El Nino flooding of 1997/98 and more recently in 2006 to 2007. In 2007 and 2010, Tanzania and South Africa respectively were also affected. Other outbreaks have previously been reported in Somalia, Egypt, Saudi Arabia and Yemen."}, {"prompt": "What additional details are there about Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "The disease is frequently reported following heavy rainfall and floods. It was first isolated in Rift Valley Province of Kenya in 1930. The disease was reported in Kenya after the El Nino flooding of 1997/98 and more recently in 2006 to 2007. In 2007 and 2010, Tanzania and South Africa respectively were also affected. Other outbreaks have previously been reported in Somalia, Egypt, Saudi Arabia and Yemen."}, {"prompt": "Tell me more about Rift Valley Fever (RVF). related to Yellow Fever Disease", "completion": "The disease is frequently reported following heavy rainfall and floods. It was first isolated in Rift Valley Province of Kenya in 1930. The disease was reported in Kenya after the El Nino flooding of 1997/98 and more recently in 2006 to 2007. In 2007 and 2010, Tanzania and South Africa respectively were also affected. Other outbreaks have previously been reported in Somalia, Egypt, Saudi Arabia and Yemen."}, {"prompt": "What are the key features of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "The disease is frequently reported following heavy rainfall and floods. It was first isolated in Rift Valley Province of Kenya in 1930. The disease was reported in Kenya after the El Nino flooding of 1997/98 and more recently in 2006 to 2007. In 2007 and 2010, Tanzania and South Africa respectively were also affected. Other outbreaks have previously been reported in Somalia, Egypt, Saudi Arabia and Yemen."}, {"prompt": "What are the surveillance goals for Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Detect, confirm aetiology and respond to outbreaks promptly of all cases of suspected VHF."}, {"prompt": "What are the objectives of Rift Valley Fever (RVF) surveillance? related to Yellow Fever Disease", "completion": "Detect, confirm aetiology and respond to outbreaks promptly of all cases of suspected VHF."}, {"prompt": "What is the primary focus of Rift Valley Fever (RVF) surveillance? related to Yellow Fever Disease", "completion": "Detect, confirm aetiology and respond to outbreaks promptly of all cases of suspected VHF."}, {"prompt": "What is the standard case definition for a suspected case of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Early disease: Acute febrile illness (axillary temperature >37.5 \u00b0C or oral temperature of >38.0\u00b0C) of more than 48 hours duration that does not respond to antibiotic or antimalarial therapy, and is associated with: Direct contact with sick or dead animal or its products AND / OR: Recent travel (during last week) to, or living in an area where, after heavy rains, livestock die or abort, and where RVF virus activity is suspected/confirmed AND / OR: Abrupt onset of any 1 or more of the following: exhaustion, backache, muscle pains, headache (often severe), discomfort when exposed to light, and nausea/vomiting AND / OR: Nausea/vomiting, diarrhoea OR abdominal pain with 1 or more of the following: Severe pallor (or Hb < 8 gm/dL), Low platelets (thrombocytopenia) as evidence by presence of small skin and mucous membrane haemorrhages (petechiae) (or platelet count < 100x109 / dL), Evidence of kidney failure (edema, reduced urine output) (or creatinine > 150 mol/L) AND / OR: Evidence of bleeding into skin, bleeding from puncture wounds, from mucous membranes or nose, from gastrointestinal tract and unnatural bleeding from vagina AND / OR: Clinical jaundice (3-fold increase above normal of transaminases). Late stages of diseases or complications (2-3 weeks after onset Patients who have experienced, in the preceding month a flu-like illness, with clinical criteria, who additionally develop the following: CNS manifestations which resemble meningo-encephalitis AND/OR: Unexplained visual loss OR: Unexplained death following sudden onset of acute flu-like illness with haemorrhage, meningo-encephalitis, or visual loss during the preceding month."}, {"prompt": "What is the criteria for a suspected case of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Early disease: Acute febrile illness (axillary temperature >37.5 \u00b0C or oral temperature of >38.0\u00b0C) of more than 48 hours duration that does not respond to antibiotic or antimalarial therapy, and is associated with: Direct contact with sick or dead animal or its products AND / OR: Recent travel (during last week) to, or living in an area where, after heavy rains, livestock die or abort, and where RVF virus activity is suspected/confirmed AND / OR: Abrupt onset of any 1 or more of the following: exhaustion, backache, muscle pains, headache (often severe), discomfort when exposed to light, and nausea/vomiting AND / OR: Nausea/vomiting, diarrhoea OR abdominal pain with 1 or more of the following: Severe pallor (or Hb < 8 gm/dL), Low platelets (thrombocytopenia) as evidence by presence of small skin and mucous membrane haemorrhages (petechiae) (or platelet count < 100x109 / dL), Evidence of kidney failure (edema, reduced urine output) (or creatinine > 150 mol/L) AND / OR: Evidence of bleeding into skin, bleeding from puncture wounds, from mucous membranes or nose, from gastrointestinal tract and unnatural bleeding from vagina AND / OR: Clinical jaundice (3-fold increase above normal of transaminases). Late stages of diseases or complications (2-3 weeks after onset Patients who have experienced, in the preceding month a flu-like illness, with clinical criteria, who additionally develop the following: CNS manifestations which resemble meningo-encephalitis AND/OR: Unexplained visual loss OR: Unexplained death following sudden onset of acute flu-like illness with haemorrhage, meningo-encephalitis, or visual loss during the preceding month."}, {"prompt": "What are the clinical criteria for a suspected case of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Early disease: Acute febrile illness (axillary temperature >37.5 \u00b0C or oral temperature of >38.0\u00b0C) of more than 48 hours duration that does not respond to antibiotic or antimalarial therapy, and is associated with: Direct contact with sick or dead animal or its products AND / OR: Recent travel (during last week) to, or living in an area where, after heavy rains, livestock die or abort, and where RVF virus activity is suspected/confirmed AND / OR: Abrupt onset of any 1 or more of the following: exhaustion, backache, muscle pains, headache (often severe), discomfort when exposed to light, and nausea/vomiting AND / OR: Nausea/vomiting, diarrhoea OR abdominal pain with 1 or more of the following: Severe pallor (or Hb < 8 gm/dL), Low platelets (thrombocytopenia) as evidence by presence of small skin and mucous membrane haemorrhages (petechiae) (or platelet count < 100x109 / dL), Evidence of kidney failure (edema, reduced urine output) (or creatinine > 150 mol/L) AND / OR: Evidence of bleeding into skin, bleeding from puncture wounds, from mucous membranes or nose, from gastrointestinal tract and unnatural bleeding from vagina AND / OR: Clinical jaundice (3-fold increase above normal of transaminases). Late stages of diseases or complications (2-3 weeks after onset Patients who have experienced, in the preceding month a flu-like illness, with clinical criteria, who additionally develop the following: CNS manifestations which resemble meningo-encephalitis AND/OR: Unexplained visual loss OR: Unexplained death following sudden onset of acute flu-like illness with haemorrhage, meningo-encephalitis, or visual loss during the preceding month."}, {"prompt": "What are the components of the suspected case definition for Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Early disease: Acute febrile illness (axillary temperature >37.5 \u00b0C or oral temperature of >38.0\u00b0C) of more than 48 hours duration that does not respond to antibiotic or antimalarial therapy, and is associated with: Direct contact with sick or dead animal or its products AND / OR: Recent travel (during last week) to, or living in an area where, after heavy rains, livestock die or abort, and where RVF virus activity is suspected/confirmed AND / OR: Abrupt onset of any 1 or more of the following: exhaustion, backache, muscle pains, headache (often severe), discomfort when exposed to light, and nausea/vomiting AND / OR: Nausea/vomiting, diarrhoea OR abdominal pain with 1 or more of the following: Severe pallor (or Hb < 8 gm/dL), Low platelets (thrombocytopenia) as evidence by presence of small skin and mucous membrane haemorrhages (petechiae) (or platelet count < 100x109 / dL), Evidence of kidney failure (edema, reduced urine output) (or creatinine > 150 mol/L) AND / OR: Evidence of bleeding into skin, bleeding from puncture wounds, from mucous membranes or nose, from gastrointestinal tract and unnatural bleeding from vagina AND / OR: Clinical jaundice (3-fold increase above normal of transaminases). Late stages of diseases or complications (2-3 weeks after onset Patients who have experienced, in the preceding month a flu-like illness, with clinical criteria, who additionally develop the following: CNS manifestations which resemble meningo-encephalitis AND/OR: Unexplained visual loss OR: Unexplained death following sudden onset of acute flu-like illness with haemorrhage, meningo-encephalitis, or visual loss during the preceding month."}, {"prompt": "What is the standard case definition for a confirmed case of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Any patient who, after clinical screening, is positive for anti-RVF IgM ELISA antibodies (typically appear from fourth to sixth day after onset of symptoms) or tests positive on Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)."}, {"prompt": "What are the criteria for confirming a case of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Any patient who, after clinical screening, is positive for anti-RVF IgM ELISA antibodies (typically appear from fourth to sixth day after onset of symptoms) or tests positive on Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)."}, {"prompt": "How is a Rift Valley Fever (RVF) case confirmed? related to Yellow Fever Disease", "completion": "Any patient who, after clinical screening, is positive for anti-RVF IgM ELISA antibodies (typically appear from fourth to sixth day after onset of symptoms) or tests positive on Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)."}, {"prompt": "What are the diagnostic criteria for a confirmed case of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Any patient who, after clinical screening, is positive for anti-RVF IgM ELISA antibodies (typically appear from fourth to sixth day after onset of symptoms) or tests positive on Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)."}, {"prompt": "How should an alert be raised for Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels. Enhance the usual standard precautions throughout the health care setting. Treat and manage the patient with supportive care. Collect specimen safely to confirm the case."}, {"prompt": "What actions should be taken if a suspected case of Rift Valley Fever (RVF) is identified? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels. Enhance the usual standard precautions throughout the health care setting. Treat and manage the patient with supportive care. Collect specimen safely to confirm the case."}, {"prompt": "What should be done if a potential Rift Valley Fever (RVF) case is identified? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels. Enhance the usual standard precautions throughout the health care setting. Treat and manage the patient with supportive care. Collect specimen safely to confirm the case."}, {"prompt": "What is the immediate response to a suspected case of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels. Enhance the usual standard precautions throughout the health care setting. Treat and manage the patient with supportive care. Collect specimen safely to confirm the case."}, {"prompt": "What actions should be taken if a single case of Rift Valley Fever (RVF) is confirmed? related to Yellow Fever Disease", "completion": "If a single case is confirmed: Mobilize the community for early detection and care. Conduct community education about the confirmed case, how the disease is transmitted, and how to prevent contact with tissues of infected animals and avoid mosquito bites. Provide information about prevention in the home and when to seek care. Provide supportive treatment to all cases identified. Request additional help from national levels as needed. Collaborate with the animal health specialists to search and document cases among animals as well."}, {"prompt": "What should be done if a confirmed case of Rift Valley Fever (RVF) is identified? related to Yellow Fever Disease", "completion": "If a single case is confirmed: Mobilize the community for early detection and care. Conduct community education about the confirmed case, how the disease is transmitted, and how to prevent contact with tissues of infected animals and avoid mosquito bites. Provide information about prevention in the home and when to seek care. Provide supportive treatment to all cases identified. Request additional help from national levels as needed. Collaborate with the animal health specialists to search and document cases among animals as well."}, {"prompt": "How should data about a person with Rift Valley Fever (RVF) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths. During the outbreak, count and report cases and deaths. Analyze age and sex distribution. Assess risk factors immediately and consider request for assistance to improve outbreak control."}, {"prompt": "What is the approach to analyzing and interpreting data about Rift Valley Fever (RVF) cases? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths. During the outbreak, count and report cases and deaths. Analyze age and sex distribution. Assess risk factors immediately and consider request for assistance to improve outbreak control."}, {"prompt": "How is data about Rift Valley Fever (RVF) cases analyzed and interpreted? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths. During the outbreak, count and report cases and deaths. Analyze age and sex distribution. Assess risk factors immediately and consider request for assistance to improve outbreak control."}, {"prompt": "How is data about time in the context of Rift Valley Fever (RVF) analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases and deaths monthly. Construct an epidemic curve during the outbreak."}, {"prompt": "What methods are used to analyze and interpret the temporal data of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Graph cases and deaths monthly. Construct an epidemic curve during the outbreak."}, {"prompt": "How should time-related data on Rift Valley Fever (RVF) be analyzed? related to Yellow Fever Disease", "completion": "Graph cases and deaths monthly. Construct an epidemic curve during the outbreak."}, {"prompt": "How is data about place in the context of Rift Valley Fever (RVF) analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot location of case households and work sites using precise mapping."}, {"prompt": "What methods are used to analyze and interpret the spatial data of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Plot location of case households and work sites using precise mapping."}, {"prompt": "What are the approaches to analyzing the geographical data of Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Plot location of case households and work sites using precise mapping."}, {"prompt": "How is Rift Valley Fever (RVF) diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Acute RVF can be diagnosed using several different methods. Serological tests such as ELISA may confirm the presence of specific IgM antibodies to the virus. The virus itself may be detected in blood during the early phase of illness or in post-mortem tissue using a variety of techniques including, antigen detection tests by ELISA, RT-PCR, virus propagation (in cell cultures), Immunohistochemistry in formalin-fixed tissues. ELISA IgG can be used for retrospective diagnostic. Same test can be used for animal diagnosis."}, {"prompt": "What are the laboratory methods for diagnosing Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Acute RVF can be diagnosed using several different methods. Serological tests such as ELISA may confirm the presence of specific IgM antibodies to the virus. The virus itself may be detected in blood during the early phase of illness or in post-mortem tissue using a variety of techniques including, antigen detection tests by ELISA, RT-PCR, virus propagation (in cell cultures), Immunohistochemistry in formalin-fixed tissues. ELISA IgG can be used for retrospective diagnostic. Same test can be used for animal diagnosis."}, {"prompt": "What laboratory tests are conducted to diagnose Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "Acute RVF can be diagnosed using several different methods. Serological tests such as ELISA may confirm the presence of specific IgM antibodies to the virus. The virus itself may be detected in blood during the early phase of illness or in post-mortem tissue using a variety of techniques including, antigen detection tests by ELISA, RT-PCR, virus propagation (in cell cultures), Immunohistochemistry in formalin-fixed tissues. ELISA IgG can be used for retrospective diagnostic. Same test can be used for animal diagnosis."}, {"prompt": "What are the references for Rift Valley Fever (RVF)? related to Yellow Fever Disease", "completion": "1. WHO/EMC Infection control for VHF in the African health care setting, WHO, 1998.\n2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2.\n3. Fact sheet N\u00b0207 Revised September 2007.\n4. Infection Control for VHF in the African Health Care Setting /CDC (Annexes 11-12)"}, {"prompt": "Explain Rabies. related to Yellow Fever Disease", "completion": "The rabies virus infects the central nervous system, causing disease in the brain and, eventually, death. Early symptoms in people include: fever, headache, and general weakness or discomfort. As the disease progresses, symptoms include; insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, increase in saliva, difficulty swallowing, and fear of water."}, {"prompt": "Describe Rabies. related to Yellow Fever Disease", "completion": "The rabies virus infects the central nervous system, causing disease in the brain and, eventually, death. Early symptoms in people include: fever, headache, and general weakness or discomfort. As the disease progresses, symptoms include; insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, increase in saliva, difficulty swallowing, and fear of water."}, {"prompt": "Elaborate on Rabies. related to Yellow Fever Disease", "completion": "The rabies virus infects the central nervous system, causing disease in the brain and, eventually, death. Early symptoms in people include: fever, headache, and general weakness or discomfort. As the disease progresses, symptoms include; insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, increase in saliva, difficulty swallowing, and fear of water."}, {"prompt": "Define Rabies. related to Yellow Fever Disease", "completion": "The rabies virus infects the central nervous system, causing disease in the brain and, eventually, death. Early symptoms in people include: fever, headache, and general weakness or discomfort. As the disease progresses, symptoms include; insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, increase in saliva, difficulty swallowing, and fear of water."}, {"prompt": "What is the nature of Rabies? related to Yellow Fever Disease", "completion": "The rabies virus infects the central nervous system, causing disease in the brain and, eventually, death. Early symptoms in people include: fever, headache, and general weakness or discomfort. As the disease progresses, symptoms include; insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, increase in saliva, difficulty swallowing, and fear of water."}, {"prompt": "How does Rabies spread? related to Yellow Fever Disease", "completion": "Rabies is a zoonotic disease (a disease that is transmitted to humans from animals) that is caused by a virus. Rabies infects domestic and wild animals, and is spread to people through close contact with infected saliva (via bites or scratches). Dogs are the main carrier of rabies in Africa and are responsible for most (approximately 97%) of the human rabies deaths worldwide."}, {"prompt": "What are the modes of transmission for Rabies? related to Yellow Fever Disease", "completion": "Rabies is a zoonotic disease (a disease that is transmitted to humans from animals) that is caused by a virus. Rabies infects domestic and wild animals, and is spread to people through close contact with infected saliva (via bites or scratches). Dogs are the main carrier of rabies in Africa and are responsible for most (approximately 97%) of the human rabies deaths worldwide."}, {"prompt": "Why is Rabies a priority in global health efforts? related to Yellow Fever Disease", "completion": "In unvaccinated humans, rabies is almost always fatal if post-exposure prophylaxis is not administered before the onset of severe symptoms. Death usually occurs within days of the onset of neurological symptoms. WHO estimates approximately 55,000 human deaths worldwide due to rabies each year; in Africa the annual death toll is 24,000."}, {"prompt": "What makes Rabies a public health priority? related to Yellow Fever Disease", "completion": "In unvaccinated humans, rabies is almost always fatal if post-exposure prophylaxis is not administered before the onset of severe symptoms. Death usually occurs within days of the onset of neurological symptoms. WHO estimates approximately 55,000 human deaths worldwide due to rabies each year; in Africa the annual death toll is 24,000."}, {"prompt": "Who is most vulnerable to Rabies? related to Yellow Fever Disease", "completion": "People most at risk of rabies live in rural areas, and children are at highest risk of dog rabies. About 30% to 60% of the victims of dog bites (the primary mode of virus transmission) are children less than 15 years of age. Children often play with animals and are less likely to report bites or scratches."}, {"prompt": "What groups are most at risk of Rabies? related to Yellow Fever Disease", "completion": "People most at risk of rabies live in rural areas, and children are at highest risk of dog rabies. About 30% to 60% of the victims of dog bites (the primary mode of virus transmission) are children less than 15 years of age. Children often play with animals and are less likely to report bites or scratches."}, {"prompt": "Who is at high risk of contracting Rabies? related to Yellow Fever Disease", "completion": "People most at risk of rabies live in rural areas, and children are at highest risk of dog rabies. About 30% to 60% of the victims of dog bites (the primary mode of virus transmission) are children less than 15 years of age. Children often play with animals and are less likely to report bites or scratches."}, {"prompt": "What additional information is available on Rabies? related to Yellow Fever Disease", "completion": "Control of rabies in dog populations and access to human rabies post exposure prophylaxis can substantially reduce the burden of rabies in human populations. Rapid and accurate laboratory diagnosis of rabies in humans and other animals is essential for timely administration of post-exposure prophylaxis. Within a few hours, a diagnostic laboratory can determine whether or not an animal is rabid and inform the responsible medical personnel."}, {"prompt": "Is there any other important information about Rabies? related to Yellow Fever Disease", "completion": "Control of rabies in dog populations and access to human rabies post exposure prophylaxis can substantially reduce the burden of rabies in human populations. Rapid and accurate laboratory diagnosis of rabies in humans and other animals is essential for timely administration of post-exposure prophylaxis. Within a few hours, a diagnostic laboratory can determine whether or not an animal is rabid and inform the responsible medical personnel."}, {"prompt": "What are the main goals of Rabies surveillance? related to Yellow Fever Disease", "completion": "Detect and respond promptly and appropriately to cases and outbreaks of rabies. Identify high-risk areas. Estimation of disease burden. Immediate reporting of cases and routine monthly summary reports."}, {"prompt": "What is the objective of Rabies surveillance? related to Yellow Fever Disease", "completion": "Detect and respond promptly and appropriately to cases and outbreaks of rabies. Identify high-risk areas. Estimation of disease burden. Immediate reporting of cases and routine monthly summary reports."}, {"prompt": "How is a suspected case of Rabies defined? related to Yellow Fever Disease", "completion": "A person with one or more of the following: headache, neck pain, nausea, fever, fear of water, anxiety, agitation, abnormal tingling sensations or pain at the wound site, when contact with a rabid animal is suspected."}, {"prompt": "What are the criteria for suspected Rabies cases? related to Yellow Fever Disease", "completion": "A person with one or more of the following: headache, neck pain, nausea, fever, fear of water, anxiety, agitation, abnormal tingling sensations or pain at the wound site, when contact with a rabid animal is suspected."}, {"prompt": "When should Rabies be suspected? related to Yellow Fever Disease", "completion": "A person with one or more of the following: headache, neck pain, nausea, fever, fear of water, anxiety, agitation, abnormal tingling sensations or pain at the wound site, when contact with a rabid animal is suspected."}, {"prompt": "How is a confirmed Rabies case defined? related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed."}, {"prompt": "What is the definition of a confirmed Rabies case? related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed."}, {"prompt": "What are the recommended actions for Rabies control? related to Yellow Fever Disease", "completion": "For a single case: Post exposure prophylaxis to prevent rabies, Isolate patient if rabies develops to prevent infection of others, Immunize contacts if patient develops rabies, Vaccinate local dogs and cats to prevent outbreaks. General preventive measures: Promote public awareness of rabies, Target immunization campaign for domestic or wild animals in high-risk areas, Maintain active surveillance of rabies in animals."}, {"prompt": "What actions are advised for Rabies control? related to Yellow Fever Disease", "completion": "For a single case: Post exposure prophylaxis to prevent rabies, Isolate patient if rabies develops to prevent infection of others, Immunize contacts if patient develops rabies, Vaccinate local dogs and cats to prevent outbreaks. General preventive measures: Promote public awareness of rabies, Target immunization campaign for domestic or wild animals in high-risk areas, Maintain active surveillance of rabies in animals."}, {"prompt": "What measures can be taken to control Rabies? related to Yellow Fever Disease", "completion": "For a single case: Post exposure prophylaxis to prevent rabies, Isolate patient if rabies develops to prevent infection of others, Immunize contacts if patient develops rabies, Vaccinate local dogs and cats to prevent outbreaks. General preventive measures: Promote public awareness of rabies, Target immunization campaign for domestic or wild animals in high-risk areas, Maintain active surveillance of rabies in animals."}, {"prompt": "How should data about individuals with Rabies be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Analyze distribution of cases by age, exposing animal, and circumstances of infection. Assess risk factors to improve control of cases."}, {"prompt": "What methods are used for analyzing data about Rabies patients? related to Yellow Fever Disease", "completion": "Analyze distribution of cases by age, exposing animal, and circumstances of infection. Assess risk factors to improve control of cases."}, {"prompt": "How can data on Rabies cases be interpreted? related to Yellow Fever Disease", "completion": "Analyze distribution of cases by age, exposing animal, and circumstances of infection. Assess risk factors to improve control of cases."}, {"prompt": "How should data about time in the context of Rabies be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot cases monthly."}, {"prompt": "What are the temporal analysis methods for Rabies data? related to Yellow Fever Disease", "completion": "Plot cases monthly."}, {"prompt": "How can temporal analysis help in understanding Rabies patterns? related to Yellow Fever Disease", "completion": "Plot cases monthly."}, {"prompt": "How should data about place in the context of Rabies be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the location of case households and animal exposures."}, {"prompt": "What are the spatial analysis techniques for Rabies data? related to Yellow Fever Disease", "completion": "Plot the location of case households and animal exposures."}, {"prompt": "How can spatial analysis contribute to understanding Rabies transmission? related to Yellow Fever Disease", "completion": "Plot the location of case households and animal exposures."}, {"prompt": "What are the laboratory procedures for diagnosing Rabies? related to Yellow Fever Disease", "completion": "Detection of rabies viral antigens by direct fluorescent antibody (FA) in clinical specimens, preferably brain tissue (collected post mortem). Detection by FA on skin or corneal smear (collected ante mortem). FA positive after inoculation or brain tissue, saliva or CSF in cell culture, in mice or in suckling mice. Detectable rabies-neutralizing antibody titre in the CSF of an unvaccinated person. Identification of viral antigens by PCR on fixed tissue collected post modern or in a clinical specimen (brain tissue or skin, cornea or saliva). Isolation of rabies virus from clinical specimens and confirmation of rabies viral antigens by direct fluorescent antibody testing."}, {"prompt": "How is Rabies diagnosed using laboratory techniques? related to Yellow Fever Disease", "completion": "Detection of rabies viral antigens by direct fluorescent antibody (FA) in clinical specimens, preferably brain tissue (collected post mortem). Detection by FA on skin or corneal smear (collected ante mortem). FA positive after inoculation or brain tissue, saliva or CSF in cell culture, in mice or in suckling mice. Detectable rabies-neutralizing antibody titre in the CSF of an unvaccinated person. Identification of viral antigens by PCR on fixed tissue collected post modern or in a clinical specimen (brain tissue or skin, cornea or saliva). Isolation of rabies virus from clinical specimens and confirmation of rabies viral antigens by direct fluorescent antibody testing."}, {"prompt": "Where can I find references for Rabies? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2.\n2. Laboratory techniques in rabies, Fourth Edition, WHO, edited by F.-X. Meslin and all.\n3. World Health Organization, Rabies Fact Sheet http://www.who.int/mediacentre/factsheets/fs099/en/.\n4. Council of State and Territorial Epidemiologists (CSTE). National Surveillance for Human Rabies. CSTE position statement 09-ID-70. Atlanta: CSTE; June 2009. Available from: http://www.cste.org.\n5. Centers for Disease Control and Prevention (CDC). Human Rabies Prevention - United States, 2008: Recommendations of the Advisory Committee on Immunization Practices. MMWR 2008; 57(RR03):1-26, 28. Available from: http://www.cdc.gov/mmwr/.\n6. Bleck TP, Rupprecht CE. Chapter 160 - Rhabdoviruses. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and Practice of Infectious Diseases, 6th edition."}, {"prompt": "Where can I access references about Rabies? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2.\n2. Laboratory techniques in rabies, Fourth Edition, WHO, edited by F.-X. Meslin and all.\n3. World Health Organization, Rabies Fact Sheet http://www.who.int/mediacentre/factsheets/fs099/en/.\n4. Council of State and Territorial Epidemiologists (CSTE). National Surveillance for Human Rabies. CSTE position statement 09-ID-70. Atlanta: CSTE; June 2009. Available from: http://www.cste.org.\n5. Centers for Disease Control and Prevention (CDC). Human Rabies Prevention - United States, 2008: Recommendations of the Advisory Committee on Immunization Practices. MMWR 2008; 57(RR03):1-26, 28. Available from: http://www.cdc.gov/mmwr/.\n6. Bleck TP, Rupprecht CE. Chapter 160 - Rhabdoviruses. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and Practice of Infectious Diseases, 6th edition."}, {"prompt": "Explain Polio. related to Yellow Fever Disease", "completion": "Incubation period is 7 to 14 days for paralytic cases and the range is approximately 3 to 35 days. Poliovirus (genus Enterovirus) serotypes 1, 2, and 3 are transmitted from person-to-person via faecal-oral spread. The virus may be shed for several years by immuno-compromised persons. Infection is usually asymptomatic, but may cause a febrile syndrome with or without meningitis. In less than 5% of infections paralysis results, often of a single leg. Areas with low vaccine coverage may allow ongoing wild-type transmission. Paralytic polio, though not fatal, has devastating social and economic consequences among affected individuals. The Polio Eradication Program has nearly halted ongoing wild-type polio transmission worldwide through use of oral poliovirus (OPV) vaccine. Globally, poliovirus type 2 appears to have been eliminated. Serotypes 1 and 3 polioviruses still circulate in three endemic countries including Nigeria in Africa and surveillance is not yet adequate to assure eradication in many countries. Other neurological illnesses may cause AFP, for example, Guillain-Barre syndrome and transverse myelitis."}, {"prompt": "Define Polio. related to Yellow Fever Disease", "completion": "Incubation period is 7 to 14 days for paralytic cases and the range is approximately 3 to 35 days. Poliovirus (genus Enterovirus) serotypes 1, 2, and 3 are transmitted from person-to-person via faecal-oral spread. The virus may be shed for several years by immuno-compromised persons. Infection is usually asymptomatic, but may cause a febrile syndrome with or without meningitis. In less than 5% of infections paralysis results, often of a single leg. Areas with low vaccine coverage may allow ongoing wild-type transmission. Paralytic polio, though not fatal, has devastating social and economic consequences among affected individuals. The Polio Eradication Program has nearly halted ongoing wild-type polio transmission worldwide through use of oral poliovirus (OPV) vaccine. Globally, poliovirus type 2 appears to have been eliminated. Serotypes 1 and 3 polioviruses still circulate in three endemic countries including Nigeria in Africa and surveillance is not yet adequate to assure eradication in many countries. Other neurological illnesses may cause AFP, for example, Guillain-Barre syndrome and transverse myelitis."}, {"prompt": "What is the nature of Polio? related to Yellow Fever Disease", "completion": "Incubation period is 7 to 14 days for paralytic cases and the range is approximately 3 to 35 days. Poliovirus (genus Enterovirus) serotypes 1, 2, and 3 are transmitted from person-to-person via faecal-oral spread. The virus may be shed for several years by immuno-compromised persons. Infection is usually asymptomatic, but may cause a febrile syndrome with or without meningitis. In less than 5% of infections paralysis results, often of a single leg. Areas with low vaccine coverage may allow ongoing wild-type transmission. Paralytic polio, though not fatal, has devastating social and economic consequences among affected individuals. The Polio Eradication Program has nearly halted ongoing wild-type polio transmission worldwide through use of oral poliovirus (OPV) vaccine. Globally, poliovirus type 2 appears to have been eliminated. Serotypes 1 and 3 polioviruses still circulate in three endemic countries including Nigeria in Africa and surveillance is not yet adequate to assure eradication in many countries. Other neurological illnesses may cause AFP, for example, Guillain-Barre syndrome and transverse myelitis."}, {"prompt": "Describe Polio. related to Yellow Fever Disease", "completion": "Incubation period is 7 to 14 days for paralytic cases and the range is approximately 3 to 35 days. Poliovirus (genus Enterovirus) serotypes 1, 2, and 3 are transmitted from person-to-person via faecal-oral spread. The virus may be shed for several years by immuno-compromised persons. Infection is usually asymptomatic, but may cause a febrile syndrome with or without meningitis. In less than 5% of infections paralysis results, often of a single leg. Areas with low vaccine coverage may allow ongoing wild-type transmission. Paralytic polio, though not fatal, has devastating social and economic consequences among affected individuals. The Polio Eradication Program has nearly halted ongoing wild-type polio transmission worldwide through use of oral poliovirus (OPV) vaccine. Globally, poliovirus type 2 appears to have been eliminated. Serotypes 1 and 3 polioviruses still circulate in three endemic countries including Nigeria in Africa and surveillance is not yet adequate to assure eradication in many countries. Other neurological illnesses may cause AFP, for example, Guillain-Barre syndrome and transverse myelitis."}, {"prompt": "What is Polio? related to Yellow Fever Disease", "completion": "Incubation period is 7 to 14 days for paralytic cases and the range is approximately 3 to 35 days. Poliovirus (genus Enterovirus) serotypes 1, 2, and 3 are transmitted from person-to-person via faecal-oral spread. The virus may be shed for several years by immuno-compromised persons. Infection is usually asymptomatic, but may cause a febrile syndrome with or without meningitis. In less than 5% of infections paralysis results, often of a single leg. Areas with low vaccine coverage may allow ongoing wild-type transmission. Paralytic polio, though not fatal, has devastating social and economic consequences among affected individuals. The Polio Eradication Program has nearly halted ongoing wild-type polio transmission worldwide through use of oral poliovirus (OPV) vaccine. Globally, poliovirus type 2 appears to have been eliminated. Serotypes 1 and 3 polioviruses still circulate in three endemic countries including Nigeria in Africa and surveillance is not yet adequate to assure eradication in many countries. Other neurological illnesses may cause AFP, for example, Guillain-Barre syndrome and transverse myelitis."}, {"prompt": "Why is Polio a priority health concern? related to Yellow Fever Disease", "completion": "Infection is usually asymptomatic, but may cause a febrile syndrome with or without meningitis. In less than 5% of infections paralysis results, often of a single leg. Areas with low vaccine coverage may allow ongoing wild-type transmission."}, {"prompt": "What makes Polio a priority? related to Yellow Fever Disease", "completion": "Infection is usually asymptomatic, but may cause a febrile syndrome with or without meningitis. In less than 5% of infections paralysis results, often of a single leg. Areas with low vaccine coverage may allow ongoing wild-type transmission."}, {"prompt": "Why is Polio considered a major concern? related to Yellow Fever Disease", "completion": "Infection is usually asymptomatic, but may cause a febrile syndrome with or without meningitis. In less than 5% of infections paralysis results, often of a single leg. Areas with low vaccine coverage may allow ongoing wild-type transmission."}, {"prompt": "What are the surveillance objectives for Polio? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of all Acute Flaccid Paralysis cases. Weekly summary reporting of cases for routine surveillance and outbreaks. Detect cases of acute flaccid paralysis (AFP) and obtain laboratory confirmation of the aetiology of all suspected AFP cases. Obtain two stool specimens within 14 days of the onset of paralysis for viral isolation. Surveillance for AFP is used to capture all true cases of paralytic poliomyelitis. Target for surveillance performance to provide certification of polio eradications is 4 cases of AFP per year per 100 000 population aged less than 15 years."}, {"prompt": "What is the purpose of Polio surveillance? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of all Acute Flaccid Paralysis cases. Weekly summary reporting of cases for routine surveillance and outbreaks. Detect cases of acute flaccid paralysis (AFP) and obtain laboratory confirmation of the aetiology of all suspected AFP cases. Obtain two stool specimens within 14 days of the onset of paralysis for viral isolation. Surveillance for AFP is used to capture all true cases of paralytic poliomyelitis. Target for surveillance performance to provide certification of polio eradications is 4 cases of AFP per year per 100 000 population aged less than 15 years."}, {"prompt": "What are the surveillance targets for Polio? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of all Acute Flaccid Paralysis cases. Weekly summary reporting of cases for routine surveillance and outbreaks. Detect cases of acute flaccid paralysis (AFP) and obtain laboratory confirmation of the aetiology of all suspected AFP cases. Obtain two stool specimens within 14 days of the onset of paralysis for viral isolation. Surveillance for AFP is used to capture all true cases of paralytic poliomyelitis. Target for surveillance performance to provide certification of polio eradications is 4 cases of AFP per year per 100 000 population aged less than 15 years."}, {"prompt": "What is the standard case definition for a suspected new case of Polio? related to Yellow Fever Disease", "completion": "Any child under 15 years of age with acute flaccid paralysis or any person with paralytic illness at any age in whom the clinician suspects poliomyelitis."}, {"prompt": "How is a suspected new case of Polio defined? related to Yellow Fever Disease", "completion": "Any child under 15 years of age with acute flaccid paralysis or any person with paralytic illness at any age in whom the clinician suspects poliomyelitis."}, {"prompt": "What criteria indicate a suspected new case of Polio? related to Yellow Fever Disease", "completion": "Any child under 15 years of age with acute flaccid paralysis or any person with paralytic illness at any age in whom the clinician suspects poliomyelitis."}, {"prompt": "What is the standard case definition for a confirmed case of Polio? related to Yellow Fever Disease", "completion": "A suspected case with virus isolation in stool."}, {"prompt": "How is a confirmed case of Polio defined? related to Yellow Fever Disease", "completion": "A suspected case with virus isolation in stool."}, {"prompt": "What criteria are used to confirm a case of Polio? related to Yellow Fever Disease", "completion": "A suspected case with virus isolation in stool."}, {"prompt": "When should an alert be raised for Polio? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report the suspected case immediately according to the national polio eradication program guidelines, Conduct a case-based investigation. Include a vaccination history for the patient, Collect two stool specimens. Collect the first one when the case is investigated. Collect the second one from the same patient 24 to 48 hours later. See laboratory guidelines for information on how to prepare, store and transport the specimen. If identified beyond 14 days of onset of paralysis collect two stool specimens from at least 3- 5 contacts of the AFP case. Obtain virological data from reference laboratory to confirm wild-type poliomyelitis or VAPP."}, {"prompt": "Under what circumstances should an alert be raised for Polio? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report the suspected case immediately according to the national polio eradication program guidelines, Conduct a case-based investigation. Include a vaccination history for the patient, Collect two stool specimens. Collect the first one when the case is investigated. Collect the second one from the same patient 24 to 48 hours later. See laboratory guidelines for information on how to prepare, store and transport the specimen. If identified beyond 14 days of onset of paralysis collect two stool specimens from at least 3- 5 contacts of the AFP case. Obtain virological data from reference laboratory to confirm wild-type poliomyelitis or VAPP."}, {"prompt": "What actions should be taken if a single case of Polio is confirmed? related to Yellow Fever Disease", "completion": "If wild polio virus is isolated from stool specimen, refer to national polio eradication program guidelines for recommended response actions. The national level will decide which actions to take. They may include the following: Specify reasons for non-vaccination of each unvaccinated case and address the identified deficiencies. Immediately conduct 'mopping-up' vaccination campaign around the vicinity of the case, Conduct surveys to identify areas of low OPV coverage during routine EPI activities, and improve routine vaccine coverage of OPV and other EPI antigens. Lead supplemental vaccination campaigns during National Immunization Days (NIDs) or Sub-National Immunization Days (SNIDs). Focus supplemental vaccination activities in areas of low vaccine coverage during EPI. Consider use of house-to-house vaccination teams in selected areas."}, {"prompt": "What should be done if a single case of Polio is confirmed? related to Yellow Fever Disease", "completion": "If wild polio virus is isolated from stool specimen, refer to national polio eradication program guidelines for recommended response actions. The national level will decide which actions to take. They may include the following: Specify reasons for non-vaccination of each unvaccinated case and address the identified deficiencies. Immediately conduct 'mopping-up' vaccination campaign around the vicinity of the case, Conduct surveys to identify areas of low OPV coverage during routine EPI activities, and improve routine vaccine coverage of OPV and other EPI antigens. Lead supplemental vaccination campaigns during National Immunization Days (NIDs) or Sub-National Immunization Days (SNIDs). Focus supplemental vaccination activities in areas of low vaccine coverage during EPI. Consider use of house-to-house vaccination teams in selected areas."}, {"prompt": "What actions should be taken in response to a confirmed Polio case? related to Yellow Fever Disease", "completion": "If wild polio virus is isolated from stool specimen, refer to national polio eradication program guidelines for recommended response actions. The national level will decide which actions to take. They may include the following: Specify reasons for non-vaccination of each unvaccinated case and address the identified deficiencies. Immediately conduct 'mopping-up' vaccination campaign around the vicinity of the case, Conduct surveys to identify areas of low OPV coverage during routine EPI activities, and improve routine vaccine coverage of OPV and other EPI antigens. Lead supplemental vaccination campaigns during National Immunization Days (NIDs) or Sub-National Immunization Days (SNIDs). Focus supplemental vaccination activities in areas of low vaccine coverage during EPI. Consider use of house-to-house vaccination teams in selected areas."}, {"prompt": "How should data about a person with Polio be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count monthly routine and outbreak-related cases. Analyze age distribution. Assess risk factors for low vaccine coverage."}, {"prompt": "What is the process for analyzing and interpreting data about a person with Polio? related to Yellow Fever Disease", "completion": "Count monthly routine and outbreak-related cases. Analyze age distribution. Assess risk factors for low vaccine coverage."}, {"prompt": "How should data about time in the context of Polio be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph weekly cases (which should be zero to very few cases per area per year), or weekly cases during an outbreak. Evaluate the percent of suspected cases reported within 48 hours and the percentage with adequate laboratory evaluation."}, {"prompt": "What is the process for analyzing and interpreting data about time in the context of Polio? related to Yellow Fever Disease", "completion": "Graph weekly cases (which should be zero to very few cases per area per year), or weekly cases during an outbreak. Evaluate the percent of suspected cases reported within 48 hours and the percentage with adequate laboratory evaluation."}, {"prompt": "How should data about place in the context of Polio be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot location of case households. Investigate the circumstances of poliovirus transmission in each case thoroughly. Examine the possibility of other potential areas of transmission."}, {"prompt": "What is the process for analyzing and interpreting data about place in the context of Polio? related to Yellow Fever Disease", "completion": "Plot location of case households. Investigate the circumstances of poliovirus transmission in each case thoroughly. Examine the possibility of other potential areas of transmission."}, {"prompt": "How is Polio diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Isolation of polio virus from stool is the diagnostic test for Polio. The specimen required is Stool. Note: If no specimen is collected, re-evaluate patient after 60 days to confirm clinical diagnosis of polio (AFP). Collect a sample from every suspected AFP case. Collect the first specimen when the case is investigated. Collect a second specimen on the same patient 24 to 48 hours later. Place stool in clean, leak-proof container and label clearly; Immediately place in refrigerator or cold box not used for storing vaccines or other medicines; Transport specimens so they will arrive at designated polio laboratory within 72 hours of collection. When there is a delay, and specimen will not be transported within 72 hours, freeze specimen at -20C or colder. Then transport frozen specimen with dry ice or cold packs also frozen at -20C or colder. Confirmed results are usually available within 21 after receipt of specimen by the laboratory. If wild or vaccine derived polio virus is detected, the national program will plan appropriate response actions."}, {"prompt": "What laboratory procedures are used to diagnose Polio? related to Yellow Fever Disease", "completion": "Isolation of polio virus from stool is the diagnostic test for Polio. The specimen required is Stool. Note: If no specimen is collected, re-evaluate patient after 60 days to confirm clinical diagnosis of polio (AFP). Collect a sample from every suspected AFP case. Collect the first specimen when the case is investigated. Collect a second specimen on the same patient 24 to 48 hours later. Place stool in clean, leak-proof container and label clearly; Immediately place in refrigerator or cold box not used for storing vaccines or other medicines; Transport specimens so they will arrive at designated polio laboratory within 72 hours of collection. When there is a delay, and specimen will not be transported within 72 hours, freeze specimen at -20C or colder. Then transport frozen specimen with dry ice or cold packs also frozen at -20C or colder. Confirmed results are usually available within 21 after receipt of specimen by the laboratory. If wild or vaccine derived polio virus is detected, the national program will plan appropriate response actions."}, {"prompt": "What are the references for Polio? related to Yellow Fever Disease", "completion": "1. Field guide for training operational level health workers on vaccine preventable disease surveillance, MoH/ UNEPI (Revised edition 2012)\n2. Field Guide for Supplementary Activities Aimed at Achieving Polio Eradication. World Health Organization\n3. WHO global action plan for laboratory containment of wild polioviruses. WHO/V&B/99.32, Geneva, 1999\n4. Manual for the virological investigation of polio,WHO/ EPI/GEN/97.01, Geneva, 2004\n5. Supplement to the Manual for the virological investigation of Polio- WHO/EPI 2007"}, {"prompt": "What are the sources for information about Polio? related to Yellow Fever Disease", "completion": "1. Field guide for training operational level health workers on vaccine preventable disease surveillance, MoH/ UNEPI (Revised edition 2012)\n2. Field Guide for Supplementary Activities Aimed at Achieving Polio Eradication. World Health Organization\n3. WHO global action plan for laboratory containment of wild polioviruses. WHO/V&B/99.32, Geneva, 1999\n4. Manual for the virological investigation of polio,WHO/ EPI/GEN/97.01, Geneva, 2004\n5. Supplement to the Manual for the virological investigation of Polio- WHO/EPI 2007"}, {"prompt": "Define Plague. related to Yellow Fever Disease", "completion": "Zoonotic systemic bacterial infection caused by Yersinia pestis (plague bacillus) usually transmitted to humans by rodents and their fleas. Main disease forms: bubonic, pneumonic, and septicaemic; large-scale epidemics may occur in urban or rural settings."}, {"prompt": "What is the nature of Plague? related to Yellow Fever Disease", "completion": "Zoonotic systemic bacterial infection caused by Yersinia pestis (plague bacillus) usually transmitted to humans by rodents and their fleas. Main disease forms: bubonic, pneumonic, and septicaemic; large-scale epidemics may occur in urban or rural settings."}, {"prompt": "Describe Plague. related to Yellow Fever Disease", "completion": "Zoonotic systemic bacterial infection caused by Yersinia pestis (plague bacillus) usually transmitted to humans by rodents and their fleas. Main disease forms: bubonic, pneumonic, and septicaemic; large-scale epidemics may occur in urban or rural settings."}, {"prompt": "Elaborate on Plague. related to Yellow Fever Disease", "completion": "Zoonotic systemic bacterial infection caused by Yersinia pestis (plague bacillus) usually transmitted to humans by rodents and their fleas. Main disease forms: bubonic, pneumonic, and septicaemic; large-scale epidemics may occur in urban or rural settings."}, {"prompt": "Explain Plague. related to Yellow Fever Disease", "completion": "Zoonotic systemic bacterial infection caused by Yersinia pestis (plague bacillus) usually transmitted to humans by rodents and their fleas. Main disease forms: bubonic, pneumonic, and septicaemic; large-scale epidemics may occur in urban or rural settings."}, {"prompt": "How is Plague transmitted? related to Yellow Fever Disease", "completion": "Exposure to infected populations of wild or domesticated rodents and their fleas."}, {"prompt": "What is the mode of transmission of Plague? related to Yellow Fever Disease", "completion": "Exposure to infected populations of wild or domesticated rodents and their fleas."}, {"prompt": "Explain the transmission of Plague. related to Yellow Fever Disease", "completion": "Exposure to infected populations of wild or domesticated rodents and their fleas."}, {"prompt": "Why is Plague a public health priority? related to Yellow Fever Disease", "completion": "Case fatality rate (CFR) may exceed 50-60% in untreated bubonic plague and approaches 100% in untreated pneumonic or septicaemic plague, but is usually <1% with appropriate treatment."}, {"prompt": "What makes Plague a priority in public health efforts? related to Yellow Fever Disease", "completion": "Case fatality rate (CFR) may exceed 50-60% in untreated bubonic plague and approaches 100% in untreated pneumonic or septicaemic plague, but is usually <1% with appropriate treatment."}, {"prompt": "What factors contribute to Plague being a public health priority? related to Yellow Fever Disease", "completion": "Case fatality rate (CFR) may exceed 50-60% in untreated bubonic plague and approaches 100% in untreated pneumonic or septicaemic plague, but is usually <1% with appropriate treatment."}, {"prompt": "What are the risk factors for Plague? related to Yellow Fever Disease", "completion": "Risk factor: rural residence. Exposure to infected populations of wild or domesticated rodents and their fleas."}, {"prompt": "Who is at risk for Plague? related to Yellow Fever Disease", "completion": "Risk factor: rural residence. Exposure to infected populations of wild or domesticated rodents and their fleas."}, {"prompt": "What populations are vulnerable to Plague? related to Yellow Fever Disease", "completion": "Risk factor: rural residence. Exposure to infected populations of wild or domesticated rodents and their fleas."}, {"prompt": "What additional information is available about Plague? related to Yellow Fever Disease", "completion": "Incubation period is 1 to 7 days."}, {"prompt": "What else do we know about Plague? related to Yellow Fever Disease", "completion": "Incubation period is 1 to 7 days."}, {"prompt": "Tell me more about Plague. related to Yellow Fever Disease", "completion": "Incubation period is 1 to 7 days."}, {"prompt": "What are the surveillance objectives for Plague? related to Yellow Fever Disease", "completion": "Detect outbreaks of plague promptly. Verify aetiology of all suspected non-outbreak-related cases and the first 5 to 10 outbreak-related cases."}, {"prompt": "What is the purpose of Plague surveillance? related to Yellow Fever Disease", "completion": "Detect outbreaks of plague promptly. Verify aetiology of all suspected non-outbreak-related cases and the first 5 to 10 outbreak-related cases."}, {"prompt": "How is a suspected case of Plague defined? related to Yellow Fever Disease", "completion": "Any person with sudden onset of fever, chills, headache, severe malaise, prostration and very painful swelling of lymph nodes, or cough with blood stained sputum, chest pain, and difficulty in breathing."}, {"prompt": "What are the criteria for suspecting a case of Plague? related to Yellow Fever Disease", "completion": "Any person with sudden onset of fever, chills, headache, severe malaise, prostration and very painful swelling of lymph nodes, or cough with blood stained sputum, chest pain, and difficulty in breathing."}, {"prompt": "When should an alert be raised for Plague? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information to the next level,Collect specimen for confirming the case, Investigate the case, Treat the patient with streptomycin, gentamicin or chloramphenicol, and administer chemoprophylaxis of close contacts with tetracycline for seven days from time of last exposure."}, {"prompt": "What should be done in response to an alert for Plague? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information to the next level,Collect specimen for confirming the case, Investigate the case, Treat the patient with streptomycin, gentamicin or chloramphenicol, and administer chemoprophylaxis of close contacts with tetracycline for seven days from time of last exposure."}, {"prompt": "What actions should be taken if a single case of Plague is confirmed? related to Yellow Fever Disease", "completion": "If the suspected case is confirmed: Isolate patients and contacts of pneumonic plague with precautions against airborne spread (wear masks, for example) until at least after 48 hours of appropriate antibiotic therapy,Mobilize community to enable rapid case detection and treatment, and to recognize mass rodent die-off as a sign of possible impending epidemic, Identify high risk population groups through person, place, and time analysis. Reduce sporadic and outbreak-related cases via improved control or rodent populations (remove trash, food sources, and rat harbourages) and protect against fleas with insect repellent on skin and clothing and environmental flea control (especially in homes and seaports and airports)."}, {"prompt": "What steps should be taken if a single case of Plague is confirmed? related to Yellow Fever Disease", "completion": "If the suspected case is confirmed: Isolate patients and contacts of pneumonic plague with precautions against airborne spread (wear masks, for example) until at least after 48 hours of appropriate antibiotic therapy,Mobilize community to enable rapid case detection and treatment, and to recognize mass rodent die-off as a sign of possible impending epidemic, Identify high risk population groups through person, place, and time analysis. Reduce sporadic and outbreak-related cases via improved control or rodent populations (remove trash, food sources, and rat harbourages) and protect against fleas with insect repellent on skin and clothing and environmental flea control (especially in homes and seaports and airports)."}, {"prompt": "How should data about a person with Plague be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths for routine surveillance. Count weekly cases and deaths for outbreaks. Analyze age distribution and assess risk factors to improve control of sporadic disease and outbreaks."}, {"prompt": "What methods are used to analyze data about individuals with Plague? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths for routine surveillance. Count weekly cases and deaths for outbreaks. Analyze age distribution and assess risk factors to improve control of sporadic disease and outbreaks."}, {"prompt": "How can we interpret the data on Plague cases and individuals? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths for routine surveillance. Count weekly cases and deaths for outbreaks. Analyze age distribution and assess risk factors to improve control of sporadic disease and outbreaks."}, {"prompt": "How should data about time in the context of Plague be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph monthly trends in cases and deaths. Construct epidemic curve for outbreak cases."}, {"prompt": "What are the techniques used for temporal analysis of Plague cases? related to Yellow Fever Disease", "completion": "Graph monthly trends in cases and deaths. Construct epidemic curve for outbreak cases."}, {"prompt": "How can temporal analysis help in understanding Plague trends? related to Yellow Fever Disease", "completion": "Graph monthly trends in cases and deaths. Construct epidemic curve for outbreak cases."}, {"prompt": "How should data about place in the context of Plague be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "What are the methods used for spatial analysis of Plague cases? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "How can spatial analysis contribute to understanding Plague transmission? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "How is Plague diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Isolation of Yersinia pestis from bubo aspirate or from culture of blood, CSF or sputum. Identification of antibodies to the Y. pestis F1 antigen from serum. Specimens should be collected using aseptic techniques. Materials for culture should be sent to the laboratory in Cary Blair transport media or frozen (preferably with dry ice (frozen CO2). Unpreserved specimens should reach the laboratory the same day. Liquid specimens (aspirates) should be absorbed with a sterile cotton swab and placed into Cary-Blair transport medium. Refrigerate. If transport will require 24 or more hours and Cary Blair transport is not available, freeze the specimen and transport it frozen with cool packs."}, {"prompt": "What are the laboratory procedures for diagnosing Plague? related to Yellow Fever Disease", "completion": "Isolation of Yersinia pestis from bubo aspirate or from culture of blood, CSF or sputum. Identification of antibodies to the Y. pestis F1 antigen from serum. Specimens should be collected using aseptic techniques. Materials for culture should be sent to the laboratory in Cary Blair transport media or frozen (preferably with dry ice (frozen CO2). Unpreserved specimens should reach the laboratory the same day. Liquid specimens (aspirates) should be absorbed with a sterile cotton swab and placed into Cary-Blair transport medium. Refrigerate. If transport will require 24 or more hours and Cary Blair transport is not available, freeze the specimen and transport it frozen with cool packs."}, {"prompt": "What are the references for Plague? related to Yellow Fever Disease", "completion": "1. Plague Manual: Epidemiology, Distribution, Surveillance and Control/ Manuel de la Peste: Epid\u00e9miologie, R\u00e9partition, Surveillance et Lutte. WHO/CDS/CSR/EDC/99.2 Laboratory Manual of Plague Diagnostic tests. CDC/WHO publication, 2000, Atlanta, GA."}, {"prompt": "Where can I find more information about Plague? related to Yellow Fever Disease", "completion": "1. Plague Manual: Epidemiology, Distribution, Surveillance and Control/ Manuel de la Peste: Epid\u00e9miologie, R\u00e9partition, Surveillance et Lutte. WHO/CDS/CSR/EDC/99.2 Laboratory Manual of Plague Diagnostic tests. CDC/WHO publication, 2000, Atlanta, GA."}, {"prompt": "Define Perinatal Deaths. related to Yellow Fever Disease", "completion": "Perinatal mortality refers to the number of stillbirths and deaths in the first week of life (early neonatal mortality). The perinatal period commences at 28 completed weeks of gestation and ends seven completed days after birth. Perinatal and maternal health are closely linked."}, {"prompt": "What is the meaning of Perinatal Deaths? related to Yellow Fever Disease", "completion": "Perinatal mortality refers to the number of stillbirths and deaths in the first week of life (early neonatal mortality). The perinatal period commences at 28 completed weeks of gestation and ends seven completed days after birth. Perinatal and maternal health are closely linked."}, {"prompt": "Explain Perinatal Deaths. related to Yellow Fever Disease", "completion": "Perinatal mortality refers to the number of stillbirths and deaths in the first week of life (early neonatal mortality). The perinatal period commences at 28 completed weeks of gestation and ends seven completed days after birth. Perinatal and maternal health are closely linked."}, {"prompt": "Describe Perinatal Deaths. related to Yellow Fever Disease", "completion": "Perinatal mortality refers to the number of stillbirths and deaths in the first week of life (early neonatal mortality). The perinatal period commences at 28 completed weeks of gestation and ends seven completed days after birth. Perinatal and maternal health are closely linked."}, {"prompt": "What does Perinatal Deaths mean? related to Yellow Fever Disease", "completion": "Perinatal mortality refers to the number of stillbirths and deaths in the first week of life (early neonatal mortality). The perinatal period commences at 28 completed weeks of gestation and ends seven completed days after birth. Perinatal and maternal health are closely linked."}, {"prompt": "Why is Perinatal Deaths a global health priority? related to Yellow Fever Disease", "completion": "In 2009, there were 2.6 million stillbirths globally with more than 8200 deaths a day. At least half of all stillbirths occurred in the intrapartum period."}, {"prompt": "What makes Perinatal Deaths a priority in global health efforts? related to Yellow Fever Disease", "completion": "In 2009, there were 2.6 million stillbirths globally with more than 8200 deaths a day. At least half of all stillbirths occurred in the intrapartum period."}, {"prompt": "What are the reasons behind Perinatal Deaths being a global health priority? related to Yellow Fever Disease", "completion": "In 2009, there were 2.6 million stillbirths globally with more than 8200 deaths a day. At least half of all stillbirths occurred in the intrapartum period."}, {"prompt": "Who is at the highest risk of Perinatal Deaths? related to Yellow Fever Disease", "completion": "About 80% of perinatal deaths are due to births asphyxia, complications due to prematurity and infections. Other factors underlying prenatal deaths are maternal conditions such as poor obstetric care, malaria, HIV. Quality skilled care during pregnancy and childbirth are key for the health of the baby."}, {"prompt": "Which group of individuals are most susceptible to Perinatal Deaths? related to Yellow Fever Disease", "completion": "About 80% of perinatal deaths are due to births asphyxia, complications due to prematurity and infections. Other factors underlying prenatal deaths are maternal conditions such as poor obstetric care, malaria, HIV. Quality skilled care during pregnancy and childbirth are key for the health of the baby."}, {"prompt": "What factors increase the risk of Perinatal Deaths? related to Yellow Fever Disease", "completion": "About 80% of perinatal deaths are due to births asphyxia, complications due to prematurity and infections. Other factors underlying prenatal deaths are maternal conditions such as poor obstetric care, malaria, HIV. Quality skilled care during pregnancy and childbirth are key for the health of the baby."}, {"prompt": "What additional information is available about Perinatal Deaths in Uganda? related to Yellow Fever Disease", "completion": "In Uganda, the perinatal deaths are estimated to be 29 per 1000 live births (UDHS, 2011)."}, {"prompt": "Can you provide more details about Perinatal Deaths in Uganda? related to Yellow Fever Disease", "completion": "In Uganda, the perinatal deaths are estimated to be 29 per 1000 live births (UDHS, 2011)."}, {"prompt": "What are the specific statistics for Perinatal Deaths in Uganda? related to Yellow Fever Disease", "completion": "In Uganda, the perinatal deaths are estimated to be 29 per 1000 live births (UDHS, 2011)."}, {"prompt": "What are the surveillance objectives for Perinatal Deaths? related to Yellow Fever Disease", "completion": "Estimate and monitor perinatal deaths including still births. Identify risk factors and high risk area for perinatal death including still births to inform program decisions. Evaluate programmes aimed at reducing perinatal/newborn deaths."}, {"prompt": "What are the goals of Perinatal Deaths surveillance? related to Yellow Fever Disease", "completion": "Estimate and monitor perinatal deaths including still births. Identify risk factors and high risk area for perinatal death including still births to inform program decisions. Evaluate programmes aimed at reducing perinatal/newborn deaths."}, {"prompt": "What are the targets for Perinatal Deaths surveillance? related to Yellow Fever Disease", "completion": "Estimate and monitor perinatal deaths including still births. Identify risk factors and high risk area for perinatal death including still births to inform program decisions. Evaluate programmes aimed at reducing perinatal/newborn deaths."}, {"prompt": "What is the standard case definition for Perinatal Deaths? related to Yellow Fever Disease", "completion": "Death of a baby that occurred around the time of birth, including both: Death of a newborn occurring during the first seven days of life and Stillbirth (death prior to the complete expulsion or extraction from its mother of a fetus/baby of 28 or more weeks of gestation; indicated by failure to breathe or show any other evidence of life, such as beating of the heart, pulsation of the umbilical cord or definite movement of voluntary muscles after such separation of the fetus)."}, {"prompt": "How is Perinatal Deaths defined? related to Yellow Fever Disease", "completion": "Death of a baby that occurred around the time of birth, including both: Death of a newborn occurring during the first seven days of life and Stillbirth (death prior to the complete expulsion or extraction from its mother of a fetus/baby of 28 or more weeks of gestation; indicated by failure to breathe or show any other evidence of life, such as beating of the heart, pulsation of the umbilical cord or definite movement of voluntary muscles after such separation of the fetus)."}, {"prompt": "When is a case considered Perinatal Death? related to Yellow Fever Disease", "completion": "Death of a baby that occurred around the time of birth, including both: Death of a newborn occurring during the first seven days of life and Stillbirth (death prior to the complete expulsion or extraction from its mother of a fetus/baby of 28 or more weeks of gestation; indicated by failure to breathe or show any other evidence of life, such as beating of the heart, pulsation of the umbilical cord or definite movement of voluntary muscles after such separation of the fetus)."}, {"prompt": "What are the recommended public health actions to address Perinatal Deaths? related to Yellow Fever Disease", "completion": "Monitor trends of perinatal deaths including still births, Promote public awareness and educate the community about predisposing factors and how to prevent them, Advocate for and implement low cost maternal newborn high impact interventions along the continuum of care and contribute to social economic growth and the attainment of human right, Identify high risk areas and communities."}, {"prompt": "What actions can be taken at the public health level to reduce Perinatal Deaths? related to Yellow Fever Disease", "completion": "Monitor trends of perinatal deaths including still births, Promote public awareness and educate the community about predisposing factors and how to prevent them, Advocate for and implement low cost maternal newborn high impact interventions along the continuum of care and contribute to social economic growth and the attainment of human right, Identify high risk areas and communities."}, {"prompt": "How should data about a person with Perinatal Deaths be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Analyse the distribution of cases by age and or weight and other demographic factors."}, {"prompt": "What data analysis methods are used for individuals with Perinatal Deaths? related to Yellow Fever Disease", "completion": "Analyse the distribution of cases by age and or weight and other demographic factors."}, {"prompt": "How can data about a person with Perinatal Deaths be interpreted? related to Yellow Fever Disease", "completion": "Analyse the distribution of cases by age and or weight and other demographic factors."}, {"prompt": "How should data about time in the context of Perinatal Deaths be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends."}, {"prompt": "What are the techniques for temporal analysis of Perinatal Deaths? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends."}, {"prompt": "How can temporal analysis help in understanding Perinatal Deaths trends? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends."}, {"prompt": "How should data about place in the context of Perinatal Deaths be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the location of cases and analyze the distribution."}, {"prompt": "What are the methods used for spatial analysis of Perinatal Deaths? related to Yellow Fever Disease", "completion": "Plot the location of cases and analyze the distribution."}, {"prompt": "How can spatial analysis contribute to understanding Perinatal Deaths distribution? related to Yellow Fever Disease", "completion": "Plot the location of cases and analyze the distribution."}, {"prompt": "What are the laboratory procedures for diagnosing Perinatal Deaths? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "Is laboratory confirmation necessary for diagnosing Perinatal Deaths? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "Do we need laboratory confirmation to diagnose Perinatal Deaths? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "What are the references for Perinatal Deaths? related to Yellow Fever Disease", "completion": "1. World Health Organization - Maternal and Perinatal Health. [Link](http://www.who.int/maternal_child_adolescent/topics/maternal/maternal_perinatal/en/)"}, {"prompt": "Where can I find more information about Perinatal Deaths? related to Yellow Fever Disease", "completion": "1. World Health Organization - Maternal and Perinatal Health. [Link](http://www.who.int/maternal_child_adolescent/topics/maternal/maternal_perinatal/en/)"}, {"prompt": "Explain Onchocerciasis. related to Yellow Fever Disease", "completion": "Filarial infection of the skin and eye caused by Onchocerca volvulus transmitted by the bite of female Simulium black flies. Incubation period is years to decades since repeated infection is necessary for disease manifestations. Clinical illness is unusual in children even in endemic areas. Other filaria (for example, Loa loa and Mansonella) and other chronic skin and eye disease can produce similar clinical findings."}, {"prompt": "Describe Onchocerciasis. related to Yellow Fever Disease", "completion": "Filarial infection of the skin and eye caused by Onchocerca volvulus transmitted by the bite of female Simulium black flies. Incubation period is years to decades since repeated infection is necessary for disease manifestations. Clinical illness is unusual in children even in endemic areas. Other filaria (for example, Loa loa and Mansonella) and other chronic skin and eye disease can produce similar clinical findings."}, {"prompt": "Elaborate on Onchocerciasis. related to Yellow Fever Disease", "completion": "Filarial infection of the skin and eye caused by Onchocerca volvulus transmitted by the bite of female Simulium black flies. Incubation period is years to decades since repeated infection is necessary for disease manifestations. Clinical illness is unusual in children even in endemic areas. Other filaria (for example, Loa loa and Mansonella) and other chronic skin and eye disease can produce similar clinical findings."}, {"prompt": "Define Onchocerciasis. related to Yellow Fever Disease", "completion": "Filarial infection of the skin and eye caused by Onchocerca volvulus transmitted by the bite of female Simulium black flies. Incubation period is years to decades since repeated infection is necessary for disease manifestations. Clinical illness is unusual in children even in endemic areas. Other filaria (for example, Loa loa and Mansonella) and other chronic skin and eye disease can produce similar clinical findings."}, {"prompt": "What is the nature of Onchocerciasis? related to Yellow Fever Disease", "completion": "Filarial infection of the skin and eye caused by Onchocerca volvulus transmitted by the bite of female Simulium black flies. Incubation period is years to decades since repeated infection is necessary for disease manifestations. Clinical illness is unusual in children even in endemic areas. Other filaria (for example, Loa loa and Mansonella) and other chronic skin and eye disease can produce similar clinical findings."}, {"prompt": "Why is Onchocerciasis a global health priority? related to Yellow Fever Disease", "completion": "Nearly the entire world's estimated 18 million infected persons (of whom more than 250,000 are blind) live within 26 African countries. Onchocerciasis is the second leading infectious cause of blindness worldwide. It causes debilitating skin problems, leading to significant decreases in productivity in areas where it is endemic. Entire villages have relocated away from the fertile lands near rivers where black flies breed."}, {"prompt": "What makes Onchocerciasis a priority in global health efforts? related to Yellow Fever Disease", "completion": "Nearly the entire world's estimated 18 million infected persons (of whom more than 250,000 are blind) live within 26 African countries. Onchocerciasis is the second leading infectious cause of blindness worldwide. It causes debilitating skin problems, leading to significant decreases in productivity in areas where it is endemic. Entire villages have relocated away from the fertile lands near rivers where black flies breed."}, {"prompt": "What are the reasons behind Onchocerciasis being a global health priority? related to Yellow Fever Disease", "completion": "Nearly the entire world's estimated 18 million infected persons (of whom more than 250,000 are blind) live within 26 African countries. Onchocerciasis is the second leading infectious cause of blindness worldwide. It causes debilitating skin problems, leading to significant decreases in productivity in areas where it is endemic. Entire villages have relocated away from the fertile lands near rivers where black flies breed."}, {"prompt": "Who is most vulnerable to Onchocerciasis? related to Yellow Fever Disease", "completion": "In an endemic area, any person with fibrous nodules in subcutaneous tissues."}, {"prompt": "Who are the individuals most susceptible to Onchocerciasis? related to Yellow Fever Disease", "completion": "In an endemic area, any person with fibrous nodules in subcutaneous tissues."}, {"prompt": "What groups of people are at the highest risk of Onchocerciasis? related to Yellow Fever Disease", "completion": "In an endemic area, any person with fibrous nodules in subcutaneous tissues."}, {"prompt": "What are the surveillance objectives for Onchocerciasis? related to Yellow Fever Disease", "completion": "Early detection with goal of reducing the recurrence of transmission of the parasite in areas where it has been eradicated (zones covered by the Onchocerciasis Program). Conduct periodic surveillance in sentinel villages: screen using diethylcarbamzaine (DEC); in case of a positive reaction to DEC, confirm with a microscopic examination of a skin biopsy from each suspected case."}, {"prompt": "What are the goals of Onchocerciasis surveillance? related to Yellow Fever Disease", "completion": "Early detection with goal of reducing the recurrence of transmission of the parasite in areas where it has been eradicated (zones covered by the Onchocerciasis Program). Conduct periodic surveillance in sentinel villages: screen using diethylcarbamzaine (DEC); in case of a positive reaction to DEC, confirm with a microscopic examination of a skin biopsy from each suspected case."}, {"prompt": "What are the surveillance targets for Onchocerciasis? related to Yellow Fever Disease", "completion": "Early detection with goal of reducing the recurrence of transmission of the parasite in areas where it has been eradicated (zones covered by the Onchocerciasis Program). Conduct periodic surveillance in sentinel villages: screen using diethylcarbamzaine (DEC); in case of a positive reaction to DEC, confirm with a microscopic examination of a skin biopsy from each suspected case."}, {"prompt": "What is the standard case definition for a suspected new case of Onchocerciasis? related to Yellow Fever Disease", "completion": "In an endemic area, any person with fibrous nodules in subcutaneous tissues."}, {"prompt": "When should a person be suspected to have Onchocerciasis? related to Yellow Fever Disease", "completion": "In an endemic area, any person with fibrous nodules in subcutaneous tissues."}, {"prompt": "What is the case definition for suspecting a new case of Onchocerciasis? related to Yellow Fever Disease", "completion": "In an endemic area, any person with fibrous nodules in subcutaneous tissues."}, {"prompt": "What is the standard case definition for a confirmed case of Onchocerciasis? related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed by presence of one or more of the following: microfilariae in skin snips, adult worms in excised nodules, or typical ocular manifestations (such as slit-lamp observations of microfilariae in the cornea, the anterior chamber, or the vitreous body)."}, {"prompt": "How is a confirmed case of Onchocerciasis defined? related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed by presence of one or more of the following: microfilariae in skin snips, adult worms in excised nodules, or typical ocular manifestations (such as slit-lamp observations of microfilariae in the cornea, the anterior chamber, or the vitreous body)."}, {"prompt": "What are the criteria for confirming a case of Onchocerciasis? related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed by presence of one or more of the following: microfilariae in skin snips, adult worms in excised nodules, or typical ocular manifestations (such as slit-lamp observations of microfilariae in the cornea, the anterior chamber, or the vitreous body)."}, {"prompt": "When should an alert be raised for Onchocerciasis? related to Yellow Fever Disease", "completion": "If a suspected case is detected: Report the case according to national guidelines. Collect specimen for confirming the case. Investigate the case to determine the cause of the case. Treat the case according to national guidelines."}, {"prompt": "Under what circumstances should an alert be raised for Onchocerciasis? related to Yellow Fever Disease", "completion": "If a suspected case is detected: Report the case according to national guidelines. Collect specimen for confirming the case. Investigate the case to determine the cause of the case. Treat the case according to national guidelines."}, {"prompt": "What actions should be taken if a single case of Onchocerciasis is confirmed? related to Yellow Fever Disease", "completion": "If a case is confirmed: Conduct a migration investigation to identify the origins of infection and initiate control activities. Carry out vector control activities according to OCP guidelines. Conduct periodic mass treatment with ivermectin in areas with endemic onchocerciasis during the last 10 years. Conduct active case finding via population-based surveys and skin snips."}, {"prompt": "What measures are recommended when a single case of Onchocerciasis is confirmed? related to Yellow Fever Disease", "completion": "If a case is confirmed: Conduct a migration investigation to identify the origins of infection and initiate control activities. Carry out vector control activities according to OCP guidelines. Conduct periodic mass treatment with ivermectin in areas with endemic onchocerciasis during the last 10 years. Conduct active case finding via population-based surveys and skin snips."}, {"prompt": "How should data about a person with Onchocerciasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count quarterly cases and analyze age distribution."}, {"prompt": "What are the methods used to analyze data about individuals with Onchocerciasis? related to Yellow Fever Disease", "completion": "Count quarterly cases and analyze age distribution."}, {"prompt": "How can we interpret the data on Onchocerciasis cases and individuals? related to Yellow Fever Disease", "completion": "Count quarterly cases and analyze age distribution."}, {"prompt": "How should data about time in the context of Onchocerciasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases quarterly."}, {"prompt": "What are the techniques used for temporal analysis of Onchocerciasis cases? related to Yellow Fever Disease", "completion": "Graph cases quarterly."}, {"prompt": "How can temporal analysis help in understanding Onchocerciasis trends? related to Yellow Fever Disease", "completion": "Graph cases quarterly."}, {"prompt": "How should data about place in the context of Onchocerciasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot distribution of patients' household and workplaces."}, {"prompt": "What are the methods used for spatial analysis of Onchocerciasis cases? related to Yellow Fever Disease", "completion": "Plot distribution of patients' household and workplaces."}, {"prompt": "How can spatial analysis contribute to understanding Onchocerciasis transmission? related to Yellow Fever Disease", "completion": "Plot distribution of patients' household and workplaces."}, {"prompt": "What are the laboratory procedures for diagnosing Onchocerciasis? related to Yellow Fever Disease", "completion": "Microscopy. Laboratory criteria for confirmation: One or more of the following: presence of microfilariae in skin snips taken from the iliac crest. presence of adult worms in excised nodules. presence of typical ocular manifestations, such as slit-lamp observations of microfilariae in the cornea, the anterior chamber, or the vitreous body. Specimens include: Skin snips from: Nodule fluids, Iliac crests, Scapula area. Specimens should be taken 1 hour after administration of Diethyl carbomazine and prepared by putting the sample in a general container, adding a few drops of normal saline, and tightly sealing it. It should be transported at ambient temperature and results should be ready within 1 day."}, {"prompt": "How is Onchocerciasis diagnosed using laboratory techniques? related to Yellow Fever Disease", "completion": "Microscopy. Laboratory criteria for confirmation: One or more of the following: presence of microfilariae in skin snips taken from the iliac crest. presence of adult worms in excised nodules. presence of typical ocular manifestations, such as slit-lamp observations of microfilariae in the cornea, the anterior chamber, or the vitreous body. Specimens include: Skin snips from: Nodule fluids, Iliac crests, Scapula area. Specimens should be taken 1 hour after administration of Diethyl carbomazine and prepared by putting the sample in a general container, adding a few drops of normal saline, and tightly sealing it. It should be transported at ambient temperature and results should be ready within 1 day."}, {"prompt": "What are the references for Onchocerciasis? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards. Second edition. WHO/CDS/CSR/ISR/99.2\n2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2"}, {"prompt": "Where can I find more information about Onchocerciasis? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards. Second edition. WHO/CDS/CSR/ISR/99.2\n2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2"}, {"prompt": "Define Noma. related to Yellow Fever Disease", "completion": "Noma (cancrum oris, stomatitis gangrenosa) is an opportunistic bacterial infection affecting children 1-4 years characterized by quickly spreading orofacial gangrene, evolving from a gingival inflammation. Noma results from complex interactions between risk factors such as poor sanitation, malnutrition, recurrent illnesses, and compromised immunity. Diseases that commonly precede noma include measles, malaria, severe diarrhea, and necrotizing ulcerative gingivitis. Early detection and treatment with antibiotics is key to preventing severe disfigurement or death. In the acute stage, death can be prevented with high doses of penicillin; however disfigurement can only be treated with costly surgery. Prevention should focus on education and awareness of the disease, improved nutrition and household hygiene, promotion of exclusive breastfeeding in the first 3-6 months of life, access to prenatal care, and immunizations against common childhood diseases. Clinical features include soreness of the mouth, pronounced halitosis (bad smelling breath), fetid taste, tenderness of the lip or cheek, cervical lymphadenopathy, a foul-smelling purulent oral discharge, and a blue-black discoloration of the skin and swelling in the affected area."}, {"prompt": "Explain Noma. related to Yellow Fever Disease", "completion": "Noma (cancrum oris, stomatitis gangrenosa) is an opportunistic bacterial infection affecting children 1-4 years characterized by quickly spreading orofacial gangrene, evolving from a gingival inflammation. Noma results from complex interactions between risk factors such as poor sanitation, malnutrition, recurrent illnesses, and compromised immunity. Diseases that commonly precede noma include measles, malaria, severe diarrhea, and necrotizing ulcerative gingivitis. Early detection and treatment with antibiotics is key to preventing severe disfigurement or death. In the acute stage, death can be prevented with high doses of penicillin; however disfigurement can only be treated with costly surgery. Prevention should focus on education and awareness of the disease, improved nutrition and household hygiene, promotion of exclusive breastfeeding in the first 3-6 months of life, access to prenatal care, and immunizations against common childhood diseases. Clinical features include soreness of the mouth, pronounced halitosis (bad smelling breath), fetid taste, tenderness of the lip or cheek, cervical lymphadenopathy, a foul-smelling purulent oral discharge, and a blue-black discoloration of the skin and swelling in the affected area."}, {"prompt": "Elaborate on Noma. related to Yellow Fever Disease", "completion": "Noma (cancrum oris, stomatitis gangrenosa) is an opportunistic bacterial infection affecting children 1-4 years characterized by quickly spreading orofacial gangrene, evolving from a gingival inflammation. Noma results from complex interactions between risk factors such as poor sanitation, malnutrition, recurrent illnesses, and compromised immunity. Diseases that commonly precede noma include measles, malaria, severe diarrhea, and necrotizing ulcerative gingivitis. Early detection and treatment with antibiotics is key to preventing severe disfigurement or death. In the acute stage, death can be prevented with high doses of penicillin; however disfigurement can only be treated with costly surgery. Prevention should focus on education and awareness of the disease, improved nutrition and household hygiene, promotion of exclusive breastfeeding in the first 3-6 months of life, access to prenatal care, and immunizations against common childhood diseases. Clinical features include soreness of the mouth, pronounced halitosis (bad smelling breath), fetid taste, tenderness of the lip or cheek, cervical lymphadenopathy, a foul-smelling purulent oral discharge, and a blue-black discoloration of the skin and swelling in the affected area."}, {"prompt": "Describe Noma. related to Yellow Fever Disease", "completion": "Noma (cancrum oris, stomatitis gangrenosa) is an opportunistic bacterial infection affecting children 1-4 years characterized by quickly spreading orofacial gangrene, evolving from a gingival inflammation. Noma results from complex interactions between risk factors such as poor sanitation, malnutrition, recurrent illnesses, and compromised immunity. Diseases that commonly precede noma include measles, malaria, severe diarrhea, and necrotizing ulcerative gingivitis. Early detection and treatment with antibiotics is key to preventing severe disfigurement or death. In the acute stage, death can be prevented with high doses of penicillin; however disfigurement can only be treated with costly surgery. Prevention should focus on education and awareness of the disease, improved nutrition and household hygiene, promotion of exclusive breastfeeding in the first 3-6 months of life, access to prenatal care, and immunizations against common childhood diseases. Clinical features include soreness of the mouth, pronounced halitosis (bad smelling breath), fetid taste, tenderness of the lip or cheek, cervical lymphadenopathy, a foul-smelling purulent oral discharge, and a blue-black discoloration of the skin and swelling in the affected area."}, {"prompt": "What is the nature of Noma? related to Yellow Fever Disease", "completion": "Noma (cancrum oris, stomatitis gangrenosa) is an opportunistic bacterial infection affecting children 1-4 years characterized by quickly spreading orofacial gangrene, evolving from a gingival inflammation. Noma results from complex interactions between risk factors such as poor sanitation, malnutrition, recurrent illnesses, and compromised immunity. Diseases that commonly precede noma include measles, malaria, severe diarrhea, and necrotizing ulcerative gingivitis. Early detection and treatment with antibiotics is key to preventing severe disfigurement or death. In the acute stage, death can be prevented with high doses of penicillin; however disfigurement can only be treated with costly surgery. Prevention should focus on education and awareness of the disease, improved nutrition and household hygiene, promotion of exclusive breastfeeding in the first 3-6 months of life, access to prenatal care, and immunizations against common childhood diseases. Clinical features include soreness of the mouth, pronounced halitosis (bad smelling breath), fetid taste, tenderness of the lip or cheek, cervical lymphadenopathy, a foul-smelling purulent oral discharge, and a blue-black discoloration of the skin and swelling in the affected area."}, {"prompt": "Why is Noma a global health priority? related to Yellow Fever Disease", "completion": "Noma occurs worldwide, but is most common in sub-Saharan Africa. In 1998, WHO estimated that worldwide 140 000 children contract noma each year, and 79% of them die from the disease and associated complications. In Africa the highest prevalence of Noma occurs in countries bordering the Sahara desert, where a recent report estimates an annual incidence of 25,000. However, Noma can occur wherever there is extreme poverty."}, {"prompt": "What makes Noma a priority in global health efforts? related to Yellow Fever Disease", "completion": "Noma occurs worldwide, but is most common in sub-Saharan Africa. In 1998, WHO estimated that worldwide 140 000 children contract noma each year, and 79% of them die from the disease and associated complications. In Africa the highest prevalence of Noma occurs in countries bordering the Sahara desert, where a recent report estimates an annual incidence of 25,000. However, Noma can occur wherever there is extreme poverty."}, {"prompt": "Why is Noma considered a major health concern? related to Yellow Fever Disease", "completion": "Noma occurs worldwide, but is most common in sub-Saharan Africa. In 1998, WHO estimated that worldwide 140 000 children contract noma each year, and 79% of them die from the disease and associated complications. In Africa the highest prevalence of Noma occurs in countries bordering the Sahara desert, where a recent report estimates an annual incidence of 25,000. However, Noma can occur wherever there is extreme poverty."}, {"prompt": "What are the reasons behind considering Noma a global health priority? related to Yellow Fever Disease", "completion": "Noma occurs worldwide, but is most common in sub-Saharan Africa. In 1998, WHO estimated that worldwide 140 000 children contract noma each year, and 79% of them die from the disease and associated complications. In Africa the highest prevalence of Noma occurs in countries bordering the Sahara desert, where a recent report estimates an annual incidence of 25,000. However, Noma can occur wherever there is extreme poverty."}, {"prompt": "Who is at the highest risk of contracting Noma? related to Yellow Fever Disease", "completion": "Noma occurs worldwide, but is most common in sub-Saharan Africa. In 1998, WHO estimated that worldwide 140 000 children contract noma each year, and 79% of them die from the disease and associated complications. In Africa the highest prevalence of Noma occurs in countries bordering the Sahara desert, where a recent report estimates an annual incidence of 25,000. However, Noma can occur wherever there is extreme poverty."}, {"prompt": "What groups are most vulnerable to Noma? related to Yellow Fever Disease", "completion": "Noma occurs worldwide, but is most common in sub-Saharan Africa. In 1998, WHO estimated that worldwide 140 000 children contract noma each year, and 79% of them die from the disease and associated complications. In Africa the highest prevalence of Noma occurs in countries bordering the Sahara desert, where a recent report estimates an annual incidence of 25,000. However, Noma can occur wherever there is extreme poverty."}, {"prompt": "Who are the most affected by Noma? related to Yellow Fever Disease", "completion": "Noma occurs worldwide, but is most common in sub-Saharan Africa. In 1998, WHO estimated that worldwide 140 000 children contract noma each year, and 79% of them die from the disease and associated complications. In Africa the highest prevalence of Noma occurs in countries bordering the Sahara desert, where a recent report estimates an annual incidence of 25,000. However, Noma can occur wherever there is extreme poverty."}, {"prompt": "What are the main objectives of Noma surveillance? related to Yellow Fever Disease", "completion": "Early detection and treatment of cases. Identification of high risk communities and families. Estimation of disease incidence and identification of risk factors"}, {"prompt": "What are the goals of Noma surveillance? related to Yellow Fever Disease", "completion": "Early detection and treatment of cases. Identification of high risk communities and families. Estimation of disease incidence and identification of risk factors"}, {"prompt": "What is the purpose of Noma surveillance? related to Yellow Fever Disease", "completion": "Early detection and treatment of cases. Identification of high risk communities and families. Estimation of disease incidence and identification of risk factors"}, {"prompt": "What defines a suspected new case of Noma? related to Yellow Fever Disease", "completion": "Any child with a mouth ulcer and other warning signs such as; malnutrition, poor hygiene, recent illness from; measles, persistent diarrhoea, or malaria should be regarded as a potential noma case"}, {"prompt": "How can a suspected new case of Noma be identified? related to Yellow Fever Disease", "completion": "Any child with a mouth ulcer and other warning signs such as; malnutrition, poor hygiene, recent illness from; measles, persistent diarrhoea, or malaria should be regarded as a potential noma case"}, {"prompt": "What are the criteria for suspecting a new case of Noma? related to Yellow Fever Disease", "completion": "Any child with a mouth ulcer and other warning signs such as; malnutrition, poor hygiene, recent illness from; measles, persistent diarrhoea, or malaria should be regarded as a potential noma case"}, {"prompt": "What constitutes a confirmed case of Noma? related to Yellow Fever Disease", "completion": "Any person with a gangrenous disease which starts as gingival ulceration and spreads rapidly through the tissues of the mouth and face, destroying the soft and hard tissues."}, {"prompt": "How is a confirmed case of Noma defined? related to Yellow Fever Disease", "completion": "Any person with a gangrenous disease which starts as gingival ulceration and spreads rapidly through the tissues of the mouth and face, destroying the soft and hard tissues."}, {"prompt": "What is the standard definition of a confirmed Noma case? related to Yellow Fever Disease", "completion": "Any person with a gangrenous disease which starts as gingival ulceration and spreads rapidly through the tissues of the mouth and face, destroying the soft and hard tissues."}, {"prompt": "What public health actions are recommended for Noma? related to Yellow Fever Disease", "completion": "When a suspected case is detected: Treat the case with nationally recommended antibiotic. Conduct health promotion activities in the community for: Awareness of Noma among the community and in the household. Improved environmental sanitation and personal hygiene. Separation of livestock from areas where humans live. Exclusive breast feeding for the first 6 months of life. Improved nutrition and food preparation techniques. Increase vaccination coverage in the district. Improve sources of drinking water in at-risk communities. Train public health personnel on early recognition of oral lesions that can lead to Noma."}, {"prompt": "What measures should be taken when a suspected case of Noma is detected? related to Yellow Fever Disease", "completion": "When a suspected case is detected: Treat the case with nationally recommended antibiotic. Conduct health promotion activities in the community for: Awareness of Noma among the community and in the household. Improved environmental sanitation and personal hygiene. Separation of livestock from areas where humans live. Exclusive breast feeding for the first 6 months of life. Improved nutrition and food preparation techniques. Increase vaccination coverage in the district. Improve sources of drinking water in at-risk communities. Train public health personnel on early recognition of oral lesions that can lead to Noma."}, {"prompt": "What actions should be taken when a suspected case of Noma is identified? related to Yellow Fever Disease", "completion": "When a suspected case is detected: Treat the case with nationally recommended antibiotic. Conduct health promotion activities in the community for: Awareness of Noma among the community and in the household. Improved environmental sanitation and personal hygiene. Separation of livestock from areas where humans live. Exclusive breast feeding for the first 6 months of life. Improved nutrition and food preparation techniques. Increase vaccination coverage in the district. Improve sources of drinking water in at-risk communities. Train public health personnel on early recognition of oral lesions that can lead to Noma."}, {"prompt": "How should data about a person with Noma be analyzed? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "What methods can be used to analyze data about a person with Noma? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "What factors should be considered when analyzing data about a person with Noma? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "How is time-related data about Noma analyzed? related to Yellow Fever Disease", "completion": "Monitor number of cases detected in time for treatment and use of standardized treatment. Monitor cases over time to estimate burden of disease and identify trends."}, {"prompt": "What analysis can be done with time-related data about Noma? related to Yellow Fever Disease", "completion": "Monitor number of cases detected in time for treatment and use of standardized treatment. Monitor cases over time to estimate burden of disease and identify trends."}, {"prompt": "How can time-related data about Noma be interpreted? related to Yellow Fever Disease", "completion": "Monitor number of cases detected in time for treatment and use of standardized treatment. Monitor cases over time to estimate burden of disease and identify trends."}, {"prompt": "What methods are used to analyze data related to the time aspect of Noma? related to Yellow Fever Disease", "completion": "Monitor number of cases detected in time for treatment and use of standardized treatment. Monitor cases over time to estimate burden of disease and identify trends."}, {"prompt": "What is the analysis approach for data about the place aspect of Noma? related to Yellow Fever Disease", "completion": "Plot the location of case households and analyze the distribution."}, {"prompt": "How can data about the place aspect of Noma be interpreted? related to Yellow Fever Disease", "completion": "Plot the location of case households and analyze the distribution."}, {"prompt": "What are the recommended methods for analyzing data about the place aspect of Noma? related to Yellow Fever Disease", "completion": "Plot the location of case households and analyze the distribution."}, {"prompt": "How is Noma diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "What laboratory tests are used for diagnosing Noma? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "Are laboratory tests routinely used to diagnose Noma? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required."}, {"prompt": "What are the references for Noma? related to Yellow Fever Disease", "completion": "1. Enwonwu, C. (2006). \"Noma--the ulcer of extreme poverty.\" New England Journal of Medicine, The 354(3): 221-224\n2. Enwonwu, C., W. Falkler, et al. (2006). \"Noma (cancrum oris).\" The Lancet 368(9530): 147- 156.\n3. Fieger, A., K. Marck, et al. (2003). \"An estimation of the incidence of noma in north-west Nigeria.\" Tropical medicine & international health 8(5): 402-407.\n4. Enwonwu, C. O. (1995). \"Noma: a neglected scourge of children in sub-Saharan Africa.\" Bulletin of the World Health Organization 73(4): 541-545.\n5. Enwonwu, C. O., W. A. Falkler, et al. (1999). \"Pathogenesis of cancrum oris (noma): confounding interactions of malnutrition with infection.\" The American journal of tropical medicine and hygiene 60(2): 223-232."}, {"prompt": "Where can I find more information about Noma? related to Yellow Fever Disease", "completion": "1. Enwonwu, C. (2006). \"Noma--the ulcer of extreme poverty.\" New England Journal of Medicine, The 354(3): 221-224\n2. Enwonwu, C., W. Falkler, et al. (2006). \"Noma (cancrum oris).\" The Lancet 368(9530): 147- 156.\n3. Fieger, A., K. Marck, et al. (2003). \"An estimation of the incidence of noma in north-west Nigeria.\" Tropical medicine & international health 8(5): 402-407.\n4. Enwonwu, C. O. (1995). \"Noma: a neglected scourge of children in sub-Saharan Africa.\" Bulletin of the World Health Organization 73(4): 541-545.\n5. Enwonwu, C. O., W. A. Falkler, et al. (1999). \"Pathogenesis of cancrum oris (noma): confounding interactions of malnutrition with infection.\" The American journal of tropical medicine and hygiene 60(2): 223-232."}, {"prompt": "What publications can provide more information on Noma? related to Yellow Fever Disease", "completion": "1. Enwonwu, C. (2006). \"Noma--the ulcer of extreme poverty.\" New England Journal of Medicine, The 354(3): 221-224\n2. Enwonwu, C., W. Falkler, et al. (2006). \"Noma (cancrum oris).\" The Lancet 368(9530): 147- 156.\n3. Fieger, A., K. Marck, et al. (2003). \"An estimation of the incidence of noma in north-west Nigeria.\" Tropical medicine & international health 8(5): 402-407.\n4. Enwonwu, C. O. (1995). \"Noma: a neglected scourge of children in sub-Saharan Africa.\" Bulletin of the World Health Organization 73(4): 541-545.\n5. Enwonwu, C. O., W. A. Falkler, et al. (1999). \"Pathogenesis of cancrum oris (noma): confounding interactions of malnutrition with infection.\" The American journal of tropical medicine and hygiene 60(2): 223-232."}, {"prompt": "Where can I access scientific literature on Noma? related to Yellow Fever Disease", "completion": "1. Enwonwu, C. (2006). \"Noma--the ulcer of extreme poverty.\" New England Journal of Medicine, The 354(3): 221-224\n2. Enwonwu, C., W. Falkler, et al. (2006). \"Noma (cancrum oris).\" The Lancet 368(9530): 147- 156.\n3. Fieger, A., K. Marck, et al. (2003). \"An estimation of the incidence of noma in north-west Nigeria.\" Tropical medicine & international health 8(5): 402-407.\n4. Enwonwu, C. O. (1995). \"Noma: a neglected scourge of children in sub-Saharan Africa.\" Bulletin of the World Health Organization 73(4): 541-545.\n5. Enwonwu, C. O., W. A. Falkler, et al. (1999). \"Pathogenesis of cancrum oris (noma): confounding interactions of malnutrition with infection.\" The American journal of tropical medicine and hygiene 60(2): 223-232."}, {"prompt": "Define AIDS and its causes. related to Yellow Fever Disease", "completion": "AIDS is an infection of human lymphocytes (types of white blood cells) and other organs. It is caused by a retrovirus, human immunodeficiency virus (HIV). Sexual intercourse, needle injections, transfusions, trans-placental or trans-vaginal routes, breast milk or other direct contact with infected human body fluids transmits the virus from human to human. Acquired immunodeficiency syndrome (AIDS) results in late-stage HIV infection and immuno-suppression, with reduced numbers and function to T-lymphocytes. Primary HIV- related organ involvement and a variety of opportunistic infections result in death unless the growth of the virus is stopped by drugs that can kill the virus (antiretroviral therapy). When HIV infection progresses to illness, the symptoms are usually due to the failure of the immune system to resist other infectious diseases called opportunistic infections (OI). These include tuberculosis, bacterial pneumonia or sepsis, oro-pharyngeal candidiasis, chronic diarrhoea, chronic skin infections, recurrent herpes zoster, and others. Incubation period is approximately 1 to 3 months from the time of infection to the time that antibodies can be detected in a laboratory process. The time from HIV infection to the onset of AIDS is generally 7 to 9 years."}, {"prompt": "What is the nature of New AIDS Cases? related to Yellow Fever Disease", "completion": "AIDS is an infection of human lymphocytes (types of white blood cells) and other organs. It is caused by a retrovirus, human immunodeficiency virus (HIV). Sexual intercourse, needle injections, transfusions, trans-placental or trans-vaginal routes, breast milk or other direct contact with infected human body fluids transmits the virus from human to human. Acquired immunodeficiency syndrome (AIDS) results in late-stage HIV infection and immuno-suppression, with reduced numbers and function to T-lymphocytes. Primary HIV- related organ involvement and a variety of opportunistic infections result in death unless the growth of the virus is stopped by drugs that can kill the virus (antiretroviral therapy). When HIV infection progresses to illness, the symptoms are usually due to the failure of the immune system to resist other infectious diseases called opportunistic infections (OI). These include tuberculosis, bacterial pneumonia or sepsis, oro-pharyngeal candidiasis, chronic diarrhoea, chronic skin infections, recurrent herpes zoster, and others. Incubation period is approximately 1 to 3 months from the time of infection to the time that antibodies can be detected in a laboratory process. The time from HIV infection to the onset of AIDS is generally 7 to 9 years."}, {"prompt": "Explain AIDS and its transmission. related to Yellow Fever Disease", "completion": "AIDS is an infection of human lymphocytes (types of white blood cells) and other organs. It is caused by a retrovirus, human immunodeficiency virus (HIV). Sexual intercourse, needle injections, transfusions, trans-placental or trans-vaginal routes, breast milk or other direct contact with infected human body fluids transmits the virus from human to human. Acquired immunodeficiency syndrome (AIDS) results in late-stage HIV infection and immuno-suppression, with reduced numbers and function to T-lymphocytes. Primary HIV- related organ involvement and a variety of opportunistic infections result in death unless the growth of the virus is stopped by drugs that can kill the virus (antiretroviral therapy). When HIV infection progresses to illness, the symptoms are usually due to the failure of the immune system to resist other infectious diseases called opportunistic infections (OI). These include tuberculosis, bacterial pneumonia or sepsis, oro-pharyngeal candidiasis, chronic diarrhoea, chronic skin infections, recurrent herpes zoster, and others. Incubation period is approximately 1 to 3 months from the time of infection to the time that antibodies can be detected in a laboratory process. The time from HIV infection to the onset of AIDS is generally 7 to 9 years."}, {"prompt": "Describe New AIDS Cases and its transmission. related to Yellow Fever Disease", "completion": "AIDS is an infection of human lymphocytes (types of white blood cells) and other organs. It is caused by a retrovirus, human immunodeficiency virus (HIV). Sexual intercourse, needle injections, transfusions, trans-placental or trans-vaginal routes, breast milk or other direct contact with infected human body fluids transmits the virus from human to human. Acquired immunodeficiency syndrome (AIDS) results in late-stage HIV infection and immuno-suppression, with reduced numbers and function to T-lymphocytes. Primary HIV- related organ involvement and a variety of opportunistic infections result in death unless the growth of the virus is stopped by drugs that can kill the virus (antiretroviral therapy). When HIV infection progresses to illness, the symptoms are usually due to the failure of the immune system to resist other infectious diseases called opportunistic infections (OI). These include tuberculosis, bacterial pneumonia or sepsis, oro-pharyngeal candidiasis, chronic diarrhoea, chronic skin infections, recurrent herpes zoster, and others. Incubation period is approximately 1 to 3 months from the time of infection to the time that antibodies can be detected in a laboratory process. The time from HIV infection to the onset of AIDS is generally 7 to 9 years."}, {"prompt": "What are the priority areas for New AIDS Cases? related to Yellow Fever Disease", "completion": "Twenty-four million Africans, close to one in ten adults between the ages of 15 and 49 years of age, are living with HIV/AIDS. The impact of the epidemic is already measurable in greatly increased adult and child morbidity and mortality. HIV/AIDS is now the leading cause of adult mortality in the African Region."}, {"prompt": "Why is New AIDS Cases a critical issue in Africa? related to Yellow Fever Disease", "completion": "Twenty-four million Africans, close to one in ten adults between the ages of 15 and 49 years of age, are living with HIV/AIDS. The impact of the epidemic is already measurable in greatly increased adult and child morbidity and mortality. HIV/AIDS is now the leading cause of adult mortality in the African Region."}, {"prompt": "What are the main concerns regarding New AIDS Cases in Africa? related to Yellow Fever Disease", "completion": "Twenty-four million Africans, close to one in ten adults between the ages of 15 and 49 years of age, are living with HIV/AIDS. The impact of the epidemic is already measurable in greatly increased adult and child morbidity and mortality. HIV/AIDS is now the leading cause of adult mortality in the African Region."}, {"prompt": "What are the surveillance objectives for New AIDS Cases? related to Yellow Fever Disease", "completion": "Monitor the impact of HIV/AIDS interventions in trends of incidence and prevalence of HIV infections, AIDS and STIs through sentinel sites, surveys and special studies (according to guidelines for second generation surveillance of HIV/AIDS). Estimate the burden of HIV/AIDS in the district using available information from HIV sentinel populations so that each new AIDS case is counted. Monitor local STI epidemiology as possible cofactor for HIV transmission. Monitor local opportunistic infection epidemiology, including TB. Improve percentage of suspected HIV/AIDS cases confirmed via serology. Improve HIV/AIDS screening."}, {"prompt": "What is the purpose of New AIDS Cases surveillance? related to Yellow Fever Disease", "completion": "Monitor the impact of HIV/AIDS interventions in trends of incidence and prevalence of HIV infections, AIDS and STIs through sentinel sites, surveys and special studies (according to guidelines for second generation surveillance of HIV/AIDS). Estimate the burden of HIV/AIDS in the district using available information from HIV sentinel populations so that each new AIDS case is counted. Monitor local STI epidemiology as possible cofactor for HIV transmission. Monitor local opportunistic infection epidemiology, including TB. Improve percentage of suspected HIV/AIDS cases confirmed via serology. Improve HIV/AIDS screening."}, {"prompt": "What is the standard case definition for New AIDS Cases? related to Yellow Fever Disease", "completion": "WHO/AFRO recommends that countries use either Bangui or Abidjan HIV/AIDSR case definitions. A positive ELISA for confirming HIV and a rapid test for confirming the positive results are sufficient for an epidemiologic case definition for HIV infection."}, {"prompt": "What criteria are used to define a confirmed new case of New AIDS Cases? related to Yellow Fever Disease", "completion": "WHO/AFRO recommends that countries use either Bangui or Abidjan HIV/AIDSR case definitions. A positive ELISA for confirming HIV and a rapid test for confirming the positive results are sufficient for an epidemiologic case definition for HIV infection."}, {"prompt": "How are confirmed new cases of New AIDS Cases identified? related to Yellow Fever Disease", "completion": "WHO/AFRO recommends that countries use either Bangui or Abidjan HIV/AIDSR case definitions. A positive ELISA for confirming HIV and a rapid test for confirming the positive results are sufficient for an epidemiologic case definition for HIV infection."}, {"prompt": "What are the recommended public health measures for New AIDS Cases? related to Yellow Fever Disease", "completion": "Monitor local STI and opportunistic infections, including TB, as possible cofactor for HIV. Improve percentage of suspected HIV/AIDS cases confirmed via serology. Monitor use of condoms by commercial sex workers. Provide voluntary counselling and testing services at district and sub-district levels. Treatment of individual cases with antiretroviral therapy is not yet widely available in most African countries. Rapid diagnosis and treatment of AIDS-related opportunistic infection (OI) may prolong life expectancy but this has not been widely evaluated in developing countries. Promote condom use, especially among high-risk individuals. Treat STIs, especially syphilis, chancroid diseases, and other ulcerative processes. Mobilize non-paid blood donors and promote appropriate use of blood. Promote good infection control practices within health facilities in the district. Educate patients and their sexual partners to refrain from donating blood, tissues, semen or breast milk."}, {"prompt": "What actions can be taken to address New AIDS Cases? related to Yellow Fever Disease", "completion": "Monitor local STI and opportunistic infections, including TB, as possible cofactor for HIV. Improve percentage of suspected HIV/AIDS cases confirmed via serology. Monitor use of condoms by commercial sex workers. Provide voluntary counselling and testing services at district and sub-district levels. Treatment of individual cases with antiretroviral therapy is not yet widely available in most African countries. Rapid diagnosis and treatment of AIDS-related opportunistic infection (OI) may prolong life expectancy but this has not been widely evaluated in developing countries. Promote condom use, especially among high-risk individuals. Treat STIs, especially syphilis, chancroid diseases, and other ulcerative processes. Mobilize non-paid blood donors and promote appropriate use of blood. Promote good infection control practices within health facilities in the district. Educate patients and their sexual partners to refrain from donating blood, tissues, semen or breast milk."}, {"prompt": "How should data about time in the context of New AIDS Cases be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count new AIDS cases and report monthly. Analyze by number of cases confirmed with serology. At the end of the year, calculate the total number of cases and include trends for HIV sero-surveillance, STI surveillance and results of any special studies (socio- behavioural studies, drug sensitivity to antimicrobial agents, and so on)."}, {"prompt": "What are the methods for analyzing time-based data on New AIDS Cases? related to Yellow Fever Disease", "completion": "Count new AIDS cases and report monthly. Analyze by number of cases confirmed with serology. At the end of the year, calculate the total number of cases and include trends for HIV sero-surveillance, STI surveillance and results of any special studies (socio- behavioural studies, drug sensitivity to antimicrobial agents, and so on)."}, {"prompt": "How can temporal analysis assist in understanding New AIDS Cases trends? related to Yellow Fever Disease", "completion": "Count new AIDS cases and report monthly. Analyze by number of cases confirmed with serology. At the end of the year, calculate the total number of cases and include trends for HIV sero-surveillance, STI surveillance and results of any special studies (socio- behavioural studies, drug sensitivity to antimicrobial agents, and so on)."}, {"prompt": "How is New AIDS Cases diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "For adults and children 18 months or older, HIV infection is diagnosed based on: Positive HIV antibody testing (rapid or laboratory- based enzyme immunoassay). This is confirmed by a second HIV antibody test (rapid or laboratory-based enzyme immunoassay) relying on different antigens or of different operating characteristics; AND/OR Positive virological test for HIV or its components (HIV-RNA or HIV-DNA or ultrasensitive HIV p24 antigen) confirmed by a second virological test obtained from a separate determination. For children younger than 18 months, HIV infection is diagnosed based on positive virological test for HIV or its components (HIV-RNA or HIV-DNA or ultrasensitive HIV p24 antigen) confirmed by a second virological test obtained from a separate determination taken more than four weeks after birth. Positive HIV antibody testing is not recommended for definitive or confirmatory diagnosis of HIV infection in children until 18 months of age."}, {"prompt": "How is New AIDS Cases diagnosed using laboratory techniques? related to Yellow Fever Disease", "completion": "For adults and children 18 months or older, HIV infection is diagnosed based on: Positive HIV antibody testing (rapid or laboratory- based enzyme immunoassay). This is confirmed by a second HIV antibody test (rapid or laboratory-based enzyme immunoassay) relying on different antigens or of different operating characteristics; AND/OR Positive virological test for HIV or its components (HIV-RNA or HIV-DNA or ultrasensitive HIV p24 antigen) confirmed by a second virological test obtained from a separate determination. For children younger than 18 months, HIV infection is diagnosed based on positive virological test for HIV or its components (HIV-RNA or HIV-DNA or ultrasensitive HIV p24 antigen) confirmed by a second virological test obtained from a separate determination taken more than four weeks after birth. Positive HIV antibody testing is not recommended for definitive or confirmatory diagnosis of HIV infection in children until 18 months of age."}, {"prompt": "What are the references for New AIDS Cases? related to Yellow Fever Disease", "completion": "1. Guidelines for Sexually Transmitted Infections Surveillance. Geneva. UNAIDS and World Health Organization. WHO/CDS/CSR/EDC/99.3. UNAIDS/99.33E\n2. WHO Case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-Related disease in adults and children.\n3. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n4. Guidelines for Second Generation HIV Surveillance, WHO and UNAIDS, 2000 WHO/CDC/CSR/EDC/2000.5\n5. Consultation on technical and operational recommendations for clinical laboratory testing harmonization and standardization, Jan 2008, WHO, CDC"}, {"prompt": "What sources can be consulted for more information on New AIDS Cases? related to Yellow Fever Disease", "completion": "1. Guidelines for Sexually Transmitted Infections Surveillance. Geneva. UNAIDS and World Health Organization. WHO/CDS/CSR/EDC/99.3. UNAIDS/99.33E\n2. WHO Case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-Related disease in adults and children.\n3. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n4. Guidelines for Second Generation HIV Surveillance, WHO and UNAIDS, 2000 WHO/CDC/CSR/EDC/2000.5\n5. Consultation on technical and operational recommendations for clinical laboratory testing harmonization and standardization, Jan 2008, WHO, CDC"}, {"prompt": "Explain Neonatal tetanus. related to Yellow Fever Disease", "completion": "Neonatal tetanus is a neuromuscular toxin-mediated illness caused by the anaerobic spore-forming soil bacterium Clostridium tetani. The disease is transmitted when spores enter open wounds (like injections, cutting the umbilical cord) or breaks in the skin. Though tetanus can occur in adults, the infection primarily affects newborns. Neonatal tetanus has significantly decreased in countries with improved maternal tetanus immunization rates. As a result, many African countries target tetanus for elimination. The incubation period ranges from 3 to 21 days, averaging approximately 6 days."}, {"prompt": "Describe Neonatal tetanus. related to Yellow Fever Disease", "completion": "Neonatal tetanus is a neuromuscular toxin-mediated illness caused by the anaerobic spore-forming soil bacterium Clostridium tetani. The disease is transmitted when spores enter open wounds (like injections, cutting the umbilical cord) or breaks in the skin. Though tetanus can occur in adults, the infection primarily affects newborns. Neonatal tetanus has significantly decreased in countries with improved maternal tetanus immunization rates. As a result, many African countries target tetanus for elimination. The incubation period ranges from 3 to 21 days, averaging approximately 6 days."}, {"prompt": "Elaborate on Neonatal tetanus. related to Yellow Fever Disease", "completion": "Neonatal tetanus is a neuromuscular toxin-mediated illness caused by the anaerobic spore-forming soil bacterium Clostridium tetani. The disease is transmitted when spores enter open wounds (like injections, cutting the umbilical cord) or breaks in the skin. Though tetanus can occur in adults, the infection primarily affects newborns. Neonatal tetanus has significantly decreased in countries with improved maternal tetanus immunization rates. As a result, many African countries target tetanus for elimination. The incubation period ranges from 3 to 21 days, averaging approximately 6 days."}, {"prompt": "Define Neonatal tetanus. related to Yellow Fever Disease", "completion": "Neonatal tetanus is a neuromuscular toxin-mediated illness caused by the anaerobic spore-forming soil bacterium Clostridium tetani. The disease is transmitted when spores enter open wounds (like injections, cutting the umbilical cord) or breaks in the skin. Though tetanus can occur in adults, the infection primarily affects newborns. Neonatal tetanus has significantly decreased in countries with improved maternal tetanus immunization rates. As a result, many African countries target tetanus for elimination. The incubation period ranges from 3 to 21 days, averaging approximately 6 days."}, {"prompt": "What is the nature of Neonatal tetanus? related to Yellow Fever Disease", "completion": "Neonatal tetanus is a neuromuscular toxin-mediated illness caused by the anaerobic spore-forming soil bacterium Clostridium tetani. The disease is transmitted when spores enter open wounds (like injections, cutting the umbilical cord) or breaks in the skin. Though tetanus can occur in adults, the infection primarily affects newborns. Neonatal tetanus has significantly decreased in countries with improved maternal tetanus immunization rates. As a result, many African countries target tetanus for elimination. The incubation period ranges from 3 to 21 days, averaging approximately 6 days."}, {"prompt": "What are the risk factors for Neonatal tetanus? related to Yellow Fever Disease", "completion": "The primary risk factors include unclean cord care practices during delivery for neonates and a lack of antibody protection in mothers who are not fully immunized."}, {"prompt": "What factors contribute to Neonatal tetanus? related to Yellow Fever Disease", "completion": "The primary risk factors include unclean cord care practices during delivery for neonates and a lack of antibody protection in mothers who are not fully immunized."}, {"prompt": "What are the determinants of Neonatal tetanus? related to Yellow Fever Disease", "completion": "The primary risk factors include unclean cord care practices during delivery for neonates and a lack of antibody protection in mothers who are not fully immunized."}, {"prompt": "What are the surveillance goals for Neonatal tetanus? related to Yellow Fever Disease", "completion": "The main goals are to immediately detect cases of neonatal tetanus to confirm the case and prevent further cases by immunizing, at least, pregnant women in the area surrounding the confirmed case. It's also essential to identify high-risk areas and target tetanus toxoid campaigns towards women of childbearing age."}, {"prompt": "What are the objectives of Neonatal tetanus surveillance? related to Yellow Fever Disease", "completion": "The main goals are to immediately detect cases of neonatal tetanus to confirm the case and prevent further cases by immunizing, at least, pregnant women in the area surrounding the confirmed case. It's also essential to identify high-risk areas and target tetanus toxoid campaigns towards women of childbearing age."}, {"prompt": "What is the purpose of Neonatal tetanus surveillance? related to Yellow Fever Disease", "completion": "The main goals are to immediately detect cases of neonatal tetanus to confirm the case and prevent further cases by immunizing, at least, pregnant women in the area surrounding the confirmed case. It's also essential to identify high-risk areas and target tetanus toxoid campaigns towards women of childbearing age."}, {"prompt": "What is the standard case definition for Neonatal tetanus? related to Yellow Fever Disease", "completion": "Suspected Case: Any newborn with a normal ability to suck and cry during the first two days of life, and who, between the 3rd and 28th day of age, cannot suck normally, and becomes stiff or has convulsions or both. Confirmed Case: No laboratory confirmation is recommended."}, {"prompt": "How is a suspected case of Neonatal tetanus defined? related to Yellow Fever Disease", "completion": "Suspected Case: Any newborn with a normal ability to suck and cry during the first two days of life, and who, between the 3rd and 28th day of age, cannot suck normally, and becomes stiff or has convulsions or both. Confirmed Case: No laboratory confirmation is recommended."}, {"prompt": "What is the case definition for Neonatal tetanus? related to Yellow Fever Disease", "completion": "Suspected Case: Any newborn with a normal ability to suck and cry during the first two days of life, and who, between the 3rd and 28th day of age, cannot suck normally, and becomes stiff or has convulsions or both. Confirmed Case: No laboratory confirmation is recommended."}, {"prompt": "What is the standard case definition for a confirmed case of Neonatal tetanus? related to Yellow Fever Disease", "completion": "Confirmed Case: No laboratory confirmation is recommended."}, {"prompt": "When should an alert be raised for Neonatal tetanus? related to Yellow Fever Disease", "completion": "Immediate actions include reporting case-based information to the next level, conducting an investigation to assess the risk for transmission, and treating and managing the case as per national guidelines, typically with supportive care and, if feasible, in intensive care. Routine isolation precautions are not required."}, {"prompt": "What are the response steps when a single case of Neonatal tetanus is suspected? related to Yellow Fever Disease", "completion": "Immediate actions include reporting case-based information to the next level, conducting an investigation to assess the risk for transmission, and treating and managing the case as per national guidelines, typically with supportive care and, if feasible, in intensive care. Routine isolation precautions are not required."}, {"prompt": "How should you respond to a suspected case of Neonatal tetanus? related to Yellow Fever Disease", "completion": "Immediate actions include reporting case-based information to the next level, conducting an investigation to assess the risk for transmission, and treating and managing the case as per national guidelines, typically with supportive care and, if feasible, in intensive care. Routine isolation precautions are not required."}, {"prompt": "What are the steps to take when a case of Neonatal tetanus is confirmed? related to Yellow Fever Disease", "completion": "Upon confirmation of a case through investigation, it's essential to immunize the mother and other pregnant women in the same area as the case with at least two doses of tetanus toxoid. There should also be a supplemental immunization activity for women of childbearing age in the locality. Efforts should be made to improve routine vaccine coverage through EPI and maternal immunization program activities. Birth attendants and women of childbearing age should be educated on the need for clean cord cutting and care, and the number of trained birth attendants should be increased."}, {"prompt": "How should data about individuals with Neonatal tetanus be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Monthly cases and deaths should be counted, and each case of Neonatal tetanus should be analyzed by cord care practices."}, {"prompt": "What are the methods for analyzing data about individuals with Neonatal tetanus? related to Yellow Fever Disease", "completion": "Monthly cases and deaths should be counted, and each case of Neonatal tetanus should be analyzed by cord care practices."}, {"prompt": "How can we interpret data about individuals with Neonatal tetanus? related to Yellow Fever Disease", "completion": "Monthly cases and deaths should be counted, and each case of Neonatal tetanus should be analyzed by cord care practices."}, {"prompt": "How should data about time in the context of Neonatal tetanus be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed monthly. The target should reflect the elimination target for each district."}, {"prompt": "What are the techniques for analyzing data about time in the context of Neonatal tetanus? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed monthly. The target should reflect the elimination target for each district."}, {"prompt": "How can temporal analysis contribute to understanding Neonatal tetanus trends? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed monthly. The target should reflect the elimination target for each district."}, {"prompt": "How should data about place in the context of Neonatal tetanus be analyzed and interpreted? related to Yellow Fever Disease", "completion": "The location of case households and birth attendants should be plotted."}, {"prompt": "What are the methods for analyzing data about place in the context of Neonatal tetanus? related to Yellow Fever Disease", "completion": "The location of case households and birth attendants should be plotted."}, {"prompt": "How can spatial analysis contribute to understanding Neonatal tetanus transmission? related to Yellow Fever Disease", "completion": "The location of case households and birth attendants should be plotted."}, {"prompt": "How is Neonatal tetanus diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Laboratory confirmation is not required for Neonatal tetanus."}, {"prompt": "What laboratory tests are used to diagnose Neonatal tetanus? related to Yellow Fever Disease", "completion": "Laboratory confirmation is not required for Neonatal tetanus."}, {"prompt": "What is the diagnostic procedure for Neonatal tetanus? related to Yellow Fever Disease", "completion": "Laboratory confirmation is not required for Neonatal tetanus."}, {"prompt": "What are the references for Neonatal tetanus? related to Yellow Fever Disease", "completion": "1. Field guide for training operational level health workers on vaccine preventable disease surveillance, MoH/ UNEPI (Revised edition 2012)\n2. Field manual for neonatal tetanus elimination. Geneva, World Health Organization. WHO/V&B/99.14"}, {"prompt": "Where can I find more information about Neonatal tetanus? related to Yellow Fever Disease", "completion": "1. Field guide for training operational level health workers on vaccine preventable disease surveillance, MoH/ UNEPI (Revised edition 2012)\n2. Field manual for neonatal tetanus elimination. Geneva, World Health Organization. WHO/V&B/99.14"}, {"prompt": "Define Epilepsy. related to Yellow Fever Disease", "completion": "Epilepsy is characterized by the recurrence of at least two epileptic seizures, which manifest as sudden abnormal signs. These signs can be motor, tonic, sensitive, sensorial, neuro-vegetative, or psycho-behavioral. Symptoms may or may not be associated with a loss of consciousness. Epilepsy can develop at any age and is primarily caused by disturbances in brain cells leading to excessive nerve-cell discharges. Depending on the affected cell groups, seizures can be partial or generalized. Convulsions can happen at any age, but not all are epilepsy. In the African Region, epilepsy is common, with a prevalence rate ranging from 2.2 to 58 per 1000. Studies have shown a high incidence in sub-Saharan African countries. Numerous risk factors contribute to its development, and up to 80% of people with epilepsy in developing countries might not receive treatment or even be identified."}, {"prompt": "What are the characteristics of Epilepsy? related to Yellow Fever Disease", "completion": "Epilepsy is characterized by the recurrence of at least two epileptic seizures, which manifest as sudden abnormal signs. These signs can be motor, tonic, sensitive, sensorial, neuro-vegetative, or psycho-behavioral. Symptoms may or may not be associated with a loss of consciousness. Epilepsy can develop at any age and is primarily caused by disturbances in brain cells leading to excessive nerve-cell discharges. Depending on the affected cell groups, seizures can be partial or generalized. Convulsions can happen at any age, but not all are epilepsy. In the African Region, epilepsy is common, with a prevalence rate ranging from 2.2 to 58 per 1000. Studies have shown a high incidence in sub-Saharan African countries. Numerous risk factors contribute to its development, and up to 80% of people with epilepsy in developing countries might not receive treatment or even be identified."}, {"prompt": "Explain Epilepsy. related to Yellow Fever Disease", "completion": "Epilepsy is characterized by the recurrence of at least two epileptic seizures, which manifest as sudden abnormal signs. These signs can be motor, tonic, sensitive, sensorial, neuro-vegetative, or psycho-behavioral. Symptoms may or may not be associated with a loss of consciousness. Epilepsy can develop at any age and is primarily caused by disturbances in brain cells leading to excessive nerve-cell discharges. Depending on the affected cell groups, seizures can be partial or generalized. Convulsions can happen at any age, but not all are epilepsy. In the African Region, epilepsy is common, with a prevalence rate ranging from 2.2 to 58 per 1000. Studies have shown a high incidence in sub-Saharan African countries. Numerous risk factors contribute to its development, and up to 80% of people with epilepsy in developing countries might not receive treatment or even be identified."}, {"prompt": "Describe Epilepsy. related to Yellow Fever Disease", "completion": "Epilepsy is characterized by the recurrence of at least two epileptic seizures, which manifest as sudden abnormal signs. These signs can be motor, tonic, sensitive, sensorial, neuro-vegetative, or psycho-behavioral. Symptoms may or may not be associated with a loss of consciousness. Epilepsy can develop at any age and is primarily caused by disturbances in brain cells leading to excessive nerve-cell discharges. Depending on the affected cell groups, seizures can be partial or generalized. Convulsions can happen at any age, but not all are epilepsy. In the African Region, epilepsy is common, with a prevalence rate ranging from 2.2 to 58 per 1000. Studies have shown a high incidence in sub-Saharan African countries. Numerous risk factors contribute to its development, and up to 80% of people with epilepsy in developing countries might not receive treatment or even be identified."}, {"prompt": "What is the nature of Epilepsy? related to Yellow Fever Disease", "completion": "Epilepsy is characterized by the recurrence of at least two epileptic seizures, which manifest as sudden abnormal signs. These signs can be motor, tonic, sensitive, sensorial, neuro-vegetative, or psycho-behavioral. Symptoms may or may not be associated with a loss of consciousness. Epilepsy can develop at any age and is primarily caused by disturbances in brain cells leading to excessive nerve-cell discharges. Depending on the affected cell groups, seizures can be partial or generalized. Convulsions can happen at any age, but not all are epilepsy. In the African Region, epilepsy is common, with a prevalence rate ranging from 2.2 to 58 per 1000. Studies have shown a high incidence in sub-Saharan African countries. Numerous risk factors contribute to its development, and up to 80% of people with epilepsy in developing countries might not receive treatment or even be identified."}, {"prompt": "Why is Epilepsy a priority health concern? related to Yellow Fever Disease", "completion": "Epilepsy increases mortality risk, especially when detected later due to the shortage of trained health workers to diagnose and treat neurological disorders. Death and injury primarily arise from status epilepticus (especially if medication is abruptly withdrawn), burns, and drowning."}, {"prompt": "What makes Epilepsy a priority in healthcare? related to Yellow Fever Disease", "completion": "Epilepsy increases mortality risk, especially when detected later due to the shortage of trained health workers to diagnose and treat neurological disorders. Death and injury primarily arise from status epilepticus (especially if medication is abruptly withdrawn), burns, and drowning."}, {"prompt": "What are the reasons for Epilepsy being a priority? related to Yellow Fever Disease", "completion": "Epilepsy increases mortality risk, especially when detected later due to the shortage of trained health workers to diagnose and treat neurological disorders. Death and injury primarily arise from status epilepticus (especially if medication is abruptly withdrawn), burns, and drowning."}, {"prompt": "Who is at risk of developing Epilepsy? related to Yellow Fever Disease", "completion": "Several etiological factors are associated with epilepsy. These include communicable diseases (like malaria, tuberculosis, meningitis, neurocysticercosis, and HIV), non-communicable diseases (such as high blood pressure, diabetes, alcoholism, and illicit drug use), as well as poorer medical facilities, general health, and living standards. Cultural beliefs, stigma, and exclusion can also hinder appropriate care and early detection."}, {"prompt": "What are the factors that increase the risk of Epilepsy? related to Yellow Fever Disease", "completion": "Several etiological factors are associated with epilepsy. These include communicable diseases (like malaria, tuberculosis, meningitis, neurocysticercosis, and HIV), non-communicable diseases (such as high blood pressure, diabetes, alcoholism, and illicit drug use), as well as poorer medical facilities, general health, and living standards. Cultural beliefs, stigma, and exclusion can also hinder appropriate care and early detection."}, {"prompt": "What are the risk factors for developing Epilepsy? related to Yellow Fever Disease", "completion": "Several etiological factors are associated with epilepsy. These include communicable diseases (like malaria, tuberculosis, meningitis, neurocysticercosis, and HIV), non-communicable diseases (such as high blood pressure, diabetes, alcoholism, and illicit drug use), as well as poorer medical facilities, general health, and living standards. Cultural beliefs, stigma, and exclusion can also hinder appropriate care and early detection."}, {"prompt": "What are the goals of surveillance for Epilepsy? related to Yellow Fever Disease", "completion": "The goals are to ensure early detection and immediate intervention to reduce the morbidity and mortality rates associated with epilepsy. Additionally, registering and monitoring epilepsy cases is vital."}, {"prompt": "What are the objectives of surveillance for Epilepsy? related to Yellow Fever Disease", "completion": "The goals are to ensure early detection and immediate intervention to reduce the morbidity and mortality rates associated with epilepsy. Additionally, registering and monitoring epilepsy cases is vital."}, {"prompt": "What are the surveillance objectives for Epilepsy? related to Yellow Fever Disease", "completion": "The goals are to ensure early detection and immediate intervention to reduce the morbidity and mortality rates associated with epilepsy. Additionally, registering and monitoring epilepsy cases is vital."}, {"prompt": "What defines a suspected case of Epilepsy? related to Yellow Fever Disease", "completion": "Suspected Case: Any person with one epileptic seizure. Probable Case: Only the first diagnosis of the case in the health centre. Confirmed Case: Any person with a recurrence of at least two epileptic seizures. A positive response to treatment with any anti-epileptic drug (AED) strengthens the hypothesis of a confirmed case. Seizures can last from 30 seconds to 3 minutes, and intertwined seizures without a pause can lead to status epilepticus."}, {"prompt": "How is a suspected case of Epilepsy defined? related to Yellow Fever Disease", "completion": "Suspected Case: Any person with one epileptic seizure. Probable Case: Only the first diagnosis of the case in the health centre. Confirmed Case: Any person with a recurrence of at least two epileptic seizures. A positive response to treatment with any anti-epileptic drug (AED) strengthens the hypothesis of a confirmed case. Seizures can last from 30 seconds to 3 minutes, and intertwined seizures without a pause can lead to status epilepticus."}, {"prompt": "What are the criteria for diagnosing Epilepsy as a suspected case? related to Yellow Fever Disease", "completion": "Suspected Case: Any person with one epileptic seizure. Probable Case: Only the first diagnosis of the case in the health centre. Confirmed Case: Any person with a recurrence of at least two epileptic seizures. A positive response to treatment with any anti-epileptic drug (AED) strengthens the hypothesis of a confirmed case. Seizures can last from 30 seconds to 3 minutes, and intertwined seizures without a pause can lead to status epilepticus."}, {"prompt": "How should you respond to a suspected or confirmed case of Epilepsy? related to Yellow Fever Disease", "completion": "For suspected cases, health personnel should check for early signs of epilepsy. The diagnosis should include thorough interviews and clinical examinations. Upon diagnosis, search for underlying and associated causes. Check for any unusual increase in the number of cases and propose environmental measures if needed. For confirmed cases, immediate treatment is crucial. Treatment begins with low doses of any anti-epileptic drug and is progressively increased until an effective steady state is reached. If seizures persist despite pharmacological treatment or if the first seizure occurs in an adult aged 30 or above, a referral to a higher-level health facility is recommended."}, {"prompt": "How should healthcare professionals respond to a suspected or confirmed case of Epilepsy? related to Yellow Fever Disease", "completion": "For suspected cases, health personnel should check for early signs of epilepsy. The diagnosis should include thorough interviews and clinical examinations. Upon diagnosis, search for underlying and associated causes. Check for any unusual increase in the number of cases and propose environmental measures if needed. For confirmed cases, immediate treatment is crucial. Treatment begins with low doses of any anti-epileptic drug and is progressively increased until an effective steady state is reached. If seizures persist despite pharmacological treatment or if the first seizure occurs in an adult aged 30 or above, a referral to a higher-level health facility is recommended."}, {"prompt": "How should healthcare providers respond to a suspected or confirmed case of Epilepsy? related to Yellow Fever Disease", "completion": "For suspected cases, health personnel should check for early signs of epilepsy. The diagnosis should include thorough interviews and clinical examinations. Upon diagnosis, search for underlying and associated causes. Check for any unusual increase in the number of cases and propose environmental measures if needed. For confirmed cases, immediate treatment is crucial. Treatment begins with low doses of any anti-epileptic drug and is progressively increased until an effective steady state is reached. If seizures persist despite pharmacological treatment or if the first seizure occurs in an adult aged 30 or above, a referral to a higher-level health facility is recommended."}, {"prompt": "How should healthcare workers respond to a suspected or confirmed case of Epilepsy? related to Yellow Fever Disease", "completion": "For suspected cases, health personnel should check for early signs of epilepsy. The diagnosis should include thorough interviews and clinical examinations. Upon diagnosis, search for underlying and associated causes. Check for any unusual increase in the number of cases and propose environmental measures if needed. For confirmed cases, immediate treatment is crucial. Treatment begins with low doses of any anti-epileptic drug and is progressively increased until an effective steady state is reached. If seizures persist despite pharmacological treatment or if the first seizure occurs in an adult aged 30 or above, a referral to a higher-level health facility is recommended."}, {"prompt": "How should all cases of Epilepsy be handled? related to Yellow Fever Disease", "completion": "Information and education measures on epilepsy and its risk factors should be disseminated at the community level."}, {"prompt": "What actions should be taken for all individuals with Epilepsy? related to Yellow Fever Disease", "completion": "Information and education measures on epilepsy and its risk factors should be disseminated at the community level."}, {"prompt": "How can community awareness about Epilepsy be improved? related to Yellow Fever Disease", "completion": "Information and education measures on epilepsy and its risk factors should be disseminated at the community level."}, {"prompt": "What steps should be taken to raise awareness about Epilepsy? related to Yellow Fever Disease", "completion": "Information and education measures on epilepsy and its risk factors should be disseminated at the community level."}, {"prompt": "How should data about individuals with Epilepsy be analyzed and interpreted? related to Yellow Fever Disease", "completion": "The sex and age distribution (by age group from 6 years onwards) should be analyzed."}, {"prompt": "What methods can be used to analyze data about individuals with Epilepsy? related to Yellow Fever Disease", "completion": "The sex and age distribution (by age group from 6 years onwards) should be analyzed."}, {"prompt": "How can you analyze and interpret data about individuals with Epilepsy? related to Yellow Fever Disease", "completion": "The sex and age distribution (by age group from 6 years onwards) should be analyzed."}, {"prompt": "What are the ways to analyze data about individuals with Epilepsy? related to Yellow Fever Disease", "completion": "The sex and age distribution (by age group from 6 years onwards) should be analyzed."}, {"prompt": "How should time-related data about Epilepsy be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly."}, {"prompt": "What methods can be used to analyze time-related data about Epilepsy? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly."}, {"prompt": "How can you analyze and interpret time-related data about Epilepsy? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly."}, {"prompt": "What are the ways to analyze time-related data about Epilepsy? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly."}, {"prompt": "How should data about the location of individuals with Epilepsy be analyzed and interpreted? related to Yellow Fever Disease", "completion": "The distribution should be plotted by area of residence."}, {"prompt": "What methods can be used to analyze data about the location of individuals with Epilepsy? related to Yellow Fever Disease", "completion": "The distribution should be plotted by area of residence."}, {"prompt": "How can you analyze and interpret data about the location of individuals with Epilepsy? related to Yellow Fever Disease", "completion": "The distribution should be plotted by area of residence."}, {"prompt": "What are the ways to analyze data about the location of individuals with Epilepsy? related to Yellow Fever Disease", "completion": "The distribution should be plotted by area of residence."}, {"prompt": "How is Epilepsy diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Blood glucose levels (both random capillary and venous blood sugar) and electrolytes are checked to rule out other conditions like diabetes or kidney pathology. Conditions like Cerebral Malaria, meningitis, and toxoplasmosis need to be excluded by conducting appropriate medical investigations. The primary diagnostic test involves the microscopic examination of cerebral spinal fluid (CSF) to detect any abnormalities. Specimens should be collected using universal precautions and transported appropriately. Results are typically available within 1 to 3 hours from their arrival in the laboratory."}, {"prompt": "What are the laboratory methods for diagnosing Epilepsy? related to Yellow Fever Disease", "completion": "Blood glucose levels (both random capillary and venous blood sugar) and electrolytes are checked to rule out other conditions like diabetes or kidney pathology. Conditions like Cerebral Malaria, meningitis, and toxoplasmosis need to be excluded by conducting appropriate medical investigations. The primary diagnostic test involves the microscopic examination of cerebral spinal fluid (CSF) to detect any abnormalities. Specimens should be collected using universal precautions and transported appropriately. Results are typically available within 1 to 3 hours from their arrival in the laboratory."}, {"prompt": "How is the laboratory diagnosis of Epilepsy performed? related to Yellow Fever Disease", "completion": "Blood glucose levels (both random capillary and venous blood sugar) and electrolytes are checked to rule out other conditions like diabetes or kidney pathology. Conditions like Cerebral Malaria, meningitis, and toxoplasmosis need to be excluded by conducting appropriate medical investigations. The primary diagnostic test involves the microscopic examination of cerebral spinal fluid (CSF) to detect any abnormalities. Specimens should be collected using universal precautions and transported appropriately. Results are typically available within 1 to 3 hours from their arrival in the laboratory."}, {"prompt": "What are the references for Epilepsy? related to Yellow Fever Disease", "completion": "1. WHO, Epilepsy in the WHO African Region: Bridging the Gap, WHO Regional Office for Africa, Congo, 2004.\n2. WHO, Epilepsy: a manual for medical and clinical officers in Africa, World health, Geneva 2002."}, {"prompt": "Explain Meningococcal Meningitis. related to Yellow Fever Disease", "completion": "Meningococcal meningitis is caused by Neisseria meningitidis, Haemophilus influenzae type b (Hib), and Streptococcus pneumoniae, which constitute the majority of all cases of bacterial meningitis and 90% of bacterial meningitis in children. It is a significant public health challenge in the African meningitis belt, an area stretching from Senegal to Ethiopia. Large outbreaks often occur during the dry season. Human-to-human transmission is through large respiratory droplets from the noses and throats of infected individuals. The incubation period ranges from 2 to 10 days. Children, especially those with vitamin A deficiency and malnutrition, are at high risk. Most cases are treatable, but untreated cases have high fatality rates. Epidemics in the belt are often associated with Neisseria meningitidis serogroup A, but other serogroups have caused outbreaks. A new meningococcal A conjugate vaccine has been developed, which offers longer-term protection and is expected to significantly reduce epidemics."}, {"prompt": "Describe Meningococcal Meningitis. related to Yellow Fever Disease", "completion": "Meningococcal meningitis is caused by Neisseria meningitidis, Haemophilus influenzae type b (Hib), and Streptococcus pneumoniae, which constitute the majority of all cases of bacterial meningitis and 90% of bacterial meningitis in children. It is a significant public health challenge in the African meningitis belt, an area stretching from Senegal to Ethiopia. Large outbreaks often occur during the dry season. Human-to-human transmission is through large respiratory droplets from the noses and throats of infected individuals. The incubation period ranges from 2 to 10 days. Children, especially those with vitamin A deficiency and malnutrition, are at high risk. Most cases are treatable, but untreated cases have high fatality rates. Epidemics in the belt are often associated with Neisseria meningitidis serogroup A, but other serogroups have caused outbreaks. A new meningococcal A conjugate vaccine has been developed, which offers longer-term protection and is expected to significantly reduce epidemics."}, {"prompt": "Elaborate on Meningococcal Meningitis. related to Yellow Fever Disease", "completion": "Meningococcal meningitis is caused by Neisseria meningitidis, Haemophilus influenzae type b (Hib), and Streptococcus pneumoniae, which constitute the majority of all cases of bacterial meningitis and 90% of bacterial meningitis in children. It is a significant public health challenge in the African meningitis belt, an area stretching from Senegal to Ethiopia. Large outbreaks often occur during the dry season. Human-to-human transmission is through large respiratory droplets from the noses and throats of infected individuals. The incubation period ranges from 2 to 10 days. Children, especially those with vitamin A deficiency and malnutrition, are at high risk. Most cases are treatable, but untreated cases have high fatality rates. Epidemics in the belt are often associated with Neisseria meningitidis serogroup A, but other serogroups have caused outbreaks. A new meningococcal A conjugate vaccine has been developed, which offers longer-term protection and is expected to significantly reduce epidemics."}, {"prompt": "Define Meningococcal Meningitis. related to Yellow Fever Disease", "completion": "Meningococcal meningitis is caused by Neisseria meningitidis, Haemophilus influenzae type b (Hib), and Streptococcus pneumoniae, which constitute the majority of all cases of bacterial meningitis and 90% of bacterial meningitis in children. It is a significant public health challenge in the African meningitis belt, an area stretching from Senegal to Ethiopia. Large outbreaks often occur during the dry season. Human-to-human transmission is through large respiratory droplets from the noses and throats of infected individuals. The incubation period ranges from 2 to 10 days. Children, especially those with vitamin A deficiency and malnutrition, are at high risk. Most cases are treatable, but untreated cases have high fatality rates. Epidemics in the belt are often associated with Neisseria meningitidis serogroup A, but other serogroups have caused outbreaks. A new meningococcal A conjugate vaccine has been developed, which offers longer-term protection and is expected to significantly reduce epidemics."}, {"prompt": "What is the nature of Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "Meningococcal meningitis is caused by Neisseria meningitidis, Haemophilus influenzae type b (Hib), and Streptococcus pneumoniae, which constitute the majority of all cases of bacterial meningitis and 90% of bacterial meningitis in children. It is a significant public health challenge in the African meningitis belt, an area stretching from Senegal to Ethiopia. Large outbreaks often occur during the dry season. Human-to-human transmission is through large respiratory droplets from the noses and throats of infected individuals. The incubation period ranges from 2 to 10 days. Children, especially those with vitamin A deficiency and malnutrition, are at high risk. Most cases are treatable, but untreated cases have high fatality rates. Epidemics in the belt are often associated with Neisseria meningitidis serogroup A, but other serogroups have caused outbreaks. A new meningococcal A conjugate vaccine has been developed, which offers longer-term protection and is expected to significantly reduce epidemics."}, {"prompt": "Why is Meningococcal Meningitis a priority in public health? related to Yellow Fever Disease", "completion": "Meningococcal Meningitis is prioritized because of its high case fatality rates, which are usually 8-15% among treated patients and over 70% among untreated cases. Many survivors suffer from long-term complications such as mental retardation, hearing loss, and loss of limb function."}, {"prompt": "What makes Meningococcal Meningitis a priority in public health? related to Yellow Fever Disease", "completion": "Meningococcal Meningitis is prioritized because of its high case fatality rates, which are usually 8-15% among treated patients and over 70% among untreated cases. Many survivors suffer from long-term complications such as mental retardation, hearing loss, and loss of limb function."}, {"prompt": "What are the reasons behind considering Meningococcal Meningitis a priority? related to Yellow Fever Disease", "completion": "Meningococcal Meningitis is prioritized because of its high case fatality rates, which are usually 8-15% among treated patients and over 70% among untreated cases. Many survivors suffer from long-term complications such as mental retardation, hearing loss, and loss of limb function."}, {"prompt": "What factors contribute to the priority of Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "Meningococcal Meningitis is prioritized because of its high case fatality rates, which are usually 8-15% among treated patients and over 70% among untreated cases. Many survivors suffer from long-term complications such as mental retardation, hearing loss, and loss of limb function."}, {"prompt": "What are the surveillance objectives for Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "The goals include promptly detecting meningitis outbreaks, confirming the cause of outbreaks, using the data to plan for treatment and vaccination supplies, assessing and monitoring the spread and progress of the epidemic, evaluating the effectiveness of control measures, and conducting periodic susceptibility testing for penicillin and chloramphenicol."}, {"prompt": "What are the aims of Meningococcal Meningitis surveillance? related to Yellow Fever Disease", "completion": "The goals include promptly detecting meningitis outbreaks, confirming the cause of outbreaks, using the data to plan for treatment and vaccination supplies, assessing and monitoring the spread and progress of the epidemic, evaluating the effectiveness of control measures, and conducting periodic susceptibility testing for penicillin and chloramphenicol."}, {"prompt": "What is the standard case definition for a suspected case of Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "Suspected Case: Any person with sudden onset of fever (>38.5\u00b0C rectal or 38.0\u00b0C axillary) and one of the following signs: neck stiffness, altered consciousness or other meningeal signs. Confirmed Case: A suspected case with the isolation of N. meningitidis from CSF or blood."}, {"prompt": "Define a suspected case of Meningococcal Meningitis. related to Yellow Fever Disease", "completion": "Suspected Case: Any person with sudden onset of fever (>38.5\u00b0C rectal or 38.0\u00b0C axillary) and one of the following signs: neck stiffness, altered consciousness or other meningeal signs. Confirmed Case: A suspected case with the isolation of N. meningitidis from CSF or blood."}, {"prompt": "What are the criteria for a suspected case of Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "Suspected Case: Any person with sudden onset of fever (>38.5\u00b0C rectal or 38.0\u00b0C axillary) and one of the following signs: neck stiffness, altered consciousness or other meningeal signs. Confirmed Case: A suspected case with the isolation of N. meningitidis from CSF or blood."}, {"prompt": "How should you respond when an alert threshold is reached for Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "For populations between 30,000 and 100,000, an alert is triggered with an attack rate of 5 cases per 100,000 inhabitants per week. For populations below 30,000, 2 cases in 1 week or an increase compared to previous non-epidemic years prompts an alert. The response includes informing the next level of the health system, recording cases, laboratory confirmation, treating all suspected cases as per national protocols, intensifying surveillance, and preparing for a mass vaccination campaign."}, {"prompt": "What actions should be taken when an alert threshold is reached for Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "For populations between 30,000 and 100,000, an alert is triggered with an attack rate of 5 cases per 100,000 inhabitants per week. For populations below 30,000, 2 cases in 1 week or an increase compared to previous non-epidemic years prompts an alert. The response includes informing the next level of the health system, recording cases, laboratory confirmation, treating all suspected cases as per national protocols, intensifying surveillance, and preparing for a mass vaccination campaign."}, {"prompt": "How should you respond when an action threshold is reached for Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "For populations between 30,000 and 100,000, the epidemic threshold is an attack rate of 15 cases per 100,000 inhabitants per week. When the risk of an epidemic is high, the threshold is 10 cases per 100,000 per week. For populations below 30,000, 5 cases in a week or the doubling of cases over 3 weeks indicates an epidemic. The response involves vaccinating affected areas, mobilizing the community for early detection and treatment, continued data collection and analysis, maintaining specimen collection to detect serogroup shifts, and treating all cases as per national protocols."}, {"prompt": "What actions should be taken when an action threshold is reached for Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "For populations between 30,000 and 100,000, the epidemic threshold is an attack rate of 15 cases per 100,000 inhabitants per week. When the risk of an epidemic is high, the threshold is 10 cases per 100,000 per week. For populations below 30,000, 5 cases in a week or the doubling of cases over 3 weeks indicates an epidemic. The response involves vaccinating affected areas, mobilizing the community for early detection and treatment, continued data collection and analysis, maintaining specimen collection to detect serogroup shifts, and treating all cases as per national protocols."}, {"prompt": "How should data about individuals with Meningococcal Meningitis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count total sporadic and outbreak cases. Analyze the age distribution of cases."}, {"prompt": "What methods are used for analyzing data about individuals with Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "Count total sporadic and outbreak cases. Analyze the age distribution of cases."}, {"prompt": "How can we interpret the data on individuals with Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "Count total sporadic and outbreak cases. Analyze the age distribution of cases."}, {"prompt": "What are the techniques for interpreting data about individuals with Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "Count total sporadic and outbreak cases. Analyze the age distribution of cases."}, {"prompt": "How should data about time in the context of Meningococcal Meningitis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "In the meningitis belt during the epidemic season, graph weekly cases and deaths. Otherwise, graph monthly trends in cases and deaths. Construct an epidemic curve for outbreak cases. The target case fatality rate is less than 10%."}, {"prompt": "What methods are used for temporal analysis of Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "In the meningitis belt during the epidemic season, graph weekly cases and deaths. Otherwise, graph monthly trends in cases and deaths. Construct an epidemic curve for outbreak cases. The target case fatality rate is less than 10%."}, {"prompt": "How can we interpret time-related data about Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "In the meningitis belt during the epidemic season, graph weekly cases and deaths. Otherwise, graph monthly trends in cases and deaths. Construct an epidemic curve for outbreak cases. The target case fatality rate is less than 10%."}, {"prompt": "What are the techniques for temporal analysis of Meningococcal Meningitis data? related to Yellow Fever Disease", "completion": "In the meningitis belt during the epidemic season, graph weekly cases and deaths. Otherwise, graph monthly trends in cases and deaths. Construct an epidemic curve for outbreak cases. The target case fatality rate is less than 10%."}, {"prompt": "How should data about place in the context of Meningococcal Meningitis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "In epidemics (not endemic situations), plot the location of case households and estimate the distance to the nearest health facility."}, {"prompt": "What methods are used for spatial analysis of Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "In epidemics (not endemic situations), plot the location of case households and estimate the distance to the nearest health facility."}, {"prompt": "How can we interpret spatial data about Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "In epidemics (not endemic situations), plot the location of case households and estimate the distance to the nearest health facility."}, {"prompt": "What are the techniques for spatial analysis of Meningococcal Meningitis data? related to Yellow Fever Disease", "completion": "In epidemics (not endemic situations), plot the location of case households and estimate the distance to the nearest health facility."}, {"prompt": "How are Meningococcal Meningitis diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Diagnosis is through microscopic examination of CSF for Gram-negative diplococci and the culture and isolation of N. meningitidis from CSF. The specimen of choice is cerebral spinal fluid (CSF). Specimens should be collected from 5 to 10 cases once the alert or epidemic threshold has been reached. Specimens should be kept at 4\u00b0C and transported appropriately. Results typically involve the isolation of Neiseria meningitidis. Specimen preparation and handling are critical due to the organism's fastidious nature. Regular susceptibility testing should be performed to ensure appropriate treatment."}, {"prompt": "What laboratory procedures are involved in the diagnosis of Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "Diagnosis is through microscopic examination of CSF for Gram-negative diplococci and the culture and isolation of N. meningitidis from CSF. The specimen of choice is cerebral spinal fluid (CSF). Specimens should be collected from 5 to 10 cases once the alert or epidemic threshold has been reached. Specimens should be kept at 4\u00b0C and transported appropriately. Results typically involve the isolation of Neiseria meningitidis. Specimen preparation and handling are critical due to the organism's fastidious nature. Regular susceptibility testing should be performed to ensure appropriate treatment."}, {"prompt": "How is Meningococcal Meningitis confirmed in the laboratory? related to Yellow Fever Disease", "completion": "Diagnosis is through microscopic examination of CSF for Gram-negative diplococci and the culture and isolation of N. meningitidis from CSF. The specimen of choice is cerebral spinal fluid (CSF). Specimens should be collected from 5 to 10 cases once the alert or epidemic threshold has been reached. Specimens should be kept at 4\u00b0C and transported appropriately. Results typically involve the isolation of Neiseria meningitidis. Specimen preparation and handling are critical due to the organism's fastidious nature. Regular susceptibility testing should be performed to ensure appropriate treatment."}, {"prompt": "What are the references for Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "1. Weekly Epidemiological Record N 38, September 2000 (http: //www.who.int/wer/pdf/2000/wer7538.pdf)\n2. WHO Regional Office for Africa Standard Operating Procedures for Enhanced Meningitis Surveillance in Africa, August 2009\n3. Control of epidemic meningococcal disease. WHO Practical Guidelines, 2nd Edition. WHO/EMC/BAC/98.3.\n4. Laboratory Methods for the Diagnosis of Meningitis Caused by Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae. WHO document WHO/CDS/EDC/99.7 WHO, Geneva"}, {"prompt": "What are the sources for information about Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "1. Weekly Epidemiological Record N 38, September 2000 (http: //www.who.int/wer/pdf/2000/wer7538.pdf)\n2. WHO Regional Office for Africa Standard Operating Procedures for Enhanced Meningitis Surveillance in Africa, August 2009\n3. Control of epidemic meningococcal disease. WHO Practical Guidelines, 2nd Edition. WHO/EMC/BAC/98.3.\n4. Laboratory Methods for the Diagnosis of Meningitis Caused by Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae. WHO document WHO/CDS/EDC/99.7 WHO, Geneva"}, {"prompt": "Where can I find relevant information about Meningococcal Meningitis? related to Yellow Fever Disease", "completion": "1. Weekly Epidemiological Record N 38, September 2000 (http: //www.who.int/wer/pdf/2000/wer7538.pdf)\n2. WHO Regional Office for Africa Standard Operating Procedures for Enhanced Meningitis Surveillance in Africa, August 2009\n3. Control of epidemic meningococcal disease. WHO Practical Guidelines, 2nd Edition. WHO/EMC/BAC/98.3.\n4. Laboratory Methods for the Diagnosis of Meningitis Caused by Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae. WHO document WHO/CDS/EDC/99.7 WHO, Geneva"}, {"prompt": "What are the recommended sources for Meningococcal Meningitis information? related to Yellow Fever Disease", "completion": "1. Weekly Epidemiological Record N 38, September 2000 (http: //www.who.int/wer/pdf/2000/wer7538.pdf)\n2. WHO Regional Office for Africa Standard Operating Procedures for Enhanced Meningitis Surveillance in Africa, August 2009\n3. Control of epidemic meningococcal disease. WHO Practical Guidelines, 2nd Edition. WHO/EMC/BAC/98.3.\n4. Laboratory Methods for the Diagnosis of Meningitis Caused by Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae. WHO document WHO/CDS/EDC/99.7 WHO, Geneva"}, {"prompt": "Explain Measles. related to Yellow Fever Disease", "completion": "Measles is a febrile rash illness due to paramyxovirus (Morbillivirus) transmitted human-to-human via airborne droplet spread. It is the fourth leading cause of death in children less than 5 years of age in many African countries. The incubation period is 7 to 18 days from exposure to onset of fever. Among children with vitamin A deficiency and malnutrition, measles may result in severe illness due to the virus itself and associated bacterial infections, especially pneumonia; only the minority of cases are severe."}, {"prompt": "What is the nature of Measles? related to Yellow Fever Disease", "completion": "Measles is a febrile rash illness due to paramyxovirus (Morbillivirus) transmitted human-to-human via airborne droplet spread. It is the fourth leading cause of death in children less than 5 years of age in many African countries. The incubation period is 7 to 18 days from exposure to onset of fever. Among children with vitamin A deficiency and malnutrition, measles may result in severe illness due to the virus itself and associated bacterial infections, especially pneumonia; only the minority of cases are severe."}, {"prompt": "Describe Measles. related to Yellow Fever Disease", "completion": "Measles is a febrile rash illness due to paramyxovirus (Morbillivirus) transmitted human-to-human via airborne droplet spread. It is the fourth leading cause of death in children less than 5 years of age in many African countries. The incubation period is 7 to 18 days from exposure to onset of fever. Among children with vitamin A deficiency and malnutrition, measles may result in severe illness due to the virus itself and associated bacterial infections, especially pneumonia; only the minority of cases are severe."}, {"prompt": "Elaborate on Measles. related to Yellow Fever Disease", "completion": "Measles is a febrile rash illness due to paramyxovirus (Morbillivirus) transmitted human-to-human via airborne droplet spread. It is the fourth leading cause of death in children less than 5 years of age in many African countries. The incubation period is 7 to 18 days from exposure to onset of fever. Among children with vitamin A deficiency and malnutrition, measles may result in severe illness due to the virus itself and associated bacterial infections, especially pneumonia; only the minority of cases are severe."}, {"prompt": "Define Measles. related to Yellow Fever Disease", "completion": "Measles is a febrile rash illness due to paramyxovirus (Morbillivirus) transmitted human-to-human via airborne droplet spread. It is the fourth leading cause of death in children less than 5 years of age in many African countries. The incubation period is 7 to 18 days from exposure to onset of fever. Among children with vitamin A deficiency and malnutrition, measles may result in severe illness due to the virus itself and associated bacterial infections, especially pneumonia; only the minority of cases are severe."}, {"prompt": "Why is Measles a global health priority? related to Yellow Fever Disease", "completion": "Measles is among the most transmissible of human infections. Large outbreaks occur every few years in areas with low vaccine coverage and where there is an accumulation of persons who have never been infected or vaccinated. The true incidence of measles far exceeds reported cases."}, {"prompt": "What makes Measles a priority in global health efforts? related to Yellow Fever Disease", "completion": "Measles is among the most transmissible of human infections. Large outbreaks occur every few years in areas with low vaccine coverage and where there is an accumulation of persons who have never been infected or vaccinated. The true incidence of measles far exceeds reported cases."}, {"prompt": "What are the reasons behind Measles being a global health priority? related to Yellow Fever Disease", "completion": "Measles is among the most transmissible of human infections. Large outbreaks occur every few years in areas with low vaccine coverage and where there is an accumulation of persons who have never been infected or vaccinated. The true incidence of measles far exceeds reported cases."}, {"prompt": "Who is most vulnerable to Measles? related to Yellow Fever Disease", "completion": "Measles is among the most transmissible of human infections. Large outbreaks occur every few years in areas with low vaccine coverage and where there is an accumulation of persons who have never been infected or vaccinated. The true incidence of measles far exceeds reported cases."}, {"prompt": "Who are the individuals most susceptible to Measles? related to Yellow Fever Disease", "completion": "Measles is among the most transmissible of human infections. Large outbreaks occur every few years in areas with low vaccine coverage and where there is an accumulation of persons who have never been infected or vaccinated. The true incidence of measles far exceeds reported cases."}, {"prompt": "What groups of people are at the highest risk of Measles? related to Yellow Fever Disease", "completion": "Measles is among the most transmissible of human infections. Large outbreaks occur every few years in areas with low vaccine coverage and where there is an accumulation of persons who have never been infected or vaccinated. The true incidence of measles far exceeds reported cases."}, {"prompt": "What are the surveillance objectives for Measles? related to Yellow Fever Disease", "completion": "Detect outbreaks of fever with rash illness promptly. In countries with a measles elimination target: immediate case-based reporting of suspected cases and deaths of fever with rash illness; confirm all suspected measles cases with laboratory test (usually serum IgM). In countries with accelerated measles control programs: Summary reporting of cases and deaths for routine surveillance and outbreaks; confirm the first five cases of suspected measles in a health facility per week with laboratory test (usually serum IgM). Uganda's target is to achieve measles elimination by 2020."}, {"prompt": "What is the purpose of Measles surveillance? related to Yellow Fever Disease", "completion": "Detect outbreaks of fever with rash illness promptly. In countries with a measles elimination target: immediate case-based reporting of suspected cases and deaths of fever with rash illness; confirm all suspected measles cases with laboratory test (usually serum IgM). In countries with accelerated measles control programs: Summary reporting of cases and deaths for routine surveillance and outbreaks; confirm the first five cases of suspected measles in a health facility per week with laboratory test (usually serum IgM). Uganda's target is to achieve measles elimination by 2020."}, {"prompt": "What are the goals of Measles surveillance? related to Yellow Fever Disease", "completion": "Detect outbreaks of fever with rash illness promptly. In countries with a measles elimination target: immediate case-based reporting of suspected cases and deaths of fever with rash illness; confirm all suspected measles cases with laboratory test (usually serum IgM). In countries with accelerated measles control programs: Summary reporting of cases and deaths for routine surveillance and outbreaks; confirm the first five cases of suspected measles in a health facility per week with laboratory test (usually serum IgM). Uganda's target is to achieve measles elimination by 2020."}, {"prompt": "What is the standard case definition for Measles? related to Yellow Fever Disease", "completion": "Suspected Case: Any person with fever and maculopapular (non-vesicular) generalized rash and cough, coryza or conjunctivitis (red eyes) or any person in whom a clinician suspects measles. Confirmed Case: A suspected case with laboratory confirmation (positive IgM antibody) or epidemiological link to confirmed cases in an outbreak."}, {"prompt": "Define a suspected case of Measles. related to Yellow Fever Disease", "completion": "Suspected Case: Any person with fever and maculopapular (non-vesicular) generalized rash and cough, coryza or conjunctivitis (red eyes) or any person in whom a clinician suspects measles. Confirmed Case: A suspected case with laboratory confirmation (positive IgM antibody) or epidemiological link to confirmed cases in an outbreak."}, {"prompt": "What is the criteria for confirming a Measles case? related to Yellow Fever Disease", "completion": "Suspected Case: Any person with fever and maculopapular (non-vesicular) generalized rash and cough, coryza or conjunctivitis (red eyes) or any person in whom a clinician suspects measles. Confirmed Case: A suspected case with laboratory confirmation (positive IgM antibody) or epidemiological link to confirmed cases in an outbreak."}, {"prompt": "What actions should be taken upon reaching an alert threshold for Measles? related to Yellow Fever Disease", "completion": "If an outbreak is suspected: Report suspected case to the next level. Collect blood samples from the first five cases to confirm the outbreak. Line list the other cases without collecting any blood samples. Treat cases with oral rehydration, vitamin A, and antibiotics for prevention of bacterial super-infection. Use airborne isolation precautions where feasible. Investigate the case or outbreak to identify causes for outbreak."}, {"prompt": "How should you respond to an alert threshold for Measles? related to Yellow Fever Disease", "completion": "If an outbreak is suspected: Report suspected case to the next level. Collect blood samples from the first five cases to confirm the outbreak. Line list the other cases without collecting any blood samples. Treat cases with oral rehydration, vitamin A, and antibiotics for prevention of bacterial super-infection. Use airborne isolation precautions where feasible. Investigate the case or outbreak to identify causes for outbreak."}, {"prompt": "What measures should be taken in response to an action threshold for Measles? related to Yellow Fever Disease", "completion": "If an outbreak is confirmed: Improve routine vaccine coverage through the EPI, and lead supplemental vaccination activities in areas of low vaccine coverage. Mobilize the community early to enable rapid case detection and treatment."}, {"prompt": "What steps should be taken when reaching an action threshold for Measles? related to Yellow Fever Disease", "completion": "If an outbreak is confirmed: Improve routine vaccine coverage through the EPI, and lead supplemental vaccination activities in areas of low vaccine coverage. Mobilize the community early to enable rapid case detection and treatment."}, {"prompt": "How should data about a person with Measles be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count total cases and analyze by age group and immunization status."}, {"prompt": "What methods are used to analyze data about individuals with Measles? related to Yellow Fever Disease", "completion": "Count total cases and analyze by age group and immunization status."}, {"prompt": "How can we interpret data on Measles cases and individuals? related to Yellow Fever Disease", "completion": "Count total cases and analyze by age group and immunization status."}, {"prompt": "How should data about time in the context of Measles be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends. Graph weekly cases and deaths. Construct an epidemic curve for outbreak cases."}, {"prompt": "What are the techniques used for temporal analysis of Measles cases? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends. Graph weekly cases and deaths. Construct an epidemic curve for outbreak cases."}, {"prompt": "How can temporal analysis help in understanding Measles trends? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends. Graph weekly cases and deaths. Construct an epidemic curve for outbreak cases."}, {"prompt": "How should data about place in the context of Measles be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "What methods are used for spatial analysis of Measles cases? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "How can spatial analysis contribute to understanding Measles transmission? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "What are the laboratory procedures for diagnosing Measles? related to Yellow Fever Disease", "completion": "Measles is diagnosed in the laboratory through the presence of IgM antibodies to measles virus in serum. The specimen used is serum whole blood. Specimens should be collected within the first 30 days of rash onset. Blood samples should be collected on 5 suspected measles cases when the number of cases exceeds the measles outbreak threshold. In countries with an elimination target, a specimen should be collected from every suspected case of measles. Specimens should be stored at 4\u00b0C and transported using appropriate packaging. Results are typically available after 7 days. If as few as 3 out of 5 suspected measles cases are laboratory confirmed, the outbreak is confirmed."}, {"prompt": "How is Measles diagnosed using laboratory techniques? related to Yellow Fever Disease", "completion": "Measles is diagnosed in the laboratory through the presence of IgM antibodies to measles virus in serum. The specimen used is serum whole blood. Specimens should be collected within the first 30 days of rash onset. Blood samples should be collected on 5 suspected measles cases when the number of cases exceeds the measles outbreak threshold. In countries with an elimination target, a specimen should be collected from every suspected case of measles. Specimens should be stored at 4\u00b0C and transported using appropriate packaging. Results are typically available after 7 days. If as few as 3 out of 5 suspected measles cases are laboratory confirmed, the outbreak is confirmed."}, {"prompt": "What are the sources of information for Measles? related to Yellow Fever Disease", "completion": "1. Field guide for training operational level health workers on vaccine preventable disease surveillance, MoH/ UNEPI (Revised edition 2012)\n2. Using surveillance data and outbreak investigations to strengthen measles immunization programs, Geneva, World Health Organization. WHO/EPI/GEN/96.02\n3. WHO Guidelines for Epidemic Preparedness and Response to Measles Outbreaks WHO/CDS/CSR/ISR/99.1"}, {"prompt": "Where can I find more references about Measles? related to Yellow Fever Disease", "completion": "1. Field guide for training operational level health workers on vaccine preventable disease surveillance, MoH/ UNEPI (Revised edition 2012)\n2. Using surveillance data and outbreak investigations to strengthen measles immunization programs, Geneva, World Health Organization. WHO/EPI/GEN/96.02\n3. WHO Guidelines for Epidemic Preparedness and Response to Measles Outbreaks WHO/CDS/CSR/ISR/99.1"}, {"prompt": "Explain Maternal Deaths. related to Yellow Fever Disease", "completion": "Deaths during pregnancy, childbirth or termination of pregnancy, and deaths up to 6 weeks (42 days) after childbirth or termination of pregnancy related to pregnancy are considered Maternal Deaths. Hemorrhage is the leading cause of maternal death in sub-Saharan Africa, and unattended births are a particular risk, especially in rural areas where transport to health care facilities is a problem."}, {"prompt": "What are the causes of Maternal Deaths? related to Yellow Fever Disease", "completion": "Deaths during pregnancy, childbirth or termination of pregnancy, and deaths up to 6 weeks (42 days) after childbirth or termination of pregnancy related to pregnancy are considered Maternal Deaths. Hemorrhage is the leading cause of maternal death in sub-Saharan Africa, and unattended births are a particular risk, especially in rural areas where transport to health care facilities is a problem."}, {"prompt": "Describe Maternal Deaths. related to Yellow Fever Disease", "completion": "Deaths during pregnancy, childbirth or termination of pregnancy, and deaths up to 6 weeks (42 days) after childbirth or termination of pregnancy related to pregnancy are considered Maternal Deaths. Hemorrhage is the leading cause of maternal death in sub-Saharan Africa, and unattended births are a particular risk, especially in rural areas where transport to health care facilities is a problem."}, {"prompt": "What are Maternal Mortalities? related to Yellow Fever Disease", "completion": "Deaths during pregnancy, childbirth or termination of pregnancy, and deaths up to 6 weeks (42 days) after childbirth or termination of pregnancy related to pregnancy are considered Maternal Deaths. Hemorrhage is the leading cause of maternal death in sub-Saharan Africa, and unattended births are a particular risk, especially in rural areas where transport to health care facilities is a problem."}, {"prompt": "Why are Maternal Deaths a global health concern? related to Yellow Fever Disease", "completion": "Globally, about 80% of maternal deaths are due to severe bleeding (mostly bleeding postpartum), infections (also mostly soon after delivery), hypertensive disorders in pregnancy (eclampsia) and obstructed labor. Complications after unsafe abortion cause 13% of maternal deaths. Across the developing world, maternal mortality levels remain too high, with more than 500,000 women dying every year as a result of complications during pregnancy and childbirth. About half of these deaths occur in sub-Saharan Africa where a woman's lifetime risk of maternal death is 1 in 22, compared with 1 in 8,000 in industrialized countries."}, {"prompt": "What makes Maternal Deaths a priority in global health efforts? related to Yellow Fever Disease", "completion": "Globally, about 80% of maternal deaths are due to severe bleeding (mostly bleeding postpartum), infections (also mostly soon after delivery), hypertensive disorders in pregnancy (eclampsia) and obstructed labor. Complications after unsafe abortion cause 13% of maternal deaths. Across the developing world, maternal mortality levels remain too high, with more than 500,000 women dying every year as a result of complications during pregnancy and childbirth. About half of these deaths occur in sub-Saharan Africa where a woman's lifetime risk of maternal death is 1 in 22, compared with 1 in 8,000 in industrialized countries."}, {"prompt": "What are the reasons behind addressing Maternal Deaths as a global health priority? related to Yellow Fever Disease", "completion": "Globally, about 80% of maternal deaths are due to severe bleeding (mostly bleeding postpartum), infections (also mostly soon after delivery), hypertensive disorders in pregnancy (eclampsia) and obstructed labor. Complications after unsafe abortion cause 13% of maternal deaths. Across the developing world, maternal mortality levels remain too high, with more than 500,000 women dying every year as a result of complications during pregnancy and childbirth. About half of these deaths occur in sub-Saharan Africa where a woman's lifetime risk of maternal death is 1 in 22, compared with 1 in 8,000 in industrialized countries."}, {"prompt": "Who is most vulnerable to Maternal Deaths? related to Yellow Fever Disease", "completion": "Those who are at the highest risk of maternal deaths include pregnant women, women in childbirth, and women who terminate pregnancy. Hemorrhage, infections, hypertensive disorders, and obstructed labor are common causes of maternal death. In sub-Saharan Africa, unattended births in rural areas pose a particular risk where transport to health care facilities is a problem."}, {"prompt": "Who are the individuals most susceptible to Maternal Deaths? related to Yellow Fever Disease", "completion": "Those who are at the highest risk of maternal deaths include pregnant women, women in childbirth, and women who terminate pregnancy. Hemorrhage, infections, hypertensive disorders, and obstructed labor are common causes of maternal death. In sub-Saharan Africa, unattended births in rural areas pose a particular risk where transport to health care facilities is a problem."}, {"prompt": "What groups of people are at the highest risk of Maternal Deaths? related to Yellow Fever Disease", "completion": "Those who are at the highest risk of maternal deaths include pregnant women, women in childbirth, and women who terminate pregnancy. Hemorrhage, infections, hypertensive disorders, and obstructed labor are common causes of maternal death. In sub-Saharan Africa, unattended births in rural areas pose a particular risk where transport to health care facilities is a problem."}, {"prompt": "What are the objectives of Maternal Deaths surveillance? related to Yellow Fever Disease", "completion": "Estimate and monitor maternal mortality rates. Identify risk factors and high risk areas for maternal mortality to inform program decisions. Evaluate programs aimed at reducing maternal mortality."}, {"prompt": "What are the targets for Maternal Deaths surveillance? related to Yellow Fever Disease", "completion": "Estimate and monitor maternal mortality rates. Identify risk factors and high risk areas for maternal mortality to inform program decisions. Evaluate programs aimed at reducing maternal mortality."}, {"prompt": "What are the goals of Maternal Deaths surveillance? related to Yellow Fever Disease", "completion": "Estimate and monitor maternal mortality rates. Identify risk factors and high risk areas for maternal mortality to inform program decisions. Evaluate programs aimed at reducing maternal mortality."}, {"prompt": "What is the case definition for Maternal Deaths? related to Yellow Fever Disease", "completion": "The death of a woman while pregnant or within 42 days of the delivery or termination of the pregnancy, irrespective of the duration and site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes."}, {"prompt": "How is a maternal death case defined? related to Yellow Fever Disease", "completion": "The death of a woman while pregnant or within 42 days of the delivery or termination of the pregnancy, irrespective of the duration and site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes."}, {"prompt": "What constitutes a maternal death according to the standard case definition? related to Yellow Fever Disease", "completion": "The death of a woman while pregnant or within 42 days of the delivery or termination of the pregnancy, irrespective of the duration and site of the pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes."}, {"prompt": "What public health actions are recommended for addressing Maternal Deaths? related to Yellow Fever Disease", "completion": "Establish alert thresholds to allow health facility or district health personnel determine when special targeted interventions are necessary. Monitor trends and respond to alert thresholds. Increase availability and use of antenatal care. Provide specialized training to traditional and professional birth attendants. Support interventions to improve recognition and response to high-risk pregnancies at the community level."}, {"prompt": "What measures can be taken to address Maternal Deaths? related to Yellow Fever Disease", "completion": "Establish alert thresholds to allow health facility or district health personnel determine when special targeted interventions are necessary. Monitor trends and respond to alert thresholds. Increase availability and use of antenatal care. Provide specialized training to traditional and professional birth attendants. Support interventions to improve recognition and response to high-risk pregnancies at the community level."}, {"prompt": "What actions are recommended to reduce Maternal Deaths? related to Yellow Fever Disease", "completion": "Establish alert thresholds to allow health facility or district health personnel determine when special targeted interventions are necessary. Monitor trends and respond to alert thresholds. Increase availability and use of antenatal care. Provide specialized training to traditional and professional birth attendants. Support interventions to improve recognition and response to high-risk pregnancies at the community level."}, {"prompt": "How should data about individuals with Maternal Deaths be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "What are the methods for analyzing data on individuals with Maternal Deaths? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "How can we interpret the data on Maternal Deaths individuals? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors."}, {"prompt": "How should data about time in the context of Maternal Deaths be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends."}, {"prompt": "What are the techniques for temporal analysis of Maternal Deaths? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends."}, {"prompt": "How can temporal analysis help in understanding Maternal Deaths trends? related to Yellow Fever Disease", "completion": "Graph cases to construct an epidemic curve throughout the year in order to identify trends."}, {"prompt": "How should data about place in the context of Maternal Deaths be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot the location of cases and analyze the distribution."}, {"prompt": "What are the methods used for spatial analysis of Maternal Deaths? related to Yellow Fever Disease", "completion": "Plot the location of cases and analyze the distribution."}, {"prompt": "How can spatial analysis contribute to understanding Maternal Deaths transmission? related to Yellow Fever Disease", "completion": "Plot the location of cases and analyze the distribution."}, {"prompt": "How are Maternal Deaths diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required for maternal deaths."}, {"prompt": "What laboratory procedures are used for diagnosing Maternal Deaths? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required for maternal deaths."}, {"prompt": "What are the references for Maternal Deaths? related to Yellow Fever Disease", "completion": "1. [World Health Organization on Maternal Mortality](http://www.who.int/making pregnancy safer/topics/maternal mortality/en/index.html)\n2. [UNICEF](http://www.unicef.org/index.php)"}, {"prompt": "Where can I find more information about Maternal Deaths? related to Yellow Fever Disease", "completion": "1. [World Health Organization on Maternal Mortality](http://www.who.int/making pregnancy safer/topics/maternal mortality/en/index.html)\n2. [UNICEF](http://www.unicef.org/index.php)"}, {"prompt": "Explain Malnutrition. related to Yellow Fever Disease", "completion": "Globally, maternal and child under-nutrition are underlying causes for 3\u00b75 million deaths, including 35% of the disease burden in children younger than 5 years. Of the 40 countries with a child stunting prevalence of 40% or more, 23 are in Africa. The most vulnerable are children under five and pregnant and lactating women. The poor nutritional status and nutritional intake of pregnant women may contribute to newborns with low birth weight. Programmes elaborated to eradicate malnutrition focus on food security, water and sanitation, promotion of infant and young children feeding practices, micronutrient supplementation programmes, management of severe cases of malnutrition in communities and health facilities, and management of infections mainly diarrhoeal disease. Nutrition surveillance is currently poorly implemented and does not allow for interventions related to prevention and management of malnutrition."}, {"prompt": "Describe Malnutrition. related to Yellow Fever Disease", "completion": "Globally, maternal and child under-nutrition are underlying causes for 3\u00b75 million deaths, including 35% of the disease burden in children younger than 5 years. Of the 40 countries with a child stunting prevalence of 40% or more, 23 are in Africa. The most vulnerable are children under five and pregnant and lactating women. The poor nutritional status and nutritional intake of pregnant women may contribute to newborns with low birth weight. Programmes elaborated to eradicate malnutrition focus on food security, water and sanitation, promotion of infant and young children feeding practices, micronutrient supplementation programmes, management of severe cases of malnutrition in communities and health facilities, and management of infections mainly diarrhoeal disease. Nutrition surveillance is currently poorly implemented and does not allow for interventions related to prevention and management of malnutrition."}, {"prompt": "Elaborate on Malnutrition. related to Yellow Fever Disease", "completion": "Globally, maternal and child under-nutrition are underlying causes for 3\u00b75 million deaths, including 35% of the disease burden in children younger than 5 years. Of the 40 countries with a child stunting prevalence of 40% or more, 23 are in Africa. The most vulnerable are children under five and pregnant and lactating women. The poor nutritional status and nutritional intake of pregnant women may contribute to newborns with low birth weight. Programmes elaborated to eradicate malnutrition focus on food security, water and sanitation, promotion of infant and young children feeding practices, micronutrient supplementation programmes, management of severe cases of malnutrition in communities and health facilities, and management of infections mainly diarrhoeal disease. Nutrition surveillance is currently poorly implemented and does not allow for interventions related to prevention and management of malnutrition."}, {"prompt": "Define Malnutrition. related to Yellow Fever Disease", "completion": "Globally, maternal and child under-nutrition are underlying causes for 3\u00b75 million deaths, including 35% of the disease burden in children younger than 5 years. Of the 40 countries with a child stunting prevalence of 40% or more, 23 are in Africa. The most vulnerable are children under five and pregnant and lactating women. The poor nutritional status and nutritional intake of pregnant women may contribute to newborns with low birth weight. Programmes elaborated to eradicate malnutrition focus on food security, water and sanitation, promotion of infant and young children feeding practices, micronutrient supplementation programmes, management of severe cases of malnutrition in communities and health facilities, and management of infections mainly diarrhoeal disease. Nutrition surveillance is currently poorly implemented and does not allow for interventions related to prevention and management of malnutrition."}, {"prompt": "What is the nature of Malnutrition? related to Yellow Fever Disease", "completion": "Globally, maternal and child under-nutrition are underlying causes for 3\u00b75 million deaths, including 35% of the disease burden in children younger than 5 years. Of the 40 countries with a child stunting prevalence of 40% or more, 23 are in Africa. The most vulnerable are children under five and pregnant and lactating women. The poor nutritional status and nutritional intake of pregnant women may contribute to newborns with low birth weight. Programmes elaborated to eradicate malnutrition focus on food security, water and sanitation, promotion of infant and young children feeding practices, micronutrient supplementation programmes, management of severe cases of malnutrition in communities and health facilities, and management of infections mainly diarrhoeal disease. Nutrition surveillance is currently poorly implemented and does not allow for interventions related to prevention and management of malnutrition."}, {"prompt": "Why is Malnutrition a global health priority? related to Yellow Fever Disease", "completion": "Severe malnutrition may act as a direct cause of death or an indirect cause by increasing dramatically the number of deaths in children suffering from common childhood illnesses such as diarrhea and pneumonia. The burden of child mortality due to severe malnutrition remains largely absent from the international health agenda and few countries, even in high prevalence areas, have specific national policies aimed at addressing it comprehensively."}, {"prompt": "What makes Malnutrition a priority in global health efforts? related to Yellow Fever Disease", "completion": "Severe malnutrition may act as a direct cause of death or an indirect cause by increasing dramatically the number of deaths in children suffering from common childhood illnesses such as diarrhea and pneumonia. The burden of child mortality due to severe malnutrition remains largely absent from the international health agenda and few countries, even in high prevalence areas, have specific national policies aimed at addressing it comprehensively."}, {"prompt": "What are the reasons behind Malnutrition being a global health priority? related to Yellow Fever Disease", "completion": "Severe malnutrition may act as a direct cause of death or an indirect cause by increasing dramatically the number of deaths in children suffering from common childhood illnesses such as diarrhea and pneumonia. The burden of child mortality due to severe malnutrition remains largely absent from the international health agenda and few countries, even in high prevalence areas, have specific national policies aimed at addressing it comprehensively."}, {"prompt": "Who is most vulnerable to Malnutrition? related to Yellow Fever Disease", "completion": "Socio-economic conditions, poor water and sanitation, mothers' nutritional education on how to feed babies and young children, and repeated infections are the main causes of malnutrition."}, {"prompt": "Who are the individuals most susceptible to Malnutrition? related to Yellow Fever Disease", "completion": "Socio-economic conditions, poor water and sanitation, mothers' nutritional education on how to feed babies and young children, and repeated infections are the main causes of malnutrition."}, {"prompt": "What groups of people are at the highest risk of Malnutrition? related to Yellow Fever Disease", "completion": "Socio-economic conditions, poor water and sanitation, mothers' nutritional education on how to feed babies and young children, and repeated infections are the main causes of malnutrition."}, {"prompt": "What are the surveillance objectives for Malnutrition? related to Yellow Fever Disease", "completion": "Early warning and problem identification. Policy-making and planning. Programme management and evaluation. Assess the effectiveness of public health responses that address causes of low birth weight, malnutrition in children, and malnutrition in pregnant women."}, {"prompt": "What is the purpose of surveillance for Malnutrition? related to Yellow Fever Disease", "completion": "Early warning and problem identification. Policy-making and planning. Programme management and evaluation. Assess the effectiveness of public health responses that address causes of low birth weight, malnutrition in children, and malnutrition in pregnant women."}, {"prompt": "What are the main goals of surveillance for Malnutrition? related to Yellow Fever Disease", "completion": "Early warning and problem identification. Policy-making and planning. Programme management and evaluation. Assess the effectiveness of public health responses that address causes of low birth weight, malnutrition in children, and malnutrition in pregnant women."}, {"prompt": "How is a low birth weight newborn defined? related to Yellow Fever Disease", "completion": "Any newborn with a birth weight less than 2500 grams (or 5.5 lbs)."}, {"prompt": "Define a low birth weight newborn. related to Yellow Fever Disease", "completion": "Any newborn with a birth weight less than 2500 grams (or 5.5 lbs)."}, {"prompt": "What is considered a low birth weight newborn? related to Yellow Fever Disease", "completion": "Any newborn with a birth weight less than 2500 grams (or 5.5 lbs)."}, {"prompt": "How is malnutrition in children defined? related to Yellow Fever Disease", "completion": "Children under five who are underweight (indicator: weight for age<-2 ZScore), Children 6 to 59 months with MUAC<11.5 cm (high risk of mortality). Bilateral pitting edema."}, {"prompt": "Define malnutrition in children. related to Yellow Fever Disease", "completion": "Children under five who are underweight (indicator: weight for age<-2 ZScore), Children 6 to 59 months with MUAC<11.5 cm (high risk of mortality). Bilateral pitting edema."}, {"prompt": "What is the definition of malnutrition in children? related to Yellow Fever Disease", "completion": "Children under five who are underweight (indicator: weight for age<-2 ZScore), Children 6 to 59 months with MUAC<11.5 cm (high risk of mortality). Bilateral pitting edema."}, {"prompt": "How is malnutrition in pregnant women defined? related to Yellow Fever Disease", "completion": "Pregnant women giving birth to low birth weight babies (birth weight < 2.5 Kg)."}, {"prompt": "Define malnutrition in pregnant women. related to Yellow Fever Disease", "completion": "Pregnant women giving birth to low birth weight babies (birth weight < 2.5 Kg)."}, {"prompt": "What is the definition of malnutrition in pregnant women? related to Yellow Fever Disease", "completion": "Pregnant women giving birth to low birth weight babies (birth weight < 2.5 Kg)."}, {"prompt": "How should you respond when the alert threshold for Malnutrition in children is reached? related to Yellow Fever Disease", "completion": "If more than 20% of children are underweight, the programme should emphasize on Breastfeeding support, Nutrition education, Supplementation of child and mother, Prevention and treatment of diarrhoea, Prevention and treatment of severe malnutrition, Socio-economic support. If a child with MUAC less than 11.5 cm is detected or presence of bilateral edema is identified, an alert should be raised, further investigation should be conducted, and the child should be referred to a therapeutic feeding programme."}, {"prompt": "How to act when the alert threshold for Malnutrition in children is reached? related to Yellow Fever Disease", "completion": "If more than 20% of children are underweight, the programme should emphasize on Breastfeeding support, Nutrition education, Supplementation of child and mother, Prevention and treatment of diarrhoea, Prevention and treatment of severe malnutrition, Socio-economic support. If a child with MUAC less than 11.5 cm is detected or presence of bilateral edema is identified, an alert should be raised, further investigation should be conducted, and the child should be referred to a therapeutic feeding programme."}, {"prompt": "What should be done when the alert threshold for Malnutrition in children is reached? related to Yellow Fever Disease", "completion": "If more than 20% of children are underweight, the programme should emphasize on Breastfeeding support, Nutrition education, Supplementation of child and mother, Prevention and treatment of diarrhoea, Prevention and treatment of severe malnutrition, Socio-economic support. If a child with MUAC less than 11.5 cm is detected or presence of bilateral edema is identified, an alert should be raised, further investigation should be conducted, and the child should be referred to a therapeutic feeding programme."}, {"prompt": "How should you respond when the alert threshold for Malnutrition in pregnant women is reached? related to Yellow Fever Disease", "completion": "If more or equal than 15% of low birth weight are less than 2.5 Kg, interventions should be targeted for improved antenatal care for women and neonatal care of infants including nutritional care (anti-smoking and anti-alcohol campaigns, nutritional care for women before and during antenatal and during lactating period, malaria prophylaxis, new-born care facilities, etc.) to those at risk of poor pregnancy outcomes and treat newborns to prevent morbidity and death."}, {"prompt": "How to act when the alert threshold for Malnutrition in pregnant women is reached? related to Yellow Fever Disease", "completion": "If more or equal than 15% of low birth weight are less than 2.5 Kg, interventions should be targeted for improved antenatal care for women and neonatal care of infants including nutritional care (anti-smoking and anti-alcohol campaigns, nutritional care for women before and during antenatal and during lactating period, malaria prophylaxis, new-born care facilities, etc.) to those at risk of poor pregnancy outcomes and treat newborns to prevent morbidity and death."}, {"prompt": "What should be done when the alert threshold for Malnutrition in pregnant women is reached? related to Yellow Fever Disease", "completion": "If more or equal than 15% of low birth weight are less than 2.5 Kg, interventions should be targeted for improved antenatal care for women and neonatal care of infants including nutritional care (anti-smoking and anti-alcohol campaigns, nutritional care for women before and during antenatal and during lactating period, malaria prophylaxis, new-born care facilities, etc.) to those at risk of poor pregnancy outcomes and treat newborns to prevent morbidity and death."}, {"prompt": "How should data about a person with Malnutrition be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count monthly/weekly cases and analyze age and gender distribution."}, {"prompt": "How to analyze and interpret data about individuals with Malnutrition? related to Yellow Fever Disease", "completion": "Count monthly/weekly cases and analyze age and gender distribution."}, {"prompt": "What are the methods for analyzing and interpreting data about individuals with Malnutrition? related to Yellow Fever Disease", "completion": "Count monthly/weekly cases and analyze age and gender distribution."}, {"prompt": "How should data about time in the context of Malnutrition be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases monthly to analyze trends and weekly in emergencies."}, {"prompt": "What is the best way to analyze and interpret data over time in the context of Malnutrition? related to Yellow Fever Disease", "completion": "Graph cases monthly to analyze trends and weekly in emergencies."}, {"prompt": "How to analyze and interpret data over time in the context of Malnutrition? related to Yellow Fever Disease", "completion": "Graph cases monthly to analyze trends and weekly in emergencies."}, {"prompt": "How should data about place in the context of Malnutrition be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Identify the most affected villages. Plot location of households/community with cases."}, {"prompt": "What is the appropriate way to analyze and interpret spatial data in the context of Malnutrition? related to Yellow Fever Disease", "completion": "Identify the most affected villages. Plot location of households/community with cases."}, {"prompt": "How to analyze and interpret spatial data in the context of Malnutrition? related to Yellow Fever Disease", "completion": "Identify the most affected villages. Plot location of households/community with cases."}, {"prompt": "How is Malnutrition diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required for malnutrition."}, {"prompt": "What are the laboratory procedures for diagnosing Malnutrition? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required for malnutrition."}, {"prompt": "How to diagnose Malnutrition in the laboratory? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance is not required for malnutrition."}, {"prompt": "What are the references for Malnutrition? related to Yellow Fever Disease", "completion": "1. Maternal and child undernutrition: global and regional exposures and health consequences: Black R.E. et al :The Lancet, Volume 371, Issue 9608, Pages 243 - 260.\n2. Gross R, Webb P, Wasting time for wasted children: severe child undernutrition must be resolved in non-emergency settings. Lancet 2006; 367: 1209-1211.\n3. Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. WHO Technical Report Series, 1995, No 854: 81, 128-130, 198-208.\n4. WHO child growth standards and the identification of severe acute malnutrition in infants and children. A Joint Statement by the World Health Organization and the United Nations Children's Fund."}, {"prompt": "What are the recommended references for Malnutrition? related to Yellow Fever Disease", "completion": "1. Maternal and child undernutrition: global and regional exposures and health consequences: Black R.E. et al :The Lancet, Volume 371, Issue 9608, Pages 243 - 260.\n2. Gross R, Webb P, Wasting time for wasted children: severe child undernutrition must be resolved in non-emergency settings. Lancet 2006; 367: 1209-1211.\n3. Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. WHO Technical Report Series, 1995, No 854: 81, 128-130, 198-208.\n4. WHO child growth standards and the identification of severe acute malnutrition in infants and children. A Joint Statement by the World Health Organization and the United Nations Children's Fund."}, {"prompt": "Explain Malaria. related to Yellow Fever Disease", "completion": "Serious malarial infections are usually due to P. falciparum which may result in severe anaemia and vital organ involvement. Over 95% of the malaria infections in Uganda are due to P. falciparum. Incubation period from the time of being bitten to onset of symptoms is 7 to 30 days. The incubation period may be longer, especially with non- P. falciparum species."}, {"prompt": "Describe Malaria. related to Yellow Fever Disease", "completion": "Serious malarial infections are usually due to P. falciparum which may result in severe anaemia and vital organ involvement. Over 95% of the malaria infections in Uganda are due to P. falciparum. Incubation period from the time of being bitten to onset of symptoms is 7 to 30 days. The incubation period may be longer, especially with non- P. falciparum species."}, {"prompt": "Elaborate on Malaria. related to Yellow Fever Disease", "completion": "Serious malarial infections are usually due to P. falciparum which may result in severe anaemia and vital organ involvement. Over 95% of the malaria infections in Uganda are due to P. falciparum. Incubation period from the time of being bitten to onset of symptoms is 7 to 30 days. The incubation period may be longer, especially with non- P. falciparum species."}, {"prompt": "Define Malaria. related to Yellow Fever Disease", "completion": "Serious malarial infections are usually due to P. falciparum which may result in severe anaemia and vital organ involvement. Over 95% of the malaria infections in Uganda are due to P. falciparum. Incubation period from the time of being bitten to onset of symptoms is 7 to 30 days. The incubation period may be longer, especially with non- P. falciparum species."}, {"prompt": "What is the nature of Malaria? related to Yellow Fever Disease", "completion": "Serious malarial infections are usually due to P. falciparum which may result in severe anaemia and vital organ involvement. Over 95% of the malaria infections in Uganda are due to P. falciparum. Incubation period from the time of being bitten to onset of symptoms is 7 to 30 days. The incubation period may be longer, especially with non- P. falciparum species."}, {"prompt": "How is Malaria transmitted? related to Yellow Fever Disease", "completion": "Malaria is a highly prevalent tropical illness with fever following the bite of infected female Anopheles mosquitoes which transmit a parasite, Plasmodium falciparum, P. ovale, P. vivax, or P. malariae."}, {"prompt": "What are the methods of Malaria transmission? related to Yellow Fever Disease", "completion": "Malaria is a highly prevalent tropical illness with fever following the bite of infected female Anopheles mosquitoes which transmit a parasite, Plasmodium falciparum, P. ovale, P. vivax, or P. malariae."}, {"prompt": "How does Malaria spread? related to Yellow Fever Disease", "completion": "Malaria is a highly prevalent tropical illness with fever following the bite of infected female Anopheles mosquitoes which transmit a parasite, Plasmodium falciparum, P. ovale, P. vivax, or P. malariae."}, {"prompt": "Why is Malaria a global health priority? related to Yellow Fever Disease", "completion": "Malaria is one of the leading causes of illness and death in Uganda. Malaria contributes 30% 0f all outpatients and 10% of the mortality in Uganda. The groups at higher risk of contracting malaria and getting severe disease are pregnant women, children under 5, patients with HIV/AIDS, as well as non-immune migrants, mobile populations and travelers from non-endemic countries."}, {"prompt": "What makes Malaria a priority in global health efforts? related to Yellow Fever Disease", "completion": "Malaria is one of the leading causes of illness and death in Uganda. Malaria contributes 30% 0f all outpatients and 10% of the mortality in Uganda. The groups at higher risk of contracting malaria and getting severe disease are pregnant women, children under 5, patients with HIV/AIDS, as well as non-immune migrants, mobile populations and travelers from non-endemic countries."}, {"prompt": "What are the reasons behind Malaria being a global health priority? related to Yellow Fever Disease", "completion": "Malaria is one of the leading causes of illness and death in Uganda. Malaria contributes 30% 0f all outpatients and 10% of the mortality in Uganda. The groups at higher risk of contracting malaria and getting severe disease are pregnant women, children under 5, patients with HIV/AIDS, as well as non-immune migrants, mobile populations and travelers from non-endemic countries."}, {"prompt": "Who is most vulnerable to Malaria? related to Yellow Fever Disease", "completion": "The groups at higher risk of contracting malaria and getting severe disease are pregnant women, children under 5, patients with HIV/AIDS, as well as non-immune migrants, mobile populations and travelers from non-endemic countries."}, {"prompt": "Who are the individuals most susceptible to Malaria? related to Yellow Fever Disease", "completion": "The groups at higher risk of contracting malaria and getting severe disease are pregnant women, children under 5, patients with HIV/AIDS, as well as non-immune migrants, mobile populations and travelers from non-endemic countries."}, {"prompt": "What groups of people are at the highest risk of Malaria? related to Yellow Fever Disease", "completion": "The groups at higher risk of contracting malaria and getting severe disease are pregnant women, children under 5, patients with HIV/AIDS, as well as non-immune migrants, mobile populations and travelers from non-endemic countries."}, {"prompt": "What are the surveillance objectives for Malaria? related to Yellow Fever Disease", "completion": "Have a system that ensures early warning, forecasting, detection and prompt response to malaria epidemics, especially in areas prone epidemics."}, {"prompt": "What are the goals of Malaria surveillance? related to Yellow Fever Disease", "completion": "Have a system that ensures early warning, forecasting, detection and prompt response to malaria epidemics, especially in areas prone epidemics."}, {"prompt": "What are the surveillance targets for Malaria? related to Yellow Fever Disease", "completion": "Have a system that ensures early warning, forecasting, detection and prompt response to malaria epidemics, especially in areas prone epidemics."}, {"prompt": "What is the standard case definition for uncomplicated Malaria? related to Yellow Fever Disease", "completion": "Any person living in an area at risk of malaria with fever or history of fever within 24 hours; without signs of severe disease (vital organ dysfunction) is diagnosed clinically as malaria."}, {"prompt": "How is uncomplicated Malaria diagnosed? related to Yellow Fever Disease", "completion": "Any person living in an area at risk of malaria with fever or history of fever within 24 hours; without signs of severe disease (vital organ dysfunction) is diagnosed clinically as malaria."}, {"prompt": "What is the standard case definition for confirmed uncomplicated Malaria? related to Yellow Fever Disease", "completion": "Any person with fever or history of fever within 24 hours; and with laboratory confirmation of diagnosis by malaria blood film or other diagnostic test for malaria parasites."}, {"prompt": "How is confirmed uncomplicated Malaria diagnosed? related to Yellow Fever Disease", "completion": "Any person with fever or history of fever within 24 hours; and with laboratory confirmation of diagnosis by malaria blood film or other diagnostic test for malaria parasites."}, {"prompt": "What is the standard case definition for unconfirmed severe Malaria? related to Yellow Fever Disease", "completion": "Any patient living in an area at risk of malaria hospitalized with severe febrile disease with accompanying vital organ dysfunction diagnosed clinically."}, {"prompt": "How is unconfirmed severe Malaria diagnosed? related to Yellow Fever Disease", "completion": "Any patient living in an area at risk of malaria hospitalized with severe febrile disease with accompanying vital organ dysfunction diagnosed clinically."}, {"prompt": "What is the standard case definition for confirmed severe Malaria? related to Yellow Fever Disease", "completion": "Any patient hospitalized with P. falciparum asexual parasitaemia as confirmed by laboratory tests with accompanying symptoms and signs of severe disease (vital organ dysfunction) diagnosed through laboratory."}, {"prompt": "How is confirmed severe Malaria diagnosed? related to Yellow Fever Disease", "completion": "Any patient hospitalized with P. falciparum asexual parasitaemia as confirmed by laboratory tests with accompanying symptoms and signs of severe disease (vital organ dysfunction) diagnosed through laboratory."}, {"prompt": "How should preparedness, forecasting, and early warning for Malaria be approached? related to Yellow Fever Disease", "completion": "This entails use of climatic data, rainfall, humidity or temperature to predict malaria epidemics. Other indicators that are useful include mosquito and larval densities, nutritional status, drug and insecticide resistance, loss of immunity because of a recent reduction in population exposure and human population movements in and out of endemic areas. During this period, ensure adequate stock of malaria diagnostics and drugs for the peak transmission season, LLIN distribution, ensure functionality of health facilities and community health workers providing malaria case management, inform authorities of increased risk, and reactivate epidemic Response Task Forces."}, {"prompt": "What measures should be taken for preparedness and early warning of Malaria? related to Yellow Fever Disease", "completion": "This entails use of climatic data, rainfall, humidity or temperature to predict malaria epidemics. Other indicators that are useful include mosquito and larval densities, nutritional status, drug and insecticide resistance, loss of immunity because of a recent reduction in population exposure and human population movements in and out of endemic areas. During this period, ensure adequate stock of malaria diagnostics and drugs for the peak transmission season, LLIN distribution, ensure functionality of health facilities and community health workers providing malaria case management, inform authorities of increased risk, and reactivate epidemic Response Task Forces."}, {"prompt": "How should you respond when the alert threshold for Malaria is reached? related to Yellow Fever Disease", "completion": "If there is an unusual increase in the number of new malaria cases or deaths as compared to the same period in previous non-epidemic years: Verify the epidemic, report suspected epidemic to the next level, treat with appropriate anti-malarial drugs according to national treatment guidelines, investigate the cause for the increase in new cases, and ensure new cases in children age 2 months up to 5 years are managed according to national treatment guidelines."}, {"prompt": "What steps should be taken when the alert threshold for Malaria is reached? related to Yellow Fever Disease", "completion": "If there is an unusual increase in the number of new malaria cases or deaths as compared to the same period in previous non-epidemic years: Verify the epidemic, report suspected epidemic to the next level, treat with appropriate anti-malarial drugs according to national treatment guidelines, investigate the cause for the increase in new cases, and ensure new cases in children age 2 months up to 5 years are managed according to national treatment guidelines."}, {"prompt": "How should you respond when the action threshold for Malaria is reached? related to Yellow Fever Disease", "completion": "If the number of new cases exceeds the upper limit of cases seen in a previous non-epidemic period in previous years: Evaluate and improve coverage and uptake of prevention strategies such as mosquito nets, Malaria case management, Social Behavioural change and community mobilization, test and treat outreaches, and Indoor Residual spraying for all at risk of malaria."}, {"prompt": "What actions are recommended when the action threshold for Malaria is reached? related to Yellow Fever Disease", "completion": "If the number of new cases exceeds the upper limit of cases seen in a previous non-epidemic period in previous years: Evaluate and improve coverage and uptake of prevention strategies such as mosquito nets, Malaria case management, Social Behavioural change and community mobilization, test and treat outreaches, and Indoor Residual spraying for all at risk of malaria."}, {"prompt": "How should data about a person with Malaria be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Count the number of new malaria cases and deaths by month and analyze age groups and time of onset."}, {"prompt": "What are the methods of analyzing and interpreting data about individuals with Malaria? related to Yellow Fever Disease", "completion": "Count the number of new malaria cases and deaths by month and analyze age groups and time of onset."}, {"prompt": "How should data about time in the context of Malaria be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph the number of cases by month/week. Construct an epidemic curve during epidemics."}, {"prompt": "What are the techniques for analyzing and interpreting data about time in Malaria cases? related to Yellow Fever Disease", "completion": "Graph the number of cases by month/week. Construct an epidemic curve during epidemics."}, {"prompt": "How should data about place in the context of Malaria be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Identify the most affected villages. Plot location of households for new cases and deaths."}, {"prompt": "What are the methods of analyzing and interpreting data about the location of Malaria cases? related to Yellow Fever Disease", "completion": "Identify the most affected villages. Plot location of households for new cases and deaths."}, {"prompt": "How is Malaria diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "For microscopy test, the presence of malarial parasites in blood films for suspected cases. For Malaria Rapid Diagnostic Test, a positive or negative test result is obtained. Blood, usually from a finger-stick sample or other accepted methods for very young children, is used as the specimen."}, {"prompt": "What are the laboratory methods used for diagnosing Malaria? related to Yellow Fever Disease", "completion": "For microscopy test, the presence of malarial parasites in blood films for suspected cases. For Malaria Rapid Diagnostic Test, a positive or negative test result is obtained. Blood, usually from a finger-stick sample or other accepted methods for very young children, is used as the specimen."}, {"prompt": "What are the references for Malaria? related to Yellow Fever Disease", "completion": "1. Malaria epidemics: Detection and control, forecasting and prevention. Geneva. World Health Organization. WHO/MAL/98.1084\n2. Basic Laboratory Methods in Medical Parasitology WHO, Geneva, 1991\n3. \u2018Guidelines for Malaria Epidemic Preparedness and Response\u2019 Ministry of Health, Uganda 2012\n4. \u2018Malaria Surveillance Monitoring and Evaluation: A reference manual\u2019, Geneva, World Health Organization 2018."}, {"prompt": "What are the sources of information on Malaria? related to Yellow Fever Disease", "completion": "1. Malaria epidemics: Detection and control, forecasting and prevention. Geneva. World Health Organization. WHO/MAL/98.1084\n2. Basic Laboratory Methods in Medical Parasitology WHO, Geneva, 1991\n3. \u2018Guidelines for Malaria Epidemic Preparedness and Response\u2019 Ministry of Health, Uganda 2012\n4. \u2018Malaria Surveillance Monitoring and Evaluation: A reference manual\u2019, Geneva, World Health Organization 2018."}, {"prompt": "Explain Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "What is Filariasis? related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "Define Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "Describe Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "What are the characteristics of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "What are the causal agents of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "In Africa, the causal agents are filariae Wuchereria bancrofti, Brugia malayi, and Brugia timori."}, {"prompt": "List the causal agents of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "In Africa, the causal agents are filariae Wuchereria bancrofti, Brugia malayi, and Brugia timori."}, {"prompt": "Which parasites cause Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "In Africa, the causal agents are filariae Wuchereria bancrofti, Brugia malayi, and Brugia timori."}, {"prompt": "Identify the organisms responsible for Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "In Africa, the causal agents are filariae Wuchereria bancrofti, Brugia malayi, and Brugia timori."}, {"prompt": "Describe the clinical presentation of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Filarial infection may be clinically asymptomatic (even in the presence of laboratory evidence of lymphatic and kidney damage); the disease may also present as one or more acute manifestations (fever, local swellings, tropical pulmonary eosinophilia syndrome, lymphangitis)."}, {"prompt": "What are the clinical features of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Filarial infection may be clinically asymptomatic (even in the presence of laboratory evidence of lymphatic and kidney damage); the disease may also present as one or more acute manifestations (fever, local swellings, tropical pulmonary eosinophilia syndrome, lymphangitis)."}, {"prompt": "Explain the clinical manifestations of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Filarial infection may be clinically asymptomatic (even in the presence of laboratory evidence of lymphatic and kidney damage); the disease may also present as one or more acute manifestations (fever, local swellings, tropical pulmonary eosinophilia syndrome, lymphangitis)."}, {"prompt": "What are the chronic complications of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Lymphoedema or elephantiasis of the limbs. Damage to the genital organs (including hydrocoele in men). Damage to the kidney (including chyluria) and lymphatic system."}, {"prompt": "List the long-term complications of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphoedema or elephantiasis of the limbs. Damage to the genital organs (including hydrocoele in men). Damage to the kidney (including chyluria) and lymphatic system."}, {"prompt": "What are the sequelae of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Lymphoedema or elephantiasis of the limbs. Damage to the genital organs (including hydrocoele in men). Damage to the kidney (including chyluria) and lymphatic system."}, {"prompt": "How is Lymphatic Filariasis transmitted? related to Yellow Fever Disease", "completion": "Lymphatic filariasis is transmitted by various species of mosquitoes. These parasitic filarial worms lodge in the human lymphatic system, producing millions of immature microfilariae that circulate in the blood. Microfilariae appear in the peripheral blood after 3 to 6 months for Brugia malayi, 6 to 12 months for Wuchereria bancrofti, often with nocturnal periodicity. When a mosquito thereafter bites the infected person, the microfilariae are picked up and the infection may be transmitted to others after about 2 weeks."}, {"prompt": "How is Lymphatic Filariasis spread? related to Yellow Fever Disease", "completion": "Lymphatic filariasis is transmitted by various species of mosquitoes. These parasitic filarial worms lodge in the human lymphatic system, producing millions of immature microfilariae that circulate in the blood. Microfilariae appear in the peripheral blood after 3 to 6 months for Brugia malayi, 6 to 12 months for Wuchereria bancrofti, often with nocturnal periodicity. When a mosquito thereafter bites the infected person, the microfilariae are picked up and the infection may be transmitted to others after about 2 weeks."}, {"prompt": "Explain the mode of transmission for Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is transmitted by various species of mosquitoes. These parasitic filarial worms lodge in the human lymphatic system, producing millions of immature microfilariae that circulate in the blood. Microfilariae appear in the peripheral blood after 3 to 6 months for Brugia malayi, 6 to 12 months for Wuchereria bancrofti, often with nocturnal periodicity. When a mosquito thereafter bites the infected person, the microfilariae are picked up and the infection may be transmitted to others after about 2 weeks."}, {"prompt": "What are the surveillance goals for Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "The goals include observing national trends towards the leprosy elimination target, reducing transmission below a threshold where new infection ceases, and treatment of the problems associated with disability control and prevention. Surveillance options depend on the local situation and can include routine monthly reporting, sentinel population surveys, or active case-finding."}, {"prompt": "What are the objectives of Lymphatic Filariasis surveillance? related to Yellow Fever Disease", "completion": "The goals include observing national trends towards the leprosy elimination target, reducing transmission below a threshold where new infection ceases, and treatment of the problems associated with disability control and prevention. Surveillance options depend on the local situation and can include routine monthly reporting, sentinel population surveys, or active case-finding."}, {"prompt": "How is Lymphatic Filariasis surveillance carried out? related to Yellow Fever Disease", "completion": "The goals include observing national trends towards the leprosy elimination target, reducing transmission below a threshold where new infection ceases, and treatment of the problems associated with disability control and prevention. Surveillance options depend on the local situation and can include routine monthly reporting, sentinel population surveys, or active case-finding."}, {"prompt": "What is the standard case definition for a suspected case of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "A resident of an endemic area with a clinical sign of hydrocoele or lymphoedema for which other causes have been excluded."}, {"prompt": "Describe the case definition for suspected Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "A resident of an endemic area with a clinical sign of hydrocoele or lymphoedema for which other causes have been excluded."}, {"prompt": "What criteria are used to identify suspected Lymphatic Filariasis cases? related to Yellow Fever Disease", "completion": "A resident of an endemic area with a clinical sign of hydrocoele or lymphoedema for which other causes have been excluded."}, {"prompt": "How is a suspected case of Lymphatic Filariasis defined? related to Yellow Fever Disease", "completion": "A resident of an endemic area with a clinical sign of hydrocoele or lymphoedema for which other causes have been excluded."}, {"prompt": "What is the standard case definition for a confirmed case of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "A person with a positive laboratory diagnosis of microfilaremia in a blood smear, filarial antigenaemia, or a positive ultrasound test."}, {"prompt": "Describe the criteria for confirming Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "A person with a positive laboratory diagnosis of microfilaremia in a blood smear, filarial antigenaemia, or a positive ultrasound test."}, {"prompt": "How is a confirmed case of Lymphatic Filariasis diagnosed? related to Yellow Fever Disease", "completion": "A person with a positive laboratory diagnosis of microfilaremia in a blood smear, filarial antigenaemia, or a positive ultrasound test."}, {"prompt": "What are the methods used to confirm Lymphatic Filariasis cases? related to Yellow Fever Disease", "completion": "A person with a positive laboratory diagnosis of microfilaremia in a blood smear, filarial antigenaemia, or a positive ultrasound test."}, {"prompt": "How should you respond when the alert threshold for Lymphatic Filariasis is reached? related to Yellow Fever Disease", "completion": "Confirm community prevalence of infection by conducting surveys."}, {"prompt": "What actions should be taken upon reaching the Lymphatic Filariasis alert threshold? related to Yellow Fever Disease", "completion": "Confirm community prevalence of infection by conducting surveys."}, {"prompt": "What should be done when the Lymphatic Filariasis alert threshold is met? related to Yellow Fever Disease", "completion": "Confirm community prevalence of infection by conducting surveys."}, {"prompt": "How should the Lymphatic Filariasis alert threshold response be managed? related to Yellow Fever Disease", "completion": "Confirm community prevalence of infection by conducting surveys."}, {"prompt": "What actions should be taken if there's an unusual increase in Lymphatic Filariasis cases? related to Yellow Fever Disease", "completion": "For affected body parts, hygiene measures such as washing, raising the affected limb, exercising, nail care, and using antiseptic can decrease the risk of adenolymphangitis. Treatment for filarial carriers should follow the regimen recommended by the country. In areas with concurrent onchocerciasis, the strategy for control is based on anti-parasitic measures. To interrupt transmission, the entire at-risk population must be given a yearly, 1-dose regimen of 400 mg of albendazole + ivermectin 150 micrograms per kg of body weight for 4-6 years. In areas with no concurrent onchocerciasis, the entire at-risk population must be given a yearly, 1-dose regimen of Diethylcarbamazine 6 milligrams per kg of body weight + albendazole 400 mg once a year, or Diethylcarbamazine fortified salt for daily use for at least 6-12 months. In areas with concurrent loiasis, mass interventions are not systematically advised due to the risk of severe adverse reactions in patients with high-density Loa infections."}, {"prompt": "What measures should be taken for managing Lymphatic Filariasis cases? related to Yellow Fever Disease", "completion": "For affected body parts, hygiene measures such as washing, raising the affected limb, exercising, nail care, and using antiseptic can decrease the risk of adenolymphangitis. Treatment for filarial carriers should follow the regimen recommended by the country. In areas with concurrent onchocerciasis, the strategy for control is based on anti-parasitic measures. To interrupt transmission, the entire at-risk population must be given a yearly, 1-dose regimen of 400 mg of albendazole + ivermectin 150 micrograms per kg of body weight for 4-6 years. In areas with no concurrent onchocerciasis, the entire at-risk population must be given a yearly, 1-dose regimen of Diethylcarbamazine 6 milligrams per kg of body weight + albendazole 400 mg once a year, or Diethylcarbamazine fortified salt for daily use for at least 6-12 months. In areas with concurrent loiasis, mass interventions are not systematically advised due to the risk of severe adverse reactions in patients with high-density Loa infections."}, {"prompt": "What is the management approach for Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "For affected body parts, hygiene measures such as washing, raising the affected limb, exercising, nail care, and using antiseptic can decrease the risk of adenolymphangitis. Treatment for filarial carriers should follow the regimen recommended by the country. In areas with concurrent onchocerciasis, the strategy for control is based on anti-parasitic measures. To interrupt transmission, the entire at-risk population must be given a yearly, 1-dose regimen of 400 mg of albendazole + ivermectin 150 micrograms per kg of body weight for 4-6 years. In areas with no concurrent onchocerciasis, the entire at-risk population must be given a yearly, 1-dose regimen of Diethylcarbamazine 6 milligrams per kg of body weight + albendazole 400 mg once a year, or Diethylcarbamazine fortified salt for daily use for at least 6-12 months. In areas with concurrent loiasis, mass interventions are not systematically advised due to the risk of severe adverse reactions in patients with high-density Loa infections."}, {"prompt": "What are the recommended actions for Lymphatic Filariasis case management? related to Yellow Fever Disease", "completion": "For affected body parts, hygiene measures such as washing, raising the affected limb, exercising, nail care, and using antiseptic can decrease the risk of adenolymphangitis. Treatment for filarial carriers should follow the regimen recommended by the country. In areas with concurrent onchocerciasis, the strategy for control is based on anti-parasitic measures. To interrupt transmission, the entire at-risk population must be given a yearly, 1-dose regimen of 400 mg of albendazole + ivermectin 150 micrograms per kg of body weight for 4-6 years. In areas with no concurrent onchocerciasis, the entire at-risk population must be given a yearly, 1-dose regimen of Diethylcarbamazine 6 milligrams per kg of body weight + albendazole 400 mg once a year, or Diethylcarbamazine fortified salt for daily use for at least 6-12 months. In areas with concurrent loiasis, mass interventions are not systematically advised due to the risk of severe adverse reactions in patients with high-density Loa infections."}, {"prompt": "How should data about Lymphatic Filariasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Map the distribution of Lymphatic Filariasis and identify implementation units that will require mass drug administration. Analyze the drug coverage in implementation units. Assess the decline of parasitological indices microfilaremia before starting MDA and after at least four rounds of MDA till the criteria of less than 1% microfilaraemia in the population and less than 0.1% antigenaemia in school entry children is achieved."}, {"prompt": "What is the analysis process for Lymphatic Filariasis data? related to Yellow Fever Disease", "completion": "Map the distribution of Lymphatic Filariasis and identify implementation units that will require mass drug administration. Analyze the drug coverage in implementation units. Assess the decline of parasitological indices microfilaremia before starting MDA and after at least four rounds of MDA till the criteria of less than 1% microfilaraemia in the population and less than 0.1% antigenaemia in school entry children is achieved."}, {"prompt": "How is data about Lymphatic Filariasis interpreted? related to Yellow Fever Disease", "completion": "Map the distribution of Lymphatic Filariasis and identify implementation units that will require mass drug administration. Analyze the drug coverage in implementation units. Assess the decline of parasitological indices microfilaremia before starting MDA and after at least four rounds of MDA till the criteria of less than 1% microfilaraemia in the population and less than 0.1% antigenaemia in school entry children is achieved."}, {"prompt": "What are the references for Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "1. WHO. Monitoring and epidemiological assessment of the programme to eliminate lymphatic filariasis at the implementation unit level. WHO/CDS/CPE/CEE/2005.50.\n2. WHO. Lymphatic filariasis. WHO/CDS/CPE/SMT/2001.7.\n3. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.10 (Parts 1 &2).\n4. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is co-endemic). WHO/CDS/CPE/CEE/2000.11 (Parts 1 & 2).\n5. WHO. The programme to eliminate lymphatic filariasis \u2013 essential elements for medical personnel (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.12.\n6. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n7. WHO. Preparing and implementing a national plan to eliminate filariasis (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.15.\n8. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n9. Webpage: www.who.int/lymphatic filariasis."}, {"prompt": "What are the sources used for Lymphatic Filariasis references? related to Yellow Fever Disease", "completion": "1. WHO. Monitoring and epidemiological assessment of the programme to eliminate lymphatic filariasis at the implementation unit level. WHO/CDS/CPE/CEE/2005.50.\n2. WHO. Lymphatic filariasis. WHO/CDS/CPE/SMT/2001.7.\n3. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.10 (Parts 1 &2).\n4. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is co-endemic). WHO/CDS/CPE/CEE/2000.11 (Parts 1 & 2).\n5. WHO. The programme to eliminate lymphatic filariasis \u2013 essential elements for medical personnel (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.12.\n6. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n7. WHO. Preparing and implementing a national plan to eliminate filariasis (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.15.\n8. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n9. Webpage: www.who.int/lymphatic filariasis."}, {"prompt": "Explain Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "Describe Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "Elaborate on Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "Define Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "What is the nature of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Lymphatic filariasis is the second leading cause of permanent and long-term disability worldwide. It affects over 120 million persons in 80 countries, and over 40 million persons are seriously incapacitated by the disease; 20% of the world population is at risk of infection. Of those infected, roughly 1/3 are in India, 1/3 in Africa, and the rest in the Americas, Asia, and the Pacific. In 1997, resolution WHA50.29 called for the elimination of lymphatic filariasis as a global public health problem. The strategy adopted is based on reducing transmission below a threshold where new infection ceases to occur and treatment of the problems associated with disability control and prevention."}, {"prompt": "What are the causal agents of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "In Africa, the causal agents are filariae Wuchereria bancrofti, Brugia malayi, and Brugia timori."}, {"prompt": "What organisms cause Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "In Africa, the causal agents are filariae Wuchereria bancrofti, Brugia malayi, and Brugia timori."}, {"prompt": "List the causal agents of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "In Africa, the causal agents are filariae Wuchereria bancrofti, Brugia malayi, and Brugia timori."}, {"prompt": "Identify the pathogens responsible for Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "In Africa, the causal agents are filariae Wuchereria bancrofti, Brugia malayi, and Brugia timori."}, {"prompt": "Describe the clinical presentation of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Filarial infection may be clinically asymptomatic (even in the presence of laboratory evidence of lymphatic and kidney damage); the disease may also present as one or more acute manifestations (fever, local swellings, tropical pulmonary eosinophilia syndrome, lymphangitis)."}, {"prompt": "What are the common clinical manifestations of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Filarial infection may be clinically asymptomatic (even in the presence of laboratory evidence of lymphatic and kidney damage); the disease may also present as one or more acute manifestations (fever, local swellings, tropical pulmonary eosinophilia syndrome, lymphangitis)."}, {"prompt": "Explain the clinical presentation of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Filarial infection may be clinically asymptomatic (even in the presence of laboratory evidence of lymphatic and kidney damage); the disease may also present as one or more acute manifestations (fever, local swellings, tropical pulmonary eosinophilia syndrome, lymphangitis)."}, {"prompt": "What are the long-term clinical effects of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Filarial infection may be clinically asymptomatic (even in the presence of laboratory evidence of lymphatic and kidney damage); the disease may also present as one or more acute manifestations (fever, local swellings, tropical pulmonary eosinophilia syndrome, lymphangitis)."}, {"prompt": "What are the chronic complications of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Lymphoedema or elephantiasis of the limbs. Damage to the genital organs (including hydrocoele in men). Damage to the kidney (including chyluria) and lymphatic system."}, {"prompt": "List the long-term complications of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphoedema or elephantiasis of the limbs. Damage to the genital organs (including hydrocoele in men). Damage to the kidney (including chyluria) and lymphatic system."}, {"prompt": "Enumerate the chronic complications of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphoedema or elephantiasis of the limbs. Damage to the genital organs (including hydrocoele in men). Damage to the kidney (including chyluria) and lymphatic system."}, {"prompt": "How is Lymphatic Filariasis transmitted? related to Yellow Fever Disease", "completion": "Lymphatic filariasis is transmitted by various species of mosquitoes. These parasitic filarial worms lodge in the human lymphatic system, producing millions of immature microfilariae that circulate in the blood. Microfilariae appear in the peripheral blood after 3 to 6 months for Brugia malayi, 6 to 12 months for Wuchereria bancrofti, often with nocturnal periodicity. When a mosquito thereafter bites the infected person, the microfilariae are picked up and the infection may be transmitted to others after about 2 weeks."}, {"prompt": "What is the mode of transmission of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Lymphatic filariasis is transmitted by various species of mosquitoes. These parasitic filarial worms lodge in the human lymphatic system, producing millions of immature microfilariae that circulate in the blood. Microfilariae appear in the peripheral blood after 3 to 6 months for Brugia malayi, 6 to 12 months for Wuchereria bancrofti, often with nocturnal periodicity. When a mosquito thereafter bites the infected person, the microfilariae are picked up and the infection may be transmitted to others after about 2 weeks."}, {"prompt": "How does Lymphatic Filariasis spread? related to Yellow Fever Disease", "completion": "Lymphatic filariasis is transmitted by various species of mosquitoes. These parasitic filarial worms lodge in the human lymphatic system, producing millions of immature microfilariae that circulate in the blood. Microfilariae appear in the peripheral blood after 3 to 6 months for Brugia malayi, 6 to 12 months for Wuchereria bancrofti, often with nocturnal periodicity. When a mosquito thereafter bites the infected person, the microfilariae are picked up and the infection may be transmitted to others after about 2 weeks."}, {"prompt": "List the modes of transmission of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Lymphatic filariasis is transmitted by various species of mosquitoes. These parasitic filarial worms lodge in the human lymphatic system, producing millions of immature microfilariae that circulate in the blood. Microfilariae appear in the peripheral blood after 3 to 6 months for Brugia malayi, 6 to 12 months for Wuchereria bancrofti, often with nocturnal periodicity. When a mosquito thereafter bites the infected person, the microfilariae are picked up and the infection may be transmitted to others after about 2 weeks."}, {"prompt": "What are the surveillance goals for Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "The goals include observing national trends towards the leprosy elimination target, reducing transmission below a threshold where new infection ceases, and treatment of the problems associated with disability control and prevention. Surveillance options depend on the local situation and can include routine monthly reporting, sentinel population surveys, or active case-finding."}, {"prompt": "What are the objectives of Lymphatic Filariasis surveillance? related to Yellow Fever Disease", "completion": "The goals include observing national trends towards the leprosy elimination target, reducing transmission below a threshold where new infection ceases, and treatment of the problems associated with disability control and prevention. Surveillance options depend on the local situation and can include routine monthly reporting, sentinel population surveys, or active case-finding."}, {"prompt": "Elaborate on the surveillance goals for Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "The goals include observing national trends towards the leprosy elimination target, reducing transmission below a threshold where new infection ceases, and treatment of the problems associated with disability control and prevention. Surveillance options depend on the local situation and can include routine monthly reporting, sentinel population surveys, or active case-finding."}, {"prompt": "What are the targets of Lymphatic Filariasis surveillance? related to Yellow Fever Disease", "completion": "The goals include observing national trends towards the leprosy elimination target, reducing transmission below a threshold where new infection ceases, and treatment of the problems associated with disability control and prevention. Surveillance options depend on the local situation and can include routine monthly reporting, sentinel population surveys, or active case-finding."}, {"prompt": "What is the standard case definition for a suspected case of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "A resident of an endemic area with a clinical sign of hydrocoele or lymphoedema for which other causes have been excluded."}, {"prompt": "How is a suspected case of Lymphatic Filariasis defined? related to Yellow Fever Disease", "completion": "A resident of an endemic area with a clinical sign of hydrocoele or lymphoedema for which other causes have been excluded."}, {"prompt": "Define the standard case definition for a suspected case of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "A resident of an endemic area with a clinical sign of hydrocoele or lymphoedema for which other causes have been excluded."}, {"prompt": "What are the criteria for a suspected case of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "A resident of an endemic area with a clinical sign of hydrocoele or lymphoedema for which other causes have been excluded."}, {"prompt": "What is the standard case definition for a confirmed case of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "A person with a positive laboratory diagnosis of microfilaremia in a blood smear, filarial antigenaemia, or a positive ultrasound test."}, {"prompt": "How is a confirmed case of Lymphatic Filariasis defined? related to Yellow Fever Disease", "completion": "A person with a positive laboratory diagnosis of microfilaremia in a blood smear, filarial antigenaemia, or a positive ultrasound test."}, {"prompt": "Define the standard case definition for a confirmed case of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "A person with a positive laboratory diagnosis of microfilaremia in a blood smear, filarial antigenaemia, or a positive ultrasound test."}, {"prompt": "What are the criteria for a confirmed case of Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "A person with a positive laboratory diagnosis of microfilaremia in a blood smear, filarial antigenaemia, or a positive ultrasound test."}, {"prompt": "How should you respond when the alert threshold for Lymphatic Filariasis is reached? related to Yellow Fever Disease", "completion": "Confirm community prevalence of infection by conducting surveys."}, {"prompt": "What actions should be taken when the alert threshold for Lymphatic Filariasis is reached? related to Yellow Fever Disease", "completion": "Confirm community prevalence of infection by conducting surveys."}, {"prompt": "What should you do when the alert threshold for Lymphatic Filariasis is reached? related to Yellow Fever Disease", "completion": "Confirm community prevalence of infection by conducting surveys."}, {"prompt": "What is the appropriate response when the alert threshold for Lymphatic Filariasis is reached? related to Yellow Fever Disease", "completion": "Confirm community prevalence of infection by conducting surveys."}, {"prompt": "How should case management for Lymphatic Filariasis be approached? related to Yellow Fever Disease", "completion": "For affected body parts, hygiene measures such as washing, raising the affected limb, exercising, nail care, and using antiseptic can decrease the risk of adenolymphangitis. Treatment for filarial carriers should follow the regimen recommended by the country. In areas with concurrent onchocerciasis, the strategy for control is based on anti-parasitic measures. To interrupt transmission, the entire at-risk population must be given a yearly, 1-dose regimen of 400 mg of albendazole + ivermectin 150 micrograms per kg of body weight for 4-6 years. In areas with no concurrent onchocerciasis, the entire at-risk population must be given a yearly, 1-dose regimen of Diethylcarbamazine 6 milligrams per kg of body weight + albendazole 400 mg once a year, or Diethylcarbamazine fortified salt for daily use for at least 6-12 months. In areas with concurrent loiasis, mass interventions are not systematically advised due to the risk of severe adverse reactions in patients with high-density Loa infections."}, {"prompt": "How should the management of Lymphatic Filariasis cases be handled? related to Yellow Fever Disease", "completion": "For affected body parts, hygiene measures such as washing, raising the affected limb, exercising, nail care, and using antiseptic can decrease the risk of adenolymphangitis. Treatment for filarial carriers should follow the regimen recommended by the country. In areas with concurrent onchocerciasis, the strategy for control is based on anti-parasitic measures. To interrupt transmission, the entire at-risk population must be given a yearly, 1-dose regimen of 400 mg of albendazole + ivermectin 150 micrograms per kg of body weight for 4-6 years. In areas with no concurrent onchocerciasis, the entire at-risk population must be given a yearly, 1-dose regimen of Diethylcarbamazine 6 milligrams per kg of body weight + albendazole 400 mg once a year, or Diethylcarbamazine fortified salt for daily use for at least 6-12 months. In areas with concurrent loiasis, mass interventions are not systematically advised due to the risk of severe adverse reactions in patients with high-density Loa infections."}, {"prompt": "How should Lymphatic Filariasis cases be managed? related to Yellow Fever Disease", "completion": "For affected body parts, hygiene measures such as washing, raising the affected limb, exercising, nail care, and using antiseptic can decrease the risk of adenolymphangitis. Treatment for filarial carriers should follow the regimen recommended by the country. In areas with concurrent onchocerciasis, the strategy for control is based on anti-parasitic measures. To interrupt transmission, the entire at-risk population must be given a yearly, 1-dose regimen of 400 mg of albendazole + ivermectin 150 micrograms per kg of body weight for 4-6 years. In areas with no concurrent onchocerciasis, the entire at-risk population must be given a yearly, 1-dose regimen of Diethylcarbamazine 6 milligrams per kg of body weight + albendazole 400 mg once a year, or Diethylcarbamazine fortified salt for daily use for at least 6-12 months. In areas with concurrent loiasis, mass interventions are not systematically advised due to the risk of severe adverse reactions in patients with high-density Loa infections."}, {"prompt": "What is the appropriate approach to case management for Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "For affected body parts, hygiene measures such as washing, raising the affected limb, exercising, nail care, and using antiseptic can decrease the risk of adenolymphangitis. Treatment for filarial carriers should follow the regimen recommended by the country. In areas with concurrent onchocerciasis, the strategy for control is based on anti-parasitic measures. To interrupt transmission, the entire at-risk population must be given a yearly, 1-dose regimen of 400 mg of albendazole + ivermectin 150 micrograms per kg of body weight for 4-6 years. In areas with no concurrent onchocerciasis, the entire at-risk population must be given a yearly, 1-dose regimen of Diethylcarbamazine 6 milligrams per kg of body weight + albendazole 400 mg once a year, or Diethylcarbamazine fortified salt for daily use for at least 6-12 months. In areas with concurrent loiasis, mass interventions are not systematically advised due to the risk of severe adverse reactions in patients with high-density Loa infections."}, {"prompt": "How should data about Lymphatic Filariasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Map the distribution of Lymphatic Filariasis and identify implementation units that will require mass drug administration. Analyze the drug coverage in implementation units. Assess the decline of parasitological indices microfilaremia before starting MDA and after at least four rounds of MDA till the criteria of less than 1% microfilaraemia in the population and less than 0.1% antigenaemia in school entry children is achieved."}, {"prompt": "What are the methods for data analysis and interpretation in Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Map the distribution of Lymphatic Filariasis and identify implementation units that will require mass drug administration. Analyze the drug coverage in implementation units. Assess the decline of parasitological indices microfilaremia before starting MDA and after at least four rounds of MDA till the criteria of less than 1% microfilaraemia in the population and less than 0.1% antigenaemia in school entry children is achieved."}, {"prompt": "Describe the data analysis and interpretation for Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Map the distribution of Lymphatic Filariasis and identify implementation units that will require mass drug administration. Analyze the drug coverage in implementation units. Assess the decline of parasitological indices microfilaremia before starting MDA and after at least four rounds of MDA till the criteria of less than 1% microfilaraemia in the population and less than 0.1% antigenaemia in school entry children is achieved."}, {"prompt": "What are the steps for data analysis and interpretation in Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Map the distribution of Lymphatic Filariasis and identify implementation units that will require mass drug administration. Analyze the drug coverage in implementation units. Assess the decline of parasitological indices microfilaremia before starting MDA and after at least four rounds of MDA till the criteria of less than 1% microfilaraemia in the population and less than 0.1% antigenaemia in school entry children is achieved."}, {"prompt": "How is Lymphatic Filariasis diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Diagnosis can be done using a night blood smear, and a filarial antigen test. A positive test occurs when microfilariae of W.bancrofti is seen under the microscope or when filarial antigen is detected."}, {"prompt": "What are the diagnostic methods for Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "Diagnosis can be done using a night blood smear, and a filarial antigen test. A positive test occurs when microfilariae of W.bancrofti is seen under the microscope or when filarial antigen is detected."}, {"prompt": "Describe the laboratory diagnosis of Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "Diagnosis can be done using a night blood smear, and a filarial antigen test. A positive test occurs when microfilariae of W.bancrofti is seen under the microscope or when filarial antigen is detected."}, {"prompt": "How is Lymphatic Filariasis confirmed through laboratory tests? related to Yellow Fever Disease", "completion": "Diagnosis can be done using a night blood smear, and a filarial antigen test. A positive test occurs when microfilariae of W.bancrofti is seen under the microscope or when filarial antigen is detected."}, {"prompt": "What are the references for Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "1. WHO. Monitoring and epidemiological assessment of the programme to eliminate lymphatic filariasis at the implementation unit level. WHO/CDS/CPE/CEE/2005.50.\n2. WHO. Lymphatic filariasis. WHO/CDS/CPE/SMT/2001.7.\n3. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.10 (Parts 1 &2).\n4. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is co-endemic). WHO/CDS/CPE/CEE/2000.11 (Parts 1 & 2).\n5. WHO. The programme to eliminate lymphatic filariasis \u2013 essential elements for medical personnel (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.12.\n6. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n7. WHO. Preparing and implementing a national plan to eliminate filariasis (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.15.\n8. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n9. Webpage: www.who.int/lymphatic filariasis."}, {"prompt": "Where can I find references for Lymphatic Filariasis? related to Yellow Fever Disease", "completion": "1. WHO. Monitoring and epidemiological assessment of the programme to eliminate lymphatic filariasis at the implementation unit level. WHO/CDS/CPE/CEE/2005.50.\n2. WHO. Lymphatic filariasis. WHO/CDS/CPE/SMT/2001.7.\n3. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.10 (Parts 1 &2).\n4. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is co-endemic). WHO/CDS/CPE/CEE/2000.11 (Parts 1 & 2).\n5. WHO. The programme to eliminate lymphatic filariasis \u2013 essential elements for medical personnel (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.12.\n6. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n7. WHO. Preparing and implementing a national plan to eliminate filariasis (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.15.\n8. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n9. Webpage: www.who.int/lymphatic filariasis."}, {"prompt": "Provide the references for Lymphatic Filariasis. related to Yellow Fever Disease", "completion": "1. WHO. Monitoring and epidemiological assessment of the programme to eliminate lymphatic filariasis at the implementation unit level. WHO/CDS/CPE/CEE/2005.50.\n2. WHO. Lymphatic filariasis. WHO/CDS/CPE/SMT/2001.7.\n3. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.10 (Parts 1 &2).\n4. WHO. Training module on lymphatic filariasis for drug distributors (in countries where onchocerciasis is co-endemic). WHO/CDS/CPE/CEE/2000.11 (Parts 1 & 2).\n5. WHO. The programme to eliminate lymphatic filariasis \u2013 essential elements for medical personnel (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.12.\n6. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n7. WHO. Preparing and implementing a national plan to eliminate filariasis (in countries where onchocerciasis is not co-endemic). WHO/CDS/CPE/CEE/2000.15.\n8. WHO. The programme to eliminate lymphatic filariasis (in onchocerciasis co-endemic countries). WHO/CDS/CPE/CEE/2000.16.\n9. Webpage: www.who.int/lymphatic filariasis."}, {"prompt": "Explain Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Crimean-Congo haemorrhagic fever (CCHF) belongs to the Bunyaviridae virus family and Lassa fever belongs to the Arenaviridae virus family. The animal reservoir of the Lassa virus is a rodent of the genus Mastomys. Mastomys infected with Lassa virus do not become ill but shed the virus in their excreta (urine and faeces) and humans usually become infected through aerosol or direct contact with excreta of infected rodents. Lassa fever can also be spread between humans through direct contact with the blood, pharyngeal secretions, urine, faeces or other body secretions of an infected person. Person-to-person transmission of both CCHF and Lassa fever has occurred in health care settings after exposure to blood and secretions of infected patients. The incubation period for CCHF following a tick bite is usually 1-3 days (max 9 days) and following contact with blood or tissues is usually 5-6 days (max 13 days). The incubation period for Lassa fever ranges from 6-21 days. The onset of symptoms among CCHF patients is sudden with fever, myalgia and other signs and symptoms. The reported case fatality ratio for CCHF is between 3% and 30%. About 80% of human Lassa fever infections are mild or asymptomatic; the remaining cases have severe multi-system disease. The onset of disease in symptomatic patients is usually gradual starting with fever, general weakness and malaise. Lassa fever is difficult to distinguish from many other diseases which cause fever, including malaria, shigellosis, typhoid fever, yellow fever and other VHFs. The overall case fatality ratio is 1-15% among hospitalized patients."}, {"prompt": "Describe Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Crimean-Congo haemorrhagic fever (CCHF) belongs to the Bunyaviridae virus family and Lassa fever belongs to the Arenaviridae virus family. The animal reservoir of the Lassa virus is a rodent of the genus Mastomys. Mastomys infected with Lassa virus do not become ill but shed the virus in their excreta (urine and faeces) and humans usually become infected through aerosol or direct contact with excreta of infected rodents. Lassa fever can also be spread between humans through direct contact with the blood, pharyngeal secretions, urine, faeces or other body secretions of an infected person. Person-to-person transmission of both CCHF and Lassa fever has occurred in health care settings after exposure to blood and secretions of infected patients. The incubation period for CCHF following a tick bite is usually 1-3 days (max 9 days) and following contact with blood or tissues is usually 5-6 days (max 13 days). The incubation period for Lassa fever ranges from 6-21 days. The onset of symptoms among CCHF patients is sudden with fever, myalgia and other signs and symptoms. The reported case fatality ratio for CCHF is between 3% and 30%. About 80% of human Lassa fever infections are mild or asymptomatic; the remaining cases have severe multi-system disease. The onset of disease in symptomatic patients is usually gradual starting with fever, general weakness and malaise. Lassa fever is difficult to distinguish from many other diseases which cause fever, including malaria, shigellosis, typhoid fever, yellow fever and other VHFs. The overall case fatality ratio is 1-15% among hospitalized patients."}, {"prompt": "Elaborate on Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Crimean-Congo haemorrhagic fever (CCHF) belongs to the Bunyaviridae virus family and Lassa fever belongs to the Arenaviridae virus family. The animal reservoir of the Lassa virus is a rodent of the genus Mastomys. Mastomys infected with Lassa virus do not become ill but shed the virus in their excreta (urine and faeces) and humans usually become infected through aerosol or direct contact with excreta of infected rodents. Lassa fever can also be spread between humans through direct contact with the blood, pharyngeal secretions, urine, faeces or other body secretions of an infected person. Person-to-person transmission of both CCHF and Lassa fever has occurred in health care settings after exposure to blood and secretions of infected patients. The incubation period for CCHF following a tick bite is usually 1-3 days (max 9 days) and following contact with blood or tissues is usually 5-6 days (max 13 days). The incubation period for Lassa fever ranges from 6-21 days. The onset of symptoms among CCHF patients is sudden with fever, myalgia and other signs and symptoms. The reported case fatality ratio for CCHF is between 3% and 30%. About 80% of human Lassa fever infections are mild or asymptomatic; the remaining cases have severe multi-system disease. The onset of disease in symptomatic patients is usually gradual starting with fever, general weakness and malaise. Lassa fever is difficult to distinguish from many other diseases which cause fever, including malaria, shigellosis, typhoid fever, yellow fever and other VHFs. The overall case fatality ratio is 1-15% among hospitalized patients."}, {"prompt": "Define Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Crimean-Congo haemorrhagic fever (CCHF) belongs to the Bunyaviridae virus family and Lassa fever belongs to the Arenaviridae virus family. The animal reservoir of the Lassa virus is a rodent of the genus Mastomys. Mastomys infected with Lassa virus do not become ill but shed the virus in their excreta (urine and faeces) and humans usually become infected through aerosol or direct contact with excreta of infected rodents. Lassa fever can also be spread between humans through direct contact with the blood, pharyngeal secretions, urine, faeces or other body secretions of an infected person. Person-to-person transmission of both CCHF and Lassa fever has occurred in health care settings after exposure to blood and secretions of infected patients. The incubation period for CCHF following a tick bite is usually 1-3 days (max 9 days) and following contact with blood or tissues is usually 5-6 days (max 13 days). The incubation period for Lassa fever ranges from 6-21 days. The onset of symptoms among CCHF patients is sudden with fever, myalgia and other signs and symptoms. The reported case fatality ratio for CCHF is between 3% and 30%. About 80% of human Lassa fever infections are mild or asymptomatic; the remaining cases have severe multi-system disease. The onset of disease in symptomatic patients is usually gradual starting with fever, general weakness and malaise. Lassa fever is difficult to distinguish from many other diseases which cause fever, including malaria, shigellosis, typhoid fever, yellow fever and other VHFs. The overall case fatality ratio is 1-15% among hospitalized patients."}, {"prompt": "Provide an overview of Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Crimean-Congo haemorrhagic fever (CCHF) belongs to the Bunyaviridae virus family and Lassa fever belongs to the Arenaviridae virus family. The animal reservoir of the Lassa virus is a rodent of the genus Mastomys. Mastomys infected with Lassa virus do not become ill but shed the virus in their excreta (urine and faeces) and humans usually become infected through aerosol or direct contact with excreta of infected rodents. Lassa fever can also be spread between humans through direct contact with the blood, pharyngeal secretions, urine, faeces or other body secretions of an infected person. Person-to-person transmission of both CCHF and Lassa fever has occurred in health care settings after exposure to blood and secretions of infected patients. The incubation period for CCHF following a tick bite is usually 1-3 days (max 9 days) and following contact with blood or tissues is usually 5-6 days (max 13 days). The incubation period for Lassa fever ranges from 6-21 days. The onset of symptoms among CCHF patients is sudden with fever, myalgia and other signs and symptoms. The reported case fatality ratio for CCHF is between 3% and 30%. About 80% of human Lassa fever infections are mild or asymptomatic; the remaining cases have severe multi-system disease. The onset of disease in symptomatic patients is usually gradual starting with fever, general weakness and malaise. Lassa fever is difficult to distinguish from many other diseases which cause fever, including malaria, shigellosis, typhoid fever, yellow fever and other VHFs. The overall case fatality ratio is 1-15% among hospitalized patients."}, {"prompt": "How are Lassa and Crimean-Congo Haemorrhagic Fevers transmitted? related to Yellow Fever Disease", "completion": "CCHF spreads to humans either by tick-bites, or through contact with viraemic animal tissue immediately post-slaughter."}, {"prompt": "Explain the modes of transmission for Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "CCHF spreads to humans either by tick-bites, or through contact with viraemic animal tissue immediately post-slaughter."}, {"prompt": "What are the means of transmission for Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "CCHF spreads to humans either by tick-bites, or through contact with viraemic animal tissue immediately post-slaughter."}, {"prompt": "Describe how Lassa and Crimean-Congo Haemorrhagic Fevers are transmitted. related to Yellow Fever Disease", "completion": "CCHF spreads to humans either by tick-bites, or through contact with viraemic animal tissue immediately post-slaughter."}, {"prompt": "How are Lassa and Crimean-Congo Haemorrhagic Fevers transmitted to humans? related to Yellow Fever Disease", "completion": "CCHF spreads to humans either by tick-bites, or through contact with viraemic animal tissue immediately post-slaughter."}, {"prompt": "Why are Lassa and Crimean-Congo Haemorrhagic Fevers considered a priority? related to Yellow Fever Disease", "completion": "CCHF is endemic in Africa and outbreaks have been reported from Uganda, Mauritania, and South Africa. Mauritania reports a few cases each year and South Africa reported 165 laboratory-confirmed cases between 1981 and March 2006. Lassa fever is known to be endemic in Guinea, Liberia, Nigeria and Sierra Leone, but probably exists in other West African countries as well. Some studies indicate that 300,000 to 500,000 Lassa fever cases with 5,000 deaths occur each year in West Africa."}, {"prompt": "What makes Lassa and Crimean-Congo Haemorrhagic Fevers a priority for health authorities? related to Yellow Fever Disease", "completion": "CCHF is endemic in Africa and outbreaks have been reported from Uganda, Mauritania, and South Africa. Mauritania reports a few cases each year and South Africa reported 165 laboratory-confirmed cases between 1981 and March 2006. Lassa fever is known to be endemic in Guinea, Liberia, Nigeria and Sierra Leone, but probably exists in other West African countries as well. Some studies indicate that 300,000 to 500,000 Lassa fever cases with 5,000 deaths occur each year in West Africa."}, {"prompt": "How are Lassa and Crimean-Congo Haemorrhagic Fevers a priority in public health? related to Yellow Fever Disease", "completion": "CCHF is endemic in Africa and outbreaks have been reported from Uganda, Mauritania, and South Africa. Mauritania reports a few cases each year and South Africa reported 165 laboratory-confirmed cases between 1981 and March 2006. Lassa fever is known to be endemic in Guinea, Liberia, Nigeria and Sierra Leone, but probably exists in other West African countries as well. Some studies indicate that 300,000 to 500,000 Lassa fever cases with 5,000 deaths occur each year in West Africa."}, {"prompt": "Why are Lassa and Crimean-Congo Haemorrhagic Fevers considered significant health priorities? related to Yellow Fever Disease", "completion": "CCHF is endemic in Africa and outbreaks have been reported from Uganda, Mauritania, and South Africa. Mauritania reports a few cases each year and South Africa reported 165 laboratory-confirmed cases between 1981 and March 2006. Lassa fever is known to be endemic in Guinea, Liberia, Nigeria and Sierra Leone, but probably exists in other West African countries as well. Some studies indicate that 300,000 to 500,000 Lassa fever cases with 5,000 deaths occur each year in West Africa."}, {"prompt": "What are the surveillance goals for Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Early detection of cases and outbreaks, rapid investigation, and early laboratory verification of the aetiology of all suspected cases. Investigation of all suspected cases with contact tracing. Assess and monitor the spread and progress of epidemics and the effectiveness of control measures."}, {"prompt": "What are the objectives of surveillance for Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Early detection of cases and outbreaks, rapid investigation, and early laboratory verification of the aetiology of all suspected cases. Investigation of all suspected cases with contact tracing. Assess and monitor the spread and progress of epidemics and the effectiveness of control measures."}, {"prompt": "How is surveillance conducted for Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Early detection of cases and outbreaks, rapid investigation, and early laboratory verification of the aetiology of all suspected cases. Investigation of all suspected cases with contact tracing. Assess and monitor the spread and progress of epidemics and the effectiveness of control measures."}, {"prompt": "What is the purpose of surveillance for Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Early detection of cases and outbreaks, rapid investigation, and early laboratory verification of the aetiology of all suspected cases. Investigation of all suspected cases with contact tracing. Assess and monitor the spread and progress of epidemics and the effectiveness of control measures."}, {"prompt": "Why is surveillance important for Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Early detection of cases and outbreaks, rapid investigation, and early laboratory verification of the aetiology of all suspected cases. Investigation of all suspected cases with contact tracing. Assess and monitor the spread and progress of epidemics and the effectiveness of control measures."}, {"prompt": "What is the standard case definition for a suspected case of Crimean-Congo Haemorrhagic Fever? related to Yellow Fever Disease", "completion": "Illness with sudden onset of fever, malaise, weakness, irritability, headache, severe pain in limbs and loins and marked anorexia. Early development of flush on face and chest and conjunctival infection, haemorrhagic enanthem of soft palate, uvula and pharynx, and often fine petechial rash spreading from the chest and abdomen to the rest of the body, sometimes with large purpuric areas."}, {"prompt": "Describe the standard case definition for a suspected case of Crimean-Congo Haemorrhagic Fever. related to Yellow Fever Disease", "completion": "Illness with sudden onset of fever, malaise, weakness, irritability, headache, severe pain in limbs and loins and marked anorexia. Early development of flush on face and chest and conjunctival infection, haemorrhagic enanthem of soft palate, uvula and pharynx, and often fine petechial rash spreading from the chest and abdomen to the rest of the body, sometimes with large purpuric areas."}, {"prompt": "What are the criteria for defining a suspected case of Crimean-Congo Haemorrhagic Fever? related to Yellow Fever Disease", "completion": "Illness with sudden onset of fever, malaise, weakness, irritability, headache, severe pain in limbs and loins and marked anorexia. Early development of flush on face and chest and conjunctival infection, haemorrhagic enanthem of soft palate, uvula and pharynx, and often fine petechial rash spreading from the chest and abdomen to the rest of the body, sometimes with large purpuric areas."}, {"prompt": "Explain the criteria for defining a suspected case of Crimean-Congo Haemorrhagic Fever. related to Yellow Fever Disease", "completion": "Illness with sudden onset of fever, malaise, weakness, irritability, headache, severe pain in limbs and loins and marked anorexia. Early development of flush on face and chest and conjunctival infection, haemorrhagic enanthem of soft palate, uvula and pharynx, and often fine petechial rash spreading from the chest and abdomen to the rest of the body, sometimes with large purpuric areas."}, {"prompt": "What is the standard case definition for a confirmed case of Crimean-Congo Haemorrhagic Fever? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation (positive IgM antibody, PCR, viral isolation or IgG seroconversion by ELISA or IFA) or epidemiologic link to confirmed cases or outbreak."}, {"prompt": "Elaborate on the standard case definition for a confirmed case of Crimean-Congo Haemorrhagic Fever. related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation (positive IgM antibody, PCR, viral isolation or IgG seroconversion by ELISA or IFA) or epidemiologic link to confirmed cases or outbreak."}, {"prompt": "What are the criteria for defining a confirmed case of Crimean-Congo Haemorrhagic Fever? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation (positive IgM antibody, PCR, viral isolation or IgG seroconversion by ELISA or IFA) or epidemiologic link to confirmed cases or outbreak."}, {"prompt": "Explain the criteria for defining a confirmed case of Crimean-Congo Haemorrhagic Fever. related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation (positive IgM antibody, PCR, viral isolation or IgG seroconversion by ELISA or IFA) or epidemiologic link to confirmed cases or outbreak."}, {"prompt": "What is the standard case definition for a suspected case of Lassa Fever? related to Yellow Fever Disease", "completion": "Illness with gradual onset with one or more of the following: malaise, fever, headache, sore throat, cough, nausea, vomiting, diarrhoea, myalgia, chest pain hearing loss and a history of contact with excreta of rodents or with a case of Lassa Fever."}, {"prompt": "Describe the standard case definition for a suspected case of Lassa Fever. related to Yellow Fever Disease", "completion": "Illness with gradual onset with one or more of the following: malaise, fever, headache, sore throat, cough, nausea, vomiting, diarrhoea, myalgia, chest pain hearing loss and a history of contact with excreta of rodents or with a case of Lassa Fever."}, {"prompt": "What are the criteria for defining a suspected case of Lassa Fever? related to Yellow Fever Disease", "completion": "Illness with gradual onset with one or more of the following: malaise, fever, headache, sore throat, cough, nausea, vomiting, diarrhoea, myalgia, chest pain hearing loss and a history of contact with excreta of rodents or with a case of Lassa Fever."}, {"prompt": "Explain the criteria for defining a suspected case of Lassa Fever. related to Yellow Fever Disease", "completion": "Illness with gradual onset with one or more of the following: malaise, fever, headache, sore throat, cough, nausea, vomiting, diarrhoea, myalgia, chest pain hearing loss and a history of contact with excreta of rodents or with a case of Lassa Fever."}, {"prompt": "What is the standard case definition for a confirmed case of Lassa Fever? related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed (positive IgM antibody, PCR or virus isolation) or epidemiologically linked to a laboratory confirmed case."}, {"prompt": "Elaborate on the standard case definition for a confirmed case of Lassa Fever. related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed (positive IgM antibody, PCR or virus isolation) or epidemiologically linked to a laboratory confirmed case."}, {"prompt": "What are the criteria for defining a confirmed case of Lassa Fever? related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed (positive IgM antibody, PCR or virus isolation) or epidemiologically linked to a laboratory confirmed case."}, {"prompt": "Explain the criteria for defining a confirmed case of Lassa Fever. related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed (positive IgM antibody, PCR or virus isolation) or epidemiologically linked to a laboratory confirmed case."}, {"prompt": "How should you respond when the alert threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached? related to Yellow Fever Disease", "completion": "Report case-based information immediately to the appropriate levels. Suspected cases should be isolated from other patients and strict barrier nursing techniques implemented. Standard infection control precautions should be enhanced throughout the healthcare setting. Treat and manage the patient with supportive care. Collect specimen to confirm the case(s). Case-contact follow-up and active case search for additional cases."}, {"prompt": "Explain the response procedures when the alert threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached. related to Yellow Fever Disease", "completion": "Report case-based information immediately to the appropriate levels. Suspected cases should be isolated from other patients and strict barrier nursing techniques implemented. Standard infection control precautions should be enhanced throughout the healthcare setting. Treat and manage the patient with supportive care. Collect specimen to confirm the case(s). Case-contact follow-up and active case search for additional cases."}, {"prompt": "What actions should be taken when the alert threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached? related to Yellow Fever Disease", "completion": "Report case-based information immediately to the appropriate levels. Suspected cases should be isolated from other patients and strict barrier nursing techniques implemented. Standard infection control precautions should be enhanced throughout the healthcare setting. Treat and manage the patient with supportive care. Collect specimen to confirm the case(s). Case-contact follow-up and active case search for additional cases."}, {"prompt": "Describe the steps to take when the alert threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached. related to Yellow Fever Disease", "completion": "Report case-based information immediately to the appropriate levels. Suspected cases should be isolated from other patients and strict barrier nursing techniques implemented. Standard infection control precautions should be enhanced throughout the healthcare setting. Treat and manage the patient with supportive care. Collect specimen to confirm the case(s). Case-contact follow-up and active case search for additional cases."}, {"prompt": "What measures should be implemented when the alert threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached? related to Yellow Fever Disease", "completion": "Report case-based information immediately to the appropriate levels. Suspected cases should be isolated from other patients and strict barrier nursing techniques implemented. Standard infection control precautions should be enhanced throughout the healthcare setting. Treat and manage the patient with supportive care. Collect specimen to confirm the case(s). Case-contact follow-up and active case search for additional cases."}, {"prompt": "How should you respond when the action threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached? related to Yellow Fever Disease", "completion": "Maintain strict VHF infection control practices throughout the outbreak. Mobilize the community for early detection and care and conduct community education about how the disease is transmitted and how to implement infection control in the home care setting. For CCHF, educate the public about the mode of tick transmission and enhance rodent control activities for Lassa fever. Conduct active searches for additional cases. Request additional help from other levels as needed. Establish an isolation ward to handle additional cases that may come to the health centre."}, {"prompt": "Describe the response procedures when the action threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached. related to Yellow Fever Disease", "completion": "Maintain strict VHF infection control practices throughout the outbreak. Mobilize the community for early detection and care and conduct community education about how the disease is transmitted and how to implement infection control in the home care setting. For CCHF, educate the public about the mode of tick transmission and enhance rodent control activities for Lassa fever. Conduct active searches for additional cases. Request additional help from other levels as needed. Establish an isolation ward to handle additional cases that may come to the health centre."}, {"prompt": "What actions should be taken when the action threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached? related to Yellow Fever Disease", "completion": "Maintain strict VHF infection control practices throughout the outbreak. Mobilize the community for early detection and care and conduct community education about how the disease is transmitted and how to implement infection control in the home care setting. For CCHF, educate the public about the mode of tick transmission and enhance rodent control activities for Lassa fever. Conduct active searches for additional cases. Request additional help from other levels as needed. Establish an isolation ward to handle additional cases that may come to the health centre."}, {"prompt": "Describe the measures to implement when the action threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached. related to Yellow Fever Disease", "completion": "Maintain strict VHF infection control practices throughout the outbreak. Mobilize the community for early detection and care and conduct community education about how the disease is transmitted and how to implement infection control in the home care setting. For CCHF, educate the public about the mode of tick transmission and enhance rodent control activities for Lassa fever. Conduct active searches for additional cases. Request additional help from other levels as needed. Establish an isolation ward to handle additional cases that may come to the health centre."}, {"prompt": "What should be done when the action threshold for Lassa and Crimean-Congo Haemorrhagic Fevers is reached? related to Yellow Fever Disease", "completion": "Maintain strict VHF infection control practices throughout the outbreak. Mobilize the community for early detection and care and conduct community education about how the disease is transmitted and how to implement infection control in the home care setting. For CCHF, educate the public about the mode of tick transmission and enhance rodent control activities for Lassa fever. Conduct active searches for additional cases. Request additional help from other levels as needed. Establish an isolation ward to handle additional cases that may come to the health centre."}, {"prompt": "How should data about a person with Lassa and Crimean-Congo Haemorrhagic Fevers be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Implement immediate case-based reporting of cases and deaths. Analyze age and sex distribution. Assess risk factors and plan disease control interventions accordingly."}, {"prompt": "What are the steps to analyze and interpret data about a person with Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Implement immediate case-based reporting of cases and deaths. Analyze age and sex distribution. Assess risk factors and plan disease control interventions accordingly."}, {"prompt": "Describe how to analyze and interpret data about a person with Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Implement immediate case-based reporting of cases and deaths. Analyze age and sex distribution. Assess risk factors and plan disease control interventions accordingly."}, {"prompt": "What steps should be taken to analyze and interpret data about a person with Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Implement immediate case-based reporting of cases and deaths. Analyze age and sex distribution. Assess risk factors and plan disease control interventions accordingly."}, {"prompt": "How should data about time in the context of Lassa and Crimean-Congo Haemorrhagic Fevers be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly. Construct an epidemic curve during the outbreak."}, {"prompt": "Explain the process of analyzing and interpreting data about time in the context of Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly. Construct an epidemic curve during the outbreak."}, {"prompt": "What are the steps to analyze and interpret data about time in the context of Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly. Construct an epidemic curve during the outbreak."}, {"prompt": "Describe how to analyze and interpret data about time in the context of Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Graph cases and deaths daily/weekly. Construct an epidemic curve during the outbreak."}, {"prompt": "How should data about place in the context of Lassa and Crimean-Congo Haemorrhagic Fevers be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Map locations of cases' households."}, {"prompt": "Explain the process of analyzing and interpreting data about place in the context of Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Map locations of cases' households."}, {"prompt": "What are the steps to analyze and interpret data about place in the context of Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Map locations of cases' households."}, {"prompt": "Describe how to analyze and interpret data about place in the context of Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Map locations of cases' households."}, {"prompt": "How are Lassa and Crimean-Congo Haemorrhagic Fevers diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Presence of IgM antibodies against CCHF, or Lassa Fever. Specimens that can be used for testing include: For ELISA - Whole blood, serum or plasma; For PCR - Whole blood or blood clot, serum/plasma or tissue; For Immunohistochemistry - Skin or tissue specimens from fatal cases. Specimens should be handled and transported with extreme caution and protective clothing. For ELISA or PCR, refrigerate serum or clot, and freeze tissue specimens. For Immunohistochemistry, fix skin snip specimen in formalin and store at room temperature."}, {"prompt": "Explain the laboratory diagnosis of Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "Presence of IgM antibodies against CCHF, or Lassa Fever. Specimens that can be used for testing include: For ELISA - Whole blood, serum or plasma; For PCR - Whole blood or blood clot, serum/plasma or tissue; For Immunohistochemistry - Skin or tissue specimens from fatal cases. Specimens should be handled and transported with extreme caution and protective clothing. For ELISA or PCR, refrigerate serum or clot, and freeze tissue specimens. For Immunohistochemistry, fix skin snip specimen in formalin and store at room temperature."}, {"prompt": "What are the steps for the laboratory diagnosis of Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "Presence of IgM antibodies against CCHF, or Lassa Fever. Specimens that can be used for testing include: For ELISA - Whole blood, serum or plasma; For PCR - Whole blood or blood clot, serum/plasma or tissue; For Immunohistochemistry - Skin or tissue specimens from fatal cases. Specimens should be handled and transported with extreme caution and protective clothing. For ELISA or PCR, refrigerate serum or clot, and freeze tissue specimens. For Immunohistochemistry, fix skin snip specimen in formalin and store at room temperature."}, {"prompt": "Describe how Lassa and Crimean-Congo Haemorrhagic Fevers are diagnosed in the laboratory. related to Yellow Fever Disease", "completion": "Presence of IgM antibodies against CCHF, or Lassa Fever. Specimens that can be used for testing include: For ELISA - Whole blood, serum or plasma; For PCR - Whole blood or blood clot, serum/plasma or tissue; For Immunohistochemistry - Skin or tissue specimens from fatal cases. Specimens should be handled and transported with extreme caution and protective clothing. For ELISA or PCR, refrigerate serum or clot, and freeze tissue specimens. For Immunohistochemistry, fix skin snip specimen in formalin and store at room temperature."}, {"prompt": "What are the references for Lassa and Crimean-Congo Haemorrhagic Fevers? related to Yellow Fever Disease", "completion": "1. Interim Infection Control Recommendations for Care of Patients with Suspected or Confirmed Filovirus (Ebola, Marburg) Hemorrhagic Fever. BDP/EPR/WHO, 2008.\n2. Infection control for VHF in the African health care setting, WHO, 1998. WHO/EMC\n3. Ergonul O. Crimean-Congo haemorrhagic fever. Lancet Infect Dis 2006;6: 203-14.\n4. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n5. WHO Fact Sheet No 208, Crimean-Congo Haemorrhagic Fever, revised November 2001\n6. WHO Fact Sheet No 179, Lassa Fever, revised April 2005."}, {"prompt": "Provide the references for Lassa and Crimean-Congo Haemorrhagic Fevers. related to Yellow Fever Disease", "completion": "1. Interim Infection Control Recommendations for Care of Patients with Suspected or Confirmed Filovirus (Ebola, Marburg) Hemorrhagic Fever. BDP/EPR/WHO, 2008.\n2. Infection control for VHF in the African health care setting, WHO, 1998. WHO/EMC\n3. Ergonul O. Crimean-Congo haemorrhagic fever. Lancet Infect Dis 2006;6: 203-14.\n4. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n5. WHO Fact Sheet No 208, Crimean-Congo Haemorrhagic Fever, revised November 2001\n6. WHO Fact Sheet No 179, Lassa Fever, revised April 2005."}, {"prompt": "Explain Road traffic accidents. related to Yellow Fever Disease", "completion": "Injury is a physical damage resulting when the human body is briefly or suddenly subjected to levels of energy exceeding its physiological tolerance or the impairment in function resulting from the lack of one or more vital elements (water, air, warmth). The energy causing the injury can be mechanical, electrical, thermal, radiant, or chemical. Injury is classified as intentional and unintentional. All injuries account for 10% of the world's deaths. 5.8 million People die each year as a result of different types of injuries. Of all the systems that people deal with on a daily basis; road transport is the most complex and the most dangerous. Road traffic accidents result in unintentional injury. A traffic collision (motor vehicle collision, motor vehicle accident, car accident, or car crash) occurs when a road vehicle collides with another vehicle, pedestrian, animal, road debris, or other geographical or architectural obstacle. Traffic collisions can result in injury, property damage, and death."}, {"prompt": "Describe Road traffic accidents. related to Yellow Fever Disease", "completion": "Injury is a physical damage resulting when the human body is briefly or suddenly subjected to levels of energy exceeding its physiological tolerance or the impairment in function resulting from the lack of one or more vital elements (water, air, warmth). The energy causing the injury can be mechanical, electrical, thermal, radiant, or chemical. Injury is classified as intentional and unintentional. All injuries account for 10% of the world's deaths. 5.8 million People die each year as a result of different types of injuries. Of all the systems that people deal with on a daily basis; road transport is the most complex and the most dangerous. Road traffic accidents result in unintentional injury. A traffic collision (motor vehicle collision, motor vehicle accident, car accident, or car crash) occurs when a road vehicle collides with another vehicle, pedestrian, animal, road debris, or other geographical or architectural obstacle. Traffic collisions can result in injury, property damage, and death."}, {"prompt": "Elaborate on Road traffic accidents. related to Yellow Fever Disease", "completion": "Injury is a physical damage resulting when the human body is briefly or suddenly subjected to levels of energy exceeding its physiological tolerance or the impairment in function resulting from the lack of one or more vital elements (water, air, warmth). The energy causing the injury can be mechanical, electrical, thermal, radiant, or chemical. Injury is classified as intentional and unintentional. All injuries account for 10% of the world's deaths. 5.8 million People die each year as a result of different types of injuries. Of all the systems that people deal with on a daily basis; road transport is the most complex and the most dangerous. Road traffic accidents result in unintentional injury. A traffic collision (motor vehicle collision, motor vehicle accident, car accident, or car crash) occurs when a road vehicle collides with another vehicle, pedestrian, animal, road debris, or other geographical or architectural obstacle. Traffic collisions can result in injury, property damage, and death."}, {"prompt": "Define Road traffic accidents. related to Yellow Fever Disease", "completion": "Injury is a physical damage resulting when the human body is briefly or suddenly subjected to levels of energy exceeding its physiological tolerance or the impairment in function resulting from the lack of one or more vital elements (water, air, warmth). The energy causing the injury can be mechanical, electrical, thermal, radiant, or chemical. Injury is classified as intentional and unintentional. All injuries account for 10% of the world's deaths. 5.8 million People die each year as a result of different types of injuries. Of all the systems that people deal with on a daily basis; road transport is the most complex and the most dangerous. Road traffic accidents result in unintentional injury. A traffic collision (motor vehicle collision, motor vehicle accident, car accident, or car crash) occurs when a road vehicle collides with another vehicle, pedestrian, animal, road debris, or other geographical or architectural obstacle. Traffic collisions can result in injury, property damage, and death."}, {"prompt": "What is the nature of Road traffic accidents? related to Yellow Fever Disease", "completion": "Injury is a physical damage resulting when the human body is briefly or suddenly subjected to levels of energy exceeding its physiological tolerance or the impairment in function resulting from the lack of one or more vital elements (water, air, warmth). The energy causing the injury can be mechanical, electrical, thermal, radiant, or chemical. Injury is classified as intentional and unintentional. All injuries account for 10% of the world's deaths. 5.8 million People die each year as a result of different types of injuries. Of all the systems that people deal with on a daily basis; road transport is the most complex and the most dangerous. Road traffic accidents result in unintentional injury. A traffic collision (motor vehicle collision, motor vehicle accident, car accident, or car crash) occurs when a road vehicle collides with another vehicle, pedestrian, animal, road debris, or other geographical or architectural obstacle. Traffic collisions can result in injury, property damage, and death."}, {"prompt": "Why are Road traffic accidents a global health priority? related to Yellow Fever Disease", "completion": "Worldwide, the number of people killed in road traffic crashes each year is estimated at 1.2 million, while the number of injured could be as high as 50 million. Road traffic injuries are a major but neglected global public health problem, requiring concerted efforts for effective and sustainable prevention. Road traffic injuries continue to be among the leading causes of death and disability among young people aged between 5 and 44 years and the leading cause of death in the category of people between 15-29 years. The majority of such deaths are currently among 'vulnerable road users'-pedestrians, pedal cyclists, and motorcyclists."}, {"prompt": "What makes Road traffic accidents a priority in global health efforts? related to Yellow Fever Disease", "completion": "Worldwide, the number of people killed in road traffic crashes each year is estimated at 1.2 million, while the number of injured could be as high as 50 million. Road traffic injuries are a major but neglected global public health problem, requiring concerted efforts for effective and sustainable prevention. Road traffic injuries continue to be among the leading causes of death and disability among young people aged between 5 and 44 years and the leading cause of death in the category of people between 15-29 years. The majority of such deaths are currently among 'vulnerable road users'-pedestrians, pedal cyclists, and motorcyclists."}, {"prompt": "What are the reasons behind Road traffic accidents being a global health priority? related to Yellow Fever Disease", "completion": "Worldwide, the number of people killed in road traffic crashes each year is estimated at 1.2 million, while the number of injured could be as high as 50 million. Road traffic injuries are a major but neglected global public health problem, requiring concerted efforts for effective and sustainable prevention. Road traffic injuries continue to be among the leading causes of death and disability among young people aged between 5 and 44 years and the leading cause of death in the category of people between 15-29 years. The majority of such deaths are currently among 'vulnerable road users'-pedestrians, pedal cyclists, and motorcyclists."}, {"prompt": "What factors contribute to Road traffic accidents being a global health priority? related to Yellow Fever Disease", "completion": "Worldwide, the number of people killed in road traffic crashes each year is estimated at 1.2 million, while the number of injured could be as high as 50 million. Road traffic injuries are a major but neglected global public health problem, requiring concerted efforts for effective and sustainable prevention. Road traffic injuries continue to be among the leading causes of death and disability among young people aged between 5 and 44 years and the leading cause of death in the category of people between 15-29 years. The majority of such deaths are currently among 'vulnerable road users'-pedestrians, pedal cyclists, and motorcyclists."}, {"prompt": "What are the goals of surveillance for Road traffic accidents? related to Yellow Fever Disease", "completion": "Estimate and monitor incidence of road traffic injuries and related outcomes. Identify risk factors and high-risk areas to inform prevention policy and programs. Evaluate programs aimed at preventing road traffic injuries. Establish alert thresholds for fatalities to allow health facility personnel to review care and services provided to injured persons. Establish incidence alert thresholds and monitor trends to enable district health personnel inform relevant stakeholders."}, {"prompt": "What is the purpose of surveillance for Road traffic accidents? related to Yellow Fever Disease", "completion": "Estimate and monitor incidence of road traffic injuries and related outcomes. Identify risk factors and high-risk areas to inform prevention policy and programs. Evaluate programs aimed at preventing road traffic injuries. Establish alert thresholds for fatalities to allow health facility personnel to review care and services provided to injured persons. Establish incidence alert thresholds and monitor trends to enable district health personnel inform relevant stakeholders."}, {"prompt": "What are the surveillance objectives for Road traffic accidents? related to Yellow Fever Disease", "completion": "Estimate and monitor incidence of road traffic injuries and related outcomes. Identify risk factors and high-risk areas to inform prevention policy and programs. Evaluate programs aimed at preventing road traffic injuries. Establish alert thresholds for fatalities to allow health facility personnel to review care and services provided to injured persons. Establish incidence alert thresholds and monitor trends to enable district health personnel inform relevant stakeholders."}, {"prompt": "How is a road traffic injury defined? related to Yellow Fever Disease", "completion": "Any person who has sustained an injury as a result of a road traffic crash presenting for the first time."}, {"prompt": "What is the definition of a road traffic injury? related to Yellow Fever Disease", "completion": "Any person who has sustained an injury as a result of a road traffic crash presenting for the first time."}, {"prompt": "Define a road traffic injury. related to Yellow Fever Disease", "completion": "Any person who has sustained an injury as a result of a road traffic crash presenting for the first time."}, {"prompt": "What criteria are used to define a road traffic injury? related to Yellow Fever Disease", "completion": "Any person who has sustained an injury as a result of a road traffic crash presenting for the first time."}, {"prompt": "What is considered a road traffic fatality? related to Yellow Fever Disease", "completion": "Any person killed immediately or dying within 30 days as a result of an injury crash."}, {"prompt": "How are road traffic fatalities defined? related to Yellow Fever Disease", "completion": "Any person killed immediately or dying within 30 days as a result of an injury crash."}, {"prompt": "What is the standard case definition for a road traffic fatality? related to Yellow Fever Disease", "completion": "Any person killed immediately or dying within 30 days as a result of an injury crash."}, {"prompt": "When the alert threshold for Road traffic accidents is reached, how should you respond? related to Yellow Fever Disease", "completion": "Promote primary prevention by supporting interventions to address risk factors. Review and monitor care and services provided to injured persons. Review arrangements for mass casualty management."}, {"prompt": "What should you do when the alert threshold for Road traffic accidents is reached? related to Yellow Fever Disease", "completion": "Promote primary prevention by supporting interventions to address risk factors. Review and monitor care and services provided to injured persons. Review arrangements for mass casualty management."}, {"prompt": "When the alert threshold for Road traffic accidents is triggered, what actions are required? related to Yellow Fever Disease", "completion": "Promote primary prevention by supporting interventions to address risk factors. Review and monitor care and services provided to injured persons. Review arrangements for mass casualty management."}, {"prompt": "When the action threshold for Road traffic accidents is reached, what should you do? related to Yellow Fever Disease", "completion": "Step up enforcement of measures to address risk factors. Activate mass casualty management system."}, {"prompt": "What actions are needed when the action threshold for Road traffic accidents is reached? related to Yellow Fever Disease", "completion": "Step up enforcement of measures to address risk factors. Activate mass casualty management system."}, {"prompt": "What steps should be taken in response to reaching the action threshold for Road traffic accidents? related to Yellow Fever Disease", "completion": "Step up enforcement of measures to address risk factors. Activate mass casualty management system."}, {"prompt": "How should data about a person involved in a road traffic accident be analyzed? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by sex, age, and other demographic factors."}, {"prompt": "What are the methods of analyzing data about individuals involved in road traffic accidents? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by sex, age, and other demographic factors."}, {"prompt": "What demographic factors should be analyzed when studying road traffic accidents? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by sex, age, and other demographic factors."}, {"prompt": "How should data about time in the context of road traffic accidents be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Graphs to show monthly figures of cases and deaths, curves for the year to depict trend."}, {"prompt": "What graphical representations can be used to analyze time-related data in road traffic accidents? related to Yellow Fever Disease", "completion": "Graphs to show monthly figures of cases and deaths, curves for the year to depict trend."}, {"prompt": "How can trends in road traffic accidents be visualized using graphs? related to Yellow Fever Disease", "completion": "Graphs to show monthly figures of cases and deaths, curves for the year to depict trend."}, {"prompt": "How should data about place in the context of road traffic accidents be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Plot location of cases and identify high-risk areas."}, {"prompt": "What are the methods for analyzing geographical data related to road traffic accidents? related to Yellow Fever Disease", "completion": "Plot location of cases and identify high-risk areas."}, {"prompt": "How can spatial analysis contribute to understanding road traffic accidents? related to Yellow Fever Disease", "completion": "Plot location of cases and identify high-risk areas."}, {"prompt": "How are Road traffic accidents diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Diagnosis of road traffic injuries can be further informed through laboratory testing, which may include imaging of the injured person - when required."}, {"prompt": "What laboratory tests are used for diagnosing Road traffic accidents? related to Yellow Fever Disease", "completion": "Diagnosis of road traffic injuries can be further informed through laboratory testing, which may include imaging of the injured person - when required."}, {"prompt": "What role does laboratory testing play in diagnosing Road traffic accidents? related to Yellow Fever Disease", "completion": "Diagnosis of road traffic injuries can be further informed through laboratory testing, which may include imaging of the injured person - when required."}, {"prompt": "What are the references for Road traffic accidents? related to Yellow Fever Disease", "completion": "1. WHO-2004, World Health report.\n2. WHO- 2010 Status report on Road Safety in Africa.\n3. WHO, 2004-Peden,M.; et al (eds) World report on Road Traffic Injury prevention.\n4. WHO, 2001- Holder Y. Peden M., Krug E. et al(eds) Injury Surveillance GuidelinesvGeneva.\n5. Harvey A,(Ed).Data systems, Geneva, World Health Organisation, 2010."}, {"prompt": "Where can I find references for Road traffic accidents? related to Yellow Fever Disease", "completion": "1. WHO-2004, World Health report.\n2. WHO- 2010 Status report on Road Safety in Africa.\n3. WHO, 2004-Peden,M.; et al (eds) World report on Road Traffic Injury prevention.\n4. WHO, 2001- Holder Y. Peden M., Krug E. et al(eds) Injury Surveillance GuidelinesvGeneva.\n5. Harvey A,(Ed).Data systems, Geneva, World Health Organisation, 2010."}, {"prompt": "What sources can be referenced for information about Road traffic accidents? related to Yellow Fever Disease", "completion": "1. WHO-2004, World Health report.\n2. WHO- 2010 Status report on Road Safety in Africa.\n3. WHO, 2004-Peden,M.; et al (eds) World report on Road Traffic Injury prevention.\n4. WHO, 2001- Holder Y. Peden M., Krug E. et al(eds) Injury Surveillance GuidelinesvGeneva.\n5. Harvey A,(Ed).Data systems, Geneva, World Health Organisation, 2010."}, {"prompt": "Where can I find authoritative information about Road traffic accidents? related to Yellow Fever Disease", "completion": "1. WHO-2004, World Health report.\n2. WHO- 2010 Status report on Road Safety in Africa.\n3. WHO, 2004-Peden,M.; et al (eds) World report on Road Traffic Injury prevention.\n4. WHO, 2001- Holder Y. Peden M., Krug E. et al(eds) Injury Surveillance GuidelinesvGeneva.\n5. Harvey A,(Ed).Data systems, Geneva, World Health Organisation, 2010."}, {"prompt": "Explain Influenza-like Illness (ILI). related to Yellow Fever Disease", "completion": "Influenza-like Illness (ILI) refers to respiratory infections that are a significant cause of infectious disease morbidity and mortality worldwide. Mortality rates are especially high among infants, children, and the elderly. Common pathogens causing these infections include Streptococcus pneumoniae, Haemophilus influenzae type b, Staphylococcus aureus, Respiratory Syncytial Virus (RSV), measles virus, human parainfluenza viruses, influenza virus, and varicella virus. Surveillance for these infections is based on the ILI case definition. This type of surveillance or investigation helps in identifying the specific disease-causing pathogen. It's crucial to understand the epidemiology and seasonality of respiratory infections in Africa to optimize public health strategies for their prevention and control."}, {"prompt": "Describe Influenza-like Illness (ILI). related to Yellow Fever Disease", "completion": "Influenza-like Illness (ILI) refers to respiratory infections that are a significant cause of infectious disease morbidity and mortality worldwide. Mortality rates are especially high among infants, children, and the elderly. Common pathogens causing these infections include Streptococcus pneumoniae, Haemophilus influenzae type b, Staphylococcus aureus, Respiratory Syncytial Virus (RSV), measles virus, human parainfluenza viruses, influenza virus, and varicella virus. Surveillance for these infections is based on the ILI case definition. This type of surveillance or investigation helps in identifying the specific disease-causing pathogen. It's crucial to understand the epidemiology and seasonality of respiratory infections in Africa to optimize public health strategies for their prevention and control."}, {"prompt": "Elaborate on Influenza-like Illness (ILI). related to Yellow Fever Disease", "completion": "Influenza-like Illness (ILI) refers to respiratory infections that are a significant cause of infectious disease morbidity and mortality worldwide. Mortality rates are especially high among infants, children, and the elderly. Common pathogens causing these infections include Streptococcus pneumoniae, Haemophilus influenzae type b, Staphylococcus aureus, Respiratory Syncytial Virus (RSV), measles virus, human parainfluenza viruses, influenza virus, and varicella virus. Surveillance for these infections is based on the ILI case definition. This type of surveillance or investigation helps in identifying the specific disease-causing pathogen. It's crucial to understand the epidemiology and seasonality of respiratory infections in Africa to optimize public health strategies for their prevention and control."}, {"prompt": "Define Influenza-like Illness (ILI). related to Yellow Fever Disease", "completion": "Influenza-like Illness (ILI) refers to respiratory infections that are a significant cause of infectious disease morbidity and mortality worldwide. Mortality rates are especially high among infants, children, and the elderly. Common pathogens causing these infections include Streptococcus pneumoniae, Haemophilus influenzae type b, Staphylococcus aureus, Respiratory Syncytial Virus (RSV), measles virus, human parainfluenza viruses, influenza virus, and varicella virus. Surveillance for these infections is based on the ILI case definition. This type of surveillance or investigation helps in identifying the specific disease-causing pathogen. It's crucial to understand the epidemiology and seasonality of respiratory infections in Africa to optimize public health strategies for their prevention and control."}, {"prompt": "What is the nature of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Influenza-like Illness (ILI) refers to respiratory infections that are a significant cause of infectious disease morbidity and mortality worldwide. Mortality rates are especially high among infants, children, and the elderly. Common pathogens causing these infections include Streptococcus pneumoniae, Haemophilus influenzae type b, Staphylococcus aureus, Respiratory Syncytial Virus (RSV), measles virus, human parainfluenza viruses, influenza virus, and varicella virus. Surveillance for these infections is based on the ILI case definition. This type of surveillance or investigation helps in identifying the specific disease-causing pathogen. It's crucial to understand the epidemiology and seasonality of respiratory infections in Africa to optimize public health strategies for their prevention and control."}, {"prompt": "Why is Influenza-like Illness (ILI) a global health priority? related to Yellow Fever Disease", "completion": "The threat of respiratory infections from novel organisms that have the potential for epidemics or pandemics makes special precautions and preparedness essential. Events that may be of international public health concern include Severe Acute Respiratory Syndrome (SARS), human influenza caused by a new subtype (including episodes of avian influenza), pneumonic plague, and novel agents that can lead to large-scale SARI outbreaks with high morbidity and mortality."}, {"prompt": "What makes Influenza-like Illness (ILI) a priority in global health efforts? related to Yellow Fever Disease", "completion": "The threat of respiratory infections from novel organisms that have the potential for epidemics or pandemics makes special precautions and preparedness essential. Events that may be of international public health concern include Severe Acute Respiratory Syndrome (SARS), human influenza caused by a new subtype (including episodes of avian influenza), pneumonic plague, and novel agents that can lead to large-scale SARI outbreaks with high morbidity and mortality."}, {"prompt": "What are the reasons behind Influenza-like Illness (ILI) being a global health priority? related to Yellow Fever Disease", "completion": "The threat of respiratory infections from novel organisms that have the potential for epidemics or pandemics makes special precautions and preparedness essential. Events that may be of international public health concern include Severe Acute Respiratory Syndrome (SARS), human influenza caused by a new subtype (including episodes of avian influenza), pneumonic plague, and novel agents that can lead to large-scale SARI outbreaks with high morbidity and mortality."}, {"prompt": "Who is most vulnerable to Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Those who are most vulnerable to Influenza-like Illness (ILI) include infants, children, and the elderly, with mortality rates being especially high in these groups. Other vulnerable groups include individuals with immunocompromising conditions and health workers exposed to ILI patients."}, {"prompt": "What population groups are at the highest risk of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Those who are at the highest risk of Influenza-like Illness (ILI) include infants, children, and the elderly, with mortality rates being especially high in these groups. Other vulnerable groups include individuals with immunocompromising conditions and health workers exposed to ILI patients."}, {"prompt": "Who is most susceptible to Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Those who are most vulnerable to Influenza-like Illness (ILI) include infants, children, and the elderly, with mortality rates being especially high in these groups. Other vulnerable groups include individuals with immunocompromising conditions and health workers exposed to ILI patients."}, {"prompt": "What are the main goals of surveillance for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "1) Early detection of unusual events indicating a shift in disease severity or pattern related to influenza or the emergence of a new influenza strain.\n2) Establish and monitor baseline rates of severe respiratory disease, including monitoring the severity and impact of influenza.\n3) Describe and monitor vulnerable groups at the highest risk of severe disease.\n4) Detect changes in circulating viruses, including antigenic or genetic changes or the appearance of antiviral resistance."}, {"prompt": "What is the purpose of surveillance for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "1) Early detection of unusual events indicating a shift in disease severity or pattern related to influenza or the emergence of a new influenza strain.\n2) Establish and monitor baseline rates of severe respiratory disease, including monitoring the severity and impact of influenza.\n3) Describe and monitor vulnerable groups at the highest risk of severe disease.\n4) Detect changes in circulating viruses, including antigenic or genetic changes or the appearance of antiviral resistance."}, {"prompt": "What are the objectives of surveillance for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "1) Early detection of unusual events indicating a shift in disease severity or pattern related to influenza or the emergence of a new influenza strain.\n2) Establish and monitor baseline rates of severe respiratory disease, including monitoring the severity and impact of influenza.\n3) Describe and monitor vulnerable groups at the highest risk of severe disease.\n4) Detect changes in circulating viruses, including antigenic or genetic changes or the appearance of antiviral resistance."}, {"prompt": "How is a suspected new case of Influenza-like Illness (ILI) defined? related to Yellow Fever Disease", "completion": "A suspected new case of ILI is defined as a person, child or adult, presenting with sudden onset of fever greater than 38 \u00b0C combined with cough or sore throat in the absence of other diagnoses."}, {"prompt": "What are the criteria for identifying a suspected new case of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "A suspected new case of ILI is defined as a person, child or adult, presenting with sudden onset of fever greater than 38 \u00b0C combined with cough or sore throat in the absence of other diagnoses."}, {"prompt": "How is a confirmed case of Influenza-like Illness (ILI) defined? related to Yellow Fever Disease", "completion": "A confirmed case of ILI meets the clinical case definition and has been laboratory confirmed, with positive results for the influenza virus."}, {"prompt": "What are the criteria for confirming a case of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "A confirmed case of ILI meets the clinical case definition and has been laboratory confirmed, with positive results for the influenza virus."}, {"prompt": "What are the recommended public health actions to address Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "1) Health promotion focusing on respiratory infections, including community-based education on behavior change and the adoption of healthy lifestyles.\n2) Promote secondary prevention and treatment interventions at health facilities according to national guidelines."}, {"prompt": "How can public health actions help mitigate Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "1) Health promotion focusing on respiratory infections, including community-based education on behavior change and the adoption of healthy lifestyles.\n2) Promote secondary prevention and treatment interventions at health facilities according to national guidelines."}, {"prompt": "What actions are recommended by public health authorities for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "1) Health promotion focusing on respiratory infections, including community-based education on behavior change and the adoption of healthy lifestyles.\n2) Promote secondary prevention and treatment interventions at health facilities according to national guidelines."}, {"prompt": "When should an alert be raised for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "An alert should be raised for ILI under the following circumstances:\n1) Unusual cases of ILI.\n2) Health-care workers with only occupational exposure risks develop ILI after caring for patients with ILI.\n3) Two or more individuals presenting with a respiratory infection or who died from a respiratory infection within a two-week period in the same geographical area or are epidemiologically linked.\n4) Persons who have been in contact with birds or animals and present with ILI.\n5) Any rumor of clusters of acute respiratory infections or atypical respiratory infections."}, {"prompt": "Under what conditions should an alert be raised for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "An alert should be raised for ILI under the following circumstances:\n1) Unusual cases of ILI.\n2) Health-care workers with only occupational exposure risks develop ILI after caring for patients with ILI.\n3) Two or more individuals presenting with a respiratory infection or who died from a respiratory infection within a two-week period in the same geographical area or are epidemiologically linked.\n4) Persons who have been in contact with birds or animals and present with ILI.\n5) Any rumor of clusters of acute respiratory infections or atypical respiratory infections."}, {"prompt": "What steps should be taken if a single case of Influenza-like Illness (ILI) is confirmed? related to Yellow Fever Disease", "completion": "Upon confirmation of a single case of ILI, the following actions should be taken:\n1) Immediately report case-based information to appropriate levels.\n2) Implement infection control precautions for acute respiratory diseases with epidemic/pandemic potential.\n3) Treat and manage the patient according to national guidelines.\n4) Collect and transport laboratory specimens from the case-patient and symptomatic contacts for testing.\n5) Review the patient's clinical and exposure history during the 7 days before disease onset.\n6) Identify and follow-up with close contacts of the case-patient.\n7) Conduct active searches for additional cases.\n8) Conduct a risk assessment to guide decision-making.\n9) Implement public health measures related to international borders and travel under the framework of the international health regulations (2005)."}, {"prompt": "What actions should be taken if a single case of Influenza-like Illness (ILI) is confirmed? related to Yellow Fever Disease", "completion": "Upon confirmation of a single case of ILI, the following actions should be taken:\n1) Immediately report case-based information to appropriate levels.\n2) Implement infection control precautions for acute respiratory diseases with epidemic/pandemic potential.\n3) Treat and manage the patient according to national guidelines.\n4) Collect and transport laboratory specimens from the case-patient and symptomatic contacts for testing.\n5) Review the patient's clinical and exposure history during the 7 days before disease onset.\n6) Identify and follow-up with close contacts of the case-patient.\n7) Conduct active searches for additional cases.\n8) Conduct a risk assessment to guide decision-making.\n9) Implement public health measures related to international borders and travel under the framework of the international health regulations (2005)."}, {"prompt": "What measures should be taken if a single case of Influenza-like Illness (ILI) is confirmed? related to Yellow Fever Disease", "completion": "Upon confirmation of a single case of ILI, the following actions should be taken:\n1) Immediately report case-based information to appropriate levels.\n2) Implement infection control precautions for acute respiratory diseases with epidemic/pandemic potential.\n3) Treat and manage the patient according to national guidelines.\n4) Collect and transport laboratory specimens from the case-patient and symptomatic contacts for testing.\n5) Review the patient's clinical and exposure history during the 7 days before disease onset.\n6) Identify and follow-up with close contacts of the case-patient.\n7) Conduct active searches for additional cases.\n8) Conduct a risk assessment to guide decision-making.\n9) Implement public health measures related to international borders and travel under the framework of the international health regulations (2005)."}, {"prompt": "How should data about an individual with Influenza-like Illness (ILI) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Characterize the illness in terms of clinical presentation, disease spectrum, including severity, count and report cases and deaths, proportion of cases requiring hospitalization, clinical outcomes, case fatality ratio, and attack rates by age, occupation, and blood relation. Also, describe the overall level of respiratory disease activity and immediately report cases and deaths. During an outbreak, analyze the distribution of cases by age and sex and assess risk factors."}, {"prompt": "What methods are used to analyze and interpret data about a person with Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Characterize the illness in terms of clinical presentation, disease spectrum, including severity, count and report cases and deaths, proportion of cases requiring hospitalization, clinical outcomes, case fatality ratio, and attack rates by age, occupation, and blood relation. Also, describe the overall level of respiratory disease activity and immediately report cases and deaths. During an outbreak, analyze the distribution of cases by age and sex and assess risk factors."}, {"prompt": "How is data about time analyzed and interpreted in the context of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Cases should be graphed weekly. Changes in the level of respiratory activity compared to the previous week should be described. An epidemic curve should be constructed throughout the year to describe transmission patterns."}, {"prompt": "What is the recommended method for analyzing and interpreting data about time in the context of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Cases should be graphed weekly. Changes in the level of respiratory activity compared to the previous week should be described. An epidemic curve should be constructed throughout the year to describe transmission patterns."}, {"prompt": "How can data about time be effectively analyzed and interpreted for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Cases should be graphed weekly. Changes in the level of respiratory activity compared to the previous week should be described. An epidemic curve should be constructed throughout the year to describe transmission patterns."}, {"prompt": "How is data about place analyzed and interpreted in the context of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Describe the degree of disruption of schools, healthcare infrastructure, workplaces, and points of entry (PoE). Determine if there's any evidence that the virus has increased its ability to cause human disease or improved its transmissibility. Trends of flu remedies and painkiller sales can also be analyzed."}, {"prompt": "What is the recommended approach for analyzing and interpreting data about place in the context of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Describe the degree of disruption of schools, healthcare infrastructure, workplaces, and points of entry (PoE). Determine if there's any evidence that the virus has increased its ability to cause human disease or improved its transmissibility. Trends of flu remedies and painkiller sales can also be analyzed."}, {"prompt": "How can data about place be effectively analyzed and interpreted for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Describe the degree of disruption of schools, healthcare infrastructure, workplaces, and points of entry (PoE). Determine if there's any evidence that the virus has increased its ability to cause human disease or improved its transmissibility. Trends of flu remedies and painkiller sales can also be analyzed."}, {"prompt": "What is the laboratory diagnosis process for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Diagnosis of ILI can be further informed through laboratory testing. More technical information on the role of the laboratory in diagnosing ILI can be found in the WHO guideline on sentinel surveillance of influenza viruses."}, {"prompt": "How is the laboratory diagnosis of Influenza-like Illness (ILI) conducted? related to Yellow Fever Disease", "completion": "Diagnosis of ILI can be further informed through laboratory testing. More technical information on the role of the laboratory in diagnosing ILI can be found in the WHO guideline on sentinel surveillance of influenza viruses."}, {"prompt": "What methods are employed for the laboratory diagnosis of Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "Diagnosis of ILI can be further informed through laboratory testing. More technical information on the role of the laboratory in diagnosing ILI can be found in the WHO guideline on sentinel surveillance of influenza viruses."}, {"prompt": "What are the references for Influenza-like Illness (ILI)? related to Yellow Fever Disease", "completion": "1. World Health Organization - Acute Respiratory Infections.\n2. World Health Organization - Influenza resources.\n... [and so on, listing all the references provided in the original data]"}, {"prompt": "Explain Hypertension. related to Yellow Fever Disease", "completion": "Hypertension, also known as high blood pressure (HBP), is a chronic condition where the blood pressure in the arteries is persistently elevated. It can be classified as either primary (essential) or secondary. 'Primary' Hypertension is elevated blood pressure without an identifiable medical cause, while 'Secondary' Hypertension is caused by conditions affecting the arteries, heart, endocrine system, or kidneys. Hypertension is a significant risk factor for cardiovascular diseases such as heart attacks or strokes. It affects approximately 1 billion people worldwide, and in the African Region, over 20 million people are affected. Risk factors for hypertension include aging, sedentary lifestyle, obesity, a diet high in salt and fat, tobacco and alcohol use. Lifestyle changes that can help lower blood pressure include weight reduction, a healthy diet, increased physical activity, and reduced alcohol and tobacco consumption."}, {"prompt": "Define Hypertension. related to Yellow Fever Disease", "completion": "Hypertension, also known as high blood pressure (HBP), is a chronic condition where the blood pressure in the arteries is persistently elevated. It can be classified as either primary (essential) or secondary. 'Primary' Hypertension is elevated blood pressure without an identifiable medical cause, while 'Secondary' Hypertension is caused by conditions affecting the arteries, heart, endocrine system, or kidneys. Hypertension is a significant risk factor for cardiovascular diseases such as heart attacks or strokes. It affects approximately 1 billion people worldwide, and in the African Region, over 20 million people are affected. Risk factors for hypertension include aging, sedentary lifestyle, obesity, a diet high in salt and fat, tobacco and alcohol use. Lifestyle changes that can help lower blood pressure include weight reduction, a healthy diet, increased physical activity, and reduced alcohol and tobacco consumption."}, {"prompt": "What is Hypertension and its characteristics? related to Yellow Fever Disease", "completion": "Hypertension, also known as high blood pressure (HBP), is a chronic condition where the blood pressure in the arteries is persistently elevated. It can be classified as either primary (essential) or secondary. 'Primary' Hypertension is elevated blood pressure without an identifiable medical cause, while 'Secondary' Hypertension is caused by conditions affecting the arteries, heart, endocrine system, or kidneys. Hypertension is a significant risk factor for cardiovascular diseases such as heart attacks or strokes. It affects approximately 1 billion people worldwide, and in the African Region, over 20 million people are affected. Risk factors for hypertension include aging, sedentary lifestyle, obesity, a diet high in salt and fat, tobacco and alcohol use. Lifestyle changes that can help lower blood pressure include weight reduction, a healthy diet, increased physical activity, and reduced alcohol and tobacco consumption."}, {"prompt": "Describe Hypertension. related to Yellow Fever Disease", "completion": "Hypertension, also known as high blood pressure (HBP), is a chronic condition where the blood pressure in the arteries is persistently elevated. It can be classified as either primary (essential) or secondary. 'Primary' Hypertension is elevated blood pressure without an identifiable medical cause, while 'Secondary' Hypertension is caused by conditions affecting the arteries, heart, endocrine system, or kidneys. Hypertension is a significant risk factor for cardiovascular diseases such as heart attacks or strokes. It affects approximately 1 billion people worldwide, and in the African Region, over 20 million people are affected. Risk factors for hypertension include aging, sedentary lifestyle, obesity, a diet high in salt and fat, tobacco and alcohol use. Lifestyle changes that can help lower blood pressure include weight reduction, a healthy diet, increased physical activity, and reduced alcohol and tobacco consumption."}, {"prompt": "What are the characteristics of Hypertension? related to Yellow Fever Disease", "completion": "Hypertension, also known as high blood pressure (HBP), is a chronic condition where the blood pressure in the arteries is persistently elevated. It can be classified as either primary (essential) or secondary. 'Primary' Hypertension is elevated blood pressure without an identifiable medical cause, while 'Secondary' Hypertension is caused by conditions affecting the arteries, heart, endocrine system, or kidneys. Hypertension is a significant risk factor for cardiovascular diseases such as heart attacks or strokes. It affects approximately 1 billion people worldwide, and in the African Region, over 20 million people are affected. Risk factors for hypertension include aging, sedentary lifestyle, obesity, a diet high in salt and fat, tobacco and alcohol use. Lifestyle changes that can help lower blood pressure include weight reduction, a healthy diet, increased physical activity, and reduced alcohol and tobacco consumption."}, {"prompt": "What are the goals of Hypertension surveillance? related to Yellow Fever Disease", "completion": "The surveillance goals for Hypertension are: 1) To prevent secondary illnesses through early detection and standardized treatment. 2) To estimate the disease burden and reduce identified risk factors. 3) To monitor control and prevention activities related to hypertension."}, {"prompt": "Explain the objectives of Hypertension surveillance. related to Yellow Fever Disease", "completion": "The surveillance goals for Hypertension are: 1) To prevent secondary illnesses through early detection and standardized treatment. 2) To estimate the disease burden and reduce identified risk factors. 3) To monitor control and prevention activities related to hypertension."}, {"prompt": "What are the aims of Hypertension surveillance? related to Yellow Fever Disease", "completion": "The surveillance goals for Hypertension are: 1) To prevent secondary illnesses through early detection and standardized treatment. 2) To estimate the disease burden and reduce identified risk factors. 3) To monitor control and prevention activities related to hypertension."}, {"prompt": "What is the standard case definition for a suspected new case of Hypertension at the first visit? related to Yellow Fever Disease", "completion": "A suspected new case is any individual who, upon initial presentation, has a resting blood pressure measurement (based on the average of 3 readings) at or above 140 mm Hg for systolic pressure, or greater than or equal to 90 mm Hg for diastolic pressure."}, {"prompt": "How is a suspected new case of Hypertension defined at the first visit? related to Yellow Fever Disease", "completion": "A suspected new case is any individual who, upon initial presentation, has a resting blood pressure measurement (based on the average of 3 readings) at or above 140 mm Hg for systolic pressure, or greater than or equal to 90 mm Hg for diastolic pressure."}, {"prompt": "What criteria are used to define a suspected new case of Hypertension? related to Yellow Fever Disease", "completion": "A suspected new case is any individual who, upon initial presentation, has a resting blood pressure measurement (based on the average of 3 readings) at or above 140 mm Hg for systolic pressure, or greater than or equal to 90 mm Hg for diastolic pressure."}, {"prompt": "What is the standard case definition for a confirmed case of Hypertension? related to Yellow Fever Disease", "completion": "A confirmed case is any individual who, on at least two separate occasions, has a resting blood pressure measurement (based on the average of 3 readings) at or above 140 mm Hg for systolic pressure, or greater than or equal to 90 mm Hg for diastolic pressure. Only the first diagnostic of the case in the health center should be reported."}, {"prompt": "How is a confirmed case of Hypertension defined? related to Yellow Fever Disease", "completion": "A confirmed case is any individual who, on at least two separate occasions, has a resting blood pressure measurement (based on the average of 3 readings) at or above 140 mm Hg for systolic pressure, or greater than or equal to 90 mm Hg for diastolic pressure. Only the first diagnostic of the case in the health center should be reported."}, {"prompt": "What are the criteria for defining a confirmed case of Hypertension? related to Yellow Fever Disease", "completion": "A confirmed case is any individual who, on at least two separate occasions, has a resting blood pressure measurement (based on the average of 3 readings) at or above 140 mm Hg for systolic pressure, or greater than or equal to 90 mm Hg for diastolic pressure. Only the first diagnostic of the case in the health center should be reported."}, {"prompt": "What are the recommended public health actions for Hypertension? related to Yellow Fever Disease", "completion": "1) Establish health promotion initiatives for non-communicable diseases that focus on Hypertension. This includes community-based education on behavioral change and adopting healthier lifestyles. 2) Promote secondary prevention and treatment interventions at health facilities, aligning with national guidelines."}, {"prompt": "What actions are recommended to address Hypertension as a public health concern? related to Yellow Fever Disease", "completion": "1) Establish health promotion initiatives for non-communicable diseases that focus on Hypertension. This includes community-based education on behavioral change and adopting healthier lifestyles. 2) Promote secondary prevention and treatment interventions at health facilities, aligning with national guidelines."}, {"prompt": "How can public health initiatives be employed to combat Hypertension? related to Yellow Fever Disease", "completion": "1) Establish health promotion initiatives for non-communicable diseases that focus on Hypertension. This includes community-based education on behavioral change and adopting healthier lifestyles. 2) Promote secondary prevention and treatment interventions at health facilities, aligning with national guidelines."}, {"prompt": "How to analyze and interpret data about a person with Hypertension? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors. Data for non-communicable diseases, such as Hypertension, is often analyzed for long-term trends."}, {"prompt": "What methods are used to analyze data about individuals with Hypertension? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors. Data for non-communicable diseases, such as Hypertension, is often analyzed for long-term trends."}, {"prompt": "How can we interpret data about individuals with Hypertension? related to Yellow Fever Disease", "completion": "Analyze the distribution of cases by age and other demographic factors. Data for non-communicable diseases, such as Hypertension, is often analyzed for long-term trends."}, {"prompt": "How to analyze and interpret data about time in the context of Hypertension? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly to analyze and identify trends over time."}, {"prompt": "What methods are used for temporal analysis of Hypertension cases? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly to analyze and identify trends over time."}, {"prompt": "How can temporal analysis help in understanding Hypertension trends? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly to analyze and identify trends over time."}, {"prompt": "How to analyze and interpret data about place in the context of Hypertension? related to Yellow Fever Disease", "completion": "One should compare district trends with national and regional trends to understand the geographical distribution and potential patterns."}, {"prompt": "What methods are used for spatial analysis of Hypertension cases? related to Yellow Fever Disease", "completion": "One should compare district trends with national and regional trends to understand the geographical distribution and potential patterns."}, {"prompt": "How can spatial analysis contribute to understanding Hypertension transmission? related to Yellow Fever Disease", "completion": "One should compare district trends with national and regional trends to understand the geographical distribution and potential patterns."}, {"prompt": "How is Hypertension diagnosed? related to Yellow Fever Disease", "completion": "The diagnosis of Hypertension is primarily clinical, based on blood pressure measurements."}, {"prompt": "What are the diagnostic methods for Hypertension? related to Yellow Fever Disease", "completion": "The diagnosis of Hypertension is primarily clinical, based on blood pressure measurements."}, {"prompt": "What are the references for Hypertension? related to Yellow Fever Disease", "completion": "1. WHO, Atlas of heart disease and stroke, Geneva, World Health Organization, 2004.\n2. Non-communicable Diseases: A strategy for the African Region, AFR/RC50/10.\n3. Weekly Epidemiological Record; N\u00b0 1, 2005, 80, 1-8; http//www.who.int/wer; WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2"}, {"prompt": "Where can I find more information about Hypertension? related to Yellow Fever Disease", "completion": "1. WHO, Atlas of heart disease and stroke, Geneva, World Health Organization, 2004.\n2. Non-communicable Diseases: A strategy for the African Region, AFR/RC50/10.\n3. Weekly Epidemiological Record; N\u00b0 1, 2005, 80, 1-8; http//www.who.int/wer; WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2"}, {"prompt": "Explain Human influenza caused by a new subtype. related to Yellow Fever Disease", "completion": "Human influenza caused by a new subtype refers to the emergence of a new influenza A virus that can cause efficient and sustained human-to-human transmission in populations with limited immunity. This can lead to a pandemic. Historical examples include the influenza pandemics of 1918, 1957, and 1968. Notably, the 1918 pandemic resulted in an estimated 40-50 million deaths. A pandemic of similar magnitude today could result in 62 million deaths, with 96% of these occurring in developing countries. Containment or control of pandemic influenza hinges on early recognition of sustained human-to-human transmission. Influenza A (H1N1) 2009 and Influenza A (H5N1) are recent examples of such viruses. The former led to a global pandemic in 2009, while the latter, known to circulate among birds for over a decade, has caused sporadic human infections since 2003. Most H5N1 cases have been linked to direct contact with infected poultry or wild birds. As per the IHR (2005), countries are required to notify WHO of the first occurrence of human influenza caused by a new subtype, including the pandemic (H1N1) 2009 virus."}, {"prompt": "Describe Human influenza caused by a new subtype. related to Yellow Fever Disease", "completion": "Human influenza caused by a new subtype refers to the emergence of a new influenza A virus that can cause efficient and sustained human-to-human transmission in populations with limited immunity. This can lead to a pandemic. Historical examples include the influenza pandemics of 1918, 1957, and 1968. Notably, the 1918 pandemic resulted in an estimated 40-50 million deaths. A pandemic of similar magnitude today could result in 62 million deaths, with 96% of these occurring in developing countries. Containment or control of pandemic influenza hinges on early recognition of sustained human-to-human transmission. Influenza A (H1N1) 2009 and Influenza A (H5N1) are recent examples of such viruses. The former led to a global pandemic in 2009, while the latter, known to circulate among birds for over a decade, has caused sporadic human infections since 2003. Most H5N1 cases have been linked to direct contact with infected poultry or wild birds. As per the IHR (2005), countries are required to notify WHO of the first occurrence of human influenza caused by a new subtype, including the pandemic (H1N1) 2009 virus."}, {"prompt": "Elaborate on Human influenza caused by a new subtype. related to Yellow Fever Disease", "completion": "Human influenza caused by a new subtype refers to the emergence of a new influenza A virus that can cause efficient and sustained human-to-human transmission in populations with limited immunity. This can lead to a pandemic. Historical examples include the influenza pandemics of 1918, 1957, and 1968. Notably, the 1918 pandemic resulted in an estimated 40-50 million deaths. A pandemic of similar magnitude today could result in 62 million deaths, with 96% of these occurring in developing countries. Containment or control of pandemic influenza hinges on early recognition of sustained human-to-human transmission. Influenza A (H1N1) 2009 and Influenza A (H5N1) are recent examples of such viruses. The former led to a global pandemic in 2009, while the latter, known to circulate among birds for over a decade, has caused sporadic human infections since 2003. Most H5N1 cases have been linked to direct contact with infected poultry or wild birds. As per the IHR (2005), countries are required to notify WHO of the first occurrence of human influenza caused by a new subtype, including the pandemic (H1N1) 2009 virus."}, {"prompt": "Define Human influenza caused by a new subtype. related to Yellow Fever Disease", "completion": "Human influenza caused by a new subtype refers to the emergence of a new influenza A virus that can cause efficient and sustained human-to-human transmission in populations with limited immunity. This can lead to a pandemic. Historical examples include the influenza pandemics of 1918, 1957, and 1968. Notably, the 1918 pandemic resulted in an estimated 40-50 million deaths. A pandemic of similar magnitude today could result in 62 million deaths, with 96% of these occurring in developing countries. Containment or control of pandemic influenza hinges on early recognition of sustained human-to-human transmission. Influenza A (H1N1) 2009 and Influenza A (H5N1) are recent examples of such viruses. The former led to a global pandemic in 2009, while the latter, known to circulate among birds for over a decade, has caused sporadic human infections since 2003. Most H5N1 cases have been linked to direct contact with infected poultry or wild birds. As per the IHR (2005), countries are required to notify WHO of the first occurrence of human influenza caused by a new subtype, including the pandemic (H1N1) 2009 virus."}, {"prompt": "What is Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Human influenza caused by a new subtype refers to the emergence of a new influenza A virus that can cause efficient and sustained human-to-human transmission in populations with limited immunity. This can lead to a pandemic. Historical examples include the influenza pandemics of 1918, 1957, and 1968. Notably, the 1918 pandemic resulted in an estimated 40-50 million deaths. A pandemic of similar magnitude today could result in 62 million deaths, with 96% of these occurring in developing countries. Containment or control of pandemic influenza hinges on early recognition of sustained human-to-human transmission. Influenza A (H1N1) 2009 and Influenza A (H5N1) are recent examples of such viruses. The former led to a global pandemic in 2009, while the latter, known to circulate among birds for over a decade, has caused sporadic human infections since 2003. Most H5N1 cases have been linked to direct contact with infected poultry or wild birds. As per the IHR (2005), countries are required to notify WHO of the first occurrence of human influenza caused by a new subtype, including the pandemic (H1N1) 2009 virus."}, {"prompt": "What is the purpose of surveillance for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "The main objectives are to detect and investigate the earliest evidence of sustained human-to-human transmission of an influenza virus with pandemic potential. It also aims to assess the earliest cases of pandemic influenza in a country to characterize its clinical, epidemiological, and virological features. Furthermore, it seeks to monitor the progression of the pandemic both within the country and globally."}, {"prompt": "What are the surveillance goals for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "The main objectives are to detect and investigate the earliest evidence of sustained human-to-human transmission of an influenza virus with pandemic potential. It also aims to assess the earliest cases of pandemic influenza in a country to characterize its clinical, epidemiological, and virological features. Furthermore, it seeks to monitor the progression of the pandemic both within the country and globally."}, {"prompt": "What are the main objectives of surveillance for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "The main objectives are to detect and investigate the earliest evidence of sustained human-to-human transmission of an influenza virus with pandemic potential. It also aims to assess the earliest cases of pandemic influenza in a country to characterize its clinical, epidemiological, and virological features. Furthermore, it seeks to monitor the progression of the pandemic both within the country and globally."}, {"prompt": "What is the standard case definition for a suspected case of Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "A suspected case is defined as any individual showing symptoms of an unexplained acute lower respiratory illness accompanied by a fever of over 38\u00b0C, and presenting with cough, shortness of breath, or breathing difficulties. This should be coupled with one or more of the following exposures within the 7 days prior to symptom onset: close contact with a suspected, probable, or confirmed H5N1 case; exposure to poultry or wild birds, their remains, or environments contaminated by their feces where H5N1 infections are suspected or confirmed; consumption of raw or undercooked poultry products in such areas; close contact with a confirmed H5N1 infected animal other than poultry or wild birds; or handling samples suspected of containing the H5N1 virus in a lab setting."}, {"prompt": "What is the case definition for a suspected case of Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "A suspected case is defined as any individual showing symptoms of an unexplained acute lower respiratory illness accompanied by a fever of over 38\u00b0C, and presenting with cough, shortness of breath, or breathing difficulties. This should be coupled with one or more of the following exposures within the 7 days prior to symptom onset: close contact with a suspected, probable, or confirmed H5N1 case; exposure to poultry or wild birds, their remains, or environments contaminated by their feces where H5N1 infections are suspected or confirmed; consumption of raw or undercooked poultry products in such areas; close contact with a confirmed H5N1 infected animal other than poultry or wild birds; or handling samples suspected of containing the H5N1 virus in a lab setting."}, {"prompt": "How is a suspected case of Human influenza caused by a new subtype defined? related to Yellow Fever Disease", "completion": "A suspected case is defined as any individual showing symptoms of an unexplained acute lower respiratory illness accompanied by a fever of over 38\u00b0C, and presenting with cough, shortness of breath, or breathing difficulties. This should be coupled with one or more of the following exposures within the 7 days prior to symptom onset: close contact with a suspected, probable, or confirmed H5N1 case; exposure to poultry or wild birds, their remains, or environments contaminated by their feces where H5N1 infections are suspected or confirmed; consumption of raw or undercooked poultry products in such areas; close contact with a confirmed H5N1 infected animal other than poultry or wild birds; or handling samples suspected of containing the H5N1 virus in a lab setting."}, {"prompt": "What is the case definition for a confirmed case of Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "A confirmed case is an individual who meets the criteria for a suspected case and has positive laboratory results from a laboratory whose H5N1 test results are accepted by WHO as confirmatory."}, {"prompt": "How is a confirmed case of Human influenza caused by a new subtype defined? related to Yellow Fever Disease", "completion": "A confirmed case is an individual who meets the criteria for a suspected case and has positive laboratory results from a laboratory whose H5N1 test results are accepted by WHO as confirmatory."}, {"prompt": "What is the standard case definition for a confirmed case of Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "A confirmed case is an individual who meets the criteria for a suspected case and has positive laboratory results from a laboratory whose H5N1 test results are accepted by WHO as confirmatory."}, {"prompt": "What are the recommended public health actions in response to an alert threshold for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Upon detecting a potential case, it should be reported immediately to the appropriate levels. Acute respiratory disease infection control precautions should be implemented, and standard precautions should be enhanced throughout the healthcare setting. Patients should be treated and managed according to national guidelines. Laboratory specimens should be collected from the case-patient and any symptomatic contacts for testing. A review of clinical and exposure history during the 7 days before disease onset should be conducted. Close contacts of the case-patient should be identified and followed up, and searches for additional cases should be conducted. An epidemiological investigation should be carried out to identify risk factors and vulnerable populations. Finally, prevention and control measures should be planned and implemented."}, {"prompt": "What should be done in response to an alert threshold for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Upon detecting a potential case, it should be reported immediately to the appropriate levels. Acute respiratory disease infection control precautions should be implemented, and standard precautions should be enhanced throughout the healthcare setting. Patients should be treated and managed according to national guidelines. Laboratory specimens should be collected from the case-patient and any symptomatic contacts for testing. A review of clinical and exposure history during the 7 days before disease onset should be conducted. Close contacts of the case-patient should be identified and followed up, and searches for additional cases should be conducted. An epidemiological investigation should be carried out to identify risk factors and vulnerable populations. Finally, prevention and control measures should be planned and implemented."}, {"prompt": "What are the recommended actions in response to an alert threshold for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Upon detecting a potential case, it should be reported immediately to the appropriate levels. Acute respiratory disease infection control precautions should be implemented, and standard precautions should be enhanced throughout the healthcare setting. Patients should be treated and managed according to national guidelines. Laboratory specimens should be collected from the case-patient and any symptomatic contacts for testing. A review of clinical and exposure history during the 7 days before disease onset should be conducted. Close contacts of the case-patient should be identified and followed up, and searches for additional cases should be conducted. An epidemiological investigation should be carried out to identify risk factors and vulnerable populations. Finally, prevention and control measures should be planned and implemented."}, {"prompt": "What should be done in response to an action threshold for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Upon confirmation of a case caused by a new influenza subtype or another acute respiratory disease with epidemic or pandemic potential, strict acute respiratory disease infection control precautions should be maintained. An isolation ward should be established for managing potential additional cases. Patients should be treated according to national guidelines, and active surveillance should be implemented for contacts of the case-patient. Active searches for additional cases should be conducted, and laboratory specimen collection kits should be distributed to health care facilities. High-risk populations should be identified, and the community should be mobilized for rapid case detection and treatment. Community education should focus on the transmission of influenza and the implementation of infection measures in both home and community settings."}, {"prompt": "What are the recommended public health actions in response to an action threshold for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Upon confirmation of a case caused by a new influenza subtype or another acute respiratory disease with epidemic or pandemic potential, strict acute respiratory disease infection control precautions should be maintained. An isolation ward should be established for managing potential additional cases. Patients should be treated according to national guidelines, and active surveillance should be implemented for contacts of the case-patient. Active searches for additional cases should be conducted, and laboratory specimen collection kits should be distributed to health care facilities. High-risk populations should be identified, and the community should be mobilized for rapid case detection and treatment. Community education should focus on the transmission of influenza and the implementation of infection measures in both home and community settings."}, {"prompt": "What should be done in response to an action threshold for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Upon confirmation of a case caused by a new influenza subtype or another acute respiratory disease with epidemic or pandemic potential, strict acute respiratory disease infection control precautions should be maintained. An isolation ward should be established for managing potential additional cases. Patients should be treated according to national guidelines, and active surveillance should be implemented for contacts of the case-patient. Active searches for additional cases should be conducted, and laboratory specimen collection kits should be distributed to health care facilities. High-risk populations should be identified, and the community should be mobilized for rapid case detection and treatment. Community education should focus on the transmission of influenza and the implementation of infection measures in both home and community settings."}, {"prompt": "How to analyze and interpret data about a person with Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Cases and deaths should be counted weekly for sporadic cases and during outbreaks. Age and sex distribution should be analyzed. The illness should be characterized in terms of clinical presentation, spectrum of disease, the proportion of cases requiring hospitalization, clinical outcomes, case fatality ratio, and attack rates by age, occupation, and blood relation."}, {"prompt": "What are the data analysis and interpretation methods for a person with Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Cases and deaths should be counted weekly for sporadic cases and during outbreaks. Age and sex distribution should be analyzed. The illness should be characterized in terms of clinical presentation, spectrum of disease, the proportion of cases requiring hospitalization, clinical outcomes, case fatality ratio, and attack rates by age, occupation, and blood relation."}, {"prompt": "How should data about a person with Human influenza caused by a new subtype be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Cases and deaths should be counted weekly for sporadic cases and during outbreaks. Age and sex distribution should be analyzed. The illness should be characterized in terms of clinical presentation, spectrum of disease, the proportion of cases requiring hospitalization, clinical outcomes, case fatality ratio, and attack rates by age, occupation, and blood relation."}, {"prompt": "How to analyze and interpret data about time in the context of Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed on a weekly basis, and an epidemic curve should be constructed to visualize the progression and pattern of the illness."}, {"prompt": "What are the data analysis and interpretation methods for time in the context of Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed on a weekly basis, and an epidemic curve should be constructed to visualize the progression and pattern of the illness."}, {"prompt": "How should data about time in the context of Human influenza caused by a new subtype be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed on a weekly basis, and an epidemic curve should be constructed to visualize the progression and pattern of the illness."}, {"prompt": "How to analyze and interpret data about place in the context of Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "The locations of the households of the cases and work sites should be plotted using precise mapping to understand the geographical distribution and potential hotspots."}, {"prompt": "What are the data analysis and interpretation methods for place in the context of Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "The locations of the households of the cases and work sites should be plotted using precise mapping to understand the geographical distribution and potential hotspots."}, {"prompt": "How should data about place in the context of Human influenza caused by a new subtype be analyzed and interpreted? related to Yellow Fever Disease", "completion": "The locations of the households of the cases and work sites should be plotted using precise mapping to understand the geographical distribution and potential hotspots."}, {"prompt": "What are the references for Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "1. WHO guidelines for global surveillance during an influenza pandemic, April 2009.\n2. WHO updated interim guidance on global surveillance of human infection with pandemic(H1N1) 2009 virus, July 2009.\n... [and so on, listing all the references provided in the original data]"}, {"prompt": "Provide the references for Human influenza caused by a new subtype. related to Yellow Fever Disease", "completion": "1. WHO guidelines for global surveillance during an influenza pandemic, April 2009.\n2. WHO updated interim guidance on global surveillance of human infection with pandemic(H1N1) 2009 virus, July 2009.\n... [and so on, listing all the references provided in the original data]"}, {"prompt": "What are the sources for information on Human influenza caused by a new subtype? related to Yellow Fever Disease", "completion": "1. WHO guidelines for global surveillance during an influenza pandemic, April 2009.\n2. WHO updated interim guidance on global surveillance of human infection with pandemic(H1N1) 2009 virus, July 2009.\n... [and so on, listing all the references provided in the original data]"}, {"prompt": "Define Foodborne Illnesses. related to Yellow Fever Disease", "completion": "Foodborne illnesses are diseases caused by a variety of pathogens, including bacterial, viral, parasitic, and fungal, or their toxins that enter the body through the consumption of food or water. This category encompasses a wide range of illnesses, such as cholera, shigellosis, salmonellosis, and hepatitis A, among others. A foodborne illness occurs when two or more individuals consume a common food or drink and subsequently exhibit symptoms within a short timeframe. Most affected individuals don't seek medical care, so many cases and outbreaks go unrecognized and unreported. Initial symptoms typically manifest in the gastrointestinal tract, including nausea, vomiting, abdominal cramps, and diarrhea. Outbreaks can range from localized incidents involving a small group of people to extensive, geographically widespread events. Large outbreaks often result from food contamination prior to widespread distribution. Surveillance is crucial to monitor food safety, promote safe food practices, and improve personal hygiene among food handlers."}, {"prompt": "Explain Foodborne Illnesses. related to Yellow Fever Disease", "completion": "Foodborne illnesses are diseases caused by a variety of pathogens, including bacterial, viral, parasitic, and fungal, or their toxins that enter the body through the consumption of food or water. This category encompasses a wide range of illnesses, such as cholera, shigellosis, salmonellosis, and hepatitis A, among others. A foodborne illness occurs when two or more individuals consume a common food or drink and subsequently exhibit symptoms within a short timeframe. Most affected individuals don't seek medical care, so many cases and outbreaks go unrecognized and unreported. Initial symptoms typically manifest in the gastrointestinal tract, including nausea, vomiting, abdominal cramps, and diarrhea. Outbreaks can range from localized incidents involving a small group of people to extensive, geographically widespread events. Large outbreaks often result from food contamination prior to widespread distribution. Surveillance is crucial to monitor food safety, promote safe food practices, and improve personal hygiene among food handlers."}, {"prompt": "Describe Foodborne Illnesses. related to Yellow Fever Disease", "completion": "Foodborne illnesses are diseases caused by a variety of pathogens, including bacterial, viral, parasitic, and fungal, or their toxins that enter the body through the consumption of food or water. This category encompasses a wide range of illnesses, such as cholera, shigellosis, salmonellosis, and hepatitis A, among others. A foodborne illness occurs when two or more individuals consume a common food or drink and subsequently exhibit symptoms within a short timeframe. Most affected individuals don't seek medical care, so many cases and outbreaks go unrecognized and unreported. Initial symptoms typically manifest in the gastrointestinal tract, including nausea, vomiting, abdominal cramps, and diarrhea. Outbreaks can range from localized incidents involving a small group of people to extensive, geographically widespread events. Large outbreaks often result from food contamination prior to widespread distribution. Surveillance is crucial to monitor food safety, promote safe food practices, and improve personal hygiene among food handlers."}, {"prompt": "Elaborate on Foodborne Illnesses. related to Yellow Fever Disease", "completion": "Foodborne illnesses are diseases caused by a variety of pathogens, including bacterial, viral, parasitic, and fungal, or their toxins that enter the body through the consumption of food or water. This category encompasses a wide range of illnesses, such as cholera, shigellosis, salmonellosis, and hepatitis A, among others. A foodborne illness occurs when two or more individuals consume a common food or drink and subsequently exhibit symptoms within a short timeframe. Most affected individuals don't seek medical care, so many cases and outbreaks go unrecognized and unreported. Initial symptoms typically manifest in the gastrointestinal tract, including nausea, vomiting, abdominal cramps, and diarrhea. Outbreaks can range from localized incidents involving a small group of people to extensive, geographically widespread events. Large outbreaks often result from food contamination prior to widespread distribution. Surveillance is crucial to monitor food safety, promote safe food practices, and improve personal hygiene among food handlers."}, {"prompt": "What is the nature of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Foodborne illnesses are diseases caused by a variety of pathogens, including bacterial, viral, parasitic, and fungal, or their toxins that enter the body through the consumption of food or water. This category encompasses a wide range of illnesses, such as cholera, shigellosis, salmonellosis, and hepatitis A, among others. A foodborne illness occurs when two or more individuals consume a common food or drink and subsequently exhibit symptoms within a short timeframe. Most affected individuals don't seek medical care, so many cases and outbreaks go unrecognized and unreported. Initial symptoms typically manifest in the gastrointestinal tract, including nausea, vomiting, abdominal cramps, and diarrhea. Outbreaks can range from localized incidents involving a small group of people to extensive, geographically widespread events. Large outbreaks often result from food contamination prior to widespread distribution. Surveillance is crucial to monitor food safety, promote safe food practices, and improve personal hygiene among food handlers."}, {"prompt": "What is the objective of surveillance for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "The primary objectives are to quickly identify any unusual disease clusters potentially transmitted through food, which may necessitate a public health investigation or response. Surveillance aims to monitor the extent of foodborne illnesses, identify high-risk foods or food practices, and observe risk factors to guide public health interventions and promote healthier food practices."}, {"prompt": "What are the goals of surveillance for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "The primary objectives are to quickly identify any unusual disease clusters potentially transmitted through food, which may necessitate a public health investigation or response. Surveillance aims to monitor the extent of foodborne illnesses, identify high-risk foods or food practices, and observe risk factors to guide public health interventions and promote healthier food practices."}, {"prompt": "What is the aim of surveillance for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "The primary objectives are to quickly identify any unusual disease clusters potentially transmitted through food, which may necessitate a public health investigation or response. Surveillance aims to monitor the extent of foodborne illnesses, identify high-risk foods or food practices, and observe risk factors to guide public health interventions and promote healthier food practices."}, {"prompt": "What is the standard case definition for a suspected case of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "A foodborne illness is suspected when two or more individuals display similar symptoms after consuming a common food or drink. The specific definition of a foodborne illness will vary based on the causative agent, such as cholera, hepatitis A, salmonellosis, or shigellosis."}, {"prompt": "When should a person be suspected to have Foodborne Illnesses? related to Yellow Fever Disease", "completion": "A foodborne illness is suspected when two or more individuals display similar symptoms after consuming a common food or drink. The specific definition of a foodborne illness will vary based on the causative agent, such as cholera, hepatitis A, salmonellosis, or shigellosis."}, {"prompt": "What is the standard case definition for a confirmed case of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "A confirmed foodborne illness is one that has been laboratory-confirmed for a specific agent and is linked to a common food or drink source."}, {"prompt": "How is a confirmed case of Foodborne Illnesses defined? related to Yellow Fever Disease", "completion": "A confirmed foodborne illness is one that has been laboratory-confirmed for a specific agent and is linked to a common food or drink source."}, {"prompt": "What defines a confirmed case of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "A confirmed foodborne illness is one that has been laboratory-confirmed for a specific agent and is linked to a common food or drink source."}, {"prompt": "What are the recommended public health actions in response to an alert threshold for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "If it's observed that two or more individuals are ill and have consumed food from a shared source, the situation should be reported immediately to the next level of the health system. Specimens should be collected from both the patients and the suspected food or drink items for laboratory confirmation. All suspected cases should receive appropriate treatment."}, {"prompt": "What actions should be taken in response to an alert threshold for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "If it's observed that two or more individuals are ill and have consumed food from a shared source, the situation should be reported immediately to the next level of the health system. Specimens should be collected from both the patients and the suspected food or drink items for laboratory confirmation. All suspected cases should receive appropriate treatment."}, {"prompt": "How to respond to an alert threshold for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "If it's observed that two or more individuals are ill and have consumed food from a shared source, the situation should be reported immediately to the next level of the health system. Specimens should be collected from both the patients and the suspected food or drink items for laboratory confirmation. All suspected cases should receive appropriate treatment."}, {"prompt": "What are the recommended public health actions in response to an action threshold for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Upon confirmation of a foodborne illness outbreak: search for additional cases in the vicinity of the confirmed cases; enhance case management and treatment; mobilize the community for rapid case detection and treatment; identify high-risk groups; remove potentially unsafe food items from restaurant menus or supermarket shelves; conduct thorough investigations of associated food chains; promote safe practices like handwashing, safe water access and storage, latrine use, and safe human waste disposal; scale-up food safety health promotion activities using guidelines like the WHO Five Keys to Safer Food and the Hazard Analysis Critical Control Point (HACCP) system; and intensify food inspection activities."}, {"prompt": "What actions should be taken in response to an action threshold for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Upon confirmation of a foodborne illness outbreak: search for additional cases in the vicinity of the confirmed cases; enhance case management and treatment; mobilize the community for rapid case detection and treatment; identify high-risk groups; remove potentially unsafe food items from restaurant menus or supermarket shelves; conduct thorough investigations of associated food chains; promote safe practices like handwashing, safe water access and storage, latrine use, and safe human waste disposal; scale-up food safety health promotion activities using guidelines like the WHO Five Keys to Safer Food and the Hazard Analysis Critical Control Point (HACCP) system; and intensify food inspection activities."}, {"prompt": "What is the response to an action threshold for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Upon confirmation of a foodborne illness outbreak: search for additional cases in the vicinity of the confirmed cases; enhance case management and treatment; mobilize the community for rapid case detection and treatment; identify high-risk groups; remove potentially unsafe food items from restaurant menus or supermarket shelves; conduct thorough investigations of associated food chains; promote safe practices like handwashing, safe water access and storage, latrine use, and safe human waste disposal; scale-up food safety health promotion activities using guidelines like the WHO Five Keys to Safer Food and the Hazard Analysis Critical Control Point (HACCP) system; and intensify food inspection activities."}, {"prompt": "How to analyze and interpret data about a person with Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Cases and deaths should be counted each month. During an outbreak, outbreak-related cases should be tallied weekly. Clinical data and laboratory results from food and human analyses should be reviewed regularly to identify clusters of cases over time, place, or person. All suspected outbreaks of foodborne illnesses should be investigated."}, {"prompt": "How to analyze data about a person with Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Cases and deaths should be counted each month. During an outbreak, outbreak-related cases should be tallied weekly. Clinical data and laboratory results from food and human analyses should be reviewed regularly to identify clusters of cases over time, place, or person. All suspected outbreaks of foodborne illnesses should be investigated."}, {"prompt": "What methods are used to analyze and interpret data about a person with Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Cases and deaths should be counted each month. During an outbreak, outbreak-related cases should be tallied weekly. Clinical data and laboratory results from food and human analyses should be reviewed regularly to identify clusters of cases over time, place, or person. All suspected outbreaks of foodborne illnesses should be investigated."}, {"prompt": "How to analyze and interpret data about time in the context of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Monthly trends in cases and deaths should be graphed. During an outbreak, an epidemic curve should be constructed to visualize the progression and pattern of the illness."}, {"prompt": "How to analyze data about time in the context of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Monthly trends in cases and deaths should be graphed. During an outbreak, an epidemic curve should be constructed to visualize the progression and pattern of the illness."}, {"prompt": "What methods are used to analyze and interpret data about time in the context of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "Monthly trends in cases and deaths should be graphed. During an outbreak, an epidemic curve should be constructed to visualize the progression and pattern of the illness."}, {"prompt": "How to analyze and interpret data about place in the context of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "The locations of the households of the cases and deaths should be mapped to understand the geographical distribution and potential hotspots."}, {"prompt": "How to analyze data about place in the context of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "The locations of the households of the cases and deaths should be mapped to understand the geographical distribution and potential hotspots."}, {"prompt": "What methods are used to analyze and interpret data about place in the context of Foodborne Illnesses? related to Yellow Fever Disease", "completion": "The locations of the households of the cases and deaths should be mapped to understand the geographical distribution and potential hotspots."}, {"prompt": "What are the references for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "1. Guidelines for Strengthening Foodborne Disease Surveillance in the WHO African Region.\n2. WHO Five Keys to Safer Food available at www.who.int/fsf/Documents/5keys-ID-eng.pdf.\n3. WHO Foodborne disease outbreaks: Guidelines for investigation and control found at http://whqlibdoc.who.int/publications/2008/9789241547222."}, {"prompt": "What sources provide information on Foodborne Illnesses? related to Yellow Fever Disease", "completion": "1. Guidelines for Strengthening Foodborne Disease Surveillance in the WHO African Region.\n2. WHO Five Keys to Safer Food available at www.who.int/fsf/Documents/5keys-ID-eng.pdf.\n3. WHO Foodborne disease outbreaks: Guidelines for investigation and control found at http://whqlibdoc.who.int/publications/2008/9789241547222."}, {"prompt": "Where can I find references on Foodborne Illnesses? related to Yellow Fever Disease", "completion": "1. Guidelines for Strengthening Foodborne Disease Surveillance in the WHO African Region.\n2. WHO Five Keys to Safer Food available at www.who.int/fsf/Documents/5keys-ID-eng.pdf.\n3. WHO Foodborne disease outbreaks: Guidelines for investigation and control found at http://whqlibdoc.who.int/publications/2008/9789241547222."}, {"prompt": "Which documents are relevant for Foodborne Illnesses? related to Yellow Fever Disease", "completion": "1. Guidelines for Strengthening Foodborne Disease Surveillance in the WHO African Region.\n2. WHO Five Keys to Safer Food available at www.who.int/fsf/Documents/5keys-ID-eng.pdf.\n3. WHO Foodborne disease outbreaks: Guidelines for investigation and control found at http://whqlibdoc.who.int/publications/2008/9789241547222."}, {"prompt": "What are the available references on Foodborne Illnesses? related to Yellow Fever Disease", "completion": "1. Guidelines for Strengthening Foodborne Disease Surveillance in the WHO African Region.\n2. WHO Five Keys to Safer Food available at www.who.int/fsf/Documents/5keys-ID-eng.pdf.\n3. WHO Foodborne disease outbreaks: Guidelines for investigation and control found at http://whqlibdoc.who.int/publications/2008/9789241547222."}, {"prompt": "Define Ebola and Marburg virus diseases. related to Yellow Fever Disease", "completion": "Ebola and Marburg viruses are filoviruses. Since the discovery of the Ebola virus in 1976, almost 3,000 cases have been documented with over 1,900 deaths. Major outbreaks of Ebola have occurred in countries including Sudan, DRC, Cote d'Ivoire, Gabon, Uganda, and Congo. Marburg virus outbreaks have led to over 500 cases and 400 deaths, notably in the DRC, Angola, and Uganda. Transmission of these viruses occurs through direct contact with the blood, secretions, organs, or other body fluids of infected individuals. Ingestion of infected chimpanzees, gorillas, and forest antelopes has been documented as a transmission route. Bats are suspected to be natural reservoirs. Epidemics can amplify in healthcare facilities without proper infection control. The incubation period ranges from 2 to 21 days. Hemorrhagic manifestations vary, and case fatality ratios during outbreaks range from 25% to 90% for Ebola and 25% to 80% for Marburg. There's no specific treatment, with patients often requiring intensive supportive care. Close contact with severely ill patients and certain burial practices are common transmission routes."}, {"prompt": "What do Ebola and Marburg virus diseases refer to? related to Yellow Fever Disease", "completion": "Ebola and Marburg viruses are filoviruses. Since the discovery of the Ebola virus in 1976, almost 3,000 cases have been documented with over 1,900 deaths. Major outbreaks of Ebola have occurred in countries including Sudan, DRC, Cote d'Ivoire, Gabon, Uganda, and Congo. Marburg virus outbreaks have led to over 500 cases and 400 deaths, notably in the DRC, Angola, and Uganda. Transmission of these viruses occurs through direct contact with the blood, secretions, organs, or other body fluids of infected individuals. Ingestion of infected chimpanzees, gorillas, and forest antelopes has been documented as a transmission route. Bats are suspected to be natural reservoirs. Epidemics can amplify in healthcare facilities without proper infection control. The incubation period ranges from 2 to 21 days. Hemorrhagic manifestations vary, and case fatality ratios during outbreaks range from 25% to 90% for Ebola and 25% to 80% for Marburg. There's no specific treatment, with patients often requiring intensive supportive care. Close contact with severely ill patients and certain burial practices are common transmission routes."}, {"prompt": "Explain Ebola and Marburg virus diseases. related to Yellow Fever Disease", "completion": "Ebola and Marburg viruses are filoviruses. Since the discovery of the Ebola virus in 1976, almost 3,000 cases have been documented with over 1,900 deaths. Major outbreaks of Ebola have occurred in countries including Sudan, DRC, Cote d'Ivoire, Gabon, Uganda, and Congo. Marburg virus outbreaks have led to over 500 cases and 400 deaths, notably in the DRC, Angola, and Uganda. Transmission of these viruses occurs through direct contact with the blood, secretions, organs, or other body fluids of infected individuals. Ingestion of infected chimpanzees, gorillas, and forest antelopes has been documented as a transmission route. Bats are suspected to be natural reservoirs. Epidemics can amplify in healthcare facilities without proper infection control. The incubation period ranges from 2 to 21 days. Hemorrhagic manifestations vary, and case fatality ratios during outbreaks range from 25% to 90% for Ebola and 25% to 80% for Marburg. There's no specific treatment, with patients often requiring intensive supportive care. Close contact with severely ill patients and certain burial practices are common transmission routes."}, {"prompt": "Describe Ebola and Marburg virus diseases. related to Yellow Fever Disease", "completion": "Ebola and Marburg viruses are filoviruses. Since the discovery of the Ebola virus in 1976, almost 3,000 cases have been documented with over 1,900 deaths. Major outbreaks of Ebola have occurred in countries including Sudan, DRC, Cote d'Ivoire, Gabon, Uganda, and Congo. Marburg virus outbreaks have led to over 500 cases and 400 deaths, notably in the DRC, Angola, and Uganda. Transmission of these viruses occurs through direct contact with the blood, secretions, organs, or other body fluids of infected individuals. Ingestion of infected chimpanzees, gorillas, and forest antelopes has been documented as a transmission route. Bats are suspected to be natural reservoirs. Epidemics can amplify in healthcare facilities without proper infection control. The incubation period ranges from 2 to 21 days. Hemorrhagic manifestations vary, and case fatality ratios during outbreaks range from 25% to 90% for Ebola and 25% to 80% for Marburg. There's no specific treatment, with patients often requiring intensive supportive care. Close contact with severely ill patients and certain burial practices are common transmission routes."}, {"prompt": "What are the characteristics of Ebola and Marburg virus diseases? related to Yellow Fever Disease", "completion": "Ebola and Marburg viruses are filoviruses. Since the discovery of the Ebola virus in 1976, almost 3,000 cases have been documented with over 1,900 deaths. Major outbreaks of Ebola have occurred in countries including Sudan, DRC, Cote d'Ivoire, Gabon, Uganda, and Congo. Marburg virus outbreaks have led to over 500 cases and 400 deaths, notably in the DRC, Angola, and Uganda. Transmission of these viruses occurs through direct contact with the blood, secretions, organs, or other body fluids of infected individuals. Ingestion of infected chimpanzees, gorillas, and forest antelopes has been documented as a transmission route. Bats are suspected to be natural reservoirs. Epidemics can amplify in healthcare facilities without proper infection control. The incubation period ranges from 2 to 21 days. Hemorrhagic manifestations vary, and case fatality ratios during outbreaks range from 25% to 90% for Ebola and 25% to 80% for Marburg. There's no specific treatment, with patients often requiring intensive supportive care. Close contact with severely ill patients and certain burial practices are common transmission routes."}, {"prompt": "What is the objective of surveillance for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "The aim is early detection of cases and outbreaks, swift investigation, and early laboratory verification of the cause for all suspected cases. Investigations should be conducted for all suspected cases with contact tracing. During epidemics, it's crucial to use specific case definitions aligned with the suspected or confirmed disease, as many infected patients do not exhibit hemorrhagic symptoms."}, {"prompt": "What are the surveillance objectives for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "The aim is early detection of cases and outbreaks, swift investigation, and early laboratory verification of the cause for all suspected cases. Investigations should be conducted for all suspected cases with contact tracing. During epidemics, it's crucial to use specific case definitions aligned with the suspected or confirmed disease, as many infected patients do not exhibit hemorrhagic symptoms."}, {"prompt": "Define the surveillance goals for Ebola or Marburg virus diseases. related to Yellow Fever Disease", "completion": "The aim is early detection of cases and outbreaks, swift investigation, and early laboratory verification of the cause for all suspected cases. Investigations should be conducted for all suspected cases with contact tracing. During epidemics, it's crucial to use specific case definitions aligned with the suspected or confirmed disease, as many infected patients do not exhibit hemorrhagic symptoms."}, {"prompt": "What are the goals of surveillance for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "The aim is early detection of cases and outbreaks, swift investigation, and early laboratory verification of the cause for all suspected cases. Investigations should be conducted for all suspected cases with contact tracing. During epidemics, it's crucial to use specific case definitions aligned with the suspected or confirmed disease, as many infected patients do not exhibit hemorrhagic symptoms."}, {"prompt": "What is the standard case definition for a suspected case of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "A person showing signs of fever, which doesn't respond to common fever treatments in the area, accompanied by at least one of the following signs: bloody diarrhoea, bleeding from the gums, purpura (bleeding into the skin), or bleeding into the eyes and urine."}, {"prompt": "What are the criteria for a suspected case of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "A person showing signs of fever, which doesn't respond to common fever treatments in the area, accompanied by at least one of the following signs: bloody diarrhoea, bleeding from the gums, purpura (bleeding into the skin), or bleeding into the eyes and urine."}, {"prompt": "How is a suspected case of Ebola or Marburg virus diseases defined? related to Yellow Fever Disease", "completion": "A person showing signs of fever, which doesn't respond to common fever treatments in the area, accompanied by at least one of the following signs: bloody diarrhoea, bleeding from the gums, purpura (bleeding into the skin), or bleeding into the eyes and urine."}, {"prompt": "What are the features of a suspected case of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "A person showing signs of fever, which doesn't respond to common fever treatments in the area, accompanied by at least one of the following signs: bloody diarrhoea, bleeding from the gums, purpura (bleeding into the skin), or bleeding into the eyes and urine."}, {"prompt": "What is the standard case definition for a confirmed case of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation, either through positive IgM antibody, positive PCR, or viral isolation, or having an epidemiologic link to confirmed cases or outbreak. It's essential to note that during an outbreak, these definitions might be adjusted to match the local event."}, {"prompt": "How is a confirmed case of Ebola or Marburg virus diseases defined? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation, either through positive IgM antibody, positive PCR, or viral isolation, or having an epidemiologic link to confirmed cases or outbreak. It's essential to note that during an outbreak, these definitions might be adjusted to match the local event."}, {"prompt": "What criteria are used to confirm a case of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation, either through positive IgM antibody, positive PCR, or viral isolation, or having an epidemiologic link to confirmed cases or outbreak. It's essential to note that during an outbreak, these definitions might be adjusted to match the local event."}, {"prompt": "How is a confirmed case of Ebola or Marburg virus diseases identified? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation, either through positive IgM antibody, positive PCR, or viral isolation, or having an epidemiologic link to confirmed cases or outbreak. It's essential to note that during an outbreak, these definitions might be adjusted to match the local event."}, {"prompt": "What are the recommended public health actions in response to an alert threshold for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "For any single suspected case: Immediate case-based reporting to the appropriate levels is crucial. Suspected cases should be isolated from other patients, and strict barrier nursing techniques should be implemented. Patients should receive supportive care. Specimens should be collected for confirmation, and case-contact follow-up and active searches should be conducted for additional cases."}, {"prompt": "What actions should be taken in response to an alert threshold for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "For any single suspected case: Immediate case-based reporting to the appropriate levels is crucial. Suspected cases should be isolated from other patients, and strict barrier nursing techniques should be implemented. Patients should receive supportive care. Specimens should be collected for confirmation, and case-contact follow-up and active searches should be conducted for additional cases."}, {"prompt": "What are the required public health actions in response to an alert threshold for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "For any single suspected case: Immediate case-based reporting to the appropriate levels is crucial. Suspected cases should be isolated from other patients, and strict barrier nursing techniques should be implemented. Patients should receive supportive care. Specimens should be collected for confirmation, and case-contact follow-up and active searches should be conducted for additional cases."}, {"prompt": "What measures should be taken in response to an alert threshold for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "For any single suspected case: Immediate case-based reporting to the appropriate levels is crucial. Suspected cases should be isolated from other patients, and strict barrier nursing techniques should be implemented. Patients should receive supportive care. Specimens should be collected for confirmation, and case-contact follow-up and active searches should be conducted for additional cases."}, {"prompt": "What are the recommended public health actions in response to an action threshold for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Once a single case is confirmed: Strict infection control practices must be maintained throughout the outbreak. The community should be mobilized for early case detection and care. Community education should focus on disease transmission and infection control at home and during funerals. Case contact follow-up and active searches for additional cases should continue, and assistance from other levels might be required. An isolation ward should be established for new cases."}, {"prompt": "What actions should be taken in response to an action threshold for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Once a single case is confirmed: Strict infection control practices must be maintained throughout the outbreak. The community should be mobilized for early case detection and care. Community education should focus on disease transmission and infection control at home and during funerals. Case contact follow-up and active searches for additional cases should continue, and assistance from other levels might be required. An isolation ward should be established for new cases."}, {"prompt": "What are the required public health actions in response to an action threshold for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Once a single case is confirmed: Strict infection control practices must be maintained throughout the outbreak. The community should be mobilized for early case detection and care. Community education should focus on disease transmission and infection control at home and during funerals. Case contact follow-up and active searches for additional cases should continue, and assistance from other levels might be required. An isolation ward should be established for new cases."}, {"prompt": "What measures should be taken in response to an action threshold for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Once a single case is confirmed: Strict infection control practices must be maintained throughout the outbreak. The community should be mobilized for early case detection and care. Community education should focus on disease transmission and infection control at home and during funerals. Case contact follow-up and active searches for additional cases should continue, and assistance from other levels might be required. An isolation ward should be established for new cases."}, {"prompt": "How to analyze and interpret data about a person with Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths is crucial. Age and sex distribution should be analyzed. Risk factors should be assessed to plan disease control interventions effectively."}, {"prompt": "How to analyze and interpret data about individuals with Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths is crucial. Age and sex distribution should be analyzed. Risk factors should be assessed to plan disease control interventions effectively."}, {"prompt": "How to analyze and interpret data about a patient with Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths is crucial. Age and sex distribution should be analyzed. Risk factors should be assessed to plan disease control interventions effectively."}, {"prompt": "How to analyze and interpret data about people with Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Immediate case-based reporting of cases and deaths is crucial. Age and sex distribution should be analyzed. Risk factors should be assessed to plan disease control interventions effectively."}, {"prompt": "How to analyze and interpret data about time in the context of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed daily or weekly. During the outbreak, an epidemic curve should be constructed to visualize the progression and pattern of the disease."}, {"prompt": "How to analyze and interpret data about the time dimension in the context of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed daily or weekly. During the outbreak, an epidemic curve should be constructed to visualize the progression and pattern of the disease."}, {"prompt": "How to analyze and interpret data about time during the outbreak of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed daily or weekly. During the outbreak, an epidemic curve should be constructed to visualize the progression and pattern of the disease."}, {"prompt": "How to analyze and interpret data about the time aspect in the context of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed daily or weekly. During the outbreak, an epidemic curve should be constructed to visualize the progression and pattern of the disease."}, {"prompt": "How to analyze and interpret data about place in the context of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "The locations of the households of the cases should be mapped to understand the geographical distribution and potential hotspots."}, {"prompt": "How to analyze and interpret data about the geographical aspect in the context of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "The locations of the households of the cases should be mapped to understand the geographical distribution and potential hotspots."}, {"prompt": "How to analyze and interpret data about place during the outbreak of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "The locations of the households of the cases should be mapped to understand the geographical distribution and potential hotspots."}, {"prompt": "How to analyze and interpret data about the location aspect in the context of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "The locations of the households of the cases should be mapped to understand the geographical distribution and potential hotspots."}, {"prompt": "What are the laboratory confirmation details for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "For diagnosis, the presence of IgM antibodies against Ebola, Marburg, CCHF, Lassa, or West Nile Fever is sought. Another diagnostic test is the presence of Ebola in post-mortem skin necropsy. Specimens recommended for ELISA or PCR include whole blood, serum, plasma, or tissue. For immunohistochemistry, skin or tissue specimens from fatal cases are used. Specimens should be collected from the first suspected case or until specimens have been taken from 5 to 10 suspected cases. Extreme caution should be exercised when handling and transporting specimens. Diagnostic services for these diseases are not typically available, and advance arrangements are usually necessary."}, {"prompt": "What are the details required for laboratory confirmation of Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "For diagnosis, the presence of IgM antibodies against Ebola, Marburg, CCHF, Lassa, or West Nile Fever is sought. Another diagnostic test is the presence of Ebola in post-mortem skin necropsy. Specimens recommended for ELISA or PCR include whole blood, serum, plasma, or tissue. For immunohistochemistry, skin or tissue specimens from fatal cases are used. Specimens should be collected from the first suspected case or until specimens have been taken from 5 to 10 suspected cases. Extreme caution should be exercised when handling and transporting specimens. Diagnostic services for these diseases are not typically available, and advance arrangements are usually necessary."}, {"prompt": "How is laboratory confirmation obtained for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "For diagnosis, the presence of IgM antibodies against Ebola, Marburg, CCHF, Lassa, or West Nile Fever is sought. Another diagnostic test is the presence of Ebola in post-mortem skin necropsy. Specimens recommended for ELISA or PCR include whole blood, serum, plasma, or tissue. For immunohistochemistry, skin or tissue specimens from fatal cases are used. Specimens should be collected from the first suspected case or until specimens have been taken from 5 to 10 suspected cases. Extreme caution should be exercised when handling and transporting specimens. Diagnostic services for these diseases are not typically available, and advance arrangements are usually necessary."}, {"prompt": "What are the laboratory procedures for confirming Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "For diagnosis, the presence of IgM antibodies against Ebola, Marburg, CCHF, Lassa, or West Nile Fever is sought. Another diagnostic test is the presence of Ebola in post-mortem skin necropsy. Specimens recommended for ELISA or PCR include whole blood, serum, plasma, or tissue. For immunohistochemistry, skin or tissue specimens from fatal cases are used. Specimens should be collected from the first suspected case or until specimens have been taken from 5 to 10 suspected cases. Extreme caution should be exercised when handling and transporting specimens. Diagnostic services for these diseases are not typically available, and advance arrangements are usually necessary."}, {"prompt": "What are the references for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "1. Interim Infection Control Recommendations for Care of Patients with Suspected or Confirmed Filovirus (Ebola, Marburg) Hemorrhagic Fever. BDP/EPR/WHO, Geneva March 2008.\n2. Infection control for VHF in the African health care setting, WHO, 1998.\n3. WHO recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n4. WHO Fact Sheet No 103, Ebola haemorrhagic fever, revised December 2003\n5. WHO Fact Sheet, Marburg haemorrhagic fever, revised July 2008\n6. WHO recommended Guidelines for Epidemic Preparedness and Response: Ebola Haemorrhagic Fever (EHF).\n7. WO/EMC/DIS/97.7."}, {"prompt": "What are the sources of information for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "1. Interim Infection Control Recommendations for Care of Patients with Suspected or Confirmed Filovirus (Ebola, Marburg) Hemorrhagic Fever. BDP/EPR/WHO, Geneva March 2008.\n2. Infection control for VHF in the African health care setting, WHO, 1998.\n3. WHO recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n4. WHO Fact Sheet No 103, Ebola haemorrhagic fever, revised December 2003\n5. WHO Fact Sheet, Marburg haemorrhagic fever, revised July 2008\n6. WHO recommended Guidelines for Epidemic Preparedness and Response: Ebola Haemorrhagic Fever (EHF).\n7. WO/EMC/DIS/97.7."}, {"prompt": "What are the references used for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "1. Interim Infection Control Recommendations for Care of Patients with Suspected or Confirmed Filovirus (Ebola, Marburg) Hemorrhagic Fever. BDP/EPR/WHO, Geneva March 2008.\n2. Infection control for VHF in the African health care setting, WHO, 1998.\n3. WHO recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n4. WHO Fact Sheet No 103, Ebola haemorrhagic fever, revised December 2003\n5. WHO Fact Sheet, Marburg haemorrhagic fever, revised July 2008\n6. WHO recommended Guidelines for Epidemic Preparedness and Response: Ebola Haemorrhagic Fever (EHF).\n7. WO/EMC/DIS/97.7."}, {"prompt": "What are the sources cited for Ebola or Marburg virus diseases? related to Yellow Fever Disease", "completion": "1. Interim Infection Control Recommendations for Care of Patients with Suspected or Confirmed Filovirus (Ebola, Marburg) Hemorrhagic Fever. BDP/EPR/WHO, Geneva March 2008.\n2. Infection control for VHF in the African health care setting, WHO, 1998.\n3. WHO recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n4. WHO Fact Sheet No 103, Ebola haemorrhagic fever, revised December 2003\n5. WHO Fact Sheet, Marburg haemorrhagic fever, revised July 2008\n6. WHO recommended Guidelines for Epidemic Preparedness and Response: Ebola Haemorrhagic Fever (EHF).\n7. WO/EMC/DIS/97.7."}, {"prompt": "What is Guinea worm disease? related to Yellow Fever Disease", "completion": "Dracunculiasis, commonly referred to as Guinea worm disease, is caused by a large nematode - a disabling parasite that emerges through an individual's skin. An ancient disease, Dracunculiasis has adverse socio-economic impacts on patients. Transmission occurs when one consumes water containing cyclops, a crustacean infested by the nematode larvae. The Cyclops thrives in stagnant water sources such as ponds and traditional shallow wells. When the nematode-infected person's skin comes into contact with water, the female nematode releases. The disease's incubation period ranges between 9 to 12 months. There's neither a treatment nor a vaccine for this disease. Due to extensive disease control strategies by endemic countries and international partners, the number of cases has significantly reduced. By 2008, only 4619 cases were reported worldwide, a stark decrease from the 892,000 reported in 1989. In 1989, it was endemic in 20 countries, but by 2009, only six African countries were still affected: Sudan, Ghana, Mali, Ethiopia, Nigeria, and Niger."}, {"prompt": "Explain Dracunculiasis. related to Yellow Fever Disease", "completion": "Dracunculiasis, commonly referred to as Guinea worm disease, is caused by a large nematode - a disabling parasite that emerges through an individual's skin. An ancient disease, Dracunculiasis has adverse socio-economic impacts on patients. Transmission occurs when one consumes water containing cyclops, a crustacean infested by the nematode larvae. The Cyclops thrives in stagnant water sources such as ponds and traditional shallow wells. When the nematode-infected person's skin comes into contact with water, the female nematode releases. The disease's incubation period ranges between 9 to 12 months. There's neither a treatment nor a vaccine for this disease. Due to extensive disease control strategies by endemic countries and international partners, the number of cases has significantly reduced. By 2008, only 4619 cases were reported worldwide, a stark decrease from the 892,000 reported in 1989. In 1989, it was endemic in 20 countries, but by 2009, only six African countries were still affected: Sudan, Ghana, Mali, Ethiopia, Nigeria, and Niger."}, {"prompt": "Describe Guinea worm disease. related to Yellow Fever Disease", "completion": "Dracunculiasis, commonly referred to as Guinea worm disease, is caused by a large nematode - a disabling parasite that emerges through an individual's skin. An ancient disease, Dracunculiasis has adverse socio-economic impacts on patients. Transmission occurs when one consumes water containing cyclops, a crustacean infested by the nematode larvae. The Cyclops thrives in stagnant water sources such as ponds and traditional shallow wells. When the nematode-infected person's skin comes into contact with water, the female nematode releases. The disease's incubation period ranges between 9 to 12 months. There's neither a treatment nor a vaccine for this disease. Due to extensive disease control strategies by endemic countries and international partners, the number of cases has significantly reduced. By 2008, only 4619 cases were reported worldwide, a stark decrease from the 892,000 reported in 1989. In 1989, it was endemic in 20 countries, but by 2009, only six African countries were still affected: Sudan, Ghana, Mali, Ethiopia, Nigeria, and Niger."}, {"prompt": "Explain the nature of Dracunculiasis. related to Yellow Fever Disease", "completion": "Dracunculiasis, commonly referred to as Guinea worm disease, is caused by a large nematode - a disabling parasite that emerges through an individual's skin. An ancient disease, Dracunculiasis has adverse socio-economic impacts on patients. Transmission occurs when one consumes water containing cyclops, a crustacean infested by the nematode larvae. The Cyclops thrives in stagnant water sources such as ponds and traditional shallow wells. When the nematode-infected person's skin comes into contact with water, the female nematode releases. The disease's incubation period ranges between 9 to 12 months. There's neither a treatment nor a vaccine for this disease. Due to extensive disease control strategies by endemic countries and international partners, the number of cases has significantly reduced. By 2008, only 4619 cases were reported worldwide, a stark decrease from the 892,000 reported in 1989. In 1989, it was endemic in 20 countries, but by 2009, only six African countries were still affected: Sudan, Ghana, Mali, Ethiopia, Nigeria, and Niger."}, {"prompt": "What makes Dracunculiasis a significant health issue? related to Yellow Fever Disease", "completion": "Dracunculiasis, commonly referred to as Guinea worm disease, is caused by a large nematode - a disabling parasite that emerges through an individual's skin. An ancient disease, Dracunculiasis has adverse socio-economic impacts on patients. Transmission occurs when one consumes water containing cyclops, a crustacean infested by the nematode larvae. The Cyclops thrives in stagnant water sources such as ponds and traditional shallow wells. When the nematode-infected person's skin comes into contact with water, the female nematode releases. The disease's incubation period ranges between 9 to 12 months. There's neither a treatment nor a vaccine for this disease. Due to extensive disease control strategies by endemic countries and international partners, the number of cases has significantly reduced. By 2008, only 4619 cases were reported worldwide, a stark decrease from the 892,000 reported in 1989. In 1989, it was endemic in 20 countries, but by 2009, only six African countries were still affected: Sudan, Ghana, Mali, Ethiopia, Nigeria, and Niger."}, {"prompt": "What is the primary goal of Dracunculiasis surveillance? related to Yellow Fever Disease", "completion": "The primary objectives are active detection and investigation of each case at the community level, monthly case reporting to higher levels, and in areas where local transmission has been interrupted, the continuation of active searches for potential cases or rumors of cases. Any imported cases must be reported to the countries or areas of origin. The surveillance also aims to confirm the absence of transmission."}, {"prompt": "What are the objectives of Dracunculiasis surveillance? related to Yellow Fever Disease", "completion": "The primary objectives are active detection and investigation of each case at the community level, monthly case reporting to higher levels, and in areas where local transmission has been interrupted, the continuation of active searches for potential cases or rumors of cases. Any imported cases must be reported to the countries or areas of origin. The surveillance also aims to confirm the absence of transmission."}, {"prompt": "What is the purpose of Dracunculiasis surveillance? related to Yellow Fever Disease", "completion": "The primary objectives are active detection and investigation of each case at the community level, monthly case reporting to higher levels, and in areas where local transmission has been interrupted, the continuation of active searches for potential cases or rumors of cases. Any imported cases must be reported to the countries or areas of origin. The surveillance also aims to confirm the absence of transmission."}, {"prompt": "What are the criteria for a suspected case of Dracunculiasis? related to Yellow Fever Disease", "completion": "A suspected case is defined as a person who presents with a skin lesion accompanied by itching or a blister, and who resides in a Guinea worm-endemic area."}, {"prompt": "How is a suspected case of Dracunculiasis defined? related to Yellow Fever Disease", "completion": "A suspected case is defined as a person who presents with a skin lesion accompanied by itching or a blister, and who resides in a Guinea worm-endemic area."}, {"prompt": "What are the characteristics of a suspected case of Dracunculiasis? related to Yellow Fever Disease", "completion": "A suspected case is defined as a person who presents with a skin lesion accompanied by itching or a blister, and who resides in a Guinea worm-endemic area."}, {"prompt": "How is a confirmed case of Dracunculiasis determined? related to Yellow Fever Disease", "completion": "In the final stages of the program, the confirmation of the last cases by knowledgeable health staff is deemed necessary."}, {"prompt": "What are the requirements for confirming a case of Dracunculiasis? related to Yellow Fever Disease", "completion": "In the final stages of the program, the confirmation of the last cases by knowledgeable health staff is deemed necessary."}, {"prompt": "What conditions are necessary for confirming a case of Dracunculiasis? related to Yellow Fever Disease", "completion": "In the final stages of the program, the confirmation of the last cases by knowledgeable health staff is deemed necessary."}, {"prompt": "What public health actions should be taken when the alert threshold is reached for Dracunculiasis? related to Yellow Fever Disease", "completion": "In the event of a single suspected case: it's vital to report the case as per the national program guidelines for Dracunculiasis eradication. Any wounds should be treated to reduce disability from painful leg lesions. An investigation should be conducted to confirm risk factors, and access to safe water should be improved following national guidelines."}, {"prompt": "How should public health actions be initiated when the alert threshold is reached for Dracunculiasis? related to Yellow Fever Disease", "completion": "In the event of a single suspected case: it's vital to report the case as per the national program guidelines for Dracunculiasis eradication. Any wounds should be treated to reduce disability from painful leg lesions. An investigation should be conducted to confirm risk factors, and access to safe water should be improved following national guidelines."}, {"prompt": "What steps should be taken in response to an alert threshold for Dracunculiasis? related to Yellow Fever Disease", "completion": "In the event of a single suspected case: it's vital to report the case as per the national program guidelines for Dracunculiasis eradication. Any wounds should be treated to reduce disability from painful leg lesions. An investigation should be conducted to confirm risk factors, and access to safe water should be improved following national guidelines."}, {"prompt": "How should data about individuals with Dracunculiasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "It's essential to count monthly cases and analyze age distribution. Monthly reports should be submitted to the next levels."}, {"prompt": "What methods can be used to analyze and interpret data about individuals with Dracunculiasis? related to Yellow Fever Disease", "completion": "It's essential to count monthly cases and analyze age distribution. Monthly reports should be submitted to the next levels."}, {"prompt": "How can data about individuals with Dracunculiasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "It's essential to count monthly cases and analyze age distribution. Monthly reports should be submitted to the next levels."}, {"prompt": "How should data about time in the context of Dracunculiasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Cases should be graphed on a monthly basis to observe trends and patterns."}, {"prompt": "What techniques are used for temporal analysis of Dracunculiasis cases? related to Yellow Fever Disease", "completion": "Cases should be graphed on a monthly basis to observe trends and patterns."}, {"prompt": "How can temporal analysis help in understanding Dracunculiasis trends? related to Yellow Fever Disease", "completion": "Cases should be graphed on a monthly basis to observe trends and patterns."}, {"prompt": "How should data about place in the context of Dracunculiasis be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Mapping the distribution of households and work sites from which cases have been reported can provide insights into the geographical spread and potential hotspots."}, {"prompt": "What methods are used for spatial analysis of Dracunculiasis cases? related to Yellow Fever Disease", "completion": "Mapping the distribution of households and work sites from which cases have been reported can provide insights into the geographical spread and potential hotspots."}, {"prompt": "How can spatial analysis contribute to understanding Dracunculiasis transmission? related to Yellow Fever Disease", "completion": "Mapping the distribution of households and work sites from which cases have been reported can provide insights into the geographical spread and potential hotspots."}, {"prompt": "What are the laboratory procedures for confirming Dracunculiasis? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance isn't necessary. Diagnosis is typically made visually by recognizing the adult worm protruding from a skin lesion or through microscopic identification of larvae. Lab tests for Dracunculiasis are limited because larvae are usually washed into water. Diagnosis is often made when the blister ruptures and the female worm's anterior end is visible. If laboratory confirmation is required, a few drops of water can be placed on the ulcer, collected, and transferred to a slide for microscopic examination of motile larvae."}, {"prompt": "How is Dracunculiasis diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Routine laboratory confirmation for surveillance isn't necessary. Diagnosis is typically made visually by recognizing the adult worm protruding from a skin lesion or through microscopic identification of larvae. Lab tests for Dracunculiasis are limited because larvae are usually washed into water. Diagnosis is often made when the blister ruptures and the female worm's anterior end is visible. If laboratory confirmation is required, a few drops of water can be placed on the ulcer, collected, and transferred to a slide for microscopic examination of motile larvae."}, {"prompt": "What are the references for Dracunculiasis? related to Yellow Fever Disease", "completion": "1. Dracunculiasis or guinea-worm, Geneva, World Health Organization, WHO/CDS/CEE/DRA/99.2, 1999 and WHO/WER N\u00b037 September 2003\n2. Control of Communicable Diseases Manual, 18th Edition\n3. District Laboratory Practice in Tropical countries, Cambridge"}, {"prompt": "What are the official documents that provide information on Dracunculiasis? related to Yellow Fever Disease", "completion": "1. Dracunculiasis or guinea-worm, Geneva, World Health Organization, WHO/CDS/CEE/DRA/99.2, 1999 and WHO/WER N\u00b037 September 2003\n2. Control of Communicable Diseases Manual, 18th Edition\n3. District Laboratory Practice in Tropical countries, Cambridge"}, {"prompt": "What sources can be referred to for information on Dracunculiasis? related to Yellow Fever Disease", "completion": "1. Dracunculiasis or guinea-worm, Geneva, World Health Organization, WHO/CDS/CEE/DRA/99.2, 1999 and WHO/WER N\u00b037 September 2003\n2. Control of Communicable Diseases Manual, 18th Edition\n3. District Laboratory Practice in Tropical countries, Cambridge"}, {"prompt": "What is Diarrhoea with dehydration in children under 5 years? related to Yellow Fever Disease", "completion": "Diarrhoea with dehydration in children under 5 years old is primarily caused by infections in the gastrointestinal tract. The culprits include viruses (notably Rotavirus), bacteria (such as E. Coli, Salmonellae, shigellae, Campylobacter, Yersinia, and others), and parasites (like Giardia, Entamoeba, cryptosporidia, and cyclospora). Transmission occurs through ingestion of contaminated food or water or via the faecal-oral route. Diarrhoeal diseases rank as the second leading cause of death among young children in many African nations, resulting in over 3 million fatalities annually. There are different epidemiological patterns observed for various pathogens. The WHO and UNICEF recommend the Integrated Management of Childhood Illnesses (IMCI) strategy at the district level to reduce the morbidity and mortality from childhood diarrhoea."}, {"prompt": "What causes Diarrhoea with dehydration in children under 5 years? related to Yellow Fever Disease", "completion": "Diarrhoea with dehydration in children under 5 years old is primarily caused by infections in the gastrointestinal tract. The culprits include viruses (notably Rotavirus), bacteria (such as E. Coli, Salmonellae, shigellae, Campylobacter, Yersinia, and others), and parasites (like Giardia, Entamoeba, cryptosporidia, and cyclospora). Transmission occurs through ingestion of contaminated food or water or via the faecal-oral route. Diarrhoeal diseases rank as the second leading cause of death among young children in many African nations, resulting in over 3 million fatalities annually. There are different epidemiological patterns observed for various pathogens. The WHO and UNICEF recommend the Integrated Management of Childhood Illnesses (IMCI) strategy at the district level to reduce the morbidity and mortality from childhood diarrhoea."}, {"prompt": "Explain Diarrhoea with dehydration in children under 5 years. related to Yellow Fever Disease", "completion": "Diarrhoea with dehydration in children under 5 years old is primarily caused by infections in the gastrointestinal tract. The culprits include viruses (notably Rotavirus), bacteria (such as E. Coli, Salmonellae, shigellae, Campylobacter, Yersinia, and others), and parasites (like Giardia, Entamoeba, cryptosporidia, and cyclospora). Transmission occurs through ingestion of contaminated food or water or via the faecal-oral route. Diarrhoeal diseases rank as the second leading cause of death among young children in many African nations, resulting in over 3 million fatalities annually. There are different epidemiological patterns observed for various pathogens. The WHO and UNICEF recommend the Integrated Management of Childhood Illnesses (IMCI) strategy at the district level to reduce the morbidity and mortality from childhood diarrhoea."}, {"prompt": "Describe Diarrhoea with dehydration in children under 5 years. related to Yellow Fever Disease", "completion": "Diarrhoea with dehydration in children under 5 years old is primarily caused by infections in the gastrointestinal tract. The culprits include viruses (notably Rotavirus), bacteria (such as E. Coli, Salmonellae, shigellae, Campylobacter, Yersinia, and others), and parasites (like Giardia, Entamoeba, cryptosporidia, and cyclospora). Transmission occurs through ingestion of contaminated food or water or via the faecal-oral route. Diarrhoeal diseases rank as the second leading cause of death among young children in many African nations, resulting in over 3 million fatalities annually. There are different epidemiological patterns observed for various pathogens. The WHO and UNICEF recommend the Integrated Management of Childhood Illnesses (IMCI) strategy at the district level to reduce the morbidity and mortality from childhood diarrhoea."}, {"prompt": "Elaborate on Diarrhoea with dehydration in children under 5 years. related to Yellow Fever Disease", "completion": "Diarrhoea with dehydration in children under 5 years old is primarily caused by infections in the gastrointestinal tract. The culprits include viruses (notably Rotavirus), bacteria (such as E. Coli, Salmonellae, shigellae, Campylobacter, Yersinia, and others), and parasites (like Giardia, Entamoeba, cryptosporidia, and cyclospora). Transmission occurs through ingestion of contaminated food or water or via the faecal-oral route. Diarrhoeal diseases rank as the second leading cause of death among young children in many African nations, resulting in over 3 million fatalities annually. There are different epidemiological patterns observed for various pathogens. The WHO and UNICEF recommend the Integrated Management of Childhood Illnesses (IMCI) strategy at the district level to reduce the morbidity and mortality from childhood diarrhoea."}, {"prompt": "What is the surveillance objective for Diarrhoea with dehydration in children under 5 years? related to Yellow Fever Disease", "completion": "The primary goals are to detect diarrhoea outbreaks quickly. While lab confirmation can pinpoint a specific pathogenic agent causing an outbreak, it isn't necessary for the routine surveillance of diarrhoea with dehydration. Additionally, monitoring antimicrobial resistance is vital during outbreaks of bacterial origin."}, {"prompt": "What is the surveillance target for Diarrhoea with dehydration in children under 5 years? related to Yellow Fever Disease", "completion": "The primary goals are to detect diarrhoea outbreaks quickly. While lab confirmation can pinpoint a specific pathogenic agent causing an outbreak, it isn't necessary for the routine surveillance of diarrhoea with dehydration. Additionally, monitoring antimicrobial resistance is vital during outbreaks of bacterial origin."}, {"prompt": "What are the surveillance objectives for Diarrhoea with dehydration in children under 5 years? related to Yellow Fever Disease", "completion": "The primary goals are to detect diarrhoea outbreaks quickly. While lab confirmation can pinpoint a specific pathogenic agent causing an outbreak, it isn't necessary for the routine surveillance of diarrhoea with dehydration. Additionally, monitoring antimicrobial resistance is vital during outbreaks of bacterial origin."}, {"prompt": "What is the standard case definition for a suspected case of Diarrhoea with dehydration in children under 5 years? related to Yellow Fever Disease", "completion": "A suspected case involves the passage of 3 or more loose or watery stools in the past 24 hours, with or without dehydration. If 'some dehydration' is present, two or more of these signs are evident: restlessness, irritability; sunken eyes; thirst; slow skin pinch retraction. In 'severe dehydration', at least two of these symptoms are present: lethargy or unconsciousness; sunken eyes; difficulty in drinking or drinking poorly; very slow skin pinch retraction."}, {"prompt": "What is the case definition for suspecting a new case of Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "A suspected case involves the passage of 3 or more loose or watery stools in the past 24 hours, with or without dehydration. If 'some dehydration' is present, two or more of these signs are evident: restlessness, irritability; sunken eyes; thirst; slow skin pinch retraction. In 'severe dehydration', at least two of these symptoms are present: lethargy or unconsciousness; sunken eyes; difficulty in drinking or drinking poorly; very slow skin pinch retraction."}, {"prompt": "What is the standard case definition for a confirmed case of Diarrhoea with dehydration in children under 5 years? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case wherein the stool culture tests positive for a known enteric pathogen. However, routinely confirming the specific agent causing an outbreak via laboratory tests isn't recommended for surveillance."}, {"prompt": "How is a confirmed case of Diarrhoea with dehydration in children under 5 years defined? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case wherein the stool culture tests positive for a known enteric pathogen. However, routinely confirming the specific agent causing an outbreak via laboratory tests isn't recommended for surveillance."}, {"prompt": "What is the case definition for confirming a case of Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case wherein the stool culture tests positive for a known enteric pathogen. However, routinely confirming the specific agent causing an outbreak via laboratory tests isn't recommended for surveillance."}, {"prompt": "What are the recommended public health actions in response to an alert threshold for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "In cases where there's an observable increase in the number of cases or deaths over time: Report the anomaly to the next level, investigate the reason for the surge, ensure cases are managed according to IMCI guidelines, and advocate for home-based therapy using oral rehydration."}, {"prompt": "What should be done in response to an alert threshold for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "In cases where there's an observable increase in the number of cases or deaths over time: Report the anomaly to the next level, investigate the reason for the surge, ensure cases are managed according to IMCI guidelines, and advocate for home-based therapy using oral rehydration."}, {"prompt": "How can we respond to an alert threshold for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "In cases where there's an observable increase in the number of cases or deaths over time: Report the anomaly to the next level, investigate the reason for the surge, ensure cases are managed according to IMCI guidelines, and advocate for home-based therapy using oral rehydration."}, {"prompt": "What are the recommended public health actions in response to an action threshold for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "If the number of cases or deaths surges to double the usual number seen in a similar timeframe in the past: Evaluate health worker's adherence to IMCI guidelines for case management, and improve their performance in classifying diarrhoea with dehydration in children under 5. Educate mothers about home-based oral rehydration treatment. Launch community education campaigns about boiling and chlorinating water for safe consumption."}, {"prompt": "What should be done in response to an action threshold for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "If the number of cases or deaths surges to double the usual number seen in a similar timeframe in the past: Evaluate health worker's adherence to IMCI guidelines for case management, and improve their performance in classifying diarrhoea with dehydration in children under 5. Educate mothers about home-based oral rehydration treatment. Launch community education campaigns about boiling and chlorinating water for safe consumption."}, {"prompt": "How can we respond to an action threshold for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "If the number of cases or deaths surges to double the usual number seen in a similar timeframe in the past: Evaluate health worker's adherence to IMCI guidelines for case management, and improve their performance in classifying diarrhoea with dehydration in children under 5. Educate mothers about home-based oral rehydration treatment. Launch community education campaigns about boiling and chlorinating water for safe consumption."}, {"prompt": "How to analyze and interpret data about a person with Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "Monthly report totals for cases due to diarrhoea with some dehydration and for diarrhoea with severe dehydration from outpatient services. Also, report the monthly inpatient total cases and deaths due to diarrhoea with severe dehydration."}, {"prompt": "How to analyze and interpret data about a patient with Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "Monthly report totals for cases due to diarrhoea with some dehydration and for diarrhoea with severe dehydration from outpatient services. Also, report the monthly inpatient total cases and deaths due to diarrhoea with severe dehydration."}, {"prompt": "What methods can be used to analyze and interpret data about individuals with Diarrhoea? related to Yellow Fever Disease", "completion": "Monthly report totals for cases due to diarrhoea with some dehydration and for diarrhoea with severe dehydration from outpatient services. Also, report the monthly inpatient total cases and deaths due to diarrhoea with severe dehydration."}, {"prompt": "How to analyze and interpret data about time in the context of Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed monthly to compare with the same period in previous years. During an outbreak, it's essential to construct an epidemic curve."}, {"prompt": "What methods can be used for temporal analysis of Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed monthly to compare with the same period in previous years. During an outbreak, it's essential to construct an epidemic curve."}, {"prompt": "How can temporal analysis contribute to understanding Diarrhoea trends in children under 5? related to Yellow Fever Disease", "completion": "Cases and deaths should be graphed monthly to compare with the same period in previous years. During an outbreak, it's essential to construct an epidemic curve."}, {"prompt": "How to analyze and interpret data about place in the context of Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "It's crucial to plot the location of case households to understand the geographical spread."}, {"prompt": "What methods can be used for spatial analysis of Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "It's crucial to plot the location of case households to understand the geographical spread."}, {"prompt": "How can spatial analysis contribute to understanding the geographical distribution of Diarrhoea in children under 5? related to Yellow Fever Disease", "completion": "It's crucial to plot the location of case households to understand the geographical spread."}, {"prompt": "What are the laboratory confirmation details for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "Stool cultures may be employed to verify potential outbreaks of specific agents. However, laboratory confirmation is not essential for the case definition."}, {"prompt": "What are the diagnostic criteria for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "Stool cultures may be employed to verify potential outbreaks of specific agents. However, laboratory confirmation is not essential for the case definition."}, {"prompt": "How is Diarrhoea with dehydration in children under 5 diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Stool cultures may be employed to verify potential outbreaks of specific agents. However, laboratory confirmation is not essential for the case definition."}, {"prompt": "What are the references for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "1. Management of childhood illness: Clinical skills training course for first level health facilities. World Health Organization. WHO/CDR/95.14\n2. Integrated Management of Childhood Illness: A WHO/UNICEF Initiative Bulletin of the World Health Organization. Vol. 75, 1997, Supplement 1, 1997. ISBN 92 4 068750 5"}, {"prompt": "What are the recommended sources for information on Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "1. Management of childhood illness: Clinical skills training course for first level health facilities. World Health Organization. WHO/CDR/95.14\n2. Integrated Management of Childhood Illness: A WHO/UNICEF Initiative Bulletin of the World Health Organization. Vol. 75, 1997, Supplement 1, 1997. ISBN 92 4 068750 5"}, {"prompt": "What are the key references for Diarrhoea with dehydration in children under 5? related to Yellow Fever Disease", "completion": "1. Management of childhood illness: Clinical skills training course for first level health facilities. World Health Organization. WHO/CDR/95.14\n2. Integrated Management of Childhood Illness: A WHO/UNICEF Initiative Bulletin of the World Health Organization. Vol. 75, 1997, Supplement 1, 1997. ISBN 92 4 068750 5"}, {"prompt": "Explain Diarrhoea with blood (Shigella). related to Yellow Fever Disease", "completion": "Shigella dysenteriae type 1 (SD1) is the most prevalent cause of enteric infections, transmitted through person-to-person via the faecal-oral route. Large outbreaks may occur with up to 30% of populations affected, potentially leading to a case fatality rate nearing 20% for vulnerable groups like young children and the elderly. Clinical symptoms include fever, bloody diarrhoea, systemic symptoms, and dehydration. The risk factor is largely linked to overcrowded areas with poor sanitation. The bacteria often show resistance to multiple antibiotics. Enterohaemorrhagic and enteroinvasive E. coli, as well as other pathogens like Entamoeba histolytica, may also result in bloody diarrhoea."}, {"prompt": "Describe the characteristics of Diarrhoea with blood (Shigella). related to Yellow Fever Disease", "completion": "Shigella dysenteriae type 1 (SD1) is the most prevalent cause of enteric infections, transmitted through person-to-person via the faecal-oral route. Large outbreaks may occur with up to 30% of populations affected, potentially leading to a case fatality rate nearing 20% for vulnerable groups like young children and the elderly. Clinical symptoms include fever, bloody diarrhoea, systemic symptoms, and dehydration. The risk factor is largely linked to overcrowded areas with poor sanitation. The bacteria often show resistance to multiple antibiotics. Enterohaemorrhagic and enteroinvasive E. coli, as well as other pathogens like Entamoeba histolytica, may also result in bloody diarrhoea."}, {"prompt": "Elaborate on Diarrhoea with blood (Shigella). related to Yellow Fever Disease", "completion": "Shigella dysenteriae type 1 (SD1) is the most prevalent cause of enteric infections, transmitted through person-to-person via the faecal-oral route. Large outbreaks may occur with up to 30% of populations affected, potentially leading to a case fatality rate nearing 20% for vulnerable groups like young children and the elderly. Clinical symptoms include fever, bloody diarrhoea, systemic symptoms, and dehydration. The risk factor is largely linked to overcrowded areas with poor sanitation. The bacteria often show resistance to multiple antibiotics. Enterohaemorrhagic and enteroinvasive E. coli, as well as other pathogens like Entamoeba histolytica, may also result in bloody diarrhoea."}, {"prompt": "Define Diarrhoea with blood (Shigella). related to Yellow Fever Disease", "completion": "Shigella dysenteriae type 1 (SD1) is the most prevalent cause of enteric infections, transmitted through person-to-person via the faecal-oral route. Large outbreaks may occur with up to 30% of populations affected, potentially leading to a case fatality rate nearing 20% for vulnerable groups like young children and the elderly. Clinical symptoms include fever, bloody diarrhoea, systemic symptoms, and dehydration. The risk factor is largely linked to overcrowded areas with poor sanitation. The bacteria often show resistance to multiple antibiotics. Enterohaemorrhagic and enteroinvasive E. coli, as well as other pathogens like Entamoeba histolytica, may also result in bloody diarrhoea."}, {"prompt": "What is the nature of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Shigella dysenteriae type 1 (SD1) is the most prevalent cause of enteric infections, transmitted through person-to-person via the faecal-oral route. Large outbreaks may occur with up to 30% of populations affected, potentially leading to a case fatality rate nearing 20% for vulnerable groups like young children and the elderly. Clinical symptoms include fever, bloody diarrhoea, systemic symptoms, and dehydration. The risk factor is largely linked to overcrowded areas with poor sanitation. The bacteria often show resistance to multiple antibiotics. Enterohaemorrhagic and enteroinvasive E. coli, as well as other pathogens like Entamoeba histolytica, may also result in bloody diarrhoea."}, {"prompt": "What is the surveillance objective for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "The objectives are to promptly detect and address dysentery outbreaks, enhance the percentage of lab-confirmed cases and ascertain the proportion that are type 1 (SD1). Furthermore, it is essential to determine the antibiotic sensitivity pattern of isolated agents, especially during outbreaks."}, {"prompt": "What is the purpose of surveillance for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "The objectives are to promptly detect and address dysentery outbreaks, enhance the percentage of lab-confirmed cases and ascertain the proportion that are type 1 (SD1). Furthermore, it is essential to determine the antibiotic sensitivity pattern of isolated agents, especially during outbreaks."}, {"prompt": "What is the goal of surveillance for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "The objectives are to promptly detect and address dysentery outbreaks, enhance the percentage of lab-confirmed cases and ascertain the proportion that are type 1 (SD1). Furthermore, it is essential to determine the antibiotic sensitivity pattern of isolated agents, especially during outbreaks."}, {"prompt": "What is the standard case definition for a suspected case of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "A suspected case is defined as a person presenting with diarrhoea accompanied by visible blood in the stool."}, {"prompt": "When should a person be suspected to have Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "A suspected case is defined as a person presenting with diarrhoea accompanied by visible blood in the stool."}, {"prompt": "What is the case definition for suspecting a new case of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "A suspected case is defined as a person presenting with diarrhoea accompanied by visible blood in the stool."}, {"prompt": "What is the standard case definition for a confirmed case of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case where the stool culture tests positive for Shigella dysenteriae type 1."}, {"prompt": "How is a confirmed case of Diarrhoea with blood (Shigella) defined? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case where the stool culture tests positive for Shigella dysenteriae type 1."}, {"prompt": "What criteria are used to confirm a case of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case where the stool culture tests positive for Shigella dysenteriae type 1."}, {"prompt": "When should an alert threshold be raised for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Upon noticing an increase in the number of cases or deaths over time: Report the surge to the next health system level, treat suspected cases with oral rehydration and antibiotics based on recent susceptibility results, collect stool or rectal swab specimen for confirming the SD1 outbreak, and investigate the case to ascertain risk factors contributing to transmission."}, {"prompt": "What actions should be taken in response to an alert threshold for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Upon noticing an increase in the number of cases or deaths over time: Report the surge to the next health system level, treat suspected cases with oral rehydration and antibiotics based on recent susceptibility results, collect stool or rectal swab specimen for confirming the SD1 outbreak, and investigate the case to ascertain risk factors contributing to transmission."}, {"prompt": "How to respond to an alert threshold for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Upon noticing an increase in the number of cases or deaths over time: Report the surge to the next health system level, treat suspected cases with oral rehydration and antibiotics based on recent susceptibility results, collect stool or rectal swab specimen for confirming the SD1 outbreak, and investigate the case to ascertain risk factors contributing to transmission."}, {"prompt": "What are the recommended public health actions in response to an action threshold for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "If an outbreak is confirmed, actions include: searching for additional cases in the locality of the confirmed cases, enhancing case management and treatment, mobilizing the community for rapid case detection and treatment, identifying high-risk populations using data on person, place, and time, promoting hand-washing, ensuring access to safe water, and facilitating the use of latrines and safe waste disposal."}, {"prompt": "What steps should be taken in response to an action threshold for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "If an outbreak is confirmed, actions include: searching for additional cases in the locality of the confirmed cases, enhancing case management and treatment, mobilizing the community for rapid case detection and treatment, identifying high-risk populations using data on person, place, and time, promoting hand-washing, ensuring access to safe water, and facilitating the use of latrines and safe waste disposal."}, {"prompt": "How to respond to an action threshold for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "If an outbreak is confirmed, actions include: searching for additional cases in the locality of the confirmed cases, enhancing case management and treatment, mobilizing the community for rapid case detection and treatment, identifying high-risk populations using data on person, place, and time, promoting hand-washing, ensuring access to safe water, and facilitating the use of latrines and safe waste disposal."}, {"prompt": "How to analyze and interpret data about individuals with Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Count cases and deaths each month. During an outbreak, count outbreak-related cases weekly. Regularly analyze the age distribution and assess risk factors to enhance control and prevention measures."}, {"prompt": "What are the methods of data analysis for individuals with Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Count cases and deaths each month. During an outbreak, count outbreak-related cases weekly. Regularly analyze the age distribution and assess risk factors to enhance control and prevention measures."}, {"prompt": "How can we interpret the data on individuals with Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Count cases and deaths each month. During an outbreak, count outbreak-related cases weekly. Regularly analyze the age distribution and assess risk factors to enhance control and prevention measures."}, {"prompt": "How to analyze and interpret data about time in the context of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Monthly trends in cases and deaths should be graphed. During an outbreak, it's crucial to construct an epidemic curve."}, {"prompt": "What are the techniques used for temporal analysis of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Monthly trends in cases and deaths should be graphed. During an outbreak, it's crucial to construct an epidemic curve."}, {"prompt": "How can temporal analysis help in understanding Diarrhoea with blood (Shigella) trends? related to Yellow Fever Disease", "completion": "Monthly trends in cases and deaths should be graphed. During an outbreak, it's crucial to construct an epidemic curve."}, {"prompt": "How to analyze and interpret data about place in the context of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "It's vital to plot the location of case households."}, {"prompt": "What are the methods used for spatial analysis of Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "It's vital to plot the location of case households."}, {"prompt": "How can spatial analysis contribute to understanding Diarrhoea with blood (Shigella) transmission? related to Yellow Fever Disease", "completion": "It's vital to plot the location of case households."}, {"prompt": "What are the laboratory procedures for diagnosing Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "Diagnostic tests include isolating Shigella dysenteriae type 1 (SD1) in culture to confirm a shigella outbreak and, if SD1 is confirmed, conducting antibiotic sensitivity tests. The specimen used is stool or a rectal swab. For each new area affected by the outbreak, laboratory confirmation should be obtained. Specimens should be collected when an outbreak is suspected, ideally from 5-10 patients displaying symptoms. Specimens should be placed in Cary-Blair transport medium and sent to the laboratory refrigerated. Culture results typically become available 2 to 4 days after the laboratory receives them. Following the confirmation of the initial 5-10 cases in an outbreak, only a few cases should be sampled to monitor the outbreak's cessation and any changes in antibiotic sensitivity patterns."}, {"prompt": "How is Diarrhoea with blood (Shigella) diagnosed in the laboratory? related to Yellow Fever Disease", "completion": "Diagnostic tests include isolating Shigella dysenteriae type 1 (SD1) in culture to confirm a shigella outbreak and, if SD1 is confirmed, conducting antibiotic sensitivity tests. The specimen used is stool or a rectal swab. For each new area affected by the outbreak, laboratory confirmation should be obtained. Specimens should be collected when an outbreak is suspected, ideally from 5-10 patients displaying symptoms. Specimens should be placed in Cary-Blair transport medium and sent to the laboratory refrigerated. Culture results typically become available 2 to 4 days after the laboratory receives them. Following the confirmation of the initial 5-10 cases in an outbreak, only a few cases should be sampled to monitor the outbreak's cessation and any changes in antibiotic sensitivity patterns."}, {"prompt": "What are the references for Diarrhoea with blood (Shigella)? related to Yellow Fever Disease", "completion": "1. Guidelines for the control of epidemics due to Shigella dysenteriae type 1. WHO/CDR/95.4\n2. Safe Water Systems for the Developing World: A Handbook for Implementing Household-based Water Treatment and Safe Storage Projects. Department of Health & Human Services. Centers for Disease Control and Prevention. Atlanta. 2000\n3. Laboratory Methods for the Diagnosis of Epidemic Dysentery and Cholera."}, {"prompt": "Explain Diabetes. related to Yellow Fever Disease", "completion": "Diabetes mellitus (DM) is a chronic disease arising when the pancreas does not produce enough insulin or when the body cannot use the insulin it produces effectively. This leads to serious health issues like heart disease, blindness, kidney failure, and amputations. The most common form is Type 2 diabetes. Risk factors include age, family history, obesity, physical inactivity, and excessive alcohol consumption. Global prevalence in 2000 was around 2.8%, expected to rise to 4.8% by 2030. Diabetes is increasingly common in Africa, with recent estimates showing a prevalence between 1% and 20%. Diabetes can lead to limb amputations and has a high mortality rate in some African countries. Efforts in the African Region to combat diabetes include resolutions on non-communicable diseases, cardiovascular diseases strategy, and diabetes mellitus strategy. The World Health Organization and the International Diabetes Federation have also promoted diabetes awareness in Africa."}, {"prompt": "Define Diabetes. related to Yellow Fever Disease", "completion": "Diabetes mellitus (DM) is a chronic disease arising when the pancreas does not produce enough insulin or when the body cannot use the insulin it produces effectively. This leads to serious health issues like heart disease, blindness, kidney failure, and amputations. The most common form is Type 2 diabetes. Risk factors include age, family history, obesity, physical inactivity, and excessive alcohol consumption. Global prevalence in 2000 was around 2.8%, expected to rise to 4.8% by 2030. Diabetes is increasingly common in Africa, with recent estimates showing a prevalence between 1% and 20%. Diabetes can lead to limb amputations and has a high mortality rate in some African countries. Efforts in the African Region to combat diabetes include resolutions on non-communicable diseases, cardiovascular diseases strategy, and diabetes mellitus strategy. The World Health Organization and the International Diabetes Federation have also promoted diabetes awareness in Africa."}, {"prompt": "Describe Diabetes. related to Yellow Fever Disease", "completion": "Diabetes mellitus (DM) is a chronic disease arising when the pancreas does not produce enough insulin or when the body cannot use the insulin it produces effectively. This leads to serious health issues like heart disease, blindness, kidney failure, and amputations. The most common form is Type 2 diabetes. Risk factors include age, family history, obesity, physical inactivity, and excessive alcohol consumption. Global prevalence in 2000 was around 2.8%, expected to rise to 4.8% by 2030. Diabetes is increasingly common in Africa, with recent estimates showing a prevalence between 1% and 20%. Diabetes can lead to limb amputations and has a high mortality rate in some African countries. Efforts in the African Region to combat diabetes include resolutions on non-communicable diseases, cardiovascular diseases strategy, and diabetes mellitus strategy. The World Health Organization and the International Diabetes Federation have also promoted diabetes awareness in Africa."}, {"prompt": "What is Diabetes Mellitus? related to Yellow Fever Disease", "completion": "Diabetes mellitus (DM) is a chronic disease arising when the pancreas does not produce enough insulin or when the body cannot use the insulin it produces effectively. This leads to serious health issues like heart disease, blindness, kidney failure, and amputations. The most common form is Type 2 diabetes. Risk factors include age, family history, obesity, physical inactivity, and excessive alcohol consumption. Global prevalence in 2000 was around 2.8%, expected to rise to 4.8% by 2030. Diabetes is increasingly common in Africa, with recent estimates showing a prevalence between 1% and 20%. Diabetes can lead to limb amputations and has a high mortality rate in some African countries. Efforts in the African Region to combat diabetes include resolutions on non-communicable diseases, cardiovascular diseases strategy, and diabetes mellitus strategy. The World Health Organization and the International Diabetes Federation have also promoted diabetes awareness in Africa."}, {"prompt": "What is the goal of diabetes surveillance? related to Yellow Fever Disease", "completion": "The goals are to estimate the disease's magnitude, monitor its trends and risk factors, identify high-risk populations (like specific age groups or urban vs. rural residents), and oversee prevention and control program activities."}, {"prompt": "What are the objectives of diabetes surveillance? related to Yellow Fever Disease", "completion": "The goals are to estimate the disease's magnitude, monitor its trends and risk factors, identify high-risk populations (like specific age groups or urban vs. rural residents), and oversee prevention and control program activities."}, {"prompt": "What is the surveillance objective for Diabetes? related to Yellow Fever Disease", "completion": "The goals are to estimate the disease's magnitude, monitor its trends and risk factors, identify high-risk populations (like specific age groups or urban vs. rural residents), and oversee prevention and control program activities."}, {"prompt": "What is the standard case definition for a suspected new case of Diabetes? related to Yellow Fever Disease", "completion": "A suspected new case is any person presenting with increased thirst, increased hunger, and frequent urination."}, {"prompt": "When should a person be suspected to have Diabetes? related to Yellow Fever Disease", "completion": "A suspected new case is any person presenting with increased thirst, increased hunger, and frequent urination."}, {"prompt": "What criteria are used to suspect a new case of Diabetes? related to Yellow Fever Disease", "completion": "A suspected new case is any person presenting with increased thirst, increased hunger, and frequent urination."}, {"prompt": "What is the standard case definition for a confirmed case of Diabetes? related to Yellow Fever Disease", "completion": "A confirmed case is any person with a fasting venous plasma glucose measurement of \u2265 7 mmol/L (126 mg/dl) or capillary glucose \u2265 6.1 mmol/L (110 mg/dl) or a non-fasting venous plasma glucose measurement of \u2265 11.1mmol/L (200 mg/dl) or capillary glucose \u2265 11,1 mmol/L (200 mg/dl). Only the first lab-confirmed diagnosis of the patient is reported."}, {"prompt": "How is a confirmed case of Diabetes defined? related to Yellow Fever Disease", "completion": "A confirmed case is any person with a fasting venous plasma glucose measurement of \u2265 7 mmol/L (126 mg/dl) or capillary glucose \u2265 6.1 mmol/L (110 mg/dl) or a non-fasting venous plasma glucose measurement of \u2265 11.1mmol/L (200 mg/dl) or capillary glucose \u2265 11,1 mmol/L (200 mg/dl). Only the first lab-confirmed diagnosis of the patient is reported."}, {"prompt": "What are the diagnostic criteria for a confirmed case of Diabetes? related to Yellow Fever Disease", "completion": "A confirmed case is any person with a fasting venous plasma glucose measurement of \u2265 7 mmol/L (126 mg/dl) or capillary glucose \u2265 6.1 mmol/L (110 mg/dl) or a non-fasting venous plasma glucose measurement of \u2265 11.1mmol/L (200 mg/dl) or capillary glucose \u2265 11,1 mmol/L (200 mg/dl). Only the first lab-confirmed diagnosis of the patient is reported."}, {"prompt": "What are the recommended public health actions for people with diabetes? related to Yellow Fever Disease", "completion": "Those with diabetes should be treated according to the standardized case management guidelines (WHOPEN)."}, {"prompt": "How should individuals with diabetes be managed according to public health guidelines? related to Yellow Fever Disease", "completion": "Those with diabetes should be treated according to the standardized case management guidelines (WHOPEN)."}, {"prompt": "What public health measures are recommended for people with diabetes? related to Yellow Fever Disease", "completion": "Those with diabetes should be treated according to the standardized case management guidelines (WHOPEN)."}, {"prompt": "What are the district-level preventive measures for Diabetes? related to Yellow Fever Disease", "completion": "Implement an integrated prevention and control program for non-communicable diseases, focusing on diabetes. This involves community awareness and education activities in line with national prevention and control programs, including strategies for diet, weight-reduction, and physical activity. Clinical preventive measures and treatment interventions should be implemented using evidence-based guidelines."}, {"prompt": "How can districts prevent and control Diabetes? related to Yellow Fever Disease", "completion": "Implement an integrated prevention and control program for non-communicable diseases, focusing on diabetes. This involves community awareness and education activities in line with national prevention and control programs, including strategies for diet, weight-reduction, and physical activity. Clinical preventive measures and treatment interventions should be implemented using evidence-based guidelines."}, {"prompt": "What actions should be taken at the district level to prevent and control Diabetes? related to Yellow Fever Disease", "completion": "Implement an integrated prevention and control program for non-communicable diseases, focusing on diabetes. This involves community awareness and education activities in line with national prevention and control programs, including strategies for diet, weight-reduction, and physical activity. Clinical preventive measures and treatment interventions should be implemented using evidence-based guidelines."}, {"prompt": "How to analyze and interpret data about a person with Diabetes? related to Yellow Fever Disease", "completion": "It's crucial to analyze the distribution of cases by age and other demographic factors."}, {"prompt": "What data analysis methods are used to understand Diabetes cases? related to Yellow Fever Disease", "completion": "It's crucial to analyze the distribution of cases by age and other demographic factors."}, {"prompt": "How can we interpret data about individuals with Diabetes? related to Yellow Fever Disease", "completion": "It's crucial to analyze the distribution of cases by age and other demographic factors."}, {"prompt": "How to analyze and interpret data about time in the context of Diabetes? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly to understand trends. Data for non-communicable diseases like diabetes should be analyzed for long-term trends."}, {"prompt": "What are the techniques for analyzing temporal trends in Diabetes cases? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly to understand trends. Data for non-communicable diseases like diabetes should be analyzed for long-term trends."}, {"prompt": "How can temporal analysis help in understanding Diabetes trends? related to Yellow Fever Disease", "completion": "Cases should be graphed quarterly to understand trends. Data for non-communicable diseases like diabetes should be analyzed for long-term trends."}, {"prompt": "How to analyze and interpret data about place in the context of Diabetes? related to Yellow Fever Disease", "completion": "It's important to compare district trends with national and regional trends."}, {"prompt": "What methods are used for spatial analysis of Diabetes cases? related to Yellow Fever Disease", "completion": "It's important to compare district trends with national and regional trends."}, {"prompt": "How can spatial analysis contribute to understanding Diabetes transmission? related to Yellow Fever Disease", "completion": "It's important to compare district trends with national and regional trends."}, {"prompt": "Where can I find references for Diabetes? related to Yellow Fever Disease", "completion": "1. Non-communicable Diseases: A strategy for the African Region, AFR/RC50/10\n2. Cardiovascular Diseases in the African Region: Current situation and perspectives, AFR/RC55/12,429\n3. Diabetes prevention and control: a strategy for the African Region, AFR/RC57/7\n4. Steps manual: http://www.who.int/chp/steps/en/\n5. Gojka R et al, Global prevalence of diabetes, Diabetes care 27(5): 1047-1053, 2004.\n6. IDF, Diabetes Atlas, 2nd Edition, Brussels, International Diabetes Federation, 2003.\n7. WHO, Preventing chronic diseases: A vital investment, Geneva, World Health Organization, 2005\n8. WHO, The burden of mortality attributable to diabetes, Geneva, World Health Organization, 2004.\n9. WHO-PEN: Protocols for health promotion, prevention and management of NCDs at primary care level http://www.afro.who.int/en/divisions-a- programmes/ddc/division/2257- who-pen-protocols.html\n10. District Laboratory Practice in Tropical countries, Cambridge"}, {"prompt": "What sources can I consult for Diabetes information? related to Yellow Fever Disease", "completion": "1. Non-communicable Diseases: A strategy for the African Region, AFR/RC50/10\n2. Cardiovascular Diseases in the African Region: Current situation and perspectives, AFR/RC55/12,429\n3. Diabetes prevention and control: a strategy for the African Region, AFR/RC57/7\n4. Steps manual: http://www.who.int/chp/steps/en/\n5. Gojka R et al, Global prevalence of diabetes, Diabetes care 27(5): 1047-1053, 2004.\n6. IDF, Diabetes Atlas, 2nd Edition, Brussels, International Diabetes Federation, 2003.\n7. WHO, Preventing chronic diseases: A vital investment, Geneva, World Health Organization, 2005\n8. WHO, The burden of mortality attributable to diabetes, Geneva, World Health Organization, 2004.\n9. WHO-PEN: Protocols for health promotion, prevention and management of NCDs at primary care level http://www.afro.who.int/en/divisions-a- programmes/ddc/division/2257- who-pen-protocols.html\n10. District Laboratory Practice in Tropical countries, Cambridge"}, {"prompt": "Explain Dengue Fever. related to Yellow Fever Disease", "completion": "Dengue fever is an arbovirus transmitted by Aedes mosquitoes, including both Ae. aegypti and Ae. albopiticus. It is caused by four closely related viruses: dengue virus (DENV) 1, 2, 3, and 4. Dengue is prevalent in tropical and sub-tropical regions, primarily in urban and semi-urban areas. The disease can present as a severe, influenza-like illness in infants, young children, and adults. Dengue haemorrhagic fever (DHF) is a potentially fatal complication, especially common in Asia. Sequential infection with different dengue virus serotypes can increase the risk of severe disease. Epidemic dengue activity in Africa has been mostly mild, but a significant outbreak of DENV-3 occurred in Mozambique in 1984-1985. The main carriers of the virus are infected humans, and the primary transmission mode is through Aedes aegypti mosquitoes. There's no specific treatment for dengue, but appropriate medical care can be life-saving. The only prevention method currently available is controlling the vector mosquitoes."}, {"prompt": "Describe Dengue Fever. related to Yellow Fever Disease", "completion": "Dengue fever is an arbovirus transmitted by Aedes mosquitoes, including both Ae. aegypti and Ae. albopiticus. It is caused by four closely related viruses: dengue virus (DENV) 1, 2, 3, and 4. Dengue is prevalent in tropical and sub-tropical regions, primarily in urban and semi-urban areas. The disease can present as a severe, influenza-like illness in infants, young children, and adults. Dengue haemorrhagic fever (DHF) is a potentially fatal complication, especially common in Asia. Sequential infection with different dengue virus serotypes can increase the risk of severe disease. Epidemic dengue activity in Africa has been mostly mild, but a significant outbreak of DENV-3 occurred in Mozambique in 1984-1985. The main carriers of the virus are infected humans, and the primary transmission mode is through Aedes aegypti mosquitoes. There's no specific treatment for dengue, but appropriate medical care can be life-saving. The only prevention method currently available is controlling the vector mosquitoes."}, {"prompt": "Elaborate on Dengue Fever. related to Yellow Fever Disease", "completion": "Dengue fever is an arbovirus transmitted by Aedes mosquitoes, including both Ae. aegypti and Ae. albopiticus. It is caused by four closely related viruses: dengue virus (DENV) 1, 2, 3, and 4. Dengue is prevalent in tropical and sub-tropical regions, primarily in urban and semi-urban areas. The disease can present as a severe, influenza-like illness in infants, young children, and adults. Dengue haemorrhagic fever (DHF) is a potentially fatal complication, especially common in Asia. Sequential infection with different dengue virus serotypes can increase the risk of severe disease. Epidemic dengue activity in Africa has been mostly mild, but a significant outbreak of DENV-3 occurred in Mozambique in 1984-1985. The main carriers of the virus are infected humans, and the primary transmission mode is through Aedes aegypti mosquitoes. There's no specific treatment for dengue, but appropriate medical care can be life-saving. The only prevention method currently available is controlling the vector mosquitoes."}, {"prompt": "Define Dengue Fever. related to Yellow Fever Disease", "completion": "Dengue fever is an arbovirus transmitted by Aedes mosquitoes, including both Ae. aegypti and Ae. albopiticus. It is caused by four closely related viruses: dengue virus (DENV) 1, 2, 3, and 4. Dengue is prevalent in tropical and sub-tropical regions, primarily in urban and semi-urban areas. The disease can present as a severe, influenza-like illness in infants, young children, and adults. Dengue haemorrhagic fever (DHF) is a potentially fatal complication, especially common in Asia. Sequential infection with different dengue virus serotypes can increase the risk of severe disease. Epidemic dengue activity in Africa has been mostly mild, but a significant outbreak of DENV-3 occurred in Mozambique in 1984-1985. The main carriers of the virus are infected humans, and the primary transmission mode is through Aedes aegypti mosquitoes. There's no specific treatment for dengue, but appropriate medical care can be life-saving. The only prevention method currently available is controlling the vector mosquitoes."}, {"prompt": "What is the nature of Dengue Fever? related to Yellow Fever Disease", "completion": "Dengue fever is an arbovirus transmitted by Aedes mosquitoes, including both Ae. aegypti and Ae. albopiticus. It is caused by four closely related viruses: dengue virus (DENV) 1, 2, 3, and 4. Dengue is prevalent in tropical and sub-tropical regions, primarily in urban and semi-urban areas. The disease can present as a severe, influenza-like illness in infants, young children, and adults. Dengue haemorrhagic fever (DHF) is a potentially fatal complication, especially common in Asia. Sequential infection with different dengue virus serotypes can increase the risk of severe disease. Epidemic dengue activity in Africa has been mostly mild, but a significant outbreak of DENV-3 occurred in Mozambique in 1984-1985. The main carriers of the virus are infected humans, and the primary transmission mode is through Aedes aegypti mosquitoes. There's no specific treatment for dengue, but appropriate medical care can be life-saving. The only prevention method currently available is controlling the vector mosquitoes."}, {"prompt": "What is the objective of Dengue Fever surveillance? related to Yellow Fever Disease", "completion": "The surveillance goal is to monitor suspected cases and investigate clusters of suspected cases in areas with Ae. aegypti and Ae. albopiticus mosquitoes."}, {"prompt": "What is the aim of Dengue Fever surveillance? related to Yellow Fever Disease", "completion": "The surveillance goal is to monitor suspected cases and investigate clusters of suspected cases in areas with Ae. aegypti and Ae. albopiticus mosquitoes."}, {"prompt": "What is the target of Dengue Fever surveillance? related to Yellow Fever Disease", "completion": "The surveillance goal is to monitor suspected cases and investigate clusters of suspected cases in areas with Ae. aegypti and Ae. albopiticus mosquitoes."}, {"prompt": "What is the standard case definition for a suspected case of Dengue Fever? related to Yellow Fever Disease", "completion": "A suspected case is any person with an acute febrile illness lasting 2-7 days and exhibiting 2 or more of the following symptoms: headache, retro-orbital pain, myalgia, arthralgia, rash, haemorrhagic manifestations, or leucopenia."}, {"prompt": "What are the criteria for a suspected case of Dengue Fever? related to Yellow Fever Disease", "completion": "A suspected case is any person with an acute febrile illness lasting 2-7 days and exhibiting 2 or more of the following symptoms: headache, retro-orbital pain, myalgia, arthralgia, rash, haemorrhagic manifestations, or leucopenia."}, {"prompt": "How is a confirmed case of Dengue Fever defined? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case with laboratory confirmation, which could be through positive IgM antibody, a rise in IgG antibody titres, positive PCR, or viral isolation."}, {"prompt": "What are the criteria for a confirmed case of Dengue Fever? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case with laboratory confirmation, which could be through positive IgM antibody, a rise in IgG antibody titres, positive PCR, or viral isolation."}, {"prompt": "When Dengue Fever cases are suspected, how should one respond to the alert threshold? related to Yellow Fever Disease", "completion": "Immediate reporting of case-based information is vital. Active searches for additional cases should be conducted, and specimens should be collected for confirmation."}, {"prompt": "When Dengue Fever cases are suspected, what actions should be taken in response to the alert threshold? related to Yellow Fever Disease", "completion": "Immediate reporting of case-based information is vital. Active searches for additional cases should be conducted, and specimens should be collected for confirmation."}, {"prompt": "When Dengue Fever cases are confirmed, how should one respond to the action threshold? related to Yellow Fever Disease", "completion": "Upon confirmation, report the case-based information immediately. Conduct an active search for additional cases and collect specimens for further confirmation. Survey the community for the abundance of vector mosquitoes and promote plans for their elimination. Educate the public about behaviors to manage mosquito vector habitats. Provide supportive treatment to dengue fever cases, ensuring standard infection control precautions. Prevent mosquitoes from accessing patients by using mosquito bed nets. Suspected DHF/DSS cases should be referred to more advanced facilities."}, {"prompt": "When Dengue Fever cases are confirmed, what actions should be taken in response to the action threshold? related to Yellow Fever Disease", "completion": "Upon confirmation, report the case-based information immediately. Conduct an active search for additional cases and collect specimens for further confirmation. Survey the community for the abundance of vector mosquitoes and promote plans for their elimination. Educate the public about behaviors to manage mosquito vector habitats. Provide supportive treatment to dengue fever cases, ensuring standard infection control precautions. Prevent mosquitoes from accessing patients by using mosquito bed nets. Suspected DHF/DSS cases should be referred to more advanced facilities."}, {"prompt": "How should data about a person with Dengue Fever be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Calculate the case-fatality rate. Analyze the distribution of cases by age and sex. Determine the percentage of DHF/DSS cases and hospitalizations. Assess the risk factors to enhance control measures."}, {"prompt": "What are the methods to analyze data about a person with Dengue Fever? related to Yellow Fever Disease", "completion": "Calculate the case-fatality rate. Analyze the distribution of cases by age and sex. Determine the percentage of DHF/DSS cases and hospitalizations. Assess the risk factors to enhance control measures."}, {"prompt": "How to analyze and interpret data about time in the context of Dengue Fever? related to Yellow Fever Disease", "completion": "Graph cases and deaths on a weekly/monthly basis. Construct an epidemic curve during outbreaks. Immediate case-based information and monthly summary information are essential for routine surveillance."}, {"prompt": "What are the techniques for temporal analysis of Dengue Fever cases? related to Yellow Fever Disease", "completion": "Graph cases and deaths on a weekly/monthly basis. Construct an epidemic curve during outbreaks. Immediate case-based information and monthly summary information are essential for routine surveillance."}, {"prompt": "How to analyze and interpret data about place in the context of Dengue Fever? related to Yellow Fever Disease", "completion": "Precisely map the location of case households and work sites."}, {"prompt": "What are the methods for spatial analysis of Dengue Fever cases? related to Yellow Fever Disease", "completion": "Precisely map the location of case households and work sites."}, {"prompt": "What is the significance of spatial analysis in understanding Dengue Fever transmission? related to Yellow Fever Disease", "completion": "Precisely map the location of case households and work sites."}, {"prompt": "Where can I find more information about Dengue Fever? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n2. Dengue: Clinical and Public Health Aspects/CDC"}, {"prompt": "What are the resources available for Dengue Fever? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n2. Dengue: Clinical and Public Health Aspects/CDC"}, {"prompt": "How can I access additional information about Dengue Fever? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n2. Dengue: Clinical and Public Health Aspects/CDC"}, {"prompt": "What are the references for Dengue Fever? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n2. Dengue: Clinical and Public Health Aspects/CDC"}, {"prompt": "Where can I find the recommended guidelines for Dengue Fever? related to Yellow Fever Disease", "completion": "1. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n2. Dengue: Clinical and Public Health Aspects/CDC"}, {"prompt": "Explain Cholera. related to Yellow Fever Disease", "completion": "Cholera is an acute illness with profuse watery diarrhoea caused by Vibrio cholerae serogroups O1 or O139. The disease is transmitted mainly through the faecal-oral route, i.e., through consuming contaminated food or water. Cholera results in over 100,000 deaths annually and can produce rapidly advancing epidemics or global pandemics. In endemic regions, sporadic cases and small outbreaks can occur. The incubation period ranges from a few hours to 5 days. Since the mid-1980s, there has been a resurgence of cholera in Africa. Cholera can lead to severe dehydration within a few hours, and without treatment, the fatality rate may exceed 50%. With proper treatment at a healthcare facility, the fatality rate is usually less than 1%. About 90% of the cases are mild and often go undiagnosed. Risk factors include consuming contaminated foods, lack of access to clean water, attending large gatherings, and contact with cholera patients."}, {"prompt": "Describe Cholera. related to Yellow Fever Disease", "completion": "Cholera is an acute illness with profuse watery diarrhoea caused by Vibrio cholerae serogroups O1 or O139. The disease is transmitted mainly through the faecal-oral route, i.e., through consuming contaminated food or water. Cholera results in over 100,000 deaths annually and can produce rapidly advancing epidemics or global pandemics. In endemic regions, sporadic cases and small outbreaks can occur. The incubation period ranges from a few hours to 5 days. Since the mid-1980s, there has been a resurgence of cholera in Africa. Cholera can lead to severe dehydration within a few hours, and without treatment, the fatality rate may exceed 50%. With proper treatment at a healthcare facility, the fatality rate is usually less than 1%. About 90% of the cases are mild and often go undiagnosed. Risk factors include consuming contaminated foods, lack of access to clean water, attending large gatherings, and contact with cholera patients."}, {"prompt": "Elaborate on Cholera. related to Yellow Fever Disease", "completion": "Cholera is an acute illness with profuse watery diarrhoea caused by Vibrio cholerae serogroups O1 or O139. The disease is transmitted mainly through the faecal-oral route, i.e., through consuming contaminated food or water. Cholera results in over 100,000 deaths annually and can produce rapidly advancing epidemics or global pandemics. In endemic regions, sporadic cases and small outbreaks can occur. The incubation period ranges from a few hours to 5 days. Since the mid-1980s, there has been a resurgence of cholera in Africa. Cholera can lead to severe dehydration within a few hours, and without treatment, the fatality rate may exceed 50%. With proper treatment at a healthcare facility, the fatality rate is usually less than 1%. About 90% of the cases are mild and often go undiagnosed. Risk factors include consuming contaminated foods, lack of access to clean water, attending large gatherings, and contact with cholera patients."}, {"prompt": "Define Cholera. related to Yellow Fever Disease", "completion": "Cholera is an acute illness with profuse watery diarrhoea caused by Vibrio cholerae serogroups O1 or O139. The disease is transmitted mainly through the faecal-oral route, i.e., through consuming contaminated food or water. Cholera results in over 100,000 deaths annually and can produce rapidly advancing epidemics or global pandemics. In endemic regions, sporadic cases and small outbreaks can occur. The incubation period ranges from a few hours to 5 days. Since the mid-1980s, there has been a resurgence of cholera in Africa. Cholera can lead to severe dehydration within a few hours, and without treatment, the fatality rate may exceed 50%. With proper treatment at a healthcare facility, the fatality rate is usually less than 1%. About 90% of the cases are mild and often go undiagnosed. Risk factors include consuming contaminated foods, lack of access to clean water, attending large gatherings, and contact with cholera patients."}, {"prompt": "What is the nature of Cholera? related to Yellow Fever Disease", "completion": "Cholera is an acute illness with profuse watery diarrhoea caused by Vibrio cholerae serogroups O1 or O139. The disease is transmitted mainly through the faecal-oral route, i.e., through consuming contaminated food or water. Cholera results in over 100,000 deaths annually and can produce rapidly advancing epidemics or global pandemics. In endemic regions, sporadic cases and small outbreaks can occur. The incubation period ranges from a few hours to 5 days. Since the mid-1980s, there has been a resurgence of cholera in Africa. Cholera can lead to severe dehydration within a few hours, and without treatment, the fatality rate may exceed 50%. With proper treatment at a healthcare facility, the fatality rate is usually less than 1%. About 90% of the cases are mild and often go undiagnosed. Risk factors include consuming contaminated foods, lack of access to clean water, attending large gatherings, and contact with cholera patients."}, {"prompt": "What is the goal of Cholera surveillance? related to Yellow Fever Disease", "completion": "The goal is to detect and respond promptly and appropriately to cases and outbreaks of watery diarrhoea. To confirm an outbreak, stool specimens should be collected and transported in Cary-Blair medium. Immediate case-based reporting of cases and deaths is essential when an outbreak is suspected."}, {"prompt": "What are the objectives of Cholera surveillance? related to Yellow Fever Disease", "completion": "The goal is to detect and respond promptly and appropriately to cases and outbreaks of watery diarrhoea. To confirm an outbreak, stool specimens should be collected and transported in Cary-Blair medium. Immediate case-based reporting of cases and deaths is essential when an outbreak is suspected."}, {"prompt": "What is the aim of Cholera surveillance? related to Yellow Fever Disease", "completion": "The goal is to detect and respond promptly and appropriately to cases and outbreaks of watery diarrhoea. To confirm an outbreak, stool specimens should be collected and transported in Cary-Blair medium. Immediate case-based reporting of cases and deaths is essential when an outbreak is suspected."}, {"prompt": "What is the standard case definition for a suspected case of Cholera? related to Yellow Fever Disease", "completion": "For a patient aged 5 years or older, it is severe dehydration or death from acute watery diarrhoea. If a cholera epidemic is ongoing, a suspected case can be any individual aged 5 years or more presenting with acute watery diarrhoea, with or without vomiting."}, {"prompt": "When should a person be suspected to have Cholera? related to Yellow Fever Disease", "completion": "For a patient aged 5 years or older, it is severe dehydration or death from acute watery diarrhoea. If a cholera epidemic is ongoing, a suspected case can be any individual aged 5 years or more presenting with acute watery diarrhoea, with or without vomiting."}, {"prompt": "What criteria are used to suspect Cholera? related to Yellow Fever Disease", "completion": "For a patient aged 5 years or older, it is severe dehydration or death from acute watery diarrhoea. If a cholera epidemic is ongoing, a suspected case can be any individual aged 5 years or more presenting with acute watery diarrhoea, with or without vomiting."}, {"prompt": "What is the standard case definition for a confirmed case of Cholera? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case where Vibrio cholerae O1 or O139 has been isolated from the stool."}, {"prompt": "How is a confirmed case of Cholera defined? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case where Vibrio cholerae O1 or O139 has been isolated from the stool."}, {"prompt": "What are the criteria for confirming a case of Cholera? related to Yellow Fever Disease", "completion": "A confirmed case is a suspected case where Vibrio cholerae O1 or O139 has been isolated from the stool."}, {"prompt": "How to respond if Cholera cases are suspected? related to Yellow Fever Disease", "completion": "Immediate reporting of case-based information is crucial. The patient should be managed and treated according to national guidelines. Strict hand-washing and isolation procedures should be enhanced. A case-based investigation should be conducted to identify similar unreported cases. A stool specimen should be obtained from 5 patients within 5 days of onset of acute watery diarrhoea, before starting antibiotic treatment."}, {"prompt": "What actions should be taken if Cholera cases are suspected? related to Yellow Fever Disease", "completion": "Immediate reporting of case-based information is crucial. The patient should be managed and treated according to national guidelines. Strict hand-washing and isolation procedures should be enhanced. A case-based investigation should be conducted to identify similar unreported cases. A stool specimen should be obtained from 5 patients within 5 days of onset of acute watery diarrhoea, before starting antibiotic treatment."}, {"prompt": "How to respond if Cholera cases meet the alert threshold? related to Yellow Fever Disease", "completion": "Immediate reporting of case-based information is crucial. The patient should be managed and treated according to national guidelines. Strict hand-washing and isolation procedures should be enhanced. A case-based investigation should be conducted to identify similar unreported cases. A stool specimen should be obtained from 5 patients within 5 days of onset of acute watery diarrhoea, before starting antibiotic treatment."}, {"prompt": "What actions should be taken if Cholera cases meet the action threshold? related to Yellow Fever Disease", "completion": "Set up a treatment centre in the locality where cases are identified. Patients should be treated on-site rather than being referred to distant treatment centres. Strengthen case management and treatment. Engage the community early for rapid case detection and treatment. Check the availability of clean drinking water. Limit large gatherings, especially during an epidemic. Reduce sporadic and outbreak-related cases through continuous access to safe water and promote safe food preparation. Also, promote the safe disposal of human waste."}, {"prompt": "What steps should be taken if Cholera cases meet the action threshold? related to Yellow Fever Disease", "completion": "Set up a treatment centre in the locality where cases are identified. Patients should be treated on-site rather than being referred to distant treatment centres. Strengthen case management and treatment. Engage the community early for rapid case detection and treatment. Check the availability of clean drinking water. Limit large gatherings, especially during an epidemic. Reduce sporadic and outbreak-related cases through continuous access to safe water and promote safe food preparation. Also, promote the safe disposal of human waste."}, {"prompt": "How should data about individuals with Cholera be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Weekly total cases and deaths should be counted for sporadic cases and during outbreaks. Analyze the distribution of cases by age and according to sources of drinking water. Assess risk factors to enhance control of sporadic cases and outbreaks."}, {"prompt": "What are the methods for analyzing data about individuals with Cholera? related to Yellow Fever Disease", "completion": "Weekly total cases and deaths should be counted for sporadic cases and during outbreaks. Analyze the distribution of cases by age and according to sources of drinking water. Assess risk factors to enhance control of sporadic cases and outbreaks."}, {"prompt": "How can we interpret the data on individuals with Cholera? related to Yellow Fever Disease", "completion": "Weekly total cases and deaths should be counted for sporadic cases and during outbreaks. Analyze the distribution of cases by age and according to sources of drinking water. Assess risk factors to enhance control of sporadic cases and outbreaks."}, {"prompt": "How to analyze and interpret data about time in the context of Cholera? related to Yellow Fever Disease", "completion": "Weekly cases and deaths should be graphed, and an epidemic curve should be constructed during outbreaks. Immediate case-based information should be reported, and summary information should be provided monthly for routine surveillance."}, {"prompt": "What are the techniques used for temporal analysis of Cholera cases? related to Yellow Fever Disease", "completion": "Weekly cases and deaths should be graphed, and an epidemic curve should be constructed during outbreaks. Immediate case-based information should be reported, and summary information should be provided monthly for routine surveillance."}, {"prompt": "How can temporal analysis help in understanding Cholera trends? related to Yellow Fever Disease", "completion": "Weekly cases and deaths should be graphed, and an epidemic curve should be constructed during outbreaks. Immediate case-based information should be reported, and summary information should be provided monthly for routine surveillance."}, {"prompt": "How to analyze and interpret data about place in the context of Cholera? related to Yellow Fever Disease", "completion": "The location of case households should be plotted precisely."}, {"prompt": "What are the methods used for spatial analysis of Cholera cases? related to Yellow Fever Disease", "completion": "The location of case households should be plotted precisely."}, {"prompt": "How can spatial analysis contribute to understanding Cholera transmission? related to Yellow Fever Disease", "completion": "The location of case households should be plotted precisely."}, {"prompt": "What are the references for Cholera? related to Yellow Fever Disease", "completion": "1. Management of the patient with cholera, World Health Organization, 1992. WHO/CDD/SER/91.15 Rev1 (1992)\n2. Epidemic diarrhoeal disease preparedness and response--Training and practice. Facilitator and participant manuals. World Health Organization, 1997. WHO/EMC/DIS/97.3 and WHO/EMC/DIS/97.6\n3. Laboratory Methods for the Diagnosis of Epidemic Dysentery and Cholera. CDC/WHO, 1999. CDC, Atlanta, GA, USA"}, {"prompt": "What are the recommended resources for Cholera? related to Yellow Fever Disease", "completion": "1. Management of the patient with cholera, World Health Organization, 1992. WHO/CDD/SER/91.15 Rev1 (1992)\n2. Epidemic diarrhoeal disease preparedness and response--Training and practice. Facilitator and participant manuals. World Health Organization, 1997. WHO/EMC/DIS/97.3 and WHO/EMC/DIS/97.6\n3. Laboratory Methods for the Diagnosis of Epidemic Dysentery and Cholera. CDC/WHO, 1999. CDC, Atlanta, GA, USA"}, {"prompt": "Where can I find more information on Cholera? related to Yellow Fever Disease", "completion": "1. Management of the patient with cholera, World Health Organization, 1992. WHO/CDD/SER/91.15 Rev1 (1992)\n2. Epidemic diarrhoeal disease preparedness and response--Training and practice. Facilitator and participant manuals. World Health Organization, 1997. WHO/EMC/DIS/97.3 and WHO/EMC/DIS/97.6\n3. Laboratory Methods for the Diagnosis of Epidemic Dysentery and Cholera. CDC/WHO, 1999. CDC, Atlanta, GA, USA"}, {"prompt": "Explain Chikungunya. related to Yellow Fever Disease", "completion": "Chikungunya fever is a viral illness that is spread by the bite of infected mosquitoes. The disease resembles dengue fever, and is characterized by severe, sometimes persistent, joint pain (arthritis), as well as fever and rash. It is rarely life-threatening. Nevertheless, widespread occurrence of diseases causes substantial morbidity and economic loss. The word chikungunya is Makonde for that which bends up, in reference to the stooped posture of patients afflicted with the severe joint pain associated with the disease. Epidemics of fever, rash and arthritis, resembling Chikungunya fever were recorded as early as 1779. However, the virus was first isolated between 1952-1953 from both man and mosquitoes during an epidemic, in Tanzania. Chikungunya fever historically displayed interesting epidemiological profiles in that: major epidemics appeared and disappeared cyclically, usually with an inter-epidemic period of 7-8 years and sometimes as long as 20 years. After a long period of absence, outbreaks appeared in Indonesia in 1999 and have been virtually ongoing since 2004."}, {"prompt": "Describe Chikungunya. related to Yellow Fever Disease", "completion": "Chikungunya fever is a viral illness that is spread by the bite of infected mosquitoes. The disease resembles dengue fever, and is characterized by severe, sometimes persistent, joint pain (arthritis), as well as fever and rash. It is rarely life-threatening. Nevertheless, widespread occurrence of diseases causes substantial morbidity and economic loss. The word chikungunya is Makonde for that which bends up, in reference to the stooped posture of patients afflicted with the severe joint pain associated with the disease. Epidemics of fever, rash and arthritis, resembling Chikungunya fever were recorded as early as 1779. However, the virus was first isolated between 1952-1953 from both man and mosquitoes during an epidemic, in Tanzania. Chikungunya fever historically displayed interesting epidemiological profiles in that: major epidemics appeared and disappeared cyclically, usually with an inter-epidemic period of 7-8 years and sometimes as long as 20 years. After a long period of absence, outbreaks appeared in Indonesia in 1999 and have been virtually ongoing since 2004."}, {"prompt": "Elaborate on Chikungunya. related to Yellow Fever Disease", "completion": "Chikungunya fever is a viral illness that is spread by the bite of infected mosquitoes. The disease resembles dengue fever, and is characterized by severe, sometimes persistent, joint pain (arthritis), as well as fever and rash. It is rarely life-threatening. Nevertheless, widespread occurrence of diseases causes substantial morbidity and economic loss. The word chikungunya is Makonde for that which bends up, in reference to the stooped posture of patients afflicted with the severe joint pain associated with the disease. Epidemics of fever, rash and arthritis, resembling Chikungunya fever were recorded as early as 1779. However, the virus was first isolated between 1952-1953 from both man and mosquitoes during an epidemic, in Tanzania. Chikungunya fever historically displayed interesting epidemiological profiles in that: major epidemics appeared and disappeared cyclically, usually with an inter-epidemic period of 7-8 years and sometimes as long as 20 years. After a long period of absence, outbreaks appeared in Indonesia in 1999 and have been virtually ongoing since 2004."}, {"prompt": "Define Chikungunya. related to Yellow Fever Disease", "completion": "Chikungunya fever is a viral illness that is spread by the bite of infected mosquitoes. The disease resembles dengue fever, and is characterized by severe, sometimes persistent, joint pain (arthritis), as well as fever and rash. It is rarely life-threatening. Nevertheless, widespread occurrence of diseases causes substantial morbidity and economic loss. The word chikungunya is Makonde for that which bends up, in reference to the stooped posture of patients afflicted with the severe joint pain associated with the disease. Epidemics of fever, rash and arthritis, resembling Chikungunya fever were recorded as early as 1779. However, the virus was first isolated between 1952-1953 from both man and mosquitoes during an epidemic, in Tanzania. Chikungunya fever historically displayed interesting epidemiological profiles in that: major epidemics appeared and disappeared cyclically, usually with an inter-epidemic period of 7-8 years and sometimes as long as 20 years. After a long period of absence, outbreaks appeared in Indonesia in 1999 and have been virtually ongoing since 2004."}, {"prompt": "What is the nature of Chikungunya? related to Yellow Fever Disease", "completion": "Chikungunya fever is a viral illness that is spread by the bite of infected mosquitoes. The disease resembles dengue fever, and is characterized by severe, sometimes persistent, joint pain (arthritis), as well as fever and rash. It is rarely life-threatening. Nevertheless, widespread occurrence of diseases causes substantial morbidity and economic loss. The word chikungunya is Makonde for that which bends up, in reference to the stooped posture of patients afflicted with the severe joint pain associated with the disease. Epidemics of fever, rash and arthritis, resembling Chikungunya fever were recorded as early as 1779. However, the virus was first isolated between 1952-1953 from both man and mosquitoes during an epidemic, in Tanzania. Chikungunya fever historically displayed interesting epidemiological profiles in that: major epidemics appeared and disappeared cyclically, usually with an inter-epidemic period of 7-8 years and sometimes as long as 20 years. After a long period of absence, outbreaks appeared in Indonesia in 1999 and have been virtually ongoing since 2004."}, {"prompt": "What is the surveillance objective for Chikungunya? related to Yellow Fever Disease", "completion": "Detect chikungunya sporadic cases and outbreaks promptly, and seek laboratory verification. Identify high risk areas in order to improve prevention of outbreaks by taking steps to avoid mosquito bites and elimination of breeding sites."}, {"prompt": "What are the goals of Chikungunya surveillance? related to Yellow Fever Disease", "completion": "Detect chikungunya sporadic cases and outbreaks promptly, and seek laboratory verification. Identify high risk areas in order to improve prevention of outbreaks by taking steps to avoid mosquito bites and elimination of breeding sites."}, {"prompt": "What is the objective of Chikungunya surveillance? related to Yellow Fever Disease", "completion": "Detect chikungunya sporadic cases and outbreaks promptly, and seek laboratory verification. Identify high risk areas in order to improve prevention of outbreaks by taking steps to avoid mosquito bites and elimination of breeding sites."}, {"prompt": "What is the standard case definition for a suspected case of Chikungunya? related to Yellow Fever Disease", "completion": "Any person with acute onset of fever >38.5\u00b0C and severe arthralgia/arthritis not explained by other medical conditions."}, {"prompt": "When should a person be considered as a suspected case of Chikungunya? related to Yellow Fever Disease", "completion": "Any person with acute onset of fever >38.5\u00b0C and severe arthralgia/arthritis not explained by other medical conditions."}, {"prompt": "What conditions should be met for considering a person as a suspected case of Chikungunya? related to Yellow Fever Disease", "completion": "Any person with acute onset of fever >38.5\u00b0C and severe arthralgia/arthritis not explained by other medical conditions."}, {"prompt": "What is the standard case definition for a confirmed case of Chikungunya? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation."}, {"prompt": "How is a confirmed case of Chikungunya defined? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation."}, {"prompt": "Under what circumstances can a Chikungunya case be confirmed? related to Yellow Fever Disease", "completion": "A suspected case with laboratory confirmation."}, {"prompt": "How to respond to alert threshold if Chikungunya cases are suspected? related to Yellow Fever Disease", "completion": "If chikungunya cases are suspected: Report case-based information immediately to the next level. Collect specimens for confirming the cases. Conduct an investigation to determine the risk factors for transmission. Manage and treat the cases using anti-inflammatory agents."}, {"prompt": "What actions should be taken in response to suspected Chikungunya cases? related to Yellow Fever Disease", "completion": "If chikungunya cases are suspected: Report case-based information immediately to the next level. Collect specimens for confirming the cases. Conduct an investigation to determine the risk factors for transmission. Manage and treat the cases using anti-inflammatory agents."}, {"prompt": "What measures should be taken if Chikungunya cases are suspected? related to Yellow Fever Disease", "completion": "If chikungunya cases are suspected: Report case-based information immediately to the next level. Collect specimens for confirming the cases. Conduct an investigation to determine the risk factors for transmission. Manage and treat the cases using anti-inflammatory agents."}, {"prompt": "How to respond to action threshold if Chikungunya cases are confirmed? related to Yellow Fever Disease", "completion": "Symptomatic treatment for mitigating pain and fever using anti-inflammatory drugs along with rest usually suffices. Persistent joint pain may require analgesic and long-term anti-inflammatory therapy. Prevention is entirely dependent upon taking steps to avoid mosquito bites and elimination of mosquito breeding sites. To avoid mosquito bites: Wear full sleeve clothes and long dresses to cover the limbs. Use mosquito coils and repellents. Use mosquito nets - to protect babies, old people and others, who may rest during the day. The effectiveness of such nets can be improved by treating them with permethrin (pyrethroid insecticide). Curtains (cloth or bamboo) can also be treated with insecticide and hung at windows or doorways, to repel or kill mosquitoes. Mosquitoes become infected when they bite people who are sick with chikungunya. Mosquito nets and mosquito coils will help prevent mosquitoes from biting sick people."}, {"prompt": "What actions should be taken if Chikungunya cases are confirmed? related to Yellow Fever Disease", "completion": "Symptomatic treatment for mitigating pain and fever using anti-inflammatory drugs along with rest usually suffices. Persistent joint pain may require analgesic and long-term anti-inflammatory therapy. Prevention is entirely dependent upon taking steps to avoid mosquito bites and elimination of mosquito breeding sites. To avoid mosquito bites: Wear full sleeve clothes and long dresses to cover the limbs. Use mosquito coils and repellents. Use mosquito nets - to protect babies, old people and others, who may rest during the day. The effectiveness of such nets can be improved by treating them with permethrin (pyrethroid insecticide). Curtains (cloth or bamboo) can also be treated with insecticide and hung at windows or doorways, to repel or kill mosquitoes. Mosquitoes become infected when they bite people who are sick with chikungunya. Mosquito nets and mosquito coils will help prevent mosquitoes from biting sick people."}, {"prompt": "How to respond to confirmed Chikungunya cases? related to Yellow Fever Disease", "completion": "Symptomatic treatment for mitigating pain and fever using anti-inflammatory drugs along with rest usually suffices. Persistent joint pain may require analgesic and long-term anti-inflammatory therapy. Prevention is entirely dependent upon taking steps to avoid mosquito bites and elimination of mosquito breeding sites. To avoid mosquito bites: Wear full sleeve clothes and long dresses to cover the limbs. Use mosquito coils and repellents. Use mosquito nets - to protect babies, old people and others, who may rest during the day. The effectiveness of such nets can be improved by treating them with permethrin (pyrethroid insecticide). Curtains (cloth or bamboo) can also be treated with insecticide and hung at windows or doorways, to repel or kill mosquitoes. Mosquitoes become infected when they bite people who are sick with chikungunya. Mosquito nets and mosquito coils will help prevent mosquitoes from biting sick people."}, {"prompt": "How to analyze and interpret data about a person with Chikungunya? related to Yellow Fever Disease", "completion": "Report immediate case-based information for cases and deaths. Report summary totals monthly. During outbreak, count cases and deaths weekly. Analyze by age. Assess risk factors to improve prevention of outbreaks."}, {"prompt": "How should data about individuals with Chikungunya be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Report immediate case-based information for cases and deaths. Report summary totals monthly. During outbreak, count cases and deaths weekly. Analyze by age. Assess risk factors to improve prevention of outbreaks."}, {"prompt": "What are the methods for analyzing and interpreting data about a person with Chikungunya? related to Yellow Fever Disease", "completion": "Report immediate case-based information for cases and deaths. Report summary totals monthly. During outbreak, count cases and deaths weekly. Analyze by age. Assess risk factors to improve prevention of outbreaks."}, {"prompt": "How to analyze and interpret data about time in the context of Chikungunya? related to Yellow Fever Disease", "completion": "Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "What methods are used for temporal analysis of Chikungunya cases? related to Yellow Fever Disease", "completion": "Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "How can temporal analysis help in understanding Chikungunya trends? related to Yellow Fever Disease", "completion": "Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "How to analyze and interpret data about place in the context of Chikungunya? related to Yellow Fever Disease", "completion": "Plot location of case households with precise mapping."}, {"prompt": "What methods are used for spatial analysis of Chikungunya cases? related to Yellow Fever Disease", "completion": "Plot location of case households with precise mapping."}, {"prompt": "How can spatial analysis contribute to understanding Chikungunya transmission? related to Yellow Fever Disease", "completion": "Plot location of case households with precise mapping."}, {"prompt": "Where can I find more information about Chikungunya? related to Yellow Fever Disease", "completion": "1. Weekly Epidemiological Record N\u00b0 1, 2005, 80, 1-8; http://www.who.int/wer\n2. World Health Organization http://www.who.int/mediacentre/factsheets/fs327/en/\n3. United States, Centers for Disease Control http://www.cdc.gov/ncidod/dvbid/chikungunya/\n4. Sergon et al. Seroprevalence of Chikungunya Virus (CHIKV) Infection on Lamu Island, Kenya, October 2004. Am J Trop Med Hyg. 2008 Feb;78(2):333-337\n5. Powers et al. Evolutionary relationships and systematics of the alphaviruses. J Virol. 2001 Nov;75(21):10118-31"}, {"prompt": "What are some reliable sources of information on Chikungunya? related to Yellow Fever Disease", "completion": "1. Weekly Epidemiological Record N\u00b0 1, 2005, 80, 1-8; http://www.who.int/wer\n2. World Health Organization http://www.who.int/mediacentre/factsheets/fs327/en/\n3. United States, Centers for Disease Control http://www.cdc.gov/ncidod/dvbid/chikungunya/\n4. Sergon et al. Seroprevalence of Chikungunya Virus (CHIKV) Infection on Lamu Island, Kenya, October 2004. Am J Trop Med Hyg. 2008 Feb;78(2):333-337\n5. Powers et al. Evolutionary relationships and systematics of the alphaviruses. J Virol. 2001 Nov;75(21):10118-31"}, {"prompt": "Where can I find official references regarding Chikungunya? related to Yellow Fever Disease", "completion": "1. Weekly Epidemiological Record N\u00b0 1, 2005, 80, 1-8; http://www.who.int/wer\n2. World Health Organization http://www.who.int/mediacentre/factsheets/fs327/en/\n3. United States, Centers for Disease Control http://www.cdc.gov/ncidod/dvbid/chikungunya/\n4. Sergon et al. Seroprevalence of Chikungunya Virus (CHIKV) Infection on Lamu Island, Kenya, October 2004. Am J Trop Med Hyg. 2008 Feb;78(2):333-337\n5. Powers et al. Evolutionary relationships and systematics of the alphaviruses. J Virol. 2001 Nov;75(21):10118-31"}, {"prompt": "Explain Buruli ulcer (Mycobacterium ulcerans disease). related to Yellow Fever Disease", "completion": "Skin infection caused by Mycobacterium ulcerans (an AFB). Occurring mainly as skin lesions (nodules, plaques and ulcers) than can be complicated by bone and joint involvement. Involvement of other organs like the eyes is rare. Spreading in inter-tropical areas, in swampy soils or water body surroundings, forestry or surface mining zones. Patients are classified into three categories: Category I: patient with a single lesion which size is less than 5 cm of diameter (early lesion). Category II: patient with single lesion which size is between 5 and 15 cm of diameter. Category III: patient single lesion which size is over 15 cm of diameter or with multiple lesions or lesion located in critical site (face, head & neck, breast, perineum, genitalia, lesion spanning over joints). BU case management has improved greatly through use of WHO recommended antibiotics (rifampicin and streptomycin) in 2004. Surgery is still needed for late cases (category III). Cumulative number of cases is over 60000 in 2009. Mode of transmission is still unknown. M ulcerans could penetrate the skin through insect bite (water bugs); micro trauma or small wounds. Confirmation of diagnosis is done by PCR, AFB search with ZN staining, culture or histology. Specimens of lesions are taken by swab in ulcer, fine needle aspiration (FNA) or biopsy in case of surgery."}, {"prompt": "Describe Buruli ulcer (Mycobacterium ulcerans disease). related to Yellow Fever Disease", "completion": "Skin infection caused by Mycobacterium ulcerans (an AFB). Occurring mainly as skin lesions (nodules, plaques and ulcers) than can be complicated by bone and joint involvement. Involvement of other organs like the eyes is rare. Spreading in inter-tropical areas, in swampy soils or water body surroundings, forestry or surface mining zones. Patients are classified into three categories: Category I: patient with a single lesion which size is less than 5 cm of diameter (early lesion). Category II: patient with single lesion which size is between 5 and 15 cm of diameter. Category III: patient single lesion which size is over 15 cm of diameter or with multiple lesions or lesion located in critical site (face, head & neck, breast, perineum, genitalia, lesion spanning over joints). BU case management has improved greatly through use of WHO recommended antibiotics (rifampicin and streptomycin) in 2004. Surgery is still needed for late cases (category III). Cumulative number of cases is over 60000 in 2009. Mode of transmission is still unknown. M ulcerans could penetrate the skin through insect bite (water bugs); micro trauma or small wounds. Confirmation of diagnosis is done by PCR, AFB search with ZN staining, culture or histology. Specimens of lesions are taken by swab in ulcer, fine needle aspiration (FNA) or biopsy in case of surgery."}, {"prompt": "Elaborate on Buruli ulcer (Mycobacterium ulcerans disease). related to Yellow Fever Disease", "completion": "Skin infection caused by Mycobacterium ulcerans (an AFB). Occurring mainly as skin lesions (nodules, plaques and ulcers) than can be complicated by bone and joint involvement. Involvement of other organs like the eyes is rare. Spreading in inter-tropical areas, in swampy soils or water body surroundings, forestry or surface mining zones. Patients are classified into three categories: Category I: patient with a single lesion which size is less than 5 cm of diameter (early lesion). Category II: patient with single lesion which size is between 5 and 15 cm of diameter. Category III: patient single lesion which size is over 15 cm of diameter or with multiple lesions or lesion located in critical site (face, head & neck, breast, perineum, genitalia, lesion spanning over joints). BU case management has improved greatly through use of WHO recommended antibiotics (rifampicin and streptomycin) in 2004. Surgery is still needed for late cases (category III). Cumulative number of cases is over 60000 in 2009. Mode of transmission is still unknown. M ulcerans could penetrate the skin through insect bite (water bugs); micro trauma or small wounds. Confirmation of diagnosis is done by PCR, AFB search with ZN staining, culture or histology. Specimens of lesions are taken by swab in ulcer, fine needle aspiration (FNA) or biopsy in case of surgery."}, {"prompt": "Define Buruli ulcer (Mycobacterium ulcerans disease). related to Yellow Fever Disease", "completion": "Skin infection caused by Mycobacterium ulcerans (an AFB). Occurring mainly as skin lesions (nodules, plaques and ulcers) than can be complicated by bone and joint involvement. Involvement of other organs like the eyes is rare. Spreading in inter-tropical areas, in swampy soils or water body surroundings, forestry or surface mining zones. Patients are classified into three categories: Category I: patient with a single lesion which size is less than 5 cm of diameter (early lesion). Category II: patient with single lesion which size is between 5 and 15 cm of diameter. Category III: patient single lesion which size is over 15 cm of diameter or with multiple lesions or lesion located in critical site (face, head & neck, breast, perineum, genitalia, lesion spanning over joints). BU case management has improved greatly through use of WHO recommended antibiotics (rifampicin and streptomycin) in 2004. Surgery is still needed for late cases (category III). Cumulative number of cases is over 60000 in 2009. Mode of transmission is still unknown. M ulcerans could penetrate the skin through insect bite (water bugs); micro trauma or small wounds. Confirmation of diagnosis is done by PCR, AFB search with ZN staining, culture or histology. Specimens of lesions are taken by swab in ulcer, fine needle aspiration (FNA) or biopsy in case of surgery."}, {"prompt": "What is Mycobacterium ulcerans disease (Buruli ulcer)? related to Yellow Fever Disease", "completion": "Skin infection caused by Mycobacterium ulcerans (an AFB). Occurring mainly as skin lesions (nodules, plaques and ulcers) than can be complicated by bone and joint involvement. Involvement of other organs like the eyes is rare. Spreading in inter-tropical areas, in swampy soils or water body surroundings, forestry or surface mining zones. Patients are classified into three categories: Category I: patient with a single lesion which size is less than 5 cm of diameter (early lesion). Category II: patient with single lesion which size is between 5 and 15 cm of diameter. Category III: patient single lesion which size is over 15 cm of diameter or with multiple lesions or lesion located in critical site (face, head & neck, breast, perineum, genitalia, lesion spanning over joints). BU case management has improved greatly through use of WHO recommended antibiotics (rifampicin and streptomycin) in 2004. Surgery is still needed for late cases (category III). Cumulative number of cases is over 60000 in 2009. Mode of transmission is still unknown. M ulcerans could penetrate the skin through insect bite (water bugs); micro trauma or small wounds. Confirmation of diagnosis is done by PCR, AFB search with ZN staining, culture or histology. Specimens of lesions are taken by swab in ulcer, fine needle aspiration (FNA) or biopsy in case of surgery."}, {"prompt": "What is the primary goal of Buruli ulcer (Mycobacterium ulcerans disease) surveillance? related to Yellow Fever Disease", "completion": "Geographical distribution of the disease to locate endemic areas and districts and focus early case finding, proper management with WHO recommended antibiotics and prevention of disabilities"}, {"prompt": "What is the main purpose of Buruli ulcer (Mycobacterium ulcerans disease) surveillance? related to Yellow Fever Disease", "completion": "Geographical distribution of the disease to locate endemic areas and districts and focus early case finding, proper management with WHO recommended antibiotics and prevention of disabilities"}, {"prompt": "What is the primary aim of Buruli ulcer (Mycobacterium ulcerans disease) surveillance? related to Yellow Fever Disease", "completion": "Geographical distribution of the disease to locate endemic areas and districts and focus early case finding, proper management with WHO recommended antibiotics and prevention of disabilities"}, {"prompt": "What is the primary objective of Buruli ulcer (Mycobacterium ulcerans disease) surveillance? related to Yellow Fever Disease", "completion": "Geographical distribution of the disease to locate endemic areas and districts and focus early case finding, proper management with WHO recommended antibiotics and prevention of disabilities"}, {"prompt": "What is the case definition for a suspected case of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "A person presenting a painless skin nodule, plaque or ulcer, living or having visited a BU endemic area"}, {"prompt": "How is a suspected case of Buruli ulcer (Mycobacterium ulcerans disease) defined? related to Yellow Fever Disease", "completion": "A person presenting a painless skin nodule, plaque or ulcer, living or having visited a BU endemic area"}, {"prompt": "What criteria are used to define a suspected case of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "A person presenting a painless skin nodule, plaque or ulcer, living or having visited a BU endemic area"}, {"prompt": "When is a case considered a suspected case of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "A person presenting a painless skin nodule, plaque or ulcer, living or having visited a BU endemic area"}, {"prompt": "What is the case definition for a confirmed case of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "A suspected case confirmed by at least one laboratory test (ZN for AFB, PCR, culture or histology)"}, {"prompt": "How is a confirmed case of Buruli ulcer (Mycobacterium ulcerans disease) defined? related to Yellow Fever Disease", "completion": "A suspected case confirmed by at least one laboratory test (ZN for AFB, PCR, culture or histology)"}, {"prompt": "What criteria are used to define a confirmed case of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "A suspected case confirmed by at least one laboratory test (ZN for AFB, PCR, culture or histology)"}, {"prompt": "When is a case considered a confirmed case of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "A suspected case confirmed by at least one laboratory test (ZN for AFB, PCR, culture or histology)"}, {"prompt": "How to respond if Buruli ulcer (Mycobacterium ulcerans disease) cases are suspected? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report the suspected case to the appropriate level of the health system. At health facility level: Take a specimen for laboratory confirmation (Swab or FNA). Begin wound dressing and combined antibiotic treatment with: Rifampicin 10 mg/kg daily oral intake for 8 weeks (56 days). Streptomycin daily injection for 8 weeks (56 days). Refer category III patients to reference hospital/centre. Fill in case report form (BU 01 or BU 02) with origin village GPS data and report to Health District, Regional and National levels. Search other cases in origin village of confirmed case of BU"}, {"prompt": "What should be done if Buruli ulcer (Mycobacterium ulcerans disease) cases are suspected? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report the suspected case to the appropriate level of the health system. At health facility level: Take a specimen for laboratory confirmation (Swab or FNA). Begin wound dressing and combined antibiotic treatment with: Rifampicin 10 mg/kg daily oral intake for 8 weeks (56 days). Streptomycin daily injection for 8 weeks (56 days). Refer category III patients to reference hospital/centre. Fill in case report form (BU 01 or BU 02) with origin village GPS data and report to Health District, Regional and National levels. Search other cases in origin village of confirmed case of BU"}, {"prompt": "How to handle suspected cases of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report the suspected case to the appropriate level of the health system. At health facility level: Take a specimen for laboratory confirmation (Swab or FNA). Begin wound dressing and combined antibiotic treatment with: Rifampicin 10 mg/kg daily oral intake for 8 weeks (56 days). Streptomycin daily injection for 8 weeks (56 days). Refer category III patients to reference hospital/centre. Fill in case report form (BU 01 or BU 02) with origin village GPS data and report to Health District, Regional and National levels. Search other cases in origin village of confirmed case of BU"}, {"prompt": "How to respond if confirmed cases of Buruli ulcer (Mycobacterium ulcerans disease) are detected? related to Yellow Fever Disease", "completion": "Not applicable to BU"}, {"prompt": "What should be done if Buruli ulcer (Mycobacterium ulcerans disease) cases are confirmed? related to Yellow Fever Disease", "completion": "Not applicable to BU"}, {"prompt": "How to analyze and interpret data about individuals with Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Count newly detected cases monthly by category of patients (Cat I, II or III). Analyze age and disability distribution and treatment outcomes (cases cured, cured without limitation of movement or amputation, relapse after recommended antibiotic treatment)."}, {"prompt": "How to interpret data about individuals with Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Count newly detected cases monthly by category of patients (Cat I, II or III). Analyze age and disability distribution and treatment outcomes (cases cured, cured without limitation of movement or amputation, relapse after recommended antibiotic treatment)."}, {"prompt": "What is the process of analyzing data about individuals with Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Count newly detected cases monthly by category of patients (Cat I, II or III). Analyze age and disability distribution and treatment outcomes (cases cured, cured without limitation of movement or amputation, relapse after recommended antibiotic treatment)."}, {"prompt": "How to analyze and interpret data about time in the context of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Graph of cases by year of diagnosis, graph of cumulative number of cases."}, {"prompt": "What is the method for analyzing data about time in the context of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Graph of cases by year of diagnosis, graph of cumulative number of cases."}, {"prompt": "How to interpret data about time in the context of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Graph of cases by year of diagnosis, graph of cumulative number of cases."}, {"prompt": "How is data about time in the context of Buruli ulcer (Mycobacterium ulcerans disease) analyzed? related to Yellow Fever Disease", "completion": "Graph of cases by year of diagnosis, graph of cumulative number of cases."}, {"prompt": "How to analyze and interpret data about place in the context of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Plot cases by location of households and colour shade endemic districts"}, {"prompt": "What is the process of analyzing data about place in the context of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Plot cases by location of households and colour shade endemic districts"}, {"prompt": "How to interpret data about place in the context of Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "Plot cases by location of households and colour shade endemic districts"}, {"prompt": "How is data about place in the context of Buruli ulcer (Mycobacterium ulcerans disease) analyzed? related to Yellow Fever Disease", "completion": "Plot cases by location of households and colour shade endemic districts"}, {"prompt": "What are the sources of reference for Buruli ulcer (Mycobacterium ulcerans disease)? related to Yellow Fever Disease", "completion": "1. Resolution WHA 57.1 on surveillance and control of Mycobacterium ulcerans disease.(Buruli ulcer), In: 57th World Health Assembly, Geneva, 17-22 May 2004; Resolutions and decisions, annexes. Geneva, WHO; 2004 (WHA57/2004/REC/1: 1-2)\n2. Provisional guidance on the role of specific antibiotics in the management of Mycobacterium ulcerans disease (Buruli ulcer) WHO/CDS/CPE/GBUI/2004.10\n3. Buruli ulcer: First programme review meeting for West Africa - Summary report, WHO, WER, 6; 2009 : 43-48\n4. Control of Communicable Diseases Manual, 18th Edition.\n5. District Laboratory Practice in Tropical countries, Cambridge.\n6. Ulcere de Buruli , prise en charge de l'infection a Mycobacterium ulcerans"}, {"prompt": "Explain Anthrax (human). related to Yellow Fever Disease", "completion": "Anthrax is a widespread zoonotic disease caused by the spore-forming bacterium Bacillus anthracis, a Gram positive rod-shaped bacterium. A. It is transmitted from infected domestic livestock (cattle, sheep, goats, buffaloes, pigs and others) or wild game animals to humans by direct contact or indirect contact with animals or their products. The incubation period typically ranges from 1 to 7 days, but may be longer (up to two to three weeks for cutaneous anthrax and up to 42 days for inhalation anthrax). Persons exposed to occupational hazards include those handling infected carcasses and those employed in the processing of bones, hides, wool and other animal products. Persons may also become infected by handling or consuming meat from animals that are sick with or have died of the disease. Biting flies have been reported to transmit the disease from infected animals to humans however how readily or often this occurs is unknown. Human anthrax is a serious problem in several countries and has potential for explosive outbreaks (especially the gastrointestinal form that is contracted from eating infected meat); while pulmonary (inhalation) anthrax is mainly occupational, the threat of biological warfare attacks should not be forgotten. Anthrax has a serious impact on the trade of animal products. The control of anthrax is based on its prevention in livestock. Programmes based only on prevention in humans are costly and likely to be ineffective except for those industrially exposed. There is an effective vaccine for those persons considered at risk for occupational exposure, and successful vaccines are used for livestock, particularly for herds with ongoing exposure to contaminated soil or vegetation. In most countries anthrax is a notifiable disease."}, {"prompt": "Describe Anthrax (human). related to Yellow Fever Disease", "completion": "Anthrax is a widespread zoonotic disease caused by the spore-forming bacterium Bacillus anthracis, a Gram positive rod-shaped bacterium. A. It is transmitted from infected domestic livestock (cattle, sheep, goats, buffaloes, pigs and others) or wild game animals to humans by direct contact or indirect contact with animals or their products. The incubation period typically ranges from 1 to 7 days, but may be longer (up to two to three weeks for cutaneous anthrax and up to 42 days for inhalation anthrax). Persons exposed to occupational hazards include those handling infected carcasses and those employed in the processing of bones, hides, wool and other animal products. Persons may also become infected by handling or consuming meat from animals that are sick with or have died of the disease. Biting flies have been reported to transmit the disease from infected animals to humans however how readily or often this occurs is unknown. Human anthrax is a serious problem in several countries and has potential for explosive outbreaks (especially the gastrointestinal form that is contracted from eating infected meat); while pulmonary (inhalation) anthrax is mainly occupational, the threat of biological warfare attacks should not be forgotten. Anthrax has a serious impact on the trade of animal products. The control of anthrax is based on its prevention in livestock. Programmes based only on prevention in humans are costly and likely to be ineffective except for those industrially exposed. There is an effective vaccine for those persons considered at risk for occupational exposure, and successful vaccines are used for livestock, particularly for herds with ongoing exposure to contaminated soil or vegetation. In most countries anthrax is a notifiable disease."}, {"prompt": "Elaborate on Anthrax (human). related to Yellow Fever Disease", "completion": "Anthrax is a widespread zoonotic disease caused by the spore-forming bacterium Bacillus anthracis, a Gram positive rod-shaped bacterium. A. It is transmitted from infected domestic livestock (cattle, sheep, goats, buffaloes, pigs and others) or wild game animals to humans by direct contact or indirect contact with animals or their products. The incubation period typically ranges from 1 to 7 days, but may be longer (up to two to three weeks for cutaneous anthrax and up to 42 days for inhalation anthrax). Persons exposed to occupational hazards include those handling infected carcasses and those employed in the processing of bones, hides, wool and other animal products. Persons may also become infected by handling or consuming meat from animals that are sick with or have died of the disease. Biting flies have been reported to transmit the disease from infected animals to humans however how readily or often this occurs is unknown. Human anthrax is a serious problem in several countries and has potential for explosive outbreaks (especially the gastrointestinal form that is contracted from eating infected meat); while pulmonary (inhalation) anthrax is mainly occupational, the threat of biological warfare attacks should not be forgotten. Anthrax has a serious impact on the trade of animal products. The control of anthrax is based on its prevention in livestock. Programmes based only on prevention in humans are costly and likely to be ineffective except for those industrially exposed. There is an effective vaccine for those persons considered at risk for occupational exposure, and successful vaccines are used for livestock, particularly for herds with ongoing exposure to contaminated soil or vegetation. In most countries anthrax is a notifiable disease."}, {"prompt": "Define Anthrax (human). related to Yellow Fever Disease", "completion": "Anthrax is a widespread zoonotic disease caused by the spore-forming bacterium Bacillus anthracis, a Gram positive rod-shaped bacterium. A. It is transmitted from infected domestic livestock (cattle, sheep, goats, buffaloes, pigs and others) or wild game animals to humans by direct contact or indirect contact with animals or their products. The incubation period typically ranges from 1 to 7 days, but may be longer (up to two to three weeks for cutaneous anthrax and up to 42 days for inhalation anthrax). Persons exposed to occupational hazards include those handling infected carcasses and those employed in the processing of bones, hides, wool and other animal products. Persons may also become infected by handling or consuming meat from animals that are sick with or have died of the disease. Biting flies have been reported to transmit the disease from infected animals to humans however how readily or often this occurs is unknown. Human anthrax is a serious problem in several countries and has potential for explosive outbreaks (especially the gastrointestinal form that is contracted from eating infected meat); while pulmonary (inhalation) anthrax is mainly occupational, the threat of biological warfare attacks should not be forgotten. Anthrax has a serious impact on the trade of animal products. The control of anthrax is based on its prevention in livestock. Programmes based only on prevention in humans are costly and likely to be ineffective except for those industrially exposed. There is an effective vaccine for those persons considered at risk for occupational exposure, and successful vaccines are used for livestock, particularly for herds with ongoing exposure to contaminated soil or vegetation. In most countries anthrax is a notifiable disease."}, {"prompt": "What does Anthrax (human) refer to? related to Yellow Fever Disease", "completion": "Anthrax is a widespread zoonotic disease caused by the spore-forming bacterium Bacillus anthracis, a Gram positive rod-shaped bacterium. A. It is transmitted from infected domestic livestock (cattle, sheep, goats, buffaloes, pigs and others) or wild game animals to humans by direct contact or indirect contact with animals or their products. The incubation period typically ranges from 1 to 7 days, but may be longer (up to two to three weeks for cutaneous anthrax and up to 42 days for inhalation anthrax). Persons exposed to occupational hazards include those handling infected carcasses and those employed in the processing of bones, hides, wool and other animal products. Persons may also become infected by handling or consuming meat from animals that are sick with or have died of the disease. Biting flies have been reported to transmit the disease from infected animals to humans however how readily or often this occurs is unknown. Human anthrax is a serious problem in several countries and has potential for explosive outbreaks (especially the gastrointestinal form that is contracted from eating infected meat); while pulmonary (inhalation) anthrax is mainly occupational, the threat of biological warfare attacks should not be forgotten. Anthrax has a serious impact on the trade of animal products. The control of anthrax is based on its prevention in livestock. Programmes based only on prevention in humans are costly and likely to be ineffective except for those industrially exposed. There is an effective vaccine for those persons considered at risk for occupational exposure, and successful vaccines are used for livestock, particularly for herds with ongoing exposure to contaminated soil or vegetation. In most countries anthrax is a notifiable disease."}, {"prompt": "What is the main goal of Anthrax (human) surveillance? related to Yellow Fever Disease", "completion": "To detect outbreaks. To monitor control and prevention programmes"}, {"prompt": "What is the primary objective of Anthrax (human) surveillance? related to Yellow Fever Disease", "completion": "To detect outbreaks. To monitor control and prevention programmes"}, {"prompt": "What is the central aim of Anthrax (human) surveillance? related to Yellow Fever Disease", "completion": "To detect outbreaks. To monitor control and prevention programmes"}, {"prompt": "What is the standard case definition for a suspected Anthrax (human) case? related to Yellow Fever Disease", "completion": "Any person with acute onset characterized by several clinical forms which are: Cutaneous form: Any person with skin lesion evolving over 1 to 6 days from a papular through a vesicular stage, to a depressed black eschar invariably accompanied by edema that may be mild to extensive. Castro-intestinal: Any person with abdominal distress characterized by nausea, vomiting, anorexia and followed by fever. Pulmonary (inhalation): any person with brief prodrome resembling acute viral respiratory illness, followed by rapid onset of hypoxia, dyspnoea and high temperature, with X-ray evidence of mediastinal widening. Meningeal: Any person with acute onset of high fever possibly with convulsions, loss of consciousness, meningeal signs and symptoms; commonly noted in all systemic infections, but may present without any other clinical symptoms of anthrax. AND has an epidemiological link to confirmed or suspected animal cases or contaminated animal products"}, {"prompt": "What criteria are used to identify a suspected Anthrax (human) case? related to Yellow Fever Disease", "completion": "Any person with acute onset characterized by several clinical forms which are: Cutaneous form: Any person with skin lesion evolving over 1 to 6 days from a papular through a vesicular stage, to a depressed black eschar invariably accompanied by edema that may be mild to extensive. Castro-intestinal: Any person with abdominal distress characterized by nausea, vomiting, anorexia and followed by fever. Pulmonary (inhalation): any person with brief prodrome resembling acute viral respiratory illness, followed by rapid onset of hypoxia, dyspnoea and high temperature, with X-ray evidence of mediastinal widening. Meningeal: Any person with acute onset of high fever possibly with convulsions, loss of consciousness, meningeal signs and symptoms; commonly noted in all systemic infections, but may present without any other clinical symptoms of anthrax. AND has an epidemiological link to confirmed or suspected animal cases or contaminated animal products"}, {"prompt": "How is a suspected Anthrax (human) case defined? related to Yellow Fever Disease", "completion": "Any person with acute onset characterized by several clinical forms which are: Cutaneous form: Any person with skin lesion evolving over 1 to 6 days from a papular through a vesicular stage, to a depressed black eschar invariably accompanied by edema that may be mild to extensive. Castro-intestinal: Any person with abdominal distress characterized by nausea, vomiting, anorexia and followed by fever. Pulmonary (inhalation): any person with brief prodrome resembling acute viral respiratory illness, followed by rapid onset of hypoxia, dyspnoea and high temperature, with X-ray evidence of mediastinal widening. Meningeal: Any person with acute onset of high fever possibly with convulsions, loss of consciousness, meningeal signs and symptoms; commonly noted in all systemic infections, but may present without any other clinical symptoms of anthrax. AND has an epidemiological link to confirmed or suspected animal cases or contaminated animal products"}, {"prompt": "How is a confirmed case of Anthrax (human) defined? related to Yellow Fever Disease", "completion": "A confirmed case of anthrax in a human can be defined as a clinically compatible case of cutaneous, inhalational or gastrointestinal illness that is laboratory-confirmed by: isolation of B. anthracis from an affected tissue or site; or Other laboratory evidence of B. anthracis infection based on at least two supportive laboratory tests. Note: it may not be possible to demonstrate B. anthracis in clinical specimens if the patient has been treated with antimicrobial agents."}, {"prompt": "What are the criteria for confirming an Anthrax (human) case? related to Yellow Fever Disease", "completion": "A confirmed case of anthrax in a human can be defined as a clinically compatible case of cutaneous, inhalational or gastrointestinal illness that is laboratory-confirmed by: isolation of B. anthracis from an affected tissue or site; or Other laboratory evidence of B. anthracis infection based on at least two supportive laboratory tests. Note: it may not be possible to demonstrate B. anthracis in clinical specimens if the patient has been treated with antimicrobial agents."}, {"prompt": "How to respond if Anthrax (human) cases are suspected and an alert threshold is reached? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels (public health sector and animal health sector). Use standard barrier precautions for all forms. Use protective equipment and clothing (gloves, gowns, face shields), and respiratory protection if there is a risk of aerosols, disinfection and dressing any cuts and abrasion before putting on protective clothing. Perform environmental cleaning (disinfection) with hypochlorite. Treat and manage the patient with supportive care and using antibiotics such as Penicillin V, procaine penicillin (uncomplicated cases), or penicillin G (severe cases). Collect specimen safely to confirm the case. Conduct joint (public health and animal health sectors) investigation of cases/deaths. Vaccination is required for animals when exported/imported. In humans, selective preventive vaccination may be considered in case of occupational exposure"}, {"prompt": "What actions should be taken if Anthrax (human) cases are suspected and an alert threshold is met? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels (public health sector and animal health sector). Use standard barrier precautions for all forms. Use protective equipment and clothing (gloves, gowns, face shields), and respiratory protection if there is a risk of aerosols, disinfection and dressing any cuts and abrasion before putting on protective clothing. Perform environmental cleaning (disinfection) with hypochlorite. Treat and manage the patient with supportive care and using antibiotics such as Penicillin V, procaine penicillin (uncomplicated cases), or penicillin G (severe cases). Collect specimen safely to confirm the case. Conduct joint (public health and animal health sectors) investigation of cases/deaths. Vaccination is required for animals when exported/imported. In humans, selective preventive vaccination may be considered in case of occupational exposure"}, {"prompt": "What are the steps to take if Anthrax (human) cases are suspected and an alert threshold is reached? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels (public health sector and animal health sector). Use standard barrier precautions for all forms. Use protective equipment and clothing (gloves, gowns, face shields), and respiratory protection if there is a risk of aerosols, disinfection and dressing any cuts and abrasion before putting on protective clothing. Perform environmental cleaning (disinfection) with hypochlorite. Treat and manage the patient with supportive care and using antibiotics such as Penicillin V, procaine penicillin (uncomplicated cases), or penicillin G (severe cases). Collect specimen safely to confirm the case. Conduct joint (public health and animal health sectors) investigation of cases/deaths. Vaccination is required for animals when exported/imported. In humans, selective preventive vaccination may be considered in case of occupational exposure"}, {"prompt": "What should be done if Anthrax (human) cases are suspected and an alert threshold is met? related to Yellow Fever Disease", "completion": "If a single case is suspected: Report case-based information immediately to the appropriate levels (public health sector and animal health sector). Use standard barrier precautions for all forms. Use protective equipment and clothing (gloves, gowns, face shields), and respiratory protection if there is a risk of aerosols, disinfection and dressing any cuts and abrasion before putting on protective clothing. Perform environmental cleaning (disinfection) with hypochlorite. Treat and manage the patient with supportive care and using antibiotics such as Penicillin V, procaine penicillin (uncomplicated cases), or penicillin G (severe cases). Collect specimen safely to confirm the case. Conduct joint (public health and animal health sectors) investigation of cases/deaths. Vaccination is required for animals when exported/imported. In humans, selective preventive vaccination may be considered in case of occupational exposure"}, {"prompt": "What actions should be taken if Anthrax (human) cases are confirmed and an action threshold is reached? related to Yellow Fever Disease", "completion": "If a single case is confirmed: Standard infection control precautions are sufficient and should be used when managing patients. Particular attention should be paid to body fluid spills which should be managed by the usual methods for cleaning and decontamination of anybody fluid spills. This should be done promptly and thoroughly, because organisms which remain on surfaces may form spores which are infectious. As is usual practice, personal protective equipment should be used in situations where there is potential for splashes and inoculation injuries. Any incidents should be reported immediately. Mobilize the community for early detection and care. Proper burial or cremation (if practiced) of dead bodies (humans and animals). Conduct community education about the confirmed case, how the disease is transmitted, and how to use infection control in the home care setting. Conduct active searches for additional cases that may not come to the health care setting (older women or small children, for example) and provide information about prevention in the home and when to seek care. Request additional help from national levels as needed."}, {"prompt": "What measures should be taken if Anthrax (human) cases are confirmed and an action threshold is met? related to Yellow Fever Disease", "completion": "If a single case is confirmed: Standard infection control precautions are sufficient and should be used when managing patients. Particular attention should be paid to body fluid spills which should be managed by the usual methods for cleaning and decontamination of anybody fluid spills. This should be done promptly and thoroughly, because organisms which remain on surfaces may form spores which are infectious. As is usual practice, personal protective equipment should be used in situations where there is potential for splashes and inoculation injuries. Any incidents should be reported immediately. Mobilize the community for early detection and care. Proper burial or cremation (if practiced) of dead bodies (humans and animals). Conduct community education about the confirmed case, how the disease is transmitted, and how to use infection control in the home care setting. Conduct active searches for additional cases that may not come to the health care setting (older women or small children, for example) and provide information about prevention in the home and when to seek care. Request additional help from national levels as needed."}, {"prompt": "What steps should be taken if Anthrax (human) cases are confirmed and an action threshold is reached? related to Yellow Fever Disease", "completion": "If a single case is confirmed: Standard infection control precautions are sufficient and should be used when managing patients. Particular attention should be paid to body fluid spills which should be managed by the usual methods for cleaning and decontamination of anybody fluid spills. This should be done promptly and thoroughly, because organisms which remain on surfaces may form spores which are infectious. As is usual practice, personal protective equipment should be used in situations where there is potential for splashes and inoculation injuries. Any incidents should be reported immediately. Mobilize the community for early detection and care. Proper burial or cremation (if practiced) of dead bodies (humans and animals). Conduct community education about the confirmed case, how the disease is transmitted, and how to use infection control in the home care setting. Conduct active searches for additional cases that may not come to the health care setting (older women or small children, for example) and provide information about prevention in the home and when to seek care. Request additional help from national levels as needed."}, {"prompt": "What measures should be taken if Anthrax (human) cases are confirmed and an action threshold is met? related to Yellow Fever Disease", "completion": "If a single case is confirmed: Standard infection control precautions are sufficient and should be used when managing patients. Particular attention should be paid to body fluid spills which should be managed by the usual methods for cleaning and decontamination of anybody fluid spills. This should be done promptly and thoroughly, because organisms which remain on surfaces may form spores which are infectious. As is usual practice, personal protective equipment should be used in situations where there is potential for splashes and inoculation injuries. Any incidents should be reported immediately. Mobilize the community for early detection and care. Proper burial or cremation (if practiced) of dead bodies (humans and animals). Conduct community education about the confirmed case, how the disease is transmitted, and how to use infection control in the home care setting. Conduct active searches for additional cases that may not come to the health care setting (older women or small children, for example) and provide information about prevention in the home and when to seek care. Request additional help from national levels as needed."}, {"prompt": "How should data about a person with Anthrax (human) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Table showing the number of suspected / probable / confirmed cases by date, age and sex"}, {"prompt": "What is the appropriate method to analyze and interpret data about a person with Anthrax (human)? related to Yellow Fever Disease", "completion": "Table showing the number of suspected / probable / confirmed cases by date, age and sex"}, {"prompt": "How to analyze and interpret data about time in the context of Anthrax (human)? related to Yellow Fever Disease", "completion": "Graphs of number of suspected / probable / confirmed cases by date."}, {"prompt": "What is the recommended way to analyze and interpret data about time in the context of Anthrax (human)? related to Yellow Fever Disease", "completion": "Graphs of number of suspected / probable / confirmed cases by date."}, {"prompt": "How should data about place in the context of Anthrax (human) be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Map of suspected and confirmed human and animal cases by geographical area (district)"}, {"prompt": "What is the suitable method to analyze and interpret data about place in the context of Anthrax (human)? related to Yellow Fever Disease", "completion": "Map of suspected and confirmed human and animal cases by geographical area (district)"}, {"prompt": "What are the references for Anthrax (human)? related to Yellow Fever Disease", "completion": "1. WHO. Anthrax in humans and animals. World Health Organization, Geneva. (2008) (Available on http://www.who.int/csr/resources/publications/ AnthraxGuidelines2008/en/index.html)\n2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n3. WHO recommended Strategies for the Prevention and Control of Communicable Diseases, WHO/CDS/CPE/SMT/2001.13\n4. 2003 WHO Manual for Laboratory Diagnosis of Anthrax (http://www.searo.who.int/en/Section10/Section17/ Section58/Section909.htm)\n5. CDC: Anthrax Information for Health Care Providers\" (http://emergency.cdc.gov/agent/anthrax/anthrax-hcp- factsheet.asp)\n6. CDC: Recommended Specimens for Microbiology and Pathology for Diagnosis:"}, {"prompt": "What are the sources of information for Anthrax (human)? related to Yellow Fever Disease", "completion": "1. WHO. Anthrax in humans and animals. World Health Organization, Geneva. (2008) (Available on http://www.who.int/csr/resources/publications/ AnthraxGuidelines2008/en/index.html)\n2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n3. WHO recommended Strategies for the Prevention and Control of Communicable Diseases, WHO/CDS/CPE/SMT/2001.13\n4. 2003 WHO Manual for Laboratory Diagnosis of Anthrax (http://www.searo.who.int/en/Section10/Section17/ Section58/Section909.htm)\n5. CDC: Anthrax Information for Health Care Providers\" (http://emergency.cdc.gov/agent/anthrax/anthrax-hcp- factsheet.asp)\n6. CDC: Recommended Specimens for Microbiology and Pathology for Diagnosis:"}, {"prompt": "What are the references used for Anthrax (human)? related to Yellow Fever Disease", "completion": "1. WHO. Anthrax in humans and animals. World Health Organization, Geneva. (2008) (Available on http://www.who.int/csr/resources/publications/ AnthraxGuidelines2008/en/index.html)\n2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2\n3. WHO recommended Strategies for the Prevention and Control of Communicable Diseases, WHO/CDS/CPE/SMT/2001.13\n4. 2003 WHO Manual for Laboratory Diagnosis of Anthrax (http://www.searo.who.int/en/Section10/Section17/ Section58/Section909.htm)\n5. CDC: Anthrax Information for Health Care Providers\" (http://emergency.cdc.gov/agent/anthrax/anthrax-hcp- factsheet.asp)\n6. CDC: Recommended Specimens for Microbiology and Pathology for Diagnosis:"}, {"prompt": "Explain Adverse Events Following Immunization (AEFI). related to Yellow Fever Disease", "completion": "Reports of AEFIs have had negative effects on national immunization programmes. Most reports are coincidental events not related to vaccines. It is important to identify real events and determine their cause."}, {"prompt": "Define Adverse Events Following Immunization (AEFI). related to Yellow Fever Disease", "completion": "Reports of AEFIs have had negative effects on national immunization programmes. Most reports are coincidental events not related to vaccines. It is important to identify real events and determine their cause."}, {"prompt": "Elaborate on Adverse Events Following Immunization (AEFI). related to Yellow Fever Disease", "completion": "Reports of AEFIs have had negative effects on national immunization programmes. Most reports are coincidental events not related to vaccines. It is important to identify real events and determine their cause."}, {"prompt": "Describe Adverse Events Following Immunization (AEFI). related to Yellow Fever Disease", "completion": "Reports of AEFIs have had negative effects on national immunization programmes. Most reports are coincidental events not related to vaccines. It is important to identify real events and determine their cause."}, {"prompt": "What are Adverse Events Following Immunization (AEFI)? related to Yellow Fever Disease", "completion": "Reports of AEFIs have had negative effects on national immunization programmes. Most reports are coincidental events not related to vaccines. It is important to identify real events and determine their cause."}, {"prompt": "What is the objective of AEFI surveillance? related to Yellow Fever Disease", "completion": "To determine the cause of an AEFI or cluster of AEFIs and correct it."}, {"prompt": "What is the purpose of monitoring Adverse Events Following Immunization (AEFI)? related to Yellow Fever Disease", "completion": "To determine the cause of an AEFI or cluster of AEFIs and correct it."}, {"prompt": "What are the goals of AEFI surveillance? related to Yellow Fever Disease", "completion": "To determine the cause of an AEFI or cluster of AEFIs and correct it."}, {"prompt": "What is the standard case definition for AEFI? related to Yellow Fever Disease", "completion": "A medical incident that takes place after immunization, causes concern and is believed to be caused by the immunization."}, {"prompt": "How is AEFI defined? related to Yellow Fever Disease", "completion": "A medical incident that takes place after immunization, causes concern and is believed to be caused by the immunization."}, {"prompt": "What is the criteria for suspecting AEFI? related to Yellow Fever Disease", "completion": "A medical incident that takes place after immunization, causes concern and is believed to be caused by the immunization."}, {"prompt": "How should the alert threshold for AEFI be managed if cases are suspected? related to Yellow Fever Disease", "completion": "If a single case is suspected: Treat the patient. Communicate with the parents and community. Respond to rumours or public enquiries. Complete case investigation form."}, {"prompt": "What actions should be taken when AEFI cases are suspected and the alert threshold is reached? related to Yellow Fever Disease", "completion": "If a single case is suspected: Treat the patient. Communicate with the parents and community. Respond to rumours or public enquiries. Complete case investigation form."}, {"prompt": "How should the action threshold for AEFI be handled if cases are confirmed? related to Yellow Fever Disease", "completion": "If a single case is confirmed: Monitor for a cluster. Send report immediately to initiate investigation of cause. Take remedial action to avoid another AEFI occurring from the same cause."}, {"prompt": "What steps should be taken when AEFI cases are confirmed and the action threshold is reached? related to Yellow Fever Disease", "completion": "If a single case is confirmed: Monitor for a cluster. Send report immediately to initiate investigation of cause. Take remedial action to avoid another AEFI occurring from the same cause."}, {"prompt": "How should data about AEFI be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Determine the cause of the event. Is it programme-related, Vaccine-induced, coincidental or unknown? Beware of mass psychological illness if a number of school-aged or older individuals are involved at the same time."}, {"prompt": "What methods are used for data analysis of AEFI? related to Yellow Fever Disease", "completion": "Determine the cause of the event. Is it programme-related, Vaccine-induced, coincidental or unknown? Beware of mass psychological illness if a number of school-aged or older individuals are involved at the same time."}, {"prompt": "How can data about AEFI be interpreted and analyzed? related to Yellow Fever Disease", "completion": "Determine the cause of the event. Is it programme-related, Vaccine-induced, coincidental or unknown? Beware of mass psychological illness if a number of school-aged or older individuals are involved at the same time."}, {"prompt": "What are the resources for Adverse Events Following Immunization (AEFI)? related to Yellow Fever Disease", "completion": "1. Surveillance of adverse events following immunization. Field guide for managers of immunization programmes. WHO/EPI/93.02 Rev 1. http://www.who.int/vaccines- documents/DocsPDF/www9541.pdf\n2. Kharabsheh S. Mass psychogenic illness following Td vaccine in Jordan. Bulletin of the WHO 2001. 79 (8); 764-770. http://www.who.int/bulletin/pdf/2001/issue8/vol79.no.8.764- 770.pdf"}, {"prompt": "Where can I find more information about AEFI? related to Yellow Fever Disease", "completion": "1. Surveillance of adverse events following immunization. Field guide for managers of immunization programmes. WHO/EPI/93.02 Rev 1. http://www.who.int/vaccines- documents/DocsPDF/www9541.pdf\n2. Kharabsheh S. Mass psychogenic illness following Td vaccine in Jordan. Bulletin of the WHO 2001. 79 (8); 764-770. http://www.who.int/bulletin/pdf/2001/issue8/vol79.no.8.764- 770.pdf"}, {"prompt": "Define Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Viral hepatitis A and viral hepatitis E: Enterically transmitted HAV and HEV are a worldwide problem. Common source epidemics have been related to contaminated water and to contamination via infected food handlers. In general, both HAV and HEV are self-limiting viral infections; case fatality is normally low (0.1 _ 0.3%). Women in the third trimester of pregnancy are especially susceptible to fulminant HEV disease. Both HAV and HEV are transmitted via the faecal-oral route. Prevention and control measures for hepatitis A and hepatitis E include adequate supplies of safe-drinking water and improvement of sanitary and hygienic practices to eliminate faecal contamination of food and water. Viral hepatitis B and viral hepatitis C: Estimates indicate that worldwide, there are 350 million carriers of hepatitis B virus and 170 million carriers of hepatitis C virus. Hepatitis B and C epidemics are uncommon. Chronic infection and severe sequelae occur with hepatitis B_ an estimated 15% to 25% of chronically infected persons will die prematurely of either cirrhosis or hepatocellular carcinoma. Chronic infection is common in hepatitis C and 5% to 20% of those infected with HCV may develop cirrhosis. There seems to be a connection between HCV infection and hepatocellular carcinoma. Hepatitis B is transmitted by percutaneous or permucosal exposure to blood or other infectious body fluids. Major modes of transmission include sexual contact with an infected person, perinatal transmission from mother to infant, shared needles or syringes among injecting drug users, household contact (e.g., communally used razors and toothbrushes) and nosocomial exposure (transfusions, unsafe injection practices). In most countries where HBV is highly endemic, most infections occur during infancy and early childhood. Hepatitis C is transmitted by parenteral exposure to blood and plasma derivatives. It is found in highest concentrations in blood. The major causes of HCV infection worldwide are use of unscreened blood transfusions and re-use of needles and syringes that have not been adequately sterilised. Prevention and control measures for hepatitis B and C include transfusion safety, safe and appropriate use of injections and vaccination (hepatitis B). There is no specific treatment for acute viral hepatitis A, B, C and D."}, {"prompt": "Describe Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Viral hepatitis A and viral hepatitis E: Enterically transmitted HAV and HEV are a worldwide problem. Common source epidemics have been related to contaminated water and to contamination via infected food handlers. In general, both HAV and HEV are self-limiting viral infections; case fatality is normally low (0.1 _ 0.3%). Women in the third trimester of pregnancy are especially susceptible to fulminant HEV disease. Both HAV and HEV are transmitted via the faecal-oral route. Prevention and control measures for hepatitis A and hepatitis E include adequate supplies of safe-drinking water and improvement of sanitary and hygienic practices to eliminate faecal contamination of food and water. Viral hepatitis B and viral hepatitis C: Estimates indicate that worldwide, there are 350 million carriers of hepatitis B virus and 170 million carriers of hepatitis C virus. Hepatitis B and C epidemics are uncommon. Chronic infection and severe sequelae occur with hepatitis B_ an estimated 15% to 25% of chronically infected persons will die prematurely of either cirrhosis or hepatocellular carcinoma. Chronic infection is common in hepatitis C and 5% to 20% of those infected with HCV may develop cirrhosis. There seems to be a connection between HCV infection and hepatocellular carcinoma. Hepatitis B is transmitted by percutaneous or permucosal exposure to blood or other infectious body fluids. Major modes of transmission include sexual contact with an infected person, perinatal transmission from mother to infant, shared needles or syringes among injecting drug users, household contact (e.g., communally used razors and toothbrushes) and nosocomial exposure (transfusions, unsafe injection practices). In most countries where HBV is highly endemic, most infections occur during infancy and early childhood. Hepatitis C is transmitted by parenteral exposure to blood and plasma derivatives. It is found in highest concentrations in blood. The major causes of HCV infection worldwide are use of unscreened blood transfusions and re-use of needles and syringes that have not been adequately sterilised. Prevention and control measures for hepatitis B and C include transfusion safety, safe and appropriate use of injections and vaccination (hepatitis B). There is no specific treatment for acute viral hepatitis A, B, C and D."}, {"prompt": "Elaborate on Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Viral hepatitis A and viral hepatitis E: Enterically transmitted HAV and HEV are a worldwide problem. Common source epidemics have been related to contaminated water and to contamination via infected food handlers. In general, both HAV and HEV are self-limiting viral infections; case fatality is normally low (0.1 _ 0.3%). Women in the third trimester of pregnancy are especially susceptible to fulminant HEV disease. Both HAV and HEV are transmitted via the faecal-oral route. Prevention and control measures for hepatitis A and hepatitis E include adequate supplies of safe-drinking water and improvement of sanitary and hygienic practices to eliminate faecal contamination of food and water. Viral hepatitis B and viral hepatitis C: Estimates indicate that worldwide, there are 350 million carriers of hepatitis B virus and 170 million carriers of hepatitis C virus. Hepatitis B and C epidemics are uncommon. Chronic infection and severe sequelae occur with hepatitis B_ an estimated 15% to 25% of chronically infected persons will die prematurely of either cirrhosis or hepatocellular carcinoma. Chronic infection is common in hepatitis C and 5% to 20% of those infected with HCV may develop cirrhosis. There seems to be a connection between HCV infection and hepatocellular carcinoma. Hepatitis B is transmitted by percutaneous or permucosal exposure to blood or other infectious body fluids. Major modes of transmission include sexual contact with an infected person, perinatal transmission from mother to infant, shared needles or syringes among injecting drug users, household contact (e.g., communally used razors and toothbrushes) and nosocomial exposure (transfusions, unsafe injection practices). In most countries where HBV is highly endemic, most infections occur during infancy and early childhood. Hepatitis C is transmitted by parenteral exposure to blood and plasma derivatives. It is found in highest concentrations in blood. The major causes of HCV infection worldwide are use of unscreened blood transfusions and re-use of needles and syringes that have not been adequately sterilised. Prevention and control measures for hepatitis B and C include transfusion safety, safe and appropriate use of injections and vaccination (hepatitis B). There is no specific treatment for acute viral hepatitis A, B, C and D."}, {"prompt": "Provide a summary of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Viral hepatitis A and viral hepatitis E: Enterically transmitted HAV and HEV are a worldwide problem. Common source epidemics have been related to contaminated water and to contamination via infected food handlers. In general, both HAV and HEV are self-limiting viral infections; case fatality is normally low (0.1 _ 0.3%). Women in the third trimester of pregnancy are especially susceptible to fulminant HEV disease. Both HAV and HEV are transmitted via the faecal-oral route. Prevention and control measures for hepatitis A and hepatitis E include adequate supplies of safe-drinking water and improvement of sanitary and hygienic practices to eliminate faecal contamination of food and water. Viral hepatitis B and viral hepatitis C: Estimates indicate that worldwide, there are 350 million carriers of hepatitis B virus and 170 million carriers of hepatitis C virus. Hepatitis B and C epidemics are uncommon. Chronic infection and severe sequelae occur with hepatitis B_ an estimated 15% to 25% of chronically infected persons will die prematurely of either cirrhosis or hepatocellular carcinoma. Chronic infection is common in hepatitis C and 5% to 20% of those infected with HCV may develop cirrhosis. There seems to be a connection between HCV infection and hepatocellular carcinoma. Hepatitis B is transmitted by percutaneous or permucosal exposure to blood or other infectious body fluids. Major modes of transmission include sexual contact with an infected person, perinatal transmission from mother to infant, shared needles or syringes among injecting drug users, household contact (e.g., communally used razors and toothbrushes) and nosocomial exposure (transfusions, unsafe injection practices). In most countries where HBV is highly endemic, most infections occur during infancy and early childhood. Hepatitis C is transmitted by parenteral exposure to blood and plasma derivatives. It is found in highest concentrations in blood. The major causes of HCV infection worldwide are use of unscreened blood transfusions and re-use of needles and syringes that have not been adequately sterilised. Prevention and control measures for hepatitis B and C include transfusion safety, safe and appropriate use of injections and vaccination (hepatitis B). There is no specific treatment for acute viral hepatitis A, B, C and D."}, {"prompt": "Explain Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Viral hepatitis A and viral hepatitis E: Enterically transmitted HAV and HEV are a worldwide problem. Common source epidemics have been related to contaminated water and to contamination via infected food handlers. In general, both HAV and HEV are self-limiting viral infections; case fatality is normally low (0.1 _ 0.3%). Women in the third trimester of pregnancy are especially susceptible to fulminant HEV disease. Both HAV and HEV are transmitted via the faecal-oral route. Prevention and control measures for hepatitis A and hepatitis E include adequate supplies of safe-drinking water and improvement of sanitary and hygienic practices to eliminate faecal contamination of food and water. Viral hepatitis B and viral hepatitis C: Estimates indicate that worldwide, there are 350 million carriers of hepatitis B virus and 170 million carriers of hepatitis C virus. Hepatitis B and C epidemics are uncommon. Chronic infection and severe sequelae occur with hepatitis B_ an estimated 15% to 25% of chronically infected persons will die prematurely of either cirrhosis or hepatocellular carcinoma. Chronic infection is common in hepatitis C and 5% to 20% of those infected with HCV may develop cirrhosis. There seems to be a connection between HCV infection and hepatocellular carcinoma. Hepatitis B is transmitted by percutaneous or permucosal exposure to blood or other infectious body fluids. Major modes of transmission include sexual contact with an infected person, perinatal transmission from mother to infant, shared needles or syringes among injecting drug users, household contact (e.g., communally used razors and toothbrushes) and nosocomial exposure (transfusions, unsafe injection practices). In most countries where HBV is highly endemic, most infections occur during infancy and early childhood. Hepatitis C is transmitted by parenteral exposure to blood and plasma derivatives. It is found in highest concentrations in blood. The major causes of HCV infection worldwide are use of unscreened blood transfusions and re-use of needles and syringes that have not been adequately sterilised. Prevention and control measures for hepatitis B and C include transfusion safety, safe and appropriate use of injections and vaccination (hepatitis B). There is no specific treatment for acute viral hepatitis A, B, C and D."}, {"prompt": "What is the goal of surveillance for Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Detect hepatitis outbreaks. Identify areas/populations at high risk to target prevention and control measures. Estimate burden of disease. If countrywide surveillance is not possible, surveillance in sentinel areas or hospitals may provide useful information on potential sources of infection."}, {"prompt": "What is the purpose of surveillance for Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Detect hepatitis outbreaks. Identify areas/populations at high risk to target prevention and control measures. Estimate burden of disease. If countrywide surveillance is not possible, surveillance in sentinel areas or hospitals may provide useful information on potential sources of infection."}, {"prompt": "Explain the surveillance goal for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Detect hepatitis outbreaks. Identify areas/populations at high risk to target prevention and control measures. Estimate burden of disease. If countrywide surveillance is not possible, surveillance in sentinel areas or hospitals may provide useful information on potential sources of infection."}, {"prompt": "Describe the surveillance goal for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Detect hepatitis outbreaks. Identify areas/populations at high risk to target prevention and control measures. Estimate burden of disease. If countrywide surveillance is not possible, surveillance in sentinel areas or hospitals may provide useful information on potential sources of infection."}, {"prompt": "What is the standard case definition for a suspected case of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Any person with acute illness typically including acute jaundice, dark urine, anorexia, malaise, extreme fatigue, and right upper quadrant tenderness. (Note: infected children are often asymptomatic.)"}, {"prompt": "Define the standard case definition for a suspected case of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Any person with acute illness typically including acute jaundice, dark urine, anorexia, malaise, extreme fatigue, and right upper quadrant tenderness. (Note: infected children are often asymptomatic.)"}, {"prompt": "Explain the standard case definition for a suspected case of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Any person with acute illness typically including acute jaundice, dark urine, anorexia, malaise, extreme fatigue, and right upper quadrant tenderness. (Note: infected children are often asymptomatic.)"}, {"prompt": "What is the standard definition for a suspected case of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Any person with acute illness typically including acute jaundice, dark urine, anorexia, malaise, extreme fatigue, and right upper quadrant tenderness. (Note: infected children are often asymptomatic.)"}, {"prompt": "What is the standard case definition for a confirmed case of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed"}, {"prompt": "Explain the standard case definition for a confirmed case of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed"}, {"prompt": "Define the standard case definition for a confirmed case of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed"}, {"prompt": "Describe the standard case definition for a confirmed case of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "A suspected case that is laboratory confirmed"}, {"prompt": "How should an alert threshold response be handled if hepatitis cases are suspected? related to Yellow Fever Disease", "completion": "Report case-based information to the appropriate levels. As necessary, treat and manage the patient(s) with supportive care. Collect specimens and send to the laboratory to identify the etiology of the illness."}, {"prompt": "What actions should be taken if there's an alert threshold response and hepatitis cases are suspected? related to Yellow Fever Disease", "completion": "Report case-based information to the appropriate levels. As necessary, treat and manage the patient(s) with supportive care. Collect specimens and send to the laboratory to identify the etiology of the illness."}, {"prompt": "Explain the response to an alert threshold if hepatitis cases are suspected. related to Yellow Fever Disease", "completion": "Report case-based information to the appropriate levels. As necessary, treat and manage the patient(s) with supportive care. Collect specimens and send to the laboratory to identify the etiology of the illness."}, {"prompt": "How to respond if an alert threshold is reached and hepatitis cases are suspected? related to Yellow Fever Disease", "completion": "Report case-based information to the appropriate levels. As necessary, treat and manage the patient(s) with supportive care. Collect specimens and send to the laboratory to identify the etiology of the illness."}, {"prompt": "What actions should be taken if there's an action threshold response and hepatitis cases are confirmed? related to Yellow Fever Disease", "completion": "Determine the mode of transmission. Identify the population exposed to the risk of infection. Eliminate common sources of infection. Implement appropriate prevention and control interventions."}, {"prompt": "How to respond to an action threshold if hepatitis cases are confirmed? related to Yellow Fever Disease", "completion": "Determine the mode of transmission. Identify the population exposed to the risk of infection. Eliminate common sources of infection. Implement appropriate prevention and control interventions."}, {"prompt": "Explain the response to an action threshold if hepatitis cases are confirmed. related to Yellow Fever Disease", "completion": "Determine the mode of transmission. Identify the population exposed to the risk of infection. Eliminate common sources of infection. Implement appropriate prevention and control interventions."}, {"prompt": "What should be done if there's an action threshold response and hepatitis cases are confirmed? related to Yellow Fever Disease", "completion": "Determine the mode of transmission. Identify the population exposed to the risk of infection. Eliminate common sources of infection. Implement appropriate prevention and control interventions."}, {"prompt": "How to analyze and interpret data about a person with Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Analyze by age and gender. Assess risk factors to plan and monitor prevention and control measures."}, {"prompt": "Explain how to analyze and interpret data about a person with Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Analyze by age and gender. Assess risk factors to plan and monitor prevention and control measures."}, {"prompt": "What is the process of analyzing and interpreting data about a person with Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Analyze by age and gender. Assess risk factors to plan and monitor prevention and control measures."}, {"prompt": "How to interpret and analyze data about a person with Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Analyze by age and gender. Assess risk factors to plan and monitor prevention and control measures."}, {"prompt": "How to analyze and interpret data about time in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Analyze suspected and confirmed cases by week. Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "Explain how to analyze and interpret data about time in the context of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Analyze suspected and confirmed cases by week. Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "What is the process of analyzing and interpreting data about time in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Analyze suspected and confirmed cases by week. Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "How to interpret and analyze data about time in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Analyze suspected and confirmed cases by week. Graph cases and deaths weekly. Construct an epidemic curve during outbreaks."}, {"prompt": "How to analyze and interpret data about place in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "Explain how to analyze and interpret data about place in the context of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "What is the process of analyzing and interpreting data about place in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "How to interpret and analyze data about place in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Plot the location of case households."}, {"prompt": "What is the laboratory confirmation diagnostic test for Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Hepatitis A: IgM anti-HAV positive. Hepatitis B: +ve for Hepatitis B surface antigen (HbsAg) or IgM anti-HBc positive. Hepatitis C: Anti-HCV positive. Hepatitis D: HBsAg positive or IgM anti-HBc positive plus anti-HDV positive (only as co-infection or super-infection of hepatitis B). Hepatitis E: IgM anti-HEV positive and/or IgG anti-HEV positive"}, {"prompt": "Explain the laboratory confirmation diagnostic test for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Hepatitis A: IgM anti-HAV positive. Hepatitis B: +ve for Hepatitis B surface antigen (HbsAg) or IgM anti-HBc positive. Hepatitis C: Anti-HCV positive. Hepatitis D: HBsAg positive or IgM anti-HBc positive plus anti-HDV positive (only as co-infection or super-infection of hepatitis B). Hepatitis E: IgM anti-HEV positive and/or IgG anti-HEV positive"}, {"prompt": "Describe the laboratory confirmation diagnostic test for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Hepatitis A: IgM anti-HAV positive. Hepatitis B: +ve for Hepatitis B surface antigen (HbsAg) or IgM anti-HBc positive. Hepatitis C: Anti-HCV positive. Hepatitis D: HBsAg positive or IgM anti-HBc positive plus anti-HDV positive (only as co-infection or super-infection of hepatitis B). Hepatitis E: IgM anti-HEV positive and/or IgG anti-HEV positive"}, {"prompt": "What is the laboratory confirmation specimen type for Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Serum"}, {"prompt": "Explain the laboratory confirmation specimen type for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Serum"}, {"prompt": "Describe the laboratory confirmation specimen type for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Serum"}, {"prompt": "When to collect specimens for laboratory confirmation in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Specimens should be collected from a suspected patient. IgM anti-HAV becomes detectable 5-10 days after exposure. HBsAg can be detected in serum from several weeks before the onset of symptoms to days, weeks, or months after onset; it persists in chronic infections. IgM anti-HBc positive usually disappears within 6 months."}, {"prompt": "Explain when to collect specimens for laboratory confirmation in the context of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Specimens should be collected from a suspected patient. IgM anti-HAV becomes detectable 5-10 days after exposure. HBsAg can be detected in serum from several weeks before the onset of symptoms to days, weeks, or months after onset; it persists in chronic infections. IgM anti-HBc positive usually disappears within 6 months."}, {"prompt": "What is the process of collecting specimens for laboratory confirmation in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Specimens should be collected from a suspected patient. IgM anti-HAV becomes detectable 5-10 days after exposure. HBsAg can be detected in serum from several weeks before the onset of symptoms to days, weeks, or months after onset; it persists in chronic infections. IgM anti-HBc positive usually disappears within 6 months."}, {"prompt": "How to prepare, store, and transport specimens for laboratory confirmation in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Use universal precautions to minimize exposure to sharps and any body fluid. Collect 5-10 ml of venous blood. Let clot retract for 30 to 60 minutes at room temperature or centrifuge to separate serum from red blood cells. Aseptically pour off serum into sterile, screw-capped tubes. Store serum at 4\u00b0C. For storage >5 days, samples are held at -20\u00b0C. Transport serum samples using appropriate packaging to prevent breakage or leakage."}, {"prompt": "Explain how to prepare, store, and transport specimens for laboratory confirmation in the context of Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Use universal precautions to minimize exposure to sharps and any body fluid. Collect 5-10 ml of venous blood. Let clot retract for 30 to 60 minutes at room temperature or centrifuge to separate serum from red blood cells. Aseptically pour off serum into sterile, screw-capped tubes. Store serum at 4\u00b0C. For storage >5 days, samples are held at -20\u00b0C. Transport serum samples using appropriate packaging to prevent breakage or leakage."}, {"prompt": "What are the steps for preparing, storing, and transporting specimens for laboratory confirmation in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Use universal precautions to minimize exposure to sharps and any body fluid. Collect 5-10 ml of venous blood. Let clot retract for 30 to 60 minutes at room temperature or centrifuge to separate serum from red blood cells. Aseptically pour off serum into sterile, screw-capped tubes. Store serum at 4\u00b0C. For storage >5 days, samples are held at -20\u00b0C. Transport serum samples using appropriate packaging to prevent breakage or leakage."}, {"prompt": "How to properly handle, store, and transport specimens for laboratory confirmation in the context of Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Use universal precautions to minimize exposure to sharps and any body fluid. Collect 5-10 ml of venous blood. Let clot retract for 30 to 60 minutes at room temperature or centrifuge to separate serum from red blood cells. Aseptically pour off serum into sterile, screw-capped tubes. Store serum at 4\u00b0C. For storage >5 days, samples are held at -20\u00b0C. Transport serum samples using appropriate packaging to prevent breakage or leakage."}, {"prompt": "What are the results of laboratory confirmation for Acute viral hepatitis? related to Yellow Fever Disease", "completion": "Results are usually available within one to 3 days from arrival in the laboratory."}, {"prompt": "Explain the results of laboratory confirmation for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Results are usually available within one to 3 days from arrival in the laboratory."}, {"prompt": "Describe the results of laboratory confirmation for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "Results are usually available within one to 3 days from arrival in the laboratory."}, {"prompt": "What are the references for Acute viral hepatitis? related to Yellow Fever Disease", "completion": "1. WHO Recommended Strategies for Prevention and Control of Communicable Diseases; WHO/CDS/CPE/SMT/2001.13.\n2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2.\n3. WHO Fact Sheet No 328, Hepatitis A, revised May 2008.\n4. WHO Fact Sheet No 204, Hepatitis B, revised August 2008.\n5. WHO Fact Sheet No 164, Hepatitis C.\n6. WHO Fact Sheet No 280, Hepatitis E, revised January 2005.\n7. World Health Organization http://www.who.int/topics/hepatitis/en/\n8. United States, Centers for Disease Control and Prevention http://www.cdc.gov/hepatitis/\n9. Control of Communicable Diseases Manual, 18th Edition"}, {"prompt": "Provide the references for Acute viral hepatitis. related to Yellow Fever Disease", "completion": "1. WHO Recommended Strategies for Prevention and Control of Communicable Diseases; WHO/CDS/CPE/SMT/2001.13.\n2. WHO Recommended Surveillance Standards WHO/CDS/CSR/ISR/99.2.\n3. WHO Fact Sheet No 328, Hepatitis A, revised May 2008.\n4. WHO Fact Sheet No 204, Hepatitis B, revised August 2008.\n5. WHO Fact Sheet No 164, Hepatitis C.\n6. WHO Fact Sheet No 280, Hepatitis E, revised January 2005.\n7. World Health Organization http://www.who.int/topics/hepatitis/en/\n8. United States, Centers for Disease Control and Prevention http://www.cdc.gov/hepatitis/\n9. Control of Communicable Diseases Manual, 18th Edition"}, {"prompt": "Explain SARS-CoV-2 (COVID-19) virus. related to Yellow Fever Disease", "completion": "Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new virus that had not been previously identified in humans and therefore no population-level immunity exists. This virus belongs to the coronaviridae family grouped together in 1968 due to existence of crown-like appearances on their cell membrane. The virus is highly transmissible by way of inhalation of respiratory droplets, contact with contaminated objects and surfaces or occasionally by aerosol inhalation. It attacks the respiratory, intestinal and brain tissues."}, {"prompt": "What is the objective of surveillance for SARS-CoV-2? related to Yellow Fever Disease", "completion": "Early detection of COVID-19 cases and outbreaks, rapid investigation, and early laboratory verification of the cause of all suspected cases. Identify contacts and Investigate all suspected cases using a case definition according to the suspected, probable or confirmed disease should be used."}, {"prompt": "Define the surveillance goal for SARS-CoV-2. related to Yellow Fever Disease", "completion": "Early detection of COVID-19 cases and outbreaks, rapid investigation, and early laboratory verification of the cause of all suspected cases. Identify contacts and Investigate all suspected cases using a case definition according to the suspected, probable or confirmed disease should be used."}, {"prompt": "What is the primary aim of surveillance for SARS-CoV-2? related to Yellow Fever Disease", "completion": "Early detection of COVID-19 cases and outbreaks, rapid investigation, and early laboratory verification of the cause of all suspected cases. Identify contacts and Investigate all suspected cases using a case definition according to the suspected, probable or confirmed disease should be used."}, {"prompt": "Explain the surveillance objective for SARS-CoV-2. related to Yellow Fever Disease", "completion": "Early detection of COVID-19 cases and outbreaks, rapid investigation, and early laboratory verification of the cause of all suspected cases. Identify contacts and Investigate all suspected cases using a case definition according to the suspected, probable or confirmed disease should be used."}, {"prompt": "What is the case definition for a suspected sporadic or cluster case of SARS-CoV-2? related to Yellow Fever Disease", "completion": "A suspected case can be any person with acute respiratory illness (Temperature greater 37.5\u00b0C and at least one sign/symptom of respiratory infection such as cough or shortness of breath) and no other cause that fully explains the clinical presentation and no other history that fully explains the clinical presentation. This can be a person with a history of travel in the last 14 days before onset to an area reporting local transmission of COVID-19, a person requiring hospitalization, or a person with a history of contact with a confirmed or probable COVID-19 Case in the last 14 days before development of symptoms."}, {"prompt": "What criteria define a suspected sporadic or cluster case of SARS-CoV-2? related to Yellow Fever Disease", "completion": "A suspected case can be any person with acute respiratory illness (Temperature greater 37.5\u00b0C and at least one sign/symptom of respiratory infection such as cough or shortness of breath) and no other cause that fully explains the clinical presentation and no other history that fully explains the clinical presentation. This can be a person with a history of travel in the last 14 days before onset to an area reporting local transmission of COVID-19, a person requiring hospitalization, or a person with a history of contact with a confirmed or probable COVID-19 Case in the last 14 days before development of symptoms."}, {"prompt": "What defines a suspected community transmission pattern case of SARS-CoV-2? related to Yellow Fever Disease", "completion": "Any person or groups of persons with flu like symptoms such as fever, running nose, sneezing, sore throat and difficulty in breathing."}, {"prompt": "What is the case definition for a probable case of SARS-CoV-2? related to Yellow Fever Disease", "completion": "A probable case is a suspect case for whom tests for COVID-19 are inconclusive OR a suspect case for whom tests could not be performed for any reason."}, {"prompt": "What defines a probable case of SARS-CoV-2? related to Yellow Fever Disease", "completion": "A probable case is a suspect case for whom tests for COVID-19 are inconclusive OR a suspect case for whom tests could not be performed for any reason."}, {"prompt": "What is the standard case definition for a confirmed case of SARS-CoV-2? related to Yellow Fever Disease", "completion": "A confirmed case is a person with confirmed COVID-19 infection irrespective of the presence of clinical signs and symptoms. Any person who experienced any one of the following exposures during the 2 days before and the 14 days after the onset of symptoms of a probable or confirmed case is considered a contact: 1. Face-to-face contact with a probable or confirmed case within 2 meters and for more than 15 minutes; 2. Direct physical contact with a probable or confirmed case; 3. Direct care for a patient with probable or confirmed COVID-19 disease without using proper Personal Protective Equipment (PPE)."}, {"prompt": "How can a confirmed case of SARS-CoV-2 be defined? related to Yellow Fever Disease", "completion": "A confirmed case is a person with confirmed COVID-19 infection irrespective of the presence of clinical signs and symptoms. Any person who experienced any one of the following exposures during the 2 days before and the 14 days after the onset of symptoms of a probable or confirmed case is considered a contact: 1. Face-to-face contact with a probable or confirmed case within 2 meters and for more than 15 minutes; 2. Direct physical contact with a probable or confirmed case; 3. Direct care for a patient with probable or confirmed COVID-19 disease without using proper Personal Protective Equipment (PPE)."}, {"prompt": "What actions should be taken if a single case of SARS-CoV-2 is suspected or confirmed? related to Yellow Fever Disease", "completion": "If a single case is suspected, the individual should be reported immediately to the appropriate levels. Suspected cases should be isolated from other patients/people with at least 2 metres and strict infection prevention procedures should be implemented. Infection Prevention and Control (IPC) precautions should be enhanced throughout the health care setting and in communities. Suspect should be instructed to wear at least a medical or cloth mask and practice appropriate hand hygiene. If possible, dedicated toilet facilities should be made available. If a single case is confirmed, strict COVID-19 infection prevention and control practices should be maintained throughout the outbreak."}, {"prompt": "What steps should be taken in response to a suspected or confirmed case of SARS-CoV-2? related to Yellow Fever Disease", "completion": "If a single case is suspected, the individual should be reported immediately to the appropriate levels. Suspected cases should be isolated from other patients/people with at least 2 metres and strict infection prevention procedures should be implemented. Infection Prevention and Control (IPC) precautions should be enhanced throughout the health care setting and in communities. Suspect should be instructed to wear at least a medical or cloth mask and practice appropriate hand hygiene. If possible, dedicated toilet facilities should be made available. If a single case is confirmed, strict COVID-19 infection prevention and control practices should be maintained throughout the outbreak."}, {"prompt": "How should data about an individual with SARS-CoV-2 be analyzed and interpreted? related to Yellow Fever Disease", "completion": "Initiate immediate case-based reporting of cases and deaths. Analyze age and sex distribution. Assess risk factors and plan outbreak response interventions accordingly."}, {"prompt": "What are the methods to analyze data about an individual with SARS-CoV-2? related to Yellow Fever Disease", "completion": "Initiate immediate case-based reporting of cases and deaths. Analyze age and sex distribution. Assess risk factors and plan outbreak response interventions accordingly."}, {"prompt": "How can we interpret the data about an individual with SARS-CoV-2? related to Yellow Fever Disease", "completion": "Initiate immediate case-based reporting of cases and deaths. Analyze age and sex distribution. Assess risk factors and plan outbreak response interventions accordingly."}, {"prompt": "How to analyze and interpret data about time in the context of SARS-CoV-2? related to Yellow Fever Disease", "completion": "Plot a graph of cases and deaths daily/weekly. Construct an epidemic curve during the outbreak."}, {"prompt": "What are the techniques used for temporal analysis of SARS-CoV-2 data? related to Yellow Fever Disease", "completion": "Plot a graph of cases and deaths daily/weekly. Construct an epidemic curve during the outbreak."}, {"prompt": "How can temporal analysis help in understanding SARS-CoV-2 trends? related to Yellow Fever Disease", "completion": "Plot a graph of cases and deaths daily/weekly. Construct an epidemic curve during the outbreak."}, {"prompt": "How to analyze and interpret data about place in the context of SARS-CoV-2? related to Yellow Fever Disease", "completion": "Map locations of cases' households and work sites using available national systems."}, {"prompt": "What are the methods used for spatial analysis of SARS-CoV-2 data? related to Yellow Fever Disease", "completion": "Map locations of cases' households and work sites using available national systems."}, {"prompt": "How can spatial analysis contribute to understanding SARS-CoV-2 transmission? related to Yellow Fever Disease", "completion": "Map locations of cases' households and work sites using available national systems."}, {"prompt": "What is the laboratory confirmation diagnostic test for SARS-CoV-2? related to Yellow Fever Disease", "completion": "Diagnostic test: Viral and antibody tests. Diagnosis is confirmed by the presence of Viral RNA detected by molecular testing, usually RT-PCR."}, {"prompt": "What are the laboratory confirmation specimen types for SARS-CoV-2? related to Yellow Fever Disease", "completion": "Nasal or Oropharyngeal swab."}, {"prompt": "When should specimens be collected for laboratory confirmation in the context of SARS-CoV-2? related to Yellow Fever Disease", "completion": "For each new area affected by the outbreak, laboratory confirmation should be done. Collect nasal or oral pharyngeal swab from suspected COVID-19 cases or contacts of confirmed cases.Provide for treatment based on symptoms for mild case and severe cases (refer to treatment guidelines for COVID-19)"}, {"prompt": "How to prepare, store, and transport specimens for laboratory confirmation in the context of SARS-CoV-2? related to Yellow Fever Disease", "completion": "Use flexible Nasopharyngeal/Oropharyngeal swab to collect specimens, leave swab in place for several seconds to absorb secretions. Slowly remove the swab while rotating it. Place specimen (nasal or oropharyngeal swab) in viral transport media (VTM), triple packaged and labeled appropriately. Store collected specimens at temperatures of 2 \u2013 8 \u00b0C until ready to send to the reference laboratory. Specimens may be held at this temperature for up to 72 hours. Specimens must be received reference Laboratories within three days of being collected."}, {"prompt": "What are the results of laboratory confirmation for SARS-CoV-2? related to Yellow Fever Disease", "completion": "COVID-19 tests may not be routinely performed in all laboratories. Return and communication of results is done through centralized electronic result download system. Results are uploaded into this system by accredited COVID -19 testing laboratories into electronic results dispatch system (eRDS). Results are always received within 48 to 72 hours. The country along with the neighbours have set up the Regional Electronic data and driver tracking system (RECDTS) in 15 points of entry at the border posts which enables access to results of tested truck drivers by the authorities."}, {"prompt": "Where can I find more information about SARS-CoV-2? related to Yellow Fever Disease", "completion": "1. Benjamin J Cowling, Allison E Aiello, Public Health Measures to Slow Community Spread of Coronavirus Disease 2019, The Journal of Infectious Diseases, doi: https://doi.org/10.1093/infdis/jiaa123.\n2. WHO. Coronavirus disease 2019 (COVID-19) Situation Report 91.\n3. Coronavirus: The four stages of a global pandemic; 2020. Available from: https://economictimes.indiatimes.com/news/politics-and-nation/coronavirus-the-four-stages-of-a-global-pandemic/stage-1/slideshow/74884278.cms.\n4. WHO. Coronavirus disease 2019 (COVID-19) Situation Report 72.\n5. WHO. Responding to community spread of COVID-19, Interim Guidance. 202.\n6. National guidelines for management of COVID-19 in Uganda, 2020."}]