diff --git a/outputs/headers_footers/d76a8019c0c56d1c9e67b53e4abeb2d97fc4bf35_page_8_pg1_repeat1.md b/outputs/headers_footers/d76a8019c0c56d1c9e67b53e4abeb2d97fc4bf35_page_8_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e8481f43dee7577bc597964ca295f99aa0e2995f --- /dev/null +++ b/outputs/headers_footers/d76a8019c0c56d1c9e67b53e4abeb2d97fc4bf35_page_8_pg1_repeat1.md @@ -0,0 +1,146 @@ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
TOTAL82,056
Kaizer Meyer Olkin Measure of Sampling Adequacy,783
Bartlett Test of Sphericity Chi-Square1134,787
Factor Namedf55
Sig.,000
FactorFactor ExtractionReliability Analysis
Items
Loadings(%)(Cronbach Alpha)
ConcreteSales,86561,188,919
PerformanceFinancial Performance,842
Profitability,822
AbstractMarket Share,821
Reaching Goals,807
Handling difficulties,89013,113,753
PerformanceHR quality,772
Meeting expectations,585
TOTAL74,301
Kaizer Meyer Olkin Measure of Sampling Adequacy,875
Bartlett Test of Sphericity Chi-Square721,745
df28
Sig.,000
+ +### 4.4. Descriptive Statistics and Correlations + +80,9% of the participants are upper level manager. Rest of them are middle and lower level manager. 80,1% of the respondents are man, and 19,9 % of them are woman. Their average age is 41,18. 46,1% of the respondents are bachelor; 22,7% of them have master, %2,8 have PhD degree. 57,4% of the respondents have more than 5000 TL (>3300 \$) of monthly income, 16,3 % of them have 4000-5000 TL and 19,9 % of them have 3000-4000 TL monthly income. 34% of the respondents have an experience more than 15 years and 20,6% of them have an experience of 5-10 years. + +When we look at the descriptive statistics of the factors at Table 3, we can see that the commander style in leadership is very common (M=3,93) and symbolic leadership follows it (M=3,52). In these firms, rational-transactive leadership is rarely followed (M=2,88). Corporate Entrepreneurship level of the companies in Istanbul is perceived very optimistic. For example innovativeness of these firms are perceived very high (M=3,34) and the other factors of corporate entrepreneurship which are proactiveness(M=3,07), self renewal(M=3,01), new business venturing (M=3,11) are not so low. We can also say that the optimism of the participants persists in going on about the firm performance (M=3,61 and M=3,54). diff --git a/outputs/headers_footers/d8b9c4cd0ba9b036e09168c8dccccd1d43315ef4_page_1_pg1_repeat1.md b/outputs/headers_footers/d8b9c4cd0ba9b036e09168c8dccccd1d43315ef4_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1a4a514f36a10f00086ac77068b8a3d64e9e0d01 --- /dev/null +++ b/outputs/headers_footers/d8b9c4cd0ba9b036e09168c8dccccd1d43315ef4_page_1_pg1_repeat1.md @@ -0,0 +1,25 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +LIETUVOS RESPUBLIKOS TEISINGUMO MINISTERIJA + +Biudžetinė įstaiga, Gedimino pr. 30, LT-01104 Vilnius, tel. (8 5) 266 2933, faks. (8 5) 262 5940, el. p. rastine@tm.lt, atsisk. sąskaita LT267044060000269484 AB SEB bankas, banko kodas 70440. Duomenys kaupiami ir saugomi Juridinių asmenų registre, kodas 188604955 + +Lietuvos Respublikos teismams + +2015-03-24 Nr. (1.13.)77-2035 + +Kopijos Kalėjimų departamentui prie Lietuvos Respublikos teisingumo ministerijos + +Viešojo saugumo tarnybai prie Lietuvos Respublikos vidaus reikalų ministerijos + +Lietuvos kriminalinės policijos biuro Tarptautinių ryšių valdybai + +DĖL NUOSPRENDŽIŲ, KURIAIS PASKIRTOS LAISVĖS ATĖMIMO BAUSMĖS AR SU LAISVĖS ATĖMIMU SUSIJUSIOS PRIEMONĖS, PRIPAŽINIMO IR VYKDYMO SANTYKIUOSE SU NORVEGIJOS KARALYSTE + +Siekdama palengvinti teismų darbą ir atkreipti dėmesį į pasikeitusį teisinį reguliavimą nuteistųjų asmenų perdavimo srityje su Norvegijos Karalyste, Lietuvos Respublikos teisingumo ministerija parengė aplinkraštį dėl Lietuvos Respublikos Vyriausybės ir Norvegijos Karalystės Vyriausybės Susitarimo dėl nuosprendžių baudžiamosiose bylose, kuriais paskirtos laisvės atėmimo bausmės ar su laisvės atėmimu susijusios priemonės, pripažinimo ir vykdymo (toliau – Susitarimas). + +Susitarimas santykiuose tarp Lietuvos Respublikos ir Norvegijos Karalystės pakeitė iki šiol galiojusias 1983 m. Europos konvenciją dėl nuteistųjų asmenų perdavimo ir jos 1997 m. Papildomą protokolą, 1970 m. Europos konvenciją dėl tarptautinio baudžiamųjų nuosprendžių pripažinimo bei 1990 m. Konvencijos dėl 1985 m. Šengeno susitarimo dėl laipsniško bendrų sienų kontrolės panaikinimo įgyvendinimo III antraštinės dalies 5 skyrių. + +Susitarime nustatytos taisyklės, pagal kurias susitariančioji šalis, siekdama sudaryti palankesnes sąlygas nuteistojo asmens socialinei reabilitacijai, pripažįsta nuosprendį ir vykdo bausmę. Užuot vadovavusis keliais teisiniais pagrindais, sukurtas vienas, skirtas nuosprendžiams vykdyti tiek tais atvejais, kai nuteistas asmuo yra išduodančiojoje valstybėje, tiek tuomet, kai jis dėl tam tikrų priežasčių fiziškai yra savo pilietybės valstybėje. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/headers_footers/d93aa3ed6cf33401e7427cff9f1feada5bae46e7_page_4_pg1_repeat1.md b/outputs/headers_footers/d93aa3ed6cf33401e7427cff9f1feada5bae46e7_page_4_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1f010ecb3d53dac594264c64449a5eecfc30556d --- /dev/null +++ b/outputs/headers_footers/d93aa3ed6cf33401e7427cff9f1feada5bae46e7_page_4_pg1_repeat1.md @@ -0,0 +1,89 @@ +thermocycling18. Reduced flexural strength after thermocycling process can be explained by water absorption of resin material which leads to PMMA molecules polarization and subsequently water molecules spread into inter-polymer chain. + +# Conclusion + +thermocycling conditions compared to Meliodent, and Vertex resins, and even after the thermal cycles, it have the highest flexural strength compared to the four types of acrylic resin. The flexural strengths of all resins were significantly reduced after thermocycling. + +# Conflict of Interests + +### None Declared ■ + +## Mead way resin have the highest flexural strength in non-___________________________________________________________________________________________________ + +## References + +1. Lee HH, Lee CJ, Asaoka K. Correlation in the mechanical + +properties of acrylic denture base resins. Dent Mater J 2012 Feb;31(1):157-64. + +2. Polyzois GL, Zissis AJ, Yannikakis SA. The effect of + +glutaraldehyde and microwave disinfection on some properties of acrylic denture resin. Int J of Prosthodont 1995 Mar-Apr;8(2):150-4. + +3. Patterson JC Jr. A technique for accurate soldering. J Prosthet + +Dent 1972 Nov;28(5):552-6 + +4. Oliveira LV, Mesquita MF, Henriques GE, Consani RL, Fragoso WS. Effect of polishing technique and brushing on surface roughness of acrylic resins. J Prosthodont 2008 Jun;17(4):308-11 + +5. Braun KO, Mello JA, Rached RN, Del Bel Cury AA. Surface + +texture and some properties of acrylic resins submitted to chemical polishing. J Oral Rehabil 2003 Jan;30(1):91-8. + +6. Rahal JS, Mesquita MF, Henriques GE, Nobilo MA. Surface + +roughness of acrylic resins submitted to mechanical and chemical polishing. J Oral Rehabil 2004 Nov;31(11):1075-9. + +7. Dhole RI, Srivatsa G, Shetty R, Huddar D, Sankeshwari + +B, Chopade S.Reinforcement of Aluminum Oxide Filler on the Flexural Strength of Different Types of Denture Base Resins: An In vitro Study. J Clin Diagn Res 2017 Apr;11(4):ZC101-ZC104. + +8. Ali IL, Yunus N, Abu-Hassan MI. Hardness, flexural strength, and flexural modulus comparisons of three differently cured denture base systems. J Prosthodont 2008 Oct;17(7):545-9. + +9. Ozkomur A, Fortes CB. Effects of postpolymerization + +microwave irradiation on provisional dental acrylics: physical and mechanical properties. J Appl Biomater Funct Mater 2016 Jul 26;14(3):e302-6. + +10. Swaney AC, Paffenbarger GC, Caul HJ, Sweeney WT. American Dental Association specification No. 12 for denture + +base resin: second revision. J Am Dent Assoc 1953 Jan; 46(1); 54-66. + +11. + +Machado AL, Puckett AD, Breeding LC, Wady AF, Vergani CE. Effect of thermocycling on the flexural and impact strength of urethane\(‐\text{based and high}‐\)impact denture base resins. Gerodontology 2012 Jun;29(2):e318-e23. + +12. + +Radzi Z, Kasim A, Hayaty N, Yahya N, Gan SN, Daud N, et al. Impact strength of an experimental polyurethane-based polymer. Annals Univ Dent Malaya 2007;14:46-51. + +13. + +Gungor H, Gundogdu M, Alkurt M, Yesil Duymus Z. Effect of polymerization cycles on flexual strengths and microhardness of different denture base materials. Dent Mater J 2017 Mar 31;36(2):168-173. + +14. + +Machado AL, Puckett AD, Breeding LC, Wady AF, Vergani CE. Effect of thermocycling on the flexural and impact strength of urethane-based and high-impact denture base resins. Gerodontology 2012 Jun;29(2):e318-23. + +15. + +Memon MS, Yunus N, Razak AA. Some mechanical properties of a highly cross-linked, microwave-polymerized, injection-molded denture base polymer. Int J Prosthodont 2001 May-Jun;14(3):214-8. + +16. + +Hemmati MA, Vafaee F, Allahbakhshi H. Water Sorption and Flexural Strength of Thermoplastic and Conventional Heat-Polymerized Acrylic Resins. J Dent (Tehran) 2015 Jul;12(7):478-84. + +17. + +Takahashi Y, Hamanaka I, Shimizu H. Effect of thermal shock on mechanical properties of injection-molded thermoplastic denture base resins. Acta odontol Scand 2012 Jul;70(4):297- + +18. + +302. + +Sasaki H, Hamanaka I, Takahashi Y, Kawaguchi T. Effect of long-term water immersion or thermal shock on mechanical properties of high-impact acrylic denture base resins. Dent Mater J 2016;35(2):204-9. + +_________ _______ _______ __---_--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- + +## How to cite: + +Rahab Ghoveizi, Sara Tavakolizadeh, Aida Raftarifarimani, Argin Barzanji. Comparative study of flexural strength of four acrylic resins before and after thermocycling process. J Dent Sch 2018;36(3):95-98. diff --git a/outputs/headers_footers/d9e9df46c4580bbf353bb120bd310e737d1da5e0_page_13_pg1_repeat1.md b/outputs/headers_footers/d9e9df46c4580bbf353bb120bd310e737d1da5e0_page_13_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ccbd59b5dd3cb020f889d284fa339c4d91bda88f --- /dev/null +++ b/outputs/headers_footers/d9e9df46c4580bbf353bb120bd310e737d1da5e0_page_13_pg1_repeat1.md @@ -0,0 +1,27 @@ +![](figure) + +useful to extend to a broader population including elderly participants. Spatial ability assessment provides the potential to act as an early stage diagnostic tool for Alzheimer’s dementia (AD), because spatial disorientation is one of the earliest symptoms [24, 44–48]. Currently there is no standardized test for navigation deficits with AD patients, as diagnostics measures are still focused on episodic memory deficits, despite their low sensitivity and specificity for identifying at-risk individuals [26]. Sea Hero Quest wayfinding task having real-world ecological validity holds future promise for controllable, sensitive, safe, low-cost, and easy to administer digital cognitive assessment. + +# Supporting information + +S1 Fig. Wayfinding virtual task. Maps of wayfinding Sea Hero Quest levels 1, 6, 11, 16 and + +43. Starting position and facing direction are indicated by a pale blue arrow, ordered goals by red flags. Participants must memorize the map, and then navigate towards the goals in the right order as quick as possible. (PDF) + +S2 Fig. Wayfinding real-world task in London (UK). Maps of real-world wayfinding routes (top). Starting position and facing direction are indicated by a yellow arrow, ordered goals by red dots. Participants must memorize the map, and then walk towards the goals in the right order as quick as possible. Goals are materialized by remarkable doors (bottom). (PDF) + +S3 Fig. Wayfinding real-world task in Paris (France). Maps of real-world wayfinding routes (top). Starting position and facing direction are indicated by a green arrow, ordered goals by yellow dots. Participants must memorize the map, and then walk towards the goals in the right order as quick as possible. Goals are materialized by remarkable facade (bottom). (PDF) + +S4 Fig. Path integration task in the virtual and real-world environments. A—Maps of Sea Hero Quest path integration levels 14, 34, 44, 54 and 74. B—Itineraries of the path integration task in Paris (France). Each color corresponds to a different itinerary. (PDF) + +S5 Fig. Path integration gender effect. Gender differences for the path integration task in the video game (right) and in the real world (left) in Paris. In the real world, path integration performance is the opposite of the average error angle. In the video game, path integration performance is the average number of stars. Both measures have been standardized for comparison. Black dots represent individual data points. Error bars represent standard errors. (PDF) + +S1 Video. Visualization of the wayfinding task in London and in the video game. Credits to OpenStreetMap contributors. (MP4) + +# Acknowledgments + +We thank Emmanuelle Bourigault and Mariam Yusuf for help in collecting pilot data in London. + +# Author Contributions + +Conceptualization: Lena Coutrot, Michael Hornberger, Hugo J. Spiers. diff --git a/outputs/headers_footers/dc85182643bd0e5312833dc235e3f9423cb3a9c8_page_37_pg1_repeat1.md b/outputs/headers_footers/dc85182643bd0e5312833dc235e3f9423cb3a9c8_page_37_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..01b5ac9c25502c35193235523298037f37595839 --- /dev/null +++ b/outputs/headers_footers/dc85182643bd0e5312833dc235e3f9423cb3a9c8_page_37_pg1_repeat1.md @@ -0,0 +1,31 @@ +41, 52], Zn2+ [41, 53-55], Sr2+ [25, 56], Pb2+ [57], etc., the replacement of PO43ˉ by + +HPO42ˉ [58], CO32ˉ [40, 41, 59-62] or SiO44ˉ [63-65], and OHˉ by Fˉ [29, 41, 66-68] + +or Clˉ [69]. In this review, the substitution of different kinds of cations and anions + +into HA will be extensively studied, with emphasis on the substitution effect on the + +phase evolution, mechanical and biological properties. + +#### 2.3.1 Incorporation of cation into HA + +The chemical composition of hexagonal HA (within the ideal P63/m space group) is + +Ca(I)4Ca(II)6(PO4)6(OH)2 (c.f. Figure 2-1). The local atomic configurations are + +displayed in Figure 2-4. The Ca(I) site is surrounded by six PO43ˉ tetrahedral and + +coordinated by nine oxygen ions. The Ca(II) site is seven coordinated with six + +oxygen ions from PO43ˉ and one oxygen ion from OHˉ [70, 71]. It has been + +reported that the larger cations usually occupy the Ca(II) sites and the smaller ones + +prefer the Ca(I) sites, because the nearest distance among Ca(I) sites is smaller than + +that among Ca(II) sites [72]. The substitution of cations into HA tends to cause the + +HA structure disordering, and influence the phase, mechanical and biological + +properties. diff --git a/outputs/headers_footers/dd9587961183e62e57bbcb75b084ca4066a726c2_page_3_pg1_repeat1.md b/outputs/headers_footers/dd9587961183e62e57bbcb75b084ca4066a726c2_page_3_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e767e122a0b786819efd747425888220f19e3434 --- /dev/null +++ b/outputs/headers_footers/dd9587961183e62e57bbcb75b084ca4066a726c2_page_3_pg1_repeat1.md @@ -0,0 +1,23 @@ +![](figure) + +![](figure) + +FIG. 1 (color online). Shaded (normalized) isocontours of \(A_{z}\) in the \((x;y)\) plane at \(z0,t30\) in the asymmetric case. Minimum and maximum values are \(0:002\). + +\[k_{?}^{-1}\] + +values are represented by the darker (lighter) regions, corresponding to a clockwise (counterclockwise) magnetic field. This figure clearly shows that the resulting magnetic field is characterized, in the asymmetric case, by a bubble-like shape with typical length scale of the order of a few \(d_{e}\) both in the perpendicular and in the parallel directions, i.e., by \(k_{k}^{-1}k_{?}^{-1}d_{e}\). On the other hand, in the symmetric case, the magnetic field structures are strongly anisotropic being elongated in the beams direction, i.e., \(k_{k}^{-1} d_{e}\). Similar results (not presented here) have been obtained, aside from the localization of the magnetic field around the resonance for two initially homogeneous beams. We define the perpendicular and parallel averaged spectrum of \(A_{z}\) as the Fourier spectrum averaged along the \(z\) direction and in the \((x;y)\) plane, respectively (and the same for the total density). As expected, in both cases the perpendicular spectra increase at \(k_{?}<1\) and reach a maximum at \(k_{?}1\), corresponding to \(d_{e}\). At larger wave + +![](figure) + +![](figure) + +FIG. 2 (color online). Shaded (normalized) isocontours of \(A_{z}\) in the \((x;y)\) plane at \(z0,t25\) in the symmetric case. Minimum and maximum values are \(0:015\). + +vectors, \(k_{?}10\) the spectra decrease due to numerical dissipative effects of a filter, based on a fast-Fourier-transform algorithm, necessary for code stability [24]. Let us now discuss the longitudinal spectra which measure the characteristic length scale of the magnetic ‘‘filaments’’ in the beams’ direction. In Fig. 4, first two frames, we see that the \(A_{z}\) spectrum peaks are located at \(k_{k}’0:8\) and at \(k_{k}0\) for the asymmetric and symmetric case, respectively. This corresponds to a characteristic length scale of the order of a few \(d_{e}\) in the asymmetric case, i.e., to a ‘‘bubblelike’’ magnetic structure, and to an ‘‘infinite’’ length scale, i.e., to very long magnetic filaments, in the symmetric case. By comparing the asymmetric density spectrum, third frame, we observe the same peak at \(k_{k}’0:8\), but with a spectrum decrease towards \(k_{k}0\). Moreover, in the symmetric case the density peak is not at \(k_{k}0\), as observed for \(A_{z}\) since at \(k_{k}0\) the TS contribution is lost and the mode becomes purely electromagnetic. Furthermore, the perpendicular density spectrum (not shown here), driven by nonlinear effects, is more than 2 order of magnitude smaller than the parallel one and rapidly decreases at \(k_{?}<1\). We therefore conclude that, in this regime, the density fluctuations are mainly driven by the TS contribution. However, density perturbations will strongly change their nature in the further regime when strong nonlinear effects and charge separation effects (induced by the self generated magnetic field) become important. Our model of a relativistic beam propagating in a dense plasma shows that the Weibel instability generates bubble-like magnetic structures with typical parallel and perpendicular length scales of the order of a few \(d_{e}\). This loss of + +![](figure) + +![](figure) + +FIG. 3 (color online). Shaded isosurfaces of \(A_{z}\) at \(t30\) and \(t25\) in the asymmetric \((A_{z}0:0009)\) and symmetric \((A_{z} 0:008)\) case, left and right frame, respectively. diff --git a/outputs/headers_footers/e07711f7522a9e2938e3a7905f9eeaae817839a2_page_1_pg1_repeat1.md b/outputs/headers_footers/e07711f7522a9e2938e3a7905f9eeaae817839a2_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4b07fc8fec1625216eb607ce68fbde80e36dc0d0 --- /dev/null +++ b/outputs/headers_footers/e07711f7522a9e2938e3a7905f9eeaae817839a2_page_1_pg1_repeat1.md @@ -0,0 +1,435 @@ +# Contents + +## When we have not what we like, we must like what we have. Comte de Bussy-Rabutin + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
1Basic Graph Theory..........1
1.1 Graphs, Subgraphs and Factors..........2
1.2 Paths, Cycles, Connectedness, Trees . . ...........5
1.3 Euler Tours..........13
1.4 Hamiltonian Cycles..........15
1.5 Planar Graphs..........21
1.6 Digraphs..........25
21.7 An Application: Tournaments and Leagues.........29
Algorithms and Complexity..........35
2.1 Algorithms..........36
2.2 Representing Graphs..........38
2.3 The Algorithm of Hierholzer..........41
2.4 How to Write Down Algorithms..........44
2.5 The Complexity of Algorithms..........46
2.6 Directed Acyclic Graphs..........49
2.7 An Introduction to NP-completeness . . ...........52
32.8 Five NP-complete Problems..........56
Shortest Paths..........65
3.1 Shortest Paths..........65
3.2 Finite Metric Spaces..........68
3.3 Breadth First Search and Bipartite Graphs.........69
3.4 Shortest Path Trees..........74
3.5 Bellman’s Equations and Acyclic Networks.........76
3.6 An Application: Scheduling Projects . . ...........79
3.7 The Algorithm of Dijkstra..........83
3.8 An Application: Train Schedules..........88
3.9 The Algorithm of Floyd and Warshall . ...........91
3.10 Cycles of Negative Length..........96
3.11 Path Algebras..........97
diff --git a/outputs/headers_footers/e1877d4ffc65bd66a9e5b9a5d2608362ad458c86_page_7_pg1_repeat1.md b/outputs/headers_footers/e1877d4ffc65bd66a9e5b9a5d2608362ad458c86_page_7_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..dfae3dd1b2a0a18106e479e3e1d5d943311fe380 --- /dev/null +++ b/outputs/headers_footers/e1877d4ffc65bd66a9e5b9a5d2608362ad458c86_page_7_pg1_repeat1.md @@ -0,0 +1,9 @@ +570 Mio. Da spiele etwas nicht. Man könne nicht zuerst Kredite verlangen und dann solche Änderungen vornehmen ohne den Bundesrat und evt. die eidg. Räte zu orientieren. Herr Chaudet bemerkt, dass die KTA vorsichtshalber noch eine Teuerungsreserve von 100 Mio. vorgesehen habe. Der schweizerische Mirage unterscheide sich vom französischen, vor allem durch die Elektronik. Man könne uns kaum einen Vorwurf machen, dass wir die beste Elektronik wollten. Das Profil des Flugzeuges bleibe das gleiche, es bleibe ein Mirageflugzeug. Der Sprechende wiederholt, dass die Zahlen sehr vorsichtig gerechnet worden seien. Für die Luftverteidigung werde man einen Plafond von 2,5 Milliarden nicht übersteigen. Herr Bonvin kann dem zustimmen, wünscht aber, dass man in der Botschaft die Widersprüche rechtfertige, mit dem was man 1961 erklärt habe[^30]. Der Herr Bundespräsident stellt fest, dass der Rat heute dem Botschaftsentwurf nicht zustimme. Herr Spühler wünscht, dass in der Botschaft militärpolitische Überlegungen gemacht werden. Herr Chaudet nimmt von dieser Anregung Kenntnis. Die Botschaft könne Ende März oder Anfangs April herauskommen. Es wird beschlossen, dass die Miragebotschaft den eidg. Räten jetzt angekündigt werden soll. [...][^31] + +[^30]: Handschriftliche Marginalie von F. Weber: Er wird den Mitgliedern noch Vergleichsta- + +bellen zukommen lassen. + +[^31]: Für das vollständige Dokument vgl. dodis.ch/31973. Zum weiteren Verlauf der Mirage- + +Affäre vgl. Dok. 180, dodis.ch/32042, Anm. 7. diff --git a/outputs/headers_footers/e21f9a882b1d0863c127fbc7da563a20232044d2_page_1_pg1_repeat1.md b/outputs/headers_footers/e21f9a882b1d0863c127fbc7da563a20232044d2_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6cfd95a370378186e14fc64eb014c6fa34a37ed3 --- /dev/null +++ b/outputs/headers_footers/e21f9a882b1d0863c127fbc7da563a20232044d2_page_1_pg1_repeat1.md @@ -0,0 +1,11 @@ +# Residence and Dining Facilities + +The Yale Housing Office has dormitory and apartment units available for graduate and professional students. Dormitories are single-occupancy and two-bedroom units of varying sizes and prices. They are located across the campus, from Edward S. Harkness Memorial Hall, serving the medical campus, to Helen Hadley Hall and the newly built 272 Elm Street, serving the central/science campus. Unfurnished apartments consisting of efficiencies and one-, two-, and three-bedroom apartments for singles and families are also available. Family housing is available in Whitehall and Esplanade Apartments. The Housing website (https://housing.yale.edu) is the venue for graduate housing information and includes dates, procedures, facility descriptions, floor plans, and rates. Applications for the new academic year are available beginning April 20 and can be submitted directly from the website with a Yale NetID. The Yale Housing Office also manages the Off Campus Living listing service (http://offcampusliving.yale.edu; 203.436.9756), which is the exclusive Yale service for providing off-campus rental and sales listings. This secure system allows members of the Yale community to search rental listings, review landlord/property ratings, and search for a roommate in the New Haven area. On-campus housing is limited, and members of the community should consider off-campus options. Yale University discourages the use of Craigslist and other third-party nonsecure websites for off-campus housing searches. The Yale Housing Office is located in Helen Hadley Hall (HHH) at 420 Temple Street and is open from 9 a.m. to 4 p.m., Monday through Friday; 203.432.2167. + +### Edward S. Harkness Memorial Hall + +Harkness Hall, located only steps away from the School of Medicine and Yale New Haven Hospital, houses students from the Schools of Medicine, Nursing, and Public Health, the Physician Associate program, and other graduate and professional schools at Yale. Residents of Harkness Hall live in a secure building with single-occupancy bedrooms. Yale administrative offices occupy the first through third floors of the building. The great advantages of living in Harkness Hall are its close proximity to classes and the opportunity it provides in bringing together students from the various medical-related fields in a relaxed social setting. For additional information visit https:// housing.yale.edu. + +### Café Med + +Café Med, located in Harkness Hall at the School of Medicine, is open from 7:30 a.m. to 7 p.m., Monday through Friday. The menu enhances convenience and choice, with a customizable salad, soup, and rice bar utilizing local and seasonal ingredients; specialty coffees and fresh pastries; a grab-and-go selection of freshly made salads, sandwiches, and entrées; and a daily hot food option. For additional information visit https://hospitality.yale.edu/retail/cafe-med. diff --git a/outputs/headers_footers/e323236139bd81ae8d62de9ed3826d6e8007a71e_page_12_pg1_repeat1.md b/outputs/headers_footers/e323236139bd81ae8d62de9ed3826d6e8007a71e_page_12_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a516ae44c699dc02e4d7f9ac07f492b2aeaf74b4 --- /dev/null +++ b/outputs/headers_footers/e323236139bd81ae8d62de9ed3826d6e8007a71e_page_12_pg1_repeat1.md @@ -0,0 +1,78 @@ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
StofHvor kommer det fra?Hvad fortæller det om?
16O-, 17O- og 18O-isotoper i isenHavet via skyer til sneTemperaturen i luften
Uopløselige mikropartikler (støv)Vindblæst støv fra kontinenterne (hovedsagelig fra Asien), mikrometeoritter fra rummet, vulkansk aske og biologisk materialeVindaktiviteten, vindretninger, størrelsen af ørkenområder, solsystemets oprindelse, hvilke vulkaner der har været i udbrud, dyre- og planteliv
SaltHavsalt fra havetStorme over havet, udbredelse af havis, vindsystemer
Salpetersyre og ammoniumBiologiske processer ved varmere breddegrader, lynudladninger, industri og landbrugDen biologiske aktivitet, skovbrande og forureningen fra bilkørsel, industri og landbrug
Svovlsyre, saltsyre, flussyreBiologiske processer, vulkanudbrud, olie- og kulafbrændingDen biologiske aktivitet, vulkanudbrud og moderne forurening
Calcium- og magnesiumkarbonaterOpløst kontinentalt støvVindaktivitet, vindretninger og ørkenområder
Drivhusgasserne kuldioxyd og metanBiologiske processer i havet og på kontinenterne, afbrænding af fossilt brændstof, moderne landbrugGraden af biologisk aktivitet, vekselvirkningen mellem drivhusgasserne og klimaet
Kunstige gasserFreon fra køleanlæg og industriGraden af forurening med gasser, som ødelægger atmosfærens ozonlag
Tungmetaller, f.eks. blyBlyudvinding og afbrænding, minedrift og industriGraden af blyforurening, belastningen af det arktiske miljø fra tungmetaller
Kulstof-14, beryllium-10 ogNaturlige radioaktive stofferKosmisk stråling, Solens stråleintensitet og
klor-36Jordens magnetfelt; alder
Cæsium-137 og strontium-90Menneskeskabte radioaktive stofferAtombombesprængninger og A-kraftværksulykker
DNABiologisk arvematerialeTidligere tiders plante- og dyreliv
+ +Ved at undersøge, hvorledes syren fra et givet udbrud fordeler sig i årlagene, kan vi desuden bestemme, om udbruddet er sket langt fra Grønland, f.eks. i Indonesien eller i Middelhavet, tættere på, f.eks. i Alaska, eller helt tæt på, i Island. Vesuvs udbrud i år 79 efter Kristi fødsel er det ældste udbrud, vi har historiske kilder om. Det var dette udbrud, som begravede de romerske byer Pompeji og Herculanum uden for Napoli. Det forhold, at vi finder spor af udbruddet netop i det rigtige år, bekræfter, at vi tæller rigtigt i vores bestemmelser af årlag. Tidspunktet for udbruddet, eller rettere eksplosionen af øen Santorini (Thera) i det Ægæiske Hav har stor arkæologisk betydning. Udbruddet skete i den minoiske periode, og både selve eksplosionen og den efterfølgende flodbølge ødelagde mange havnebyer i Middelhavet. Ved at datere arkæologiske fund bl.a. med kulstof 14-metoden mente arkæologerne, at udbruddet skete 1400-1500 år f.Kr. Der har dog været stor usikkerhed om tidspunktet. Iskernerne viser et lag med svovlsyre i år 1643 f.Kr. Imidlertid kan man ikke ud fra svovlsyren alene bestemme, om dette lag virkelig stammer fra Santorini. Svovlsyre er svovlsyre, så det kunne komme fra en anden vulkan. Men ved at tage prøver ud fra iskernen i netop dette lag har man fundet mikroskopiske askepartikler. Og disse askepartiklers kemiske sammensætning har Santorinis kemiske »fingeraftryk«. Vi er derfor overbevist om, at Santorini i Grækenland eksploderede mellem år 1636 og år 1646 f.Kr. Vi regner nemlig med, at vi højst har talt 10 år forkert i denne dybde af iskernen. + +# Aldersbestemmelse dybt nede i isen + +Efterhånden som lagene synker dybere ned i isen, bliver de tyndere, og samtidig diffunderer 16O- og 18Oisotoperne i isen så forskellene mellem sommer- og vintersne langsomt bliver udvisket. Vi kan derfor ikke tælle årlag med isotoper hele vejen ned. Det viser sig, at mange andre af de målte stoffer også har sæsonmæssige udsving, og de overtager rollen som årlagsindikatorer. Særligt isens indhold af uopløselige mikropartikler viser sig at være en god dateringsparameter. De store forårsstorme bringer nemlig store mængder støv ind over isen, således at vi kan se forhøjede koncentrationer af uopløselige mikropartikler i forårsla- diff --git a/outputs/headers_footers/e4ace7edb587a91a895b3ed38e13e1a6c704dd26_page_1_pg1_repeat1.md b/outputs/headers_footers/e4ace7edb587a91a895b3ed38e13e1a6c704dd26_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..20e1ba4f459d9fa0ed8feed89f3ccfe6cf349a1f --- /dev/null +++ b/outputs/headers_footers/e4ace7edb587a91a895b3ed38e13e1a6c704dd26_page_1_pg1_repeat1.md @@ -0,0 +1,15 @@ +# TÓXICOS E GUERRAS + +## HUMBERTO EUSTÁQUIO SOARES MARTINS* + +## Desembargador do Tribunal de Justiça de Alagoas + +A Organização das Nações Unidas, ONU, recomenda a todas as nações a fixação de impostos mais altos para bebidas alcoólicas e fumo, assim como medidas especiais de proteção para segmentos da população que julga mais frágeis e vulneráveis, tais como profissionais do sexo e usuários de drogas injetáveis. Recomenda também que a publicidade de bebidas alcoólicas seja limitada. Esses segmentos estão em situação de alto risco, no que concerne ao consumo de tóxicos e ao alcoolismo. + +A maconha é a droga mais consumida pela juventude, porém, nos últimos anos, tem ocorrido um enorme crescimento do uso de substâncias sintéticas. Embora reconheça o esforço da maior parte das nações para conter a utilização de estimulantes ilícitos, a ONU destaca que os jovens consomem cada vez mais pílulas, como o ecstasy, principalmente em locais de diversão. + +Nas nações subdesenvolvidas, inclusive no Brasil, o crescimento do consumo de drogas sintéticas ocorre mais em camadas economicamente privilegiadas, de maior poder aquisitivo. Nos países ricos, esse fenômeno é generalizado. + +Além de tóxicos e fumo, a ONU está preocupada com as conseqüências de conflitos localizados nas camadas mais jovens da população. Embora atinjam a totalidade da comunidade, as guerras localizadas prejudicam mais os jovens, que têm tolhidas assim suas oportunidades de educação e trabalho. Nessas oportunidades, crescem também as dimensões de crimes tais como a violência sexual. + +![](figure) diff --git a/outputs/headers_footers/e5bd2d41aa419ca0474bfeb7d311babe2489e01f_page_2_pg1_repeat1.md b/outputs/headers_footers/e5bd2d41aa419ca0474bfeb7d311babe2489e01f_page_2_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..232ed31df381177e5c58c236c920827954d59c4b --- /dev/null +++ b/outputs/headers_footers/e5bd2d41aa419ca0474bfeb7d311babe2489e01f_page_2_pg1_repeat1.md @@ -0,0 +1,27 @@ +## Resumen + +El trabajo aquí presentado tuvo por objetivo de identificar lecciones contemporáneas de proyecto a partir de un análisis de la producción arquitectónica y urbanística en Brasilia. Se trata de una ciudad brasileña en la que la arquitectura y el urbanismo tuvieron papel protagonista, pero que la crítica postmoderna condenó a una condición negativa de error limitando su valor a una dimensión puramente histórica considerada no pertinente como referencia de proyecto. Para poder superar ese juicio de valor y alcanzar otras posibilidades de análisis, procedemos, en un primer momento, a la lectura de textos alineados con el procedimiento del manifiesto retroactivo. A continuación, se organizaron talleres internacionales que se valieron de ese procedimiento para observar las situaciones arquitectónicas y urbanas existentes y discutir sobre las posibilidades de articulaciones teóricas con consecuente construcción de un repertorio de lecciones de proyecto. Este trabajo nos llevó a explorar la posibilidad de reinterpretación de la producción históricamente reconocida de la arquitectura y del urbanismo situados en el área del Plan Piloto de Brasilia a partir de referenciales teóricos contemporáneos, otorgando así a ella un nuevo y actualizado entendimiento. nos permitió reconocer el potencial teórico y proyectual de situaciones denominadas ordinarias encontradas sobre todo en las áreas periféricas de expansión metropolitana de la capital federal en las cuales la producción erudita de la arquitectura y del urbanismo es en general ausente pero donde fue posible encontrar sorprendentes lecciones para ser aprendidas y incorporadas a la enseñanza de teoría y diseño ofrecido por nuestras escuelas. + +## Resumo + +O trabalho aqui apresentado teve por objetivo de identificar lições contemporâneas de projeto a partir de uma análise da produção arquitetônica e urbanística em Brasília. Tratase de uma cidade brasileira em que a arquitetura e o urbanismo tiveram papel protagonista, mas que a crítica pós-moderna condenou à uma condição negativa de erro limitando seu valor a uma dimensão puramente histórica considerada não-pertinente enquanto referência de projeto. Para poder superar esse juízo de valor e alcançar outras possibilidades de análise, procedemos, num primeiro momento, à leitura de textos alinhados com o procedimento do manifesto retroativo. Em seguida, foram organizadas oficinas internacionais que se valeram desse procedimento para observação das situações arquitetônicas e urbanas existentes e discussão sobre as possibilidades de articulações teóricas com consequente construção de um repertório de lições de projeto. Esse trabalho nos levou a explorar a possibilidade de reinterpretação da produção historicamente reconhecida da arquitetura e do urbanismo situados na área do Plano Piloto de Brasília a partir de referenciais teóricos contemporâneos, conferindo assim a ela um novo e atualizado entendimento. Ele também nos permitiu reconhecer o potencial teórico e projetual de situações ditas ordinárias encontradas sobretudo nas áreas periféricas de expansão metropolitana da capital federal nas quais a produção erudita da arquitetura e do urbanismo é em geral ausente, mas onde foi possível encontrar surpreendentes lições para serem aprendidas e incorporadas ao ensino de teoria e projeto oferecido por nossas escolas. + +## Abstract + +The objective of this work was to identify contemporary design lessons based on an analysis of architectural and urban projects in Brasilia. This is a Brazilian city in which architecture and urbanism played a leading role, but which postmodern criticism erroneously condemned by limiting its value to a purely historical dimension considered to be irrelevant as a project reference. In order to overcome this value judgment and to achieve other possibilities for analysis, a number of texts aligned with the retroactive manifesto procedure were examined. Subsequently, an international workshop was organized that used this procedure to observe the existing architectural and urban situations and discuss the possibilities for theoretical coordination with the consequent construction of a repertoire of design lessons. This work led to exploring the possibility of reinterpreting the historically-recognized production of architectural and urban projects located within the area of the Brasilia Pilot Plan from the perspective of contemporary theoretical references, thus generating a new and updated understanding of the local projects. The workshop also made it possible to recognize the theoretical and design potential of so called ordinary situations encountered mainly in the peripheral areas of the metropolitan expansion of the federal capital, in which the erudite production of architecture and urbanism is generally absent, but where it was possible to find surprising lessons to be learned and incorporated into the teaching of theory and design offered by our schools. + +# PREPRINT + +También + +#### Palabras claves: + +Análisis, diseño, teoría, crítica, + +#### Palavras chaves: + +Análise, desenho, teoria, crítica, Brasília + +#### Keywords: + +Analysis, design, theory, review, Brasilia diff --git a/outputs/headers_footers/e6f5dee6efd9ab050d1d981a141dae4ab56fab95_page_2_pg1_repeat1.md b/outputs/headers_footers/e6f5dee6efd9ab050d1d981a141dae4ab56fab95_page_2_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..666d0d04f6994a506de84e99192cdbc778e05fce --- /dev/null +++ b/outputs/headers_footers/e6f5dee6efd9ab050d1d981a141dae4ab56fab95_page_2_pg1_repeat1.md @@ -0,0 +1,27 @@ +![](figure) + +![](figure) + +"We are trying to create this kind of a fiber optic waveguide on chip," Agarwal explains. "So it's like a fiber, but on a chip, and therefore what we need is a core with a high (refractive) index and a cladding with a low index." Silicon carbide and silicon oxide have a large enough difference in their refractive indices that they work together well as the core and cladding for a waveguide. + +NanoStructures Laboratory in the MIT Research Laboratory of Electronics. + +"We came up with the right type of chemistries in this reaction and controlled the gas flows and the plasma, or, in other words, the details of the processing recipe," Ma says. "This recipe is really selective to etch silicon carbide compared to silicon dioxide, which made it possible for us to shape the silicon carbide photonic devices and have a smooth waveguide sidewall," Ma says. The smooth sidewall is critical for maintaining the optical signals in the photonic device, he notes. + +The researchers achieved the record quality factor in this study using the plasma enhanced chemical (PECVD) process to deposit the silicon carbide, at a temperature that is compatible with complementary metal-oxide semiconductor (CMOS) silicon chip processing, and developing a method to pattern and etch the silicon carbide ring resonator, which is coupled to a straight waveguide. + +The main sources of light loss in these resonators are absorption of photons in the ring material and/or scattering of photons caused by edge roughness of the ring device. "Danhao's processing yielded smooth sidewalls, which enabled low loss and a high Q (quality) factor resonator," Agarwal explains. + +# Overcoming challenges + +MIT graduate student Ma overcame several processing challenges to make the high-quality resonator. When Ma began working on silicon carbide materials for this study about three years ago, there was no existing recipe for how to etch a pattern into the amorphous silicon carbide material when it is deposited on a silicon dioxide substrate. "Silicon carbide is a very rigid and physically and chemically hard material, so, in other words, it's very difficult for it to be removed or etched," Ma says. + +To deposit and etch the silicon carbide waveguide on silicon oxide, Ma first used electron beam lithography to pattern the waveguides and reactive ion dry etching to remove excess silicon carbide. But his first attempts using a typical polymer-based mask didn't work because the process removed more of the mask than the silicon carbide. Ma then tried a metal mask, but grain boundaries from the mask carried over to the silicon carbide, leaving behind rough sidewalls in the waveguides. Roughness is undesirable because it increases photon scattering and light loss. To resolve the issue, Ma developed a technique using a silicon dioxide-based mask for the reactive ion etching. During the process development, Ma worked closely with Qingyang Du, an MIT postdoc, and Mark K. Mondol, assistant director of the + +"The beauty of this silicon carbide material and the technique that we used here in the paper is that the PECVD process of silicon carbide is an inexpensive process, standard in the silicon microelectronics industry," says Ma, whose research concentration is materials design and engineering for integrated photonics. "Use of the existing microelectronics processes will make the adoption of silicon carbide into the integrated photonic and integrated electronic platforms easier." The PECVD and reactive dry ion etching processes he used don't require the lattice matching and other critical demands of epitaxial growth on silicon, and is substrate-agnostic, Ma says. + +# Better performance + +Tan has studied silicon nitride materials and other CMOS materials for their nonlinearity for several years. "For (amorphous) silicon carbide, you would have a better enhancement when cast as a resonator compared to ultra-silicon-rich nitride, and it also has a higher nonlinear refractive index than stoichiometric silicon nitride, which is prolific in nonlinear optics," Tan says. + +Several kinds of photon absorption known as two-photon and three-photon absorption are typically diff --git a/outputs/headers_footers/e71f5c5980249ece8863fa1b43c0418e4b3244fd_page_6_pg1_repeat1.md b/outputs/headers_footers/e71f5c5980249ece8863fa1b43c0418e4b3244fd_page_6_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1cd9b452895088d893f805927d8908fd131fc8fc --- /dev/null +++ b/outputs/headers_footers/e71f5c5980249ece8863fa1b43c0418e4b3244fd_page_6_pg1_repeat1.md @@ -0,0 +1,45 @@ +[14]. + +Emara, W. M., Moez, K. K., & Elkhouly, A. H. (2014). Topical versus intravenous Tranexamic Acid as a blood conservation intervention for reduction of post-operative bleeding in Hemiarthroplasty. Anesthesia, Essays and Researches, 8(1), 48–53. + +Petajl J, Myllynen I, Myllyla G, Vahtera E. Fibrinolysis after application of a pneumatic tourniquet. Acta Chir Stand 1987; 153:647- + +[15]. + +[16]. + +51. + +Ahn J, Man L-X, Park S, Sodl JF, Esterhai JL. Systematic review of cemented and uncemented Hemiarthroplasty outcomes for femoral neck fractures. Clin Orthop Relat Res 2008;466 (10):2513–8. + +[17]. + +Bierbaum, B. E. et al: An analysis of blood management in patients having a total hip or knee arthroplasty. JBJS [Am]1999, 81-A(1): 2-10. + +[18]. + +Sehat KR, Evans RL, Newman JH. Hidden blood loss following hip and knee arthroplasty.Correct management of blood loss should take hidden loss into account. J Bone Joint Surg Br. 2004;86:561–5. + +[19]. + +Na HS, Shin HJ, Lee YJ, Kim JH, Koo KH, Do SH. The effect of Tranexamic Acid on blood coagulation in Total Hip Arthroplasty arthroplasty: Rotational thromboelastographic analysis. Anaesthesia. 2016;71(1):67–75. + +[20]. + +Georgiadis AG, Muh SJ, Silverton CD et al: A prospective double-blind placebo Controlled trial of topical Tranexamic Acid in Total Knee Arthroplasty. J Arthroplasty, 2013; 28(8): S78–82. + +[21]. + +Iwai T, Tsuji S, Tomita T, Sugamoto K, Hideki Y, Hamada M. Repeat-dose intravenous Tranexamic Acid further decreases blood loss in Total Knee Arthroplasty. Int Orthop. 2013;37(3):441-5. + +[22]. + +Cap AP, Baer DG, Orman JA, Aden J, Ryan K, Blackbourne LH. Tranexamic Acid for trauma patients: a critical review of the literature. J Trauma. 2011;71:S9-14. + +[23]. + +Hynes MC, Calder P, Rosenfeld P, Scott G. The use of Tranexamic Acid to reduce blood loss during Total Hip Arthroplasty: An observational study. Ann R Coll Surg Engl. 2005;87(2):99–101. + +[24]. + +Sarzaeem MM, Razi M, Kazemian G, Moghaddam ME, Rasi AM, Karimi M. Comparing efficacy of three methods of Tranexamic Acid administration in reducing hemoglobin drop following Total Knee Arthroplasty. J Arthroplasty. 2014;29(8):1521–4. diff --git a/outputs/headers_footers/e7f89d27e9cc33c4e86d92c27cc578a95a323b24_page_1_pg1_repeat1.md b/outputs/headers_footers/e7f89d27e9cc33c4e86d92c27cc578a95a323b24_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8ba07c080d4e64b2cd422c4a2ee2e8be06ba9949 --- /dev/null +++ b/outputs/headers_footers/e7f89d27e9cc33c4e86d92c27cc578a95a323b24_page_1_pg1_repeat1.md @@ -0,0 +1,39 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +DUALITY FOR CROSSED PRODUCTS OF VON NEUMANN ALGEBRAS BY LOCALLY COMPACT GROUPS + +BY YOSHIOMI NAKAGAMI + +Communicated June 30, 1975 + +The duality for crossed products of von Neumann algebras by locally compact abelian groups has been obtained by Takesaki [4]. We shall generalize this result to a locally compact (not necessarily abelian) group by using the Fourier algebra in place of the dual group. + +Let \(G\) denote a locally compact group with a right invariant Haar measure \$dt\$ , and \(M\) denote a von Neumann algebra over a Hilbert space \(\mathcal{H}\) . By an action of \(G\) on \(M\) we mean a homomorphism \(\sigma: t \in G \mapsto \sigma_t \in \text{Aut}(M)\) such that for each \(x \in M\) the mapping \(t \in G \mapsto \sigma_t(x)\) is \(\sigma\) -strongly* continuous. Let \(\{\pi_\sigma, \lambda\}\) be a covariant representation of \(\{M, \sigma\}\) on \(\mathcal{H} \otimes L^2(G)\) defined by + +\[\begin{cases} (\pi_\sigma(x)\xi)(s) \equiv \sigma_s(x)\xi(s), & \xi \in \mathcal{H} \otimes L^2(G), \\ \lambda(r)\xi(s) \equiv \xi(sr), & r, s \in G. \end{cases}\] + +Then the crossed product \(\mathcal{R}(M; \pi_\sigma)\) of \(M\) by \(G\) is the von Neumann algebra generated by \(\pi_\sigma(M)\) and \(\lambda(G)\) . + +THEOREM 1. A necessary and sufficient condition that a mapping \(\alpha\) of \(M\) into \(M \otimes L^\infty(G)\) be induced by an action \(\sigma\) with + +\[(\alpha(x)\xi)(s) = \sigma_s(x)\xi(s), \quad x \in M, \xi \in \mathcal{H} \otimes L^2(G),\] + +is that \(\alpha\) be an isomorphism with the commutative diagram: + +\[(1) \quad \begin{array}{ccc} M & \xrightarrow{\alpha} & M \otimes L^\infty(G) \\ \alpha \downarrow & & \downarrow \alpha \otimes \iota \\ M \otimes L^\infty(G) & \xrightarrow{\iota \otimes \delta} & M \otimes L^\infty(G) \otimes L^\infty(G), \end{array}\] + +where \((\delta f)(s, t) \equiv f(st)\) for \(f \in L^\infty(G)\) . + +For the right regular representation \(\lambda_G\) of \(G\) on \(L^2(G)\) , i.e., + +\[(\lambda_G(s)f)(t) \equiv f(ts), \quad f \in L^2(G), s, t \in G,\] + +let \(R(G)\) denote the von Neumann algebra generated by \(\lambda_G(G)\) . Let \(\gamma\) denote the isomorphism of \(R(G)\) into \(R(G) \otimes R(G)\) defined by + +AMS (MOS) subject classifications (1970). Primary 46L10. + +Key words and phrases. von Neumann algebra, crossed product, duality. + +Copyright © 1975, American Mathematical Society + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/headers_footers/e83afed6342a82de99744c654ba0d1158124bfa8_page_1_pg1_repeat1.md b/outputs/headers_footers/e83afed6342a82de99744c654ba0d1158124bfa8_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..31705217d454e2edb61f11f96ffc034553d49fd6 --- /dev/null +++ b/outputs/headers_footers/e83afed6342a82de99744c654ba0d1158124bfa8_page_1_pg1_repeat1.md @@ -0,0 +1,5 @@ +## O23 SURGICAL REPAIR OF PARASTOMAL BULGING - A REGISTER-BASED STUDY + +Marianne Krogsgaard1, Ismail Gögenur2, Frederik Helgstrand2, Rune Martens Andersen3, Anne Kjærgaard Danielsen4, Anders Vinther4, Tobias Klausen4, Jens Hillingsø5, Bo Marcel Christensen5, Thordis Thomsen4 1Zealand University Hospital, Koege, Department of Surgery, Koege, Denmark, 2Zealand University Hospital, Department of Surgery, Koege, Denmark, 3Næstved-Slagelse-Ringsted Region Zealand, The Research Unit Progrez, Denmark, 4Herlev and Gentofte Hospital, Denmark, 5Rigshospitalet, Denmark + +Aim: To examine the incidence of primary and recurrent repair and types of repair performed in patients with parastomal bulging. Material and Methods: We linked prospectively collected data on parastomal bulging from the Danish Stoma Database to surgical data on repair of parastomal bulging from the Danish National Patient Register. Survival statistics provided cumulative incidences and time until primary and recurrent repair Results: Of 1016 patients, registered from 2010-2017 with a permanent stoma and a parastomal bulge, 180 (18%) underwent surgical repair. The cumulative incidence of a primary repair was 9% (95% CI [8%; 11%]) within 1 year and 19% (95% CI [17%; 22%]) within 5 years after the occurrence of a parastomal bulge. For colostomies and ileostomies, we found similar probability of undergoing primary repair. For recurrent repair, the 5-year cumulative incidence was 5% (95% CI [3%; 7%]). The probability of undergoing further recurrent repair was 33% (95% CI [21%; 46%]) within 5 years. For primary repair, open or laparoscopic repair with mesh (43%) and stoma revision (39%) were performed almost equally frequent. Stoma revision and repair with mesh could precede and follow one another as primary and recurrent repair. Stoma reversal was performed in 17% of patients. Conclusions: Our data offered a new and comprehensive view of the course of surgical treatment of parastomal bulging. Five years after the occurrence of a parastomal bulge the estimated probability of undergoing a repair was 19%. The probability of undergoing recurrent repair was high and stoma reversal more common than expected. diff --git a/outputs/headers_footers/e99fc5946d09541cc7d1b887c328cfe15740cdb9_page_1_pg1_repeat1.md b/outputs/headers_footers/e99fc5946d09541cc7d1b887c328cfe15740cdb9_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6b78a9e6e1b0cffb581605b0253a0f0770d5b790 --- /dev/null +++ b/outputs/headers_footers/e99fc5946d09541cc7d1b887c328cfe15740cdb9_page_1_pg1_repeat1.md @@ -0,0 +1,18 @@ +![](figure) + +## Disertační práce + +# Didaktika animované tvorby s využitím digitálních technologií + +## Didactics of Animated Art Using Digital Technologies + +| Autor: | Mgr. MgA. Pavel Trnka | +| --- | --- | +| Studijní program: | P8206 Výtvarná umění | +| Studijní obor: | 8206V102 Multimédia a design | +| Školitel: | Prof. Ondrej Slivka ArtD. | +| Oponenti: | Prof. Mgr. Ľudovít Labík, ArtD. (oponent) | + +Doc. Vladimír Malík, ArtD (oponent) + +## Zlín, duben 2018 diff --git a/outputs/headers_footers/e9e4de7ee54054e15f3a2d31c4c1a39dae0a8a4c_page_1_pg1_repeat1.md b/outputs/headers_footers/e9e4de7ee54054e15f3a2d31c4c1a39dae0a8a4c_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4a55df87af605f81fdb72a685a60ee681730a7c9 --- /dev/null +++ b/outputs/headers_footers/e9e4de7ee54054e15f3a2d31c4c1a39dae0a8a4c_page_1_pg1_repeat1.md @@ -0,0 +1,29 @@ +# A Closer Look at Credit Ratings for CDOs + +### Rama CONT + +### & + +### Amal \(\text{MOUSSA}^{*}\) + +## Dept of Statistics & Center for Financial Engineering Columbia University, New York + +& + +## Laboratoire de Probabiltés et Mod`eles Aléatoires, CNRS (Paris) + +#### Abstract + +Credit ratings assigned by rating agencies to structured credit products have played an important role in the development of the structured credit market, which has been cast into the limelight by the recent credit crisis. This study aims at clarifying some misconceptions related to CDO ratings, their interpretation and their use. + +We first describe the rating approaches used by major agencies for CDOs and other structured credit products. Most rating agencies have been using static factor models which are slight variations on the Gaussian copula model allowing for intersector and intrasector correlations. Using this framework, we explore several issues related to CDO ratings. Our findings can be summarized as follows: + +- Given the leveraged nature of CDOs, the downgrade risk of a CDO tranche can be quite different from a bond with same initial rating. Therefore, a simple labeling via default probability or expected loss does not discriminate sufficiently their downgrade risk. + +- CDO tranche ratings require assumptions on the dependence structure of the default times and are thus exposed to model risk. We explore this model risk for CDO and CDO-squared tranches in a multisector factor model. + +- The interaction between the rating threshold and the structuring procedure can cause new issues to have tranches structured ”at the limit” of rating categories and thus a high probability of downgrading. + +- Migration probabilities for tranches with similar rating can vary from structure to structure even for the same underlying debt portfolio: two tranches with the same rating can have completely different transition probabilities. + +∗The paper will be presented by Amal Moussa. Email: am2810@columbia.edu diff --git a/outputs/headers_footers/eac8e314c175b009ea2074f1bbef6922ca9d736b_page_1_pg1_repeat1.md b/outputs/headers_footers/eac8e314c175b009ea2074f1bbef6922ca9d736b_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..be4810cef2060595a9ecf941b0cfdb021167ee88 --- /dev/null +++ b/outputs/headers_footers/eac8e314c175b009ea2074f1bbef6922ca9d736b_page_1_pg1_repeat1.md @@ -0,0 +1,59 @@ +# ON HARDING AVE + +![](figure) + +# Ike’s Diner Now Open on Harding + +![](figure) + +![](figure) + +Joining the list of popular culinary establishments in the downtown district is Ike’s Diner, located at 9476 Harding Avenue. The Diner was created by a partnership between long-time restaurateur Samir Elnomany and Kosher Chef Yossi Horowitz. The diner serves breakfast all day, pastas, salads, pizzas, fish, sandwiches, ice cream by the scoop and delicious iced coffees. Ike’s Diner is serving from 7:30 a.m. – 11 p.m. every day except Saturday. Home deliveries are available. For more information, call (305) 397-8559. + +##### Other businesses scheduled to open soon + +In the near future look for these news businesses in the downtown district: + +- Starbucks - 9560 Harding (late August opening) + +- Harvest Moon - 9427 Harding + +- Tiberius - 9472 Harding + +- Yogurt Spot – 9519 Harding + +#### Business Improvement District in Planning + +On July 17th a public meeting was held to discuss the possibility of creating a Business Improvement District (BID) for Downtown Surfside. Redevelopment Management Associates (RMA) presented information on how BIDs work and described possible BID programs for Downtown Surfside. Similar to a Homeowners Association, but for commercial properties, a BID formalizes a process for property and business owners to work together to improve a commercial district. Property and business owners will finalize plans for a BID and bring the project for approval by the Town Commission. For more information, contact Duncan Tavares - Tourism, Economic Development & Community Services Director - at 305-864-0722. + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Isaac Bashevis Singer Street Sign ✓ Unveiled + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +(L-R) Special Projects Director Randy Stokes, Commissioner Marta Olchyk and Town Manager Mike Crotty join residents at the unveiling. + +Isaac Bashevis Singer, a 1978 winner of the Nobel Prize for literature and a leading figure in Yiddish literature, was a resident of the Town in the 1980s. Now the Surfside street named in his honor has new, more prominent signage. A brief ceremony attended by residents and Town officials marked the unveiling of the signs on 95th Street. In addition to the Nobel prize, Singer also won two National Book Awards for his novels and short story collections. He died on July 24, 1991. + +# Parking Lot Renovations Planned + +The Town Commission has approved renovations and new landscaping for two major parking lots in the downtown Surfside district. The first is the Abbott lot between 95th and 96th Streets (west of Harding Avenue behind the CVS and Flanigan’s). The other is the 94th Street lot (on the southeast corner of 94th and Harding Avenue). Contractors Lynx Construction and Luke’s Landscaping will be working with Public Works to complete the renovation. The project is scheduled to begin before the end of August. + +# Streetscape Improvement Takes Next Step + +The plans for the Harding Avenue Streetscape are now being reviewed by the Florida Department of Transportation, since Harding Avenue is a state-owned street. The Town is planning to start the project as soon as it is approved by the Florida DOT. Designed by the firms of Stantac and Rosenberg Gradner, the Harding Avenue Streetscape plan will transform the downtown area with Medjool palms, colorful tropical shrubs and pocket parks with benches, pavers and street crossings. diff --git a/outputs/headers_footers/ec568c2d2cf0bc30d4729892f190f588e857bb57_page_12_pg1_repeat1.md b/outputs/headers_footers/ec568c2d2cf0bc30d4729892f190f588e857bb57_page_12_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..139d37ac6ea63fa6c15c5e7cac241c285396b899 --- /dev/null +++ b/outputs/headers_footers/ec568c2d2cf0bc30d4729892f190f588e857bb57_page_12_pg1_repeat1.md @@ -0,0 +1,24 @@ +Table 2. Threshold voltage assignment of the three proposed registers. + +| | Register 1 | Register 2 | Register 3 | +| --- | --- | --- | --- | +| M1 | low-Vth | low-Vth | low-Vth | +| M2 | low-Vth | high-Vth | low-Vth | +| M3 | low-Vth | high-Vth | low-Vth | +| M4 | low-Vth | low-Vth | low-Vth | +| M7 | low-Vth | low-Vth | high-Vth | +| M8 | low-Vth | low-Vth | high-Vth | +| M9 | low-Vth | low-Vth | high-Vth | +| M10 | low-Vth | low-Vth | high-Vth | +| M13 | high-Vth | low-Vth | low-Vth | +| M14 | high-Vth | low-Vth | low-Vth | +| M17 | high-Vth | low-Vth | low-Vth | +| M18 | high-Vth | low-Vth | low-Vth | +| M19 | high-Vth | low-Vth | low-Vth | +| M20 | high-Vth | low-Vth | low-Vth | +| M21 | high-Vth | low-Vth | low-Vth | +| M22 | high-Vth | low-Vth | low-Vth | + +### 4.3. Reduction in the Leakage Current + +The amount of reduction in the leakage current achieved by utilizing the proposed three registers is evaluated in this section. Four CMOS technology generations, 45 nm, 32 nm, 22 nm, and 16 nm, are considered using a predictive technology model [28,29]. The register illustrated in Figure 8 is simulated for each technology node where the \(W/L\) ratios of the transistors are maintained constant. The leakage current drawn from the power supply is evaluated for the three registers and the results are compared with the leakage current of the original register where only low-Vth transistors are used. The results are illustrated in Figure 9. Note that for the first register, the state of the clock signal does not change the results since all of the high-Vth transistors are within the slave latch. For the second and third registers, however, high-Vth transistors exist within the tristate inverters. The state of the clock signal is therefore important in evaluating the results. For example, for the second register, clock signal should be at VSS to guarantee that the initial tristate inverter is not in the high impedance state. Similarly, for the third register, clock signal should be at VDD so that the second tristate inverter located along the feedback path is not in the high impedance state. The leakage current of the original register is therefore compared with the first two registers and third register when the clock signal is, respectively, at VSS and VDD. The leakage current increases with technology, exhibiting a large jump in the 16 nm node. A significant amount of reduction in the leakage current, 79% on average, is achieved by the first register since the number of high-Vth transistors is higher, as listed in Table 2. The second register also achieves a considerable amount of reduction in the leakage current, 13% on average and higher below 32 nm diff --git a/outputs/headers_footers/ed107236f9863d65c41f29cd8e8091ba76cc61d8_page_2_pg1_repeat1.md b/outputs/headers_footers/ed107236f9863d65c41f29cd8e8091ba76cc61d8_page_2_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c9932e3208c8981f93cc5aa256cface451523076 --- /dev/null +++ b/outputs/headers_footers/ed107236f9863d65c41f29cd8e8091ba76cc61d8_page_2_pg1_repeat1.md @@ -0,0 +1,11 @@ +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Flow cytometric analysis of human ICAM3(CD50) expression on human peripheral blood lymphocytes. Cells were stained with purified anti-Human ICAM3(CD50), then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of viable lymphocytes. + +Flow cytometry was performed on a BD FACSCalibur flow cytometry system. Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols. diff --git a/outputs/headers_footers/ee8471bc3c47112296cb3d168b4ea4910020da72_page_40_pg1_repeat1.md b/outputs/headers_footers/ee8471bc3c47112296cb3d168b4ea4910020da72_page_40_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2ae8b0301386e576d6dd92af07cc0a09df8637b5 --- /dev/null +++ b/outputs/headers_footers/ee8471bc3c47112296cb3d168b4ea4910020da72_page_40_pg1_repeat1.md @@ -0,0 +1,41 @@ +special education teachers. Two special education teachers were selected for interview from the + +San Francisco Bay area. The following is a summary of the questions, responses and discussions + +obtained from the interview with the special and education teachers: + +## Special Education Teachers + +## How would you describe your opportunities to work with your students outside of the main classroom? + +Both teachers states that they spend 60% or more of their time outside of the general + +education classroom. During this time they either teach special day classes such as math or + +language arts or work with small groups of students on content areas of need as set out in their + +IEP. These time allotments are dictated and controlled by the IEP requirements of their students. + +One of the other main tasks they undertake is testing IEP goals through, among other things, the + +progress monitoring of students. During these progress monitoring sessions these students are + +tested one- on -one through informal assessments. The time periods that the special education + +teachers are working with the students that are being “pulled out” range from 15 minutes to an + +hour. + +The teachers also use IPads in their classrooms to play academic games. When the + +teachers are working with the students on their IEP goals they are, most of the time, using their + +own special education curriculum, which is either phonics, based or touch math. One of the two + +teachers sent a note to all of the general education teachers saying that she would be happy to + +work with the students sent to her on all assignments and projects that were being worked on in + +the general education classroom. However the other teacher states that the only time she works + +on general education assignments is when there is a test or quiz that needs to be finished. diff --git a/outputs/headers_footers/ee9d425ceb208aed7d1e2220145e315487706d09_page_1_pg1_repeat1.md b/outputs/headers_footers/ee9d425ceb208aed7d1e2220145e315487706d09_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..802b8d3b2e86b4f4ec42355990216f67fe3f40d0 --- /dev/null +++ b/outputs/headers_footers/ee9d425ceb208aed7d1e2220145e315487706d09_page_1_pg1_repeat1.md @@ -0,0 +1,27 @@ +![](figure) + +![](figure) + +# UvA-DARE (Digital Academic Repository) + +### Lattice models with N=2 supersymmetry + +Fendley, P.; Schoutens, K.; de Boer, J. + +#### Publication date 2003 + +## Published in Physical Review Letters + +#### Link to publication + +## Citation for published version (APA): + +Fendley, P., Schoutens, K., & de Boer, J. (2003). Lattice models with N=2 supersymmetry. Physical Review Letters, 90, 120402. + +## General rights + +It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). + +## Disclaimer/Complaints regulations + +If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. diff --git a/outputs/headers_footers/ef5e1f5960b9f865c8257f9ce4ff152a13a2559c_page_26_pg1_repeat1.md b/outputs/headers_footers/ef5e1f5960b9f865c8257f9ce4ff152a13a2559c_page_26_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..dd4191a73767fba10d44988403121e23225f5a5c --- /dev/null +++ b/outputs/headers_footers/ef5e1f5960b9f865c8257f9ce4ff152a13a2559c_page_26_pg1_repeat1.md @@ -0,0 +1,37 @@ +Dressen M. & Flocco G., eds. (2012). Temps professionnels éclatés, TIC et urgences, La Nouvelle Revue du travail, 1(1) [en ligne]. + +Engeström Y., Puonti A., & Seppänen L. (2003). Spatial and Temporal Expansion of the Object as a Challenge for Reorganizing Work, in D. Nicolini, S. Gherardi et D. Yanow (eds.). Knowing in Organizations, Armonk, M.E. Sharpe, 150-186. + +Gherardi S. & Nicolini D. (2003). To Transfer is to Transform : The Circulation of Safety Knowledge, in D. Nicolini, S. Gherardi et D. Yanow (eds.), Knowing in Organizations, Armonk, M.E. Sharpe, 204-224. + +Gold R. (1952). Janitors versus Tenants: A Status-Income Dilemma, American Journal of Sociology, 57 (5), 486-493. + +Gold R. L. (1964). In the Basement. The Aparment-Building Janitor, in P. L. Berger (ed.), The Human Shape of Work. Studies in the Sociology of Occupations, New York, Macmillan, 1-49. + +Hood J. C. (1988). From Night to Day: Timing and the Management of Custodial Work, Journal of Contemporary Ethnography, 17 (1), 96-116 (reproduit in D. Harper & H. M. Lawson, eds., The Cultural Study of Work, Oxford U.K., Roman and Littlefield, 2003, 246-260). + +Jarzabkowski P., Balogun J., & Seidl D. (2007). Strategizing: The challenge of a practice perspective, Human Relations, 60 (1), 5-27. + +Laé J.-F. (1996). La main courante en HLM et l’événement, Sociologie et sociétés, t. XXVIII, 177-188. + +Latour B. (2011). “What’s the story ?” Organizing as a mode of existence, in J. H. Passoth, B. Peuker & M. Schillmeier, eds., Agency without Actors?, London, Routledge. + +Marchal H. (2006). Le petit monde des gardiens-concierges. Un métier au cœur de la vie HLM, Paris, L’Harmattan, 213 p. + +Orlikowski W. J. & Yates J. (2002). It’s about Time: Temporal Structuring in Organizations, Organization Science, 13 (6), 684-700. + +Raveyre M. & Ughetto P. (2006). “On est toujours dans l’urgence” : surcroît ou défaut d’organisation dans le sentiment d’intensification du travail ?, in P. Askenazy, D. Cartron, F. de Coninck, M. Gollac (eds.). Organisation et intensité du travail, Toulouse, Octarès, 121-128. + +Reynaud J.-D. (1988). Les régulations dans les organisations : régulation de contrôle et régulation autonome, Revue française de sociologie, 29 (1), 5-18. + +Sewell W. H., Jr. (1992). A Theory of Structure : Duality, Agency, and Transformation, American Journal of Sociology, 98 (1), 1-29. + +Star S. L. & Strauss A. (1999). Layers of Silence, Arenas of Voice: The Ecology of Visible and Invisible Work, Computer Supported Cooperative Work, 8, 9-30. + +Taylor J. R. & Robichaud D. (2004). Finding the Organization in the Communication: Discourse as Action and Sensemaking, Organization, 11 (3), 395-413. + +Ughetto P. (2011a). Les organismes HLM en lutte contre les dépôts intempestifs d’encombrants et les locataires qui dégradent. Une qualité de service impossible ?, Annales des Mines. Gérer et comprendre (105), 50-58. + +Ughetto P. (2011b). Gardien d’immeuble : sentir et ressentir, Communications, (89), 89-100. Weick K. E. (1995). Sensemaking in Organizations, Thousand Oaks, Sage, 224 p. + +Pascal UGHETTO est sociologue, professeur à l’Université Paris-Est Marne-la-Vallée, où il réalise ses recherches au sein du LATTS. Ses recherches portent sur les transformations contemporaines de l’activité de travail, la montée des exigences adressées aux salariés dans le cadre des changements technologiques, organisationnels ou managériaux et la façon dont l’organisation soutient ou complique la réalisation de l’activité. Il a mené des enquêtes dans divers secteurs, entreprises et administrations : grande distribution, hôpital, habitat social, musées, ministère des Finances, juridictions de proximité, La Poste. diff --git a/outputs/headers_footers/f00ddca24b02c1e919e418f52f7f43b851b43bd6_page_5_pg1_repeat1.md b/outputs/headers_footers/f00ddca24b02c1e919e418f52f7f43b851b43bd6_page_5_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7221902d586210225df21e97acea69358bfb1df1 --- /dev/null +++ b/outputs/headers_footers/f00ddca24b02c1e919e418f52f7f43b851b43bd6_page_5_pg1_repeat1.md @@ -0,0 +1,127 @@ +# SMi21: DCmind-SOFT VEREINFACHTE PROGRAMMIERUNG + +#### www.crouzet-motors.de + +![](figure) + +![](figure) + +![](figure) + +### EINFACHE UND INTUITIVE SOFTWARE + +Verfügbar in mehreren Sprachen, mit vielfältigen Einsatzmöglichkeiten in allen Leistungsbereichen. + +## 2 PROGRAMMIERMODI + +› Anwendungsansatz: Sie wählen eine Anwendungsvorlage aus und stellen nur die für Ihre Anwendung spezifischen Parameter ein. Diese Programme arbeiten mit voreingestellten Experten-Programmen. Durch Aufrufen des jeweiligen Experten-Programms können Sie die Parameter feineinstellen. + +› Expertenansatz: Für Systemprogramme und Einstellungen zur Automatisierung, die einen breiten Parameterbereich abdecken. + +Diese Anwendungs- und Expertenprogramme sind auch als “program manufacturer” in CANopen verfügbar. + +### DCMIND SOFT & DCMIND SOFT + CANOPEN + +Auf unserer Webseite unter www.crouzet-motors.de zum Download verfügbar oder auf USB-Stick im „Einsteiger-Kit“ lieferbar. + +# ANWENDUNGEN + +Vielfältige Anwendungsbereiche, in denen Positionsregelung, Bewegungswiederholung und Genauigkeit unerlässlich sind. + +↑ + +![](figure) + +Schrittbetrieb, Schuberkennung und proportionale Kraftanpassung + +![](figure) + +![](figure) + +Zyklischer Betrieb, Anpassung von Drehzahl und Kräften. Umschaltung auf Sicherheitsmodus im Fehlerfall + +![](figure) + +![](figure) + +Kombination aus mehreren Motoren, Betrieb möglich ohne SPS, einfache Montage + +![](figure) + +![](figure) + +Menü „Anwendung“ + +![](figure) + +![](figure) + +Menü „Experte“ + +![](figure) + +![](figure) + +Modus „Parameterdefinition“ + +![](figure) + +![](figure) + +Betrieb mit 12 V Batterie, niedriger Stromverbrauch + +### LEISTUNGSMERKMALE + +## 3 Sprachen + +Englisch, Französisch,Deutsch. (Englisch für CANopen) + +##### Betriebssystem: + +XP Family Edition, XP Pro, Vista, Windows 7. + +##### Anwendungsprogramme: + +Ventil, Förderband, Zange, Formatverstellung, usw. + +##### Experten-Programme: + +Position, Drehzahl, Drehmoment mit digitalen oder analogen Eingängen. + +## › Zahlreiche Programme für maximale Flexibilität: + +- 65.000 proportionale Positionen, wählbar über zwei Eingänge mit 0/10 V + +- 30 unabhängige Positionen über digitale Codierung + +- Mehrere Ausgangsoptionen zur bedarfsgerechten Konfiguration wählbar + +- Möglichkeit, die Eingänge umzukehren, Analogeingänge mit 0/10 V oder PWM zu verwenden oder ihre Endpositionen einzustellen + +- Möglichkeit zur Anpassung der PID-Parameter der Regelung für komplexe Anwendungen + +- Automatische Erkennung der Referenzposition für die Positionierung (Homing-Funktion) + +› Erstellung von speziellen Programmen auf Anfrage, vereinfachte Firmwareaktualisierung durch Bootloader-Funktion + +› Laden von Programmen per USB-Verbindung + +› Weitere Programme in Vorbereitung, besuchen Sie unsere Website! + +### ANWENDUNGSBEISPIELE + +Formatanpassung, automatische Zuführung, Synchronisation, Durchflussregelung, präzise Dosierung. + +![](figure) + +![](figure) + +↑ + +S-Kurven-Vorsteuerung und Betrieb mit 12 V Backup-Batterie + +![](figure) + +![](figure) + +Drehzahl-Vorsteuerung diff --git a/outputs/headers_footers/f2cca1cd338edf4616f1bfe3f4b0ec7ea0e7ec67_page_3_pg1_repeat1.md b/outputs/headers_footers/f2cca1cd338edf4616f1bfe3f4b0ec7ea0e7ec67_page_3_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a07240184b417fb2c15556daf9857d3a09715424 --- /dev/null +++ b/outputs/headers_footers/f2cca1cd338edf4616f1bfe3f4b0ec7ea0e7ec67_page_3_pg1_repeat1.md @@ -0,0 +1,31 @@ +![](figure) + +![](figure) + +FIG. 1. Excitation scheme for LIF-dip spectroscopy in xenon. + +# II. EXPERIMENTAL INVESTIGATIONS + +In this section we present our experimental investigations on Stark effects of xenon ns and nd levels. First, the experimental arrangement is described in Sec. II A. Next, the results of the measurements are presented in Sec. II B. + +# A. Experimental arrangement + +The experimental arrangement consisted of a laser system for the excitation of xenon atoms to Rydberg levels, an electrode arrangement for the application of electric fields, and a detection system to monitor fluorescence light. Stark effects in xenon were measured by probing high-lying Rydberg states by LIF-dip spectroscopy. We used a \(2+1-\)photon excitation scheme, shown in Fig. 1, which was similar to that used by Ebata et al. \(18\) for investigations in NO and Czarnetzki et al. \(14\) for atomic hydrogen. First, ground-state xenon atoms were excited to the \(6p1/2_{0}\) level in a two-photon transition at 249.629 nm. Subsequently, fluorescence light with a wavelength of 828.2 nm could be observed as a result of decay to the \(6s3/2_{1}\) state. A second laser was tuned to probe the transition between the intermediate \(6p1/2_{0}\) level and high-lying Rydberg ns and nd states. A resonance for such a transition was detected as a decrease of the fluorescence intensity, because part of the \(6p1/2_{0}\) level population was transferred to the Rydberg state. Therefore, when scanning the second laser and monitoring the fluorescence intensity, a transition to a Rydberg state was detected as a dip in the spectrum. The two lasers necessary for the excitation were both tun-able dye lasers, pumped by the same pulsed neodymium-doped yttrium aluminum garnet \(Nd:YAG\) laser. The first dye laser was pumped by the third harmonic of the Nd:YAG laser and operated at 499.258 nm. This light was subsequently frequency doubled by a beta barium borate \(BBO\) crystal to create 249.629 nm photons for the two-photon transition. The second dye laser was pumped by the second harmonic output of the same Nd:YAG laser and operated at wavelengths between 580 and 630 nm. + +![](figure) + +![](figure) + +FIG. 2. Schematic diagram of the electrical arrangement for creating short voltage pulses. The high-voltage transistor switch Behlke Electronic GmbH could be triggered externally for synchronization purposes. The electrodes were mounted inside a vacuum chamber, creating a gap of 3 mm. + +Both beams were sent to a vacuum chamber containing an electrode arrangement. The two beams were parallel to the electrode surfaces and crossed each other in between the electrodes. The energies of both lasers were reduced to a few hundred microjoules to avoid initiating a discharge and disturbing the applied electric field. The fluorescence light was detected perpendicular to the laser beams by an intensified charge-coupled device \(ICCD\) camera. A lens system and an interference filter imaged the fluorescence light onto the ICCD camera, detecting only 828.2 nm light. We applied a pulsed electric field to parallel plate electrodes, separated by 3 mm, in xenon gas at 50 Pa. The field was pulsed to prevent the formation of a discharge for voltages above the breakdown voltage of the system. Using the electrical scheme shown in Fig. 2, we could apply voltage pulses with a full width at half maximum of about 50 ns and an amplitude of up to 1.5 kV. In this way, the electric field in the gap was controllable and uniform. Finally, the lasers, the ICCD camera and the voltage pulse were synchronized with a delay generator. + +# B. Experimental results + +## 1. Stark effects for nd levels + +We investigated Stark effects for nd\(3/2_{1}\) levels with principal quantum numbers n= 12–15 and n= 18. Figure 3 shows fluorescence-dip spectra for the transition to \(15d3/2_{1}\) in different electric fields. It is clear that the dip at 586.51 nm, corresponding to the \(15d3/2_{1}\) level, moves to longer wavelengths for increasing electric fields. Additionally, for an electric field of 2100 V/cm, we observe extra dips at wavelengths 586.40 and 586.28 nm. These dips correspond to transitions to 13f levels which are forbidden without an electric field, but become allowed when they are mixed with other levels in high electric fields. The shifts of nd\(3/2_{1}\) levels in electric field for principal quantum numbers n= 12–15, and n= 18 are shown in Fig. 4. For applied electric fields between 0 and 4000 V/cm, we measured Stark shifts of up to 4.8 cm−1. The measurements show that the observed shift is higher for larger principal quantum numbers, as expected. + +## 2. Stark effects for ns levels + +The shifts of ns\(3/2_{1}\) levels in electric fields for principal quantum numbers n= 14–16 are shown in Fig. 5. Applying diff --git a/outputs/headers_footers/f3dc69b44af3519770366dc8e0be86ab6f0bd30f_page_4_pg1_repeat1.md b/outputs/headers_footers/f3dc69b44af3519770366dc8e0be86ab6f0bd30f_page_4_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d506a7b52c26882855b54ea0ef4602a753af2500 --- /dev/null +++ b/outputs/headers_footers/f3dc69b44af3519770366dc8e0be86ab6f0bd30f_page_4_pg1_repeat1.md @@ -0,0 +1,63 @@ +## • Balancing resistance and infection tolerance through metabolic means PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA + +Chambers, M. C., Schneider, D. S. 2012; 109 (35): 13886-13887 + +- Immunity in Society: Diverse Solutions to Common Problems PLOS BIOLOGY + +Babayan, S. A., Schneider, D. S. 2012; 10 (4) + +- Disease Tolerance as a Defense Strategy SCIENCE + +Medzhitov, R., Schneider, D. S., Soares, M. P. 2012; 335 (6071): 936-941 + +- Pioneering immunology: insect style CURRENT OPINION IN IMMUNOLOGY + +Chambers, M. C., Schneider, D. S. 2012; 24 (1): 10-14 + +- Tolerance of Infections ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 + +Ayres, J. S., Schneider, D. S. 2012; 30: 271-294 + +## • Drosophila immunity research on the move. Fly + +Eleftherianos, I., Schneider, D. 2011; 5 (3): 247-254 + +## • Reciprocal Analysis of Francisella novicida Infections of a Drosophila melanogaster Model Reveal Host-Pathogen Conflicts Mediated by Reactive Oxygen and imd-Regulated Innate Immune Response PLOS PATHOGENS + +Moule, M. G., Monack, D. M., Schneider, D. S. 2010; 6 (8) + +## • Relating immune and stress responses to infection resistance and tolerance BRAIN BEHAVIOR AND IMMUNITY + +Schneider, D. 2010; 24 (2): 193-193 + +## • The Drosophila TNF Ortholog Eiger Is Required in the Fat Body for a Robust Immune Response JOURNAL OF INNATE IMMUNITY + +Mabery, E. M., Schneider, D. S. 2010; 2 (4): 371-378 + +- The Imd Pathway Is Involved in Antiviral Immune Responses in Drosophila PLOS ONE + +Costa, A., Jan, E., Sarnow, P., Schneider, D. 2009; 4 (10) + +## • A Signaling Protease Required for Melanization in Drosophila Affects Resistance and Tolerance of Infections PLOS BIOLOGY + +Ayres, J. S., Schneider, D. S. + +2008; 6 (12): 2764-2773 + +## • MICROBIOLOGY Rogue Insect Immunity SCIENCE + +Schneider, D. S., Chambers, M. C. 2008; 322 (5905): 1199-1200 + +- Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases NATURE REVIEWS IMMUNOLOGY + +Schneider, D. S., Ayres, J. S. 2008; 8 (11): 889-895 + +## • Use of a Drosophila Model to Identify Genes Regulating Plasmodium Growth in the Mosquito GENETICS + +Brandt, S. M., Jaramillo-Gutierrez, G., Kumar, S., Barillas-Mury, C., Schneider, D. S. + +2008; 180 (3): 1671-1678 + +## • Models of infectious diseases in the fruit fly Drosophila melanogaster DISEASE MODELS & MECHANISMS + +Dionne, M. S., Schneider, D. S. diff --git a/outputs/headers_footers/f43191d17ea26f7058d5f9e5c6b3b4cc35bfaef2_page_63_pg1_repeat1.md b/outputs/headers_footers/f43191d17ea26f7058d5f9e5c6b3b4cc35bfaef2_page_63_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b89f4e3c88e5ba8839fea0941f42ce9f5da69a0c --- /dev/null +++ b/outputs/headers_footers/f43191d17ea26f7058d5f9e5c6b3b4cc35bfaef2_page_63_pg1_repeat1.md @@ -0,0 +1 @@ +## Årsregnskab for moderselskabet Coloplast A/S for 2007/08 diff --git a/outputs/headers_footers/f7469518fa45151f23fc0189cd9d284e52f694ce_page_1_pg1_repeat1.md b/outputs/headers_footers/f7469518fa45151f23fc0189cd9d284e52f694ce_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..414831b5fd9eb7dcbdb33461501d391bf7c86980 --- /dev/null +++ b/outputs/headers_footers/f7469518fa45151f23fc0189cd9d284e52f694ce_page_1_pg1_repeat1.md @@ -0,0 +1,193 @@ +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Papallona tigre Danaus chrysippus + +![](figure) + +![](figure) + +![](figure) + +Capgròs comú Carcharodus alceae + +Blanqueta de la col Pieris rapae + +Migradora dels cards Vanessa cardui + +![](figure) + +![](figure) + +Daurat fosc + +Moreneta + +| | Merlet ruderal | Thymelicus acteon | meridional | +| --- | --- | --- | --- | +| Blaveta | Pyrgus armoricanus | | Aricia cramera | + +![](figure) + +![](figure) + +![](figure) + +dels pèsols Lampides boeticus + +Blaveta estriada + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Aurora grogaLeptotes pirithous
Pòntia comunaAnthocharis euphenoidesMarbrada comuna
Euchloe crameriCoure comú
Lycaena phlaeas
+ +![](figure) + +![](figure) + +Pontia daplidice + +![](figure) + +Griseta mediterrània Polyommatus hispana + +![](figure) + +![](figure) + +![](figure) + +Barrinadora del gerani Cacyreus marshalli + +![](figure) + +Safranera de l’alfals Colias crocea + +Escac ferruginós Melanargia occitanica + +![](figure) + +Lleonada de garriga Coenonympha dorus + +![](figure) + +![](figure) + +![](figure) + +Blaveta comuna Polyommatus icarus + +Atalanta Vanessa atalanta + +Damer de la centàurea Melitaea phoebe + +Saltabardisses de solell Pyronia cecilia + +![](figure) + +![](figure) + +Blaveta de la farigola Pseudophilotes panoptes + +![](figure) + +Faune ziga-zaga Hipparchiafidia + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Marroneta de l’alzina Satyrium esculi + +Brocat variable Euphydryas aurinia Bruixa Brintesia circe + +![](figure) + +![](figure) + +Murri de la pimpinella Spialia sertorius + +![](figure) + +Arlequí Zerynthia rumina + +Turquesa mediterrània Glaucopsyche melanops + +Margenera comuna Lasiommata megera + +Blaveta del crespinell Scolitantides orion + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Damer dels + +| | conillets | | Saltabardisses cintada | +| --- | --- | --- | --- | +| Papallona de l’arboç | Melitaea deione | Angelet comú | Pyronia bathseba | +| Charaxes jasius | | Leptidea sinapis | | + +![](figure) + +![](figure) + +Verdeta d’ull blanc Callophrys rubi + +![](figure) + +Faune bru Hipparchia statilinus + +Verdeta d’ull ros Callophrys avis + +![](figure) + +![](figure) + +Blaveta de l’heura Celastrina argiolus + +![](figure) + +![](figure) + +![](figure) + +Nimfa mediterrània Limenitis reducta diff --git a/outputs/headers_footers/f7559ece0d7626472b9558a1a0573284d14ec44f_page_1_pg1_repeat1.md b/outputs/headers_footers/f7559ece0d7626472b9558a1a0573284d14ec44f_page_1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7ac40f924e2253b54164cace59ef740a6dd1fca6 --- /dev/null +++ b/outputs/headers_footers/f7559ece0d7626472b9558a1a0573284d14ec44f_page_1_pg1_repeat1.md @@ -0,0 +1,25 @@ +![](figure) + +![](figure) + +# The Use of Face Coverings in Construction during Coronavirus (COVID-19) + +## The Use of Face Coverings in Construction has always reflected the latest Government guidance. + +Whilst the Government’s Living with COVID-19 plan is clear that the pandemic is not yet over, the removal of the Working Safely during Coronavirus (Covid-19) guidance, along with the health and safety requirement for employers to explicitly consider COVID-19 in their risk assessments, from 1 April 2022 means that the Use of Face Coverings in Construction is no longer current and remains available as a reference document. + +## The Site Operating Procedures also remain available as a reference document. + +The Construction Leadership Council (CLC) has published this statement on the use of face coverings on construction sites in response to coronavirus to help provide a consistent approach across the industry. It is based on Government guidance in England and other restrictions and advice may apply in Scotland, Wales and Northern Ireland. + +## Definitions + +Face coverings are made from fabric or cloth and cover the mouth and nose to protect others, not the user, from infection. They are not PPE as they do not protect people from work-related hazards and are not made to a recognised standard. Surgical face masks are designed and manufactured to be used in medical settings to limit the spread of infection and they are resistant to droplets of fluids and splashes. Whilst they are made to a recognised standard, they are not considered to be PPE. Visors, which are usually worn to protect the face and eyes, are classed as PPE and protect the user, not others, against droplets carrying infection. Respirators, which are used extensively in construction activities, are classed as PPE and protect people from work-related hazards that cannot be eliminated or reduced in any other way. They should be specific to the hazard identified and provided free of charge by employers. + +## Current Government Position + +The Government suggests that face coverings should be worn in crowded and enclosed spaces where people may come into contact with others they don’t normally meet. Employers can choose to ask workers to wear a face covering, even though they are not legally required to, but need to consider reasonable adjustments for workers with disabilities, as well as other obligations to workers arising from legislation. Workers may also choose to wear a face covering where it is not legally required. The use of face coverings and/or PPE is not required in response to coronavirus whilst carrying out construction activities, and the Government guidance on Working safely during coronavirus (COVID-19) – Construction and other outdoor work states: Do not encourage the precautionary use of PPE to protect against COVID-19 unless in a clinical setting or responding to a suspected or confirmed case of COVID-19. + +## CLC Position + +Where workers on site are not required to wear Respiratory Protective Equipment (RPE) and their workplace is crowded and enclosed (which may include welfare and changing facilities, site offices, site meeting rooms or site transport) and they come into contact with others they do not normally meet, their employer should make face coverings available and they should be worn. diff --git a/outputs/headers_footers/f8a7ce21fc8ad066ed42ad6a91ccc99af25aa8a7_page_5_pg1_repeat1.md b/outputs/headers_footers/f8a7ce21fc8ad066ed42ad6a91ccc99af25aa8a7_page_5_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3e24f7a0648a6fc1c7254a66fdf7d578d4bcfea9 --- /dev/null +++ b/outputs/headers_footers/f8a7ce21fc8ad066ed42ad6a91ccc99af25aa8a7_page_5_pg1_repeat1.md @@ -0,0 +1,77 @@ +Our results suggest that PR status indeed provides very useful predictive information. The purpose of the study was to refine the evaluation of hormone receptor status by applying a quantified rather than dichotomized assessment. This approach has the disadvantage of rendering smaller subgroups and, consequently, loss of statistical power. Therefore, our results need to be confirmed in additional studies. However, they are promising in that a fractioned evaluation of immunohistochemical hormone receptor expression could easily be adopted and incorporated into clinical practice and clinical trials. + +# Acknowledgments + +We thank Elise Nilsson for excellent technical assistance. + +# References + +1. Early Breast Cancer Trialists’ Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet 1998;351:1451 ^ 67. + +2. Baum M, Budzar AU, Cuzick J, et al. Anastrozole + +alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet 2002;359: 3131 ^ 9. + +3. Goss PE, Ingle JN, Martino S, et al. A randomized trial + +of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med 2003;349:1793 ^ 802. + +4. Coombes RC, Hall E, Gibson LJ, et al. A randomized + +trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 2004;351:1081 ^ 92. + +5. Howell A, Cuzick J, Baum M, et al. Results of the + +ATAC (Arimidex,Tamoxifen, Alone, or in Combination) trial after completion of 5 years’adjuvant treatment for breast cancer. Lancet 2005;365:60 ^ 2. + +6. Reiner A, Spona J, Reiner G, et al. Estrogen receptor analysis on biopsies and fine-needle aspirates from human breast carcinoma. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies. Am J Pathol 1986;125:443 ^ 9. + +7. Allred DC, Bustmante MA, Daniel CO, Gaskill HV, Cruz AB, Jr. Immunocytochemical analysis of estrogen receptors in human breast carcinomas. Evaluation of 130 cases and review of the literature regarding concordance with biochemical assay and clinical relevance. Arch Surg 1990;125:107 ^ 13. + +8. Stierer M, Rosen H, Weber R, Hanak H, Spona J, Tuchler H. Immunohistochemical and biochemical measurement of estrogen and progesterone receptors + +in primary breast cancer. Correlation of histopathology and prognostic factors. Ann Surg 1993;218:13 ^ 21. + +9. Barnes DM, Harris WH, Smith P, Millis RR, Rubens RD. Immunohistochemical determination of oestrogen receptor: comparison of different methods of assessment of staining and correlation with clinical outcome of breast cancer patients. Br J Cancer 1996;74:1329 ^ 30. + +10. Molino A, Micciolo R, Turazza M, et al. Prognostic + +significance of estrogen receptors in 405 primary breast cancers: a comparison of immunohistochemical and biochemical methods. Breast Cancer Res Treat 1997;45:241 ^ 9. + +11. Harvey JM, Clark GM, Osborne CK, Allred DC. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 1999;17:1474 ^ 81. + +12. Mohsin SK, Weiss H, Havighurst T, et al. Progesterone receptor by immunohistochemistry and clinical outcome in breast cancer: a validation study. Mod Pathol 2004;17:1545 ^ 54. + +13. Fischer ER, Anderson S, Dean S, et al. Solving + +the dilemma of the immunohistochemical and other methods used for scoring estrogen receptor and progesterone receptor in patients with invasive breast carcinoma. Cancer 2005;103:164 ^ 73. + +14. Ravdin PM, Green S, Dorr TM, et al. Prognostic + +significance of progesterone receptor levels in estrogen receptor-positive patients with metastatic breast cancer treated with tamoxifen: results of a prospective Southwest Oncology Group study. J Clin Oncol 1992; 10:1284 ^ 91. + +15. Elledge RM, Green S, Pugh R, et al. Estrogen receptor (ER) and progesterone receptor (PgR), by ligand-binding assay compared with ER, PgR, and pS2, by immuno-histochemistry in predicting response to + +tamoxifen in metastatic breast cancer: a Southwest Oncology Group study. Int J Cancer 2000;89:111 ^ 7. + +16. Ferno« M, StMl O, Baldetorp B, et al. Result of two or + +five years of tamoxifen correlated to steroid receptor and S-phase levels. Breast Cancer Res Treat 2000; 59:69 ^ 76. + +17. Lamy PJ, Pujol P, Thezenas S, et al. Progesterone + +receptor quantification as a strong prognostic determinant in postmenopausal breast cancer women under tamoxifen therapy. Breast Cancer Res Treat 2002; 76:65 ^ 71. + +18. Bardou VJ, Arpino G, Elledge RM, et al. Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer databases. J Clin Oncol 2003;21:1973 ^ 9. + +19. Ryde¤n L, Jo«nsson PE, Chebil G, et al. Two years + +of adjuvant tamoxifen in premenopausal patients with breast cancer: a randomised, controlled trial with long-term follow-up. Eur J Cancer 2005;41: 256 ^ 64. + +20. Dowsett M, Cuzick J,Wale C, HowellT, Houghton J, Baum M. Retrospective analysis of time to recurrence in the ATAC trial according to hormone receptor status: an hypothesis-generating study. J Clin Oncol 2005;23:7512 ^ 7. + +21. Ryde¤n L, Chebil G, Dufmats M, et al. Adjuvant + +tamoxifen to premenopausal women reduces contra-lateral breast cancer. Results from a prospective randomized multicenter study with long-time follow-up. Breast Cancer ResTreat 2003;82:S30. + +22. Arpino G,Weiss H, Lee AV, et al. Estrogen receptor-positive, progesterone receptor-negative breast cancer: association with growth factor receptor expression and tamoxifen resistance. J Natl Cancer Inst 2005;97:1254 ^ 61. diff --git a/outputs/headers_footers/f90419e32818a50123aa4a0edf1b857230df37dc_page_7_pg1_repeat1.md b/outputs/headers_footers/f90419e32818a50123aa4a0edf1b857230df37dc_page_7_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..29c1d17f9e80885f842a361a93beecaf24d90ba4 --- /dev/null +++ b/outputs/headers_footers/f90419e32818a50123aa4a0edf1b857230df37dc_page_7_pg1_repeat1.md @@ -0,0 +1,99 @@ +## 6. OTROS TIPOS DE LÁSER + +En los últimos 20 años se han desarrollado más tipos de láser que los ya comentados, pero con escasa repercusión, como por ejemplo el láser de CO2 (22), el láser excimer (23) y el Erbium:YAG que tanto a nivel in vivo como in Vitro puede considerarse una alternativa prometedora al Ho:YAG. Sin embargo, no han tenido apenas relevancia y prácticamente se han abandonado los estudios salvo con este último. + +# CONCLUSIONES + +1. El uso del láser en el tratamiento de las estenosis uretrales es una alternativa válida, eficaz y segura, a la uretrotomía óptica; sin embargo por el momento no se ha demostrado que sea mejor que esta. + +2. La elección del tratamiento es cirujano dependiente, y ninguna técnica ha mostrado claramente ser superior a las demás. + +3. Se precisan estudios prospectivos a largo plazo, con un mayor número de pacientes y con mayor seguimiento + +4. La tecnología láser es cara y no esta disponible en todos los centros. + +# AGRADECIMIENTOS + +Fotos cortesía del Dr. Álvaro Serrano. + +# BIBLIOGRAFÍA y LECTURAS RECOMENDADAS (*lectura de interés y ** lectura fundamental) + +1. SACHSE, H.: “Zur Behandlung der Harnrohrenstriktur”. Fortschr. Med., 92: 12, 1974. + +- *2. GÓMEZ SANCHA, F.: “Fotovaporización prostática con láser KTP”. Silmi Moyano, A y Moreno Sierra, J. Endourología, Laparoscopia y Terapia mínimamente invasiva en Urología, Clínicas Urológicas de la Complutense, 11: 879, 2005. + +3. KAMAL, B.A.: “The use of the diode láser for treating uretrhal strictures”. BJU Int., 87: 831, 2001. + +- 4. GUAZZIERI, S. y cols.: “980-nm diode láser treatment for recurrent urethral strictures”. Eur. Urol., 39: 19, 2001. + +5. PERKASH, I.: “Ablation of urethral strictures using contact chisel crystal firing neodymium: YAG láser”. J. Urol., 157: 809, 1997. + +6. BULLOW, H.; BULLOW, V.; FROHMULLER, H.G.W.: “Transurethral láser urethrotomy in men: Preliminary report”. J. Urol., 121: 286, 1979. + +- 7. + +DOGRA, P.N.; ARON, M.; RAJEEV, T.P.: “Core tr-hough urethrotomy with the neodymium: YAG láser for posttraumatic obliterative strictures of the bulbomembranous urethra”. J. Urol., 161: 81, 1999. + +8. + +DOGRA, P.N.; NABI, G.: “Core trhough urethrotomy using the neodymium: YAG láser for obliterative urethral strictures after traumatic urethral disruption and/or distraction defects: Long term outcome”. J. Urol., 167: 543, 2002. + +9. + +DOGRA, P.N.; NABI, G.: “Nd: YAG láser core-through urethrotomy in obliterative posttraumatic urethral strictures in children”. Pediatr. Surg. Int., 19: 652, 2003. + +10. + +SMITH, J.A. Jr.: “Treatment of benign urethral strictures using a sapphire tipped neodymium: YAG láser”. J. Urol., 142: 1221,-1989. + +- 11. + +DOGRA, P.N.; ANSARI, M.S.; GUPTA, N.P. y cols.: “Holmium láser core through urethrotomy for traumatic obliterative strictures of urethra: Initial experience”. Urology, 64: 232, 2004. + +12. + +MATSUOKA, K.; INOUE, M.; IIDA, S. y cols.: “Endoscopic antegrade láser incision in the treatment of urethral stricture”. Urology, 60: 968, 2002. + +13. + +KAMP, S.; KNOLL, T.; OSMAN, M.M. y cols.: “Lowpower holmium: YAG láser urethrotomy for treatment of urethral strictures: functional outcome and quality of life”. J. Endourol., 20: 38, 2006. + +- 14. + +LAGERVELD, B.W.; LAGUNA, M.P.; DEBRUYNE, F.M. y cols.: “Holmium: YAG láser for treatment of strictures of vesicourethral anastomosis after radical prostatectomy”. J. Endourol., 19: 497, 2005. + +15. + +THOMAS, M.A.; ONG, A.M.; PINTO, P.A. y cols.: “Management of obliterated urinary segments using a láser fiber for access”. J. Urol., 169: 2284, 2003. + +16. + +FUTAO, S.; WENTONG, Z.; YAN, Z.: “Application of endoscopic Ho: YAG láser incision technique treating urethral strictures and urethral atresias in pediatric patients”. Pediatr. Surg. Int., 22: 514, 2006. + +- 17. + +SHANBERG, A.; BAGHDASSARIAN, R.; TANSEY, L. y cols.: “KTP 532 láser in treatment of urethral strictures”. Urology, 32: 517, 1988. + +18. + +TUREK, P.J.; MALLOY, T.R.; CENDROM, M. y cols.: “KTP-532 láser ablation of urethral strictures”. Urology, 40: 330, 1992. + +- 19. + +SCHMIDLING, F.; OSWALD, M.; ISELIN, C. y cols.: “Vaporization of urethral stenosis using the KTP 532 láser”. Ann. Urol., 31: 38, 1997. + +20. + +ADKINS, W.C.: “Argon láser treatment of uretrhal stricture and vesical neck contracture”. Láser Surg. Med., 8: 600, 1988. + +- *21. + +BECKER, H.C.; MILER, J.; NOSKE, H.D. y cols.: “Transurethral láser urethrotomy with the Argon láser: Experience with 900 urethrotomies in 450 patients from 1978 to 1993”. Urol. Int., 55: 150,1995. + +- *22. + +McNICHOLAS, T.A.; COLLES, J.; BROWN, S.G. y cols.: “Treatment of urethral strictures with a prototype CO2 láser endoscope”. Láser Surg. Med., 3: 427, 1988. + +23. + +BAUR, H.; SCHNEIDER, W.; ATTWEIN, J.E.: “Treatment of recurrent urethral strictures by photoablation with Excimer láser”. Baus Abstracts Book, pág. 118, 1992. diff --git a/outputs/headers_footers/f9440f15438ba36671183460e36dd9decbbb80dc_page_3_pg1_repeat1.md b/outputs/headers_footers/f9440f15438ba36671183460e36dd9decbbb80dc_page_3_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..37a41d9336b6da11631af440299b4c80bc012566 --- /dev/null +++ b/outputs/headers_footers/f9440f15438ba36671183460e36dd9decbbb80dc_page_3_pg1_repeat1.md @@ -0,0 +1,15 @@ +Table : Classification of two simulated s-TSH values from , individuals according to the bivariate distribution and the combination of RCVs and univariate reference limits. Classified as normal according to the bivariate distribution were the pairs of measurement within the central % of that distribution. Classified as normal according to the combination of RCVs and univariate reference limits were those pairs of measurements where the difference between them was within RCVs and both measurements were within the univariate reference range. + +| Combination of non-parametric | Bivariate distribution | Total | +| --- | --- | --- | +| RCVs and reference limits | | | +| | Normal Abnormal | | +| Normal | , | , | +| Abnormal | , , | , | +| Total | , , | , | + +and 0.960 (95 % CI 0.957 to 0.962) for those with x1 above the median. The graphical study of the s-sodium data is presented in a supplementary figure. The sensitivity of the combination of univariate reference limits and RCVs for identifying pairs of x1 and x2 lying outside the central 95 % of the bivariate distribution of s-sodium was 100 %. The specificity for identifying pairs of x1 and x2 lying inside the central 95 % of the bivariate distribution was 92.5 %. + +# Discussion + +If the physician does not know the patient’s setpoint value of s-TSH and wants to judge the clinical condition from s-TSH in two samples taken a time apart, we believe that the physician basically wants to assess whether the patient is healthy and stable. Then the two s-TSH values could be compared against the bivariate distribution in Figure 1, which represents a stable, euthyreot population. As clearly shown in Figure 1, the lines of the 2.5 and 97.5 percentile univariate reference limits in combination with the 2.5 and 97.5 percentile RCVs do not accurately delineate the central 95 % of the points of the bivariate distribution of x1 and x2. The space between the RCV lines contains 95 % of the points, as do the space between each set of reference limits, but the space between the RCVs and the reference limits is not congruent with the ellipse marking the central 95 % of the bivariate distribution. The RCV lines are approximately tangent to the ellipse marking the central 50 % of the distribution and cut through the other ellipses. Compared to the central 95 % of the bivariate distribution, the combination of univariate reference limits and RCVs had a fair specificity of 92.2 % but a lower sensitivity of 80.2 %. Without the assistance of univariate reference limits, the RCVs showed a particularly low sensitivity. Obviously, RCVs are not designed to detect healthiness, as the area between the limits of RCVs includes analyte concentrations from zero to infinity (Figure 1). These considerations are not limited to s-TSH; probability density contour plots for bivariate distributions are not straight lines for any analyte, as indicated in the Supplementary Figure. In the example of s-sodium, the diagnostic accuracy of the univariate reference limits and RCVs was considerably better than for s-TSH. Obviously, how well the combination of univariate reference limits and RCVs delineate the corresponding bivariate distribution must be studied for each analyte. Looking at the ellipses marking the various central proportions of the bivariate distribution and the line of equality (Figure 1), it is obvious that regression towards the mean does occur in this scenario. If the measured value in the first specimen (x1) is relatively low, the measured value in the second specimen (x2) is most likely to be higher, and vice versa. The median values of the difference x2 − x1 and the ratio x2/x1 for pairs with x1 below and above the median value of x1 showed the same phenomenon, as expected, because a difference in percent is equivalent to a ratio. We prefer ratios in this setting. Thus, the idea of RCVs as a constant fraction of the first measurement is flawed, a finding in accordance with a previous study [7]. We estimated the RCVs both parametrically and non-parametrically, to see whether the two methods gave different results. They did not; the two methods of estimation gave almost identical RCV lines. They were symmetrical about the equality line, and asymmetrical in the y direction. We simulated the s-TSH-values assuming a Gaussian distribution around the setpoints; still, the nonparametrically derived RCVs based on the simulated values were asymmetrical in the y direction. We believe our data set was theoretically sound. Data were derived from a Gaussian distribution truncated at ±3 standard deviation, and transformed to lognormally distributed data as coming from an euthyreot (healthy) population. Each data pair was generated from the same, individual setpoint value, so the data represented a stable population. All data pairs were generated with the same CVI of 17.9 % [4], thus the variance was homogeneous. The value of 3.4 % for CVA is the total CVA in our laboratory, estimated from quality control values over several months. Truncation at ±3 standard deviation when generating population set-point and individual values were done because those distributions are not really Gaussian (they do not include values from minus to plus infinity) and often values outside ±3 standard deviation are regarded as outliers. Note that this work deals with how the physician might interpret two s-TSH values from the same patient when the patient’s setpoint value is unknown. It has no relevance if the physician needs to judge a time series of three or more measured values of the same analyte. Neither does it go diff --git a/outputs/headers_footers/f9f5429bf57bd9040fb42fb73dd3cdb1941d90e5_page_5_pg1_repeat1.md b/outputs/headers_footers/f9f5429bf57bd9040fb42fb73dd3cdb1941d90e5_page_5_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3b32f5c0f5f447334d974d9e0f72da17e99cef64 --- /dev/null +++ b/outputs/headers_footers/f9f5429bf57bd9040fb42fb73dd3cdb1941d90e5_page_5_pg1_repeat1.md @@ -0,0 +1,25 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +square method. The values of \(B\) and \(C\) , so obtained, are given in Table 2 with the standard deviation, \(\sigma\) , and the probable error, \(P.E.\) , calculated by the equation + +\[P.E. = 0.6745\sigma. \quad (5)\] + +In Fig. 3, the excess viscosity of Freon-12 and Freon-22 vapours is plotted versus density. Zero-density viscosity of Freon-12 and Freon-22 vapours + +It is important to realize that the determination of viscosity at any temperature and density requires information regarding the temperature dependence of zero-density viscosity. The temperature dependence of zero-density viscosity may be represented by an equation of the form + +\[\mu_0 = B_0\sqrt{T} - C_0. \quad (6)\] + +where the constants, \(B_0\) and \(C_0\) , depend on the nature of the vapour. + +The constants, \(B_0\) and \(C_0\) , for Freon-12 and Freon-22 vapours are evaluated by matching equation (6) to the zero-density viscosity-temperature data presented in Table 1 using the method of least squares. The values of \(B_0\) and \(C_0\) , so obtained, are given in Table 3. The standard deviation is calculated by equation (4) and the probable error by equation (5). + +Table 3. Constants, \(B_0\) , \(C_0\) and reliability information for Freon-12 and Freon-22 vapours based on zero-density viscosity data given in Table 1 + +
Refrigerant Constant
\(B_0 \times 10^6\)
Constant
\(C_0 \times 10^6\)
Standard deviation
\(\sigma \times 10^6\)
Probable error
\(P.E. \times 10^6\)
Freon-12 10.57 59.77 1.6643 1.1226
Freon-22 13.25 102.65 0.5334 0.3598
+ +Fig. 3 Variation of excess viscosity of Freon-12 and Freon-22 vapours with density + +Fig. 4 Zero-density viscosity of Freon-12 and Freon-22 vapours + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/headers_footers/fc5b2acd2b4af4c9fdcf1f53d157589cba990759_page_17_pg1_repeat1.md b/outputs/headers_footers/fc5b2acd2b4af4c9fdcf1f53d157589cba990759_page_17_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7b1d02da0fc360d13543e66fd6d177664de90dc9 --- /dev/null +++ b/outputs/headers_footers/fc5b2acd2b4af4c9fdcf1f53d157589cba990759_page_17_pg1_repeat1.md @@ -0,0 +1,31 @@ +## C. Expiring Work Authorization + +Human Resources notification will initiate the reverification process by prompting the Foreign National Administrator to notify the employee of the need to reverify his or her employment eligibility in advance of the expiration and to complete reverification before the expiration of employment eligibility. Reverifying Employees in H, TN, or O Status) + +(See Section V(C)(1) Extension of Nonimmigrant Petitions: + +## D. Examining Original Documents after Receipts are Presented + +A tickler must also be kept by the Foreign National Administrator to initiate reverification for an employee who, at the time of hire presents a receipt for replacement document(s). Notification should be sent 30 days and 14 days before the expiration of the initial 90-day period of employment and should remind the employee to present the original document(s) no later than 90 days from the first day of hire. The tickler should also prompt the examination of the original document before the expiration of the 90-day period. + +# VII. Central Retention and Storage of I-9 Forms + +I-9 forms for current and terminated employees should be stored in different files. + +## A. Current Employees + +The law requires employers to properly complete and retain a Form I-9 for every current employee hired after November 6, 1986. + +All I-9 forms must be maintained separately from the employee’s personnel file. I-9s should remain stored and locked with availability to limited authorized personnel. All documents may be used only for I-9 purposes. The records may not be copied or distributed without authorization from the Vice Chancellor of Human Resources and the University’s Chief Legal Office. + +## B. Terminated Employees + +I-9 forms for terminated employees must be kept for either one year from the date of termination of employment OR three years from the date of hire, whichever is longer. + +## C. Rehires + +An employee who leaves the University, regardless of the length of separation and is subsequently rehired must complete a new Form I-9, unless the employee is being hired within 3 years of completion of the original I-9 Form and is still eligible to be employed based upon the same documentation. + +## D. Foreign National (non-immigrant) + +I-9 forms for foreign national (non-immigrant) employees will be filed separate from other I-9 forms. diff --git a/outputs/headers_footers/fc8f9a3029dced611f54efa3a2389d0cfba4680d_page_120_pg1_repeat1.md b/outputs/headers_footers/fc8f9a3029dced611f54efa3a2389d0cfba4680d_page_120_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..76c474fbc97b2327f22161c2186d1286ceb8fcc0 --- /dev/null +++ b/outputs/headers_footers/fc8f9a3029dced611f54efa3a2389d0cfba4680d_page_120_pg1_repeat1.md @@ -0,0 +1,35 @@ +majority-black district was 66.1% black, while the part placed in the majority-white district was 44.5% black. The split precinct map, APSX 269, clearly shows + +how the drafters separated majority-black blocks from majority-white blocks in + +this precinct. + +c. In the Wall Street Comm Ctr precinct, the drafters placed 817 + +blacks and 507 whites in majority-black HD 82, while they placed 51 blacks and + +229 whites in majority-white HD 81. SDX 405 at 170-71. The part of this + +precinct placed in the majority-black district was 60.3% black, while the part + +placed in the majority-white district was 17.8% black. The split precinct map, + +APSX 270, clearly shows how the drafters separated majority-black blocks from + +majority-white blocks in this precinct. + +116. Race was the predominant factor motivating the drafters’ decision to + +place a significant number of voters within or without HD 82. + +HD 83, Lee, Chambers, and Russell Counties. + +117. The drafters reached and exceeded their 57.03% black target for HD + +83 by only 0.67%. APSX 01. A net total of 4,934 persons were added to HD 83 + +to bring it within +1% deviation, 3,086 blacks and 1,595 whites. SDX 403 at 7; + +SDX 406 at 7. + +118. The drafters split the Lee County boundary in 4 House districts, the diff --git a/outputs/headers_footers/fd9f7d29b83d13c294f174e5511e5148dd729b67_page_37_pg1_repeat1.md b/outputs/headers_footers/fd9f7d29b83d13c294f174e5511e5148dd729b67_page_37_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..050e629d99ef9b26ab16aa92fcbed861b6d9dcf0 --- /dev/null +++ b/outputs/headers_footers/fd9f7d29b83d13c294f174e5511e5148dd729b67_page_37_pg1_repeat1.md @@ -0,0 +1,23 @@ +uvážiť, pretože vybraným ukazovateľom budeme merať plnenie cieľa niekoľko rokov. Inými slovami, nie je vhodné meniť ukazovatele pre ten istý cieľ každý rozpočtový rok alebo dokonca počas rozpočtového roka, pokiaľ neexistuje relevantný dôvod (napr. ak má cieľ definovaný len jeden ukazovateľ a tento každý rok meníme, stráca sa podstata sledovania plnenia cieľa v čase). Navyše vhodne zvolený ukazovateľ umožní samospráve porovnávať plnenie cieľov v rámci jednotlivých subjektov navzájom. + + + +Je merateľný - ukazovateľ by mal byť samozrejme merateľný a kvantifikovateľný, aby bolo možné jednoznačne monitorovať a hodnotiť pokrok v plnení cieľa, resp. jeho plnenie či neplnenie. + + + +Je kontrolovateľný - správnosť zistených hodnôt ukazovateľov by mala byť overiteľná a kontrolovateľná. Rovnako by mala byť overiteľná dôveryhodnosť zdroja a spôsob zberu údajov. Táto vlastnosť môže byť dôležitá z pohľadu hlavného kontrolóra mesta, ale aj z pohľadu verejnosti. + + + +Je dostupný – pri voľbe merateľného ukazovateľa musíme zvážiť dostupnosť údajov a možnosť ich zberu. Je úplne zbytočné zvoliť pre meranie cieľa ukazovateľ alebo viacero ukazovateľov, ktorých hodnoty sú nedostupné. + + + +Je nákladovo efektívny – to znamená, že náklady na zber údajov by nemali byť vyššie, ako je informačný prínos pre samosprávu a verejnosť. V opačnom prípade je nutné hľadať iné ukazovatele, ktorými je možné monitorovať a hodnotiť plnenie cieľa. + +Pozn. Tvorbe merateľných ukazovateľov sa venuje aj školiaci materiál Prezentácie popisujúce postupy + +a procesy pri tvorbe programovej štruktúry a školiaci materiál Vzorové príklady tvorby základných + +prvkov programového rozpočtovania. diff --git a/outputs/headers_footers/fe8c6edb71bea08b67e7f8cdca813a0bbba04e6e_page_3_pg1_repeat1.md b/outputs/headers_footers/fe8c6edb71bea08b67e7f8cdca813a0bbba04e6e_page_3_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..095ce2422e1a395c552205c3252b346152c1814b --- /dev/null +++ b/outputs/headers_footers/fe8c6edb71bea08b67e7f8cdca813a0bbba04e6e_page_3_pg1_repeat1.md @@ -0,0 +1,9 @@ +dieser Fortsätze ist ein gutes Unterscheidungsmerkmal für einzelne Arten dieser Gruppe. (So fehlt z. B. hei quadripunctata F. der äußere Fortsatz; der Rand der Valve ist an dieser Stelle etwas vorgezogen und abgerundet.) Charakteristisch und für die Artunterscheidung wichtig ist die Ausbildung des oberen Randes der Valve. Er weist 2 abgerundete Anhänge auf. Der untere scheint durch eine lange schleifenartige Faltung des oberen Randes gebildet zu sein. In den zweiten, ampullenartigen Anhang ragt ein Teil der schwach chitinisierten Harpe. An seiner Spitze stehen einige kurze aber kräftige Borsten. Das Tegumen ist oval, wenig länger als breit. Der bandartige Uncus verjüngt sich allmählich und endet mit scharfer Spitze. Die Bewaffnung des Penis ist verhältnismäßig schwach. In der Mitte fällt ein stärker chitinisierter Streifen, aus dicht stehenden Dornen gebildet, auf. Eine Gruppe mehr zerstreut stehender Dornen befindet sich am Ende des Rohres. In diese Gruppe gehört von den im Niederelbgebiet vorkommenden Arten neben selini B. noch quadripunctata F., von anderen europäischen Arten z. B. flavirena Guen. Eine dritte Gruppe bilden taraxaci Hb., alsines Brahm, respersa Hb. und ambigua F. Der Genitalapparat von taraxaci Hb. möge als Beispiel für diesen Typ dienen. (Abbildg. Nr. 3.) + +![](figure) + +![](figure) + +Abb. 3 Cir. fA/hefis) taraxaci Hb. (Finkenwälder). + +Die Valven sind stark einwärts gebogen. Am Ende fällt der mit dichtem Haarbesatz bedeckte Cucullus auf. Sein äußerer Rand diff --git a/outputs/headers_footers/fe8d3e95cdff195bec4dec4416d8315cce6ff669_page_16_pg1_repeat1.md b/outputs/headers_footers/fe8d3e95cdff195bec4dec4416d8315cce6ff669_page_16_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..cdd93d8d76908b36beafdda05ff830ef1da865ea --- /dev/null +++ b/outputs/headers_footers/fe8d3e95cdff195bec4dec4416d8315cce6ff669_page_16_pg1_repeat1.md @@ -0,0 +1,11 @@ +of the equality of force electrical and magnetic components Fe = Fg and the equality of the distances roe and rog between the electrical and magnetic charges, respectively: + +\[r_{eo}=r_{go}=0.5L_{qo}=0,37\cdot10^{-25}m\] (2.9) + +\[_{_{_{_{_{_{_{}}}}}}}F_{F_{F_{g}^{e_{e}}}}=_{=_{=}F4_{4\mu}\pi_{\pi^{g_{0}}}\varepsilon_{r^{0}g_{g^{2}0}^{2}}r_{=^{e0}}^{2}}^{1e^{2}}=_{1.}1_{6}.6_{\cdot1}\cdot_{0}1_{2}0_{N^{33}}^{2}N\] (2.10) + +The solution of the system (2.10) is obtained under the condition \(\varepsilon_{0}\mu_{0}С_{0}^{2}=1\) + +\[g= \frac{1}{\varepsilon_{0}\mu_{0}} e=C_{0}e\] (2.11) + +It may be seen that only when the parameters of the electrical and magnetic components inside the quanton are equal, in particular for the Coulomb forces (2.10), the relationship (2.11) between the values of the elementary magnetic and electrical charges corresponds to the previously determined relationship (2.6). Shorter distances between the charges inside the quanton determine colossal attraction forces (2.10) which characterise the quantised space-time by colossal elasticity. Thus, the electromagnetic symmetry of the quanton determines the relationships (2.6) and (2.1) and also the correspondence of these relationships to the Maxwell equations (2.3) and the Coulomb law (2.10). The Dirac relationship (2.2) does not correspond to (2.3) and (2.10), is not written in the SI system and uses the procedure based on the unambiguous yield of the phase of the wave function of the electron whose parameters include not only the elementary electrical charge e but also other parameters, which determine the wave properties of the electron in the quantised spacetime. It should be accepted that as regards the procedure, Dirac made an error but this does not reduce role in the investigations of the magnetic monopole. In the pure form, the monopole elementary electrical and magnetic charges are included only in the structure of the quanton, and the analysis of the properties of the quanton yielded the true relationships (2.6) and (2.11). In fact, the forces (2.10) inside the quanton are colossal in magnitude diff --git a/outputs/long_tiny_text/10a_pg1_pg1_repeat1.md b/outputs/long_tiny_text/10a_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..99b291c7f31e9798a55de970e7099f75bf332390 --- /dev/null +++ b/outputs/long_tiny_text/10a_pg1_pg1_repeat1.md @@ -0,0 +1,84 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +correctly: 'What do you think Jenny will do next?' 'It's hard to tell.' I could tell that he had enjoyed the evening. You can never tell what he's going to say next. I can't tell the difference between Dan's sisters. 4 [T] (used about a thing) to give information to sb: This book will tell you all you need to know. 5 [I] to not keep a secret: Promise you won't tell! 6 [I] ~ (on sb/sth) to have a noticeable effect: I can't run as fast as I could – my age is beginning to tell! + +[DM] all told with everyone or everything counted and included + +(I'll) tell you what (informal) used to introduce a suggestion: I'll tell you what – let's ask Diane to take us. I told you (so) (informal) I warned you that this would happen + +tell A and B apart → APART + +tell the time to read the time from a clock or watch +PHRV tell sb off (for sth/for doing sth) to speak to sb angrily because they have done sth wrong: The teacher told me off for not doing my homework. +tell on sb to tell a parent, teacher, etc. about sth bad that sb has done + +teiling /'telɪŋ/ adj. 1 showing, without intending to, what sb/sth is really like: The number of homeless people is a telling comment on today's society. +2 having a great effect: That's quite a telling argument. + +telltale /'telteɪl/ adj. giving information about sth secret or private: He said he was fine, but there were telltale signs of worry on his face. + +tellurium /te'luəriəm/ noun [U] (symbol Te) (CHEMISTRY) a chemical element. Tellurium is a shiny silver-white substance that breaks easily, found in SULPHIDE ORES. For more information on the periodic table of elements, look at pages R34-5. + +telly /'teli/ (pl. tellies) (BrE, informal) = TELEVISION + +telnet /"telnet/ noun [U] (COMPUTING) a computer system which allows you to use data and programs on another computer; a connection made using this system ▶ telnet verb (telnetting; telnetted) [T] + +temp\(^{1}\) /temp/ noun [C] (informal) a temporary employee, especially in an office, who works somewhere for a short period of time when sb else is ill or on holiday ▶ temp verb [I] + +temp\(^{2}\) abbr. temperature: temp 15°C + +temper /'tempə(r)/ noun 1 [C,U] if you have a temper you get angry very easily: Be careful of Paul. He's got quite a temper! ☐ You must learn to control your temper. 2 [C] the way you are feeling at a particular time: It's no use talking to him when he's in a bad temper. SYN mood + +IDM in a temper feeling very angry and not controlling your behaviour + +keep/lose your temper to stay calm/to become angry look at bad-tempered + +temperament /'temprə'ment/ noun [C,U] a person's character, especially as it affects the way they behave and feel: to have an artistic/a fiery/a calm temperament + +temperamental /,temprə'mentl/ adj. often and suddenly changing the way you behave or feel + +temperate /'temparat/ adj. (used about a climate) not very hot and not very cold + +temperature =0 /'tempratfa(r)/ noun + +1 [C,U] how hot or cold sth is: Heat the oven to a temperature of \(200^{\circ}\)C. ☐ a high/low temperature ☐ an increase in temperature 2 [C] how hot or cold a person's body is + +have a temperature (HEALTH) (used about a person) to be hotter than normal because you are ill take sb's temperature (HEALTH) to measure the + +temperature of sb's body with a special instrument (a thermometer) + +template /'templt/ noun [C] 1 a shape cut out of a hard material, used as a model for producing exactly the same shape many times in another material 2 a thing that is used as a model for producing other similar examples: If you need to write a lot of similar letters, set up a template on your computer. + +temple /'templ/ noun [C] 1 (RELIGION) a building where people pray to a god or gods: a Buddhist/Hindu temple 2 (ANATOMY) one of the flat parts on each side of your FOREHEAD → picture on page 80 + +tempo /'tempəʊ/ noun (pl. tempos /'tempəuz/) 1 [sing., U] the speed of an activity or event 2 [C,U] (MUSIC) the speed of a piece of music: a fast/slow tempo + +temporary → AW /'temprəri/ adj. lasting for a short time; not permanent: a temporary job +This arrangement is only temporary. +temporarily /'temprəri/ adv. + +tempt /tempt/ verb [T] ~ sb (into sth/into doing sth); ~ sb (to do sth) to try to persuade or attract sb to do sth, even if it is wrong: His dream of riches had tempted him into a life of crime. She was tempted to stay in bed all morning. + +temptation /temp'teɪʃn/ noun 1 [U] a feeling that you want to do sth, even if you know that it is wrong: I managed to resist the temptation to tell him what I really thought. She wanted a cigarette badly, but didn't give in to temptation. 2 [C] a thing that attracts you to do sth wrong or silly: All that money is certainly a big temptation. + +tempting /'temptɪŋ/ adj. attractive in a way that makes you want to do or have sth: a tempting offer + +ten /ten/ number 10 + +tenacious /tə'neɪʃəs/ adj. not likely to give up or let sth go; determined ▶ tenacity /tə'naesəti/ noun [U] + +tenancy /'tenənsi/ noun [C,U] (pl. tenancies) the use of a room, flat, building or piece of land, for which you pay rent to the owner: a six-month tenancy ☐ It says in the tenancy agreement that you can't keep pets. + +tenant /'tenant/ noun [C] a person who pays money (rent) to the owner of a room, flat, building or piece of land so that they can live in it or use it: They had evicted their tenants for non-payment of rent. +tenant farmers (=ones who do not own their own farms) look at landlady, landlord + +tend =0 /tend/ verb 1 [I] ~ to do sth to usually do or be sth: Women tend to live longer than men. +There tends to be a lot of heavy traffic on that road. +My brother tends to talk a lot when he's nervous. +2 [I] used for giving your opinion in a polite way: I tend to think that we shouldn't interfere. 3 [I,T] (formal) ~ (to) sb/sth to look after sb/sth: Paramedics tended (to) the injured. + +tendency =0 /'tendensi/ noun [C] (pl. tendencies) a ~ (to do sth/towards sth) something that a person or thing usually does; a way of behaving: They both have a tendency to be late for appointments. The dog began to show vicious tendencies. She seems to have a tendency towards depression. + +tender\(^{1}\) /'tenda(r)/ adj. 1 kind and loving: tender words/looks/kisses 2 (used about food) soft and easy to cut or bite; not tough: The meat should be nice and + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/10b_pg1_pg1_repeat1.md b/outputs/long_tiny_text/10b_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c2cde46402e22006c22f031ec0c3004923a64194 --- /dev/null +++ b/outputs/long_tiny_text/10b_pg1_pg1_repeat1.md @@ -0,0 +1,89 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +snowboard /'snəʊbɔːd/ noun [C] a type of board that you fasten to both your feet and use for moving down mountains that are covered with snow +▶ snowboarder noun [C] ▶ snowboarding noun [U]: Have you ever been snowboarding? + +snowdrift /'snəʊdrift/ noun [C] a deep pile of snow that has been made by the wind: The car got stuck in a snowdrift. + +snowdrop /'snəʊdrɒp/ noun [C] a type of small white flower that appears at the end of winter + +snowed 'in adj. not able to leave home or travel because the snow is too deep + +snowed 'under adj. with more work, etc. than you can deal with + +snowfall /'snəʊfɔːl/ noun 1 [C] the snow that falls on one occasion: heavy snowfalls 2 [U] the amount of snow that falls in a particular place + +snowflake /'snəʊfleɪk/ noun [C] one of the small, soft, white pieces of frozen water that fall together as snow + +snowman /'snæumæn/ noun [C] (pl. -men /-men/) the figure of a person made out of snow + +snowplough (AmE snowplow) /'snəʊplɔː/ noun [C] a vehicle that is used to clear snow away from roads or railways → look at plough + +snowy /'snəʊi/ adj. with a lot of snow: snowy weather ◇ a snowy scene + +Snr (also Sr) abbr. (especially AmE) Senior + +snub /snʌb/ verb [T] (snubbing; snubbed) to treat sb rudely, for example by refusing to look at or speak to them ▶ snub noun [C] + +snuck /snvk/ (informal) (especially AmE) past tense, past participle of sneak\(^{1}\) + +snuff /snʌf/ noun [U] (especially in past times) +TOBACCO which people breathe up into the nose in the form of a powder + +snuffle /'snʌfl/ verb [I] (used about people and animals) to make a noise through your nose + +snug /snʌg/ adj. 1 warm and comfortable: a snug little room ◇ The children were snug in bed. 2 fitting sb/sth closely: Adjust the safety belt to give a snug fit. ▶ snugly adv. + +snuggle /'snʌgl/ verb [I] ~ (up to sb); ~ (up/down) to get into a position that makes you feel safe, warm and comfortable, usually next to another person: She snuggled up to her mother. ◇ I snuggled down under the blanket to get warm. + +SO\(^{1}\) w0 /səʊ/ adv. 1 used to emphasize an adjective or adverb, especially when this produces a particular result: She's so ill (that) she can't get out of bed. ◇ He was driving so fast that he couldn't stop. ◇ You've been so kind. How can I thank you? 2 used in negative sentences for comparing people or things: She's not so clever as we thought. 3 used in place of something that has been said already, to avoid repeating it: Are you coming by plane? If so, (= if you are coming by plane) I can meet you at the airport. ◇ 'I failed, didn't I?' 'I'm afraid so.' 4 (not with verbs in the negative) also, too: He's a teacher and so is his wife. ◇ 'I've been to New York.' 'So have I.' ◇ I like singing and so does Helen. 5 look at neither 5 used to show that you agree that sth is true, especially when you are surprised: 'It's getting late.' 'So it is. We'd better go.' 6 (formal) (used when you are showing sb sth) in this way; like this: It was a black insect, about so big (=using your hands to show the size). ◇ Fold the paper in two diagonally, like so. + +and so on (and so forth) used at the end of a list to show that it continues in the same way: They sell pens, pencils, paper and so on. + +I told you so used to tell sb that they should have + +listened to your advice: 'I missed the bus.' 'I told you so. I said you needed to leave earlier.' + +it (just) so happens (used to introduce a surprising fact) by chance: It just so happened that we were going the same way, so he gave me a lift. + +just so → JUST\(^{1}\) + +or so (used to show that a number, time, etc. is not exact) approximately; about: A hundred or so people came to the meeting. + +so as to do sth with the intention of doing sth; in order to do sth + +so much for used for saying that sth was not helpful or successful: So much for that diet! I didn't lose any weight at all. + +that is so (formal) that is true + +SO\(^{2}\) w0 /səʊ/ conj. 1 with the result that; therefore: She felt very tired so she went to bed early. 2 ~ (that) with the purpose that; in order that: She wore dark glasses so (that) nobody would recognize her. 3 used to show how one part of a story follows another: So what happened next? + +IDM so what? (informal) (showing that you think sth is not important) Who cares?: 'It's late.' 'So what? We don't have to go to school tomorrow.' + +soak /səʊk/ verb 1 [I,T] to become or make sth completely wet: Leave the dishes to soak for a while. ◇ The dog came out of the river and shook itself, soaking everyone. 2 [I] ~ into/through sth; ~ in (used about a liquid) to pass into or through sth: Blood had soaked through the bandage. + +PHRV soak sth up to take sth in (especially a liquid): I soaked the water up with a cloth. + +soaked /səʊkt/ adj. (not before a noun) extremely wet: I got soaked waiting for my bus in the rain. + +soaking /'səʊkɪŋ/ (also, soaking 'wet) adj. extremely wet + +'so-and-so noun [C] (pl. so-and-sos) (informal) 1 a person who is not named: Imagine a Mrs So-and-so telephones. What would you say? 2 a person that you do not like: He's a bad-tempered old so-and-so. + +soap w0 /səup/ noun 1 [U] a substance that you use for washing and cleaning: He washed his hands with soap. ◇ a bar of soap ◇ soap powder (=for washing clothes) 2 [C] (informal) =SOAP OPERA ▶ soapy adj. + +'soap opera (also informal soap) noun [C] (ARTS AND MEDIA) a story about the lives and problems of a group of people which continues several times a week on television or radio + +soar /sɔː(r)/ verb [I] 1 to fly high in the air 2 to rise very fast: Prices are soaring because of inflation. + +soaraway /'sɔːrəweɪ/ adj. (BrE) (used especially about success) very great; growing very quickly + +sob /spb/ verb [I] (sobbing; sobbed) to cry while taking in sudden, sharp breaths; to speak while you are crying: The child was sobbing because he'd lost his toy. ▶ sob noun [C]: It was heartbreaking to listen to her sobs. + +sober\(^{1}\) /'səʊba(r)/ adj. 1 (of a person) not affected by alcohol: He'd been drunk the first time he'd met her, but this time he was stone-cold sober. 2 not funny; serious: a sober expression ◇ Her death is a sober reminder of just how dangerous drugs can be. 3 (of a colour) not bright or likely to be noticed: a sober grey suit + +sober\(^{2}\) /'saʊba(r)/ verb + +PHRV sober (sb) up to become or make sb become normal again after being affected by alcohol: I need + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/10c_pg1_pg1_repeat1.md b/outputs/long_tiny_text/10c_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..135dacaa5f492e28a52a731f2782005e521d90d6 --- /dev/null +++ b/outputs/long_tiny_text/10c_pg1_pg1_repeat1.md @@ -0,0 +1,80 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +parliament \(w^{0}\) /'pɑːləmənt/ noun (POLITICS) + +1 [C] the group of people who are elected to make and change the laws of a country 2 Parliament [sing.] the parliament of the United Kingdom: a Member of Parliament (MP) + +CULTURE + +Parliament + +The UK Parliament consists of the House of Lords, whose members have been appointed rather than elected, and the House of Commons, whose members have been elected by the people to represent areas of the country (called constituencies). + +parliamentary /,pɑːləˈmentri/ adj. (only before a noun) (POLITICS) connected with parliament + +parody /'pæradi/ noun [C,U] (pl. parodies) (LITERATURE) a piece of writing, speech or music that copies the style of sb/sth in a funny way: a parody of a spy novel ▶ parody verb [T] (pres. part. parodying; 3rd person sing. pres. parodies; pt, pp parodied) + +parole /pəˈrəʊl/ noun [U] (LAW) permission that is given to a prisoner to leave prison early on the condition that they behave well: He's going to be released on parole. + +parrot /'pærət/ noun [C] a type of tropical bird with a curved beak and usually with very bright feathers. Parrots that are kept as pets can be trained to copy what people say. + +'parrot-fashion adv. without understanding the meaning of sth: to learn sth parrot-fashion + +parsley /'pɑːsli/ noun [U] a plant with small leaves that are used in cooking and for food decoration as a HERB + +parsnip /'pɑːsnɪp/ noun [C] a long thin white vegetable, that grows under the ground + +part\(^{1}\) w0 /pɑːt/ noun 1 [C,U] (a) ~ (of sth) one of the pieces, areas, periods, things, etc. that together with others forms the whole of sth; some, but not all of sth: Which part of Spain do you come from? The film is good in parts. spare parts for a car a part of the body Part of the problem is lack of information. I enjoy being part of a team. 2 [C] (ARTS AND MEDIA) a role or character in a play, film, etc.: He played the part of Macbeth. I had a small part in the school play. 3 parts [pl.] a region or an area: Are you from these parts? 4 (ARTS AND MEDIA) [C] a section of a book, television series, etc.: You can see part two of this programme at the same time next week. 5 [C] an amount or quantity (of a liquid or substance): Use one part cleaning fluid to ten parts water. + +the best/better part of sth most of sth; more than half of sth, especially a period of time: They've lived here for the best part of forty years. + +for the most part usually or mostly + +for my/his/their, etc. part speaking for myself, himself, etc.; personally + +have/play a part (in sth) to be involved in sth in part not completely: The accident was, in part, the fault of the driver. + +on the part of sb/on sb's part made, done or felt by sb: There is concern on the part of the teachers that class sizes will increase. I'm sorry. It was a mistake on my part. + +take part (in sth) to join with other people in an activity: Everybody took part in the discussion. + +part\(^{2}\) /pɑːt/ verb 1 [I,T] (formal) ~ (sb) (from sb) to leave or go away from sb; to separate people or things: We exchanged telephone numbers when we parted. He hates being parted from his children for long. 2 [I,T] to move apart; to make things or people + +move apart: Her lips were slightly parted. 3 [T] to separate the hair on the head with a COMB in order to make a clear line: She parts her hair in the middle. look at parting + +IDM part company (with sb/sth) to go different ways or to separate after being together + +PHRV part with sth to give or sell sth to sb: When we went to live in Italy, we had to part with our horses. + +part\(^{3}\) /pɑːt/ adv. not completely one thing and not completely another: She's part Russian and part Chinese. + +part ex'change noun [U] a way of buying sth, such as a car, in which you give your old one as some of the payment for a more expensive one + +partial /'pɑːʃl/ adj. 1 not complete: The project was only a partial success. 2 (old-fashioned) ~ to sth liking sth very much: He's very partial to ice cream. +▶ partially adv. + +partiality /,pɑːfiˈæləti/ noun [U] (formal) unfair support for one person, team, etc. above another: The referee was accused of partiality towards the home team. OPP impartiality + +participant AW /pɑːˈtɪsɪpənt/ noun [C] a person who takes part in sth + +participate AW /pɑːˈtɪsɪpərt/ verb [I] ~ (in sth) to take part or become involved in sth: Students are encouraged to participate in sporting activities. +▶ participation AW /pɑː, tɪsɪˈpeɪʃn/ noun [U] +▶ participatory AW /pɑː, tɪsɪˈpeɪtəri/ adj.: Ordinary people had no participatory role in the Government. + +participle /'pɑːtɪsɪpl; ,pɑːtɪsɪpl/ noun [C] (LANGUAGE) a word that is formed from a verb and that ends in -ing (present participle) or -ed, -en, etc. (past participle). Participles are used to form TENSES of the verb, or as adjectives: 'Hurrying' and 'hurried' are the present and past participles of 'hurry'. + +particle /'pɑːtɪkl/ noun [C] 1 a very small piece; a bit: dust particles 2 (PHYSICS) a very small piece of matter, such as an ELECTRON or PROTON, that is part of an atom look at alpha particle, elementary particle 3 (LANGUAGE) a small word that is not as important as a noun, verb or adjective: In the phrasal verb 'break down', 'down' is an adverbial particle. + +particular w0 /pəˈtɪkjælə(r)/ adj. 1 (only before a noun) used to emphasize that you are talking about one person, thing, time, etc. and not about others: Is there any particular dish you enjoy making? 2 (only before a noun) greater than usual; special: This article is of particular interest to me. 3 connected with one person or thing and not with others: Everybody has their own particular problems. 4 ~ (about/over sth) (not before a noun) difficult to please: Some people are extremely particular about what they eat. look at fussy + +IDM in particular especially: Is there anything in particular you'd like to do this weekend? + +particularly w0 /pəˈtɪkjæləli/ adv. + +especially; more than usual or more than others: I'm particularly interested in Indian history. The match was excellent, particularly the second half. + +particulars /pəˈtɪkjæləz/ noun [pl.] (formal) facts or details about sb/sth: The police took down all the particulars about the missing child. + +parting /'pɑːtɪŋ/ noun 1 [C,U] saying goodbye to, or being separated from, another person (usually for quite a long time) 2 [C] the line in a person's hair + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg145_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg145_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1ec37067c2a0f2609dee69b9fd3eca13a62b187e --- /dev/null +++ b/outputs/long_tiny_text/11_pg145_pg1_pg1_repeat1.md @@ -0,0 +1,161 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Gl. ii. 38; Wilbraham, p. 107; Forby, ii. 249. To perk one's self up, to adorn. To perk up again, to recover from sickness. + +(4) A perch. Suffolk. "Ovyr the perke to pryk," Skelton, i. 124. It also occurs in Reliq. Antiq. i. 294. + +(5) A wooden frame against which sawn timber is set up to dry. East . + +PERKERS. Youngrooks. North . + +PERKIN. Water cyder. + +PERKY. Saucy; obstinate. West . + +PERLATANE. + +The haule also of this palace was sett fulle of ymagez of golde, and bitwix thame stode perlatanes of golde, in the branches of whilke ther were many maners of fewles. MS. Lincoln A. i. 17, f. 25. + +PERLESY. A pleurisy. + +And smytts hym als it were with a perlesy, that alle his lymes dryes, that he may na gud do als he sulde. MS. Lincoln A. i. 17, f. 246. + +PERLID. Ornamented with pearls; studded with any ornaments. + +And many a perlid garncment + +Embroudid was agen the day. + +Gower, MS. Soc. Antiq. 134, f. 54. + +PERLIN. The piece of timber which runs along under the middle part of the spars or bearers of a roof, to give such bearers additional strength. + +PERLOWES. Perilous. Palsgrave . + +PERMAFAY. By my faith. (A.-N.) + +PERMANSIE. Magic; necromancy. + +PERN. (1) To prosper. Somerset . + +(2) To pick and dress birds, particularly applied to dressing the heron. + +PERNASO. Mount Parnassus. + +PERNEL. The pimpernel, a flower that always shuts up its blossoms before rain. + +But these tender pernels must have one gown for the day, another for the night. + +- Pilkington's Works , p. 56. + +PERPEND. To consider attentively. + +You'll quickly know, if you do well perpend , + +And observe rightly what's the proper end. + +Brome's Songs , 1661, p. 182. + +PERPENDICLE. The plumb line of a quadrant. This word occurs in an old treatise on mensuration, in MS. Sloane 213. + +PERPENTINE. A porcupine. "Perpoynt, hystrix," Pr. Parv. The form perpentine occurs in Shakespeare, most incorrectly altered to porcupine by modern editors. It is the genuine old word. + +PERPENT-STONE. A large stone reaching through a wall so as to appear on both sides of it. Oxf. Gl. Arch. p. 280. In the North of England, a thin wall, the stones of which are built on the edge, is called a perpent . + +PERPETUANA. A kind of glossy cloth, generally called everlasting . + +PERPLANTED. Planted securely. + +Requirnyge them as his especiall truste and confidence was planted in the hope of their fidelité, that they would occurre and mete hym by the waye with all diligent preparation. + +Hall, Richard III. f. 27. + +PERQUIRE. To search into. Clobery's Divine Glimpses, 1659, p. 73. + +PERR. (1) Perry. (2) A pearl. + +PERRE. A dish in old cookery, made chiefly of peas, onions, and spices. + +PERRIER. A kind of short mortar, formerly much used for stone shot. + +PERRIWINKLE. A periwig. Stubbe . + +PERRONENDERE. A pardoner. Hearne . + +PERRY-DANCERS. The aurora borealis. East . + +PERRYE. (1) A squall. + +It happened Harold his sonne to arrive at Pountiou against his will, by occasion of a sudden perry , or contrarie winde, that arose while he was on seaboorde. Lambarde's Perambulation , 1596, p. 357. + +(2) A little cur dog. North . + +(3) Precious stones; jewels. (A.-N.) + +And alle was set with perrye , + +Ther was never no better in Crystyanté. + +MS. Cantab. Ff. ii. 38, f. 242 + +PERS. (1) Persia. + +We woot bothe bi story and vers + +That the kyndam of Grace and Pers + +Were hede kyngus in forme tilde. + +Cursor Mundi , MS. Coll. Trin. Cantab. f. 132. + +(2) Company. + +Al we wite it thi default, + +So siggeth al our perss . + +Arthur and Merlin , p. 9. + +(3) Sky, or blueish gray colour. There was a kind of cloth so called. + +PERSAUNT. Piercing. (A.-N.) + +That of the stremis every maner wyzte + +Astonied was, they were so bryzte and shene, + +Ant to the ye for persaunt for to sene. + +Lydgate, MS. Soc. Antiq. 134, f. 23. + +For thy persecynt charité. + +Gower, MS. Soc. Antiq. 134, f. 109. + +PERSCRUTE. To search through. (Lat.) Used by Andrew Borde, Brit. Bibl. iv. 24. + +PERSE. Equality. (A.-N.) + +PERSEL. Parsley. Pegge . + +PERSEVER. To persevere. Shak. + +Whether a daw sit, or whether a daw fly, Whether a daw stand, or whether a daw lye, Whether a daw creep, or whether a daw cry, In what case soever a daw persever , A daw is a daw, and a daw shall be ever. + +Tarlton's Jests , 1611. + +PERSIAN-WHEEL. An engine invented to raise a quantity of water sufficient for over-flowing lands, that border in the banks of rivers, where the streams lie so low, as to be incapable of doing it. + +PERSON. A mask, or actor. (Lat.) + +PERSONABLE. Personally visible. + +My saied lorde of Winchester saied unto the kyng that the kyng his father, so visited with sickness, was not personable . Hall, Henry VI. f. 13. + +PERSONE. A man. Generally, a man of dignity, a parson or rector of a church. + +PERSORE. A piercing-iron. + +3e, 3e, seyd the persore , That at I sey it shall be sure; Whi chyd 3e lche one with other? Wote 3e wele I ame your brother! Therefore none contrary me, Fore as I sey so schall it be. MS. Ashmole 61. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg146_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg146_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0689c2470fe0b426c77f7907068de7cbe08c7ffb --- /dev/null +++ b/outputs/long_tiny_text/11_pg146_pg1_pg1_repeat1.md @@ -0,0 +1,89 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +PERSPECTIVE. A reflecting-glass. PERSPICIL. An optic-glass. It occurs in Albumazar, 1634, sig. B. iv. PERSTAND. To understand. Peele. PERSUADE. Persuasion. PERSUADERS. Spurs. Also, pistols. PERSWAY. To mitigate. Ben Jonson, iv. 428. PERT. Beautifully delicate. It is the translation of subtilis in Gesta Rom. p. 142. + +For hete her clothes down sche dede Almost to her gerdyl stede, Than lay sche uncovert; Sche was as whyt as lylye yn May, Or snow that sneweth yn wynterys day, He seygh never non so pert. + +Illustrations of Fairy Mythology, p. 11. + +PERTE. (1) To part. Still in use. Then Thomas a sory man was he, The terys ran out of his een gray; Lufly lady, yet tell thou me If we shalle perte for ever and ay. MS. Cantab. Ff. v. 48, f. 125. + +(2) Of good appearance. Ther was no man in the kynges lande More perte then was he. MS. Cantab. Ff. ii. 33, f. 244. + +PERTELICHE. Openly. (A.-N.) Than syr Priamous the prynce in presens of lordes Presez to his penowne, and pertly it hentes. Morte Arthure, MS. Lincoln, f. 84. + +PERTELOTE. The name of a hen. PERTENERE. A partner. God graunt us mekenesse in angurs here, And grace to lede owre lyfe here soo, That may aftur be pertenere Of hevene, when we hens schall goo. + +MS. Cantab. Ff. ii. 38, f. 14. + +PERTRYCHE. A partridge. Right as the pertryche is constreyned undir the claues and nayles of the hauke, is as halfe deed for drede. Caxton's Divers Fruytful Ghostly Maters. + +PERTURBE. To trouble. Palsgrave. + +PERTY. Part. Lydgate. God that sittis in Trinité, Gyffe thaym grace wel to the, That lystyns me a whyle; Alle that lovys of melody, Off hevon blisse God graunte them perty, Theyrr soules shelde fro peryle. MS. Cantab. Ff. v. 48, f. 47. + +PERUR. A kind of cup. PERUSE. To examine, or survey. + +Monsieur Soublez having perused the fleet, returned to the king, and told him there was nothing ready; and that the mariners and souldiers would not yeeld to goe the voyage till they were paid their arrears. MS. Harl. 383. + +PERVEY. To provide. (A.-N.) PERVINKE. The herb periwinkle. (A.-S.) PERYE. A pear-tree. (A.-N.) + +But for hur lorde sche durste not done, That sate benethe and pleyed hym merye, Before the towre undur a perye. + +MS. Cantab. Ff. ii. 38, f. 141. + +PERYSSE. Pears. (A.-N.) Then was the tre ful of ripe perysse, And began down to falle. + +MS. Cantab. Ff. v. 48, f. 114. + +PESANE. A gorget of mail or plate attached + +to the helmet. "A pesane and a paunsone," MS. Morte Arthure, f. 89. + +PESATE. Is when a managed horse rises hand-somely before and upon his haunches, and at the same time bends his fore-legs up to his body. PESE. (1) Peace. Perceval 980, 981. + +(2) To sooth; to appease. Tylle y be sewre of youre hartys ese, Nothing but hit may my grevys pese. + +MS. Cantab. Ff. i. 6, f. 132. + +PESEN. Peas. This is the common early form of the word, and occurs in Chaucer, Legende of Good Women, 648. Holloway gives the following couplet, as seen lately on a board in a pea-field in Berkshire—Shut the gate after you, I'll tell you the reason, Because the pigs shouldn't get into the peason. Ben Jonson has made the same words rhyme in his 133d epigram. As for his sallets, better never was Then acute sorrell, and sweet three-leav'd grasse, And for a sawce he seldome is at charges, For every crab-tree doth affoord him vergls; His banket sometimes is greene beans and peason, Nuts, peares, plumbes, apples, as they are in season. + +Taylor's Workes, 1630, i. 97. + +PESIBLE. Peaceable. (A.-N.) PESIBLETE. A calm. (A.-N.) PESK. A peach. Nominale MS. + +PESON. An instrument in the form of a staff, with balls or crockets, used for weighing before scales were employed. + +PESS. A hassock. Suffolk. + +PESSCOD-SCALDING. A kind of merry-making in summer evenings; the treat, green field peas boiled in the shells. Yorksh. + +PESSIPE. A kind of cup. + +PESTERED. Crowded. Peele, ii. 235. + +PESTERMENT. Embarrassment. North. + +PESTLE. (1) A leg of an animal, generally of a pig. A pestle of pork is still in common use. "Pestels of venison," Warner's Antiq. Culin. p. 98. "Pestell of flesshe, jambon," Palsgrave. A pestle-pie is a large standing pie which contains a whole gammon, and sometimes a couple of fowls and a neat's tongue, a favorite dish at country fairs, and at Christmas feasts. + +(2) A constable's staff. + +PESTLE-HEAD. A blockhead. + +PETE. Pity. See Cov. Myst. + +Long lay the kyng, there away wolde not hee; Dayly he propherld batayle: the enmys durst not fyghte Lacke of logynge and vitayle It was grett peté, Causid the gentill prynce to remeve, siche was Goddes myyte! + +Lowe, how the good Lorde his owne gentill knygte, Because he shulde remember hym In wele and in woo, Thus in every thyng, Lorde, thy wille be doo! + +MS. Bibl. Reg. 17 D. xv. + +PETEOSE. Merciful; compassionate. + +Many men spekes of lamentacioun, Off moders and of their gret desolatioun, Which that they did indure When that their childer dy and passe, But of his peteose tender moder, alasse! I am verray sure, + +The wo and payn passis alle othere. + +MS. Bodl. e Mus. 160. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg161_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg161_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8527da9f4d7af243026da5df13c83e314d7dbc34 --- /dev/null +++ b/outputs/long_tiny_text/11_pg161_pg1_pg1_repeat1.md @@ -0,0 +1,157 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +PLOWEFERE. Companion in play. (A.-S.) PLOWKKY. Covered with pimples. + +For hyme that is smetyne with his awenne blode, and spredls over alle his lymmes, and waxes plowkky, and brekes owte. MS. Lincoln Med. f. 294. + +PLOW-LODE. "Caracuta, plow lode," Nominale MS. It seems to be the same as Plough-land, q. v. + +PLOWMELL. A small wooden hammer occasionally fixed to the plough, still used in the North; in the Midland counties in its stead is used a plough-hatchet. + +PLOWRING. Weeping. Prompt. Parv. + +PLOWSHO. A ploughshare. Kennett. + +POY. A merry-meeting. North. + +POYE. A plough. Nominale MS. + +PLUCK. (1) Courage. Var. dial. "To pluck up one's heart," to be bold, to rejoice. Against the pluck, i. e. against the inclination. + +(2) To pluck a crow or goose with any one, i. e. to quarrel with him. + +(3) To pluck a rose, i. e. to go to the jakes, said of women. Middleton, iv. 222. + +(4) A dry pluck, i. e. a severe stroke. + +This same is kind cuckolds luck: These fellowes have given me a drie pluck, Now I have never a crose to blesse me. + +Mariage of Witt and Wisdome, 1579. + +(5) + +Our kynge and Robyn rode togyder, Forsoth as I you say, And they shote plucke buffet, As they went by the way. Robin Hood, i. 75. + +(6) Same as (1)? + +— I had the luck To see, and drink a little pluck. Brome's Songs, 1661, p. 167. + +(7) A student who fails in an university examination is said to be plucked. + +PLUCKING. The worsted plucked from the machine while the wheel is turning. North. + +PLUERE. Weeping. (A.-N.) + +PLUF. A tube of tin through which boys blow peas. Linc. Also called a pluffer . + +PLUFE. A plough. Yorksh. + +PLUFFY. Spongy; porous. Devon. It is sometimes explained, soft, plump. + +PLUG. A dwarfish fellow. East. + +PLUM. (1) Light; soft. West. + +(2) Sensible; honest. North. + +(3) Very; exceedingly. Kent. + +(4) Straight; upright; perpendicular. Plum downe, Cotgrave in v. Escarpé. + +(5) Plum round, quite round. "Make their attire to sit plum round," Harrison, p. 172. Plum fat, Florio, p. 33. + +PLUMAKIN. The magnum-bonum plum. + +PLUME. To pick or pluck the feathers off a hawk or other bird. + +PLUMED-SWAN. A white colour. One of the terms of ancient alchemy. + +PLUMMY. Soft; wet; mouldy. Devon. + +PLUMP. (1) Dry; hard. Kent. + +(2) A clump of trees. North. + +(3) A crowd of people; a mass of anything. It is sometimes a verb, to collect together. + +"Assemble theymselfes in plumpes," More's Supplycacyon of Soulys, sig. F. ii. Rydes into rowte his dede to revenge, Presede into the plumpe and with a prynce metes. + +Morte Arthure, MS. Lincoln, f. 76. + +When kynge Richard perceived that the people by plumpes fled from hym to Duke Henry. + +Hall's Union, 1548. + +(4) A pump; a draw-well. Cornw. + +(5) A hard blow. Var. dial. + +(6) Directly; exactly. Var. dial. Forby has plumpendicular, perpendicular. + +PLUM-PORRIDGE. Porridge with plums in it, a favourite dish at Christmas in some parts of the country. It is mentioned as part of Christmas fare in the Humourist, ed. 1724, p. 22, and by Addison. + +PLUMP-PATE. A thick-headed fellow. + +PLUMPY. To churn. Cornw. + +PLUMTEN. Plunged. Weber. + +PLUM-TREE. The female pudendum. Have at the plum tree seems to have been either the burden of a song or a proverbial phrase. It occurs in Middleton, although Mr. Dyce does not seem to be acquainted with the meaning of the term itself, which may be gathered from Cotgrave, in v. Hoche-prunier , and the Marriage of Witt and Wisdome, p. 16. + +PLUNGE. (1) A deep pool. Somerset. + +(2) A strait or difficulty. Greene. + +PLUNGY. Wct; rainy. (A.-N.) + +PLUNKET. A coarse woollen cloth. + +PLUNKY. Short; thick; heavy. East. + +PLUNT. A walking-stick, generally one which has a large knob. Glouc. + +PLURISY. Superabundance. Shak. + +PLUSHES. The thin hoops which hold a besom together. West. + +PLY. To bend; to consent, or comply. Still in use in Dorset, Barnes's Gl. + +PLYER. A very common bawd. + +PLYMOUTH-CLOAK. A cane, or stick. So called, says Ray, "because we use a staff in cuerpo , but not when we wear a cloak." + +PO. A peacock. (A.-S.) + +A pruest proud ase a po, Seththe weddeth us bo. + +Wright's Political Songs, p. 159. + +POACHED. Land is said to be poached when it is trodden with holes by heavy cattle. Var. dial. + +POACHING. Swampy. Devon. + +POAD-MILK. The first milk given by cows after calving. Sussex. + +POARE-BLIND. Dim-sighted. The word occurs in Hollyband's Dictionarie, 1593. + +POAT. To kick. Devon. + +POBS. Porridge. Craven. + +POCHE. A pocket. (A.-N.) + +Unto another she dyde as moche; + +For they love none but for theyr poche. + +The Complaynte of them that ben to late Maryed. + +POCHEE. A dish in ancient cookery consisting principally of poached eggs. Pegge. + +POCHERS. Potters? + +POCHIN. A hedgehog. Somerset. + +POCHIT. A pollard tree. Linc. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg186_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg186_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..91d72eee9df7153c1222f76109b189ba2c851f01 --- /dev/null +++ b/outputs/long_tiny_text/11_pg186_pg1_pg1_repeat1.md @@ -0,0 +1,157 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +QUERK. (1) To grunt; to moan. West. + +(2) A moulding in joinery. North. + +QUERKEN. To stifle, or choke. North. "Chekenyd or qwerkenyd," Pr. Parv. + +It will grow in the ventricle to such a masse that it will at the recelt of any hot moisture send up such an ascending fome that it will be ready to quirken and stifle us. Optick Glasse of Humors , 1639, p. 124. + +QUERN. (1) Corn. Salop. + +(2) A mill. This word is generally applied to a hand-mill. (A.-S.) " Mola , a qwernstone," Nominale MS. + +Having therefore ground eight bushels of good malt upon our querne , where the toll is saved, she addeth unto it halfe a bushell of wheat meale. Harrison's Description of England , p. 169. + +QUERPO. Same as Cuerpo , q. v. "Me must den valke in quirpo," Nabbes' Bride , 4to. Lond. 1640, sig. F. iv. + +A batt, who nigh in querpo sat, Lay snug, and heard the whole debate. Collins' Miscellanics , 1762, p. 132. + +QUERROUR. A worker in a quarry. + +QUERT. Joyful. Also, joy. In quert , joyful, in good spirits. See Lydgate , pp. 32, 38; Ritson's Met. Rom. iii. 408-9. + +Remembyr thy God while thou art quert. + +MS. Laud. 416, f. 76. + +And that hym byhoveth leve hyt in querte , And be overcome and caste to helle pytt. + +MS. Cantab. Ff. ii. 38, f. 14. + +But thouge that Noe was in quert , He was not al in ese of hert. Cursor Mundi , MS. Coll. Trin. Cantab. f. 12. + +QUEST. (1) The sides of an oven. Pies are said to be quested when their sides have been crushed by each other, or so joined to them as thence to be less baked. North. + +(2) To give tongue as hounds do on trail. "To bay or quest as a dog," Florio, p. 1. Still in use. See Forby, ii. 268. + +Kenettes questede to quelle, Al so breme so any belle, The deer daunteden In the delle, That al the downe denede. + +Reliq. Antiq. ii. 7. + +(3) An inquest. Var. dial. Both words are used by Hall, Henry VIII. ff. 50, 53. + +QUESTANT. A candidate; one who is seeking for some object. Shak. + +QUESTE. A prayer, or demand. (A.-N.) + +QUESTEROUN. Cooks, or scullions. + +QUEST-HOUSE. The chief watch-house of a parish, generally adjoining a church, where sometimes quests concerning misdemeanours and annoyances were held. The quest-house is frequently mentioned in the accounts of St. Giles, Cripplegate, 1571, MS. Addit. 12222. + +QUESTMEN. "Those that are yearly chosen, according to the custom of a parish, to assist the churchwardens in the enquiry, and presenting such offenders to the ordinary as are punishable in the court-christian," Blount's Glossographia , ed. 1681, p. 594. + +QUESTMONGER. A juryman. + +Awake, awake, ye questmongers , and take heed you give a true, just, and right verdict. + +Becon's Works , p. 370. + +QUESTUARY. Profitable. + +QUETE. Wheat. It is the translation of frumentum in MS. Lansd. 560, f. 45. + +That zere shalbe litulle quete , And plente shalbe of appuls grate. + +MS. Cantab. Ff. v. 48, f. 75. + +QUETHE. (1) Harm; mischief. (A.-S.) + +(2) To say; to declare. (A.-S.) + +(3) To bequeath. Lydgate. Hous and rente and outher thyng Mow they quethe at here endyng. + +MS. Harl. 1701, f. 42. + +(4) Cry; clamour. Gawayne. + +QUETHING. Saying, crying? Being allive and seinge I peryshe, i. beinge quycke and quethyng I am undone. + +Palsgrave's Acolastus , 1540. + +QUETHUN. Whence. Robson. + +QUETOURE. A scab, or swelling. + +QUEVER. Gay; lively. West. + +QUEW. Cold. + +QUEZZEN. To suffocate. East. + +QUHILLES. Whilst. + +Quhylles he es qwykke and in qwerte unquellyde with handsis, Be he never mo savede ne socourede with Cryste. + +Morte Arthuré, MS. Lincoln, f. 93. + +QUIB. A taunt, or mock. Coles. + +QUIBIBES. Cubebs. " Quiperium , a quybybe," Nominale MS. + +QUIBLIN. An attempt to deceive. + +QUICE. A wood-pigeon. Glouc. + +QUICHE. To move. + +QUICK. (1) Alive; living. + +In thilke time men hem tok With juggement withouten lcs, And also quic dolven hes. + +Arthur and Merlin , p. 28. + +Sir, he seid, asay of this, Thei were 3isturday quyk i-wysse. + +MS. Cantab. Ff. v. 48, f. 50. + +Quyk? ye, forsothe, quyk it was, As wel I may tel you all the case. + +The Sacrifice of Abraham , p. 18. + +(2) The growing plants which are reared or set for a hedge. Var. dial. + +(3) Sharp; piercing. Devon. + +QUICK-DEER. Deer with young. + +QUICKEN. (1) Couch grass. North. + +(2) To work with yeast. Quickening-dish , the yeast or balm that is put to new drink to make it work. North. + +(3) To revive. Still in use. + +(4) To conceive with child. + +QUICKER. A quickset hedge. West. + +QUICKLINGS. Young insects. East. + +QUICKMIRE. A quagmire. Devon. + +QUICKWOOD. Thorns. Yorksh. + +QUID. (1) The cud. Var. dial. Hence, generally, to suck one's tongue. + +(2) A mouthful of tobacco. Var. dial. + +QUIDDITY. A subtlety; a subtle quirk or pretence. Quiddit was also used. + +QUIERIE. A royal stable. + +QUIET. Gentlemanly. West. + +QUIETUS. The official discharge of an account. (Lat.) It is chiefly used metaphorically, and + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg252_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg252_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d98cd3638617b6082b7d77b4ca386f71d1453769 --- /dev/null +++ b/outputs/long_tiny_text/11_pg252_pg1_pg1_repeat1.md @@ -0,0 +1,165 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +(7) To protect; to accompany. Yorksh. + +(8) A young plant; a shoot. + +(9) Set the hare's head to the goose-giblet, i. e., tit for tat. + +(10) A gambrel. Yorksh. + +(11) To settle; to bind. Var. dial. + +(12) To place to account. (A.-S.) + +(13) The Deity is mentioned in the Towneley + +Mysteries, pp. 97, 118, as He that "sett alle on seven," i. e., set or appointed everything in seven days. A similar phrase at p. 85 is not so evident. It is explained in the glossary, "to set things in, to put them in order," but it evidently implies in some cases an exactly opposite meaning, to set in confusion, to rush to battle, as in the following examples. "To set the steven, to agree upon the time and place of meeting previous to some expedition," West. and Cumb. Dial. p. 390. These phrases may be connected with each other. Be this as it may, hence is certainly derived the phrase to be at sixes and sevens , to be in great confusion. Herod, in his anger at the Wise Men, says,— + +Bot be thay past me by, by Mahowne in heven, I shalle, and that in hy, set alle on sex and seven ; Trow ye a kyng as I wyll suffre thaym to neven Any to have mastry bot myself fulle even. + +Towneley Mysteries, p. 143. + +Thus he settez on sevene with his sekyre knyghttez. + +Morte Arthure, MS. Lincoln, f. 76. + +The duk swore by gret God of hevene, Wold my hors so evene, Yet wold I sett all one seven for Myldor the swet Degrevant, 1279. + +Old Odcoms odnesse makes not thee uneven, + +Nor carelessly set all at six and seven. + +Taylor's Workes, 1630, ii. 71. + +SETE. A city. (A.-S.) + +There ys a gyant of gret renowne, + +He dystrowythe bothe seté and towyn. + +Torrent of Portugal, p. 39. + +SETEWALE. The herb valerian, + +Fykes, relsyn, dates, + +Almaund rys, pomme-garnates, + +Kanel and setewale. + +Gy of Warwike, p. 421. + +SETH. (1) Since. (A.-S.) + +Never seth we wedyd ware, + +Therefore I make full mekyll care; + +Bot now we must per[t]e a-two, + +Do thou the best, fore I must go. + +MS. Ashmole 61, xv. Ccnt. + +(2) A scythe. Nominale MS. + +SETHE. To boil. (A.-S.) + +SET-HEDGE. A quickset hedge. East. + +SETILLE. Seat. (A.-S.) + +Fowles of heven er prowde inow that wald heghe thaire setille aboven alle other fesshe of the se. + +MS. Coll. Eton. 10, f. 13. + +Apon the setyl of hys majesté + +That day sal alle men before hym be. + +Hampole, MS. Bowes, p. 180. + +SETLINGS. Saplings. + +For such as be yet infirm and weak, and newly planted in the religion of Christ, and have taken no sure root in the same, are easily moved as young + +settings. Becon's Works, p. 18. + +SETNESSE. A decree. Hearne. + +SET-OPE. Anything by means of which a gate or door is set or kept open. + +SETS. The plaits of ruffs. + +SET-SPEECH. A speech carefully prepared and studied before it is delivered in public. + +SETTE. Ruled. Scott. + +SETTEN-ON. Short in growth. North. + +SETTER. (1) To cut the dew-lap of an ox or cow, into which helleboraster, called setter-work, being put, an issue is made for ill-humours to vent themselves. North. + +(2) An accuser. Coles. + +SETTER-GRASS. The herbear's-foot. Yorksh. Spelt setygrise in Nominale MS. + +SETTER-OUT. An editor, or author. + +SETTING. The west, so called because the quarter of the setting sun. + +SETTING-DOWN. Said of a hawk when put into the mew. Gent. Rec. ii. 63. + +SETTING-PIN. A dibble. Glouc. "Debbyll or settyng stycke," Huloet, 1552. + +SETTING-STICK. A stick used for making the plaits or sets of ruffs. + +SETTLE. (1) To fall in price. Linc. + +(2) A long seat, generally one with a long back to it. North. It is an archaism. See Setille. SETTLE-BED. A folding bed. + +SETTLE-STONES. Stones at the edge of a gutter in a cow-house. North. + +SEU. Suit. Hearne. + +SEUGH. A wet ditch; a drain. North. "The towne sinke, the common sew," Nomenclator, 1585, p. 391. + +SEUNE. Seven. Cumb. + +SEUREMENT. Security, generally used in the legal sense. (A.-N.) + +SEURETEE. Certainty. (A.-N.) + +SEVEN-NIGHT. A week. This word occurs in The French Alphabet, 1615, p. 18. + +He levyth not oon sevenyghte. + +MS. Cantab. Ff. ii. 38, f. 63. + +SEVEN-YEAR. "Has been a vile thief this seven year," Shakespeare. It was a proverbial expression for a long time . + +O, the body of a Gorge, + +I wold I had them heare ; + +In faith, I wold chope them, + +Thay ware not so hack this seven yeere ! + +Marriage of Witt and Wisdome, 1579. + +I can then thanke Sensuall Apetyte: That is the best daunce without a pype That I saw this seven yere. + +Interlude of the Four Elements, n. d. + +SEVERALS. Portions of common assigned for a term to a particular proprietor, the other commoners waiving for the time their right of common over them. See Hunter on Shakespeare, i. 267. + +SEVERY. A division or compartment of a vaulted ceiling. "Severous of a howse," MS. Dictionary, 1540. + +SEW. (1) Same as Assue, q. v. + +(2) Sowed. Linc. + +(3) To wipe the beak, a term in ancient hawking given by Berners. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg36_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg36_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f5d161a94e8d3fe83430436e77f2f9ee82d1a98f --- /dev/null +++ b/outputs/long_tiny_text/11_pg36_pg1_pg1_repeat1.md @@ -0,0 +1,161 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Who lukes to the lefte syde, whenne his horse launches . With the lyghte of the sonne men myghte see his lyere. Morte Arthure, MS. Lincoln, f. 80. + +LAUNDE. A plain place in a wood; an unploughed plain; a park; a lawn. "Saltus, a lawnd," Nominale MS. + +Now is Gij to a launde y-go, Wher the dragoun duelled tho. + +Gy of Warwick, p. 262. + +For to hunt at the hartes in thas hye laundes In Glamorgane with glee, thare gladchipe was evere. Morte Arthure, MS. Lincoln, f. 53. + +LAUNDER. (1) Any kind of gutter or channel for conveying water. Var. dial. + +(2) A washer. Also, to wash. "Buandière, launderer." Hollyband's Dictionarie, 1593. Laundring gold, washing it. + +LAUNDRE. A laundress. Palsgrave. + +LAUP. To leap. Yorksh. + +LAUREAT. Crowned with laurel. (Lat.) The laureatship at our universities was a degree in grammar, including poetry and rhetoric, so called because the person who graduated was presented with a wreath of laurel. + +LAUREOLE. Spurge-laurel. (A.-N.) + +LAURER. A laurel. Chaucer. + +LAUS. Loose. (A.-S.) + +LAUTER. The laurel. (A.-N.) + +That worthy was the lauter to have Of poetrie, and the palme to atteyne. + +Lydgate, MS. Ashmole 39, f. 48. + +LAU3T. Caught; received. (A.-S.) + +Thenne was Marie Joseph bitaugt, And he hir in spousaile laugt. + +Cursor Mundi, MS. Coll. Trin. Cantab. f. 67. + +LAVALTOE. Same as Lavolta, q. v. + +For lo! the liveless Jacks lavaltoes take At that sweet musick which themselves do make. + +Brome's Songs, ed. 1661, p. 133. + +LAVANDRE. A laundress. "A tretise for lavandres," Reliq. Antiq. i. 26. + +LAVANT. A land-spring. South. + +LAVAS. Lavish. Romeus and Juliet, p. 20. + +LAVAST. Uninclosed stubble. Kent. + +LAVE. (1) The rest; the remainder. North. + +(2) To lade or draw water. Chaucer. Also, to pour, as in Perceval, 2250; to wash, Piers Ploughman, p. 273. + +(3) To gutter, as a candle. Wilts. + +(4) To hang, or flap down. Hall. + +LAVE-EARED. Long, or flap-eared. See Topsell's Beasts, p. 366; Hawkins, iii. 357; Lavelugged, Northumb. Holloway has lapped in use in Sussex and Hants. + +LAVEER. To work a ship against the wind. An old sea term. + +LAVELL. The flap that covers the top of the windpipe. Still used in Devon. + +LAVENDER. To lay in lavender , to pawn. This is a very common phrase in old plays. "To lay to pawne, as we say to lay in lavander," Florio, p. 27. + +LAVENDREY. Washing. (A.-N.) + +LAVER. (1) The remainder. North. + +(2) A cistern, trough, or conduit, to wash in. "Laver to washe at, lavoyr," Palsgrave. Also, a basin. See Florio, p. 89; Cotgrave, in v. + +Esgunere; Leg. Cathol. p. 154; Reliq. Antiq. i. 7; Davies' Ancient Rites, 1672, p. 130. And fulle glad, certys, thou schalt bee, Yf that y wylle suffer the To holde me a labour and bason to my honde. + +MS. Cantab. Ff. ii. 38, f. 144. + +(3) A dish composed of a kind of sea-weed well washed and boiled. It is also called laver-bread, Kennett, MS. Lansd. 1033. + +(4) Laver lip, a hanging lip. + +LAVERD. Lord. (A.-S.) + +That tay after thaym ne went To du thayr laverd comandement. + +Guy of Warwick, Middlehill MS. + +LAVEROCK. The lark. North. See Wright's Lyric Poetry, pp. 26, 40; Reliq. Antiq. i. 86; Wright's Purgatory, p. 55; laverkes , Beves of Hamtoun, p. 138. + +Sche made many a wondir soune, + +Sumtyme liche unto the cok, + +Sumtyme unto the laverok. + +Gower, MS. Soc. Antiq. 134, f. 152. + +Tyrlery lorpyn, the laverocke songe, So meryly pypes the sparrow; The cow brake lose, the rope ran home, Syr, God gyve yow good morow. + +Bliss's Bibl. Miscell. p. 54. + +LAVISH. Rank, as grass, &c. West. + +LA-VOLTA. A kind of very active bouncing waltz, formerly much in fashion. The man turned the woman round several times, and then assisted her in making a high spring. + +Leave protestations now, and let us hie + +To tread lavolta , that is women's walk. + +Soliman and Perseda, p. 214. + +LAVY. Lavish; liberal. North. + +LAW. (1) To give a hare good law, i. e. a good start before the hounds. It is in very frequent use by boys at play. + +(2) A hill, or eminence. North. + +(3) Custom; manner. See Ellis, ii. 335. + +(4) Low. North. + +He wist not that hym was gode, But then he putte doune his hode On knees he fel downe lawe. + +MS. Cantab. Ff. v. 48, f. 55. + +I.AWAND. Bowing; humbling. + +Anely lawand thameselfe to the sacramentes of haly kyrke, thof it be swa that thay hafe bene cumbyrde in syne and with syne alle thaire lyfe tyme. MS. Lincoln A. i. 17, f. 229. + +LAWE. (1) To laugh. Nominale MS. + +(2) Rough; violent; brutal. West. + +LAWED. Ignorant. See Laird. + +LAWES. The same as Kairns , q. v. + +LAWESTE. The lowest. North. + +Lenges all at laysere, and lokes one the wallys Whare they ware laweste the ledes to assaille. + +Morte Arthure, MS. Lincoln, f. 79. + +LAWFUL-CASE. An interj. of surprise. + +LAWGHE. Low. Hampole. + +LAWING. (1) Going to law. Linc. + +(2) Lawing of dogs, i. e. cutting out the balls, or three claws of the fore-feet. + +LAWLESS-MAN. An outlaw. (A.-S.) + +LAWN. The same as Launde , q. v. + +LAWNDER. The sliding iron in the fore-part of a plough. Var. dial. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg375_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg375_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fddffdc868d6e1649a7f1835f2acc1167716b444 --- /dev/null +++ b/outputs/long_tiny_text/11_pg375_pg1_pg1_repeat1.md @@ -0,0 +1,89 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +When many a taylers boy I know hath beene, Hath made tall men much feareful to be seene. Taylor's Workes , 1630, iii. 73. + +TAILORS-MENSE. A small portion left by way of good manners. See Brockett. + +TAILOURS. A book of ancient cookery receipts thus describes the way of making taylours : + +Take aimondes, and grynde hem raw in a morter, and temper hit with wyne and a litul water, and drawe it thorgh a streynour into a goode stiff mylke into a potte, and caste thereto reysons of coraunce and grete reysons my[n]ced, dates, clowes, maces, pouder of peper, canel, saffrone a good quantité, and salt, and sette hem over the fire, and iete al boyle to-gidre a while, and alay hit up with floure of ryse or elles grated brede, and cast thereto sugur and salt, and serve hit forth in maner of mortrewes, and caste thereone pouder ginger in the dissh. + +MS. Harl. 4016, f. 19. + +TAIL-PIPING. Tying a tin can or anything to the tail of a dog, which is generally done to prevent his paying visits to the place where this punishment may be inflicted. + +TAIL-ROPE. Part of a horse's harness, mentioned in MS. Coll. Jes. Oxon. 28. + +TAIL-SHOTEN. A disease in the tail of cattle, in which the spinal marrow is so affected that in a short time the beast is unable to stand. Also called tail-soke . + +TAIL-TOP. The swingle of a flail. + +TAILSOR. A tailor. Nominale MS. + +TAINCT. A kind of red-coloured spider very common in the summer time. + +TAINT. (1) A term at tilting, apparently meaning to injure a lance without breaking it. Gifford, Ben Jonson, ii. 55, explains it, to break a staff, but not in the most honorable or scientific manner. Sec, however, the second example under Attaint . + +(2) Explained in the Booke of Hawking, "a thing that goeth overthwart the feathers of the wings and of the tail, like as it were eaten with worms." + +(3) A dirty slattern. East . + +(4) Explained by Forby, "a large protuberance at the top of a pollard tree." + +(5) "A taint or overreach in the backe or shanke of a horse," Florio, p. 47. + +TAINTERS. + +For the outward compound remedies, a plaister made of opponax and pitch is much commended, which Menippus used, taking a pound of pitch of Brutias, and foure ounces of opponax (as Ætius and Actuarius doe prescribe) adding withall, that the opponax must be dissolved in vinegar, and afterward the pitch and that vinegar must be boyled together, and when the vinegar is consumed, then put in the opponax, and of both together make like taynters or splints and thurst them into the wound, so let them remaine many dayes together, and in the meane time drinke an antidot of sea-crabs and vinegar, (for vinegar is always pretious in this confection). + +Topsell's Four-Footed Beasts , 1607, p. 187. + +TAISAND. Poising ready for throwing. + +And ther biside, on o donjoun, + +He kest a man of cler latoun, + +And in his hond an arblast heldand, + +And therinne a quarel taisand . + +Sevyn Sages, 1978. + +TAISHES. Taces, armour for the thighs. This form of the word occurs in Warner's Albion's England, xii. p. 291. + +TAISTREL. A rascal; a villain. North . + +TAIT. (1) The top of a hill. West . + +(2) To play at see-saw. Dorset . + +TAKE. (1) To give; to deliver up to. (A.-S.) + +And alle that they aske scho wylle them take , For drede of theym, swyike boste they make. + +MS. Harl. 2260, f. 59. + +But take hur an oolde stede, And an olde knygt that may hur lede, + +Tylle sche be paste yowre realme, + +And gyf them some spendynge, + +That them owt of thy londe may brynge, + +Y can no bettyr deme. + +MS. Cantab. Ff. ii. 38, f. 72. + +(2) A vulgar name for the sciatica, mentioned in Aubrey's MS. Nat. Hist. Wilts, p. 10, in the library of the Royal Society. + +(3) A sudden illness. Dorset . + +(4) A lease. North . + +(5) "I take the wynde, as a dere dothe of a person, je assens," Palsgrave. + +(6) To take up, to reprove. "Tanser, to chide, rebuke, checke, taunt, reprove, take up," Cotgrave. To take up a horse , to make him gambol. To take on, to take by, to be much affected by any melancholy event. To take in, to capture, to subdue. To take one along, to take one with you, to go no faster than he can go with you, i. e. to let him understand you. To take out, to copy. To take one's teeth to anything, to set about it heartily. To take a stick to one, to beat him. To take on, to enlist for a soldier. To take to do, to take to task, to take a talking to, to reprove. To take on, to simulate. To take after, to resemble. To take off, to mimic, to ridicule. To take to, to capture, or seize; to attack. Also, to marry; to enter on a farm; to own, or acknowledge. To take shame, to be ashamed. To take up for any one, to give surety, to protect. To take on, to associate with. A take-away, an appetite. To take one's ease in one's inn, to enjoy one's self, as if at home. To take up, to borrow money, or take commodities upon trust. To take up a quarrel , to settle or make it up. To take upon, to suspect any one of a wrong action. To take forth, to learn, to teach. To take order for, to provide for or against anything. To take to anything, to answer for the truth of it; to stand to a bargain. To take up, to clear up, said of the weather. Also, to reform one's habits; to commence anything. To take clothes about one, to wrap them well over him. To take about the neck, to embrace. To take a breath, to consider well beforehand or take advice. To take any one forth, to set him forwards. To take heart, to take courage. To take one's part, to defend him. To take in worth, to take in good part, to take anything kindly or friendly. To take to one's legs, to fly. To take a horse with the spurs, to spur him onwards. To take on with one's + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg377_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg377_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..694af702432b746371f2c36fdb95da58eb1e6073 --- /dev/null +++ b/outputs/long_tiny_text/11_pg377_pg1_pg1_repeat1.md @@ -0,0 +1,165 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +TALISHE. Fabulous. This word occurs in Palsgrave's Acolastus, 4to. 1540. + +TALL. (1) Explained by Junius, "obedient, obsequious, every way flexible." See the Glossary to Urry's Chaucer, p. 81. + +(2) Valiant; bold; fine; great. This is a very common word in old plays. + +They leaping overboord amidst the billowes, We pluck'd her up (unsunke) like stout tall fellows. Taylor's Workes, 1630, ii. 23. + +TALL-BOYS. High cups or glasses. Grose says, bottles or two-quart pots. + +TALLE. To mock. (A.-S.) + +Unarmed were the paiens alle, + +Our folk hem gun to talle. + +Arthur and Merlin, p. 257. + +TALLEE. "When they hale aft the sheate of maine or fore-sailes, they say, Tallee aft the sheate," MS. Harl. 6268. Taylia, Reliq. Antiq. i. 2. + +TALLICHE. The same as Tally (6). + +TALLIT. A hayloft. West. "When the prisoner came in he was watcherd, which shewed he had not been all night in the tallit." + +TALL-MEN. Dice so loaded as to come up with high numbers. A cant term. + +TALLOW-CAKE. A cake of tallow; tallow made up in the form of a cake. Var. dial. + +TALLOW-CATCH. Same as Keech (2). + +TALLOW-CRAPS. See Craps (1). + +TALLOW-HUED. Pale as tallow. North. Burton uses the phrase tallow-faced. + +TALLOW-LAFE. Congiarium, MS. Dict. c. 1500. + +TALL-WOOD. "Tall woode, pacte wodde to make byllettes of, taillee," Palsgrave. The term is still used in Kent. + +TALLY. (1) A term in playing ball, when the number of aces on both sides is equal. North. + +(2) To reckon. See Becon's Works, p. 134. + +(3) In counting any articles which are sold by the hundred, one is thrown out after each hundred; that is called the tally . The number of tallies of course shows the number of hundreds. They are given in to the purchaser. Hunter. + +(4) A kind of small ship. + +(5) A company or division of voters at an election. Somerset. + +(6) Stoutly; boldly. + +(7) Seemly; decently; elegantly. + +TALME. To become dumb? + +Hur fadur nere-hande can talme, Soche a sweme hys harte can swalme. + +Le Bone Florence of Rome, 769. + +I donke upon David. til mi tonge talmes : I ne rendrede nowt. sithen men beren palmes : Is it also mikel sorwe. in song so is in salmes ? + +Reliq. Antiq. i. 292. + +TALSHIDES. "One pound of white lights, ten talshides, eight faggotts," Ord. and Reg. p. 162. + +TALT. Pitched. + +There was talt many pavyloun + +Of riche sendel and siclatoun. + +Kyng Alisaunder, 5234. + +TALVACE. A kind of buckler or shield, bent on each side, and rising in the middle. + +Aither bright unto the place + +A mikel rownd talvace. + +Ywaine and Gawin, 3158. + +And after mete thar it was, + +The children pleide at the talvas. + +Beves of Hamtoun, p. 145. + +TALWHE. Tallow. Nominale MS. + +TAM. The abbr. of pr. n. Thomasine. + +TAMARA. A compound of spices. + +TAME. (1) To broach or taste liquor. "To tame, tap, dolium relinere," Coles. + +Nowe to weete our mouthes tyme were, + +This flagette will I tame, yf thou reade us. + +Chester Plays, i. 124. + +(2) To cut; to divide. West. + +TAME-GOOSE. A foolish fellow. "I say cast away; yea, utterly cast away upon a noddy, a ninny-hammer, a tame-goose," The Case is Altered, 4to. Lond. 1605. + +TAMER. A team of horses. Norf. + +TAMINE. A sort of woollen cloth. + +TAMLIN. A miner's tool. Cornw. + +TAMMY. Glutinous, or sizy. Cumb. + +TAMPIN. A long pellet. + +Make two stiffe long rowles or tampins of linnen clowtes, or such like stuffe, sharpe pointed like sugar-loves; which tampins are called of the physicians in Latine pessi , and being annointed with the ointment aforesaid, thrust them up into the horsses nostrils, and let them abide therein a pretty whilk; then pul them out, and you shal see such abundance of matter come forth at his nose as is marvellous to behold. + +Topsell's Four-Footed Beasts, 1607, p. 372. + +TAMPING-IRON. A tool used for beating down the earthy substance in the charge used for blasting. Cornw. + +TAMPION. A piece of wood fitted to the mouth of a large gun. "Tampyon for a gon, tampon," Palsgrave, subst. f. 69. + +Unadvisedly gave fire to a pece charged with a pellet insteade of a tampon , the which lighting on the palaice wall, ranne through one of the privie lodgings, and dld no further harme. + +Lambardes Perambulation, 1596, p. 433. + +TAN. (1) Taken. (A.-S.) + +When pese was cried and day tan , + +Kyng Ardus was a yoyfulle man. + +MS. Cantab. Ff. ii. 38, f. 78. + +Baptem the first is holden than, That falleth at the fonte be tan. + +MS. Sloan. 1785, f. 34. + +(2) To entice. (A.-S.) + +The fende of helle agayn skylle + +Put in hir a harde wille + +Hur fadur luf to wyne ; + +And also tempered was that man + +His owne doucter for to tan , + +To do a dedly synne. + +MS. Cantab. Ff. v. 48, f. 43. + +(3) Then. Var. dial. + +(4) To dun. (5) To beat. Var. dial. + +(6) A twig, or small switch. Lane. + +TANACLES. A kind of pincers, used formerly for torturing. "To pinch or tanacle with tongs, with pincers or tanacles," Florio, p. 552, ed. 1611. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg418_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg418_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3559633309d7c4e5d8afa69ad146debae61a48d8 --- /dev/null +++ b/outputs/long_tiny_text/11_pg418_pg1_pg1_repeat1.md @@ -0,0 +1,153 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +and the yarn is pressed by the hand of the spinner. Forby. + +(2) The skinny part of roasted meat, which before the whole can be dressed becomes tough and dry, like a trip overkept, or the leather used by the old woman. Forby. + +TRISE. To pull up. + +TRISTE. (1) + +Hast thou be prowde and eke of port For tryste of lady and eke of lord. MS. Cott. Claud. A. ii. f. 140. + +(2) To trust. + +I was in prison wel ye wist, To helpe of you ne myght I triste. MS. Addit. 11305, f. 90. My lorde, when he went to the see, For specyalle tryste he toke me to the. MS. Cantab. Ff. ii. 38, f. 72. + +(3) A post or station in hunting. I se huntynge, I se hornes blow, Houndes renne, the dere drawe adowne, And atte her triste bowes set arow, Now in August this lusti fressh cesone. MS. Cantab. Ff. i. 6, f. 13. + +(4) A trestle, or support. + +(5) A windlass. + +(6) A cattle-market. North . + +TRISTER. See Triste (3). + +TRISTESCE. Sadness. + +Save only that I crye and bidde, I am in tristesce alle amidde. Gower, MS. Soc. Antiq. 134, f. 126. + +TRISTILY. Safely; securely. "Qwhenne they tristily had tretyd," Morte Arthure, MS. Lincoln, f. 57. + +TRISTIVE. Sad. (Lat.) + +TRISTUR. The same as Triste (3). + +TRIUMPH. (1) A public show. + +(2) A trump at cards. (Fr.) The game of trump was also so called. + +TRIVANT. A truant; a loiterer. + +TRIVET. Right as a trivet, perfectly right. A common phrase. + +TRIVIGANT. Termagant. (Ital.) + +TRIWEDE. Honesty. Hearne. + +TROACHER. A dealer in smuggled goods. + +TROANT. A foolish fellow. Exm. + +TROAT. To bellow, said of the buck. + +TROCHE. To branch. (A.-N.) + +TROCHES. Were thus made: + +Take of Benjamin six ounces, wood of aloes eight ounces, styrax-calamite three ounces, musk half a dram, orrice two ounces, sugar-candy three pound; powder them, and with rose-water make troches. Cosmeticks, 1660, p. 138. + +TROCHINGS. The cluster of small branches at the top of a stag's horn. + +TROD. A footpath. Linc. "Ran from trod to trod," Du Bartas, p. 360. + +TRODE. Track; path. (A.-S.) + +Yf thou ever trowyde ore undyrstode That thl wytt ore thl gude Commys of thiselfe and noyte of Gode, That es grett pryde and fals trode. R. de Brunne, MS. Bowes, p. 16. + +TRODUS. Steps. + +They nyste never wher he was a-go, Ne of his trodus no sygne ther nasse. Chron. Vilodun. p. 15. + +TROEN. + +Peny rydys troen be troen, Ovyr all in ylke a toen, On land and eke on flode. + +Reliq. Antiq. ii. 110. + +TROFELYTE. Ornamented with knots. Gaw. TROGH. A tree. + +TROGHTE. Belief? + +The thryde es for-thy that we have Alle o troghte that sal us save. + +MS. Harl. 2260, f. 21. + +TROIFLARDES. Trifers; idlers. + +TROITE. The cuttle-fish? "Sepia, Anglice a troite," Nominale MS. + +TROJAN. A boon companion; a person who is fond of liquor. A cant term. According to some, a thief was so called; but it was applied somewhat indiscriminately. A rough manly boy is now termed "a fine Trojan." Grose has trusty Trojan , a true friend. + +TROKE. (1) To barter; to truck. North . + +(2) To fall short. He mone stond faste thereby, Or ellys hys schote wolle troke . + +MS. Porkington 10, f. 58 + +TROKES. Square pieces of wood at the tops of masts to put the flag-staffs in. + +TROLL. To trundle. To troll the bowl , to pass the vessel about in drinking. + +TROLLEN. To draw; to drag. (A.-S.) + +TROLL-MADAM. A game borrowed from the French in the 16th century, now known under the name of trunks , q. v. Brand quotes a curious account of this game, from which it appears to have formed a favorite indoor amusement with the lady fashionables at Buxton about the year 1572, and to have been somewhat like the modern game of bagatelle . There is an allusion to it in the Winter's Tale, iv. 2. + +TROLLOP. (1) A slattern. Var. dial. + +(2) A string of horses. Linc . + +TROLLOPISH. Filthy; dirty. South . + +TROLLY. A low heavy cart. Var. dial. + +TROLLYBAGS. Tripe. Var. dial. + +TROLLY-LOLLY. Coarse lace. + +TROLUBBER. A hedger and ditcher. Devon. + +TROME. Band, or company. (A.-S.) + +TOMPE. (1) A trumpet. (A.-N.) + +(2) A shin, or shank. + +TROMPOUR. A trumpeter. + +TRONAGE. A toll for the weighing of wool in the market. Coles . + +TRONCHEON. A scab. + +TRONCHON. A fragment. (A.-N.) + +Upon a tronchon of a spere, He set the hed of the bore. + +MS. Cantab. Ff. ii. 38, f. 100. + +TRONE. (1) A throne. (A.-N.) It is the verb, to enthrone, in this example. + +And ther soulys to hewyn bere, Before God tronyd they were. + +MS. Cantab. Ff. ii. 38, f. 38. + +(2) A ridge of mown hay. West . + +(3) A post, or log of wood. + +TRONES. A steelyard. North . + +TRONSOUN. A club, or staff. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg421_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg421_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9e345a6dd58b4af7a5001981419f3d35625b616c --- /dev/null +++ b/outputs/long_tiny_text/11_pg421_pg1_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +TRUNK-WEAM. A fiddle. TRUNLIN. A large coal. North. TRUNNLE. The same as Trendle, q. v. TRUNTLEMENT. Trumpery. North. TRUPHILLE. A trifle. TRUSH. (1) A hassock. Kent. (2) To trush about, to litter. (3) To run about in the dirt. North. TRUSLE. (1) Trust. Weber. (2) To wrap up; to get ready. TRUSS. (1) A padded jacket worn under the armour to protect the skin. (2) To tie the points of hose. To truss up, to tuck up the gown, &c. (3) The baggage of an army. (4) To pack up. Hence, to make ready. And trusse al that he mithen fynde Of hise, in arke, or in klste. Havelok, 2018. (5) A boy's game, like leap-frog. (6) Truss up, to hang a person. TRUSSEL. (1) A pack, or bundle. (2) A stand for a barrel. Kent. TRUSSES. The same as Trouses, q. v. TRUSSING. In falconry, is a hawk's raising any fowl or prey aloft; soaring up, and then descending with it to the ground. TRUSSING-BASKET. A basket used for conveying large parcels of goods. Called also a trussing-coffer. TRUSSING-BED. A travelling bed. "Trussyng bedde, lit de champ," Palsgrave. Also my large bed of black velvet, embroidered with a circle of fetter-locks, and garters, all the beds made for my body called in England trussing-beds . Test. Vetust. p. 141. TRUT. (1) Stercus. Hearne. (2) The cry of hunters returning home after the sport is finished. TRUTHY. Faithful; veracious. East. TRY. (1) To fare. Somerset. (2) A corn screen. Also, to screen. (3) To boil down lard. East. (4) How de try, how do you do? Exm. (5) A club tipped with iron. TRYALYTES. Three benefices united. TRYERS. And shew'd themselves as errant lyars, As th' were 'prentice to the tryers . Brome's Songs, 1661, p. 167. TRYSTI. Trusty; secure. On trysti roche heo stondeth fast, And wyth depe dyche buth all be cast. Religious Poems, xv. Cent. TRYVE. To drive. In chastlsynge hath made a rod To tryve awey hire wantonnesse. Gower, MS. Soc. Antiq. 134, f. 111. TU. To work hard. North. TUARN. The place in an iron furnace which receives the metal. Staff. TUAY. Two. From arnemorwe to the midday, He hadde strengthe of knightes tuay . Arthur and Merlin, p. 178. TUB. (1) Tale of a tub, a stupid nonsensical story. + +(2) The top of a malt-kiln. Essex. (3) The gurnet. Cornw. (4) One mode of curing the lues venerea was by the tub, the patient sweating for a considerable time in a heated tub. This mode is often alluded to by early writers. TUBBAN. A clod of earth. Cornw. TUBBER. A cooper. North. TUBBLE. A mattock. Devon. TUB-IRON. An iron placed in front of a smith's fire-place, having a hole through which the spout of the bellows is put. TUBLE. Earthenware. West. TU-BRUGGE. A drawbridge. TUCK. (1) To eat. Also, an appetite. (2) A short pinafore. East. (3) To smart with pain. Wilts. In Devonshire, to pinch severely. (4) A slap. Devon. (5) A horizontal fold made in a garment to accommodate it to the height of a growing person. (6) To touch. Somerset. (7) A rapier. Still in use. (8) To chuck. Cornw. TUCKER. (1) A fuller. West. (2) The same as Pinner, q. v. TUCKER-IN. A chambermaid. West. TUCKET. A slight flourish on a trumpet. TUCKING. A bag used for carrying beans in when setting them. Glouc. TUCKING-GIRDLE. "Tuckyng kyrdell, saincture decourser," Palsgrave. TUCKS. Iron pins in the frame of a timber-tug to prevent the timber slipping off. TUCKSHELLS. Tusks. Sussex. TUE. (1) To rumple. North. (2) The same as Tew, q. v. TUEL. (1) A towel. West. (2) The fundament. See Tewel. (3) A vexatious meddling. North. TUEN. To go. Ant alle the other that mine buen, Shule to blisse with me tuen . Harrowing of Hell, p. 29. TUFF. (1) A Turkish turban. (2) A tassel. Also, to ornament with tassels. (3) A lock of wool. (4) To spit or hiss, as a cat. TUFFOLD. A small outhouse. Yorksh. TUFT: A grove, or plantation. TUFT-HUNTER. A hanger-on to noblemen and persons of quality. TUFT-MOCKADO. A mixed stuff-made to imitate tufted taffeta, or velvet. TUFT-TAFFATY. A taffaty tufted, or left with a nap on it, like velvet. Sleeveless his jerkin was, and it had been Velvet, but 'twas now (so much ground was seen) Become tufftaffaty; and our children shall See it plain rash a while, then nought at all. Donne's Poems, p. 129. TUG. (1) A contest. Var. dial. (2) A timber-carriage. Sussex. (3) To rob; to spoil. North. (4) A difficult undertaking. West. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/11_pg57_pg1_pg1_repeat1.md b/outputs/long_tiny_text/11_pg57_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f48dfc06dd50a2ce83ec9203eeff9d53b321a0a3 --- /dev/null +++ b/outputs/long_tiny_text/11_pg57_pg1_pg1_repeat1.md @@ -0,0 +1,161 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +(4) The privilege of turning out cattle on commons. North . + +LOOT. A thin oblong square board fixed to a staff or handle, used in boiling brine to remove the scum. Staff . + +LOOTH. The same as Loo , q. v. + +LOOVER. An opening at the top of a dove-cote. North. See Lover (2). + +LOOVEYD. Praised. Ritson . + +LOOVEYNG. Praise; honour. + +That was a feyre tokenynge Of pees and of looveyng. + +MS. Cantab. Ff. ii. 38, f. 162. + +LOOZE. A pig-stye. West . + +LOOZ. Laughed. "At hym ful fast thei loo," MS. Cantab. Ff. v. 48, f. 53. + +LOP. (1) A flea. North . (A.-S.) + +Ys joy y-now so ye your lyggys streyne, Ye lade longe-sydyde as a loppe. + +MS. Fairfax 16. + +(2) To lollop or lounge about. Kent . + +(3) To hang loosely; to hang down, or droop. Var. dial. + +(4) The faggot wood of a tree. + +LOPE. Leapt. Also, to leap. It seems to be a subst. in the second example. + +As sone as the chylde had spoke, The fende ynto hym was lope. + +MS. Harl. 1701, f. 40. + +Tyme goth fast, it is full lyght of lope. And in abydyng men seyn ther lyghte hope. + +MS. Rawl. Poet. 118. + +LOP-EARED. Having long pendentous ears like a hound. Var. dial. + +LOPEN. Leapt. See the Sevyn Sages, 739. + +Whan thy mouthe with shryfte ys opun Deth and synne are bothe oute lopun. + +MS. Harl. 1701, f. 79. + +The portar set the yatys opon, And with that Befyse ys owt lopon. + +MS. Cantab. Ff. ii. 38, f. 108. + +Anoon was al that feire gederynge Lopen undir oure lordes wynge. + +Cursor Mundi , MS. Coll. Trin. Cantab. f. 111. Sythen he ys lopen on hys stede, He with hym Harrawde dud lede. + +MS. Cantab. Ff. ii. 38, f. 154. + +LOPE-STAFF. A leaping-staff. "A lope-staffe wherewith men leape ditches," Cotgrave. + +LOPIRD. Coagulated. Still in use. See Forby, Brockett, Grose, Kennett, &c. + +Thare he fande none other fode, Bot wlatsome glete and lopird blode + +MS. Lincoln A. i. 17, f. 276. + +Thare dwelled a man in a myrke donjowne, And in a fowle stede of corrupcyowne, + +Whare he had no fode, + +Bot wlatsome glette and lopyrd blode. + +Hampole, MS. Bowes , p. 25. + +LOP-LOACH. The leech used by surgeons for drawing blood. North . + +LOPLOLLY. A lazy fellow. West . + +LOPPING. Lame. Dorset . + +LOP-SIDED. One-sided. Var. dial. + +LOP-START. The stoat. East . It is mentioned in Harrison's England, p. 230. + +LOPUSTER. A lobster. + +LOPWEBBE. A spider's web. (A.-S.) + +As a lopnebble fileth fome and gnattis, Taken and suffren gret files go. + +Occleve, MS. Soc. Antiq. 134, f. 267. + +LOQUINTUE. Eloquent. Weber . + +LORD. (1) A title of honour given to monks and persons of superior rank. (A.-S.) + +(2) Lord have mercy upon us was formerly the inscription on houses infected with the plague. Lord have mercy upon me , a disease thus mentioned in the Nomenclator, "the Illiake passion, or a paine and wringing in the small guts, which the homelier sort of physicians doe call, Lorde have mercy upon me ." + +LORDEYN. See Fever-Lurden . "The lurgy-fever, idleness," Craven Glossary, p. 304. + +I trow he was infecte certeyn + +With the faitour, or the fever lordeyn. + +MS. Rawl. C. 86, xv. Cent. + +LORD-FEST. Excessively lordly. (A.-S.) + +LORDINGS. Sirs; masters. (A.-S.) It is often used by later writers in contempt. + +LORD-OF-MISRULE. The person who presided over the Christmas revels, by no means an unimportant personage in the olden times. He began his rule on All-hallow eve and continued it till Candlemas day. See a list of expences, dated in 1552, in Kempe's Loseley Manuscripts, pp. 44-54. For further information on the subject, see Brand, i. 272; Arch. xviii, 313-335; Hawkins' Engl. Dram. iii. 156; Strutt, ii. 200; Lilly's Sixe Court Comedies, 12mo. 1632, sig. F. + +LORDS-AND-LADIES. See Bulls-and-Cows . + +LORDSHIP. Supreme power. (A.-S.) + +LORD-SIZE. The judge at the assizes. + +LORD'S-ROOM. The stage-box in a theatre was formerly so called. Jonson . + +LORDSWYK. A traitor. Ritson . + +LORE. (1) Knowledge; doctrine; advice. (A.-S.) + +(2) Lost. Still in use in Somerset. The kyng seld, Take me thy tayle, For my hors I wolde not the fayle, A peny that thou lore . + +MS. Cantab. Ff. v. 48, f. 51. + +LOREFADYR. A teacher. Loremastir , Dial. Creat. Moral. p. 243. + +Of al men they do most evyl, + +Here lorefadyr ys the devyl. MS. Harl. 1701, f 24, LOREINE. A rein. See Launfal, 888. + +Hys loreine lemyd alle with pride, Stede and armure alle was blake. + +MS. Harl. 2252, f. 104. + +LOREL. A bad worthless fellow. (A.-N.) Lorels den , Holinshed, Chron. Ireland, p. 93. Cocke Lorel was formerly a generic title for a very great rascal. "Lasy lorrels," Harman, 1567. + +LOREMAR. A bit-maker. Palsgrave. "Lori- mers or bit-makers," Harrison, p. 97. + +LORENGE. Iron. (A.-N.) + +LORER. The laurel-tree. Chaucer . + +This Daphne into a lorer tre + +Was turnid, whiche is ever grene. + +Gower, MS. Soc. Antiq. 134, f. 95. + +And plaunted trees that were to preise, Of cldre, palme, and of loreve . + +Cursor Mundi, MS. Coll. Trin. Cantab. f. 52. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/12_pg174_pg1_pg1_repeat1.md b/outputs/long_tiny_text/12_pg174_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..354c2c48e7c206f17ea102bdce1a46b3a27455be --- /dev/null +++ b/outputs/long_tiny_text/12_pg174_pg1_pg1_repeat1.md @@ -0,0 +1,111 @@ +Cohan, F.M., 1994. The effects of rare but promiscuous genetic exchange on evolutionary divergence in prokaryotes. American Naturalist 143, 965–986. + +Cohan, F.M., 2005. Periodic selection and ecological diversity in bacteria. In: Nurminsky, D. (Ed.), Selective Sweep. Georgetown, TX: Landes Bioscience. + +Cohan, F.M., 2010. Synthetic biology: Now that we're creators, what should we create? Current Biology 20, R675–R677. + +Cohan, F.M., 2011. Are species cohesive?−A view from bacteriology. In: Walk, S., Feng, P. (Eds.), Bacterial Population Genetics: A Tribute to Thomas S. Whittam. Washington, DC: American Society for Microbiology Press. + +Cohan, F.M., 2013. Species. In: Maloy, S., Hughes, K. (Eds.), Brenner's Encyclopedia of Genetics, second ed. Amsterdam: Elsevier. + +Cohan, F.M., 2016. Bacterial speciation: Genetic sweeps in bacterial species. Current Biology 26, R112–R115. + +Cohan, F.M., Aracena, S., 2012. Prokaryotic sex: Eukaryote-like qualities of recombination in an Archaean lineage. Current Biology 22, R601–R602. + +Cohan, F.M., Koeppel, A.F., 2008. The origins of ecological diversity in prokaryotes. Current Biology 18, R1024–R1034. + +Cohan, F.M., Perry, E.B., 2007. A systematics for discovering the fundamental units of bacterial diversity. Current Biology 17, R373–R386. + +Connor, N., Sikorski, J., Rooney, A.P., et al., 2010. The ecology of speciation in Bacillus. Applied and Environmental Microbiology 76, 1349–1358. + +Corander, J., Marttinen, P., Siren, J., Tang, J., 2008. Enhanced Bayesian modelling in BAPS software for learning genetic structures of populations. BMC Bioinformatics 9, 539. + +Cordero, O.X., Polz, M.F., 2014. Explaining microbial genomic diversity in light of evolutionary ecology. Nature Reviews. Microbiology 12, 263–273. + +Coyne, J.A., Orr, H.A., 2004. Speciation. Sunderland, MA: Sinauer Associates. + +Darwin, C., 1859. On the Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life. London: John Murray. + +Denef, V.J., Kalnejais, L.H., Mueller, R.S., et al., 2010. Proteogenomic basis for ecological divergence of closely related bacteria in natural acidophilic microbial communities. Proceedings of the National Academy of Sciences of the United States of America 107, 2383–2390. + +Doolittle, W.F., Zhaxybayeva, O., 2009. On the origin of prokaryotic species. Genome Research 19, 744–756. + +Dykhuizen, D.E., Brisson, D., Sandigursky, S., et al., 2008. The propensity of different Borrelia burgdorferi sensu stricto genotypes to cause disseminated infections in humans. The American Journal of Tropical Medicine and Hygiene 78, 806–810. + +Ellegaard, K.M., Klasson, L., Naslund, K., Bourtzis, K., Andersson, S.G., 2013. Comparative genomics of Wolbachia and the bacterial species concept. PLoS Genetics 9, e1003381. + +Francisco, J.C., Cohan, F.M., Krizanc, D., 2014. Accuracy and efficiency of algorithms for the demarcation of bacterial ecotypes from DNA sequence data. International Journal of Bioinformatics Research and Applications 10, 409–425. + +Gogarten, J.P., Townsend, J.P., 2005. Horizontal gene transfer, genome innovation and evolution. Nature Reviews. Microbiology 3, 679–687. + +Goris, J., Konstantinidis, K.T., Klappenbach, J.A., et al., 2007. DNA−DNA hybridization values and their relationship to whole-genome sequence similarities. International Journal of Systematic and Evolutionary Microbiology 57, 81–91. + +Guttman, D.S., Dykhuizen, D.E., 1994. Detecting selective sweeps in naturally occurring Escherichia coli. Genetics 138, 993–1003. + +Guttman, D.S., Mchardy, A.C., Schulze-Lefert, P., 2014. Microbial genome-enabled insights into plant-microorganism interactions. Nature Reviews. Genetics 15, 797–813. + +Haldane, J.B.S., 1932. The Causes of Evolution. London: Longmans, Green, and Co. + +Hey, J., 2001. Genes, Categories, and Species: The Evolutionary and Cognitive Cause of the Species Problem. Oxford: Oxford University Press. + +Ho, S.Y., Shapiro, B., 2011. Skyline-plot methods for estimating demographic history from nucleotide sequences. Molecular Ecology Resources 11, 423–434. + +Hunt, D.E., David, L.A., Gevers, D., et al., 2008. Resource partitioning and sympatric differentiation among closely related bacterioplankton. Science 320, 1081–1085. + +Hutchinson, G.E., 1968. When are species necessary? In: Lewontin, R.C. (Ed.), Population Biology and Evolution. Syracuse: Syracuse University Press. + +Jensen, E.C., Schrader, H.S., Rieland, B., et al., 1998. Prevalence of broadhost-range lytic bacteriophages of Sphaerotilus natans, Escherichia coli, and Pseudomonas aeruginosa. Applied and Environmental Microbiology 64, 575–580. + +Kashtan, N., Roggensack, S.E., Rodrigue, S., et al., 2014. Single-cell genomics reveals hundreds of coexisting subpopulations in wild. Prochlorococcus. Science 344, 416–420. + +Koeppel, A., Perry, E.B., Sikorski, J., et al., 2008. Identifying the fundamental units of bacterial diversity: A paradigm shift to incorporate ecology into bacterial systematics. Proceedings of the National Academy of Sciences 105, 2504–2509. + +Koeppel, A.F., Wertheim, J.O., Barone, L., et al., 2013. Speedy speciation in a bacterial microcosm: New species can arise as frequently as adaptations within a species. ISME Journal 7, 1080–1091. + +Konstantinidis, K.T., Tiedje, J.M., 2005. Towards a genome-based taxonomy for prokaryotes. Journal of Bacteriology 187, 6258–6264. + +Kopac, S., Cohan, F.M., 2011. A theory-based pragmatism for discovering and classifying newly divergent bacterial species. In: Tibayrenc, M. (Ed.), Genetics and Evolution of Infectious Diseases. London: Elsevier. + +Kopac, S., Wang, Z., Wiedenbeck, J., et al., 2014. Genomic heterogeneity and ecological speciation within one subspecies of Bacillus subtilis. Applied and Environmental Microbiology 80, 4842–4853. + +Kopac, S.M., Cohan, F.M., 2012. Comment on "Population genomics of early events in the ecological differentiation of bacteria". Science. 336. [Online]. + +Kumar, N., Lad, G., Giuntini, E., et al., 2015. Bacterial genospecies that are not ecologically coherent: Population genomics of Rhizobium leguminosarum. Open Biology 5, 140133. + +Majewski, J., Cohan, F.M., 1999a. Adapt globally, act locally: The effect of selective sweeps on bacterial sequence diversity. Genetics 152, 1459–1474. + +Majewski, J., Cohan, F.M., 1999b. DNA sequence similarity requirements for interspecific recombination in Bacillus. Genetics 153, 1525–1533. + +Mallet, J., 1995. A species definition for the modern synthesis. Trends in Ecology& Evolution 10, 294–299. + +Mallet, J., 2008. Hybridization, ecological races and the nature of species: empirical evidence for the ease of speciation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 363, 2971–2986. + +Malmstrom, R.R., Rodrigue, S., Huang, K.H., et al., 2013. Ecology of uncultured Prochlorococcus clades revealed through single-cell genomics and biogeographic analysis. ISME Journal 7, 184–198. + +Manning, S.D., Motiwala, A.S., Springman, A.C., et al., 2008. Variation in virulence among clades of Escherichia coli O157:H7 associated with disease outbreaks. Proceedings of the National Academy of Sciences of the United States of America 105, 4868–4873. + +Martiny, A.C., Tai, A.P., Veneziano, D., Primeau, F., Chisholm, S.W., 2009. Taxonomic resolution, ecotypes and the biogeography of Prochlorococcus. Environmental Microbiology 11, 823–832. + +Mayr, E., 1942. Systematics and the Origin of Species from the Viewpoint of a Zoologist. New York: Columbia University. + +Mayr, E., 1963. Animal Species and Evolution. Cambridge: Belknap Press of Harvard University Press. + +Mayr, E., 1982. The Growth of Biological Thought: Diversity, Evolution, and Inheritance. Cambridge: Harvard University Press. + +McDonald, D., Price, M.N., Goodrich, J., et al., 2012. An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea. ISME Journal 6, 610–618. + +Naor, A., Lapierre, P., Mevarech, M., Papke, R.T., Gophna, U., 2012. Low species barriers in halophilic Archaea and the formation of recombinant hybrids. Current Biology 22, 1444–1448. + +Papke, R.T., Zhaxybayeva, O., Feil, E.J., et al., 2007. Searching for species in haloarchaea. Proceedings of the National Academy of Sciences of the United States of America 104, 14092–14097. + +Polz, M.F., Hunt, D.E., Preheim, S.P., Weinreich, D.M., 2006. Patterns and mechanisms of genetic and phenotypic differentiation in marine microbes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 361, 2009–2021. + +Popa, O., Dagan, T., 2011. Trends and barriers to lateral gene transfer in prokaryotes. Current Opinion in Microbiology 14, 615–623. + +de Queiroz, K., 2005. Ernst Mayr and the modern concept of species. Proceedings of the National Academy of Sciences of the United States of America 102 (Suppl 1), 6600–6607. + +Rainey, P.B., Travisano, M., 1998. Adaptive radiation in a heterogeneous environment. Nature 394, 69–72. + +Retchless, A.C., Lawrence, J.G., 2010. Phylogenetic incongruence arising from fragmented speciation in enteric bacteria. Proceedings of the National Academy of Sciences of the United States of America 107, 11453–11458. + +Rosselló-Mora, R., Amann, R., 2001. The species concept for prokaryotes. FEMS Microbiology Reviews 25, 39–67. diff --git a/outputs/long_tiny_text/12_pg199_pg1_pg1_repeat1.md b/outputs/long_tiny_text/12_pg199_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b27833a2695e14a757d26813712ddf08173b7fa0 --- /dev/null +++ b/outputs/long_tiny_text/12_pg199_pg1_pg1_repeat1.md @@ -0,0 +1,99 @@ +Edwards, S.V., Shultz, A.J., Campbell-Staton, S.C., 2015. Next-generation sequencing and the expanding domain of phylogeography. Folia Zoologica 64 (3), 187–206. + +Ekblom, R., Galindo, J., 2011. Applications of next generation sequencing in molecular ecology of non-model organisms. Heredity 107 (1), 1–15. + +Elith, J., Leathwick, J.R., 2009. Species distribution models: Ecological explanation and prediction across space and time. Annual Review of Ecology, Evolution, and Systematics 40, 677–697. Available at: http://www.annualreviews.org/eprint/ HWR4cusJrXYCSPZ9sUDj/full (accessed 11.01.16). doi:10.1146/annurev. ecolsys.110308.120159. + +Eme, D., Malard, F., Konecny-Dupré, L., Lefébure, T., Douady, C.J., 2013. Bayesian phylogeographic inferences reveal contrasting colonization dynamics among European groundwater isopods. Molecular Ecology 22 (22), 5685–5699. + +Estoup, A., Baird, S.J.E., Ray, N., et al., 2010. Combining genetic, historical and geographical data to reconstruct the dynamics of bioinvasions: Application to the cane toad Bufo marinus. Molecular Ecology Resources 10 (5), 886–901. + +Excoffier, L., Dupanloup, I., Huerta-Sánchez, E., Sousa, V.C., Foll, M., 2013. Robust demographic inference from genomic and SNP data. PLOS Genetics 9 (10), e1003905. + +Felsenstein, J., 1975. A pain in the torus: Some difficulties with models of isolation by distance. The American Naturalist 109 (967), 359–368. + +Ford, E.B., Simpson, G.G., Jepsen, G.L., Mayr, E., 1949. Early Stages in Allopatric Speciation. Princeton, NJ: Princeton University Press. + +Gamble, T., Bauer, A.M., Greenbaum, E., Jackman, T.R., 2008. Evidence for Gondwanan vicariance in an ancient clade of gecko lizards. Journal of Biogeography 35 (1), 88–104. + +Gavin, D.G., Fitzpatrick, M.C., Gugger, P.F., et al., 2014. Climate refugia: Joint inference from fossil records, species distribution models and phylogeography. New Phytologist 204 (1), 37–54. + +Goldberg, E.E., Lancaster, L.T., Ree, R.H., 2011. Phylogenetic inference of reciprocal effects between geographic range evolution and diversification. Systematic Biology 60 (4), 451–465. + +Hey, J., 2005. On the number of New World founders: A population genetic portrait of the peopling of the Americas. PLOS Biology 3 (6), e193. + +Hey, J., Nielsen, R., 2004. Multilocus methods for estimating population sizes, migration rates and divergence time, with applications to the divergence of Drosophila pseudoobscura and D. persimilis. Genetics 167 (2), 747–760. + +Hickerson, M.J., Gilchrist, M.A., Takebayashi, N., 2003. Calibrating a molecular clock from phylogeographic data: Moments and likelihood estimators. Evolution; International Journal of Organic Evolution 57, 2216–2225. + +Hickerson, M.J., Meyer, C., 2008. Testing comparative phylogeographic models of marine vicariance and dispersal using a hierarchical Bayesian approach. BMC Evolutionary Biology 8, 322. + +Hickerson, M.J., Stahl, E.A., Lessios, H.A., 2006. Test for simultaneous divergence using approximate Bayesian computation. Evolution; International Journal of Organic Evolution 60 (12), 2435–2453. + +Ho, S.Y.W., Tong, K.J., Foster, C.S.P., et al., 2015. Biogeographic calibrations for the molecular clock. Biology Letters 11 (9), 20150194. + +Hooker, J.D., 1853. Introductory Essay to the Flora of New Zealand. London: Lovell Reeve. + +von Humboldt, A., Bonpland, A., 1807. Essai Sur La Géographie Des Plantes. Paris: Chez Levrault, Schoell et compagnie, libraires, XIII–1805. + +Hung, C.-M., Drovetski, S.V., Zink, R.M., 2013. Recent allopatric divergence and niche evolution in a widespread Palearctic bird, the common rosefinch (Carpodacus erythrinus). Molecular Phylogenetics and Evolution 66 (1), 103–111. + +Ilves, K.L., Huang, W., Wares, J.P., Hickerson, M.J., 2010. Colonization and/or mitochondrial selective sweeps across the North Atlantic intertidal assemblage revealed by multi-taxa approximate Bayesian computation. Molecular Ecology 19 (20), 4505–4519. + +Jordan, D.S., 1905. The origin of species through isolation. Science 22, 545–562. Jordan, D.S., 1908. The law of geminate species. The American Naturalist 42, 73–80. + +Joseph, L., Moritz, C., Hugall, A., 1995. Molecular support for vicariance as a source of diversity in rainforest. Proceedings of the Royal Society B: Biological Sciences 260 (1358), 177–182. + +Kelleher, J., Barton, N.H., Etheridge, A.M., 2013. Coalescent simulation in continuous space. Bioinformatics. Available at: http://bioinformatics. oxfordjournals.org/content/early/2013/02/07/bioinformatics.btt067.abstract (accessed 11.01.16). doi:10.1093/bioinformatics/btt067. + +Kelleher, J., Etheridge, A.M., Barton, N.H., 2014. Coalescent simulation in continuous space: Algorithms for large neighbourhood size. Theoretical Population Biology 95, 13–23. + +Knowlton, N., Weigt, L.A., 1998. New dates and new rates for divergence across the Isthmus of Panama. Proceedings of the Royal Society B: Biological Sciences 265, 2257–2263. + +Kühnert, D., Wu, C.-H., Drummond, A.J., 2011. Phylogenetic and epidemic modeling of rapidly evolving infectious diseases. Infection, Genetics and Evolution: Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases 11 (8), 1825–1841. + +Kuzmina, N.A., Lemey, P., Kuzmin, I.V., et al., 2013. The phylogeography and spatiotemporal spread of south-central skunk rabies virus. PLOS ONE 8 (12), e82348. + +Lacey Knowles, L., Alvarado-Serrano, D.F., 2010. Exploring the population genetic consequences of the colonization process with spatio-temporally explicit models: Insights from coupled ecological, demographic and genetic models in montane grasshoppers. Molecular Ecology 19 (17), 3727–3745. + +Lande, R., 1980. Genetic variation and phenotypic evolution during allopatric speciation. The American Naturalist 116 (4), 463–479. + +Landis, M.J., Matzke, N.J., Moore, B.R., Huelsenbeck, J.P., 2013. Bayesian analysis of biogeography when the number of areas is large. Systematic Biology 62 (6), 789–804. + +Lemey, P., Rambaut, A., Welch, J.J., Suchard, M.A., 2010. Phylogeography takes a relaxed random walk in continuous space and time. Molecular Biology and Evolution 27 (8), 1877–1885. + +Lessios, H.A., 1998. The first stage of speciation as seen in organisms separated by the Isthmus Panama. In: Howard, D.J., Berlocher, S. (Eds.), Endless Forms: Species and Speciation. Oxford: Oxford University Press, pp. 186–201. + +Lessios, H.A., 2008. The Great American Schism: Divergence of marine organisms after the rise of the Central American Isthmus. Annual Review of Ecology, Evolution, and Systematics 39, 63–91. + +Lessios, H.A., 2015. Appearance of an early closure of the Isthmus of Panama is the product of biased inclusion of data in the metaanalysis. Proceedings of the National Academy of Sciences of the United States of America 112 (43), E5765. + +Limic, V., Sturm, A., 2006. The spatial Λ-coalescent. Electronic Journal of Probability 11 (15), 363–393. + +Locke, D.P., Hillier, L.W., Warren, W.C., et al., 2011. Comparative and demographic analysis of orangutan genomes. Nature 469 (7331), 529–533. + +Losos, J.B., Glor, R.E., 2003. Phylogenetic comparative methods and the geography of speciation. Trends in Ecology & Evolution 18, 220–227. + +Manel, S., Schwartz, M.K., Luikart, G., Taberlet, P., 2003. Landscape genetics: Combining landscape ecology and population genetics. Trends in Ecology & Evolution 18, 189–197. + +Mann, D.H., Groves, P., Reanier, R.E., et al., 2015. Life and extinction of megafauna in the ice-age Arctic. Proceedings of the National Academy of Sciences of the United States of America 112 (46), 14301–14306. + +Mao, K., Milne, R.I., Zhang, L., et al., 2012. Distribution of living Cupressaceae reflects the breakup of Pangea. Proceedings of the National Academy of Sciences of the United States of America 109 (20), 7793–7798. + +Marko, P.B., Eytan, R.I., Knowlton, N., 2015. Do large molecular sequence divergences imply an early closure of the Isthmus of Panama? Proceedings of the National Academy of Sciences of the United States of America 112 (43), E5766. + +Matzke, N.J., 2014. Model selection in historical biogeography reveals that founder-event speciation is a crucial process in island clades. Systematic Biology 63 (6), 951–970. + +Mayden, R.L., 1988. Vicariance biogeography, parsimony, and evolution in North American freshwater fishes. Systematic Zoology 37 (4), 329–355. + +Mayr, E., 1954. Geographic speciation in tropical echinoids. Evolution; International Journal of Organic Evolution 8, 1–18. + +McCartney, M.A., Keller, G., Lessios, H.A., 2000. Dispersal barriers in tropical oceans and speciation in Atlantic and eastern Pacific sea urchins of the genus Echinometra. Molecular Ecology 9 (9), 1391–1400. + +McGlone, M.S., 2005. Goodbye Gondwana. Journal of Biogeography 32 (5), 739–740. + +Meseguer, A.S., Lobo, J.M., Ree, R., Beerling, D.J., Sanmartín, I., 2015. Integrating fossils, phylogenies, and niche models into biogeography to reveal ancient evolutionary history: The case of Hypericum (hypericaceae). Systematic Biology 64 (2), 215–232. + +Metcalf, J.L., Prost, S., Nogués-Bravo, D., et al., 2014. Integrating multiple lines of evidence into historical biogeography hypothesis testing: A Bison bison case study. Proceedings of the Royal Society B: Biological Sciences 281 (1777), 20132782. + +Morrone, J.J., Carpenter, J.M., 1994. In search of a method for cladistic biogeography: An empirical comparison of component analysis, Brooks diff --git a/outputs/long_tiny_text/12_pg275_pg1_pg1_repeat1.md b/outputs/long_tiny_text/12_pg275_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..cb7e7bb0555a98c70489da1843d0d3994668ab81 --- /dev/null +++ b/outputs/long_tiny_text/12_pg275_pg1_pg1_repeat1.md @@ -0,0 +1,127 @@ +Bergmann, C., 1847. Ueber die Verhaeltnisse der Waermeoekonomie der Thiere zu ihrer Groesse. Goettinger Studien 3, 595–708. + +Bess, E.C., Catanach, T.A., Johnson, K.P., 2013. The importance of molecular dating analyses for inferring Hawaiian biogeographical history: A case study with bark lice (Psocidae: Ptycta). Journal of Biogeography 41, 158–167. + +Blackburn, T.M., Hawkins, B.A., 2004. Bergmann’s rule and the mammal fauna of northern North America. Ecography 27, 715–724. + +Brooks, D.R., 1988. Scaling effects in historical biogeography: A new view of space, time, and form. Systematic Biology 37, 237–244. + +Brown, W.L., Wilson, E.O., 1956. Character displacement. Systematic Zoology 5, 49–64. Brown, J.H., 1995. Macroecology. Chicago, IL: University of Chicago Press. + +Bowen, L., Van Vuren, D., 1997. Insular endemic plants lack defenses against herbivores. Conservation Biology 11, 1249–1254. + +Brown, J.H., Gillooly, J.F., Allen, A.P., Savage, V.M., West, G.B., 2004. Toward a metabolic theory of ecology. Ecology 85, 1771–1789. + +Carlquist, S., 1967. The biota of long-distance dispersal. V. Plant dispersal to Pacific Islands. Bulletin of the Torrey Botanical Club 94, 129–162. + +Carlquist, S., 1974. Island Biology. New York, NY; London: Columbia University Press. + +Caujape-Castells, J., Tye, A., Crawford, D.J., et al., 2010. Conservation of oceanic island floras: Present and future global challenges. Perspectives in Plant Ecology, Evolution and Systematics 12, 107–129. + +Clusella-Trullas, S., van Wyk, J.H., Spotila, J.R., 2007. Thermal melanism in ectotherms. Journal of Thermal Biology 32, 235–245. + +Cody, M.L., Overton, J.M., 1996. Short-term evolution of reduced dispersal in island plant populations. Journal of Ecology 84, 53–61. + +Colwell, R.K., Rahbek, C., Gotelli, N.J., 2004. The mid-domain effect and species richness patterns: What have we learned so far? American Naturalist 163, 1–23. + +Cook, B.D., Pringle, C.M., Hughes, J.M., 2008. Molecular evidence for sequential colonization and taxon cycling in freshwater decapod shrimps on a Caribbean island. Molecular Ecology 17, 1066–1075. + +Cracraft, J., 1994. Species diversity, biogeography, and the evolution of biotas. American Zoologist 34, 33–47. + +Darwin, C., 1859. The Origin of Species. London: Reprinted by Penguin Books. + +De Micco, V., Aronne, G., 2012. Morpho-anatomical traits for plant adaptation to drought. In: Aroca, R. (Ed.), Plant Responses to Drought Stress. Berlin; Heidelberg: Springer, pp. 37–61. + +Duncan, R.P., Blackburn, T.M., 2004. Extinction and endemism in the New Zealand avifauna. Global Ecology and Biogeography 13, 509–517. + +Economo, E.P., Sarnat, E.M., 2012. Revisiting the ants of Melanesia and the taxon cycle: Historical and human-mediated invasions of a tropical archipelago. American Naturalist 180, 1–16. + +Evans, K.L., Newson, S.E., Storch, D., Greenwood, J.J., Gaston, K.J., 2008. Spatial scale, abundance and the species-energy relationship in British birds. Journal of Animal Ecology 77, 395–405. + +Fernández-Palacios, J.M., de Nascimento, L., Otto, R., et al., 2011. A reconstruction of Palaeo-Macaronesia, with particular reference to the long-term biogeography of the Atlantic island laurel forests. Journal of Biogeography 38, 226–246. + +Fine, P.V.A., 2015. Ecological and evolutionary drivers of geographic variation in species diversity. Annual Review of Ecology, Evolution, and Systematics. + +doi:10.1146/annurev-ecolsys-112414−054102. + +Fine, P.V.A., Ree, R.H., 2006. Evidence for a time-integrated species-area effect on the latitudinal gradient in tree diversity. American Naturalist 168, 796–804. + +Fleishman, E., Austin, G.T., Weiss, A.D., 1998. An empirical test of Rapoport's rule: Elevational gradients in montane butterfly communities. Ecology 79, 2482–2493. + +Flenley, J.R., 2011. Why is pollen yellow? and why are there so many species in the tropical rain forest? Journal of Biogeography 38, 809–816. + +Frederickson, M., Greene, M., Gordon, D., 2005. Devil's gardens' bedevilled by ants. Nature 437, 495–496. + +Fukami, T., 2015. Historical contingency in community assembly: Integrating niches, species pools, and priority effects. Annual Review of Ecology Evolution and Systematics 46. doi:10.1146/annurev-ecolsys-110411−160340. + +Funk, V.A., Wagner, W.L., 1995. Biogeographic patterns in the Hawaiian archipelago. In: Wagner, W.L., Funk, V.A. (Eds.), Hawaiian Biogeography: Evolution on a Hot Spot Archipelago. Washington, DC: Smithsonian Institution Press, pp. 379–419. + +Gaston, K.J., Blackburn, T.M., Spicer, J.I., 1998. Rapoport’s rule: Time for an epitaph? Trends in Ecology and Evolution 13, 70–74. + +Gaston, K.J., 2000. Global patterns in biodiversity. Nature 405, 220–227. + +Gell-Mann, M., 1994. Complex adaptive systems. In: Cowan, D., Pine, D., Meltzer, D. (Eds.), Complexity: Metaphors, Models, and Reality. Boston, MA: Addison- + +Wesley, pp. 17–45. SFI Studies in the Sciences of Complexity, Proc. Vol XIX. + +Ghalambor, C.K., Huey, R.B., Martin, P.R., Tewksbury, J.J., Wang, G., 2006. Are mountain passes higher in the tropics? Janzen’s hypothesis revisited. Integrative and Comparative Biology 46, 5–17. + +Gillespie, R.G., Baldwin, B.G., Waters, J.M., et al., 2012. Long-distance dispersal − a framework for hypothesis testing. Trends in Ecology & Evolution 27, 47–56. + +Gillespie, R.G., Roderick, G.K., 2014. Evolution: Geology and climate drive diversification. Nature 509, 297–298. + +Gillooly, J.F., Allen, A.P., Savage, V.-M., West, G.B., 2004. Towards a metabolic theory of ecology. Ecology 85, 1771–1789. + +Gohli, J., Leder, E.H., Garcia del Rey, E., et al., 2015. The evolutionary history of Afrocanarian blue tits inferred from genomewide SNPs. Molecular Ecology 24, 180–191. + +Guimarães Jr, P.R., Jordano, P., Thompson, J.N., 2011. Evolution and coevolution in mutualistic networks. Ecology Letters 14, 877–885. + +Gunderson, L.H., Holling, C.S., 2002. Panarchy: Understanding Transformations in Human and Natural Systems. Washington, DC: Island Press. + +Hamann, O., 2001. Demographic studies of three indigenous stand-forming plant taxa (Scalesia, Opuntia, and Bursera) in the Galápagos Islands, Ecuador. Biodiversity and Conservation 10, 223–250. + +Harmon, L.J., Harrison, S., 2015. Species diversity is dynamic and unbounded at local and continental. American Naturalist 185, 584–593. + +Harter, D.E., Irl, S.D., Seo, B., et al., 2015. Impacts of global climate change on the floras of oceanic islands − Projections, implications and current knowledge. Perspectives in Plant Ecology, Evolution and Systematics 17, 160–183. + +Heleno, R., Vargas, P., 2015. How do islands become green? Global Ecology and Biogeography 24, 518–526. + +Hermes, K., 1955. Lage der oberen Waldgrenze in den Gebirgen der Erde und ihr Abstand zur Schneegrenze. Kölner Geographische Abhandlungen 5, 255 pp. + +Hillebrand, H., 2004. On the generality of the latitudinal diversity gradient. American Naturalist 163, 192–211. + +Hoagstrom, C.W., Ung, V., Taylor, K., 2014. Miocene rivers and taxon cycles clarify the comparative biogeography of North American highland fishes. Journal of Biogeography 41, 644–658. + +Hoch, G., Körner, C., 2005. Growth, demography and carbon relations of Polylepis trees at the world's highest treeline. Functional Ecology 19, 941–951. + +Holtmeier, F.K., 2009. Mountain Timberlines: Ecology, Patchiness, and Dynamics. Berlin: Springer Science & Business Media. + +Irl, S.D.H., Anthelme, F., Harter, D.E., et al., 2015. Patterns of island treeline elevation − a global perspective. Ecography. doi:10.1111/ecog.01266. + +Irl, S.D.H., Steinbauer, M.J., Messinger, J., et al., 2014. Burned and devoured − Introduced herbivores, fire and the endemic flora of the high elevation ecosystem on La Palma, Canary Islands. Arctic Antarctic and Alpine Research 46, 859–869. + +Jacquemyn, H., Honnay, O., Pailler, T., 2007. Range size variation, nestedness and species turnover of orchid species along an altitudinal gradient on Réunion Island: Implications for conservation. Biological Conservation 136, 388–397. + +Janzen, D.H., 1967. Why mountain passes are higher in the tropics. American Naturalist 101, 233–249. + +Jønsson, K.A., Irestedt, M., Christidis, L., et al., 2014. Evidence of taxon cycles in an Indo-Pacific passerine bird radiation (Aves: Pachycephala). Proceedings of the Royal Society of London B: Biological Sciences 281, 20131727. + +Karger, D.N., Kluge, J., Krömer, T., et al., 2011. The effect of area on local and regional elevational patterns of species richness. Journal of Biogeography 38, 1177–1185. + +Kier, G., Kreft, H., Lee, T.M., et al., 2009. A global assessment of endemism and species richness across island and mainland regions. Proceedings of the National Academy of Sciences 106, 9322–9327. + +Kissling, W.D., Baker, W.J., Balslev, H., et al., 2012. Quaternary and pre-quaternary historical legacies in the global distribution of a major tropical plant lineage. Global Ecology and Biogeography 21, 909–921. + +Körner, C., 2012. Alpine Treelines: Functional Ecology of the Global High Elevation Tree Limits. Berlin: Springer Science & Business Media. + +Körner, C., Paulsen, J., 2004. A world-wide study of high altitude treeline temperatures. Journal of Biogeography 31, 713–732. + +Kraft, N.J., Comita, L.S., Chase, J.M., et al., 2011. Disentangling the drivers of beta diversity along latitudinal and elevational gradients. Science 333, 1755–1758. + +Kreft, H., Jetz, W., Mutke, J., Kier, G., Barthlott, W., 2008. Global diversity of island floras from a macroecological perspective. Ecology Letters 11, 116–127. + +Kueffer, C., Daehler, C.C., Torres-Santana, C.W., et al., 2010. A global comparison of plant invasions on oceanic islands. Perspectives in Plant Ecology, Evolution and Systematics 12, 145–161. + +Lavergne, S., Thompson, J.D., Garnier, E., Debussche, M., 2004. The biology and ecology of narrow endemic and widespread plants: A comparative study of trait variation in 20 congeneric pairs. Oikos 107, 505–518. + +Lens, F., Davin, N., Smets, E., del Arco, M., 2013. Insular woodiness on the Canary Islands: A remarkable case of convergent evolution. International Journal of Plant Sciences 174, 992–1013. diff --git a/outputs/long_tiny_text/12_pg71_pg1_pg1_repeat1.md b/outputs/long_tiny_text/12_pg71_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f694957e0ea66900c6f2dcd7e4f3eed696c09968 --- /dev/null +++ b/outputs/long_tiny_text/12_pg71_pg1_pg1_repeat1.md @@ -0,0 +1,111 @@ +Kelly, J.K., 1997. A test of neutrality based on interlocus associations. Genetics 146 (3), 1197–1206. + +Kim, S.Y., Pritchard, J.K., 2007. Adaptive evolution of conserved noncoding elements in mammals. PLoS Genetics 3 (9), e147. + +Kim, Y., Stephan, W., 2002. Detecting a local signature of genetic hitchhiking along a recombining chromosome. Genetics 160 (2), 765–777. + +Kim, Y., Stephan, W., 2003. Selective sweeps in the presence of interference among partially linked loci. Genetics 164 (1), 389–398. + +Kimura, M., 1985. The Neutral Theory of Molecular Evolution. Cambridge: Cambridge University Press. + +Knudsen, B., Miyamoto, M.M., 2001. A likelihood ratio test for evolutionary rate shifts and functional divergence among proteins. Proceedings of the National Academy of Sciences of the United States of America 98 (25), 14512–14517. + +Knudsen, B., Miyamoto, M.M., Laipis, P.J., Silverman, D.N., 2003. Using evolutionary rates to investigate protein functional divergence and conservation: A case study of the carbonic anhydrases. Genetics 164 (4), 1261–1269. + +Le, S.Q., Gascuel, O., 2008. An improved general amino acid replacement matrix. Molecular Biology and Evolution 25 (7), 1307–1320. + +Li, H., Stephan, W., 2006. Inferring the demographic history and rate of adaptive substitution in drosophila. PLoS Genetics 2 (10), e166. + +Li, W., Liu, B., Yu, L., et al., 2009. Phylogenetic analysis, structural evolution and functional divergence of the 12-oxo-phytodienoate acid reductase gene family in plants. BMC Evolutionary Biology 9 (1), 90. + +Lichtarge, O., Bourne, H.R., Cohen, F.E., 1996. An evolutionary trace method defines binding surfaces common to protein families. Journal of Molecular Biology 257 (2), 342–358. + +Lockless, S.W., Ranganathan, R., 1999. Evolutionarily conserved pathways of energetic connectivity in protein families. Science 286 (5438), 295–299. + +Margulies, E.H., Cooper, G.M., Asimenos, G., et al., 2007. Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Research 17 (6), 760–774. + +McDonald, J.H., Kreitman, M., 1991. Adaptive protein evolution at the adh locus in drosophila. Nature 351 (6328), 652–654. + +Mertz, B., Gu, X., Reilly, P.J., 2009. Analysis of functional divergence within two structurally related glycoside hydrolase families. Biopolymers 91 (6), 478495. + +Messier, W., Stewart, C.-B., 1997. Episodic adaptive evolution of primate lysozymes. Nature 385 (6612), 151–154. + +Miyata, T., Yasunaga, T., 1980. Molecular evolution of MRNa: A method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application. Journal of Molecular Evolution 16 (1), 23–36. + +Muse, S.V., Gaut, B.S., 1994. A likelihood approach for comparing synonymous and nonsynonymous nucleotide substitution rates, with application to the chloroplast genome. Molecular Biology and Evolution 11 (5), 715–724. + +Nei, M., Gojobori, T., 1986. Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Molecular Biology and Evolution 3 (5), 418–426. + +Nielsen, R., 2001. Statistical tests of selective neutrality in the age of genomics. Heredity 86 (6), 641–647. + +Nielsen, R., 2005. Molecular signatures of natural selection. Annual Review of Genetics 39, 197–218. + +Nielsen, R., Bustamante, C., Clark, A.G., et al., 2005. A scan for positively selected genes in the genomes of humans and chimpanzees. PLoS Biology 3 (6), e170. + +Nielsen, R., Hubisz, M.J., Hellmann, I., et al., 2009. Darwinian and demographic forces affecting human protein coding genes. Genome Research 19 (5), 838–849. + +Nielsen, R., Yang, Z., 1998. Likelihood models for detecting positively selected amino acid sites and applications to the hiv-1 envelope gene. Genetics 148 (3), 929–936. + +Parsch, J., Novozhilov, S., Saminadin-Peter, S.S., Wong, K.M., Andolfatto, P., 2010. On the utility of short intron sequences as a reference for the detection of positive and negative selection in drosophila. Molecular Biology and Evolution 27 (6), 1226–1234. + +Penn, O., Stern, A., Rubinstein, N.D., et al., 2008. Evolutionary modeling of rate shifts reveals specificity determinants in hiv-1 subtypes. PLoS Computational Biology 4 (11), e1000214. + +Pollard, K.S., Hubisz, M.J., Rosenbloom, K.R., Siepel, A., 2010. Detection of nonneutral substitution rates on mammalian phylogenies. Genome Research 20 (1), 110–121. + +Pollard, K.S., Salama, S.R., King, B., et al., 2006a. Forces shaping the fastest evolving regions in the human genome. PLoS Genetics 2 (10), e168. + +Pollard, K.S., Salama, S.R., Lambert, N., et al., 2006b. An RNA gene expressed during cortical development evolved rapidly in humans. Nature 443 (7108), 167–172. + +Pond, S.L.K., Frost, S.D., 2005. Not so different after all: A comparison of methods for detecting amino acid sites under selection. Molecular Biology and Evolution 22 (5), 1208–1222. + +Pool, J.E., Hellmann, I., Jensen, J.D., Nielsen, R., 2010. Population genetic inference from genomic sequence variation. Genome Research 20 (3), 291–300. + +Prabhakar, S., Noonan, J.P., Paabo, S., Rubin, E.M., 2006. Accelerated evolution of conserved noncoding sequences in humans. Science 314 (5800), 786. + +Pupko, T., Galtier, N., 2002. A covarion-based method for detecting molecular adaptation: Application to the evolution of primate mitochondrial genomes. Proceedings of the Royal Society of London B: Biological Sciences 269 (1498), 1313–1316. + +Ratnakumar, A., Mousset, S., Glemin, S., et al., 2010. Detecting positive selection within genomes: The problem of biased gene conversion. Philosophical Transactions of the Royal Society B: Biological Sciences 365 (1552), 2571–2580. + +Rockman, M.V., Hahn, M.W., Soranzo, N., et al., 2005. Ancient and recent positive selection transformed opioid cis-regulation in humans. PLoS Biology 3 (12), e387. + +Sabeti, P.C., Reich, D.E., Higgins, J.M., et al., 2002. Detecting recent positive selection in the human genome from haplotype structure. Nature 419 (6909), 832–837. + +Sawyer, S.A., Dykhuizen, D.E., Hartl, D.L., 1987. Confidence interval for the number of selectively neutral amino acid polymorphisms. Proceedings of the National Academy of Sciences of the United States of America 84 (17), 6225–6228. + +Sawyer, S.A., Hartl, D.L., 1992. Population genetics of polymorphism and divergence. Genetics 132 (4), 1161–1176. + +Siepel, A., Haussler, D., 2005. Phylogenetic hidden markov models. In: Nielsen, R. (Ed.), Statistical Methods in Molecular Evolution. New York: Springer, pp. 325–351. + +Suel, G.M., Lockless, S.W., Wall, M.A., Ranganathan, R., 2003. Evolu-tionarily conserved networks of residues mediate allosteric communication in proteins. Nature Structural & Molecular Biology 10 (1), 59–69. + +Susko, E., Inagaki, Y., Field, C., Holder, M.E., Roger, A.J., 2002. Testing for differences in rates-across-sites distributions in phylogenetic subtrees. Molecular Biology and Evolution 19 (9), 1514–1523. + +Swanson, W.J., Nielsen, R., Yang, Q., 2003. Pervasive adaptive evolution in mammalian fertilization proteins. Molecular Biology and Evolution 20 (1), 1820. + +Tajima, F., 1989. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123 (3), 585–595. + +Torgerson, D.G., Boyko, A.R., Hernandez, R.D., et al., 2009. Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence. PLoS Genetics 5 (8), e1000592. + +Wang, H.-C., Spencer, M., Susko, E., Roger, A.J., 2007. Testing for covarion-like evolution in protein sequences. Molecular Biology and Evolution 24 (1), 294–305. + +Weir, B.S., Cardon, L.R., Anderson, A.D., Nielsen, D.M., Hill, W.G., 2005. Measures of human population structure show heterogeneity among genomic regions. Genome Research 15 (11), 1468–1476. + +Whelan, S., Goldman, N., 2001. A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approach. Molecular Biology and Evolution 18 (5), 691–699. + +Williamson, S.H., Hernandez, R., Fledel-Alon, A., et al., 2005. Simultaneous inference of selection and population growth from patterns of variation in the human genome. Proceedings of the National Academy of Sciences of the United States of America 102 (22), 7882–7887. + +Wong, W.S., Nielsen, R., 2004. Detecting selection in noncoding regions of nucleotide sequences. Genetics 167 (2), 949–958. + +Wray, G.A., Hahn, M.W., Abouheif, E., et al., 2003. The evolution of transcriptional regulation in eukaryotes. Molecular Biology and Evolution 20 (9), 1377–1419. + +Yang, Z., 1998. Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution. Molecular Biology and Evolution 15 (5), 568–573. + +Yang, Z., Bielawski, J.P., 2000. Statistical methods for detecting molecular adaptation. Trends in Ecology & Evolution 15 (12), 496–503. + +Yang, Z., Nielsen, R., 2000. Estimating synonymous and nonsynonymous substitution rates under realistic evolutionary models. Molecular Biology and Evolution 17 (1), 32–43. + +Yang, Z., Nielsen, R., Goldman, N., 2009. In defense of statistical methods for detecting positive selection. Proceedings of the National Academy of Sciences of the United States of America 106 (36), E95. + +Yang, Z., Swanson, W.J., 2002. Codon-substitution models to detect adaptive evolution that account for heterogeneous selective pressures among site classes. Molecular Biology and Evolution 19 (1), 49–57. + +Zhai, W., Nielsen, R., Goldman, N., Yang, Z., 2012. Looking for Darwin in genomic sequences validity and success of statistical methods. Molecular Biology and Evolution 29 (10), 2889–2893. diff --git a/outputs/long_tiny_text/12_pg81_pg1_pg1_repeat1.md b/outputs/long_tiny_text/12_pg81_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8c3b9724c282915669d7bcf8b0224e465695ea89 --- /dev/null +++ b/outputs/long_tiny_text/12_pg81_pg1_pg1_repeat1.md @@ -0,0 +1,111 @@ +Cairns, J., Foster, P.L., 1991. Adaptive reversion of a frameshift mutation in Escherichia coli. Genetics 128, 695–701. + +Cairns, J., Overbaugh, J., Miller, S., 1988. The origin of mutants. Nature 335, 142–145. + +Cavalli-Sforza, L.L., Lederberg, J., 1956. Isolation of preadaptive mutants by sib-selection. Genetics 41, 367–381. + +Elde, N.C., Child, S.J., Eickbush, M.T., et al., 2012. Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses. Cell 150, 831–841. + +Elliott, K.T., Cuff, L.E., Neidle, E.L., 2013. Copy number change: Evolving views on gene amplification. Future Microbiology 8, 887–899. + +Foster, P.L., 1994. Population dynamics of a Lac- strain of Escherichia coli during selection for lactose utilization. Genetics 138, 253–261. + +Foster, P.L., 1999. Mechanisms of stationary phase mutation: A decade of adaptive mutation. Annual Review of Genetics 33, 57–88. + +Foster, P.L., 2000. Adaptive mutation in Escherichia coli. Cold Spring Harbor Symposia on Quantitative Biology 65, 21–29. + +Foster, P.L., 2004. Adaptive mutation in Escherichia coli. Journal of Bacteriology 186, 4846–4852. + +Foster, P.L., 2006. Methods for determining spontaneous mutation rates. Methods in Enzymology 409, 195–213. + +Foster, P.L., 2007. Stress-induced mutagenesis in bacteria. Critical Reviews in Biochemistry and Molecular Biology 42, 373–397. + +Foster, P.L., Cairns, J., 1992. Mechanisms of directed mutation. Genetics 131, 783–789. + +Foster, P.L., Rosche, W.A., 1999. Increased episomal replication accounts for the high rate of adaptive mutation in recD mutants of Escherichia coli. Genetics 152, 15–30. + +Foster, P.L., Trimarchi, J.M., 1994. Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runs. Science 265, 407–409. + +Foster, P.L., Trimarchi, J.M., 1995. Adaptive reversion of an episomal frameshift mutation in Escherichia coli requires conjugal functions but not actual conjugation. Proceedings of the National Academy of Sciences of the United States of America 92, 5487–5490. + +Fuchs, R.P., Fujii, S., 2013. Translesion DNA synthesis and mutagenesis in prokaryotes. Cold Spring Harbor Perspectives in Biology 5, a012682. + +Galhardo, R.S., Hastings, P.J., Rosenberg, S.M., 2007. Mutation as a stress response and the regulation of evolvability. Critical Reviews in Biochemistry and Molecular Biology 42, 399–435. + +Galitski, T., Roth, J.R., 1995. Evidence that F plasmid transfer replication underlies apparent adaptive mutation. Science 268, 421–423. + +Gawel, D., Pham, P.T., Fijalkowska, I.J., Jonczyk, P., Schaaper, R.M., 2008. Role of accessory DNA polymerases in DNA replication in Escherichia coli: Analysis of the dnaX36 mutator mutant. Journal of Bacteriology 190, 1730–1742. + +Gizatullin, F.S., Babynin, E.V., 1996. The selection-induced His + reversion in Salmonella typhimurium. Mutation Research 357, 43–56. + +Godoy, V.G., Fox, M.S., 2000. Transposon stability and a role for conjugational transfer in adaptive mutability. Proceedings of the National Academy of Sciences of the United States of America 97, 7393–7398. + +Hall, B.G., 1988. Adaptive evolution that requires multiple spontaneous mutations. I. Mutations involving an insertion sequence. Genetics 120, 887–897. + +Hall, B.G., 1990. Spontaneous point mutations that occur more often when advantageous than when neutral. Genetics 126, 5–16. + +Hall, B.G., 1991. Adaptive evolution that requires multiple spontaneous mutations: Mutations involving base substitutions. Proceedings of the National Academy of Sciences of the United States of America 88, 5882–5886. + +Harris, R.S., Longerich, S., Rosenberg, S.M., 1994. Recombination in adaptive mutation. Science 264, 258–260. + +Hastings, P.J., Slack, A., Petrosino, J.F., Rosenberg, S.M., 2004. Adaptive amplification and point mutation are independent mechanisms: Evidence for various stress-inducible mutation mechanisms. PLoS Biology 2, e399. + +Hendrickson, H., Slechta, E.S., Bergthorsson, U., Andersson, D.I., Roth, J.R., 2002. Amplification-mutagenesis: Evidence that "directed" adaptive mutation and general hypermutability result from growth with a selected gene amplification. Proceedings of the National Academy of Sciences of the United States of America 99, 2164–2169. + +Jin, J., Gao, P., Mao, Y., 2002. Occurrence of leu + revertants under starvation cultures in Escherichia coli is growth-dependent. BMC Genetics 3, 6. + +Kim, S.R., Matsui, K., Yamada, M., Gruz, P., Nohmi, T., 2001. Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli. Molecular Genetics and Genomics 266, 207–215. + +Kofoid, E., Bergthorsson, U., Slechta, E.S., Roth, J.R., 2003. Formation of an F' plasmid by recombination between imperfectly repeated chromosomal Rep sequences: A closer look at an old friend (F'(128) pro lac). Journal of Bacteriology 185, 660–663. + +Kondrashov, F.A., 2012. Gene duplication as a mechanism of genomic adaptation to a changing environment. Proceedings of the Royal Society B: Biological Sciences 279, 5048–5057. + +Kuban, W., Jonczyk, P., Gawel, D., et al., 2004. Role of Escherichia coli DNA polymerase IV in in vivo replication fidelity. Journal of Bacteriology 186, 4802–4807. + +Kugelberg, E., Kofoid, E., Reams, A.B., Andersson, D.I., Roth, J.R., 2006. Multiple pathways of selected gene amplification during adaptive mutation. Proceedings of the National Academy of Sciences of the United States of America 103, 17319–17324. + +Layton, J.C., Foster, P.L., 2003. Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli. Molecular Microbiology 50, 549–561. + +Lederberg, J., Lederberg, E.M., 1952. Replica plating and indirect selection of bacterial mutants. Jounal of Bacteriology 63, 399–406. + +Lombardo, M.J., Aponyi, I., Rosenberg, S.M., 2004. General stress response regulator RpoS in adaptive mutation and amplification in Escherichia coli. Genetics 166, 669–680. + +Luria, S.E., Delbrück, M., 1943. Mutations of bacteria from virus sensitivity to virus resistance. Genetics 28, 491–511. + +Maenhaut-Michel, G., Shapiro, J.A., 1994. The roles of starvation and selective substrates in the emergence of araB-lacZ fusion clones. EMBO Journal 13, 5229–5239. + +McKenzie, G., Lee, P., Lombardo, M.-J., Hastings, P., Rosenberg, S., 2001. SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification. Molecular Cell 7, 571–579. + +Miller, J.H., 1992. A Short Course in Bacterial Genetics. New York, NY: Cold Spring Harbor Laboratory Press. + +Mittler, J.E., Lenski, R.E., 1990. New data on excisions of Mu from E. coli MCS2 cast doubt on directed mutation hypothesis. Nature 344, 173–175. + +Mittler, J.E., Lenski, R.E., 1992. Experimental evidence for an alternative to directed mutation in the bgl operon. Nature 356, 446–448. + +Näsvall, J., Sun, L., Roth, J.R., Andersson, D.I., 2012. Real-time evolution of new genes by innovation, amplification, and divergence. Science 338, 384–387. + +Newcombe, H.B., 1949. Origin of bacterial variants. Nature 164, 150. + +Nilsson, A.I., Zorzet, A., Kanth, A., et al., 2006. Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes. Proceedings of the National Academy of Sciences of the United States of America 103, 6976–6981. + +Novick, A., Szilard, L., 1950. Experiments with the chemostat on spontaneous mutations of bacteria. Proceedings of the National Academy of Sciences of the United States of America 36, 708–719. + +Paulander, W., Andersson, D.I., Maisnier-Patin, S., 2010. Amplification of the gene for isoleucyl-tRNA synthetase facilitates adaptation to the fitness cost of mupirocin resistance in Salmonella enterica. Genetics 185, 305–312. + +Peters, J.E., Bartoszyk, I.M., Dheer, S., Benson, S.A., 1996. Redundant homosexual F transfer facilitates selection-induced reversion of plasmid mutations. Journal of Bacteriology 178, 3037–3043. + +Powell, S.C., Wartell, R.M., 2001. Different characteristics distinguish early versus late arising adaptive mutations in Escherichia coli FC40. Mutation Research 473, 219–228. + +Pranting, M., Andersson, D.I., 2011. Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation. Molecular Microbiology 79, 305–315. + +Prival, M.J., Cebula, T.A., 1992. Sequence analysis of mutations arising during prolonged starvation of Salmonella typhimurium. Genetics 132, 303–310. + +Prival, M.J., Cebula, T.A., 1996. Adaptive mutation and slow-growing revertants of an Escherichia coli lacZ amber mutant. Genetics 144, 1337–1341. + +Pybus, C., Pedraza-Reyes, M., Ross, C.A., et al., 2010. Transcription-associated mutation in Bacillus subtilis cells under stress. Journal of Bacteriology 192, 3321–3328. + +Quinones-Soto, S., Roth, J.R., 2011. Effect of growth under selection on appearance of chromosomal mutations in Salmonella enterica. Genetics 189, 37–53. + +Radicella, J.P., Park, P.U., Fox, M.S., 1995. Adaptive mutation in Escherichia coli: A role for conjugation. Science 268, 418–420. + +Reams, A.B., Kofoid, E., Savageau, M., Roth, J.R., 2010. Duplication frequency in a population of Salmonella enterica rapidly approaches steady state with or without recombination. Genetics 184, 1077–1094. diff --git a/outputs/long_tiny_text/13_pg162_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg162_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..de95bc695057e0491125cf69108113ac89f82c2b --- /dev/null +++ b/outputs/long_tiny_text/13_pg162_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +two different confessions under one common government, and, resulting from it, the possibility of changing from one confession to another, have all combined to free the state churches from any rigid interpretation of their theological formulas. A liberal and a conservative theology (rationalist and orthodox) exist side by side within the churches, and while the latter clings to the theology of the 16th century, the former ventures to raise doubts about the truth of such a common and simple standard as the Apostles' Creed. The extreme divergence in doctrinal position is fostered by the fact that the theology taught in the universities is in a great measure divorced from the practical religious life of the people, and the theological opinions uttered in the theological literature of the country cannot be held to express the thoughts of the members of the churches. In each state the sovereign is still held to be the summus episcopus . He appoints a minister of public worship, and through him nominates the members of the governing body, the Oberkirchenrath or Consistorium or Directorium . This council deals with the property, patronage and all other ecclesiastical matters. But each parish elects its own council for parochial affairs, which has a legal status and deals with such matters as the ecclesiastical assessments. Delegates from these parish councils form the Landessynode . In cases that call for consultation together, the Consistorium and the Synod appoint committees to confer. In Alsace-Lorraine about half of those entitled to vote appear at the polls; but in other districts of Germany very little interest is shown in the elections to the parish councils. + +The income of the state churches is derived from four sources. The state makes an annual provision for the stipends of the clergy, for the maintenance of fabrics and for other ecclesiastical needs. The endowments for church purposes, of which there are many, and which are destined to the support of foreign missions, clerical pensions, supply of books to the clergy, &c. are administered by the supreme council. The voluntary contributions of the people are all absorbed in the common income of the national churches and are administered by the supreme council. Each parish is legally entitled to levy ecclesiastical assessments for defined purposes. + +Appointments to benefices are in the hands of the state (sometimes with consent of parishes), of private patrons and of local parish councils. The number of these benefices is always increasing; and in 1897 they amounted to 16,400, or 300 more than in 1890. The state appoints to 56%, private and municipal patrons to 34%, and congregations to 10% of the whole. Customs vary in different states; thus in Schleswig-Holstein the state nominates but the parish elects; in Alsace-Lorraine the directorium or supreme consistory appoints, but the appointment must be confirmed by the viceroy; in Baden the state offers the parish a selection from six names and then appoints the one chosen. + +The Lutheran state churches of Denmark, Sweden and Norway have retained the episcopate. In all of them the king is recognized to be the summus episcopus or supreme authority in all ecclesiastical matters, but in Norway and Sweden his power is somewhat limited by that of parliament. The king exercises his ecclesiastical authority through a minister who superintends religion and education. The position and functions of the bishops vary in the different countries. In all the rite of ordination is in their hands. In Denmark they are the inspectors of the clergy and of the schools. In Sweden they preside over local consistories composed of clerical and lay members. The episcopate in all three countries accommodates itself to something like the Lutheran consistorial system of ecclesiastical government. + +The two leading religions within Germany are the Evangelical (Lutheran) and the Roman Catholic, including respectively 58 and 39% of the population. The proportions are continually varying, owing to the new migratory habits of almost every class of the population. Generally speaking, the Roman Catholics are on the increase in Prussia, Bavaria, Saxony and Württemberg; and the Evangelicals in the other districts of Germany, especially in the large cities. There is a growing tendency to + +mixed marriages, which are an important factor in religious changes. + +BIBLIOGRAPHY. —Richter, Die evangelischen Kirchenordnungen des sechzehnten Jahrhunderts (Weimar, 1846); Schling, Die evangelischen Kirchenordnungen des 16ten Jahrhunderts (Leipzig, 1902, &c.); Richter, Lehrbuch des katholischen und evangelischen Kirchenrechts (8th ed., Leipzig, 1886); Hundeshagen, Beiträge zur Kirchenverfassungsgeschichte und Kirchenpolitik insbesondere des Protestantismus, i. (Wiesbaden, 1864), or in Ausgewählte kl. Schriften, ii. (Gotha, 1875); Höfling, Grundsätze der evangelischen-Lutherischen Kirchenverfassung (Erlangen, 1850, 3rd ed., 1853); Drews, Das kirchl. Leben d. deutschen evangelischen Landeskirchen (Tübingen, 1902); Erich Förster, Die Enstehung der preussischen Landeskirchen unter der Regierung König Friedrich Wilhelms III., i. (Tübingen, 1905); Emil Schling, Geschichte der protestantischen Kirchenverfassung (Leipzig, 1907); articles in Herzog's Realencyklopädie für protest. Theologie (3rd ed.), on Kirchenregiment, Kirchenrecht, Kirchenordnung, Konsistorien, Episcopalsystem, Gemeinde, Kollegialsystem, Territorialsystem; Schaff, History of the Creeds of Christendom (London 1877). (T. M. L.) + +LUTHER LEAGUE, a religious association for young people in the United States of America. It began with a local society founded by delegates of six Lutheran church societies in New York City in 1888. The first national convention was held at Pittsburg, Pennsylvania, on the 30th and 31st of October 1895. The basis of the league is the Augsburg Confession. Its membership is open to "any society of whatever name connected with a Lutheran congregation or a Lutheran institution of learning." According to the constitution its objects are "to encourage the formation of the young people's societies in all Lutheran congregations in America, to urge their affiliation with their respective state or territorial leagues, and with this league to stimulate the various young people's societies to greater Christian activity and to foster the spirit of loyalty to the church." The league publishes a monthly paper, The Luther League Review , in Washington. According to its official report it had 70,000 members in 1906, which had increased to more than 100,000 in 1910. + +LUTON, a market town and municipal borough in the southern or Luton parliamentary division of Bedfordshire, England, 30 m. N.W. by N. of London by the Midland railway, served also by a branch of the Great Northern. Pop. (1901) 36,404. It lies in a narrow valley on the south flank of the Chiltern Hills, on the upper part of the river Lea. The church of St Mary is mainly Decorated, but has portions of Early English and Perpendicular work. It has brasses and monuments of interest and a late Decorated baptistery of stone, an ornate roofed structure, octagonal in form. The font within it is Early English. Luton is the principal seat in England of the straw-plait manufacture, and large quantities of hats and other straw goods have been exported, though in recent years the industry has suffered from increased foreign competition. The industry originated with the colony of straw-plaiters transplanted by James I. from Scotland, whither they had been brought from Lorraine by Queen Mary. The town has also foundries, motor car works and other manufactures. The borough is under a mayor, 6 aldermen and 18 councillors. Area, 3133 acres. + +LUTSK (Polish, Luck), a town of southern Russia, in the government of Volhynia, on the Styr, 51 m. by rail N.W. of Kovel. Pop. (1900) 17,701. It is supposed to have been founded in the 7th century; in the 11th century it was known as Luchesk, and was the chief town of an independent principality. In the 15th century it was the seat of a bishop and became wealthy, but during the wars between Russia and Poland in the second half of the 16th century, and especially after the extermination of its 40,000 inhabitants, it lost its importance. In 1791 it was taken by Russia. Its inhabitants, many of them Jews, live mainly-by shipping goods on the Styr. Among its buildings is a 16th-century castle. Lutsk is the seat of a Roman Catholic bishop. + +LUTTERWORTH, a market town in the Harborough parliamentary division of Leicestershire, England; 90 m. N.N.W. from London by the Great Central railway. Pop. (1901) 1734. It lies in a pleasant undulating country on the small river Swift, an affluent of the Avon. The church of St Mary is a fine building, + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg165_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg165_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7a1fe0972b9d8b602b55a80bec364ecbc2355956 --- /dev/null +++ b/outputs/long_tiny_text/13_pg165_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +of England at Leuze on September 18, 1691. Again in the next campaign he covered the king's siege of Namur, and defeated William at Steenkirk (q.v.) on June 5, 1692; and on July 29, 1693, he won his greatest victory over his old adversary at Neerwinden, after which he was called le tapissier de Nôtre Dame from the number of captured colours that he sent to the cathedral. He was received with enthusiasm at Paris by all but the king, who looked coldly on a relative and adherent of the Condés. St Simon describes in the first volume of his Memoirs how, instead of ranking as eighteenth peer of France according to his patent of 1661, he claimed through his wife to be duc de Piney of an old creation of 1571, which would place him second on the roll. The affair is described with St Simon's usual interest in the peerage, and was chiefly checked through his assiduity. In the campaign of 1694, Luxembourg did little in Flanders, except that he conducted a famous march from Vignamont to Tournay in face of the enemy. On his return to Versailles for the winter he fell ill, and died on January 4, 1695. In his last moments he was attended by the famous Jesuit priest Bourdaloue, who said on his death, "I have not lived his life, but I would wish to die his death." Luxembourg's morals were bad even in those times, and he had shown little sign of religious conviction. But as a general he was Condé's grandest pupil. Though slothful like Condé in the management of a campaign, at the moment of battle he seemed seized with happy inspirations, against which no ardour of William's and no steadiness of Dutch or English soldiers could stand. His death and Catinat's disgrace close the second period of the military history of the reign of Louis XIV., and Catinat and Luxembourg, though inferior to Condé and Turenne, were far superior to Tallard and Villeroi. He was distinguished for a pungent wit. One of his retorts referred to his deformity. "I never can beat that cursed humpback," William was reputed to have said of him. "How does he know I have a hump?" retorted Luxembourg, "he has never seen my back." He left four sons, the youngest of whom was a marshal of France as Maréchal de Montmorency. + +See, besides the various memoirs and histories of the time, Beaumain's Histoire militaire du duc de Luxembourg (Hague and Paris, 1756); Mémoires pour servir à l'histoire du maréchal duc de Luxembourg (Hague and Paris, 1758); Courcelles, Dictionnaire des généraux français (Paris, 1823), vol. viii. There are some interesting facts in Desormeaux's Histoire de la maison de Montmorency (1764), vols. iv. and v. Camille Rousset's Louvois and the recent biography of Luxembourg by Count de Ségur (1907) should also be studied. + +LUXEMBURG, a district in the European low countries, of which the eastern part forms the grand-duchy of Luxembourg, and the western is the Belgian province of that name (for map, see BELGIUM). The name is derived from the chief town. + +Under the Romans the district was included in the province of Belgica prima, afterwards forming part of the Frankish kingdom of Austrasia and of the empire of Charlemagne. About 1060 it came under the rule of Conrad (d. 1086), who took the title of count of Luxembourg. His descendants ruled the county, first in the male and then in the female line, until the death of the emperor Sigismund in 1437. Through the marriage of Sigismund's daughter, Elizabeth, with the German king, Albert II., Luxembourg, which had been made a duchy in 1354, passed to the house of Habsburg, but was seized in 1443 by Philip III. the Good, duke of Burgundy, who based his claim upon a bargain concluded with Sigismund's niece Elizabeth (d. 1451). Regained by the Habsburgs in 1477 when Mary, daughter and heiress of duke Charles the Bold, married the German king Maximilian I., the duchy passed to Philip II. of Spain in 1555, though subject to the laws of the empire, of which it still formed part. After a section had been ceded to France in 1659, the remainder was given to the emperor Charles VI. by the treaty of Utrecht in 1713. It was conquered by France in 1795, and retained by that power until the end of the Napoleonic wars. The congress of Vienna (1814-1815) erected Luxembourg into a grand-duchy, added part of the duchy of Bouillon to it, and assigned it to William I., king of the Netherlands, in return for the German territories of the house of Orange-Nassau, which Napoleon had + +confiscated in 1806, and which were given by the congress to the king of Prussia. In 1830 when the Belgian provinces separated from Holland, an effort was made to include Luxembourg in the new kingdom of the Belgians; but in November 1831 the powers decided that part of the grand-duchy should be retained by the king of Holland, who refused to accept this arrangement. Consequently the whole of Luxembourg remained in the possession of the Belgians until 1838, when the treaty of the 19th of April, concluded at the conference of London, enforced the partition of 1831. + +The grand-duchy of Luxembourg, the portion under the rule of William I. retaining the name, was ruled by the kings of Holland until the death of William III. in 1890. William's daughter, Wilhelmina, succeeded to the throne of Holland, but under the Salic law\(^1\) the grand-duchy passed to his kinsman; Adolphus, duke of Nassau, who died in 1905, and was succeeded by his son William (b. 1852). + +By modifications of the treaty of Vienna the garrisoning of the fortress of Luxembourg had passed into Prussian hands, an arrangement which lasted until 1867. In the previous year the German Confederation, to which the grand-duchy of Luxembourg had belonged since 1815, had been dissolved; but the Prussians maintained their garrison in Luxembourg, which was not included in the new North German Confederation, while King William III. proposed to sell his rights over the grand-duchy to France. The Prussians were irritated by this proposal, but war was averted, and the question was referred to a conference of the powers in London. The treaty of London, signed on the 1\(^{st}\) of May 1867, decided that the Prussian garrison must be withdrawn and the fortress dismantled, which was done in 1872. At the same time the great powers guaranteed the neutrality of the grand-duchy, and although a member of the German Zollverein, Luxembourg now forms a sovereign and independent state. + +The GRAND-DUCHY lies S.E. of Belgium. Its area is 999 sq. m., with a population (1905) of 246,455. The people are nearly all Catholics. The country is rich in iron ore. The hills in the south of the duchy are a continuation of the Lorraine plateau, and the northern districts are crossed in all directions by outrunners from the Ardennes. The streams mostly join the Moselle, which forms the boundary between Luxembourg and the Rhine province for about 20 m. The Sure or Sauer, the most important stream in the duchy, rises at Vaux-les-Rosières in Belgian Luxembourg, crosses the duchy, and forms the eastern boundary from the confluence of the Our till it joins the Moselle after a course of 50 m., during which it receives the Wiltz, Attert, Alzette, White and Black Ernz, &c. The soil of Luxembourg is generally good; the southern districts are on the whole the most fertile as well as the most populous. Building materials of all sorts are obtained throughout the duchy. Besides the iron furnaces, situated in the south near the Lorraine plateau, there are tanneries, weaving and glove-making factories, paper-mills for all sorts of paper, breweries and distilleries, and sugar refineries. A German patois mixed with French words is spoken throughout the country; but French, which is employed by the commercial community, is also the common speech on the French and Belgian frontiers. Though liberty of worship prevails, Roman Catholicism is almost the sole form. The government is in the hands of the grand-duke, who sanctions and promulgates the laws. There is a council (staatsrat) of 15 members. There is a chamber of deputies with 48 members elected by the cantons (12 in number) for six years, half the body being elected every three years. No law can be passed without the consent of the chamber. Bills are introduced by the grand-duke, but the house has also the right of initiative. A single battalion (150) of volunteers composes the grand-ducal army. The gendarmerie consists of about 150 men. There are cantonal courts and two + +\(^1\) It should be noticed, however, that the Salic law is subordinate to the Nassau family law, which provides for the succession in the case of the complete extinction of males. Thus Article xlii. of the Nassau Pact of the 30th of June 1783 provides "that in the event of the extinction of males, the rights of succession pass to the daughter or nearest heiress of the last male." + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg32_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg32_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..25e7a06e9f3c48b848e133801955add67a626e8a --- /dev/null +++ b/outputs/long_tiny_text/13_pg32_pg1_pg1_repeat1.md @@ -0,0 +1,31 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +the administration Lorraine preserved a grateful memory of the good king Stanislaus, who held his brilliant little court at Lunéville, and founded an academy and several libraries and hospitals. At his death in February 1766 the two duchies of Lorraine and Bar became definitively incorporated in the kingdom of France. The treaties of 1735 and 1736, however, guaranteed their legislation, the privileges enjoyed by the three orders, and their common law and customs tariffs, which they retained until the French Revolution. Lorraine and Barrois formed a large government corresponding, together with the little government of the three bishoprics, to the intendance of Lorraine and the généralité of Metz. For legal purposes, Metz had been the seat of a parlement since 1633, and the parlement of Nancy was created in 1776. There was, too, a chambre des comptes at Metz, and another at Bar-le-duc. (For the later history see ALSACE-LORRAINE.) + +See Dom. A. Calmet, Histoire ecclésiastique et civile de Lorraine (2nd ed., Nancy, 1747–1757); A. Digot, Histoire de Lorraine (1879–1880); E. Huhn, Geschichte Lothringens (Berlin, 1877); R. Parisot, Le Royaume de Lorraine sous les Carolingiens (Paris, 1899), Comte D'Haussonville, Histoire de la réunion de la Lorraine à la France (2nd ed., Paris, 1860); E. Bonvalot, Histoire du droit et des institutions de la Lorraine et des Trois-Évêchés (Paris, 1895), and E. Duvernoy, Les États Généraux des duchés de Lorraine et de Bar jusqu'à la majorité de Charles III. (Paris, 1904). (R. Po.) + +LORTZING, GUSTAV ALBERT (1801–1851), German composer, was born at Berlin on the 23rd of October 1801. Both his parents were actors, and when he was nineteen the son began to play youthful lover at the theatres of Düsseldorf and Aachen, sometimes also singing in small tenor or baritone parts. His first opera Ali Pascha von Jannina appeared in 1874, but his fame as a musician rests chiefly upon the two operas Der Wildschütz (1842) and Czar und Zimmermann (1837). The latter, although now regarded as one of the masterpieces of German comic opera, was received with little enthusiasm by the public of Leipzig. Subsequent performance in Berlin, however, provoked such a tempest of applause that the opera was soon placed on all the stages of Germany. It was translated into English, French, Swedish, Danish, Dutch, Bohemian, Hungarian and Russian. Der Wildschütz was based on a comedy of Kotzebue, and was a satire on the unintelligent and exaggerated admiration for the highest beauty in art expressed by the bourgeois gentilhomme . Of his other operas it is only necessary to note Der Pole und sein Kind , produced shortly after the Polish insurrection of 1831, and Undine (1845). Lortzing died at Berlin on the 21st of January 1851. + +LORY, CHARLES (1823–1889), French geologist, was born at Nantes on the 30th of July 1823. He graduated D. ès Sc. in 1847; in 1852 he was appointed to the chair of geology at the University of Grenoble, and in 1881 to that of the École Normale Supérieure in Paris. He was distinguished for his researches on the geology of the French Alps, being engaged on the geological survey of the departments of Isère, Drôme and the Hautes Alpes, of which he prepared the maps and explanatory memoirs. He dealt with some of the disturbances in the Savoy Alps, describing the fan-like structures, and confirming the views of J. A. Favre with regard to the overthrows, reversals and duplication of the strata. His contributions to geological literature include also descriptions of the fossils and stratigraphical divisions of the Lower Cretaceous and Jurassic rocks of the Jura. He died at Grenoble on the 3rd of May 1889. + +LORY (a word of Malayan origin signifying parrot, in general use with but slight variation of form in many European languages), the name of certain birds of the order Psittaci , mostly from the Moluccas and New Guinea, remarkable for their bright scarlet or crimson colouring, though also, and perhaps subsequently, applied to some others in which the plumage is chiefly green. The lories have been referred to a considerable number of genera, of which Lorius (the Domicilla of some authors), Eos and Chalcopsittacus may be here particularized, while under the name of "lorikeets" may be comprehended such genera as Trichoglossus , Charmosyna , Loriculus and Coriphilus . By most systematists some of these forms have been placed far apart, even in different families of Psittaci , but A. H. Garrod has + +shown (Proc. Zool. Society, 1874, pp. 586–598, and 1876, p. 692) the many common characters they possess, which thus goes some way to justify the relationship implied by their popular designation. A full account of these birds is given in the first part of Count T. Salvadori's Ornitologia della Papuasia e delle Molucche (Turin 1880), whilst a later classification appeared in Salvadori's section of the British Museum Catalogue of Birds, xx., 1891. + +Though the name lory has often been used for the species of Eclectus , and some other genera related thereto, modern writers would restrict its application to the birds of the genera Lorius , Eos , Chalcopsittacus and their near allies, which are often placed in a subfamily, Loriinae , belonging to the so-called family of Trichoglossidae or "brush-tongued" parrots. Garrod in his investigations on the anatomy of Psittaci was led not to attach much importance to the structure indicated by the epithet "brush-tongued" stating (Proc. Zool. Society, 1874, p. 597) that it "is only an excessive development of the papillae which are always found on the lingual surface." The birds of this group are very characteristic of the New Guinea subregion, 1 in which occur, according to Count Salvadori, ten species of Lorius, eight of Eos and four of Chalcopsittacus; but none seem here to require any further notice, 2 though among them, and particularly in the genus Eos , are included some of the most richly-coloured birds in the whole world; nor does it appear that more need be said of the lorikeets. + +The family is the subject of an excellent monograph by St George Mivart (London, 1896). (A. N.) + +LOS ANDES, a former state of Venezuela under the redivision of 1881, which covered the extreme western part of the republic N. of Zamora and S. of Zulia. In the redivision of 1904 Los Andes was cut up into three states—Mérida Táchira and Trujillo. + +LOS ANGELES, a city and the county-seat of Los Angeles county, in southern California, U.S.A., along the small Los Angeles river, in the foothills of the San Gabriel Mountains; a narrow strip, 18 m. long, joins the main part of the city to its water front on the ocean, San Pedro Bay. Pop. (1880) 11,183, (1890) 50,395, (1900) 102,479, of whom 19,964 were foreign-born; 3 the growth in population since 1900 has been very rapid and in 1910 it was 319,198. The city had in 1910 an area of 85.1 sq. m., of which more than one-half has been added since 1890. Los Angeles is served by the Southern Pacific, the Atchison, Topeka & Santa Fé, and the San Pedro, Los Angeles & Salt Lake railways; by steamers to San Francisco; and by five systems of urban and suburban electric railways, which have 300 m. of track within the city and 700 m. within a radius of 30 m. beyond its limits. Inclined railways ascend Third Street Hill and Court Street Hill, in the heart of the city; and a system of subways extends from the centre of the city to its western limits. The harbour, San Pedro Bay, originally open and naturally poor, has been greatly improved by the Federal government; a breakwater 9250 ft. long was begun in 1898 and the bar has been deepened, and further improvements of the inner harbour at Wilmington (which is nearly landlocked by a long narrow island lying nearly east and west across its mouth) were begun in 1907. Important municipal docks have been built by the city. + +The situation of the city between the mountains and the sea is attractive. The site of the business district is level, and its plan regular; the suburbs are laid out on hills. Although not specifically a health resort, Los Angeles enjoys a high + +1 They extend, however, to Fiji, Tahiti and Fanning Island. + +2 Unless it be Oreopsittacus arfaki , of New Guinea, remarkable as the only parrot known as yet to have fourteen instead of twelve rectrices. + +3 In addition to the large foreign-born population (4023 Germans, 3017 English, 2683 English Canadians, 1885 Chinese, 1720 Irish and smaller numbers of French, Mexicans, Swedes, Italians, Scots, Swiss, Austrians, Danes, French Canadians, Russians, Norwegians, Welsh and Japanese) 26,105 of the native white inhabitants were of foreign parentage (i.e. had one or both parents not native born), so that only 54,121 white persons were of native parentage. German, French and Italian weekly papers are published in Los Angeles. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg475_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg475_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f92f7ffebc3a5929fc3aea4f1e882619388f8b38 --- /dev/null +++ b/outputs/long_tiny_text/13_pg475_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +his time was the outcome of a lowered morality, not of a clearer spiritual vision."¹ A strong sense of the unique privileges of the children of Jacob, the objects of electing love (i. 2), the children of the Divine Father (ii. 10), is combined with an equally strong assurance of Yahweh's righteousness notwithstanding the many miseries that pressed on the unhappy inhabitants of Judaea. At an earlier date the prophet Haggai had taught that the people could not expect Yahweh's blessing while the Temple lay in ruins. In Malachi's time the Temple was built (i. 10) and the priests waited in their office, but still a curse seemed to rest on the nation's labours (iii. 9). To Malachi the reason of this is plain. The "law of Moses" was forgotten (iv. 4 [iii. 22]); let the people return to Yahweh, and He will return to them. It was in vain to complain, saying, "Every one that doeth evil is good in the eyes of Yahweh," or "Where is the God of judgment?"—vain to ask "Wherein shall we return?" Obedience to the law is the sure path to blessing (ii. 17-iii. 12). + +He calls the people to repentance, and he enforces the call by proclaiming the approach of Yahweh in judgment against the sorcerers, the adulterers, the false swearers, the oppressors of the poor, the orphan and the stranger. Then it shall be seen that He is indeed a God of righteous judgment, distinguishing between those that serve Him and those that serve Him not. The Sun of Righteousness shall shine forth on those that fear Yahweh's name; they shall go forth with joy, and tread the wicked under foot. The conception of the day of final decision, when Yahweh shall come suddenly to His temple (iii. 1) and confound those who think the presumptuous godless happy (iii. 15), is taken from earlier prophets, but is applied wholly within the Jewish nation. The day of Yahweh would be a curse, not a blessing, if it found the nation in its present state: the priests listlessly performing a fraudulent service (i. 7-ii. 9), the people bound by marriage to heathen women, while the tears of the daughters of Israel, thrust aside to make way for strangers, cover the altar (ii. 11-16), all faith in divine justice gone (ii. 17; iii. 14 seq.), sorcery, uncleanness, falsehood and oppression rampant (iii. 5), the house of God deprived of its dues (iii. 8), and the true fearers of God a little flock gathered together in private exercises of religion (perhaps the germ of the later synagogue) in the midst of a godless nation (iii. 16). That the day of Yahweh is delayed in such a state of things is but a new proof of His unchanging love (iii. 6), which refuses to consume the sons of Jacob. Meantime He is about to send His messenger to prepare His way before Him. The prophet Elijah must reappear to bring back the hearts of fathers and children before the great and terrible day of Yahweh come. Elijah was the advocate of national decision in the great concerns of Israel's religion; and it is such decision, a clear recognition of what the service of Yahweh means, a purging of His professed worshippers from hypocritical and half-hearted service (iii. 3) that Malachi with his intense religious earnestness sees to be the only salvation of the nation. In thus looking to the return of the ancient prophet to do the work for which later prophecy is too weak, Malachi unconsciously signals the decay of the order of which he was one of the last representatives; and the somewhat mechanical measure which he applies to the people's sins, as for example when he teaches that if the sacred dues were rightly paid prosperous seasons would at once return (iii. 10), heralds the advent of that system of formal legalism which thought that all religious duty could be reduced to a system of set rules. Yet Malachi himself is no mere formalist. To him, as to the Deuteronomic legislation, the forms of legal observance are of value only as the fitting expression of Israel's peculiar sonship and service, and he shows himself a true prophet when he contrasts the worthless ministry of unwilling priests with the pure offering of prayer and praise that rises from the implicit monotheism of even Gentile worship² (i. 11), or when he asserts + +the brotherhood of all Israelites under their one Father (ii. 10), not merely as a ground of separation from the heathen, but as inconsistent with the selfish and cruel freedom of divorce current in his time.³ The book is a significant landmark in the religious history of Israel. Its emphasis on the observance of ritual finds fullest development in the Priestly Code, subsequently promulgated; its protest against foreign marriages is made effective through the reforms of Ezra and Nehemiah;⁴ the influence of its closing words on later expectation is familiar to every reader of the new Testament.⁵ + +The style of Malachi, like his argument, corresponds in its generally prosaic character to that transformation or decay of prophecy which began with Ezekiel; and Ewald rightly called attention to the fact that the conduct of the argument already shows traces of the dialectic manner of the schools. Yet there is a simple dignity in the manner not unworthy of a prophet, and rising from time to time to poetical rhythm. + +LITERATURE.—Nowack, Die kleinen Propheten (1897; 2nd ed., 1904); Wellhausen, id. (iii. 1898); G. A. Smith, The Book of the Twelve (ii. 1898); A. C. Welch, art. "Malachi" in Hastings's Dict. of the Bible, iii. 218-222 (1900); C. C. Torrey, id. in Ency. Bib. iii. c. 2907-2910 (1902); Marti, Dodekapropheton (1904); Stade, Biblische Theologie des Alten Test. § 141 (1905); Driver, The Minor Prophets, ii. (Century Bible, 1906). (W. R. S.; H. W. R.*) + +MALACHITE, a copper-ore of fine green colour, sometimes polished as an ornamental stone. The name is derived from Gr. μαλάχη, the mallow; in allusion to the colour of the mineral being rather like that of the mallow-leaf. Malachite was perhaps one of the green minerals described by Theophrastus under the general name of σμάρραγδος; and according to the late Rev. C. W. King it was probably the smaragdus medicus of Pliny, whilst his molochites seems to have been a different stone from our malachite and may have been a green jasper. It is suggested by J. L. Myres (Ency. Bib.) that malachite may have been the Heb. soham , of the high priest's breastplate. + +Malachite is a basic cupric carbonate, represented by the formula \(CuCO_3Cu(HO)_2\) , and has usually been formed by the action of meteoric agencies on other copper-minerals; hence it is found in the upper part of ore-deposits, often as an incrustation, and occasionally as a pseudomorph after cuprite, chalco-cite, &c. When formed, as commonly happens, by the alteration of copper-pyrites the iron of this mineral usually takes the form of limonite, which may remain associated with the malachite. Occasionally, though but rarely, malachite occurs in small dark-green prismatic crystals of the monoclinic system. Its usual mode of occurrence is in nodular or stalagmitic forms, with a mammillated, reniform or botryoidal surface, whilst in other cases it forms fibrous, compact or even earthy masses. The nodules, though commonly dull on the outside, may display on fracture a beautiful zonary structure, the successive layers often succeeding each other as curved deposits of light and dark tints. The colours include various shades of apple-green, grass-green, emerald-green and verdigris-green. Certain varieties exhibit a finely fibrous structure, producing on the fractured surface a soft silky sheen. + +Whilst malachite is found in greater or less quantity in most copper-mines, the finer varieties useful for ornamental purposes are of very limited occurrence, and the lapidary has generally drawn his supply from Russia and Australia. The principal source in recent years has been the Medno-Rudiansk mine near Nizhne Tagilsk, on the Siberian side of the Urals, but it was formerly obtained from mines near Bogoslovsk to the north and Gumishev to the south of this locality. A mass from Gumishev, preserved in the museum of the Mining Institute of St Petersburg weighs 3240 lb, and still larger masses have been found near Nizhne Tagilsk. The mineral is prized in + +³ In ii. 16 the Targum renders "If thou hatest her put her away." It is characteristic of later Judaism that an arbitrary exegesis transformed the above anticipation of the doctrine of marriage laid down in the gospel into an express sanction of the right of the husband to put away his wife at will. + +⁴ "The permanence of Judaism depended on the religious separateness of the Jews" (Ryle, Ezra and Nehemiah , p. 143). + +⁵ Matt. xvii. 3, 4, 10-13; xxvii. 47, 49; John i. 21, 25. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg501_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg501_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b6e55bb9df63b7af9ddb6e8c5d71b16f7e99228b --- /dev/null +++ b/outputs/long_tiny_text/13_pg501_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +18th century a raja of the royal house of Menangkabu came from Sumatra to rule over the federation of small states, each of which continued to be governed in all its local affairs by its own chief and by the village and other councils sanctioned by ancient custom. The Sumatran raja took the title of Iang-di-per-Tuan of Sri Menanti. Although they bore the name of the "Nine States," only six seem to have belonged to the federation during the time of which history speaks. These are Sri Menanti, Johol, Tampin, Rembau, Jelebu, and Sungei Ujong. Later the two latter separated themselves from the confederation. Ancient tradition says that the names of the nine states were originally Klang, Jelebu, Sungei Ujong, Johol, Segamat, Pasir Besar, Naning, Rembau and Jelai. Of these Klang was annexed by Selangor, Segamat and Pasir Besar by Johor, and Naning by Malacca. During the last years of the 18th century the Iang-di-per-Tuan appointed an Iang-di-per-Tuan Muda to rule Rembau, and the state of Tampin was created to provide for the family of the new chief. In 1887 the governor of the Straits Settlements sent Mr Martin Lister to the Negri Sembilan, which had become disintegrated, and by his influence the ancient federal system was revived under the control of a Resident appointed by the governor. The states which formed this new confederation were Johol, Ulu Muar, Jempol, Terachi, Inas, Gunong Pasir, Rembau, Tampin and Gemencheh. Prior to this, in 1873, owing to a civil war in Sungei Ujong, Sir Andrew Clarke sent a military force to that state, put an end to the disturbances, and placed the country under the control of a British Resident. Jelebu was taken under British protection in 1886, and was thenceforth managed by a magistrate under the orders of the Resident of Sungei Ujong. In 1896, when the federation of all the Malayan states under British control was effected, Sungei Ujong and Jelebu were reunited to the confederation of small states from which they had so long been separated and the whole, under the old name of the Negri Sembilan, or Nine States, was placed under one Resident. + +The population of the Negri Sembilan, which according to the census taken in April 1891 was only 70,730, had increased to 96,028 by 1901, and was estimated at 119,454 in 1905. Of these 46,500 are Chinese, 65,000 Malays, 6700 Tamils, and 900 Europeans and Eurasians. The births registered slightly exceed the deaths in number, there being a large Malay population in the Negri Sembilan among whom the proportion of women to men is fair, a condition of things not found in localities where the inhabitants are mostly Chinese immigrants. + +The revenue of the Negri Sembilan amounted to only \$223,435 in 1888. In 1898 it had increased to \$701,334, in 1900 to \$1,251,366, and in 1905 to \$2,335,534. The revenue for 1905 was derived mainly as follows:—customs \$1,268,602, land revenue \$145,475, land sales \$21,407, while the revenue farms contributed \$584,459. The expenditure in 1905 amounted to \$2,214,093, of which \$1,125,355 was expended upon public works. The trade returns for 1905, which are not, however, complete, show an aggregate value of about \$13,000,000. The value of the tin exported during 1905 exceeded \$6,900,000, and the value of the agricultural produce, of which gambier represented \$211,000 and damar \$80,000, amounted to \$407,990. + +Seremban, the administrative capital of the Negri Sembilan, is connected with Port Dickson by a railway line, owned by the General Sungei Ujong Railway Company, which is 24\(\frac{1}{2}\) m. in length. It is also situated on the trunk line of the Federated Malay States, and is thus joined by rail to Selangor on the north and to Malacca on the south. Frequent steam communication is maintained between Port Dickson and the ports on the Straits of Malacca and with Singapore. + +For administrative purposes the Negri Sembilan is divided into five districts, viz. the Seremban District, the Coast District, Jelebu, Kuala Pilah and Tampin. Each of these is under the charge of a European district officer, who is responsible to the Resident. The Iang-di-per-Tuan lives at Kuala Pilah, but the capital of the federation is at Seremban in Sungei Ujong, where the Resident is stationed. The hereditary chiefs of the various states aid in the government of their districts, and have seats upon the state council, over which the Iang-di-per-Tuan presides. The watering-place of Magnolia Bay, where excellent sea-bathing is obtainable, is one of the pleasure resorts of this part of the peninsula. + +PAHANG, on the east coast of the peninsula, is situated between parallels 2°28' and 3°45' N. and 101°30' and 103°30' E. It is bounded on the N. by the independent native states of Kelantan and Trengganu; on the S. by the Negri Sembilan and Johor; on the E. by the China Sea; and on the W. by the protected states of Perak and Selangor. The coast-line is about 112 m. in length; the greatest length is about 210 m., and greatest breadth about 130 m. The state is the largest in the peninsula, its area being estimated at 15,000 sq. m. The ports on the coast are the mouths of the Endau, Rompin, Pahang and Kuantan rivers, but during the north-east monsoon the coast is not easy of approach, and the rivers, all of which are guarded by difficult bars, are impossible of access except at high tides. + +The principal river of the state is the Pahang, from which it takes its name. At a distance of 180 m. from the coast this river is formed by two others named respectively the Jelai and the Tembeling. The former is joined 20 m. farther up stream by the Lipis, which has its rise in the mountains which form the boundary with Perak. The Jelai itself has its rise also in a more northerly portion of this range, while its two principal tributaries above the mouth of the Lipis, the Telom and the Serau, rise, the one in the plateau which divides Perak from Pahang, the other in the hills which separate Pahang from Kelantan. The Tembeling has its rise in the hills which divide Pahang from Kelantan, but some of its tributaries rise on the Trengganu frontier, while the largest of its confluents comes from the hills in which the Kuantan River takes its rise. The Pahang is navigable for large boats as far as Kuala Lipis, 200 m. from the mouth, and light-draught launches can also get up to that point. Smaller boats can be taken some 80 m. higher up the Jelai and Telom. The river, however, as a waterway is of little use, since it is uniformly shallow. The Rompin and Kuantan rivers are somewhat more easily navigated for the first 30 m. of their course, but taken as a whole the waterways of Pahang are of little value. The interior of Pahang is chiefly noted for its auriferous deposits. Gunong Tahan is situated on the boundary between Pahang and Kelantan. Its height is estimated at 8000 ft. above sea-level, but it has never yet been ascended. Pahang, like the states on the west coast, is covered almost entirely by one vast forest, but in the Lipis valley, which formerly was thickly populated, there is a considerable expanse of open grass plain unlike anything to be seen on the western sea-board. The coast is for the most part a sandy beach fringed with casuarina trees and there are only a few patches of mangrove-swamp throughout its entire length. + +The ancient name of Pahang was Indrapura. It is mentioned in the history of Hang Tuah, the great Malacca brave, who flourished in the 16th century, and succeeded in abducting a daughter History. of the then ruling house of Pahang for his master, the sultan of Malacca. Prior to this, Pahang had been ruled by the Siamese. When Malacca fell into the hands of the Portuguese in 1511 the sultan, Muhammad Shah, fled to Pahang, and the present ruling house claims to have been descended from him. The title of the ruler of Pahang was Bendahara until 1882, when the present (1902) ruler, Wan Ahmad, assumed the title of sultan, taking the name of Sultan Ahmad Maatham Shah. Up to that time the Bendahara had been installed on his accession by the sultan of Riau, and held his office by virtue of that chief's letter of authority. About 1855 the father of the present sultan died at Pekan, and his son Bendahara Korish, who succeeded him, drove Wan Ahmad from the country. After making three unsuccessful attempts to conquer the land and to dethrone his elder brother, Wan Ahmad at last succeeded in 1865 in invading the state and wrestling the throne from his nephew, who had succeeded his father some years earlier. From that time, in spite of two attempts to shake his power by invasions from Selangor which were undertaken by his nephews Wan Aman and Wan Da, Bendahara Ahmad ruled his country with a rod of iron. In 1887 he consented to enter into a treaty with the governor of the Straits by which he accepted a consular agent at his court. This treaty was finally signed on the 8th of October 1887. In February of the following year a Chinese British subject was murdered at Pekan in circumstances which pointed to the responsibility of the sultan for the crime, and in October 1888 a Resident was appointed to assist the sultan in the administration of his country, that being, in the opinion of the British government, the only guarantee for the safety of the life and property of British subjects which it could accept. In December 1891 disturbances broke out in Pahang, the nominal leaders of which were certain of the sultan's most trusted chiefs. The sultan himself took no part in the outbreak, but it undoubtedly had his sympathy, even if it was not caused by his direct commands. The rebels were driven to seek safety in flight in November 1892, but in June 1894 they gathered strength for a second disturbance, and raided Pahang from Kelantan, in which state they had been given shelter by the Mahomedan rulers. This event, added to the occurrence of other raids from across the border, led to an irregular expedition being led into Trengganu and Kelantan by the Resident of Pahang (Mr Hugh Clifford) in 1895, and this had the desired result. The rebel chiefs were banished to Siam, and no further breach of the peace has troubled the tranquility of Pahang since that time. Pahang joined the Federated Malay States by a treaty signed in 1895, and the sultan and his principal chiefs were present at the federal durbar held at Kuala Kangsar in Perak in 1897. + +The census taken in April 1901 gave the total population of Pahang at 84,113, of whom 73,462 were Malays, 8695 Chinese, 1227 Tamils and other natives of India, 180 Europeans and Eurasians, and 549 people of other nationalities. The population in 1905 was estimated at 100,000, the increase being due to immigration mainly from the states on the western seaboard. In former days Pahang was far more thickly populated than in modern times, but the long succession of civil wars which racked the land after the death of Bendahara Ali caused thousands of Pahang Malays to fly the country. To-day the valley of the Lebir River in Kelantan and the upper portions of several rivers near the Perak and Selangor + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg531_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg531_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..79ae743a1d53d3c4c0fe78c526c58223919a9e69 --- /dev/null +++ b/outputs/long_tiny_text/13_pg531_pg1_pg1_repeat1.md @@ -0,0 +1,11 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Carthaginian times, continued in Malta under the Romans. The Phoenician temple of Juno, which stood on the site of Fort St Angelo, is also mentioned by Valerius Maximus. An inscription records the restoration of the temple of Proserpine by Cheriston, a freed-man of Augustus and procurator of Malta. Diodorus Siculus (L. V., c. 4) speaks of the importance and ornamentation of Maltese dwellings, and to this day remains of palaces and dwellings of the Roman period indicate a high degree of civilization and wealth. When forced to select a place of exile, Cicero was at first (ad Au. III. 4, X. i. 8, 9) attracted to Malta, over which he had ruled as quaestor 75 B.C. Among his Maltese friends were Aulus Licinius and Diodorus. Lucius Castricius is mentioned as a Roman governor under Augustus. Publius was "chief of the island" when St Paul was shipwrecked (Acts xxvii. 7); and is said to have become the first Christian bishop of Malta. The site where the cathedral at Notabile now stands is reputed to have been the residence of Publius and to have been converted by him into the first Christian place of worship, which was rebuilt in 1090 by Count Roger, the Norman conqueror of Malta. The Maltese catacombs are strikingly similar to those of Rome, and were likewise used as places of burial and-of refuge in time of persecution. They contain clear indication of the interment of martyrs. St Paul's Bay was the site of shipwreck of the apostle in A.D. 58; the "topon diathalasson" referred to in Acts is the strait between Malta and the islet of Selmun. The claim that St Paul was shipwrecked at Meleda off the Dalmatian coast, and not at Malta, has been clearly set at rest, on nautical grounds, by Mr Smith of Jordanhill (Voyage and Shipwreck of St Paul, London, 1848). According to tradition and to St Chrysostom (Hom. 54) the stay of the apostle resulted in the conversion of the Maltese to Christianity. The description of the islanders in Acts as "barbaroi" confirms the testimony of Diodorus Siculus that they were Phoenicians, neither hellenized nor romanized. The bishopric of Malta is referred to by Rocco Pirro (Sicilia sacra), and by Gregory the Great (Epist. 2, 44; 9, 63; 10, 1). It appears that Malta was not materially affected by the Greek schism, and remained subject to Rome. + +On the final division of the Roman dominions in A.D. 395 Malta was assigned to the empire of Constantinople. On the third Arab invasion, A.D. 870, the Maltese joined forces against the Byzantine garrison, and 3000 Greeks were massacred. Unable to garrison the island with a large force, the Arabs cleared a zone between the central stronghold, Medina, and the suburb called Rabat, to restrict the fortified area. Many Arab coins, some Kufic inscriptions and several burial-places were left by the Arabs; but they did not establish their religion or leave a permanent impression on the Phoenician inhabitants, or deprive the Maltese language of the characteristics which differentiate it from Arabic. There is no historical evidence that the domination of the Goths and Vandals in the Mediterranean ever extended to Malta: there are fine Gothic arches in two old palaces at Notabile, but these were built after the Norman conquest of Malta. In 1090 Count Roger the Norman (son of Tancred de Hauteville), then master of Sicily, came to Malta with a small retinue; the Arab garrison was unable to offer effective opposition, and the Maltese were willing and able to welcome the Normans as deliverers and to hold the island after the immediate withdrawal of Count Roger. A bishop of Malta was witness to a document in 1090. The Phoenician population had continued Christian during the mild Arab rule. Under the Normans the power of the Roman Church quickly augmented, tithes were granted, and ecclesiastical buildings erected and endowed. The Normans, like the Arabs, were not numerically strong; the rule of both, in Sicily as well as Malta, was based on a recognition of municipal institutions under local officials; the Normans, however, exterminated the Mahommedans. Gradually feudal customs asserted themselves. In 1193 Margarito Brundusio received Malta as a fief with the title of count; he was Grand Admiral of Sicily. Constance, wife of the emperor Henry IV. of Germany became, in 1194, heiress of Sicily and Malta; she was the last of the Norman dynasty. The Grand Admiral of Sicily + +in 1223 was Henry, count of Malta. He had led 300 Maltese at the capture of two forts in Tripoli by the Genoese. In 1265 Pope Alexander IV. conferred the crown of Sicily on Charles of Anjou to the detriment of Manfred, from whom the French won the kingdom at the battle of Benevento. Under the will of Corradino a representative of the blood of Roger the Norman, Peter of Aragon claimed the succession, and it came to him by the revolution known as "the Sicilian Vespers" when 28,000 French were exterminated in Sicily. Charles held Malta for two years longer, when the Aragonese fleet met the French off Malta, and finally crushed them in the Grand Harbour. In 1427 the Turks raided Malta and Gozo, they carried many of the inhabitants into captivity, but gained no foothold. The Maltese joined the Spaniards in a disastrous raid against Gerbi on the African coast in 1432. In 1492 the Aragonese expelled the Jews. Dissatisfaction arose under Aragonese rule from the periodical grants of Malta, as a marquisate or countship, to great officers of state or illegitimate descendants of the sovereign. Exemption was obtained from these incidences of feudalism by large payments to the Crown in return for charters covenanting that Malta should for ever be administered under the royal exchequer without the intervention of intermediary feudal lords. This compact was twice broken, and in 1428 the Maltese paid King Alfonso 30,000 florins for a confirmation of privileges, with a proviso that entitled them to resist by force of arms any intermediate lord that his successors might attempt to impose. Under the Aragonese, Malta, as regards local affairs, was administered by a Università or municipal commonwealth with wide and indefinite powers, including the election of its officers, Capitan di Verga, Jurats, &c. The minutes of the "Consiglio Popolare" of this period are preserved, showing it had no legislative power; this was vested in the king, and was exercised despotically in the interests of the Crown. The knights of St John having been driven from Rhodes by the Turks, obtained the grant of Malta, Gozo and Tripoli in 1530 from the emperor Charles V., subject to a reversion in favour of the emperor's successor in the kingdom of Aragon should the knights leave Malta, and to the annual tribute of a falcon in acknowledgment that Malta was under the suzerainty of Spain. The Maltese, at first, challenged the grant as a breach of the charter of King Alfonso, but eventually welcomed the knights. The Grand Master de l'Isle Adam, on entering the ancient capital of Notabile, swore for himself and his successors to maintain the rights and liberties of the Maltese. The Order of St John took up its abode on the promontory guarded by the castle of St Angelo on the southern shore of the Grand Harbour, and, in expectation of attacks from the Turks, commenced to fortify the neighbouring town called the Borgo. The knights lived apart from the Maltese, and derived their principal revenues from estates of the Order in the richest countries of Europe. They accumulated wealth by war, or by privateering against the Turks and their allies. The African Arabs under Selim Pasha in 1551 ravaged Gozo, after an unsuccessful attempt on Malta, repulsed by cavalry under Upton, an English knight. The Order of St John and the Christian Maltese now realized that an attempt to exterminate them would soon be made by Soliman II., and careful preparations were made to meet the attack. + +The great siege of Malta which made the island and its knights famous, and checked the advance of Mahommedan power in southern and western Europe, began in May 1565. The fighting men of the defenders are variously recorded between 6100 and 9121; the roll comprises one English knight, Oliver Starkey. The Mahommedan forces were estimated from 29,000 to 38,500. Jehan Parisot de la Valette had participated in the defence of Rhodes, and in many naval engagements. He had been taken prisoner by Dragut, who made him row for a year as a galley slave till ransomed. This Grand Master had gained the confidence of Philip of Spain, the friendship of the viceroy of Sicily, of the pope and of the Genoese admiral, Doria. The Sultan placed his troops under the veteran Mustapha, and his galleys under his youthful relative Piali, he hesitated to make either supreme and ordered them to await the arrival of Dragut with + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg556_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg556_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..87e98cd3e7f6e3183a254a7b87701cc58fb2446c --- /dev/null +++ b/outputs/long_tiny_text/13_pg556_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +the local demand in the summer, though some of the fish named are exported during the rest of the year. About 250 vessels, aggregating 4260 tons, with crews numbering 4250, are employed in this industry. A fish hatchery has been established at Port Erin by the insular government. + +(c) Mining.—There is no doubt that, in proportion to its area, the metalliferous wealth of the Isle of Man has been very considerable. Two of its mines, Laxey and Foxdale, have stood for a long series of years in the first rank in the British Islands for productiveness of zinc and silver lead respectively. These metals have constituted its principal riches, but copper pyrites and hematite iron have also been raised in marketable quantities, while only very small amounts of the ores of nickel and antimony have been found. The mines are rented from the Crown as lord of the manor. The value of the ore produced is about £40,000 annually. Other economic products are clay, granite, limestone, sandstone, slate (of an inferior quality) and salt, which has been discovered near the Point of Ayre. + +(d) Textiles, &c.—Since labour has become scarcer and dearer textile industries have been declining, being unable to compete with larger and more completely organized manufactorys elsewhere. The principal manufactured articles are woollen cloths and blankets, hemp ropes and cotton, and herring nets. A few fishing vessels are built, and brewing is a prosperous industry. But, apart from agriculture, the most important industry (for so it may be called) is that of the provision for summer visitors, nearly half a million of whom come to the island annually. + +Commerce.—The chief exports are lead, zinc, turnips, ropes, cotton nets and salt. The imports consist chiefly of timber, provisions, live-stock, poultry, flour, fruit, vegetables and eggs. In 1906 the tonnage of vessels (other than fishing or wind-bound vessels) cleared for traffic was 720,790. The number of vessels (other than fishing vessels) registered as belonging to the island in 1906 was 79. + +Government.—The government of the island is vested in a lieutenant-governor, appointed by the Crown; in a Council, which is the upper branch of the legislature; in the House of Keys, which is the lower branch; and in the Tynwald Court. The Council and Keys sit separately as legislative bodies, but they sit in the Tynwald Court as distinct bodies with co-ordinate powers to transact executive business and to sign Bills. The Tynwald Court controls the surplus revenue, after the payment of the cost of government and of a fixed contribution of £10,000 to the imperial exchequer, subject to the supervision of the Treasury and the veto of the lieutenant-governor, and it appoints boards to manage the harbours, highways, education, local government, and lunatic and poor asylums. The Imperial government, after intimating its intention to Tynwald, fixes the rates of the customs duties, but Tynwald can by resolution "impose, abolish or vary" the customs duties subject to the approval of parliament or the Treasury, such change to take effect immediately and to continue for six months, and, if parliament be then sitting, to the end of the session, provided that the same be not in the meantime annulled by the passing of an act of parliament, or a Treasury minute. The approval of the sovereign of the United Kingdom in Council is essential to every legislative enactment. Acts of the imperial parliament do not affect the island except it be specially named in them. The lieutenant-governor, who is the representative of the sovereign, presides in the Council, in the Tynwald Court, in the High Court of Justice (Staff of Government division) and in the Court of General Gaol Delivery. He is the supreme executive authority, and he shares the control of the legislative and administrative functions, including the management of the revenue and the control of its surplus, with the Tynwald Court; he has also the power of veto as regards the disposal of surplus revenue and the nature of proposed harbour works, and his signature is necessary to the validity of all acts. It has been the practice for him to act as chancellor of the exchequer and to initiate all questions concerning the raising or expenditure of public funds. The Council consists of the lieutenant-governor, the lord-bishop of the diocese, the clerk of the rolls, the two deemsters, the attorney-general, the archdeacon (all of whom are appointed by the Crown) and the vicar-general, who is appointed by the bishop. No act of the governor and Council is valid unless it is the act of the governor and at least two members of the Council. The House of Keys (for origin of the name see KEY) is one of the most ancient legislative assemblies in the world. It consists of twenty-four members, elected by male and female owners or + +occupiers of property. Each of the six shedings elects three members; the towns of Castletown, Peel and Ramsey one each, and Douglas five. There is no property qualification required of the members, and the house sits for five years unless previously dissolved by the lieutenant-governor. + +Law.—The High Court of Justice, of which the lieutenant-governor is president, contains three divisions: viz. the Chancery Division, in which the clerk of the rolls sits as judge, the Common Law Division, of which the deemsters are the judges, the Staff of Government Division, in which the governor and three judges sit together. The jurisdiction of the Chancery and Common Law Division is in the main similar to that of the corresponding divisions in the English Courts. The Staff of Government exercises appellate jurisdiction, similar to that of the Appeal Courts in England. The Common Law Courts for the southern division of the island are held at Douglas and Castletown alternately and those for the northern division at Ramsey, once in three months. Actions in these courts are heard by a deemster and a special or common jury. The Chancery Court sits once a fortnight at Douglas. The deemsters also have summary jurisdiction in matters of debt, actions for liquidated damages under £50, suits for possession of real or personal property, petitions for probate, &c. These courts, called Deemsters' Courts, are held weekly, alternately at Douglas and Castletown, by the deemster for the southern division of the island, and at Ramsey and Peel by the deemster for the northern division. Criminal cases are heard by the magistrates or a high-bailiff and are (with the exception of minor cases which may be dealt with summarily) sent on by them for trial by a deemster and a jury of six; who hear the evidence and determine whether there is sufficient ground for sending the case for trial before the Court of General Gaol Delivery, thus discharging the functions of the Grand Jury in England. The Court of General Gaol Delivery is the Supreme Criminal Court and is presided over by the lieutenant-governor, who is assisted by the clerk of the rolls and the two deemsters. The high-bailiffs hold weekly courts in the four towns for the recovery of debts under forty shillings and for the trial of cases usually brought before a stipendiary magistrate in England. The magistrates (J.P.'s) also hold regular courts in the towns for the trial of breaches of the peace and minor offences. There is a coroner in each of the six shedings. These officers are appointed annually by the lieutenant-governor and perform duties similar to those of a sheriff's officer in England. Inquests of death are held by a high-bailiff and jury. The Manx Bar is distinct from that of England. Its members, called "Advocates," combine the functions of barrister and solicitor. The laws relating to real property still retain much of their ancient peculiarity, but other branches of law have of late years by various acts of Tynwald been made practically identical with English law. + +As regards real property the general tenure is a customary freehold devolving from each possessor to his next heir-at-law. The descent of land follows the same rules as the descent of the crown of England. The right of primogeniture extends to females in default of males in the direct line. The interest of a widow or widower, being the first wife or husband of a person deceased, is a life estate in one-half of the lands which have descended hereditarily, and is forfeited by a second marriage; a second husband or second wife is only entitled to a life interest in one-fourth, if there be issue of the first marriage. Of the land purchased by the husband the wife surviving him is entitled to a life interest in one moiety. By a statute of the year 1777 proprietors of land are empowered to grant leases for any term not exceeding twenty-one years in possession without the consent of the wife. + +Church.—It is not known by whom Christianity was introduced into Man, but from the large proportion of names of Irish ecclesiastics surviving in the appellations of the old Manx keeills, or cells, which are of similar type to the Irish oratories of the 6th and 7th centuries, and in the dedications of the parish churches, which are usually on ancient sites, it may be reasonably conjectured that Manxmen were, for the most part, Christianized by Irish missionaries. During the incursions of the pagan Vikings Christianity was almost certainly extirpated and it was probably not reintroduced before the beginning of the 11th century. The two most important events in the history of the medieval Manx Church were the formation of the diocese of Sodor (q.v.) and the foundation of the abbey of Rushen, a branch of the Cistercian abbey of Furness, in 1134. This latter event was important because the Cistercians were exempted from all episcopal visitation and control, by charter granted by the pope, and were, therefore, only subject to his rule and that of the abbots of their own order. From this time till the Reformation we find that there was an almost continuous struggle between the laity and the spiritual barons and monks, who had obtained great power and much property in the island. In 1458 the diocese was placed under York. The dissolution of the religious houses in Man was not brought about by the English Act of 1539, which did not apply to the island, but by the arbitrary action of Henry VIII. From such evidence as is available it would seem that the Reformation was a very slow process. When Isaac Barrow (uncle of his well-known namesake) became bishop in 1663 the condition of the Church was deplorable, but under him and his able and saintly successors, Thomas + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg566_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg566_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..59f2dfbf398ce3c2bb3b1ef383310a8f73b2ca7c --- /dev/null +++ b/outputs/long_tiny_text/13_pg566_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +by Ford Madox Brown, illustrating the history and progress of the city. The royal exchange is a fine specimen of Italian architecture and was erected in 1869; the great meeting-hall is one of the largest rooms in England, the ceiling having a clear area, without supports, of 120 ft. in width. The exchange is seen at its best on market days (Tuesday and Friday). The assize courts were built in 1864 from designs by Waterhouse. The style is a mixture of Early English and Decorative, and a large amount of decorative art has been expended on the building. The branch Bank of England is a Doric building designed by C. R. Cockerell. There are separate town-halls for the townships of Ardwick, Chorlton, Hulme, Cheetham, Broughton and Pendleton. The Free Trade hall is a fine structure in the Lombardo-Venetian style, and its great hall will accommodate about five thousand people. It is used for public meetings, concerts, &c., and was built by Edward Walters. The Athenaeum, designed by Barry, was founded by Richard Cobden and others associated with him for "the advancement and diffusion of knowledge." The institution has, perhaps, not developed exactly on the lines contemplated by its promoters, but it has been very useful. The advantages enjoyed by members of social clubs, with the addition of facilities for educational classes and the use of an excellent newsroom and a well-selected library, are offered in return for a payment which does not amount to a penny a day. The mechanics' institution has developed into the school of Technology, which now forms a part of the university. The Portico is a good specimen of the older proprietary libraries and newsrooms. It dates from 1806, and has a library. The Memorial Hall was built to commemorate the memory of the ejected ministers of 1662; it is used for meetings, scientific, educational, musical and religious. The Whitworth Institute is governed by a corporate body originating from the liberal bequests of Sir Joseph Whitworth. The Institute contains a valuable collection of works of art and stands in the centre of a woodland park. In the park, which has been transferred to the corporation, is a sculpture group of "Christ and the Children," executed by George Tinworth from the designs of R. D. Darbshire, by whom it was presented. The assize courts, built from designs by Waterhouse (1864), the post office (1887), and the police courts (1891) should also be named. Many fine structures suffer from being hemmed in by streets which prevent the proportions from being seen to advantage. + +Monuments.—In Piccadilly are bronze statues of Wellington, Watt, Dalton, Peel and Queen Victoria. Another statue of the Queen, by the Princess Louise, is placed on the new porch of the cathedral. A bronze statue of Cobden occupies a prominent position in St Ann's Square. There also is the South African War Memorial of the Manchester Regiment. The marble statue of the Prince Consort, covered by a Gothic canopy of stone, is in front of the town hall, which dwarfs what would otherwise be a striking monument. In Albert Square there are also statues of Bishop Fraser, John Bright, Oliver Heywood and W. E. Gladstone. A statue of J. P. Joule is in the town hall, which also contains memorials of other worthies. The Queen's Park has a statue of Benjamin Brierley, a well-known writer in the Lancashire dialect. The most picturesque is Matthew Noble's bronze statue of Cromwell, placed on a huge block of rough granite as pedestal. It stands at the junction of Deansgate and Victoria Street, near the cathedral, and was presented to the town by Mrs E. S. Heywood. + +Education.—There are many educational facilities. The oldest institution is the grammar school, which was founded in 1519 by Hugh Oldham, bishop of Exeter, a native of the town. The master and usher appointed by the bishop were to teach freely every child and scholar coming to the school, "without any money or reward taken"; and the bishop forbade the appointment of any member of the religious orders as head master. Some corn mills were devised for the maintenance of the school, which was further endowed at both the universities by Sarah, duchess of Somerset, in 1692. The school has now two hundred and fifty free scholars, whilst + +other pupils are received on payment of fees. Among those educated at the grammar school were Thomas De Quincey, Harrison Ainsworth and Samuel Bamford the Radical. After the grammar school the oldest educational foundation is that of Humphrey Chetham, whose bluecoat school, founded in 1653, is housed in the building formerly occupied by the college of clergy. This also contains the public library founded by Chetham, and is the most interesting relic of antiquity in the city. The educational charity of William Hulme (1631-1691) is administered under a scheme drawn up in 1881. Its income is nearly £10,000 a year, and it supports a grammar school and aids education in other ways. There are three high schools for girls. The Nicholls hospital was founded in 1881 for the education of orphan boys. Manchester was one of the first places to adopt the powers given by Forster's Act of 1870, and on the abolition of school boards the educational supervision was transferred to a committee of the corporation strengthened by co-opted members. In addition to the elementary schools, the municipality provides a large and well-equipped school of technology, and a school of art to which is attached an arts and crafts museum. There are a pupil teachers' college, a school of domestic economy, special schools for feeble-minded children, and a Royal College of Music. The schools for the deaf and dumb are situated at Old Trafford, in a contiguous building of the same Gothic design as the blind asylum, to which Thomas Henshaw left a bequest of £20,000. There is also an adult deaf and dumb institution, containing a news-room, lecture hall, chapel, &c., for the use of deaf mutes. + +The Victoria University of Manchester has developed from the college founded by John Owens, who in 1846 bequeathed nearly £100,000 to trustees for an institution in which should be taught "such branches of learning and science as were then or might be hereafter usually taught in English universities." It was opened in 1851 in a house which had formerly been the residence of Cobden. In 1872 a new college building was erected on the south side of the town from designs by Waterhouse. In 1880 a university charter was granted, excluding the faculties of theology and medicine, and providing for the incorporation of University College, Liverpool, and the College of Science, Leeds. The federal institution thus created lasted until 1903, when the desire of Liverpool for a separate university of its own led to a reconstruction. Manchester University consists of one college—Owens College—in its greatly enlarged form. The buildings include the Whitworth Hall (the gift of the legates of Sir Joseph Whitworth), the Manchester Museum and the Christie Library, which is a building for the university library given by R. C. Christie, who also bequeathed his own collection. Dr Lee, the first bishop of Manchester, left his library to Owens College, and the legates of Sir Joseph Whitworth bought and presented E. A. Freeman's books. The library has received other important special collections. The benefactions to the university of Thomas Ashton are estimated at £80,000. There are in Manchester a number of denominational colleges, Wesleyan, Primitive Methodist, Unitarian, Baptist, &c., and many of the students preparing for the ministry receive their arts training at the university, the theological degrees of which are open to students irrespective of creed. + +Libraries, Museums and Societies.—Manchester is well provided with libraries. The Chetham library, already named, contains some rare manuscripts, the gem of the collection being a copy of the historical compilation of Matthew Paris, with corrections in the author's handwriting. There is a large collection of matter relating to the history and archaeology of Lancashire and Cheshire, including the transcripts of Lancashire MSS. bequeathed by Canon F. R. Raines. The collections of broadsides formed by Mr J. O. Halliwell-Phillipps, and the library of John Byrom, rich in mystics and shorthand writers, should also be named. The Manchester Free Libraries were founded by Sir John Potter in 1852. There is now a reference library containing about 170,000 volumes, including an extensive series of English historical works, a remarkable collection of books of political economy and trade, and special collections relating to local history, Dr Thomas Fuller, shorthand and the gipsies. The + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg639_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg639_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5956cda0fe86a319ab246dbc2532272c6419e45c --- /dev/null +++ b/outputs/long_tiny_text/13_pg639_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +subsequently in the middle ages, we have to deal with it in two forms. The common form of the book of the ancient world was the roll , composed of one continuous sheet of material and inscribed only on one side. This form had a long career. In Egyptian literature it can be traced back for thousands of years. In Greek literature it may be assumed to have been in vogue from the earliest times; actual examples have survived of the latter part of the 4th and beginning of the 3rd centuries B.C. As to its early use in Latin literature we cannot speak so definitely; but Rome followed the example of Greece in letters, and therefore no doubt also in the material shape of literary productions. Both in Greek and Latin literature the roll lasted down to the early centuries of the Christian era. It was superseded by the codex , the manuscript in book form (in the modern sense of the word book), composed of separate leaves stitched together into quires and made available to receive writing on both sides of the material. This form is still in vogue as the modern printed book, and probably will never be superseded. But the codex in this developed shape was only an evolution from the early waxen tablets of the Greeks and Romans, two or more of which, hinged together, formed the primitive codex which suggested the later form. Therefore it will be necessary to include the description of the tablets with that of the later codex. + +The ordinary terms in use among the Greeks for a book (that is, a roll) were βιβλός (another, form of βύβλός, papyrus) and The Roll. its diminutive βιβλιον , which included the idea of a + +written book. The corresponding Latin terms were liber and libellus; volumen was a rolled-up roll. A roll of material uninscribed was χάρτης , charta , or τόπος (originally a cutting of papyrus), applicable also to a roll containing a portion or division of a large work which extended to more than one roll. A work contained within the compass of a single roll was α μονόβιβλός , or μονόβιβλον . The term τεύχος seems also to have meant a single roll, but it was also applied at a later time to indicate a work contained in several rolls. + +In writing the text of a work, the scribe might choose to make use of separate sheets of papyrus, κολλήματα , schedae , and then join them to one another consecutively so as to make up the roll; or he might purchase from the stationers a scapus , or ready-made roll of twenty sheets at most; and if this length were not sufficient, he might add other sheets or scapi , and thus make a roll of indefinite length. But proverbially a great book was a great evil, and, considering the inconvenience of unrolling a long roll, not only for perusal, but, still more so, for occasional reference, the practice of subdividing lengthy works into divisions of convenient size, adapted to the capacity of moderate-sized rolls, must have come into vogue at a very early period. + +It was the practice to write on one side only of the papyrus; to write on both front and back of a roll would obviously be a clumsy and irritating method. Works intended for the market were never opisthograph . Of course the blank backs of written rolls which had become obsolete might be turned to account for personal or temporary purposes, as we learn not only from references in classical authors but also from actual examples. The most interesting extant case of an opisthograph papyrus is the copy of Aristotle's Constitution of Athens in the British Museum, which is written on the back of a farmer's accounts, of the end of the 1st century—but only for private use. It being the rule, then, to confine the writing to one side of the material, that is, to the inner surface of the made-up roll, that surface was more carefully prepared and smoothed than the other; and, further, the joints of the several sheets were so well made that they offered no obstacle to the action of the pen. Still further, care was taken that this, the recto surface of the material, should be that in which the shreds of papyrus of which it was composed lay horizontally, so that the pen might move freely along the fibres; the shreds of the verso side, on the other hand, being in vertical position. This point is of some importance, as, in cases where two different handwritings are found on the two sides of a papyrus, it may be usually assumed that the one on the recto surface is the earlier. + +The text was written in columns, σελίδες , paginae , the width of which seems not to have been prescribed, but which for calligraphic effect were by preference made narrow, sufficient margins being left at head and foot. The average width of the columns in the best extant papyri ranges from two to three-and-a-half inches. The written lines were parallel with the length of the roll, so that the columns stood, so to say, with the height of the rolled-up roll, and were disclosed consecutively as the roll was unwound. Ruling with lead to guide the writing is mentioned by writers, but it does not appear that the practice was generally followed. The number of lines in the several columns of extant papyri is not constant, nor is the marginal boundary of the beginnings of the lines, for the accuracy of which a ruled vertical line would have proved useful, ordinarily kept even. No doubt in practice the horizontal fibres of the material were found to afford a sufficient guide for the lines of writing. + +If the title of the work was to be given, the scribe appears to have written it ordinarily at the end of the text. But something more was needed. To be obliged to unroll a text to the end, in order to ascertain the name of the author, would be the height of inconvenience. Its title was therefore sometimes written at the head of the text. It appears also that at an early period it was inscribed on the outside of the roll, so as to be visible as the roll lay in a chest or on the shelf. But a more general practice was to attach to the top edge of the roll a label or ticket, σελιυβος , or στρυβος , titulus , index , which hung down if the roll lay on the shelf, or was conveniently read if the roll stood along with others in the ordinary cylindrical roll-box, κίστη , κιβάρος , cista , capsa . One such label made of papyrus has survived and is in the British Museum. + +The scribe would not commence his text at the very beginning, nor would he carry it quite down to the end, of the roll. He would leave blank a sufficient length of material at either extremity, where the roll would naturally be most exposed to wear and tear by handling in unrolling and re-rolling; and, further, the extreme vertical edges might each be strengthened by the addition of a strip of papyrus so as to form a double thickness of material. + +According to the particulars given by classical authors, the roll would be finished off somewhat elaborately; but the details described by them must be taken to apply to the more expensive productions of the book trade, corresponding with the full-bound volumes of our days. In practice, a large proportion of working copies and ordinary editions must have been dealt with more simply. Firstly, the roll should be rolled up round a central stick, of wood or bone, called the ὁμφαλός , umbilicus , to which the last sheet of the papyrus may or may not have been attached. But as a matter of fact no rolling-sticks have been found in company with extant papyri, and it has therefore been suggested that they were not attached to the material but were rolled in loose, and were therefore liable to drop out. In some instances, as in the rolls found at Herculaneum, a central core of papyrus instead of a stick was thought sufficient. The edges, frontes , of the roll, after it had been rolled up, were shorn and were rubbed smooth with pumice, and they were sometimes coloured. A valuable roll might be protected with a vellum wrapper, φαινδλός , paenula , stained with colour; and, further, it might be secured with ornamental thongs. The central stick might also be adorned with knobs or "horns," plain or coloured. This seems to be the natural explanation of the κέρα , or cornua , mentioned by the ancient writers. Finally, the title-label described above was attached to the completed roll, now ready for the book-market. + +In the perusal of a work the reader held the roll upright and unrolled it gradually with the right hand; with the left hand he rolled up in the reverse direction what he had read. Thus, when he had finished, the roll had become reversed, the beginning of the text being now in the centre of the roll and the end of it being outside. The roll was "explicitus ad umbilicum," or "ad sua cornua." It had therefore now to be unrolled afresh and to be re-rolled into its normal shape—a troublesome process which the lazy man shirked, and which the careful man + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg67_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg67_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1e0c1c1fdaa6fbe9e7c0a05a2a7a3e95c13529c4 --- /dev/null +++ b/outputs/long_tiny_text/13_pg67_pg1_pg1_repeat1.md @@ -0,0 +1,33 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +dévoilées ou Louis XVII. . . (3 vols., Rotterdam, 1846–1848); O. Friedrichs, Correspondance intime et inédite de Louis XVII. (Naundorff) 1834–1838 (2 vols., 1904); Plaidoirie de Jules Favre devant la cour d'appel de Paris pour les héritiers de feu Charles-Guillaume Naundorff (1874); H. Provins, Le Dernier roi légitime de France (2 vols., the first of which consists of destructive criticism of Beauchesne and his followers, 1889); A. Lanne, "Louis XVII. et le secret de la Révolution," Bulletin mensuel (1893 et seq.) of the Société des études sur la question Louis XVII., also La Légitimité (Bordeaux, Toulouse, 1883–1898). See further the article "Naundorff" in M. Tourneux, Bibl. de la ville de Paris pendant la Révolution, vol. iv. (1906). + +Williams.—J. H. Hanson, The Lost Prince: Facts tending to prove the Identity of Louis XVII. of France and the Rev. Eleazer Williams (London and New York, 1854). + +De Richemont.—Mémoires du duc de Normandie, fils de Louis XVI., écrits et publiés par lui-même (Paris, 1831), compiled, according to Quérard, by E. T. Bourg, called Saint Edme; Morin de Guérevière, Quelques souvenirs . . . (Paris, 1832); and J. Suvigny, La Restauration convaincue . . . ou preuves de l'existence du fils de Louis XVI. (Paris, 1851). + +The widespread interest taken in Louis XVII. is shown by the fact that since 1905 a monthly periodical has appeared in Paris on this subject, entitled Revue historique de la question Louis XVII., also by the promised examination of the subject by the Société d'Histoire contemporaine. (M. Br.) + +LOUIS XVIII. (LOUIS LE DÉSIRÉ) (1755–1824). Louis-Stanislas-Xavier, comte de Provence, third son of the dauphin Louis, son of Louis XV., and of Maria Josepha of Saxony, was born at Versailles on the 17th of November 1755. His education was supervised by the devout duc de la Vauguyon, but his own taste was for the writings of Voltaire and the encyclopaedists. On the 14th of May 1771 took place his marriage with Louise-Marie-Joséphine of Savoy, by whom he had no children. His position at court was uncomfortable, for though ambitious and conscious of possessing greater abilities than his brother (Louis XVI.), his scope for action was restricted; he consequently devoted his energies largely to intrigue, especially against Marie Antoinette, whom he hated.¹ During the long absence of heirs to Louis XVI., "Monsieur," as heir to the throne, courted popularity and took an active part in politics, but the birth of a dauphin (1781) was a blow to his ambitions.² He opposed the revival of the parlements, wrote a number of political pamphlets,³ and at the Assembly of Notables presided, like the other princes of the blood, over a bureau, to which was given the name of the Comité des sages; he also advocated the double representation of the tiers. At the same time he cultivated literature, entertaining poets and writers both at the Luxembourg and at his château of Brunoy (see Dubois-Corneau, Le Comte de Provence à Brunoy, 1909), and gaining a reputation for wit by his verses and mots in the salon of the charming and witty comtesse de Balbi, one of Madame's ladies, who had become his mistress,⁴ and till 1793 exerted considerable influence over him. He did not emigrate after the taking of the Bastille, but, possibly from motives of ambition, remained in Paris. Mirabeau thought at one time of making him chief minister in his projected constitutional government (see Corr. de Mirabeau et La Marck, ed. Bacourt, i. 434, 436, 442), but was disappointed by his caution and timidity. The affaire Favras (Dec. 1789) aroused great feeling against Monsieur, who was believed by many to have conspired with Favras, only to abandon him (see Lafayette's Mems. and Corr. of Mirabeau). In June 1791, at the time of the + +¹See Arneth and Geffroy, Corr. de Marie-Thérèse avec le comte de Mercy-Argenteau, vol. i., "Mercy to Maria Theresa, June 22nd, 1771," also i. 261, ii. 186, 352, 393. Marie Antoinette says (ii. 393): " . . . à un caractère très faible, il joint une marche souterraine, et quelquefois très basse." + +²See his letters to Gustavus III. of Sweden in A. Geffroy, Gustave III et la cour de France, vol. ii. appendix. + +³Two pamphlets at least are ascribed to him: "Les Mannequins, comte ou histoire, comme l'on voudra" (against Turgot; anon., Paris, 1776) and "Description historique d'un monstre symbolique pris vivant sur les bords du lac Fagua, près de Santa-Fé, par les soins de Francisco Xaveiro de Neunris" (against Calonne; Paris, 1784) (A. Débidour in La Grande Encyclopédie). + +⁴It has frequently been alleged that his relations with Mme de Balbi, and indeed with women generally, were of a platonic nature. De Reiset (La Comtesse de Balbi, pp. 152-161) produces evidence to disprove this assertion. + +flight to Varennes, Monsieur also fled by a different route, and, in company with the comte d'Avaray⁶—who subsequently replaced Mme de Balbi as his confidant, and largely influenced his policy during the emigration—succeeded in reaching Brussels, where he joined the comte d'Artois and proceeded to Coblenz, which now became the headquarters of the emigration. + +Here, living in royal state, he put himself at the head of the counter-revolutionary movement, appointing ambassadors, soliciting the aid of the European sovereigns, and especially of Catherine II. of Russia. Out of touch with affairs in France and surrounded by violent anti-revolutionists, headed by Calonne and the comte d'Artois, he followed an entirely selfish policy, flouting the National Assembly (see his reply to the summons of the National Assembly, in Daudet, op. cit. i. 96), issuing uncompromising manifestoes (Sept. 1791, Aug. 1792, &c.), and obstructing in every way the representatives of the king and queen.⁶ After Valmy he had to retire to Hamm in Westphalia, where, on the death of Louis XVI., he proclaimed himself regent; from here he went south, with the idea of encouraging the royalist feeling in the south of France, and settled at Verona, where on the death of Louis XVII. (8th of June 1795) he took the title of Louis XVIII. At this time ended his liaison with Mme de Balbi, and the influence of d'Avaray reached its height. From this time onward his life is a record of constant wanderings, negotiations and conspiracies. In April 1796 he joined Condé's army on the German frontier, but was shortly requested to leave the country, and accepted the hospitality of the duke of Brunswick at Blanckenberg till 1797, when, this refuge being no longer open to him, the emperor Paul I. permitted him to settle at Mittau in Courland, where he stayed till 1801. All this time he was in close communication with the royalists in France, but was much embarrassed by the conflicting policy pursued by the comte d'Artois from England, and was largely at the mercy of corrupt and dishonest agents.⁷ At Mittau was realized his cherished plan of marrying Madame Royale, daughter of Louis XVI., to the duc d'Angoulême, elder son of the comte d'Artois. From Mittau, too, was sent his well-known letter to Bonaparte (1799) calling upon him to play the part of Monk, a proposal contemptuously refused (E. Daudet, Hist. de l'émigration, ii. 371, 436), though Louis in turn declined to accept a pension from Bonaparte, and later, in 1803, though his fortunes were at their lowest ebb, refused to abdicate at his suggestion and accept an indemnity. + +Suddenly expelled from Mittau in 1801 by the capricious Paul I., Louis made his way, in the depth of winter, to Warsaw, where he stayed for three years. All this time he was trying to convert France to the royalist cause, and had a "conseil royal" in Paris, founded at the end of 1799 by Royer-Collard, Montesquieu and Clermont-Gallerande, the actions of which were much impeded by the activity of the rival committee of the comte d'Artois (see E. Daudet, op. cit. ii., and Remâle, Bonaparte et les Bourbons, Paris, 1899), but after 1800, and still more after the failure of the royalist conspiracy of Cadoudal, Pichegru and Moreau, followed by the execution of the duc d'Enghien (March 1804), and the assumption by Napoleon of the title of emperor (May 1804), the royalist cause appeared quite hopeless. In September 1804 Louis met the comte d'Artois at Calmar in Sweden, and they issued a protest against Napoleon's action, but being warned that he must not return to Poland, he gained permission from Alexander I. again to retire to Mittau. After Tilsit, however (1807), he was again forced to depart, and took refuge in England, where he stayed first at Gosfield in Essex, and afterwards (1809 onwards) at Hartwell in Buckinghamshire. + +⁵Antoine-Louis-François de Bésiade, comte, afterwards duc, d'Avaray. In spite of his loyalty and devotion, the effect of his influence on Louis XVIII. may be gathered from a letter of J. de Maistre to Blacas, quoted by E. Daudet, Hist. de l'émigration, ii. II: "celui qui n'a pu dans aucun pays aborder aucun homme politique sans l'aliéner n'est pas fait pour les affaires." + +⁶See Klinckowström, Le Comte de Fersen et la cour de France. Fersen says (i. 7); "Monsieur ferait mieux seul, mais il est entièrement subjugé par l'autre" (i.e. the comte d'Artois, who was in turn under the influence of Calonne). See Daudet, op. cit. vol. i. + +⁷See E. Daudet, La Conjuration de Pichegru (Paris, 1901). + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg811_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg811_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..280c0926c8f465b3cf73e902a501d286f53a9b1f --- /dev/null +++ b/outputs/long_tiny_text/13_pg811_pg1_pg1_repeat1.md @@ -0,0 +1,31 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +“the right of issuing commissions in war and rebellion.” But he rightly adds that the military commander may permit the usual courts to continue their jurisdiction upon such subjects as he thinks proper. Legislative enactments have also sanctioned this special jurisdiction at various times, notably in 1798, 1799, 1801, and in 1803. These enactments lay down that exceptional powers may be exercised “whether the ordinary courts shall or shall not be open.” As an invariable rule an act of indemnity has been passed on the withdrawal of martial law, but only to protect any person in charge of the execution of martial law who has exceeded his powers in good faith. + +There has been much discussion as to whether, in districts where martial law has not been proclaimed, a person can be sent for trial from such district into a district where martial law was in operation. It is argued that if the ordinary courts were open and at work in the non-proclaimed district recourse should be had to them. The Privy Council in 1902 ( re Marais ) refused leave to appeal where the Supreme Court of Cape Colony had declined to issue a writ of Habeas Corpus in these circumstances. Mr Justice Blackburn in his charge in R. v. Eyre says, "I have come to the conclusion that, looking at what martial law was, the bringing of a person into the proclaimed district to be tried might, in a proper case, be justified." The learned judge admits that there should be a power of summary trial, observing all the substantials of justice, in order to stamp out an insurrection by speedy trial. + +Whilst martial law is the will of the commanders, and is only limited by the customs of war and the discretion of those who administer it, still, as far as practicable, the procedure of military law is followed, and a military court is held on the same lines as a court-martial. Charges are simply framed without technicalities. The prisoner is present, the evidence of prosecution and prisoner is taken on oath, the proceedings are recorded, and the sentence of the court must be confirmed according to the rules of the Army Act. Sentences of death and penal servitude must be referred to headquarters for confirmation. In the South African War (1899-1902) these limits of procedure were observed, and when possible will always be. + +Entering more into detail, the term martial law has been employed in several senses:—(1) As applied to the military + +Different forces of the crown, apart from the military law Applications under the old Mutiny Acts, and the present annual of Martial Army Acts. (2) As applied to the enemy. (3) Law. + +As applied to rebels. (4) As applied to civilian subjects who are not in rebellion, but in a district where the ordinary course of civil life cannot be maintained owing to war or rebellion. + +1. In regard to the military forces of the crown, the superseding of justice as administered under the Army Act could only occur in a time of great need; e.g. mutiny of five or six regiments in the field, with no time to take the opinion of any executive authority. The officer in command would then be bound to take measures for the purpose of suppressing such mutiny, even to putting soldiers to death if necessary. It would be a case where necessity forced immediate action. + +2. Martial law as applied to the enemy or the population of the enemy's country, is in the words of the duke of Wellington, "the will of the general of the army, though it must be administered in accordance with the customs of war." + +3, 4. But it is as affecting the subjects of the crown in rebellion that the subject of martial law really obtains its chief importance; and it is in this sense that the term is generally used; i.e. the suspension of ordinary law and the temporary government of the country, or parts of it, or all of it, by military tribunals. It has often been laid down that martial law in this sense is unknown to the law of England. A. V. Dicey, for instance, restricts martial law to only another expression for "the common right of the crown and its servants to repel force by force, in the case of invasion, insurrection, or riot, or generally of any violent resistance." But more than this is understood by the term martial law. + +When the proposition was laid down that martial law in this sense is unknown to the law of England, it is to be remembered that fortunately in England there never had been a state at all similar to that prevailing in Cape Colony in 1900-1902, and it may perhaps be questioned whether the statement would have been made with such certainty if similar events had been present to the writers' minds. + +In the charge delivered by Mr Justice Blackburn in the Jamaica case the law as affecting the general question of martial law is well set out. + +"By the laws of this country," said Mr Justice Blackburn, "beginning at Magna Carta and getting more and more established, down to the time of the Revolution, when it was finally and completely established, the general rule was that a subject was not to be tried or punished except by due course of law; all crimes are to be determined by juries subject to the guidance of the judge; that is the general rule, and is established law. But from the earliest times there was this also which was the law, and is the law still, that when there was a foreign invasion or an insurrection, it was the duty of every good subject, in obedience to the officers and magistrates, to resist the rebels, . . . in such a case as that of insurrection prevailing so far that the courts of law cannot sit, there must really be anarchy unless there is some power to keep the people in order, . . . before that principle the crown claimed the prerogative to exercise summary proceedings by martial law . . . in time of war when this disturbance was going on, over others than the army. And further than that, the crown made this further claim against the insurgents, that whilst it existed, pending the insurrection and for a short time afterwards, the crown had . . . the power to proclaim martial law in the sense of using summary proceedings, to punish the insurgents and to check and stop the spread of the rebellion by summary proceedings against the insurgents, so as . . . to stamp out the rebellion. Now no doubt the extent to which the crown had power to do that has never been yet decided. Our law has been declared from time to time and has always been a practical science, that is, the judges have decided so much as was necessary for the particular case, and that has become part of the law. But it never has come to be decided what this precise power is." + +So far as the United Kingdom is concerned the need has never arisen. It has always been found possible to employ the ordinary courts directly the rebels have been defeated in the field and have been made prisoners or surrendered. "Fortunately in England only three occasions have arisen since the Revolution when the authority of the civil power was for a time, and then only partially, suspended," 1715, 1745 and 1780. Clode, Military Forces, ii. 163, says: "Upon the threat of invasion followed by rebellion in 1715, the first action of the government was to issue a proclamation authorizing all officers, civil and military, by force of arms (if necessary) to suppress the rebellion." This, therefore, would only seem to fall within the limited sense in which Dicey understands martial law to be legal, "the right of the crown and its servants to repel force by force." There was no attempt to bring persons before courts-martial who ought to be tried by the common law, and all the extraordinary acts of the crown were sanctioned by parliament. After the rebellion had been suppressed two statutes were passed, one for indemnity and the other for pardon. Before the revolution of 1745 similar action was adopted, a proclamation charging civil magistrates to do their utmost to prevent and suppress all riots, and acts of parliament suspending Habeas Corpus, providing for speedy trials; and of indemnity. In the Gordon Riots of 1780 a very similar course was pursued, and nothing was done which would not fall within Dicey's limitation. No prisoners were tried by martial law. + +In Ireland the ordinary law was suspended in 1798-1801 and in 1803. In 1798 an order in Council was issued to all general officers commanding H.M. forces to punish all persons acting in, aiding, or in any way assisting the rebellion, according to martial law, either by death or otherwise, as to them should seem expedient for the suppression and punishment of all rebels; but the order was communicated to the Irish houses of parliament, who expressed their approval by addresses to the viceroy. It was during the operation of this order that Wolfe Tone's case arose. Tone, a subject of the king, was captured on board a French man-of-war, and condemned to death by a court-martial. Curran, his counsel, applied to the king's + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/13_pg857_pg1_pg1_repeat1.md b/outputs/long_tiny_text/13_pg857_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1f2e6f276aa801ba2c83e1a4eab8a087ed66798b --- /dev/null +++ b/outputs/long_tiny_text/13_pg857_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +on the 1st of August, and Lady Masham then retired into private life. She died on the 6th of December 1734. + +Lady Masham was by no means the vulgar, ill-educated person she was represented to have been by her defeated rival, the duchess of Marlborough; her extant letters, showing not a little refinement of literary style, prove the reverse. Swift, with whom both she and her husband were intimate, describes Lady Masham as "a person of a plain sound understanding, of great truth and sincerity, without the least mixture of falsehood or disguise." The barony of Masham became extinct when Lady Masham's son, Samuel, the 2nd baron, died in June 1776. + +AUTHORITIES.—Gilbert Burnet, History of My Own Time , vol. vi. (2nd ed., 6 vols., Oxford, 1833); F. W. Wyon, History of Great Britain during the Reign of Queen Anne (2 vols., London, 1876); Earl Stanhope, History of England, comprising the Reign of Queen Anne until the Peace of Utrecht (London, 1870), and History of England from the Peace of Utrecht , vol. i. (7 vols., London, 1836–1854); Justin McCarthy, The Reign of Queen Anne (2 vols., London, 1902); An Account of the Conduct of the Dowager Duchess of Marlborough from first coming to Court to 1710 , edited by Nathaniel Hooke, with an anonymous reply entitled A Review of a Lale Treatise (London, 1842); Private Correspondence of Sarah, Duchess of Marlborough (2 vols., London, 1838); Letters of Sarah, Duchess of Marlborough (London, 1875); Mrs Arthur Colville, Duchess Sarah (London, 1904). Numerous references to Lady Masham will also be found scattered through Swift's Works (2nd ed., 19 vols., Edinburgh, 1824). + +(R. J. M.) + +MASHAM, SAMUEL CUNLIFFE LISTER, 1ST BARON (1815–1906), English inventor, born at Calverley Hall, near Bradford, on the 1st of January 1815, was the fourth son of Ellis Cunliffe (1774–1853), who successively took the names of Lister and Lister-Kay, and was the first member of parliament elected for Bradford after the Reform Act of 1832. It was at first proposed that he should take orders, but he preferred a business career and became a clerk at Liverpool. In 1838 he and his elder brother John started as worsted spinners and manufacturers in a new mill which their father built for them at Manningham, and about five years later he turned his attention to the problem of mechanical wool-combing, which, in spite of the efforts of E. Cartwright and numerous other inventors, still awaited a satisfactory solution. Two years of hard work spent in modifying and improving existing devices enabled him to produce a machine which worked well, and subsequently he consolidated his position by buying up rival patents, as well as by taking out additional ones of his own. His combing machines came into such demand that though they were made for only £200 apiece he was able to sell them for £1200, and the saving they effected in the cost of production not only brought about a reduction in the price of clothing, but in consequence of the increase in the sales created the necessity for new supplies of wool, and thus contributed to the development of Australian sheep-farming. In 1855 he was sent a sample of silk waste (the refuse left in reeling silk from the cocoons) and asked whether he could find a way of utilizing the fibre it contained. The task occupied his time for many years and brought him to the verge of bankruptcy, but at last he succeeded in perfecting silk-combing appliances which enabled him to make yarn that in one year sold for 23s. a pound, though produced from raw material costing only 6d. or 1s. a pound. Another important and lucrative invention in connexion with silk manufacture was his velvet loom for piled fabrics; and this, with the silk comb worked at his Manningham mill, yielded him an annual income of £200,000 for many years. But the business was seriously affected by the prohibitory duties imposed by America, and this was one reason why he was an early and determined critic of the British policy of free imports. In 1891 he was made a peer; he took his title from the little Yorkshire town of Masham, close to which is Swinton Park, purchased by him in 1888. In 1886 an Albert medal was awarded him for his inventions, which were mostly related to the textile industries, though he occasionally diverged to other subjects, such as an air-brake for railways. He was fond of outdoor sports, especially coursing and shooting, and was a keen patron of the fine arts. He died at Swinton + +Park on the 2nd of February 1906, and was succeeded in the title by his son. + +MASHONA, a Bantu-negro people, inhabitants of Mashonaland, Southern Rhodesia. The name Mashona has been derived from the contemptuous term Amashuina applied by the Matabele to the aborigines owing to the habit of the latter of taking refuge in the rocky hills with which the country abounds. Before the Matabele invasion about 1840 most of Southern Rhodesia was occupied by the Makalanga, the Makorikori and the Banyai, all closely related. Most of them became subject to the Matabele, but although they suffered severely from their attacks, the Mashona preserved a certain national unity. In 1890 the Mashona came under British protection (see RHODESIA). They are in general a peaceful, mild-mannered people, industrious and successful farmers, skilful potters, and weavers of bark cloth. + +The crafts, however, in which they excel are the smelting and forging of iron and wood-carving. They are also great hunters; and they are very fond of music, the most usual instrument being the "piano" with iron keys. Bows and arrows, assegais and axes are the native weapons, but all who can get them now use guns. Up to their conquest by the Matabele the Mashona worked the gold diggings which are scattered over their country; indeed as late as 1870 certain Mashona were still extracting gold from quartz ( Geog. Jour. April 1906). + +For the possible connexion of these people with the builders of the ruins at Zimbabwe and elsewhere, see RHODESIA: Archaeology; and ZIMBABWE. + +MASK (Fr. masque, apparently from med. Lat. mascus, masca, spectre, through Ital. maschera, Span. mascara), a covering for the face, taking various forms, used either as a protective screen or as a disguise. In the latter sense masks are mostly associated with the artificial faces worn by actors in dramatic representations, or assumed for exciting terror (e.g. in savage rites). The spelling "masque," representing the same word, is now in English used more specially for certain varieties of drama in which masks were originally worn (see DRAMA); so also "masquerade," particularly in the sense of a masked ball or an entertainment where the personages are disguised. Both "mask" and "masquerade" have naturally passed into figurative and technical meanings, the former especially for various senses of face and head (head of a fox, grotesque faces in sculpture), or as equivalent to "cloak" or "screen" (as in fortification or other military uses, fencing, &c.). And in the case of "death-masks" the term is employed for the portrait-casts, generally of plaster or metallic foil, taken from the face of a dead person (also similarly from the living), an ancient practice of considerable interest in art. An interesting collection made by Laurence Hutton (see his Portraits in Plaster , 1894), is at Princeton University in the United States. (For the historical mystery of the "man in the iron mask," see IRON MASK.) + +The ancient Greek and Roman masks worn by their actors—hollow figures of heads—had the double object of identifying the performers with the characters assumed, and of increasing the power of the voice by means of metallic mouthpieces. They were derived like the drama from the rural religious festivities, the wearing of mock faces or beards being a primitive custom, connected no doubt with many early types of folk-lore and religion. The use of the dramatic mask was evolved in the later theatre through the mimes and the Italian popular comedy into pantomime; and the masquerade similarly came from Italy, where the domino was introduced from Venice. The domino (originally apparently an ecclesiastical garment) was a loose cloak with a small half-mask worn at masquerades and costume-balls by persons not otherwise dressed in character; and the word is applied also to the person wearing it. + +See generally Altmann, Die Masken der Schauspieler (1875; new ed., 1896); and Dale, Masks, Labrets and Certain Aboriginal Customs (1885); also DRAMA. + +MASKELYNE, NEVIL (1732–1811), English astronomer, was born in London on the 6th of October 1732. The + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/14a_pg1_pg1_repeat1.md b/outputs/long_tiny_text/14a_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8df6209f00af34151cb5e39e0b595b5114ab3ce6 --- /dev/null +++ b/outputs/long_tiny_text/14a_pg1_pg1_repeat1.md @@ -0,0 +1,180 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Afro-Shirazi, also known as SHIRAZI, African tribe in Tanzania. + +·Tanzanian tribal lineage 17:1030h + +Afro-Shirazi Party, dominant political party (founded 1957) of the island of Zanzibar in Tanzania. + +·Tanzanian political structures 17:1033a + +AFSC: see American Friends Service Committee. + +AFT, or AMERICAN FEDERATION OF TEACHERS, U.S. trade union founded in 1916. + +·teacher associations and competition with + +NEA 18:16a + +Aftasids, Muslim Berber dynasty that ruled one of the party kingdoms (ta'ifahs) at Badajoz in western Spain (1022–94) in the period of disunity after the demise of the Umayyad caliphate of Córdoba. The Lower Frontier (modern central Portugal) had enjoyed a measure of autonomy after the death of the Umayyad caliph al-Hakam II (976), when it was ruled by his freed slave, Sābūr (976–1022). In 1022, at Sābūr's death, his minister 'Abd Allāh ibn Muhammad ibn Maslamah, who was known as Ibn al-Aftas, seized control of the kingdom and, assuming the title al-Mansūr (Made Victorious by God), ruled fairly peacefully until 1045. But trouble with the neighbouring 'Abbādids of Seville, which had begun at the end of al-Mansūr's rule, consumed the energies of his son Muhammad al-Muzaffar (reigned 1045–60). Constant warfare weakened Badajoz sufficiently to allow the Christian King Ferdinand I of Castile and León to extort tribute from al-Muzaffar and then to capture the frontier garrisons of Viseu and Lamego (1057). Ferdinand also took Coimbra and the surrounding area as far north as the Douro River (1063), in present Portugal. 'Umar al-Mutawakkil (reigned 1068–94), was also forced to pay tribute to Alfonso VI of Castile and León; and he made an unsuccessful attempt to annex Toledo, which was held by a rival Muslim dynasty (1080). When Toledo was eventually taken by Alfonso in 1085, al-Mutawakkil and several other Muslim kings appealed to the Almoravids of North Africa for assistance. Almoravid armies defeated Alfonso at az-Zallāqah near Badajoz (Oct. 23, 1086), establishing a foothold in Spain. Hence, al-Mutawakkil tried to bargain for Alfonso VI's support, but Badajoz fell to the Almoravids in 1094, and al-Mutawakkil and two of his sons were executed. + +afterbrain, also called METENCEPHALON, the foresection of the third primary embryonic brain vesicle, or the set of structures derived from it. + +·brain vesicle derivatives, table 2 12:1028 + +afterburner, device for injecting fuel into the tailpipe of a jet engine; combustion of this fuel produces additional forward thrust. + +·jet thrust acceleration process 10:157f + +·military aircraft design 18:775c + +·turbojet engine design 1:375f + +afterdance, German NACHTANZ, in European late-medieval and Renaissance dance, the second and livelier of two dances customarily performed together (e.g., pavane and galliard; basse danse and saltarello). Its melody was often a variation in metre and tempo of the first dance melody. + +after-image, visual illusion in which retinal impressions persist after the removal of stimulus. The original impression persists briefly, then gives way to a reversed, or negative, image in which the brightness and colour of the original are reversed (light becomes dark; red becomes green; etc.). A common after-image is the spot of light one sees after a flashbulb has been fired. + +afterincrease, in physiology, the resumption of a reflex action following its interruption by an inhibitory stimulus; the renewed activity is more vigorous than that preceding the interruption. + +afterlife, a new or continued or transformed existence after death, belief in which has been found in virtually all cultures and civilizations. + +·animal, plant, and human souls 1:915h + +·Australian agnostic position 1:312g + +·Baltic life-death threshold 2:666d passim to 667c + +Buddhist doctrine of reincarnation 3:422f + +·Chinese concept of karman and purgatory 4:424d + +·sainthood and salvation in Mahāyāna 16:164e + +·Celtic religious beliefs 3:1070f + +·death rite provisions and beliefs 13:1051g + +·East African cosmology consequence 6:1013d + +·Egyptian expectations in 5th dynasty 6:467e + +·Egyptian myths, conceptions, and + +beliefs 6:504c passim to 506g + +·Elysium, Hades, Tartarus, and oblivion 8:409a + +·Etruscan nirvana concept 15:1061a + +·Finno-Ugric ancestor cult rituals 7:312d + +·Gnostic doctrine of marriage to angels 8:217d + +·Hindu doctrines of karman and + +liberation 8:889e + +·Hindu mythic account in Upaniads 8:929f + +·Hindu upaniṣadic beliefs 8:936h + +·human nature and death customs 5:533b + +·Inca realms of the dead 9:261e + +·Indo-European notions among Hittites 1:830d + +·Iranian doctrine of soul's reward 9:871e + +·James's study and conclusion 10:28f + +Judaeo-Christian beliefs + +·Christian eschatological concepts 4:507f + +·Egyptian-Judaic conceptual + +parallelism 12:919h + +·eschatological neglect in Judaism 6:961g + +·Jewish doctrines and speculation 10:289d + +·Jewish soteriological development 16:203e + +·Pharisee and Sadducee beliefs 10:310h + +·Universalist thought in early Church 18:860c + +·kamihood and sainthood in Shinto 16:164c + +·Mesopotamian myth of man's divinity 11:1004f + +·monastic liberation of self 12:337b + +·Near Eastern comparative beliefs 12:917g + +·Norse concepts of Valhalla and + +Nifheim 8:39d + +·philosophical arguments and problems 15:602c + +·prehistoric death rites and cults 14:985c + +·primitive religion's relation to dead 14:1042d + +·sacramental death rite beliefs 16:115f + +·Scythian and Sarmatian beliefs 9:869d passim to 870a + +·Slavic beliefs about grave reopening 16:876a + +·Southeast American Indian beliefs 17:221f + +·spiritualists' universalist conceptions 17:512e + +·Zoroastrian echoes of Indian beliefs 19:1174b + +Afternoon Men (1931), a novel by Anthony Powell. + +·literary style and theme 10:1222d + +Afternoon of a Faun, The, translation of L'APRÈS-MIDI D'UN FAUNE, one-act ballet to Debussy's symphonic poem Prélude à l'après-midi d'un faune first performed in 1912 with choreography and book by V. Nijinsky, who also danced the role of the Faun. It is also the title of a one-act ballet by Jerome Robbins, also to Debussy's music, first performed in New York City in 1953. + +L'Après-midi d'un faune was the title of a masterly poem by the French symbolist poet Stéphane Mallarmé, evoking the ideal essence of fleeting phenomena. It inspired Debussy to write his Prélude. + +·Debussy's Prélude theme inspiration 11:387g + +afterripening, or DORMANCY, a suspension of growth of the embryo during ripening of the seed. It results at least in part from rapid and extensive water loss because of the conversion of soluble nutrients to their stored forms. This interruption of growth, or the lack of it in the seeds of many tropical plants, may be an adaptation to seasonal and climatic changes. Afterripening provides for germination at the most favourable time, when conditions of moisture, temperature, and day length are most conducive to plant growth. See also germination. + +·seed and fruit development 16:486c + +·seed dormancy and germination 16:486h + +·survival value 5:960e + +aftershock, one of a series of small shocks immediately following a large earthquake; these may continue for days or even months. Aftershocks may occur at some distance from the epicentre (point on the surface just above the earthquake's focus, or seat) of the major shock and are usually directly related to the size or force of that shock. They may represent elastic recovery and readjustment to new conditions of stress after the main movement on a fault. + +After Strange Gods, in full AFTER STRANGE GODS—A PRIMER OF MODERN HERESY (1934), a book by T.S. Eliot. + +·essay use in societal redefinition 10:1078e + +Aftonbladet, Swedish newspaper, founded in 1830. + +·newspaper publishing history 15:240b + +Aftonian Interglacial Stage, major division of Pleistocene deposits and time in North America (the Pleistocene Epoch began about 2,500,000 years ago and ended about 10,000 years ago). The Aftonian Interglacial, a time of relatively moderate climatic conditions, followed the Nebraskan Glacial Stage and preceded the Kansan Glacial Stage, both times of widespread continental glaciation and relative cold. The Aftonian was named for deposits studied in the region of Afton Junction, Iowa. The Aftonian deposits consist of ancient soil profiles that may also include peat and windblown deposits. Elsewhere, Aftonian deposits consist of sand and gravel. + +Study of fossil invertebrates in some regions indicates that the Aftonian climate was warmer and drier than that of today. The end of the Aftonian was apparently a time of great difficulty for many mammalian forms; numerous genera became extinct. It is difficult to pin-point the causes, but deteriorating climatic conditions as well as the introduction of new, competing forms may have been responsible. The Aftonian is thought to be equivalent to the Günz-Mindel Interglacial Stage of the European Pleistocene chronology. + +aftosa: see foot and mouth disease. + +‘Afula, largest city of the Plain of Esdraelon or Valley of Jezreel (Hebrew ‘Emeq Yizre’el), northern Israel. Named for the Arab village of Fulah, formerly at that site, it is sometimes called ‘Ir Yizre’el (City of Jezreel). Founded in 1925 on lands acquired by the American Zion Commonwealth, a land-development organization, it was the first planned urban settlement of Jewish Palestine. The city is situated at the junction of two main roads leading to Galilee and the north. One is the coastal road from Tel Aviv-Yafo; the other is the hill road from Jerusalem via Nābulus and Janin. The latter route is largely in Israeli-occupied Jordanian territory. Afula was also a station on the former narrow-gauge branch of the Hejaz Railway, which ran through the plain; it has been inactive and largely dismantled since World War II. + +At its foundation, most of the city's natural hinterland was occupied by collective or cooperative settlements. These were independent of 'Afula economically and socially, and most of them rejected urban society ideologically. As a result, the development of 'Afula as a quasi-metropolitan centre was hindered. Only after 1948 did the population begin to grow, due to the settlement of large numbers of Jewish immigrants. A new section, 'Afula 'Illit (Upper 'Afula), has been built on the slopes of Giv'at ha-More, about 5 mi (8 km) from the old central business district. + +‘Afula has a large sugar-refining plant, textile mills, and a nylon-stocking factory. The Plain of Esdraelon's large regional hospital, with nursing school, is there, as are a teacher's college and numerous government offices. Pop. (1970 est.) 16,900. +32°36' N, 35°17' E + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/14b_pg1_pg1_repeat1.md b/outputs/long_tiny_text/14b_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5195310cf6664ce81d9ce44f4fc5220e1efb37fa --- /dev/null +++ b/outputs/long_tiny_text/14b_pg1_pg1_repeat1.md @@ -0,0 +1,88 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +the French government, he was one of the negotiators of the Treaty of Blois (1504) with the emperor Maximilian I, and of the League of Cambrai against Venice. His death occurred on his return from another venture into Italy with Louis XII. + +·papal election candidacy 6:1083e + +Amboise, Jacques (Joseph) d': see d'Amboise, Jacques (Joseph). + +Amboise, Peace of (1563), French compromise whereby liberty of conscience was granted to the Huguenots, but the celebration of religious services was confined to the households of the nobility and a limited number of towns. + +·provisions for limited Huguenot + +freedom 7:630a + +Ambon, formerly AMBOINA, or AMBOYNA, island in Maluku Tengah (Central Moluccas) district of Maluku province, Indonesia, 7 mi (11 km) off the southwestern coast of the island of Ceram (Seram). Ambon's 294 sq mi (761 sq km) are generally hilly, with Mt. Salhatu rising to 3,405 ft (1,038 m). Subject to earthquakes, it has no active volcanoes but some hot springs and hot-gas vents, or solfataras. It has a tropical climate with an abundant rainfall. The hard and knotty Ambon wood, of great value for ornamental woodwork, is obtained from Ceram. There are few mammals indigenous to Ambon, but birds include a racquet-tailed kingfisher, a crimson lory, and a vivid crimson brush-tongued parrot. Many varieties of fish live in Teluk (bay) Ambon, whose eastern end contains some marine gardens. + +Ambon's clove trade first attracted the Portuguese, who named the island and founded a settlement in 1521. The Dutch captured the Portuguese fort in 1605, took over the spice trade, and in 1623 destroyed a British settlement in the Amboina Massacre (q.v.). The British took it in 1796, and after it had exchanged hands twice between the British and Dutch it was restored finally to the latter in 1814. An important naval base, Ambon was occupied by Japan during World War II. In 1950, after Indonesian independence, the Ambonese—many of whom had been educated in Christian schools and served in the Dutch administration and army—found their new social and economic position precarious, seceded from Indonesia, and proclaimed an independent South Moluccan Republic. The movement was suppressed by military action, though guerrilla warfare continued in Ceram, and many Ambonese fled to The Netherlands. The port town of Ambon, on Laitimor Peninsula on the eastern side of the bay, is about 8 mi from the harbour's outer entrance. The town has many houses and structures of stone and wide, often tree-lined, streets; Ft. Victoria, built in the early 17th century and later restored; a church dating from the earliest settlement; and a hospital. Barracks and a number of government buildings existed until many were destroyed in World War II. + +The Ambonese are mainly Melanesian, commonly with dark skin, curly to frizzy hair, flat noses, and thick lips; they also live in the Uliasers and on the nearby Ceram coast. Generally the Muslims live in the north and the Christians, in the majority, the south. The language is a lingua franca: Malay with many Portuguese and Dutch words. + +Agricultural production, generally insignificant, includes rice, maize (corn), coffee, root crops, sago, and cloves. Copra, sugar, and fish are exported. Palm wine is made. Ambon's port is the chief centre for shipment of produce and for distribution of imports. The island has adequate local roads, a government radio station, a telephone system, and Patimura airport (on the west side of the harbour). Pop. (1971 prelim.) island, 114,400; town, 76,033. + +3°43' S, 128°12' E + +·map, Indonesia 9:461 + +Amborellaceae, family of flowering plants in the order Laurales. + +·vascular system, floral structure, and classification 10:709e passim to 711f + +Amboseli, Lake, small lake on the border between Kenya and Tanzania. The Masai Amboseli Game Reserve and Kilimanjaro are to the east and southeast. + +2°37' S, 37°08' E + +·map, Kenya 10:424 + +·map, Tanzania 17:1026 + +Amboyna (Indonesia): see Ambon. + +Ambra, love poem by Lorenzo de' Medici. +·Santayana's translation 16:231d + +Ambracia (Greece): see Arta. + +Ambridge, borough, Beaver County, western Pennsylvania, U.S., on the Ohio River. Within its boundaries is the former village of Economy (1825–1906) established by the communal Harmony Society, led by George Rapp. The Harmonists (Rappites) were religious immigrants from Württemberg, Germany, who had previously settled at Harmony, Pa., and New Harmony, Ind. The community prospered for about 50 years but declined because of the practice of celibacy and the lack of converts. In 1901 the American Bridge Company purchased 2,500 ac (1,012 ha) and established a town. It was incorporated as a borough in 1905 and renamed Ambridge in 1906. The state of Pennsylvania purchased (1919) many of the original Rappite buildings, which have been restored as a historical village. + +In addition to the bridge works, one of the world's largest, manufactures include wrought iron, pipe, electrical equipment, and building materials. Pop. (1970) 11,324. + +Ambrim, also spelled AMBRYM, island in the New Hebrides, southwest Pacific Ocean. It has an area of 257 sq mi (665 sq km) and is known for its two active volcanoes: Mt. Marum, 4,380 ft (1,335 m), which last erupted in 1913; and Mt. Benbow, 3,720 ft, which had major eruptions in 1929, 1946, and 1950. The last was serious enough to warrant the evacuation of several hundred persons for resettlement on Efate. The island produces copra. Pop. (1972 est.) 4,800. 16°15' S, 168°10' E + +Ambrogio, Sant', basilica in Milan that is an outstanding example of Lombard Romanesque architecture. Portions date from the 9th and 10th centuries, the rebuilt vaulted nave and aisles date from 1128, the atrium from c. 1050, and the narthex from 1095–96. Donato Bramante designed parts of the basilica and its chapel between 1492 and 1497. + +Ambroise d'Évreux (poet): see Ambrose. + +Ambros, August Wilhelm (b. Nov. 17, 1816, Vysoké Mýto, near Prague—d. June 28, 1876, Vienna), musicologist, author of a comprehensive history of music. He studied law, entered the civil service in 1840, and became public prosecutor in Prague in 1850. A keen, well-trained musician and composer of a Czech opera, Bretislaw a Jitka, he also established himself as a brilliant writer on music. His pamphlet Über die Grenzen der Poesie und Musik (1856) contributed to a heated aesthetic controversy. In 1869 he became professor of music at Prague and, in 1872, of music history at Vienna. His Geschichte der Musik, incomplete at his death, covered antiquity, the Middle Ages, and the Renaissance. Scholars completed the work from his notes. + +Ambrose, Saint 1:657 (b. c. AD 339, Augusta Treverorum, modern Trier, W.Ger.—d. 397, Milan), bishop of Milan, biblical critic, and initiator of ideas that provided a model for medieval conceptions of church-state relations. + +Abstract of text biography. After serving as governor of Aemilia-Liguria (c. 370–374), Ambrose became bishop of Milan (374) by popular acclamation. He secured the rejection + +of an appeal for tolerance by pagan Roman senators (384), refused to surrender a church to Arian heretics (385–386), rebuked the emperor Theodosius (388), and imposed a public penance (390) on the Emperor for a massacre of Thessalonian citizens. His literary works have been acclaimed as masterpieces of Latin eloquence, and his musical accomplishments are remembered in his hymns. Ambrose is also remembered as the teacher who converted and baptized St. Augustine of Hippo, the great Christian theologian, and as a model bishop who viewed the church as rising above the ruins of the Roman Empire. + +REFERENCES in other text articles: + +·Augustine's conversion to Christianity 2:365d +·church and state under Theodosius 4:540e +·codification of Milanese chant 12:704h +·Stoic influence on Christianity 17:700a +·Theodosius and church-state + +controversy 18:273b + +·theological stance and hymnody 13:1085f + +Ambrose, or AMBROISE D'ÉVREUX (fl. c. 1190), Norman poet and chronicler, who accompanied Richard I of England as a minstrel on the Third Crusade. Nothing more is known of him than that he was probably a native of Évreux and was a noncombatant making the pilgrimage to Jerusalem. His account of the crusade is preserved in the Estoire de la guerre sainte ("History of the Holy War"), a poem of over 12,000 lines extant in an Anglo-Norman manuscript; but the Estoire is only an adaptation of Ambrose's work. The original poem was used by Richard, a canon of Holy Trinity, London, as the source for his Itinerarium Regis Ricardi ("Concerning the Expedition of King Richard"). The Estoire has not much literary merit, but it is a valuable historical source. + +Ambrose, original name ANDREY STEPANOVICH ZERTIS-KAMENSKY (1708–71), archbishop of Moscow (1768–71) who supported the Enlightenment in the Russian hierarchy, rousing the church to fight poverty and doing valuable work for church restoration in Moscow. During a plague in 1771 people crowded around a miraculous icon, and Ambrose removed it to prevent spread of infection; he was thereupon murdered by an enraged mob. + +Ambrose (1812–91), Russian religious leader. startsy influence on Russian society 6:159d + +Ambrose of Camaldoli, Italian AMBROGIO TRAVERSARI (b. Sept. 16, 1386, Portico, Italy—d. Oct. 20, 1439, Florence), Humanist, ecclesiastic, and patristic translator who helped effect the brief reunion of the Eastern and Western churches in the 15th century. He entered the Camaldolese Order in 1400 at Florence, where, over a period of 30 years, he mastered Latin and particularly Greek, which enabled him to translate Greek patristic works into Latin, including those of SS. Athanasius the Great of Alexandria, Basil the Great of Caesarea, and John Chrysostom of Constantinople. His reputation in Humanist circles won him the patronage of Cosimo de' Medici. + +Pope Eugenius IV appointed him minister general of the Camaldolese Order in 1431 and papal emissary to the Council of Basel in 1435. He served a prime role at the Council of Ferrara-Florence when, in 1438, as papal representative, he received at the council the Byzantine emperor John VIII and Patriarch Joseph of Constantinople. His expertise in Greek and Eastern theology made him a chief negotiator for the decree of union between the Latin and Greek churches promulgated shortly before his death. Although never formally beatified, he is commemorated at Florence and by the Camaldolese on November 20. + +ambrosia and nectar, in Greek mythology, sometimes the food, sometimes the drink, of + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/14c_pg1_pg1_repeat1.md b/outputs/long_tiny_text/14c_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2f839966fd9f1c1f1c26e7d176661853af831dbf --- /dev/null +++ b/outputs/long_tiny_text/14c_pg1_pg1_repeat1.md @@ -0,0 +1,93 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Republic, with an area of 10,450 sq mi (27,100 sq km), chiefly in the basins of the upper Vorskla, Donets, and Oskol rivers. The oblast, formed in 1954 and centred on Belgorod city, lies in a forest-steppe on rich soils. The natural vegetation of deciduous forest and feather-grass steppe, almost wholly cleared for agriculture since intensive settlement began in the 17th century, survives only as occasional oak groves along the rivers. Agriculture is highly developed, and the population is predominantly rural. Grains—wheat, barley, millet, and corn (maize)—are the main crops, with sugar beet in the west and sunflowers in the east. There are numerous orchards. Large iron deposits were opened up in the 1950s and are now exploited on a considerable scale at Gubkin, Lebedi, and Yakovlevo, much by open-pit mining. Pop. (1970 prelim.) 1,261,000. + +Belgorod, city and administrative centre of Belgorod oblast (region), western Russian Soviet Federated Socialist Republic, on the upper Donets River where it is crossed by the Moscow-Kharkov and Sumy-Donets Basin railways. Founded in 1593 as a fortress, it became the key stronghold in the elaborate Belgorod defensive line set up in 1635-58 to protect Russia's southern frontier against Tatar attack. It maintained its military and administrative significance until the late 18th century. Modern Belgorod has a range of light engineering, building materials (chalk and slate), and food-processing industries, as well as a teacher-training institute. Pop. (1970) 151,000. + +50°36' N, 36°35' E + +· map, Soviet Union 17:322 + +Belgorod-Dnestrovsky, town, in Odessa oblast (administrative region), Ukrainian Soviet Socialist Republic, on the southwestern shore of the broad, shallow Dnestr Estuary. In the 6th century bc, Greeks from Miletus established the colony of Tyras on the site. It later came under the Scythians, and was settled by Slavs in early Kievan times (9th century). After the fall of Kiev to the Tatars, Belgorod became a republican city-state under Moldavian princes, and the Genoese established their factory of Mauro Castro there. Stormed by the Turks in 1484, it remained Turkish under the name Akkerman until 1812, when it was ceded to Russia. From 1918 to 1940 it was included in Romania with the name Cetatea Albă; its Kievan name was restored in 1944. The modern town is a minor regional centre with light industries, notably fish canning. Pop. (1970) 33,000. +46°12' N, 30°20' E + +Belgrade 2:825, Serbo-Croatian BEOGRAD, (White Fortress), capital city of Yugoslavia and of Serbia, situated at the confluence of the Danube and Sava rivers. Pop. (1971) city, 741,613; metropolitan area, 1,204,271. + +The text article contains a summary of Belgrade's 2,000-year history and a description of the contemporary city. + +44°50' N, 20°30' E + +REFERENCES in other text articles: + +·Eugene of Savoy's military conquest 6:1022h +·map, Yugoslavia 19:1100 + +·Ottoman territorial concessions 13:783e + +Belgrade, Treaties of (September 1739), two peace settlements achieved by the Ottoman Empire that ended a four-year war with Russia and a two-year war with Austria. + +Disputes arising from ill-defined frontiers between the Ukraine and the Ottoman-dominated Crimean Tatars provided the pretext in 1735 for a new Russian attempt to establish itself on the northern Black Sea. Austria entered the war as Russia's ally in 1737. Because of military failures, however, Austria made a separate peace in September 1739, ceding northern Serbia (with Belgrade) and Little Walachia (in southern Romania) to the Otto- + +mans and thus renouncing the strong position in the Balkans it had obtained under the Treaty of Passarowitz (1718). With Austria's defection, the militarily successful Russians had to make a disappointing peace that same month: Azov, which they had captured, was to be demilitarized, Russia was to have no warships on the Sea of Azov or the Black Sea, and it was to depend entirely on Ottoman shipping for its commerce on the Black Sea. + +The treaties, mediated and guaranteed by France, provided relatively stable conditions until 1768. + +Belgrano, northwestern residential section of Buenos Aires, Argentina. + +·architectural style 3:448d + +Belgrano, Manuel (b. June 3, 1770, Buenos Aires—d. June 20, 1820, Buenos Aires), military leader in the Argentine war for independence. After studying law in Spain, Belgrano was appointed secretary of the Buenos Aires official merchants' guild (1794), a position in which he advocated liberal ideas, particularly in education and economic reform. He received his first military experience during the unsuccessful British invasion of the Viceroyalty of Rio de la Plata in 1806-07. When Rio de la Plata broke with Spain in 1810, Belgrano became a member of the junta that tried to maintain its integrity. After outlying portions were lost, Belgrano was sent with a small army to bring what is now Paraguay under the authority of the junta but was unsuccessful. He later defeated pro-Spanish forces at Tucumán and Salta in the Argentine northwest, only to be defeated in Upper Peru (now Bolivia) in 1813. He was superseded in 1814 by José de San Martín as commander of the army. + +Belgrano, like many other leaders of the South American independence movement, favoured establishment of a monarchical type of government. To find a ruler, he went to Europe with Bernardino Rivadavia, who later became the first president of the Argentine Republic. The European mission was unsuccessful. + +·Paraguayan independence resistance 13:990c + +Belgrano Formation: see Pampean Group. + +Belial, a name used in the Old Testament, generally as an epithet for an evil or subversive person. In later Jewish apocryphal literature it became synonymous with Satan. +·Jewish dualistic Iranian elements 4:479h + +Bel-ibni, 8th-century-bc king of Babylonia. + +·Assyrian domination of Babylonia 11:985g + +Belice (country, South America): see British Honduras (Belize). + +Belice City (British Honduras): see Belize City. + +Belidor, Bernard Forest de (b. 1698, Catalonia, Spain—d. Sept. 8, 1761, Paris), military and civil engineer and author of a classic work on hydraulics. After serving in the French Army at an early age, he developed an interest in science and worked on the measurement of an arc of the Earth. The study of ballistics also attracted him, and he became professor of artillery at the French military school at La Fère and eventually rose to become inspector of artillery. He wrote several notable books on engineering, artillery, ballistics, and fortifications, but his fame rests primarily on Architecture Hydraulique, in four volumes (1737-53), covering engineering mechanics, mills and waterwheels, pumps, harbours, and sea works. + +belief, a mental attitude of acceptance or assent toward a proposition without the full intellectual knowledge required to guarantee its truth. Believing is apparently an introspectional occurrence, either an intellectual judgment or, as the 18th-century Scottish Skeptic David Hume maintained, a special sort of feeling with overtones that differ from those of disbelief. Beliefs have been distinguished accord- + +ing to their degree of certainty: a surmise or suspicion, an opinion, or a conviction. Belief becomes knowledge only when the truth of a proposition becomes evident to the believer. Belief in someone or something is basically different from belief that a proposition is true. + +belief, the problem of, the critical difficulty associated with the discrepancy between the aesthetic value of a literary work and the religious, moral, or ethical doctrines that the work espouses. + +Questions that are raised concerning the problem of belief in literary works include such matters as whether an immoral or politically threatening doctrine of a literary work detracts from its aesthetic value; or whether aesthetic value and acceptance promote the adoption of socially damaging action. + +The first statement of this problem is Socrates' famous attack on poets in Plato's Republic. Socrates argues that Homer lies when he portrays the domestic squabbles of Zeus and Hera or when he attributes evil fortune to the malice of some god. Such behaviour is incompatible with the concept of superior beings, and poetry that is not true is worthless. Socrates also assumed that a poet who represented base and ignoble characters must be himself ignoble. + +This problem exists to the present day and is frequently a matter of concern of the New Critics who question the assumption that aesthetic value and doctrinaire position are inseparable and take the position that one need not believe in hell in order to be able to appreciate Dante's Inferno. + +belief theory of probability, a theory of probability as a degree of the notion of a belief. + +·probabilistic theory and method 11:668d + +Believers' Baptism, the practice, among some Protestant denominations, of baptizing adult believers rather than infants. + +·Anabaptists' belief in adult baptism 15:106f + +Belin, Édouard (b. March 5, 1876, Vesoul, Fr.—d. March 4, 1963, Territet, Switz.), French engineer who in 1907 made the first telephoto transmission, from Paris to Lyon to Bordeaux and back to Paris, using an apparatus of his own invention. The first transatlantic transmission was made in 1921 between Annapolis, Md., and Belin's laboratories at La Malmaison, Fr. His equipment was adopted in Britain in 1928. It was used almost exclusively by European news media during the 1930s and 1940s, when the term "Belino" came into general use for all kinds of picture transmission. + +Belinga, mine site, Ogoové-Ivindo région northeast Gabon, western Africa. Iron ore has been found in the vicinity and a railroad, which will connect Belinga to the port of Owendo on the coast, was under construction in the 1970s. Wood and other forest products are important to the economy. +1°06' N, 13°11' W + +·map, Gabon 7:820 + +·mining industrial development 7:820e + +Belinsky, Vissarion (Grigoryevich) (b. July 12 [June 30, old style], 1811, Sveaborg, Fin.—d. June 7 [May 26, O.S.], 1848, St. Petersburg, now Leningrad), eminent Russian literary critic, "father" of the Russian radical intelligentsia. Expelled from the University of Moscow (1832), he earned his living as a journalist. His first substantial critical articles, "Literary Dreams" (published in the newspaper Molva, 1834), expounded F.W.J. Schelling's view of national character, applying it to Russian culture, though Belinsky later embraced Hegel's philosophy of history. He obtained a permanent post (1839) with the journal Otechestvennye zapiski. By 1840 he was showing signs of revolt against orthodox Hegelianism. + +Some Soviet critics, taking his rare political utterances out of context, consider his almost + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/14d_pg1_pg1_repeat1.md b/outputs/long_tiny_text/14d_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8618e57ff7442c0dd2c7be2a1d5f5e24ba82dac9 --- /dev/null +++ b/outputs/long_tiny_text/14d_pg1_pg1_repeat1.md @@ -0,0 +1,127 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Banjosidae, family of grunts in the fish order Perciformes. + +·classification and general features 14:51h + +Banjul: see Bathurst. + +bank, marine, rocky or sandy submerged elevation of the sea floor with a summit less than 200 metres (650 feet) deep but not shallow enough to endanger navigation. Many banks are local prominences on continental or insular (island) shelves. Similar elevations with tops deeper than 200 metres are called oceanic plateaus. Banks close enough to the sea surface to be hazardous to shipping are called shoals. Some banks provide favourable conditions for marine life and are therefore important fishing grounds—i.e., the Grand Bank of the North Atlantic. + +·continental shelf origins and extent 5:115e + +Bank, The (1915), film written and directed by Charles Chaplin. + +·plot and technique 12:519d + +Banka (Indonesia): see Bangka. + +Bánk bán (1821), Hungarian tragedy by Jozsef Katona. + +·Hungarian 19th-century literature 10:1214c + +Bank Craps, also called LAS VEGAS CRAPS, dice game, the variant of Craps most played in Nevada gambling houses. A special table and layout are used and all bets are made against the house. A player signifies his bet by placing chips or cash on the appropriate part of the layout before any roll. It is invariably required that the dice be thrown over a string or wire stretched a few inches above the surface of the table or that they strike a wall of the table and bounce back. + +The shooter, or anyone wishing to bet that the shooter will win, places his bet "on the line" (in the area marked DOES PASS, LINE, or WIN on some layouts). Anyone betting against the shooter places his bet in the area marked DON'T PASS. Anyone wishing to bet on a special contingency, such as that craps (2, 3, or 12) will or will not be thrown on the next roll, places his bet in the appropriate space on the layout; such bets are called proposition bets. The house maintains a mathematical advantage on all bets of about 1.4 percent, higher on certain layouts and special bets. + +New York Craps is a version of Bank Craps popular in the eastern United States, the Bahama Islands, and England. The table and layout, called a double-end dealer, are slightly different from those used in Bank Craps. + +bank deposit, payment of a sum of money to a bank in return for the right to be able to be repaid by the bank. Bank deposits payable a specified number of days after deposit are called time deposits. Bank deposits that may be withdrawn without notice are called demand deposits. + +·money forms and supply expansion +mechanisms 12:352c + +Bankes, John (1589–1644), English Lord Chief Justice. + +·Ship Money case decision 3:242e + +Bankeveld, ridge of Transvaal state, South Africa. + +·Transvaal soil and rock formations 18:685c + +Bank for Foreign Trade, in Russian VNESH-TORGBANK, Soviet bank handling foreign exchange transactions. + +·banking history in Soviet Union 2:704g + +Bank for International Settlements, international bank established at Basel, Switz., in 1930, as the agency to handle the payment of reparations by Germany after World War I and as an institution for cooperation among the central banks of the various countries. It has come to serve as a centre for economic and monetary research and consultation and + +as a technical agency for the execution of certain specific agreements. The bank's capital, divided into 200,000 registered shares, was fixed at 1,500,000,000 gold francs, only 25 percent of which has been paid in. Subscription of the capital was originally guaranteed in equal parts by the central banks of Belgium, France, West Germany, Great Britain, and Italy and by two banking groups, one from Japan and one from the United States. All of the U.S. stock was sold in American markets, with most of it being bought by Europeans. The Japanese interest was repurchased by other central banks. + +Liquidation of the bank was recommended at the Bretton Woods (N.H.) Conference of 1944, when the International Monetary Fund and the International Bank for Reconstruction and Development were founded, but such a step was avoided. In 1947 the bank was appointed agent for the execution of the first intra-European compensation agreement initiated under the Marshall Plan, and in 1950 it became the agent for the Organization for European Economic Co-operation to serve the European Payments Union (q.v.). After the liquidation of the EPU at the end of 1958, the bank was appointed agent for its successor, the European Monetary Agreement, which was to provide a new multilateral system of settlements. Earlier, in 1954, the bank had been invited to undertake certain functions as depositary for the European Coal and Steel Community. + +Under its statutes the bank may carry out only operations that are in conformity with the monetary policy of the countries concerned. Its granting of credits and its purchases and sales of gold and foreign exchange have been on a short-term basis only. The bank showed a profit every year, except for 1945; dividend payments were suspended then but resumed in 1951. The bank is administered by a board of directors consisting of governors of central banks and other elected members. + +·European Payments Union + +establishment 7:33b + +bank holidays, in the United Kingdom, those days designated as holidays by the Bank Holidays Act of 1871 and a supplementary act of 1875 for all the banks in England, Wales, Northern Ireland, and Scotland. Though they are not statutory public holidays, their observance is no longer limited to banks. + +Before 1830 the Bank of England closed on approximately 40 saints' days and anniversaries, but in that year the number was reduced to 18 days. In 1834 they were further reduced to four: Good Friday, May 1, November 1, and Christmas Day. By the act of 1871, the following were constituted bank holidays in England, Wales, and Ireland: Easter Monday; Whitmonday, the first Monday of August; December 26 if a weekday; and, by the act of 1875, December 27 when December 26 falls on a Sunday (Boxing Day). The Bank Holiday (Ireland) Act of 1903 designated March 17, St. Patrick's Day (or, if on a Sunday, the following Monday) as a bank holiday for Ireland. In England, Wales, and Northern Ireland, Christmas Day and Good Friday are bank holidays under common law. + +In Scotland, New Year's Day, Christmas Day (or, if these days fall on Sunday, the following Mondays), Good Friday, the first Monday of May, and the first Monday of August are bank holidays. + +The act of 1871 also made it lawful for any day to be officially proclaimed a bank holiday in the United Kingdom. In the 1960s the government changed the Whitmonday holiday to the Late Spring Bank Holiday and the August Bank Holiday to the Summer Bank Holiday observed on the Mondays nearest May 31 and August 31. + +Bankia setacea, species of mollusk in the class Bivalvia. + +·coloration pigments and functions 4:918d + +Banking Act of 1933, U.S. act that created the Federal Deposit Insurance Corporation. +·business financing operations 7:299g + +Banking Act of 1935, U.S. act that significantly increased the centralization of control of banks in the Board of Governors of the Federal Reserve System. + +·minimum bank reserve requirements 2:711a + +bank note, certificate issued by a bank promising to pay the bearer a specified sum of money upon demand. + +·banking development in 17th century 2:700h +·money market control and fund + +supply 12:357b + +Bank of Canada, central bank of Canada, set up by an act of 1934; began operations in March, 1935. + +·monetary policy implementation 3:724e + +Bank of China, banking institution in Peking under the supervision of the People's Bank of China. + +·Peking banking institutions 14:8h + +Bank of England, the central bank of the United Kingdom. It acts as the note-issuing authority, as the government's banker, as banker to the commercial banks, as manager of the national debt, as the government's agent for operating exchange controls, as its agent for implementing monetary policies, and as adviser to the government on major monetary and currency issues. Although nationalized only in 1946, the bank has been operated during the greater part of its life since its founding in August 1694 on the principle that the national interest rather than profit-making should be its main consideration. +·central bank establishment in 1694 12:352f + +·foreign exchange affected by interest + +rates 7:25d passion to 27d + +·money market and bank rate control 12:359e +·national debt funding in 17th century 3:249c +·open-market operations 2:710c + +·Ricardo and economics of early 1800s 15:825c +·United Kingdom financial structure 18:879f + +Bank of Greece (1928), central bank of Greece, in Athens. + +·ownership and functions 8:320b + +Bank of Guyana, central bank of Guyana, in Georgetown. + +·establishment and function 8:510f + +Bank of Italy, central bank of Italy, important in economic policy making. +·economic policy making 9:1100f + +Bank of Japan, central bank of Japan. + +·establishment and government role 10:48c + +Bank of the United States (1791–1811; 1816–36), successive national banks chartered by the federal government to establish public credit and to provide a universally acceptable currency for the new nation. Chief advocate of the bank was Alexander Hamilton, first secretary of the treasury, who in 1789 was faced with the problem of redemption of the U.S. War of Independence debt of \$56,000,000 (more than one-fifth owed to foreign lenders). + +On Feb. 25, 1791, Congress agreed to charter the Bank of the United States, with authority to issue currency backed by gold and government bonds and to conduct the general business of a commercial bank. Located in Philadelphia, the bank was capitalized at \$10,000,000, of which 20 percent was subscribed by the government and the rest privately. With the bank's formation, U.S. credit was established abroad, the war debt was redeemed, and an increased supply of currency was put into circulation. + +The legality of the bank immediately became a political issue, with strict constructionists questioning its authorization in the Constitution. Out of this division grew the nation's earliest political parties; the bank's supporters became known as Federalists and its opponents as Anti-Federalists. Despite the success of the bank, its charter was not renewed in + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/14e_pg1_pg1_repeat1.md b/outputs/long_tiny_text/14e_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fff5207920e273d60740a5ca703aab44e293b1fc --- /dev/null +++ b/outputs/long_tiny_text/14e_pg1_pg1_repeat1.md @@ -0,0 +1,125 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +making plants. Tourism is of prime importance, for during the mild winter months (May to September) thousands flock to the town, which has become an exploration base for the Centre. They may also attend such celebrations as "Henley on the Todd" (a "boat race" on the dry riverbed in which the boats are carried by runners). Alice Springs, which was the capital of the short-lived Territory of Central Australia (1926-31), is a regional headquarters for the Royal Flying Doctor Service and the School of the Air (public education by radio). Its original telegraph station has been designated a national park. Pop. (1971 prelim.) 11,118. + +23°42' S, 133°53' E + +·map. Australian External Territories 2:433 + +·map, Australia 2:400 + +·temperature, vegetation, and services 13:243a passim to 244h + +·urban geographic location map 2:425 + +alicyclic compound, in chemistry, any of a large class of organic compounds in which three or more atoms of the element carbon are linked together in a ring. The bonds between pairs of adjacent atoms may all be of the type designated single bonds (involving two electrons), or some of them may be double or triple bonds (with four or six electrons, respectively); six-membered rings for which a system of alternating single and double bonds may be envisioned, however, belong to another important class (aromatic compounds; q.v.), distinguished from the alicyclic compounds by a characteristically different pattern of chemical reactivity. + +Those alicyclic compounds in which the ring contains three, four, or five carbon atoms are less stable than the compounds having larger rings, because the angles formed by adjacent covalent bonds are smaller than is necessary for maximum effectiveness. In the larger rings all the bond angles have the preferred value (about \(109.5^{\circ}\)); consequently, the atoms in the ring do not lie in one plane. Similar restrictions on the angles in double and triple bonds affect the stability of alicyclic compounds containing such bonds. + +·heterocycle comparative chemistry 8:832h + +alidade, an accessory instrument used in plane-table surveying. + +·components and use 17:830g + +alien, in national and international law, a foreign-born resident who is not a citizen by virtue of parentage or naturalization and who is still a citizen or subject of another country. In early times and in various "dark ages," the tendency was to look upon the alien as an enemy and to treat him as a criminal or outlaw. Such attitudes were ameliorated in the time of such civilizations as the Roman Empire, when the jus gentium, the Roman law that applied to both citizens and foreigners, tended to favour the idea that aliens had rights; humanity toward aliens was also fostered, in theory at least, by the Christian idea of the unity of mankind. The legal and ideological expression of humanity toward the alien, however, is generally a relatively modern development. + +As sovereign national states began to develop in modern times, founders of international law asserted that natural rights were vested in all persons, without regard to citizenship or alienage—rights of which they ought not to be deprived by civilized societies or their governments. There was no general agreement on the content or scope of these rights as they affected aliens, but the existence of some minimum standard of civilized treatment was asserted. The minimum standard, it was conceded, did not include the right of the alien to own realty or to engage in gainful professions. To meet this situation, states entered into treaties that provided that each of the contracting states would treat the nationals of the other state on an equal footing with its own nationals in the admission into trades and professions, owner- + +ship or possession of property, access to courts, enjoyment of liberty of conscience, and freedom of worship. Some treaties do not purport to extend to aliens, however, rights that are by municipal law reserved exclusively to nationals of the country; thus, municipal law, rather than conventional international law, is actually controlling. In particular, the desire of nations to protect citizens in their jobs, professions, and businesses against unemployment and competition is a strong force restricting the latitude of aliens. + +Common economic needs of nations, on the other hand, have had some liberalizing effects on the status of aliens. The treaty constituting the European Common Market, for instance, provides that citizens of member states shall be free to reside in any signatory country that offers them employment; wages and working conditions are to be the same for citizens and aliens. This treaty may in time serve as a model to raise the so-called minimum standards in the treatment of aliens. + +·Roman legal status 15:1055c + +Alien and Sedition Acts (1798), series of four laws passed by the U.S. Congress restricting aliens and curtailing civil liberties in an attempt to silence criticism of the Federalist Party. Following the republican revolution in France (1789), many conservative European governments passed repressive laws in fear of domestic subversion. In the U.S. the Federalist Party, at the height of its power in 1798, feared war with France and the possible electoral success of its political opponents, the Jeffersonian Republicans. + +The three alien laws, adopted in June and July, were aimed at French and Irish immigrants, who were mostly Jeffersonians. These laws raised the waiting period for naturalization from 5 to 14 years, permitted the detention of subjects of an enemy nation, and authorized the chief executive to expel any alien he considered dangerous. Though the last provision was never applied, it frightened many Frenchmen into leaving the country and threatened to grant arbitrary power to the president. + +The Sedition Act (July 14) outlawed the publishing of false or malicious writings against the government and the inciting of opposition to any act of Congress or the president. This law evoked strenuous opposition among Anti-Federalists, who termed it unconstitutional in violation of the First Amendment, and triggered such state denunciations as the Virginia and Kentucky resolutions (q.v.). Under the Sedition Act, 25 arrests were made, resulting in ten convictions; the extent of censorship was much greater than indicated by these figures, however. Enforcement ceased because many of the Sedition Act's victims became martyrs or heroes in the public eye. Congress refunded a number of the fines 40 years later. All the Alien and Sedition Acts either expired or were repealed between 1800 and 1802. + +·Clay's opposition and political effects 4:699a +·Jefferson's reaction 10:129f + +·Kentucky opposition and leadership 10:419f + +·newspaper publishing and censorship 15:239e + +·Republican political opposition 18:959g + +alienation 1:574, in general terms, the estrangement of a person or his affections. In philosophy, theology, psychology, and the social sciences, the term has been used variously but usually with emphasis on either personal powerlessness, meaninglessness, normlessness, cultural estrangement, social isolation, or self-estrangement. + +The text article covers the history of the term and its current definitions, as well as the causes, manifestations, and proposed remedies relating to the problems of alienation. + +REFERENCES in other text articles: + +·Buber's delineation of relationships 3:359e + +·bureaucracy and political processes 3:489c + +·Camus's theme of post-war isolation 3:711g + +·drug abuse effects and causes 5:1051c + +·Durkheim study of causes 5:1094d + +·Marx's adaptation of Hegelian concept 14:271a + +·mass society communications overload 15:42a +·millenialism as dissidence expression 12:203b +·minority groups in society 12:260h + +·mystical attitude origin and character 12:786a +·neighbourhood breakdown and crime 5:267d +·prison's effect on personality 14:1101d + +·psychoses as mental estrangements 15:173g + +·religious movement cause 18:698g + +·sectarian religion and church + +authority 15:606e + +·social movements psychological + +appeal 16:978e + +·subjectivity, love, and otherness 15:597f + +·totalitarianism cause theories 11:602g + +·youth violent expression 19:1097c + +RELATED ENTRIES in the Ready Reference and Index: + +alienation of labour: anomic: inner-directed and other-directed + +alienation effect, also called A-EFFECT, German VERFREMDUNGS-EFFEKT, or V-EFFEKT, idea central to the dramatic theory of German dramatist-director Bertolt Brecht. It involves the use of a variety of techniques all designed to "distance" the audience from the play and to jolt it into realizing that it is watching a theatrical performance; thus, the audience's degree of emotional identification with characters and events is strictly controlled, and it can more objectively and clearly perceive the "real" world reflected in the drama. + +·Brecht's anti-illusive techniques 18:232a +·epic theatre staging 17:551d + +alienation of labour, Marxian theory holding that the industrial labourer under capitalism is estranged from the products of his work. According to the theory, not only does the extreme and elaborate division of labour prevent the worker from identifying himself with the final product but capitalist exploitation also prevents him from possessing it. Class division and revolutionary sentiment are understood as expressions on the social level of the individual labourer's alienation and disaffection. Critics of the theory have argued, however, that the worker's loss of dignity is redeemed by the additional wealth and leisure won through the division of labour. The concept of alienation has given rise to an extensive philosophical, psychological, and sociological literature, both Marxist and non-Marxist. + +·critique of capitalist society 11:554f + +·economic and social analysis of + +labour 11:554d + +·theory of social organisms 11:552e + +Aliens Act (1705), measure passed by the English Parliament that prohibited all Scottish imports to England if the Scots would not accept the Hanoverian succession. + +Alienus, Aulis Caecina: see Caecina Alienus, Aulis. + +alif, first letter of the Arabic alphabet. It has no equivalent in English, but is often transcribed with the diacritic hamzah'. + +·Islamic symbolic and numerical value 9:951d + +Aligarh, administrative headquarters, Aligarh district, Uttar Pradesh state, northern India, southeast of Delhi. The town itself is usually called Koil or Kol; Aligarh is the name of a nearby fort. The town is an agricultural trade centre; the processing of agricultural products and manufacturing are also important. Aligarh Muslim University (1875) and its affiliated colleges are located there, as are a number of other degree colleges. Another old fort, the Dor fortress (1524), lies at the town's centre; now in ruins, its site is occupied by an 18th-century mosque. The town also contains the tombs of several Muslim saints. + +Aligarh district, 1,941 sq mi (5,027 sq km) in area, is a largely level region crossed by the Ganges Canal and several rivers. Wheat, bar- + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/15a_pg1_pg1_repeat1.md b/outputs/long_tiny_text/15a_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6dcc7999705fd7658d9fbb98547fa5461240c4a0 --- /dev/null +++ b/outputs/long_tiny_text/15a_pg1_pg1_repeat1.md @@ -0,0 +1,36 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +we call waking life may be only an unusual and persistent nightmare" and further stated that "I do not believe that I am now dreaming but I cannot prove I am not." Philosophers generally try to resolve the question by saying that so-called waking experience seems vivid and coherent. As French philosopher René Descartes (1596-1650) put it: "... memory can never connect our dreams one with the other or with the whole course of our lives as it unites events which happen to us while we are awake"; or, as Russell stated succinctly: "Certain uniformities are observed in waking life, while dreams seem quite erratic." + +Dreams in +various +cultures + +Members of many cultures have variously coped with this dilemma; for example, among the Eskimo of Hudson Bay and the Patani Malay people, it is believed that during sleep one's "soul" leaves his body to live in a special dreamworld. Believers often consider it dangerous to wake someone lest his "soul" be lost. On these grounds the Tajal people of Luzon, for example, severely punish for awakening a sleeping person. In other cultures, dream events are held to be identical with reality; thus a Macusi Indian of Guyana is reported to have become enraged at the European leader of an expedition when he dreamed that the leader had made him haul a canoe up dangerous cataracts. He awoke exhausted and could not be persuaded that the dream was not real. There is a tradition in Borneo that if a man dreams that his wife is an adulteress, her father must take her back. A Zulu man is said to have broken off a friendship after dreaming that the friend meant him harm. A Paraguayan Indian, reportedly having dreamed a missionary shot at him, attempted to kill the missionary. + +In other instances, dream events are believed to demand fulfillment. Jesuit priests in the 1700s reported that among Iroquois Indians it was obligatory to carry out dreams as soon as possible; one Indian was said to have dreamed that ten friends dove into a hole in the ice of a lake and came up through another. When told of the dream, the friends duly enacted their roles in it, but unfortunately, only nine of them succeeded. After dreaming of something valuable, Kurdish people were immediately expected to take it, by force if necessary. Among some natives of Kamchatka a man need only dream of a girl's favour for her to owe him her sexual favours. + +Such interpretations in which the dream is given a status of reality need not imply that the two are indistinguishable. In some instances, the dream may be differentiated from reality, but dreams are accorded a superior status to the banal activities of wakefulness. + +Dreams as a source of divination. There is an ancient belief that dreams predict the future; the Chester Beatty Papyrus is a record of Egyptian dream interpretations dating from the 12th dynasty (1991–1786 BC). In the Iliad, a character named Agamemnon is visited in dream by a messenger of the god Zeus to prescribe his future actions. From India, a document called the Atharvaveda, attributed to the 5th century BC, contains a chapter on dream omens. A Babylonian dream guide was discovered in the ruins of the city of Nineveh among tablets from the library of the emperor Ashurbanipal (668–627 BC). The Old Testament is rife with prophetic dreams, those of the pharaohs and of Joseph and Jacob being particularly striking. Among pre-Islamic peoples dream divination so heavily influenced daily life that the practice was formally forbidden by Muhammad (c. 570?–632), founder of the Muslim religion. + +Ancient and religious literatures express most confidence about so-called message dreams. Characteristically, a god or some other respected figure appears to the dreamer (typically a king, a hero, or a priest) in time of crisis and states a message. Such reports are found on ancient Sumerian and Egyptian monuments; frequent examples appear in the Old and New testaments. Joseph Smith (1805–1844), the founder of the Mormon religion, said that an angel had directed him to the location of buried golden tablets that described American Indians as descendants of the tribes of Israel. + +Not all dream prophecies are so readily accepted. In + +the epic Odyssey, for example, dreams are classed as false ("passing through the gate of Ivory") and as true ("passing the Gate of Horn"). Furthermore, prophetic meaning may be attributed to dream symbolism. In the Bible, Joseph interpreted sheaves of grain and the moon and stars as symbols of himself and of his brethren. In general, the social status of dream interpreters varies; in cultures for which dreams loom important, their interpretation frequently is a specialized occupation of such people as priests, elders, or medicine men. + +Perhaps the most famous dream interpretation book is that of the Greek geographer, Artemidorus (c. 2nd century AD) and is called Oneirocritica (from the Greek oneiros, "a dream"). Dream books remain widely available today. They continue to enjoy profitable sales in Europe, Asia, the Americas, Africa, and elsewhere among people who follow them in affairs of the heart, in gambling, and in matters of health and work. + +Dreams as curative. So-called prophetic dreams in the Middle-Eastern cultures of antiquity often were combined with other means of prophecy, such as animal sacrifice, and with efforts to heal the sick. In classical Greece, dreams became directly associated with healing; ailing people came to dream in oracular temples where priests and priestesses advised about the cures dreams were held to provide. Similar practices, known as dream incubation, are recorded for Babylon and Egypt. In a widespread cult, suffering petitioners came to at least 600 temples of the Greek god of medicine to perform rites or sacrifices in efforts to dream appropriately, sleeping in wait of the appearance of the god or his emissary to deliver a cure. Many stone monuments placed at the entrances of the temples survive to record dream cures. + +Dreams as extensions of the waking state. Even in early human history dreams also were interpreted as reflections of waking experiences and of emotional needs. Aristotle (384–322 BC), despite his contemporaries who practiced divination and incubation, in his work Parva naturalia attributed dreams to sensory impressions from "external objects ... pauses within the body ... eddies ... of sensory movement often remaining like they were when they first started, but often too broken into other forms by collision with obstacles." In anticipation of psychoanalyst Sigmund Freud (1859–1939), Aristotle wrote that sensory function is reduced in sleep, favouring the susceptibility of dreams to emotional subjective distortions. + +In spite of Aristotle's unusually modern views and even after a devastating attack by the Roman statesman Marcus Tullius Cicero (106–43 BC) on dream divination (De divinatione), views that dreams have supernatural attributes persisted vigorously until the 1850s and the classical work of French physician Alfred Maury, who studied more than 3,000 reported recollections of dreams. Maury concluded that dreams arose from external stimuli, instantaneously accompanying such impressions. He wrote that part of his bed once fell on the back of his neck and woke him, leaving the memory of dreaming that he had been brought before a French revolutionary tribunal, questioned, condemned, led to the scaffold, bound by the executioner and that the guillotine blade fell. + +The English poet Coleridge reported that he had written "Kubla Khan" as the result of creative thinking in a dream. Having fallen asleep while reading about that Mongol conqueror, he woke to write down a fully developed poem he seemed to have composed while dreaming. Novelist Robert Louis Stevenson said that much of his writing was developed by "little people" in his dreams, and specifically cited the story of Dr. Jekyll and Mr. Hyde in this context. A German chemist, F.A. Kekulé von Stradonitz, attributed his interpretation of the ring structure of the benzene molecule to his dream of a snake with a tail in its mouth. Otto Loewi, a German physiologist, attributed to a dream inspiration for an experiment with a frog's nerve that helped him win the Nobel Prize. In all of these cases the dreamers reported having + +Creative +dreaming + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/15b_pg1_pg1_repeat1.md b/outputs/long_tiny_text/15b_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e30e437eb321016a4311aea6fd7ae5b9d076bd90 --- /dev/null +++ b/outputs/long_tiny_text/15b_pg1_pg1_repeat1.md @@ -0,0 +1,37 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +similar function. In these highly social insects, in which different members of the society are structurally and behaviourally specialized to perform different tasks, dispersal to new areas and the founding of new colonies is the task of the winged forms. + +A third form of polymorphism exhibited by insects is life-history polymorphism as exhibited among butterflies, dragonflies, and wasps. In all of these insects the wingless larvae are the feeding phase and disperse little, whereas the adults are the dispersal phase and feed little. In fact, the adults of some insects, such as mayflies, do not feed at all, but disperse, mate, lay eggs, and die. + +There are exceptions to the statement that larval insects disperse little, which introduces a fourth kind of polymorphism, termed behavioural polymorphism. In a population of the larch budmoth (Zeiraphera griseana) in Switzerland, there are at least two types of larva that differ in structure and behaviour. One is intolerant to crowding; it disperses readily and is usually the first to appear on the principal food plant, larch trees. The other is tolerant to crowding and disperses little. The proportion of these two types in the population varies from time to time in accordance with the overall density. A balance of advantages and disadvantages allows the two forms to persist together without one replacing the other. + +As indicated by the above example, natural selection does not always favour the individuals that disperse the most. If the chances of dispersing and finding a new, suitable, and unexploited environment are very low, selection will act against the strong dispersers. Such seems to be the case in highly restricted and well-isolated environments such as oceanic islands and mountain tops. In these environments the number of flightless birds and insects is striking, and is much greater than in continental regions. Charles Darwin pointed out that the possession of large wings and well-developed powers of flight could be a disadvantage to animals on oceanic islands, particularly small ones, because an occasional strong wind might carry an already airborne animal away from the island and out to sea. The zoogeographer P.J. Darlington has emphasized that wings are also used in flight from predators, but predators are scarce or absent on these islands, so the need for dispersal powers within the island environment is not as great as within continental environments. + +Passive dispersal. Organisms are dispersed passively by three principal agents: wind, water, and other organisms. + +Dispersal by wind and by water. The capability of wind to transport organisms is well known, but the extent and the scale of such transportation is only now becoming clear. Microscopic organisms, such as viruses and protozoa, are readily carried by the wind, but even some of the smaller vertebrate animals such as frogs can be carried along on strong winds. Spiders, mites, and insects have been collected on airplane flights across the Pacific Ocean at distances up to 3,000 kilometres (1,900 miles) from land. Because of the method of capture, specimens are dead, so there is no means of distinguishing whether they were or were not living when they were collected. Nevertheless, in view of these remarkable results, it is no longer surprising that even the most isolated islands have an extensive insect fauna. There are, for example, close to 4,000 insect species native to the geographically rather remote Hawaiian Islands. It has been suggested that these species evolved from 250 ancestral types that could have been windborne from continents. + +In a similar way, winds carry insects from lowland regions to mountain tops, where they may be deposited in the snow. Those incapable of existing in this climatically rigorous environment (probably almost all) are eaten by the native arthropod fauna. In fact, the native arthropods may be dependent upon this wind-drifted food, just as some stream-dwelling insects are dependent for food upon the organic matter drifting down from upper levels of the stream. + +A study of the spotted alfalfa aphid (Therioaphis maculata) in California indicates that an amazingly large number of organisms are passively transported by wind. Mil- + +lions of these winged aphids alone float passively with the current in the spring months. + +Structural adaptations facilitating dispersal by wind are strongly developed in some groups of spiders. Gossamer, the silk secreted by the spider, is blown by the wind, and the spider, attached to it, is carried along, assisted sometimes by rising air currents. + +Adaptations for dispersal + +Water currents carry organisms in the same manner as wind. In the aquatic environment, however, the terrestrial organisms must stay afloat, avoid becoming saturated with water, and maintain their internal salt balance. Some outstanding examples of long distance passive dispersal by ocean currents are known. Marine invertebrates are carried from West Africa to South and Central America on the main equatorial current of the Atlantic. Some water in this current comes from the Niger and Congo rivers, so it is possible for estuarine and freshwater animals to be transported to another continent by this means as well. + +The distribution of several species of terrestrial animals is evidence that long distance dispersal has been achieved by major ocean currents. One dramatic example is the distribution of a flightless staphylinid beetle, Microlymma marinum, believed to have been carried passively from the Western hemisphere to the Eastern by means of the Gulf Stream. + +The odds are considerable against terrestrial organisms surviving the ordeal of a prolonged journey in the surface waters of the sea. Some vertebrates may actively participate in the travel by swimming, thereby increasing their chances of survival. Others may cling to floating debris or natural rafts of land or ice. Pieces of river banks or fringing swamp vegetation and soil break off and are carried out to sea, particularly when flood conditions prevail, and with the rafts go the animals that were stranded on them. Pack ice, breaking loose, can similarly function as a raft for polar animals, such as polar bears, foxes, etc. A remarkable floating island was observed in the Atlantic off the coast of North America in 1892. It was estimated to be 100 feet square, with trees 30 feet high, and to have drifted at least 1,000 miles. Whether it reached land and its plant and animal passengers were able to colonize the new land is not known, but this example at least demonstrates the feasibility of distribution of organisms on rafts. + +The distinction between airborne and waterborne means of dispersal is easy to make, but the two are not alternatives, because many organisms that start a journey on air complete it by water. Insects cross the Baltic Sea from Estonia to Finland, originally participating in mass flights, but reaching the other side in the water, many of them alive. + +Dispersal by other organisms. The third means of dispersal—by other organisms—may be regular, in the case of a host transporting a parasite, or irregular, as in the chance attachment of one organism to another. For parasites, finding a host is a major problem, and an efficient means of dispersal from one host to another or to the environment in which another can be found, is essential. Consequently, parasites have developed remarkable specializations to the life history characteristics of the host that enable the parasite to disperse at the most favourable time. Dispersal is often assisted by the use of an additional species as a transporting agent, or carrier, from one host to another. A case in point is the myxoma virus, which parasitizes rabbits and uses mosquitoes as carriers. When aided by wind, an individual mosquito can carry the virus as far as 40 miles before infecting a rabbit; by this process of transporting and infecting, the mosquito population can disperse the virus rapidly over a large area. + +Many organisms are distributed by attachment to mobile organisms. Small invertebrates such as snails and flatworms, for example, are accidentally transported on the legs of migrating birds. Undigested food items, such as the seeds of some plants, can be widely dispersed by their consumers in excrement deposited far from the source. There are numerous cases of mutualistic associations between animals and plants in which the plants are + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/15c_pg1_pg1_repeat1.md b/outputs/long_tiny_text/15c_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..da93725dca39a6879c03b6a5badbbcaf337a76ec --- /dev/null +++ b/outputs/long_tiny_text/15c_pg1_pg1_repeat1.md @@ -0,0 +1,35 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +The problem of discordance in atomic ages + +painted a generally gloomy picture for those seeking a chronometric tool—albeit a most revealing picture for those interested in geochemical processes. The gloom arises from the general discordance among isotopic ages based not only on uranium-235 and uranium-238 but also on thorium-232. The last radioisotope usually accompanies uranium because of its similar ionic charge and radius. + +Experience shows that, with the exception of results from the mineral uraninite, the three uranium-thorium-lead ages are almost always different. Why this should be so is the subject of many scientific papers and much experimental work. Clearly, discordance is not usually due to common lead. The presence of such lead is revealed through its nonradiogenic isotope lead-204 and is corrected for by calculations involving its isotopic composition; the latter is usually obtainable from cogenetic lead minerals (e.g., galena) found in physical association with the uranium mineral being dated. + +Where discordance generally seems to lie is in the failure of uranium-bearing minerals to be closed systems. This situation appears to prevail whether uranium is the dominant metal in the mineral or is merely a trace constituent. Whatever invalidates the closed-system assumption is beyond direct observation and must be inferred from analytical data on natural and laboratory-treated samples. It seems probable that lead loss is the most significant mechanism causing discordance. Of less certainty is the chronology of lead loss—specifically, whether it involved continuous diffusion beginning at the time of crystallization or was a relatively short-term process active only during a metamorphic event. + +The escape of helium is also significant. Derived from alpha particles, helium accumulates within a uranium mineral in a time-dependent manner similar to lead buildup. The main difference is that for every atom of uranium or thorium decaying there are six, seven, or eight helium atoms produced, depending on whether the parent atom is thorium-232, uranium-235, or uranium-238. The escape of some helium is predictable on the basis of its small mass and incompatibility with its environment in a crystal lattice. Furthermore, there is no isotopic way to recognize common helium, for it is also alpha-particle derived. As a consequence, uranium-helium dating has received far less attention than the various lead methods. At the present time, its application to the mineral magnetite seems reliable, provided that acid leaching first removes surficial material not held within the tight magnetite lattice. Increasingly significant is the application of uranium-helium dating to the shells of marine organisms that incorporate small numbers of uranium atoms into their calcium carbonate lattices. + +Potassium-40 to argon-40. Unlike uranium and thorium, the element potassium is of high average crustal abundance (about 2.5 percent) and occurs widely at concentrations where analysis is relatively easy. The fact that potassium is radioactive was recognized as early as 1905. Over 30 years went by, however, before potassium-40 was revealed as the radioactive isotope and another 20 years before its half-life was accurately determined. Because two decay modes are possible for potassium-40, one yielding stable argon-40 and the other stable calcium-40, potassium minerals accumulate two daughter elements. These build up in the ratio of eight calcium-40 atoms to one argon-40 atom. Clearly, once the production ratio of the two daughters has been accurately determined, both need not be measured in a radiometric-dating analysis. For example, the detection of eight trillion calcium-40 atoms in a sample implies the presence of one trillion argon-40 atoms and therefore the decay of nine trillion potassium-40 atoms over the life of the sample. + +Despite the relatively greater abundance of calcium-40, it is argon-40 that is almost always measured. The reason is simply that the calcium-40 isotope in common calcium is almost always so abundant that it overwhelms radiogenic calcium-40. Only a few potassium-bearing minerals, such as lepidolite and sylvite, form under conditions where the common calcium level is low enough not to mask radiogenic calcium-40. + +The two main problems that plague potassium-argon dating are like those of the uranium-lead method—common argon (sometimes called excess, or extraneous, argon) and argon leakage. Because of its inert chemical behaviour, argon tends to be almost totally excluded from most potassium-bearing minerals at the time they crystallize. Even so, minute amounts may enter the lattice and form a significant fraction of the argon-40 in samples younger than 100,000 years. Furthermore, there is no isotopic way to recognize the common argon, for it is pure argon-40 held in the crust since its formation by even earlier potassium-40 decay. + +Still another source of argon contamination is an atmospheric contribution adsorbed on surfaces at the time samples come in contact with air. A significant part of this is removable by heating in a vacuum at a temperature low enough to suppress the escape of radiogenic argon-40. Through measurements of nonradiogenic argon-38 and argon-36, what is left of the atmospheric portion can be recognized and corrected for. + +Far more serious than argon contamination is argon leakage. As was the case with the uranium-thorium methods, recognition is the first problem. It centres on age comparisons involving different decay schemes applied to the same rock samples. Specifically, search is made for potassium-bearing minerals associated with uraninite specimens that have shown concordant uranium-thorium-lead ages. The ubiquitous association of rubidium and potassium offers a second comparison of radiometric chronometers. As a result of such comparisons, supplemented by laboratory and field studies on leakage rates, potassium minerals have been evaluated with respect to the seriousness of argon loss. The results are much more encouraging than is true for uranium methods. Micas (biotite, muscovite, phlogopite) are especially good in retaining argon despite a priori arguments to the contrary. Hornblende is even better; potassium feldspar is poorer. Elevated temperatures—in excess of \(300^{\circ}\) C (about \(600^{\circ}\) F)—can change the rankings and ultimately cause intolerable leakage in all potassium minerals. It follows that the thermal history of a dated sample is very significant in determining how valid its potassium-argon age is. + +Rubidium-87 to strontium-87. The geochemical similarity of rubidium to potassium is most fortunate for radiometric geochronometry. The two elements occur not only in the same rock types but also in the same minerals. Moreover, from silicate meteorites to the various common types of terrestrial igneous rocks, the atomic ratio of potassium to rubidium remains more or less constant at about 600 (about 0.25 if just the two radioisotopes are considered). Consequently, almost every potassium-bearing sample carries two geochronometers within it—one involving the decay of potassium-40, the other based on the decay of rubidium-87. The age comparisons made possible are of incomparable value. + +The rubidium-strontium method is not without its problems—specifically, loss of the radiogenic daughter (strontium-87), presence of common strontium, and uncertainty about the half-life. Very little experimental work is available on which to judge strontium-87 retention by minerals. Experience in dating samples by different methods suggests the following order of decreasing retentivity, however: potassium feldspar > muscovite > biotite. Ages that are based on analyses of whole rocks show them to have the highest retention of all, an indication that those strontium atoms that do escape their parent mineral grains do not wander far. + +Common strontium is the rule rather than the exception. It is recognized through its nonradiogenic isotope strontium-86 and defined isotopically by measurements of associated rubidium-free minerals such as plagioclase feldspar and apatite. Calculation then suffices to remove the nonradiogenic strontium-87 contribution from the total strontium-87 content of a sample. + +The half-life of rubidium-87 has been a thorny problem that is still not fully resolved. The uncertainty centres on the difficulty of detecting every disintegration in a sample of rubidium-87. At a time when physicists were quot- + +Problems in the potassium-argon method + +Half-life of rubidium-87 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/15d_pg1_pg1_repeat1.md b/outputs/long_tiny_text/15d_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5e5d82fdbf58d07c66fb1d28e5ff67223a3c371a --- /dev/null +++ b/outputs/long_tiny_text/15d_pg1_pg1_repeat1.md @@ -0,0 +1,40 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +toes, tsetse flies, houseflies, and other nuisance insects, but rather in the large numbers of unfamiliar species that are an essential element in the food chains upon which all life depends. + +FORM AND FUNCTION + +External features of adult. General appearance. The thorax, abdomen, and legs of adult flies vary from long to short; the appearance of the fly is functional as well as decorative. Sometimes the bright colour and pattern of many flies is metallic (e.g., blow flies), but most often the fly is covered with a fine coating called tomentum or dusting. Many flies, particularly those of more highly evolved families, are bristly; and the strongest bristles have a precise location, particularly on the thorax. The arrangement of bristles and the identification method based on them is called chaetotaxy. + +Wings. Adult flies have only one pair of wings, on the mesothorax or second thoracic segment. The hind wings, modified into halteres, have a stalk and a knob, or club, that may be large and heavy relative to the size of the fly. The halteres vibrate up and down in time with the wings and act as gyroscopes in flight. If the fly yaws, rolls, or pitches during flight, the halteres, maintaining their original plane of movement, twist at their bases, where special nerve cells detect the twist and cause the fly to correct its flight attitude. + +Wing +venation + +The wings of flies have a defined pattern of veins; each has a name and characteristic location, often of taxonomic value. Few true flies have a reticulation (i.e., network of small veins) such as those in many other insects that are mistakenly called flies (e.g., mayflies, dragonflies, dobsonflies). Primitive flies tend to have complex wing venation, while advanced ones have reduced and simplified venation. Some of the small midges (e.g., Cecidomyiidae, Sciaridae, Mycetophilidae) have reduced wing venation also. Reduction or loss of wings occurs in many families, particularly those that inhabit windy places (e.g., mountains, islands) or caves, or that are external parasites among fur and feathers. + +Eyes. The eyes of flies often occupy most of the surface of the head, especially in males, where the eyes may meet in the middle line (holoptic). In female flies, with few exceptions, the eyes do not meet (dichoptic). In some families, notably robber flies and small acalyptate flies, both sexes are dichoptic. Parasitic flies, or those that live in secluded places, may have very small eyes or none at all. Typically, however, the compound eyes of flies contain many facets; for example, the housefly has 4,000 facets in each eye, about average for insects. + +Evolutionary specializations + +Mouthparts. The mouthparts of flies are adapted for sucking. Most flies have maxillae; many also have mandibles, elongate blades that overlie a groove in the labium and form a tubular channel for sucking liquids. In some females (e.g., bloodsucking flies, mosquitoes) the mandibles act as piercing stylets for drawing blood. Mandibles became functionless or were lost entirely relatively early in fly evolution and therefore bloodsucking families that evolved later had to develop other piercing methods. + +Tsetse flies and stable flies use the hardened labium; robber flies and dance flies use the hypopharynx; and Doli-chopodidae (small, metallic green flies with very long legs) envelop prey in the spongy labella of the labium and crush it with specially evolved teeth. Most flies suck their food; the few exceptions have reduced mouthparts and possibly do not feed at all as adults. Thus the food of flies must be liquid or solids that can be liquefied by saliva and stomach juices. Flies also have a pair of labial palpi equipped with sensory cells that act as organs of touch, taste, and smell. The palpi and the antennae are essential for examining possible food sources and suitable sites for egg laying. + +Antennae. All flies have antennae. Members of the suborder Nematocera (e.g., crane flies, various midges, and gnats) have whiplike antennae with two basal segments (scape and pedicel) and a flagellum of many similar segments. All other flies, properly called Brachycera, or short horns because the flagellum is contracted into a + +compound third segment, have remnants of the terminal flagellar segments remaining as a pencillike style or a bristle-like arista. Considerable antennal structural differences exist among related genera and species. + +Larval features. Larvae of flies have no wings, show no external traces of wingbuds (endopterygote insects), and do not have segmented thoracic legs. Larvae of primitive flies (most Nematocera and Brachycera) have a well-developed head, with chewing mouthparts. Evolution has favoured reduction of the head capsule and replacement of chewing mouthparts with a pair of mouth hooks that move in a vertical plane. Larvae with adaptive external structures (e.g., prolegs) generally belong to the Nematocera or Brachycera. The maggots of the Cyclorrhapha have little external structure other than black mouth hooks and the posterior spiracles. Although a few of these larvae show secondary complexities (e.g., some aquatic larvae of hover flies and shore flies), most cannot be identified beyond the family level. + +Nutritional requirements. Adults. Nutrition involves balance between feeding habits of larval and adult flies. Primary feeding occurs during the larval stage; adult feeding serves to compensate the shortcomings of larval nourishment. At one extreme are nonbiting midges, with larvae that vigorously filter micro-organisms from water; the adults do not feed. Related to nonbiting midges are biting midges, mosquitoes, and black flies; adult females in these families must supplement an insufficient larval diet. Although one batch of eggs occasionally is laid without a meal of blood, blood is necessary to mature a second batch. Flies that lay one batch of eggs without blood are autogenous; those that cannot lay at all without blood are anautogenous. One species can have both types, possibly as a result of shifting populations or races arising from natural selection. For example, in the far north large populations of biting flies (e.g., mosquitoes, biting midges, black flies, horse flies) occur during the short Arctic summer; obviously there are insufficient numbers of warm-blooded animals to provide food. If the flies find blood, they use it; if not, they still survive. + +Blood, +pollen, and +nectar + +Most adult flies visit flowers, which provide water, nectar, and pollen. Pollen, more difficult for a sucking insect to obtain than blood, is rich in protein and is an important source of this nutrient. Certain hover flies crush pollen grains between hardened portions of the labella before swallowing them; many flies actively probe into flowers, covering their heads and eyes with pollen grains. Nectar from flowers contains carbohydrates, and most adult flies use this syrupy liquid. Although their role in pollination is less well known than that of bees, flies are important pollinators of flowers. Some plants (e.g., spurges) are often covered with small flies of different families. Small flies also feed on honeydew from aphids (see HOMOPTERA). Although the name Drosophila means "lover of dew," this insect sucks water and any other obtainable fluid. Flies feed on dung and liquid products of either animal or vegetable decay. They obtain nutrients from farmyard manure heaps and garbage dumps. These places also harbour many larvae that feed either directly on available organic food or are carnivorous on other larvae. A familiar example is the yellow dung fly; adults prey on other insects visiting the dung. + +Larvae. The adaptability of flies is evident in the wide range of foods that larvae eat. Apart from parasites, the most specialized feeders are larvae that live in plant tissues (e.g., leafmining Agromyzidae, many restricted to one plant species or group). Generally agricultural and horticultural pests (e.g., cabbage root fly) are versatile species, feeding on a variety of wild hosts and modifying their diets when presented with concentrated plantings of commercial crops. Many carnivorous fly larvae (e.g., asilids) probably live in soil and eat vegetable or animal matter, whichever is available. Since adult asilids (robber flies), however, feed on other insects, the larval nourishment is presumed to be inadequate. Some larvae, particularly maggots, that feed on vegetable matter during the first and second instars, become carnivorous during the third instar, when most of the growth takes place. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/15e_pg1_pg1_repeat1.md b/outputs/long_tiny_text/15e_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8d413d6748c89f77db8d4a3d92eea2e8b12834ad --- /dev/null +++ b/outputs/long_tiny_text/15e_pg1_pg1_repeat1.md @@ -0,0 +1,42 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +the products of protein digestion stimulate the antrum to release additional quantities of gastrin. Gastrin then stimulates parietal cells to secrete large amounts of hydrochloric acid. As the contents of the stomach become more and more acid, the acid chyme comes in contact with the antral mucosa. This then inhibits the release of gastrin from the antrum. Thus, there is a "feedback" mechanism related to the degree of acidity of the gastric contents. When the contents of the gastric antrum are less acid the mucosa releases gastrin. When the contents of the gastric antrum are more acid the release of gastrin is inhibited. + +Another humoral substance that regulates gastric secretion is enterogastrone, a gastrointestinal hormone released from the duodenum in response to stimulation by various types of food coming in contact with the duodenal mucosa. Fat is the most potent stimulus for the release of the hormone. Enterogastrone inhibits both gastric secretion and gastric motility. Thus, as food enters the duodenum from the stomach, enterogastrone acts as a brake on both gastric emptying and gastric secretion. Two additional hormones, glucagon from the pancreas and secretin from the duodenal mucosa, exert some inhibitory effects on gastric secretion. + +Gastric digestion. Digestion is not carried to completion in the stomach. Experimental evidence in man shows that approximately 30 to 50 percent of ingested starches and approximately 10 to 15 percent of ingested protein may be digested in the stomach. Little, if any, of ingested fat is digested there. Thus, the stomach is not primarily a digestive organ and is not essential to life. Its main function is to convert the ingested meal into chyme by mixing it with gastric juice in preparation for delivery into the small intestine, where most of the digestive processes occur. + +Digestion of carbohydrates. When a meal has been thoroughly chewed and adequately mixed with saliva, the amylase in the saliva will continue its digestive action on starches in the stomach as long as the acidity of the gastric contents is not too high. Each digestive enzyme has an optimum hydrogen ion concentration, or pH, at which it can function most effectively. The optimum pH of amylase is approximately 6.8, slightly on the acid side of neutral (7.0). Thus, as the gastric contents are mixed with gastric juice and hydrochloric acid, the pH of gastric contents decreases (i.e., becomes more acid) and the amylase activity diminishes accordingly. + +Digestion of proteins. The proteolytic enzyme secreted in the gastric juice is pepsin. Pepsin has an optimum pH of approximately 2.0 and splits proteins mainly into the less complex proteose and peptone fragments of the protein molecules. Few amino acids or polypeptides are released from protein by the action of pepsin. Thus, protein digestion in the stomach is only partial—about 10 to 15 percent, as mentioned previously. Gastric secretion in response to a meal will have the highest concentration of pepsin within the first hour. As the volume of gastric juice increases, the concentration of pepsin falls. During the later stages of gastric digestion, when the volume of gastric juice diminishes, the concentration of pepsin increases. + +Pepsin is not the only proteolytic enzyme in gastric juice. Others include cathepsin and gastricin. These proteolytic enzymes have an optimum pH of 4.0 and 3.0, respectively. Their activity is of relatively minor importance. + +Digestion of fats. Little if any digestion of fats normally occurs in the human stomach. There is some evidence, however, for a gastric lipase, a tributerase with an optimum pH between 4.0 and 5.0 and inactive at pH below 2.5. The origin of this lipase is unknown and it acts only on short-chain fats; i.e., those with less than five carbon atoms. Much of the fat in the human diet contains 18 carbons in the fatty acid chains; tributerase has little if any activity on these fats and is of negligible significance. + +Gastric absorption. Although the stomach absorbs few products of digestion, it is capable of absorbing a great many other substances. + +Foodstuffs. Components of the diet that can be absorbed through the gastric mucosa include glucose and other simple sugars, amino acids, and some fat-soluble substances. + +Water. Water moves freely from the gastric contents across the gastric mucosa into the blood. The net absorption of water from the stomach, however, is small, because water moves just as easily from the blood across the gastric mucosa to the lumen of the stomach. To demonstrate absorption of water from the stomach, isotopic, or "heavy," water is introduced into the stomach by a tube, and the presence of the isotope in the blood is then determined. In man about 60 percent of heavy water placed in the stomach is absorbed into the blood in 30 minutes. In normal young adults the mean rate of water absorption from the stomach is about 2 percent of the gastric contents per hour. + +Alcohol and drugs. A number of alcohols, including ethyl alcohol, are readily absorbed from the stomach. The membranes of the cells that line the stomach are composed of lipids or fat substances, thus items in the diet that are fat soluble penetrate the membranes of the cells lining the stomach. Since ethyl alcohol and a number of other drugs are somewhat soluble in fat, they are absorbed directly from the stomach. The pH of the gastric contents also determines whether or not some substances will be absorbed. At a very low pH, for example, aspirin is absorbed almost as rapidly as water from the stomach, but as the pH of the stomach rises it is absorbed much more slowly. + +Gastric emptying. Gastric emptying time is determined by the rate of the antral pumping contractions (three per minute) and the volume of material emptied into the duodenum by each antral contraction. The stroke volume of each antral contraction varies, depending upon the nature of the contents being pumped. Usually, however, this amounts to volumes of three to five mililitres for each antral contraction. + +An ordinary meal is usually completely emptied from the stomach in two to three hours. Both the physical and chemical composition of the meal influence the emptying rate. Fluids are emptied more rapidly than solids, carbohydrates more rapidly than proteins, and proteins more rapidly than fats. Liquid meals that are isotonic to blood, that is, having the same osmotic pressure as blood, are emptied more rapidly than hypotonic or hypertonic liquids. Different substances are emptied from the stomach at differing rates because of the various neural and humoral factors that regulate gastric emptying. + +When food is received into the stomach from the esophagus, it tends to form concentric layers. The contents at the periphery of the ingested meal are in contact with the gastric mucosa where they are mixed with the gastric secretions and subjected to the contracting waves of the wall of the stomach. As the peristaltic waves pass over the intragastric contents they tend to push the liquefied peripheral portion of the gastric contents into the antrum. When the antrum becomes compartmentalized from the body of the stomach, its liquid contents are pumped into the duodenum. The process is repetitive and constant until the stomach is emptied. + +DIGESTION IN THE SMALL INTESTINE + +The small intestine is the principal digestive organ of the human alimentary canal. Three principal activities within the small intestine are especially adapted for its role in digestion: (1) its motor activity allows both mixing and transport of intraluminal contents; (2) secretions into the small intestine provide the necessary enzymes and other constituents essential for normal digestion; (3) it has highly selective absorptive capabilities. These absorptive functions of the small intestine are made possible by the specialized structures of the intestinal mucosa that line the small bowel. + +The morphology of the small intestine is arranged so that the inner mucosal surface, in contact with the intraluminal contents, greatly exceeds the external surface area. Some of the increased internal surface area is due to special folds in the intestinal mucosa known as plicae + +Emptying +time + +Morphology of the small intestine + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/16a_pg1_pg1_repeat1.md b/outputs/long_tiny_text/16a_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ef8fd490a5a445cd2af0b49cab5e70b4865de6a7 --- /dev/null +++ b/outputs/long_tiny_text/16a_pg1_pg1_repeat1.md @@ -0,0 +1,109 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +crest-fall-en (krest'fōlan), adj. 1. dejected; dispirited; depressed. 2. with drooping crest. —crest/fall/en-ly, adv. crest-ing (kres'ting), n. 1. Archit. a decorative coping, balustrade, etc., usually designed to give an interesting skyline. 2. Furniture, ornamentation carved or sawed in or added to the top rail of a piece of furniture. + +cre-ta-ceous (kri tā'shās), adj. 1. of the nature of, resembling, or containing chalk. 2. (cap.) Geol. noting or pertaining to a period of the Mesozoic era occurring from 70,000,000 to 135,000,000 years ago and characterized by the extinction of the giant reptiles and the advent of modern insects. See table at era. —n. 3. (cap.) Geol. the Cretaceous period or system. [< L crētāceus = crēt(a) chalk (lit., Cretan earth) + -āceus -ACEOUS] —cre-ta/ceous-ly, adv. + +Crete (krēt), n. a Greek island in the Mediterranean, SE of Greece. 483,258 (1961); 3235 sq. mi. Cap.: Canea. Also called Candia. —Cre'tan, adj., n. + +cre-tin (krēt'ən, krē'tin), n. 1. a person suffering from cretinism. 2. a stupid, obtuse, or mentally defective person. [< F; SwissF creitin, crestin lit., Christian, i.e., a human being though an idiot] —cre'ti-noid', adj. —cre'tin-ous, adj. + +cre-tin-ism (krēt'əniz'əm), n. Pathol. a chronic disease due to absence or deficiency of the normal thyroid secretion, characterized by physical deformity, dwarfism, idiocy, and, often, goiter. [< F crétinisme] + +cre-tonne (kri ton', krē'ton), n. a heavy cotton material in printed designs, used esp. for drapery and slip covers. [< F. after Creton, Norman village where it was produced] + +Cre-ū-sa (krē ōo'sa), n. Class. Myth. 1. Also called Glauce, the bride of Jason, slain by the magic of the jealous Medea. 2. a daughter of Priam and the wife of Aeneas. + +cre-val-le (krō val/ē, -val'a), n., pl. (esp. collectively) -le, (esp. referring to two or more kinds or species) -les, any of several marine fishes of the jack family, Carangidae. [var. of cavalla < Sp caballa horse mackerel < caballo horse < L caballus] + +cre-vasse (kra vas'), n., v., -vassed, -vas-sing. —n. 1. a fissure or deep cleft in glacial ice or the earth's surface. 2. a breach in an embankment or levee. —t. 3. to fissure with crevasses. [< F; see CREVICE] + +Crève-coeur (krev kær'), n. Michel Guil-laume Jean de (mē shel' gē yom' zhān dā), (pen name: J. Hector St. John), 1735-1813, French writer, statesman, and agriculturalist; in U.S. after 1754. + +crev-ice (krev/is), n. a crack forming an opening; cleft; fissure. [ME crecace < MF, OF < crev(er) (to) crack (< L crepāre) + -asse n. suffix] —crev/iced, adj. + +crew\(^{1}\) (krōō), n. 1. a group of persons involved in a particular kind of work or working together: the crew of a train; a wrecking crew. 2. Naut. a. the company of men who man a ship or boat. b. one or all of the common sailors of a ship's company. 3. the team that mans a racing shell: varsity crew. 4. the sport of racing with racing shells: He went out for crew in his freshman year. 5. Archaic. any force or band of armed men. 6. Informal. a company; crowd. —v.i. 7. to serve as crew. [late ME creve augmentation, hence reinforcements, body of soldiers < MF creve increase, n. use of fem. of OF creu, ptp. of creistre to grow < L crescere; see CRESCENT] + +crew\(^{2}\) (krōō), v. a pt. of crow\(^{2}\). + +crew' cut', a man's haircut in which the hair is closely cropped. + +crew-el (krōō'/al), n. 1. Also called crew/el yarn', a worsted yarn for embroidery and edging. 2. crewelwork. [late ME crule] —crew/el-ist, n. —crew/el-like', adj. + +crew-el-work (krōō'/al wŏrk'), n. decorative embroidery done with worsted yarn on cotton or linen, using simple stitches worked in floral designs. [late ME crule yarn] + +crew' neck', a collarless neckline, as on a sweater or jersey, that fits snugly at the base of the neck. —crew'neck', crew'-necked', adj. + +crib (krib), n., v., cribbed, crib-bing. —n. 1. a child's bed with enclosed sides. 2. a stall or pen for cattle. 3. a rack or manger for fodder, as in a stable or barn. 4. a small house or room. 5. any confined space. 6. a wicker basket. 7. Building Trades, Civil Engineering, any of various cellular frameworks assembled in layers at right angles, used in the construction of foundations, dams, retaining walls, etc. 8. a lining for a well or other shaft. 9. a bin for storing grain, salt, etc. 10. a barrier projecting part of the way into a river and then upward, acting to reduce the flow of water and as a storage place for logs being floated downstream. 11. Brit., Australian, lunch carried from home and eaten by a laborer on the job; snack. 12. Informal. a petty theft, plagiarism, etc. 13. Informal. a translation, list of correct answers, or other illicit aid used by students, as while reciting, taking exams, or the like; pony. 14. Cribbage, a set of cards made up by equal contributions from each player's hand and belonging to the dealer. —t. 15. to confine in or as in a crib. 16. to provide with a crib or cribs. 17. to line with timber or planking. 18. Informal. to pilfer or steal, esp. to plagiarize (another's writings or ideas). —t. 19. Informal. to use a crib in translating. 20. (of a horse) to practice cribbing. 21. Informal. to steal; plagiarize. [ME cribbe, OE crib(b); c. D krib, G Krippe] —crib/ber, n. + +crib-bage (krib/ij), n. a card game, basically for two players in which the object is to make counting combinations for points that are scored on a small board (crib/bage board/) having holes for pegs. + +crib-bing (krib/ing), n. 1. Also called crib-bit-ing (krib/-bi/ting), wind-sucking, an injurious habit in which a horse bites its manger and as a result swallows air. 2. Mining. a. a timber lining, closely spaced, as in a shaft. b. pieces of timber for lining a shaft, raise, etc. 3. a system of cribs, as for a building or the like having its foundations rebuilt. + +crib-ri-form (krib/ra fŏrm'), adj. sievelike. Also, crib-rous (krib/ras). [< L cribr(um) a sieve + -i- + -FORM] + +Crich-ton (krit'ən), n. James (“the Admirable Crichton”), 1560?–82, Scottish scholar, adventurer, and linguist. + +crick\(^{1}\) (krik), n. 1. a sharp, painful spasm of the muscles, as of the neck or back, making it difficult to move the part. —t. 2. to give a crick or wrench to (the neck, back, etc.). [late ME crikke, perh. akin to crick\(^{2}\)] + +crick\(^{2}\) (krik), n. U.S. Dial. creek (def. 1). + +Crick (krik), n. Francis Harry Compton, born 1916, English biophysicist: Nobel prize for medicine 1962. + +crick-et\(^{1}\) (krik/it), n. 1. any of several saltatorial, orthopodous insects of the family Gryllidae, characterized by long antennae and stridulating organs on the forewings of the male. 2. a metal toy consisting of a convex metal piece with a flat metal spring fastened to it at one side that snaps back and forth with a clicking, cricketlike noise when pressed. [ME criket insect < MF criquet = criqu(er) (to) creak (imit.) + -et -er] + +crick-et\(^{2}\) (krik/it), n. 1. a game for two teams of 11 members each that is played on a large field having two wickets 22 yards apart, the object being to score runs by batting the ball far + +Cricket, +Gryllus domesticus +(Length \(\frac{3}{4}\) in.) + +enough so that one is enabled to exchange wickets with the batsman defending the opposite wicket before the ball is recovered. 2. fair play; gentlemanly conduct: It wouldn't be cricket to give away his secret. —v.i. 3. to play cricket. [< MF criquet goal post < M Flem krick kind of stick; see -ET] —crick/et-er, n. + +crick-et\(^{3}\) (krik/it), n. a small, low stool. [?] + +cri-cold (kri'koid), Anat. —n. 1. a ring-shaped cartilage at the lower part of the larynx. —adj. 2. of or pertaining to the cricoid cartilage. [< NL cricoid(es) < Gk krikoeidès ring-shaped] + +cried (krid), v. pt. of cry. + +cri-er (kri'ar), n. 1. a person who cries. 2. a court or town official who makes public announcements. 3. a hawker. [ME criere < OF] + +crim., criminal. + +crime (krim), n. 1. an action or an instance of negligence that is deemed injurious to the public welfare or morals or to the interests of the state and that is legally prohibited. 2. the habitual or frequent performance of crimes: a life of crime. 3. criminal activity and those engaged in it. 4. any offense, esp. one of grave character. 5. serious wrongdoing; sin. 6. Informal. a foolish, senseless, or shameful act: It's a crime to overfeed a dog like that. [ME < OF < L crimin- (s. of crimen) charge, guilt, crime] + +—Syn. 1. wrong; misdemeanor, tort, felony. CRIME, OFFENSE agree in meaning a breaking of law. CRIME usually means any serious violation of human laws: the crime of treason, of robbery. OFFENSE is used of an infraction of either human or divine law: an offense leading to a jail sentence; an offense against morals. + +Crime-a (kri mē'ə, kri-), n. 1. a peninsula in the SW Soviet Union in Europe, between the Black Sea and the Sea of Azov. 2. a former autonomous republic of the Soviet Union, now a region of the Ukraine. ab. 10,000 sq. mi. —Crime'an, adj. + +Crime'an War', a war (1853-56) fought by Great Britain, France, Turkey, and Sardinia against Russia, chiefly in the Crimea. + +criminal (krim'ə nəl), adj. 1. Law. of or pertaining to crime or its punishment. 2. of the nature of or involving crime. 3. guilty of crime. 4. Informal. senseless; foolish: It's criminal to waste so much time. —n. 5. a person guilty or convicted of a crime. [late ME < LL criminal(is)] —crim/i-nal-ly, adv. —Syn. 2. felonious, unlawful, illegal. 5. convict, culprit, felon, crook, gangster. —Ant. 2. lawful. 3. innocent. + +criminal assault', Law. 1. an attack by physical force on a person for which the attacker is liable to criminal prosecution. 2. a similar act with intent to commit rape. + +criminal contempt', Law. an act considered to be committed against the dignity or authority of a court and liable to punishment imposed by a judge. + +criminal conversation, Civil Law. adultery. + +criminality (krim'ə nal/i tē), n., pl. -ties for 2. 1. the quality or state of being criminal. 2. a criminal act or practice. [< ML criminālitās] + +criminal law', laws dealing with criminal offenses and their punishments. + +crim-inate (krim'ə nāt'), v.t., -nat-ed, -nat-ing. 1. to charge with a crime. 2. to incriminate. 3. to censure (something) as criminal; condemn. [< L crimināt(us) accused, ptp. of crimināri] —crim/i-na/tion, n. —crim/i-na/tive, crim-i-na-tor-y (krim'ə nā tŏr/ē, -tŏr/ē), adj. —crim/i-na/tor, n. + +crim-i-nol-o-gy (krim'ə nol'ə jē), n. the study of crime and criminals. [< L crimin- (s. of crimen; see CRIME) + -o- + -LOGY] —crim-i-no-log-i-cal (krim'ə nēloj/i kal), crim/i-no-log/ic, adj. —crim/i-no-log/i-cal-ly, adv. —crim/i-nol/o-gist, n. + +crim-mer (krim'ar), n. krimmer. + +crimp\(^{1}\) (krimp), v.t. 1. to press into small, regular folds; make wavy; corrugate. 2. to bend (leather) into shape. 3. to curl (hair), esp. with the use of a curling iron. 4. Metal-working. a. to bend the edges of (skelp) before forming into a tube. b. to fold the edges of (sheet metal) to make a lock seam. 5. to produce a corrugated surface in; corrugate, as sheet metal, cardboard, etc. 6. to press or draw together, as the ends of something. 7. Cookery. to gash (the flesh of a fish) with a knife to make it more crisp when cooked. 8. to check; arrest; hinder: The shortage of materials crimped production. —n. 9. the act of crimping. 10. a crimped condition or form. 11. Usually, crimps, waves or curls, esp. in hair that has been crimped or that displays a crimped pattern. 12. the waviness of wool fibers as naturally grown on sheep. 13. a crease formed in sheet metal or plate metal for fastening purposes or to make the material less flexible. [ME crymp(en), OE (ge)crympan to curl < crump crooked] —crimp'er, n. + +crimp\(^{2}\) (krimp), n. 1. a person engaged in enlisting seamen, soldiers, etc., by persuasion, swindling, or coercion. —t.t. 2. to enlist (seamen, soldiers, etc.) by such means. [special use of CRIMP\(^{1}\)] + +crim-ple (krim'/pəl), v.t., v.i., -pled, -pling. to wrinkle, crinkle, or curl. [ME crymple] + +crimp-y (krim'/pē), adj., crimp-i-er, crimp-i-est. of a crimped form or appearance. + +crim-son (krim'zən, -sən), adj. 1. deep purplish-red. —n. 2. a crimson color, pigment, or dye. —v.t., v.i. 3. to make or become crimson. [late ME crym(e)syn < OSp + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/16b_pg1_pg1_repeat1.md b/outputs/long_tiny_text/16b_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b47f81d9dc0f9207d9627652d1790639817346b1 --- /dev/null +++ b/outputs/long_tiny_text/16b_pg1_pg1_repeat1.md @@ -0,0 +1,101 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +de-scry (di skri'), v.t., -scried, -scry-ing. 1. to make out (something unclear or distant) by looking carefully; discern. 2. to discover; detect. [ME descrie(r) < OF decri(er) (to) proclaim, de-cry. See dis-1, cry] —de-scri'er, n. + +des-e-crate (des/a krat'), v.t., -crat-ed, -crat-ing. 1. to divert from a sacred to a profane use or purpose. 2. to treat with sacrilege; profane. [DE- + (CON)SECRATE] —des/e-crat'er, des/e-cra/tor, n. —des/e-cra'tion, n. + +de-seg-re-gate (dē seg/rə gāt'), v., -gat-ed, -gat-ing. —v.t. 1. to eliminate racial segregation in: to desegregate all schools. —v.i. 2. to eliminate racial segregation. + +de-seg-re-gation (dē/seg rə gā/shan, dē seg/-), n. the elimination of laws, customs, or practices that restrict different races, groups, etc., to specific or separate schools and other public facilities, neighborhoods, etc. + +de-sen-si-tize (dē sen/si tiz'), v.t., -tized, -tiz-ing. 1. to lessen the sensitiveness of. 2. to make indifferent in feeling, unaware, or the like. 3. Physiol. to eliminate the natural or acquired reactivity or sensitivity of (an animal, organ, tissue, etc.) to an external stimulus, as an allergen. 4. Photog. to make less sensitive or wholly insensitive to light, as the emulsion on a film. —de-sen/si-ti-za'tion, n. —de-sen/si-tiz'er, n. + +des-ert\(^{1}\) (dez/art), n. 1. a region so arid that it supports only sparse vegetation or none at all. 2. any area in which few forms of life can exist because of lack of water, permanent frost, or absence of soil. 3. any place lacking in something, usually as specified: The town was a cultural desert. —adj. 4. of, pertaining to, or like a desert; desolate; barren. 5. occurring, living, or flourishing in the desert: a desert tribe. [ME < OF < eccl. L desert(um) (neut.), n. use of ptp. of deserere to abandon, forsake = de- DE- + serere to join together (in a line); cf. SERIES] + +—Syn. 1. DESERT, WASTE, WILDERNESS refer to areas that are uninhabited. DESERT emphasizes lack of water; it refers to a dry, barren, treeless region, usually sandy: an oasis in a desert; the Sahara Desert. WASTE emphasizes lack of inhabitants and of cultivation; it is used of wild, barren land, but figuratively the word is also applied to turbulent seas: a desolate waste; a terrifying waste of water. WILDERNESS emphasizes the difficulty of finding one's way because of barrenness or of luxuriant vegetation; it is also applied to the ocean, esp. in stormy weather: a trackless wilderness. + +de-sert\(^{2}\) (di zūrt'), v.t. 1. to leave (a person, place, etc.) without intending to return, esp. in violation of a duty, promise, or the like; abandon; forsake: He deserted his wife. —v.i. 4. to forsake or leave one's duty, obligations, or the like (sometimes fol. by from, to, etc.). [< F désert(er) < LL désertare, freq. of L deserere; see DESERT\(^{1}\)] —de-sert'er, n. —Syn. 1. DESERT, ABANDON, FORSAKE mean to leave behind persons, places, or things. DESERT implies intentionally violating an oath, formal obligation, or duty: to desert campaign pledges. ABANDON suggests giving up wholly and finally, whether of necessity, unwillingly, or through shirking responsibilities: to abandon a hopeless task. FORSAKE has emotional connotations, since it implies violating obligations of affection or association: to forsake a noble cause. + +de-sert\(^{3}\) (di zūrt'), n. 1. Often, deserts, reward or punishment that is deserved: to get one's just deserts. 2. the fact of deserving reward or punishment. 3. merit or virtue. [ME < OF deserte, n. use of fem. ptp. of desereir to DESERVE] + +de-sert-ed (di zūr'tid), adj. 1. abandoned; forsaken. 2. untenanted; without inhabitants. 3. unfrequented; lonely. + +de-ser-tion (di zūr/shan), n. 1. the act of deserting. 2. the state of being deserted. 3. Law, willful abandonment, esp. of one's spouse without consent, in violation of legal or moral obligations. 4. Mil. leaving or running away from service or duty without the intention of returning. Cf. A.W.O.L. [< LL désertion- (s. of désertiō)] + +de-serve (di zūrv'), v., -served, -serv-ing. —v.t. 1. to merit or have a claim to (reward, assistance, punishment, etc.) because of one's acts, qualities, or situation. —v.i. 2. to be worthy of, qualified for, or have a claim to reward, punishment, recompense, etc. [ME deserve(n) < OF deserv(ir), L déservire to serve zealously] —de-serv'er, n. + +de-served (di zūrvd'), adj. justly earned; merited. —de-serv-ed-ness (di zūr'vid nís), n. + +de-serv-ed-ly (di zūr'vid lē), adv. justly; rightly. + +de-serv-ing (di zūr'viŋ), adj. worthy of reward, praise, or help. —de-serv/ing-ly, adv. —de-serv/ing-ness, n. + +de-sex (dē seks'), v.t. 1. to castrate or spay. 2. to deprive of sex, sex appeal, or sexual interest. + +de-sex-u-al-ize (dē sek/shōō a liz'), v.t., -ized, -iz-ing. desex. —de-sex/u-al-i-za'tion, n. + +des-ha-bille (dez/a bēl', -bē'), n. dishabille. + +des-ic-cant (des/a kānt), adj. 1. desiccating, as a medicine. —n. 2. a drying substance or agent. [< L desiccant- (s. of desiccāns), prp. of desiccāre to dry up] + +des-ic-cate (des/a kāt'), v., -cat-ed, -cat-ing. —v.t. 1. to dry thoroughly; dry up. 2. to preserve (food) by removing moisture; dehydrate. —v.i. 3. to become thoroughly dried or dried up. [< L desiccāt(us) dried up, ptp. of desiccāre = de- DE- + siccāre < sicc(us) dry; see -ATE\(^{1}\)] —des/ic-ca'tion, n. —des/ic-ca'tive, adj. + +des-ic-cat-ed (des/a kā'tid), adj. dehydrated. + +des-ic-ca-tor (des/a kā'tor), n. 1. a person or thing that desiccates. 2. an apparatus for drying fruit, milk, etc. 3. Chem. an apparatus for absorbing moisture in a substance, esp. an airtight, usually glass container containing calcium chloride or some other drying agent. + +de-sid-er-a-ta (di sid/ə rā'tə), n. pl. of desideratum. + +de-sid-er-ate (di sid/ə rāt'), v.t., -at-ed, -at-ing. to wish or long for; want; desire. [< L desiderāt(us) longed for (ptp. of desiderāre) = de- DE- + sider- (s. of sidus) star + -ātus -ATE\(^{1}\)] —de-sid'er-a'tion, n. + +de-sid-er-a-tive (di sid/ə rā'tiv, -or ə tiv), adj. 1. having or expressing desire. 2. Gram. (of a verb derived from another verb) expressing desire to perform the action denoted by the underlying verb. —n. 3. Gram. a desiderative verb. + +de-sid-er-a-tum (di sid/ə rā'tam), n., pl. -ta (-tə). something wanted or needed. [< L, n. use of neut. ptp. of desiderāre; see DESIDERATE] + +de-sign (di zin'), v.t. 1. to prepare the preliminary sketch + +or the plans for (a work to be executed), esp. to plan the form and structure of: to design a new bridge. 2. to plan and fashion artistically or skillfully. 3. to intend for a definite purpose: a scholarship designed for medical students. 4. to form or conceive in the mind; contrive; plan. 5. to assign in thought or intention; purpose. 6. Archaic. to mark out, as by a sign; indicate. —v.i. 7. to make drawings, preliminary sketches, or plans. 8. to plan and fashion the form and structure of an object, work of art, decorative scheme, etc. —n. 9. an outline, sketch, or plan, as of the form and structure of a work of art. 10. the organization or structure of formal elements in a work of art; composition. 11. the pattern or motif of an artistic work. 12. the art of designing. 13. a plan or project. 14. a plot or intrigue. 15. intention; purpose; end. [ME design(en) < L design(āre) (to) mark out] —Syn. 4. devise, project. 13. See plan. + +des-ig-nate (e. dez/ig nāt'; adj. dez/ig nit, -nāt'), v., -nat-ed, -nat-ing, adj. —v.t. 1. to mark or point out; specify. 2. to denote; indicate. 3. to name; entitle; style. 4. to nominate or select for a duty, office, purpose, etc. —adj. 5. named or selected for an office, position, etc., but not yet installed (often used in combination following the noun it modifies): ambassador-designate. [ME < L designāt-(us), ptp. of designāre] —des/ig-na/tive, des/ig-na-to-ry (dez/ig nō tōr/ē, -tōr/ē, dez/ig nā'tə rē), adj. —des/ig-na/tor, n. + +des/ignated' hit/ter, Baseball. a hitter selected prior to the start of the game to bat for the starting pitcher and all subsequent pitchers without otherwise affecting the status of the pitchers in the game. Abbr.: dh + +des-ig-na-tion (dez/ig nā/shan), n. 1. the act of designating. 2. the fact of being designated. 3. a distinctive name or title. 4. a nomination, appointment, or election. [ME designacion < L designātiō- (s. of designātiō) a marking out] + +de-signed (di zind'), adj. made or done by design; intended; planned. —de-sign-ed-ly (di zi'nid lē), ade. + +des-ig-nee (dez/ig nē'), n. a person who is designated. [DESIGN(ATE) + -EE] + +de-sign-er (di zi'nər), n. 1. a person who devises or executes designs for works of art, dresses, machines, or stage sets. 2. a schemer, intriguer, or plotter. + +de-sign-ing (di zi'ning), adj. 1. scheming; intriguing; artful; crafty. 2. showing or using forethought. —n. 3. the act or art of making designs. —de-sign/ing-ly, adv. + +des-i-nence (des/a nans), n. 1. a termination or ending, as the final line of a verse. 2. Gram. a termination, ending, or suffix of a word. [< F < ML desinentia = L desinent- (s. of desinēns), prp. of desinere to put down, leave (de- DE- + sinere to leave) + -ia; see -ENCE] —des/i-nent, des-i-nen-tial (des/ə nen'shōl), adj. + +de-sir-a-ble (di zi'r/a bal), adj. 1. worth desiring; pleasing, excellent, or fine. 2. arousing desire or longing: a desirable woman. 3. advisable; recommendable: a desirable law. —n. 4. a person or thing that is desirable. [ME desirable < OF] —de-sir/a-bil/i-ty, n. —de-sir/a-bly, adv. + +de-sire (di zi'r'), v., -sired, -sir-ing, n. —v.t. 1. to wish or long for; crave; want. 2. to express a wish to obtain; ask for; request. —n. 3. a longing or craving: a desire for fame. 4. an expressed wish; request. 5. something desired. 6. sexual appetite or a sexual urge. [ME desire(n) < OF desir(er) < L desiderāre; see DESIDERATE] —de-sir'er, n. + +—Syn. 1. covet, fancy. See wish. 2. solicit. 3. aspiration, hunger, appetite, thirst. DESIRE, CRAVING, LONGING, YEARNING suggest feelings that impel a person to the attainment or possession of something. DESIRE is a strong feeling, worthy or unworthy, that impels to the attainment or possession of something: a desire for success. CRAVING implies a deep and imperative wish for something, based on a sense of need and hunger (literally or figuratively). A LONGING is an intense wish, generally repeated or enduring, for something that is at the moment beyond reach but may be attainable at some future time: a longing to visit Europe. YEARNING suggests persistent, uneasy, and sometimes wistful or tender longing. —Ant. 1. reject, loathe. + +de-sir-ous (di zi'r'as), adj. having or characterized by desire; desiring. [ME < OF desireus] —de-sir'ous-ly, adv. —de-sir'ous-ness, n. + +de-sist (di zist', -sist'), v.i. to cease, as from some action or proceeding; stop. [ME < OF desist(er) < L desistere to leave off = de- DE- + sistere to stand, place, redupl. form of stare to stand] —de-sist/ance, de-sist/ence, n. + +desk (desk), n. 1. an article of furniture having a broad, usually level, writing surface, as well as drawers or compartments for papers, writing materials, etc. 2. a frame for supporting a book from which the service is read in a church. 3. a pulpit. 4. the section of a large organization, as a governmental bureau, newspaper, etc., having responsibility for particular operations: news desk. 5. a stand used to support sheet music; music stand. —adj. 6. of or pertaining to a writing desk: a desk drawer. 7. made for use on a desk: a desk dictionary. 8. done at or based on a desk: a desk job. [ME deske < ML desc(a) table < L disc(us) desk, dish] + +desk-size (desk/siz'), adj. of a size suitable for use at a desk: a desk-size dictionary. + +desk/top pub/lishing (desk/top'), the writing, assembling, and design of publications, as business reports, newsletters, and trade journals, in a business or editorial office by the use of computers, esp. microcomputers. + +D. ès L., Doctor of Letters. [< F Docteur ès Lettres] + +des-man (des/man), n., pl. -mans. either of two aquatic, insectivorous mammals, Myogale moschata, of southeastern Russia, or M. pyrenaica, of the Pyrenees, related to shrews. [< Sw, short for desman-ratta muskrat] + +des-mid (des/mid), n. any of the microscopic freshwater algae belonging to the family Desmidiaceae. [< NL Desmid(ium) name of the genus < Gk desm(ōs) a band, chain + NL-id-dim. suffix] —des-mid/i-an, adj. + +des-moid (des/moid), adj. Anat., Zool. 1. resembling a fascia or fibrous sheet. 2. resembling a ligament. [< Gk desm(ōs) (see DESMID) + -oid] + +Des Moines (də moin', moinz'), 1. a city in and the capital of Iowa, in the central part, on the Des Moines River. 201,404 (1970). 2. a river flowing SE from SW + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/16c_pg1_pg1_repeat1.md b/outputs/long_tiny_text/16c_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0235ecc6f5f913040b8e5f4a1530ddf2a72e48dd --- /dev/null +++ b/outputs/long_tiny_text/16c_pg1_pg1_repeat1.md @@ -0,0 +1,129 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +a beautiful wedding; a reception after the wedding. Nuptials is a formal and lofty word applied to the ceremony and attendant social events; it does not have emotional connotations but strongly implies surroundings characteristic of wealth, rank, pomp, and grandeur: royal nuptials. + +marriageable (mar/i ja bal), adj. suitable for marriage. —mar/riage-a-bil/i-ty, mar/riage-a-ble-ness, n. + +marriage of convenience, a marriage for some advantage or expediency, esp. one for the sake of money or social position. + +marriage portion, dowry. + +married (mar/ed), adj. 1. united in wedlock; wedded. 2. of or pertaining to marriage or married persons. —n. 3. Usually, marrieds. married people: Young marrieds are prime buyers of furniture. [ME] + +mar-ron (mar/an, ma rôn/; Fr. ma RÔN/), n. a chestnut, esp. as used in cookery: candied or preserved in syrup. [< F] + +mar-rons gla-cés (Fr. ma RÔN/ gla sâ/), chestnuts glazed or coated with sugar eaten as a confection; candied chestnuts. [< F] + +mar-row (mar/ô), n. 1. a soft, fatty, vascular tissue in the interior cavities of bones. 2. the inmost or essential part. 3. strength or vitality. [ME mar(o)we, OE mearg; c. D merg, G Mark, Icel mergr] —mar/row-ish, adj. —mar/-row-less, adj. —mar/row-y, adj. + +mar-row-bone (mar/ô bôn/), n. a bone containing edible marrow. [ME] + +mar-row-fat (mar/ô fat/), n. a large-seeded variety of pea. + +Mar-rue-cos (mär rwe/kôs), n. Spanish name of Morocco. + +mar-ry¹ (mar/ē), v., -ried, -ry-ing. —v.t. 1. to take as a husband or wife; take in marriage. 2. to perform the marriage ceremonies for (two people who wish to be husband and wife); join in wedlock. 3. to give in marriage (often fol. by off). 4. to unite intimately. 5. Naut. a. to lay together (the unlaid strands of two ropes) to be spliced. b. to seize (two ropes) together end to end for use as a single line. c. to seize (parallel ropes) together at intervals. —v.i. 6. to take a husband or wife; wed. [ME marie(n) < OF marie(r) < L maritāre to wed < marīt(us) conjugal, akin to mās male (person)] —mar/ri-er, n. + +mar-ry² (mar/ē), interj. Archaic. (used as an exclamation of surprise, astonishment, etc.) [euphemistic var. of MARY (the Virgin)] + +Mar-ry-at (mar/ē at), n. Frederick, 1792–1848, English naval officer and novelist. + +Mars (märz), n. 1. the ancient Roman god of war, identified with the Greek god Ares. 2. Astron. the planet fourth in order from the sun, having a diameter of 4230 miles, a mean distance from the sun of 142,000,000 miles, a period of revolution of 686.9 days, and two satellites. + +Mar-sa-la (mär sä/la; It. mär sä/lä), n. 1. a seaport in W Sicily. 81,426 (1961). 2. a sweet, dark, fortified wine made near Marsala, or a similar wine made elsewhere. + +marse (märs), n. Southern U.S. (used chiefly in representation of southern Negro speech) master. Also, massa. + +Mar-seil-laise (mär/sə lāz/, -sā ez/; Fr. mar se yez/), n. the French national anthem, written in 1792 by Rouget de Lisle. + +mar-seilles (mär sālz/), n. a thick cotton fabric woven in figures or stripes with an embossed effect, chiefly for bedspreads and other coverings. [alter MARSEILLES] + +Mar-seilles (mär sā/; older mär sālz/), n. French, Marseille (mar se/yə), a seaport in SE France. 783,738 (1962). + +marsh (märsh), n. a tract of low wet land, often treeless and periodically inundated. [ME mershe, OE mer(i)sc (c. G Marsch). See MERE², -ISH¹] —marsh/like/, adj. + +Marsh (märsh), n. Reginald, 1898–1954, U.S. painter and illustrator. + +mar-shal (mär/shəl), n., v., -shaled, -shal-ing or (esp. Brit.) -shalled, -shal-ling. —n. 1. a military officer of the highest rank, as in the French and some other armies. Cf. field marshal. 2. an administrative officer of a U.S. judicial district who performs duties similar to those of a sheriff. 3. a court officer engaged chiefly in serving processes. 4. the police officer in some communities. 5. a higher officer of a royal household or court. 6. a person charged with the arrangement or regulation of ceremonies, parades, etc. —v.t. 7. to arrange in proper order; set out in an orderly manner; arrange clearly: to marshal the facts. 8. to array, as for battle. 9. to usher or lead. [ME, syncopated var. of mareschal < OF < Gmc; cf. OHG marahscalh groom = marah horse (see MARE¹) + scalh servant, c. OE scealc] —mar/shal-cy, mar/shal-ship/, n. —mar/shal-er; esp. Brit., mar/shal-ler, n. —Syn. 7. order; convoke. See gather. + +Mar-shall (mär/shəl), n. 1. George C(at-lett) (kat/lit), 1880–1959, U.S. general and statesman: Secretary of State 1947–49; Nobel peace prize 1953. 2. John, 1755–1835, U.S. jurist and statesman: Chief Justice of the U.S. 1801–35. 3. Thomas Riley, 1854–1925, vice president of the U.S. 1913–21. 4. Thur-good (thûr/gôd), born 1908, associate justice of the U.S. Supreme Court since 1967. + +Mar/shall Is/lands, a group of 24 atolls in the N Pacific: now under U.S. trusteeship. 22,888 (1970); 74 sq. mi. + +Mar/shall Plan/. See European Recovery Program. + +Mar-shal-sea (mär/shəl sē/), n. Brit. Hist. 1. the court of the marshal of the royal household. 2. a debtors' prison in London, abolished 1842. [ME marchalsye. See MARSHAL, -CY] + +marsh/ el/der, U.S. any of various composite plants of the genus Iva, as I. frutescens, which grows in salt marshes. + +marsh/ gas/, a gaseous decomposition product of organic matter, consisting primarily of methane. + +marsh/ hen/, any of various rails or raillike birds. + +marsh-land (märsh/land/), n. a region, area, district, etc., characterized by marshes, swamps, bogs, or the like. [ME mershland, OE merscland] + +marsh/ mal/low, 1. an Old World mallow, Althaea officinalis, having pink flowers, found in marshy places. 2. the rose mallow, Hibiscus Moscheutos. [ME marshmalue, OE merscmealwe] + +marsh-mal-low (märsh/mel/ô, -mal/ô), n. 1. a sweetened paste or confection made from the root of the marsh mallow. 2. a similar confection containing gum arabic or gelatin, sugar, corn syrup, and flavoring. —marsh/mal/low-y, adj. + +marsh/ mar/igold, a yellow-flowered, ranunculaceous plant, Caltha palustris , growing in marshes and meadows; cowslip. + +marsh-y (mär/shē), adj., marsh-i-er, marsh-i-est. 1. soft and wet, as a marsh; boggy. 2. pertaining to a marsh. 3. consisting of or constituting a marsh. [ME mershi] —marsh/i-ness, n. + +mar-si-po-branch (mär/sə pō branᵊk/), adj. 1. belonging to the Marsipobranchii or Cyclostomata , a group or class of vertebrates comprising the cyclostomes. —n. 2. a marsipo-branch fish. [back formation from NL Marsipobranchia a class of vertebrates < Gk mársipo(s) bag, pouch (see MARSUPIUM) + bránchia gills] + +Mars-ton (mär/stən), n. John, c1575–1634, English dramatist and satirical poet. + +Mars/ton Moor/, a former moor in NE England, west of York: Cromwell's defeat of the Royalists 1644. + +mar-su-pi-al (mär sōō/pē əl), adj. 1. pertaining to, resembling, or having a marsupium. 2. of or pertaining to the marsupials. —n. 3. any viviparous, nonplacental mammal of the order Marsupialia , comprising the opossums, kangaroos, wombats, etc., most of which have a marsupium containing the mammary glands and serving as a receptacle for the young. [< NL marsupiāl(is) pertaining to a pouch. See MARSUPIUM, -AL¹] + +mar-su-pi-um (mär sōō/pē əm), n., pl. -pi-a (-pēə). the pouch or fold of skin on the abdomen of a female marsupial. [< NL var. of L marsupium pouch, purse < Gk marsýpion , dim. of mársipos bag, pouch] + +mart (märt), n. 1. marketplace; trading center; trade center. 2. Archaic. a fair. [late ME < MD, var. of markt MARKET] + +Mar-ta-ban (mär/tə bän/), n. Gulf of , an inlet of the Bay of Bengal, in Burma. + +Mar-tel/lo tow/er (mär tel/ô). Fort. a circular, tower-like fort with guns on the top. Also, martel/lo tow/er . Also called martel/lo , Martel/lo . [named after Cape Mortella, Corsica, where a tower of this kind was taken by British forces in 1794] + +mar-ten (mär/tən, -tin), n., pl. -tens, (esp. collectively) -ten. 1. any of several slender, chiefly arboreal carnivores of the genus Martes , found in northern forests, having a long, glossy coat and bushy tail. 2. the fur of such an animal, generally a dark brown. [< MLG = mart marten (c. OE mearth) + -en -EN⁵; r. late ME martren < MF martrine marten fur, n. use of fem. of martrin pertaining to a marten = martre marten (< Gmc; cf. G Marder) + -in -IN¹] + +Mar-tha (mär/thə), n. the sister of Mary and Lazarus. Luke 10:38–42; John 11:1–44. + +Mar/tha's Vine/yard, an island off SE Massachusetts: summer resort. 108³⁄₄ sq. mi. + +Mar-tí (mär tē/), n. Jo-sé (hô se/), 1853–1895, Cuban patriot and writer. + +martial (mär/shəl), adj. 1. inclined or disposed to war; warlike; brave. 2. pertaining to or appropriate for war: martial music. 3. characteristic of or befitting a warrior: a martial stride. 4. pertaining to or connected with the army or navy. [ME < L Martiāl(is) of, belonging to Mars = Marti- (s. of Mars) + -ālis -AL¹] —mar/tial-ism, n. —mar/tial-ist, n. —mar/tial-ly, adv. —mar/tial-ness, n. —Syn. 2. 3. military, soldierly. + +Martial (mär/shəl), n. (Marcus Valerius Martialis) A.D. 43?–104?, Roman poet and epigrammatist, born in Spain. + +martial law/, the law imposed upon an area by military forces when civil authority has broken down. + +Martian (mär/shən), adj. 1. pertaining to the planet Mars. —n. 2. a supposed inhabitant of the planet Mars. [< L Marti(us) of, belonging to Mars] + +mar-tin (mär/tən, -tin), n. any of several swallows. Cf. purple martin . [named after St. MARTIN of Tours, supposedly because it migrates south at Martinmas or thereafter] + +Mar-tin (mär/tən, -tin), n. 1. Glenn Luther, 1886–1955, U.S. airplane designer and manufacturer. 2. Homer Dodge, 1836–97, U.S. painter. 3. Joseph W(illiam) Jr., 1884–1968, U.S. political leader and publisher: Speaker of the House 1947–49, 1953–55. 4. Saint, A.D. 316?–397, French prelate: bishop of Tours 370?–397. + +Martin I, Saint, died A.D. 655, Italian ecclesiastic: pope 649–655. + +Martin II. See Marinus I. + +Martin III. See Marinus II. + +Martin IV, (Simon de Brie or Simon de Brion) c1210–85, French ecclesiastic: pope 1281–85. + +Martin V, (Oddone Colonna) 1368–1431, Italian ecclesiastic: pope 1417–31. + +Mar-tin du Gard (mar tan/ dy gar/), Ro-ger (rô-zhā/), 1881–1958, French novelist: Nobel prize 1937. + +Mar-ti-neau (mär/ti nō/, -tənō/), n. 1. Harriet, 1802–1876, English novelist and economist. 2. her brother, James , 1805–1900, English theologian and philosopher. + +mar-ti-net (mär/tənet/, mär/tənet/), n. a strict disciplinarian, esp. a military one. [named after General Jean Martinet (d. 1672), French inventor of a system of drill] —mar/ti-net/ish, adj. —mar/ti-net/ism, n. + +mar-tin-gale (mär/tən gāl/), n. 1. Also called standing martingale . part of the tack or harness of a horse, consisting of a strap that fastens to the girth, passes between the forelegs and through a loop in the neckstrap or hame, and fastens to the noseband: used to steady or hold down the horse's head. 2. Also called running martingale . a similar device that divides at the chest into two branches, each ending in a ring through which the reins pass. 3. Naut. a. a stay from the end of a jib boom or spike bowsprit to some part of a martingale boom. b. See martingale boom . 4. any of a number of systems of gambling in which the stakes are doubled or otherwise raised after each loss. [< MF < ?] + +Marten, Martes americana (Total length about 2½ ft.; tail 9 in.) + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/17_pg17_pg1_pg1_repeat1.md b/outputs/long_tiny_text/17_pg17_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..054ecaaa080dea4172596c9700642fa2af825b71 --- /dev/null +++ b/outputs/long_tiny_text/17_pg17_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +impartially dealt with, we had no just claim against the Nizam.† In 1853,† he repeats 'we had little or no claim against the Nizam.'‡ In 1853 there was, in fact, a disputed balance-sheet. The balance of 430,000, which was demanded was made out by debiting the Nizam with cash payments from our Treasury for the Hyderabad Contingent, while refusing to credit him with sums due to him by our Government on other accounts. Interest, first at 12 and afterwards at 6 per cent., on all our advances, formed nearly a quarter of the claim. The principal of the Nizam's counter-claim, without any calculation of interest, was more than the whole charge against him. But no set-off, or inquiry as to a set-off, was tolerated by Lord Dalhousie's Administration; though subsequently, under Lord Canning's Government, the chief item—the abkaree, or excise collections of Secunderabad and Jaulah—was prospectively allowed to be a portion of the legitimate revenue of the Hyderabad State. + +No plea of set-off was listened to, and a distress was put in, embittered by terms of menace and insult. Lord Dalhousie, in the process of enforcing this most questionable pecuniary claim—most questionable even if the Nizam's large counter-claims were excluded—had written personally to the Nizam, telling him that the Hyderabad State was bound to maintain the Contingent 'by the stipulations of existing treaties;' reminding him that it was dangerous 'to provoke the resentment of the British Government,' 'whose power can crush you at its will,' § and warning him that 'the independence of his sovereignty' stood in imminent danger.' In the same letter the Nizam was advised, as an indispensable measure of economy, to disband 'the Arab soldiery; those 'turbulent mercenaries' who consumed so large a portion of his revenues, and to rouse himself to make a great effort for 'the early liquidation of the accumulated debt.' If the Nizam were unable to meet the call on his treasury, he must 'forthwith make over' to the British Government certain frontier districts of his territory enumerated in a schedule annexed to this letter.¶ + +It was a ready money question entirely. In 1851, when the unpleasant letter from which I have quoted was addressed to him, the Nizam stayed off the difficulty by paying a large sum on account. If he had produced the cash that 'was demanded in 1853; when similar pressure was applied, he would have avoided the sequestration of his districts. But his resources and his credit were exhausted, and the Governor-General would wait no longer. The Nizam's vain endeavours to gain time were cut short by an intimation that unless he at once consented to sign the new treaty, orders would be given for the advance of British troops, not merely into the districts that were wanted, but also into his capital. Then the Nizam and his advisers saw that he had before him the choice of signing the treaty + +or being dethroned. They understood perfectly, if every one else was ignorant of it—which is not likely—that it must come to that. The Nizam's Government was not as strong in 1853, nor was Hyderabad as orderly, as they have become during the treaty years' administration of the Nawab Salar Jung. Without counting the armed men in a fortified city of 200,000 inhabitants, were almost every man was armed, Hyderabad was full of those turbulent mercenaries whom our Government, as they, of course, were well aware, was urging the Nizam to disband. They knew that military occupation meant not only the loss of their bread, but the loss of their hard-earned savings. For the Arab soldiery were the greatest money-lenders in Hyderabad, and after their expulsion by British power they would obviously have had great difficulty in collecting their little accounts. Their leaders would certainly have taken every advantage of Mussulman fanaticism and general excitement to have one last desparing struggle before they submitted to the loss of their homes, and of all that they possessed. Although the city could not have resisted a British force for six hours, it would not have been occupied without a contest. But the first shot fired from the walls, the first drop of blood shed, would in those days, so far as we can argue from the general tone and temper of Lord Dalhousie's administration, have cost the Nizam his throne. It would certainly have been worse than useless for him to plead that he could not control the unruly rabble of his capital. If, as might easily have been the case, a great number of the combatants had been proved to be in his own pay, his conduct would have been stigmatized as gross and infamous treachery. It would have gone hard with him. + +We have seen Lord Dalhousie representing to the Nizam that the Hyderabad State was bound to maintain the Contingent 'by the stipulations of existing treaties,' and I have said that this representation was erroneous. That it was so I shall prove from Lord Dalhousie's own mouth, and this will afford a very striking illustration of the inquisitive manner in which the actual system of secret correspondence and consultation effects the weaker party. In 1851 the Governor-General insists that 'the efficient maintenance of the Force is a duty imposed on the Government of Hyderabad by the stipulations of existing treaties,' and again, that it is 'necessary to fulfil the obligation of treaties.' In 1853—having in the meanwhile, we may suppose, examined more carefully the documents bearing on the case—he arrived at a very different result. 'I have found myself forced,' he says, to the 'conclusion that the Government of India has no right whatever, either by the spirit or by the letter of the Treaty of 1800, to require the Nizam to maintain the Contingent in its present form.' And again, in the same minute he says: 'I, for my part, can never consent, as an honest + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/17_pg24_pg1_pg1_repeat1.md b/outputs/long_tiny_text/17_pg24_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2eb2f78a72523c7e2102f0d881d0b90da467b926 --- /dev/null +++ b/outputs/long_tiny_text/17_pg24_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +date, still open to reparation, that positively bristle with blunders as to facts, dates and circumstances, proved or disproved by recorded testimony. + +No observant person can be blind to the prospect before us of a progressive increase in the number of political complications in India, and of appeals to the Home authorities from Princes and Chieftains. The enhanced facilities for locomotion throughout the Peninsula, and for communication with Europe, and the more general employment of highly-enduced Indians, have let in a flood of light upon the Native States, and have rendered it more and more difficult to stifle inquiry or to silence remonstrances. The whole course of events ever since the great crisis of 1857, down to the visit of the Prince of Wales, with its many gracious and gratifying incidents, has raised the self-respect of the Indian Princes, and has made them feel a sense of greater security. At the same time, they cannot fail to perceive and to understand that their improved position has been due, from the first till now, to the policy and compulsion of the Home authorities, and not to any sudden conversion of the Vice-regal Foreign Department and its functionaries. They know, for example, that the two most noble reversals of annexation, the maintenance of the Mysore State and the restoration of of Dhar, were carried out by Her Majesty's Ministry in spite of the strenuous and persistent opposition of the Governor-General in Council. They feel themselves more safe now than they ever were before, so long as they are convinced that the Imperial Government is watching over them, but they have had little or no reason to acquire greater confidence in the kindness and candid consideration of the Department with which they are in immediate contact. The old supercilious domination, the secret and arbitrary conduct of business, as of old, still prevail; the only change is that the Princes have learned to chase under them. They have outgrown the present system; it will not work smoothly much longer. The absence of any visible and conclusive process, the consciousness of one's case not having been answered, are strong provocatives to contumacy and passive resistance. Until on open tribunal is established, there will be no safety-valve or self-adjusting appliance to prevent a dead-lock from occurring at any time a dead-lock that could only be broken through by sheer force of arms. + +No maintain a moral as well as a martial supremacy, to elevate the standard of executive procedure in accordance with the requirements of the age, the Foreign must be transformed into the Federal Department, and there must be a judicial check over all acts of state that are beyond the control of the ordinary courts. The question is, where this check is to be placed, and how it is to be exercised. + +Whenever the subject has hitherto been discussed there has been a very general declaration that if provision can be made for a fair hearing + +and for the delivery of a judgment on the merits according to the evidence in such cases as are referred for consideration, the designation and constitution of the Court,—whether it is to be a Committee of the Privy Council, or of the Indian Council, or, as recommended by Mr. McCullagh Torrens and Mr., E. B. Eastwick a Joint Select Committee of both Houses of Parliament,—are matters of secondary importance. + +Although distinctly desirous that a strong legal element should prevail, I should place much more reliance on the influence of free advocacy and open judgements than on the presence of transcendent judicial ability in any tribunal that may be established. It is the Bar that makes the Bench, and that keeps it up to the mark. The necessity of confronting public inspection and criticism, especially that of exerts, is one of the most salutary incentives to patience, caution, and care in forming and promulgating a judgment. + +My own preference is for the old constitutional authority of Her Majesty's Privy Council, not by merely resorting to the Judicial Committee, but by an extension on the old lines, and in conformity with historical precedents, of the functions of that august body. There is a great want, quite recently acknowledged, as we shall see, by those who have some right to speak, of more potent consultative assistance for the Imperial Executive at both ends of the Suez Canal, in London and in Calcutta. Both the Viceroy and the Secretary of State are at present induced, by a certain want of weight in their respective Councils, to rely much more on their own autocratic power than can always be prudent or safe, or good for the public interests. Here what was said a few days ago by one who has been Secretary of State for India. On the 31st of March last the Duke of Argyll begged the House of Lords "to remember what was the power of the Secretary of State for India. No other Minister in the country exercised a tenth part of the power which could be exercised by the Secretary of State for India. That Secretary held in his own hands all the powers which formerly were vested in the Court of Directors and in the Board of control, acting through the Secret Committee. That was, he held in his own hands the entire power of the Imperial Government of India. The only direct check which existed on that power was that he could not give money grants out of the revenues of India without the assent of a majority of the Council. But the Secretary of State might, of his own act, and without the assent of a majority of the Council. But the Secretary of State might, of his own act, and without the assent of any one, order to be undertaken, and might direct measures which would involve an expenditure of millions, and lead to great financial embarrassment. The only other check was the Imperial Cabinet; but it was impossible for the other members of the Cabinet, engaged as they were with heavy business in their own Departments, to + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/17_pg2_pg1_pg1_repeat1.md b/outputs/long_tiny_text/17_pg2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..eea954a0275182de0ae5ce630aef37013efb7ec6 --- /dev/null +++ b/outputs/long_tiny_text/17_pg2_pg1_pg1_repeat1.md @@ -0,0 +1,9 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +of the multitude at home unless his name happens to be associated with some Imperial measure, in which case he is seldom favourably mentioned. As long as he is engaged in the Government of some Native State, improving its condition, directing its internal economy, and regulating its finances, he is only known to the Indian Government and its servants, and he is generally all the better for his obscurity. But from the time that Poornachal won the admiration of one of the ablest of our own statesmen down to the present moment, the Native States of Hindostan have rarely failed to produce administrators of marked ability. The visit of the Prince of Wales has produced many results which were not foreseen by the most sagacious observers at home or abroad. It is likely to leave an indelible mark on the history of the relations between England and India. Had that tour never been undertaken Sir Salar Jung would, in all probability, have come to England; but he would have appeared among us in different, and, in all likelihood, in less agreeable, circumstances. Eminent as his services have been, and remarkable as his career has been, there are many thousands who ask, "Who is Sir Salar Jung?". And there are many thousands who have never heard of his name. It was a revelation to millions, indeed, to hear that there were still Native States in India with Courts, Ministers, and Armies of their own. We fear that there are some, even among the educated classes, who would be puzzled to give a very definite account of the Deccan, or to describe the territories of the Nizam, and the nature and relations of the State and its ruler with the British Government. Had the Deccan been involved in the troubles of 1857-8, as Gwalior and Indore were, we should, no doubt, have acquainted with the particulars, but the services which were rendered to the British Government at that eventful period were of the utmost value and magnitude, although they, fortunately, did not need to be written in characters of blood. The Deccan extends over nearly 100,000 square miles, and is peopled by 10,000,000 inhabitants, of whom the vast majority—probably nine in ten—are Hindoos. The soil is generally good and produces cotton in abundance. Coal and iron mines have been discovered, and the great rivers Kistna, Tombuda, and Godavery drain the vast plateau which forms the bulk of the land and open it to the Eastern and Western Oceans. The first Nizam established friendly relations with the English Governor of Fort St. David in 1747, which were generally maintained in the wars with the French and their allies, and, although for a time the ability and genius of Bussy secured the ascendancy of his councils and influence at Hyderabad, the troops and resources of the Nizam were placed at our disposal in the campaign against Tippoo in 1791, and in the struggle with the Mahrattas, and the alliance has continued to the present day. In 1853 Sir Salar Jung was + +appointed to succeed his uncle, Suraj-ool-Moolk, as Dewan to Nasir-ud-Dowla, who had just been forced by Lord Dalhousie to assign to the superintendence of the British certain rich districts to secure the payment of debts alleged to be due for the pay of the Contingent which was kept up in accordance with the Treaty by the Dewan. He was only 19 years of age, and the condition of the State was one which might have appalled the boldest and most experienced of statesmen. + +There was no money in the Treasury—the system of taxation was wasteful and unproductive. Although the Residents at the Court of Hyderabad had been for many years possessed of paramount power, they applied their energies to the sole object of securing British interests, and did not interfere in the internal affairs of the State with a view to its improvement. In fact, as long as the enormously expensive Contingent was paid, they cared little for the manner in which the money was raised. Armed bands, miscalled soldiery, carried terror and dismay through the country, and created, disturbances and riots in the towns at their pleasure. Hyderabad was a hot-bed of turbulent fanaticism. Arab mercenaries and Rohillas, ever ready for mischief, paralyzed the arm of law and order, blighted trade and commerce, and threatened at any moment to require the attention of the Governor-General, at that moment Lord Dalhousie, whose methods in such cases were terribly earnest. Salar Jung began his work by refusing to draw more than half the salary of his office, and his example was followed by the other servants of the State. He put an end to the system of forming the revenues; he discouraged the immigration of Arabs and Rohillas, and set to work to strengthen the hands of the police, and to obtain some degree of security for property and life. But while he was engaged in this Herculean task there came upon him a trial, the tension and force of which can never be understood by a European and a Christian. He was a Mahomedan, and he served a Mahomedan State. The Power which had destroyed the rule of Mahomedan and Hindoo alike was in the utmost peril. The Mutiny and Rebellion had spread over India, and the Governor of Bombay probably told no more than the truth when he telegraphed to the Resident at Hyderabad—"If the Nizam goes all is lost." But the Nizam did not go. Salar Jung, surrounded by armed crowds, who threatened and reviled him, held fast to the British Government. He held the control with a masterly hand, arrested and delivered over to punishment the rioters who attacked the Residency, and inspired the Resident with such a conviction of his ascendancy and fidelity that he ordered the Hyderabad Contingent to join the British forces, with whom it rendered the most signal services. It would be foolish to pretend that in his efforts he had the sympathy of the Mahomedan populace, and that + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/17_pg33_pg1_pg1_repeat1.md b/outputs/long_tiny_text/17_pg33_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c8ccdedfb1427c6ecf2d362e905adb86806d1b1d --- /dev/null +++ b/outputs/long_tiny_text/17_pg33_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +back on the chances of native rule,—not because any honorable consideration really claims the sacrifice, but merely because a distinguished foreigner of newspaper writers in London,—is in fact altogether too preposterous to be discussed in an entirely patient tone. + +PIONEER 1st July 1876. + +SIR SALAR JUNG. + +An unfortunate accident has detained Sir Salar Jung at Paris beyond the time when he was expected to arrive in London; but when he comes he will meet with the reception he deserves from all who know how immense are the services he has rendered to England. He has made the power of the Nizam of a cordial instead of a doubtful ally; he did more, perhaps, than any other man to help England in the crisis of the Mutiny; and he has set a brilliant example of what may be done in a protected State when the State is administered in accordance with English ideas. For a century the history of the Nizams of Hyderabad has been the history of princes who have been forced into an alliance which they have very much disliked, and by which they have very much profited. They were inclined to an alliance with the French, and we made them abandon that alliance. They sided with Hyder Ali, and we made them change sides and come over to us. They disliked fighting Tippoo, and we made them fight Tippoo. They were driven by a perverse good fortune into being always on the conquering side, they were paid handsomely for choosing the lucky cause against their will, and the present infant prince owes a large part of his territories to the munificence of a Government which shared the spoils of its victories with his predecessors. In the internal concerns of Hyderabad the British Government has interfered from time to time, being always desirous that the military power should be completely under British control, and occasionally shocked at glaring instances of misgovernment and oppression. After the fall of the French power in India, the Nizam of the day got together a small army, well drilled and organized and commanded by Raymond, one of the most brilliant of the French adventurers of his day. Lord Wellesley thought this far too dangerous a weapon in the hands of an ally whom he thoroughly distrusted. He insisted that the French officers should be sent away and the troops they had trained disbanded; and this was effected nominally by the orders of the Nizam, but really by the troops being forced to submit when they found English guns in command of their cantonments. Soon after an arrangement was effected which, with slight changes, has lasted to the present day. The Nizam handed over a portion + +of his territory to be administered by the British Government, who undertook out of the revenues to provide a safe little army for him. The last treaty on this head was made in 1853; but the territories then ceded for that purpose made such rapid progress under British rule that the revenue was much in excess of what was needed to support the contingent. Accordingly, Lord Dalhousie gave back a part of the ceded territory, and Lord Canning gave back all of it, except Berar. It is reported that to get Berar also is one of the aims of Sir Salar Jung in his present visit to England. The excuse for requiring territory was that the affairs of the Nizam were so badly managed that the British Government, without a material guarantee, could not be sure of getting enough to support the contingent it undertook to provide; and now that Sir Salar Jung has put the revenues of the Nizam into a state of great prosperity, he no unnaturally thinks that the British Government does not need any territory as a guarantee for payment. The use made of the contingent gave rise to the only direct act of interference on a large scale in the administration of the internal affairs of the Nizam to which the superior Power has found itself driven. The revenue of several districts which had been farmed to middlemen; oppression was extreme, and British officers had to be employed in putting down the resistance of despair. To avoid the scandal, Sir Charles Metcalfe was sent as Resident, and he established a land settlement which gave peace and property to the country, and has subsequently had the advantage of teaching capable natives, like Sir Salar Jung, what is the meaning and what are the conditions of good government. + +The lesson set by Sir Charles Metcalfe in 1820 survived only in the memory and traditions of a few when, in 1853, Sir Salar Jung was called as a lad of nineteen to fill the post, previously occupied by his uncle, of chief adviser to the Nizam. He found everything in confusion; the system of farming the revenue had again been introduced, and payment was enforced by the employment of mercenaries who sucked the life-blood out of the people. Sir Salar Jung set himself with unflinching resolution to bring in a new state of things, and he had already done much when the terrible crisis of the Mutiny came to try his courage, and to give him the opportunity of deciding the momentous question whether the great Mahometan State of Hyderabad should side with or against the insurgents. If Hyderabad revolted, it was beyond doubt that all Southern India would revolt too; and when Delhi fell the Governor of Bombay telegraphed to the Resident of Hyderabad that if the Nizam went, all was over. But the Nizam remained faithful, and that he so remained, in opposition to the earnest wishes of a powerful body of his subjects, was due to Sir Salar Jung, General Hill, who, as having commanded the Hyderabad Contingent, + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/17_pg34_pg1_pg1_repeat1.md b/outputs/long_tiny_text/17_pg34_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f1a2bfd2246dd36e1b711f94f3c39dc6a4f77db7 --- /dev/null +++ b/outputs/long_tiny_text/17_pg34_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +well acquainted with the facts has stated, in his interesting letter to the Times, that when the Resident informed Sir Salar Jung of the fall of Delhi he was told that the news had been already known three days in Hyderabad, and if Sir Salar Jung had ever thought of seizing an opportunity to desert the English Government, he had ample means of using his earlier information for the purpose. But he never wavered. He had made up his mind that the cause of England was the cause of good government. He knew that the success of the rebellion would only make universal the state of things from which he had been for four years endeavouring to rescue the territories of his master. Those who surrounded him took a very different view, and could not bear to throw away a golden occasion of winning a triumph for their religion, and letting plunder and oppression run riot. He was exposed to constant menaces and much danger, but he showed himself thoroughly equal to the task he had undertaken. When the Residency was attacked, he saved the lives of those who were threatened. He stationed Arabs on whom he could depend at the gates of Hyderabad, and bade them shoot any one who incited the people to revolt against the English. He had such control over the Hyderabad Contingent that the English Government found it safe to employ it, and derived considerable benefit from its services. In a word, our new guest is the man who, when Delhi had fallen and our power was for the moment tottering in the balance, saved Southern India for England. Even if Southern India had revolted. It is possible that by a profuse expenditure of men and money we might have conquered it back again and all the rest of India as well. But Sir Salar Jung spared us the expenditure of countless lives and countless millions; and if ever there was a clear occasion for acknowledging in a fitting manner an inestimable service, such an occasion is presented by the arrival in England of the prime Minister of the Nizam. + +Sir Salar Jung has rendered a less striking, but still very considerable service to England by his administration of the dominions of the Nizam in recent years. He has made good order everywhere prevail. Roads, tanks, wells, irrigation works a good police and schools, are among the benefits he has conferred on his country; and gradually he has achieved the most difficult success of all, and has made his fellow-natives see that he has been throughout in the right, and that in the pursuance of the policy which he started lie all their best hopes for the future. Naturally, like every one who tries to do good in a semi-barbarous country, he has provoked bitter personal hostility; and in 1868 an attempt was made to assassinate him. But the attempt only brought into relief the estimation in which he was generally held; and his escape was welcomed with delight by people of all classes. Nor is it only that he has made the Deccan one of the most + +flourishing parts of India. He has helped us to solve the difficult problem of how we are to treat the independent principalities of which we have lately heard so much. Mr. Hunter records, in his Life of Lord Mayo, the anxiety which this problem caused to the new Governor-General. He determined that from the outset of his rule he would deal with the independent princes on fixed and definite principles. After long consideration Lord Mayo came to the conclusion that there were three principles on which the Government ought consistently and resolutely to act. The first of these was non-annexation, the misrule of a native chief not being used as a weapon for aggrandizing the power of England. The second was that the Government should always acknowledge its responsibility for any serious misrule in a Native State, and should be ready to interfere by displacing the offending chief, and administering the territory through British officers, or a native regency, in the interest of the lawful heir. The third principle was that all those who ruled well should be in every way honored and encouraged. Lord Mayo had the strongest possible sense of the personal side of government, and he laid down as one of the duties of a Viceroy that he should be the friend and not merely the patron of good men. The English were to do their best to govern well in their own dominions, not only directly for the sake of those they governed but indirectly for the sake of those governed by native chiefs. When it was seen that an honest endeavour was being made in a Native State to copy the pattern set by England, then the highest honors were to be offered and the most cordial friendship was to be shown to those who had been paying England the most welcome of tributes—the tribute of imitation. The one road to favour was to lie through good works. What Lord Mayo wished to see done for the improvement of all Native States has been done in the simplest manner by Sir Salar Jung for the territories of the Nizam. He has abundantly earned the respect, the friendship, and the honor which Lord Mayo proposed should be the reward of the wise administration of the Native States; and Englishman, who give Sir Salar Jung the reception he has merited, will have the satisfaction of at once welcoming a benefactor and of knowing that they are helping to carry out a leading principle of Imperial policy.—Saturday Review. + +THE MAIL, 3rd July 1876. + +Sir Salar Jung had an interview with the Queen at Windsor, on Thursday, and joined the Royal dinner party in the evening. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/17_pg4_pg1_pg1_repeat1.md b/outputs/long_tiny_text/17_pg4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f10fe51f13535bb8f1e56fd341fd396896c1a0bf --- /dev/null +++ b/outputs/long_tiny_text/17_pg4_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +he found a telegram from Lord Canning informing him that Delhi had fallen into the hands of the mutineers, upon which he sent for Salar Jung and communicated the intelligence to him. Salar Jung replied, "This was known in the city three days ago." + +Here, then, was an undoubted proof of the loyalty of the Nizam's Government, for, had there been any disposition to upset the British rule in favour of the Mahomedan Power, there could not have been a more fitting opportunity for doing so than when all the English officers were collected in the Nizam's Palace, surrounded by his armed retainers and entirely in their power. + +Later on, when the spirit of disaffection was at its height and had reached the city of Hyderabad, the wisdom and determination of Salar Jung were eminently shown by his ordering all the Arabs who were the principal land proprietors in the Hyderabad territory to repair at once to the city, and by placing large bodies of these brave and fearless men at each of the principal gates, with orders to fire upon any one who attempted to invite the people to rise against the English. + +These energetic measures saved South India, for had the people of Hyderabad risen against us, the Mahomedan population of Madras would, it was well known at the Presidency, have followed their example; and it is but just to this distinguished man that the people of England should be informed how entirely the stability of British rule in South India was owing to the wise and energetic measures adopted at this crisis by Salar Jung. + +Having held the chief military command in His Highness the Nizam's dominions for some years, and having been consequently brought into constant communication with the Resident during that momentous period, I feel a real pleasure in giving publicity to the facts above stated, being assured that Sir Salar Jung will receive from the British public that warm and-friendly welcome which he so eminently deserves from our countrymen. + +I am, Sir, your obedient servant, +WILLIAM HILL, Major-General, R.C.S.I. +late Commanding, Hyderabad, Contingent. + +THE WORLD, 31st May 1876. + +SIR SALAR JUNG'S MISSION. + +It is no secret that the visit of Sir Salar Jung to England is connected with the question of the Berars. Why that visit is necessary is not a pleasant story to tell; for in all the history of our dealings with the native + +princes of India, there is not one page more dark, more disgraceful, more humiliating than that which tells of our relations with the Nizam. Our statement is founded solely on official documents, on treaties, and on the letters of the highest officials in India, the great majority of which have appeared in bluebooks. + +The Berars, the richest provinces of the Nizam, came into the possession of the British, by virtue of a treaty in the year 1853, as a security for the payment of the force known as the Hyderabad contingent. This treaty was supplemented by another in 1860, which altered some of the relations in which the contracting parties stood to each other. The contention of the Nizam is, that this treaty of 1853 was unjustly forced upon him in defiance of right and of the treaty of 1800, which had up to that time governed the relations between the two countries; and the demands that the treaties of 1853 and 1860 should therefore be cancelled, and that he should revert to the treaty of 1800. + +A few words will explain the relations between the two powers prior to the treaty of 1800. The Government of the Nizam had, from its earliest contact with us—that is to say, in 1747—been friendly to the British power in India. It had early sided with us in our struggle with the French, and, with one or two exceptions, the friendly connection had remained unbroken. The end of the century saw us bound together by common interests against common foes. Tippoo at Seringapatam and the Mahrattas on the Deccan threatened both powers alike, and the treaty, offensive and defensive, of 1798 testified to the closeness of the bond. Two years later the treaty of 1800 drew the tie still closer; for by it the British Government guaranteed absolutely the integrity of the Nizam's dominions against all comers, while the Nizam on his part ceded to England in perpetuity a large portion of his territories—one-third, indeed, of the whole—the revenue to be derived therefrom to be devoted to the maintenance of a subsidiary force, which was fixed at 8000 infantry and 1000 cavalry, with the requisite complement of guns. An article was inserted specifying expressly that no further demand should ever be made by the British on behalf of this force. This subsidiary force was by the terms of the treaty to be stationed in time of peace in the Nizam's dominion, and was to be at his disposal to put down insurrection and restrain the feudal Rajahs. The English pledged themselves to abstain from all interference of any kind in the internal affairs of the Nizam's dominion. In case the two powers should take the field together against a common foe, the Nizam agreed to put 6000 infantry and 9000 horse with artillery in the field, and further to use every effort to bring the whole force of his kingdom into the field. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/17_pg86_pg1_pg1_repeat1.md b/outputs/long_tiny_text/17_pg86_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5150134d636200e4c4240ee04022c4de05b3203f --- /dev/null +++ b/outputs/long_tiny_text/17_pg86_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Association desired to give every facility to all views elucidatory of the wants of India and of its people, and in doing so they believed they were forwarding the best interests of the English administration. He cordially agreed with the remarks of the chairman regarding Sir Salar Jung, and he looked for much permanent advantage to the visits of chief and rulers of India to England; for the closer the intimacy of the two peoples the more real and abiding would be their respect for each other, and hence the more conducive to the permanency of the English Empire in the East. + +Colonel Rathborne seconded the resolution, which was agreed to *nem con.* + +The Chairman, in proposing the re-election of the Right Hon'ble Sir Lawrence Peel as president for the ensuing year, said he thought it a great advantage to the Association that they had a gentleman for their president who was not only distinguished for his acquaintance with his own profession, and India, but who was equally well known as a man of moderation, who was acceptable to all parties, a man in whose judgment confidence could safely be proposed, a man who, while of strong feelings, never allowed them to mislead him into errors of judgment. He therefore had very sincere pleasure in moving his re-election. + +Mr. John Dickinson seconded this, and said that Sir Lawrence Peel was a man of high reputation not only in the profession but in the country generally, and it was a great advantage to the East India Association to have such a man at its head. The resolution was then agreed to *nem con.* + +General Burn proposed that the following gentlemen be re-elected members of the Council:—Major Evans Bell, W. S. FitzWilliam Esqr. Colonel P.T. French, Captain W. C. Palmer, Surajal M. Pundit Esqr., Colonel Rathborne, P.M. Dait, Esqr., and W. Tayler, Esqr. These gentlemen, he said, were well known to the Association, and that was their best title to re-election. + +General Sir George Malcolm seconded the resolution, which was agreed to *nem con.* + +Colonel Rathborne said that as this concluded the formal business before the meeting, he would venture to introduce another subject, and that was that as they would soon be obliged to vacate their present promises, it would be very desirable to consider the advisability of leasing or creating a hall sufficiently roomy to accommodate the members as readers or visitors; and their growing library; and further to allow of the delivery of lectures on subjects of Indian interest. This hall could be made the centre of lecturing all over the country, and especially when any occasion made an Indian topic of special and sudden interest, as was not unfrequently the case. + +Mr. Dickinson said that while there could be little question of the advantage of having such a hall, the first and the main difficulty was how to raise the money. To build a hall of any size in that part of London would require a very large sum. + +After some further conversation on the details of such a scheme, the suggestion was referred to the Council for consideration. + +General Burn asked whether the Council had taken any action yet on the subject of the depreciation of silver? This was a question of the most vital interest to thousands of Englishmen, for it involved an income tax of at least 25 per cent. He did not profess to be able to offer any suggestions on a subject upon which even experts greatly differed, but one had recently been made which seemed reasonable as likely to retard the depreciation of the rupee, and that was to assimilate it and make its circulation indiscriminate with the English florin. + +The Chairman said the production of the silver mines of America as such an indefinite factor in the calculation that there was really no telling where the depreciation would stop. He could say that the Government were considering the matter in every possible light, but the subject was one of extreme difficulty. + +Mr. Dickinson said an impression prevailed that strong pressure was being put upon the Marquis of Salisbury to introduce a double coinage. The subject was not one which would admit of experiments: any crude measure would be extremely dangerous. As to forcing a gold currency upon India, he could only say its use would be quite a novelty. Gold used in India was regarded as a mercantile product and not as a coinage. It was a curious fact that out of the whole population of the globe only a very small proportion use a gold standard coinage,—at present only Germany and England. A suggestion has been made that England should head a league for the demonetization of gold or put ourselves at the head of a silver-using league. The subject was of pressing importance, for the depreciation involves frightful loss to everybody connected with India. + +Colonel Rathborne said he had given some attention to this subject. In 1851, when at Hyderabad, he had charge of the gold taken in the fort there; and it was for sale. Hearing of the gold discoveries in Australia, he foresaw a fall in the price in the market, and urged immediate sale. But the Government hesitated and delayed for two years, and the result was the loss he had foreseen. This circumstance turned his attention to the subject of the currency, and he took up the opinion that it was quite impossible for India to have a different currency from England. Gold, by the way, he might remind Mr. Dickinson, had been in use as a coinage in India; and in Aurungzebe's time it was as much used for this purpose as + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/20_pg18_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg18_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7a11a4cc1350f7ee2d4633790e95f36ea8125bb3 --- /dev/null +++ b/outputs/long_tiny_text/20_pg18_pg1_pg1_repeat1.md @@ -0,0 +1,169 @@ +# @ + +# Your View + +![](figure) + +###### TWEETS AND EMAILS + +![](figure) + +![](figure) + +###### ARTS + +###### IN MO + +![](figure) + +###### A question of governance + +A desire to be governed by our elected politicians rather than faceless Eurocrats has been cited as one of the main reasons for leaving the EU. We have the chief Brexiteers, who disappeared when the going got tough, the Prime Minister, who has little support for her one possible solution and Jeremy Corbyn – a man who does not seem to be able to mount a credible opposition. Throughout the negotiations, the EU has run rings round our representatives. Who would we prefer to be governed by? + +## GERRY RADFORD + +CAMBRIDGE + +###### Language on the move + +I’m afraid that Neil Cairns (Your View, + +## 3 January) is mistaken + +in his interpretation of English words. In the UK, “stations”are where passengers wait for their trains, buses and trams; a “depot”is where buses are parked and serviced, while a “shed”is where trams and railway locomotives are parked. + +## DAVID R WILLIAMS + +LLANDUDNO, CONWY + +I agree entirely with Ken Smith and Neil Cairns’ comments about the misuse of English words. The most annoying phrase I hear is “See you later”when parting from temporary company, especially when there is no chance of the speaker and oneself ever meeting “later”! It may seem friendly but it is a pointless remark. One other word which is, to me, disrespectful is the word “cops”instead of police. + +## DAVID CULM + +LITTLEOVER, DERBYSHIRE + +Can I briefly add two more Americanisms + +###### AY’S + +Sheila Atim, the Olivier-winning star of Bob Dylan musical ‘Girl from the North Country’, on her new musical + +![](figure) + +## that I have noticed a lot lately: “rookie”and “zero-sum-game”? ROBERT BOSTON KINGS HILL, KENT + +My two least + +favourite examples of Americanisms are “from the get-go”in place of the simpler “from the start”, and worst of all “stepping up to the plate”, a baseball-related term. We are a cricketing nation – we “step up to the crease” surely? + +## DAVID DAY + +ANDOVER, HAMPSHIRE + +It’s not an Americanism (or is it?) but can someone explain the term “hike”as in “rail fare hike”? Is it different in some way to “rail fare increase”? It’s beginning to be irritating. + +## KATHY WEBSTER + +LEAMINGTON SPA, WARWICKSHIRE + +Could I ask why the word “cupcake”appears to have replaced “bun”? “Bun”is shorter than “cake”, thus signifying the fact that buns are smaller than cakes, whereas “cupcake” is almost twice as big and has no logical connection with cups. + +## T J HONEYBONE + +DONCASTER, YORKSHIRE + +###### Translator required + +Reading Chris Green’s run-down of Scots’ phrases (i, 2 January) reminded me very much of the first time I took my English wife to meet with my relatives in Stonehaven, near Aberdeen. She found it very disorientating since she could hardly follow any conversation. She expressed some surprise and alarm that many of the “white-haired old ladies” took to swearing a lot of the time. She found the expressions of “fits this, fas that” hard to fathom and assumed the “f”word was more common than in England. She was palbably relieved when I explained they meant “what’s this”and “where’s that”, thereby easing her mind that she had not married into a culture of coarse swearers! + +## JIM WOOD + +OTTERY ST MARY, DEVON + +###### Good clean fun on the beach + +It’s not just the Australians who can celebrate without leaving masses of litter. On holiday in the South of France last summer, we were among thousands who filled the beach and streets at Valras-Plage to watch a spectacular firework display celebrating le 14 Juillet. When everyone left, the beach was spotless! + +## LYNNE PEMBERTON + +ABBOTS MORTON, WORCESTERSHIRE + +###### Slow driving is not dangerous + +It is a scandal that it is an offence to drive below the minimum speed limit (i, 2 January). In my opinion, no accidents are caused by slow drivers on motorways. + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +The accident is caused by others’ impatience, inattention, or loss of control. + +## M FOSTER + +SHROPSHIRE + +###### Setters getting sneakier + +I have been a moderately successful tackler of cryptic crosswords for many years, but I am finding them increasingly challenging. Occasionally, even after seeing the solution, I still don’t get it. Is this a sign that my 87-year-old brain is not quite up to the job or are the setters simply becoming more and more sneaky? + +## GEOFF IVORY + +FRINTON-ON-SEA, ESSEX + +###### No-show GP charges unfair + +Concerned about people missing doctors’ + +What have cupcakes got to do with cups, asks one reader AFP/GETTY + +appointments, Stuart Ackland suggests (Your View, 3 January) that patients have to make an advance credit\debit card “booking”, with a charge deducted for a no-show. + +But what about people like me who don’t have any such cards? With my GP practice, it is hard to get through on the telephone to make an appointment, and I regularly hang up after being kept on hold for ages. Might people similarly be calling to make a cancellation but are unable to get a response? + +## TIM MICKLEBURGH + +GRIMSBY, + +NORTH LINCOLNSHIRE + +###### Unfair certainly but not racist + +I completely agree with Deborah Orr (My View, 3 January) that the imposition of repatriation costs on women escaping from forced marriages abroad is unworthy of our government. However, I feel that her charge of racism on the part of the Foreign Office is unfounded. I am sure that any white British woman repatriated in similar circumstances would be presented with the same bill. + +## ROBERT BAYNHAM EXMOUTH, DEVON + +###### Stoking the fires of debate + +I was interested to read Alan MacDonald’s good humoured take on Stoke-on Trent’s location (Your View, 3 January). However confusion still reigns. He refers to Stoke-on-Trent as being undoubtedly the capital of the Potteries. Stokeon-Trent is the Potteries + +- a city of six towns of which Stoke is only one. I guess one could argue that the town of Stoke is the capital – but most people who live there give primacy to Hanley. + +## PHIL MANN + +HARROW, MIDDLESEX + +###### We need more than seatbelts + +According to government apologists, such as Amber Rudd, preparing for a “no deal Brexit”is a sensible precaution, just like wearing a seatbelt. This is transparently fallacious. Car travel is a necessary everyday activity, but threatening a “no deal Brexit”is a reckless game of chicken. Parliament should already have declared itself ready to reject any such option. TERRY JOHNSON WIRRAL + +## MORECOMMENToninews.co.uk + +## Our commitment + +We take very seriously our responsibility to maintain high editorial standards, and are grateful to readers for pointing out any errors. i adheres to the Independent Press Standards Organisation (Ipso) code of practice. If you wish to complain about our editorial coverage, especially with relation to inaccuracy or intrusion, please write to The Editor,i, 2 Derry Street, London, W8 5TT, or email i@inews.co.uk. You can contact Ipso directly at Gate House, 1 Farringdon Street, London, EC4M 7LG, telephone 0300 123 2220, or by email on inquiries@ipso.co.uk. + +# Plus + +###### LIFE + +## Running away from cancer + +After a shock diagnosis, Tim Buynon hit the road to find mental and physical solace + +###### TRAVEL + +# Rory Boland of Which? on why he hates Ryanair diff --git a/outputs/long_tiny_text/20_pg32_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg32_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..89946d265967e06e66f7de9ccb9bf16f93937b74 --- /dev/null +++ b/outputs/long_tiny_text/20_pg32_pg1_pg1_repeat1.md @@ -0,0 +1,47 @@ +##### FILM + +## ‘#MeToo stemmed from people not talking’ + +###### Continued from page 31 + +lious, bisexual French author, played by Keira Knightley, cut a scandalous dash through early 20th-century Paris. Gough plays Missy, Colette’s male-presenting lover. It is a distinct shift for her, not only because of the medium, but because of the character’s emotional reserve. Set against Knightley’s zealous trailblazer, Missy was “the quiet force of empowerment behind her”, Gough says. She warns against trying to understand Missy’s gender and sexuality using modern terms. “There were no words for lesbian or trans. Missy identified with both the female and male pronoun, so it’s hard to define whether she was one of the leaders of the butch lesbian movement or the trans movement.” Inevitably in the light of recent casting controversies, questions have arisen around a cis woman playing the part.Gough’s response is considered but firm. “I’m not going to apologise for my work, because that’s disempowering to me as a female who has worked as hard and for as long as I have.” But, she says, she welcomes the conversation. “If there is to be any outcry or any reason for the trans community to use this as another opportunity to become more visible, I am all for it.” Gough points out, Colette is progressively “blind” in its casting – with trans actors in cis roles and people of colour playing historically white characters – and she believes that such across-the-board fluidity should be the end goal. “I don’t want it to become so difficult that none of us can play anything but what we are, because I signed up to become an actor because I love all of it, I want to play all of it.” Gough’s career has been hard-won. Aged 15, she ran away from County Clare to London with a boyfriend, spending six years living in rat-infested squats. (“I am awareofhow fortunate Iam.Other girls died in those situations.”) After getting a full scholarship to drama school, she spent 15 years building a respected theatre career, while never knowing how to pay her rent. She was applying for cleaner jobs when People, Places, & Things came along. Now, at 38, she is being introduced to the more unreal echelons of the industry. With her rise have come rails of designer frocks, red carpets, flying film-festival visits, and the chance to meet her childhood idol Bruce Springsteen at a dinner at Anna Wintour’s house. But she’s not about to paint it as a fairy tale. “On the Tony trail, you have to do these lunches, I was like: ‘Why I am at a lunch for Denzel Washington? I don’t know him’ – the people serving me food were old enough to be my father. I thought ‘I can’t live in a country where people don’t have access to [the basics].’” Though her two New York stage turns were equally acclaimed, they weren’t equally enjoyable. People, Places & Things was the pinnacle of her career: “I was surrounded by people who loved me and whom I loved. Nobody was afraid of what I was doing.” Yet Angels in America was “a lonely thing, horrible. I think people would worry about me saying I hated it, but I don’t care.” Her candour is not careless, more a moral imperative: “All of this shit with #MeToo stemmed from people not talking.” When it comes to the past year’s reckoning with abuse, Gough says she has never really been “sexualised in the industry – I was too angry, I think – but I was bullied and undermined. It was horrible, but I always stood up to it.” Growing up, Gough “didn’t have any interest in screen, because I thought: ‘There doesn’t seem to be anything that deep going on’.” One TV audition sticks in her memory, however: she was testing out to play “a really political woman, and when I went to it , the director said: ‘The key to this character is in how she f**ks.’And I thought, that’s the end of that.” It is thrilling to think that Gough now has the leverage to find the film opportunities to match her stage appearances. Soon, she will star opposite Sebastian Stan in Monday, a “romcom gone wrong”. There are also rumours she is to take a key role in the forthcoming prequel to Game of Thrones. For the first time, Gough is lost for words. “Has that come out? That would be funny, wouldn’t it?” She smiles. Dissembling, it is clear again, is not her forte. + +![](figure) + +![](figure) + +###### ‘Colette’ (15) is out on Wednesday + +![](figure) + +![](figure) + +Strong suit Denise Gough as Missy in ‘Colette’ + +#### Filmof theweek + +## Knightley keeps this Paris literary drama lively + +# ALSOSHOWING + +## RBG (PG) + +HHHHH + +Dir: Julie Cohen, Betsy West, 98 mins, featuring: Ruth Bader Ginsburg Supreme Court Associate Justice Ruth Bader Ginsburg is such a well-known figure in American popular culture that she is known by her initials alone. “Law is a consuming love for me,” Ginsburg says, and the directors show how hard she had to fight to establish herself in such a male-dominated profession. While at Harvard Law School, she looked after her baby, tended her husband through cancer and still scored top marks in all her law exams. She worked on as little as two hours of sleep a night. Early on in the film, we hear her characterised as “a witch”, an “evil-doer” and “an anti- American zombie”. These are the kind of misogynistic slurs commonplace in today’s bitterly divided America. Ginsburg, though, had an uncanny knack of winning the respect and affection of most of her opponents. She likens herself to a “kindergarten teacher”, patiently explaining to chauvinistic and naive judges that, yes, sex discrimination really does exist. She made her arguments in such a precise and compelling way that she invariably won cases the media expected her to lose. RBG isn’t a critical portrait of its subject but it is an enlightening and affectionate one, with archive material balanced by plenty of footage of young lawyers who see Ginsburg as their ultimate role model. Geoffrey Macnab + +COLETTE (15) + +HHHHH + +Dir: Wash Westmoreland, 112 mins, starring: Keira Knightley, Eleanor Tomlinson, Dominic West, Fiona Shaw, Aiysha Hart, Denise Gough + +## Reviews by Geoffrey Macnab + +Fin-de-siècle Paris is recreated in extraordinarily vivid fashion in Wash Westmoreland’s Colette. For all the brilliance of its production design, though, and in spite of two very lively central performances, the film can’t overcome the challenge faced by every literary biopic; namely, how to dramatise a life of which large parts are spent sitting at a desk, writing. + +## ONE CUT OF THE DEAD (15) + +## HHHHH + +Dir: Shinichiro Ueda, 97 mins, starring: Takayuki Hamatsu, Mao, Harumi Syuhama, Yuzuki Akiyama When a zombie apocalypse breaks out during production of an indie zombie movie, its director decides to keep the cameras rolling. Is it real, or an elaborate ruse by a mediocre film-maker trying to get better performances from his cast? That’s a question this ultralow-budget Japanese zombie horror comedy starts unpacking and playing around with in surprisingly inventive ways, transforming what could have been just another derivative self-referential genre mash-up into a genuinely funny tribute to low-budget film-making. Alistair Harkness diff --git a/outputs/long_tiny_text/20_pg33_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg33_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..27df0958d32c4c633f97dceae6c69926521847d7 --- /dev/null +++ b/outputs/long_tiny_text/20_pg33_pg1_pg1_repeat1.md @@ -0,0 +1,94 @@ +Admiring glance Willy (Dominic West) recognises the talent of Colette (Keira Knightley) + +![](figure) + +![](figure) + +Keira Knightley plays aspiring author Colette as a passionate and fiercely independent figure. She is looking to establish an artistic identity of her own at a time when patriarchal wisdom has it that “lady writers don’t sell”. First seen as a 19-year-old in 1892, she is a young woman without a dowry or any obvious prospects. Colette may seem demure but that doesn’t stop her from having sex in the barn with the much older Henry Gauthier-Villars (known as “Willy”), a city slicker who served in the army with her father. Willy (Dominic West), who eventually becomes her husband, lures her from home to live in a Paris “heaving with artists and poets”. He is a dandy, a preening bon viveur, in love with his own voice. He writes stories and music reviews and likes to flirt with his hostesses in the smartest salons. Willy is a “literary entrepreneur”. He has no qualms about putting his name on Colette’s semi-autobiographical stories and basking in what should be her glory. West plays him as a flamboyant and likeable figure with a flair for marketing. They’re an attractive couple with a shared sense of mischief. We are aware from the outset that Colette is cleverer and more talented than her husband, who blithely fritters away the money they earn on gambling, race horses and women. It is also clear that he is the one who (whatever his motives) kick-started her career. The film-makers use waltz music and montages as we gallop + +## Willy and Colette are an attractive couple with a shared sense of mischief + +through the 1890s and early 1900s. Midway through, the film turns briefly into a farce as both Colette and Willy become enraptured by Georgie Raoul-Duval (Eleanor Tomlinson), a bisexual “wayward debutante from Louisiana”. Colette is far too strong a character to fall prey to romantic despair or to allow her spendthrift and philandering husband to upset her. Yet her ability to cope means the film is often short on tension. Whatever the situation, she makes the best of it. None of her relationships, whether with Willy or, later, with the androgynous aristocrat, Mathilde “Missy” de Morny (Denise Gough), are especially turbulent. The film deals with a relatively small part of its subject’s story, long before she wrote Gigi. This is the author in her formative years, and as a portrait of an artist as a young woman, the film is intriguing, Knightley excelling in the title role. But, as drama, it feels a little under-charged. THE INDEPENDENT + +# Ripples but no waves in staged melodrama + +## LIFE ITSELF (15) + +HHHHH + +Dir: Dan Fogelman, 117 mins, starring: Oscar Isaac, Olivia Wilde, Annette Bening, Mandy Patinkin, Olivia Cooke, Laia Costa, Antonio Banderas + +Life is the “ultimate unreliable narrator”. That is one of the greeting card-style nuggets of wisdom shared in Dan Fogelman’s trite and manipulative saga. Fogelman is one of many filmmakers in recent years to explore the butterfly effect: a small action by one character has a seismic ripple effect on the lives of others. Oscar Isaac plays Will, a dreamy New Yorker who, as a young student, waits for the perfect moment to ask out Abby (Olivia Wilde). They are so madly in love that it is inevitable that fate (or Fogelman) will play a few tricks on them. Some of the dialogue is stilted and self-conscious. Abby can’t resist talking about her thesis at length. By exploring the role of unreliable narrators in literature, she thinks she has discovered the secret of life itself. Fogelman tells the story out of sequence. It is full of flashbacks and leaps into the future. Will is shown in sessions with a therapist (Annette Bening), failing to pull himself together. In one scene, the sweet-natured figure from earlier has turned into a raging, drunken, disturbed hobo. + +The New York scenes are followed by a large section set in rural Andalusia, where the locals endure equally complicated emotional lives. Just as Will courted Abby, proud and hard-working farm worker Javier (Sergio Peris-Men-cheta) sets out to win the hand of the shy and charming Isabel (Laia Costa). The couple’s idyllic life is disturbed by Javier’s boss, Vincent (Antonio Banderas). Vincent is a grizzled and menacing figure but one prey to self-pity, too. Like most of the others here, he has been bruised emotionally by horrific childhood experiences. We can’t tell whether he wants to help Javier or steal Isabel. At least Banderas brings some charisma to his role. In an otherwise bland affair, English actress Olivia Cooke shows some welcome rebellious attitude as a young woman scarred emotionally by events in her earliest infancy and ready to hit out at anyone who teases her. The film touches again and again on the misery in its protagonists’ lives but never steps too far into the darkness. For all the talk about unreliable narrators,we can almost always guess how events will unfold. Coincidences abound and you are always so aware that Fogelman is pulling the strings that it is impossible to lose yourself in his story. THE INDEPENDENT + +## Star-cross’d? + +Laia Costa and Sergio Peris-Mencheta as Javier and Isabel + +![](figure) + +![](figure) + +###### Film Matrix + +##### WHATCRITICSARESAYINGABOUTTHENEWRELEASES + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +# REEL =TALK= + +##### ALICE JONES + +![](figure) + +![](figure) + +![](figure) + +‘Peep Show’ writer darkens Sundance + +A film written by Sam Bain (above) has been added to the line-up for this month’s Sundance Film Festival. Corporate Animals is a horror comedy starring Demi Moore as the CEO of an edible cutlery company whose team-building trip takes a dark turn. + +![](figure) + +![](figure) + +Bale’s Cheney keeps his shirt on + +Christian Bale (above) gained 60lb to play Dick Cheney in the biopic Vice, but a trailer shot of him in boxer shorts did not make the final cut. “One problem with a movie that’s six decades long is that it’s six decades long,” said director Adam McKay. + +![](figure) + +![](figure) + +‘A Quiet Place’ sequel to expand world + +John Krasinski has revealed details about a sequel to his cult hit A Quiet Place. It will revisit the apocalyptic world from “another perspective”: “The world is the star of the movie. You can drop whoever you want into it and everyone feels connected to it.” + +![](figure) + +![](figure) + +#### Spice Girls’ cartoon heroes knocked back + +The Spice Girls return to the stage this summer but their return to cinemas – following the 1997 film Spice World – is looking doubtful. The group has signed off on an animated superhero movie based on their alter egos, but it has yet to be picked up by a broadcaster or distributor. + +| COLETTE (15) | LIFE ITSELF (15) | RBG (PG) | ONE CUT OF THE DEAD (15) | +| --- | --- | --- | --- | +| “Colette is a character-driven movie, but also one that is sending a message about social mores and their malleability.” The Wall Street Journal | “The all-too-tidy web by which Fogelman’s ensemble of characters interconnect plays as hackneyed and contrived.” South China Morning Post | “Informs, and even delights with its portrait of one of the more remarkable lawyers, judges, and feminist icons of our time.” Village Voice | “Opens with monster mayhem before turning into a funny satire of genre film-making and then a charming family comedy-drama.” Variety | +| “Westmoreland’s Paris is scrumptiously decadent – and seedy – as Colette navigates the city’s gossipy social scene.” New York Post | “Made for people who can’t be trusted to understand storytelling unless it’s ladled on and explained via montage and voiceover.” IndieWire | “A celebration of the octogenarian not just as a pop-culture folk hero and millennial meme but as a wife, a warrior and a true iconoclast.” Entertainment Weekly | “Endlessly head-spinning, turning a riotous genre treat into a love letter to both film-making and film-watching alike.” The Daily Telegraph | diff --git a/outputs/long_tiny_text/20_pg35_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg35_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9787a50ff94500a598cd2cdb575507338ca34c0a --- /dev/null +++ b/outputs/long_tiny_text/20_pg35_pg1_pg1_repeat1.md @@ -0,0 +1,31 @@ +It was the year the boy next door learnt to roar. Ed Sheer- an, that superstar in a flannel shirt, left The Rolling Stones and U2 coughing on fumes as his Divide tour soared to a record-shattering gross of £378m. George Ezra graduated from floppy-haired debutant to bona fide superstar, his “Shotgun” single becoming the most-streamed rock song on Spotify in the UK. And as 2018 ended, a new contender looked set to emerge in the Elton John-championed Newcastle troubadour Sam Fender. He was winner of both the Brits Critics’ Choice Award and the BBC Sound Of prize – reliable barometers of talent poised for stardom (previous Sound Of picks include Adele and Sam Smith). Yet he will face stern competition.Kindred strummers Dermot Kennedy and Lewis Capaldi are also tipped to break big, each bringing their own blend of soulful lyrics and sensitive falsettos. None of these artists are soundalikes – but they do have a great deal in common, not least the old-fashioned art of standing alone on stage with a guitar and crooning. Image-wise, all could have dropped from the same production line. With his tatty T-shirts and high-street jeans, Sheeran has pioneered the lad-from-up-the-road look. In the past 12 months, however, he was pushed hard by 25-year-old Ezra and his gap-year backpacker chic. Twenty-two-year-old Capaldi, who has just wrapped a sold-out tour, looks as if he has tumbled out of a student bar on two-for-one night. Duncan Haskell, editor of Songwriting magazine, says: “We want to believe in what musicians of all genres are writing about, and maybe that’s easier if they look a little less glamorous.” What this new batch of bloke emoters lacks is the traditional whiff of brimstone. These stars are down-to-earth, devoid of guitar music’s untrammelled rawness. They are strikingly desexualised. “Nice” is the new rock’n’roll. “The boy with the guitar has always been there, but Ed has probably blazed a trail,” says Amy Wadge, the Wales-based songwriter who co-authored some of Sheeran’s biggest hits, including the 2014 number one “Thinking Out Loud”. “Because of the internet, the easiest way to deliver a song is to sit in front of a webcam with just a guitar and a voice. It’s connecting with people. “Back in the day, pop stars were presented in a certain way. That has changed with reality TV. People want to see someone they feel they know.” Ezra has been honest that, had he started out in the 80s or 90s, he is unlikely to have had a shot at fame. He simply can’t pull off the detached cool that was once de rigueur. “It wouldn’t work for me,” he told me in April, as his second LP, Staying at Tamara’s, was beginning its conquest of the charts: “There was a point on the first record when it started to do well and I thought, ‘Maybe I’ll have to adopt a persona.’ In fact, I’ve never had to. + +The rise and rise of the scruffy superstar + +With a new wave of guitar-toting troubadours set to break big this year, Ed Power explores how the boy next door conquered pop + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +“I have the luxury to admit: ‘I don’t party... here’s my record.’ Twenty years ago, I would have been ironically cool for admitting that, or you wouldn’t have gone near me.” Commercially, the boys of strummer have gone where few singer-songwriters have ventured before. Sheeran’s Divide tour holds the record for the highest-grossing run of dates in a calendar year. The 2017 album moved 672,000 units in its first seven days in the UK – the third-highest total in chart history and extraordinary in this age of flat-lined record sales. That same week, he had 16 tracks in the singles top 20 and nine in the top 10. Ezra, meanwhile, clocked up the fastest-selling long player of 2018 with Staying at Tamara’s. + +Reality TV changed everything. People want to see someone they feel they know + +Even “lesser” boy troubadours have enjoyed a blockbuster rise. James Bay’s debut album, Chaos and the Calm, debuted at number one. And despite a zero-star review from NME – prompting his dad to ring up to complain – Tom Odell’s first record likewise topped the charts. Fender has already racked up 1.2 million streams with his Tom Petty-esque rocker “Poundshop Kardashians”, despite still being relatively unknown. Understandably, none of these new singer-songwriters are keen to be pitched as a “Son of Sheeran”. At the same time, they don’t want to be construed as taking potshots at him. That’s another way in which the present crop stand apart: they are unfailingly polite and don’t do feuds. “[The Sheeran comparison] is a funny one,” says Kennedy, the Dublin singer-songwriter shortlisted for this year’s BBC Sound Of. “I don’t know if I should ever receive it as a negative thing, as he’s massively successful.” One unavoidable fact is that all of these artists are male. Where is the female Ed Sheeran? Why no Georgina Ezra? What does it say about the record industry – and the music-streaming public – that we can take these sloppy-grinned troubadours to our hearts while finding no room for the female equivalent? Adele is, for instance, every bit as much a phenomenon + +![](figure) + +![](figure) + +as Sheeran, yet she fits into the pre-existing tradition of gale-force soul belters. She doesn’t get to rip up the manual and write her own rules. It would be unthinkable that she could go on stage looking as if she’d just tumbled out of bed, as Sheeran did on the Divide tour. Compare also the buzz around Fender with the lack of excitement over female-fronted Wolf Alice winning the Mercury Prize for the year’s best album. Wadge recalls her own years as a struggling singer-songwriter and how her gender subtly became an issue. She was asked to lie about her age – “I was 25 for a very long time” – and to keep the + +Clockwise from main: Dermot Kennedy (and above), Lewis Capaldi, Sam Fender fact that she was married secret. “I always felt that there was room for only a few females,” she says. “My contemporaries were people like KT Tunstall, who was definitely better than me. There was an element of, ‘Why would we need you? We already have a girl with a guitar.’ Contrast how Sheeran parlayed YouTube popularity into a global following with the fate of Dodie Clark. She, too, started out posting heartfelt songs online. Despite her considerable live following, she has been categorised not as a songwriter but as a social media star – a novelty act. “I’m a woman and a ‘YouTube star’ in quotations,” she told me earlier this year. “Being taken seriously is very difficult.” It’s not just gender: almost without exception, these young male songwriters are white and middle class. So, too, are their audiences. Michael Kiwanuka, one of the few non-white songwriters to break through, found the situation so confounding that in 2016 he even released a single titled “Black Man in a White World”. “The fact that no black people were coming to my gigs made me realise we’re more segregated than we think,” he said at the time. One thing is clear, however: bumblingly real earnestness has acquired a cachet. Or at least it has if you’re a personable chap in his twenties. “There is a level of expectation that if you are going to sing about something, it should be something that matters,” says Wadge. “We see everything up close and personal. There’s no mystique any more.” + +![](figure) + +![](figure) diff --git a/outputs/long_tiny_text/20_pg39_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg39_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4ef7d71dfb8a53d96c35791d3002255d9fa84051 --- /dev/null +++ b/outputs/long_tiny_text/20_pg39_pg1_pg1_repeat1.md @@ -0,0 +1,130 @@ +Billy, might wonder where the sweetness lay. Annual seaside holidays in Rothesay provides one of his Proustian memories in this concluding half of his memoir, along with knitted woolly swimming trunks and “the poetry of swearing”. + +## === + +## Big Fat Quiz Of Everything 9pm, Channel 4 + +Following Christmas Eve’s Big Fat Quiz Of The Year, celebrity question-setters Jon Snow and Charles Dance (among others) tickle the much wider general knowledge of Sandi Toksvig – her QI training coming in handy here – Joe Lycett, Katherine Ryan, David Baddiel, Frank Skinner and Big Narstie. Jimmy Carr asks questions that range from Polish film titles to Digger the Crab. + +![](figure) + +![](figure) + +# FILM CHOICE + +# LAURENCE PHELAN + +![](figure) + +![](figure) + +![](figure) + +## FILM OF THE DAY The Wolf Of Wall Street 9pm, More4 + +(Martin Scorsese, 2013) Scorsese’s 21st feature film is adapted from an unrepentant tell-all memoir by Jordan Belfort (played by Leonardo DiCaprio, left), a cocksure but legally shady and morally repugnant founder of an upstart brokerage firm, who, before he was eventually brought low by an FBI investigation in the late 90s, amassed more wealth than Croesus would have known what to do with. It is an exhilarating, exhausting three-hour audiovisual bacchanalia of obscene conspicuous consumption, prostitutes and strippers, yachts and helicopters, drugs, sex and more drugs. And it is late-period Scorsese’s flashiest, funniest work by some margin. + +## === + +## What We Did On Our Holiday 10.50pm BBC2 + +(Andy Hamilton, Guy Jenkin, 2014) A sweet domestic comedy from the makers of the sitcom Outnumbered, viewed from the children’s focus but involving the divorce of parents Rosamund Pike and David Tennant and death of granddad Billy Connolly. + +## === + +## Mad Max 9pm, TCM + +(George Miller, 1979) + +In the taut little exploitation flick that made him a star, Mel Gibson plays a cop patrolling the highways of a post-apocalyptic future in a supercharged Ford Falcon GT, and grimly chasing down a biker gang with revenge in mind. + +![](figure) + +# ON DEMAND + +## My Brilliant Friend Now TV/Sky Box Sets + +Elena Ferrante’s novel about growing up in 50s Naples brought vividly to life. + +## The Marvelous Mrs Maisel + +Amazon Prime Rachel Brosnahan returns in a triumphant second season of the witty dramedy. + +## The Innocent Man Netflix + +True-crime series looks at murders in 80s Oklahoma. + +| ● 6.00 Classic Coronation | 6.00 Hollyoaks (S). 7.00 | 8.55 Food Unwrapped (S). | 6.00 Futurama (R) (S). 6.30 | 6.00 Fish Town (R) (S). | Radio BBC Radio 1 6am Weekend Breakfast With Matt And Mollie 10.00 | Project 5.00 PM 5.57 Weather 6.00 Six O’Clock News 6.30 The News Quiz. Topical comedy panel game, hosted by Miles Jupp. 7.00 The Archers. Helen throws caution to the wind. | 12.30 Steptoe And Son 1.00 Strong Poison 1.30 Precious Metal 2.00 History Of The Rain 2.15 The Invention Of Childhood 2.30 The Professor 2.45 Doubling Back 3.00 Bel | +| --- | --- | --- | --- | --- | --- | --- | --- | +| Street (S). 6.25 Classic | Couples Come Dine With | 9.30 A Place In The Sun: | Futurama (R) (S). 7.00 | 7.00 The Guest Wing (R) | Radio 1’s Greatest Hits With | 7.15 Front Row. John Wilson | Ami 4.00 Guess What? 4.30 | +| Coronation Street (S). | Me (S). 8.00 Melissa & Joey | Winter Sun (S). 10.35 A | Futurama (R) (S). 7.30 | (S). 8.00 Storm City (R) | Maya Jama 11.00 Maya Jama | presents. 7.45 Curtain Down | Anything Legal 5.00 Trapped | +| 6.55 Heartbeat (S). 7.55 | (S). 9.00 The Goldbergs | Place In The Sun: Winter | Futurama (R) (S). 8.00 | (S). 9.00 The West Wing | 12.45pm Newsbeat 1.00 Dev | At Her Majesty’s – A Play In | 5.30 The Rivals 6.00 Ghost | +| The Royal (S). 9.00 Lewis | (S). 9.30 The Goldbergs | Sun (S). 11.35 Four In A | Modern Family (R) (S). | (R) (S). 10.00 The West | & Alice 4.00 The Official | Five Acts. By Michael Chaplin. | Stories Of Walter De La Mare | +| (S). 11.00 On The Buses | (S). 10.00 The Big Bang | Bed (S). 12.05 Four In A | 8.30 Modern Family (R) | Wing (R) (S). 11.00 House | Chart With Jordan North 5.45 | Last in the series. 8.00 A | 6.30 Off The Page 7.00 I’m | +| (S). 11.30 On The Buses | Theory (S). 10.30 The Big | Bed (S). 12.35 Four In A | (S). 9.00 The Simpsons (R) | (R) (S). 12.00 House (R) (S). | Newsbeat 6.00 Radio 1’s Dance | Brief History Of Cunning. | Sorry I’ll Read That Again, | +| (S). 12.05 Rising Damp (S). | Bang Theory (S). 11.00 | Bed (S). 1.10 Four In A Bed | (S). 9.30 The Simpsons (R) | 1.00 Without A Trace (R) | Anthems With Jordan North | Joe Queenan revisits the | Again! 7.30 Steptoe And Son | +| 12.35 The Royal (S). 1.40 | Brooklyn Nine-Nine (S). | (S). 1.40 Four In A Bed (S). | (S). 10.00 Snake Boss (R) | (S). 2.00 Blue Bloods (R) | 7.00 Radio 1’s Dance Party | history of human duplicity | 8.00 Strong Poison 8.30 | +| Heartbeat (S). 2.40 Classic | 11.30 Brooklyn Nine-Nine | 2.10 Come Dine With Me | (S). 10.30 Snake Boss (R) | (S). 3.00 The West Wing | With Annie Mac 9.00 Pete | in the follow-up to his 2008 | Precious Metal 9.00 Podcast | +| Coronation Street (S). | (S). 12.00 Young Sheldon | (S). 2.40 Come Dine With | (S). 11.00 Big Beasts: Last | Special (R) (S). 4.00 The | Tong 11.00 Danny Howard | documentary. 8.50 A Point | Radio Hour 10.00 Comedy | +| 3.15 Classic Coronation | (S). 12.30 Young Sheldon | Me (S). 3.15 Come Dine | Of The Giants (R) (S). 12.00 | West Wing (R) (S). 5.00 | 1am Radio 1’s Essential Mix | Of View. Tom Shakespeare | Club: The Rivals 10.30 What To | +| Street (S). 3.45 Midsomer | (S). 1.00 The Big Bang | With Me (S). 3.45 Come | NCIS: Los Angeles (R) (S). | House (R) (S). | 3.00 Radio 1’s Mindfulness Mix | discusses remembering | Do If You’re Not Like Everybody | +| Murders (S). 5.55 | Theory (S). 1.30 The Big | Dine With Me (S). 4.20 | 1.00 Hawaii Five-0 (R) (S). | | 4.00 Radio 1’s Wind Down 5.00 | online passwords. 9.00 The | Else 10.45 Josie Long: All Of | +| Heartbeat (S). | Bang Theory (S). 2.00 Melissa & Joey (S). 2.30 Melissa & Joey (S). 3.00 | Come Dine With Me (S). 4.55 A Place In The Sun: Winter Sun (S). 5.55 The | 2.00 Hawaii Five-0 (R) (S). 3.00 S.W.A.T (R) (S). 4.00 Modern Family (R) (S). 4.30 | | Radio 1’s Wind Down BBC 6am Nick Radio Bright 10.00 1Xtra Reece | Art Of Now: Architecture Of Incarceration. Why modern prisons are based on a | The Planet’s Wonders 11.00 Elis James’ Pantheon Of Heroes 11.30 A Look Back At The | +| | Brooklyn Nine-Nine (S). | Supervet (S). | Modern Family (R) (S). 5.00 | | | 250-year-old design. 9.30 As | Future 12mdn’t Ghost Stories | +| | 3.30 Brooklyn Nine-Nine (S). 4.00 The Goldbergs (S). 4.30 The Goldbergs (S). 5.00 Young Sheldon (S). 5.30 Young Sheldon (S). | | The Simpsons (R) (S). 5.30 The Simpsons (R) (S). | | Parkinson 12.45pm Newsbeat 1.00 Snoochie Shy 4.00 Sian Anderson 5.45 Newsbeat 6.00 Sian Anderson 7.00 DJ Charlesy 9.00 Kenny Allstar 11.00 Sir Spyro 1am Kan D Man And DJ Limelight 4.00 | Others See Us. The historical relationship between India and Britain. Last in the series. 10.00 The World Tonight. With James Coomarasamy. 10.45 Book At Bedtime: Adrian Mole: The Cappuccino Years. By Sue | Of Walter De La Mare 12.30 Off The Page 1.00 Strong Poison 1.30 Precious Metal 2.00 History Of The Rain 2.15 The Invention Of Childhood 2.30 The Professor 2.45 Doubling Back 3.00 Bel Ami 4.00 Guess | +| | 6.00 The Big Bang | 6.55 The Supervet | 6.00 Futurama (R) | 6.00 House The | Diplo And Friends | Townsend. 11.00 Great Lives. | What? 4.30 Anything Legal | +| | Theory (S). | A five-year-old | (S). | team treats a | | Matthew Parris talks to Nikesh | 5.00 Trapped 5.30 The Rivals | +| | 6.30 The Big Bang | Great Dane | 6.30 The Simpsons | mobster (R) (S). | BBC Radio 2 | Shukla about Muslim wrestler, | | +| | Theory Sheldon | is rushed to | Marge and | | 6.30am Radio 2 Breakfast Show | the Great Gama. 11.25 The | BBC 5 Live | +| | does some | Fitzpatrick | Homer suspect | | 9.30 Ken Bruce 12noon Jeremy Vine 2.00 Steve Wright In The | Persistence Of Analogue. The growing popularity of analogue | 6am 5 Live Breakfast 9.00 Your Call 10.00 Chiles On Friday | +| | work with the | Referrals (S). | Bart might be a | | | | | +| | | | | | Afternoon 4.15 Steve Wright | hobbies in a digital world. | 1pm The Friday Sports Panel | +| | military (S). | | sociopath (R) (S). | | In The Afternoon – Serious Jockin’ 5.00 Ore Oduba 7.00 | 11.55 The Listening Project. 12mdn’t News And Weather | 2.00 Kermode And Mayo’s Film Review 4.00 5 Live Drive | +| 7.00 Murder, She | 7.00 Hollyoaks The | 7.55 Grand Designs | 7.00 The Simpsons | 7.00 CSI: Crime | Tony Blackburn’s Golden Hour | 12.30 Book Of The Week: Brief | 7.00 5 Live Sport 10.00 Geoff | +| Wrote Jessica | first day of | The conversion | A story | Scene | 8.00 Friday Night Is Music | Answers To The Big Questions | Lloyd 1am Up All Night 5.00 5 | +| becomes | Buster’s trial | of a Grade | chronicling | Investigation | Night 10.00 Sounds Of The | 12.48 Shipping Forecast 1.00 | Live Sport | +| involved in | begins (S). | II-listed barn in | Bart’s life (R) (S). | Grissom meets | 80s 12mdn’t Anneka Rice: The Happening 2.00 Fearne Cotton | As BBC World Service 5.20 Shipping Forecast 5.30 News | BBC 6 Music | +| astronomy and | 7.30 Young Sheldon | Essex (S). | 7.30 The Simpsons | a perceptive | | | | +| | | | | | 4.00 Huey Morgan | Briefing 5.43 Prayer For The | 7am Huw Stephens 10.00 | +| murder (S). | (S). | | Homer is fired | dominatrix (R). | | Day 5.45 IPM | Nemone 1pm Chris Hawkins | +| | | | (R) (S). | | BBC Radio 3 | | 4.00 Steve Lamacq 7.00 Iggy | +| | | | | | 6.30am Breakfast. 9.00 | BBC Radio 4 LW | Pop 9.00 Tom Ravenscroft | +| 8.00 Endeavour | 8.00 The Big Bang | | 8.00 Modern Family | 8.00 Blue Bloods | Essential Classics. 12noon | 9.45am Daily Service 12.01pm | 12mdn’t Nemone’s Electric | +| Morse | Theory The | | Phil goes on a | Danny and Baez | Composer Of The Week: | Shipping Forecast 5.54 | Ladyland 2.00 6 Music Classic | +| investigates an assassination | guys make fun of Zack (S). | | solo camping trip (R) (S). | investigate the murder of a | Gershwin. 1.00 News 1.02 Radio 3 Lunchtime Concert. | Shipping Forecast | Concert 3.00 6 Music Live Hour 4.00 Wise Women 5.00 | +| attempt at a | 8.30 The Big Bang | | 8.30 Modern Family | celebrity chef | Works by Rachmaninov and | BBC 6am Strong Radio Poison 4 6.30 Extra | Chris Hawkins | +| sporting event | Theory (S). | | (R) (S). | (R) (S). | Shostakovich. 2.00 Afternoon | | Classic FM | +| | | | | | Concert. Verdi’s Requiem and | Precious Metal 7.00 Trapped | | +| (S). | | | | | music by Raminta Serksnyte, Veljo Tormis and Esa-Pekka | 7.30 The Rivals 8.00 I’m Sorry I’ll Read That Again, Again! 8.30 | 6am More Music Breakfast 9.00 John Suchet 1pm Jane | +| | 9.00 FILM: X-Men: | 9.00 FILM: The | 9.00 Delicious | 9.00 Game Of | Salonen. 4.30 Words And | Steptoe And Son 9.00 Guess | Jones 5.00 Classic FM Drive | +| | The Last | Wolf Of Wall | Sam and | Thrones | Music. Tara Fitzgerald and | What? 9.30 Anything Legal | 7.00 Smooth Classics At Seven | +| | Stand (Brett | Street (Martin | Gina discover | Tommen | Giles Terera read poems | 10.00 Bel Ami 11.00 Podcast | 8.00 The Full Works Concert. | +| | Ratner 2006) | Scorsese 2013) | Mason is up to | confronts the | about violins, including Yeats | Radio Hour 12noon I’m Sorry | Catherine Bott features more | +| | Superhero | Drama, starring | something. | High Sparrow | and Whitman. 5.45 New Generation Artists. Mozart and | I’ll Read That Again, Again! | often overlooked composers. 10.00 Smooth Classics 1am | +| | adventure | Leonardo | | (R) (S). | Franck from three outgoing | | Katie Breathwick 4.00 Bob | +| | sequel (S). | DiCaprio (S). | | | New Generation Artists. 7.00 BBC Proms 2018. The Boston | Pick ofthe | Jones | +| 10.00Endeavour | | | 10.00The Late Late | 10.00Game Of | Symphony Orchestra perform | day | Absolute Radio | +| Morse | | | Show With | Thrones Jorah | Mahler’s Symphony No 3. 9.00 | | 6am Bush And Richie 10.00 | +| investigates the | | | James Corden: | and Daario | BBC Proms 2018. Featuring | | Leona Graham 1pm Ben | +| disappearance | | | Best Of The | undertake a | some of Cuba and Jamaica’s | | Burrell 4.00 Pete Donaldson | +| of a teacher from a secretive | | | Week With Sophie Turner | difficult task (R) (S). | influential musicians. 11.00 Music Planet. 1am Through | | 7.00 Absolute 80s With Claire Sturgess 10.00 Sarah | +| | | | | | The Night. | | Champion 4am Jay Lawrence | +| school (S). | | | (R). | | | | | +| | | | | | BBC Radio 4 | Composer Of | Heart | +| | 11.05 The Big Bang | | 11.00 A League Of | 11.10 Game Of | 6am Today 9.00 As Others See | The Week: | 6am Jamie And Lucy 9.00 Toby | +| | Theory Penny’s | | Their Own | Thrones Tyrion | Us 9.45 Book Of The Week: | Gershwin | Anstis 1pm Matt Wilkinson | +| | ex-boyfriend | | With Andros | seeks a strange | Brief Answers To The Big | | 4.00 JK 7.00 Club Classics | +| | | | | | Questions 10.00 Woman’s | Noon, BBC Radio 3 | 10.00 Lilah Parsons 1am James | +| | offers her a new | | Townsend and | ally (R) (S). | | | | +| | job (S). | | Micky Flanagan | | Hour 11.00 Perfect Husband, Pitiable Artist 11.30 Relativity | Donald Macleod | Stewart | +| | 11.35 The Big Bang | | (R) (S). | | 12noon News 12.04 Adrian | (above) charts | TalkSPORT | +| | Theory (S). | | | | Mole: The Cappuccino Years 12.15 You And Yours 12.57 | George Gershwin’s final years, a period | 6am The Alan Brazil Sports Breakfast With Ally McCoist | +| 12.05 Vera (S). 1.55 The | 12.05 Naked Attraction (S). | 12.35 8 Out Of 10 Cats | 12.00 A League Of Their | 12.15 Animals 12.50 | Weather 1.00 The World At | | 10.00 Jim White, Perry Groves | +| Secret Life Of Cats (S). 2.45 | 1.05 Gogglebox (S). 2.10 | Does Countdown (S). | Own (R) (S). 1.00 The Force: | Banshee (R) (S). 1.55 | One 1.45 New Year Solutions | in which he finally | And Bob Mills 1pm Hawksbee | +| Michael Flatley: A Night To | Tattoo Fixers: Extreme (S). | 1.40 Ramsay’s Kitchen | North East (R) (S). 2.00 | Banshee (R) (S). 3.05 Dexter | 2.00 The Archers 2.15 Drama: | formulated his | And Jacobs 4.00 Adrian | +| Remember (S). 3.40 Road | 3.05 Rude Tube (S). 4.00 | Nightmares USA (S). | The Force: North East (R) | (R) (S). 4.05 The West Wing | Deceit, Desire And The Viking | | Durham And Darren Gough | +| To Avonlea (S). 4.35 Road | The Big Bang Theory (S). | 2.40 Ramsay’s Kitchen | (S). 3.00 A League Of Their | Special (R) (S). 5.00 The | | magnum opus – | | +| | | | | | Helmet 3.00 Gardeners’ | | 7.00 The Season Ticket With | +| To Avonlea (S). 5.30 ITV3 | 4.40 Brooklyn Nine-Nine | Nightmares USA (S). 3.40 | Own (R) (S). 4.00 Monkey | West Wing (R) (S). | Question Time 3.45 Short | the opera Porgy | Danny Kelly 10.00 The Two | +| Nightscreen | (S). 5.00 Melissa & Joey (S). | Close | Life (R) (S). 5.00 Futurama | | Works 4.00 Last Word 4.30 A | And Bess. | Mikes 1am Extra Time With | +| | 5.25 Melissa & Joey (S). | | (R) (S). | | Good Read 4.55 The Listening | | Tom Latchem | diff --git a/outputs/long_tiny_text/20_pg40_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg40_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fd293d4cb704194ace52dac6b62d33747d7ad1ba --- /dev/null +++ b/outputs/long_tiny_text/20_pg40_pg1_pg1_repeat1.md @@ -0,0 +1,111 @@ +###### AGENDA + +# What’sontoday... + +##### Visual Arts + +## TURNER IN JANUARY + +Scottish National Gallery, Edinburgh This collection of nearly 40 fragile paintings, bequeathed to the gallery by the collector Henry Vaughan a century ago, only goes on show when the dim winter light poses minimal threat to them. The pieces span the artist’s career, from early wash drawings to sketches of Europe from the 1830s and 1840s. (0131 624 6200) to 31 Jan + +## FERNAND LÉGER: NEW TIMES, NEW PLEASURES + +Tate, Liverpool More than 40 works by the French artist and film-maker Fernand Léger (1881–1955), whose paintings, murals, film and textiles were infused with the bustle and rhythm of the urban environment and drew on the new forms of communication that boomed during the first half of the 20th century such as typography, advertising and graphic design. The show includes his collaborations with architects Le Corbusier and Charlotte Perriand and his experimental 1924 film, Ballet Mécanique. (tate.org.uk) to 17 Mar + +## ANNIE SWYNNERTON: PAINTING LIGHT AND HOPE + +Manchester Art Gallery The first retrospective for nearly a century of the Manchester-born painter, a pioneering professional artist who challenged convention in art and life, featuring 36 paintings from across her career, including rarely seen pieces on loan from private collections. This free + +# WIN A SPA BREAK FOR TWO AT CHAMPNEYS TRING + +## We have partnered with Champneys Health Spa to give i readers the chance to win a fabulous spa break for two at Champneys Tring, Hertfordshire. + +exhibition brings together landscapes, allegorical works and later portraits, revealing her as a continually inventive artist who engaged with current art movements as well as forging an independent style shaped by her experience of light and colour in Italy. (0161 235 8888) to 6 Jan + +## ARTIST ROOMS: ROBERT MAPPLETHORPE + +Atkinson, Southport Images by the American photographer from the Artist Rooms collection, one of the best holdings of his work in the world. The pieces on display at this free show include self-portraits, studies of flowers and portraits of artists and celebrities of the New York cultural scene in the 80s, including Patti Smith, Andy Warhol and David Hockney, as well as pieces from the late 70s and early 80s when Mapplethorpe was documenting the New York SM scene. (01704 533 333) to 23 Mar + +## MAGIC REALISM: ART IN WEIMAR GERMANY 1919-33 + +Tate Modern, London SE1 A year-long free exhibition of German art from between the wars, drawing on the holdings of the George Economou Collection and offering the rare opportunity to see artworks not ordinarily on public display. Under the magic realism banner, used by the artist and critic Franz Roh in 1925 to describe a shift from the art of the Expressionist era towards cold veracity and unsettling imagery, this show includes work by Otto Dix, George Grosz, Albert Birkle and Jeanne Mammen and others. (020 7887 8888) to 14 Jul + +## RIBERA: ART OF VIOLENCE + +Dulwich Picture Gallery, London SE21 The first UK show of work by Jusepe de Ribera (1591-1652), one of the giants of the Spanish Baroque, who spent most of his career in Naples, where he influenced artists including Salvator Rosa and Luca Giordano. This exhibition brings together loans from seven countries to explore, for the first time, an aspect of Ribera’s art for which he was renowned: violent depictions of saints and figures being flayed and flogged. (020 8693 5254) to 27 Jan + +## RICHARD POUSETTE-DART: BEGINNINGS + +Kettle’s Yard, Cambridge The first solo exhibition in the UK of work by Richard Pousette-Dart, a key figure of Abstract Expressionism and an early influence on Jackson Pollock. He was one of the first of the New York School to work on a monumental scale, and while he is primarily remembered for his painting, this exhibition highlights his works in sculpture and on paper, as well as his photography. (kettlesyard.co.uk) to Sun + +## MARTIN PARR: RETURN TO MANCHESTER + +Manchester Art Gallery The photographer has revisited Manchester many times over the past 40 years, since his years as a student at the Polytechnic in the early 70s, to document the ongoing lives of Mancunians. This free exhibition brings together a selection of his Manchester photographs, ranging from black-and-white images of June Street, in Salford, in 1972 and Yates Wine Lodges in 1982-3, to colour photos of people shopping in 1986 and 2008. + +## (0161 235 8888) to 22 Apr + +## ARTES MUNDI 8 + +National Museum, Cardiff The UK’s most political art prize returns, with five shortlisted artists competing for the £40,000 prize. Among them are the Cannes Palme D’Or-winning film director Apichatpong Weerasethakul, Citizenfour cinematographer Trevor Paglen and Moroccan artist Bouchra Khalili. (0300 1112 333) to 24 Feb + +##### Comedy + +## ANDY ZALTZMAN + +Soho Theatre, London W1 In The Certifiable History, the political comedian, satirist and “Radio 4 irregular” attempts to get a handle on 2018, a year in which the world has “barked furiously at its own reflection and punched itself in the face”. (020 7478 0100) to Sat + +## SAM SIMMONS + +Soho Theatre, London W1 Gleefully surrealist, wonderfully moustached Aussie Sam Simmons invites us to Soho to “witness the miracle birth of the baby Greg” and plenty of other such boggle-eyed, Christmas-derived horseplay in Away in a Stranger. (020 7478 0100) to Sat + +## WINTER WONDERLAND COMEDY CLUB + +Hyde Park, London W2 Luisa Omielan’s ace latest show, Politics for Bitches, focuses her smart, socially aware comedy + +Slip on a famous Champneys white robe and experience pure spa bliss, coupled with personalised marine wellbeing treatments. The perfect break for both your body and your mind. + +###### This superb prize for two people also includes: + + - A tour of Champneys and a nutritious welcome drink • Full access to Champneys’ range of fitness classes, spa and relaxation experiences + +- Champneys’ Marine and Wellness Spa Experience per person (up to 2.5 hours) • One night’s accommodation in a standard room + + - Healthy buffet breakfast, three-course buffet lunch and evening meal • Complimentary robe hire and flip flops + +## For more information visit + +###### www.champneys.com + +● + +![](figure) + +CHAMPNEYS +HEALTH SPA + +Pick up your copy of i from Monday 7 January 2010[^inferred] + +![](figure) + +CHAMPNEYS +HEALTH SPA + +Pick up your copy of i from Monday 7 January 2010[^inferred] + +Pick up your copy of i from Monday 7 January 2019 + +for details of how to enter + +JOHAN PERSSON + +###### Pick ofthe day + +![](figure) + +![](figure) + +THEATRE SWEAT + +Donmar Warehouse, London WC2 Lynn Nottage, a master detailer of the lives of the dispossessed, won her second Pulitzer Prize for this play, which, by turns profound, terrifying, earthy and witty, details the decline of a Pennsylvania town that was once a proud manufacturing hub. Lynette Linton’s superbly calibrated production shifts back and forth in time between 2000 and 2008, tracing the shifting dynamics of a close-knit trio of middle-aged female friends and their two twentysomething sons. (020 3282 3808) to 26 Jan + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/long_tiny_text/20_pg42_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg42_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..719a612c19f274c9637e797b75cc49646aa5686e --- /dev/null +++ b/outputs/long_tiny_text/20_pg42_pg1_pg1_repeat1.md @@ -0,0 +1,67 @@ +##### BOOKS + +# An Odyssey into 21st century Nigeria + +## AN ORCHESTRA OF MINORITIES + +Chigozie Obioma (Little, Brown, £14.99) + +## Review by Lucy Scholes + +Nigerian author Chigozie Obioma’s audacious debut, The Fishermen, captured everyone’s attention when it made the Man Booker shortlist back in 2015. In it, Obioma elevated the ordinary sibling rivalry between four brothers living in a small town in western Nigeria to the dizzying heights of Greek tragedy. A similar act of transformation can be found in his impressive, epic second novel, the narrative of which follows the (mis)adventures of one Chinonso Solomon Olisa, a humble 26-year-old poultry farmer in the Nigerian city of Umuahia. One day, while driving home from the market where he has purchased some new birds for his flock, Chinoso comes across a woman about to throw herself to her death from a highway bridge. In agitation, he grabs two of the fowl and tosses them over the bridge to demonstrate the gruesomeness of the death that awaits her. The young woman, a trainee pharmacist whose name is Ndali, is so struck by this intervention that she changes her mind. Chinonso drives home, “uncertain about what he had done, only knowing that he had done something out of the ordinary”. Ndali and Chinonso soon fall in love. They want to get married, but her family – who are much wealthier than Chinonso, and are perturbed by his lack of formal education – do everything in their power to foil the lovers’ plans. Thus, when an old school friend of Chinoso’s reappears in his life, claiming he’ll help his pal to enrol in a university on Cyprus – he can prove himself worthy of Ndali by earning his degree – Chinonso, “a man of instinct and passion”, rashly decides to sell all his possessions, including his house and farm, to fund the plan. In The Fishermen, Obioma knitted together Aristotelian tragedy with the oral storytelling traditions of his characters’ cultural heritage, and he takes a similar patchwork approach here. The narrative of An Orchestra of Minorities owes much to Homer’s Odyssey.Chinonso’s experiences in Cyprus are just as challenging as the struggles faced by his classical predecessor during his years of wandering. But Obioma blends these elements of the narrative with Igbo folklore and myth. The + +![](figure) + +![](figure) + +UpdatingaclassicObioma blends theHomerianwith IgbomythJASON KEITH + +# ALSORELEASED + +![](figure) + +THE ORDER OF THE DAY Éric Vuillard (Picador, £12.99) + +So often, history is about the consequences of mistakes by the weak and fallible. If the performance of our Brexit negotiators appears dubious, that is small beer compared with the craven dealings during the key meetings – all still within living memory – which could have prevented the Second World War. In this slim, disturbing volume the French writer and film director Éric Vuillard recreates some of them with striking imaginative flair. As he underlines repeatedly, the Nazis were bluffing almost all the way up to the outbreak of hostilities. Tragically, their adversaries rarely challenged them, let alone pushed back. First, Vuillard scrutinises the German business community. On a cold February day in 1933, two dozen industrialists and bankers gathered in the palace of the President of the Reichstag next to the River Spree. A smiling + +Hitler greeted these men of commerce and spoke about the necessity to resist communism. Then they all contributed huge amounts of money towards his imminent election campaign. The Nazis duly seized power. As Vuillard points out, many of these companies continue to prosper; some of them having profited from slave labour during the war. For the remainder of the book, Vuillard looks at the German annexation of Austria. He describes the visit of the British Foreign Secretary, Lord Halifax, to Germany in 1937. Halifax went hunting with Göring and afterwards, when he met Hitler, he intimated that the Führer’s designs on Austria and parts of Czechoslovakia did not seem unwarranted. This was like handing an arsonist petrol and matches. Later on, in 1940, Halifax decided he didn’t want to be Prime Minister, to lead the fight against the Axis forces – largely because he wanted to spend time with his mistress. Thankfully, Churchill got the job instead. Vuillard’s centrepiece is Hitler’s manipulation of the + +Austrian Chancellor Kurt von Schuschnigg in 1938. Vuillard takes us right inside the mind of Von Schuschnigg, a distinctly pusillanimous individual. They met at the Berghof, Hitler’s mansion high in the Bavarian Alps. Over the course of the day, Hitler threw a masterclass in intimidation. To place Von Schuschnigg off balance, the Führer alternated between threats and friendly overtures, while keeping him waiting on and off for hours. Eventually, von Schuschnigg caved in and signed an agreement which paved the way for the Nazi takeover of Austria. Vuillard explores the thoughts and feelings of his protagonists with nimble facility in this tour de force of enhanced realism. It is no surprise that it is a prize-winning best-seller in France – though whether the industrialists and politicians of the present ever learn much from their predecessors’ mistakes is moot. As Vuillard says: “We never fall twice into the same abyss. But we always fall in the same way, in a mixture of ridicule and dread.” Peter Carty + +1. Becoming Michelle Obama (Viking) + +2. The Story of Brexit: Ladybirds for Grown-Ups + +Jason Hazeley & Joel Morris (Michael Joseph) + +###### Top5 Books + +![](figure) + +3. Normal People Sally Rooney (Faber & Faber) + +4. The Ice Monster David Walliams (HarperCollins Children’s) + +5. The Tattooist of Auschwitz Heather Morris (Zaffre Publishing) + +![](figure) + +FRANCIS: A LIFE IN SONGS Ann Wroe (Jonathan Cape, £16.99) + +When Ann Wroe wanted to write a biography of St Francis of Assisi, she decided it was a life best expressed in poetry. And so comes about the structure of this extraordinary book. She starts each chapter with an extract from a biography of St Francis and perhaps a passage from Francis himself. Then she follows it with a poem about the episode, and follows that with a further poem about a loosely linked contemporary subject. The best parts of the book are, of course, the extracts from the life of Francis himself, which are remarkable in their lyrical simplicity. But the poems Wroe writes are haunting, too. Writing about the hut that Francis used for his followers, she says: “The tumbled struts were once/ a livestock place. Sour grassy-warm their breath in here, the trampled floor/ pungent and deep. The little group/ you’ve driven in, King Arthur’s knights,/ Bernard and Philip, Giles, the rest,/ Huddle as cattle do...” Next to this there are verses about a shepherd’s abandoned shack in Romney Marsh. A wonderful patchwork of prose and poetry. EVENING STANDARD Melanie McDonagh novel, for example, is narrated by Chinonso’s chi, the guardian spir- it who watches over man in Igbo cosmology. It’s a voice reminiscent of a Greek chorus: ever-watchful, knowledgeable, but unfortunately unable to intervene. Obioma’s interest in examining the tension between fate and self-determination also runs through both his novels. Poor, unfortunate Chinoso finds himself “wronged by man and history” – first he falls foul of a migration scam, and then finds himself falsely accused of attempted rape and murder (a not wholly convincing episode) – as a consequence of which, “a great darkness” enters him, “a crawly, multilegged darkness, shaped like a rapidly procreating millipede that burrowed into his life”. Where brother turning on brother in The Fishermen could be read as an allegory of post-in-dependence Nigeria, the parable here speaks to broader concerns about the cruelties of the contemporary world; about what the powerful do to the weak, and how a man can be expected to endure only so much before he begins to want to inflict the same torments on those who have hurt him. Timely, portentous and powerful, Obioma’s second novel confirms his remarkable talent. + +![](figure) + +SHE WAS THE QUIET ONE Michele Campbell (HarperCollins, £7.99) + +The murder of a twin points the finger at her sister, aka the quiet one. Centring on orphaned twins and their boarding school master and mistress, this is a tale of unrequited love and rule-breaking. The narrative flips between the main story and transcripts of police interviews with people involved in events in the run-up to the murder. Fans of Little Fires Everywhere by Celeste Ng will love the untangling of these seemingly perfect lives. Jenny Stallard + +![](figure) + +## SCRUBLANDS + +Chris Hammer (Wildfire, £16.99) + +![](figure) + +The Outback has become a go-to setting for crime thrillers. In a drought-scourged country town, a charismatic local priest guns down five men. A year on, a troubled journalist turns up to write a piece on the anniversary of the murders, and discovers that a seemingly open-and-shut case is anything but. Scrublands is well-plotted and atmospheric, but there’s almost too much going on as it explodes into life. Derek Watson diff --git a/outputs/long_tiny_text/20_pg46_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg46_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b71d3ea2081d4d379f9f2542d1e197c4aff98abc --- /dev/null +++ b/outputs/long_tiny_text/20_pg46_pg1_pg1_repeat1.md @@ -0,0 +1,61 @@ +Doyou wake up in the morning feeling rested and ready for the day ahead or do you rise with aches, pains and a fuzzy head from too little sleep? We spend up to a third of our lives in bed and, according to the Sleep Council – an independent organisation that raises awareness of sleep’s impact on health and wellbeing – a comfortable and supportive bed is the foundation of a restorative night’s slumber. Ensuring your mattress is doing its job is the first step to the best possible start to your day. + +## What types of mattress are there? + +Lots, and quality varies depending on the price. A budget mattress will usually be made up of open coil or sprung units. This continuous spring design consists of a single length of wire knitted into a series of interwoven springs; the higher the spring count, the more comfortable it will be. At the higher end sit pocket-sprung mattresses. These feature small metal springs, each sewn into their own “pocket” of fabric, making them individually responsive. More expensive designs will have up to 3,000 individual coils and include multiple layers of fillings including natural ingredients such as wool,cashmere,horsehair, silk or latex foam. + +## What is memory foam? + +![](figure) + +![](figure) + +Originally developed in association with Nasa, memory foam is made up of tightly knitted viscoelastic cells that respond to your temperature and weight, cushioning you and relieving pressure on joints. Called memory foam because of its ability to regain its original shape and structure rather than remember the shape of your body, it’s hypoallergenic, too. Initial problems with the foam retaining heat have mostly been dealt with by combining several foam layers, gel-infusing the foam, adding charcoal to aid breath-ability and even combining with pocket springs to create a hybrid mattress that some say offers the best of both worlds. + +## What size do I need? + +Available in standard UK single (90cm x 190cm), double (135cm x 190cm), king (150cm x 200cm), super-king (180cm x 200cm) and emperor (215cm x 200cm), there’s a mattress to fit every base. Some manufacturers have also cottoned on to the fact that we’re using bed bases in European sizes (from Ikea, for instance) and now produce non-standard continental sizes, too. If you already have a base, measure the flat, interior section to discover the size and buy accordingly. + +## How firm should it be? + +How heavy you are, the position in which you generally sleep and whether you’re a restless or light sleeper will all dictate the firm- + +More expensive designs will have up to 3,000 individual coils + +# And so to bed... + +A good mattress will ensure you wake up with a spring in your step. YsanneBrooks explores how to choose the right one + +ness of the mattress you choose. Most now come in variations of firm, medium-firm, medium-soft and soft, although some memory foam mattresses have just one comfort level. As a general rule, light and side sleepers should choose something that’s slightly softer while heavier back or front sleepers should go for the medium-firm or firm option. + +## Which type is best for back pain? + +What’s right for one person might not necessarily work for another, depending on size,age and weight. Your choice of mattress will also depend on the type of back condition you have so it might be worth a trip to your doctor for some advice first Back sleepers need support for their lower spine to prevent too much pressure on this area, so a medium-firm mattress that has enough hardness to support but a level of softness to cushion for added comfort is a good choice. Keeping the spine aligned is key if you’re a front sleeper, so a firmer mattress is better. Side sleeping + +#### How I found my fairy-tale mattress + +As I teenager, I slept on a sofa bed for three years and, as a student, a mattress on the floor. So to find myself, in my thirties, sleeping once again on a fold-out bed with Princessand-the-Pea-like layers of foam mattresses was too depressing for words. Enough was enough. + +I spent so much time researching “internet mattresses” (the groovy memory-foam beds that come in a box, like many of the ones in today’s ibuys, right) that my Instagram feed showed two mattresses to every one post from a friend. I agonised, I relaxes the spine and takes pressure off the back, making it the best position in which to sleep, and a softer or medium-firm mattress will allow the spine to rest in its most natural position. Memory foam or a memory foam-hybrid will help those with back pain as they contour and support your whole body. + +## What is a mattress topper? + +An additional layer of comfort for your mattress, removable toppers are available in a range of materials and depths, from latex, for a + +measured, I contemplated depth and potential sweatiness. I laid on display beds in retail parks and made decisions and then realised certain brands didn’t do the dinky size I needed. At an interiors event I went to for work, I squeaked with delight when I saw that almost every room, decorated by a different design company, had an internet mattress (Casper) in it. Ever the professional, by the end of the morning I had tried out each one When my Casper mattress arrived (£525 for a small double), it felt like Christmas. I unboxed it, unrolled it and set it on my bed base. Like the little bear’s porridge, it’s not too hot, nor too cold, but just right. My bed is now a cloud-like nest. My advice? Seek out a mattress that makes you feel like Sleeping Beauty. Rebecca Armstrong + +![](figure) + +![](figure) + +## Youneedtopick amattressthat’s right for you:Above:Kyoto Day-Bed,naturalbedcompany.co.uk + +firmer feel, to cotton and duck down for softness and warmth. Some memory foam mattress suppliers offer foam toppers to provide an additional layer. + +## What is a mattress protector? + +Many modern mattresses don’t require turning so it’s a good idea to top them with a removable protective layer that can be popped into the wash when necessary. Thinner than a topper, it’s not there to provide extra comfort, although some do, it’s more to help to preserve the life of a mattress and maintain freshness – particularly on children’s beds, for instance. + +## Mattress care + +The general consensus seems to be that a new mattress is advisable every eight to 10 years. There are ways to keep your mattress at its best for as long as possible, though.If your mattress t requires flipping and rotating then make sure you do this fairly regularly to ensure springs don’t get displaced or bunch in one position over time, or it doesn’t wear in one place. Flip the mattress once every three months and turn it top to tail at the same time. It’s important to keep your mattress clean, so try not to eat in bed. A regular vacuum will help to keep it dust- and mite-free. Adding a mattress protector is also a good preventative measure. diff --git a/outputs/long_tiny_text/20_pg48_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg48_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d0025d9f5eb38c750303403858cc1186e8a2b6f9 --- /dev/null +++ b/outputs/long_tiny_text/20_pg48_pg1_pg1_repeat1.md @@ -0,0 +1,77 @@ +# Quote of theday + +![](figure) + +![](figure) + +This is grim. The consensus always looked too optimistic, but this reading is at the bottom end of our expectations + +## Ian Shepherdson + +The Pantheon Macroeconomics economist on weak US manufacturing data + +## Business Editor Elizabeth Anderson + +![](figure) + +###### BANKING + +# Treasury appoints two women to Bank’s watchdog + +## By Holly Williams + +Two of the UK’s most prominent women in banking have been appointed to the Bank of England’s financial watchdog. Former Virgin Money boss Dame Jayne-Anne Gadhia has been named as an incoming external member of the Bank’s Financial Policy Committee (FPC), just days after being recognised in the Queen’s New Year’s Honours list. The Treasury also announced that Banking Standards Board chairwoman Dame Colette Bowe will join the FPC as it boosts the ranks of senior women on the committee. The Bank previously came under fire for missing its own targets on gender diversity. Last year it appointed two men to senior roles, including Sir Dave Ramsden on the + +![](figure) + +![](figure) + +# The 30 Second Briefing + +###### ABU DHABI ISLAMIC BANK + +![](figure) + +## Is this the UK’s most valuable bank branch? + +Bank branches are being shut by the hundred across the country, but at one of London’s most exclusive addresses – One Hyde Park – they’re still very much in demand. It is understood that a European investor has bought Abu Dhabi + +Monetary Policy Committee. The Treasury revealed that 20 of the 42 applicants for the FPC roles were women, with five women and three men reaching the shortlist stage. Chancellor Philip Hammond said: “The Financial Policy Committee’s importance to the protection and resilience of our economy cannot be overstated, which is why we have some of the finest talent in finance on it. “The insight and experience that both Dame Colette and Dame Jayne- + +![](figure) + +There was also a backlash to the Bank’s treatment of + +women last year when Deputy Governor Ben Broadbent described the UK economy as “menopausal” in May. + +Islamic Bank’s prestigious branch at the £1bn development for £27.5m — a £10m rise on when it was last sold six years ago. + +###### How did the deal come about? + +The undisclosed buyer paid the cash to a private Turkish vendor for the ADIB branch at 100 Knightsbridge, next door to Rolex’s store and McLaren’s supercar showroom. The new owner will get nearly £900,000 a year in rent from the investment and underlines the huge demand for commercial property in London despite Brexit uncertainties. One Hyde Park (pictured), created by the tycoon Candy brothers, is London’s most expensive private development. + +Anne bring will be valuable assets to the committee’s vital work.” Bank of England Governor Mark Carney added further praise for the new FPC hires. He said Dame Colette – also a former chairwoman of the regulator Ofcom – has “led the way in developing and embedding better standards of conduct across the banking sector”. He also welcomed Dame Jayne-Anne’s “deep and relevant experience in retail banking”. “In her public policy she has championed the transformative impact of adopting new technologies and of greater diversity within the workforce of the financial services industry,” he said. The duo will replace incumbent external FPC members Richard Sharp and Martin Taylor, who are stepping down at the end of the + +###### What is the bank? + +Abu Dhabi Islamic Bank, the second-largest Islamic lender in the United Arab Emirates, was founded in 1997. It opened its first UK branch in 2012 to target wealthy Gulf clients in Europe. Sheikh Khalid Bin Zayed Al Nahyan, a member of the Abu Dhabi royal family, joined Prince Andrew in opening the ADIB office. + +## Howdoes it differ fromatypicalhigh street bank? + +The principle behind Islamic finance is not to make money from money. Therefore, Sharia-compliant banks are not allowed to pay or charge interest. Instead, they make money by focusing on business, rental and trade activities to generate profits. + +![](figure) + +![](figure) + +Dame Jayne-Anne Gadhia joins the Bank’s Financial Policy Committee + +first quarter and second quarter respectively. Dame Jayne-Anne will take up her role in time for the FPC’s second quarter round of meetings, with Dame Colette taking up her post in time for the third quarter round. It comes after the ex-Virgin Money chief executive received a Damehood for her contribution to financial services and women in the finance industry; she was also appointed a CBE in 2014. + +###### ENERGY + +## DNO raises Faroe stake in takeover approach + +## By Ravender Sembhy + +The Norwegian energy firm DNO has warned takeover target Faroe Petroleum that it will not give up its pursuit of the North Sea oil producer. DNO, which is pushing for a £608m hostile takeover of Faroe, gained the backing of just 13 per cent of investors for the deal on Wednesday. But yesterday, it triggered a mandatory offer by taking its own stake in Faroe to the 30 per cent threshold. In doing so, chairman Bijan Mossavar-Rahmani said: “DNO is not going away. Even if DNO’s offer lapses or is allowed to lapse, DNO is not going away. For too long, shareholders have given the Faroe board of directors a free pass.” Faroe said DNO’s 152p-per-share offer was “opportunistic” and substantially undervalues the company. It described DNO’s attacks on Faroe’s exploration record and its implied criticism of the technical team as “puzzling”. Faroe shares rose 4.9 per cent to 153p yesterday. To succeed in its pursuit, DNO requires more than 57.5 per cent of investors to back the deal. Given it now owns more than 30 per cent of Faroe itself, the Norwegian firm has overall support from 43.1 per cent of the investor base. Earlier this week, Faroe hired industry experts at Gaffney, Cline & Associates to come up with their own valuation of the company, which concluded that its assets are valued in the range of 186p to 225p per share, or between \$879m (£688m) and \$1.1bn. diff --git a/outputs/long_tiny_text/20_pg49_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg49_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2ed92b9e4f36f63fa91e3d8068529762c0a5cf62 --- /dev/null +++ b/outputs/long_tiny_text/20_pg49_pg1_pg1_repeat1.md @@ -0,0 +1,99 @@ +![](figure) + +###### CONSTRUCTION + +# Brexit ‘headwind’ plunges sector to three-month low + +## By Ben Chu + +An “intense headwind” from Brexit played a part in plunging the UK’s construction activity to a three-month low in December,figures show. The Purchasing Managers’ Index in December came in at 52.8, down from 53.4 in November and the weakest since September. Subdued demand conditions were the main factor behind disappointing output growth in December, but there were also some reports that wet weather had held back work “Subdued domestic economic conditions and an intense headwind from political uncertainty resulted in the weakest upturn in commercial work for seven months,” said Tim Moore of IHS Markit,which compiles the PMI survey. “With a slight rise in new orders and a softening in overall activity growth, firms continued to be impacted by Brexit-related uncertainty and reluctance by clients to place orders, especially for commercial projects,” added Duncan Brock of the Chartered Institute of Procurement & Supply, a co-sponsor of the survey. Construction accounts for about 6 per cent of UK GDP. The most recent official data showed that the sector surged by 2.3 per cent in the third quarter of + +![](figure) + +![](figure) + +###### EMPLOYMENT + +2018, although this was partly catchup growth after heavy snowfall earlier in the year hit activity. “On past form, the average level of the PMI in Q4 is consistent with output remaining at Q3’s level,” said Samuel Tombs of Pantheon. Research from the Construction Industry Training Board released late last year suggested a third of UK construction firms are already feeling the effects of Brexit. Almost half the employers in the sector fear recruitment will become + +Construction accounts for about6per cent ofUKGDP GETTY + +harder over the next two years. It comes as data on the manufacturing sector this week showed firms are stockpiling goods and materials ahead of Brexit set for March. + +THE INDEPENDENT + +## Construction has been in + +![](figure) + +###### turmoil since the Brexit + +vote. Major current projects include Crossrail and plans to revamp Birmingham city centre. + +# Firms ‘should stop criminal record enquiries’ + +## By Alan Jones + +Firms are being urged to stop asking for criminal record details on job application forms because they give employers a “false sense of security”. Jobseekersarealso putoffapplying for work if they have to declare any + +# Outlook + +CARL MORTISHED + +![](figure) + +## The debate is heating up on carbon permits + +Everyone in the markets is feeling a little bruised after last year’s rout. UK investors are on average 12 per cent poorer, US stocks suffered their worst year since the crash. No one escaped punishment, except for one rather special group of investors. Anyone owning a hoard convictions upfront, according to a study for Virgin Trains and Business in the Community. The study called on companies to find more supportive ways to discuss potential recruits’ criminal backgrounds. Some candidates with no criminal record may actually pose + +of EUAs – that’s EU Allowances, for the uninitiated – is sitting on quite a windfall. These esoteric instruments – tradable permits to emit carbon dioxide – have soared by 200 per cent in a year, a gain that is causing hand-wringing, nail-biting and even panic in businesses that consume a lot of energy. It’s ringing alarm bells in governments from London to Warsaw and it will cause a huge political row in Westminster, if and when Britain leaves the EU. The EUAs are traded on the ETS, Europe’s cap-and-trade carbon Emissions Trading System, created in 2005 as part of the EU’s effort to encourage businesses to reduce their CO2 emissions. Businesses purchase a set number of allowances to emit CO2 every year; if they reduce their emissions, they can sell the allowances on the ETS. If they emit more, they must buy extra allowances, thus setting the price a greater risk of offending, it was claimed. Jessica Rose, of Business in the Community, said: “Asking everyone who applies for a role about criminal convictions at the start of the process tells people who are trying to move on with their lives that they won’t be given a fair chance.” + +for a tonne of CO2 and establishing a market cost for carbon reduction. It is the biggest such scheme in the world but in the early years,indulgent governments issued free permits and the EUA price fell to €5 per tonne, a level which made it profitable for power generators to burn coal rather than cleaner natural gas or + +## From being a bit of a joke, the Emissions Trading System is now working well – too well for some + +renewables. After a crackdown on allowance issuance, the carbon price has soared to almost €25 per ton. From being a bit of a joke, the ETS is now working well – too well for big electricity consumers, such as steel and chemical manufacturers who fret that power prices are soaring and allowances are expensive. British steel-makers are up in arms; industry lobbyist UK Steel + +## 4 JANUARY 2019 + +###### SERVICES + +## Costain’s order book hits £4.2bn as delays go on in Crossrail + +## By Holly Williams + +# £1.3bn + +![](figure) + +Extra funding needed to deliver Crossrail, on top + +Infrastructure services firm Costain notched a record order book for 2018 as it hailed “another year of progress”. Shares in the group – one of the contractors working on the delayed Crossrail project – rose 4.5 per cent to 339p as it said it finished the year with an order book at £4.2bn, up from £3.9bn at the end of 2017, and remains on track to meet full-year forecasts. It said this was helped by the trend for clients to consolidate supply chains to deliver increasingly lar ge , m ultibi lli on -pound investment programmes. The group – whose two largest customers are Network Rail and Highways England – said it had made further progress on its strategy to reposition itself to meet of the project’s original £15bn ingly complex cost and fast-chang-ing nature of its clients’ requirements”. Costain, which employs 4,000 people, finished 2018 with preferred bidder status on around £600m worth of contracts, up from £400m a year ago. Chief executive Andrew Wyllie said: “This has been another year of progress for Costain. “The benefits of our integrated offering, long-term strategic relationships with our clients and strong balance sheet position us well for the future.” It was announced last month that the Crossrail project could require an extra £1.3bn in funding, on top of the original £15bn cost, in order to be completed. The opening is likely to be delayed beyond its planned autumn 2019 launch. + +the “increasreckons its members pay power prices up to double those paid by French and German competitors. Last month, UK Steel published a series of demands, asking the Government to increase exemptions from the Renewable Levy, a subsidy to pay for greener energy. At the end of March, Britain is set to leave the EU. In the absence of a deal, we will fall out of the EU’s cap and trade carbon trading system. Hurrah, say libertarians, we can get rid of all these green taxes – electricity prices will plummet and UK steel will undercut France. But wait a minute. The Government says if that happens it will introduce a UK cap-and-trade system or a new carbon tax to make up the difference. No one wants to be seen to trash the planet. But when push comes to shove, which vote-grabbing measure would you prefer – a greener Britain or cheap electricity? EVENING STANDARD + +# From the business pages + +###### Big plans for new high-speed railway + +###### China Daily + +China plans to build 3,200km of new high-speed railways in 2019, with the total length expected to exceed 30,000km, the country’s top railway operator has said. China’s railways are expected to transport 3.54 billion passengers and 3.37 billion tons of goods this year, said China Railway. The country is also taking steps to introduce more digital tickets and flexible prices for the high speed trains. + +###### Manhattan home prices below \$1m + +###### Business Insider + +The typical Manhattan apartment has fallen below \$1m (£791,200) for the first time in three years. The median price of units sold in the borough from October to December fell nearly 6 per cent from last year to \$999,000, said property broker Douglas Elliman Real Estate. The fall is partly due to tax changes and prices are expected to remain weak. + +###### New tax for fizzy drinks and tobacco + +###### Gulf News + +The prices of tobacco products and sugary drinks in Qatar have gone up considerably after new taxes came in at the start of the year. A 50 per cent tax has been imposed on fizzy drinks and 100 per cent rate on tobacco products. A pack of Marlboro cigarettes that used to sell for QR11 (£2.41) now costs QR22. A 500ml bottle of Coca Cola has gone up from QR2 to QR3. + +###### Western Canada oil prices still strong + +###### The Calgary Herald + +Western Canada oil prices remain strong as Alberta production cutbacks kick in. The Alberta province announced last month that it would impose curtailments of 325,000 barrels per day as of 1 January to relieve a glut of oil in Western Canada and free up export pipeline space. The program, designed to remove about 8.7 per cent of Alberta production from the market, will be in place for three months. diff --git a/outputs/long_tiny_text/20_pg58_pg1_pg1_repeat1.md b/outputs/long_tiny_text/20_pg58_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3cc90665a42c7f2e55ec634ce9b65de1861cee16 --- /dev/null +++ b/outputs/long_tiny_text/20_pg58_pg1_pg1_repeat1.md @@ -0,0 +1,87 @@ +## 58 SPORT + +# Fantasy Football + +# Cardiff’s Bamba is worth a look in your defence + +The FA Cup third round means there are no points up for grabs this weekend but for fantasy managers looking to get their transfer business done early for game week 22, here are three picks worth considering. + +###### Danny Ings (Southampton) + +Since joining from Liverpool, Ings has featured in just 13 of Southampton’s Premier League fixtures this season and has completed the full 90 minutes on only four occasions. Despite this the English striker has managed seven goals – four more than any of his team-mates. With tricky fixtures against Manchester City and Chelsea out of the way, don’t be surprised if Ings adds to his tally in the coming weeks. Cost: £5.6m Points: 67 + +###### Sergio Aguero(Man City) + +Before he picked up an injury in game week 13, Aguero was a must-own player, scoring eight goals in 12 appearances. + +Since then he has been in and out of a City side that has stuttered in previously unthinkable fashion. Now, however, the Argentine appears to be back to full fitness. Cost: £11.2m Points: 92 + +###### Sol Bamba (Cardiff City) + +Cardiff were overwhelmed by Tottenham’s potent attack in game week 21, but the Bluebirds should fare better when they next take on the league’s two lowest-scoring teams in Huddersfield and Newcastle. Take advantage of these timid attacks by recruiting defender Bamba. The Ivorian has played all but one of Cardiff’s league fixtures this season and has chipped in with two goals and an assist in the process. Cost: £4.5m Points: 66 Finlay Greig + +###### i readers league + +1.Frippe Persson 2.Tony Russell 3.Tremaine Moore + +4. Robert Gomm + +###### 5.T Boogie + +6. Andrea Frostad + +7. Clive Hammerson + +8. Pete Clifton + +###### 9.Billy Grimshaw + +10. Stuart Ansell + +## Points + +1394 1385 1372 1355 1352 1346 1345 1338 1327 1323 + +![](figure) + +###### FA CUP TRANMERE ROVERS v TOTTENHAM HOTSPUR + +## Eriksen’s future may lie away from Tottenham, says Pochettino + +By Jonathan Veal + +Tottenham Hotspur manager Mauricio Pochettino accepts that Christian Eriksen has the right to ponder a future away from the club. The midfielder has been one of the star players for Spurs over the past few seasons as they have challenged at the top end of the Premier League but the Dane, who joined the club in August 2013, is reported to be stalling on a new deal. + +He is out of contract in the summer of 2020 but if he does not sign a new deal by the end of the current season, Spurs might be forced to listen to offers in order to get true value for the Denmark international. The 26-year-old (right) would not be out of place in any of the top sides in Europe and would be likely to earn a lucrative deal elsewhere. “I’m not a person that suffers too much in this type of situation because football is dynamic,” a relaxed + +Pochettino said before tonight’s FA Cup third round tie at Tranmere Rovers. “Football is about interests that as managers or head coaches we sometimes cannot manage. “It depends on many things in this business – different parties that have interests. “Of course Christian is such an important player for Tottenham and of course as a person or as a professional coach or manager, you would like to have this type of player with you. “But in the end it’s a negotiation and there’s different parties that have different interests. “It will be fantastic if Christian is going to be committed with the club for [the] long term, and if not it’s his right to do what he wants to do. “He is happy here, he is showing his commitment. Then what is going to happen in between him and the club is not only in our hands.” The futures of several other players at Spurs are likely to come under the microscope this month as a host of exits are expected. Outcasts Fernando Llorente, Vincent Janssen and Georges-Kevin Nkoudou are likely to leave the club, but established midfielder Mousa Dembélé could also be on his way out. The Belgian has only six months left on his current deal and with no new one on the horizon, Spurs could listen to offers in the transfer window to get some money for him, rather than lose him for free in the summer. “There is still no news,” Pochettino said. “No news, again like Christian – a different situation – it is not only in our hands. “In that business there are different parties that are involved, then it is about to negotiate, to talk, and see what the different parties want. “I don’t know [if he could leave on a free in the summer], that is going to be a club decision.” + +![](figure) + +![](figure) + +![](figure) + +# Freescoring Norwood spurred on to impress Kane + +## Tranmere striker would love to cause a cup shock tonight, he tells + +## Derren Howard + +JamesNorwood, the Tranmere Rovers striker, has scored more goals this season than Harry Kane. But as his side welcome Tottenham Hotspur in the third round of the FA Cup tonight, he is in no mood to give the England captain any extra motivation. Norwood has been in fine form this campaign for the League Two side and has two more league goals to his name than the England skipper. He is joint-top of the League Two scoring charts with 16 – despite failing to score for his last four matches – and the former England C international captain is keen to test himself against the eight-time FA Cup winners. “Tottenham have no real weaknesses and they give very little away,” said Norwood. “It is a huge task for us but one we and our fans are looking forward to. You see what they are doing to Premier League teams most weeks. With their power and skill levels, they are one of the most complete teams out there. Going forward, Harry Kane and [Heung-min] Son have just been incredible.” Rovers will take inspiration from Newport County’s fine FA Cup achievements last season. Last January, the team from south Wales forced a replay against Tottenham after a memorable 1-1 draw at Rodney Parade, before losing out 2-0 in the Wembley replay. “Newport showed the way. We will have to change what we do slightly and create an environment that will make it difficult for them,” he added. “Newport made it extremely tough for them and we have to look + +to do the same. The pitch here will not be what they are used to. We have to look for little gains and take advantage where we can.” Since joining Tranmere from Forest Green Rovers in 2016 the former Crystal Palace and Brighton youth striker has scored 68 times in 140 appearances – he has been the ultra-dependable goal-every-two-game type of forward. + +James Norwood still favours pink boots, having made his debut wearing them GETTY + +![](figure) + +![](figure) + +Norwood, 28, is out of contract this summer and his chairman Mark Palios, the former FA chief executive, has already said he doesn’t want to lose his main striker in the January window. An inspired performance against Spurs would increase his stock further but, the player who made his senior debut as a lightning quick 18-year-old with pink boots for Eastbourne Town + +![](figure) + +## There will be a full house at Prenton Park and hopefully we can deliver a performance to be proud of + +in the Ryman League South, says he just wants to concentrate on being part of something special for Tranmere. “It will be a proud moment,” admitted Norwood, who still favours his trademark pink boots. “I remember my time with Eastbourne Town and I learnt a great deal about adult football. To go from there and then to play Tottenham in the Cup is something special. “There will be a full house at Prenton Park and hopefully we can deliver a performance to be proud of. It would be a great time to get back on the scoresheet but we all know how tough it will be. “I started the season well but I missed a few good chances against Bury four games ago and I haven’t scored since. I had a bit of a sulk but we went through the clips and the manager said he is pleased with the other aspects of my play. It’s been very frustrating but all you can do is work hard for the team and get in the right positions. “I have had messages of support already and a few Tottenham fans have also been in touch wanting tickets and asking me not to injure any of their players!” Norwood has huge admiration for his opposite number Kane and the possibility of competing against him and a host of international stars is reward for a decade of toil in the lower leagues. “As a striker you have to admire what he has achieved. He seems to get better each season. He is always in the right place and when he gets his chance, he is lethal.” Ever since his days at Eastbourne, Norwood has also had the happy knack of doing just that. Should he get just one sniff of a chance against Spurs, he will need to be just as lethal as Kane. diff --git a/outputs/multi_column/0005784d0d255f6652180433936fa2998188_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0005784d0d255f6652180433936fa2998188_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d38976d9b16e09024206412b92455e887cc503dd --- /dev/null +++ b/outputs/multi_column/0005784d0d255f6652180433936fa2998188_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,18 @@ +# Incremental Coordination: Attention-Centric Speech Production in a Physically Situated Conversational Agent + +| Zhou Yu1 | Dan Bohus | Eric Horvitz | +| --- | --- | --- | +| Carnegie Mellon University | Microsoft Research | Microsoft Research | +| 5000 Forbes Avenue | One Microsoft Way | One Microsoft Way | +| Pittsburgh, PA | Redmond, WA | Redmond, WA | +| 15213 zhouyu@cs.cmu.edu | 98052 dbohus@microsoft.com | 98052 horvitz@microsoft.com | + +## Abstract + +Inspired by studies of human-human conversations, we present methods for incrementally coordinating speech production with listeners’ visual foci of attention. We introduce a model that considers the demands and availability of listeners’ attention at the onset and throughout the production of system utterances, and that incrementally coordinates speech synthesis with the listener’s gaze. We present an implementation and deployment of the model in a physically situated dialog system and discuss lessons learned. + +## 1 Introduction + +Participants in a conversation coordinate with one another on producing turns, and often co-produce language by using verbal and non-verbal signals, including gaze, gestures, prosody and grammatical structures. Among these signals, patterns of attention play an important role. Goodwin (1981) highlights a variety of coordination mechanisms that speakers use to achieve mutual orientation at the beginning and throughout turns, such as pausing, adding phrasal breaks, lengthening spoken units, and even changing the structure of the sentence on the fly to secure the listener’s attention. His work suggests that, beyond a simple errors-in-production view, “disfluencies” help to coordinate on turns, and generally facilitate co-production among speakers and listeners. Goodwin (1981) presents sample snippets of conversations recorded in the wild, annotated to show when the gaze of a listener turns to meet the gaze of the speaker (marked with *) and when mutual gaze is maintained (marked with an underline). In the examples reproduced below from Goodwin’s work, pauses and repeats are used to align grammatical sentences with a listener’s gaze: Anyway, Uh:, We went *t- I went ta bed Restarts can be used as a means of aligning the timing of a full grammatical utterance with the start of the process by which gaze is moving towards the speaker (process indicated by the broken underline), as in the following: She- she’s reaching the p- she’s at the *point I’m While most work to date in spoken dialog systems has focused on the acoustic channel in physically situated multimodal systems, an opportunity arises to use vision to take the participants’ attention into account when coordinating on the production of system utterances. We investigate this direction and introduce a model that incrementally coordinates language production and speech synthesis with the listeners’ foci of attention. The model centers on computing whether the listener’s attention matches a set of attentional demands for the utterance at hand. When attentional demands are not met, the model triggers a sequence of linguistic devices in an attempt to recover the listener’s attention and to coordinate the system’s speech with it. We introduce and demonstrate the promise of incremental coordination of language production with attention in situated systems. Following a brief review of related work, we describe the proposed approach in more detail in Section 3. In Section 4, we discuss lessons learned + +1 Research conducted during an internship at Microsoft Research diff --git a/outputs/multi_column/0005784d0d255f6652180433936fa2998188_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0005784d0d255f6652180433936fa2998188_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1641d319025458f843ba0276b7b75e555dbde029 --- /dev/null +++ b/outputs/multi_column/0005784d0d255f6652180433936fa2998188_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,9 @@ +information specified on the dialog act, but operates at the phrase level. In other words, the onset demand is checked at the beginning of every phrase in the dialog act. In addition to reasoning about onset attention, the proposed model also assesses if production demand is met at the end of phrases, i.e. if the accumulated attention throughout the phrase matched the production demand specified for the dialog act. If this is not the case, a wait is triggered (to re-acquire onset attention), and then the phrase is repeated. If the onset demand is met at any point during the wait, the system immediately repeats the phrase. The variability of the wait durations, coupled with variability in the attention estimates and the times when the specified onset or production attentional demand is met, leads to a variety of production behaviors in the robot. + +## 4 Deployment and lessons learned + +We implemented the model described above in the Directions Robot system and deployed it on three robots situated in front of the bank of elevators on floors 2, 3, and 4 of a four-story building. Appendix A contains an annotated demonstrative trace of the system’s behaviors. Additional videos and snippets of interactions are available at: http://1drv.ms/1GQ1ori. While a comprehensive evaluation of the model is pending further improvements, we discuss below several lessons learned from observing natural interactions with the robots running the current implementation. A first observation is that the usefulness and naturalness of the behaviors triggered by the robot hinges critically on the accuracy of the inferences about attention. When the model incorrectly concludes that the participants’ attention is not on the robot (false-negative errors), the coordinative policy triggers unnecessary pauses, interjections and phrase repeats that can be disruptive and unnatural. The attention inference challenge includes the need to recognize both the participants’ visual focus of attention (which in itself is a difficult task in the wild) and cognitive attention as being on task. Cognitive attention does not overlap with visual attention all the time. For example, at times participants would shift their visual attention away from the robot as they leaned in and cocked their ear to listen closely. Problems in inferring attention are compounded by lower-level vision and tracking problems. Second, we believe that there is a need for better integration of the coordinative policy with current existing models for language generation, gesture production, multiparty turn-taking and engagement. Beyond the number of words in a phrase, the current policy does not leverage information about the contents of phrases that are about to be generated. This sometimes leads to unnatural sequences, such as “Excuse me! By the way, would you mind [...]” Another important question is how to automatically coordinate the robot’s physical pointing gestures when repeating phrases or when phrases are interrupted. With respect to turn taking, problems detected in early experimentation led to an adjustment of the coordinative policy that we described earlier: the system does not move from a wait to a verbal action if it detects that the user is likely speaking. Beyond this simple rule, we believe that the floor dynamics in the turn-taking model need to take into account the system’s discontinuous production, e.g., take into account the fact that the pauses injected within utterances might be perceived by the participants as floor releases. Further tuning of the timings of the pauses, contingent on the dialog state and expectations about when the attention might return, as well as a tighter integration with the engagement model might be required. For instance, we observed cases where the robot’s decision to pause to wait for a participant’s attention to return from the direction that the robot was pointing (before continuing to the next phrase) was interpreted as the end of the utterance and the participant walked away before session completion. Third, we find that the definition of attentional demands (both onset and production) need to be further refined (in some cases on a per-dialog state basis) and modeled at a finer level of granularity, down to the phrase level. In an utterance like “By the way, would you mind swiping your badge?”, the “By the way” phrase is in fact an attention attractor, and itself does not require attentional demands and thus should be modeled separately. + +## 5 Conclusion + +We presented a model for incrementally coordinating language production with listeners’ foci of attention in a multimodal dialog systems. An initial implementation and in-the-wild deployment of the proposed model has highlighted a number of areas for improvement. While further investigation and refinements are needed, the interactions collected highlight the potential and promise of the proposed approach for creating more natural and more effective interactions in physically situated settings. diff --git a/outputs/multi_column/00187fe0533b1e8ddc748adab4924b6f7099_page_10_pg1_pg1_repeat1.md b/outputs/multi_column/00187fe0533b1e8ddc748adab4924b6f7099_page_10_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..26ff1bbaec632d4688e550c7efeb11c1212c69e6 --- /dev/null +++ b/outputs/multi_column/00187fe0533b1e8ddc748adab4924b6f7099_page_10_pg1_pg1_repeat1.md @@ -0,0 +1,79 @@ +comparison with reported CTS materials, CV curves, GITT calculations, CV calculations, and synthetic mechanisms (PDF) + +## AUTHOR INFORMATION + +## Corresponding Authors + +*E-mail: dlpeng@xmu.edu.cn. *E-mail: hangguo@xmu.edu.cn. *E-mail: mullins@che.utexas.edu. ORCID Jie Lin: 0000-0002-1281-9713 Duck Hyun Youn: 0000-0001-7338-6715 Yang Liu: 0000-0002-7240-1546 Kenta Kawashima: 0000-0001-7318-6115 Dong-Liang Peng: 0000-0003-4155-4766 Hang Guo: 0000-0001-9062-9678 Graeme Henkelman: 0000-0002-0336-7153 Adam Heller: 0000-0003-0181-1246 C. Buddie Mullins: 0000-0003-1030-4801 + +## Notes + +The authors declare no competing financial interest. + +## ACKNOWLEDGMENTS + +This work was supported by the Welch Foundation through Grants F-1131 (A.H.), F-1841 (G.H.), and F-1436 (C.B.M.), and the National Science Foundation through Grant No. CBET-1603491 (C.B.M.). J.L. thanks Hugo Celio, Karalee Jarvis, Richard Piner, and Dwight Romanovic for their characterization assistance. We also acknowledge the China Scholarship Council (CSC) scholarship under the State Scholarship Fund. + +# REFERENCES + +1. Grey, C. P.; Tarascon, J. M. Sustainability and In Situ Monitoring in Battery Development. Nat. Mater. 2017, 16, 45−56. + +2. Kwade, A.; Haselrieder, W.; Leithoff, R.; Modlinger, A.; Dietrich, F.; Droeder, K. Current Status and Challenges for Automotive Battery Production Technologies. Nat. Energy 2018, 3, 290−300. + +3. Winter, M.; Besenhard, J. O. Electrochemical Lithiation of Tin and Tin-Based Intermetallics and Composites. Electrochim. Acta 1999, 45, 31−50. + +4. Huang, B.; Pan, Z.; Su, X.; An, L. Tin-Based Materials as Versatile Anodes for Alkali (Earth)-Ion Batteries. J. Power Sources 2018, 395, 41−59. + +5. Wei, Z.; Wang, L.; Zhuo, M.; Ni, W.; Wang, H.; Ma, J. Layered Tin Sulfide and Selenide Anode Materials for Li- and Na-Ion Batteries. J. Mater. Chem. A 2018, 6, 12185−12214. + +6. Chao, D.; Ouyang, B.; Liang, P.; Huong, T. T. T.; Jia, G.; Huang, H.; Xia, X.; Rawat, R. S.; Fan, H. J. C-Plasma of Hierarchical Graphene Survives SnS Bundles for Ultrastable and High Volumetric Na-Ion Storage. Adv. Mater. 2018, 30, 1804833. + +7. Zhao, Y.; Wang, L. P.; Sougrati, M. T.; Feng, Z.; Leconte, Y.; Fisher, A.; Srinivasan, M.; Xu, Z. A Review on Design Strategies for Carbon Based Metal Oxides and Sulfides Nanocomposites for High Performance Li and Na Ion Battery Anodes. Adv. Energy Mater. 2017, 7, 1601424. + +8. Xu, J.; Ma, J.; Fan, Q.; Guo, S.; Dou, S. Recent Progress in the Design of Advanced Cathode Materials and Battery Models for High-Performance Lithium-X (X = O2, S, Se, Te, I2, Br2) Batteries. Adv. Mater. 2017, 29, 1606454. + +9. Arico, A. S.; Bruce, P.; Scrosati, B.; Tarascon, J. M.; van Schalkwijk, W. Nanostructured Materials for Advanced Energy Conversion and Storage Devices. Nat. Mater. 2005, 4, 366−377. + +10. Wu, F.; Yushin, G. Conversion Cathodes for Rechargeable Lithium and Lithium-Ion Batteries. Energy Environ. Sci. 2017, 10, 435−459. + +11. Cabana, J.; Monconduit, L.; Larcher, D.; Palacin, M. R. Beyond Intercalation-Based Li-Ion Batteries: The State of the Art and Challenges of Electrode Materials Reacting through Conversion Reactions. Adv. Mater. 2010, 22, E170−E192. + +12. Palacin, M. R. Recent Advances in Rechargeable Battery Materials: A Chemist’s Perspective. Chem. Soc. Rev. 2009, 38, 2565− 2575. + +13. Youn, D. H.; Stauffer, S. K.; Xiao, P.; Park, H.; Nam, Y.; Dolocan, A.; Henkelman, G.; Heller, A.; Mullins, C. B. Simple Synthesis of Nanocrystalline Tin Sulfide/N-Doped Reduced Graphene Oxide Composites as Lithium Ion Battery Anodes. ACS Nano 2016, 10, 10778−10788. + +14. Lin, J.; Lim, J. M.; Youn, D. H.; Kawashima, K.; Kim, J. H.; Liu, Y.; Guo, H.; Henkelman, G.; Heller, A.; Mullins, C. B. Self-Assembled Cu-Sn-S Nanotubes with High (De)Lithiation Performance. ACS Nano 2017, 11, 10347−10356. + +́ + +̈ + +15. Bombicz, P.; Mutikainen, I.; Krunks, M.; Leskela, T.; Madarasz, J.; Niinistö, L. Synthesis, Vibrational Spectra and X-Ray Structures of Copper(I) Thiourea Complexes. Inorg. Chim. Acta 2004, 357, 513− + +525. + +16. Jagminas, A.; Niaura, G.; Judzentiene, A.; Juskenas, R. Spectroscopic Evidence of a Novel Array Ac Fabrication within the Alumina Template Pores from Acidic Cu(II)-Thiourea Solution. Appl. Surf. Sci. 2004, 239, 72−78. + +17. Petit, C.; Bandosz, T. J. Mof-Graphite Oxide Composites: Combining the Uniqueness of Graphene Layers and Metal-Organic Frameworks. Adv. Mater. 2009, 21, 4753−4757. + +18. Jahan, M.; Liu, Z.; Loh, K. P. A Graphene Oxide and Copper-Centered Metal Organic Framework Composite as a Tri-Functional Catalyst for Her, Oer, and Orr. Adv. Funct. Mater. 2013, 23, 5363− 5372. + +19. Yang, D.; Velamakanni, A.; Bozoklu, G.; Park, S.; Stoller, M.; Piner, R. D.; Stankovich, S.; Jung, I.; Field, D. A.; Ventrice, C. A.; Ruoff, R. S. Chemical Analysis of Graphene Oxide Films after Heat and Chemical Treatments by X-Ray Photoelectron and Micro-Raman Spectroscopy. Carbon 2009, 47, 145−152. + +20. Ferrari, A. C.; Basko, D. M. Raman Spectroscopy as a Versatile Tool for Studying the Properties of Graphene. Nat. Nanotechnol. 2013, 8, 235−246. + +21. Stankovich, S.; Dikin, D. A.; Piner, R. D.; Kohlhaas, K. A.; Kleinhammes, A.; Jia, Y.; Wu, Y.; Nguyen, S. T.; Ruoff, R. S. Synthesis of Graphene-Based Nanosheets via Chemical Reduction of Exfoliated Graphite Oxide. Carbon 2007, 45, 1558−1565. + +22. Martin, L.; Martinez, H.; Poinot, D.; Pecquenard, B.; Le Cras, F. Comprehensive X-Ray Photoelectron Spectroscopy Study of the Conversion Reaction Mechanism of CuO in Lithiated Thin Film Electrodes. J. Phys. Chem. C 2013, 117, 4421−4430. + +23. Hu, X.; Jia, J.; Wang, G.; Chen, J.; Zhan, H.; Wen, Z. Reliable and General Route to Inverse Opal Structured Nanohybrids of Carbon-Confined Transition Metal Sulfides Quantum Dots for High-Performance Sodium Storage. Adv. Energy Mater. 2018, 8, 1801452. + +24. Lin, J.; Guo, J.; Liu, C.; Guo, H. Ultrahigh-Performance Cu2ZnSnS4 Thin Film and Its Application in Microscale Thin-Film Lithium-Ion Battery: Comparison with SnO2. ACS Appl. Mater. Interfaces 2016, 8, 34372−34378. + +25. Qu, B.; Ma, C.; Ji, G.; Xu, C.; Xu, J.; Meng, Y. S.; Wang, T.; Lee, J. Y. Layered SnS2-Reduced Graphene Oxide Composite − a High-Capacity, High-Rate, and Long-Cycle Life Sodium-Ion Battery Anode Material. Adv. Mater. 2014, 26, 3854−3859. + +26. Hu, R.; Ouyang, Y.; Liang, T.; Tang, X.; Yuan, B.; Liu, J.; Zhang, L.; Yang, L.; Zhu, M. Inhibiting Grain Coarsening and Inducing Oxygen Vacancies: The Roles of Mn in Achieving a Highly Reversible Conversion Reaction and a Long Life SnO2−Mn− Graphite Ternary Anode. Energy Environ. Sci. 2017, 10, 2017−2029. + +́ + +27. Laruelle, S.; Grugeon, S.; Poizot, P.; Dolle, M.; Dupont, L.; Tarascon, J. M. On the Origin of the Extra Electrochemical Capacity diff --git a/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9d47683ac2784605a1923471cb6bd732b037d36e --- /dev/null +++ b/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,57 @@ +![](figure) + +![](figure) + +# Instructions for Form 1116 + +#### Foreign Tax Credit (Individual, Estate, Trust, or Nonresident Alien Individual) + +Section references are to the Internal Revenue Code unless otherwise noted. + +### Paperwork Reduction Act Notice + +We ask for the information on this form to carry out the Internal Revenue laws of the United States. You are required to give us the information. We need it to ensure that you are complying with these laws and to allow us to figure and collect the right amount of tax. The time needed to complete and file this form will vary depending on individual circumstances. The estimated average time is: + +46 min. + +Recordkeeping ...................2 hr., 44 min. Learning about the law or the form ......................... Preparing the form ............1 hr., 53 min. Copying, assembling, and sending the form to the IRS ................................ + +55 min. + +If you have comments concerning the accuracy of these time estimates or suggestions for making this form simpler, we would be happy to hear from you. You can write to the IRS at the address listed in the instructions of the tax return with which this form is filed. + +## General Instructions + +## Purpose of Form + +Use Form 1116 to figure the foreign tax credit for certain taxes paid or accrued to a foreign country or U.S. possession. See Foreign Taxes for Which You May Take a Credit on page 2 to determine if the taxes you paid or accrued qualify for the credit. Do not use Form 1116 to figure a credit for taxes paid to the Virgin Islands. Instead, use Form 8689, Allocation of Individual Income Tax to the Virgin Islands. If you claim a foreign tax credit, you may be liable for the alternative minimum tax. Get Form 6251, Alternative Minimum Tax— Individuals, for details. + +For more information about how to figure the foreign tax credit, get Pub. 514, Foreign Tax Credit for Individuals. You can get it from an IRS Distribution Center. + +## Who Should File + +Use Form 1116 to figure your foreign tax credit if you are an individual, estate, or trust, and you paid or accrued foreign taxes for tax year 1995. If you are a nonresident alien, see Nonresident Aliens below. + +## How To Complete Form 1116 + +Use a separate Form 1116 (Parts I, II, and III) to figure the credit for foreign taxes paid or accrued for each category of income specified above Part I of the form. See Categories of Income on page 3 to find out what kind of income is contained in each category. If you have income from or have paid taxes to more than one foreign country or U.S. possession for one of the categories listed, use a separate column in Part I and a separate line in Part II for each country or possession, unless you meet the exception described below. If you paid taxes to more than three countries or possessions and do not meet the exception, attach additional sheets following the format of Parts I and II. + +## Exception to country-by-country reporting requirements.— + +Generally, if you received income from or paid taxes to more than one foreign country or U.S. possession, you must report information on a country-by-country basis on Form 1116, Parts I and II. However, this requirement does not not apply if: + +1. Your only foreign income was income in the passive income category on Form 1116, and the income (and any foreign taxes paid on it) was reported to you on Form 1099-DIV, Form 1099-INT, or a similar statement; and, + +2. The total of all your foreign taxes on Forms 1099-DIV (Box 3), Form 1099-INT (Box 5), and similar + +statements, does not exceed \$200 (\$400 if married filing jointly). If both of the above apply, complete Form 1116 as follows: Check the box for passive income above Part I. In Part I, do not use separate columns to report the income from each country. Instead, report all your foreign income in column A. On line j of column A, write “Various.” Complete the rest of the lines that apply to you in Part I. In Part II, complete only line A, columns (m) and (v). In column (m), write “12/31/95—Form 1099.” In column (v), enter the total foreign taxes from all Forms 1099-DIV, 1099-INT, or similar statements. Complete Parts III and IV of the form. + +## Credit or Deduction + +Instead of taking the credit on Form 1116, you may choose to deduct foreign income taxes on Schedule A (Form 1040). Generally, if you take the credit for any allowable foreign taxes, you may not take any part of that year's foreign tax as a deduction, either in the year you take the credit or in any later year. However, you may take a deduction for foreign taxes not allowed as a credit because of boycott provisions, even if you have taken the credit for other foreign taxes for the year. You may also deduct taxes paid to certain foreign countries for which a credit has been denied under section 901(j)(2), even if you take the credit for other foreign taxes. If you want to change your election to take a deduction instead of a credit or a credit instead of a deduction, you must do so within a special 10-year limitation period. See Pub. 514 for more details. + +## Nonresident Aliens + +If you are a nonresident alien, you generally cannot take the credit. However, you may be able to take the credit if: + +1. You are a resident of Puerto Rico during your entire tax year, or diff --git a/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..20927db0db3d16c13e231a02836eb7ffb820cb9a --- /dev/null +++ b/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,47 @@ +worksheet if it figured its tax using the maximum 28% tax rate on capital gains. For purposes of the worksheet, treat all numbers as positive amounts. Caution: If your capital gains or losses fall into two or more separate income categories (e.g., the passive category and the general limitation category), do not use the worksheet below. Instead, see Pub. 514 for information on how to report the amounts. + +## Worksheet for Capital Losses + +(Keep for your records.) + +1. Enter your net capital loss from foreign sources (to the extent taken into account in determining capital gain net income)...................................... + +2. Enter net capital gain* from sources within the United States. (This is the excess of net long-term capital gains from U.S. sources over net short-term capital losses from U.S. sources.) ........................... + +3. Enter the amount (net capital gain)* from line 2 of the Capital Gain Tax Worksheet you used to figure the tax for your return. (Estates and trusts should use line 37a of Schedule D (Form 1041).) ....................................... + +4. Subtract line 3 from line 2......... + +5. Multiply line 4 by .2929 ............. + +6. Subtract line 5 from line 1. This is your net capital loss from foreign sources. Enter this amount here and on line 5 of Form 1116................................. + +*Net capital gain does not include any amount that a taxpayer elects under section 163(d) to treat as investment income for purposes of the investment interest expense limitation. + +# High-Taxed Income + +In some cases, passive income may be placed in the general limitation income category. Passive income may qualify as general limitation income if the foreign taxes you paid on the income (after allocation of expenses) exceed the highest U.S. tax that can be imposed on the income. + +## Specific Instructions + +## Part I—Taxable Income or Loss From Sources Outside the United States + +## Line 1 + +Include any income in the category checked above Part I that is taxable by the United States and that is from sources within the country entered on line j. You must include this income even if it is not taxable by that country. Identify the type of income on the dotted line next to line 1. Do not include any earned income excluded on Form 2555, Foreign Earned Income. Use a separate Form 1116 for each category of income you are reporting. Example. If you received dividends (passive income) and wages (general limitation income) from a foreign source, you must complete two Forms 1116. On one Form 1116, enter the dividends on line 1 and write “Dividends” on the dotted line. On the other Form 1116, enter wages (not excluded on Form 2555) on line 1 and write “Wages” on the dotted line. Complete Parts I, II and III of each Form 1116. Then, complete the summary Part IV of one Form 1116. Note: If you are reporting income from a partnership or an S corporation, include on line 1 any amount from line 17c, Schedule K-1 (Form 1065) or from line 15c, Schedule K-1 (Form 1120S). + +## Allocating Deductions + +You must reduce your foreign gross income on line 1 by entering on lines 2 through 5: + +- A Any deductions you are taking that directly relate to that foreign income AND + +- A A ratable share of your other deductions that do not directly relate to either your foreign income on line 1 or your U.S. source income. + +Do not include deductions and losses related to exempt or excluded income such as foreign earned income excluded on Form 2555. Do not include the deduction for personal exemptions. Special rules apply to the allocation of research and experimental expenditures. See section 864(f). If the law of a U.S. state to which you pay income taxes does not specifically exempt foreign source income from tax, you may be required to make a special allocation of state taxes you paid. See Pub. 514. Itemized deduction limit.— If you are required to reduce the total amount of your itemized deductions on Schedule A (Form 1040), line 28, because your adjusted gross income was more than \$114,700 (\$57,350 if married filing separately), you must reduce each of the itemized deductions on Schedule A that are subject to the reduction by the reduction percentage before you complete lines 2, 3a, and 4 on Form 1116. Use the Itemized Deductions Worksheet in the Instructions for Schedule A (Form 1040) to figure the reduction percentage. Divide the amount on line 9 of the worksheet (the overall reduction) by the amount on line 3 of the worksheet (total itemized deductions subject to the reduction). This is your reduction percentage. Apply the reduction percentage to each itemized deduction to determine the amount to enter on the appropriate line of Form 1116. Example. You are single and have an adjusted gross income of \$164,700. Your itemized deductions subject to the overall reduction (line 3 of the worksheet) total \$20,000. This amount includes a deduction for gifts to charity of \$12,000. The other \$8,000 (\$20,000 – \$12,000) of itemized deductions are directly allocable to the income on Form 1116, line 1. The amount of the overall reduction on line 9 of the worksheet is \$1,500. To figure the amount of the charitable deduction to include in the total for line 3a of Form 1116, divide the amount on line 9 (\$1,500) by the amount on line 3 (\$20,000). This is your reduction percentage (7.5%). You must reduce your \$12,000 deduction by \$900 (7.5% × \$12,000). The reduced deduction, \$11,100 (\$12,000 – \$900) is the amount to include in the total for line 3a. Make a similar computation to figure the amount of directly allocable itemized deductions to enter on line 2 of Form 1116. Note: If you were required to reduce your itemized deductions on Schedule A, you do not need to make the computation described under Itemized deduction limit above if the total amount of your itemized deductions is entered on any one of the following lines: line 2, line 3a, or line 4a. Simply enter your reduced itemized deductions on that line. + +## Line 2 + +## Caution: Before you complete line 2, read Itemized deduction limit above. + +Enter all deductions that relate directly to the gross income from foreign sources shown on line 1. For example, if you are an employee reporting foreign earned income on Form 1116, line 2 may include expenses such as those incurred to diff --git a/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a6e29c825b732471c9618e5a622eb23c8f8692d8 --- /dev/null +++ b/outputs/multi_column/0083fb2109e58be50aec2eca07fcbfe1230b_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,45 @@ +and no reduction was made to U.S. source income. In situations where U.S. source income is reduced (the loss to be allocated exceeds foreign income in other categories), you must follow the rules described below under Recapture of prior year overall foreign loss. Note: If, for any tax year, you are required to allocate a foreign loss, you will need to make certain adjustments to income you receive in the loss category in later years. See Recharacterization of income below. + +2. Recapture of prior year overall + +foreign loss.— If you had an overall foreign loss in a prior year that offset U.S. source income, a part of your foreign income (in the same category as the loss) is treated as U.S. source income in each following tax year. + +The part that is treated as U.S. source income is the smallest of: (a) the amount of overall foreign loss not recaptured in earlier years, (b) 50% or more of your taxable income from foreign sources from all categories, or (c) the amount from line 14, less any adjustment for allocation of losses from other categories, described on page 7. Reduce the income on line 14 by entering (in parentheses) on line 15 the smallest of (a), (b), or (c) above. This is the amount of the recapture. Be sure to attach your computation. If you elect to recapture more of an overall foreign loss than is required, you must show in your computation the percentage of taxable income recaptured and the dollar amount of the recapture. Regulations section 1.904(f)-1(b) requires that you attach a statement to Form 1116 showing the balance in + +each separate limitation overall foreign loss account. + +3. Recharacterization of income.— + +If, in 1994, you reduced your foreign taxable income in the category shown at the top of Form 1116 by a pro rata share of a loss from another category, you must recharacterize in 1995 all or part of any income you receive in 1995 in that loss category. Increase the amount on line 14 by entering on line 15 any recharacterized income. + +Also include on line 15 any income required to be recharacterized in 1995 as income in the category shown at the top of Form 1116 because of a foreign loss allocation in prior tax years. Example. Using the same facts in the example under 1 on page 7, in the subsequent year (1996), you have \$5,000 of general limitation income, \$3,000 of passive income, and \$500 of high withholding tax interest. Because \$1,600 of the general limitation loss was used to reduce your passive income in 1995, \$1,600 of your 1996 general limitation income must be recharacterized as passive income. Similarly, \$400 of the general limitation income must be recharacterized as high withholding tax interest. On your 1996 Form 1116 for passive income, you would enter \$1,600 on line 15. On your 1996 Form 1116 for high withholding tax interest, you would enter \$400 on line + +15. Note: Recharacterization of income from a separate category does not result in recharacterizing any tax. + +4. Allocation of U.S. losses.— If you + +have a net loss from U.S. sources in 1995, you must proportionately allocate that loss among the separate categories of your foreign income. + +Reduce the income on line 14 by entering (in parentheses) on line 15 the allocable portion of any U.S. loss. A U.S. loss includes a rental loss on property located in the United States. + +## Line 17 + +If you figured your tax using the Capital Gain Tax Worksheet in the Instructions for Form 1040, use the worksheet below to figure the amount to enter on line 17. An estate or trust that used the maximum 28% tax rate on capital gains should also complete the worksheet. + +# Worksheet for Line 17 + +1. Enter the amount (net capital gain)* from line 2 of the Capital Gain Tax Worksheet used to figure the tax for your return. Estates and trusts: Enter the amount from line 37a of Schedule D (Form 1041) .......... + +2. Individuals: Enter the amount + +from Form 1040, line 35. Estates and trusts: Enter taxable income without the deduction for your exemption ... + +3. Multiply line 1 by .2929 ............. + +4. Subtract line 3 from line 2. Enter the result here and on Form 1116, line 17.................... + +*Net capital gain does not include any amount that a taxpayer elects under section 163(d) to treat as investment income for purposes of the investment interest expense limitation. + +## Part IV—Summary of Credits From Separate Parts III + +Complete this part on only one Form 1116 to summarize the credits you figured on separate Forms 1116. Enter the credits from line 21 of the separate Forms 1116 on lines 22 through 29, as appropriate. File the other Forms 1116 as attachments. diff --git a/outputs/multi_column/00922ce2b476b7fd200a009b191af89c84f6_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/00922ce2b476b7fd200a009b191af89c84f6_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6bd0648ddcdc65286bcdae683ec6ac663f1ae467 --- /dev/null +++ b/outputs/multi_column/00922ce2b476b7fd200a009b191af89c84f6_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,79 @@ +## Methods + +## Study design and participants + +We did this three parallel group, randomised controlled trial in Auckland, New Zealand. First randomisation was on Sept 6, 2011, and last follow-up was on July 5, 2013. The published protocol describes procedures in detail.[^13] In brief, people were eligible if they were aged 18 years or older, had smoked ten or more cigarettes per day for the past year, wanted to stop smoking, and could provide consent. We recruited via community newspapers, inviting people to call the study centre for eligibility prescreening, done by research assistants, who also completed follow-up assessments. We excluded pregnant and breastfeeding women; people using cessation drugs or in an existing cessation programme; those reporting heart attack, stroke, or severe angina in the previous + +657 randomised + +1293 assessed for eligibility + +2 weeks; and those with poorly controlled medical disorders, allergies, or other chemical dependence. Participants were mailed study information, and consent forms to sign and return. The Northern X Regional Ethics Committee approved the study (Number NTX/10/11/111); the Standing Committee on Therapeutic Trials approved the use of nicotine e-cigarettes because they were not permitted for sale in New Zealand, but could be imported for personal use or research. + +## Randomisation and masking + +Callers who met the inclusion criteria and gave demographic details and information about nicotine dependence (Fagerström test for nicotine dependence [FTND]14) were randomised by the study statistician (VP) in a 4:4:1 ratio to nicotine e-cigarettes, patches, or placebo + +636 excluded 202 did not meet inclusion criteria 162 declined to participate 272 other reasons + +289 assigned to nicotine e-cigarettes 289 received allocated intervention + +295 allocated to nicotine patches 295 received allocated intervention + +73 allocated to placebo e-cigarettes 73 received allocated intervention + +| 13 lost to follow-up | 27 lost to follow-up | 6 lost to follow-up | +| --- | --- | --- | +| 3 discontinued | 16 discontinued | 1 discontinued | + +273 assessed on quit date + +[^13]: lost to follow-up + +260 assessed at 1 month follow-up + +15 lost to follow-up + +245 assessed at 3 month follow-up + +2 lost to follow-up 1 discontinued 1 death + +241 assessed at 6 month follow-up + +289 included in analysis (ITT) + +## Figure 1: Trial profile + +252 assessed on quit date + +17 lost to follow-up 3 discontinued + +232 assessed at 1 month follow-up + +6 lost to follow-up 2 discontinued + +224 assessed at 3 month follow-up + +8 lost to follow-up 1 discontinued + +215 assessed at 6 month follow-up + +295 included in analysis (ITT) + +66 assessed on quit date + +4 lost to follow-up + +62 assessed at 1 month follow-up + +3 lost to follow-up + +59 assessed at 3 month follow-up + +2 lost to follow-up + +57 assessed at 6 month follow-up + +73 included in analysis (ITT) + +11 protocol violations occurred in the nicotine e-cigarettes group (three pregnancies, seven no biochemical validation, one undisclosed medication ineligibility). 11 protocol violations occurred in the patches group (four pregnancies, four no biochemical validation, three undisclosed medication ineligibility). Three protocol violations occurred in the placebo e-cigarettes group (one no biochemical validation, two undisclosed medication ineligibility). ITT=intention to treat. diff --git a/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8e62b3be2f0e6226feb718dac9b5535690b46d7c --- /dev/null +++ b/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,93 @@ +### 3.2 Mechanical parameters identification + +Figure 4 and Figure 5 show the plotted response curves as a least square estimation of the measurements for both blocked table and free table configurations. + +![](figure) + +![](figure) + +Fig. 4. Response curve of the isolation studs and the one DOF estimation in the blocked table configuration. With fn the natural frequency and \(\xi\) the damping ratio. + +![](figure) + +![](figure) + +Fig. 5. Response curve of the vibrating table and the one DOF estimation in the free table configuration. With fn the natural frequency and \(\xi\) the damping ratio. + +The responses of the system correspond to 1DOF oscillators and using a least square estimation we obtained the values of the mechanical parameters. Those values are given in Table 1 with respect to the parameters given by the manufacturer. + +### 3.3 Modal parameters + +The developed method requires an external possibility of making the shaker vibrate and is quite difficult to apply to larger shakers. In this case, modal analysis is an alternative since the mechanical parameters and the modal ones are equivalent to characterize the system. In this section, a short review of the modal theory will be presented to sufficiently master this equivalence as the relationship between movement, global coordinates, modal coordinates, and modal parameters. + +Table 1. Mechanical parameters + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
ParameterSymbolValues
Given by the manufacturer[6]Determined experimentally
Mass of the vibrating tablemT60 g76 ga
Mass of the bodyMB8.3 kg8.375 kg
Damping of the suspension of the coilcT–35.43 Ns/m
Damping of the isolation studscB–564.3 Ns/m
Stiffness of the suspension of the coilkT12·103 N/m11.95·103 N/m
Stiffness of the isolation studskB–3.06·105 N/m
+ +## aFor testing purposes, the original vibrating table is equipped with an extra 16 g fastening bolt. + +#### 3.3.1 Theoretical aspects + +If we only consider the purely mechanical system as depicted in Figure 2(a), the global equations (1) can be generalized by: + +\[MzCzKzF\] (2) + +Where M, C, and K are respectively the mass, damping, and stiffness matrices of the system. Solving the eigenvalues problem for the free undamped system yields the transformation matrix P between the modal coordinates q and the global coordinates z according [7]: + +\[zPq\] (3) + +The premultiplication by PT allows to diagonalize M and K since both are symmetrical. Despite that C is also symmetrical, the damping matrix cannot be diagonalized and we can consider a linear combination of M and K [8]. Considering this, we now can express (2) as: + +\[m_{i}q_{i}c_{i}q_{i}k_{i}q_{i}Q_{i}(i1,2)\] (4) + +The modal parameters mi, ci, and ki are respectively the modal mass, damping and stiffness of the ith mode. Qi is the modal force and qi is the modal coordinate of the ith mode. Whereas the system described by (2) is coupled, the system described by (4) is uncoupled since all the matrices have been diagonalized. The solutions qi to the decoupled equations are given by: + +\[q_{i} \frac{Q_{i}}{(k_{i}m_{i}^{2}jc_{i})} \frac{Q_{i}}{Pk_{i}} (i1,2)\] (5) + +Pki is the characteristic polynomial of mode i and j is the complex constant. diff --git a/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..578876b4e91830e03ff11b84520a38c8dad0b85f --- /dev/null +++ b/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,35 @@ +Using the matrix formulation, the real coordinate solution z can be obtained from (3) and expressed by: + +\[z \frac{P^{T}P}{Pk} FH_{ij}F\] (6) + +With F the global force vector representing the real forces applied in each DOF and Hij the dynamic influence coefficient matrix. + +#### 3.3.2 Modal parameters calculation + +Using both mechanical equations (1) and values from Table 1, we are able to compute the modal parameters and the dynamic influence coefficient matrix. These functions are represented in Figure 6 for the undamped system and in Figure 7 for the damped system. + +![](figure) + +![](figure) + +Fig. 6. Dynamic Influence Coefficient Matrix for the undamped system. The modal node 1 corresponds to the vibrating table whereas the modal node 2 corresponds to the body of the shaker. + +![](figure) + +![](figure) + +Fig. 7. Dynamic Influence Coefficient Matrix for the damped system. The modal node 1 corresponds to the vibrating table whereas the modal node 2 corresponds to the body of the shaker. + +Figure 6 is clearer for mode detection than Figure 7 and shows two modes occurring at 30.2 Hz and 63.5 Hz. This is consistent with the observed response showed in Fig 4 and 5. The calculated modal parameters are given in Table2. + +#### 3.3.3 Experimental modal analysis + +As said before, the calculation is only possible if we possess all the mechanical parameters but for larger shaker it is often impossible to block all the DOFs alternatively and to make it vibrate in order to extract the parameters. However, as presented in the theoretical review, the global mechanical parameters are equivalent to the modal ones. In [9], Guillaume presented a method for the spectral identification of modal parameters by Least Squares Complex Frequency-Domain estimation. The LMS PolyMax method is based on this method and is recognized to be very fast and accurate for modal estimation [10]. We introduced a force with an impact hammer in the two DOFs of the shaker (respectively the table and the body) and measured the acceleration of those DOFs. The LMS PolyMax method computed the transfer functions and estimated the modal parameters with the stabilization diagram presented in Figure 8. The corresponding values are given in Table 2. + +![](figure) + +![](figure) + +Fig. 8. Stabilization diagram of the impact testing on the shaker. + +When looking at these values, we may observe that the experimental values match the calculated ones for the body-related parameters, especially for the modal mass and the modal stiffness, respectively m2 and k2, and in a less manner for the modal damping c2. On the contrary, we have no match for the table-related parameters. This difference is also noticeable in Figure 8. The response curves of the body (P2-P5) clearly show a resonance, making the body-related parameters identification possible, while the table resonance, identified in the stabilization diagram to be located at 69,104Hz, is not visible (P1). We may conclude that the experimentally determined table-related parameters are not valid. diff --git a/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..01a191e47501e12d5c8896d7bb49d342a85af724 --- /dev/null +++ b/outputs/multi_column/00945e98ea0970dcffb8f548336df3a0137f_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,103 @@ +This can be explained by the relative high damping in the suspension of the coil (see Figure 5) combined with the relative small force introduced into the shaker by the impact hammer, leading to a totally damped acceleration response of the table. + +Table 2. Modal parameters + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Modal parameterSymbolValues
CalculatedDetermined experimentally
Modal mass of the vibrating tablem177.2 g18.2 g
Modal mass of the bodym23.167 kg3.33 kg
Modal damping of the suspension of the coilc115.93 kg/s1.9 kg/s
Modal damping of the isolation studsc2196.15 kg/s76 kg/s
Modal stiffness of the suspension of the coilk112.3·103 kg/s²28.02·103 kg/s²
Modal stiffness of the isolation studsk21.143·105 kg/s²1.15 ·105 kg/s²
+ +## 4 Determination of the electrical parameters + +Looking at (1) gives us the needed electrical parameters to be defined. We find R and L, the resistance and the inductance of the coil, \(\mu_{\mathrm{f}}\), the force constant, and \(\mu_{\text{bemf}}\), the bemf (back electromagnetic force) constant of the system. R and L are the intrinsic electrical properties of the coil and are purely passive. A simple measurement on the RLC meter will allow us to get those values. These are given in Table 3. The quantities \(\mu_{\mathrm{f}}and\mu_{\text{bemf}}\) are representative of the same phenomenon – the expression of the Lorentz force + +– but have neither the same causes nor the same effects. Lorentz expresses that the charge carriers of a conductor immersed in a (non-collinear) magnetic field are subjected to a force when moving and this according to the following relation: + +\[\overline{F} ^{q}q \overline{E} ^{} \overline{v} \overline{B} \] (7) + +With Fq the force exerted on a charge carrier of electrical charge q subjected to an electric field E, undergoing a speed v, and immersed in a magnetic field B. The generalized expression of this force on a conductor of length l is: + +\[FBli_{f}i\] (8) + +The current i flowing in the coil generates a force F on the latter with respect to the force constant \(\mu_{\mathrm{f}}\). The magnitude \(\mu_{\text{bemf}}\) expresses the force undergone by the electrons in a conductor which moves in a magnetic field. The displacement of the coil generates an electric potential at the conductor terminals with respect to the bemf constant. We study a system which on the one hand generates a force due to an applied current and on the other hand which creates an electrical potential with respect to the speed of the coil. This approach forms the basis of the development of a two-port network model and goes beyond the scope of this work. Different authors such as York, Smallwood or Guillaume develop this aspect deeper in detail [11–13]. + +## 4.1 Experimental determination of the force constant + +First, we used the assembly already presented in Figure 3 which blocks the vibrating table. A voltage is applied to the terminals which generates a current, which creates a force. Due to the rigid structure, the table cannot move and no bemf can settle. A measurement of the force with respect to the current yields the force constant. The latter is shown in Figure 9 for three different drive voltages. We immediately notice a very strong structural response at 660 Hz due to the resonance of the structure originally intended to be rigid. By performing a modal analysis of this structure, we obtained its frequency response. The synthesized curve has been superimposed on the measured curves to emphasize the response due to the resonance of the beam structure. + +![](figure) + +Legend: +- Drive Voltage 0.1V +- Drive Voltage 0.5V +- Drive Voltage 1V +- Synthesized FRF of the beam structure + +Axes: +- X-axis: Frequency (Hz) +- Y-axis: Frequency Transfer Function Force/Current (N/A) + +Title: Force Constant[^inferred] + +![](figure) + +Legend: +- Drive Voltage 0.1V +- Drive Voltage 0.5V +- Drive Voltage 1V +- Synthesized FRF of the beam structure + +Axes: +- X-axis: Frequency (Hz) +- Y-axis: Frequency Transfer Function Force/Current (N/A) + +Title: Force Constant[^inferred] + +Fig. 9. Force Constant analysis for different drive voltages. The synthesized FRF of the beam structure is superimposed on the measured curves to emphasize the response due to the resonance of the beam structure. + +Beyond this, the measurements tend to show an increase in damping with the drive voltage underlying a possible non-linearity of the system. At this point any deduction is dangerous and should be avoided. Further analysis is required. Nevertheless, in the area below 100 Hz, the relative theoretical error due to the resonating structure with respect to the unity does not exceed 3%. Despite a relative variation in amplitude of 5% over the frequencies, the value of \(\mu_{\mathrm{f}}\) is considered to be constant. Its average value is 7.8493 N/A against an initial value form the manufacturer of 6.4 N/A. These data are shown in Table 3. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..bac86b84a23d911a1eb3a62de8fcb299a0dc52d2 --- /dev/null +++ b/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +written records had not been taken. Recording, as discussed, was initiated on the following day. In addition, two staff members were asked to submit an estimate of the frequency of crawling on the three days preceding training. During the remainder of the study, the teachers conducted the normal program; in addition, they recorded crawling when it occurred and conducted the training procedures listed below. Three children served as subjects, one with severe and two with only moderate walking impairment. The teachers did not provide edibles or any other contrived reinforcers for walking or crawling. The procedural sequence was: restraint and priming, then, post-training. For one of the children (JL), restraint alone followed post-training. + +RESULTS + +Figure 1 presents the results of the structured study with RK, a child with severe impairment of walking. This child's crawling is presented as a percentage of the time she spent in locomotion (i.e., Time Crawling/Time Walking + Crawling × 100). The mean difference per session between the two percentage scores for the two observers was only 2.5. Similarly, the reliability of the frequency of crawling between the two observers was 99.6% per session. During the initial no-training period, the child crawled more than 80% of the time she spent in locomotion. When restraint alone was introduced, all locomotion was by crawling. Not shown in the figure is that the absolute amount of time the child spent crawling during these three sessions was less than half of the amount of time spent crawling during the first three no-training sessions. When restraint and priming was introduced, locomotion by crawling immediately decreased to about 50% and progressively decreased to nearly zero during these six sessions, totalling 60 min. It was noted during this period that the child was progressively becoming more proficient in attaining a walking posture using the chairs in the corners of the + +Fig. 1. The percentage of time in locomotion a profoundly retarded child with severe walking impairment spent by crawling. The percentage was calculated by dividing the time the child spent crawling by the time she spent walking and crawling (i.e., Crawling/Walking and Crawling) and multiplying by 100. Three 10-min sessions were scheduled daily. Restraint consisted of a teacher's restraining the child from crawling for 5 sec each time the child crawled. Priming consisted of raising the child to a walking posture each time the child crawled. Restraint and priming involved priming walking immediately after the 5-sec restraint. + +room. The child also began to offer increasing assistance during priming in attaining a walking posture. When training was discontinued (no training), crawling immediately increased to about 60%, a level substantially lower than during the initial no-training sessions. When priming-alone was introduced, crawling decreased to about 25% and continued decreasing to about 10% during the three sessions. The return to the no-training condition resulted in about 50% of the child's locomotion occurring by crawling, a lower level than during either no-training period preceding it. When restraint alone was introduced again, crawling immediately decreased to about 10%, and by the last of the three sessions was zero. During this pe- + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a112f90f99a670efb8a683892428998a8a743b2a --- /dev/null +++ b/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,19 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +ported this to be an impressive reduction. The teachers' estimate of crawling before training was 35 for CT and 15 for JR. While the restraint-priming procedure was in effect, the frequency of crawling was reduced to zero or less than once daily for both children. This low frequency of crawling was reached in about 15 days for both children and was maintained for the next 30 days while training remained in effect. When restraint and priming was discontinued (post-training), the frequency of crawling remained at zero or about once daily. + +For the children enrolled in the nursery program, walking necessarily increased as crawling decreased, since the frequency of required locomotion between rooms of the nursery program remained constant at about 25 times per day throughout the study. Since teachers never carried children, a reduction of crawling during these periods necessarily represents an increase in some alternative mode of locomotion. For these children, their only alternative was walking. + +Approximately 1.5 yr later, two of the three children were still enrolled in the nursery school program; the restraint procedure, however, had been discontinued for at least a year. The children were observed to be walking almost exclusively and staff members reported that crawling rarely occurred. For a three-day observation period, the mean number of instances of crawling per day was zero for each child. + +DISCUSSION + +The training program of restraint-for-crawling and priming-of-walking resulted in all four profoundly retarded children crawling less and walking more. This improvement occurred regardless of the child's degree of walking impairment and in a structured training situation as well as during an ongoing nursery program. During the final phases of training, the children crawled no more than once daily, or less than 10% of the time spent in locomotion, a level acceptable for children of that age. + +The training procedures should be easily administered in most settings with retarded children. No expenses for new equipment, apparatus, or reinforcers were required, but rather, the natural setting with its intrinsic reinforcers was used. The amount of staff time devoted to the training program was minimal, requiring 5 sec for restraint, and about 2 sec for priming each time a child crawled. Within one week of training, no child crawled more than seven times a day requiring, therefore, less than 1 min of staff time. After three weeks, only a few seconds were required because the children crawled less than once daily. + +Since the training program included two component procedures, restraint-for-crawling and priming-of-walking, a question remains as to whether either component alone would have produced the effect. Two lines of evidence relate to this question. The first was the use of restraint alone with the one child in the structured study. The child did decrease crawling; however, the child also ceased walking. This was not true of the combined procedure, during which walking increased as the child reduced crawling. The second line of evidence is when priming alone was used for weeks before the study. During the combined procedure, however, the children initiated walking themselves. Before the combined use of both component procedures, therefore, neither of the component procedures alone appeared sufficient. A previous attempt to train proper self-feeding to a profoundly retarded child similarly demonstrated that neither facilitation of proper skills nor the inhibition of improper responses was initially effective alone (O'Brien, Bugle, and Azrin, 1972). These results are also in accord with laboratory studies demonstrating the increased effectiveness of combined facilitation and inhibition procedures as compared with either of the component procedures, alone (Azrin and Holz, 1966; Catania, 1966; Herman and Azrin, 1964; Holz, Azrin, and Aylon, 1965). + +After restraint and priming were used in combination, restraint seemed effective alone. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..01847d24cb23533412751ad0eb33742b6de5a6bf --- /dev/null +++ b/outputs/multi_column/0097571b436308f563a5808d45d0232255a2_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,40 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +When used after the combined procedure, the child typically initiated walking, independently, immediately after she was restrained for crawling. When restraint alone was in effect, therefore, walking was pruned, albeit by the child herself. Thus, after both restraint and priming are used in combination, restraint-alone appears sufficient. + +When training was discontinued, some permanent improvement was noted for all four children. For the two children with only moderate impairment of walking, crawling remained at a level normal for children of that age. For the two children with severe impairment of walking, a degree of crawling returned that was unacceptable, even though substantially lower than before training. That the improvement was not sufficient for them suggests that the greater the degree of walking impairment, the more time need be devoted to training. Restraint was, therefore, reintroduced and the children walked rather than crawled. Even though restraint was discontinued after a few months, the children were walking almost exclusively 1.5 yr after training. + +REFERENCES + +Ayllon, T. and Azrin, N. H. Reinforcer sampling: a technique for increasing the behavior of mental patients. Journal of Applied Behavior Analysis . 1968, 1, 21-34. + +Azrin, N. H. and Holz, W. C. Punishment. In W. K. Honig, (Ed.), Operant behavior: areas of research and application . New York: Appleton-Century-Crofts, 1966. Pp. 380-448. + +Azrin, N. H. and Powell, J. A method of improving self-administration of prescribed drugs by response priming. Journal of Applied Behavior Analysis , 1969, 2, 39-43. + +Bensberg, Gerald J. Helping the retarded grow and learn. In G. Bensberg (Ed.), Teaching the mentally retarded . Atlanta, Georgia: Southern Regional Education Board, 1965, Pp. 19-39. + +Berkson, G. Psychophysiological studies in mental deficiency. In Norman R. Ellis (Ed.), Handbook of mental deficiency . New York: McGraw Hill, 1963. Pp. 556-573. + +Catania, A. C. Concurrent operants. In W. K. Honig (Ed.), Operant behavior: areas of research and application . New York: Appleton-Century-Crofts, 1966. Pp. 213-271. + +Harris, F. R., Johnston, M. K., Kelley, C. S., and Wolf, M. Effects of positive social reinforcement on regressed crawling of a nursery school child. Journal of Educational Psychology , 1964, 55, 35-41. + +Herman, R. L. and Azrin, N. H. Punishment by noise in an alternative response situation. Journal of the Experimental Analysis of Behavior . 1964, 1, 207-209. + +Holz, W. C., Azrin, N. H., and Aylon, T. Elimination of behavior of mental patients by response-produced extinction. Journal of the Experimental Analysis of Behavior , 1963, 6, 407-412. + +Loynd, J. and Barclay, A. A case study in developing ambulation in a profoundly retarded child. Behavior Research and Therapy . 1970, 8, 207. + +Malpass, L. F. Motor skills in mental deficiency. In Norman R. Ellis (Ed.), Handbook of mental deficiency . New York: McGraw Hill, 1963. Pp. 602-631. + +Meyerson, L., Kerr, N., and Michael, J. L. Behavior modification in rehabilitation. In S. W. Bijou and D. M. Baer (Eds.), Child development: readings in experimental analysis . New York: Appleton-Century-Crofts, 1967. Pp. 214-239. + +O'Brien, F., Azrin, N. H., and Henson, K. Increased communication of chronic mental patients by reinforcement and by response priming. Journal of Applied Behavior Analysis . 1969, 2, 23-31. + +O'Brien, F., Bugle, C., and Azrin, N. H. Training and maintaining a retarded child's proper eating. Journal of Applied Behavior Analysis , 1972, 5, 67-72. + +Received 16 August 1971 +(Retired 22 November 1971) + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/00d8a44d3066bbc4bd8df149d0dafb96f423_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/00d8a44d3066bbc4bd8df149d0dafb96f423_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0f762faf8f7a575de1c94e31f3cd1e28b4a6e99e --- /dev/null +++ b/outputs/multi_column/00d8a44d3066bbc4bd8df149d0dafb96f423_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,37 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +무선 PDA 기반의 원격 장치 데이터 모니터링 시스템 + +서정희** · 김길영* · 박홍복* + +*부경대학교 전자컴퓨터정보통신공학과 · **동명대학교 컴퓨터공학과 + +Remote Devices Data Monitoring System based on Wireless PDA + +Jung-hee Seo** · Kil-young Kim* · Hung-bog Park* + +†Div. of Electronic, Computer and Telecommunication Engineering, Pukyong National University + +**Dept. of Computer Engineering, Tongmyong University + +E-mail : jhseo@tu.ac.kr + +요약 + +본 논문은 PDA(Personal Digital Assistant)와 WLAN(Wireless Local Area Network) 기술을 결합한 TCP-IP 통신 기반의 원격 장치 데이터 모니터링 시스템을 제안한다. 무선의 PDA 디바이스는 서버측에서 전송되는 원격 장치의 데이터인 온도, 습도, 장치 상태 등을 연속적으로 수집하고 모바일 디바이스에 디스플레이 함으로써 무선 통신의 원격 모니터링을 위해서 사용된다. 따라서 유·무선 통합의 원격 장치 데이터 모니터링 시스템을 구축함으로써 관리자의 상황에 적용적인 데이터 수집과 장치 상태 확인의 효율성을 제공한다. + +ABSTRACT + +This paper suggests a TCP/IP-based remote data monitoring system, which combines PDA (Personal Digital Assistant) and WLAN (Wireless Local Area Network) technologies. Wireless PDA devices are used for remote monitoring of wireless communication by continuously collecting remote device data transmitted from servers such as temperature, humidity and device status, and displaying them on mobile devices. Therefore, remote data monitoring systems that integrate wireless and wired services provide data collection adaptive to administrators and efficient identification of device status. + +키워드 + +원격 장치, 모니터링, 무선 PDA, WLAN + +I. 서론 + +무선 통신 기술의 발달로 인해 PDA, 모바일 폰과 같은 다양한 디바이스와 WAN(Wireless Local Area Network) 기술과의 통합으로 이동성을 추가한 컴퓨팅 기술을 허용한다. 따라서 이런 무선 기술들은 모바일을 이용한 모니터링, 모바일 학습, 홈네트워克 등의 다양한 분야에서 활발히 연구되고 있다. 논문 [1]은 무선 PDA를 사용하여 환자들의 심장박동수, 심전도 및 SpO 2 와 같이 중 + +요한 신호를 연속적으로 수집하고 모니터링 한다. 모바일 학습은 교수법과 학습 활동의 새로운 변화로 나타나고 있으며, 전자적인 학습에서 모바일 학습(Mobile-Learning) 환경으로 변화하는 추세이다. 논문 [2]는 제어 공학 분야에서 학생들의 학습향을 목적으로 스프레드시트 기반의 비례향, 적분, 미분계수 제어 시뮬레이션 시스템을 모바일에서 개발, 구현 및 평가하였다. 그리고 개발된 모바일 스프레드시트 시스템은 대부분의 소용기기의 모바일 장치에서 작업이 가능하다. 논문 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/00d8a44d3066bbc4bd8df149d0dafb96f423_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/00d8a44d3066bbc4bd8df149d0dafb96f423_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9c5a399a5ee8917b0264f3a4ea419a392f3ce219 --- /dev/null +++ b/outputs/multi_column/00d8a44d3066bbc4bd8df149d0dafb96f423_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,27 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +데이터 수집 보드의 모델은 NI USB-6008 DAQ 보드를 사용하였다. + +2.2 클라이언트측 모듈 + +그림 2 는 PDA Unit 의 설계 구조를 나타내고 있다. 서버측에서 RS-232C 를 통해 각 장치의 데이터를 수집하고, PDA Unit 에서 무선의 TCP/IP 프로토콜을 통해서 데이터 처리 과정을 수행한다. 처리된 데이터는 실시간으로 PDA 에 디스플레이하고, 사용자는 PDA 를 통해서 각 장치에 대한 제어 명령을 서버측으로 전송한다. + +그림 6. PDA Unit 의 설계 구조 + +그림 3. 원격 장치 데이터 모니터링 수행 절차 + +따라서 클라이언트측의 PDA 장치에서 서버측의 컴퓨터에 접속하여 제어 명령을 송신하면 서버측 컴퓨터는 장치 데이터 송신 모듈을 통해서 제어 명령을 수신하고 수집한 데이터를 원격 PDA 디바이스 측으로 전송한다. 그리고 PDA 디 + +바이스에서는 장치 데이터 수신 모듈을 통해서 수신 데이터를 획득하고 PDA 디바이스에 디스플레이 한다. 따라서 원격 장치 데이터 모니터링에 대한 수행 절차를 도식화한 것은 그림 3 과 같다. + +III. 실험 결과 + +본 논문은 Windows 2000 Server 와 LabVIEW, HP iPAQ rw6100, 윈도우 포켓 PC 2003, 데이터 수집 보드인 NI USB-6008 DAQ 을 이용하여 무선 PDA 기반의 원격 장치 데이터 모니터링 시스템을 구현하였다. + +그림 8(a). 서버측 모듈 + +그림 4(b). 서버측 모듈 + +실험 결과 그림 4(a) 는 서버측의 어플리케이션으로 "원격접속주소" 인 무선의 PDA 가 접속된 상태를 나타내고, 그림 4(b) 는 PDA 어플리케이션에서 "Abort" 버튼을 선택했을 때의 상태 정보를 나타내고 있다. 그림 5(a)~그림 5(b) 는 그림 4 와 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..30e497a2d0723b6f59bc7742315d252e6f086676 --- /dev/null +++ b/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,33 @@ +![](figure) + +## POPULATIONS AT RISK ACROSS THE LIFESPAN: CASE STUDIES + +## A cross-sectional study of community-based maternal and child health interventions involving Women’s Health Volunteer Groups in rural Myanmar + +Michiko Oguro, PhD, and Shigeko Horiuchi, PhD + +Women’s Health and Midwifery, St. Luke’s International University, Tokyo, Japan + +## Correspondence to: + +Michiko Oguro, Women’s Health and Midwifery, St. Luke’s International University, 10-1 Akashi-cho, Chuo-ku, Tokyo 104-0044, Japan. E-mail: michiko-oguro@slcn.ac.jp + +# ABSTRACT + +Objective: This study identified the relationship between interventions with womens health volunteer groups in two Myanmar villages and maternal and child health outcomes. Design and Sample: This cross-sectional study included 188 women aged 15–49 years old with at least one ≤5-year-old child. The women were randomly selected from two control and two experimental villages. Measures: Data were collected via structured interview with a questionnaire based on the UNICEF Multiple Indicator Cluster Survey. Results: Logistic regression analyses confirmed that womens health volunteer group intervention was related to the participants receiving any antenatal care (OR: 6.99, p < .01) and having knowledge regarding danger signs during the perinatal period (OR: 15.08, p < .001), modern contraceptive methods (OR: 44.52, p < .001), acceptable first aid (OR: 14.04, p < .001), and malaria prevention (OR: 40.30, p < .001). A skilled midwife had the most significant relationship with patients receiving any antenatal care (OR: 65.18, p < .001). Distance from urban area negatively related to appropriate disposal of the childs stool (i.e., flushed in a latrine; OR: 7.51, p < .05). Conclusions: This study shows that womens health volunteer groups may positively affect the diffusion of the need to seek antenatal care and health knowledge in rural Myanmar. The importance of skilled midwives is also highlighted, especially in resource-limited settings. + +Key words: community-based intervention, maternal and child health, participatory approach, lay health workers, program evaluation, Myanmar. + +# Background + +Myanmar, 2012). Several reports have described + +More than 287,000 pregnant and parturient the effectiveness of community mobilization via women die every year worldwide, and most of them women’s organizations in low-resource settings, + +live in rural areas of developing countries (World Health Organization, 2012). Myanmar has a relawhere community residents act as core players in solving their own challenges (Manandhar et al., + +tively high maternal mortality rate of 140 maternal 2004; O’Rourke, Howard-Grabman, & Seoane, + +deaths per 100,000 live births in urban populations, which increases to 363 per 100,000 live births in rural populations (Ministry of Health, + +1998). These women’s group interventions use a participatory learning and action cycle guided by a facilitator, who leads a cycle of meetings to identify diff --git a/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7c8b01d371984ef935fbfebb3818eba32ea76d97 --- /dev/null +++ b/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,7 @@ +and prioritize maternal and child health challenges (Houweling et al., 2011; Morrison et al., 2010). In Myanmar, there are several reports regarding the use of lay maternal health workers, although there is great variation across programs in terms of the different societies and cultures involved (Htoo Htoo, 2010; Japanese Organization for International Cooperation in Family Planning, 2013; Mul-lany et al., 2008; Teela et al., 2009). We established women’s health volunteer groups in rural Myanmar and investigated the relationship between women’s health volunteer groups and community-based maternal and child health. + +Socio-environmental factors relevant in Myanmar. Myanmar is one of the poorest countries in Southeast Asia, with a per capita gross domestic product of \$1,105 and a poverty rate of 37.5%, one of the highest in the region (World Bank Group, 2014). Among ASEAN (Association of Southeast Asian Nations) countries, Myanmar has the second-highest infant (41 per 1,000 live births) and under-5 mortality rates (52 per 1,000 live births), prevalence of severe underweight (5.6%), and prevalence of HIV infection (0.6%) (UNICEF, 2014). In 2012, of an estimated total population of 52.8 million, 39.7 million (75%) resided in rural areas with limited access to health care services (UNFPA, 2014). The rate of antenatal care (at least four visits) in rural areas is 68% compared to 90% in urban areas. Skilled attendance at delivery is 63% in rural areas compared to 90% in urban areas; the infant mortality rate is 43 and 25 per 1,000 live births in rural and urban areas, respectively (Population Reference Bureau, 2015). Increasing access to basic health services in rural areas could have a large impact on maternal and child health. However, government expenditures on health are the lowest globally and account for only 1.3% of the total government expenditure (about US\$ 2 per person per year) (World Bank Group, 2014). Midwives play a pivotal role in improving the quality of services for pregnant women, new mothers, and newborns, especially in rural areas. The Ministry of Health, Myanmar has set a national target of at least one midwife in each village; the reality continues to lag behind the ideal. Although the youth literacy rate in Myanmar (96%) is higher than those in regional neighbors + +Cambodia (87%) and Laos (72%), as are secondary school gross enrollment rates, about 25% of students leave basic education after primary school (World Bank Group, 2014). + +Women’s group intervention. During September 2003, the Women’s Health Volunteer Group (WVG) program was introduced in two Myanmar villages to improve maternal and child health in a rural area of Meiktila Township, Mandalay Division, Myanmar, as part of a nongovernmental organization project (Oguro & Horiuchi, 2006). The two experimental villages were selected based on their distance from the nearest urban area, with experimental village 1 (E1) being relatively close to the urban area (~10 miles), and experimental village 2 (E2) being relatively far from the urban area (~22 miles). The WVGs were established by organizing women and training them using a participatory approach. Our program supported the WVGs in developing independent activities between September 2003 and March 2008. To become a WVG member, each woman had to be (a) a resident, (b) literate, (c) 18–50 years old and willing to participate in the group, (d) interested in local health and social issues, and (e) trusted by the community. The WVG members had three major responsibilities: (a) planning and managing safe maternal habits: WVG members created lists of children and pregnant mothers to receive regular checkups and immunization services, (b) implementation: WVG members mobilized pregnant mothers and children to receive antenatal care and immunization when health care workers visited the village, and (c) monitoring: WVG members monitored the mothers and children until the next immunization or childbirth. Each member was responsible for ~15 households. These criteria were selected after discussions with the village authorities. International and local facilitators visited the WVGs at least twice per month during the first year to participate in meetings and provide training and feedback. The facilitators occasionally used participatory rural appraisal tools (e.g., a resource map, seasonal calendar, and daily schedule) to guide the discussions and used storytelling to describe maternal and child health challenges. Through the meetings and training, the WVG members identified and prioritized maternal and child health issues, diff --git a/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..405dbffe500f04ccb51eaa49b006c5e65b828641 --- /dev/null +++ b/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +2008. The data collection period for analysis was from February to March 2007. + +## Measures + +Data collection. We collected data for five variables: (a) antenatal care (ANC) and childbirth care, (b) knowledge of danger signs during the perinatal period, (c) knowledge of contraception, (d) accepting first aid, and (e) health behaviors. All data were collected via structured interviews using a questionnaire, which was developed to evaluate the participants’ knowledge or awareness regarding the five variables. This questionnaire was based on the UNICEF Multiple Indicator Cluster Survey (UNICEF, 2012a,b) and also included themes regarding the country, culture, and survey goals. The validity of the questions was evaluated by two specialists in this field; consensus was used to determine which items were included in the questionnaire. The final questionnaire contained 102 questions, including 31 items regarding background characteristics, 16 items regarding ANC, 9 items regarding danger signs during the perinatal period, 10 items regarding contraception use, 3 items regarding accepting first aid, and 33 items regarding health behaviors. + +Study procedures. + +Potential participants were identified using the village map and selected via random sampling. We also recruited study collaborators, who were all graduate students at Meiktila University, which is the nearest university to the study villages. The study collaborators completed a 5-day training program that was administered by one of the authors before data collection. The training program was developed to address the questionnaire’s contents, sampling and survey implementation, communication skills, and ethical considerations. The study collaborators then visited the prospective participants, explained the aims of the study, and arranged an appointment to administer the questionnaire if the participants consented. If a participant could not complete the questionnaire due to illiteracy, the collaborator input the participant’s response on the questionnaire on her behalf after she answered verbally. All data were collected between February and March 2007; the experimental villages were evaluated before the control villages. The data were then translated from Myanmar to English by native + +Myanmar speakers who could also speak English (as indicated by a TOEFL score of 500). + +## Analytic strategy + +Data analysis. The Mann-Whitney U test, chi-square test, and Fisher’s exact test were used to compare the outcomes between the experimental and control villages. Multiple logistic regression analyses were performed to identify the relationship between the WVGs and the outcome variables. We calculated the variance inflation factor for the variables to check for collinearity before inclusion in the analyses. Differences were considered statistically significant at a p-value of <.05, and SPSS software (version 22.0; SPSS Inc., Chicago, IL, USA) was used for all analyses. + +# Results + +## Baseline characteristics + +The baseline characteristics of the villages are shown in Table 1. More than half of the women in E1 were employed in the sewing industry, while the remaining women worked as farmers. The midwife characteristics were similar for E2 and C2, although the midwife characteristics were different for E1 and C1. The midwife in village C1 had married a resident, settled with her family in the village, and lived there for 15 years. All other midwives were young and had recently been assigned to the village as their first posting (≤3 years of experience). Among the 188 participants, 38 women were from C2 (the control for E2) and 50 women were from each of the three remaining villages. Only 38 women from C2 were included because no other women fulfilled the inclusion criteria. The sociodemographic characteristics (e.g., age, education level, and economic status) were similar between the four villages. + +## Questionnaire findings + +Antenatal and childbirth care. Village C1 had a significantly higher proportion of participants who had received ANC at least once during the last pregnancy, compared to E1 (v2 = 15.17, p < .001). In contrast, E2 had a significantly higher proportion of participants who had received ANC, compared to C2 (v2 = 24.43, p < .001) (Table 2). Village C1 had a higher proportion of participants diff --git a/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e9a5c040af4526cd4ddba1f13e49b171b399a6bf --- /dev/null +++ b/outputs/multi_column/00e2c7719d58bb49fd4031cce9dcccdddec2_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,243 @@ +TABLE 2. Study Findings + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Experimental 1Control 1Experimental 2Control 2 (n = 38)
Characteristics(n = 50)(n = 50)p-value(n = 50)p-value
Antenatal and childbirth care
Any antenatal care3349<.0014718<.001
Received tetanus immunization ≥2 times during last pregnancya3350.0014729.379
Skilled attendant at last birth2045<.001812.084
Knowledge of danger signs during the perinatal period
Number of danger signs recalled, 27 items (SD)7.90 (3.07)4.70 (1.88)<.00113.92 (3.88)4.37 (2.62)<.001
Contraception
Number of modern methodsb recalled (SD)4.06 (1.37)2.82 (1.08)<.0015.16 (1.00)2.00 (0.77)<.001
First aidc
Acceptable treatment answeredd457<.001335<.001
Health behaviors
Care for sick <5-year-old child
Has your child had a fever during the last 2 weeks?517.00449.066
Did you seek advice or treatment for the illness outside of your home?113.03909.001
Has your child had a cough or difficulty breathing during the last1120.05249.066
2 weeks?
Did you seek advice or treatment for the illness outside of your home?321.00013.400
Sanitation
What was done to dispose of the stool?
Appropriate methode2622.106214.002
Inappropriate methodf391317
Number of correct precautions against malaria recalled (eight items)
Mean (SD)2.64 (0.985)1.28 (0.784)<.0012.72 (1.011)0.58 (0.522)<.001
+ +Notes. SD = standard deviation. aReceived tetanus immunization ≥2 times during last pregnancy: the purpose of giving the vaccine to pregnant women is to protect them from tetanus and to protect their newborn infants against neonatal tetanus. bModern methods: pills, hormonal injections hormonal injections that prevent pregnancy for 3 months (Depo-Provera), condoms, intrauterine device, sterilization. cFirst aid: for injuries that were sustained during agricultural work. dAcceptable treatment: wash the wound; seek care of midwife or women’s health voluntary group. eAppropriate method: flushed in a latrine. fInappropriate method: left in the open, thrown into garbage. + +treatment (applying dirt and saliva, tomato, salt, + +Health behaviors. + +# Care for sick \(\leq5-\) + +or AJINOMOTO [monosodium glutamate]) for year-old children—Compared to E1, significantly + +injuries that were sustained during agricultural + +# more children in C1 had experienced a fever during + +work. The experimental villages had a signifi- the 2-week period before questioning (v2 = 4.22, cantly higher proportion of participants who p = .004), and significantly more children in C1 answered that they received acceptable first aid were treated during their illness (v2 = 5.29, + +treatment (E1–C1: v2 = 57.85, p < .001; E2–C2: v2 = 24.57, p < .001). + +# p = .04). Although the frequency of children with fever in C2 was higher than that in E2, there were diff --git a/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_10_pg1_pg1_repeat1.md b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_10_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0aac504c1a9b50fd92c512f9d21ccc5c917d04d6 --- /dev/null +++ b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_10_pg1_pg1_repeat1.md @@ -0,0 +1,86 @@ +TABLE III. + +THE PERFORMANCE OF THE PROPOSED METHOD FOR DETECTING WHOLE MULTIMODAL VIDEO DEEPFAKES COMPARED TO RECENT STATE-OF-THE-ART METHODS ON THE FAKEAVCELEB DATASET + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
ModelBimodal
Visual video and audio
AccuracyAUCROC
Experiment 296.04%95.49%
Experiment 3 (The proposed method for the third level: whole multimodal video)97.52%97.21%
Ensemble Soft/ hard voting based VGG16 [60]78.04%78.05%
Two CNN blocks (one per modality) [60]67.4%67.2%
Xception [7]43.94%43.73%
+ +TABLE IV. + +THE GRU-BASED ATTENTION MECHANISM LAYERS DETAILS + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Layer (type)Output shapeParameters number
main_input (Input Layer)[(None, 8, 4096)]0
gru (GRU)(None, 8, 3572)82191720
attention (attention)(None, 3572)3580
Total parameters: 82,195,300
Trainable parameters: 82,202,446
Non-trainable parameters: 0
+ +The cross-entropy loss ( ) function is utilized to measure the efficiency of the suggested deepfake video detection method on three levels: video frames, audio, and the whole video. Its formula [59] is defined as follows: + +\[\sum(()()())(20)\] + +video. It can be + +where refers to the number of visual videos, audios, or whole videos. The and denote the actual label and predicted probability corresponding to the seen in Table III that the proposed method, which represents experiment 3, for whole multimodal video deepfake detection has achieved 97.52% accuracy and 97.21% AUROC. Its performance exceeds that of experiment 2 because experiment 2 is unable to learn intercorrelations between different modalities. Additionally, it outperforms recent state-of-the-art methods by an average growth of 34.4% accuracy and 34.2% AUROC as can be seen in Table III. The experiments are carried out using an OMEN HP laptop with a 16-gigabyte Intel (R) Core (TM) i7-9750H CPU, a 6gigabyte RTX 2060 GPU, and Windows 11. The proposed method is implemented using the Python programming language. Python libraries such as Keras, OpenCV, Random, Tensorflow, Numpy, OS, and Librosa are used during the implementation. The accuracy and loss curves of the proposed method on the training and validation subsets of the FakeAVCeleb dataset for the three levels; visual video frames, audio, and whole multimodal videos, are shown in Fig. 7. Additionally, the proposed method confusion matrix for deepfake video detection on the three levels is depicted in Fig. 8. Furthermore, Fig. 9 shows the receiver operating characteristic (ROC) curve and the AUROC curve of the proposed method performance. As shown in Fig. 9, the ROC curve is extremely close to the top left ensuring the high performance of the proposed method. Fig. 10 provides a comparison of the proposed method with contemporary state-of-the-art methods using evaluation metrics. As shown in Fig. 10, the proposed method has yielded better performance in comparison to the other methods on the three levels. It has a precision of 96.91%, recall of 100%, F1score of 98.43%, and specificity of 97.22% for detecting visual videos. Additionally, it has a precision of 100%, recall of 95.10%, F1-score of 97.49%, and specificity of 100% for detecting audios. Further, it has a precision of 98.43%, recall of 97.66%, F1-score of 98.04%, and specificity of 97.30% for detecting whole multimodal videos. It can be concluded that the proposed upgraded XceptionNet generated a useful spatial hierarchical representation of faces, which contributed to distinguishing between genuine and fake videos. As well, the proposed CQTbased modified InceptionResNetV2 produced a valuable deep time-frequency representation of audio. This assisted to reveal deepfake videos and improved the detection method's effectiveness. Moreover, a concatenate layer that is applied to the features extracted from visual video and audio modalities produced an informative bimodal representation of videos. In addition, the GRU-based attention mechanism, which is applied to the visual video, audio, and bimodal features, assisted in capturing the most important temporal information of videos. This in turn helped to detect the deepfakes. Furthermore, it can be inferred that correlating features from different modalities can improve the chances of achieving accurate deepfake video detection. diff --git a/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_11_pg1_pg1_repeat1.md b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_11_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2e1d359a8d039f7e65e4d50838fe5b9a3eaf5732 --- /dev/null +++ b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_11_pg1_pg1_repeat1.md @@ -0,0 +1,27 @@ +![](figure) + +![](figure) + +Fig. 7. The accuracy and loss curves of the proposed deepfake video detection method on training and validation sets. + +![](figure) + +![](figure) + +Fig. 8. The confusion matrix visualization of the proposed deepfake video detection method. + +![](figure) + +![](figure) + +Fig. 9. The ROC curve and the AUROC curve of the proposed deepfake video detection method performance. + +![](figure) + +![](figure) + +Fig. 10. The evaluation metrics of the proposed deepfake video detection method compared to recent state-of-the-art methods on the FakeAVCeleb dataset. + +## V. CONCLUSION AND FUTURE WORK + +A newly smart system for detecting video deepfakes has been presented. Two methods were proposed to extract features from visual video frames and audio modalities, respectively. These methods produced useful spatial information for visual video and valuable time-frequency information for audio, which improved the performance of the deepfake detection method. In addition, the feature representations of both modalities were passed into a mid-layer to produce an informative bimodal representation per video. It proved that using bimodal information boosts learning during training compared to the method that ignores intercorrelation between modalities. The GRU-based attention mechanism was then applied to the different feature representations to extract the most significant temporal information and detect the diff --git a/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_13_pg1_pg1_repeat1.md b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_13_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0085d6babb582e5997a6ee0970e363864c47e0dd --- /dev/null +++ b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_13_pg1_pg1_repeat1.md @@ -0,0 +1,57 @@ +[34] Wu Z, Das RK, Yang J, Li H (2020) Light convolutional neural network with feature genuinization for detection of synthetic speech attacks. arXiv preprint arXiv:2009.09637. + +[35] Bartusiak ER, Delp EJ (2021) Frequency domain-based detection of generated audio. Electronic Imaging 2021(4): 273-1-273-7. + +[36] Zhang Y, Jiang F, Duan Z (2021) One-class learning towards synthetic voice spoofing detection. IEEE Signal Processing Letters 28: 937-941. + +[37] Gomez-Alanis A, Peinado AM, Gonzalez JA, Gomez AM (2019, September) A light convolutional GRU-RNN deep feature extractor for ASV spoofing detection. In Proc. Interspeech, Vol 2019, pp 1068-1072. + +[38] Huang L, Pun CM (2020) Audio replay spoof attack detection by joint segment-based linear filter bank feature extraction and attention-enhanced DenseNet-BiLSTM network. IEEE/ACM Transactions on Audio, Speech, and Language Processing 28: 1813-1825. + +[39] Hua G, engjinteoh A, Zhang H (2021) Towards end-to-end synthetic speech detection. IEEE Signal Processing Letters. + +[40] Mittal T, Bhattacharya U, Chandra R, era A, Manocha D (2020, October) Emotions don t lie: an audio-visual deepfake detection method using affective cues. In Proceedings of the 28th A M international conference on multimedia, pp 2823-2832. + +[41] Chugh K, Gupta P, Dhall A, Subramanian R (2020, October) Not made for each other-audio-visual dissonance-based deepfake detection and localization. In Proceedings of the 28th A M International onference on Multimedia, pp 439-447. + +[42] Gu Y, Zhao X, Gong C, Yi X (2020, November) Deepfake video detection using audio-visual consistency. In International Workshop on Digital Watermarking, Springer, ham, pp 168-180. + +[43] Zhou Y, Lim SN (2021) Joint audio-visual deepfake detection. In Proceedings of the IEEE/CVF International Conference on Computer Vision, pp 14800-14809. + +[44] Gino J (2021) Audio-video deepfake detection through emotion recognition. + +[45] Mozley K (2021) Don’t believe everything you hear: combining audio and visual cues for deepfake detection. + +[46] Blankertz B (2001) The constant Q transform. URL http://doc. ml. tu-berlin. de/bbci/material/publications/Bla_constQ. Pdf. + +[47] Sch rkhuber , Klapuri A, Sontacchi A (2012, September) Pitch shifting of audio signals using the constant-q transform. In Proc. of the DAFx onference. + +[48] Todisco M, Delgado H, Evans NW (2016, June) A new feature for automatic speaker verification anti-spoofing: constant Q cepstral coefficients. In Odyssey, Vol 2016, pp 283-290. + +[49] Wang M, Wang R, Zhang XL, Rahardja S (2019, November) Hybrid constant-Q transform based CNN ensemble for acoustic scene + +classification. In 2019 Asia-pacific signal and information processing association annual summit and conference (APSIPA AS ), pp 1511-1516. + +[50] Chollet F (2017) Xception: deep learning with depthwise separable convolutions. In Proceedings of the IEEE conference on computer vision and pattern recognition, pp 1251-1258. + +[51] Ghosh S, Pal A, Jaiswal S, Santosh KC, Das N, Nasipuri M (2019) SegFast-V2: Semantic image segmentation with less parameters in deep learning for autonomous driving. International Journal of Machine Learning and Cybernetics 10(11): 3145-3154. + +[52] Szegedy , Ioffe S, Vanhoucke V, Alemi AA (2017, February) Inception-v4, inception-resnet and the impact of residual connections on learning. In Thirty-first AAAI conference on artificial intelligence. + +[53] Arfianti UI, Novitasari D R, Widodo N, Hafiyusholeh M, Utami WD (2021) Sunspot number prediction using gated recurrent unit (GRU) algorithm. IJ S (Indonesian Journal of omputing and ybernetics Systems) 15(2): 141-152. + +[54] Le XH, Ho HV, Lee G (2019, September) Application of gated recurrent unit (GRU) network for forecasting river water levels affected by tides. In International onference on Asian and Pacific oasts, Springer, Singapore, pp 673-680. + +[55] Yang Z, Yang D, Dyer C, He X, Smola A, Hovy E (2016, June) Hierarchical attention networks for document classification. In Proceedings of the 2016 conference of the North American chapter of the association for computational linguistics: human language technologies, pp 1480-1489. + +[56] Hossin M, Sulaiman MN (2015) A review on evaluation metrics for data classification evaluations. International journal of data mining & knowledge management process 5(2): 1. + +[57] Achlioptas P (2019) Stochastic gradient descent in theory and practice. + +[58] Kingma DP, Ba J (2014) Adam: a method for stochastic optimization. arXiv preprint arXiv:1412.6980. + +[59] Ho Y, Wookey S (2019) The real-world-weight cross-entropy loss function: modeling the costs of mislabeling. IEEE Access 8: 4806-4813. + +[60] Khalid H, Kim M, Tariq S, Woo SS (2021b, October) Evaluation of an audio-video multimodal deepfake dataset using unimodal and multimodal detectors. In Proceedings of the 1st workshop on synthetic multimedia-audiovisual deepfake generation and detection, pp 7-15. + +[61] Aly M, Alotaibi NS (2022) A New Model to Detect COVID-19 Coughing and Breathing Sound Symptoms Classification from CQT and Mel Spectrogram Image Representation using Deep Learning. International Journal of Advanced Computer Science and Applications, pp 601-611. diff --git a/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..134c7d64037b905d973c8bba0d7f8215a093044f --- /dev/null +++ b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,7 @@ +detect deepfake videos. The GRU performs well in tasks of sequence learning and overcomes the gradient vanishing and explosion problems of the standard recurrent neural network [16]. The proficiency of the attention mechanism has been proven in several areas including machine translations, image captioning, question answering, speech recognition [17], and event detection [18]. A comparative study with recent state-of-the-art deepfake detection methods is conducted in terms of accuracy, Area Under Receiver Operating Characteristic (AUROC) curve metric, precision, recall, F1-score, sensitivity, and specificity. The rest of this work is organized as follows: Section II presents the literature review for deepfake video detection methods. Section III presents the newly proposed method for deepfake video detection. Section IV is dedicated to the experimental results and analysis. The conclusion and future work are presented in Section V. + +# II. LITERATURE REVIEW + +The progress of AI-based video and voice generation methods raised the ease of creating natural and highly realistic deepfakes that can never be distinguished. Since deepfakes violate security and pose a real threat to society, several researchers have directed their interest to create methods for detecting deepfakes. However, they concentrate on detecting the deepfakes either in video frames or audio modality. Some of the existing deepfake visual video detection methods spot the manipulation by targeting specific spatial and temporal artifacts that are generated during the fake creation process. Some other detection methods are data-driven that do not target any specific artifacts and distinguish the manipulation by classification [3]. The deepfake visual video detection methods can be categorized into Convolution Neural Network (CNN)-based methods [19, 20, 21, 22], methods that are based on CNN with a temporal network [23, 24, 25, 26, 27], handcrafted feature-based methods [28], and handcrafted feature-based methods with deep networks [29, 30]. This is illustrated in Fig. 1. The work of [19] detected the deepfakes by exploiting artifacts left by the generation methods when warping the target image to be consistent with the source video. It used four pre-trained CNN models for detecting fake contents; ResNet101, VGG16, ResNet50, and ResNet152. Since deepfake videos suffer from inconsistency among the interframes, Hu et al. [20] introduced two branches that are based on CNNs to capture those local and global inconsistencies and then detect deepfakes. Rana and Sung [21] proposed a deep ensemble learning method for detecting deepfake videos. Their method depended on combining several deep base-learners and then training a CNN on these learners to build an ameliorated classifier. In [22], a fine-tuned InceptionResNetV2 model followed by the XGBoost model was employed to capture discrepancies in the spatial domain of fake videos and then individuate deepfakes. The FakeApp creates forged videos that had intra-frame and temporal inconsistencies between frames. + +Such inconsistencies were detected using InceptionV3 CNN and long short-term memory (LSTM) models [23]. As AI-generated fake videos lack normal eye blinking, Li et al. [24] introduced the VGG16-LSTM to capture the temporal regularities in the eye blinking process and then distinguish the deepfakes. Most deepfake videos are created frame-by-frame where each forged face is created independently. This causes incoherence in the temporal domain of the face region; discontinuity and flickering. As a result, Zheng et al. [25] introduced a fully temporal convolution network that aimed to learn the temporal discrepancies while removing spatial ones. Then, a temporal transformer encoder followed by a multilayer perceptron was employed to learn the long-range inconsistencies along the time dimension, and then distinguish the deepfakes. In [26], a 2D CNN-based Spatio-temporal learning model was introduced to learn and capture spatial and temporal inconsistencies of forged videos. This temporal inconsistency was captured from both vertical and horizontal directions over adjacent frames and helped in detecting the fakes. The work of [27] introduced a fine-tuned EfficientNetb5 model followed by the bidirectional LSTM model and densely connected layer. It aimed to discover the Spatiotemporal inconsistencies in deepfake videos and then distinguish the authenticity of videos. Deepfakes were created by joining the generated face into the source image. This produced errors in facial landmark locations that were detected by estimating the 3D head poses for real and deepfake videos. Then, the estimated difference of head poses was fed into the Support Vector Machine (SVM) for deepfake detection [28]. Khalil et al. [29] proposed a model that employed the local binary patterns descriptor to analyze the texture of real and fake videos. Additionally, a CNN-based enhanced high-resolution network was used to automatically capture informative multi-resolution representations of these videos. Then, the output of both was fed into the capsule network to individuate deepfakes. Ismail et al. [30] introduced a hybrid method in which two feature extraction methods were employed to learn and extract enrich spatial features from the detected face frames of video. These methods were a CNN that was based on the Histogram of Oriented Gradient (HOG) method and the improved XceptionNet. Their outputs were merged to be fed into GRUs sequence to extract the spatiotemporal features and detect the fake videos. The deepfake audio detection methods can be categorized into handcrafted feature-based methods [31, 32], methods that are based on low-level features with CNN [14, 33, 34, 35], methods that rely on using low-level features with CNN and temporal network [37, 38], and end-to-end deep networks-based methods [39]. This is presented in Fig. 2. The work of [31] extracted several low-level-features; Constant-Q Cepstral Coefficients (CQCC), Cepstrum, Mel-Frequency Cepstrum Coefficients (MFCC), inverted MFCC, Linear Predictive Cepstral Coefficients (LPCC), and LPCCresidual features. These features were utilized along with the Gaussian Mixture Model (GMM) to detect the forged audio. diff --git a/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..90e34353a3db40cca559d7ad890f6c0c788c8099 --- /dev/null +++ b/outputs/multi_column/00f6c2eea6b51fb1bf637b5f8a850588d7e2_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,95 @@ +3. Bimodal information-based video features: The deep extracted features from visual video frames and audio modalities using the above-mentioned unimodality-based feature extraction methods are mid-fused at a concatenate layer. This produces a feature vector representation for the whole video, which is based on bimodal information. + +4. Temporal information extraction-based attention mechanism: Most deepfake videos are generated based on synthesizing faces frame-by-frame, cloning voices, and synchronizing lips. They suffer from flickering and discontinuity of the face frames and lack of normal emotions, breathing, pauses, and the pace at which the target subject speaks among audio segments. As a result, the GRU-based attention mechanism is applied to the three levels of the extracted features independently; visual video frames, audio, and the whole video. This aims to capture the instructive temporal information that helps to differentiate real videos from fake ones. + +) and reset ( ), that modulate the information flow from + +The GRU architecture is composed of two gates; update ( the previous time step to the current step. At each time step , the update gate decides the amount of previous information that should be retained, and the reset gate determines the amount of information that needs to be forgotten [53]. The GRU hidden state at the time is defined by the following formulae [54]: + +\[\begin{aligned} ()(3) \\ () \\ ()(5) \end{aligned}\] (4) + +\[()\] (6) + +( ) represents the Hyperbolic Tangent, denotes + +where refers to the input, and and represent the weight matrices. The symbol ( ) represents the sigmoid function, the Hadamard product, and ́ denotes the candidate hidden state. As can be seen in Fig. 4, a single GRU is applied to the above-mentioned feature representations on the three levels. It produced a matrix of hidden state vectors at each time step , which represents the learned temporal information per visual video, audio, or the whole video. The hidden state vector is defined as follows: + +\[[]\] (7) + +The attention mechanism uses the weights to concentrate on the important features from the input sequence . It is defined by the following equations [17, 55]: + +\[\begin{aligned} ()) \\ () \end{aligned}\] (8) (9) + +\[\sum\] (11) + +is a result of feeding a hidden vector into a + +where single-layer Multi-Layer Perceptron (MLP) with the + +activation function. represents the weight matrix, and b refers to the bias term. The symbol represents the normalized attention weights that are produced by applying the softmax layer to . is a video representation that is formed by summing hidden vectors weighted by attention weights . + +# C. Classification + +After the instructive temporal features are produced from the GRU-based attention mechanism, a fully connected layer is used as an output layer with two classes. Softmax function is used to decide deepfake videos from real ones. The Softmax formula is defined as follows: + +\[()\sum\] (12) + +where denotes the values resulting from the output layer neurons. + +# D. Dataset + +The proposed method has been evaluated on the FakeAVCeleb multimodal videos dataset. This dataset consisted of 490 celebrity genuine videos that were selected from the VoxCeleb2 dataset based on various ethnic groups, gender, and age. Its genuine videos are face-centered and cropped. The fake videos of the FakeAVCeleb dataset were generated using DeepFaceLab, Faceswap, and FSGAN, while fake audios were generated using a real-time voice cloning tool (SV2TTS). Additionally, the Wav2Lip was applied to the deepfake videos to re-enact these videos based on the cloned audios. Thus, the FakeAVCeleb dataset had more realistic deepfakes. The FakeAVCeleb was divided into four groups; genuine visual videos with genuine audios, genuine visual videos with deepfake audios, deepfake visual videos with genuine audios, and deepfake visual videos with deepfake audios [4]. To evaluate the proposed method, 1215 genuine and deepfake videos of the FakeAVCeleb dataset are employed. These videos are divided into three subsets: training, validation, and testing. + +## IV. EXPERIMENTAL RESULTS AND ANALYSIS + +The proposed deepfake video detection method is evaluated by the FakeAVCeleb dataset. Its performance is assessed using the following evaluation metrics [56]: + +\[\int((_{()})())_{(18)}\] + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
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diff --git a/outputs/multi_column/01119fb525785eb7153ee600241ff1e01959_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/01119fb525785eb7153ee600241ff1e01959_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c3feaf20156ea3a4bc6e543243dfba597daf28dc --- /dev/null +++ b/outputs/multi_column/01119fb525785eb7153ee600241ff1e01959_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,45 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +HARVARD SCHOOL OF PUBLIC HEALTH + +Occupational Asthma and Contact Dermatitis in a Spray Painter after Introduction of an Aziridine Cross-Linker + +Christopher T. Leffler and Donald K. Milton + +Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA + +A 23-year-old spray painter developed contact dermatitis and respiratory difficulty characterized by small airways obstruction shortly after the polyfunctional aziridine cross-linker CX-100 began to be used in his workplace as a paint activator. The symptoms resolved after he was removed from the workplace and was treated with inhaled and topical steroids. Painters may have an increased risk of asthma due to exposure to a variety of agents, such as isocyanates, alkyd resins, and chromates. This case illustrates the importance of using appropriate work practices and personal protective equipment to minimize exposure. Occupational asthma is diagnosed by a history of work-related symptoms and exposure to known causative agents. The diagnosis is confirmed by serial pulmonary function testing or inhalational challenge testing. The risk of asthma attributable to occupational exposures is probably underappreciated due to underreporting and to inappropriate use of narrow definitions of exposure in epidemiologic studies of attributable risk. Key words: aziridine, contact dermatitis, occupational asthma, personal protective equipment, spray painting. Environ Health Perspect 107:599–601 (1999). [Online 16 June 1999] http://ehpnet1.niehs.nih.gov/docs/1999/107p599-601leffler/abstract.html + +Case Presentation + +A 23-year-old spray painter developed dermatitis and difficulty breathing after a new paint additive began to be used in his workplace in late December 1992. The rash began on his hands and progressed to his forearms, legs, and neck. The initial diagnosis was tinea corporis, and then astetotic dermatitis with nummular lesions. In January 1993, he was given nasal beclomethasone for congestion and an inhaler for breathing difficulties. + +In February 1993, the patient was treated for bronchitis. By March, the rash was worse and he was given an albuterol inhaler for continued wheezing. He also had several episodes of eye irritation and redness and some periorbital and unilateral facial swelling. + +During a 2-week vacation in July, the patient needed the bronchodilator less often. The rash on his hand appeared unchanged, but he noted improvement in the pruritis and in the back of his neck and legs. + +In August 1993, the patient was referred to occupational medicine for the dermatitis. He brought material safety data sheets for water-based low-bake enamel paints. The new paint additive was a polyfunctional aziridine cross-linker, CX-100 (1). At this time, the patient was using diphenhydramine, inhaled albuterol, and topical triamcinolone. He had a scaly erythematous fissured rash on the dorsum of the hands, and palmar, forearm, and + +facial erythema. An erythematous, scaly area extended over the posterior neck and upper back, and he had an intertriginous rash under the abdominal skin fold and an erythematous rash with circumscribed, raised edges on the scrotum and upper thighs. The patient's legs had erythematous papules and confluent areas of dermatitis. His nasal mucosa was boggy and pink, with a milky-colored discharge. There were bilateral expiratory wheezes throughout the lung fields, and his peak expiratory flow rate was 710 L/min. The diagnosis was a delayed hypersensitivity contact dermatitis, probably due to the aziridine cross-linker. Occupational asthma was considered because of the relation of symptoms to exposure onset and his reduced symptoms during a vacation, even if changes were not noted on weekends. + +While working, the patient's forced vital capacity (FVC) was 4.7 L (97% of predicted). His forced expiratory volume in the first second (\(FEV_{1}\)) was 3.74 L (87% of predicted). The ratio of \(FEV_{1}\) to FVC was 0.79. The patient's midexpiratory flow was 3.13 L/sec (62% of predicted). After the patient used bronchodilators, his \(FEV_{1}\) was unchanged, but the midexpiratory flow rate increased by 19%. This pattern was consistent with mild small airways disease. The patient had a 5% cross-shift drop in the peak expiratory flow rate on workdays. After + +he was removed from the workplace, the corresponding peak flow rates rose. + +By September, the patient had been out of work for 1 week. His dermatitis had improved and his lungs were clear. He then left this job permanently. + +In October, the patient was given a methacholine challenge test that showed a provocative concentration resulting in a 20% drop in the \(FEV_{1}\) (PC20) of 0.5 mg/mL (with < 8 mg/mL considered diagnostic of hyperreactive airways). The patient's dermatitis was resolved in all areas but the hands. He used a bronchodilator in the morning for chest tightness and cough and triamcinolone two puffs twice per day; he used fluocinonide cream for his hands. + +In late October, the patient was prescribed triamcinolone cream and gloves at night for a vesicular eruption on his fingers. He discontinued inhaled steroids in late 1993 because of improvement. By April 1994, the rash on the right hand had resolved, but his left hand had a small lichenified, excoriated area. He used a bronchodilator three mornings per week and after exercise. + +Past medical and occupational history. The patient denied childhood skin or respiratory problems and had never smoked. He noticed tears in his eyes when he was around cats. His identical twin got hives after bee stings. + +The patient first worked in auto shops doing body work and painting. Then, as a technical student for 2 years, he spray-painted and refinished furniture. His most recent job (for 4 years) involved spray-painting furniture on an overhead conveyor belt, wearing a solvent respirator without eye protection. He stood between the furniture and the exhaust vent when spraying the back of each piece. + +The painters added activator to the paint in a small room with a wall fan. They + +Address correspondence to D.K. Milton, 665 Huntington Avenue, Boston, MA 02115 USA. Telephone: (617) 432-3324. Fax: (617) 432-0219. E-mail: dmilton@hohp.harvard.edu + +Received 22 March 1999; accepted 22 April 1999. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0114396ecb251aa3ebaeaeaed6bd4fe50bd2_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0114396ecb251aa3ebaeaeaed6bd4fe50bd2_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..083c325d38594b90dc76dbac21b8c490efa3bdd7 --- /dev/null +++ b/outputs/multi_column/0114396ecb251aa3ebaeaeaed6bd4fe50bd2_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,5 @@ +many authors, indicates the role of psychogenic factors as a reason of infertility (14) although this hypothesis was indicated by some evidence (15). The second model emphasizes that psychological and social stress is secondary to infertility (16, 17). For many couples, infertility causes several serious social and psychological consequences such as, personal distress, reduced self-esteem and loss of correct partner relationship. These results differ in different cultures (18). For example, Turkish women often come face to face with questions such as, “Are you married? Do you have a child?”. Moreover, some Turkish people, mostly the former generations, still believe that infertility is exclusively limited to female causes. Thus, women labeled as infertile feel disgrace and fault leading to anxiety and depression. In developing countries, economic privation can arise psychological distress because many families especially in old age depend on children for sustentation (19). Besides, some infertile couples are forced to take care of their parents. Same situation can develop in the future for them. The reports regarding with infertility that associated anxiety and depression were published mostly in developed countries. Most of the studies from developing world indicated to social aspects of infertility. Moreover, a few of them provided quantitative data related to psychological disorders coexisted with infertility (20-31). Additionally, infertile women were investigated more than infertile men by these studies (21, 22, 26-30). It was reported that there is high rate of depression among infertile couples in Southern Iran (20). In the same way, a study in Kuwait shows infertile women exhibited significant higher levels of anxiety and depression, because childlessness results in social stigmatization for infertile women (21). Similar findings were found for infertile women in a Turkish study (22). However, the different outcomes were reported regarding with relationship between psychosomatic disorders and related factors in infertile couples at most of them. This study was designed to assess whether Turkish people who were suffering from couple infertility had higher levels of depression and anxiety when compared to non-infertile controls. Our secondary aim was to evaluate relationship between sociodemographic characteristics and levels of depression and anxiety in Turkish infertile couples. + +# Materials and methods + +This is a a descriptive cross sectional study conducted in a total of 248 women and 96 men with no psychiatric disturbance who were referred to Infertility Department of Ege University Medicine Faculty from March 2004 to January 2007 for treatment of their infertility problems. Inclusion criteria were diagnosis lasting a minimum of 3 months due to infertility disorders, failure to conceive despite regular sexual intercourse (4-5 times per week) sustained for a period exceeding 12 months, no contraception in the last 12 months, inability to conceive and lack of pregnancy in patient history (primary infertility). The fertile group consisted of healthy 51 women and 40 men. This group was selected from all available couples who attempting outpatient gynecological clinics of our hospital for control between the ages of 18 and 45 years, married, Turkish, having at least one child and absence of current clinical psychiatric disorders. We were dealt to equalize the infertile couples‟ and fertile couples‟ sample size because of reaching statistical adequate minimal fertile group sample size according to our primary aim of study. Then, we raised infertile sample size for our secondary aim.The subjects were informed about the aims of the study and written permission was given. A gynecologist evaluated the participants for demographic data (age, marriage duration, education, occupation, medical history, health problems, gynecological history, infertility duration and diagnosis) regarding the study and then they were visited by a psychologist to perform questionnaire scales which are The Beck Depression Inventory (BDI) (32) and the State-Trait Anxiety Inventory (STAI-S/T) (33) for the evaluation of the degree of psychopathology. We used The Turkish version of the BDI with a satisfactory validity and internal consistency (Cronbach‟s alpha:0.80) (34), a 21-item test, to assess the severity of depressive symptom. It is useable both in specific clinical populations (psychiatric) and non-specific (general population) for this purpose. Each item describes a specific behavioral manifestation of depression. A valid and reliable Turkish version of STAI-S and STAI-T (35) is another component of the research questionnaire, recommended for the evaluation of anxiety occurrence (Cronbach‟s alpha: 0.92 and 0.86, respectively). It is divided into two sections each consisting of 20 items. The first 20 items measure state anxiety (STAI-S) and the second 20 items measure trait anxiety (STAI-T). It clearly differentiates between the temporary condition of “state anxiety” and the more general and long-standing quality of “trait anxiety”. Frequency tables were formed for variables. diff --git a/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ad3222fd50e116e47d51f96a904a10eb466304c5 --- /dev/null +++ b/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,19 @@ +## Asia Pacific Journal of Multidisciplinary Research + +## Tracing Hopes of Racist-Free and Multicultural-Friendly Campuses: A Phenomenological Exploration on the Lived Experiences of Blacks in the National Capital Region Universities (Philippines) + +# Zaldy Collado (MS) + +Adamson University, Manila, Philippines zaldy.collado@adamson.edu.ph + +Date Received: February 7, 2017; Date Revised: April 27, 2017 + +Vol. 5 No.2, 156-162 May 2017 P-ISSN 2350-7756 E-ISSN 2350-8442 www.apjmr.com + +Abstract - In the Philippine campuses nowadays, the presence of foreign students is a common sight, making our academic communities one of the most culturally diverse universities in the world. This requires us to provide necessary local environment appropriate and ready to attend to multicultural sensitivities. Thus the research aimed to look at how well-prepared Philippine universities are in terms of having multi-cultural friendly campuses. Through in-depth interviews and phenomenological method, the researcher explored the lived experiences of Black African students in their respective campuses. The results showed that (a) the participants’ decision to study in the Philippines was based on factors such as the hassle-less application process, cheaper yet of quality education and the image of Filipinos as being friendly and kind (b) the common, though very light, concern was not racism nor discrimination, but speaking in the local language in their presence made them feel sometimes isolated or insulted and (c) that racism and discrimination against blacks were not an institutional reality, though unfriendly encounters with Filipinos were also recorded, those were not seen as serious cases of racist behavior. The study suggested that since blacks’ experiences are generally devoid of racism and discrimination, school administrations do not tend to formulate explicit policies and enough activities to ensure racist-free campuses and inter-cultural inclusiveness among Filipinos and the blacks. In any case, the black students were determined to obtain their degrees here no matter what and such a goal was made easier because of the kind of tertiary academic communities their respective schools offer. + +## Keywords–Black Africans, Philippine Universities, Racism + +## INTRODUCTION + +Philippine educational institutions have been marked by an increase in the number of foreign students seeking Philippine diploma. According to Bureau of Immigration Statistics, from 21,000 in 2011, the number has tripled in 2012, accounting 61,000 foreign students in that year. This sudden surge of international students is attributed to the rising tide of schools which are allowed by the government to admit international students, which from 104 schools in 2011, have ballooned into 2,145 in 2012. Thus, foreign students walking around Philippine campuses are now a common sight, making our academic communities one of the most culturally diverse universities in the world. This, in turn, requires us to provide necessary local environment appropriate and ready to attend to multicultural sensitivities. But are our campuses really prepared to accept foreign students, especially blacks, into the arena of social relationships without discrimination issues? It is for this reason that the researcher has conducted this study. Campus racial discrimination seems to be a perplexing social issue in the academic settings and environments. From different universities and colleges (and in the level of governments), the fight against this social pathology is continuing and must not stop to ensure further its total eradication in the future and for future generations. The academic communities of tertiary education, from its teaching and non-teaching personnel, must be responsible enough to pin point sources of racial discrimination in the institutional and interpersonal levels and help them gradually eliminate this social issue through a united effort and various diff --git a/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7c82da291f7176739ab1c47c4c12a8617e64ad1d --- /dev/null +++ b/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +respective universities. Since it was not easy to just talk or contact any black African, the researcher used the snowball sampling technique wherein those who were first identified as participants were asked to suggest any of their friends who could also be part of the study. The researcher assured the co-researchers (participants) of the confidentiality of the study, telling them that no part of the research or of the interviews would be directly attributable to any of them. These interviews were conducted in locations near or in the places of residence of the co-researchers or also in places they chose for reasons of comfortability or also in the places suggested by the researcher himself. + +# RESULTS + +After the in-depth interviews conducted, these several themes emerged as the recurring themes, purporting how the foreign students see the Philippine campuses as higher learning institutions (HEIs) and as a social environment. These themes are supported by some quotes from the narratives below. + +1. Philippine Higher Educational Institutions + +are preferred. Blacks favor Philippine schools over other potential academic destinations. Considerations range from the high quality of education, minimal cost, simpler admission policies and the friendly and undiscriminating kind of the Filipino people. + +―Deciding to study abroad is a kind of a complicated issue back in Nigeria. Because in Nigeria the academic system is quite different from here, especially in the Philippines. It's quite easier here, the academic system. In Nigeria, we have to go series of screen examinations before we can go into the higher institution. While here, it’s just one exam or at most two exams.‖ ―I have a friend who studied in Batangas in Lyceum. Actually he graduated now, basically he said the system was, you know, pretty smooth and fast, there were no strikes, the tuition was affordable, even though not too cheap, it’s affordable and then you could transfer schools if you wanted to and then you have a choice of doing whatever course you wanna do and back in Nigeria I wasn’t so flexible, I was a bit rigid, getting admission was kinda difficult and then tuition was a bit higher so Philippines was so, you know, like a good choice after all those‖ + +―I had higher expectations that the universities here would be like better than the ones in our country in my country, would be good in education and something to learn. I have to say that some of the expectations were meet, the University reached the expectations I had.‖ ―I choose Philippines because first of all Philippines is an English education system, they use English. Secondly, it is cheaper because compared to other countries like China, Europe and US, it’s affordable for my parents, so that I can stay here. It's cheaper and they use English as a system of language in education.‖ ―When you are coming from Africa to countries like Philippines, you don't know. It is said that people will be racist, that's what you expect but when I go here I didn't, I have never experience it today in my school and it’s a very good thing and I'm happy that's why I feel like it’s a good country and you feel at home. Except the language barrier everything is okay. So, I think Philippines is a good country for black Africans to study in.‖ The language barrier is a real concern. Though blacks admit that speaking in our local language seems to be inevitable, they express concern about not being able to understand instructions and small talks in Tagalog, whether in class hours or not, and interpret those as somewhat offending and unfriendly though not really seen as strictly discriminatory. ―When they start to talk then they will say, I'm shy. I feel lonely. It's like the problem of language, language barrier. Sometimes, I have a class like I'm the only black in the class and others are Filipinos. Sometimes, the teacher, to better explain it they speak in Tagalog and I don't know anything about Tagalog so I feel like I am not welcome. The teacher is in the front he/she speaking Tagalog and you ate in the class and speaks like for, if I have a class for one hour he/she speaks in Tagalog for thirty minutes, it’s like what are we doing here, because we're like apart. ―So I really don’t know, but sometimes they really gossip about you in Tagalog, just for the few I understand, they talk about you, you would just hear your last name, I just hear my last name, Payube, but when I’m staring, they will not say anything.‖ ―I also felt and experienced that some are unfriendly to me, inside the campus I came across in situation like that because Philippines, most of the students in FEU they communicate in Filipino language, Tagalog. I’m not so fluent in understanding Tagalog but I try to understand their actions. I try to diff --git a/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f3315b8229c70c625eca692c343f9c2de1de15d1 --- /dev/null +++ b/outputs/multi_column/013a3686ef75b4150c07d3ebc510ca2455d6_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,9 @@ +tertiary educational communities as multi-cultural sensitive and friendly campuses. If there is any, the blacks’ recurring concern lies in the problem of language that serves as barriers for a more open and constructive communication between them and the Filipinos. Color is not the problem, it is the language. At times, blacks may feel annoyed and insulted when Filipinos speak in Tagalog in their presence depending in the circumstances in which Filipinos do not necessarily intend to. Blacks consider this language barrier a legitimate concern to be addressed, a problem so counterproductive to our aim of becoming truly prepared to accept foreigners in our academic communities. Nonetheless, with the right amount of determination and focus, blacks are confident to finish their studies here. This is actually made easy because people that surround them in the campus are generally seen as helpful individuals who are always ready to assist them. They maintain that with that positive attitude and the Philippine schools’ physical, academic and social preparedness to provide learning environment conducive for multi-cultural sensitivities and needs, they can be successful in the future as holders of Philippine diplomas. The absence or lack of concrete activities and policies to further promote inclusiveness and friendliness between Africans and Filipinos are obviously not a priority of Philippine tertiary schools. Though their establishment could have advantageous impacts in the academic communities (as the cited related literatures would say), those are not seen as necessary. + +## Theorizing from Experience (with recommendations) + +Countries with ―questionable‖ quality of education and difficult tertiary admission system drive away home grown economically capable students to study abroad. Destinations in this regard point out to countries with quality education and easier admission process and affordable fees. This makes the Philippines a top contender and a logical choice. As foreigners or blacks continue to flock here for purposes of getting tertiary education, the Philippines would have to expect more and more aliens to study here in the next years to come. If there is one thing which is clear in this scenario, it is the foreigners’ assumption that our higher learning institutions are up to their standards and that their expectations would be fulfilled. + +## RECOMMENDATIONS + +The Philippines must maintain and work out further advancement of quality of education in order to ensure influx of foreign students that seek affordable but good education away from their home country if such a goal is of our national interest. We must also further formulate measures that allow easier access to Philippine education by foreigners but without compromising academic quality and security. This is to secure our spot in the most visited schools in Asia as we introduce and showcase the quality of 21st Philippine tertiary education. Language barrier is a problematic factor of Filipino-blacks relations in the campus. Though not really alarming in the sense that blacks would get out of the country, speaking in the local language has been expressed by blacks with a serious tone which at times could be interpreted in a very negative light. The schools, its students and academic staff, must acknowledge and understand the negative sentiments of blacks (foreigners) regarding speaking in Tagalog in some circumstances. To avoid miscalculations and frictions between locals and blacks, the school administration has to do something in order to ensure that every encounter between locals and foreigners is a potential encounter for friendship and inclusiveness. Instituting concrete activities and explicit policies that convey and promote social harmony and interracial integration to diminish or eradicate racism or discrimination in the campus is not seen as a priority in the Philippine tertiary educational system. This is because there is no racial discrimination to begin with. The blacks themselves deny being discriminated on account of their color so nobody in the black community complains about it, the schools find it unnecessary to provide and initiate concrete programs and explicit policies that allow more avenues for bonding and recognition between the locals and the blacks. This is a policy of complacency. Our schools must not remain satisfied in the current social attitude towards the blacks in the campuses and indeed must introduce certain specific activities and policies to advance further inclusiveness among studentry of diverse racial backgrounds. While it is true that there is neither institutional discrimination nor widespread racism in the campus, our schools must not adapt the policy of complacency with regard to this matter. For one, schools must deny any possibility that ignorance to others’ racial and cultural background may lead to racist remarks from local students as our schools must attend responsibly diff --git a/outputs/multi_column/0145bc47f7ca5f8c5ff1a10481207670bcd3_page_11_pg1_pg1_repeat1.md b/outputs/multi_column/0145bc47f7ca5f8c5ff1a10481207670bcd3_page_11_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2b65d40e29f07218e4c36491dc3764f49497e937 --- /dev/null +++ b/outputs/multi_column/0145bc47f7ca5f8c5ff1a10481207670bcd3_page_11_pg1_pg1_repeat1.md @@ -0,0 +1,59 @@ +# KIN 755 Exercise Electrocardiography, Testing, and Prescription (Units: 3) + +Prerequisite: Restricted to graduate Kinesiology students or permission of the instructor. + +In-depth theoretical background for exercise, electrocardiography, testing, and prescription for individuals and groups in clinical, corporate, community, and occupational settings. (Plus-minus letter grade only) + +## KIN 763 Motivation and Performance (Units: 3) + +Prerequisite: Restricted to graduate Kinesiology students or permission of the instructor. + +Psychological perspectives of human performance and research findings in the areas of sport and exercise psychology. Awareness of literature focused on the psychological dimension. (Plus-minus letter grade only) + +## KIN 766 Sociocultural Bases of Physical Activity (Units: 3) + +Prerequisite: Graduate standing or permission of the instructor. + +Sociocultural factors underlying participation in physical activity, sport, and exercise. Implications for the practitioner. + +## KIN 781 Muscle Physiology (Units: 3) + +Prerequisite: Restricted to graduate Kinesiology students or permission of the instructor. + +Basic and applied physiological properties of skeletal muscles (from the molecular to whole muscle level), in the context of the physiological adaptations from disuse, injury, and training. (Plus-minus letter grade only) [Formerly paired with KIN 681] + +## KIN 795 Seminar in Kinesiology (Units: 3) + +Prerequisites: KIN 710 and KIN 715; 15 units towards advancement to candidacy (ATC). + +Interdisciplinary seminar on relevant kinesiology issues, areas of interest, problems, and future directions. Involves extensive analysis of recent and significant research. (Plus-minus letter grade only) + +## KIN 895 Master's Project in Kinesiology (Units: 3) + +Prerequisites: Completion of core and concentration requirements; permission of the instructor and approval of Advancement to Candidacy (ATC) and Culminating Experience (CE) forms by Graduate Studies. + +Development of a research question on a topic approved by faculty with literature review, methodology and statistical analysis. Includes proposal and oral presentation. Advancement to Candidacy and Proposal for Culminating Experience Requirement must be approved by Graduate Studies before registration. (CR/NC grading only) + +## KIN 896 Directed Reading in Kinesiology (Units: 3) + +Prerequisites: 21 units towards Advancement to Candidacy; permission of the adviser and instructor. + +Integrating information in movement and exercise science or a significant issue. May be repeated once for a total of 6 units. + +## KIN 897 Independent Research in Kinesiology (Units: 3) + +Prerequisites: KIN 710 and KIN 715 or equivalent; 12 graduate units towards Advancement to Candidacy; and permission of the graduate adviser. + +Independent, original research investigation supervised by a graduate adviser. For students who selected the thesis culminating experience. (CR/NC grading only) + +# KIN 898 Master's Thesis (Units: 3) + +Prerequisites: Graduate Kinesiology students; KIN 897; and permission of the graduate major adviser and instructor; and approval of Advancement to Candidacy (ATC) and Culminating Experience (CE) forms by Graduate Studies. Advancement to Candidacy and Proposal for Culminating Experience Requirement forms must be approved by the Graduate Division before registration. + +## (CR/NC grading only) + +# KIN 899 Independent Study (Units: 1-3) + +Prerequisites: Graduate standing with demonstrated ability to do independent work and permission of the adviser and supervising instructor. + +Independent study or research is planned, developed, and completed under the direction of a faculty member. May be repeated for a total of six units. (CR/NC grading only) diff --git a/outputs/multi_column/0145bc47f7ca5f8c5ff1a10481207670bcd3_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0145bc47f7ca5f8c5ff1a10481207670bcd3_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..46e3e79ee7e75884fc38fa6e50523396fd7844f3 --- /dev/null +++ b/outputs/multi_column/0145bc47f7ca5f8c5ff1a10481207670bcd3_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,50 @@ +# KINESIOLOGY + +# College of Health and Social Sciences + +Interim Dean: Dr. Andreana Clay + +#### Department of Kinesiology + +GYM 101 Phone: (415) 338-2244 Fax: (415) 338-7566 Chair: Matt Lee Graduate Program Coordinator: Maria Veri + +# Program Scope + +The programs in Kinesiology at San Francisco State University are carefully designed so that students experience the multidisciplinary foundations of human movement and physical activity. Students gain theoretical and practical knowledge related to the biological, physical, behavioral, sociocultural, philosophical, and psychological factors underlying human movement and physical activity. The field of kinesiology studies underlying factors in the context of skill in a variety of contexts, including those related to activities of daily living, work settings, recreation, sport, and the performing arts. Factors and parameters associated with conditioning, learning, and rehabilitation are studied across the lifespan and within a diversity of populations. In addition, sport is studied as a personal endeavor and social institution. Thematic emphases allow students to select patterns of courses tailored to meet individual interests and career goals. + +The department offers a wide array of physical activity classes that provide instruction in movement and sport skills from beginning to advanced levels; an array of General Education courses examining aspects of physical activity and mental-physical performance from various perspectives; prerequisites for advanced graduate study and certificates in therapeutic and allied health fields and adapted physical education; and minors leading to certification in coaching and adapted physical education. + +# Physical Education and Adapted Physical Education Teaching + +Students who wish to become credentialed as public school teachers in physical education or as adapted physical education specialists should select the Integrated Teacher Education Program (ITEP) in Physical Education c (http://bulletin.sfsu.edu/colleges/health-social-sciences/kinesiology/bs-kinesiology-concentration-physical-education/ #degreerequirementstext)oncentration. However, to be eligible for admission to the credential program at San Francisco State, students must attain a GPA of 2.75 or better in the Subject Matter Program curriculum. Students must work closely with an advisor to fulfill the requirements of the Subject Matter Program, and should also contact the Credential and Graduate Services Center for teaching credential information. The Center is located in Burk Hall 244, (415) 405-3594; credinfo@sfsu.edu. + +# Adapted Physical Education (Added Authorization) + +The Adapted Physical Education Added Authorization (APE AA) allows an individual to teach special needs students who are precluded from participating in a general education physical education program or a specially designed physical education program as determined by the local level special education assessment. The APE Added Authorization is an add-on authorization for the holder of a valid prerequisite credential. + +Candidates for the Add Authorization in Adapted Physical Education must hold a teaching credential in one of the following: Physical Education Single Subject, Multiple Subject, or Special Education – with 12 units of prerequisites that include the following coursework or equivalent: + +| Code | Title | Units | +| --- | --- | --- | +| KIN 487 | Motor Development | 3 | +| KIN 485 | Biomechanics | 3 | +| KIN 580 | Middle and High School Physical Education: Grades 6-12 | 3 | +| KIN 581 | Practicum in Middle and High School Physical | 1 | +| | Education | | +| | An instructional analysis upon the advisor’s approval | 2 | + +# Bachelor of Science: Exercise and Movement Sciences + +The concentration in Exercise & Movement Sciences serves students interested in biomechanics, exercise physiology, motor control, motor learning and development, sport and exercise psychology, sport history, sport sociology, at-risk youth development, and physical or occupational therapy. + +#### Focus Areas: + +Movement Science: Study of human movement from the perspective of the mover/performer (the status of performer, their abilities and characteristics), the task, what the mover is trying to accomplish (the goal of the movement or task and expected outcome), and the environmental conditions in which the task is performed. + +Exercise Science: Study of human movement from the physiological perspective including understanding the factors that influence work performance, training programs, adaptations including the reduction of risk factor for medical conditions such as coronary heart disease, cerebral vascular disease, adult-onset diabetes, obesity, and osteoporosis, as well as special conditions such as pregnancy and thither hypokinetic illness, or adaptations that are effective for youth, aged, and disabled populations. + +Social Science: Study of physical activity using theoretical and methodological approaches from sociology, history, cultural studies, pedagogy, psychology, youth development, and philosophy focusing on the context in which the activity occurs. Supports an understanding of the meanings and experiences of all forms of human physical activity for individuals and groups across the lifespan, from children and youth to older individuals across all forms of physical activity. + +# Minor in Athletic Coaching + +This area of study provides students in academic areas other than kinesiology with the knowledge and skills required for coaching interscholastic or community athletic teams. diff --git a/outputs/multi_column/0145cc39b04386db908f8d5f080137c91a6e_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0145cc39b04386db908f8d5f080137c91a6e_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8f9f13887f13f60c5c8f5386cf0a6e892238bf40 --- /dev/null +++ b/outputs/multi_column/0145cc39b04386db908f8d5f080137c91a6e_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +# Mode Softening, Ferroelectric Transition, and Tunable Photonic Band Structures in a Point-Dipole Crystal + +## J. A. Klugkist, M. Mostovoy, and J. Knoester + +Institute for Theoretical Physics and Materials Science Center, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands (Received 15 December 2005; published 27 April 2006) We study the photonic band structure of cubic crystals of point dipoles. It is shown that in contrast to earlier claims these systems cannot have an omnidirectional photonic band gap. For sufficiently large plasma frequencies, however, they exhibit softening of photonic bands, leading to (anti)ferroelectric ordering of the dipoles and the possibility to open and tune directional band gaps by external electric fields. The model studied may be realized through lattices of quantum dots. + +DOI: 10.1103/PhysRevLett.96.163903 + +The study of wave propagation through a periodic structure has had a long history, and still plays an important role in condensed matter physics. A conceptually simple example with a rich variety of physical properties is the propagation of electromagnetic waves through crystals of point dipoles. The oldest use of this model is the concept of the polariton and the polariton stop gap, describing the optical modes in atomic and molecular crystals [1,2]. More recently, crystals of point dipoles have also been used to model the propagation of light through photonic crystals. These are materials in which the refractive index is modulated with a period of the order of the wavelength of light. The multiple scattering in these crystals gives rise to the opening of photonic band gaps [3,4], in analogy to the electronic band gaps in semiconductors; photonic band gaps have been reproduced using lattices of point dipoles [5]. Photonic band gaps have interesting fundamental and technological consequences, such as the possibility to modify spontaneous emission [6], and the development of perfect mirrors and novel wave guides [7]. Other intriguing phenomena that have been predicted for point-dipole crystals are a negative refractive index and subwavelength lensing [8]. Recent advances in the fabrication of semiconductor and metallic quantum dots have opened new possibilities to realize materials that are well represented as crystals of point dipoles. The Mie or plasma resonances of the individual dots act as the dipolar transitions, with a wavelength much larger than the dot size [9]. It has been realized that arrays of closely spaced quantum dots, considered as point dipoles, may be used as subwavelength guides for electromagnetic energy (plasmonics) [10,11]. It has also been suggested that quantum dots forming two-dimensional lattices may spontaneously polarize as a consequence of the interdot dipolar interactions, even for lattice constants of the order of 100 nm [12]. Combining several of the above concepts, one may envision photonic crystals whose band structures soften as a consequence of electromagnetic interactions between + +PACS numbers: 42.70.Qs, 71.36.+c, 73.20.Mf, \(77.80.-e\) + +unit cells, leading to a dipole-ordered state at some critical interaction strength. Close to this instability, the band structure is expected to be very sensitive to external electric fields. This opens the possibility to tune photonic band gaps, a highly desired feature in photonics, for which several alternative methods have been suggested [13–18]. In this Letter, motivated by the above ideas, we perform a detailed study of the photonic band structure of cubic (sc, fcc, and bcc) point-dipole crystals. The dipole-light interaction couples the dipole excitations with a crystal wave vector \(k\) to photons with wave vectors \(kG,\text{where}G\) is an arbitrary vector of the reciprocal lattice. This coupling, on the one hand, gives rise to the photonic bands and, on the other hand, results in long-range (retarded) interactions between the dipoles. We show that, in contrast to earlier claims [5], omnidirectional gaps do not occur in the band structure of these lattices. We also show that for sufficiently strong interactions the lowest photonic bands may soften at a particular symmetry point of the Brillouin zone, which leads to a dipole-ordered state, and we demonstrate the opening and tunability of directional band gaps when switching external electric fields close to the transition to this ordered state. We consider a periodic array of transition dipoles, treated as harmonic oscillators with a frequency !0, coupled linearly to the electromagnetic field. The Lagrangian reads (cf. Ref. [1]) + +\[\begin{aligned} L^{Z}dV^{} \frac{E^{2}-H^{2}}{8} A^{0}r-P \frac{A}{c} -P\_^{} \\ \frac{2n}{!_{p}^{2}} X_{j}p\__{j}^{2}-!_{0}^{2}p_{j}^{2}: \end{aligned}\] (1) + +Here the plasmon frequency \(!_{p}\) plays the role of a coupling constant, \(n\) is the density of dipoles and the polarization density is given by \(Pt;x^{P_{j}}p_{j}tx-R_{j}\), where \(R_{j}\) are the coordinates of the lattice sites. Imposing the Coulomb gauge \(r-A0\) and eliminating \(A^{0}\), we obtain diff --git a/outputs/multi_column/01460d3dc3eca92c0d1a17eff846fa682f3d_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/01460d3dc3eca92c0d1a17eff846fa682f3d_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..12bdeb67ca247160a92b611673702566dfa4a525 --- /dev/null +++ b/outputs/multi_column/01460d3dc3eca92c0d1a17eff846fa682f3d_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,137 @@ +c1 c1 + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +v5 v5 + +![](figure) + +c2c c2c + +v1 v2 v3 v1 v2 v3 + +1 + +v4 v4 + +v6 v6 + +v7 v7 + +v8 v9 v8 v9 + +c3 c3 + +(a) + +(b) + +![](figure) + +Fig. 5. The network nodes are partitioned into cluster \(c_{1},c_{2}\text{and}c_{3}\). (a) The nodes \(\{v_{2},v_{3},v_{4},v_{5}\}\) are the border nodes of cluster \(c_{1}\) after Step II of Section III-B3b. (b) Node \(v_{1}\) replaces \(v_{2}\text{and}v_{3}\) as the border node. + +## Algorithm 2: Reduce Redundant Border Nodes + +1 for Each cluster \(c_{i}\) do + +2 + +Set cluster weight as \(1/(|b_{i}\cup\beta_{i}|)\). + +3 Calculate MVC on cluster-level topology. + +4 if Border node in non-VC cluster then + +Change to the cluster-ID of neighbor VC cluster. + +5 + +6 Calculate MVC on \(b_{i}^{m}\cup\delta_{i}^{m}\text{as}\lambda_{i}\). + +7 Select \(\text{Min}\{|b_{i}^{m}|,|\lambda_{i}|\}\) as the border nodes of \(c_{i}^{m}\) . + +\(c_{2}\) are \(\{v_{3},v_{5},v_{8},v_{9}\}\), and the cluster border nodes between \(c_{1}\text{and}c_{3}\) are \(\{v_{2},v_{3},v_{4},v_{6},v_{7}\}\). Secondly, the intersection \(\{v_{2},v_{3},v_{4},v_{5}\}\). Although we select the minimum number of + +area between \(c_{1}^{2}\text{and}c_{1}^{3}\) becomes cluster \(c_{1}\) with border nodes + +border nodes for \(c_{1}^{2}\text{and}c_{1}^{3},v_{1}\) can replace \(v_{2}\text{and}v_{3}\) as the border node of \(c_{1}\) as shown in Fig. 5(b) to further decrease the total number of border nodes. We formalize the approach to reduce redundant border nodes as follows. The main operation flow is shown in Alg. 2. (i) We reset the cluster-ID of all the border nodes selected in Section III-B3b to a minimum number of clusters. We convert it to the Minimum Vertex Cover (MVC) problem [12] as follows. In the first place, we abstract the clusters into a cluster-level topology as shown in Fig. 6, where each cluster-level node represents a cluster. If there exists edges between two clusters as in Fig. 6.(a), we connect the two cluster-level nodes. Next, we set the weight of each node in the cluster-level topology. The border nodes in cluster \(c_{i}\) are \(b_{i}\) after Alg. 1, and we call all the other border nodes that have edge connections with cluster \(c_{i}\text{as}\beta_{i}\). The nodes set \(b_{i}\cup\beta_{i}\) represents the maximum set of border nodes in \(c_{i}\) if re-categorizing the cluster-ID of \(\beta_{i}\). To concentrate more border nodes in fewer clusters using MVC, we set weight value to each cluster. If the number of all the possible border nodes \(|b_{i}\cup\beta_{i}|\) is high, we set a low weight value to the cluster \(c_{i}\). In the implementation, we set the weight of cluster \(c_{i}\) to \(1/(|b_{i}\cup\beta_{i}|)\). After that, we run the MVC algorithm on the cluster-level topology. If a border node belongs to a non-VC cluster, it changes its cluster-ID to the neighbor VC cluster. To differentiate with the notations before this step, \(c_{i}\) changes to \(c_{i}^{m}\) after re-categorizing the border nodes, and \(b_{i}\) changes to \(b_{i}^{m}\) . + +(ii) Name \(\delta_{i}^{m}\) as the subset of \(c_{i}^{m}-b_{i}^{m}\) , in which each node + +![](figure) + +C1 C5 + +C1 + +C3 + +C3 + +C2 + +C4 + +C4 + +C2 + +C5 + +C6 + +C6 + +C7 + +C7 + +C9 + +C8 + +C8 + +C9 + +C10 + +C11 + +C12 + +C11 + +C10 + +C12 + +(a) + +(b) + +![](figure) + +Fig. 6. (a) The network nodes are partitioned into clusters with different colors. (b) The clusters are abstracted into a cluster-level topology. The nodes in solid blue are vertex cover clusters. + +has at least a neighbor in \(b_{i}^{m}\) . To simplify the analysis, we suppose there are not sink nodes at \(b_{i}^{m}\text{or}\delta_{i}^{m}\) . The nodes in \(b_{i}^{m}\text{and}\delta_{i}^{m}\) are not in cluster-contained-subnets. Name \(\Phi_{i}= b_{i}^{m}\cup\delta_{i}^{m}\) . Fig. 5(a) illustrates the example \(\Phi_{1}\) of \(c_{1}\). Then we calculate MVC on \(\Phi_{i}\text{as}\lambda_{i}\). We use \(\lambda_{i}\) as alternative border nodes to \(b_{i}^{m}\) . Because each edge in \(\Phi_{i}\) has at least one endpoint in the MVC nodes \(\lambda_{i}\), so monitoring \(\lambda_{i}\) can capture all the flows passing over \(\Phi_{i}\). The number of \(\lambda_{i}\) is not necessarily smaller than \(b_{i}^{m}\) . Therefore, we select \(\text{Min}\{|b_{i}^{m}|,|\lambda_{i}|\}\) as the new border nodes of \(c_{i}^{m}\) . If \(\lambda_{i}\) are selected as the border nodes of cluster \(c_{i}^{m}\) , the non-VC nodes in \(b_{i}^{m}\) do not need to monitor the flow, and their cluster-ID are set to the neighbor cluster. + +## C. Protocol for Cluster based SD-WSN + +CluFlow makes the SDN controller estimate flow among clusters by monitoring the flow at border nodes. The SDN controller controls traffic flow by injecting cluster-level routing rules to the border nodes. The management procedure of the SDN controller and nodes in WSN is shown in Alg. 3. There are at least two benefits of utilizing SDN control in cluster-level routing. Firstly, compared with SDN management for every node in WSN, CluFlow trades granularity of SDN control for less communication load. Only cluster border nodes communicate with the SDN controller. The number of nodes that communicate with the SDN controller decreases. Secondly, cluster-level routing and local routing are decoupled. The nodes inside the clusters use only distributed local routing and do not need to request flow table entries from the SDN controller. The communication delay caused by requesting flow table entries therefore decreases. + +## IV. EXPERIMENTAL SETUP AND RESULTS + +In this section, we test and evaluate CluFlow in simulation and a real deployed WSN. + +## A. Benchmark Approaches + +To evaluate the performance of CluFlow, three benchmark approaches are implemented to calculate the communication flow among clusters. diff --git a/outputs/multi_column/01460d3dc3eca92c0d1a17eff846fa682f3d_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/01460d3dc3eca92c0d1a17eff846fa682f3d_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..43cd1edfa2b79fb3e9da09dd39130674d0fc419b --- /dev/null +++ b/outputs/multi_column/01460d3dc3eca92c0d1a17eff846fa682f3d_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,55 @@ +The load size of each packet is 64 bytes. The experiment lasts for 600 seconds using CluFlow and each benchmark approach. We count the number of cluster border nodes and the communication cost, i.e., the number of sent and forwarded IP packets in the border nodes. The results are shown in Fig. 11. Compared with the benchmark approaches, CluFlow utilizes the smallest number of border nodes and communication cost. + +## V. RELATED WORK + +Most existing WSN structures utilize a distributed control system. They are facing the same difficulties as traditional wired networks. Existing WSN management does not provide high-level abstraction. Dynamically changing control policy in WSN becomes increasingly difficult as the scale of WSN increases [6]. The research in [15] provides a solution to utilize OpenFlow in wireless networks. It uses the OpenFlow centralized controller for routing data traffic. SDN-WISE [16] designs and implements a complete SDN system in a real multi-hop wireless network. Its SDN components consist of SDN controller, topology manager, protocol stacks, and wireless motes. It provides a stateful solution and reduces the amount of communication between nodes and SDN controllers. The research in [17] creates an SDN framework for IoT systems based on SDN-WISE and Open Network Operating System (ONOS) [18]. To connect IoT and SDN, it extends the functionality of ONOS as the controller in WSN, while the communication protocol relies on SDN-WISE. In these frameworks, the SDN controller must rely on distributed routing to setup control flow in the nodes that are several hops away. To update flow table entries, the nodes and the SDN controller have to exchange request and reply messages over multiple hops periodically. This process causes much communication delay and overhead in wireless networks. Some researches focus on increasing the performance of WSN, such as energy efficiency, task scheduling, routing, etc., using SDN structure. SDN-ECCKN [19] proposes an SDN-based energy management system for WSN. The system reduces the total transmission time to increase the network lifetime. [20] minimizes energy comsumption on sensors with guaranteed quality-of-sensing in multi-task software defined WSN. It utilizes a centralized SDN to formulate the minimum-energy sensor activation by jointly considering sensor activation and task mapping. The work in [21] presents an energy-efficient routing algorithm based on the framework of software defined WSN. To minimize the transmission distance and the energy consumption of sensor nodes, the algorithm partitions WSN into clusters and dynamically assigns tasks to the intracluster nodes by a cluster control node. + +## VI. CONCLUSION + +We have presented a cluster-based SDN architecture Clu-Flow to manage communication flow in WSN, by controlling and monitoring the incoming and outgoing flow of cluster border nodes. CluFlow minimizes the number of border nodes and the communication overhead used for SDN control. Based on the simulations and the experiments in a real network, we have demonstrated that CluFlow significantly decreases the number of nodes and communication load needed by the SDN controller to control and monitor cluster-level communication flow compared with benchmark solutions. + +# REFERENCES + +[1] B. A. A. Nunes, M. Mendonca, X.-N. Nguyen, K. Obraczka, and T. Turletti, “A survey of software-defined networking: Past, present, and future of programmable networks,” IEEE Communications Surveys & Tutorials, vol. 16, no. 3, pp. 1617–1634, 2014. + +[2] I. T. Haque and N. Abu-Ghazaleh, “Wireless software defined networking: A survey and taxonomy,” IEEE Communications Surveys & Tutorials, vol. 18, no. 4, pp. 2713–2737, 2016. + +[3] H. Mostafaei and M. Menth, “Software-defined wireless sensor networks: A survey,” Journal of Network and Computer Applications, vol. 119, pp. 42–56, 2018. + +[4] N. McKeown, T. Anderson, H. Balakrishnan, G. Parulkar, L. Peterson, J. Rexford, S. Shenker, and J. Turner, “Openflow: enabling innovation in campus networks,” ACM SIGCOMM, vol. 38, no. 2, pp. 69–74, 2008. + +[5] F. Hu, Q. Hao, and K. Bao, “A survey on software-defined network and openflow: From concept to implementation,” IEEE Communications Surveys & Tutorials, vol. 16, no. 4, pp. 2181–2206, 2014. + +[6] T. Luo, H.-P. Tan, and T. Q. Quek, “Sensor openflow: Enabling software-defined wireless sensor networks,” IEEE Communications letters, vol. 16, no. 11, pp. 1896–1899, 2012. + +[7] R. Rahmani, H. Rahman, and T. Kanter, “On performance of logical-clustering of flow-sensors,” International Journal of Computer Science Issues, vol. 10, no. 5, pp. 1–13, 2013. + +[8] Y. Breitbart, C.-Y. Chan, M. Garofalakis, R. Rastogi, and A. Silberschatz, “Efficiently monitoring bandwidth and latency in ip networks,” in INFOCOM, vol. 2. IEEE, 2001, pp. 933–942. + +[9] M. R. Garey and D. S. Johnson, Computers and Intractability; A Guide to the Theory of NP-Completeness. Freeman & Co., 1990. + +New York, NY, USA: W. H. + +[10] P. Sanders, C. Schulz, D. Strash, and R. Williger, “Distributed evolutionary k-way node separators,” in Proceedings of the Genetic and Evolutionary Computation Conference. ACM, 2017, pp. 345–352. + +[11] Y. Boykov and V. Kolmogorov, “An experimental comparison of mincut/max-flow algorithms for energy minimization in vision,” IEEE transactions on pattern analysis and machine intelligence, vol. 26, no. 9, pp. 1124–1137, 2004. + +[12] G. Karakostas, “A better approximation ratio for the vertex cover problem,” in International Colloquium on Automata, Languages, and Programming. Springer, 2005, pp. 1043–1050. + +[13] F. Aurenhammer, “Voronoi diagramsa survey of a fundamental geometric data structure,” ACM Computing Surveys (CSUR), vol. 23, no. 3, pp. 345–405, 1991. + +[14] T. Winter, P. Thubert, A. Brandt, T. Clausen, J. Hui, R. Kelsey, P. Levis, K. Pister, R. Struik, and J. P. Vasseur, “Rpl: Ipv6 routing protocol for low power and lossy networks.” ROLL Working Group, 2011. + +[15] A. Detti, C. Pisa, S. Salsano, and N. Blefari-Melazzi, “Wireless mesh software defined networks (wmsdn),” in WiMob. IEEE, 2013, pp. 89– 95. + +[16] L. Galluccio, S. Milardo, G. Morabito, and S. Palazzo, “Sdn-wise: Design, prototyping and experimentation of a stateful sdn solution for wireless sensor networks,” in INFOCOM. IEEE, 2015, pp. 513–521. + +[17] A.-C. G. Anadiotis, L. Galluccio, S. Milardo, G. Morabito, and S. Palazzo, “Towards a software-defined network operating system for the iot,” in Internet of Things (WF-IoT), 2015 IEEE 2nd World Forum on. IEEE, 2015, pp. 579–584. + +[18] P. Berde, M. Gerola, J. Hart, Y. Higuchi, M. Kobayashi, T. Koide, B. Lantz, B. O’Connor, P. Radoslavov, W. Snow et al., “Onos: towards an open, distributed sdn os,” in Proceedings of the third workshop on Hot topics in software defined networking. ACM, 2014, pp. 1–6. + +[19] Y. Wang, H. Chen, X. Wu, and L. Shu, “An energy-efficient sdn based sleep scheduling algorithm for wsns,” Journal of Network and Computer Applications, vol. 59, pp. 39–45, 2016. + +[20] D. Zeng, P. Li, S. Guo, T. Miyazaki, J. Hu, and Y. Xiang, “Energy minimization in multi-task software-defined sensor networks,” IEEE transactions on computers, vol. 64, no. 11, pp. 3128–3139, 2015. + +[21] W. Xiang, N. Wang, and Y. Zhou, “An energy-efficient routing algorithm for software-defined wireless sensor networks,” IEEE Sensors Journal, vol. 16, no. 20, pp. 7393–7400, 2016. diff --git a/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..faf60bb2018bdb9c3da52effb79f3d7855d63cf5 --- /dev/null +++ b/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,63 @@ +and procedural standards applicable to the employees of the agency from which such employee is detailed and those of the Foundation. + +## (2) Voluntary service; acceptance of Federal employees + +## (A) Foundation + +The Executive Director of the Foundation may accept the services of employees detailed from Federal agencies with or without reimbursement to those agencies. + +## (B) Food and Drug Administration + +The Commissioner may accept the uncompensated services of Foundation fellows or trainees. Such services shall be considered to be undertaking an activity under contract with the Secretary as described in section 379 of this title. + +## (l) Annual reports + +## (1) Reports to Foundation + +Any recipient of a grant, contract, fellowship, memorandum of understanding, or cooperative agreement from the Foundation under this section shall submit to the Foundation a report on an annual basis for the duration of such grant, contract, fellowship, memorandum of understanding, or cooperative agreement, that describes the activities carried out under such grant, contract, fellowship, memorandum of understanding, or cooperative agreement. + +## (2) Report to Congress and the FDA + +Beginning with fiscal year 2009, the Executive Director shall submit to Congress and the Commissioner an annual report that— (A) describes the activities of the Foundation and the progress of the Foundation in furthering the goals and priorities established under subsection (c)(2), including the practical impact of the Foundation on regulated product development; + +(B) provides a specific accounting of the source and use of all funds used by the Foundation to carry out such activities; and + +(C) provides information on how the results of Foundation activities could be incorporated into the regulatory and product review activities of the Food and Drug Administration. + +## (m) Separation of funds + +The Executive Director shall ensure that the funds received from the Treasury are held in separate accounts from funds received from entities under subsection (i). + +## (n) Funding + +From amounts appropriated to the Food and Drug Administration for each fiscal year, the Commissioner shall transfer not less than \$500,000 and not more than \$1,250,000, to the Foundation to carry out subsections (a), (b), and + +(d) through (m). (June 25, 1938, ch. 675, § 770, as added Pub. L. 110–85, title VI, § 601(a), Sept. 27, 2007, 121 Stat. 890.) + +## § 379dd–1. Location of Foundation + +The Foundation shall, if practicable, be located not more than 20 miles from the District of Columbia. + +(June 25, 1938, ch. 675, § 771, as added Pub. L. 110–85, title VI, § 601(b), Sept. 27, 2007, 121 Stat. 897.) + +# § 379dd–2. Activities of the Food and Drug Administration + +## (a) In general + +The Commissioner shall receive and assess the report submitted to the Commissioner by the Executive Director of the Foundation under section 379dd(l)(2) of this title. + +## (b) Report to Congress + +Beginning with fiscal year 2009, the Commissioner shall submit to Congress an annual report summarizing the incorporation of the information provided by the Foundation in the report described under section 379dd(l)(2) of this title and by other recipients of grants, contracts, memoranda of understanding, or cooperative agreements into regulatory and product review activities of the Food and Drug Administration. + +## (c) Extramural grants + +The provisions of this part and section 360bbb–5 of this title shall have no effect on any grant, contract, memorandum of understanding, or cooperative agreement between the Food and Drug Administration and any other entity entered into before, on, or after September 27, 2007. (June 25, 1938, ch. 675, § 772, as added Pub. L. 110–85, title VI, § 601(b), Sept. 27, 2007, 121 Stat. 897.) + +## SUBCHAPTER VIII—IMPORTS AND EXPORTS + +# § 381. Imports and exports + +## (a) Imports; list of registered foreign establishments; samples from unregistered foreign establishments; examination and refusal of admission + +The Secretary of the Treasury shall deliver to the Secretary of Health and Human Services, upon his request, samples of food, drugs, devices, tobacco products, and cosmetics which are being imported or offered for import into the United States, giving notice thereof to the owner or consignee, who may appear before the Secretary of Health and Human Services and have the right to introduce testimony. The Secretary of Health and Human Services shall furnish to the Secretary of the Treasury a list of establishments registered pursuant to subsection (i) of section 360 or section 387e(h) of this title and shall request that if any drugs, devices, or tobacco products manufactured, prepared, propagated, compounded, or processed in an establishment not so registered are imported or offered for import into the United States, samples of such drugs, devices, or tobacco products be delivered to the Secretary of Health and Human Services, with notice of such delivery to the owner or consignee, who may appear before the Secretary of Health and Human Services and have the right to introduce testimony. If it appears from the examination of such samples or otherwise that (1) such article has been manufactured, processed, or packed under insanitary conditions or, in the case of a device, the meth- diff --git a/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..760d624f917012581622016256c53e454612df4e --- /dev/null +++ b/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +fiscal year limitation. Such fees shall be collected in each fiscal year in an amount equal to the amount specified in appropriations Acts for such fiscal year and shall only be collected and available for the costs of the Food and Drug Administration. (C) For purposes of this paragraph, a certification by the Secretary shall be made on such basis, and in such form (including a publicly available listing) as the Secretary determines appropriate. (D) With regard to fees pursuant to subparagraph (B) in connection with written export certifications for food: (i) Such fees shall be collected and available solely for the costs of the Food and Drug Administration associated with issuing such certifications. (ii) Such fees may not be retained in an amount that exceeds such costs for the respective fiscal year. + +## (f) Labeling of exported drugs + +(1) If a drug (other than insulin, an antibiotic drug, an animal drug, or a drug exported under section 382 of this title) being exported in accordance with subsection (e) of this section is being exported to a country that has different or additional labeling requirements or conditions for use and such country requires the drug to be labeled in accordance with those requirements or uses, such drug may be labeled in accordance with such requirements and conditions for use in the country to which such drug is being exported if it also is labeled in accordance with the requirements of this chapter. (2) If, pursuant to paragraph (1), the labeling of an exported drug includes conditions for use that have not been approved under this chapter, the labeling must state that such conditions for use have not been approved under this chapter. A drug exported under section 382 of this title is exempt from this section. + +## (g) Warning notice of importation in violation of chapter + +1. With respect to a prescription drug being imported or offered for import into the United States, the Secretary, in the case of an individual who is not in the business of such importations, may not send a warning notice to the individual unless the following conditions are met: (A) The notice specifies, as applicable to the importation of the drug, that the Secretary has made a determination that— (i) importation is in violation of subsection (a) of this section because the drug is or appears to be adulterated, misbranded, or in violation of section 355 of this title; (ii) importation is in violation of subsection (a) of this section because the drug is or appears to be forbidden or restricted in sale in the country in which it was produced or from which it was exported; (iii) importation is or appears to be in violation of subsection (d)(1) of this section; or (iv) importation otherwise is or appears to be in violation of Federal law. (B) The notice does not specify any provision described in subparagraph (A) that is not applicable to the importation of the drug. + +(C) The notice states the reasons underlying such determination by the Secretary, including a brief application to the principal facts involved of the provision of law described in subparagraph (A) that is the basis of the determination by the Secretary. + +(2) For purposes of this section, the term ‘‘warning notice’’, with respect to the importation of a drug, means a communication from the Secretary (written or otherwise) notifying a person, or clearly suggesting to the person, that importing the drug for personal use is, or appears to be, a violation of this chapter. + +## (h) Protection against adulteration of food + +1. The Secretary shall give high priority to increasing the number of inspections under this section for the purpose of enabling the Secretary to inspect food offered for import at ports of entry into the United States, with the greatest priority given to inspections to detect the intentional adulteration of food. (2) The Secretary shall give high priority to making necessary improvements to the information management systems of the Food and Drug Administration that contain information related to foods imported or offered for import into the United States for purposes of improving the ability of the Secretary to allocate resources, detect the intentional adulteration of food, and facilitate the importation of food that is in compliance with this chapter. (3) The Secretary shall improve linkages with other regulatory agencies of the Federal Government that share responsibility for food safety, and shall with respect to such safety improve linkages with the States and Indian tribes (as defined in section 450b(e) of title 25). + +## (i) Testing for rapid detection of adulteration of food + +1. For use in inspections of food under this section, the Secretary shall provide for research on the development of tests and sampling methodologies— (A) whose purpose is to test food in order to rapidly detect the adulteration of the food, with the greatest priority given to detect the intentional adulteration of food; and (B) whose results offer significant improvements over the available technology in terms of accuracy, timing, or costs. (2) In providing for research under paragraph (1), the Secretary shall give priority to conducting research on the development of tests that are suitable for inspections of food at ports of entry into the United States. (3) In providing for research under paragraph (1), the Secretary shall as appropriate coordinate with the Director of the Centers for Disease Control and Prevention, the Director of the National Institutes of Health, the Administrator of the Environmental Protection Agency, and the Secretary of Agriculture. (4) The Secretary shall annually submit to the Committee on Energy and Commerce of the House of Representatives, and the Committee on Health, Education, Labor, and Pensions of the Senate, a report describing the progress made in research under paragraph (1), including progress regarding paragraph (2). diff --git a/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c25f99e9e062dcb517bad8a3f10b4aafe8b7c588 --- /dev/null +++ b/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,39 @@ +as a similar article of food that is manufactured, processed, packed, or held in the United States in accordance with the requirements of this chapter; and (ii) the certification would assist the Secretary in determining whether to refuse or admit the article of food under subsection (a); and + +(D) information submitted to the Secretary in accordance with the process established in paragraph (7). + +## (3) Certifying entities + +For purposes of paragraph (1), entities that shall provide the certification or assurances described in such paragraph are— (A) an agency or a representative of the government of the country from which the article of food at issue originated, as designated by the Secretary; or (B) such other persons or entities accredited pursuant to section 384d of this title to provide such certification or assurance. + +## (4) Renewal and refusal of certifications + +The Secretary may— (A) require that any certification or other assurance provided by an entity specified in paragraph (2) be renewed by such entity at such times as the Secretary determines appropriate; and (B) refuse to accept any certification or assurance if the Secretary determines that such certification or assurance is not valid or reliable. + +## (5) Electronic submission + +The Secretary shall provide for the electronic submission of certifications under this subsection. + +## (6) False statements + +Any statement or representation made by an entity described in paragraph (2) to the Secretary shall be subject to section 1001 of title + +18. + +## (7) Assessment of food safety programs, systems, and standards + +If the Secretary determines that the food safety programs, systems, and standards in a foreign region, country, or territory are inadequate to ensure that an article of food is as safe as a similar article of food that is manufactured, processed, packed, or held in the United States in accordance with the requirements of this chapter, the Secretary shall, to the extent practicable, identify such inadequacies and establish a process by which the foreign region, country, or territory may inform the Secretary of improvements made to such food safety program, system, or standard and demonstrate that those controls are adequate to ensure that an article of food is as safe as a similar article of food that is manufactured, processed, packed, or held in the United States in accordance with the requirements of this chapter. (June 25, 1938, ch. 675, § 801, 52 Stat. 1058; Oct. 18, 1949, ch. 696, §§ 1–3, 63 Stat. 882; Pub. L. 87–781, title III, § 306, Oct. 10, 1962, 76 Stat. 796; Pub. L. 90–399, § 106, July 13, 1968, 82 Stat. 353; Pub. L. + +91–513, title II, § 701(h), Oct. 27, 1970, 84 Stat. 1282; Pub. L. 94–295, §§ 3(f), 4(b)(3), May 28, 1976, 90 Stat. 578, 580; Pub. L. 100–293, § 3, Apr. 22, 1988, 102 Stat. 96; Pub. L. 102–300, § 6(b)(1), June 16, 1992, 106 Stat. 240; Pub. L. 102–353, § 5, Aug. 26, 1992, 106 Stat. 943; Pub. L. 103–80, § 3(cc), (dd)(1), Aug. 13, 1993, 107 Stat. 778, 779; Pub. L. 104–134, title II, § 2102(a)–(c), Apr. 26, 1996, 110 Stat. 1321–313, 1321–314; Pub. L. 104–180, title VI, § 603(a), (b), Aug. 6, 1996, 110 Stat. 1594, 1595; Pub. L. 105–115, title I, § 125(a)(2)(D), Nov. 21, 1997, 111 Stat. 2325; Pub. L. 106–387, § 1(a) [title VII, §§ 745(c)(1), 746(c)], Oct. 28, 2000, 114 Stat. 1549, 1549A–36, 1549A–40; Pub. L. 107–188, title III, §§ 302(a)–(d), 303(c), 304(e), 305(c), 307(a), 308(a), 321(b)(1), 322(a), June 12, 2002, 116 Stat. 662, 663, 665, 667, 668, 670, 672, 676; Pub. L. 109–462, § 5(a), Dec. 22, 2006, 120 Stat. 3475; Pub. L. 110–85, title IX, § 912(b)(2), Sept. 27, 2007, 121 Stat. 952; Pub. L. 111–31, div. A, title I, § 103(l), June 22, 2009, 123 Stat. 1837; Pub. L. 111–353, title I, §§ 102(b)(3), 107(b), title II, § 204(j)(2), title III, §§ 301(c), 303(a)–(c), 304(a), Jan. 4, 2011, 124 Stat. 3889, 3910, 3937, 3955–3957.) + +## AMENDMENT OF SUBSECTION (a) + +Pub. L. 111–353, title III, § 301(c), (d), Jan. 4, 2011, 124 Stat. 3955, provided that, effective 2 years after Jan. 4, 2011, subsection (a) of this section is amended by inserting ‘‘or the importer (as defined in section 384a of this title) is in violation of such section 384a of this title’’ after ‘‘or in violation of section 355 of this title’’. + +## REFERENCES IN TEXT + +The Controlled Substances Import and Export Act, referred to in subsec. (a), is title III of Pub. L. 91–513, Oct. 27, 1970, 84 Stat. 1285, which is classified principally to subchapter II (§ 951 et seq.) of chapter 13 of this title. For complete classification of this Act to the Code, see Short Title note set out under section 951 of this title and Tables. The Federal Meat Inspection Act, referred to in subsec. (m)(3)(B), is titles I to IV of act Mar. 4, 1907, ch. 2907, as added Pub. L. 90–201, Dec. 15, 1967, 81 Stat. 584, which are classified generally to subchapters I to IV (§ 601 et seq.) of chapter 12 of this title. For complete classification of this Act to the Code, see Short Title note set out under section 601 of this title and Tables. The Poultry Products Inspection Act, referred to in subsec. (m)(3)(B), is Pub. L. 85–172, Aug. 28, 1957, 71 Stat. 441, which is classified generally to chapter 10 (§ 451 et seq.) of this title. For complete classification of this Act to the Code, see Short Title note set out under section 451 of this title and Tables. The Egg Products Inspection Act, referred to in subsec. (m)(3)(B), is Pub. L. 91–597, Dec. 29, 1970, 84 Stat. 1620, which is classified principally to chapter 15 (§ 1031 et seq.) of this title. For complete classification of this Act to the Code, see Short Title note set out under section 1031 of this title and Tables. + +## AMENDMENTS + +2011—Subsec. (a). Pub. L. 111–353, §§ 204(j)(2), 303(a), inserted ‘‘or (4) the recordkeeping requirements under section 2223 of this title (other than the requirements under subsection (f) of such section) have not been complied with regarding such article,’’ in the third sentence before ‘‘then such article shall be refused admission’’ and inserted after the third sentence ‘‘With respect to an article of food, if importation of such food is subject to, but not compliant with, the requirement under subsection (q) that such food be accompanied by a certification or other assurance that the food meets applicable requirements of this chapter, then such article shall be refused admission.’’ diff --git a/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6d4dd132e87afab9a866cc77ef5f9167d57c1c49 --- /dev/null +++ b/outputs/multi_column/01566a951fd40f8c1a4b8190cc3d0f93c393_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,45 @@ +‘‘Administrator’’ after ‘‘provisions of this subsection, the’’, ‘‘Secretary’s’’ for ‘‘Administrator’s’’ after ‘‘as may be specified in the’’, ‘‘Department of Health and Human Services’’ for ‘‘Federal Security Agency’’, and ‘‘Secretary’’ for ‘‘Administrator’’ after ‘‘designated by the’’. 1992—Subsecs. (a), (b). Pub. L. 102–300, which directed the substitution of ‘‘Health and Human Services’’ for ‘‘Health, Education, and Welfare’’ wherever appearing, was executed in second sentence of subsec. (a), but could not be executed in first sentence of subsec. (a) or in subsec. (b) because such words did not appear. See 1993 Amendment note above and Transfer of Functions note below. Subsec. (d)(1). Pub. L. 102–353 substituted ‘‘manufacturer of’’ for ‘‘person who manufactured’’. 1988—Subsecs. (d), (e). Pub. L. 100–293 added subsec. + +(d) and redesignated former subsec. (d) as (e). 1976—Subsec. (a). Pub. L. 94–295, §§ 3(f)(2), 4(b)(3), expanded provisions requiring the Secretary of Health, Education, and Welfare to request that the Secretary of the Treasury deliver to the Secretary of Health, Education, and Welfare items imported or offered for import into the United States that were manufactured, prepared, propagated, compounded, or processed in nonregistered establishments by extending the provisions to include devices imported or offered for import, and, in cl. (1), inserted reference to devices which were manufactured, packed, stored, or installed using methods, facilities, or controls not conforming to the requirements of section 360j(f) of this title. Subsec. (d). Pub. L. 94–295, § 3(f)(1), designated existing provisions as par. (1) and added par. (2). 1970—Subsec. (a). Pub. L. 91–513 substituted ‘‘Clause + +2. of the third sentence of this paragraph’’ for ‘‘This paragraph’’ and ‘‘the Controlled Substances Import and Export Act’’ for ‘‘section 173 of this title’’ in last sentence. 1968—Subsec. (d). Pub. L. 90–399 provided that nothing in subsec. (d) shall authorize the exportation of any new animal drug, or an animal feed bearing or containing a new animal drug, which is unsafe within the meaning of section 360b of this title. 1962—Subsec. (a). Pub. L. 87–781 inserted provisions requiring the Secretary of Health, Education, and Welfare to furnish the Secretary of the Treasury a list of establishments registered under section 360(i) of this title, and to request that samples of any drugs from any establishments not so registered be delivered to the Secretary of Health, Education, and Welfare, with notice of delivery to the consignee who may appear before the Secretary to testify. 1949—Subsec. (a). Act Oct. 18, 1949, § 1, inserted before period at end of second sentence ‘‘, except as provided in subsection (b) of this section. The Secretary of the Treasury shall cause the destruction of any such article refused admission unless such article is exported, under regulations prescribed by the Secretary of the Treasury within ninety days of the notice of such refusal or within such additional time as may be permitted pursuant to such regulations’’. Subsec. (b). Act Oct. 18, 1949, § 2, provided for express statutory authority for the long-standing administrative practice of releasing imported articles that do not comply with the requirements of the law so that they may be relabeled or given appropriate treatment to bring them into compliance. Subsec. (c). Act Oct. 18, 1949, § 3, charged all costs, including salaries and travel and subsistence expenses of officers and employees, against importers. + +## EFFECTIVE DATE OF 2011 AMENDMENT + +Amendment by section 301(c) of Pub. L. 111–353 effective 2 years after Jan. 4, 2011, see section 301(d) of Pub. L. 111–353, set out as a note under section 331 of this title. Pub. L. 111–353, title III, § 304(c), Jan. 4, 2011, 124 Stat. 3958, provided that: ‘‘The amendment made by this section [amending this section] shall take effect 180 days after the date of enactment of this Act [Jan. 4, 2011].’’ + +## EFFECTIVE DATE OF 2006 AMENDMENT + +Pub. L. 109–462, § 5(b), Dec. 22, 2006, 120 Stat. 3476, provided that: ‘‘The amendments made by this section [amending this section] shall take effect 1 year after the date of enactment of this Act [Dec. 22, 2006].’’ + +## EFFECTIVE DATE OF 2002 AMENDMENT + +Amendment by section 321(b)(1) of Pub. L. 107–188 effective upon the expiration of the 180-day period beginning June 12, 2002, see section 321(c) of Pub. L. 107–188, set out as a note under section 331 of this title. Amendment by section 322(a) of Pub. L. 107–188 effective upon the expiration of the 90-day period beginning June 12, 2002, see section 322(c) of Pub. L. 107–188, set out as a note under section 331 of this title. + +## EFFECTIVE DATE OF 1988 AMENDMENT + +Amendment by Pub. L. 100–293 effective upon expiration of 90 days after Apr. 22, 1988, see section 8(a) of Pub. L. 100–293, set out as a note under section 353 of this title. + +## EFFECTIVE DATE OF 1970 AMENDMENT + +Amendment by Pub. L. 91–513 effective on first day of seventh calendar month that begins after Oct. 26, 1970, see section 704 of Pub. L. 91–513, set out as an Effective Date note under section 801 of this title. + +## EFFECTIVE DATE OF 1968 AMENDMENT + +Amendment of subsec. (d) by Pub. L. 90–399 effective on first day of thirteenth calendar month after July 13, 1968, see section 108(a) of Pub. L. 90–399, set out as an Effective Date and Transitional Provisions note under section 360b of this title. + +## REGULATIONS + +Pub. L. 111–353, title III, § 304(b), Jan. 4, 2011, 124 Stat. 3958, provided that: ‘‘Not later than 120 days after the date of enactment of this Act [Jan. 4, 2011], the Secretary shall issue an interim final rule amending subpart I of part 1 of title 21, Code of Federal Regulations, to implement the amendment made by this section [amending this section].’’ Pub. L. 107–188, title III, § 307(c), June 12, 2002, 116 Stat. 672, provided that: + +‘‘(1) IN GENERAL.—Not later than 18 months after the date of the enactment of this Act [June 12, 2002], the Secretary of Health and Human Services shall promulgate proposed and final regulations for the requirement of providing notice in accordance with section 801(m) of the Federal Food, Drug, and Cosmetic Act [21 U.S.C. 381(m)] (as added by subsection (a) of this section). Such requirement of notification takes effect— + +‘‘(A) upon the effective date of such final regulations; or + +‘‘(B) upon the expiration of such 18-month period if the final regulations have not been made effective as of the expiration of such period, subject to compliance with the final regulations when the final regulations are made effective. + +‘‘(2) DEFAULT; MINIMUM PERIOD OF ADVANCE NOTICE.—If under paragraph (1) the requirement for providing notice in accordance with section 801(m) of the Federal Food, Drug, and Cosmetic Act [21 U.S.C. 381(m)] takes effect without final regulations having been made effective, then for purposes of such requirement, the specified period of time that the notice is required to be made in advance of the time of the importation of the article of food involved or the offering of the food for import shall be not fewer than eight hours and not more than five days, which shall remain in effect until the final regulations are made effective.’’ + +## SAVINGS PROVISION + +Amendment by Pub. L. 91–513 not to affect or abate any prosecutions for violation of law or any civil seizure or forfeitures and injunctive proceedings commenced prior to the effective date of such amendment, diff --git a/outputs/multi_column/019a8841dddeb304774ba62a9f5d8dccb43d_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/019a8841dddeb304774ba62a9f5d8dccb43d_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5474f0f30460866b010ae15abdebabdcc16cbb3a --- /dev/null +++ b/outputs/multi_column/019a8841dddeb304774ba62a9f5d8dccb43d_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +H. Jeulina, L. Prunab, JF. Lesesvec, A. Lozniewskia, P. Kaminskyd a Département de microbiologie, CHU Nancy Brabois, Vandœuvre lès Nancy, France + +b Médecine interne, hôpital de Brabois, Vandœuvre lès Nancy, France c Laboratoire d’hématologie biologique, CHU Nancy Brabois, Vandœuvre lès Nancy, France d Service de médecine interne, centre hospitalier universitaire, Nancy, France + +Introduction.– La dystrophie myotonique (DM1) est une maladie héréditaire autosomique dominante liée à une expansion anor-male de triplets CTG dans le gène DMPK. Elle est caractérisée par une myopathie, une myotonie, et une atteinte systémique endocrinienne, cardiaque, pneumologique et neurologique centrale. La classique hypogammaglobulinémie constatée dans cette affection est liée à un défaut d’affinité des IgG pour leur récepteur FcRn qui les protège de leur catabolisme. L’objet de ce travail était de vérifier si l’hypogammaglobulinémie est responsable d’un déficit immunitaire dans la DM1. Patients et méthodes.– L’étude a porté sur 22 hommes et 39 femmes DM1 âgés de 42,6 ± 12,9 ans. Les variables étudiées étaient la concentration sérique d’IgG, les sérologies pour les virus Herpes simplex (HSV), Varicelle zona (VZV), Epstein Barr (EBV), ainsi que les taux résiduels sériques post-vaccinaux pour les vaccins contre le virus de l’hépatite B (VHB), la poliomyélite et le tétanos. Résultats.– La concentration moyenne d’IgG était de 6,63 ± 2,35 g/l, 56,7 % et 26,7 % des patients ayant un taux d’IgG inférieur respectivement à la normale (n > 6,8 g/L) et à 5 g/L. Une séropositivité était observée chez 65,6 % des patients pour HSV, 93,2 % pour VZV et 93,3 % pour EBV, ce qui est comparable aux prévalences observées dans la population générale (respectivement 50,3 %, 98,8 % et 94 %). Les taux sériques d’IgG antiviraux étaient cependant corrélés au taux d’IgG totales (VZV : r = 0,28, p = 0, 04 ; HSV : r = 0,40, p = 0,01 ; EBV ECNA : r = 0,28, p = 0,04), mais il n’existait aucune différence entre les taux d’IgG sériques chez les patients séropositifs et séronégatifs. Vingt deux patients avaient été vaccinés contre le VHB et présentaient des taux résiduels comparables à ceux observés chez 372 patients VIH négatifs ayant consulté dans un CDAG (groupe contrôle). Enfin les taux résiduels d’IgG pour les vaccins obligatoires (poliomyélite et tétanos) étaient comparables à ceux observés dans la population générale. Conclusion.– Cette étude montre que malgré la fréquence élevée de l’hypogammaglobulinémie, il n’existe pas d’argument pour évoquer un déficit de l’immunité humorale chez les patients DM1. + +doi:10.1016/j.revmed.2011.03.293 + +## CA167 + +## Association non fortuite d’une neutropénie chronique et d’une maladie de Charcot-Marie-Tooth en rapport avec une mutation de la dynamine 2 + +A. Saint-Lézera, E. Ribeiroa, G. Soléb, P. Merciea, M. Longy-Boursier a + +a Médecine interne et maladies tropicales, hôpital Saint-André, CHU de Bordeaux, Bordeaux, France b Hôpital Haut-Lévêque, neurologie, CHU Bordeaux, Pessac, France + +Introduction.– La maladie de Charcot-Marie-Tooth (CMT) est une neuropathie héréditaire sensitivomotrice. Patients et méthodes.– Nous rapportons un cas de CMT en rapport avec une mutation de la dynamine 2 associée à une neutropénie chronique. Observation.– Un patient de 46 ans était adressé pour une neutropénie chronique modérée connue depuis 20 ans, et découverte sur un bilan systématique. On notait dans les antécédents une chirurgie des tendons d’Achille dans l’enfance. Il n’y avait jamais eu d’évènement infectieux notable. À l’examen, il existait aux membres inférieurs des pieds creux, des rétractions des tendons d’Achille, une amyotrophie des mollets, de la loge antéro-externe des jambes avec déficit moteur prédominant en flexion dorsale et steppage, une hypoesthésie avec hypopallesthésie distale ainsi qu’une aréflexie achilléenne. Aux membres supérieurs, on notait une amyotrophie du tiers distal des avant-bras sans déficit moteur. Le reste de l’examen était sans particularité. Biologiquement, il existait une neutropénie à 1240/mm3, isolée, avec leucocytes normaux à 5100/mm3, une élévation de la créatine kinase à 2,5 n. Le myélogramme montrait une dysgranulopoïèse. Les anticorps antigranulocytes étaient négatifs. L’électromyogramme était en faveur d’une forme intermédiaire de maladie de CMT. L’association d’une neutropénie et d’un tableau clinique et électrophysiologique de maladie de CMT justifiait l’étude moléculaire du gène codant pour la dynamine 2 qui retrouvait la mutation p.K562del. Discussion.– La maladie de CMT correspond à un groupe hétérogène de neuropathies héréditaires sensitivo-motrices. Le phénotype clinique classique [1] est caractérisé par un déficit moteur et une amyotrophie des muscles distaux prédominant sur la loge antéro-externe des jambes responsables d’un steppage, avec atteinte moins fréquente et plus tardive des mains. La diminution ou l’abolition des réflexes ostéo-tendineux touche les quatre membres, les réflexes achilléens étant principalement affectés. L’atteinte sensitive est surtout distale, pouvant affecter les différentes modalités sensitives. De manière fréquente s’associent des anomalies orthopédiques avec déformations des pieds et rachidiennes. La classification actuelle des différentes formes de CMT repose sur les données électrophysiologiques et sur le mode de transmission. L’étude électrophysiologique permet de distinguer les formes démyélinisantes, axonales et intermédiaires. Le mode de transmission peut être autosomique dominant, autosomique récessif ou lié à l’X. Le dernier niveau de classification est moléculaire. La dynamine 2 est une protéine ubiquitaire impliquées dans plusieurs fonctions cellulaires, notamment d’échange membranaire [2]. La dynamine 2 est responsable de deux entités pathologiques distinctes : la maladie de CMT [3] et la myopathie centro-nucléaire. Il s’agit d’une forme intermédiaire et de transmission autosomique dominante de CMT. Une neutropénie a été rapportée pour 2 familles porteuses de la maladie de CMT avec mutations p.K558del et p.K558E de la dynamine 2 ainsi que chez un patient porteur de la mutation p.K559del. Le mécanisme physiopathologique de cette neutropénie n’est pas élucidé. La présence d’une dynamine 2 normale pourrait être nécessaire à l’endocytose du récepteur du GCSF (granulocyte colony-stimulating factor) qui joue un rôle primordial dans la prolifération, la maturation et la survie des polynucléaires neutrophiles. Les neutropénies associées à une mutation de la dynamine 2 ne semblent pas entraîner d’infections plus fréquentes ou plus sévères. Conclusion.– La maladie de Charcot-Marie-Tooth correspond à un groupe hétérogène de neuropathies périphériques. Nous rapportons un cas original de neutropénie chronique associée à une maladie de Charcot-Marie-Tooth chez un patient porteur d’une mutation du gène codant pour la dynamine 2.Références Birouk N et al. Presse Med. 2009;38:200-9. Heymann JA et al. J Cell Sci. 2009;122:3427-31. Züchner S et al. Nat Genet. 2005;37:289-94. + +doi:10.1016/j.revmed.2011.03.294 + +## CA168 + +## Hypotension post prandiale sévérissime à propos d’un cas + +M. Arthuisa, P. Belenottia, M. Migerela, N. Enéa, C. Ferreiraa, L. Swiader a, J. Serratrice a, A. Benetos b, PJ. Weiller a + +a Médecine interne, CHU Timone, Marseille, France b Centre de gériatrie, CHU Nancy Brabois, Nancy, France + +Introduction.– Chutes et syncopes sont des accidents fréquents chez les personnes âgées, et sont dues à une grande variété de causes. L’hypotension post prandiale (HPP) survient particulièrement, chez diff --git a/outputs/multi_column/019a8841dddeb304774ba62a9f5d8dccb43d_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/019a8841dddeb304774ba62a9f5d8dccb43d_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..69dea2f4d43c6f77c22cafc03b56b529fc8269cc --- /dev/null +++ b/outputs/multi_column/019a8841dddeb304774ba62a9f5d8dccb43d_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,97 @@ +les patients porteurs de dysautonomie comme les parkinsoniens ou les patients institutionnalisés en Etablissement d’Hébergement pour Personnes Agées Dépendantes (EHPAD) où elle faite partie du bilan de chute [1]. Patients et méthodes.– Nous rapportons le cas d’une HPP survenue chez une patiente âgée de 82 ans, autonome et très active, chez qui la mise en place d’un traitement adapté a permis la reprise de ses activités. Cas Clinique.– Une patiente âgée de 82 ans, ayant pour habitude de jouer au golf à l’étranger, se plaint depuis un an environ de malaises avec liptohymie, survenant au décours de chacun des principaux repas et retentissant sur sa vie sociale. Elle est + +| | Cas 2 Homme 63 Droit ischémie | HNF | embolectomie | +| --- | --- | --- | --- | +| porteuse d’une hypertension modérée sous inhibiteurs calciques. | aiguë | + aspirine | Fogarty | + +Lorsque nous la voyons, les malaises pluriquotidiens ont été explorés en milieu endocrinologique spécialisé où la recherche d’une hypoglycémie post prandiale est restée complètement négative. L’examen clinique ne montre pas d’hypotension orthostatique. La tension artérielle passe de 190/90 mmHg à 90/60 mmHg en décubitus après le repas. Cette manœuvre est parfaitement reproductible et crée les malaises. Un traitement par Acarbose, hydratation et limitation glycémique permettra rapidement à la patiente de retrouver les greens. Discussion.– L’HPP est définie par une chute de plus de 20 mmHg de la pression artérielle systolique dans les deux heures suivant le repas [2]. L’ingestion d’un repas entraîne une séquestration sanguine dans le territoire splanchnique et une diminution des résistances vasculaires périphériques qui peuvent être à l’origine d’une diminution du retour veineux et donc du débit cardiaque. Les mécanismes tels que l’augmentation du rythme cardiaque, la vasoconstriction permettent de compenser la séquestration et de maintenir la pression artérielle chez le sujet sain. Une dérégulation des systèmes compensateurs est en général à l’origine des l’HPP. Le traitement repose sur le fractionnement des repas, l’arrêt de l’alcool, les inhibiteurs de l’alpha glucosidase, comme chez notre patiente. Conclusion.– Assez banale en EHPAD, l’hypotension post prandiale est rarement retrouvée à un tel degré chez une patiente ambulatoire. Elle peut être à l’origine de chutes parfois mortelles et justifie d’être connue et reconnue. D’autant qu’elle est sensible à un traitement simple est efficace. + +## Références + +[1] Puisieux F Presse Med 2003 [2] Gina L et al. Am J Med 2010 doi:10.1016/j.revmed.2011.03.295 + +## CA169 + +## Thrombose axillaire dans le cadre d’un syndrome de Pierre Marie et Sainton :à propos de deux cas familiaux et revue de la littérature + +C. Roncatoa, G. Denisb, S. Francoc, B. Duboquetd, F. Lorceriea, J. Magnant e, J.-L. Guilmot e + +a Service d’imagerie médicale, unité fonctionnelle d’angiologie, centre hospitalier, La Rochelle, France b Service de médecine interne, centre hospitalier, Rochefort, France c Service de chirurgie vasculaire et thoracique, centre hospitalier, La Rochelle, France d Service d’imagerie médicale, centre hospitalier, La Rochelle, France + +e Service de médecine interne et médecine vasculaire, centre hospitalier régional et universitaire, hôpital Bretonneau, Tours, France + +Introduction.– Le syndrome de Pierre Marie et Sainton (PMS) ou dysplasie cleïdo-crânienne (OMIM 119600) est une maladie orpheline caractérisée par un syndrome malformatif touchant le squelette axial avec notamment agénésie ou hypoplasie des clavicules. Une atteinte artérielle axillaire pourrait y être associée. + +Patients et méthodes.– Nous rapportons deux cas de thrombose de l’artère axillaire du coté dominant chez un frère et une sœur atteints. + +## Observation.– + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
SexeÂgeCôtéPrésentationTraitement
Clinique
Cas 1 Femme61Droitischémieclopidrogrelangioplastie
chronique+ aspirine, puis relais à 3 mois par+ stent
Cas 2 HommeAVK
63DroitischémieHNFembolectomie
aiguë+ aspirineFogarty
+ +Discussion.– Le PMS est une maladie autosomique dominante secondaire à une mutation du gène CBFA-1 porté par le chromosome 6p21 [1]. La prévalence est estimée à un pour 1 000,000 d’habitants dans le monde, 40 % sont des formes sporadiques. L’aspect clinique principal associe des agénésies ou hypoplasies des clavicules à des anomalies morphologiques crâniennes et maxillo-faciales diverses. L’atteinte des ceintures scapulaires se caractérise par une réduction de la distance bi acromiale et une hyper laxité ligamentaire. Trois autres cas de thromboses axillaires ont été rapportés dans la littérature [2,3]. Il s’agissait de trois femmes âgées entre 60 et 65 ans. Le diagnostic était clinique (Syndrome de Raynaud, douleur, claudication, ischémie digitale) et confirmé par une imagerie (écho Doppler, angio-TDM voire artériographie). La thrombose intéressait la partie proximale de l’artère axillaire du côté dominant et le mode de découverte était chronique dans les trois cas. Le mécanisme principal à l’origine de la thrombose serait une compression dynamique chronique et répétée par l’abaissement de la tête humérale ou du segment claviculaire résiduel lors des manœuvres d’adduction forcée. Ce phénomène peut être reproduit par des manœuvres lors de l’imagerie écho Doppler. En effet, dans nos deux cas le bilan de thrombophilie artérielle n’était pas contributif et il n’y avait pas d’argument pour une cause embolique ou pour une artérite inflammatoire. Dans un seul cas, une maladie athéromateuse infra clinique était associée. En cas de présentation chronique, l’angioplastie stenting n’a été essayée qu’une fois avec succès tandis que la chirurgie conventionnelle avec pontage s’est révélée difficile et peu efficace. Le maintien à long terme de ce résultat devra, néanmoins, être confirmé. Dans le seul cas révélé par une ischémie aiguë, l’embolectomie a été efficace initialement mais un tableau d’ischémie chronique pauci symptomatique a réapparu sur une rethrombose à six semaines. Conclusion.– Dans tous les cas, le traitement médical semble primordial associant contrôle des facteurs de risque cardio-vasculaire, antiagrégants plaquettaires, statines et kinésithérapie. La prise en charge préventive des ascendants n’est pas codifiée. + +## Références + +[1] Mundlos S et al. J Med Genet 1999;36:177–82. [2] Qureshi KN et al. J Vasc Surg 1997;26:888–90. + +[3] Campos JW et al. Sao Paulo Med J 2005:123:292–4. + +doi:10.1016/j.revmed.2011.03.296 + +## CA170 + +## Ulcères chroniques des membres inférieurs sans maladie artérielle, veineuse ou lymphatique : penser au « Deck chair leg syndrome » + +A. Lopesa, O Ben. Abdallaha, V. Delceyb, A. Petitc, M. Halabi-Tawil c, P. Sellier d, JF. Bergmann d + +a Médecine interne A, hôpital Lariboisière, Paris, France b Service de médecine interne A, hôpital Lariboisière, Paris, France diff --git a/outputs/multi_column/01c9b1f7647262a22ec85b5851d033f84650_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/01c9b1f7647262a22ec85b5851d033f84650_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..79a299e7f2bcd09be25adf2947c49b5661516e25 --- /dev/null +++ b/outputs/multi_column/01c9b1f7647262a22ec85b5851d033f84650_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,79 @@ +16. Lutz AM, Hampe R, Roos M, Lumkemann N, Eichberger + +M, et al. (2019) Fracture resistance and 2-body wear of 3-dimensional-printed occlusal devices. J Prosthet Dent 121: 166-172. + +17. Perea-Lowery L, Gibreel M, Vallittu PK, Lassila L (2020) + +Characterization of the mechanical properties of CAD/CAM polymers for interim fixed restorations. Dent Mater J 39: 319-325. + +18. Balkenhol M, Mautner MC, Ferger P, Wostmann B (2008) + +Mechanical properties of provisional crown and bridge materials: Chemical-curing versus dual-curing systems. J Dent 36: 15-20. + +19. Nejatidanesh F, Momeni G, Savabi O (2009) Flexural + +strength of interim resin materials for fixed prosthodontics. J Prosthodont 18: 507-511. + +20. Schwantz JK, Oliveira-Ogliari A, Meereis CT, Leal FB, Ogliari FA, et al. (2017) Characterization of bis-acryl composite resins for provisional restorations. Braz Dent J 28: 354-361. + +21. Bergamo ETP, Campos TMB, Piza MMT, Gutierrez E, Lopes ACO, et al. (2022) Temporary materials used in prosthodontics: The effect of composition, fabrication mode, and aging on mechanical properties. J Mech Behav Biomed Mater 133: 105333. + +22. Kadiyala KK, Badisa MK, Anne G, Anche SC, Chiramana S, et al. (2016) Evaluation of flexural strength of thermocycled interim resin materials used in prosthetic rehabilitation- an in-vitro study. J Clin Diagn Res 10: 91-95. + +23. Ellakany P, Fouda SM, Mahrous AA, AlGhamdi MA, Aly + +NM (2022) Influence of CAD/CAM milling and 3D-printing fabrication methods on the mechanical properties of 3-unit interim fixed dental prosthesis after thermo-mechanical aging process. Polymers (Basel) 14: 4103. + +24. Al-Qahtani AS, Tulbah HI, Binhasan M, Abbasi MS, Ahmed + +N, et al. (2021) Surface properties of polymer resins fabricated with subtractive and additive manufacturing techniques. Polymers 13: 4077. + +25. Tahayeri A, Morgan M, Fugolin AP, Bompolaki D, Athirasala + +A, et al. (2018) 3D printed versus conventionally cured provisional crown and bridge dental materials. Dent Mater 34: 192-200. + +26. Tapie L, Lebon N, Mawussi B, Fron-Chabouis H, Duret F, et + +al. (2015) Understanding dental CAD/CAM for restorations--accuracy from a mechanical engineering viewpoint. Int J Comput Dent 18: 343-367. + +27. Alharbi N, Osman R, Wismeijer D (2016) Effects of build + +direction on the mechanical properties of 3D-printed complete coverage interim dental restorations. J Prosthet Dent 115: 760-767. + +28. Osman RB, Alharbi N, Wismeijer D (2017) Build angle: Does + +it influence the accuracy of 3d-printed dental restorations using digital light-processing technology? Int J Prosthodont 30: 182-188. + +29. Cascón WP, Nuñez AP, Díez IC, Revilla-Leon M + +(2019) Laboratory workflow to obtain long-term injected resin composite interim restorations from an additive manufactured esthetic diagnostic template. J Esthet Restor Dent 31: 13-19. + +30. Derban P, Negrea R, Rominu M, Marsavina L (2021) + +Influence of the printing angle and load direction on flexure strength in 3d printed materials for provisional dental restorations. Materials (Basel) 14: 3376. + +31. Reymus M, Fabritius R, Keßler A, Hickel R, Edelhoff D, et al. (2020) Fracture load of 3D-printed fixed dental prostheses compared with milled and conventionally fabricated ones: The impact of resin material, build direction, post-curing, and artificial aging-an in vitro study. Clin Oral Investig 24: 701-710. + +32. Väyrynen VOE, Tanner J, Vallittu PK (2016) The + +anisotropicity of the flexural properties of an occlusal device material processed by stereolithography. J Prosthet Dent 116: 811-817. + +33. Unkovskiy A, Bui PH, Schille C, Geis-Gerstorfer J, Huettig + +F, et al. (2018) Objects build orientation, positioning, and curing influence dimensional accuracy and flexural properties of stereolithographically printed resin. Dent Mater 34: 324-333. + +34. Stawarczyk B, Ender A, Trottmann A, Özcan M, Fischer + +J, et al. (2012) Load-bearing capacity of CAD/CAM milled polymeric three-unit fixed dental prostheses: effect of aging regimens. Clin Oral Investig 16: 1669-1677. + +35. Turksayar AAD, Donmez MB, Olcay EO, Demirel M, Demir E (2022) Effect of printing orientation on the fracture strength of additively manufactured 3-unit interim fixed dental prostheses after aging. J Dent 124: 104155. + +36. Diaz-Arnold AM, Dunne JT, Jones AH (1999) Microhardness + +of provisional fixed prosthodontic materials. J Prosthet Dent 82: 525-528. + +37. KeblerA, Hickel R, Ilie N (2021) In vitro investigation of + +the influence of printing direction on the flexural strength, flexural modulus and fractographic analysis of 3D-printed temporary materials. Dent Mater J 40: 641-649. + +![](figure) diff --git a/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_12_pg1_pg1_repeat1.md b/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_12_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c92fea1ca04621334774adb7e49d53a22a0e144e --- /dev/null +++ b/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_12_pg1_pg1_repeat1.md @@ -0,0 +1,37 @@ +a list of several cell-impermeant nucleic acid stains and Section 8.1 for a general discussion of dye binding to nucleic acids. + +## SYTOX® Nucleic Acid Stains + +Many polar nucleic acid stains will enter eukaryotic cells with damaged plasma membranes yet will not stain dead bacteria with damaged plasma membranes. SYTOX® Green nucleic acid stain (S7020) is a high-affinity probe that easily penetrates eukaryotic cells and both gram-positive and gram-negative bacteria with compromised plasma membranes, yet is completely excluded from live cells.61 After brief incubation with the SYTOX® Green nucleic acid stain, dead bacteria fluoresce bright green when excited with the 488 nm spectral line of the argon-ion laser or any other 470–490 nm source (Figure 15.2.20). These properties, combined with its ~1000-fold fluorescence enhancement upon nucleic acid binding, make our SYTOX® Green stain a simple and quantitative dead-cell indicator for use with fluorescence microscopes, fluorometers, fluorescence microplate readers or flow cytometers + +![](figure) + +Figure 15.2.20 Absorption and fluorescence emission spectra of the SYTOX® Green nucleic acid stain bound to DNA. + +![](figure) + +![](figure) + +![](figure) + +Figure 15.2.22 Bovine pulmonary artery endothelial cells (BPAEC) incubated with the fixable, mitochondrion-selective MitoTracker® Red CMXRos (M7512). After staining, the cells were formaldehyde-fixed, acetone-permeabilized, treated with DNase-free RNase and counterstained using SYTOX® Green nucleic acid stain (S7020). Microtubules were labeled with a mouse monoclonal anti–ß-tubulin antibody, biotin-XX goat anti–mouse IgG antibody (B2763) and Cascade Blue® NeutrAvidin™ biotin-binding protein (A2663). This photograph was taken using multiple exposures through bandpass optical filters appropriate for Texas Red® dye, fluorescein and DAPI using a Nikon® Labophot 2 microscope equipped with a Quadfluor epi-illumination system. + +![](figure) + +Figure 15.2.23 A frozen section of zebrafish retina stained with mouse monoclonal antibody FRet 43 in conjunction with Texas Red®-X goat anti–mouse IgG (T6390), Alexa Fluor® 350 wheat germ agglutinin (W11263) and SYTOX® Green nucleic acid stain (S7020). + +(Figure 15.2.21). We have taken advantage of the sensitivity of the SYTOX® Green nucleic acid stain in our ViaGram™ Red+ Bacterial Gram Stain and Viability Kit (V7023) and in our Single Channel Annexin V/ Dead Cell Apoptosis Kit (V13240, Section 15.5). An important application of the SYTOX® Green nucleic acid stain is the high-throughput screening of bacteria for antibiotic susceptibility by fluorescence microscopy, by flow cytometry or in a fluorescence microplate reader.62 The SYTOX® Green nucleic acid stain as a tool for viability assessment is not restricted to bacteria; it is also a very effective cell-imper-meant counterstain in eukaryotic systems (Section 12.5). It can be used in conjunction with blue- and red-fluorescent labels for multiparameter analyses in fixed cells and tissue sections (Figure 15.2.22, Figure 15.2.23, Figure 15.2.24). Furthermore, it should be possible to combine the SYTOX® Green nucleic acid stain with one of the membrane-per-meant nucleic acid stains in our SYTO® Red-, SYTO® Blue- or SYTO® Orange-Fluorescent Nucleic Acid Stain Sampler Kits (S11340, S11350, S11360) for two-color visualization of dead and live cells. + +![](figure) + +![](figure) + +Figure 15.2.21 Quantitative flow cytometric analysis of Escherichia coli viability using the SYTOX® Green nucleic acid stain (S7020). A bacterial suspension containing an equal number of live and isopropyl alcohol–killed E. coli was stained with SYTOX® Green and analyzed using excitation at 488 nm. A bivariate frequency distribution for forward light scatter versus log fluorescence intensity (collected with a 510 nm longpass optical filter) shows two clearly distinct populations. When live and dead bacteria were mixed in varying proportions, a linear relationship between the population numbers and the actual percentage of live cells in the sample was obtained (see inset). + +![](figure) + +![](figure) + +![](figure) + +Figure 15.2.24 The mitochondria of bovine pulmonary artery endothelial cells stained with MitoTracker® Red CM-H2XRos (M7513). The cells were subsequently fixed, permeabilized and treated with RNase. Then the nuclei were stained with SYTOX® Green nucleic acid stain (S7020). The multiple-exposure photomicrograph was acquired using a fluorescence microscope equipped with bandpass filter sets appropriate for fluorescein and Texas Red® dyes. diff --git a/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_49_pg1_pg1_repeat1.md b/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_49_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..46cb0eac6195431f9fff290094aa5f51992f3183 --- /dev/null +++ b/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_49_pg1_pg1_repeat1.md @@ -0,0 +1,65 @@ +The CyQUANT® cell proliferation assay has a number of significant advantages over other proliferation assays: + +- Sensitivity and linearity. The CyQUANT® assay is linear from 50 or fewer cells to at least 50,000 cells in 200 µL volumes (Figure 15.4.12); increasing the dye concentration extends the linear range to at least 250,000 cells. Methods that employ Hoechst 33258 66 (H1398, H3569, H21491) or Hoechst 33342 67 (H1399, H3570, H21492) to measure cell number and proliferation are much less sensitive—detection limits of 500 cells for Hoechst 33258 66 or 2500 cells for Hoechst 33342 67—and have much smaller effective ranges. + +- No radioactivity. Unlike assays that measure 3H-thymidine incorporation, the CyQUANT® assay does not require radioisotopes and thus does not have the hazards or the expense associated with use, storage and disposal of radioisotopes. + +- Quick and easy protocol. The CyQUANT® assay is a single-step procedure that requires no lengthy incubation steps and can be completed within an hour (Figure 15.4.11). + +- Specificity and reliability. The assay is specific for total nucleic acids, with essentially no interference from other cell components. No wash steps are required because cellular growth media do not significantly interfere with CyQUANT® GR fluorescence. The CyQUANT® assay is reliable for cell quantitation, even without treatment to eliminate cellular RNA. However, addition of RNase or DNase permits the easy quantitation of DNA or RNA, respectively, in the sample. + +- Convenience. Unlike assays that use tetrazolium salts,3H-thymi-dine, BrdU, neutral red or methylene blue,67–70 the CyQUANT® procedure is not dependent on cellular metabolism. Thus, cells can be frozen and stored prior to assaying, with no reduction in signal, or they can be assayed immediately after collection. Time-course assays are simplified because data obtained from stored samples taken at widely different time intervals can be assayed together with a single standard curve determination. + +We have found the CyQUANT® Cell Proliferation Assay Kit to be useful for assaying widely disparate cell types, including: + +- Human neonatal fibroblasts, keratinocytes, melanocytes, umbilical vein endothelial cells (HUVEC) and dermal microvascular endothelial cells (DMVEC) + +Ex = 485 nm + +0 + +0 250 500 750 1000 Number of cells + +10000 20000 30000 40000 50000 Cells/well + +![](figure) + +Figure 15.4.12 Quantitation of NIH 3T3 fibroblasts using the CyQUANT® Cell Proliferation Assay Kit (C7026). Fluorescence measurements were made using a microplate reader with excitation at 485 nm and emission detection at 530 nm. The linear range of the assay under these conditions is from 50 to 50,000 cells per 200 µL sample. The inset shows the linearity that can be obtained at very low numbers of cells. + +- Murine fibroblasts (NIH 3T3 and CRE BAG 2 cells) and myeloma (P3X63A68) cells + +- Madin–Darby canine kidney (MDCK) cells + +- Chinook salmon embryo (CHSE) cells + +- Rat basophilic leukemia (RBL) and glioma (C6) cells + +Determination of total cell number using the CyQUANT® GR reagent is potentially useful for quantitating cell adhesion (see “Cell Adhesion” in Section 15.6) and for determining the total number of cells in a tissue. Each CyQUANT® Cell Proliferation Assay Kit (C7026) includes: + +- CyQUANT® GR reagent + +- Cell-lysis buffer + +- DNA standard for calibration + +- Detailed protocols + +The kit supplies sufficient materials for performing 1000 assays based on a 200 µL sample volume or a proportionately lower number of assays with a larger sample volume. The CyQUANT® cell-lysis buffer (a 20X concentrate, C7027) is also available separately and has been formulated to produce efficient lysis, to protect nucleic acids from nuclease activity and to dissociate proteins that may interfere with dye binding to nucleic acids. It may prove generally useful in the development of other assays that require cell lysis. + +## CyQUANT® NF Cell Proliferation Assay Kit + +The CyQUANT® NF Cell Proliferation Assay Kit provides a fast and sensitive method for counting cells in a population and measuring proliferation in microplate format. 71 This assay can be completed in 1 hour, with no washes, cell lysis, long incubations or radioactivity required, and it is not dependent on physiological activities that may exhibit cell number–independent variability. The CyQUANT® NF assay eliminates the freeze-thaw cell lysis step of the original CyQUANT® cell proliferation assay by using a cell-permeant DNA-binding dye in combination with a plasma membrane–permeabilization reagent. The CyQUANT® NF assay protocol requires only aspiration of growth medium (for adherent cells), replacement with dye binding solution, incubation for 30–60 minutes and then measurement of fluorescence in a microplate reader. The CyQUANT® NF assay has a linear detection range from at least 100 to 20,000 cells per well in most cell lines using a 96-well microplate format and a 100 µL assay volume. The CyQUANT® NF Cell Proliferation Assay Kit can be used with either a 96-well or 384-well microplate format and is available in two configurations: a 200-assay kit (C35007) and a 1000-assay kit (C35006) for high-throughput applications. Each kit contains: + +- CyQUANT® NF dye reagent + +- Dye delivery reagent + +- Concentrated Hank’s balanced salt solution (HBSS) + +- Detailed protocols + +# CyQUANT® Direct Cell Proliferation Assay Kit + +CyQUANT® Direct Cell Proliferation Assay is a fluorescence-based proliferation and cytotoxicity assay for microplate readers. The no-wash, homogeneous format and fast add-mix-read protocol makes the CyQUANT® Direct assay ideal for high-throughput screening (HTS) applications. The assay can be completed in 1 hour, with no washes, cell + +![](figure) diff --git a/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_66_pg1_pg1_repeat1.md b/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_66_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..44c230fcd15863ccb1cf183d2b52fa73373d8942 --- /dev/null +++ b/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_66_pg1_pg1_repeat1.md @@ -0,0 +1,77 @@ +The APO-BrdU™ TUNEL Assay Kit includes complete protocols for use in flow cytometry applications, though it may also be adapted for use with fluorescence microscopy. Each kit contains: + +- Terminal deoxynucleotidyl transferase (TdT), for catalyzing the addition of BrdUTP at the break sites + +- 5-Bromo-2ʹ-deoxyuridine 5ʹ-triphosphate (BrdUTP) + +- Alexa Fluor® 488 dye–labeled anti-BrdU mouse monoclonal antibody PRB-1, for detecting BrdU labels + +- Propidium iodide/RNase staining buffer, for quantitating total cellular DNA + +- Reaction, wash and rinse buffers + +- Positive control cells (a fixed human lymphoma cell line) + +- Negative control cells (a fixed human lymphoma cell line) + +- Detailed protocols + +Sufficient reagents are provided for approximately 60 assays of 1 mL samples, each containing approximately 1 x 106 cells/mL. + +## Detecting DNA Strand Breaks with ChromaTide® Nucleotides + +Break sites have traditionally been labeled with biotinylated dUTP, followed by subsequent detection with an avidin or streptavidin conjugate 37–40 (Section 7.6, Table 7.9). However, a more direct approach for detecting DNA strand breaks in apoptotic cells is possible via the use of our ChromaTide® BODIPY® FL-14-dUTP (C7614) as a TdT substrate 41,42 (Figure 15.5.9). The single-step BODIPY® FL dye–based assay has several advantages over indirect detection of biotinylated or haptenylated nucleotides, including fewer protocol steps and increased cell yields. BODIPY® FL dye–labeled nucleotides have also proven superior to fluorescein-labeled nucleotides for detection of DNA strand breaks in apoptotic cells because they provide stronger signals, a narrower emission spectrum and less photobleaching 41 (Figure 15.5.9). In situ DNA modifications by labeled nucleotides have been used to detect DNA fragmentation in what may be apoptotic cells in autopsy brains of Huntingtons and Alzheimer disease patients.43–46 DNA fragmentation is also associated with amyotrophic lateral sclerosis.47 + +Analogous to TdT’s ability to label double-strand breaks, the E. coli repair enzyme DNA polymerase I can be used to detect single-strand nicks,48,49 which appear as a relatively early step in some apoptotic processes.50–52 Because our ChromaTide® BODIPY® FL-14-dUTP (C7614) and ChromaTide® fluorescein-12-dUTP 53,54 (C7604) are incorporated into DNA by E. coli DNA polymerase I, they are also effective for in situ labeling with the nick translation method.55 + +## High-Content Analysis of Genotoxicity and Cytotoxicity + +In mammalian cells, a double-strand break (DSB) in genomic DNA is a potentially lethal lesion. One of the earliest known responses to DSB formation is phosphorylation of H2A histones. Specifically, DNA damaging agents induce phosphorylation of histone variant H2AX at Ser139, leading to the formation of DNA foci at the site of DNA DSBs.56–58 The HCS DNA Damage Kit (H10292) was developed to enable simultaneous quantitation of two cell health parameters, genotoxicity and cytotoxicity, by high-content analysis in the same cell (Figure 15.5.10). DNA damage is measured as an indication of genotoxicity and accomplished by specific antibody-based detection of phosphorylated H2AX (Ser139) in the nucleus. Cytotoxicity is measured with the Image-iT® DEAD Green™ viability stain (also available as a stand-alone reagent, I10291), + +![](figure) + +![](figure) + +Figure 15.5.9 HL-60 cells treated with camptothecin for 3 hours. The DNA strand nicks characteristic of apoptosis were detected with the TUNEL (terminal deoxynucleotidyl transferase–mediated dUTP nick end-labeling) assay using the fluorescently labeled nucleotide ChromaTide® BODIPY® FL-14-dUTP (C7614). Image contributed by Zbigniew Darzynkiewicz, Cancer Research Institute, New York Medical College. + +300 + +![](figure) + +![](figure) + +![](figure) + +● pH2AX nuclear intensity ● Image-iT® DEAD Green™ viability stain ● Cell number + +250 + +200 + +150 + +100 + +50 + +Untreated + +0 + +0 + +30 + +120 + +Valinomycin (µM) + +120 µM Valinomycin + +![](figure) + +![](figure) + +Figure 15.5.10 Detection of genotoxicity and cytotoxicity in valinomycin-treated A549 cells using the HCS DNA Damage Kit (H10292). A549 cells were treated with 30 µM or 120 µM valinomycin for 24 hr before performing the assay. With increasing concentrations of valinomycin, cells showed genotoxic effects as indicated by detection with a pH2AX antibody in conjunction with Alexa Fluor® 555 goat anti–mouse IgG antibody (orange fluorescence), and cytotoxic effects as indicated by staining with the Image-iT® DEAD Green™ viability stain (green fluorescence). Blue-fluorescent Hoechst 33342 was used as a nuclear segmentation tool, and Alexa Fluor® 647 phalloidin was used to visualize F-actin (pseudocolored magenta). The image on the left shows untreated cells with intact F-actin cytoskeletons and no evidence of cytotoxicity or genotoxicity. The image on the right shows cells treated with 120 µM valinomycin, which completely disrupted the actin cytoskeletons, increased levels of DNA damage and compromised plasma membrane integrity. + +![](figure) diff --git a/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_67_pg1_pg1_repeat1.md b/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_67_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f4776f46dbe6b7cab56551c88557cf206c4ab1a3 --- /dev/null +++ b/outputs/multi_column/01ed6dcc6a3d0237daa88b293d0c0667df1a_page_67_pg1_pg1_repeat1.md @@ -0,0 +1,161 @@ +a cell-impermeant, non⁄ uorescent, high-affinity DNA stain that forms highly ⁄ uorescent and stable dye–nucleic acid complexes when bound to DNA. Thus, staining of nuclear DNA by the Image-iT® DEAD Green™ viability stain cannot occur in live cells due to the impermeability of the plasma membrane to the stain. Drugs and test compounds that lead to serious cell injuries, including plasma membrane permeability, allow entry of the Image-iT® DEAD Green™ viability stain, enabling discrimination of dead cells. Hoechst 33342, which stains nuclear DNA in live and dead cells, is included in the kit as a segmentation tool for automated image analysis. The HCS DNA Damage Kit contains sufficient material to perform the DNA damage assay on two 96-well plates when used as described in the protocol provided: + +- Image-iT® Dead Green viability stain + +- pH2AX mouse monoclonal antibody + +- Alexa Fluor® 555 goat anti–mouse IgG antibody + +- Hoechst 33342 nucleic acid stain + +- Detailed protocols + +Because no single parameter fully defines cell viability in all systems, it is often useful to use multiple approaches to study cytotoxicity. In addition to the HCS DNA Damage Kit, we offer the HCS LIVE⁄DEAD® Green Kit (H10290) and the HCS Mitochondrial Health Kit (H10295), both of which employ the Image-iT® DEAD™ Green viability stain. Additionally, the HCS LIVE/DEAD® Kit provides a choice of two nucleic acid stains—the far-red–⁄ uorescent HCS NuclearMask™ Deep Red stain (H10294, Section 12.5) and the blue-⁄ uorescent Hoechst 33342 (H1399, H3570, H21492; Section 12.5)—for use as cell-permeant nuclear segmentation tools. The HCS Mitochondrial Health Kit provides Image-iT® DEAD Green viability stain and Hoechst 33342 stain, + +HO + +O + +O + +(CH3CH2)2N + +(CH2)3�O3 CH2 N CH3 (CH2)��CH3 + +![](figure) + +Figure 15.5.11 F2N12S, a component of the Violet Ratiometric Membrane Asymmetry Probe/Dead Cell Apoptosis Kit (A35137). + +262,144 + +196,608 + +131,072 + +A + +A+D + +65,536 + +L + +0 + +![](figure) + +65,536 131,072 196,608 262,144 + +0 + +F2N12S orange fluorescence + +![](figure) + +262,144 + +196,608 + +131,072 + +B + +A+D + +65,536 + +L + +0 + +![](figure) + +0 + +F2N12S orange fluorescence + +![](figure) + +65,536 131,072 196,608 262,144 as well as the MitoHealth stain, which accumulates in the mitochondria of live cells in proportion to the mitochondrial membrane potential. Both of these kits provide sufficient reagents to perform the assays on two 96-well plates, using the protocol provided. + +# Apoptosis Assays that Detect Membrane Asymmetry + +## Violet Ratiometric Membrane Asymmetry Probe/Dead Cell Apoptosis Kit + +The Violet Ratiometric Membrane Asymmetry Probe/Dead Cell Apoptosis Kit (A35137) provides a simple and fast method for detecting apoptosis with dead-cell discrimination by ⁄ ow cytometry. The violet ratiometric membrane asymmetry probe, F2N12S (4ʹ-N,N-diethylamino-6-(N-dodecyl-N-methyl-N-(3-sulfopropyl))ammonio-methyl-3-hydroxy⁄ avone, Figure 15.5.11), is a novel violet diode–excitable dye for the detection of membrane phospholipid asymmetry changes during apoptosis. This dye exhibits an excited-state intramolecular proton transfer (ESIPT) reaction, resulting in a dual ⁄ uorescence with two emission bands corresponding to 530 nm and 585 nm and producing a two-color ratiometric response to variations in surface charge.59 This ratiometric probe is therefore a self-calibrating indicator of apoptotic transformation, which is independent of probe concentration, cell size and instrument variation, such as ⁄ uctuations of laser intensity or sensitivity of the detectors. Given that apoptosis modifies the surface charge of the outer lea⁄ et of the plasma membrane, F2N12S can be used to monitor changes in membrane asymmetry that occur during apoptosis through a change in the relative intensity of the two emission bands of the dye 59 (Figure 15.5.12). The F2N12S-based apoptosis assay allows samples to be analyzed after a 5-minute incubation at room temperature and does not require special buffers or wash steps. This kit can be paired with other reagents such as MitoProbe™ DiIC1(5) or annexin V for multiparametric analysis of apoptosis and viability. The kit components, number of assays and assay principles are summarized in Table 15.4. + +## Annexin V Conjugates + +The human vascular anticoagulant annexin V is a 35–36 kilodalton, Ca2+-dependent phospholipid-binding protein that has a high affinity for the anionic phospholipid phosphatidylserine (PS). In normal + +105 + +104 + +C + +D + +103 + +L + +A + +102 + +101 + +![](figure) + +0 + +1,250 + +2,500 + +3,750 + +5,000 + +F2N12S ratio 585 nm/530 nm fluorescence x 1,000 + +![](figure) + +105 + +104 + +D + +D + +103 + +L + +A + +102 + +101 + +![](figure) + +0 + +1,250 + +2,500 + +3,750 + +5,000 + +F2N12S ratio 585 nm/530 nm fluorescence x 1,000 + +![](figure) + +Figure 15.5.12 Jurkat cells (T-cell leukemia, human) treated with 10 μM camptothecin for 4 hours (B and D) or untreated (A and C), control. Cells were stained according to the protocol. Samples were analyzed on a flow cytometer with 405 nm excitation using 585 nm and 530 nm bandpass filters for F2N12S and 488 nm excitation for SYTOX® AADvanced™ dead cell stain using a 695 nm bandpass filter. In panels A and B, live cells can be discriminated from apoptotic and dead cells by the relative intensities of the two emission bands from F2N12S. In C and D, SYTOX® AADvanced™ dead cell stain fluorescence is plotted against a derived ratio parameter from the two emission bands (585/530 nm) of F2N12S. A = apoptotic cells, L = live cells, D = dead cells. + +![](figure) diff --git a/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b2365179dee403adbac5c7b52037395462a1d54f --- /dev/null +++ b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +REVEGETATION OF NON-TOPSOILED, ORPHAN BENTONITE MINE SPOIL IN WYOMING AS INFLUENCED BY ORGANIC AND INORGANIC AMENDMENTS 1 + +by + +Kellie S. Moore, Edward J. DePuit, Gerald E. Schuman, James L. Meining, and Herbert G. Fisser 2 + +Abstract. Revegetation of thousands of hectares of pre-law, abandoned bentonite minespoils in northeastern Wyoming has proven particularly difficult due to absence of topsoil and adverse physiochemical characteristics of spoil such as high clay content and sodicity. This paper presents 7th through 9th year findings of a project evaluating short and long-term effects of initially applied wood residue and N-fertilizer, and a later applied gypsum amendment on re-established vegetation. The initial benefits of higher rates of wood residue amendment (90 and 135 Mg/ha) to revegetation generally persisted through the 9th growing season, as did certain effects of initial N-fertilization within residue-amended treatments. Surface application of 56 Mg/ha of gypsum during the 6th year to ameliorate sodicity significantly enhanced plant growth during the 7th through 9th years. Findings thus supported the desirability of applying wood residue, N-fertilizer, and gypsum amendments in combination and at proper rates for effective revegetation of bentonite mine spoils. + +Additional Key Words: Soil amendments, abandoned mined lands, sodicity, gypsum, wood residues. + +Introduction + +Bentonite clay has been surface-mined extensively in northeastern Wyoming for over 50 years. Although presently mined areas are being reclaimed according to current laws, thousands of hectares of orphan spoils existed a decade ago that were abandoned in a derelict state prior to + +1 Paper presented at the 1991 National Meeting, American Society for Surface Mining and Reclamation, Durango, Colorado, May 14-17, 1991. + +2 Kellie S. Moore, Edward J. DePuit and Herbert G. Fisser are former Graduate Research Assistant, Professor and Professor, respectively, Dept. Range Management, and James L. Meining is a former Graduate Research Assistant, Dept. Plant, Soil and Insect Sciences, University of Wyoming, Laramie, WY 82071; Gerald E. Schuman is a Soil Scientist, USDA-ARS High Plains Grasslands Research Station, 8408 Hildreth Rd., Cheyenne, WY 82009 + +enactment of Wyoming's reclamation law in 1973. Natural revegetation of these lands has proven limited even after several decades (Sieg et al 1983). In light of this, reclamation of orphan bentonite spoil has been a major focus of the State of Wyoming's Abandoned Mined Land Program since 1985 (Richmond 1989). + +Several characteristics of bentonite spoil make reclamation difficult (Schuman et al 1984), including high expanding clay and soluble salts (particularly Na) content. These characteristics lead to a dispersed soil system which results in poor structure, low water infiltration, and a high runoff potential. The standard practice of topsoiling to overcome spoil problems is usually infeasible on orphan bentonite mined lands because topsoil was not salvaged during pre-law mining operations, and because topsoil borrowing from undisturbed areas often is not economically or environmentally sound (Richmond 1989). Therefore, most efforts toward reclaiming these spoils have centered upon applying various organic and/or inorganic + +Proceedings America Society of Mining and Reclamation, 1991 pp 403-412 + +DOI: 10.21000/JASMR91020403 https://doi.org/10.21000/JASMR91010403 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6b35c05e1e1c9db1f769c1d51f83d0a4bca7c9be --- /dev/null +++ b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +amendments to directly ameliorate adverse spoil attributes (Schuman and Sedbrook 1984, Schuman et al 1989, Dollhopf et al 1989, Voorhees and Uresk 1990). + +Results of a pilot study in northeastern Wyoming (Schuman and Sedbrook 1984) indicated that softwood residue ( Pinus ponderosa sawdust, bark, and chips) from local sawmills was promising as an organic amendment to improve physical conditions of bentonite spoil and enhance revegetation. The present study was based upon this premise, and was initiated in 1981 to further refine wood residue amendment rates, investigate the role and rate of concurrent nitrogen (N) fertilization, evaluate plant species suitable for revegetation of amended spoil, and determine rate of wood residue decomposition. Initial findings (Smith et al 1985, 1986; Belden et al 1990) demonstrated enhanced establishment and growth of seeded plant species with increasing rates of wood residue amendment through the 5th growing season. These beneficial responses were attributed to improved physical (water infiltration and structure) and chemical (reduced salinity) qualities of residue-amended spoil (Belden et al. 1990). Findings also supported the value of N fertilization to insure adequate N for plant growth and residue decomposition (Schuman and Belden 1991). + +Despite the rapidly-expressed benefits of wood residue amendment to reclamation, Belden et al (1990) noted an increase in spoil sodicity over time in residue-amended treatments. This was attributed to the overwhelming dominance of Na in the spoil cation pool, which resulted in increasing proportions of Na over other cations (i.e., sodium adsorption ratios [SAR]) following soluble cation leaching. The temporally increasing sodication raised concerns over negative impacts on revegetation, and led Belden et al (1990) to postulate that a calcium (Ca) amendment to reduce sodicity might be an essential complement to wood residue for successful long-term reclamation. Inorganic Ca amendments such as gypsum, calcium chloride, and phosphogypsum may reduce sodicity by replacing Na with Ca ions on cation exchange sites, thus freeing Na for downward leaching (Prather et al 1978). + +The optimum mode of Ca enrichment is to incorporate Ca amendments into the soil concurrently with wood residue at the outset of reclamation and prior to revegetation. This + +approach is presently being utilized in most abandoned bentonite reclamation programs in northeastern Wyoming (Richmond 1989). However, soil incorporation of Ca amendments on previously revegetated sites (such as the 1981 study site) would obviously damage or destroy established vegetation. Consequently, research was initiated in 1987 at the 1981 study site to determine whether gypsum could be an effective Ca amendment if applied to the soil surface without incorporation. The thesis of Meining (1991) reported edaphic responses to varied gypsum and wood residue rate treatments. The following paper will address selected, major plant responses. The vegetation-related objectives of this study included: + +1) evaluation of effects of surface-applied gypsum on productivity of seeded and non-seeded plant species, 2) determination of longer-term influence of varied wood residue rates and N-fertilization on seeded and non-seeded plant species, and 3) determination of any interactive effects among gypsum, wood residue and/or N-fertilization treatments on plant response. + +Methods and Procedures + +Experimental Design + +The project was conducted at a site 7 km northwest of Upton, in northeastern Wyoming, that was mined and abandoned without reclamation in the 1950s. Climate of the area is semiarid (363 mm annual precipitation) and continental, with roughly 60% of yearly precipitation occurring from April through July. Prior to initiation of the study in 1981, the site was nearly devoid of the sagebrush/grassland and ponderosa pine woodland vegetation characteristic of unmined rangeland in the area. Topography consisted of rolling to steep-sloped, angle-of-repose minespoil without topsoil coverage. Table 1 summarizes pretreatment spoil attributes, and reflects the problems with high clay content, salinity, and sodicity that are characteristic of bentonite spoil in this region. + +Spoils were graded to a nearly level topography in the summer of 1981. All combinations of the following treatments were then applied in a replicated split plot/split block experimental design + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..19f2f0e4ebc2939bcf9007daa0dbc6c14df7b8be --- /dev/null +++ b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +(see Smith et al 1985 for a more complete description of treatments and plot arrangement): + +1) rate of wood residue application: 0, 45, 90 and 135 Mg/ha, and + +2) rate of nitrogen fertilization: 0, 2.5, 5.0 and 7.5 kg of N/Mg of wood residue in residue-amended treatments; the non-residue amended treatment received 0, 112, 224 and 336 kg N/ha, which was equivalent to the rates of N applied on the 45 Mg/ha wood rate treatment. + +Initial results indicated that while vegetation was significantly stimulated by the lowest rates of N fertilization, little subsequent difference in plant response existed among the 3 rates of N application (Smith et al 1985). For the purposes of the present analysis, therefore, plant responses to non-N fertilization will be compared to the average of responses among the 3 N fertilization rate treatments (i.e., a non-N vs. N-fertilized treatment comparison). + +Two mixtures of seeded species (native and introduced perennial grasses) were sown on the site in 1981 to comprise a seed mix treatment (Smith et al 1985). This report will present only responses of the native mixture, since this mix was + +Table 1. Pre-treatment characteristics of bentonite spoils et Upton, Wyoming study site, 1981 (from Smith et al. 1985). + +
Spoil Attribute Mean and Standard Error
Particle Size Distribution (%): Sand 10.8 ± 0.8
Silt 29.6 ± 0.8
Clay 56.6 ± 1.1
NO3-N (mg/kg): 7.7 ± 0.4
NH4-N (mg/kg): 2.6 ± 0.1
Total Kjeldahl N (mg/kg): 751.1 ± 5.8
P (mg/kg): 8.1 ± 0.3
C (mg/kg): 10.0 ± 1.0
pH 6.8 ± 0.1
Electrical Conductivity [EC](dS/m) 13.4 ± 1.1
Sodium Adsorption Ratio [SAR]: 63.1 ± 1.2
Soluble Cations (mg/kg): Ca 187.9 ± 9.2
Mg 73.6 ± 4.2
Na 3613.7 ± 101.3
K 32.0 ± 0.8
+ +later selected to receive the gypsum treatments because of better overall response to the initial spoil amendments. The native mixture included 5 cool-season perennial grasses ('Rosana' western wheatgrass, Agropyron smithii; 'Critana' thickspike wheatgrass, A. dasystachyum; 'Revenue' slender wheatgrass, A. trachycaulum; 'Sodar' streambank wheatgrass, A. riparium; and 'Lodorm' green needlegrass, Stipa viridula) and one shrub (Nuttall saltbush, Atriplex nuttallii). This mixture was seeded at rates to yield 130 live seeds/m² for each grass species and 32 live seeds/m² for Nuttall saltbush. + +Site preparation after grading consisted of chisel plowing; application of varied wood residue and N-fertilization rate treatments (plus a uniform application of phosphorus at 90 kg/ha); and disk plowing to uniformly incorporate all residue and fertilizer amendments within the surface 30 cm. The seed mixture was subsequently sown with a grain drill in October 1981. + +In April of 1987, the study was expanded by adding gypsum as a third soil amendment treatment (see Schuman et al 1989 for full detail). Two gypsum regimes were superimposed by dividing each native species plot, and randomly designating each portion to receive gypsum at either 0 or 56 Mg/ha. The 56 Mg/ha gypsum rate supplied sufficient Ca ions to reduce the exchangeable sodium percentage (ESP) of the spoil to 15. The gypsum was surface-applied with no subsequent soil incorporation, to avoid physically disrupting previously established vegetation. + +Sampling (1988 - 1990) + +Techniques of vegetation sampling and analysis for the pre-gypsum amendment years of 1981 through 1986 were described in preceding reports (Smith et al 1985, 1986; Schuman et al 1989; Belden et al 1990). Methods and results of post-gypsum amendment soil sampling were described by Meining (1991), and will not be included in this paper. + +Vegetation was sampled from 1988 through 1990 for density, canopy cover, and aboveground biomass. Within each replicate block, 2 permanent 0.25 m² rectangular quadrat locations were established within each wood residue-fertilization-gypsum treatment combination subplot for density and canopy cover estimation. Stem density was + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fd263bfaa8539014ad92cedc17db6693593b03a7 --- /dev/null +++ b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Table 2. Main effects of wood residue rates and/or significant interactions between residue rates and N-fertilization/gypsum treatments on aboveground biomass of dominant plant growth forms, 1988-1990. ¹ + +
Growth FormYearTwo-Way Interactions With Inorganic Amendments2Wood Residue Rate (Mg/ha)
04590135
Biomass (g/m2)
PERENNIAL GRASSES1988None1 B9 B27 A44 A
1989a) Gypsum-Amended4 E12 D32 B47 A
No Gypsum1 E1 E12 D26 C
b) N-Fertilized33 C5 C26 B47 A
Non N-Fertilized1 C4 C12 BC19 B
1990N-Fertilized31 C8 C40 B76 A
Non N-Fertilized<1 C11 BC27 BC27 BC
ANNUAL FORBS1988None7 A6 A5 A2 B
1989N-Fertilized318 B12 C8 CD7 D
Non N-Fertilized28 A12 C2 D1 D
1990None59 A15 B8 BC2 C
SHRUBS1988None11 A101 A38 A43 A
1989N-Fertilized37 B35 B16 B19 B
Non N-Fertilized2 B4 B23 B83 A
1990None13 A43 A35 A54 A
+ +¹ Within growth forms, years and (if present) interactions, values followed by same letter are not significantly different at \(P \leq 0.10\). + +² Between wood residue rate and either or both N fertilization regime or gypsum regime; no significant three-way interactions among residue, fertilization and gypsum treatments occurred. + +³ Values are means among 3 rates of initial N fertilization applied in 1981. + +## Gypsum Amendment Effects + +Gypsum was surface-applied as an amendment treatment in April of 1987. Therefore, data collected in 1988, 1989, and 1990 reflect responses 1, 2, and 3 years after treatment application, respectively. Soils data of Meining (1991) demonstrated reductions in sodicity (exchangeable Na, ESP and SAR) and evidence of increased Na leaching in the upper 30 cm of gypsum-amended spoils during the 1988-1990 period. + +Aboveground biomass of seeded perennial + +grasses and non-seeded annual forbs responded positively to gypsum amendment within the first 14 months after application in 1988 (see Table 3), although gypsum responses were confounded somewhat by a two-way interaction with N-fertilization. More clearly positive effects of gypsum on herbaceous species productivity emerged in 1989 and 1990. This may have been due to the passage of additional time for fuller expression of gypsum's ameliorative effects on spoil sodicity. Gypsum has been noted to require more time for effectiveness than certain other inorganic amendments due to its relatively lower + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a51005e725c5e2614a502b7568c5006664a8ee1f --- /dev/null +++ b/outputs/multi_column/0208fbb5d6b646f972f4702428ad2cede5c5_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Table 4. Interactive canopy cover responses of dominant individual herbaceous species to wood residue and gypsum amendment treatments during the 9th (1990) growing season. 1,2 + +
Plant SpeciesGypsum RegimeWood Residue Rate (Mg/ha)
04590135
Canopy Cover (%)
Agropyron smithiiGypsum-Amended1 D9 C33 A28 A
No Gypsum1 D3 D17 B19 B
Agropyron dasystachyum + A. riparium3Gypsum-Amended1 B4 B7 AB10 A
No Gypsum1 B1 B4 B10 A
Atriplex suckleviGypsum-Amended54 A23 B6 CD6 CD
No Gypsum20 BC9 CD5 D2 D
+ +¹ Within each species, values followed by same letter are not significantly different at \(P \leq 0.10\). + +² No significant gypsum or wood residue treatment main effects nor treatment interactions occurred for cover of dominant individual shrub species in 1990. + +³ Accurate field differentiation of these 2 species was not possible. + +disappeared in the subsequent, drier year of 1990, it persisted for canopy cover of western wheatgrass, the most dominant individual perennial grass species (see Table 4). Canopy cover of the predominant annual forb species, rillscale, responded positively to gypsum amendment in 1990 only under the reduced grass competition regimes of non-residue and lightly (45 Mg/ha) residue-amended treatments (see Table 4). Responses of rillscale may have been different in absence of grass competition, since Voorhees et al (1987) noted that gypsum greatly improved production of rillscale monocultures only with concurrent application of wood residue. + +Total live biomass of shrub species was higher in the gypsum than in the non-gypsum treatment in 1988 (under both N-fertilization treatments) and in 1989 (see Table 3). This rapid and positive response of shrubs to gypsum was surprising considering the relatively slow annual growth rates of these woody species, and the anticipated undetectability of differences in current year growth between treatments due to the masking effect of antecedent live biomass produced in years preceding gypsum amendment. However, + +significant differences in shrub biomass between gypsum treatments disappeared in 1990. This may have been due to the high variability of shrub data and/or to an initial manifestation of competitive inhibition of shrubs by more gypsum-responsive perennial grasses in 1990. + +Results indicate that the effectiveness of a 1987 surface application of gypsum in reducing spoil sodicity during 1988, 1989, and 1990 (Meining 1991) induced a remarkably rapid enhancement of plant growth during these 3 years. These findings are particularly significant considering gypsum's past performance as a relatively slow-acting inorganic amendment that is most effective when soil incorporated. + +Conclusions + +Vegetation responses during the 7th through 9th years of this continuing project strongly support the longer-term benefits from high rates of wood residue amendment for revegetation of non-topsoiled bentonite mine spoil, particularly for growth of dominant seeded perennial grasses. However, data also indicated that an inorganic Ca + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0225d691d6da96027cb8edd0c41da512dd36_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0225d691d6da96027cb8edd0c41da512dd36_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..955280105071b263107c260f5e8c329cab7ac108 --- /dev/null +++ b/outputs/multi_column/0225d691d6da96027cb8edd0c41da512dd36_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +![](figure) + +# Research Article + +# DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4+CD25high FOXP3+ Regulatory T Cells but Does Not Affect Their Suppressive Capacity + +### Sija Landman ,1 Marjan Cruijsen,2 Paulo C. M. Urbano,1 Gerwin Huls,2,3 Piet E. J. van Erp,4 Esther van Rijssen,1 Irma Joosten,1 and Hans J. P. M. Koenen 1 + +1Department of Laboratory Medicine-Medical Immunology, Radboud University Medical Center (Radboudumc), Nijmegen, Netherlands 2Department of Hematology, Radboud University Medical Center (Radboudumc), Nijmegen, Netherlands 3Department of Hematology, University Medical Center Groningen, Groningen, Netherlands 4Department of Dermatology, Radboud University Medical Center (Radboudumc), Nijmegen, Netherlands + +Correspondence should be addressed to Hans J. P. M. Koenen; hans.koenen@radboudumc.nl + +Received 30 October 2017; Revised 14 February 2018; Accepted 8 March 2018; Published 15 April 2018 + +Academic Editor: Nejat K. Egilmez + +Copyright © 2018 Sija Landman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. + +Regulatory T cells (Treg) can show plasticity whereby FOXP3 expression, the master transcription factor for Treg suppressor function, is lost and proinflammatory cytokines are produced. Optimal FOXP3 expression strongly depends on hypomethylation of the FOXP3 gene. 5-Azacytidine (Aza) and its derivative 5-aza-2′-deoxycytidine (DAC) are DNA methyltransferase inhibitors (DNMTi) that are therapeutically used in hematological malignancies, which might be an attractive strategy to promote Treg stability. Previous in vitro research primarily focused on Treg induction by DAC from naïve conventional CD4+ T cells (Tconv). Here, we examined the in vitro effect of DAC on the stability and function of FACS-sorted human naturally occurring CD4+CD25high FOXP3+ Treg. We found that in vitro activation of Treg in the presence of DAC led to a significant inhibition of Treg proliferation, but not of Tconv. Although Treg activation in the presence of DAC led to increased IFNγ expression and induction of a Thelper-1 phenotype, the Treg maintained their suppressive capacity. DAC also induced a trend towards increased IL-10 expression. In vivo studies in patients with hematological malignancies that were treated with 5-azacytidine (Vidaza) supported the in vitro findings. In conclusion, despite its potential to increase IFNγ expression, DAC does preserve the suppressor phenotype of naturally occurring Treg. + +## 1. Introduction + +Regulatory T cells (Treg) are important for homeostasis of immune-related pathologies and are thought to promote chronic inflammation [9–12]. Demethylating agents, such as the DNA methyltransferase inhibitor (DNMTi) + +of the immune system [1]. Immune regulation by Treg 5-azacytidine (Vidaza, Aza) and its derivative 5-aza 2′-deox-depends on the stability of these cells [1, 2], which in turn is controlled by stable expression of the transcription factor FOXP3 [3]. In the past, we have shown that Treg reveal plasticity as indicated by loss of FOXP3 expression and gain of proinflammatory cytokine (IL-17a, IFNγ) production [4]. Stable FOXP3 expression requires hypomethylation of + +ycytidine (decitabine, DAC), are used in the treatment of hematological malignancies and seem an attractive therapeutic strategy to promote Treg stability. Aza and DAC have related mechanisms of action, including depletion of DNMTs and hypomethylation of DNA [13, 14]. Aza/DAC shows immunomodulatory potential in vitro and in vivo and have CpG-rich regions of the FOXP3 gene, which is known as Treg-specific demethylated region (TSDR) [5–8]. Treg instability and plasticity have been demonstrated in a number + +been shown to induce demethylation of the FOXP3 gene [15, 16]. Administration of DAC in experimental mouse models of inflammation (lung inflammation [17–19], diabetes diff --git a/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..37ff1ec302c5929bf4dfc578d4e1ce78898f5cdf --- /dev/null +++ b/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +# Coupling of Methanothermobacter thermautotrophicus Methane Formation and Growth in Fed-Batch and Continuous Cultures under Different H2 Gassing Regimens† + +Linda M. I. de Poorter, Wim J. Geerts, and Jan T. Keltjens* Department of Microbiology, Faculty of Science, Radboud University of Nijmegen, Nijmegen, The Netherlands + +Received 8 August 2006/Accepted 16 November 2006 + +In nature, H2- and CO2-utilizing methanogenic archaea have to couple the processes of methanogenesis and autotrophic growth under highly variable conditions with respect to the supply and concentration of their energy source, hydrogen. To study the hydrogen-dependent coupling between methanogenesis and growth, Methanothermobacter thermautotrophicus was cultured in a fed-batch fermentor and in a chemostat under different 80% H2–20% CO2 gassing regimens while we continuously monitored the dissolved hydrogen partial pressures (pH2). In the fed-batch system, in which the conditions continuously changed the uptake rates by the growing biomass, the organism displayed a complex and yet defined growth behavior, comprising the consecutive lag, exponential, and linear growth phases. It was found that the in situ hydrogen concentration affected the coupling between methanogenesis and growth in at least two respects. (i) The microorganism could adopt two distinct theoretical maximal growth yields (YCH4 max), notably approximately 3 and 7 g (dry weight) of methane formed mol-1, for growth under low (pH2 < 12 kPa)- and high-hydrogen conditions, respectively. The distinct values can be understood from a theoretical analysis of the process of methanogenesis presented in the supplemental material associated with this study. (ii) The in situ hydrogen concentration affected the “specific maintenance” requirements or, more likely, the degree of proton leakage and proton slippage processes. At low pH2 values, the “specific maintenance” diminished and the specific growth yields approached YCH4 max, indicating that growth and methanogenesis became fully coupled. + +Most methanogenic archaea, including the Methanothermobacter thermautrophicus used in the present study, derive their energy for autotrophic growth from the H2-dependent reduction of CO2 into methane. The pathways of methane formation, CO2 fixation, and ATP synthesis are highly conserved among the different H2-utilizing (hydrogenotrophic) methanogens (for reviews, see references 5, 6, 9, and 32 and additional information in the supplemental material). Nevertheless, different species display remarkable differences in specific growth yields (YCH4), i.e., the amount of biomass formed per mole of methane produced at a given growth condition (Table 1). YCH4 values can be variable for a given species. Even maximal growth yields (YCH4 max) seem to differ. YCH4 max represents the theoretical maximal growth yield that would be obtained if methanogenesis and growth are fully coupled. Methanogens have to couple the processes of energy generation (methanogenesis) and biomass formation under highly diverse concentrations of their energy source, hydrogen. In environments such as anaerobic sediments and sewage digestors, hydrogen formed by obligate proton reducers is available at only very low levels (11, 37). In contrast, hydrogen concentrations can be high at sites where methanogens obtain the gas from H2-producing fermentative microorganisms (29, 37). Un- + +* Corresponding author. Mailing address: Department of Microbiology, Faculty of Science, Radboud University of Nijmegen, Toernooiveld 1, NL-6525 ED Nijmegen, The Netherlands. Phone: 31-24-3653437. Fax: 31-24-3652830. E-mail: J.Keltjens@science.ru.nl. † Supplemental material for this article may be found at http://aem .asm.org/. Published ahead of print on 1 December 2006. + +der laboratory conditions, the hydrogen availability of the cells depends on the gassing rates applied and the hydrogen-mass transfer capacity of the fermentative devices. In fed-batch systems, dissolved hydrogen partial pressures (pH2) continuously change over time as the result of increasing consumption rates by a growing biomass. Many authors observed that specific growth yields were relatively low when growth proceeded under hydrogen excess and that yields were highest under conditions of hydrogen limitation (7, 8, 12, 14, 18, 24, 27, 33, 34). Apparently, the degree of coupling between methanogenesis and growth depends on the in situ hydrogen concentration. In these studies, hydrogen-excess and hydrogen-limited conditions were imposed by changing the gassing rates or medium agitation. Unfortunately, with notable exceptions (12, 24), the hydrogen concentrations were not actually measured. To investigate how methanogenesis and the growth of M. thermautotrophicus were coupled, we cultured the organism under a variety of hydrogen gassing regimens, while continuously recording the pH2 value. We did so both in a fed-batch fermentor system, where conditions continuously change, and under the controlled conditions of a chemostat. In the fed-batch system the organism displayed a complex growth behavior comprising different growth phases that were each characterized by the distinct way that specific growth rates, growth yields, and methane-forming activities were interrelated. Both the fed-batch and the chemostat studies substantiated previous suggestions that specific growth yields depended on the dissolved hydrogen partial pressures and increased with decreasing pH2 values. Quite remarkably, our work also suggests that M. thermautotrophicus may adopt two different maximal growth yields for growth under low- and high-hydrogen conditions. diff --git a/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4df75784ca6420ee207d097da4ff1c76a9e6e528 --- /dev/null +++ b/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,9 @@ +![Three panels showing time series plots of various biochemical and gas production variables. Panel A shows OD_600 (diamonds), V_H2 (squares), and ρ_H2 (circles) versus time (hours). Panel B shows ρ_H2 (circles), q_CH4 (triangles), Y_CH4 (dots), and μ (squares) versus time (hours). Panel C shows q_CH4 (mol.g^{-1}.h^{-1}) versus μ (h^{-1}).](figure)[^inferred] + +![Three panels showing time series plots of various biochemical and gas production variables. Panel A shows OD_600 (diamonds), V_H2 (squares), and ρ_H2 (circles) versus time (hours). Panel B shows ρ_H2 (circles), q_CH4 (triangles), Y_CH4 (dots), and μ (squares) versus time (hours). Panel C shows q_CH4 (mol.g^{-1}.h^{-1}) versus μ (h^{-1}).](figure)[^inferred] + +FIG. 2. Growth of M. thermautotrophicus in a fed-batch reactor at high gassing rate. The organism was cultured in 2.5 liters of mineral medium at a constant gassing rate of 428 ml \(\min^{-1}\) with 80% H2–20% CO2 (vol/vol). Measurements started (t 0 h) 8 h after adjustment of the gassing rate. Panels A to C and symbols are as described in the legend to Fig. 1. + +dissolved hydrogen partial pressure steadily decreased to become as low as 1 kPa. Before that time, the hydrogen consumption rate had become constant (84 ml \(\min^{-1})\), and 98% of the gas ended up in methane. When the pH2 had reached the minimum at t 10 h, the optical density increased linearly over time. This period is denoted as the linear phase. Apparently, growth now became limited by the H2 supply. To test this, the organism was grown at a higher gassing rate (428 ml \(\min^{-1})\). The same growth behavior was found (Fig. 2A). Quite remarkably, pH2 did not drop to low values during the linear growth stage, but it was maintained as high as 29 kPa. Again, the hydrogen consumption rate became constant \((_{\mathrm{H}_{2}}275\) ml \(\min^{-1})\), but the gas was only partly utilized. Further experiments showed that the pH2 values could be manipulated by the H2–CO2 gassing regimen (Table 3). Depending on the hydrogen mass transfer characteristics, i.e., gassing rate/culture volume ratio and mixing intensity (number of impellers), steady pH2 values were obtained during the linear growth phase that ranged between 1 and 59 kPa. Linear growth could proceed for prolonged periods of time (at least 72 h), at which OD600 values of up to 7 to 10 were obtained (data not shown). Hydrogen consumption and methane production rates, as well as dissolved hydrogen partial pressures, however, remained constant throughout the whole period of linear growth. Growth rates, growth yields, and methane-forming activities in the fed-batch fermentor system. As noted above, three consecutive growth phases could be discerned, notably the lag, exponential, and linear phases. The exponential phase is usually determined from the straight section of the graphs in which the (natural) logarithm of biomass (or OD) is plotted against + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..dcc7e383190ccff6df64d9866ff0d8ff401eb303 --- /dev/null +++ b/outputs/multi_column/027880a87e3c2ad4cf8c05f477597c0c6da7_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,144 @@ +TABLE 3. Growth properties of Methanothermobacter thermautotrophicus in the fed-batch fermentora + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Culture conditionExponential phaseLinear phase
vin (ml min-1)Vol (liter)Modeex (h-1)qCH4 max qCH4YCH4 maxpH2 lin (kPa)YCH4 lin
(mol g-1 h-1)(mol g-1 h-1)(g mol-1 CH4)(g mol-1 CH4)
1072.5b0.250.1670.0793.1513.00
2142.5a0.220.1440.0703.1513.20
b0.240.1270.0347.0542.20
b0.250.1610.0376.7542.00
4282.5a0.230.1740.0346.7061.70
b0.230.1770.0356.70291.65
2.0b0.220.1780.0336.70491.55
1.5b0.220.1880.0336.70591.40
+ +a M. thermautotrophicus was cultured at the indicated gassing rates and culture volumes. Abbreviations: vin, gassing rate (80% H2–20% CO2 vol/vol \();_{\text{ex}}\), specific growth rate during exponential growth; qCH4 max, maximal specific methane-forming activity in the exponential phase; \(q_{\text{CH}_{4}}\), difference between the maximal and minimal specific methane-forming activity in the exponential phase; YCH4 max, theoretical maximal growth yield; pH2 lin, dissolved hydrogen partial pressure during linear growth; YCH4 lin, specific growth yield during linear growth. Modes: a, one impeller mounted; b, two impellers mounted. YCH4 max and YCH4 lin were calculated as specified in the text and in the supplemental material (1). + +time, the slope representing the specific growth rate during the exponential phase \((_{\text{ex}})\) (see also the supplemental material [1]). Deviation from linearity was always seen in the period preceding the exponential phase (lag period). Here, perfect straight lines were obtained, if the ln(OD600) values were plotted against the squared times (Fig. 3A, inset). As outlined in in the supplemental material, this implies that the specific growth during the lag phase increases linearly in time (Fig. 1B and 2B). Also, the specific methane-forming activity increased linearly in time during this period (Fig. 1B and 2B). In fact, a plot of the qCH4 values against the corresponding values showed a direct proportional relationship between both parameters, the slope representing the reciprocal of the specific growth yield (YCH4), which now was constant (Fig. 1C, 2C, and 3A). The physiological meaning of these findings is that, after inoculation, cells adapt to the new growth condition by the uniform and concerted acceleration of their specific growth rate and specific methane-forming activity in a way that YCH4 remains fixed. The specific growth rates became maximal at the entry of the exponential stage and remained constant throughout the particular stage (Fig. 1B, 2B, and 3A). The values did not significantly differ among the various gassing regimens (0.22 to 0.25 \(\mathrm{h}^{-1}\); doubling times of 2.8 to 3.1 h) (Table 3). However, the qCH4 was not constant. Specific methane-forming activities initially increased to a maximum and declined thereafter. The decline occurred concomitant with the decrease in the dissolved hydrogen partial pressures, resulting from the increasing hydrogen uptake rates by the growing biomass (Fig. 1 and 2 and Table 3). Apparently, the physiology of the cells continuously changed, even at a constant growth rate. After exponential growth, the cells entered the linear phase. During this stage, the specific growth rates and specific methane-forming activities, calculated by using the equations S.5 and S.6, respectively, in the supplemental material(1), de- + +![Graph A showing q^{CH4} (mol.g^{-1}.h^{-1}) vs \mu (h^{-1}), with inset of ln(OD_{600}) vs time^2 (h^2), and vertical line at \mu_{ex}.](figure)[^inferred] + +![Graph A showing q^{CH4} (mol.g^{-1}.h^{-1}) vs \mu (h^{-1}), with inset of ln(OD_{600}) vs time^2 (h^2), and vertical line at \mu_{ex}.](figure)[^inferred] + +FIG. 3. Relationship between the specific rates of methanogenesis and specific growth rates during the lag (A), linear (B), and exponential growth phases. M. thermautotrophicus was cultured in 2.5 (A) and 1.5 (B) liters of mineral medium at a constant gassing rate of 428 ml \(\min^{-1}\) in 80% H2–20% CO2 (vol/vol). Measurements started 5 h + +creased in parallel (Fig. 1B and 2B). Moreover, \(q_{\text{CH}_{4}}-\text{versus}-\) (A) and 8 h (B) after adjustment of the gassing rates. In the inset of + +plots showed the direct proportional relationship as expected + +from equation S.8 (Fig. 1C, 2C, and 3B). The slope of the plots, + +which equals the reciprocal of the specific growth yield (equation S.8), varied with the dissolved hydrogen partial pressure + +Fig. 3A, the ln(OD600) is plotted versus the squared time after inoculation. Lag (), exponential (Œ), and linear (}) growth stages are as + +indicated. \(_{\text{ex}}\), specific growth rate during the exponential phase; + +qCH4, change between the maximal and minimal specific activities during the exponential phase. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..07362a76a9d0f258f1fd766325405c7b841e7de2 --- /dev/null +++ b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +![](figure) + +# Impact of Hypertension on Type 2 Diabetes in Mysore Population of South India* + +Mohammed Salman1,2#, Shruti Dasgupta1,3, Cletus J. M. D’Souza1,2, D. Xaviour1, B. V. Raviprasad1, Jayashankar Rao1, G. L. Lakshmi1 1Anthropological Survey of India, Southern Regional Centre, Mysore, India; 2Department of Studies in Biochemistry, University of Mysore, Mysore, India; 3Department of Studies in Biotechnology, University of Mysore, Mysore, India. + +Email: #Salman.biochem@gmail.com + +Received October 24th, 2013; revised November 20th, 2013; accepted December 5th, 2013 + +Copyright © 2013 Mohammed Salman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. + +### ABSTRACT + +Objective: The study aims to explore the prevalence of hypertension and its impact on Type 2 diabetes in a Mysore population of the Indian subcontinent. Methods: 636 participants volunteered for the study. Anthropometric measurements and blood pressure were recorded while plasma was analyzed for biochemical markers. The IDF and JNC 7 diagnostic criteria were followed to define diabetes and hypertension. Statistical Analyses: One-way analysis of variance, \(\chi^{2}-\)test and Logistic regression analysis were performed to assess differences of the mean, proportion and the independent effect of hypertension on the development of type 2 diabetes. Results: Hypertension was observed to be prevalent in 37.1% of the studied population with an insignificant gender difference. Rate of occurrence of hypertensives was found to be significantly higher in type 2 diabetes (51.9%), obese subjects (45.2%), long-term smokers (49%) and alcohol addicts (48%) than control groups. The risk of development of diabetes was significantly higher in hypertensives than normotensive. However, when creatinine and blood urea nitrogen were included in the model, the significance was nullified. Conclusions: The prevalence of type 2 diabetes and hypertension is increasing at an alarming rate. This study reveals that the significance of hypertension as a parameter in predicting the risk of type 2 diabetes was influenced by the renal function and lipid profile. + +Keywords: Hypertension; Type 2 Diabetes; Prevalence; Kidney Dysfunction; Mortality; Mysore Population; India + +## 1. Introduction + +The incidence of Type 2 Diabetes (T2D) is increasing globally from 2.8% in 2000 to 4.4% in 2030 [1]. The prevalence of T2D in Asian Indians ranges from 2.7% in rural India to 14% in urban India. India has the highest number of diabetes in the world [2,3]. The National Urban Diabetes Survey reported 12.1% of diabetes and 14% of impaired glucose tolerance [4]. The prevalence of hypertension (HTN) among adults is expected to rise by 60% resulting in a total of 1.56 billion affected individuals by 2025. Approximately 70% of diabetics are hypertensives, as diabetics are prone to HTN twice more likely than normoglycemic individuals [5]. Similarly, the presence of HTN precedes the onset of diabetes mellitus (DM) [6,7]; and among diabetics, HTN develops into diabetes + +*Competing Interests: the author(s) declare that they have no competing interests. #Corresponding author. + +nephropathy and retinopathy. The co-occurrence of HTN and T2D affects up to 60% of patients leading to higher risk of developing cardiovascular morbidity and mortality [8]. Though cardiovascular risks are common in both, in conjunction they accelerate cardiac, cerebral and renal dysfunctions [9]. The United Kingdom Prospective Diabetes Study (UKPDS) revealed that blood pressure control helps to avoid cardiovascular complications in patients with T2D [10]. The decrease in mean systolic blood pressure by 10 mm/Hg reduces the risks of developing complications in diabetes by 12%, mortality by 15%, myocardial infraction by 11% and microvascular complications by 13% among diabetics respectively [11]. The prevalence varies across different ethnic and religious groups in Asia; the co-occurrence of diabetes with HTN shows an increasing trend and has become an epidemic of a great concern [12]. About 50% of diabetes cases in India show the co-occurrence of HTN [13,14]. diff --git a/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..dac631b0698060f1560fd86b83932bb303b3e5c6 --- /dev/null +++ b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +Diabetes in other Asian countries such as Saudi Arabia (53%) [15,16], Jordan (72.4%) [17], Oman (21.5%), Turkey (32%), Bahrain (38%) and Taiwan (39%) [18-21] also shows a similar trend. In addition, studies reported higher tendency of HTN among UK Afro-Caribbean (82%) [22], UK Caucasian (74%), Italian (74.4%) and Spanish diabetes (73%) [23-25]. Few epidemiological studies asserting incidence rates of T2D and HTN have been carried out in various sectors of Karnataka. In the rural population of Davanagere, 18.3% of HTN has been reported, where males recorded a higher prevalence rate (19.1%) than females (17.5%) [26]. Heritability of HTN in families of Tumkur population was reported, wherein the young normotensive with a positive family history of HTN had significantly higher blood pressure [27]. In Karnataka, the prevalence of T2D has been observed to be 3.77% of Suttur population [28], 10.0% in Kolar population [29], 16% of the Udupi population [30] and 17.3% in Dharwad urban population [31]. The incidence of obesity among T2D of Mysore population was reported [32], while the awareness of diabetes and their attitude to patients of Bijapur have been reported [33]. But there is no known record of the prevalence of HTN among T2D or vice versa, implying how frequent HTN exacerbates T2D in southern India. Currently, there are limited epidemiological studies edifying the relationship between T2D and HTN in Indian context. There is an ongoing debate regarding the consideration of high blood pressure over other metabolic components (conjointly involved in T2D and HTN), as a predictor of T2D in Indians. Further, social and cultural diversity in India necessitates the exploration of the mentioned relationship in various sections of this country. Therefore we hypothesize that the risk of incidence of T2D is higher in the subjects with HTN. The present study aims to assess the prevalence of HTN among T2D subjects and its contribution in the occurrence of T2D in Mysore population of Karnataka in South India. + +## 2. Materials and Methods + +### 2.1. Study Population + +This case-control study was conducted among participants in the diabetes health check-up programs organized by Amrita Kripa Polyclinic and Lion’s Club of Mysore + +(R) in Mysore district of Karnataka State, India, during 2010 to 2011 including both non-diabetes and diabetes patients, without any mental impairment. + +### 2.2. Sample Size + +A total of 654 subjects volunteered and gave consent to participate in the study, out of which 636 were included in the study. The subjects including 343 males and 293 females, aged between 30 - 80 years were enrolled for the study. Subjects with abnormal renal or chronic liver dysfunction were excluded from the study. + +### 2.3. Sampling Procedure + +The study protocol was reviewed and approved by the Institutional Ethics Committee, Kolkata and also the Ethical Committee of University of Mysore. Informed consents were obtained from each participant in the study. The study was conducted according to the ethical guidelines for biomedical research on human populations (http://icmr.nic.in/ethical_guidelines, ICMR 7). Each participant of the study was about 12 hours of fasting period before the collection of blood. 5 ml blood sample was collected in 10 ml BD vacutainer by a phlebotomist, stored at 4˚C and transported to the laboratory immediately for further processing. Postprandial plasma glucose was measured after 2 hours of administering 75-grams of glucose to the subjects (OGTT, WHO, 1999). + +### 2.4. Data Collection + +Questionnaire: Data was collected on standardized questionnaire that included personal information, lifestyle, habitual behaviors (smoking and alcohol intake), clinical history of associated complications and blood pressure was recorded under the supervision of a physician. Anthropometry: Height, weight, waist and hip circumference were measured by physical anthropologists using anthropometer (Holtaine, UK) and digital weighing machine (Tanita Corporation, Tokyo, Japan) as per WHO international manual [34]. Waist circumference (WC) was measured at the midpoint at the bottom of the rib cage and the top of the lateral border of the iliac crest during minimal respiration. Laboratory Examination: Fasting plasma glucose (FPG), Glycated Haemoglobin (HbA1c), High-density lipoprotein (HDL), Low-density lipoprotein (LDL), Total Cholesterol (CHO), Triglycerides (TRIG), Creatinine (CRE), Blood urea nitrogen (BUN) and Postprandial glucose (PPG) were measured on Auto analyzer EM 360 (Transasia, ERBA Mannheim, Germany). Operational Definitions: Body mass index (BMI) was calculated as weight in kilograms divided by the squared value of height in meters (kg/m2). BMI was categorized as normal (<25 kg/m2), overweight (>25 and < 30 kg/m2), and obese (>30 kg/m2) [35]. Blood pressure (Systolic and Diastolic) of each subject was measured using a standardized sphygmomanometer (Elko, India), in supine position. An average of two readings of both systolic (SBP) and diastolic blood pressure (DBP) was taken. HTN was defined following the criteria of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC 7 diff --git a/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..59d3d0be0ad951459763d2ae3ad82ed913f159c0 --- /dev/null +++ b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,312 @@ +criteria) [36]. Participants were divided (as per their baseline BP) into, normotensive (SBP < 120 mmHg and DBP < 80 mmHg), Pre-hypertensive (SBP 120 - 140 mmHg and DBP 80 - 90 mmHg) and Hypertensive (SBP > 140 mmHg and/ or DBP > 90 mmHg), or presently taking anti-hypertensive medication. Further, hypertensives (presently taking anti-hypertensive medication or/ and with a history of HTN diagnosed by a medical physician) including the pre hypertensive were combined in one group opposed to normotensive controls. Self reported cases and individuals with FPG > 126 mg/dl and PGLU > 200 mg/dl were defined as diabetes [37]. Diabetics under treatment and long term management of blood glucose were defined as controlled diabetes with HbA1c values 6% - 8%. On the contrary above 8% were considered uncontrolled diabetes [38]. All self-reported cases were further validated by medical record review and supplementary questionnaires. + +### 2.5. Statistical Analysis + +motensives, resulting into four groups in total. The results have been reported as mean ± standard deviation. One-way analysis of variance (ANOVA) was used to analyze the statistical differences in the mean of various parameters between the groups. \(\chi^{2}-\)test was used to compare the proportion of the subjects between different dichotomized variables. Logistic regression analysis was performed to assess the independent effect of hypertensive status on the odds of occurrence of diabetes, after adjusting for confounders. Statistical analyses were performed using SPSS version 12.0 software (SPSS, Chicago, IL, USA). All the reported P-values were two-tailed, and those less than 0.05 were considered statistically significant. + +## 3. Results + +Table 1 shows the distribution of HTN across sex, age groups, diabetes status and addiction habits. The overall prevalence rate of HTN was found to be 37.1%, 33.8% of male and 41% in females. However, the intergroup dif- + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
The analysis has been carried out after segregating the cases and controls further into hypertensives and nor-Table 1. Distribution of hypertension across age, gender, BMI, habits and clinical history.NormotensiveHypertensiveTotalference is statistically similar (P > 0.05). Among differ-ent age groups, the rate of HTN increased with age from P value
VariablesCategory
N%N%N%
Type 2 Diabetes14248.115351.9295100
Diabetes status<0.001
Non Diabetes25875.78324.3341100
Female1735912041293100
Sex0.63
Male22766.211633.8343100
30 - 397986.81213.291100
40 - 4914176.24423.8185100
50 - 596750.86549.2132100
Age groups<0.001
60 - 697047.67752.4147100
70 - 793450345068100
80+969.2430.813100
Normal (<25)17969.67830.4257100
BMI groupsOverweight (25 - 30)15859.810640.22641000.009
Obese (>30)6554.85345.2118100
Yes7671.73028.3106100
SmokingNo29662.317937.74751000.03
Quit2850.92749.155100
Yes10067.64832.4148100
Alcohol intakeNo2876217638463100NS
Quit1352124825100
<6%27071.810628.2376100
Glycated6% - 8%8750.98449.1171100<0.001
haemoglobin A1c>8%4348.34651.789100
Total40062.923637.1636100
diff --git a/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..72a34dd5a344bcc9357b21ba2c9482b5019a0a58 --- /dev/null +++ b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,134 @@ +30 - 69 years and then gradually decreased in subjects of 70 years and above, and the trend was found to be significant (P < 0.001). Unconventionally, HTN was significantly less prevalent among smokers than nonsmokers whereas long term ex-smokers showed the highest prevalence (P < 0.05). A similar trend was observed among alcoholics but was found to be statistically insignificant. Obese subjects were observed to have significantly (P < 0.01) higher prevalence rate of HTN (45.2%) than overweight (40.2%) and normal (30.2%) subjects. HTN was found to be more prevalent (P < 0.001) among diabetics (51.9%) than non-diabetics (24.3%). This was further substantiated by the significantly (P < 0.001) higher prevalence rates among uncontrolled diabetes (51.7%) and controlled diabetes (49.1%) subjects than non-diabetic subjects (28.2%) as categorized by the HbA1c levels. The variables are described in Table 2 after classifying the subjects into four groups based on clinical history of diabetes and/or HTN. HTN was more prevalent in subjects of the older age group, irrespective of the presence or absence of T2D. Both diabetes normotensive and hypertensive subjects were observed to have a significantly higher waist circumference than non-diabetic normotensive subjects. Individuals affected by both of the mentioned disorders had higher BMI and CRE levels than normal controls. As anticipated, both systolic and diastolic blood pressure was higher among hypertensive groups than normotensive. Fasting glucose, postprandial glucose, glycated haemoglobin and triglyceride levels were significantly higher in the diabetes groups, irrespective of HTN. On the contrary, HDL levels were found to be low in the diabetes subjects. Levels of BUN were found to be significantly higher in diabetes hypertensives when compared to diabetes normotensive. CHO and LDL levels showed no significant difference between the groups. The influence of HTN on risk for development of T2D was analyzed based on HTN status after adjusting the probable cofounder and has been depicted in Table 3. The crude odds of occurrence of T2D due to HTN was 3.349 (P < 0.0001). Although the odds ratio was reduced after adjusting for the confounders; age, sex, smoking, alcoholism, BMI yet the level of significance was constant. The significance levels were reduced to P < 0.05 after the inclusion of FPG, PPG and HbA1c to the previously mentioned models. Though the inclusion of CRE and BUN in the model distorted the significance, but the significance completely disappeared when adjusted for TRIG, CHO, LDL and HDL. When possible confounders were controlled, the odds ratio was found to be 1.45 and was observed to be insignificant. The confounding variables that were found to be significant on inclusion of all variables in the model were Age (OR = 1.053, P = + +Table 2. Characteristics of the subjects grouped based on presence or absence of diabetes and hypertension. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Nondiabetic hypertensiveNondiabetic normotensive
BiomarkerDiabetic hypertensiveDiabetic normotensive
Mean ± S.DMean ± S.DMean ± S.DMean ± S.D
N = 153N = 142N = 83N = 258
Age (years)59.04 ± 10.50*#54.26 ± 12.49*56.34 ± 11.65*48.33 ± 12.81
Waist (cm)92.83 ± 11.45*^89.98 ± 12.51*88.44 ± 11.1886.21 ± 11.05
Body mass index (kg/m)227.37 ± 4.51*26.04 ± 4.2526.71 ± 5.1825.48 ± 4.55
Systolic blood pressure (mmHg)152.51 ± 15.68*#120.86 ± 12.97^153.88 ± 19.25*110.87 ± 12.11
Diastolic blood pressure (mmHg)92.48 ± 12.13*#82.56 ± 10.79^96.07 ± 11.71*80.08 ± 9.93
Fasting glucose (mg/dl)142.56 ± 59.19*^145.44 ± 58.93*^90.20 ± 11.1788.45 ± 9.97
Postprandial glucose (mg/dl)228.16 ± 97.34*^228.57 ± 93.62*^115.71 ± 24.45109.39 ± 22.71
Triglyceride (mg/dl)184.13 ±111.94*^186.65 ±105.48*^149.05 ± 85.89143.86 ± 91.58
Cholesterol (mg/dl)175.18 ± 45.78174.06 ± 51.09171.78 ± 49.75168.58 ± 47.08
High density lipoprotein (mg/dl)44.74 ± 9.95*^47.09 ± 10.72*^50.49 ± 7.9550.08 ± 8.31
Low density lipoprotein (mg/dl)101.79 ± 23.63102.70 ± 22.15100 ± 21.7698.05 ± 20.42
Creatinine (mg/dl)1.05 ± 0.49*0.99 ± 0.320.98 ± 0.360.95 ± 0.32
Blood urea nitrogen (mg/dl)10.30 ± 4.1#9.12 ± 39.78 ± 3.249.43 ± 3.32
Glycated haemoglobin A1c (%)7.45 ± 2.09*^7.25 ± 2.13*^5.11 ± 1.364.95 ± 1.06
+ +*P < 0.05 as compared to nondiabetes normotensive. ^#P < 0.05 as compared to diabetes normotensive. P < 0.05 as compared to nondiabetes hypertensive. diff --git a/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..35252704fd81256cbff5b0fe3f037fdbcc918ff2 --- /dev/null +++ b/outputs/multi_column/027c390510b2fd3364f5a382f2bc304af018_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,45 @@ +[23] V. Baskar, D. Kamalakannan, M. R. Holland and B. M. Singh, “The Prevalence of Hypertension and Utilization of Antihypertensive Therapy in a District Diabetes Population,” Diabetes Care, Vol. 25, No. 11, 2002, pp. 2107-2108. http://dx.doi.org/10.2337/diacare.25.11.2107 + +[24] M. Comaschi, C. Coscelli, D. Cucinotta, P. Malini, E. Manzato and A. Nicolucci, “Cardiovascular Risk Factors and Metabolic Control in Type 2 Diabetic Subjects Attending Outpatient Clinics in Italy: The SFIDA (Survey of Risk Factors in Italian Diabetic Subjects by AMD) Study,” Nutrition, Metabolism and Cardiovascular Diseases, Vol. 15, No. 3, 2005, pp. 204-211. http://dx.doi.org/10.1016/j.numecd.2004.07.003 + +[25] F. J. Del Cañizo-Gómez and M. N. Moreira-Andrés, “Cardiovascular Risk Factors in Patients with Type 2 Diabetes. Do We Follow the Guidelines?” Diabetes Research and Clinical Practice, Vol. 65, No 2, 2004, pp. 125-133. http://dx.doi.org/10.1016/j.diabres.2003.12.002 + +[26] B. Y. Yuvraj, M. R. Nagendragowda and A. G. Umakantha, “Pevalence, Awaeness, Treatment and Control of Hypertension in Rural Areas of Davanagere,” Indian Journal of Community Medicine, Vol. 35, No. 1, 2010, pp. 138-241. http://dx.doi.org/10.4103/0970-0218.62578 + +[27] G. Dayananda and M. Niranjan, “Blood Pressure Changes in Normotensive Subjects with and without Family History of Hypertension,” Journal of Physiology and Biomedical Sciences, Vol. 22, No. 1, 2009, pp. 35-37. + +[28] H. Basavanagowdappa, A. K. Prabhakar, P. Prasannaraj, K. C. Gurudev, Virupaksha and Suma, “Study of Prevalence of Diabetes Mellitus and Impaired Fasting Glucose in a Rural Population,” International Journal of Diabetes Developing Countries, Vol. 25, No. 4, 2005, pp. 98-101. http://dx.doi.org/10.4103/0973-3930.27012 + +[29] C. Muninarayana, G. Balachandra, S. G. Hiremath, I. Krishna and N. S. Anil, “Prevalence and Awareness Regarding Diabetes Mellitus in Rural Tamaka, Kolar,” International Journal of Diabetes Developing Countries, Vol. 30, No. 1, 2010, pp. 18-31. + +[30] C. R. Rao, V. G. Kamath, A. Shetty and A. Kamath, “A Study on the Prevalence of Type 2 Diabetes in Coastal Karnataka,” International Journal of Diabetes Developing Countries, Vol. 30, No. 2, 2010, pp. 80-85. + +[31] S. Pushpa Patil, R. Umesh Dixit and B. H. Dhruvkumar, “Study of Diabetes in Dharwad—An Urban Area in India,” Indian Journal of Science and Technology, Vol. 4, No. 11, 2011, pp. 1481-1483. + +[32] M. A. Shekar, H. M. Somashekar and B. S. Vishwanath, “Study of Incidence of Obesity in Newly Diagnosed Type + +2 Diabetics Using Anthropometric Measurements,” International Journal of Diabetes Developing Countries, Vol. 25, No. 4, 2005, pp. 102-104. + +[33] C. K. Priyankaraj and M. M. Angadi, “Hospital-Based KAP Study on Diabetes in Bijapur, Karnataka,” Indian Journal of Medical Specialities, Vol. 1, No. 2, 2010, pp. 80-83. + +[34] World Health Organization, “Physical Status: The Use and Interpretation of Anthropometry. Report of the WHO Expert Committee,” World Health Organization Technical Report Series, Vol. 854, Geneva, 1995, pp. 1-416. + +[35] World Health Organization, “Obesity: Preventing and Managing the Global Epidemic. Report of a WHO Consultation,” World Health Organization Technical Report Series, Vol. 894, 2000, pp. 1-253. + +[36] A. V. Chobanian, G. L. Bakris, H. R. Black, W. C. Cush-man, L. A. Green, J. L. Izzo Jr., D. W. Jones, B. J. Materson, S. Oparil, J. T. Wright Jr. and E. J. Roccella, “The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The JNC 7 Report,” Journal of the American Medical Association, Vol. 289, No. 19, 2003, pp. 2560-2572. http://dx.doi.org/10.1001/jama.289.19.2560 + +[37] K. G. Alberti and P. Z. Zimmet, “Definition, Diagnosis and Classification of Diabetes Mellitus and Its Complications. Part 1: Diagnosis and Classification of Diabetes Mellitus Provisional Report of a WHO Consultation,” Diabetic Medicine, Vol. 15, No. 7, 1998, pp. 539-553. http://dx.doi.org/10.1002/(SICI)1096-9136(199807)15:7< 539::AID-DIA668>3.0.CO;2-S + +[38] D. M. Nathan, D. E. Singer, K. Hurxthal and J. D. Goodson, “The Clinical Information Value of the Glycosylated Hemoglobin Assay,” New England Journal of Medicine, Vol. 310, No. 6, 1984, pp. 341-346. http://dx.doi.org/10.1056/NEJM198402093100602 + +[39] S. R. Joshi, B. Saboo, M. Vadivale, S. I. Dani, A. Mithal, U. Kaul, M. Badgandi, S. S. Iyengar, V. Viswanathan, N. Sivakadaksham, P. S. Chattopadhyaya, A. D. Biswas, S. Jindal, I.. A. Khan, B. K. Sethi, V. D. Rao and J. J. Dalal, “SITE Investigators Prevalence of Diagnosed and Undiagnosed Diabetes and Hypertension in India Results from the Screening India’s Twin Epidemic (SITE) Study,” Diabetes Technology and Therapeutics, Vol. 14, No. 1, 2012, pp. 8-15. http://dx.doi.org/10.1089/dia.2011.0243 + +[40] I. H. de Boer, B. Kestenbaum, T. C. Rue, M. W. Steffes, P. A. Cleary, M. E. Molitch, J. M. Lachin, N. S. Weiss and J. D. Brunzell, “Insulin Therapy, Hyperglycemia, and Hypertension in Type 1 Diabetes Mellitus,” Archives of Internal Medicine, Vol. 168, No. 17, 2008, pp. 1867-1873. http://dx.doi.org/10.1001/archinternmed.2008.2 + +[41] Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group, “Sustained Effect of Intensive Treatment of Type 1 Diabetes Mellitus on Development and Progression of Diabetic Nephropathy: The Epidemiology of Diabetes Interventions and Complications (EDIC) Study,” Journal of the American Medical Association, Vol. 290, No. 16, 2003, pp. 2159-2167. http://dx.doi.org/10.1001/jama.290.16.2159 + +[42] T. M. Davis, I. M. Stratton, C. J. Fox, R. R. Holman and R. C. Turner, “UK Prospective Diabetes Study 22. Effect of Age at Diagnosis on Diabetic Tissue Damage during the First 6 Years of NIDDM,” Diabetes Care, Vol. 40, No. 9, 1997, pp. 1435-1441. http://dx.doi.org/10.2337/diacare.20.9.1435 + +[43] C. C. Cowie and M. I. Harris, “Physical and metabolic characteristics of persons with diabetes,” In: M. I. Harris, Ed., Diabetes in America, 2nd edition, National Diabetes Information Clearinghouse, 1 Information Way, Bethesda, 1995, pp. 117-164. + +[44] J. M. Sprafka, A. P. Bender and H. G. Jagger, “Preva- diff --git a/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_18_pg1_pg1_repeat1.md b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_18_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0f1875a935a93e22b468579cdf2519ee9b76a118 --- /dev/null +++ b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_18_pg1_pg1_repeat1.md @@ -0,0 +1,11 @@ +# The Planning Process—A Summary + +The Waiting List Planning Group initially met on March 25, 1999 in Harrisburg, Pennsylvania. The Work Group learned about the national perspective, including the root causes of waiting lists across the states and brief presentations on the waiting list initiatives in other states. This was followed by a detailed presentation by representatives from Maryland on the Maryland Waiting List Initiative. Finally, the Work Group was oriented to the Pennsylvania Waiting List Study by Temple University and the work to be done in Pennsylvania as addressed in the Multi-Year Plan under the goal of resource realignment to realign existing services to meet the needs of those on the waiting list, as well as recommendations regarding the movement of persons out of State Centers. It was emphasized from the start that the Plan to address the waiting list is both a plan to address the needs of particular people and an effort to establish a system and a process to address the management of the waiting list over time. The second meeting of the Waiting List Work Group was held on May 5-6, 1999, and it represented the first real working session of this group. During the May meeting, the Work Group defined the purpose and the scope of the Plan and developed an outline of the waiting list Plan. Purpose: The purpose of the waiting list planning effort is to develop a plan and a budget to address the needs for services including both persons currently on the waiting list for services and persons not on the waiting list but expected to request services. + +## Scope: The plan will include all persons other than those needing early intervention supports and services. The plan will examine state policies and procedures and their implications at the county level. + +Next, OMR presented initial information on people served and associated costs. Temple University then presented the results of the Temple Waiting List Study. The data indicated that a total of 14,083 persons were waiting for mental retardation services across Pennsylvania, including 411 persons, or 2.9% of the total in the Emergency Needs Group (individual needs services immediately); 3,244 persons, or 23.0% of the total in the Critical Needs Group (individual needs services within one year); and 10,428 persons, or 74.0% of the total in the Planning for Needs Group (individuals’ projected needs are greater than one year away). The study grouped services by category and grouped persons by Low, Medium, or High Intensity Services. One important finding was that an average of 49% of the individuals who came into service during the year under study was not on waiting lists. This began to be commonly referred to as the “shadow waiting list.” In summary, the Temple Waiting List Study revealed that there are 411 persons in Pennsylvania who need services immediately (Emergency Need); and 3,244 persons who need services within the next year (Critical Need). + +Following the presentation of the Temple data, the Work Group began to review and to discuss service and support packages and associated costs. The Work Group identified issues and priorities and began to structure resource groups that could be used to inform the Work Group members and to assist in their deliberations for the next meeting. + +The third meeting of the Waiting List Plan Work Group was scheduled for June 14-15, 1999. The June meeting focused on the capacities of families, providers, counties, and the state to expand services to meet the needs of persons on the waiting list. Numerous issues related to capacity were identified for discussion and review by the Work Group for possible recommendations to be included in the Plan. The Work Group then began to identify priorities for services and supports within broad categories of service; for example, family support services, day supports, residential supports, etc. It was agreed that for the next meeting, members would vote diff --git a/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_21_pg1_pg1_repeat1.md b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_21_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..64b242194f5cf9e63a8585b3c1c3f3509af2f4b6 --- /dev/null +++ b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_21_pg1_pg1_repeat1.md @@ -0,0 +1,43 @@ +## THE PLAN + +## Principles + +Following are the Principles that provide the foundation for the Plan to address the waiting list in Pennsylvania. All decisions and actions related to the provision of mental retardation services and supports are to be weighed against these principles. + +## Everyday Lives + +Everyday Lives, published in 1991, expresses the values upon which the Pennsylvania Mental Retardation Service System is based. Everyday Lives presented what people with disabilities said is important to them. + +Choice - in the decisions of life; choice of jobs, friends, recreation, where and with whom to live. + +Control - of relationships, money, transportation, services, medicine and staff. + +Permanency - with a life in the community among family and friends; no fear of returning to the institution. + +Security - and protection for those who have difficulty in communication; competent services; and safety in the community. + +Freedom - of movement, and from stigma. + +Prosperity - freedom from poverty and a chance to be successful. + +Individuality - by having a name and a personal history and by making a difference; having dignity and status. + +Relationships - with friends, family and partners. + +Recognition - of abilities, capacities and gifts. + +Privacy - of records, files and histories; protection from being labeled and the option of living alone. + +Citizenship - as part of the community, having a feeling of connectedness, partnership in dreams and beliefs; playing a part in decisions which affect you. + +Passion - in advocates and self-advocates to fight and dream together. + +## Multi-Year Plan + +The Multi-Year Plan, published in 1997, builds on the promise of Everyday Lives in terms of goals, recommendations, and action steps. The Multi-Year Plan is a plan for the future which provides a backdrop for recommendations to address the waiting list in Pennsylvania. It included a major goal to realign resources to meet the needs of those on the waiting list. While resource realignment has addressed the need of some people on the waiting list, we have concluded that the realignment of resources alone will not provide sufficient resources to meet the needs of all who are on the waiting list. + +Two major goals: + +System Reform: restructuring the system to one that is: Consumer-Driven, Values-Based, Outcome-Oriented, and Cost-Efficient. + +Resource Realignment: realigning existing resources to meet the needs of those on the waiting list while maintaining necessary supports and services for individuals currently receiving them. diff --git a/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_22_pg1_pg1_repeat1.md b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_22_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..84a2c4db8632e06b790f0edb2d3471c69f8f37b4 --- /dev/null +++ b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_22_pg1_pg1_repeat1.md @@ -0,0 +1,45 @@ +## Recommendations contained in the Multi-Year Plan include: + +1. Restructuring the administration of the program to assure quality, efficiency, and positive individual/family outcomes and satisfaction. + +2. Shifting priorities for resource allocation from facility-based programs to services that build on natural supports. + +3. Creating mechanisms for individuals and families to control resources allocated to meet their need. + +4. Pursuing regulatory reform. + +5. Unifying funding and eliminating categoricals within the mental retardation system. + +6. Reinvesting savings from system reorganization into community services. + +7. Provide services and supports in the community for 1,500 people who are currently living in State ICFs/MR over 5 years. + +8. Transfer state and federal funding for 2,100 persons who live in non-state ICFs/MR into the community funding system by conversion to the Medicaid Waiver. + +# Self Determination + +The principles of self determination hold that all individuals have the right to determine the course of their own lives. All individuals need to be free to exercise this right and to accept responsibility for their decisions. It is recognized, however, that some individuals require a greater degree of support in doing this than others. Family members and friends provide support and have a role in helping + +individuals determine and achieve their life goals. In this process, government plays a supportive role as necessary. + +## Self determination means: + +...freedom to decide + +...support and information to make decisions + +...control over resources + +and...responsibility for decisions and actions. + +# Quality Services and Supports + +Quality is a fundamental consideration in the provision of services and supports. People receiving services and their families deserve the highest quality and they must be assured that quality is continually measured by people who are knowledgeable, trained and independent. + +## Quality means: + +Maintaining health and safety... + +Achieving optimal service outcomes for people... + +Providing to consumers and families value for the dollar. diff --git a/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_29_pg1_pg1_repeat1.md b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_29_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..05e1b7351c3fc747465e6aeaf12bb089985c30cd --- /dev/null +++ b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_29_pg1_pg1_repeat1.md @@ -0,0 +1,51 @@ +## Categories of Need + +Persons needing services immediately. + +Emergency + +Persons needing services within one year. + +Critical + +Persons with needs more than one year away. + +Planning For + +## Categories of Service + +High Intensity + +Persons receiving residential services, possibly in addition to vocational/day services, ancillary/support services, and case management + +Medium Intensity Persons receiving vocational/day services, possibly in addition to support/ancillary services and case management + +Low Intensity + +Persons receiving support or ancillary services (therapies, F.S.S., transportation), in addition to case management services + +## Types of Service + +Day Services + +Non-residential services to people with mental retardation including adult developmentaltraining, vocational rehabilitation, and community employment + +Residential Services Services necessary to maintain a person in (24 hour staff) setting by providing staffing support 24 hours a day. + +their home or in some other residential + +Residential Services (Not including 24 hour staff) + +## Fiscal Year + +## Infrastructure + +## PUNS + +Services to people who require some degree of staffing support to maintain them in their home, but do not require staffing on a 24 hour/day continuous basis. + +The 12 month period from July 1 to June 30 on which Commonwealth budgets are based. + +The basic foundation that must be in place for an organization to function properly (administrative, information systems, staffing). + +Prioritization of Urgency of Need for Services for Persons with Mental Retardation—Data collection instrument developed by Temple University to assess the need of individuals waiting for services. diff --git a/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..bff341ed523365b70223049c1552196f4ad59cf6 --- /dev/null +++ b/outputs/multi_column/028649690bbc67fe3ba040b4b2bf6c37f487_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +# Addressing Pennsylvania’s Waiting List + +Pennsylvania, like most other states, has waiting lists for mental retardation services. In recent years, it was estimated that approximately 22,000 to 28,000 persons were on such waiting lists in counties across Pennsylvania. + +Initiatives begun from Fiscal Year 1996-97 through Fiscal Year 1999-2000 will expand services to more than 3,000 persons and will result in an annualized amount of approximately \$134.1 million to reduce Pennsylvania’s waiting list for mental retardation services. This has included expanded funding through the Home and Community-Based Waiver, increased in-home and family support services, and expanded out-of-home residential services. + +However, without a standard definition of the waiting list, and county MH/MR programs following different processes in maintaining waiting lists, it was difficult to measure the scope of need and the impact of expanded services. + +In an effort to further study this phenomenon and to enable the Department of Public Welfare to initiate strategic planning to address the waiting list across the state, during Fiscal Year 1996-97, the Office of Mental Retardation commissioned a study of the waiting list for services in Pennsylvania by the Institute on Disabilities/University Affiliated Program (IOD/UAP) of Temple University in Philadelphia. Phase I of the study involved documentation of how large the waiting list is, as well as what services are being requested. Also, the study gathered information to document how counties across the state report, track, and control their waiting list data. + +Several major issues were raised. It became clear that counties did not employ a uniform procedure to capture waiting list data in support of annual county plans. Individual counties varied widely in their reporting. There was a lack of a clear definition of the waiting list. As a result, it was recommended that the Office of Mental Retardation develop consistent definitions and data collection methods for determining the size of the waiting list and the characteristics of persons on the waiting list. Counties also reported using various methods of tracking and controlling their waiting lists. The study identified five main methods used by counties. In order to develop a consistent definition of the waiting list and to develop a uniform data collection and tracking procedure for the waiting list, Temple University worked with a subcommittee to develop a data collection instrument entitled, “Prioritization of Urgency of Need for Services for Persons with Mental Retardation (PUNS).” Following a pilot test, phase II of the study began with a statewide distribution of the PUNS form to be completed by each of the 45 county MH/MR programs on each individual designated by the county to be waiting for service. By April 1999, data was received from each county program on each person identified on a waiting list. Data was then analyzed by Temple University regarding three broad categories used to classify need: Emergency (persons needing services immediately); Critical (persons needing services within one year); and Planning For (persons with needs greater than one year away). Services were grouped according to four major categories as case management only; other ancillary and support services; vocational and other adult day services; and residential services. Individuals were grouped by low, medium, and high intensity services and categorized in terms of services being asked for; needed; currently receiving; and in need of more. + +In May 1999, results of the survey revealed that a total of 14,083 persons were on waiting lists for services in Pennsylvania. Of these diff --git a/outputs/multi_column/028b869f7c53f2698a66f1bc92c5dea0f2f8_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/028b869f7c53f2698a66f1bc92c5dea0f2f8_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d62fcb1a677c2779b9512d753e6b67490f38b4fd --- /dev/null +++ b/outputs/multi_column/028b869f7c53f2698a66f1bc92c5dea0f2f8_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,67 @@ +Kokse und Kohlen + +KBK + +Feinkalk + +Feinkoks + +Söderbergmasse + +![](figure) + +Abb. 4 Hauptströme beim Carbidprozess + +120 + +100 + +80 + +60 + +40 + +20 + +2005 + +2006 + +2007 + +2003 + +2004 ● Importkohle frei deutsche Grenze + +Filterstaub (UVO-Staub) + +Wasserkondensat + +Ölkondensat + +Teerkondensat + +Carbid + +2008 + +2009 + +2010 + +## 2 Per. Gleitender Durchschnitt (Importkohle frei Grenze) + +![](figure) + +Abb. 5 Preise von Importkohle von 2003 bis 2010 (Zusammenstellung AlzChem GmbH) + +In der Mitte des Ofens tauchen Elektroden in den Möller, an deren Spitzen der Schmelzprozess stattfindet. Ein hoher Stromfluss zwischen den Elektroden erwärmt das Gemisch, bis es zu einer chemischen Reaktion zum Calciumcarbid kommt. Als Koppelprodukt entsteht Carbidofengas mit den Hauptbestandteilen Kohlenmonoxid und Wasserstoff. Seit Jahrzehnten hat sich eine spezielle Bauweise der Elektroden in Form von Hohlelektroden bewährt. Durch sie hindurch wird feinkörniger Möller direkt zu den Elektrodenspitzen eingebracht, wo dieser unmittelbar zu Calciumcarbid umgesetzt wird. Dies bietet enorme Vorteile für die Prozessführung. Aus Abstichlöchern, die sich am Boden der Ofenwanne befinden, fließt das schmelzflüssige Calciumcarbid in Carbidpfannen und erstarrt in diesen zu einem Block. Nach einer Abkühlzeit von ca. 30 Stunden wird der entstandene Block vorgebrochen. Danach wird durch Sieben, Nachbrechen und Mahlen die gewünschte Körnung hergestellt. Bis zu diesem Zeitpunkt ist viel Energie eingesetzt worden. Um die Reaktionstemperatur zu erzeugen, die in der Hauptreaktionszone über 2.000 °C beträgt, fließen zwischen den Elektroden Ströme von bis zu 140.000 Ampere. Ca. 3.200 bis 3.500 kWh werden benötigt, um aus etwa 1.000 kg Kalk und rund 600 kg Schwarzstoffe eine Tonne Carbid herzustellen. + +# Calcium bindet Chlor + +Kunststoffabfälle wurden bisher noch nicht in Elektroniederschachtöfen eingesetzt. Für das neue Verfahren waren daher zahlreiche Fragen zu klären: Wie verändert sich die Produktqualität, welche Änderungen sind bei den Emissionen zu erwarten, insbesondere, wenn chlorhaltige Materialien umgesetzt werden? Im Labormaßstab ließen sich diese Fragen nicht beantworten, die Experten mussten ihre Betriebsversuche auf Produktionsebene durchführen. Nach Umbauten an einem der beiden Carbidöfen des Unternehmens starteten die Versuche mit einer sukzessiven Erhöhung der beigemischten Kunststoffmengen. Dabei wurden alle Stoffströme und Emissionen genau erfasst. Ein besonderes Augenmerk galt den chlorhaltigen Stoffen, die in Verbrennungsprozessen giftige Dioxinverbindungen bilden können. Durch gezielte Zugaben von Polyvinylchlorid (PVC) steigerten die Spezialisten den Chloranteil im Kunststoff in mehreren Schritten auf bis zu 12%. Es waren keine spürbaren Auswirkungen auf den Carbidprozess, das Endprodukt und die Emissionen zu verzeichnen. Wie erwartet, wird das Chlor überwiegend im Staub des Ofengases als Calciumchlorid gebunden. Daher ist im Abgas des Elektroniederschachtofens keine ● Steigerung der Dioxinwerte messbar. Auch die Schwermetallanteile sind weitgehend in diesem Staub gebunden, den eine Filteranlage abtrennt. Somit sind die Schwermetalle in einem vergleichsweise kleinen Mengenstrom des Verfahrens konzentriert und können entsorgt werden. Aufgrund der positiven Ergebnisse sicherte sich das Unternehmen die Patentrechte in wirtschaftlich bedeutenden Staaten und beantragte eine Genehmigung nach dem Bundes-Immissionsschutzgesetz, die am 23.06.2010 erteilt wurde. + +# Ofengas wird noch wertvoller + +Die chemische Reaktion, die der Carbidproduktion zu Grunde liegt, setzt ein Drittel des beteiligten Kohlenstoffs in Kohlenmonoxid um. Dieses Koppelprodukt ist keineswegs Abfall. Es wird als wertvoller Ausgangsstoff für chemische Prozesse und als Brennstoff genutzt. Durch den Zusatz von Kunststoffen im Möller ändern sich sowohl die Menge als auch die Zusammensetzung des Ofengases. Neben dem Kohlenmonoxid und Wasserstoff enthält es jetzt auch höhere Anteile Methan und andere Kohlenwasserstoffe. „Es entsteht mehr und qualitativ hochwertigeres Carbidofengas als bisher“, erläutert Jürgen Franke. „Während die Gasmenge um 30% zunimmt, verbessert sich gleichzeitig der Heizwert um etwa 20%.“ Das Ofengas wird aufwendig gereinigt, verdichtet und an den Standorten des Unternehmens so-wie an weitere externe Kunden geleitet. Dort dient es als Synthese- und Heizgas für die stoffliche und thermische Anwendung. Um das Ofengas noch effizienter zu nutzen, wird geprüft, ob der Einsatz von Gasmotoren technisch machbar ist. In umfänglichen Versuchsreihen passen die Ingenieure gemeinsam mit Industriepartnern die Technik solcher Motoren an die Eigenschaften des Ofengases an. diff --git a/outputs/multi_column/028b869f7c53f2698a66f1bc92c5dea0f2f8_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/028b869f7c53f2698a66f1bc92c5dea0f2f8_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..bda58dcb769dd301c664fe8941e3f68eef7e0f05 --- /dev/null +++ b/outputs/multi_column/028b869f7c53f2698a66f1bc92c5dea0f2f8_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,65 @@ +![](figure) + +# Stoffliche Verwertung soll steigen + +„Der Markt für Kohle und Koks hat sich in den vergangenen Jahren drastisch verändert“, so die Beobachtung von Dr. Klaus Holzrichter, dem Standortleiter der AlzChem in Trostberg. Ehemalige Kohle-Exportländer wie China und Indien haben sich zu Importeuren gewandelt. Die Kohlepreise auf dem Weltmarkt steigen unablässig. Mit der Substitution von Kohle durch Kunststoffe, um den darin enthaltenen Kohlenstoff nicht nur energetisch, sondern stofflich für neue Produkte zu verwerten, hat die AlzChem jetzt weltweit ein Alleinstellungsmerkmal. Die abfallpolitische Einordnung wurde von Herrn Dr. h. c. Karl J. Thomé-Kozmiensky auf der Berliner Energiekonferenz 2011 wie folgt beschrieben: „Auch aus umweltpolitischer Sicht ist es vorteilhaft, dass der im Kunststoff enthaltene Kohlenstoff nicht energetisch sondern rohstofflich verwertet wird. Damit ist das Verfahren in der Prioritätenfolge der Abfallrahmenrichtlinie höher einzuordnen als die Verbrennung der Altkunststoffe als Ersatzbrennstoffe.“ In einem neuen Projekt will das Unternehmen auch für das in PVC enthaltene Chlor eine stoffliche Verwertung ermöglichen. „Um dieses Ziel zu erreichen, nutzen wir eine altbekannte Eigenschaft von PVC, nämlich bei Temperaturen oberhalb von ca. 250 °C Chlorwasserstoff abzuspalten“, erläutert Dr. Hans-Hermann Niemeyer, der das Projekt leitet. „Parallel dazu erhält man einen kohlenstoffreichen „PVC-Koks“, der dann die konventionellen Schwarzstoffe für die Carbid-Herstellung in Zukunft teilweise ersetzen soll.“ Der „PVC-Koks“ soll natürlich im Carbid-Verfahren auf Herz und Nieren getestet werden. Dazu wird ein Versuchsofen gebaut, der sogenannte Technikums-Carbid-Ofen. + +# Projektbeteiligte + +#### >> Projektadressen: + +AlzChem Trostberg GmbH, Trostberg Stoffstrommanagement: Jürgen Franke, juergen.franke@alzchem.com Betriebsleiter: Josef Oberbauer, josef.oberbauer@alzchem.com + +# Links und Literatur + +## >> www.alzchem.de/de + +>> Franke, J.; Saller, E.: F&E-Projekt: Energieeffizienter Betrieb eines Carbid- Niederschachtofens mittels Pyrolyse (Ofengasverstromung). Abschlussbericht. AlzChem Trostberg GmbH, Trostberg (Hrsg.). 2010. 47 S., FKZ 0327409A. Signatur TIB Hannover: F 10 B 2967 (als pdf zum download unter http://opac.tib.uni-hannover.de/DB=1/LNG=DU/) + +# Mehr vom BINE Informationsdienst + +>> Dieses Projektinfo gibt es auch online und in englischer Sprache unter www.bine.info im Bereich Publikationen/Projektinfos. In der Rubrik „Service“ finden Sie ergänzende Informationen wie weitere Projektadressen und Links. + +>> BINE Informationsdienst berichtet aus Projekten der Energieforschung in seinen Broschürenreihen und dem Newsletter. Diese erhalten Sie im kostenlosen Abonnement unter www.bine.info/abo + +# Projektorganisation + +Bundesministerium für Wirtschaft und Technologie (BMWi) 11019 Berlin Projektträger Jülich Forschungszentrum Jülich GmbH Dr. Michael Gahr 52425 Jülich Förderkennzeichen 0327409A + +# Impressum + +## ISSN + +0937 - 8367 + +## Herausgeber + +FIZ Karlsruhe GmbH · Leibniz-Institut für Informationsinfrastruktur Hermann-von-Helmholtz-Platz 1 76344 Eggenstein-Leopoldshafen + +## Autor + +Dr. Franz Meyer + +## Titelbild + +AlzChem Trostberg GmbH + +## Urheberrecht + +Eine Verwendung von Text und Abbildungen aus dieser Publikation ist nur mit Zustimmung der BINE-Redaktion gestattet. Sprechen Sie uns an. + +# Kontakt · Info + +Fragen zu diesem Projektinfo? Wir helfen Ihnen weiter: + +# 0228 92379-44 + +#### BINE Informationsdienst + +Energieforschung für die Praxis Ein Service von FIZ Karlsruhe + +Kaiserstraße 185-197 53113 Bonn + +Tel. 0228 92379-0 Fax 0228 92379-29 kontakt@bine.info www.bine.info + +● diff --git a/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_13_pg1_pg1_repeat1.md b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_13_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3b1706163391fb00fc3c518cc615ebcff3d0bc2c --- /dev/null +++ b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_13_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +votar el articulado del proyecto, que terminaron inviabilizando la estatización de la industria de pensiones y, a la larga, el control del mercado de capitales en Chile. + +Según lo votado, el Estado no tendría participación alguna en la administración e inversión de las pensiones. Todo apunta a que este escenario es muy difícil de revertir en el Senado, ya que los artículos referidos a los antes mencionado contó con los votos en bloque de la oposición y de Demócratas, que, en conjunto, pueden bloquear la iniciativa. “La Cámara de Diputados dio una clara señal al rechazar aspectos estructurales de la reforma previsional”, señaló Paulina Yazigi presidenta de la Asociación de AFP. + +A continuación 3 artículos que fueron rechazados en la Cámara que inviabilizan el control del Estado de la industria. + +1. Fondo Integrado de Pensiones (FIP): La Cámara + +aprobó la creación de un Seguro Social Previsional, el que según establece el mismo proyecto, “será financiado con la cotización de cargo de los empleadores que se señala en el artículo siguiente la cual será enterada en el Fondo Integrado de Pensiones”. Finalmente, solo se aprobó el nombre del fondo, que estaría compuesto con el 3% extra de cotización. Todos los artículos posteriores que hacían relación con el Fondo Integrado de Pensiones fueron rechazados, por lo que en el proyecto queda su sola mención. + +2. Administrador Previsional: El gobierno se jugó + +porque la industria de las AFP dividiese sus roles de administración e inversión de los fondos. En el caso de las administradoras de fondos siempre se apostó porque fuera solo uno y licitado por el Estado. “El servicio de administración de cuentas y beneficios será adjudicado mediante una licitación pública. La licitación y la adjudicación del servicio se regirán por las normas establecidas en + +la presente ley y las respectivas Bases de Licitación que los Ministerios del Trabajo y Previsión Social y de Hacienda aprueben mediante Decreto Supremo para cada contrato en particular”, dice el proyecto. Este administrador estaría a cargo del servicio de atención a afiliados, recaudación de cotizaciones, cartolas, pagos de pensiones y cobranzas. La norma, sin embargo, fue rechazada. + +3. Inversor Previsional: Para el Gobierno era + +especialmente importante que existan inversores privados y uno estatal de los fondos, llamado Inversor de Pensiones Estatales (IPE). La idea era que las personas eligieran entre los gestores privados y el público, aunque con los años era muy probable que los IPE Estatales tomaran el control de la gestión de inversiones y del mercado de capitales y de crédito del país, de acuerdo a la opinión de diversos actores y parlamentarios que se han involucrado en el tema. Se propuso que el IPE tuviera un directorio integrado por 5 personas: Un director nombrado por el Presidente de la República, quien sería el presidente del directorio, y cuatro directores “nombrados por el Presidente de la República, a partir de una terna o cuaterna propuesta para cada cargo por el Consejo de Alta Dirección Pública, con el voto favorable de cuatro quintos de sus miembros”. La iniciativa también fue rechazada. + +Los diputados aprobaron un autopréstamo que no podrá exceder las 30 UF (\$1 millón 100 mil), además del aumento de la Pensión Garantizada Universal (PGU) a \$250 mil y su financiamiento. También se aprobó el artículo 82 que del título III del decreto 3.500, en el que se cambia el nombre de “Administradoras de Fondos de Pensiones” (AFP) por “Administrador Previsional”, entre otras cosas. Ahora la discusión se situará en la comisión de Trabajo del Senado, que a partir de marzo será liderada por Iván Moreira (UDI). diff --git a/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_16_pg1_pg1_repeat1.md b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_16_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6d240ce98d4fa59e247d988fdeb5b2c3f4c0a66d --- /dev/null +++ b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_16_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +reforma del 2020, que incrementa de manera gradual las aportaciones patronales para llegar a una tasa de 15% en el 2030, el Presidente dijo que el gobierno asumirá parte de las aportaciones. En este sentido, el presidente de la Amafore indicó que el presidente del país dio certidumbre respecto a las administradoras de fondos y el ahorro que ya existe en ellas, lo cual es una condición muy importante, porque eso le da certeza a los trabajadores de que su cuenta individual, y en consecuencia su ahorro, no será utilizado (contrario a lo que algunas personas han empezado a rumorar). Ningún país, incluso de los avanzados, tiene una tasa de reemplazo de 100%, es decir, que los trabajadores al retirarse reciban por completo el último salario que percibieron, por lo que expertos en el tema ven difícil que esto se pueda lograr. En ese sentido, los expertos han señalado que una aportación del gobierno podría apretar y reducir aún más el espacio fiscal, por lo que sería necesario una reforma fiscal o mayores medidas de austeridad. www.eleconomista.com.mx; Fecha: Enero 2024). + +(Fuente: + +# Perú + +AFPs reducen tasa de seguro de invalidez, sobrevivencia y gastos de sepelio, desde 1,84% a 1,70% a contar de enero 2024. Los afiliados al Sistema Privado de Pensiones (SPP) pagarán 1,70% por la tasa del seguro previsional a partir de 2024. Así lo anunció la Asociación de AFP al cierre de la sétima licitación de los seguros de invalidez, sobrevivencia y sepelio bajo póliza colectiva (Sisco VII). “La tasa actual de 1,84% baja a 1,70%. Con esta tasa menor reafirmamos nuestro compromiso de trabajar en beneficio de los afiliados”, sostuvo Giovanna Prialé, presidenta de la Asociación de AFP. En la licitación, las seis compañías de seguros participantes presentaron + +[^2]: El sistema de pensiones de vejez de los Emiratos Árabes Unidos consiste en el programa de seguro social (reparto) administrado por la GPSSA y una pensión social sujeta a verificación de recursos (Abu Dhabi gestiona programas de seguro social separados para todos los empleados locales y Sharjah para los empleados del sector público local). Para + +sus ofertas para obtener al menos una de las siete fracciones que representan a los afiliados al SPP. En total, cuatro aseguradoras cubrieron las siete fracciones licitadas. Finalmente, como resultado del Sisco VII, se estableció una prima de 1,70%, que se aplicará del 1 de enero al 31 de diciembre de 2024. La tasa del seguro previsional es recaudada por las AFP mensualmente y transferida directamente a las aseguradoras. En el SPP, el seguro de invalidez, sobrevivencia y gastos de sepelio protege al afiliado y a sus beneficiarios ante el riesgo de invalidez (disminución de la capacidad para trabajar por enfermedad o accidente) o de fallecimiento. (Fuente: https://larepublica.pe; Fecha: 29.09.2023). + +Asociación de AFP: “Los retiros que se vienen discutiendo en el Congreso son una antirreforma”. La presidenta de la Asociación de AFP, Giovanna Prialé, en entrevista, abordó la propuesta de reforma del Ejecutivo, proponiendo medidas innovadoras para asegurar acceso universal y una pensión mínima. Aseveró además que los retiros discutidos en el Congreso van en contra de la posibilidad de construir pensiones en nuestro país, y es crucial trabajar de manera ordenada y responsable. (Fuente: https://peru21.pe; Fecha: 06.12.2023). + +# Asia y el Pacífico + +# Emiratos Árabes Unidos + +El país reforma su programa de seguro social de reparto, que, entre otros aspectos, aumenta las contribuciones y la edad legal de jubilación. El 17 de noviembre de 2023, la Autoridad General de Pensiones y Seguridad Social (GPSSA) de los Emiratos Árabes Unidos (EAU) anunció una nueva ley que reforma el programa federal de pensiones del seguro social del país[^2] que cubre a la mayoría + +tener derecho a una pensión de vejez del seguro social, un emiratí debe haber alcanzado la edad normal de jubilación de 60 años y tener al menos 15 años de aportes. Aunque el programa de seguro social no cubre a los empleados no emiratíes, que constituyen la mayor parte de la fuerza laboral del sector privado del país, estos empleados pueden calificar diff --git a/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_21_pg1_pg1_repeat1.md b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_21_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..69aad3e33f81a5c3572edec84753ff3b61cf322e --- /dev/null +++ b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_21_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +la edad normal de jubilación para las mujeres, altera las reducciones de la edad de jubilación para las madres, ralentiza los aumentos de contribución de las mujeres para obtener una pensión completa, cambia la elegibilidad para la jubilación anticipada, modifica la fórmula de beneficios de pensión de vejez, e implementa ajustes en las pensiones por el costo de vida. Las reformas están destinadas a mejorar la adecuación y sostenibilidad del programa de seguro social del país y son una condición para recibir asistencia financiera adicional del fondo de recuperación pandémica de la Unión Europea. Según la Casa Nacional de Pensiones Públicas, que administra el programa de seguro social, en noviembre había 4,6 millones de pensionistas que recibían una pensión mensual promedio de 2.009 lei (USD 439). Las reformas clave realizadas por la nueva ley (todas efectivas a partir del 1 de enero de 2024, a menos que se indique lo contrario) incluyen: + +(i) Aumento de la edad normal de jubilación para las mujeres: La edad normal de jubilación para las mujeres aumentará gradualmente de 62 años y 1 mes a 65 años (la misma edad normal de jubilación para los hombres) hacia enero de 2035. Según las normas actuales, la edad normal de jubilación para las mujeres aumentaría gradualmente hasta 63 en enero de 2030. + +(ii) Modificación de las reducciones en la edad de jubilación para las madres: Según la nueva ley, las mujeres que tienen un período de cotización completo (actualmente 32 años y 4 meses de cotizaciones) pueden recibir una reducción de 6 meses en su edad normal de jubilación por cada hijo que críen hasta los 16 años, con una reducción máxima de 3 años y 6 meses. Actualmente, las mujeres que + +ciertas ocupaciones arduas o difíciles. El programa de cuenta individual se financia con contribuciones de los empleados del 3,75% de los ingresos cubiertos. + +hayan cumplido el período mínimo de cotización de 15 años pueden recibir una reducción de 6 años por criar a tres hijos hasta los 16 años más una reducción de 1 año por cada hijo adicional criado. + +(iii) Aumentos más lentos en el período de cotización completo de las mujeres: El período de cotización requerido para que las mujeres reciban una pensión de vejez completa aumentará gradualmente de 32 años y 4 meses a 35 años (el mismo período de cotización completo para los hombres) hacia enero de 2035 en lugar de enero de 2030. El período mínimo de cotización para una pensión de vejez (pensión parcial) se mantendrá en 15 años tanto para mujeres como para hombres. + +(iv) Cambio de elegibilidad para la jubilación anticipada: Las personas aseguradas pueden reclamar pensiones de vejez completas hasta 5 años antes de la edad normal de jubilación si sus años de cotizaciones exceden el número requerido para una pensión completa en al menos 5 años en lugar de 8 años. Los asegurados seguirán teniendo la posibilidad de reclamar pensiones de vejez parciales hasta 5 años antes de la edad normal de jubilación si han completado los períodos de cotización completos. + +(v) + +Modificación de la fórmula de las prestaciones de las pensiones de vejez: en septiembre de 2024 se introducirá una nueva fórmula de prestaciones para garantizar que los trabajadores en los mismos puestos de trabajo durante el mismo número de años reciban pensiones de vejez iguales. Los beneficios que reciben los actuales pensionados se recalcularán mediante esta nueva fórmula, que seguirá basándose en un diff --git a/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4a76431d06548351d3bd7457e250bbc7d190fbe3 --- /dev/null +++ b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,37 @@ +# Informes o presentaciones relevantes + +Este informe, + +El Foro Económico Mundial (WEF) publica informe sobre los principios de la economía de la longevidad para lograr un futuro financieramente resiliente. desarrollado por un consorcio de líderes de finanzas, salud, academia y gobierno, ofrece un enfoque estratégico a los desafíos y oportunidades de una población global que envejece. Propone principios destinados a garantizar la resiliencia financiera de todas las generaciones en medio de diversos sistemas nacionales y objetivos como la seguridad financiera y una vida saludable. Para 2050, se prevé que la población mundial mayor de 60 años se duplique, pasando de 1.000 millones en 2020 a 2.100 millones, lo que subraya la urgente necesidad de adoptar enfoques estratégicos para abordar el envejecimiento. El informe aborda cuestiones delicadas como la discriminación por edad, las brechas de género en las pensiones y las disparidades socioeconómicas en los ahorros para la jubilación. El informe también aboga por un enfoque holístico que equilibre la salud, la estabilidad financiera y las consideraciones sociales, y subraya la importancia de la participación colaborativa de múltiples partes interesadas centrada en las necesidades individuales. El objetivo es construir soluciones sostenibles y resilientes para la demografía mundial que envejece rápidamente. Los autores proponen seis principios para la economía de la longevidad, que buscan garantizar la resiliencia financiera de todas las generaciones: + +(i) + +Asegurar la resiliencia financiera ante eventos clave de la vida. + +(ii) + +Acceso universal a la educación financiera. + +(iii) + +Priorizar el envejecimiento saludable como fundamento para la economía de la longevidad. + +(iv) + +Adaptar empleos y desarrollar habilidades para una fuerza laboral multigeneracional. + +(v) + +Diseñar sistemas y entornos para la conexión social. + +(vi) + +Abordar las desigualdades de longevidad. + +Estos principios ofrecen una visión ambiciosa para una economía de la longevidad equitativa y sostenible. Su implementación requerirá un esfuerzo concertado de gobiernos, empresas y sociedad civil. Sin embargo, el potencial de estos principios para mejorar la vida de las personas de todas las edades es considerable. (Fuente: https://www.weforum.org/; Fecha: 15.01.2024). + +La OCDE publica estudio sobre el círculo vicioso del empleo informal y el trabajo mal remunerado. perspectivas sobre la informalidad. En primer lugar, explica la mecánica de los vínculos nocivos entre el empleo informal, el trabajo mal remunerado y las bajas calificaciones/habilidades. De acuerdo con el trabajo: + +El documento añade dos + +(i) La mayoría de los trabajadores de las economías en desarrollo y emergentes soportan una doble carga de empleo informal y trabajo mal remunerado. Los trabajadores informales representan casi el 60% de la fuerza laboral a nivel mundial y el 90% en los países de bajos ingresos. A pesar de la heterogeneidad generalizada, la informalidad suele mostrar una estructura de dos niveles. El nivel inferior comprende a los trabajadores con ingresos inferiores al 50% de los ingresos medios de su país: son la mayoría de la fuerza laboral informal mundial, un 54% en promedio, y hasta un 80% en algunos países. Un número relativamente pequeño de trabajadores en el nivel superior disfruta de ingresos relativamente más altos; también son más cualificados y más productivos. En diff --git a/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e96b486c77452432d8ad6384415663ab3f0cce2f --- /dev/null +++ b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +positivamente a las políticas de formalización estándar, se deben considerar medidas adicionales, como garantizar una cobertura adecuada de las leyes laborales, la seguridad social y las regulaciones tributarias, así como hacer cumplir estas regulaciones por parte de los trabajadores y empleadores. (Fuente: https://www.oecd-ilibrary.org; Fecha: 15.01.2024). + +Universidad de los Andes propone en un estudio tres modificaciones al proyecto de reforma de pensiones del gobierno colombiano, con el fin de hacerlo más fiscalmente razonable, y reducir los efectos en el mercado de capitales. Aunque Universidad de los Andes - Colombia ve como una necesidad el cambio al sistema de pensiones del país, calificándolo como “excluyente, regresivo e ineficiente”, en una nota propone cambios para la reforma que se discute + +1. Bajar el umbral de salarios mínimos por los que hay que contribuir al esquema de reparto manejado por Colpensiones (1,5 salarios mínimos, en lugar de los 3 que propone el gobierno). Un umbral más bajo permitiría: (i) que el Estado garantice niveles de ingreso básico para los pensionados, dejando en manos del ahorro individual—no de los subsidios—los complementos a los ingresos del pilar de reparto para las personas de mayores ingresos; y (ii) suavizar el costo fiscal entre generaciones. + +2. Aumentar la edad mínima de pensión en tres años para hombres y mujeres (hombres pasarían de 62 a 65; y mujeres de 57 a 60). Ello, ya que a medida que la esperanza de vida aumenta, también lo hacen los años de disfrute de la pensión. Los sistemas solo serán financieramente sostenibles si balancean los años de contribución con los de disfrute de la pensión. + +3. Mantener las semanas de cotización de las mujeres en 1300. El proyecto de Ley establece + +un bono en semanas por cada hijo para sus respectivas madres. Si se agrega ese bono, proponen mantener las semanas de cotización de las mujeres en 1300, al mismo nivel de las de los hombres. El sistema les otorgaría a las mujeres una menor edad de jubilación relativa a la de los hombres y el bono de semanas por cada hijo. + +Esos tres cambios tendrían importantes avances en la sostenibilidad fiscal y haría al sistema más equitativo entre generaciones. Comparado a un escenario sin reforma, la combinación de las medidas propuestas genera un esfuerzo fiscal adicional del 12% del PIB, es decir 45% del PIB menos que la reforma discutida. (Fuente: https://economia.uniandes.edu.co/; Fecha: Diciembre 2023). + +Informan que en Estados Unidos, los programas estatales de enrolamiento automático en planes IRA (conocidos como Auto IRA) llegaron a los USD 1.100 millones en activos bajo administración al 30 de noviembre de 2023, con más de 800 mil cuentas y casi 200 mil empleadores. De esta forma, el país tiene claro que la respuesta adecuada para enfrentar las tendencias demográficas en materia de pensiones, es incrementar el ahorro individual, usando las herramientas de la economía conductual. Por esta razón, a la fecha casi una veintena de estados han promulgado nuevos programas de pensiones para trabajadores del sector privado y/o público, la mayoría de cuales son Auto IRA. En estos planes se deducen automáticamente 3% (Connecticut) o 5% (California, Illinois y Oregon) del salario del trabajador (éste tiene opción de salirse del plan). En Oregon e Illinois las cotizaciones escalan 1 punto porcentual del salario al año hasta llegar a 10% y en California hasta llegar a 8%. (Fuente: https://www.massenaassociates.com/; 14.12.2023). + +Fecha: diff --git a/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e8e3adcc43c799e5e702af3bbf38a7dfcfdcfbd7 --- /dev/null +++ b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +las mujeres que comienzan su carrera hoy. En Dinamarca, Estonia, Italia, los Países Bajos y Suecia, la edad normal de jubilación aumentará a 70 años o más si se materializan aumentos en la esperanza de vida a medida que se aplican los vínculos proyectados y legislados con la esperanza de vida. + +La participación de los trabajadores mayores en la fuerza laboral ha aumentado drásticamente en toda la OCDE, y la tasa de empleo de las personas de 55 a 64 años en la OCDE alcanzó un récord del 64% en el segundo trimestre de 2023, casi 8 puntos porcentuales más que hace una década. Sin embargo, muchos trabajadores de mayor edad todavía luchan por mantener sus habilidades actualizadas, tienen un acceso limitado a empleos de buena calidad y corren el riesgo de recibir una pensión inadecuada en la vejez debido a carreras laborales cortas e inestables. + +Respecto de las tasas de reemplazo, el documento señala que, para un asalariado promedio, la tasa de reemplazo neta en los países de la OCDE es de un 61,4% promedio, en el caso de los hombres, y 60,6%, en el caso de las mujeres. + +Esta edición del informe de la OCDE evalúa el impacto de las políticas de pensiones especiales en los países de la OCDE para trabajadores con trabajos peligrosos y arduos, incluidas aquellas que otorgan acceso a la jubilación anticipada a través de planes de ocupación específicos o reglas especiales dentro de un plan de pensiones general. La prevención de problemas de salud y la recapacitación para sacar a los trabajadores de trabajos arduos antes de que la salud se deteriore significativamente es clave. El apoyo a las personas con problemas de salud relacionados con el trabajo debería proporcionarse principalmente a través de seguros de accidentes, enfermedades e invalidez en el trabajo, en lugar de planes especiales de pensiones de vejez para trabajos peligrosos o arduos. También sería útil mejorar la regulación del tiempo de trabajo y la seguridad en el lugar de trabajo y reforzar el papel de los órganos de inspección del trabajo y los servicios de salud en el trabajo. + +En la siguiente infografía se observan algunos mensajes clave del informe: + +![](figure) + +![](figure) + +(Fuente: OCDE; Fecha: Diciembre 2023). + +Observatorio Perspectivas publicó informe donde se analiza exhaustivamente el sistema de pensiones de Suecia, recogiendo lecciones sobre el retroceso del reparto en un esquema mixto. Aunque Suecia es reconocido por su sistema mixto de pensiones, el peso relativo del pilar de reparto en el mismo ha ido disminuyendo. El modelo nórdico se ubica en el 'top ten' del ranking que elabora la consultora Mercer, en el puesto diff --git a/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d89614c3cf972594f1b4a041cd98916f97d8e149 --- /dev/null +++ b/outputs/multi_column/02943986dff2d4a84b7c2dd81abfc51fceea_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +componentes financiados con ahorro, aunque el aporte mensual es solo 31% del total. Con esta tendencia en los retornos y los cambios regulatorios que equilibran las cuentas nocionales, se proyecta que el peso relativo del ahorro individual en la construcción de las pensiones aumente desde 11,1% a 38,5% en los próximos 40 años, mientras las pensiones ocupacionales crezcan 16,6% a 21%. + +Así, una de las conclusiones del informe apunta a que, para el caso chileno, reincorporar este pilar (de reparto) con resultados inferiores, una vez que se financió todo el costo de la transición, parece ilógico. Los esfuerzos se deberían concentrar en mantener elevados los retornos y contenidos los riesgos a través de un régimen de inversión flexible y moderno. En Suecia se hizo todo lo contrario a lo que se está buscando en Chile hoy, pues pasaron de tener un sistema 100% de reparto a incorporar un pilar de ahorro individual, idéntico al chileno. En tanto, en Chile se está nadando contra la corriente, queriendo incorporar un pilar de reparto a un sistema de ahorro. (Fuente: https://observatorioperspectivas.cl/; Fecha: 11.01.2024). + +Estudio de David Bravo concluye que las tasas de reemplazo de actuales pensionados en Chile son similares a las de la OCDE. Durante el seminario “Pensiones, un necesario rediagnóstico”, organizado por la Asociación de AFP, el economista David Bravo, director del Centro UC de Encuestas y Estudios Longitudinales, presentó un inédito estudio sobre el sistema previsional de Chile, en que ponderó el impacto en las pensiones de la Pensión Garantizada Universal (PGU), el mercado laboral, las tablas de mortalidad y rentabilidad de los fondos en las pensiones, los retiros, entre otras variables, y también hizo proyecciones futuras de los actuales cotizantes. + +Bravo realizó su estudio incluyendo pensionados y no pensionados, con todo su historial de cotizaciones desde mayo de 1981 (o desde la fecha de su afiliación), hasta diciembre de 2022. El valor adicional de esta base, de más de 1 millón de cotizantes, radica también en que se pudo analizar un cohorte de cotizantes que comenzó desde el día 1 (año 1981) a cotizar en el sistema, y que a 2022 ya tenía, potencialmente, 40 años de vida laboral a cuestas. + +La conclusión principal del estudio es que las tasas de reemplazo netas o liquidas asociadas a las pensiones autofinanciadas superan el 80% en el caso de hombres para los pensionados anteriores a los retiros de fondos de pensiones; y, en el caso de las mujeres, las tasas de reemplazo asociadas a las mayores densidades de cotizaciones están cercanas al 60%. + +De acuerdo a David Bravo, esto parece indicar que, en todos los casos, independientemente del tramo de cotizaciones, lo que los y las pensionadas reciben en términos de pensión por sus cotizaciones individuales ahorradas es una proporción alta y cercana a los estándares internacionales. Sin embargo, el economista destaca, que de todas maneras, las pensiones absolutas siguen siendo bajas o insuficientes, enfatizando el rol del mercado laboral en el nivel de remuneraciones, a su vez. + +Por otra parte, al considerar los efectos de la PGU, las tasas de reemplazo son cercanas al 100% para los hombres en los tramos de mayores cotizaciones, siendo muy superiores al 100% en los grupos con mayores lagunas previsionales. En el caso de las mujeres, las tasas son cercanas al 80% en los tramos de mayores cotizaciones para pensionadas entre 2012 y 2019. + +De todos modos, en los datos se aprecia también el positivo impacto que tuvo la introducción del componente solidario y la PGU, específicamente, en las pensiones futuras. “La PGU a los niveles actuales ya mejora las pensiones futuras. Si queremos aumentarla, en mi opinión, la PGU diff --git a/outputs/multi_column/029803ab2f7f83ba727beb70e137fbaad682_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/029803ab2f7f83ba727beb70e137fbaad682_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a8ee75e261cb0130b94e15762ed2e82cd1735aa0 --- /dev/null +++ b/outputs/multi_column/029803ab2f7f83ba727beb70e137fbaad682_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,31 @@ +## The Peninsula Humane Society & SPCA has been caring for unwanted rabbits for decades. Though the numbers of incoming rabbits has been greatly reduced, in part, because of our education efforts, we can further improve with your help. + +![](figure) + +![](figure) + +# Your Questions Answered + +## Why should I spay or neuter my rabbit? + +Many reasons, really. Altered (spayed or neutered) rabbits avoid uterine and testicular cancer, thereby increasing their lifespan. Altered rabbits are also less likely to exhibit obnoxious behaviors, such as spraying, fighting and biting, and can be paired with rabbits of the opposite sex for companionship. + +## Is surgery safe for rabbits? + +Yes! When performed by experienced veterinarians, spaying and neutering can be quite safe. However, as with any surgical or anesthetic procedure for animals (or humans, for that matter) some risk of complications, including death, exist. + +## At what age should rabbits be spayed or neutered? + +Male testicles descend at about 3 ½ months of age, and females reach sexual maturity around 4 months of age. Most veterinarians prefer to wait a little longer before performing surgery to minimize the risks for the rabbit. PHS/SPCA has a minimum age limit of 6 months for male rabbits and one year for female rabbits. + +## I see that your rates are much lower than private practice spay/neuter rates. Does this reflect a lower quality of service? + +If anything, it’s the opposite. Our vets perform far more spay/neuter surgeries than private practice vets; this is our specialty. Also, making spay/neuter affordable for all pet owners is part of our mission. + +## How should I prepare my rabbit for surgery? + +Do not fast your rabbit before its surgery. Rabbits must have food and water available at all times. If your rabbit is overweight, he/she should be placed on a weight reduction diet, under your veterinarian’s supervision. + +## How about post-surgery care? + +After surgery, have your rabbit’s cage ready as usual and separate him/her from your other pets. Neutered males should not be put in contact with unaltered females for at least three weeks after surgery. Do not encourage any exercise and refrain from picking-up your rabbit unnecessarily. Offer your rabbit what he or she normally eats, as well as “treats” (parsley, apples, and carrots). Monitor your rabbit’s appetite, but know that he or she may not be interested in food the night after surgery. Contact your veterinarian if your rabbit does not eat after 24 hours. Check your rabbit’s incision twice a day- it should be free of blood or discharge. Bruising or swelling of the incision/scrotum may occur, but it is normal. You may notice that your female rabbit has two small dark lines, one on each side, parallel to her incision. These are thin tattoo lines to indicate she has been spayed. If a female pulls her stitches out, call the PHS/SPCA Spay & Neuter Clinic for an incision check. diff --git a/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_12_pg1_pg1_repeat1.md b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_12_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0ef3a62169c9065a7f0d001cbea4ee2657fcdcfb --- /dev/null +++ b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_12_pg1_pg1_repeat1.md @@ -0,0 +1,33 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Kepala Bagian Keuangan Bapak LM. Davis, SE. yang dapat menjelaskan sikapnya terhadap hal ini. + +"SOT yang baru ini membuat pegawai bingung karena banyak yang kehilangan jabatan dan sumber penghasilan, lihatlah banyak pejabat yang nyogok untuk sebuah jabatan. SOT ini mungkin niatnya baik tapi nasib pegawai dan pertimbangan kemanusiaan perlu dipikirkan agar SOT ini benar-benar sesuai dengan kebutuhan kabupaten tanpa melupakan pegawai. Apa menjamin dengan SOT yang baru menyebabkan pemda lebih efisien dan responsive? kan tidak semudah itu. jadi perlu kematangan dan pengetahuan yang cukup sebelum hal ini dilakukan" (Hasil wawancara penulis, 6 September 2013). + +Selanjutnya untuk item pernyataan bahwa pemerintah mengembangkan usaha mencari keuntungan (profit oriented) sebagai sumber pendapatan sebanyak 9 orang (13,3%). Dengan demikian dapat dikatakan bahwa sebagian besar responden tidak setuju bila pemerintah mengembangkan usaha mencari keuntungan sebagai sumber pendapatan dan hanya sebagian kecil yang setuju untuk hal ini. + +Dari hasil wawancara penulis dengan beberapa pejabat dan observasi dilapangan menunjukkan bahwa pemerintah tidak bisa disamakan dengan pihak swasta karena misinya berbeda dengan pemerintah. selanjutnya aparat pemerintah banyak yang tidak mempunyai kemampuan wirausaha dan terakhir banyak usaha-usaha yang dijalankan pemerintah rugi, kebocoran dimana-mana, ditambah lagi efisiensi jauh dari yang diharapkan seperti perusahaan-perusahaan milik pemerintah baik dipusat maupun didaerah. Hal ini terungkap dari beberapa hasil wawancara dengan M. Mahyuddin M. ST., M.Si Kasubbag Prasarana Fisik Pemerintahan di Sekretariat Daerah Kabupaten Buton berikut ini: + +"Menurut saya memang sudah saatnya pemerintah berpikir untuk mencari sumber pendapatan baru, apalagi dengan otonomi daerah ini mau tidak mau suka tidak suka kalau mau jalan suatu pemerintah daerah ia harus punya sumber pendapatan yang besar. kita dibengkalis terbantu oleh dana perimbangan minyak jika ini tidak ada, kitapun sama tahu bengkalis menjadi hanyut + +bila kita tidak punya pemikiran mencari sumber pendapatan alternatif selain dana perimbangan." (Hasil wawancara penulis, 6 September 2013). + +Begitulah adanya pemahaman dan pengertian yang beragam dari setiap responden mengenai setiap pernyataan yang ada dengan alasan yang berbeda pula. Setiap orang punya alasan sendiri untuk menjawab setuju ataupun tidak setuju. Itulah gambaran umum jawaban responden terhadap aspek profit oriented yang dikembangkan pemerintah dengan alasannya setuju dan ketidaksetujuan mereka. + +## Persepsi Pejabat Birokrasi Pemerintah dalam Kewirausahaan. + +Aspek Pengetahuan Dan Sikap Terhadap Kewirausahaan + +Tabel IV.8. Aspek Pengetahuan dan Sikap Terhadap Kewirausahaan + +
NoItem PernyataanFrekuensiPersentase (%)
1Pemahaman saya terhadap konsep Entrepreneurial Government sudah baik2029,5
2Pemahaman dan pengetahuan konsep Entrepreneurial Government didapat dari semasa kuliah, membaca buku atau blog saya2333,8
3Konsep Entrepreneurial Government dapat diterapkan kedalam pekerjaan di instansi2536,7
Jumlah68100
+ +Sumber: Data primer diolah tahun 2013 + +Berdasarkan data pada tabel IV.8 terlihat bahwa hasil penilaian dan pandangan responden terhadap aspek pengetahuan dan sikap terhadap kewirausahaan untuk item pemahaman saya terhadap konsep entrepreneurial government sudah baik, sebanyak 20 orang (29,5%). Dengan demikian dapat dikatakan bahwa sebagian besar responden tidak memahami konsep entrepreneurial government dengan baik. + +Berikut ini wawancara penulis dengan Yusniah, S.Sos selaku Kasubag Ketatalaksanaan dan Pengelolaan Data pada Bagian Organisasi dan Kepegawaian yang menggambarkan kesimpulan tersebut: + +"Saya tak tahu apa itu Entrepreneurial Government, memang pernah dengar tapi ya tadi hanya sekilas-sekilas saja, kadang dengar di TV atau baca koran jadi saya tak paham betul mengenai itu apalagi saya cuma tamat SLTA." Saya memang pernah dengar tentang + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_14_pg1_pg1_repeat1.md b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_14_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f3571cf70327ae5cffbeb1f052b6e4756dbaba39 --- /dev/null +++ b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_14_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +dan kreatifitas dari sekedar loyal pada prosedur atau aturan-aturan yang kaku. menunjukkan 19 orang (27,9%). Dengan demikian dapat dikatakan bahwa responden sebagian besar setuju bila diperlukan sebuah inovasi dan kreatifitas dari seorang aparat daripada hanya sekedar loyal dan taat pada aturan yang kaku. Hal ini dimungkinkan karena dalam birokrasi ada yang namanya kewenangan diskresi. Kebanyakan dari pegawai tidak berani untuk mengadakan sebuah inovasi atau bentuk kreatifitas karena hal tersebut dianggap melanggar aturan. Pandangan Hardianti, SE Kasubag. Pembebasan di Setdakab Buton setidak-tidaknya merefleksikan persepsi tersebut. + +"Pegawai yang kreatif dan inovatif sangat jarang kita jumpai dan mereka tidak terbiasa dengan hal itu, mereka hanya terbiasa dengan taat pada aturan, juklak ataupun juknis selain itu dianggap melanggar aturan dan mendapat sanksi. Padahal sebuah inovasi diperlukan agar mencari hal-hal yang terbaik dan paling efisien dalam pemerintahan ini. Kita sebenarnya terus mendorong untuk tumbuhnya inovasi dan kreatifitas pegawai, dengan syarat tidak untuk kepentingan pribadi. Kewenangan untuk diskresi saya berikan pada bawahan saya selama hal itu tidak menyimpang dengan tujuan yang telah ditetapkan, karena saya yakin kekakuan pada aturan akan menyebabkan kita lambat dalam merespon kondisi lapangan yang selalu berubah-ubah". (Hasil wawancara penulis, 10 September 2013). + +Selanjutnya untuk item pernyataan Mempunyai kemampuan mengambil keputusan dan mempunyai kewenangan dalam diskresi power, terdapat 20 orang (29,5%). Dari hasil penilaian tersebut terlihat bahwa sebagian besar responden setuju bila mereka mempunyai kemampuan dalam mengambil keputusan dan mempunyai kemampuan diskresi power. Jabatan yang mereka pegang tentu saja ada kewenangan yang terkandung di dalamnya dan kita selalu dihadapkan dengan pengambilan keputusan. Hal ini terungkap dari hasil wawancara penulis dengan salah satu pejabat eselon III di Setdakab: + +"Dalam sebuah jabatan jelas sudah terkandung kewenangan didalamnya ada tugas, kewajiban yang harus kita selesaikan + +sebagai rasa tanggungjawab dan kita selalu dihadapkan dengan pengambilan keputusan-keputusan sesuai dengan jabatan yang kita pegang". + +## Aspek Sosialisasi Dari Prinsip Kewirausahaan + +Tabel IV.10. Aspek Sosialisasi Prinsip Kewirausahaan + +
NoIndikatorFrekuensiPersentase (%)
1Sering mengikuti seminar, workshop dan simposium yang berhubungan dengan kewirausahaan2130,8
2Dapat struktural yang saya ikuti telah mengajarkan konsep entrepreneurial government2333,9
3Pemerintah daerah telah mengenalkan konsep entrepreneurial government ini dalam sebuah kegiatan sosialisasi seperti saat ini2435,3
Jumlah68100
+ +Sumber: Data primer diolah tahun 2013 + +Berdasarkan data pada tabel IV.10 terlihat bahwa hasil penilaian dan pandangan responden terhadap aspek sosialisasi dari prinsip kewirausahaan untuk item pernyataan Sering mengikuti seminar, workshop dan simposium yang berhubungan dengan entrepreneurial government 21 orang (30,8%). Dengan demikian dapat dikatakan bahwa sebagian besar responden belum pernah mengikuti acara-acara yang membahas konsep-konsep pemerintahan yang bergaya wirausaha. Dapat disimpulkan kalau sebagian besar pejabat pemda banyak yang tidak mengetahui dan memahami ide dan konsep pemerintahan yang bergaya wirausaha. + +Berikut ini wawancara penulis dengan Bapak LM. Rahimin Baharuddin, SP Selaku Kasubag. Sumber Daya Alam pada Bagian Perencanaan di Sekretariat Daerah Kabupaten Buton: + +"Kami yang duduk di eselon IV ini jarang ikut-ikut seminar atau lokakarya apalagi acara-acaranya yang dijakarta, itu hanya buat eselon II atau sekali-kali eselon III, jadi terus terang saja kami banyak tak tahu tentang perkembangan dan perubahan yang terjadi, palingan hanya sekedar tahu dikit-dikit saja. (Hasil wawancara penulis, 10 September 2013). + +Dari ungkapan tersebut dapat kita tarik sebuah kesimpulan bahwa untuk pejabat rendah jarang sekali diberi kesempatan untuk mengikuti seminar ataupun lokakarya sehingga sudah sewajarnya kalau pengetahu- + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_16_pg1_pg1_repeat1.md b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_16_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..82d6a7e4bfc50090e08e40fb1cf55cf7b1ee31a2 --- /dev/null +++ b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_16_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +banyak yang setuju bila dalam organisasi pemda budaya paternalistik masih mengakar sangat kuat. + +Pemerintahan yang bergaya wirausaha tidak memberikan tempat pada budaya paternalistik, hirarki yang kaku dan terpaku pada aturan-aturan yang permanen. Keluwesan pada aturan, inovasi, kreatifitas, efisiensi, efektifitas dan akuntabilitas selalu menjadi pendorong untuk terciptanya pemerintahan yang bergaya wirausaha selama tidak bertentangan dengan misi yang diemban organisasi. + +Berikut ini wawancara penulis Bapak Marjani Wali, S.Sos., M.Msip selaku Staf Ahli Bupati bidang Pembangunan di Sekretariat Daerah Kabupaten Buton sebagai berikut: + +"Salah satu masalah penting yang kita hadapi dalam membangun dan mengembangkan pemerintahan yang bergaya wirausaha adalah adanya budaya paternalistik yang mengakar kuat dalam pemerintahan saat ini. Hubungan atasan bawahan yang kaku selalu mematikan inovasi dan kreatifitas. Yang terjadi adalah ketakutan dan ketergantungan pegawai yang besar pada atasan, pegawai tidak berani mengambil keputusan sebelum meminta petunjuk dengan atasan". (2 September 2013). + +Untuk item pernyataan bahwa pemerintah daerah telah mendorong dan mengembangkan jiwa serta spirit kewirausahaan dalam budaya kerja, 17 orang (25%). Dari hasil penilaian tersebut terlihat bahwa pemerintah daerah tidak mengembangkan dan mendorong konsep kewirausahaan dalam budaya kerja. Berikut hasil wawancara penulis dengan Jafar, S.AP selaku Kasubag. Pengumpulan Data Layanan Informasi dan Publikasi di Sekretariat Daerah Kabupaten Buton; + +"Seingat saya belum ada sebuah usaha dari pemerintah daerah untuk mengembangkan semangat kewirausahaan dilingkungan organisasi pemda" Kita bisa contohkan sistem insentif bagi pegawai yang ada selama ini tidak mencerminkan spirit kewirausahaan karena insentif yang diberikan tidak didasarkan pada kinerja seseorang". (4 September 2013). + +Terlihat jelas dari hasil wawancara bahwa pemerintah daerah belum mengembangkan semangat kewirausahaan dalam budaya kerja birokrasinya. Salah satu strategi + +dalam mengembangkan kewirausahaan adalah strategi budaya. Strategi ini dilakukan dengan mengubah kebiasaan, menyentuh perasaan dan mengubah pikiran atau pandangan seseorang terhadap suatu hal. + +Tanggapan responden terhadap pernyataan bahwa pemerintah daerah telah mengembangkan sistem insentif yang mendorong motivasi dan etos kerja pegawai menunjukkan 17 orang (25%). Dengan demikian dapat dikatakan bahwa responden berpendapat bahwa pemerintah daerah belum mengembangkan sistem insentif yang mendorong motivasi dan etos kerja pegawai. Pandangan Zuhri Maryam Zain, SAP Kasubag pada Bagian Kesra di Sekretariat Daerah Kabupaten Buton setidak-tidaknya merefleksikan persepsi tersebut. + +"Sistem insentif belum dikembangkan oleh pemerintah daerah, pegawai yang banyak proyek bisalah dapat rezeki lebih sedangkan yang pegawai yang tak ada kegiatan tak dapat apa-apa. Uang insentif tambahan penghasilan buat pegawai pembagiannya sama rata saja. Tidak ada pemikiran untuk mengubah kebiasaan yang sudah mengakar dalam organisasi pemerintah daerah" (5 September 2013). + +Selanjutnya untuk item pernyataan bahwa pemerintah daerah mengembangkan bentuk dan sifat komunikasi dua arah dan terbuka dalam suasana kerja yang kondusif, terdapat 19 orang (27,9%). Dari hasil penilaian tersebut terlihat bahwa pemerintah belum mengembangkan bentuk dan sifat komunikasi dua arah dan terbuka dalam suasana kerja yang kondusif. Berikut hasil wawancara dengan Ramli Adia, S.Kom Kasubag. Pada Bagian Kesra di Sekretariat Daerah Kabupaten Buton. + +"Kita sama atasan sangat segan dan kurang komunikasi, apalagi untuk menegur atasan adalah sangat sulit, Kebanyakan atasan merasa orang yang paling pintar dan tanpa koreksi. Secara umum kayak begitu adanya. Pemerintah daerah belum ada usaha yang serius dan sungguh-sungguh untuk mengembangkan bentuk komunikasi yang terbuka pada semua pegawai maupun antara atasan dan bawahan, budaya itu belum terbangun" (5 September 2013). + +Dari ungkapan tersebut dapat kita + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_17_pg1_pg1_repeat1.md b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_17_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ab8a3ff73bfa5f1c79c73932f5e2d863ed3a2883 --- /dev/null +++ b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_17_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +simpulkan bahwa pembentukan budaya komunikasi yang dua arah dan terbuka belum dikembangkan oleh pemerintah daerah. Hal ini dikarenakan pengembangan budaya merupakan suatu yang sangat sulit dan memerlukan waktu yang cukup lama. Budaya yang berkembang dalam sebuah lingkungan akan menentukan menentukan cara pandang seseorang terhadap sesuatu hal. Budaya juga akan memberikan penilaian tentang penerimaan ataupun penolakan terhadap sebuah ide atau konsep yang akan dikembangkan ke dalam sebuah organisasi, seperti pengembangan konsep dan nilai-nilai pemerintahan yang bergaya wirausaha dalam organisasi pemda. + +## IV. PENUTUP + +### Kesimpulan + +Pandangan dan pengetahuan pejabat birokrasi terhadap konsep kewirausahaan, sebagaimana ditunjukkan oleh penelitian ini masih sangat rendah. Kendati pandangan pejabat pemerintah daerah Kabupaten Buton tidak mempresentasikan pandangan pejabat birokrasi, temuan dari penelitian ini setidaknya memberikan gambaran mengenai rendahnya pengetahuan pejabat birokrasi terhadap ide, konsep maupun paradigma baru penyelenggaraan pemerintahan modern. + +Dilihat dari semua indikator yang digunakan dalam penelitian ini, pemahaman dan pengetahuan pejabat pemda Kabupaten Buton terhadap konsep pemerintahan yang bergaya wirausaha (entrepreneurial government) masih sangat rendah, sebagaimana ditunjukkan dengan rendahnya pemahaman dan pengetahuan tentang prinsip costumer oriented (pemerintah yang berorientasi pada masyarakat). Adanya penolakan terhadap ide citizen carter (piagam warganegara) dan konsep customer choice (pilihan pelanggan) dalam hal pelayanan publik. Selanjutnya pejabat Pemda Kabupaten Buton masih menginginkan pemerintah yang mengambil alih semua kegiatan-kegiatan pemenuhan kebutuhan publik dan tidak adanya kepercayaan pada pihak swasta dan masyarakat dalam mengelolanya. Selanjutnya untuk konsep efisiensi anggaran pemerintah dengan adanya anggaran yang didasarkan pada kinerja hanya sebagian pejabat yang memahaminya, dan + +sebagian lagi tidak memahaminya. Terhadap sistem insentif dalam anggaran pemerintah sebagian besar pejabat tidak memahaminya. + +Beberapa pemikiran yang inovatif dan kreatif dalam pemerintahan yang wirausaha seperti pola kemitraan dengan swasta, ide sunset law (pembatasan berlakunya sebuah peraturan), adanya komisi peninjau peraturan (review commissions) tidak dipahami secara mendalam oleh pejabat pemerintah kabupaten Bengkalis. Kemudian konsep renstra dalam kebijakan pemerintah sebagian besar pejabat memahaminya dengan baik. Untuk ide penyusunan SOT (struktur organisasi dan tatalaksana) dalam organisasi pemda banyak terjadi penolakan oleh mereka yang dirugikan dengan penataan tersebut, dan diterima oleh mereka yang diuntungkan. + +Dilihat dari aspek budaya birokrasi yang sangat kental dengan budaya paternalistik dan perkoncoan dapat menjelaskan begitu sulitnya konsep ini untuk dikembangkan. Hubungan antara atasan dan bawahan yang kaku, komunikasi searah yang tidak sehat, sistem insentif yang tidak menumbuhkan inovasi dan kreatifitas pejabat menyebabkan rasa malas dari setiap pejabat untuk mengembangkan pengetahuannya. Dalam laporan ini ditemukan bahwa yang mengikuti seminar-seminar, lokakarya dan diklat-diklat fungsional hanya untuk pejabat eselon III yang dekat dengan kekuasaan dan untuk pejabat eselon II sedangkan pejabat eselon IV jarang sekali mengikutinya. + +### Saran + +Dengan memperhatikan temuan-temuan ini, bisa disimpulkan masalah yang dihadapi oleh pejabat birokrasi dalam upaya meningkatkan pengetahuan mereka dalam memahami konsep pemerintahan yang bergaya wirausaha (entrepreneurial government). Upaya peningkatan pengetahuan pejabat adalah sangat kompleks dan memiliki dimensi yang amat banyak. Upaya ini menuntut intervensi pemerintah daerah yang besar dalam semua dimensi permasalahan secara holistik. Adapun upaya yang dapat dilakukan dan perlu mendapat perhatian serius yaitu: + +Perlunya bagi pemerintah daerah Kabupaten Buton untuk mengirimkan pejabat- + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..97b776b571de473d378047a1d206bc4db6cde122 --- /dev/null +++ b/outputs/multi_column/02a3e23da54b82c414d272051b0b5d8f44d8_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,57 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +dalam rangka pelaksanaan otonomi daerah. + +Secara akademis diharapkan hasil penelitian ini dapat dijadikan salah satu pijakan bagi penelitian selanjutnya, terutama yang berhubungan dengan penerapan ide-ide baru dalam penyelenggaraan pemerintahan yaitu semangat kewirausahaan. + +## II. METODE PENELITIAN + +### Jenis Penelitian + +Dalam penelitian ini tidak ada penegasan yang jelas tentang pendekatan yang akan digunakan, baik pendekatan positivistik maupun pendekatan naturalistik, tetapi mencoba untuk mengkombinasikan kedua pendekatan tersebut. + +Penelitian ini adalah penelitian deskriptif kualitatif dengan menggunakan metode survei yakni suatu jenis penelitian yang dimaksudkan untuk mengumpulkan informasi mengenai status atau gejala yang ada yakni keadaan menurut gejala apa adanya pada saat penelitian dilakukan (Suharsimi Arikunto, 1996:309). + +Penelitian ini dimaksudkan berupaya memahami, menggambarkan dan melakukan persepsi dari pejabat struktural pemerintah daerah Kabupaten Buton dalam menerima dan memahami ide *entrepreneurial government* serta mengetahui faktor-faktor yang menjelaskan persepsi pejabat tersebut terhadap ide *entrepreneurial government*. + +### Variabel Penelitian + +Variabel pada penelitian ini terdiri dari variabel bebas (variabel independent) dan variabel terikat (dependent). Variabel bebas adalah Kewirausahaan. Sedangkan variabel terikat adalah Persepsi Pejabat Birokrasi. Secara skematis model analisis yang akan dilakukan dalam mengkaji *entrepreneurial government* dalam persepsi pejabat birokrasi dan faktor-faktor yang menjelaskannya adalah sebagai berikut: + +### Definisi Konsep + +Definisi konsep dari masing-masing variabel adalah sebagai berikut + +1) *Entrepreneurial Government* adalah suatu birokrasi pemerintahan yang memiliki jiwa dan semangat kewirausahaan dengan karakteristik berorientasi pada kebutuhan masyarakat (customer oriented), efisien, inovatif, responsive dan kompetitif dalam rangka penyelenggaraan tugas dan fungsinya. + +2) Persepsi pejabat birokrasi adalah pemahaman dan pengetahuan pejabat Pemda kabupaten terhadap ide dan konsep dari *Entrepreneurial Government*. + +3) Kompetensi pejabat adalah kecakapan dan kemampuan yang dimiliki oleh pejabat dalam melaksanakan tugas dan kewajibannya. + +4) Sosialisasi adalah proses belajar untuk mengetahui dan mengenal sesuatu yang terefleksi kedalam persepsi, sikap dan tingkah laku seseorang. + +5) Budaya birokrasi adalah sistem atau seperangkat nilai yang memiliki, simbol, orientasi nilai, keyakinan, dan pengetahuan yang diaktualisasikan kedalam sikap, tingkah laku dan perbuatan yang dilakukan oleh setiap pejabat. + +### Definisi Operasional + +#### Entrepreneurial Government + +1) Variabel *entrepreneurial government* dapat diukur dengan menggunakan indikator. + +a) Berorientasi pada masyarakat (customer oriented) + +b) Efisiensi dalam penggunaan anggaran + +c) Inovasi dan kreatifitas + +d) Kompetitif dalam penyelenggaraan pelayanan publik + +2) Persepsi pejabat birokrasi adalah pemahaman, pengetahuan dan penerimannya terhadap ide dan konsep dari *entrepreneurial government* oleh pejabat birokrasi. Persepsi pejabat birokrasi akan diukur dari: + +a) Pemahaman dari pejabat pemda terhadap konsep *entrepreneurial government* + +b) Dilihat dari keikutsertaan pejabat pemda dalam pelatihan dan kursus yang berhubungan dengan penerapan kewirausahaan sektor publik + +c) Tingkat penerimaan terhadap konsep *entrepreneurial government* dalam diri para + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_10_pg1_pg1_repeat1.md b/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_10_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..74732ba0cd164a40ee7770c290e86280c9cd4f77 --- /dev/null +++ b/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_10_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +have distinct Raman spectra. This supports the interpretation that metamictization is a disorder phenomenon, the end product of which is a glassy state with zircon composition. + +The laser-induced fluorescence observed in zircon is attributed to photoluminescence of trivalent REE ions that substitute for \(Zr^{4+}\) (e.g., Marfunin 1979). The fine structure of emission lines of the REE depends on the local crystal field around the REE ion and is thus unique to each host mineral. The only detailed study of laser-excited fluorescence of REE ions in a mineral (fluorite) was conducted by Burruss et al. (1992), who established a correlation between the REE concentration and the intensity of the fluorescence emission. All terrestrial and extraterrestrial samples of zircon that contain REE exhibit such laser-induced fluorescence emissions at specific wavelengths; those wavelengths are exactly the same for different zircon samples. A full analysis of these REE emission spectra will be reported in a subsequent paper. In this paper, we mention only that the 488 nm laser-excited fluorescence bands observed in zircon essentially define three groups: (1) from ~539 to ~558 nm, caused by \(Eu^{3+}\) , \(Er^{3+}\) , and \(Tb^{3+}\) , (2) from ~568 to ~582 nm, caused by \(Dy^{3+}\) , and (3) several more isolated bands at 604, 616, 650, and 660 nm, caused by \(Eu^{3+}\) . In comparison with bands of other samples of lunar and terrestrial zircon (unpublished data from our laboratory), the fluorescence bands in the zoned, single-crystalline zircon of this study are weak (even on the trace element-rich side of the crystal), consistent with the relatively low concentrations of REE in this sample. There is a strong linear correlation between the intensity of the emission line at 546 nm (caused by \(Er^{3+}\) ) and the Er concentration as determined by ion microprobe analysis. The general applicability and usefulness of this finding needs testing, especially because the presence of crystalline disorder may complicate the quantitative interpretation of REE photoluminescence. + +Quantification of the degree of structural disorder using Raman microprobe analysis may lead to a better understanding of the thermal history and the redistribution of radiogenic Pb, Th, U and other intermediate daughter products related to the expansion of the zircon structure owing to metamictization. Further studies of zircon need to address the following questions: (1) Can the observed variations in the Raman spectra of zircon be calibrated against the U concentration or the sum of heavy trace elements present in any given sample? (2) Can the interpretation of Raman spectra provide a general means of quantifying the degree of metamictization? (3) Can the Raman microprobe be used to quantify and evaluate the degree of self-annealing over extended geologic time, as suggested to occur by Weber et al. 1994? (4) Is there a generally applicable correlation between REE concentrations and the intensity of the laser-induced fluorescence emissions? (5) Does the strong correlation between Raman parameters and trace element concentrations in the + +lunar zircon also hold for zircon that has been subjected to terrestrial igneous and metamorphic processes? + +ACKNOWLEDGMENTS + +We are grateful to Trevor Ireland for providing a series of zircon standards with known Th and U concentrations. We also thank Conel Alexander for his help with ion microprobe data analysis. We thank Rodney Ewing and Richard Hinton for their thorough and very helpful reviews of the manuscript. Partial funding for this work was provided by NASA grant NAGW-3343 (to B.L.J.), NSF grant GER-9023520 (to B.W.), NSF grant EAR-9417677 (to B.W.), and NASA grant NAGW-3371 (to E.Z.). + +REFERENCES CITED + +Armstrong, J.T. (1988) Quantitative analysis of silicate and oxide minerals: Comparison of Monte-Carlo, ZAF, and phi-rho-Z procedures. Microbeam Analysis, 239–246. Black, L.P., Kinny, P.D., and Sheraton, J.W. (1991) The difficulties of dating mafic dykes: An Antarctic example. Contributions to Mineralogy and Petrology, 109, 183–194. Burruss, R.C., Ging, T.G., Eppinger, R.G., and Samson, I.M. (1992) Laser-excited fluorescence of rare earth elements in fluorite: Initial observations with a laser Raman microprobe. Geochimica et Cosmochimica Acta, 56, 2713–2723. Bursill, L.A., and McLaren, A.C. (1966) Transmission electron microscope study of natural radiation damage in zircon ( \(ZrSiO_4\) ). Physica Status Solidi, 13, 331–343. Chakoumakos, B.C., Murakami, T., Lumpkin, G.R., and Ewing, R.C. (1987) Alpha-decay-induced fracturing in zircon: The transition from crystalline to the metamict state. Science, 236, 1556–1559. Compston, W., Williams, I.S., and Meyer, C. (1984) U-Pb geochronology of zircons from lunar breccia 73217 using a sensitive high mass-resolution ion microprobe. Proceedings of the 14th Lunar and Planetary Science Conference, in Journal of Geophysical Research, 89, B525–B534. ——— (1989) The problem of lunar initial Pb. Lunar and Planetary Science, XX, 179–180. Crozaz, G., and Zinner, E. (1986) Quantitative ion microprobe analysis of the rare earth elements in minerals. Scanning Electron Microscopy, II, 369–376. Dawson, P., Hargreave, M.M., and Wilkinson, G.R. (1971) The vibrational spectrum of zircon ( \(ZrSiO_4\) ). Journal of Physics: Solid State Physics, 4, 240–256. Ellsworth, S., Navrotsky, A., and Ewing, R.C. (1994) Energetics of radiation damage in natural zircon ( \(ZrSiO_4\) ). Physics and Chemistry of Minerals, 21, 140–149. Ewing, R.C., Lutze, W., and Weber, W.J. (1995) Zircon: A host-phase for the disposal of weapons plutonium. Journal of Materials Research, 10, 243–246. Friedlander, G., Kennedy, J.W., Macias, E.S., and Miller, J.M. (1981) Nuclear and radiochemistry (3rd edition), 684 p. Wiley, New York. Hinton, R.W., and Meyer, C. (1991) Ion microprobe analysis of zircon and yttrobetafite from a lunar granite. Lunar and Planetary Science, XXII, 575–576. Hinton, R.W., and Upton, B.G.J. (1991) The chemistry of zircon: Variations within and between large crystals from syenite and alkali basalt xenoliths. Geochimica et Cosmochimica Acta, 55, 3287–3302. Hobbs, L.W., Clinard, F.W., Zinkle, S.J., and Ewing, R.C. (1994) Radiation effects in ceramics. Journal of Nuclear Materials, 216, 291–321. Holland, H.D., and Gottfried, D. (1955) The effect of nuclear radiation on the structure of zircon. Acta Crystallographica, 8, 291–300. Ireland, T.R., Fahey, A.J., and Zinner, E.K. (1991) Hibonite-bearing microspherules: A new type of refractory inclusions with large isotopic anomalies. Geochimica et Cosmochimica Acta, 55, 367–379. Jarosevich, E., and Boatner, L.A. (1991) Rare-earth element reference samples for electron microprobe analysis. Geostandard Newsletter, 15, 397–399. Jolliff, B.L. (1991) Fragments of quartz monzodiorite and felsite in Apollo + +Jolliff, B.L. (1991) Fragments of quartz monzodiorite and felsite in Apollo + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..60fdc46277de0ec31338a65fdf79ac3b7c5d4ff8 --- /dev/null +++ b/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Zircon occurs as a widespread accessory mineral in almost all types of terrestrial rocks, but it also occurs in meteorites and lunar rocks. It is one of the earliest accessory minerals to crystallize in a magma and continues to precipitate over long periods of time and ranges of temperature. Individual crystals can develop extensive chemical zonation, which reflects the changing chemical composition of residual magma (Hinton and Upton 1991). + +As summarized by Speer (1982), the chemical composition of zircon is complex, and besides Hf, which is always present (concentrations up to 7 wt%), more than 50 other elements have been found in zircon. The most important ions substituting for \([^8]\text{Zr}^{4+}\) are \(\text{Hf}^{4+}\) , \(\text{U}^{4+}\) , \(\text{Th}^{4+}\) , \(\text{Y}^{3+}\) , and the \(\text{REE}^{3+}\) . Only \(\text{P}^{5+}\) and sometimes \(\text{Nb}^{5+}\) and \(\text{Al}^{3+}\) can replace \(\text{Si}^{4+}\) in its tetrahedral site. A close correlation between the concentrations of atoms of P and REE (including Y) in many zircon crystals suggests that most of the REEs are present in the form of phosphate molecules (i.e., \(\text{REEPO}_4\) ) as in xenotime ( \(\text{YPO}_4\) ). + +The incorporation of various elements substituting for \(\text{Zr}^{4+}\) changes the physical characteristics of the mineral and results in optical zonation, metamictization, and fluorescence. Transmission electron microscopy on zoned single crystals of zircon reveals that some of the zones are perfectly crystalline, whereas other zones show some structural damage or are even amorphous (Murakami et al. 1991). Metamictization in zircon results from \(\alpha\) -decay events in the natural radioactive decay of \(^{238}\text{U}\) , \(^{235}\text{U}\) , and \(^{232}\text{Th}\) and their daughter products. Specifically, the high-energy \(\alpha\) particle produces hundreds of atomic displacements with a range of \(\sim 10 \mu\text{m}\) , and the energetic recoil nucleus, with a range of \(\sim 20 \text{ nm}\) , produces localized damage with about 1000 atomic displacements (Weber et al. 1994). Zircon may contain substantial concentrations of U and Th and may therefore be exposed to doses as high as \(10^{15}\) – \(10^{16} \alpha\) -decay events per milligram of zircon over its geologic life time. The physical changes in zircon that result from radiation damage include an increase in unit-cell dimensions and decreases in density and hardness (Holland and Gottfried 1955; Speer 1982). The different interference colors frequently observed in thin sections of zircon are known to be due to differing levels of \(\alpha\) -decay damage. Increasing radiation damage decreases birefringence until the fully metamict crystal is optically isotropic (Sahama 1981). The totally metamict state is a structure that appears to be amorphous when analyzed by X-ray and electron diffraction techniques (e.g., Yada et al. 1981). + +SAMPLE + +We report here the analytical results obtained on a single zoned zircon grain in a thin section of a 23 mg lithic fragment, lunar sample 14161,7069, from an Apollo 14 soil. This sample is a partially recrystallized impact brecc- + +cia of quartz-monzodioritic (QMD) bulk composition and mineralogy, including regions of potassium feldspar-bearing granophyre (Jolliff et al. 1991; Jolliff 1991). The unusually high incompatible trace element concentrations (ITE \(\approx 2 \times\) average high-K KREEP; Warren 1989), low siderophile-element concentrations, and uniform major mineral compositions indicate that this breccia is monomict (Jolliff 1991; Warren 1993). The original 23 mg sample comprised \(\sim 30\) vol% pyroxene (average \(\text{En}_{24}\text{Fs}_{68}\text{Wo}_8\) and \(\text{En}_{20}\text{Fs}_{52}\text{Wo}_{28}\) ), \(\sim 30\%\) plagioclase ( \(\text{An}_{78-61}\) ), 23% quartz plus silica-potassium feldspar granophyre, 11% barian potassium feldspar, 3.7% phosphates (whitlockite, apatite), 2.4% ilmenite, approximately 0.6% zircon, and a trace of fayalite (Jolliff 1991). Baddeleyite ( \(\text{ZrO}_2\) ), zirconolite \([(\text{Fe}, \text{Ca}, \text{REE})(\text{Zr}, \text{Ti}, \text{REE})_3\text{O}_7]\) ; Wark et al. 1973], and yttrobetafite \([(\text{Ca}, \text{Fe}, \text{Y}, \text{REE}, \text{U}, \text{Th})_2-(\text{Ti}, \text{Nb})_2\text{O}_7]\) ; Meyer and Yang 1988], which have been found in other evolved lunar rocks (e.g., Smith and Steele 1976), were not found in the thin section of 14161,7069; however, the high bulk Th concentration of the sample (44 ppm; Jolliff 1991) suggests the presence in the rock sample of a Th-rich phase. Sample 14161,7069 was derived from a rock that was brecciated by a meteorite impact at \(\sim 4 \text{ Ga}\) . We suspect the zircon to be older, perhaps as old as 4.1–4.35 Ga, by analogy to other samples of lunar granite and quartz monzodiorite (Compston et al. 1984; Shih et al. 1985, 1993; Meyer et al. 1989b, 1991). + +The zircon grain we selected is a clast (about \(200 \times 80 \mu\text{m}\) ), a fragment of an originally larger crystal, and was analyzed in a polished thin section of \(\sim 10\) – \(15 \mu\text{m}\) thickness. The mounting medium was Araldite, which does not show any laser-induced fluorescence and thus does not interfere with a successful interpretation of the Raman spectra obtained from the sample. The zircon grain is fractured, but it is free of mineral inclusions (Figs. 1a and 1b). Fractures extend into the surrounding matrix but appear to be related to the sample's impact history, not to radiation damage in the zircon. In cross-polarized light, zoning appears as a change in interference colors across the zircon grain, and in the backscattered electron image (Fig. 1b), the bright area on the right side of the grain indicates a high concentration of elements heavier than Zr, such as U, Th, and REE. From the optical appearance in cross-polarized light, and from the backscattered electron image, we inferred this grain to be zoned in chemical composition. + +ANALYTICAL CHARACTERIZATION + +The chemical composition and some vibrational spectroscopic characteristics were determined with an ion microprobe, an electron microprobe, and a Raman microprobe. All three microprobe techniques were applied to the same five points labeled A, B, C, D, and E (Fig. 1c) to characterize chemical and structural variations normal to the optical zoning of the grain. The individual measurement points can be seen easily in the backscattered electron image (Fig. 1b) that was obtained after the sam- + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..77a334ec937ebcf874c19cb69450f603771e53ae --- /dev/null +++ b/outputs/multi_column/02e31046996b59b4997b8413f09ae163ade5_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +TABLE 1. Composition of zircon in lunar sample 14161,7069 + +
A B C D E EMP Avg*
Oxides (wt%) by EMP, except as noted
SiO2 32.5 ± 0.18** 32.8 ± 0.18 32.8 ± 0.18 32.6 ± 0.18 32.7 ± 0.18 32.4(0.54)
ZrO2 66.2 ± 0.54 65.1 ± 0.54 66.5 ± 0.55 65.8 ± 0.55 66.3 ± 0.54 65.9(1.18)
HfO2 1.28 ± 0.08 1.37 ± 0.08 1.22 ± 0.08 1.28 ± 0.08 1.24 ± 0.08 1.18(0.06)
Al2O3 <0.05 <0.05 <0.05 <0.05 <0.05 0.02(0.05)
Y2O3 0.07 ± 0.03 0.16 ± 0.03 0.23 ± 0.03 0.28 ± 0.04 0.34 ± 0.05 0.19(0.09)
FeO 0.10 ± 0.01 0.02 ± 0.01 0.02 ± 0.01 0.05 ± 0.01 0.06 ± 0.01 0.10(0.09)
P2O5 0.05 ± 0.01 0.09 ± 0.01 0.13 ± 0.02 0.16 ± 0.02 0.18 ± 0.02 0.11(0.05)
Ln2O3† 0.05 0.08 0.13 0.16 0.16 0.12(0.08)
Sum 100.3 99.6 101.1 100.4 101.0 100.0
Trace elements (parts per million) by SIMS
P 227 ± 13 380 ± 13 566 ± 13 715 ± 14 766 ± 16
Ca 38 ± 8 24 ± 2 63 ± 10 125 ± 5 70 ± 5
Sc 49 ± 10 58 ± 12 59 ± 12 69 ± 14 72 ± 14
Ti 59 ± 2 66 ± 2 80 ± 4 79 ± 3 161 ± 5
Y 776 ± 7 1250 ± 9 2136 ± 10 2519 ± 14 2660 ± 15
Ba 1.8 ± 0.4 1.1 ± 0.3 1.8 ± 0.5 2.7 ± 0.5 7.5 ± 1.0
La 0.2 ± 0.05 0.1 ± 0.05 0.4 ± 0.1 2.4 ± 0.2 0.4 ± 0.1
Ce 0.7 ± 0.1 0.5 ± 0.1 1.7 ± 0.2 6.7 ± 0.6 2.3 ± 0.3
Pr 0.1 ± 0.05 0.1 ± 0.05 0.3 ± 0.1 1.1 ± 0.1 0.6 ± 0.1
Nd 0.9 ± 0.1 1.5 ± 0.1 4.9 ± 0.3 7.6 ± 0.5 7.3 ± 0.6
Sm 2.0 ± 0.2 3.3 ± 0.3 8.3 ± 0.5 11 ± 1 10 ± 1
Eu 0.05 ± 0.02 0.03 ± 0.02 0.12 ± 0.06 0.03 ± 0.06 0.03 ± 0.10
Gd 14 ± 1 23 ± 1 49 ± 1 72 ± 1 68 ± 2
Tb 3.3 ± 0.3 5.9 ± 0.4 11 ± 1 17 ± 1 14 ± 1
Dy 58 ± 1 90 ± 2 167 ± 3 222 ± 3 213 ± 4
Ho 22 ± 1 35 ± 1 60 ± 1 77 ± 1 78 ± 2
Er 113 ± 2 171 ± 2 291 ± 4 344 ± 4 358 ± 4
Tm 23 ± 1 36 ± 1 55 ± 1 68 ± 1 71 ± 2
Yb 197 ± 3 286 ± 5 438 ± 6 499 ± 5 540 ± 9
Lu 30 ± 2 8 ± 4 14 ± 5 76 ± 3 15 ± 7
Th 6 ± 0.5 11 ± 0.5 21 ± 1 29 ± 2 31 ± 2
U 21 ± 1 31 ± 2 44 ± 2 51 ± 2 55 ± 2
Calculated Th and U concentrations (ppm) at 4.0 Ga
Th 7.3 13 26 35 38
U 46 69 98 113 122
Calculated cumulative \(\alpha\)
\(\sum \alpha\) \(0.52 \times 10^{15}\) \(0.77 \times 10^{15}\) \(1.1 \times 10^{15}\) \(1.3 \times 10^{15}\) \(1.4 \times 10^{15}\)
+ +* Average of 58 electron microprobe analyses (not normalized). Parentheses contain one standard deviation values; these values reflect compositional zoning, so they exceed analytical uncertainty. + +**Analytical uncertainty for data points A–E (± values) represents one standard deviation on the basis of counting statistics. + +† \(Ln_2O_3\) , lanthanides, determined by SIMS; see individual elements for analytical uncertainty. \(Ln_2O_3\) value was summed for all trivalent lanthanides and extrapolated for those not measured. + +row-line fluorescence spectra to be recorded on a micrometer scale in zoned minerals. The mechanical configuration of the high-resolution monochromator in combination with an argon ion laser as excitation source makes it possible to monitor the fluorescence-emission spectra between the wavelength of excitation (488 or 514 nm) and 850 nm. In general, laser-induced fluorescence is an undesired phenomenon in Raman spectroscopy because it typically interferes with and overwhelms the desired Raman spectroscopic information to the extent that the Raman spectrum cannot be interpreted. However, there are certain transitions of trace element ions, e.g., certain trivalent REE ions, that do not overlap or interfere with the Raman peaks, and whose fluorescence emission spectrum can be monitored in addition to the Raman spectrum. + +Six of the observed peaks in the Raman spectrum of pure zircon (Fig. 2a) were theoretically assigned by Dawson et al. (1971) according to a full crystal-field analysis + +of the silicate tetrahedra in a crystalline structure with a \(D_{4h}\) point-group symmetry (Table 2). The four highest frequency modes are internal stretching and bending vibrations of the \((SiO_4)^{4-}\) tetrahedra; whereas, the modes at 224 and 201 \(\Delta \text{cm}^{-1}\) are lattice modes. The intensity of the bands with the \(E_g\) symmetry (see Table 2) depends on the orientation of the zircon crystal with respect to the polarization plane of the exciting laser light. + +The optical spectrum of zircon obtained with a laser Raman microprobe consists not only of the Raman scattering from allowed vibrational modes but also of the structure- and site-specific fluorescence of trivalent REE ions ( \(REE^{3+}\) ). Many terrestrial zircon samples yield Raman spectra that are substantially different from the one predicted from the crystalline structure and obtained for pure \(ZrSiO_4\) (Jolliff et al. 1995; Nasdala et al. 1995). The Raman peaks are frequently shifted substantially downward or upward in position, the peaks are wider, and additional peaks (which are caused by laser-induced flu- + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/02ef468d6658a2cc7878397e68640fe0357f_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/02ef468d6658a2cc7878397e68640fe0357f_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..03c5708b4aa474814731161fdf2c7e144741482f --- /dev/null +++ b/outputs/multi_column/02ef468d6658a2cc7878397e68640fe0357f_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,37 @@ +![](figure) + +![](figure) + +Fig. 4. Reputation checking during the publication process + +## B. Other Services + +When a peer is connected to the network, services (publication of contents, search, data download...) are achieved by sending requests to the other peers. In Kademlia [13] this is done in two phases. Firstly, Kademlia REQ are sent to find nodes which are potentially able to deliver the service (according to their place in the DHT). This phase is general and only concerns the iteration mechanism used to find several peers in a part of the P2P network. In the second step, when the nodes are found, a specific request is sent to ask for a particular service. The reputation checking must be done before the specific request for three reasons. Firstly, a peer can be a bridge and search contacts for other uncontrolled peers. Secondly, the real services are provided by the specific requests. Controlling the reputation at this point allows to revoke independently the different services. Finally, checking the reputation for Kademlia REQ would increase the overhead for no advantage. The figure 4 presents the running of a publication request and includes the reputation checking. The other requests (search, data download) follow the same scheme. However, inserting the revocation mechanism into the search function is not relevant for several reasons. Firstly, it is not a service through which a peer can damage the network. Then, searching is useless when the other services are inactive behind. Finally, it would also introduce overhead to the network and unnecessary delay for all users. + +## C. Implementation + +We have implemented the revocation mechanism in KAD. To do that, we have introduced different modifications in the KAD client: + +- our modified client can manage a new kind of information called ”Account”; + +- the associated requests search/store Account were written, which partially behave like existing requests on keywords, files or notes; + +- new functions were added in the UDPListener, where all network’s requests are processed. In fact, these functions do the service-oriented revocation, searching for the reputation and checking it. + +![](figure) + +![](figure) + +Fig. 5. Publication of accounts between modified KAD clients inside a tolerance zone + +- KadID and userID allocation were cheated to control the place of the peers in the DHT. + +We have tested that the reputation storage and retrieval and the revocation of services work fine on the modified peers. However, as our implementation defines new data types and messages to manage the accounts, we can just test our revocation mechanism on a few peers. Presently, as we test the mechanism with few resources, we have defined the KadID and UserID of modified peers to place them in the same tolerance zone. In this way, we are sure that the accounts can be stored (figure 5) when using the KAD publication mechanism. That is enough to verify the mechanism, but without the real number of replicated peers, performance measures would be wrong. That is why we are going to scale up our testbed on EmanicsLab to measure performances and compare the results with the evaluation presented in section + +V. + +## V. ANALYSIS AND DISCUSSIONS + +## A. Performances Evaluation + +The thesis [2] has led a performance evaluation of the KAD network which allows us to discuss some a priori performance results. The average delay needed to store information in the network is about 200 seconds. This time is needed to find ten peers (for the replication) with a KadID close to the hash of the information to store. This delay will occur the first time that a peer connects itself to the network and periodically later to maintain the account in the network despite the churn. The delay to retrieve the information fluctuates and depends on the replication. The more replication there is, the more robust the stored information is and the quicker it is retrieved. The information is retrieved linearly, so the more a peer waits, the more results are returned. A 100 seconds delay seems to be sufficient to retrieve enough information to guess the real reputation of a peer. This delay could seem huge because it appears prior to each service of the network, except the search as explained. But in fact, 100 seconds to bootstrap are not penalising, the publication process is entirely transparent for the user and 100 seconds preceding a download diff --git a/outputs/multi_column/0301cb032c92b9b49cbce64def4c292c277b_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0301cb032c92b9b49cbce64def4c292c277b_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..32fe302d7b6eedd679ebb7eba17364e05ce552f0 --- /dev/null +++ b/outputs/multi_column/0301cb032c92b9b49cbce64def4c292c277b_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +![](figure) + +## 1.54 μm photoluminescence enhancenment of Er3+-doped ZnO films containing nc-Ge: joint effect from Er3+ local environment changing and energy transfer of nc-Ge + +# RANRAN FAN, FEI LU,* AND KAIKAI LI + +School of Information Science and Engineering, Shandong University, Jinan 250100, China *Corresponding author: lufei@sdu.edu.cn + +Received 7 July 2017; revised 1 September 2017; accepted 11 September 2017; posted 15 September 2017 (Doc. ID 301875); published 16 October 2017 + +ZnO films containing Er and Ge nanocrystals (nc-Ge) were synthesized and their photoluminescence (PL) properties were studied. Visible and near-infrared PL intensities are found to be greatly increased in nc-Ge-containing film. Er-related 1.54 μm emission has been investigated under several excitation conditions upon different kinds of Ge, Er codoped ZnO thin films. 1.54 μm PL enhancement accompanied by the appearance of nc-Ge implies a significant correlation between nc-Ge and PL emission of Er3. The increased intensity of 1.54 μm in Ge:Er:ZnO film is considered to come from the joint effect of the local potential distortion around Er3 and the possible energy transfer from nc-Ge to Er3. + +© 2017 Chinese Laser Press + +OCIS codes: (160.2540) Fluorescent and luminescent materials; (160.4236) Nanomaterials; (160.5690) Rare-earth-doped materials; (310.6860) Thin films, optical properties; (310.1860) Deposition and fabrication. + +https://doi.org/10.1364/PRJ.5.000567 + +## 1. INTRODUCTION + +Doping erbium into semiconductors has attracted enormous interest in optical applications as Er-related 1.54 μm emission is within a wavelength range of minimum loss for silica optical fibers [1]. It has been reported that oxygen codoping and the use of wide-bandgap materials as the host material are effective to enhance the Er-related 1.54 μm emission [2,3]. ZnO is considered to be a promising candidate as a host material for Er doping because of being an oxide with a wide bandgap of about 3.37 eV [4,5]. However, the efficiency of 1.54 μm emission in ZnO:Er thin films has not yet been satisfied. It has been confirmed that through the addition of Si nanocrystals (nc-Si) into SiO2, strong Er3 photoluminescence (PL) at room temperature could be obtained [6–10]. Ge nanocrystals (nc-Ge) have many properties (wide size-dependent emission tunability, larger Bohr radius, etc.), which is superior to nc-Si [11]. The luminescence efficiency of Er3 may be enhanced by the introduction of nc-Ge through the change of local environment and recombination of photogenerated excitons in nanocrystals and subsequent energy transfer to Er3. Energy transfer from nc-Si to RE3 in a silica host has been intensively investigated in recent years. In comparison, few studies have been found on nc-Ge and Er3 in a ZnO host. In this paper, we deposit ZnO film with codoped Ge, Er in it by magnetron sputtering. Visible and near-infrared (NIR) PL intensities are found to be greatly increased in 600°C annealed Ge:Er:ZnO film compared to the as-deposited sample and the sample without Ge dopants. A 1.54 μm PL enhancement accompanied by the appearance of nc-Ge in an annealed sample implies a significant correlation between nc-Ge and Er3. The purpose of this work is to analyze how the nc-Ge participates in the PL enhancement. Our observed results suggest that the increased intensity of 1.54 μm in Ge:Er:ZnO film is the result of the joint effect of two factors: local distortion effect and the energy transfer from the nc-Ge participating in the efficient emission. A ZnO:Er2O3 (Er \(\sim0.6\) at. %) target with small pieces of 5 mm × 5 mm Ge chips was cosputtered by radio frequency magnetron sputtering onto Al2O3 substrates. In the current experiment, Ge concentration was fixed to be about 4% in volume fraction. The deposition was carried out in an oxygen and + +argon mixed gas atmosphere (Ar∕O2 2∕5), and the chamber pressure was maintained at a constant value of 0.7 Pa. After deposition, the Ge:Er:ZnO film thickness was measured to be about 400 nm. Postannealing of the film was performed for 20 min at temperature of 600°C in N2 atmosphere. As a comparison, the Ge:Er:ZnO film (Er \(\sim0.3\) at. %) and the Er:ZnO film (Er \(\sim0.6\) at. %) were also deposited under the same diff --git a/outputs/multi_column/031262e6346a8b7db19239800839b132c1ce_page_13_pg1_pg1_repeat1.md b/outputs/multi_column/031262e6346a8b7db19239800839b132c1ce_page_13_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0359e4d5fee6704c31157182b1a82ad63133faaa --- /dev/null +++ b/outputs/multi_column/031262e6346a8b7db19239800839b132c1ce_page_13_pg1_pg1_repeat1.md @@ -0,0 +1,53 @@ +![](figure) + +il-Legion of Mary, in-Neokatumenici, Two hearts u diversi gruppi kwazi impossibbli. oħra. + +billi jaħdem fuq l-aspett soċjali f ’dawn il-postijiet ta’ faqar kbir u problemi soċjali + +![](figure) + +![](figure) + +![](figure) + +# Kċejjen tal-Kommunita + +# Oqsma oħra + +Fil-post fejn kien ix-xogħol kien skars u n-nies l-iktar li kienu jaħdmu fil-kostruzzjoni bil-lava bajda. Benefiċċji soċjali ma jeżistux u għalhekk kien anki jorganizza kċejjen tal-kommunita bħal speċi ta’ Victory Kitchens ta’ żmien il-gwerra. L-ikel għal dawn il-kċejjen kien jirċevih minn istituzzjonijiet bħal Caritas u għaqdiet oħra mill-Amerika u mill-Ġermanja + +Mill-intervista sirt naf li Fr. Adami hu kittieb ukoll . Fil fatt hu kiteb numru ta’ kotba u booklets fuq materjal spiritwali fosthom , ktieb li jismu ‘Jesus dons the poncho’ li tfisser ‘Ġesu jilbes il-pancho’ , bl-għan ewlieni tiegħu li Ġesu jidentifika ruħu malfqar. Fr. Adami żied u qalli li dawn il-leaflets u l-booklets li hu kiteb tferrxu mal-Awstralja, u anki lil hinn, mill-Kanada saħansitra saċ-Cili’. + +# Xogħol ieħor ta’ Fejda + +F’dan il-post kien bena ukoll skola u wara orfanatrofju għal tfal bi bzonnijiet speċjali u fuq l-istess linja ta’ dik tas-Siġġiewi f ’Malta semmieha għall-Providenza. Kien irnexxielu jkisser il-mentalita’ u ħafna tfal b’nuqqasijiet fiżiċi u mentali li kienu dejjem magħluqa anki f ‘gaġġeġ għax il-ġenituri tagħhom kienu jistħu juruhom bdew joħorġu u jippruvaw jghixu ħajja kemm jista jkun normali. Fil-fatt f ’dik is-sitwazzjoni ta’ faqar il-ħajja diġa kienet għat- telgħa sew anki jekk tkun b’saħħtek u normali , aħseb u ara jekk ikollok xi difett fiżiku kemm tkun iktar ta’ piż għalik u anki għall-familja tiegħek. + +Meta staqsejtu jekk kellux għajnuna hu weġibni li filparroċċa kien hemm qassis ieħor Malti pero’ kien hemm żewġ qassisisn oħra pero’ kienu sagħtejn u nofs il-bogħod. + +# Ħelisha Hafif! + +Meta staqsejtu dwar xi anedottu minn ħafna li kellu hu semmieli fatt meta darba mar jiġri biex jilħaq karozza tallinja f ‘Arequipa u ma’ laħaqhiex bi ftit. Wara imbagħad sema’ li kienet tgerbet u mietu 17 il-ruħ. Hu kellu jkun magħhom u jqis dan il-fatt bħala miraklu. + +# Lura Malta u wara għal Down Under + +Fis- sena 1988 hu ntbagħat lura Malta fejn kien joqgħod Sant’Agata , r-Rabat. Sena wara reġa intbagħat fl-ewwel art tal-missjoni li ntbagħat fiha u reġa intbagħat l-Awstralja eżattament f ’Parkville, Melbourne. Din hija d-dar provinċjali u magħha hemm iċ-ċentru tal-Maltin ftit il-barra mil-Belt propja u hemm kont niltaqa’ miegħu. Fil-fatt jien meta kien imissni xogħol fl-uffiċċju tas-City kont nipparkja l-karozza fil-garaxx taċ-ċentru u mmur ix-xogħol bil-karozza tal-linja. + +Fr. Adami inħatar il-kappillan tal-Maltin, tat-Taljani u anki dawk li jitkellmu bl-Ispanjol. Kien ukoll ic-chaplain ta’ għaqda bl-isem ta’ ‘Helpers of the Precious Infants of God’ fejn dawn kienu jmorru jitolbu wara l-kliniċi li kienu jwettqu l-abort. + +Hu jwettaq ukoll xogħol pastorali mas-sud amerikani minn El Salvador. Hu ħadem ma ħafna gruppi Kattoliċi fosthom + +Minbarra l-kitba Fr. Adami kellu sehem f ’radjijiet talkommunita u hemm jagħmel omeliji kif ukoll intervisti ta’ natura spiritwali. Xi drabi kien jagħmel il-ħsieb tal-ġimgħa mal-magħruf xandar Malti Victor Aquilina. + +# Il-Birgu u l-Każin + +Fis-soltu mistoqsijiet konklussivi u ritwali tiegħi Fr.Adami wieġeb li l-Birgu għalkemm il-popolazzjoni naqset sew jara ħafna indafa , mhemmx bini modern, tħalla bħala belt medjevali, u jogħġbuh ferm festi li żviluppaw dan l-aħħar bħal Birgufest u Vittoriosa by Candlelight. + +Dwar il-każin hu qal li jsiru ħafna attivitajiet sbieħ li ma’ kienux isiru fi żmienu, bħal ikliet u ħarġiet familjari. + +# Issa u l-ġejjieni + +Bħalissa hu għadu jagħti s-sehem tiegħu f ’ Parkville, l-Awstralja u jiġi Malta għall-vaganzi speċjalment għallfesta ta’ San Lawrenz u għal Għid. + +Bħala l-aħħar domanda staqsejtu dwar il-futur tiegħu. Hu b’sinċerita weġibni li sakemm il-moħħ u s-saqajn jibqgħu tajbin jibqa fil-missjoni fl-Awstralja jew fejn jintbagħat mis-superjuri tiegħu. Wara l-ħsieb hu li jirtira u għalkemm ikun joqgħod id-dar tas-Soċjeta’ r-Rabat pero’ bi ħsiebu jgħin ħafna lill- Parrocca ta’ San Lawrenz. B’dan il-kliem sellimtlu filwaqt li f ’isimkom awgurajtlu għomor twil ta’ ħidma fil-missjoni imbagħad wara għal ħidma oħra f ’Malta u għala le ...fil-Birgu li tant iħobb. Żgur li aħna nkunu iktar minn kuntenti bih. Mhux hekk? + +![](figure) diff --git a/outputs/multi_column/031262e6346a8b7db19239800839b132c1ce_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/031262e6346a8b7db19239800839b132c1ce_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2b5fd8611f03280842f79003b8cf9ffc5731af1a --- /dev/null +++ b/outputs/multi_column/031262e6346a8b7db19239800839b132c1ce_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +![](figure) + +# Kompożituri famużi + +# Richard Wagner + +![](figure) + +#### jikteb Christopher Pisani + +![](figure) + +![](figure) + +F’dan l-artiklu li jmiss, iddeċidejt + +permezz tas-sinfonija numru 7 u n-numru 9. Wagner ħassu ispirat ferm minn Beethoven, tant li kien għamel transkrizzjoni tassinfonija numru 9 ta’ Beethoven. Fl-1831, Wagner daħal jistudja fl-Universita’ ta’ Leipzig, fejn ħa t-tagħlim tal-komposizzjoni taħt Theodor Weinlig. Dan Weinlig tant kemm kien impressjonat b’Wagner, li rrifjuta kull tip ta’ ħlas għal-lezzjonijiet li kien jgħatih u li kien irranġalu biex tiġi ppubblikata l-ewwel kompożizzjoni mużikali tiegħu, Piano Sonata in Si bemoll maggiore. Sena wara, Wagner kien ħareġ bil-komposiz-zjoni ta’ Sinfonija in Do maggiore, liema sinfonija smajt u li vera-ment għoġbitni u nirrakomanda lill-qarreja biex jisimgħu. Minn hawn, Wagner ma’ ħarisx lura u beda jikkomponi l-ewwel opra tiegħu Die Hochzeit (iż-żwieġ). + +li nbiddel ix-xenarju, l-ambjent, u n-nazzjonalita’ tal-kompożitur li jmiss. Richard Wagner, il-ġenju mużikali Ġermaniż li ta kontribut kbir għall-mużika operistika kif ukoll għal-litteratura. Ħa nibda billi nsemmi naqra kif ċertu esponenti prominenti fix-xena mużikali kienu jħarsu lejn Wagner. + +Peter Tchaikovsky kien qal li meta sema’ l-aħħar noti tal-opra Gotterdammerung, hu ħassu li kien qisu nħeles minn ħabs. Gioacchino Rossini, meta kien sema’ Lohengrin kien qal li ma tistax tiġġudika din lopra sempliċiment meta tismagħha l-ewwel darba, imma żgur li mhux se nismagħha t-tieni darba. Aktar riċenti, Woody Allen fil-film Manhatten Murder Mystery qal li hu ma jistax jisma ħafna mużika ta’ Wagner għax inkella jqanqal fih l-aptit li jinvadi l-Polonja. F’idejkhom biex tiddeċiedu jekk għandhomx raġun, kemm mill-ħajja tiegħu u kemm, forsi għal min jinteressah jisma naqra mużika tiegħu, mill-kompożizzjonijiet tiegħu. + +Fl-1833, ta’ 20 sena, wara li ħuh Albert kien irranġalu, daħal surmast tal-kor tat-teatru ta’ Wurzberg. Fl-istess sena, kien lesta l-opra tiegħu Die Feen (The Fairies). Interessanti ħafna li din l-opra indaqqet l-ewwel darba fl-1883 wara l-mewt ta’ Wagner stess. Fl-1834, Wagner laħaq surmast direttur tat-Teatru tal-Opra Magdeburg, fejn hemm kiteb l-opra Das Liebesverbot (The ban of love) li kienet ibbażata fuq ir-reċta ta’ Shakespeare Measure for Measure. Din indaqqet darba fl-1836 għaliex it-teatru kien falla finanzjarjament. Minn hemm, Wagner kien iltaqa’ ma’ Christine Wilhelmine Planer ‘’Minna’’, u li kien iżżewwiġha fl-24 ta’ Novembru 1836. Sena wara, Minna telqitu ma’ raġel ieħor, iżda wara li Wagner mar fir-Russja bħala direttur muzikali, permezz ta’ oħt Minna Amalie, kien reġa irranġa ma Minna fl-1838. Fl-1839, il-koppja Wagner akkumulat numru kbir ta’ djun, tant, li kellhom jemigraw lejn Riga, u wara lejn Pariġi. F’ dan il-vjaġġ abbord xini, f ’lejl ta’ maltemp, Wagner ġietu l-ispirazzjoni biex jikteb l-opra Der Fliegende Hollander (The flying Dutchman). Sakemm dam Pariġi, Wagner lesta din l-opra u anke Rienzi. Wara l-għajnuna ta’ Giacomo Meyerbeer, kompożitur ieħor famuż li xi darba jsib ix-xorti f ’din ir-rokna, Wagner esebixxa l-opra Rienzi b’suċċess kbir. Fl-1842, Wagner mar Dresden u hemm ikkompona opra oħra kbira, Tannhauser. F’dan iż-żmien, Wagner kien attiv + +Wagner twieled f ’Leipzig, nhar it-22 ta’ Mejju 1813. Kien id-disa’ wild ta’ Carl Freidrich Wagner (skrivan mal-pulizija ta’ Leipzig) u Johanna Rosine nee Paetz. Wara biss 6 xhur mit-twelid, missier Wagner miet, u ommu Johanna marret tgħix mal-ħabib ta’ Carl, Ludwig Geyer. Dan Geyer kien attur u skrittur, u x’uħud jaħsbu li kien hu l-verament missier. Li hu zgur hu li Johanna kienet issetiljat ma’ Geyer. Fl-awtobijografija Mein Leben, Wagner jiftakar li darba ħa sehem f ’reċta bħala anġlu. Fl-1820, Wagner daħal fl-iskola Pastor Wetzel ta’ Possendorf fejn kien qed jirċievi xi tagħlim tal-pjano, liema tagħlim sabu diffiċli ferm, tant li kien jippreferi li jdoqq bl-udit milli jaqra l-mużika. + +Wara l-mewt ta’ Ludwig Geyer, ħu Ludwig kien ħallaslu li jmur il-boarding school Kreuzschule. F’din l-eta’ tant tenera ta’ 9 snin, Wagner kien impressjonat ferm mill-Mużika Gotika ta’ Carl Maria Von Weber. Hawn hu kien kiteb lewwel biċċa xogħol tiegħu, it-traġedja li semma Leubald. Wara li beda l-iskola fl-1826, hu kien ferm influwenzat minn Shakespeare u Goethe. Fl-1827 familtu marret lura Leipzig, u beda jitgħallem l-armonija taħt Christian Gottlieb Muller. Sena wara, sema’ għall-ewwel darba lil Beethoven + +![](figure) diff --git a/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..417e77fb0d5baa64d4d987575fdfa8ba8792f26f --- /dev/null +++ b/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,35 @@ +# Modified DISTBIC algorithm for speaker change detection + +### Petra Zochová, Vlasta Radová + +### Department of Cybernetics University of West Bohemia, Pilsen, Czech Republic + +pzochova@kky.zcu.cz, radova@kky.zcu.cz + +### Abstract + +The paper deals with the problem of automatic speaker change detection. A metric-based algorithm, called MDISTBIC, which means Modified DISTBIC, is proposed in this paper. The algorithm originates from the DISTBIC algorithm and modifies it in order to reach a higher efficiency. Both the DISTBIC and the MDISTBIC methods are tested in a number of experiments. As the results show, the MDISTBIC algorithm is more efficient than the DISTBIC algorithm in a majority of tests. + +## 1. Introduction + +The aim of automatic speaker change detection is to extract homogeneous segments containing the longest possible utterances produced by a single speaker. Many efforts have been devoted to this problem in the last years, mainly due to the large number of possible applications, e.g.: + +- a reliable speaker change detection algorithm could be very helpful for annotators who manually annotate a large amount of speech data in order to organize an archive of audio documents (e.g. recordings of various sessions or meetings, broadcast news, etc.); + +- performance of a speech recognition system that recognizes conversations or news broadcasts could be improved, when a speaker change detection system would detect the change of the speaker and parameters of the speech recognition system would be adapted accordingly; + +- in speaker recognition systems it is supposed that the input speech belongs only to one speaker. It may cause problems in many real situations (e.g. in conversations or broadcast news), where the speech stream is continuous and there is no information about the beginning and ending of the speech segment of one speaker. A speaker change detection system could help to eliminate such problems. + +There are three main speaker change detection approaches [1], [2]. In the metric-based approach the speaker changes are determined as the moments in which a distance measure computed between two adjacent windows shifted along the speech signal reaches a local maximum. In the model-based approach it is assumed that a model of each speaker the voice of which is contained in an utterance has been trained before the speaker change detection algorithm starts. The speaker changes are then detected as the instants when it is necessary to change the speaker model in order it match the speech signal. The last approach is the decoder-guided approach. Here, the speaker changes are determined according to information provided by a speech recognition system which decodes the spoken audio stream at first (e.g. possible speaker changes are at every silence location). In this paper, we are interested in the metric-based approach, because it does not require any other information or things except the speech signal itself (i.e. neither speaker model, nor speech recognizer). We focus on the DISTBIC algorithm introduced in [3]. This algorithm is efficient in detecting speaker changes that are relatively close one another, however at the price that a lot of false speaker changes is detected. We will try to modify the algorithm in this paper and thereby to improve its efficiency. The paper is organized as follows: In Section 2 the DISTBIC algorithm is briefly described. Next, in Section 3 the modifications of the DISTBIC algorithm are introduced. Experiments are described and their results are presented in Section 4. Finally, a conclusion is given in Section 5. + +## 2. DISTBIC algorithm + +The DISTBIC algorithm is based on a two-step analysis [3]: the first pass uses a distance computation to determine the speaker changes candidates and the second pass uses Bayesian Information Criterion (BIC) to validate or discard these candidates. + +## 2.1. First step: detection of speaker change candidate points + +The first step relies on a distance-based segmentation defined from the likelihoods of adjacent windows. In each window, the data are assumed to result from a single multi-dimensional Gaussian process. The question is, whether the data from the two adjacent windows together fit better with a single multidimensional Gaussian or whether a two-window representation justifies the data better. In order to answer this question, the Kullback-Leibler distance can be used for example. A symmetric Kullback-Leibler distance KL2 between a vector \(X\) coming from the multi-dimensional Gaussian process \(N(\mu_{X},\Sigma_{X})\) and a vector \(Y\) resulting from the multidimensional Gaussian process \(N(\mu_{Y},\Sigma_{Y})\) can be computed as + +\[\begin{aligned} KL2(X,Y)&= \frac{1}{2} (\mu_{Y}-\mu_{X})^{T}(\Sigma_{X}^{-1}+\Sigma_{Y}^{-1})(\mu_{Y}-\mu_{X})+ \\ +_{+} \frac{1}{\frac{2_{1}}{2}} t_{t}r_{r}\bigg(\left((_{(}\Sigma_{\Sigma}^{\frac{1}{-X_{X^{2}}}} \frac{\Sigma_{1}}{2} \Sigma^{Y- \frac{1}{\frac{12}{Y^{2}}}})^{)}(^{(}\Sigma^{\Sigma_{\frac{1}{2}}^{\frac{1}{-_{X}X^{2}}}\Sigma}\Sigma^{-_{Y} \frac{1}{\frac{12}{Y^{2}}}})^{)_{T}^{T}}\right)-^{+}d, \end{aligned}\] + +where tr denotes the trace of a matrix, and \(d\) is the dimension of the vectors \(X\text{and}Y\) . The KL2 distance is computed for two adjacent windows \(W_{1}\text{and}W_{2}\) of the same size (2 s) shifted by a fixed step diff --git a/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0a826f5a4c80c302ba246d8d3fa940727fee7d22 --- /dev/null +++ b/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,49 @@ +(100 ms) along the whole speech signal. This process results in a graph of distances with respect to time. The graph is smoothed by a low-pass filtering operation, and then all the significant local maxima are searched because they represent potential speaker change points. A local maximum is regarded as significant when the differences between its value and those of the minima surrounding it are above a certain threshold, and when there is no higher local maximum in its vicinity. Thus, the local maximum has to fulfill the following condition to be significant: + +\[\begin{aligned} |\max-\min_{l}|&>\alpha\sigma \\ \text{and} \\ |\max-\min_{r}|&>\alpha\sigma, \end{aligned}\] (2) + +where \(\alpha\) is a real number, \(\sigma\) is the standard deviation of the distances along the plot, and minl and minr are the left and the right minima, respectively, around the peak max. + +### 2.2. Second step: BIC refinement + +A \(\Delta BIC\) value is computed for each potential speaker change point detected in the first step to validate or discard this point. The \(\Delta BIC\) value is given by [3] + +\[\Delta BIC=-R+\lambda P,\] (3) + +where + +\[R= \frac{N}{2} \log|\Sigma|- \frac{N_{1}}{2} \log|\Sigma_{1}|- \frac{N_{2}}{2} \log|\Sigma_{2}|,(4)\] + +\(\lambda\) is a penalty factor which has to be experimentally tuned in order to reduce the number of false alarms without increasing the number of missed detections, + +\[P= \frac{1}{2} \left(d+ \frac{1}{2} d(d+1)\right)\log N,\] (5) + +\(N_{1}\text{and}\Sigma_{1}\) are the number and the covariance matrix of the feature vectors in the window \(W_{1}\), respectively, \(N_{2}\text{and}\Sigma_{2}\) are the number and the covariance matrix of the feature vectors in the window \(W_{2}\), respectively, \(N=N_{1}+N_{2},\Sigma\) is the covariance matrix of the feature vectors of both windows together, and \(d\) is the dimension of the feature vectors. A potential speaker change point is regarded as a true speaker change if the \(\Delta BIC\) value for this point is negative. + +## 3. Modified DISTBIC algorithm + +The DISTBIC algorithm allows to obtain good speaker change detection results, nonetheless it has some weak points. We have focused on these points and suggest some improvements of the algorithm in order to obtain even better results. The improvements are specified in next subsections. + +### 3.1. Silence and breathing elimination + +Silence and breathing may cause a lot of false alarms in speaker change detection tasks. Therefore we used a simple but efficient silence detector before the speaker change detection process. The speech signal was divided into segments the length of which was 10 ms. Short-time energy and the number of zero crossings [4] were computed for each segment. If both the short-time energy and the number of zero crossings were lower than experimentally derived thresholds, the segment was regarded as containing silence and was temporarily eliminated from the utterance. + +![](figure) + +![](figure) + +Figure 1: True speaker change points causing troubles (marked with a circle) in the condition (2). + +Sometimes short sections with a high energy can occur in silent parts of the utterance. Such sections can be caused for example by the speaker breathing. The high energy impels the silence detector to regard these sections as speech. In order to overcome this problem, we implemented a clustering algorithm: if a part of a speech signal shorter than 645 ms was surrounded by silent segments, this part was also regarded as silence. On the contrary, if there was a silent segment shorter than 250 ms between two segments containing speech, this segment was regarded as containing speech. + +### 3.2. Speaker change candidate detection + +Equally as in Section 2.1, the potential speaker change points were detected on the smoothed graph of the symmetric Kullback-Leibler distance. However, the condition (2) necessary to detect the potential speaker change points was changed. The reason for the change was the fact, that the condition (2) did not allow to detect some local maxima of the graph as the potential speaker change points. The problems were caused mainly by the maxima that were rather near each other, so that the minimum between them was too high to satisfy the condition (2). An example of such a kind of peaks is shown in Figure 1. For that reason the conjunction in (2) was substituted with the disjunction, i.e. a local maximum was regarded as a potential speaker change point if it satisfied the condition + +\[\begin{aligned} |\max-\min_{l}|&>\alpha\sigma \\ or \\ |\max-\min_{r}|&>\alpha\sigma, \end{aligned}\] (6) + +where \(\alpha,\sigma\), minl, minr, and max have the same meaning as before. In order to avoid the situation that two different maxima belonging in fact to one true speaker change would be detected as two potential speaker change points, we required a minimal distance between two maxima: if two maxima were closer than 0.5 s, the lowest one was discarded. This condition protects the algorithm against false alarms. + +### 3.3. Speaker change position location + +Having detected the potential speaker change points, we used the \(\Delta BIC\) value (3) to discard or validate the points similarly diff --git a/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1ada3fc6f0687b37a237f383b4cda186446ce42c --- /dev/null +++ b/outputs/multi_column/031a888e402c82517f213222ae97147dd7dc_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,47 @@ +![](figure) + +Figure 2: Illustration of the correspondence between the peak on the smoothed distance graph (solid line) and the peaks on the unsmoothed distance graph (dashed line). + +like in Section 2.2. However, more than one local peak on the unsmoothed distance graph may correspond to the speaker change point detected on the smoothed graph (see Figure 2 for illustration). For that reason, we computed the \(\Delta BIC\) value for all local peaks on the unsmoothed graph that correspond to the peak validated as the speaker change on the smoothed graph, and the local peak with the lowest \(\Delta BIC\) value was chosen as the true speaker change. + +### 3.4. Time alignment + +Silent parts temporarily eliminated from the speech signal in Section 3.1 have to be inserted back into the utterance now, and the points of the speaker changes have to be aligned accordingly. In addition, if a detected speaker change was close (less than 0.2 s) to a silent part, it was moved into the centre of the silent part. + +## 4. Experiments and results + +The purpose of the experiments was to compare the performance of the DISTBIC algorithm and the Modified DISTBIC (MDISTBIC) algorithm. Both of these algorithms were tested in several experiments, where audio records of TV news, radio news and radio discussions were automatically segmented with respect to the speaker changes. + +- The radio news test set consisted of 8 records containing news broadcasted by the Czech radio station Český rozhlas 2 – Praha. The length of each record was about 10 minutes, each record contained about 23 speaker changes on average. Speakers in the records did not speak simultaneously and the interval between two consecutive speaker changes was quite long. + +- The TV news test set contained 7 records of newscasts of different Czech TV channels. The length of the records ranged from 11 to 20 minutes, each record contained about 94 speaker changes on average. Similarly as in the radio news, the speakers did not speak simultaneously. However, unlike the radio news, about 9% of speaker changes were quite close (less than 2 s). + +- The radio discussions test set contained 9 records of the programme Radiofórum broadcasted by the Czech radio station Český rozhlas 1 – Radiožurnál. The length of each record was approximately 30 minutes, each record contained about 105 speaker changes on average. Approximately one third of the changes occurred very soon after the previous change (i.e. the changes were closer than 2 seconds). In addition, the speakers spoke often simultaneously. + +Two types of errors could happen during the segmentation. A false alarm (FA) occurred when a speaker change was detected, although it did not exist. On the contrary, a missed detection (MD) occurred when the algorithm did not detect an existing speaker change. If we know the number of FA and MD for a record, we can determine the accuracy and the false alarm rate (FAR) that ware achieved for the record using a segmentation algorithm. The accuracy is defined as + +\[\text{Accuracy}=100\times\] (7) + +\[\times \frac{numberoftruespeakerchanges-numberofMD}{numberoftruespeakerchanges} [\%],\] + +and the FAR is determined according to the formula + +\[\text{FAR}=100\times\] (8) + +\[\times \frac{numberofFA}{numberoftruespeakerchanges+numberofFA} [\%].\] + +The accuracy and the false alarm rates achieved for records from the above mentioned test sets using both the DISTBIC and the MDISTBIC algorithms are given in Tables 1, 2, and 3 in detail. It can be found out after an inspection of the results, that the MDISTBIC algorithm gives better results (i.e. a higher accuracy and a lower FAR) in a majority of the tests. It outperforms the DISTBIC algorithm both for the radio news where there were long intervals between the speaker changes and for the radio discussions where the speaker changes were relatively very close one another and the speakers often spoke simultaneously. This can be seen also from the Figures 3, 4, and 5, where the average values of the accuracy and false alarm rates for each of the 3 test sets are lucidly presented. In order to provide all information about the experiments we should also say that + +- the sample frequency was 8 kHz and 12 mel-frequency cepstral coefficients were used as feature vectors for the representation of the speech signal, + +## • a Gaussian function + +\[h(t)=\exp(- \frac{t^{2}}{2\tau^{2}} ),\] (9) + +where \(\tau\) was set to 5, was used for the smoothing of the distance graph, and + +\(\bullet\lambda\text{and}\alpha\) in (3) and (6), respectively, were tuned separately for each algorithm and test set so that none of the methods was privileged to the other. + +## 5. Conclusion + +The Modified DISTBIC (MDISTBIC) algorithm for automatic speaker change detection in audio records has been introduced in this paper. The algorithm has been tested in a number of tests, and the results have been compared with the results achieved using the original DISTBIC algorithm. It follows from the results diff --git a/outputs/multi_column/0353b31c0381513a685be1878f8fad7d01d6_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/0353b31c0381513a685be1878f8fad7d01d6_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..88c920144b42f65960ae8e0433a7303ecb3702cd --- /dev/null +++ b/outputs/multi_column/0353b31c0381513a685be1878f8fad7d01d6_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,79 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +\[\pi(t_w) = \sum_{w \in \mathcal{G}} t_w w + \sum_{i+j \leq 2\bar{P}} (z_1^{-1} z_2^{-1} s, z^i z^j)\] + +\[\quad - \sum_{w \in \mathcal{G} \cap \Xi}_{(i,j)} t_w \xi_1^i \xi_2^j.\] + +\[\quad (12)\] + +2) Consider the following sets in \(K\) : + +\[T_q = \{(t_w): (t_w) \in K^{\mathcal{G}}, \text{rank } \mathcal{H}_{\bar{P} \times \bar{P}}(\pi(t_w)) \leq q\} \quad q \leq m\] + +\[V_q = \{(t_w): (t_w) \in K^{\mathcal{G}}, \text{rank } \mathcal{H}_{\bar{P} \times (\bar{P}+1)}(\pi(t_w)) \leq q\} \quad q \leq m\] + +\[U_q = \{(t_w): (t_w) \in K^{\mathcal{G}}, \text{rank } \mathcal{H}_{(\bar{P}+1) \times \bar{P}}(\pi(t_w)) \leq q\} \quad q \leq m.\] + +\[\quad (13)\] + +Each condition on the rank of matrices in (13) in equivalent to a number of conditions on the minors of order \(q + 1\) and is expressed by a system of algebraic equations in the parameters \(t_w\) , \(w \in \mathcal{G}\) . Thus, \(T_q\) , \(V_q\) , and \(U_q\) are algebraic varieties in \(K^{\mathcal{G}}\) . + +3) Evaluate the smallest value of the index \(q\) such that + +\[\mathfrak{W}_q \triangleq (T_q - T_{q-1}) \cap (V_q - V_{q-1}) \cap (U_q - U_{q-1}) \neq \emptyset. \quad (14)\] + +Let \(\bar{m}\) denote this value. Then \((t_w) \in \mathfrak{W}_{\bar{m}} = (V_{\bar{m}} \cap U_{\bar{m}}) \cap (T_{\bar{m}} - T_{\bar{m}-1})\) if and only if \(\pi(t_w)\) belongs to \(\mathcal{P}\) and has minimal partial partial representation. In fact, \(\bar{m}\) is the smallest value of \(q\) for which the equations chain + +\[\text{rank } \mathcal{H}_{\bar{P} \times \bar{P}}(\pi(t_w)) = \text{rank } \mathcal{H}_{\bar{P} \times (\bar{P}+1)}(\pi(t_w))\] + +\[= \text{rank } \mathcal{H}_{(\bar{P}+1) \times \bar{P}}(\pi(t_w)) = q\] + +admits a \((t_w)\) solution. + +As obvious consequence, minimal partial representation have dimension \(\bar{m}\) . + +4) Use (12) for constructing polynomials in \(\mathcal{P}\) which have minimal partial representations. + +Clearly, \(\mathfrak{W}\) is constituted by all noncommutative rational power series of rank \(\bar{m}\) which extend the polynomials obtained by the above steps. + +Once we obtained the set \(\mathfrak{W}\) , we can use the generalized Ho algorithm for getting minimal partial representations. The set of these representations gives, modulo similarity transformations, all minimal realizations of \(\mathcal{S}\) . + +Clearly, points 2) and 3) are the most difficult to be implemented because they involve the solution of several nonlinear algebraic equations. On the other hand, the necessity of introducing nonlinear algorithms is intrinsic to the problem as the dimension of minimal realizations depends on the ground field. + +V. CONCLUSIONS + +In this paper by pursuing the idea of introducing a state space model of two-dimensional filters, the realization problem has been further investigated along the directions outlined in previous works [1], [2]. + +The class of realizations introduced in this paper is characterized by a local state updating equation of the following form: + +\[x(h+1, k+1) = A_1 x(h+1, k) + A_2 x(h, k+1)\] + +\[\quad + Bu(h, k).\] + +The minimality of the realizations is not guaranteed by reachability and observability. In general, the dimension of minimal realizations depends on the field \(K\) and does not coincide with the rank of \(\mathcal{H}(s)\) . Nevertheless, we can associate the commutative series \(s\) with noncommutative recognizable power series whose representations provide all the realizations of \(s\) . Hence, the problem of determining minimal realizations of \(s\) can be approached looking for minimal representations of noncommutative power series. + +REFERENCES + +[1] E. Fornasini and G. Marchesini, "Algebraic realization theory of two dimensional filters," in Proc. Variable Structure Systems with Application to Economics and Biology Seminar , Portland, May 1974; also in Springer Lecture Notes in Econ. and Math. Syst. , no. 111, 1975. [2] —, "State-space realization theory of two-dimensional filters," IEEE Trans. Automat. Contr. , vol. AC-21, Aug. 1976. [3] —, "Reachability and observability in realization theory of spatial filters," in Proc. 5th ICEE , Oct. 1975. [4] —, "Two-dimensional filters: New aspects of the realization theory," in Proc. IEEE 3rd Int. Conf. on Pattern Recognition , Coronado, 1976, pp. 716-722. [5] E. D. Sontag, "First order equations for multidimensional filters," IEEE Trans. Acoust., Speech, Signal Processing , vol. ASSP-26, pp. 480-482, Oct. 1978. [6] M. Fliess, "Séries réconnaissable, rationnelles et algébriques," Bull. Sci. Math , 2nd series, vol. 94, pp. 231-39, 1970. [7] —, "Matrices de Hankel," J. Math. Pures Appl. , vol. 53, pp. 197-222, 1974. [8] B. L. Ho, "Effective construction of linear state-variable models from input/output functions," in Proc. 3rd Allerton Conf. on Circuit and System Theory , 1965, pp. 449-459. [9] E. Fornasini, "On the relevance of noncommutative formal power series in spatial filters realization," IEEE Trans. Circuits Syst. , vol. CAS-25, pp. 290-299, May 1978. [10] A. J. Tether, "Construction of minimal linear state-variable models from finite input/output data," IEEE Trans. Automat. Contr. , vol. AC-15, pp. 427-436, Aug. 1970. + +The Approximation of Image Blur Restoration Filters by Finite Impulse Responses + +R. W. SCHUTTEN AND G. F. VERMEIJ + +Abstract—Image blur can often be modeled by a linear spatially invariant, symmetric point spread function. For this class of functions, several restoration filters are known in the literature. + +The approximation of their frequency transfer functions (ftt's) by the ftt's of small finite impulse response (FIR) filters has been studied. Accurate approximations will be possible by \(9 \times 9\) FIR's with 8-bit elements if the approximation is done in a weighted MMSE sense, and if the truncation of the element values will be carried out such that the errors are small. A heuristic truncation algorithm MINIM will be described. An example of restoration by a \(9 \times 9\) FIR will be shown. + +Index Terms—Approximation, finite impulse response, finite register length, image blur, restoration filter. + +I. INTRODUCTION + +In the literature on image processing [1]-[3] a number of restoration filters are known, which can be applied in the case of spatially invariant image blurring. In general, these filters are implemented by means of the discrete Fourier transform (DFT), with help of the FFT algorithm. These filters, however, are operational only for static images as a consequence of the computational complexity. + +Manuscript received March 22, 1978; revised June 20, 1979. + +R. W. Schutten was with the Department of Electrical Engineering, Group on Measurement Science and Instrumentation, Twente University of Technology, Enschede, The Netherlands. He is now with the Philips Research Laboratories, Eindhoven, The Netherlands. + +G. F. Vermeij is with the Department of Electrical Engineering, Group on Measurement Science and Instrumentation, Twente University of Technology, Enschede, The Netherlands. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/038650c9dfd95e7495d0c4d301d9dcca735a_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/038650c9dfd95e7495d0c4d301d9dcca735a_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fd03749e1ad1af3c252326761f77237b4c5a01bd --- /dev/null +++ b/outputs/multi_column/038650c9dfd95e7495d0c4d301d9dcca735a_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,57 @@ +# Allen E. Paulson College of Engineering Computing + +The Allen E. Paulson College of Engineering and Computing at Georgia Southern University offers both undergraduate and graduate degree programs. At the undergraduate level, the college offers the Bachelor of Science degree programs in Civil Engineering, Computer Science, Construction Management, Electrical Engineering, Computer Engineering, Information Technology, Manufacturing Engineering and Mechanical Engineering. Computer Science and Information Technology are offered on both the Statesboro and Armstrong campuses. The first two years of the Mechanical Engineering program is offered on the Armstrong campus and students must transition to the Statesboro campus to complete the ME degree. The Regents' Engineering Pathway (REP) Program, available on both the Armstrong and Statesboro campuses, is offered as an option for students to complete the first two years of their engineering curriculum at designated Georgia colleges and then transfer to Georgia Southern (or another engineering school in Georgia) based on the availability of a particular major, to complete their BS degree in engineering. The WebBSIT is offered entirely online. At the graduate level, the college offers Master of Science degree programs in Engineering and Computer Science on the Statesboro campus. The Master of Science in Computer Science (MSCS) is offered as a hybrid program with a combination of both online and face to face courses. The College also offers two graduate certificates in Engineering & Manufacturing Management, and Occupational Safety & Environmental Compliance on the Statesboro campus as well. + +# Vision + +The College of Engineering and Computing will be a nationally recognized leader in engineering, computer science, and information technology in the areas of student-centric and application-based teaching, research, and service. + +# Mission + +The College of Engineering and Computing will maintain a dynamic and evolutionary environment of excellence in teaching, research, and service in which students, faculty and staff can achieve their professional goals. In these endeavors, the College will foster student-centric professional learning experiences utilizing advanced technologies that are applied with state-of-the-art equipment, inspire innovation and invention, encourage sustainability, and technically and economically enrich our communities and societies. + +# College Structure + +- Department of Civil Engineering and Construction Management (http://catalog.georgiasouthern.edu/undergraduate/allen-paulson-engineering-computing/civil-engineering-construction-management) + +- Department of Computer Science (http://catalog.georgiasouthern.edu/ undergraduate/allen-paulson-engineering-computing/computer-science) + +- Department of Electrical and Computer Engineering (http:// catalog.georgiasouthern.edu/undergraduate/allen-paulson-engineering-computing/electrical-computer-engineering) + +- Department of Information Technology (http:// catalog.georgiasouthern.edu/undergraduate/allen-paulson-engineering-computing/information-technology) + +- Department of Manufacturing Engineering (http:// catalog.georgiasouthern.edu/undergraduate/allen-paulson-engineering-computing/manufacturing-engineering) + +- Department of Mechanical Engineering (http:// catalog.georgiasouthern.edu/undergraduate/allen-paulson-engineering-computing/mechanical-engineering) + +- REPP - Regents' Engineering Pathway Program (http:// catalog.georgiasouthern.edu/undergraduate/allen-paulson-engineering-computing/regents-engineering-pathway-program) + +#### Experiential Learning Opportunities Internships + +Internship opportunities are available for all undergraduate programs in the Allen E. Paulson College of Engineering and Computing and are required for students majoring in Construction Management and Information Technology. Internships are supervised experiential learning programs, designed to allow students an opportunity to receive practical experience in their chosen field of study. Students should contact the Associate Dean for Students & Curriculum for further information. + +##### Cooperative Education + +Co-ops allow students the opportunity to gain work experience related to their academic major while earning a salary. To participate in a cooperative education opportunity, a student must have completed at least 30 semester hours of instruction, have a grade point average of at least 2.5, and be willing to participate in a minimum of two alternating co-op work semesters. Work responsibilities and salaries are determined by the employer. Students should contact the Associate Dean for Students & Curriculum for further information. + +##### Undergraduate Research + +Involving undergraduate students in applied, hands-on research activities and projects is a primary focus of the College. College administration and faculty work diligently to provide students with abundant opportunities to engage in research under faculty supervision. Examples of each department's current areas of research are included in the department brochures and web pages. The Dean’s Office and corporate sponsors funds student-led research projects which are showcased in the annual Student Research Symposium. + +## Programs + +## Majors + +- Civil Engineering B.S.C.E. (http://catalog.georgiasouthern.edu/ undergraduate/allen-paulson-engineering-computing/civil-engineering-construction-management/civil-engineering-bsce) + +- Computer Engineering B.S.Cp.E. (http://catalog.georgiasouthern.edu/ undergraduate/allen-paulson-engineering-computing/electrical-computer-engineering/computer-engineering-bscpe) + +- Computer Science B.S. (http://catalog.georgiasouthern.edu/ undergraduate/allen-paulson-engineering-computing/computer-science/computer-science-bs) + +- Construction Engineering B.S.Con.E. (http:// catalog.georgiasouthern.edu/undergraduate/allen-paulson-engineering-computing/civil-engineering-construction-management/ construction-engineering-bscone) + +- Construction Management B.S.Cons. (http:// catalog.georgiasouthern.edu/undergraduate/allen-paulson-engineering-computing/civil-engineering-construction-management/ construction-bscons) + +- Electrical Engineering B.S.E.E. (http://catalog.georgiasouthern.edu/ undergraduate/allen-paulson-engineering-computing/electrical-computer-engineering/electrical-engineering-bsee) + +- Information Technology B.S.I.T (Concentration in Data Science) (http://catalog.georgiasouthern.edu/undergraduate/allen-paulson- diff --git a/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_18_pg1_pg1_repeat1.md b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_18_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f1ccf010027b15138f11841882eef124c79469a7 --- /dev/null +++ b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_18_pg1_pg1_repeat1.md @@ -0,0 +1,19 @@ +# FROM THE LOGBOOK: + +![](figure) + +# Becoming by Jim Trusty A Test Pilot...Once Every Year + +![](figure) + +Is it time for an annual inspection? Ever dream of being a Test Pilot? The first flight after the annual inspection of your airplane can either be totally uneventful or a very busy flight. I have known and trusted my mechanic for years, and he seldom misses anything. This is good because live, happy, and satisfied pilot/customers can recommend you to others and then return the next time to spend more money. Even so, you should always expect the worst and be prepared. Just think about this statement while I use my case as an example. Four strangers to my aircraft checked, filled, turned, tightened, touched, replaced, repaired, removed, looked, pondered, and evaluated over 100 items on a factory inspection checklist and then complied with the latest Airworthiness Directives from problems encountered in the last year or so with its make and model. Two of these young men were A&P trainees with absolutely no experience as mechanics. Some things that fellow pilots have experienced over the years as they left from the annual include, but are not limited to, the following: engine oil not refilled, rags left in gear door wells, fuses pulled, battery disconnected, spark plugs left out on one side, screws not replaced in cowling cover, brakes not bled, fuel turned off, hydraulic fluid not refilled, gear handle in the UP position while the gear is actually DOWN, and tools left on the engine, in the floor under the cabin, and under the seats and carpets. I might also add that no pilots were injured, crashed, or died because of the foregoing list of mistakes. And in testimony to the hard work that our mechanics do, I really feel that it is impossible to do what they do and combine that with what we do to the airplane during the year and not have an adventure occasionally. But we should be apprehensive...RIGHT? If they tell you about a problem area that required parts, time, and research and that they think the problem was caught just in time, then you have been forewarned to watch that area much more closely than you normally would. Some would argue that the A&P should be required to fly the aircraft before they release it back to the owner and even others would say that makes as much sense as having the owner participate in the actual work of doing the annual inspection. NO THANKS! As a flight instructor who does an awful lot of proficiency training, flight reviews, and transition work on complex/high performance aircraft, I have found that pilots who DO NOT fly on a regular basis are generally not as ready as they should be to react to an “unexpected happening” in the air. When I review emergency procedures (such as gear, radio, and vacuum failures and add fuel transfer mistakes), I find that most pilots are not as well versed in recovery procedures as they should be. + +This is clearly the fault of the pilot. We get a little complacent and start comparing flying with driving and mistakenly think if something goes wrong that we will have plenty of time to just pull over to the side of the sky and call someone to come fix it. WRONG! I never cease to be amazed when reading accident reports from the NTSB and others just how much of a role pilots often play in what happened and how with just a normal amount of specific training the entire thing could have turned out differently. Careful selection of a mechanic based on known skill levels for your particular aircraft will not keep something from happening, but it certainly couldn’t hurt. Do not make the mistake many pilots make of mechanic selection based solely on the cost of the annual. This is certainly inviting trouble. Bring a squawk list with you and explain the items included. Work with them, especially since it is to your benefit. The list of people hurt and/or killed in aviation accidents does not have to include your name. You really have a choice in this decision. Is it time for an annual inspection? Ever dream of being a Test Pilot? Let’s be careful up there. + +### 3 + +![](figure) + +Jim Trusty was the FAA/Aviation Industry National Flight Instructor of the Year (1997) and still works full-time as a pilot/flight instructor at MQY in Tennessee. + +![](figure) diff --git a/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_19_pg1_pg1_repeat1.md b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_19_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f32fe5185933cc9e1adde3359608836c7a937679 --- /dev/null +++ b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_19_pg1_pg1_repeat1.md @@ -0,0 +1,57 @@ +![](figure) + +MEDICALstuff +Living and Filing "Over Greed"[^inferred] + +![](figure) + +MEDICALstuff +Living and Filing "Over Greed"[^inferred] + +# Living and Flying “Over Gross” How to Jettison Fat + +‘The time has come,’ the Walrus said, ‘to talk of many things...’ —From Lewis Carroll’s The Walrus and the Carpenter + +This just might be the time to decide to lose some weight, especially since summer is coming, and bathing suits and shorts show it like it is. There is no problem with motivation. Take just about any three people you see: The odds are that one needs to lose weight and one is obese. + +#### Lifting the Fog + +Motivation books are really worthless because anyone who buys one is already motivated. The problem is self-discipline. The search for the easy fix leads to myriad diets and resolutions to lose weight. Diet-book writers dance on the table and promote erroneous and dangerous fads that sell, and sell and sell. Millions spend millions of dollars to join the dog-and-pony shows in a burst of enthusiasm and do lose weight fast. But, the point is not to lose weight but to lose fat. You can easily lose twenty pounds of weight in two weeks. First goes the glycogen (sugar) in your liver, then goes water, and finally muscle protein is burned. The immutable law of metabolism is that 3,500 calories must be burned to lose a pound of fat. All miracle diets—when studied carefully—are actually low-calorie diets. Eventually, after a few months or so you either become sick of the diet, or become sick physiologically. “I can’t lose weight.” “I have a very low metabolism.” “It’s hereditary— by Glenn R. Stoutt, Jr., M.D. + +![](figure) + +everyone in my family is fat.” “My thyroid is not working right.” “I have cellulite all over.” These are excuses, not reasons. Think of this: If the person dearest to you would die if you did not lose fat (in a reasonable time) it’s inconceivable that you would not do so. Self-disci-pline would then take care of the fat. So, the argument that you cannot lose fat is not valid. + +#### Diets + +A psychological barrier with most diets is that they emphasize what you cannot eat—they accentuate the negative. Here is a positive, foolproof way to eat properly and still never go hungry. No one should ever go on a diet. Instead, learn to eat properly. Stay on this list of foods until you get to your desired weight. Plan on losing a pound a week (see table, on page 18). Until you have attained your goal, if a food is on this list, eat it. If not, don’t. There is absolutely no way to avoid losing fat if you eat only these foods. And, you will not lose an ounce of muscle. Forget that there is such a word as “diet.” + +#### Scales + +Stop weighing yourself. How do your clothes fit? How do you look unclothed in the mirror? Scales tell nothing but how much you weigh. + +#### Patience + +Be patient. Losing 50 pounds of fat might take as much as a year. But, it probably took over a year to accumulate the pounds. New clothes do not become snug or tight in just a few months. If just your pants or skirt are too tight, even a few weeks of proper eating will accomplish wonders—for your appearance and mood. + +#### Snacks + +A snack at mid-morning, mid-af-ternoon, and late evening will keep any hunger away. Six small meals are always much better than the three regular ones we are accustomed to. + +#### Meats + +Choose one: fish, chicken, turkey, or beef once a day. Not all four. + +#### Exercise + +Regular exercise is absolutely necessary. A rule of thumb for fat loss: about 80% from diet and 20% from exercise. Both are essential. + +#### Balance + +When you attain your desired body proportions (not just weight), relax a bit down to the Rule of 80/20. Eat in moderation about 80 percent of the time, and enjoy what you like to eat (again, reasonably) the other 20 percent of the time. You don’t have to give up the pleasures of foods you really like. + +#### Moderate + +Self-discipline is the key to attaining and keeping your optimum body fat all your life. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_20_pg1_pg1_repeat1.md b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_20_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4a3efb40c13137721b3b8c5d5aede993d9daeab2 --- /dev/null +++ b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_20_pg1_pg1_repeat1.md @@ -0,0 +1,55 @@ +No use being a zealot. A couple of teaspoons of sugar on your morning oatmeal or cereal, and beans or greens cooked in a small amount of bacon or ham won’t wreck your routine. Eat just about anything you want or crave (reasonable amounts) for one meal a week. Life without pizza on the weekend would be unendurable for some people. One alcoholic beverage (a beer, glass of wine, or a drink) once a week at mealtime is fine. Any eating plan will fail if it is too rigid. + +###### Size + +You have nothing to lose but fat, and some sizes in your belt and clothes. + +###### Timing + +Is this your time for blubber elimination? King Solomon wrote of the proper time for everything under the sun: a time to sow and a time to reap, a time to live and a time to die—and so on. No one will decide to lose fat (or stop being an alcoholic) until the proper time is reached—for him or her. For people who are tortured by being overweight, the time just might be right now. Yours for good health and safe flying + +Dr. Stoutt is a partner in the Springs Pediatrics and Aviation Medicine Clinic, Louisville, Ky., and he has been an active AME since 1960. No longer an active pilot, he holds a commercial pilot’s certificate with instrument, multi-engine, and CFI ratings. + +Note: This article appeared in the Summer 2002 Federal Air Surgeon’s Medical Bulletin. The views and recommendations made in this article are those of the author and not necessarily those of the Federal Aviation Administration. + +# The Best of + +## the Best Foods + +## Feature them in your foolproof eating plan + +#### Food Guide Pyramid + +###### A Guide to Daily Food Choices + +All-bran cereals Apples Asparagus Bananas Beans Beef (lean cut) 4 oz. per day Beets Berries Bread (whole-grain) 1-3 slices a day Broccoli Brussels sprouts Buttermilk (low-fat) Cabbage Cantaloupe Cauliflower Celery Chicken breast (no skin, broiled or baked) 4 oz. per day Collard greens Condiments (just about any that don’t have a lot of fat, sugar, or salt) Cottage cheese (low-fat or no-fat) Cream (fat-free sour cream) Cucumbers Eggs 1-2 a day if your cholesterol is OK. (hard-boiled or poached) Fish (cod is great)-not fried! Kale Lettuce Margarine (no fat) Milk (skim, no-fat) Mushrooms Mustard greens Nuts (handful a day at most) Oatmeal Olive oil (moderate amounts for salads and flavoring) Onions Oranges Pears Peas Peppers, green or red + +Fats, Oils, & Sweets + +KEY + +Sugars (added) + +Fat (naturally occurring and added) + +USE SPARINGLY + +These symbols show fat and added sugars in foods. + +Milk, Yogurt, & Cheese Group 2-3 SERVINGS + +Meat, Poultry, Fish, Dry Beans, Eggs, & Nuts Group 2-3 SERVINGS + +Vegetable Group 3-5 SERVINGS + +Fruit Group 2-4 SERVINGS + +Bread, Cereal, ✓ Rice, & Pasta Group 6-11 SERVINGS + +Source: U.S. Department of Agriculture/U.S. Department of Health and Human Services + +![](figure) + +Pickles Pineapple Popcorn, unsalted and unbuttered Pork (lean) 4 oz. per day Potatoes (Irish or sweet, with skin) one big or two small Radishes Rice (brown or wild) Salad dressing (no-fat) Salsa Soft drinks (no sugar) Soy products (tofu, etc.) Spinach Squash Sugar substitutes (Aspartame and Saccharine) Tomatoes Turkey breast (no skin, broiled or baked) 4 oz. per day Turnips greens Turnips Yams Yogurt (plain, unsweetened) Zucchini + +![](figure) diff --git a/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_29_pg1_pg1_repeat1.md b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_29_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6af2e7e4c75da7e9a0b4ee1b2eb79e7e11db4a25 --- /dev/null +++ b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_29_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +![](figure) + +![](figure) + +Lilienthal as well—he was having fun. He was to describe his flights, especially the ones where he could eke out more distance, as an “indescribable pleasure.” It is not only likely, but probable, that some of these incredible photographs were seen by a particular duo of young men in Dayton, Ohio. + +## Early Safety Analysis + +Lilienthal was relentless in his study of air movement and wind, and he recognized quickly what is common knowledge among hang gliders today—a sudden gust of wind can ruin your whole day. So meticulous and thorough was he that, from the time he first designed his sailing apparatus in 1888, he didn’t take his first flight until 1891. Before he flew, he published his theories on how man could fly in a book which was widely popular—“Der Vogelflug als Grundlage der Fliegekunst,” Birdflight as the Basis of Aviation. This book, published in 1889, consisted of the results of his various experiments with models in both natural wind and a crude wind device. Up to that point, it was all aerodynamic theory, but he was determined to put that theory into practice. That first flight, like most of his flights, was in a large large, monowing apparatus. He next experimented with increasing the square footage of the “wings” until the whole thing became too heavy to pick up. He even tried flapping the wings, just like a bird, before he settled on the practicality of “immovable wings.” + +![](figure) + +Modern hang glider enthusiasts will also recognize and appreciate what these experiments revealed—he could control his direction of flight by shifting his center of gravity. The design of his mono-winged glider allowed his legs to be free and fully movable, and with practice, all his landings ended standing up. After a series of experiments to try and develop more lift to soar longer, Lilienthal opted to try bi-wing gliders. He first built small, scale models from heavy paper. Those “aircraft” surprised him with their stability, and he concluded that the full-size gliders would be stable as well and not as susceptible to the irregularities of wind currents. In all, he designed and built 15 different models of mono-wing gliders and three bi-wing gliders, diff --git a/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_30_pg1_pg1_repeat1.md b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_30_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ede12100bb3bc68bddc9e42f6a282205efe2b838 --- /dev/null +++ b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_30_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +some vastly different from their predecessors, some only subtly so. There probably would have been a great many more bi-wing gliders except for his death in 1896. Many of the designs seemed whimsical—wings shaped like those of a bat, a triangular tail like some birds, wings that folded back out of the way for storage but with an infrastructure that looked like individual feathers. But they worked, even the ones with the flappable wings. (He didn’t launch by flapping those wings; rather, he took his usual leap off Fliegeberg, began to glide, and supplemented that with the occa- + +“So perfectly was the machine fitted together that it was impossible to find a single loose cord or brace, and the cloth was everywhere under such tension that the whole machine rang like a drum when rapped with the knuckles. As it lay on the grass in the bright sunshine, with its 24 square yards of snow white cloth spread before you, you felt as if the flying age was really commencing. Here was a flying machine, not constructed by a crank, to be seen at a county fair at 10 cents a head or to furnish material for encyclopedia articles on aerial navigation, but by an engineer of ability...a machine not made to look at, but to fly with.” Robert W. Wood, Boston Transcript Reporter, describing his first sight of a Lilienthal glider on August 2, 1896 + +## Aeronautical Homework + +In a way, Lilienthal’s experiments and his scientific writings about them, were the “homework” the Wright Brothers didn’t have to do. They didn’t have to design their early gliders from scratch because they had Lilienthal’s experiments to turn to. Conducted over only five years, Lilienthal’s flights numbered in excess of 2,000, and he was meticulous about documenting what did and didn’t work and learning from his mistakes. It is believed that from his first glider flight in 1891, he flew every day for the next five years, many of his flights longer than 800 feet. From those experimental flights, Lilienthal imparted to the Wrights the concepts of wing camber, a stabilizing vertical rudder in addition to a horizontal stabilizer, and a dedicated airfield from which to practice and experiment. Because of Lilienthal’s pioneering work, the Wright Brothers could cut to the chase, prove their concept through glider work, then concentrate on combining their design with Charles Taylor’s engine. The Wrights also learned the lesson of photography from Lilienthal. Whereas they weren’t to become the media darlings that Lilienthal became (not by his design), they recognized the need for their ultimate triumph to be captured on film. That famous photograph, a freeze-frame of history in the making, was indisputable. + +## Powered Flight—Almost + +Lilienthal had experimented with attaching, as he called it, a “dynamo” to an ornithopter design as early as 1893. The carbonic acid, gas motor produced all of two horsepower and was supposed to power the flapping of only the wingtips. Lilienthal decided after assembling it that it wouldn’t fly and, indeed, never attempted to test fly it. In 1895 he tried again, this time with a more powerful motor which was supposed to move almost the entire wing. He did try to test fly this configuration without success, and some scientists then and now believe he didn’t succedd because he hadn’t yet divorced himself from his fascination with bird flight, hence the focus on flapping wings. His experiments with powered airplanes didn’t include and his theoretical writings about powered flight didn’t involve propellers. Yet, with our perfect 20/20 hindsight many now believe he would have eventually abandoned his reliance on bird flight and come to the inevitable conclusion about propeller-generated thrust. Rather, because he was the engineer he was, he was dedicated to the time-honored trial and error method. + +## Prussian Hero + +Nevertheless, his persistence even in the face of his failures at powered flight made Lilienthal a hero to his people and to aviation enthusiasts, such as they were, around the world, perhaps even to the Wrights themselves. “The Flying Man,” “The Winged Prussian,” was certainly an inspiration to them and indispensable in their ultimate accomplishment. (However, one German engineer still didn’t believe that flight was possible, even given Lilienthal’s extensive photographic documentation, and referred to Lilienthal as “The Flying Squirrel.”) Sunday, August 9, 1896, started off as usual at Fliegeberg. The winds were favorable and promised the 48year old Otto Lilienthal hours of unimpeded gliding. So favorable did the winds appear to be that he opted that day for a mono-wing glider with a new approach to steering—opening and closing slits of cloth on the wings instead of shifting his body weight. (Some birds will “flare” their wingtip feathers to dissipate lift and make those “on a dime” turns. Lilienthal was attempting to duplicate this with a type of wing warping.) The launch was uneventful, but at an altitude of 50 feet, without warning a gust of wind pitched the glider upward. It stalled, and the force up the sudden pitch-up was apparently strong enough to break a section of the wing. + +![](figure) diff --git a/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_31_pg1_pg1_repeat1.md b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_31_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b2346955a16bff84a7bcdfd733858d0b5dc24011 --- /dev/null +++ b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_31_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +Perhaps he had time to appreciate the irony that despite his vast study of air currents and his many words written about the dangers of sudden gusts, he had been undone by that very thing which still plagues glider airmen today. Lilienthal’s broken bird vertically dived to earth, and the impact broke his spine. He lingered for a day, maybe with the knowledge that his injury would deprive him of ever again experiencing the indescribable pleasures of flight, and died. Typically Teutonic, Lilienthal’s most famous quote about his raison d’ etre was simultaneously dismissive and passionate: “To invent an airplane is nothing. To build one is something. But to fly is everything.” + +3 + +Phyllis Anne Duncan is the Manager, Management Systems Branch, in FAA’s Flight Standards Service. Request permission to reprint this article from . + +# Did you know... + +...that the Smithsonian’s National Air and Space Museum has an original (albeit restored) Lilienthal No. 11 glider, his most successful and popular design which was sold to a few adventurous souls in the 1890’s? + +...that the only American known to have purchased a Lilienthal glider is William Randolph Hearst, who didn’t fly it himself but hired a New Jersey man to do so as a publicity stunt to boost subscriptions to Hearst publications? + +...that Lilienthal’s exploits inspired the creation of the first glider club in the U.S.? + +...that American aviation pioneer Samuel Langley met Lilienthal but was “unimpressed” by one of his gliders? + +...that Lilienthal is considered the first, modern mass-media celebrity? + +# Question for a Century of Flight: + +### \(Hadhelived,wouldLilienthalhavebeatentheWright Brotherstopoweredflight?\) + +The debate on this question differs depending upon which side of the Atlantic you inhabit. German scientists and historians certainly believe that Lilienthal was definitely headed toward a powered airplane and was possibly only a year or less away from achieving that when he died. American aviation historians believe he was “years away” from accomplishing what the Wright Brothers did by building on his work. Nationalism aside, it did take Lilienthal five years of extensive and painstaking experimentation to reach the bi-wing glider design, a design he considered feasible for mounting a motor. Even if he had taken another five to perfect a glider and engine combination, that would still have put his speculative powered flight at 1901, two years ahead of the Wrights. However, alternative history is the realm of science fiction writers, and what remains true is that the Wrights were inspired and assisted by Lilienthal’s work. After all, they used body shifting to steer their initial gliders, incorporated their take on his wing warping design on later models, and put Charles Taylor’s engine on essentially a bi-wing glider. On December 17, 1903, they became in America every bit the sensation he had been in the relatively new country of Germany. But, could he have beat them to powered flight? Quite possibly, but that detracts none from the Wrights’ accomplishment. Rather than competitors, I prefer to think of them as his heirs and that he might have felt the same about two men who shared with him the “indescribable pleasure” of flight. + +![](figure) diff --git a/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_37_pg1_pg1_repeat1.md b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_37_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a13767aea383ff58fb1a45611d37aa7eaf723c21 --- /dev/null +++ b/outputs/multi_column/03b953c18a4f7d2bbe390940dec839395cdd_page_37_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +![](figure) + +## FAA-ISSUED AIRMAN CERTIFICATE INELIGIBILITY BASED ON SECURITY GROUNDS + +In the January 24, 2003, Federal Register, the FAA published a final rule which puts in place processes for the Transportation Security Administration (TSA) to notify an individual that he or she has been determined to pose a national security threat and to advise the FAA of its determination. The FAA is adding a section to Title 14 of the Code of Federal Regulations (14 CFR) parts 61, 63, and 65 to expressly make individuals who pose a security threat as determined by the TSA ineligible to hold certificates, ratings, and authorizations issued under those parts. This ineligibility means that the FAA will not issue a certificate, rating, or authorization to any applicant who has received an Initial Notification of Threat Assessment from TSA. The FAA will hold in abeyance the application pending the outcome of the TSA’s final threat assessment review. If an individual is issued a Final Notification of Threat Assessment, the FAA will deny an application for any airman certificate, rating or authorization. With regard to certificates already issued, the FAA will suspend an individual’s airman certificates after receiving the Initial Notification of Threat Assessment from the TSA. Suspension is appropriate in this circumstance, because the TSA’s initial assessment that an individual poses a security threat is still subject to review by the TSA’s Deputy Administrator and may be reversed. If at this point a U.S. citizen is still determined a threat, TSA’s Under Secretary will make the final determination. If a Final Notification of Threat Assessment is issued, the FAA will revoke the certificates; if an Initial Notification is withdrawn, the FAA will withdraw its certificate suspension. The eligibility standards adopted in this rulemaking rely on the threat assessments made by TSA. This reliance is based on the broad statutory authority and responsibility that the Aviation and Transportation Security Act, Public Law 107-71, placed in the Under Secretary with regard to intelligence information and threat assessments. The individual may respond in writing to this initial notification and provide any information the individual believes the TSA should consider. + +![](figure) + +## CIVIL AVIATION REGISTRY WEB SITE ADDS AIRMEN SERVICES ACCOUNT + +U.S. certificated airmen can open an online services account on the popular U.S. Civil Aviation Registry web site operated by the Federal Aviation Administration in Oklahoma City, at . The site has many other aircraft and airmen information options and averages nearly 2,500 visitors daily. The new service allows airmen to update their mailing addresses, as required by Federal aviation regulations. FAA needs current data to provide safety-related information to airmen as it becomes available. Future services will include the ability to receive Aviation Safety Program flyers through electronic mail. The Registry mails more than six million such flyers each year. The new service would not only allow airmen to receive this information electronically, but would save the FAA a part of the significant expense associated with printing and mailing many of these safety bulletins, said Mark Lash, Registry manager. “Future services could also include ordering replacement certificates, replacement knowledge test results, and a copy of the airman’s complete certification file,” he said. The Civil Aviation Registry in Oklahoma City manages and operates the national records system and database for the issue of all FAA airman certificates and the legal content of all airman certification records. The Registry directs the planning, development, and implementation of the regulations and systems associated with the registration of U.S. civil aircraft. The Registry Web site provides full sets of both the aircraft and airman databases, various forms used to do business with the Registry, and other useful information. In addition, there are services that can be requested and paid for online. Databases may be downloaded which include all information for aircraft. For airmen, Privacy Act information is not included, and addresses are not shown for airmen who chose not to have their address released. Registry staff responds to hundreds of thousands of customers each year. They issue more that 60,000 aircraft registration certificates and 180,000 airman certificates, and answer more than 140,000 telephone calls. They reserve 17,000 special aircraft registration numbers (N numbers), provide 200,000 copies of records, and update more than 108,000 addresses. Registry systems also provide information to FAA aviation safety inspectors, National Transportation Safety Board investigators, and law enforcement agencies to support aviation safety activities. + +![](figure) + +## TSA ISSUES AIRSPACE CONTROL MEASURES IN NATIONAL CAPITAL REGION + +FAA in conjunction with the Transportation Security Administration (TSA) has enhanced airspace control measures in the National Capital Region to a level consistent with National Threat Level Orange. “Terrorists are known to favor targets in the transportation sector and to consider our civil aviation system an arsenal of improvised weapons,” said DOT Under Secretary James M. Loy, diff --git a/outputs/multi_column/03ccfe8bb1096e76dd5c186c3ae24d5fe8ec_pg1_pg1_repeat1.md b/outputs/multi_column/03ccfe8bb1096e76dd5c186c3ae24d5fe8ec_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..891d342a7ae76f4d9bf91bca3bf61b1e25b1415a --- /dev/null +++ b/outputs/multi_column/03ccfe8bb1096e76dd5c186c3ae24d5fe8ec_pg1_pg1_repeat1.md @@ -0,0 +1,78 @@ +![](figure) + +![](figure) + +## 21st Annual Fall Conference on INTEGRATIVE MEDICINE IN WOMEN’S HEALTH + +## Loews Ventana Canyon Resort Tucson, Arizona ~ September 9-12, 2020 + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Please see the following information on air and ground transportation. If you haven’t registered for this conference, please go online to www.symposiamedicus.org to register. + +If you have any questions, please do not hesitate to contact us at (925) 969-1789, Monday-Friday, 8:30am-5:00pm, (Pacific Time) or email travel-tours@symposiamedicus.org. + +| HOTEL INFORMATION | Option #2 – Uber or Lyft | +| --- | --- | +| LOEWS VENTANA CANYON RESORT | • www.uber.com | +| 7000 N. Resort Drive | | +| Tucson, Arizona 85750 | • www.lyft.com | + +Phone: (520) 299-2020 + +# AIR TRAVEL INFORMATION + +The closest airport to the Loews Ventana Canyon Resort is + +# Tucson International Airport (TUS); however, lower fares + +can sometimes be found by flying into Phoenix Sky Harbor + +# International Airport (PHX). Tucson is approximately a 40 + +minute drive to the hotel, while Phoenix is approximately a 2 hour drive. + +Symposia Medicus has arranged for discount fares with Alaska, Delta, and United Airlines for this conference. To view more information, including airline discount codes, please visit the Conference Registration, Lodging, and Travel Information section of our online brochure at https://bit.ly/38OuBcF + +# GROUND TRANSPORTATION OPTIONS Option #1 – Car Rental We recommend that you rent a car to see the many + +sites of Tucson and the surrounding area. Symposia Medicus has arranged conference discounts with AVIS and Budget Car Rentals. Reservations can be made online or by phone. Please refer to the conference code and the airport location when making your reservations. + +| Rental | | Phone | Conference | +| --- | --- | --- | --- | +| | Website | | | +| Company | | Number | Code | +| | | | AWD # | +| AVIS | www.avis.com | 800-331-1600 | | +| | | | B766625 | +| | | | BCD # | +| Budget | www.budget.com | 800-772-3773 | | +| | | | U076767 | + +For driving directions from the Tucson International Airport (TUS), please visit https://goo.gl/maps/JbvRG4rqCaUZuehq9 + +# Option #3 – Taxi + +VIP Taxi and Yellow Cab are under contract with the Tucson Airport Authority (TAA) to meet arriving flights. + +To reach the cab stand from the main terminal (A and B gates), exit Baggage Claim on the lower level and cross the first roadway to the second roadway where taxis should be to your left. From the C gates, cross the roadway and go east toward the main terminal where you will find the taxis on your left as you near the center of the parking area. If there are no taxis, please use the phone at the cab stand to have one dispatched immediately. + +Under the contracts with the TAA, taxi rates are set at \$5.50 to start and \$2.25 per mile with a \$12.00 minimum fare. There can also be a charge for traffic delays of up to \$22.00 per hour. There are no additional charges for up to three passengers or normal baggage. + +# ADDITIONAL TRANSPORTATION OPTIONS + +For additional transportation options, please contact the concierge at Loews Ventana Canyon Resort at + +520. 299-2020. + +# PARKING + +Self and valet parking are complimentary for conference guests. diff --git a/outputs/multi_column/03e922d514407b071d31bfa0121f23d9ecff_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/03e922d514407b071d31bfa0121f23d9ecff_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a0d155fbf2eb9a0f4d4efcf03759926dbead2245 --- /dev/null +++ b/outputs/multi_column/03e922d514407b071d31bfa0121f23d9ecff_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,104 @@ +Universal factors affecting the incidence of musculoskeletal disorders in children can be divided into three groups, heavy school bag, furniture design that is not suitable by its dimensions to the body and inadequate posture when sitting (4). Wearing heavy school bags can be a risk for acute, short-term and chronic, long-term health problems (9, 10). The effects of heavy school bags and way of carrying is harmful not only for the back and spine, but also for other parts of the musculoskeletal system (11, 12). Frequent musculoskeletal disorders in the majority of children are manifested only occasional limiting movements with pain and usually have little clinical implications. However, in a small number of children these symptoms may be persistent and recurrent, leading to chronic musculoskeletal pain and other consequences. The key preventive measure is to identify precisely those children who could have long-term consequences (13). In the scientific literature of Bosnia and Herzegovina there are no epidemiological studies that deal with issues of musculoskeletal pain in children and various ergonomic factors. The goal of our study was to investigate the epidemiological indicators of musculoskeletal disorders in children and to determine their association with different ergonomic stress. + +## 2. MATERIAL AND METHODS + +Cross-sectional study included 1,315 primary school students, aged 8-12 years (652 boys and 663 girls) selected randomly from 13 schools, from all 13 municipalities in Tuzla Canton (Most populated Canton in Bosnia and Herzegovina). The survey was conducted during the period September–December 2015. The method that was used is “cluster sample” in the choice of subjects: random selection of 2-5 students one class repeatedly over 1 lecture (average daily number of lectures 4-5), and 20 was selected from each class, while from each educational institution is selected a total of 100 students who attended from 3 to 7 grade. Excluding factor for respondents was the existence of congenital or acquired deformities and physical disorders (children who use wheelchairs, diagnosed with child musculoskeletal disease, determined disparity between the lower extremities, problems with the foot etc.). The study was approved by the Ministry of Education, Science, Culture and Sport of Tuzla Canton. Prior to inclusion into the survey, respondents were provided with appropriate information, which explain the purpose, objectives and significance of the research. The survey was conducted by specially designed questionnaire, while diagnostic anthropometric measurements were made by two examiners. The questionnaire consisted of three parts. The first part consisted of data on demographic and individual characteristics of participants (age, gender, class), the second part is related to the assessment of the way and style of life and the performance of school tasks compared with ergonomic strain and the third part was standardized Nordic questionnaire for the analysis of muscle bone symptoms specially adapted for children’s age (14). The survey was conducted on a voluntary basis with respect for ethical provisions of student’s anonymity. After the survey was carried out anthropometric measurements of the following parameters: body and body weight for each student, and the weight of full and empty school bag that students that day took in school. Body height and weight were measured using scales GIMA model 27310 Astra. The scale is calibrated before each measurement. The obtained values of body weight and body height were used to calculate body mass index (BMI) as a ratio of body weight (kg) by the square of height (m). In order to assess the nutritional status of patients BMI values are expressed as a percentile value for the appropriate age and gender (15). In children, the BMI changes with age. The risk of developing obesity has children which is a BMI above the 85th percentile, and obese those with BMI greater than 95 percentiles for age. Statistical analysis: To analyze the results was used the standard Statistical Package for Social Sciences (SPSS) version 19.0. Statistical analysis used standard methods of descriptive statistics. To test the statistical significance of differences of selected variables were used \(\chi2-\)test and t-test. For multivariate analyzes was used non-parametric Spearman’s correlation test. Statistical analysis was performed with a confidence interval of 95%, a value of p <0.05 was considered as significant. + +## 3. RESULTS + +The mean age of respondents was 11.31±1.483 years, the average weight of a full school bag was 3.977±0.973 kg, average time sitting at school is 5.03±0.731 hours, and the average time sitting in front of computers 1,422±1,343 hours. Characteristics of patients are shown in Table 1. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
±Standard
Characteristics of subjectsMeanDeviation (SD)
Age (years)11.3111.483
School class5.0501.419
Weight (kg)41.56811.712
Height (cm)146.17510.605
Body mass index- BMI (m2)19.1693.679
Body mass index- BMI (percentile)60.89730.832
Empty weight of school bag0.5010.068
School bag full weight3.9770.973
Hours sitting in school5.0330.731
Hours sitting in front of computer1.4221.343
Home work sitting time1.9901.304
Musculosceletal pain1.4740.499
The frequency of pain when carrying bag2.6611.291
Time carrying bag to school2.7211.319
Time carrying bag from school2.7571.339
Position change carrying bag1.2930.455
+ +Table 1. Characteristics of all respondents (n= 1315) + +The frequency of musculoskeletal pain regardless of localization was 48%. The analysis of the localization of pain on the body, we recognize that dominate acute in 15% and chronic pain in both shoulders in 22%. Acute pain in the right shoulder has a frequency of 19% and left only 1% (children are right-handed). Acute and chronic pain in the neck has the same prevalence, but which is high for this age, or 17%. Alarmingly high frequency also had presence of chronic back pain–16%, and chronic pain in the chest–12% (Table 2). Estimated is also the association of acute musculoskeletal pain in patients and various ergonomic load (Table 3). There diff --git a/outputs/multi_column/04af23cb9eaaaf1b0462bafa176d0c0c315b_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/04af23cb9eaaaf1b0462bafa176d0c0c315b_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2003609dc10da02264f8337d6316cc231d3b5a4f --- /dev/null +++ b/outputs/multi_column/04af23cb9eaaaf1b0462bafa176d0c0c315b_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +action for explaining the ergogenic effects of caffeine. Doherty postulates that there are other central and peripheral elements involved. A probable reason for these ambiguities may be related to the training level of the subjects. + +The difference in the type of applied tests for measuring power (cycling, running, swimming) and the degree of caffeine consumption(5-6mg/kg and 250 mg) probably have led causing of this contradictory of the results. Therefore, the more precise and exceeding researches are necessary in order to be aware of the effect of caffeine consumption on 400-m freestyle activities. + +Another major finding of this investigation was that administration of 1.5 grams of L-carnitine did not affect on Performance time and Blood lactate concentrations. + +From the previous data, we find that CAF can induce an increase of FFA in blood and spare glycogen in the liver and muscle (LeBlanc, Jobin et al., 1985), and CAR can increase fat utilization by the transport of long-chain fatty acids into the mitochondrial matrix for β-oxidation (Broquist & Borum, 1982). + +The main function of Carnitine is to stimulate fatty acid production in mitochondria and reduce lactate production (Siliprandi et al., 1990). + +In a review study (Matera et al., 2003) also demonstrated that reduced lactate production during exercise is another function of L-Carnitine supplementation. In an investigations (Lee, Paik et al., 2003) also reported that 4g per day of Carnitine causes significantly lowers the blood lactate concentration. Increased fatty acid oxidation decreases fatigue upon Carnitine activation, and especially, lactate accumulation caused peripheral fatigue is decreased (Siliprandi et al., 1990). There is higher acetyl-carnitine concentration than acylcarnitine in skeletal muscle during high intensity exercise (Constantin-Teodosiu, Carlin, Cederblad et al., 1991; Minkler, Brass, et al., 1995). This high level of acetyl-CoA accumulation suppresses pyruvate dehydrogenase activation and affects acetyl-carnitine and lactate accumulation. Eventually, Carnitine intake has a positive effect on lactate concentration. However, a study (Chun Y, 2008) reported that 2g per day of Carnitine might not have a positive effect on lactate accumulation in Judoists. This implies that there is a close relationship between the amount of Carnitine intake and lactate recovery based upon subjects' characteristics. + +In a study (Colombani, et al., 1996) has previously been reported acute administration of L-carnitine did not affect the metabolism or improve the physical performance of the endurance-trained athletes during the run and did not alter their recovery. + +In a study they (Brass , Hoppel & Hiatt ,1994) found That Carnitine administration had no effect on muscle total carnitine content or the workload-dependent accumulation of acylcarnitines in skeletal muscle. Carnitine had no effect on the respiratory exchange ratio, muscle lactate accumulation, plasma lactate concentration, muscle glycogen utilization, or plasma beta-hydroxybutyrate concentration during exercise. Thus the skeletal muscle carnitine pool is segregated from dramatic changes in the plasma carnitine pool, and short-term administration of carnitine has no significant effect on fuel metabolism during exercise in humans.In a research(Jacobs, Goldstein, et al., 2009) examine the effects of a single dose of GPLC on the performance of repeated high intensity stationary cycle sprints with limited recovery periods in resistance trained male subjects and find that short-term oral supplementation of GPLC can enhance peak power production in resistance trained males with significantly less LAC accumulation. + +In the present study, perhaps the acetyl CoA/CoA ratio in the muscle was not influenced, ultimately not disrupting the accumulation of lactate.Further controlled experiments at varying intensities need to be performed to determine the potential benefits of Lcarnitine supplementation upon performance. diff --git a/outputs/multi_column/04af23cb9eaaaf1b0462bafa176d0c0c315b_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/04af23cb9eaaaf1b0462bafa176d0c0c315b_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..97db3b283d43f366fa9d9f8b4059f68288244de3 --- /dev/null +++ b/outputs/multi_column/04af23cb9eaaaf1b0462bafa176d0c0c315b_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,51 @@ +To summarize, the conclusion of current research is showing that consuming 3mg/kg caffeine, 1.5 g Lcarnitine and their combination has no meaningful effect on performance . More researches are necessary in order to investigate the acute effects of different amount of caffeine and L-carnitine on 400-m freestyle performance time and the blood lactate level. + +### Acknowledgement + +This research was supported by a grant from Karaj Branch, Islamic Azad University. The authors would like to thank Dr mehdi hedayati for his technical assistance. We express our gratitude to the staff of Biochemistry Laboratory at Endocrine Research Center of Shahid Beheshti University for their skillful technical assistance. + +## References + +Anselme F, Collomp K, Mercier B, Ahmaidi S, Prefaut C. 1992. Caffeine increases maximal anaerobic power and blood lactate concentration. European Journal of Applied Physiology and Occupation 65(2), 188-191. http://dx.doi.org/10.1007/BF00705079 + +Bell DG, McLellan TM. 2002. Exercise endurance 1, 3, and 6 h after caffeine ingestion in caffeine users and nonusers. Journal of Applied Physiology 93(4), 1227-1234. http://dx.doi.org/10.1152/japplphysiol.00187.2002 + +### Bell DG, Jacobs I, Ellerington K. 2001. Effect of + +caffeine and ephedrine ingestion on anaerobic exercise performance. Medicine and Science Sports and Exercise 33(8), 1399-1403. http://dx.doi.org/10.1097/00005768-200108000-00024 + +Beltz JD, Costill DL, Thomas R, Fink WJ, + +Kirwan JP. 1988. Energy demands of interval training for competitive swimming. Journal of Swimming Research 4(3), 5—9. + +### Biaggioni I, Paul S, Puckett A, Arzebiaga C. + +1991. Caffeine and theophylline as adenosine receptor antagonists in humans. The Journal of Pharmacology and Experimental Therapeutics 258(2), 588–593. PMID: 1865359. + +### Brass EP, Hoppel CL, Hiatt WR. 1994. Effect of + +intravenous L-carnitine on carnitine homeostasis and fuel metabolism during exercise in humans. Clinical Pharmacology and Therapeutics 55(6), 681-92. PMID: 8004884. + +### Broquist HP, Borum PR. 1982. Carnitine + +biosynthesis, nutritional implication. Advances in nutritional research 4, 181-204. http://dx.doi.org/10.1007/978-1-4613-9934-6_7 + +Carr A, Dawson B, Schneiker K, Goodman C, + +Lay B. 2008. Effect of caffeine supplementation on repeated sprint running performance. The Journal of Sports Medicine and Physical Fitness 48(4), 472- + +478. PMID:18997650. + +Chun Y. 2008. The effect on aerobic, anaerobic capacity, blood lipids & immunoglobulin from taking L-carnitine in Judo athletes. Yongin University. + +Collomp K, Ahmaidi S, Audran M, Chanal JL, + +Prefaut C. 1991.Effects of caffeine ingestion on performance and anaerobic metabolism during the Wingate test. International Journal of Sports Medicine 12(5), 439-443. http://dx.doi.org/10.1055/s-2007-1024710 + +Collomp K, Ahmaidi S, Chatard JC, Audran M, + +Préfaut C. 1992. Benefits of caffeine ingestion on sprint performance in trained and untrained swimmers. European Journal of Applied Physiology and Occupational Physiology 64, 377–380. http://dx.doi.org/10.1007/BF00636227 + +Collomp K, CaillaudC, Audran M, Chanal JL, + +Prefaut C. 1990. Effect of acute or chronic administration of caffeine on performance and on catecholamines during maximal cycle ergometer diff --git a/outputs/multi_column/04e85af12e0a127ebe1a8875250b0f3ab052_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/04e85af12e0a127ebe1a8875250b0f3ab052_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5b7cc3b400f8de805ab5c3351c1b866458cbacfd --- /dev/null +++ b/outputs/multi_column/04e85af12e0a127ebe1a8875250b0f3ab052_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,107 @@ +# RACE AND RESISTANCE STUDIES (RRS) + +### RRS 100 Introduction to Ethnic Studies (Units: 3) + +History, objectives, and philosophy of Ethnic Studies as a political project and academic field. The relational examination of communities of color/ indigenous nations and their experiences with structures of power and traditions of resistance. [CSL may be available] (This course is offered as ETHS 100 and RRS 100. Students may not repeat the course under an alternate prefix.) + +## Course Attributes: + +- D1: Social Sciences + +- Am. Ethnic & Racial Minorities + +- Global Perspectives + +- Social Justice + +### RRS 101 Introduction to Arab and Muslim Communities (Units: 3) + +Introduction to Arab and Muslim communities studies in U.S. and Americas and Asian and African ancestral homelands. Employing Arab, Muslim, Ethnic, Race and Resistance, Gender and Sexuality, American Middle East, Diasporas, Ethnicity Studies and Social Movement theory. + +## Course Attributes: + +- C2: Humanities + +- Am. Ethnic & Racial Minorities + +- Global Perspectives + +- Social Justice + +### RRS 103 Introduction to Pacific Islander Studies (Units: 3) + +Examination of historic and contemporary issues of and experiences related to Pacific Islander communities in the United States and across the Pacific Islander diaspora. (This course is offered as RRS 103 and AIS 103. Students may not repeat the course under an alternate prefix.) + +## Course Attributes: + +- U.S. History + +- D2: Social Sciences: US Hist. + +- Am. Ethnic & Racial Minorities + +- Global Perspectives + +- Social Justice + +### RRS 110 Critical Thinking and the Ethnic Studies Experience (Units: 3) + +Basic skills involved in understanding, criticizing, and constructing arguments by using materials reflective of experiences of Indigenous and racialized groups in the U.S. (This course is offered as ETHS 110 and RRS 110. Students may not repeat the course under an alternate prefix.) + +## Course Attributes: + +- A3: Critical Thinking + +- Am. Ethnic & Racial Minorities + +## RRS 201 SFSU's Palestinian Cultural Mural and the Art of Resistance (Units: 3) + +Critical investigation of the roles public art plays in transnational social justice movements, historically and currently. Examination of the history and legacy of Palestine Cultural Mural at San Francisco State University. + +## Course Attributes: + +- C2: Humanities + +- Am. Ethnic & Racial Minorities + +- Global Perspectives + +- Social Justice + +### RRS 212 Edward Said (Units: 3) + +Prerequisite: RRS 101. + +Critical investigation of Edward Said's scholarship and its influence in transnational social justice movements, historically and currently. Examination of the history, theory, and legacy of post-colonial studies, orientalism, Islamophobia, and Palestine. + +## Course Attributes: + +- C2: Humanities + +- Am. Ethnic & Racial Minorities + +- Global Perspectives + +- Social Justice + +### RRS 220 Race and Dis/Ability (Units: 3) + +Cultivate a better understanding about structural racism and disability activism. Explore key principles of disability justice, a framework developed by activists with disabilities in response to limitations in rights-based approaches and mainstream disability advocacy. study historical and contemporary discourses of law, medicine, and media that constructs certain bodies as "healthy" or "disabled." Analyze the political and ethical implications of sharing illness experiences as acts of resistance and care. + +## Course Attributes: + +- GE-F: Ethnic Studies + +## RRS 240 All Power to the People: Comparative Freedom Movements of the "Sixties" (Units: 3) + +Introduction to the history and comparative survey of the African American, Chicana/o, Native American, and Asian American protest and liberation movements of the "Long Sixties" (1945-1975). [CSL may be available] + +## Course Attributes: + +- U.S. History + +- D2: Social Sciences: US Hist. + +- Am. Ethnic & Racial Minorities + +- Social Justice diff --git a/outputs/multi_column/04e85af12e0a127ebe1a8875250b0f3ab052_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/04e85af12e0a127ebe1a8875250b0f3ab052_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9a67feedc159a12efa9048ed9ee9ec0fde695c0b --- /dev/null +++ b/outputs/multi_column/04e85af12e0a127ebe1a8875250b0f3ab052_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,105 @@ +# RRS 250 Race, Ethnicity and Power in America (Units: 3) + +Critical examination of political concepts, processes and constructions of power that center race and ethnicity within a comparative analysis of American ideals, institutions and laws. Includes a study of constitutional issues and state and local governmental processes. + +## Course Attributes: + +- U.S. Govt CA State Local Govt + +- D3: Social Sciences: US CA Gov + +- Am. Ethnic & Racial Minorities + +- Social Justice + +# RRS 252 Beyond Bars and Borders: Race and the Carceral State (Units: 3) + +Examine the intersection of race and the carceral state. A comparative exploration of how diverse communities of color have experienced and struggled against racialized regimes of incarceration and displacement. Highlights how these racialized regimes that center on controlling the movement (or lack thereof) of communities of color are shaped by class, gender, and nation. Studies race and the carceral state in both domestic and global/transnational terms. + +## Course Attributes: + +- U.S. History + +- D2: Social Sciences: US Hist. + +- Am. Ethnic & Racial Minorities + +## RRS 255 Voices in Exile: Arab and Muslim American and Civil Liberties post-9/11/2001 (Units: 3) + +Changes post 9/11/2001, focusing on how Arab and Muslim Americans are affected. The case of the LA8, Sami Al-Arian, and Rasmeah Odeh will be used as a case study to analyze how government actions have affected Arab and Muslim Americans' civil liberties. + +## Course Attributes: + +- D1: Social Sciences + +- Am. Ethnic & Racial Minorities + +- Global Perspectives + +- Social Justice + +# RRS 260 Introduction to Arab and Arab American Feminisms (Units: 3) + +Writings by Arab and Arab American feminists to explore assumptions on and about Arab and Arab American experiences in the United States from multiple geographical sites, spiritualities, occupations, sexualities, class backgrounds, and generations. + +## Course Attributes: + +- Global Perspectives + +- Social Justice + +# RRS 270 Creativity, Decolonization, and Social Justice in Oceania (Units: + +# 3) + +Historical survey of Pacific Islander literacies--not just on the page, but on the stage, on film, in community, in oratory, and in reading land, water, and environment. Introduction to the use of creative expression as a backbone of social justice and decolonization in Oceania. Focus on creative writing, literary studies, social justice, and diaspora in Oceania studies. Exploration of the ways Pacific Islanders have organized and resisted colonialism through artistic practice and the power of the word. + +## RRS 275 Introduction to Pacific Islander Literature: How To Read An Ocean (Units: 3) + +Examine Pacific Islander writers and their histories of shaping terms and definitions of literature within Oceania as a region and beyond. Explore Pacific Islander narratives about the intersections of gender, sexuality, race, colonialism, resistance, sovereignty, climate change, and understandings of connection to the environment through a wide range of reading materials, including novels, short stories, poetry, creative nonfiction, and academic essays. Emphasis on the ways in which Pacific Islander literatures shape complex and interconnected reflections of Oceania, ultimately speaking to the power of storytelling. + +## Course Attributes: + +- C2: Humanities + +# RRS 276 Race, Activism and Climate Justice (Units: 3) + +Examination of the intersection of race, socio-economics, political ecology and climate change on a global scale; overview of the scientific evidence for anthropogenic causes and impacts; and exploration of environmental justice, political ecology, disparate impacts on different peoples and activism on global and local levels. + +## Course Attributes: + +- B2: Life Science + +- Am. Ethnic & Racial Minorities + +- Environmental Sustainability + +- Global Perspectives + +- Social Justice + +## RRS 280 Disrupting Science Fiction: Race, Gender, and Alternative Futures (Units: 3) + +Interrogate dominant narratives of power in the genre of science fiction. Examine the intersections of race, gender class, and sexuality, centering how Indigenous people and people of color writers challenge oppression and create possibilities for the future. Includes examing the histories of slavery, removal, displacement, and colonization as well as resistance and liberation. + +## Course Attributes: + +- C2: Humanities + +- C3 or C2: Humanities/Lit. + +- Am. Ethnic & Racial Minorities + +# RRS 282 Art and Cultural Practices of Oceania (Units: 3) + +Acquire an understanding of the relationships of art, culture, and power to Pacific peoples through the various forms of art found within Oceania. The practice of critical analytical skills in art criticism. + +## RRS 285 Race, Sports, and Society (Units: 3) + +Examines connections between race, "politics" and high-profile professional sports in the United States and abroad. Multiple issues explored using interdisciplinary approach, including critical race theory and socio-historical and socioeconomic constructs. + +## Course Attributes: + +- GE-F: Ethnic Studies + +- Am. Ethnic & Racial Minorities diff --git a/outputs/multi_column/04e88521bffcae275b79ed2c89e24c1f8855_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/04e88521bffcae275b79ed2c89e24c1f8855_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b3c8ac8f807cad1376047d1b65edd72743d753cb --- /dev/null +++ b/outputs/multi_column/04e88521bffcae275b79ed2c89e24c1f8855_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Ravi Ramalingam 1 , K. K. Ramalingam 2 , A. V. Ramesh 3 , S. Mahesh Prabhu 4 , Manu Vergis 5 , N. Ahilasamy 6 + +ABSTRACT : The incidence of Papillary Thyroid Carcinoma in a Thyroglossal Cyst is rare. Only about 160 cases have been reported in the last 85 years. We report a case of Thyroglossal Cyst who underwent Sistrunk's Operation. The Cyst was reported to contain a focus of papillary thyroid carcinoma. In the absence of metastases in thyroid gland and neck nodes, only thyroid suppression with Thyroxine was given. After 1 year of follow-up there are no metastases. The importance of Sistrunk's operation lies not only in complete removal of Thyroglossal Cyst but also in management of small foci of Papillary thyroid Carcinoma. + +Key Words: Thyroglossal cyst, Papillary carcinoma + +INTRODUCTION + +Thyroglossal cyst is a common congenital neck mass resulting from persistence and dilatation of an epithelial tract formed during migration of thyroid during embryogenesis. Thyroid tissue is present in the cyst wall in more than 60% of cases (Maran,1997). We report a rare case of Thyroglossal cyst in which the thyroid tissue in cyst wall showed Papillary carcinoma. + +CASE REPORT + +A 22 year old female presented to our centre with complaints of a painless swelling in the neck which has been growing slowly in size over last 3 months. On examination there was a 2cms oval, cystic swelling in the subhyoid region to the left of midline. The swelling moved with deglutition and with protrusion of the tongue. X-RAY neck lateral view was normal. Thyroid Function Tests i.e. T3, T4, TSH and Ultrasonogram of Thyroid gland were normal. I-131 scan did not reveal any cold nodules in the thyroid gland. (Fig. I) There was no uptake of radioactive iodine by the swelling. A diagnosis of thyroglossal cyst was made and the patient underwent excision of the cystic swelling by Sistrunk's operation. The cyst, the body of hyoid and a cuff of central base of tongue were removed. + +The histological examination of the swelling revealed a focus of Papillary Carcinoma of Thyroid (Fig. II). The cyst wall had cuboidal lining which was resting on some + +granulation tissue and a fibromuscular wall with adipose tissue. One of the fragments showed a papillary lesion composed of true papillae lined by cells with overlapping nuclei, nuclear clearing, intranuclear cytoplasmic inclusions and nuclear grooves. The wall adjacent to this papillary lesion shows dilated cyst with colloid and pigmented macrophages. The patient was put on suppressive treatment of Tab Thyroxine 0.2mg OD. After 1 year patient is asymptomatic. Thyroid function tests and thyroid scan were normal. There was no evidence of secondaries in the neck. + +Fig. I: Preoperative thyroid scan showing thyroid in the normal position with no cold nodules. There is no uptake by the thyroglossal cyst. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/04e88521bffcae275b79ed2c89e24c1f8855_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/04e88521bffcae275b79ed2c89e24c1f8855_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..684cd4167bd249bfba433767bb87ebcc254ddfa8 --- /dev/null +++ b/outputs/multi_column/04e88521bffcae275b79ed2c89e24c1f8855_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Fig. II : Photomicrograph showing papillary fronds lined by cells with crowded, overlapping nuclei showing prominent nuclear clearing (orphan-Annie Nuclei) [H & E x 200 ] + +DISCUSSION + +Thyroglossal duct cyst is a common congenital neck mass. However less than 1% of the cysts show malignant changes (O'Connell et.al.,1998). In the past 85 years, about 160 cases have been reported of which less than 10 are in children (Yoo et.al.,1998)- an indication that perhaps the malignancy arises denovo in the thyroid tissue of the thyroglossal remnants. Papillary Carcinoma is the most common. Isolated cases of follicular carcinoma, hurthle cell carcinoma, squamous cell carcinoma and insular carcinoma are also reported. Foci of papillary carcinoma in thyroid gland were seen in 4 out of a series of 10 cases of thyroglossal cyst carcinoma with only 1 tumour larger than 1 cm. Incidence of cervical metastases have also been reported (Micolli et.al., 1998). + +Most commonly the diagnosis of papillary carcinoma in thyroglossal cyst is made postoperatively. With improved techniques of FNAC, it has been possible to diagnose about 20 cases preoperatively (Yang et.al.,2000). Thorough clinical evaluation to rule out metastases in the thyroid gland and neck by way of Ultrasonography of neck and thyroid gland is a must before surgery. Scintiscanning would reveal the presence of normal thyroid gland and any cold nodules therein. + +Biological behavior of papillary carcinomat of thyroglossal cyst and thyroid gland are similar. Microscopic focus of papillary carcinoma in a thyroglossal cyst without cystwall invasion can be managed by Sistrunk's operation alone. Postoperative thyroid suppression with thyroxine is advocated by some. More extensive involvement of the cyst and thyroid gland would require a total thyroidectomy (Kennedy et.al.,1998). Cervical metastases would necessitate a radical neck dissection. Recurrences are rare after adequate surgery and can be managed with radioiodine and radiotherapy. The prognosis is excellent in patients with papillary carcinoma in thyroglossal cyst as compared to other rarer types. + +REFERENCES + +1. AGD Maran (1997) : Benign diseases of neck. In: Alan G Kerr, John Hibberts, eds. Scott Brown's Otolaryngology. 6 th edn. Oxford : Butterworth -Heinemann, 5 / 16 / 2 2. O'Connell M, Grixti M, Harmer C. (1998) : Thyroglossal duct carcinoma : presentation and management. Clinical Oncology (Royal College of Radiologists) ;10 (3) : 186 -190. 3. Yoo KS, Chengazi VU, O'Mara RE. (1998) : Thyroglossal duct cyst with papillary carcinoma in an 11 year old girl. J Paediatric Surgery 33 (5) : 745 - 6 4. Micolli P, Pacini F, Basolo S, Iaconni P, Puccini M, Pinchera A. (1998) : Thyroid carcinoma in a thyroglossal duct cyst: Tumor resection alone or a total thyroidectomy? Ann de Chirurgie ; 52 (5) : 452 - 4 5. Yang YJ, Haghir S, Wanamaker JR, Powers CN. (2000) : Diagnosis of papillary carcinoma in a thyroglossal duct cyst by fine needle aspiration biopsy. Archives of Pathology and Laboratory Medicine ; 124 (1) : 139-42 6. Kennedy TL, Whitaker M, Wadih G. (1998) : Thyroglossal duct carcinoma : a rational approach to management. Laryngoscope ; 108 : 1154-8 + +Address for Correspondence : + +Dr. Ravi Ramalingam + +K. K. R. ENT Hospital & Research Institute, 827, Poonamallee High Road, Kilpauk, Chennai - 600 010. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/04f8254ed1a74096fc98c7e069af79fc9fcf_pg1_pg1_repeat1.md b/outputs/multi_column/04f8254ed1a74096fc98c7e069af79fc9fcf_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9022abfbf0952b6d7d255ef98ea352da76beb64f --- /dev/null +++ b/outputs/multi_column/04f8254ed1a74096fc98c7e069af79fc9fcf_pg1_pg1_repeat1.md @@ -0,0 +1,75 @@ +# ENGINEERING (ENGR) + +### 100 Level Courses + +ENGR 107: Introduction to Engineering. 2 credits. Introduces engineering profession fundamentals and problem-solving. Topics include description of engineering disciplines, functions of the engineer, professionalism, ethics and registration, problem solving and representation of technical information, estimation and approximations, and analysis and design. Offered by Electrical & Computer Engineer. Limited to two attempts. + +Mason Core: Information Technology: Ethics Only + +#### Registration Restrictions: + +Students with the terminated from VSE major attribute may not enroll. + +#### Schedule Type: Lecture + +### 200 Level Courses + +ENGR 202: Thermodynamics. 3 credits. Offered by Electrical & Computer Engineer. May not be repeated for credit. + +#### Schedule Type: Lecture + +### 300 Level Courses + +ENGR 395: Engineering Internship. 0-3 credits. Students will participate in experiential learning in an industrial setting. Students must identify work opportunity and seek advisor approval prior to registering. Course credit will not satisfy degree requirements. Offered by Electrical & Computer Engineer. May be repeated within the degree for a maximum 6 credits. + +Recommended Prerequisite: Completion of at least 30 credit hours. + +#### Schedule Type: Internship + +## ENGR 396: Engineering Co-Op I. 0-3 credits. + +1st Semester of a multi-semester co-operative education experience. Students will apply concepts and theories from the classroom to an industrial setting. Students must identify work opportunity and seek advisor approval prior to registering. Course credit will not satisfy degree requirements. Offered by Electrical & Computer Engineer. May not be repeated for credit. + +Recommended Prerequisite: Completion of at least 30 credit hours. + +#### Schedule Type: Lecture + +ENGR 397: Engineering Co-Op II. 0-3 credits. Second Semester of a multi-semester co-operative education experience. Students will apply concepts and theories from the classroom to an industrial setting. Students must continue employment from ME 396 and seek advisor approval prior to registering. Course credit will not satisfy degree requirements. Offered by Electrical & Computer Engineer. May not be repeated for credit. + +#### Recommended Prerequisite: ME 396. + +#### Schedule Type: Internship + +### 400 Level Courses + +ENGR 498: Independent Study in Engineering. 1-3 credits. Directed self-study of special topics of current interest in ENGR. Notes: May be repeated if topics substantially different. Offered by Electrical & Computer Engineer. May be repeated within the term for a maximum 6 credits. + +#### Registration Restrictions: + +Students with the terminated from VSE major attribute may not enroll. + +Schedule Type: Independent Study + +ENGR 499: Special Topics in Engineering. 0-4 credits. Topics of special interest to undergraduates. Notes: May be repeated if topics substantially different. Offered by Electrical & Computer Engineer. May be repeated within the term for a maximum 11 credits. + +#### Registration Restrictions: + +Students with the terminated from VSE major attribute may not enroll. + +#### Schedule Type: Lecture + +### 700 Level Courses + +ENGR 794: Graduate Internship. 0-3 credits. Students with an Internship/Externship/Co-Op opportunity will gain practical experience while engaging in an experiential learning opportunity. Offered by Volgenau School of Engineering. May be repeated within the degree for a maximum 6 credits. + +Recommended Prerequisite: Completion of at least 18 credit hours. + +#### Registration Restrictions: + +Enrollment is limited to Graduate or Non-Degree level students. + +Students in a Non-Degree Undergraduate degree may not enroll. + +Enrollment limited to students in the Volgenau School of Engineering college. + +#### Schedule Type: Internship diff --git a/outputs/multi_column/0514f6672af23035c53e13fa9f5d7e17e4a4_page_18_pg1_pg1_repeat1.md b/outputs/multi_column/0514f6672af23035c53e13fa9f5d7e17e4a4_page_18_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d6bdc19c9f9514e9e76c1aafd9b8487e5e977fa8 --- /dev/null +++ b/outputs/multi_column/0514f6672af23035c53e13fa9f5d7e17e4a4_page_18_pg1_pg1_repeat1.md @@ -0,0 +1,63 @@ +Heinesch, B., Yernaux, M., Aubinet, M., 2007. Some methodological questions concerning advection measurements: a case study. Boundary-Layer Meteorol. 122, 457e478. + +Helfter, C., Famulari, D., Phillips, G.J., Barlow, J.F., Wood, C., Grimmond, C.S.B., Nemitz, E., 2011. Controls of carbon dioxide concentrations and fluxes above central London. Atmos. Chem. Phys. 11 (5), 1913e1928. + +Hutyra, L.R., Munger, J.W., Hammond Pyle, E., Saleska, S.R., Restrepo-Coupe, Daube, B.C., de Camargo, P.B., Wofsy, S.C., 2008. Resolving systematic errors in estimates of net ecosystem exchange of CO2 and ecosystem respiration in a tropical forest biome. Agric. For. Meteorol. 148, 1266e1279. + +Iamarino, M., Beevers, S., Grimmond, C.S.B., 2012. High-resolution (space, time) anthropogenic heat emissions: London 1970e2025. Int. J. Climatol. 32 (11), 1754e1767. + +Iwata, H., Yadvinder, M., van Randow, C., 2005. Gap-filling measurements of carbon dioxide storage in tropical rainforest canopy airspace. Agric. For. Meteorol. 132, 305e314. + +Jarvis, P.G., Massheder, J.M., Hale, S.E., Moncrieff, J.B., Rayment, M., Scott, S.L., 1997. Seasonal variation of carbon dioxide, water vapour, and energy exchanges of a boreal black spruce forest. J. Geophys. Res. Atmos. 102 (D24), 28953e28966. + +Kotthaus, S., Grimmond, C.S.B., 2012. Identification of micro-scale anthropogenic CO2, heat and moisture sources e processing eddy covariance fluxes for a dense urban environment. Atmos. Environ. 57, 301e316. + +Kotthaus, S., Grimmond, C.S.B., 2014a. Energy exchange in a dense urban environment e Part I: Temporal variability of long-term observations in central London. Urban Clim. 10 (2), 261e280. + +Kotthaus, S., Grimmond, C.S.B., 2014b. Energy exchange in a dense urban environment e Part II: Impact of spatial heterogeneity of the surface. Urban Clim. 10 (2), 281e307. + +Kowalksi, A.S., 2008. Comment on “the storage term in eddy flux calculations”. Agric. For. Meteorol. 148, 691e692. + +Lietzke, B., Vogt, R., 2013. Variability of CO2 concentrations and fluxes in and above an urban street canyon. Atmos. Environ. 74, 60e72. + +Lindberg, F., Grimmond, C.S.B., 2011. Nature of vegetation and building morphology characteristics across a city: Influence on shadow patterns and mean radiant temperatures in London. Urban Ecosyst. 14, 617e634. + +Microsoft, Simmons, 2011. Strand Campus, King's College London, UK, 51.511946, -0.116481. (Online). MTcxNzAwJmx2bD02JnN0eT1yJmVvPTAmcT1XQzJSJTIwMkxT 14.09.15). + +https://www.bing.com/maps/#Y3A9NTIuMjE3NDk5fjAu (accessed + +€ + +Molder, M., Lindroth, A., Halldin, S., 2000. Water vapour, CO2, and temperature profiles in and above a forestdaccuracy assessment of an unattended measurement system. J. Atmos. Ocean. Technol. 17, 417e425. + +Nemitz, E., Hargreaves, K.J., McDonald, A.G., Dorsey, J.R., Fowler, D., 2002. Micrometeorological measurements of the urban heat budget and CO2 emissions on a city scale. Environ. Sci. Technol. 36, 3139e3146. + +Oke, T.R., 1987. Boundary Layer Climates. Routledge, London. + +Press, W.H., Rybicki, G.B., 1988. Fast algorithm for spectral analysis of unevenly sampled data. Astrophys. J. 338, 277e280. + +R Development Core Team, 2012. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing. Austria, Vienna. + +Roth, M., 2000. Review of atmospheric turbulence over cities. Q. J. R. Meteorol. Soc. 126, 941e990. + +Salmond, J.A., Oke, T.R., Grimmond, C.S.B., Roberts, S., Offerle, B., 2005. Venting of heat and carbon dioxide from urban canyons at night. J. Appl. Meteorol. 44, 1180e1194. + +Satterthwaite, D., 2008. Cities' contribution to global warming: notes on the allocation of greenhouse gas emissions. Environ. Urban. 20 (2), 539e549. + +Siebicke, L., Steinfeld, G., Foken, T., 2010. CO2-gradient measurements using a parallel multi-analyzer setup. Atmos. Meas. Tech. 4 (3), 4383e4421. + +Simpson, I.J., Thurtell, G.W., Neumann, H.H., Den Hartog, G., Edwards, G.C., 1998. The validity of similarity theory in the roughness sublayer above forests. Boundary-Layer Meteorol. 87, 69e99. + +Torrance, C., Compo, G.P., 1998. A practical guide to wavelet analysis. Bull. Am. Meteorol. Soc. 79 (1), 61e78. + +Velasco, E., Roth, M., 2010. Cities as net sources of CO2: Review of atmospheric CO2 exchange in urban environments measured by eddy covariance technique. Geogr. Compass 4/9, 1238e1259. + +Vogt, R., Christen, A., Rotach, M.W., Roth, M., Satyanarayana, A.N.V., 2006. Temporal dynamics of CO2 fluxes and profiles over a Central European city. Theor. Appl. Climatol. 84, 117e126. + +Ward, H.C., Kotthaus, S., Grimmond, C.S.B., Bjorkegren, A., Wilkinson, M., Morrison, W.T.J., Evans, J.G., Morison, J.I.L., Iamarino, M., 2015. Effects of urban density on carbon dioxide exchanges: Observations of dense urban, suburban and woodland areas of southern England. Environ. Pollut. 198, 186e200. + +Wofsy, S.C., Goulden, M.L., Munger, J.W., Fan, S.-M., Bakwin, P.S., Daube, B.C., Bassow, S.L., Bazzazz, F.A., 1993. Net exchange of CO2 in a mid-latitude forest. Science 260 (5112), 1314e1317. + +Xu, L.-K., Matista, A., Hsiao, T.C., 1999. A technique for measuring CO2 and water vapour profiles within and above plant canopies over short periods. Agric. For. Meteorol. 94, 1e12. + +Yang, B., Hanson, P.J., Riggs, J.S., Pallardy, S.G., Heuer, M., Hosman, K.P., Meyers, T.P., Wullschleger, S.D., Gu, L.-H., 2007. Biases of CO2 storage in eddy flux measurements in a forest pertinent to vertical configurations of a profile system and CO2 density averaging. J. Geophys. Res. 112, D20. diff --git a/outputs/multi_column/0514f6672af23035c53e13fa9f5d7e17e4a4_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0514f6672af23035c53e13fa9f5d7e17e4a4_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5c47d0aea292edc9b339463618ffce3e2cbee966 --- /dev/null +++ b/outputs/multi_column/0514f6672af23035c53e13fa9f5d7e17e4a4_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +transport out of the volume) and fully turbulent conditions with negligible storage. In urban environments during stable atmospheric conditions the DCS term will be non-negligible (Helfter et al., 2011); for example, DCS was found to be five times the magnitude of the turbulent vertical flux term (FCO2) close to dawn and dusk in suburban Vancouver, Canada (Crawford and Christen, 2014). Other urban studies found DCS to be smaller, but still significant, with maximum DCS values 11% and 22% of the magnitude of FCO2 in Edinburgh, Scotland (Nemitz et al. 2002) and Basel, Switzerland (Feigenwinter et al. 2012), respectively. Similarly, in rural environments horizontal advection may be non-negligible (e.g., Aubinet et al., 2003). This paper focuses on the methodological considerations when assessing DCS from a vertical profile in an urban environment. Future manuscripts will address horizontal variation and advection. Of three studies discussed above (Vancouver, Edinburgh, Basel) with reported urban CO2 storage values, only one (Vancouver, Crawford and Christen, 2014) presented values derived from a data-set of longer than one month; however, both these values and those reported for Edinburgh by Nemitz et al. (2002) were calculated based on the assumption of a constant relation between carbon dioxide concentration ([CO2]) measured above the blending height and the concentration in the street canyon. In contrast, for Basel, Feigenwinter et al. (2012) did not make this assumption and reported DCS calculated from [CO2] at ten levels; however, the results are only for one month (15th June to 15th July 2002). There is therefore scope to improve not only the understanding of the processes affecting CO2 storage over a greater range of meteorological and anthropogenic conditions, but also to develop recommendations for future measurement programmes. The objective of this paper is to evaluate potential approaches for such studies, illustrated with examples from, and analysis of, high temporal resolution data collected at 10 locations from 6.5 to 46.4 m above ground level between 2011 and 2014 at King's College London, in Central London, UK. The paper is organized as follows. In the rest of this Section 1 we provide a brief background of how CO2 storage is calculated and then (Section 2) a discussion of the methods used in this paper. This is followed by an exploration of the temporal variation of CO2 storage (Section 3) and the relation between measured CO2 storage and anthropogenic and natural factors in a highly urbanised environment (Section 4). The required number and placement of sample points for CO2 storage measurements in a deep urban street canyon is addressed (Section 5) and the effect of sensor response and sampling interval on calculated CO2 storage is tested (Section 6). At the processing stage, three different temporal and spatial interpolation methods are evaluated against measured data (Section 7). Finally, the impact of CO2 storage calculated by two different methods on the turbulent vertical CO2 flux is assessed. The Supplementary material (noted by S.1 to S.9), includes the notation with corresponding units (S.1) used in the text, further information on CO2 storage calculation (S.2), previous CO2 storage studies (S.3), equipment (S.4), meteorological characteristics (S.5), example time series (S.6), variations of CO2 with friction velocity, wind direction and height above ground level (S.7, S.8) and further references (S.9). The online version of this paper provides the figures in colour. + +### 1.1. Calculation of CO2 storage + +There are two main approaches to calculating CO2 storage flux density, i.e., the rate of change of CO2 per unit area below the Eddy Covariance (EC) measurement height. Here they are referred to as the ‘single height’ and the ‘profile’ approaches. For a brief discussion of the theory and some reported results, see Supplementary material S.2 and S.3, respectively. For a more in depth discussion of the theoretical considerations regarding CO2 storage the reader is referred to Finnigan (2006) and subsequent discussion (Kowalksi, 2008; Finnigan, 2009). The approach to calculate CO2 storage depends upon the number of vertical locations at which CO2 concentration ([CO2], the symbol [ ] is used to indicate concentration) data are collected. In the first approach, ‘single height’ CO2 storage (DCSS) is calculated from [CO2] data at one location, usually by eddy covariance equipment in the inertial sub-layer (Nemitz et al., 2002; Crawford and Christen, 2014). In the second approach, the ‘profile’ method, DCS is calculated from data collected at multiple heights (DCSP). The profile method uses a vertical [CO2] profile at heights zi, which is generally measured by cycling through all the sample locations within a set time period with a data-logger controlled valve array € + +(Xu et al., 1999; Molder et al., 2000; Vogt et al., 2006; Hutyra et al., 2008). This cycle period may not be the same as the averaging period used in the DCSP calculation. For example, measurements collected with a sampling interval, ts, of 2 Hz for 75 s at 8 heights, giving a full profile cycle every 10 min, may be used to calculate DCSP with an averaging period (T) of 30 min. The storage is calculated as the sum of the changes in time averaged concentration ([CO2]i) between time t = -T/2 and t = T/2 for each location (i) in the profile, weighted by the vertical span, Dzi, over which each profile measurement is considered to be representative and divided by the averaging period (T), which can be expressed as (modified from Aubinet et al., 2005): + +\[\text{DC}_{\text{SP}}= \frac{1}{\mathrm{T}} \mathrm{X}_{\mathrm{i}} \overline{[\text{CO}_{2}]}_{\mathrm{i};\mathrm{t}=} \tfrac{\mathrm{T}}{2} - \overline{[\text{CO}_{2}]}_{\mathrm{i};\mathrm{t}=-} \tfrac{\mathrm{T}}{2} _{\text{Dz}_{\mathrm{i}}}\] (1) + +If the measurements at each height are not made concurrently, [CO2] at each height may first be interpolated in time to generate instantaneous profiles from which DCSP can be calculated, though this is neglected in some cases (Iwata et al., 2005). The impact of interpolation on calculated DCSP is discussed further in Section 7. The single height method is a simplification of the profile method to one height, which is usually the height of the eddy covariance equipment. The change in [CO2] with time at zh (D[CO2]/Dt) is weighted by the vertical distance from the ground to the measurement point (zh). The single height CO2 storage (DCSS) is given by (modified from Nemitz et al., 2002): + +\[\text{DC}_{\text{SS}}= \frac{\mathrm{D}[\text{CO}_{2}]}{\text{Dt}} \mathrm{z}_{\mathrm{h}}\] (2) + +As the data are continuous, the change in the instantaneous CO2 concentration with time (D[CO2]/Dt) can be used instead of the change in the time averaged CO2 concentration with time ([CO2]/Dt), though it may still be advisable to average in time to reduce measurement noise (Finnigan, 2006). The DCSS calculation assumes any change in [CO2] below the measurement height results in a change of equivalent magnitude at the measurement height. This assumption appears not to be supported by any evidence in the literature; reported diurnal cycles of CO2 mixing ratios in the roughness sub-layer over both rural (e.g., Xu et al., 1999) and urban (e.g., Lietzke and Vogt, 2013) surfaces are known to vary with height. This problem is particularly acute during periods of low turbulence, such as at night or during cold weather, where measurements above the surface layer may become decoupled from processes near ground level (Helfter et al., 2011). If temporal variability is large compared to the spatial variability, the single height method may provide a more accurate measure of storage than the profile method as the maximum data availability at each sample location for the latter may be 1/k of the total time diff --git a/outputs/multi_column/055c2edec4677b71f7bb6a759ebacc701bb1_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/055c2edec4677b71f7bb6a759ebacc701bb1_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d72a834081fc469740b85506780b82af4da5d9d4 --- /dev/null +++ b/outputs/multi_column/055c2edec4677b71f7bb6a759ebacc701bb1_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +![](figure) + +Figure 5. Longitudinal distribution of CCCS values as a function of month and hour (UTC).[^inferred] + +![](figure) + +Figure 5. Longitudinal distribution of CCCS values as a function of month and hour (UTC).[^inferred] + +Figure 5. Intensity distribution of CG flashes as a function of month and time (UTC) averaged over 2001-2011. + +to lower CG activity and vice versa lower Z values are related to higher CG activity. In addition, we obtain with the grouping algorithm that on average a CC flash consists out of 7 CC signals, whereas for every CG stroke 5 CC signals are detected within a given CG flash. + +# C. Annual variation + +Fig. 2 shows an annual variability in amount of CG detections. This behavior is found as well when looking at the total lightning data (not shown here). 2010 clearly is the year with the least lightning activity, followed in 2011 with the largest amount of lightning detections. Annual variations are found as well in other parts of the globe. Hence, one could wonder what causes a sudden increase/decrease between subsequent years. The onset of thunderstorms has been studied by many authors in the past and various elements are found to impact the development of convective systems. One such factor is the convective available potential energy (CAPE); an indicator of atmospheric instability. Large values of CAPE imply that sufficient updraft velocities are available for the development of a thunderstorm. This in its turn leads to the necessary charge separation and subsequent occurrence of lightning discharges. An increase in lightning activity with CAPE has been demonstrated for instance by [8] and [9]. CAPE in its turn is controlled by the wet bulb temperature. A relation between lightning activity and surface wet bulb temperature was quantified for the first time in [10]. Some further investigation is needed to clarify whether during 2010 average CAPE values were rather low compared to 2011 to account for the observed discrepancies. + +# D. Seasonal and daily variation + +The CG lightning activity as a function of month and time (UTC) is plotted in Fig. 5, averaged over 2001-2011. It clearly shows a seasonal dependence with lightning dominating during the summer months. On average 95% of annual lightning registrations are recorded between May and September with a lightning peak in June. Furthermore, above 70% of the activity takes place in the afternoon with a maximum between 15:00-16:00 UTC. + +### V. TRANSMISSION LINES + +High-voltage transmission lines between 30kV and 380kV in Belgium are mainly operated by ELIA. These lines have lengths of up to a few tens of kilometers, making them vulnerable to direct lightning hits or flashover events. Outage reports were provided by ELIA for 2011. In addition to line number and voltage level, the time of electrical failure with a timing accuracy of about 1-2s and the cause of the disruption is provided for each outage. The latter one is either classified as coming from an unknown source or is meteorological related, i.e., caused by lightning. A total number of 204 outages were reported in 2011, of which 117 are lightning related. We apply this to the CG detections of OP and TP. An outage report is correlated to a CG detection if the time difference between the time stamp of the outage and the CG detection is within 5s, and the distance between the position of the CG and a tower belonging to the line is within 5km. From this, we find that out of the 117 lightning related outages OP and TP find in 56 and 86 of the cases, respectively, a CG detection that meets the above criteria. Both OP and TP find two additional correlations between a CG detection and an outage report with unknown cause. The lower amount of matches found by OP can be explained by the lower location accuracy (LA) of the system compared to TP. From the ground-truth campaign in August 2011 [7] the location accuracy has been derived for OP and TP using those CG flashes in the camera’s field of view whose strokes follow the same channel. As the lower part of the channel is unresolved, the derived LA values are upper limits. A LA of 6km and 1km is found for OP and TP, respectively, owing to the different methodology in locating LF sources. + +## VI. CONCLUSIONS + +We have presented total lightning characteristics over Belgium. The data is based on the Belgian lightning detection network over an 11-year period spanning 2001 through 2011. The amount of detections varies over the years and no clear trend is noticeable. The spatial lightning distribution over Belgium is somewhat inhomogeneous. However, this inhomogeneity could be at least partly attributed to the positions of the various sensors favoring detections in the center of Belgium. The latter needs further investigation. A mean CG stroke and flash density is found ranging from 0.74-1.8/km2/yr and 0.48-0.99/km2/yr, respectively. The CC/CG flash ratio experiences a yearly variation with an average value of 1.94. Most of the lightning activity takes place during the summer months with a peak in the afternoon. In addition, CG detections of 2011 have been correlated to outage reports of high-voltage transmission lines as well. A lower amount of CG detections observed by OP overlap with an outage report + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/056112089988fe1892ffa833c0a8b2790e47_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/056112089988fe1892ffa833c0a8b2790e47_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..12bed17f7d1cddf9d495fd603a940154d7f32697 --- /dev/null +++ b/outputs/multi_column/056112089988fe1892ffa833c0a8b2790e47_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +# Glossary of Grinding Terms + +Arc of Cut: The part of the wheel that contacts the workpiece. Aspect Ratio: The ratio of an abrasive’s grain length to its width. Cermet: A heat-resistant alloy formed by compacting and sintering together a metal and a ceramic material. Continuous Dressing: A process where a diamond dressing roll sharpens the grinding wheel by removing dull grits all the time the wheel is machining the workpiece. Creep-Feed Grinding: A process where a very soft and porous grinding wheel takes a deep cut in one slow pass. Well-suited for difficult-to-machine materials, the process offer a high stock-removal rate with accurate form retention. Cylindrical Grinding: A process for machining round components. Dressing: Removal of undesirable material from a “loaded” grinding wheel by using a diamond tool. Dry Machining: A metal-removal operation where coolant is not applied to the cutting tool/workpiece interface. Friability: The ability of an abrasive to fracture. Hard Turning: Turning hardened metal on a lathe to eliminate grinding it. ID Grinding: A process that removes metal from the inside diameter of holes or profiles by applying a very small, high-rpm grinding wheel. Reciprocal Grinding: A process where the workpiece is mounted on a table that moves back and forth beneath the grinding wheel. Swarf: The mass of chips and debris remaining after grinding. Truing: Application of a diamond tool to a grinding wheel to ensure roundness and concentricity. + +are impervious and have no porosity. Care must be taken to apply the grinding fluid properly to plated and metal bond grinding wheels to prevent them from hydroplaning. Significant hydrodynamic pressures in the arc of cut can lift the wheel from the work-piece surface, resulting in poor surface finish and high wheel wear. The choice of bond and abrasive go hand in hand. For example, CBN might be the abrasive of choice if the wheel form is to remain exactly the same over the life of the wheel and it will stay on the machine spindle until spent. Since CBN conducts heat so well, a metal bond is advantageous. This combination provides a cool-cutting wheel, since the heat flows into the grain and wheel and away with the coolant rather than into the workpiece. There are two types of metal bond: plated and sintered. Plated wheels are never dressed; they are made to the exact form and grind until spent. Sintered wheels are generally dressed by the electrical discharge machining process while off the grinder, and then are mounted like a plated wheel. Both sintered and plated wheels need to be set up to minimize spindle runout: 0.0005" or less. Minimal spindle runout is especially important for metal bond wheels. Because the grains protrude a short distance above the bond, runout of 0.001" might cause excessive wear to one portion of the wheel while another section’s grains remain sharp. Some plated applications can form very tight radii (0.005" or so), but this + +![](figure) + +![](figure) + +Pictured are various metal-bonded diamond wheels for ceramic OD and ID cylindrical grinding. + +bond is generally reserved for more open forms with radii greater than 0.020". Often, plated wheels are applied in high-speed grinding applications and sintered wheels are used on ceramics. Solid metal wheels have little forgiveness for vibration, runout and fluid flow. If the grinding machine, part and/or fixture lack rigidity and/or the machine is old with less-than-perfect bearings and without an on-machine balancer, then the unforgiving plated wheel may cause wheel-life, surface-finish and surface-integrity problems. A resin bond would be a better choice, based on the condition of the machine tool and vibrational instability. Resin bonds have excellent vibration-damp-ing capabilities. However, the wheel would need to be trued and dressed, and there are costs associated with dressing devices and dressing time. Vitrified bonds are the most popular bond, as they make for a porous wheel. Vitrified bonds allow effective application of the grinding fluid to the arc of cut and provide ample chip clearance for the grinding swarf. Vitrified bonds are easily dressed to shape and sharpness with diamond dressing tools. This concludes the first part of “Abrasive Lessons.” The second installment will appear in the April edition. + +### About the Author + +Stuart Salmon is president of Advanced Manufacturing Science and Technology, Rossford, Ohio. diff --git a/outputs/multi_column/05a0e5bc2881eb1d246b2e41906bf8b24de2_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/05a0e5bc2881eb1d246b2e41906bf8b24de2_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..13fb5390524ed14fb1f1dbd4d8d4495a345da514 --- /dev/null +++ b/outputs/multi_column/05a0e5bc2881eb1d246b2e41906bf8b24de2_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,39 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Acta Crystallographica Section C + +Crystal Structure + +Communications + +ISSN 0108-2701 + +Proton-transfer and non-transfer in compounds of quinoline and quinaldic acid with L-tartaric acid + +Graham Smith, a* Urs D. Wermuth b and Jonathan M. White c + +a School of Physical and Chemical Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, Queensland 4001, Australia, b School of Science, Griffith University, Nathan, Queensland 4111, Australia, and c School of Chemistry, University of Melbourne, Parkville, Victoria 3052, Australia Correspondence e-mail: g.smith@qut.edu.au + +Received 12 October 2006 + +Accepted 27 October 2006 + +Online 30 November 2006 + +The structures of two compounds of L-tartaric acid with quinoline, viz. the proton-transfer compound quinolinium hydrogen (2R,3R)-tartrate monohydrate, \(C_9H_8N^+ \cdot C_4H_5O_6^-\) , \(H_2O\) , (I), and the anhydrous non-proton-transfer adduct with quinaldic acid, bis(quinolinium-2-carboxylate) (2R,3R)-tar-taric acid, \(2C_{10}H_7NO_2 \cdot C_4H_6O_6\) , (II), have been determined at 130 K. Compound (I) has a three-dimensional honeycomb substructure formed from head-to-tail hydrogen-bonded hydrogen tartrate anions and water molecules. The stacks of \(\pi\) -bonded quinolinium cations are accommodated within the channels and are hydrogen bonded to it peripherally. Compound (II) has a two-dimensional network structure based on pseudo-centrosymmetric head-to-tail hydrogen-bonded cyclic dimers comprising zwitterionic quinaldic acid species which are interlinked by tartaric acid molecules. + +Comment + +Tartaric acid is a relatively strong diprotic chiral \(\alpha\) -hydroxy acid ( \(pK_{a1} = 2.93\) and \(pK_{a2} = 4.23\) ) and, therefore, is potentially capable of forming both 1:1 and 1:2 proton-transfer salts with most Lewis bases. However, with stoichiometric control it is possible to selectively form 1:1 hydrogen tartrates, and the crystal structures of a large number of these 1:1 salts have been reported, particularly since these compounds usually have good crystal morphology, allowing structure determination by single-crystal X-ray analysis, which is often not possible with the parent Lewis base. Applications have been with drugs such as epinephrine (Carlström, 1973), dextromoramide (Bye, 1975), amosulalol (Furuya et al. , 1989), alprenolol (Głównka & Codding, 1989), phendimetrazine (Glaser et al. , 1994) and tolterodine (Košutić-Hulita & Žegarac, 2005), as well as natural products such as alkaloids, e.g. strychnine (Gould et al. , 1987), brucine (Smith, Wermuth & White, 2006), quinine (Ryttersgaard & Larsen, 2004), + +cinchonine (Puliti et al. , 2001), cinchonidine (Ryttersgaard & Larsen, 2003; Zhang et al. , 2003) and quincoridine (Kania et al. , 2004), and amino acids, e.g. L-alanine (Rajagopal et al. , 2002), L-proline (Subha Nandhini et al. , 2001), D-, L- and DL-histidine (Marchewska et al. , 2003; Rajagopal et al. , 2003; Johnson & Feeder, 2004 a,b,c ), and L-lysine (Debrus et al. , 2005). + +Because of the ready availability of L-(+)-tartaric acid, which has the confirmed 2R,3R absolute configuration, it has been very useful for both resolution and the crystallographic determination of absolute configuration in chiral molecular species, e.g. with the anticholinergic agent R-(−)-1,1-diphenyl-3-piperidinobutan-1-ol (Schjelderup et al. , 1990). More recently, its utility as an agent for the introduction of chirality in achiral organic compounds for the generation of crystalline materials with potentially useful non-linear optical properties has been explored (Aakeröy et al. , 1992; Fuller et al. , 1995; Marchewska et al. , 2003; Debrus et al. , 2005; Manivannan et al. , 2006). + +We have found that 1:1 stoichiometric interactions of the relatively strong carboxylic acids 5-sulfosalicylic acid (5-SSA) (Smith et al. , 2004) and 3,5-dinitrosalicylic acid (DNSA) (Smith, Wermuth, Healy & White, 2006) with a series of bicyclic heteroaromatic amines, including quinoline, tetra-hydroquinoline, 8-hydroxyquinoline, 8-aminoquinoline and + +Figure 1 + +The molecular configuration and atom-numbering scheme for the quinolinium cation, the hydrogen L-tartrate anion and the solvent water molecule in (I). Non-H atoms are shown as 50% probability displacement ellipsoids. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_12_pg1_pg1_repeat1.md b/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_12_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1da098c9eafc394869c19d948cefce43f0f9765a --- /dev/null +++ b/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_12_pg1_pg1_repeat1.md @@ -0,0 +1,135 @@ +nism of F protein activation, particularly in the absence of an attachment protein. HMPV F protein has also been shown to mediate cell-cell fusion (34) and virus-cell fusion (3) in the absence of the attachment G protein. Interestingly, syncytium formation by the HMPV F protein expressed alone in transfected cells was dependent on low pH (34). It is therefore possible that members of the Pneumovirinae subfamily have evolved distinct mechanisms of F protein activation compared to those of the Paramyxovirinae subfamily of paramyxoviruses. + +## ACKNOWLEDGMENTS + +This work was supported by grant SAF2006-07805, awarded to J.A.M., from the Ministerio de Educación y Ciencia. This laboratory participates in the “Virus-host” framework funded by the Comunidad de Madrid and in CIBER de Enfermedades Respiratorias, an initiative of ISCIII. We thank L. Roux (Geneva, Switzerland) for the pGEM-F and pGEM-HN plasmids, K.-K. Conzelmann (Munich, Germany) for the BSR-T7/5 cells, and S. Wharton and J. J. Skehel (London, United Kingdom) for the GB5 monoclonal antibody. We are also grateful for advice and comments from Teresa Corral, Paulino Gómez-Puertas, and Concepción Palomo. + +### REFERENCES + +1. Bagai, S., A. Puri, R. Blumenthal, and D. P. Sarkar. 1993. Hemagglutinin-neuraminidase enhances F protein-mediated membrane fusion of reconstituted Sendai virus envelope with cells. J. Virol. 67:3312–3318. + +2. Baker, K. A., R. E. Dutch, R. A. Lamb, and T. S. Jardetzky. 1999. Structural + +basis for paramyxovirus-mediated membrane fusion. Mol. Cell 3:309–319. + +3. Biacchesi, S., M. H. Skiadopoulos, L. Yang, E. W. Lamirande, K. C. Tran, B. R. Murphy, P. L. Collins, and U. J. Buchholz. 2004. Recombinant human metapneumovirus lacking the small hydrophobic SH and/or attachment G glycoprotein: deletion of G yields a promising vaccine candidate. J. Virol. 78:12877–12887. + +4. Buchholz, U. J., S. Finke, and K.-K. Conzelmann. 1999. Generation of + +bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter. J. Virol. 73:251–259. + +5. Collins, P. L., and J. E. Crowe. 2007. Respiratory syncytial virus and metapneumovirus, p. 1601–1646. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 5th ed. Lippincott Williams and Wilkins, Philadelphia, PA. + +6. Connolly, S. A., and R. A. Lamb. 2007. Paramyxovirus fusion: real-time + +measurement of parainfluenza virus 5 virus-cell fusion. Virology 355:203– + +212. + +7. Crim, R. L., S. A. Audet, S. A. Feldman, H. S. Mostowski, and J. A. Beeler. + +2007. Identification of linear heparin-binding peptides derived from human respiratory syncytial virus fusion glycoprotein that inhibit infectivity. J. Virol. 81:261–271. + +8. Deng, R., Z. Wang, P. J. Mahon, M. Marinello, A. Mirza, and R. M. Iorio. + +1999. Mutations in the Newcastle disease virus hemagglutinin-neuramini-dase protein that interfere with its ability to interact with the homologous F protein in the promotion of fusion. Virology 253:43–54. + +9. Elroy-Stein, O., T. R. Fuerst, and B. Moss. 1989. Cap-independent translation of mRNA conferred by encephalomyocarditis virus 5 sequence improves the performance of the vaccinia virus/bacteriophage T7 hybrid expression system. Proc. Natl. Acad. Sci. USA 86:6126–6130. + +10. Feldman, S. A., S. Audet, and J. A. Beeler. 2000. The fusion glycoprotein of + +human respiratory syncytial virus facilitates virus attachment and infectivity via an interaction with cellular heparan sulphate. J. Virol. 74:6442–6447. + +11. Garćıa-Barreno, B., C. Palomo, C. Peñas, T. Delgado, P. Perez-Breña, and + +J. A. Melero. 1989. Marked differences in the antigenic structure of human respiratory syncytial virus F and G glycoproteins. J. Virol. 63:925–932. + +12. González-Reyes, L., M. B. Ruiz-Argüello, B. Garćıa-Barreno, L. Calder, J. A. López, J. P. Albar, J. J. Skehel, D. C. Wiley, and J. A. Melero. 2001. Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion. Proc. Natl. Acad. Sci. USA 98:9859–9864. + +13. Heminway, B. R., Y. Yang, Y. Tanaka, M. Panin, Y. T. Huang, and M. S. + +Galinski. 1995. Role of basic residues in the proteolytic activation of Sendai virus fusion glycoprotein. Virus Res. 36:15–35. + +14. Ito, M., M. Nishio, H. Komada, Y. Ito, and M. Tsurudome. 2000. An amino + +acid in the heptad repeat domain 1 is important for the hemagglutininneuraminidase-independent fusing activity of simian virus 5 fusion protein. J. Gen. Virol. 81:719–727. + +15. Karron, R. A., D. A. Buonagurio, A. F. Georgiu, S. S. Whitehead, J. E. Adamus, M. L. Clements-Mann, D. O. Harris, V. B. Randolph, S. A. Udem, B. R. Murphy, and M. S. Sidhu. 1997. Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant. Proc. Natl. Acad. Sci. USA 94:13961–13966. + +16. Kido, H., M. Murakami, K. Oba, Y. Chen, and T. Towatari. 1999. Cellular + +proteinases trigger the infectivity of the influenza A and Sendai virus. Mol. Cell 9:235–244. + +17. Klenk, H.-D., and W. Garten. 1994. Host cell proteases controlling virus + +pathogenicity. Trends Microbiol. 2:39–43. + +18. König, P., K. Giesow, K. Schuldt, U. J. Buchholz, and G. M. Keil. 2004. A + +novel protein expression strategy using recombinant bovine respiratory syncytial virus (BRSV): modifications of the peptide sequence between the two furin cleavage sites of the BRSV fusion protein yield secreted proteins, but affect processing and function of the BRSV fusion protein. J. Gen. Virol. 85:1815–1824. + +19. Lamb, R. A. 1993. Paramyxovirus fusion: a hypothesis for changes. Virology + +197:1–11. + +20. Lamb, R. A., R. G. Paterson, and T. S. Jardetzky. 2006. Paramyxovirus + +membrane fusion: lessons from the F and HN atomic structures. Virology 344:30–37. + +21. Lamb, R. A., and T. S. Jardetzky. 2007. Structural basis of virus invasion: lessons from paramyxovirus F. Curr. Opin. Struct. Biol. 17:427–436. + +22. Lavillette, D., M. Maurice, C. Roche, S. J. Russell, M. Sitbon, and F.-L. + +Cosset. 1998. A proline-rich motif downstream of the receptor binding domain modulates conformation and fusogenicity of murine retroviral envelopes. J. Virol. 72:9955–9965. + +23. Leyrer, S., M. Bitzer, U. Lauer, J. Kramer, W. J. Neubert, and R. Sedlmeier. 1998. Sendai virus-like particles devoid of haemagglutinin-neuraminidase protein infect cells via the human asialoglycoprotein receptor. J. Gen. Virol. 79:683–687. + +24. McGuinnes, L. W., and T. G. Morrison. 2006. Inhibition of receptor binding + +stabilizes Newcastle disease virus HN and F protein-containing complexes. J. Virol. 80:2894–2903. + +25. Melero, J. A. 2007. Molecular biology of human respiratory syncytial virus, p. 1–42. In P. A. Cane (ed.), Respiratory syncytial virus. Perspectives in medical virology, vol. 14. Elsevier, Amsterdam, The Netherlands. + +26. Melikyan, G. B., R. M. Markosyan, H. Hemmati, M. K. Delmedico, D. M. + +Lambert, and F. S. Cohen. 2000. Evidence that the transition of HIV-1 gp41 into a six helix bundle, not the bundle configuration, induces membrane fusion. J. Cell Biol. 151:413–423. + +27. Paterson, R. G., C. J. Russell, and R. A. Lamb. 2000. Fusion protein of the + +paramyxovirus SV5: destabilizing and stabilizing mutants of fusion activation. Virology 270:17–30. + +28. Ruiz-Argüello, M. B., L. González-Reyes, L. J. Calder, C. Palomo, D. Martin, M. J. Saiz, B. Garćıa-Barreno, J. J. Skehel, and J. A. Melero. 2002. Effect of proteolytic processing at two distinct sites on shape and aggregation of an anchorless fusion protein of human respiratory syncytial virus and fate of the intervening segment. Virology 298:317–326. + +29. Ruiz-Argüello, M. B., D. Martıń, S. A. Wharton, L. J. Calder, S. R. Martin, O. Cano, M. Calero, B. Garćıa-Barreno, J. J. Skehel, and J. A. Melero. 2004. Thermostability of the human respiratory syncytial virus fusion protein before and after activation: implications for the membrane-fusion mechanism. J. Gen. Virol. 85:3677–3687. + +30. Russell, C. J., T. S. Jardetzky, and R. A. Lamb. 2001. Membrane fusion + +machines of paramyxoviruses: capture of intermediates of fusion. EMBO J. 20:4024–4034. + +31. Russell, C. J., K. L. Kantor, T. S. Jardetzky, and R. A. Lamb. 2003. A + +dual-functional paramyxovirus F protein regulatory switch segment: activation and membrane fusion. J. Cell Biol. 163:363–374. + +32. Scheid, A., and P. W. Choppin. 1974. Identification of biological activities of + +paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive precursor protein of Sendai virus. Virology 57:475–490. + +33. Schmidt, U., J. Beyer, U. Polster, L. J. Gershwin, and U. J. Buchholz. 2002. Mucosal immunization with live recombinant bovine respiratory syncytial virus (BRSV) and recombinant BRSV lacking the envelope glycoprotein G protects against challenge with wild-type BRSV. J. Virol. 76:12355–12359. + +34. Schowalter, R. M., S. E. Smith, and R. E. Dutch. 2006. Characterization of + +human metapneumovirus F protein-promoted membrane fusion: critical roles for proteolytic processing and low pH. J. Virol. 80:10931–10941. + +35. Segawa, H., T. Yamashita, M. Kawakita, and H. Taira. 2000. Functional + +analysis of the individual oligosaccharide chains of Sendai virus fusion protein. J. Biochem. 128:65–72. + +36. Stone-Hulslander, J., and T. G. Morrison. 1997. Detection of an interaction + +between the HN and F proteins in Newcastle disease virus-infected cells. J. Virol. 71:6287–6295. + +37. Tanabayashi, K., and R. W. Compans. 1996. Functional interaction of + +paramyxovirus glycoproteins: identification of a domain in Sendai virus HN which promotes cell fusion. J. Virol. 70:6112–6118. + +38. Techaarpornkul, S., N. Barretto, and M. E. Peeples. 2001. Functional anal- diff --git a/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c890dc00f65a10a52ebc548723f87a1cc5b01aec --- /dev/null +++ b/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,71 @@ +![](figure) + +A + +F_{RSV} +SP F2 pep27 FP HRA F1 HRB TM CT + +F_{SeV} +SP F2 FP HRA F1 HRB TM CT + +R109 R136 +R116 + +B + +Trypsin - +Trypsin + + +F_{RSV} F_{RSV} + G F_{SeV} F_{SeV} + HN + +C + +Fusion (%/wt) + +F_{RSV} F_{RSV} + G +- Trypsin + Trypsin + +Fusion (%/wt) + +F_{SeV} F_{SeV} + HN +- Trypsin + Trypsin[^inferred] + +![](figure) + +A + +F_{RSV} +SP F2 pep27 FP HRA F1 HRB TM CT + +F_{SeV} +SP F2 FP HRA F1 HRB TM CT + +R109 R136 +R116 + +B + +Trypsin - +Trypsin + + +F_{RSV} F_{RSV} + G F_{SeV} F_{SeV} + HN + +C + +Fusion (%/wt) + +F_{RSV} F_{RSV} + G +- Trypsin + Trypsin + +Fusion (%/wt) + +F_{SeV} F_{SeV} + HN +- Trypsin + Trypsin[^inferred] + +FIG. 1. RSV and SeV fusion proteins have different requirements for cell-cell fusion. (A) Schematic diagram of RSV fusion (FRSV) and SeV fusion (FSeV) proteins. The three principal hydrophobic regions found in paramyxovirus F proteins are shown in black: the N-terminal signal peptide (SP), the fusion peptide (FP), located adjacent to the cleavage site at the N terminus of F1, and the C-terminal transmembrane region (TM). Heptad repeat sequences HRA and HRB (hatched boxes) are located adjacent to the FP and TM regions, respectively. Cleavage sites of FRSV (site I, R109, and site II, R136) and FSeV (R116) are indicated by arrows. Cleavage results in the formation of disulfide-linked F2 and F1 polypeptides, and in the case of FRSV, cleavage at both sites results in the removal of the intervening segment pep27, shown in light gray. + +(B) BSR-T7/5 cells were cotransfected in microchamber culture slides with 0.25 \(\mathrm{g}\) of pTM1 plasmids encoding RSV or SeV F genes and 0.25 \(\mathrm{g}\) pTM1-G or pTM1-HN plasmids, as indicated, or 0.25 \(\mathrm{g}\) empty vector pTM1 (not indicated). The transfection mixture was removed 7 h posttransfection and cells were incubated in serum-free medium with \(()\) or without \((-)\) trypsin. Cells were fixed and immunostained as indicated in Materials and Methods. Immunofluorescence of cells transfected with the empty pTM1 plasmid was conducted in parallel, and the absence of fluorescence confirmed specific antibody staining (data not shown). (C) BSR-T7/5 cells were transfected in 48-well plates with plasmids encoding RSV or SeV genes. BHK cells were simultaneously transfected with a plasmid encoding the luciferase gene (pTM1-Luc). At 7 h posttransfection, BHK cells were detached using 1 mM EDTA, resuspended at a density of \(110^{6}\) cells/ml in serum-free medium, and overlaid at a 1:1 ratio onto BSR cells, either in the presence or absence of trypsin. At 30 h posttransfection (or 48 h posttransfection for experiments involving FRSV), cells were lysed and analyzed for luciferase activity. Results (relative light units) are expressed as a percentage of the wild-type (wt) fusion (FSeV plus HN plus trypsin, or FRSV plus G plus trypsin), with background activity subtracted (determined by overlaying BHK cells transfected with pTM1-Luc onto BSR cells transfected with the empty pTM1 plasmid). Mean values from three independent experiments are shown. + +forms in approximately equal proportions. A band migrating at a lower molecular weight than F0 was observed for the mutant Fc\(\_103-117\). Although the identity of this band has not been thoroughly investigated, it may represent the F0 precursor of the Fc\(\_103-117\) mutant, which lacks an N-glycosylation site that has previously been shown to be used in the Z strain of SeV F protein (N104) (35). When trypsin was added to the medium of the transfected cells (Fig. 3B, lower panel), cleavage of the F0 precursor of both wild-type FSeV and F_RKR to F1 was clearly enhanced. In contrast, only a slight increase in F0 processing was detected when trypsin was added to cells expressing the Fc mutant. However, the extent of F0-to-F1 cleavage was enhanced by trypsin in all four FSeV mutants containing both FRSV cleavage sites, and Fc_103–130 appeared fully cleaved to F1 in the presence of trypsin. Thus, insertion of an FRSV cleavage site II in the SeV F protein increases the extent of cleavage at this site in the absence of trypsin. This cleavage is further enhanced by + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..49ae348792a131e6091ee2a6ebc5a267c71ca12b --- /dev/null +++ b/outputs/multi_column/05aa71fa77e07bccb443ef4fd28dde3ecfd6_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,7 @@ +![](figure) + +![](figure) + +FIG. 4. Insertion of the RSV F cleavage site II in SeV F leads to trypsin-independent syncytium formation. BSR-T7/5 cells growing in microchamber wells were cotransfected as previously described with 0.25 \(\mathrm{g}\) pTM1-F_RKR or pTM1-Fc mutants and 0.25 \(\mathrm{g}\) pTM1-HN plasmid \((\text{HN})\) or 0.25 \(\mathrm{g}\) empty pTM1 vector \((-\text{HN})\). The transfection mixture was removed 7 h posttransfection, and cells were incubated in serum-free medium with \(()\) or without \((-)\) trypsin. Cells were fixed 32 h posttransfection and subjected to immunostaining as described in Materials and Methods. + +Fc_103–110 mutant forms syncytia in the absence of HN. However, the nature and/or length of the intervening residues between the two cleavage site does appear to influence fusion to a greater extent in the absence of HN, since Fc_103–117 formed large syncytia whereas Fc\(\_103-117\) formed only small syncytia without HN. In the absence of HN coexpression, three mutants containing both FRSV cleavage sites (Fc_103–110, Fc_103–117, and Fc_103–130) produced fusion activity in the luciferase reporter gene assay in the presence of trypsin (Fig. 6B). As observed in the syncytium formation assay, Fc did not produce significant fusion in the absence of HN. Fc\(\_103-117\) also failed to produce HN-independent fusion, reflecting the small syncytia produced by this mutant in the absence of an attachment protein, in spite of the fact that it contains both FRSV cleavage sites. Enhanced membrane fusion in the absence of HN by the double cleavage site mutants paralleled the increase in F0to-F1 cleavage by trypsin, compared with single site mutants (Fig. 3B). However, no precise quantitative correlation between F0 processing and membrane fusion activity in the absence of HN could be found. For instance, while Fc\(\_103-117\) was highly susceptible to trypsin cleavage, this mutant was poorly active in both membrane fusion assays (Fig. 6). Furthermore, although Fc_103–130 was cleaved by trypsin more efficiently than Fc_103–110 or Fc_103–117 (Fig. 3B), it did not produce larger syncytia or induce greater luciferase activity in the absence of HN (Fig. 6). The Fc_103–117 mutant produced the greatest fusion activity in the absence of the HN protein and was subjected to a dose-response fusion assay in the presence of trypsin and compared with Fc (Table 1). Increasing quantities of DNA were used to transfect BSR cells, and the corresponding increase in cell surface expression was determined by flow cytometry. An average fusion index was subsequently calculated from the fusion and expression data. While increasing expression of Fc did not enhance fusion, a dose response of fusion was seen for Fc_103–117, confirming the ability of this double cleavage site mutant to fuse cells in the absence of HN. The fusion index estimated for Fc_103–117 was 0.72, compared to 0.08 for the Fc mutant and 1.0 for wild-type F (FSeV coexpressed with HN in the presence of trypsin). However, higher expression levels of Fc_103–117 were required in the luciferase reporter gene assay, compared to the syncytium formation assay, in order to observe a level of HN-independent cell-cell fusion comparable to the wild type. This may reflect differences in the requirements of the two assays. For instance, the presence of F protein in both target and donor cells in the syncytium formation assay may facilitate cell-cell fusion with respect to the reporter gene assay, in which F protein is present only in the donor BSR cells. Furthermore, the reporter gene assay involves the interaction between two distinct populations of cells and may depend to a greater extent on the attachment ability of the mutated F proteins. Coexpression of the attachment G protein fails to restore the reduced fusogenic capacity of RSV F cleavage site mutants. It has previously been shown that cleavage at both sites I and II is a requirement for fusion of the FRSV protein, expressed in transfected cells in the absence of the attachment G protein. Mutations of FRSV cleavage site I abrogated syncytium formation in the absence of trypsin, whereas deletion of FRSV cleavage site II prevented syncytium formation, even in the presence of trypsin (12, 45). In light of our findings that insertion of FRSV cleavage site I in FSeV led to syncytium formation by FSeV in the absence of HN, we aimed to determine whether coexpression of RSV G protein with FRSV cleavage site mutants would restore cell-cell fusion. A series of FRSV mutants (Fig. 7A), which have been previously described (12, 28, 29), were subcloned in the pTM1 plasmid. These mutations included changes in cleavage site I (RARR) to produce the F_R108/109N mutant (RANN) or deletion of four basic residues in cleavage site II (KKRKRR), resulting in the \(\mathrm{F}\_131-134\) mutant (12). Further deletions in F_R108/109N resulted in the RSV \(\mathrm{F}\_108-120\text{and F}\_108-132\) mutants (28, 29). All mutant proteins were expressed at the cell surface at a level comparable to FRSV (Fig. 7B), with the exception of the cleavage site II mutant \(\mathrm{F}\_131-134\), which diff --git a/outputs/multi_column/05eac72b90295dbb76786d1fe5e2fe0db27d_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/05eac72b90295dbb76786d1fe5e2fe0db27d_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..08ebce7714c524336ffeb5116d59d544f6b0a42c --- /dev/null +++ b/outputs/multi_column/05eac72b90295dbb76786d1fe5e2fe0db27d_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +cocaine bolus (Howell et al., 2001, 2002, 2009). Cocaine HCL was supplied by the National Institute on Drug Abuse (Research Technology Branch, Research Triangle Park, NC) and dissolved in 0.9% saline. Throughout this study the infusion rate and volume were held constant at 15 ml/min and 4 ml, respectively. This dose is expressed as the salt form. + +### 2.6. Spatial motion analysis + +Translation and rotation data were determined during each of the three scans and analyzed separately. The maximum translation and rotation from one acquisition to the next across the entire time series and across all three scans was compared to specific criteria (translations to one half the size of the voxel size or 0.75 mm and rotations to \(1.5^{\circ})\) via a one-sample t-test. Furthermore, two-way RM ANOVA was utilized to compare the maximum, mean, and the variability of translational and rotational motion across axis and scan condition. For these analyses realignment parameters were transformed by taking the absolute value of the difference from one acquisition to the next and therefore represent absolute motion across acquisitions. Graphical presentation of all data depicts mean ± SEM, and any points without error bars indicate instances in which the SEM is encompassed by the data. All graphical data presentations were created using GraphPad Prism 4 (La Jolla, CA), all statistical tests were performed using SigmaStat 3 (San Jose, CA), and significance was arbitrated at a p < 0.05. + +## 2.6.1. fMRI data analysis + +Analyses were carried out using the standard image analysis package Statistical Parametric Mapping version 5 (SPM5—Wellcome Trust Center for Neuroimaging, London, UK) supplemented by custom software written in the matrix based programming environments IDL (ITT, Boulder, CO) and MATLAB (MathWorks, Natick, MA). Preprocessing of the images was initiated via placement of both the anatomical and functional images in AC-PC alignment and in gross registration to one another. Time series realignment using a 6 parameter rigid body algorithm (Cox and Jesmanowicz, 1999; Woods et al., 1993) to reduce the influence of any subject motion was then carried out. Concurrently, field inhomogeneity data were used to correct any geometric distortions in the EPI images using an automated algorithm that takes into account the interaction between motion and inhomogeneities and has been shown to result in an improved coregistration between EPI and T1 images (Cox and Jesmanowicz, 1999; Hutton et al., 2002). Anatomical data were then segmented into gray matter, white matter, and bias corrected images. Functional data were then spatially normalized to the bias corrected (intensity normalized) anatomical images and spatially smoothed using a kernel with a full width at half max equal to two times the native resolution of the image (i.e. 3 mm). Linear drift was accounted for by global normalization across the time series and high-pass filtering. Whole brain analysis was carried out on a pixel by pixel basis using a parametric general linear statistical model. This analysis was confined to gray matter pixels using a custom generated mask to exclude any white matter or ventricle pixels that was applied to the data prior to statistical analysis. Motion parameters were used as covariates within this model to remove the influence of subject motion on the subsequent results. The general linear model fit was based on a flexible boxcar design using the canonical hemodynamic response function and corrections for multiple comparisons were carried out such the probability of a type I error was maintained at 5% (Genovese et al., 2002). Finally, the timecourse of the MR signal was determined in the voxel that showed the local maximum correlation to presentation of the visual stimulus (in visual cortex) or administration of cocaine (in the anterior cingulate). The signal measured under each condition was averaged across all three subjects. Graphical data presentations were created using GraphPad Prism 4 (La Jolla, CA). + +## 3. Results + +Under the conditions employed, rhesus monkeys could be reliably acclimated to undergo fMRI scans while awake. The integrity of the imaging data necessitated that subjects were minimally stressed and near motionless. To objectively assess the effectiveness of the training procedure in minimizing any stress to the subject, physiological and endocrine measurements were taken, in fully acclimated subjects, over 2 h sessions in either the custom fMRI apparatus or in a standard primate chair (with the exception of the respiratory rate data—see Section 2). In each condition, physiological measurements were taken over three sessions whereas endocrine measurements were taken over two sessions. In the custom fMRI cradle, one-way RM ANOVA reveal no main effect of heart rate (F2,2 = 0.295; p = 0.760), respiratory rate (F2,2 = 2.027; p = 0.212), blood pressure (F2,2 = 0.051; p = 0.951), and temperature (F2,2 = 5.528; p = 0.096) as a function of session. The powers of these tests were 0.051, 0.155, 0.051, and 0.214, respectively. In the primate chair (or custom apparatus without head restraint for respiratory rate data), heart rate (F2,2 = 2.537; p = 0.194), respiratory rate (F2,2 = 2.501; p = 0.125), blood pressure (F2,2 = 2.154; p = 0.213), and temperature (F2,2 = 0.967; p = 0.454) were not significantly different as a function of session. The powers of these tests were 0.177, 0.586, 0.158, and 0.051, respectively. Data from each session were then averaged. A two-way RM ANOVA was then used to determine if there were significant differences as a function of the apparatus used or the time spent in a given apparatus. Heart rate (F2,1 = 0.074; p = 0.811), respiratory rate (F2,1 = 0.342; p = 0.618), blood pressure (F2,1 = 1.875; p = 0.304), rectal temperature (F2,1 = 0.002; p = 0.968), and plasma cortisol levels (F2,1 = 1.854; p = 0.306) did not significantly differ by condition. The powers of these tests were 0.058, 0.085, 0.096, 0.058, and 0.095, respectively. Furthermore, there was no main effect of time spent in the apparatus for heart rate (F2,3 = 0.395; p = 0.762), respiratory rate (F2,3 = 3.156; p = 0.107), blood pressure (F2,3 = 1.152; p = 0.402), rectal temperature (F2,3 = 0.402; p = 0.757), or plasma cortisol levels (F2,4 = 2.230; p = 0.155). The powers of these tests were 0.050, 0.636, 0.066, 0.051, and 0.234, respectively. Mean basal plasma cortisol levels were, prior to research personnel entering the colony, were + +22.925 ± 2.764 and 26.313 \(\pm4.202\mathrm{g}/\)dl on the days when measurements were subsequently collected in the custom cradle or the commercial chair, respectively. Analysis via a paired t-test revealed that basal plasma cortisol levels did not differ across these different days \((\mathrm{t}_{3}=-3.388\); p = 0.148). The power of this test was 0.230. In addition to a stable physiology, good quality fMRI data requires minimal subject motion. Fig. 4 shows transformed realignment parameters across the three translational and rotational axes, assuming rigid body motion, averaged across the three subjects. These data are summarized in Table 1 as expressed by the maximum, mean, and standard deviation of the motion from acquisition to acquisition in each axis. One-sample t-tests revealed that translational and rotational movements were significantly less (p < 0.05) than criterion for all axes and conditions except Z-axis translations \((\mathrm{t}_{3}=-3.066\); p = 0.092) and X-axis rotations \((\mathrm{t}_{3}=-1.537\); p = 0.264) during visual stimulation. Two-way RM ANOVA revealed that, for the maximum translational motion from scan to scan, there was no main effect of axis (X, Y, Z; F2,2 = 2.500; p = 0.197) or condition (no stimulation, visual stimulation, cocaine; F2,2 = 2.257; p = 0.221) and no significant interaction (F2,4 = 0.901; p = 0.507). The powers of these tests were 0.174, 0.153, and 0.050, respectively. Furthermore, there was no main effect of axis (F2,2 = 0.156; diff --git a/outputs/multi_column/06032fa18b312e3f7186a1cbd6c11cc4b1a4_page_13_pg1_pg1_repeat1.md b/outputs/multi_column/06032fa18b312e3f7186a1cbd6c11cc4b1a4_page_13_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fe6bca4a4ace60028a8adc8756a7ab2d9ec9508a --- /dev/null +++ b/outputs/multi_column/06032fa18b312e3f7186a1cbd6c11cc4b1a4_page_13_pg1_pg1_repeat1.md @@ -0,0 +1,61 @@ +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Fig. 18. Failure case illustration. First Row: we test our method in wide baseline cases of light field, segmentation tends to inconsistent due to large view point changes. Second Row: The visual results of the non-Lambertian cases. Our method discovers correct object boundaries, but mistakenly separates objects due to incorrect depth matches. + +## 7 APPLICATIONS + +Segmentation is a starting point for many processes in image manipulation and computer vision. In the following we highlight several applications of our light field segmentation method. + +### 7.1 User-guided Object Segmentation. + +Like most 2D and video segmentation methods, our method segments the light field into regions of consistent appearance, but not into semantic objects. However with a simple user interface, we can can manually select multiple regions that comprise a single object. Examples of this user-guided object segmentation are shown in Fig. 19. + +### 7.2 Light Field Flattening + +Image flattening refers to the suppression of texture detail while preserving strong scene edges and overall image structure. Here, we extend an existing 2D method [Bi et al. 2015] to 4D. Specifically, we take into consideration the \(L_{1}\) sparsity in spatial slices, angular patches as well as the 4D light field segmentation, and jointly minimize the pixel variation and approximation error as detailed in the following. + +Spatial Term. \(\mathbf{f}_{i}\) is the \(Lab\) feature vector of pixel \(p_{i}\). + +\[\begin{aligned} E_{l}&=\sum_{ip_{j}\in}\sum_{N_{h}(}w_{ij}\Vert L(i)-L(j)\Vert_{1}, \\ p_{i}) \end{aligned}\] (24) + +where \(N_{h}(p_{i})\) is a spatial local \(h\times h\) patch. \(w_{ij}\) is the affinity between pixel \(p_{i}\text{and}p_{j}\). Here, we simply use Euclidean distance with a normalization function. + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Fig. 19. User guided object segmentation. Regions comprising a single object are selected by a user. The regions themselves are not manually altered. + +Angular Term. We prefer a uniform intensity values over simple angular patches of the light field, and smooth exposure variation in different spatial slices. Similar to Eqn. 24, we formulate our angular flattening term as + +\[\begin{aligned} E_{a}&=\sum_{ip_{j}\in}\sum_{N_{a}(}w_{ij}\Vert L(i)-L(j)\Vert_{1}, \\ p_{i}) \end{aligned}\] (25) + +where \(N_{a}p_{i}\) is the angular patch that \(p_{i}\) lies in. + +Segmentation Term. The segmentation provides extra cues to include more pixels for avoiding the influence of shading, reflectance or noise. + +\[E_{s}=\sum_{p_{i}\in s_{k}}\sum_{p_{j}\in s_{k}}w_{ij}\Vert L(i)-L(j)\Vert_{1},\] (26) + +Data Fidelity Term. To avoid trivial solution, smoothed light field should be similar to original light field, which is formulated as, + +\[E_{d}=\sum_{i}\Vert L(i)-L^{ini}(i)\Vert_{2},\] (27) + +where \(L^{ini}\) is original light field data. The overall objective function is the sum of those terms, + +\[E=E_{d}+\alpha E_{l}+\beta E_{a}+\gamma E_{s},\] (28) + +where \(\alpha,\beta,\gamma\) are weight parameters. Fig. 20 shows the results of the light field segmentation, where we then utilize the segmentation cue to remove fine details and preserve the main edges of the light field. In the example of Fig. 21, we visualize our light field segmentation, edge detection results and pencil sketching. We first utilize our light field segmentation for removing fine details of light field. Then, we apply conventional edge detection method [Dollár and Zitnick 2015] diff --git a/outputs/multi_column/06125479b00df48e91fe2fb616292d14116d_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/06125479b00df48e91fe2fb616292d14116d_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fc6d3df30deb54cd76575cef5c59b5863517ef70 --- /dev/null +++ b/outputs/multi_column/06125479b00df48e91fe2fb616292d14116d_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,40 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Protecting the Last Wild Bison + +Photo courtesy of Michelle McCarron + +Printed on Recycled Paper + +Take Action Be a Voice for Wild Buffalo! + +Tell Gov. Bullock to +Leave a Wild Legacy + +Montana Governor Steve Bullock has his sights set on the White House. Tell him you take the buffalo into the voting booth with you! Ask Gov. Bullock for a new decision with public involvement and comment to protect more year-round habitat for wild buffalo, including the south side of the Madison River on the Custer Gallatin National Forest, where hazing still takes place on cattle-free public land. + +He can order the Montana executive branch to start a public process and leave a legacy that this country can be proud of! Phone calls are best because they can't be ignored, but you can back your call up with an email. Call Gov. Bullock at (406) 444-3111 and email governor@mt.gov. Wild is the Way—Roam Free! + +Come volunteer and stand with wild buffalo! + +Get Involved & Volunteer! + +Contact BFC to learn about volunteering on the front lines, joining our summer outreach team, hosting video showings, distributing newsletters, and other ways you can spread the word to save the herds! Email info@buffalofieldcampaign.org or call (406) 646-0070. See all the details at buffalofieldcampaign.org/volunteer-with-us. + +Support BFC! + +Individuals like you contribute the majority of Buffalo Field Campaign's budget. All donations are tax deductible. Make a secure online contribution at BuffaloFieldCampaign.org or use the enclosed envelope to donate by mail. + +Stay Engaged! + +Visit BuffaloFieldCampaign.org for our complete Take Action page and to sign up for Updates from the Field. + +YouTube youtube.com/bfcmedia + +facebook.com/buffalowild + +instagram.com/buffalofieldcampaign + +twitter.com/BFC_WildBison + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_11_pg1_pg1_repeat1.md b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_11_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e017c4bad4bb84418d3b45ce03e7d367ce96e2a6 --- /dev/null +++ b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_11_pg1_pg1_repeat1.md @@ -0,0 +1,45 @@ +p. 331 et suiv.). Selon ces différentes modalités de lecture, les motifs bruts tireraient leur épingle du jeu au niveau de l’association qui les valorise le mieux. Le même processus se produit avec les intonations, les associations syllabiques et les constructions syntaxiques. On sait en effet que les phonèmes, la sémantique et le langage favorisent l’éclosion des subtilités à l’intérieur d’une grammaire générative (Chomsky, 1980). Les propositions graphiques évolueraient, elles aussi, sous forme de sémioses graphiques (Georges, 2015, pour gagner en lisibilité, en efficacité et en intelligibilité, sans chercher seulement à capter l’attention ou correspondre à une convention empreinte de superficialité. Dans la structure produite, le motif, tels une note de musique, une syllabe ou encore un oncle dans un système de parenté, prend ou conserve à un moment donné une signification et une fonction originale. Le substrat cognitif des graphismes ne saurait être ignoré et justifie l’intérêt que l’on se doit de porter au contenu et à l’organisation de l’ornementation. Les arbres stylistiques tendent à décliner l’ensemble des dispositifs + +Racine cognitive + +? + +? + +3 + +1 + +4 + +2 + +a usités. Leurs fabrications respectives peuvent reposer sur des principes sensiblement différents. + +## La méthode régressive + +Le principe initial de cette procédure est d’isoler l’ornementation la plus complexe en vue d’y associer des organisations de plus en plus simples. Du fait de cet ordre décroissant, la méthode est dite régressive (fig. 7). Cette opération revient à déterminer que les formes les plus complexes de décors ne sont pas des œuvres isolées, mais qu’elles sont liées à un niveau plus ou moins élevé d’accrétion de motifs sur une base commune. L’hypothèse d’une expression fantaisiste doit être écartée pour considérer un programme ornemental répondant à des règles précises. Un tel résultat justifie de revenir a posteriori sur le critère morphologique des bracelets (voir infra). Avant cela, il ressort que la structure seule des décors suffit pour proposer une classification, sans préjuger par ailleurs à ce stade d’une quelconque évolution d’ordre chronologique (voir infra). + +5 cm + +0 + +8 + +9 + +5 + +6 + +7 + +10 + +b + +![](figure) + +Fig. 7 – Arbre stylistique par méthode régressive : les séquences en projection plane orthogonale du type Clans dans l’extrême sud-est de la France. Branche 1 : dépôt de Lullin, Haute-Savoie (Oberkampf et coll., 1997, pl. 35, no 13); Br. 2 : dépôt de Pinerolo, Italie du Nord (Doro, 1973-1975, fig. 1); Br. 3-5 : dépôt de Clans, Alpes-Maritimes (Guébhard, 1910a ; Lagrand, 1976, fig. 2, nos 1, 2 et 22); Br. 6 : Cimiez ou Cannes, Alpes-Maritimes (Lagrand, 1968, pl. VII, no 2 et d’après les moulages conservés au MAN, no 22 546); Br. 7 : Montgros, Nice (Lagrand, 1968, pl. VII, no 5, d’après le moulage conservé au MAN, no 55 427); Br. 8 : Montgros, Alpes-Maritimes (d’après le moulage conservé au MAN, no 55 427); Br. 9 : Montgros (d’après le moulage conservé au MAN, no 55 427); Br. 10 : Montgros (Lagrand, 1968, pl. VII, no 4, d’après le moulage conservé au MAN, no 55 427); a et b : Cannes ou Cimiez, compositions intermédiaires entre les branches 5 et 7 (Lagrand, 1968, pl. VII, nos 1 et 3). + +Fig. 7 – Stylistic tree by regressive method: orthogonal sequences of Clans type in French Riviera. Branch 1: Lullin hoard, Haute-Savoie (Oberkampf and coll., 1997, pl. 35, no. 13); Br. 2: Pinerolo hoard, North Italy (Doro, 1973-1975, fig. 1); Br. 3-5: Clans hoard, Alpes-Maritimes (Guébard, 1910a; Lagrand, 1976, fig. 2, nos. 1, 2 and 22); Br. 6: Cannes or Cimiez, Alpes-Maritimes (Lagrand, 1968, pl. VII, no. 2 and adapted from the moldings, MAN, no. 22546); Br. 7: Montgros, Nice, Alpes-Maritimes (Lagrand, 1968, pl. VII, no. 5, adapted from the molding, MAN no. 55427); Br. 8: Montgros (adapted from the molding, MAN no. 55427); Br. 9: Montgros (adapted from the molding, MAN, no. 55427); Br. 10: Montgros (Lagrand, 1968, pl. VII, no. 4, adapted from the molding, MAN, no. 55427); a and b: Cannes or Cimiez [?],intermediate compositions between the branches 5 and 7 (Lagrand, 1968, pl. VII, nos. 1 and 3). diff --git a/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_18_pg1_pg1_repeat1.md b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_18_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..38e9d86ca18f0f327d802a859b378dfe534cfe48 --- /dev/null +++ b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_18_pg1_pg1_repeat1.md @@ -0,0 +1,5 @@ +pourraient se développer à la marge des panneaux répétitifs des branches 7 à 11 de l’arbre stylistique du style Bignan. Le phénomène du panneau unique ou répétitif signe un essoufflement du style Bignan au cours de sa large diffusion sous une forme plus simple. Cette phase se confronte à une recrudescence en graphismes complexes débutant à la toute fin du Bronze moyen dans un espace géographique plus méridional. Les bracelets du dépôt de Vinols regroupent ainsi des décors conti-nus simples avec des formes complexes en tripartition à panneau central long. Ces derniers incorporent quelques thématiques communes avec le style Bignan (Georges, 2007, fig. 123 et suiv.). Les branches 12 et 13 de l’arbre stylistique du style Bignan sont l’écho de cette tripartition continentale plus au nord à partir de la fin du XIVe siècle av. J.-C., au Bronze final. On y observe l’hybridation d’une structure de décor tripartite continentale avec des thèmes appartenant encore au style Bignan au sens le plus large de son expression. L’organisation tripartite existe en masse dans le Bassin parisien par les vallées de l’Yonne et de l’Aube au XIVe siècle. av. J.-C. (Rottier et al., 2012, p. 85-95). À la même époque et au siècle suivant, le style Poype montre un déplacement est-ouest de son centre de gravité et de ses graphismes, du début du Bronze final jusqu’au Bronze final IIb, sur plusieurs centaines de kilomètres (fig. 11A). Des déplacements ponctuels à plus longue distance interviennent en direction de l’Europe centrale (fig. 11B). Ces occurrences ont des liens étroits avec les branches initiales 11 et 12 des décors végétalisés du Bronze final IIa (voir supra et fig. 8). Le premier style est documenté dans des tombes sur le piémont italien et à Chusclan, dans le Gard, alors que le style plus évolué figure dans des dépôts. Par la suite, le prélèvement partiel ou la soustraction totale des paires de bracelets à la mort de la défunte se renforce durant la phase initiale et surtout moyenne du Bronze final en pourtour de l’arc Alpin (Verger, 1992 ; Georges, 2015). Ces exclusions entraînent des dépôts avec des bracelets brisés à foison, comme à Larnaud, dans le Jura (Simon-Millot, 1998), et Amboise, dans le Val de Loire (Cordier, 2002). Le recyclage abondant comprend l’interpénétration des styles et prouve la généralisation de la pratique au nord et à l’ouest des Alpes durant l’étape moyenne du Bronze final. Le démantèlement est incontestable avec les résidus de crémation munis d’un seul bracelet, voire moins (Verger, 1992) ou dans le cas d’une unique jambière retrouvée en inhumation (Zylmann, 2009) Avant cela, on observe la soustraction encore très partielle de bracelets des sépultures durant le début du Bronze final dans les vallées de l’Yonne et de l’Aube (Rottier et al., 2012, p. 85-95). Les apparitions exclusives dans des « dépôts à bracelets » pour le style Clans suggèrent une exclusion des sépultures plus drastiques dès le début du Bronze final. Le dépôt de Vinols illustre le phénomène dès l’extrême fin du Bronze moyen ou au début du Bronze final au XIVe siècle av. J.-C., nonobstant les occurrences similaires retrouvées en tombe ou dans des grottes au caractère sépulcral plus ou moins affirmé dans le Sud-Est du Massif central (Roudil, 1972, fig. 37-39, 41-42, 57 et 61 ; Georges, 2007, fig. 123 et suiv.). Durant le Bronze moyen atlantique, le fonctionnement des dépôts à bracelets est ancien, mais il ne regroupe pas de paires rendues visibles à partir des décors comme dans le dépôt précédemment cité. La présente modélisation cartographique recouvre ces différences régionales de traitements des bracelets et les constellations spatiales témoignent de dynamiques spatiotemporelles de grandes ampleurs. La corrélation entre la localisation des occurrences avec la succession des branches des arbres stylistiques apporte son lot de précision quant au détail des distributions. + +## L’étude comparée des arbres stylistiques + +La figure 11 montre essentiellement des arbres stylistiques jouissant de développements parallèles autonomes, mais cela ne veut pas dire que les hybridations n’existent pas (voir supra); il arrive aussi que des styles différents se télescopent. Les dépôts haut-savoyard et piémontais de Lullin et Pinerolo réunissent à la fois des bracelets de type Clans et Poype (fig. 11). Au travers de branches contigües ou presque, les arbres stylistiques replacent la relation peu ou prou synchrone au cours du Bronze final I dans un contexte plus large (fig. 7, br. 1-2 ; fig. 8, br. 8 et 10 et 11a). Le style Clans s’est développé à l’arrivée du type Poype à l’ouest des Alpes et peut-être en réaction à celuici, à une époque pendant laquelle le style Poype gagne en exubérance, soit au niveau des branches médianes de l’arbre stylistique. Le style Bignan n’a d’étroites relations avec les bracelets du Lüneburg au Nord de l’Allemagne qu’au niveau de ses branches tardives (Laux, 1971). Cette homogénéisation n’intervient donc que tardivement, à l’occasion d’un semblant d’unité culturelle antérieurement et diversement décrite de l’Atlantique nord à la baltique (Buttler, 1963 ; Gabillot, 2005, p. 51). Elle coïncide avec l’Ornament Horizon, qui inclut les bracelets à ornementations complexes au Sud de l’Angleterre à partir de la transition entre le Bronze moyen évolué et le début du Bronze final (Rowlands, 1971). Les décors de Lüneburg de cette dernière période se prêtent manifestement et favorablement à une classification sur un mode régressif (Laux, 1982, fig. 3). Par ailleurs, les bracelets continentaux d’Europe centrale du Bronze moyen doivent également bénéficier d’un classement stylistique, cette fois-ci par la méthode progressive, sans avoir d’accointances avec le style Bignan (études en cours). Ces dernières observations n’ont pas vocation à expliquer les processus anthropologiques en cause, les arbres stylistiques visent seulement à retracer l’image précise de la construction de normes ornementales. La base documentaire justifie maintenant de s’interroger sur la nature sociale des différents programmes décoratifs. Dans cette voie, les vues surfaciques, qui n’étaient au départ qu’un stratagème expérimental nécessaire à l’élaboration de ces arbres stylistiques, vont trouver des correspondances directes dans la documentation archéologique. diff --git a/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_20_pg1_pg1_repeat1.md b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_20_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1b7232d596ec452995a4eb90feda1ca0132571d6 --- /dev/null +++ b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_20_pg1_pg1_repeat1.md @@ -0,0 +1,11 @@ +# L’APPORT DES TRAMES GÉOMÉTRIQUES SUR OBJETS ARCHÉOLOGIQUES + +# Le Néolithique et le Chalcolithique + +Les décors chasséens du IVe millénaire av. J.-C., gravés sur les coupes à socles (vases-supports) et coupes à grand marli mais pas seulement, comportent des trames géométriques orthogonales qui rappellent les vues surfaciques réalisées à partir de décors sur bracelets. Un tableau synoptique à double entrée distingue d’une part, de gauche à droite, les modes de remplissage et d’autre part, de haut en bas, les trames simples à complexes (fig. 12). Cette lecture ordonnée s’applique aussi pour l’Ouest de la péninsule Ibérique à partir des plaques gravées retrouvées dans des contextes funéraires du Chalcolithique à la fin du IVe et au tout début du IIIe millénaire av. J.-C. (fig. 13). La comparaison des deux tableaux montre la réduction de la gamme des formes simples au profit des formes complexes du IVe au début du IIIe millénaire. Au cours de la première moitié du IIIe millénaire, le récapitulatif des trames présentes sur les stèles gravées de Sion fait apparaître une dichotomie nouvelle entre les décors en damier et ceux à lignes obliques (fig. 14). Les premiers évoquent clairement l’héritage vivace en ce lieu d’une tradition néolithique, alors que les seconds à base losangique sont promis à un bel avenir à l’âge du Bronze. Tout en conservant un étroit rapport avec le Chalcolithique ibérique plus précoce, le Chalcolithique valaisan distille ainsi des trames vestimentaires innovantes dans le deuxième quart du millénaire suivant (Harrison et Heyd, 2007). Du Néolithique au Chalcolithique, les trames montrent une grande cohérence avec des évolutions très sensibles dont il est possible de suivre le devenir à l’âge du Bronze. + +## L’âge du Bronze + +Les trames géométriques se maintiennent sous des formes spectaculaires et ubiquistes à l’âge du Bronze. La vue surfacique d’un bracelet du Bronze final à Arbedo-Castione (Pászthory, 1985, p. 86-87; ici : fig. 15, no 1) reprend et complique la structure losangique d’un ornement broché sur tissu en lin, sans attribution chronologique précise. Ce textile provient du site palafittique de Molino di Ledro occupé du Bronze ancien A1 à B1 et réoccupé du Bronze D au Ha A1 (Perini, 1970, p. 32; Rageth, 1974, p. 207 et suiv.). Un peigne à tisser en bois de cerf, typique de la culture des Terramares à Castione dei Marchesi, complète cette comparaison à la fin du Bronze moyen (Mutti et al., 1988; ici : fig. 15, no 3). Ces rapprochements croisés nous assurent de l’existence d’un lien structurel entre trois matériaux et objets différents. Une représentation graphique du textile se retrouve sur de la parure métallique et un accessoire de métier à tisser et ce, sur une durée minimum allant de la fin du Bronze moyen au début du Bronze final, voire sur une échelle de temps plus importante multiséculaire. Au nord de la Méditerranée, des témoignages du milieu du IIe millénaire nous renseignent sur le nec plus ultra de l’ornementation vestimentaire des thalassocraties minoennes et mycéniennes. Des fresques et des stucs ont été accidentellement piégés dans des palais détruits suite à des séismes. Hormis la présence récurrente de fins bracelets, l’ensemble fait miraculeusement étalage de l’art figuratif de l’époque avec la représentation peinte d’habits textiles brodés ou brochés (fig. 16; Barber, 1991). Le nombre important d’occurrences autorise l’application systématique de l’approche régressive des décors complexes expérimentée sur les bracelets de type Clans (fig. 16, nos 1-5, 6-9, 10-12, 13-16). Parmi les normes techniques de ces fabrications textiles, on trouve le galonnage du corsage de la Dame en rouge de Pseira (fig. 17, no 1). Il interpelle en reprenant un décor récurrent de l’âge du Bronze continental (voir fig. 9, br. 2 et 4 et fig. 24, no 5). Le renfort figuré en lisière est implanté sur les zones de tensions et de frottements. L’équivalent de cette consolidation des tissus est répertorié au Danemark sous une forme brodée sur le corsage de la Dame de Skrydstrup (fig. 17, no 2). La cape de Mold est quant à elle sans équivoque possible, la manifestation d’une ornementation couvrante de l’habillement ayant été réalisée non pas sur du textile, comme avec le corsage de Skrydstrup, mais sur du métal (fig. 17, no 3). Le renfort couvrant à fort rendement esthétique vient ici orner la tôle d’or, cette fois sans usage fonctionnel, ce qui rend l’illustration encore plus intéressante. Une norme technique fondamentale liée au textile a la faculté de migrer sur d’autres supports (voir infra). Les arbres stylistiques laissent supposer que les bracelets n’échappent pas à cette mise au diapason. Les figurations au repoussé de Mold dessinent des successions de motifs courts courbes ou en triangles surabondants dans les branches précoces du style Bignan (voir fig. 4, 6 et 9). Les bâtons en bois incisés des sites lacustres perpétuent les ornementations couvrantes durant les occupations palaffitiques du Bronze final alpin (fig. 18A, nos 1 et 2). Les exemplaires suisses de Zurich et Mörigen sont issus de contextes palafittiques attribuables à la fin de l’âge du Bronze final (nos 1 et 2). Celui de Castione (no + +3) appartient sans conteste à la phase évoluée des Terra-mares au cours du Bronze Moyen II italien (communication orale de N. Provenzano; Mutti et al., 1988). Cette culture perdure jusqu’au début de l’étape moyenne du Bronze final au cours du Bronze moyen III de la terminologie italienne, qui couvre le Bronze D-Bronze final I (Cupitó, 2012). Le décor de Castione conserve de fortes analogies avec la plupart des bracelets de la tombe de Chusclan du début du Bronze final, peut-être aux prémices du Bronze final IIa (fig. 18B, nos 8-10 ; voir supra). Les analogies sont moins franches avec d’autres bracelets italiens du début de la phase moyenne du Bronze final (fig. 18B, nos 11-12). Les trames distales à triangles hachurés sont non seulement communes aux trois bâtons, mais elles se retrouvent aussi aux extrémités de bracelets du Bronze final de la même aire géographique (fig. 18B, nos 1, 2, 5 et 7). Les occurrences vont du Bronze D2 de la jambière de la Maison Butin en l’île, à Genève (David-Elbiali, 2000, ill. 119), au Hallstatt B des bracelets massifs des lacs suisses (fig. 18B, nos 1-2). Les autres décors complexes des bâtons figurent aussi sur des bracelets du diff --git a/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_31_pg1_pg1_repeat1.md b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_31_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ea5ee8158e05b4ab1d0379e80e60e5d1a46ddc69 --- /dev/null +++ b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_31_pg1_pg1_repeat1.md @@ -0,0 +1,65 @@ +CORDIER G. (2002) – Le dépôt de l’âge du Bronze final des Châteliers à Amboise (Indre-et-Loire), Revue archéologique du Centre de la France, 41, 1, p. 5-34. + +CORDIER G. (2009) – L’âge du Bronze dans les Pays de la Loire moyenne, Joué-lès-Tours, La Simarre, 702 p. + +CORDIER G., GRUET M. (1975) – L’âge du Bronze et le premier âge du Fer en Anjou, Gallia Préhistoire, 18, p. 157-287. + +COURTOIS J.-C. (1960a) – L’âge du Bronze dans les Hautes-Alpes, Gallia Préhistoire, 3, p. 47-108. + +COURTOIS J.-C. (1960b) – Les dépôts de fondeur de Vernaison (Rhône) et de la Poype-Vaugris (Isère), Cahiers rhodaniens, 7, p. 3-25. + +CUPITÒ M. (2012) – Dinamiche costruttive e di degrado del sistema aggere-fossato della terramara di Castione dei Marchesi (Parma). Rilettura e reinterpretazione dei dati ottocenteshi, Rivista di Scienze preistoriche, 62, p. 231-248. + +DAMASIO R. A. (1997) – L’erreur de Descartes. La raison des émotions, Paris, Odile Jacob, 384 p. + +DAVID-ELBIALI M. (2000) – La Suisse occidentale au IIe millénaire av. J.-C. : chronologie, culture, intégration européenne, Lausanne, CAR (Cahiers d’archéologie romande, 80), 570 p. + +DÉCHELETTE J. (1910) – Manuel d’archéologie préhistorique, celtique et gallo-romaine , II. Archéologie celtique ou protohistorique, 1re partie. Âge du Bronze, Paris, Picard, 512 p. + +DEDET B., GIRARD A. (1992) – Une tombe du début du Bronze final II découverte en 1974 à Gaze-Menet (Chusclan, Gard), Revue archéologique de Narbonnaise, 25, 1, p. 1-18. + +DELAPORTE Y. (1991) – Les vêtements : les sociétés tradition-nelles, in J. Poirier (dir.), Histoire des mœurs, 1. Les coordonnées de l’homme et la culture matérielle, Paris, Galli-mard (Encyclopédie de la Pléiade, 47), p. 961-1031. + +DELNEF H. (2008) – Les imitations en céramique de récipients en bois aux âges du Bronze et du Fer : le cas des cistes et des pyxides = Tonimitationen von Holzgefässen in der Bronze- und Eisenzeit: das Beispiel der Zisten und Pyxiden, in F. Falkenstein, M. Schönfelder et H. Stäuble (éd.), Langfristige Erscheinungen und Brüche von der Bronze-zur Eisenzeit, actes du 5e Deutschen Archäologen-Kongress (Francfort-sur-l’Oder, 2005), Langenweißbach, Beier & Beran (Beiträge zur Ur- und Frühgeschichte Mitteleuropas, 51), p. 13-22. + +DEMAKOPOULOU K., ÉLUERE C., JENSEN J., JOCKENHÖVEL A., MOHEN J.-P. (1999) – L’Europe au temps d’Ulysse : dieux et héros de l’âge du Bronze (introduction), in L’Europe au temps d’Ulysse : dieux et héros de l’âge du Bronze, catalogue de l’exposition (Paris, Grand Palais, 30 septembre 1999-9 janvier 2000), Paris, Réunion des musées nationaux, p. 48-51. + +DORO A. (1973-1975) – Un ripostiglio di bronzi a Pinerolo : considerazioni paletnologiche, Sibrium, 12, p. 205-222. + +DOUMAS C. (1992) – The Wall-Paintings of Thera, Athènes, The Thera Foundation, Petros M. Nomikos, 191 p. + +DURAND V. (1863) – Note sur les bracelets présumés celtiques découverts à Vinols, près de Montbrison (Loire), Bulletin monumental, 29, p. 265-273. + +EAGLEMAN D. (2013) – Incognito : les vies secrètes du cerveau, Paris, Robert Laffont, 349 p. + +EBERSCHWEILER B. (1998) – Ein rätselhafter Holzstab aus dem Zürichsee, Archéologie Suisse, 21, 3, p. 98-102. + +ELUÈRE C., GOMEZ J. (1990) – Typologie des objets de l’âge du Bronze en France, VII. Bracelets, colliers, boucles, Paris, Société préhistorique française (Commission du Bronze), 163 p. + +FLEURY L. (1992) – Bracelets massifs à décor incisé du bassin de la Seine, étude typologique et technologique, mémoire de IIIe cycle, École du Louvre, Paris, 2 vol. + +FODOR J. A. (1986) – La modularité de l’esprit : essai sur la psychologie des facultés, Paris, Éditions de Minuit (Propositions), p. 178. + +FOKKENS H., ACHTERKAMP Y., KUIJPERS M. (2008) – Bracers or Bracelets? About the Functionality and Meaning of Bell Beaker Wrist-Guards, Proceedings of the Prehistoric Society, 74, p. 109-140. + +FRONTISI-DUCROUX F. (2009) – Ouvrages de dames. Ariane, Hélène, Pénélope..., Paris, Seuil, 91 p. + +FRUTIGER A. (2000) – L’Homme et ses signes, Reillanne, Atelier Perrousseaux, 319 p. + +FURMANEK V. (1973) – Bronzeindustrie der mitteldanubischen Hügelgräberkultur in Mähren, Slovenská Archeologia, 21, 1, p. 25-145. + +GABILLOT M. (2003) – Dépôts et production métallique du Bronze moyen en France nord-occidentale, Oxford, Archaeopress (BAR, International Series 1174), 471 p. + +GABILLOT M. (2005) – Des relations privilégiées entre le Nord-Ouest de la France et la région de l’Elbe au Bronze moyen, in R. Laffineur, J. Driessen et E. Warmenbol (éd.), L’âge du Bronze en Europe et en Méditerranée, actes du 14e Congrès de l’UISPP, section 11 (Liège, 2-8 septembre 2001), Oxford, Archaeopress (BAR, International Series 1337), p. 43-53. + +GALLAY A., CHAIX L. (1984) – Le site préhistorique du Petit-Chasseur (Sion-Valais), 5. Le dolmen MXI, Lausanne, Bibliothèque historique vaudoise (Cahiers d’archéologie romande, 31-32 ; Document du département d’anthropologie de l’université de Genève, 8-9), 182 p. + +GAUCHER G., ROBERT Y. (1967) – Les dépôts de bronze de Cannes-Écluse (Seine-et-Marne), Gallia Préhistoire, 10, 1, p. 169-224. + +GAUVRY Y. (2001) – La céramique chasséenne du Fort-Har-rouard à Sorel-Moussel (Eure-et-Loir), Antiquités nationales, 33, p. 37-79. + +GELL A. (1998) – Art and Agency, an Anthropological Theory, Oxford, Clarendon Press, 272 p. + +GEORGES V. (2007) – Le Forez du VIe au Ier millénaire av. J.-C. Territoires, identités et stratégies des sociétés humaines du Massif central dans le bassin amont de la Loire (France), thèse de doctorat, université de Bourgogne, Dijon, 2 vol., 435 p. + +GEORGES V. (2009) – Le Forez du VIe au Ier millénaire av. J.-C. Territoires, identités et stratégies des sociétés humaines du Massif central dans le bassin amont de la Loire (France). Thèse de doctorat soutenue le 20 décembre 2007 à l’uni- diff --git a/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_33_pg1_pg1_repeat1.md b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_33_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fb205e6da9e404e9d40c966abba702a6b43c72ff --- /dev/null +++ b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_33_pg1_pg1_repeat1.md @@ -0,0 +1,69 @@ +val et Conquereuil, Revue archéologique de l’Ouest de la France, 16, 1, p. 85-95. + +LILLIOS K. (2002) – Some New Views of the Engraved Slate Plaques of Southwest Iberia, Revista portuguesa de Arqueologia, 5, 2, p. 135-151. + +LOGIADOU-PLATONOS S. (1986) – Cnossos – La civilisation minoenne – Le palais de Minos – Exposé sommaire de la civilisation minoenne – Mythologie – Archéologie – Histoire, Fouilles, Musée, Athènes, Mathioulakis, 95 p. + +MARSILLE L. (1921) – Catalogue du Musée archéologique de la Société polymathique du Morbihan, Vannes, impr. Galles, 177 p. + +MAUGER G. (2012) – La théorie de la pratique, in F. Lebaron et G. Mauger (dir.), Bourdieu, Paris, Ellipses, p. 125-153. + +MEGAW B. R. S., HARDY E. M. (1938) – British Decorated Axes and their Diffusion during the Earlier Part of the Bronze Age, Proceedings of the Prehistoric Society (New Series), 4, 2, p. 272-307. + +MERCURIN R., CAMPOLO S. (2011) – Les dépôts d’objets en bronze dans les Alpes-Maritimes à l’âge du Bronze final : état des lieux et perspectives de recherche, in D. Garcia (dir.), L’âge du Bronze en Méditerranée : recherches récentes, Paris, Errance, p. 131-154. + +MILCENT P.-Y. (2012) – Le temps des élites en Gaule atlantique. Chronologie des mobiliers et rythmes de constitution des dépôts métalliques dans le contexte européen (XIIIe-VIIe s. av. J.-C.), Rennes, Presses universitaires de Rennes (Archéologie et Culture), 254 p. + +MILLOTTE J.-P. (1959) – Le trésor de « Carnac » et les débuts de l’âge du Fer sur le Plateau central, Revue du Gévaudan, des Causses et des Cévennes (Bulletin de la Société des lettres, sciences et arts de la Lozère), 5, p. 25-43. + +MILLOTTE J.-P. (1963) – Le Jura et les plaines de Saône aux âges des métaux, Paris, Les Belles lettres (Annales littéraires de l’université de Besançon, 59 ; Archéologie, 16), 2 vol., 455 p. + +MOHEN J.-P. (1977) – L’Âge du Bronze dans la région de Paris, catalogue synthétique des collections conservées au Musée des antiquités nationales, Saint-Germain-en-Laye, Musée des antiquités nationales et Paris, Réunion des musées nationaux, 263 p. + +P., CUNNINGTON + +R., MATTING- + +MOLENBERGH’S LEY J. B. (2012) – Brain Regions with Mirror Properties: A Meta-Analysis of 125 Human fMRI Studies, Neurosience and Behavioral Review, 36, 1, p. 341-349. + +MONTJARDIN R. (1989) – Le symbolisme solaire chasséen, Archéologie en Languedoc, 4, p. 47-51. + +MORTILLET A. DE (1885) – Hache en bronze de Sorèze, Matériaux pour l’histoire primitive et naturelle de l’homme, 19e vol., 3e série, 2, p. 193. + +MOUNTJOY P.A. (2002) – Mycenaean Pottery: An Introduction, Oxford University Press (Monograph, 36), 215 p. + +MÜLLER-KARPE H. (1959) – Beiträge zur Chronologie der Urnenfelderzeit nördlich und südlich der Alpen, Berlin, Walter de Gruyter (Römisch-Germanische Forschungen, 22), 2 vol., 334 p. + +MÜLLER-KARPE H. (1980) – Handbuch der Vorgeschichte, 4. Bronzezeit, Munich, C. H. Beck, 496 p. + +MÜLLER-KARPE H. (1985) – Frauen des 13. Jahrhunderts v. Chr., Mayence, Philip von Zabern, 201 p. + +MUTTI A., PROVENZANO N., ROSSI M. G., ROT-TOLI M. (1988) – La Terramara di Castione dei Marchesi, Bologne, Nuova Alfa (Studi e Documenti di Archeologia, 5), 456 p. + +NEUGEBAUER J.W. (1994) – Bronzezeit in Ostösterreich, St. Pölten - Vienne, Niederösterreichisches Pressehaus (Wissenschaftliche Schriftenreihe Niederösterreich, 98-101), 223 p. + +OBERKAMPF M., avec la collab. de MILLOTTE J.-P., VITAL J., LEBASCLE M.-C., PIUZ V. (1997) – Âge du Bronze de Haute-Savoie : en dehors des stations littorales, 1, Annecy, musée-château d’Annecy, 213 p. + +PASSERON J.-C (1996) – Introduction : l’espace wébérien du raisonnement comparatif, in J. Grossein, Sociologie des religions, Paris, Gallimard (Bibliothèque des sciences humaines), p. 1-49. + +PÁSZTHORY K. (1985) – Der bronzezeitliche Arm- und Beinschmuck in der Schweiz, Munich, C. H. Beck (Prähistorische Bronzefunde, 10, 3), 280 p. + +PAUTREAU J.-P. (1979) – Le Chalcolithique et l’âge du Bronze en Poitou (Vendée, Deux-Sèvres, Vienne), Poitiers, CAEP, 2 vol., 425 p. + +PERINI R. (1970) – Una decorazione su tessuto dalla palafitta di Ledro, Natura Alpina, 21, 1, p. 28-32. + +PLATON N. (1981) – La civilisation égéenne. Le Bronze récent et l’époque mycénienne, Paris, Albin Michel (L’évolution de l’humanité, 9), 478 p. + +PRESTREAU M. (2006) – Le complexe chasséen dans l’Yonne, in L. Baray (dir.), Artisanats, sociétés et civilisations : hommage à Jean-Paul Thevenot, actes du colloque (Sens, 2-3 avril 2003), Dijon, RAE (Revue archéologique de l’Est, 24), p. 87-114. + +PRIMAS M. (2008) – Bronzezeit zwischen Elbe und Po : strukturwandel in Zentraleuropa 2200-800 v. Chr., Bonn, R. Habelt (Universitätsforschungen zur prähistorischen Archäologie, 150), 267 p. + +PRIMAS M., RUOFF U. (1981) – Die Urnenfelderzeitliche Inselsiedlung „Grosser Hafner” im Zürichsee (Schweiz): Tauchausgrabung 1978-1979, Germania, 59, 1, p. 31-50. + +PRÜSSING P. (1982) – Die Messer im nördlichen West-deutschland (Schleswig-Holstein, Hamburg und Niedersachsen), Munich, C. H. Beck (Prähistorische Bronzefunde, 7, 3), 169 p. + +RAGETH J. (1974) – Der Lago di Ledro im Trentino und seine Beziehungen zu den alpinen und mitteleuropäischen Kulturen der Bronzezeit, Berichte der Römisch-Germanischen Kommission des Deutschen Archäologischen Institutes, 55, p. 73-259. + +READ C. H. (1904) – A guide to the Antiquities of the Bronze Age in the Department of British and Mediaeval Antiquities, Londres, British Museum, 160 p. + +RITTATORE-VONWILLER F. (1953-1954) – La necropoli di Canegrate, Sibrium, 1, p. 7-43. diff --git a/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_34_pg1_pg1_repeat1.md b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_34_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7dedade796ba2c1e5658c056ebbfa5fb86abbcd4 --- /dev/null +++ b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_34_pg1_pg1_repeat1.md @@ -0,0 +1,55 @@ +ROTTIER S. (2003) – Pratiques funéraires de l’étape initiale du Bronze final dans les bassins de l’Yonne et de la Haute-Seine : l’exemple des sites funéraires de Barbuise, Courtavant, La Saulsotte et Barbey aux XIVe, XIIIe et XIIe siècles avant J.-C., thèse de doctorat, université de Bourgogne, Dijon, 2 vol., 304, 473 p. + +ROTTIER S., PIETTE J., MORDANT C. (2012) – Archéologie funéraire du Bronze final dans les vallées de l’Yonne et de la haute Seine : les nécropoles de Barbey, Barbuise et La Saulsotte, Dijon, Éd. universitaires de Dijon (Art, archéologie & patrimoine), 790 p. + +ROUDIL J.-L. (1972) – L’âge du Bronze du Languedoc oriental, Paris, Klincksiek (Mémoires de la Société préhistorique française, 10), 302 p. + +ROUQUETTE D., MONTJARDIN R., CABLAT R., ROUQUETTE R., ALBAGNAC L. (1988) – Les sites chasséens de la région Thau-Gardiole (Hérault), in P. Boutié (dir.), Le Chasséen en Languedoc oriental : hommage à Jean Arnal, actes des journées d’études (Montpellier, 25-27 octobre 1985), Montpellier, université Paul Valéry (Préhistoire UPV, 1), p. 47-67. + +ROUSSOT-LARROQUE J. (1998) – Le Sud-Ouest de la France, in J. Kozłowski (dir.), Atlas du Néolithique européen, 2. L’Europe occidentale, Liège, l’université de Liège (ERAUL, 46, 2b), p. 689-761. + +ROWLANDS M. J. (1971) – A Group of Incised Decorated Arm-rings and their Signifiance for the Middle Bronze Age of Southern Britain, in G. de G. Sieveking (éd.), Prehistoric and Roman Studies Commemorating the Opening of the Department of Prehistoric and Romano-British Antiquities, Londres, The Trustees of the British Museum (British Museum Quarterly, 25, 1-4), p. 183-199. + +SARONIO P. (2000-2001) – Un ripostiglio dell’erà del Bronzo recente da Bettola, Bullettino di Paletnologia Italiana, 91-92, p. 209-221. + +SCHAEFFER [C.] F. A. (1926) – Les tertres funéraires protohistoriques dans la Forêt de Haguenau, 1. Les tumulus de l’âge du Bronze, Haguenau, impr. municipale (Publications du musée de Hagueneau), 279 p. + +SCHAUER P. (1983) – Orient im spätbronze- und früheisenzeitlichen Occident, Kultubeziehungen zwischen der Iberischen Halbinsel und dem Vorderen Orient während des späten 2. des ersen Drittes des 1. Jahrtausends v. Chr., Jachbuch des Römisch-Germanischen Zentralmuseums (Mayence), 30, p. 175-194. + +SIMON-MILLOT R. (1998) – Les bracelets en bronze du dépôt de Larnaud (Jura) conservés au Musée des antiquités nationales, Antiquités nationales, 30, p. 25-86. + +STROBEL P. (1878) – Oggetti di Legno della Mariera di Castione, Bullettino di Paletnologia italiana, 4, 2, p. 22-32. + +TAYLOR W. (1958) – Mycenean Pottery in Italy and Adjacent Areas, Cambridge, Cambridge University Press, 204 p. + +TESTART A. (2011) – Les modèles biologiques sont-ils utiles pour penser l’évolution des sociétés ?, Préhistoires méditerranéennes, 2, p. 105-122. + +THAUVIN-BOULESTIN E. (1998) – Le Bronze ancien et moyen des Grands Causses et des Causses du Quercy, Paris, CTHS (Documents préhistoriques, 11), 506 p. + +THEVENOT J.-P. (1969) – Éléments chasséens de la céramique de Chassey, Revue archéologique de l’Est de la France, 20, 1-4, p. 7-95. + +THEVENOT J.-P. (1991) – L’âge du Bronze en Bourgogne, Le dépôt de Blanot (Côte-d’Or), Dijon, RAE (Revue archéologique de l’Est, supplément 11), 158 p. + +TORBRÜGGE W. (1959) – Die Bronzezeit in der Oberpfalz, Kallmünz, M. Lassleben (Materialhefte zur bayerischen Vorgeschichte, 13), 240 p. + +VAN CUTSEM A. (2002) – Bracelets ethniques, d’Afrique, d’Asie d’Océanie et d’Amérique, Paris, Le Seuil, 378 p. + +VAQUER J. (1975) – La céramique chasséenne du Languedoc, Carcassonne, Laboratoire de Préhistoire et de palethnologie, 368 p. + +VAQUER J. (1991) – Aspect du Chasséen en Languedoc occidental, in A. Beeching, D. Binder, J.-C. Blanchet, C. Constantin, J. Dubouloz, R. Martinez, D. Mordant, J.-P. Thevenot et J. Vaquer (dir.), Identité du Chasséen, actes du colloque international (Nemours, 17-19 mai 1989), Nemours, APRAIF (Mémoires du musée de Préhistoire d’Île-de-France, 4), p. 27-37. + +VERGER S. (1992) – L’épée du guerrier et le stock de métal : de la fin du Bronze ancien à l’âge du Fer, in G. Kaenel et P. Curdy (dir.), L’Âge du Fer dans le Jura, actes du 15e Colloque de l’Association française pour l’étude de l’âge du Fer (Pontarlier, Doubs et Yverdon-les-Bains, Suisse, 9-12 mai 1991), Lausanne, Bibliothèque historique vaudoise (Cahiers d’archéologie romande, 57), p. 135-151. + +VERRON G. (1971) – Antiquités préhistoriques et protohistoriques, musée départemental des antiquités de la Seine-Maritime, Rouen, musée des antiquités de la Seine-Mari-time, 128 p. + +WATTE J.-P. (2003) – Une hache à talon à écusson richement décorée recueillie en Basse-Seine, Revue archéologique de l’Ouest, 20, p. 155-160. + +WELS-WEYRAUCH U. (1988) – Mittelbronzezeitliche Frauentrachten in Süddeutschland (Beziehungen zur Hagenauer Gruppierung), in Dynamique du Bronze moyen en Europe occidentale, actes du 113e Congrès national des sociétés savantes, commission de Pré- et Protohistoire (Strasbourg, 1988), Paris, CTHS, p. 117-134. + +WILBERTZ O. M. (1982) – Die Urnenfelderkultur in Unterfranken, Kallmünz, M. Lassleben (Materialhefte zur bayerischen Vorgeschichte, 49), 231 p. + +WYSS R. (1981) – Kostbare Perlenkette als Zeuge ältesten Fernhandels in Zürich, Helvetia archaeologica, 12, 45-46, p. 242-251. + +ZYLMANN D. (2009) – Ein reiches Frauengrab der Urnenfelderkultur aus Bad Kreuznach, Rheinland-Pfalz, Archäologisches Korrespondenblatt, 39, 4, p. 471-488. + +Vincent Georges, diff --git a/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2f733216c123ff187ffb2a234aa0d67b3204176a --- /dev/null +++ b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +L’objectif de cette contribution est d’étudier en détail cette information graphique disponible dans la littérature archéologique. Le traitement des graphismes incite à s’appuyer sur des expériences susceptibles d’être reproductibles pour en tester la réfutabilité. La démarche privilégiée consiste à enchaîner les expériences, de sorte que l’expérimentation se poursuive en tenant compte des faits précédemment établis. Cette suite d’énoncés normatifs (Habermas, 1976, p. 551) se produit au cours du critérium expérimental, selon la formule de Claude Bernard, promoteur de ce processus d’analyse dans le domaine de la biologie médicale (1865). En matière de sciences humaines, les résultats de ce parcours expérimental ont rapport avec les concepts de régularité sociologique de Max Weber ou d’invariant structural de Claude Lévi-Strauss. De ce point de vue, ils ont eux aussi vocation à peser dans les débats relatifs aux approches concurrentes des sociétés protohistoriques. Notre propos se place en amont de ces perspectives globales intrinsèquement non irréfutables et propres aux sciences humaines (Passeron, 1996, p. 44). Avant cela, la procédure inductive s’applique ici à des graphismes de bracelets sans se soucier de l’hétérogénéité des supports d’origine. Elle débute par l’obtention des vues développées de décors avant de les inclure dans une projection plane orthogonale. Cette mutation forcée entraîne un cadre comparatif homogène, préparatoire à la classification des formes obtenues dans des arbres stylistiques (AS). Ces graphes synthétiques servent alors de pierre de touche pour éclaircir l’origine et la longévité des ornementations complexes impliquées. + +## ÉTAPE N° 1 DU CRITÉRIUM EXPÉRIMENTAL LA VUE DÉVELOPPÉE DES DÉCORS + +Le déroulé à plat du décor d’un bracelet a l’avantage + +de donner une vue d’ensemble à l’intégralité des ornements de la surface externe. Cette vue dite aussi « développée » est inaugurée dès la première publication du dépôt de Vinols pour témoigner d’un art indigène présumé celtique (Durand, 1863, pl. 2). L’illustration novatrice est reproduite 47 ans plus tard, dans le célèbre Manuel d’Archéologie de J. Déchelette (1910, fig. 212). Attribuée à son auteur d’origine, elle est aussi présentée comme une source inédite pour la connaissance de l’âge du Bronze. La publicité faite à cette illustration lui a assuré sa postérité. La première publication de ce qui deviendra le dépôt éponyme du type Bignan reprend cette avantageuse présentation avant qu’elle ne s’étende aux autres bracelets richement décorés de ce type (Marsille, 1921, pl. VI ; Briard, 1965) ; la vue développée fera par ailleurs des émules dans le reste de l’Europe, faute de s’être totalement généralisée.. La morphologie du bracelet peut rendre difficile l’obtention de la vue développée. Il arrive même que sa réalisation devienne problématique en cas de fortes courbures des surfaces gravées associées à une variation importante des largeurs sur l’axe longitudinal. Un diadème du début du Bronze moyen de la nécropole autrichienne de Pit-ten illustre une telle situation ; la vue à plat, choisie dans la publication, confère une projection éclatée du décor qui ne satisfait pas à l’objectif habituellement recherché (fig. 1). Le développé uniforme attendu est contrarié par + +![](figure) + +## 10 cm + +![](figure) + +Fig. 1 – Vue développée du décor frontal du diadème en bronze de la tombe no 111 de la nécropole de Pitten, Autriche (Neugebauer, 1994, pl. 217). + +Fig. 1 – Developed view of the frontal ornament on the bronze diadem of the tomb no. 111 in Pitten necropolis, Austria (Neugebauer, 1994, pl. 217). diff --git a/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f46ace2b5a72a1d3da70c2dd4c173fff6fb29c81 --- /dev/null +++ b/outputs/multi_column/0621a0090414e4681e90a4e1ea543acca910_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,19 @@ +de notre problématique expérimentale se distingue en effet du nombre astronomique de phénotypes à l’échelle génétique et moléculaire, en sus des données anatomiques traditionnelles. Sur cette base documentaire qui + +a + +b + +c + +d + +e + +![](figure) + +Fig. 4 – Exemples de motifs différents à l’intérieur d’une vue surfacique commune. a : motifs courts courbes; b : motifs longs courbes ; c : chevrons; d : triangles et losanges hachurés; e : chevrons et triangles. + +Fig. 4 – Examples of different patterns inside a same extended view. a: short and curved patterns; b: long and curved patterns; c: herringbone patterns; d: hachured triangles and lozenge patterns; e: herringbone patterns and triangles. + +lui est propre, la phylogénétique procède actuellement à des révisions régulières qui dessinent, avec toujours plus de précision, « le cours historique de la descendance des êtres organisés à l’intérieur d’arbres phylogénétiques » (Lecointre et Le Guyader, 2009, p. 5). Il se trouve que les arbres stylistiques (AS) ont une constitution et une orientation radicalement indépendante des schémas évolutionnistes de la phylogénétique. La primauté est accordée aux associations particulières de motifs à l’échelle du bracelet, sans s’appesantir sur les motifs de bases dont nous avons vu que les distinctions formelles peuvent s’avérer trompeuses (cf. supra et fig. 4). Du fait même de leur simplicité, chacun d’eux peut avoir de surcroît plusieurs foyers d’origine étrangers à un ancêtre commun recherché en phylogénétique à par-tir des caractères synapomorphes (Lecointre et Le Guyader, 2009, p. 21). Insister sur les similarités à l’intérieur des associations de motifs revient à se placer sur le terrain de l’intentionnalité et plus généralement du contexte cognitif de leur réalisation. Les perspectives statistiques futures, pouvant encore se rattacher à la phylogénétique, seraient donc plus du domaine de la phénétique, qui met en œuvre des rapprochements sur la base de la similitude globale plutôt que de retenir des critères de différenciation comme cela se produit avec la cladistique (Lecointre et Le Guyader, 2009, p. 31-32, p. 539 et 541). La notion de racine cognitive sert ici à exprimer le dénominateur commun des occurrences à l’intérieur d’un arbre. Elle fait aussi le lien entre ceux qui conçoivent, commanditent ou portent tel ou tel décorum, sans compter les individus les plus divers qui peuvent être amenés à le côtoyer ou l’observer dans la vie sociale. Cette perspective sociale est capitale et met à mal l’application des raisonnements naturalistes matérialistes aux données d’ordre culturel (Testart, 2011). Sans pouvoir pénétrer l’âme des acteurs sociaux protohistoriques, il s’agit d’abord de s’enquérir de phénomènes physiologiques décrits dans des processus expérimentaux portant sur la perception visuelle (Frutiger, 2000, p. 35-36). Le fonctionnement inconscient sous-cortical au sommet du tronc cérébral établit un jeu complexe de rapport entre le cortex visuel et le thalamus. Il oriente à son insu l’attention d’un observateur sur les éléments non prédits (Eagle-man, 2013, chap. II, p. 66-67). Le succès des cohérences esthétiques est le fruit de ce système différentiel de perception qui les réduit pourtant à un assemblage d’effets d’optique. Ce système différentiel se construit et évolue au gré des expériences. Il instaure des hiérarchies et des complémentarités très momentanées à l’intérieur des associations entre motifs. Une fois accoutumé aux graphismes nouvellement perçus, le cerveau humain a les capacités requises pour entamer un discours réflexif relatif aux signifiés possibles des décors. Sur ce point, on peut se référer à la proposition de J. Fodor d’un fonctionnement modulaire du cortex (1986). Quant au « système limbique » de l’espace sous-cortical, il a pu être avancé qu’il contrôle aussi bien la validation des concepts que la satisfaction esthétique sous le contrôle endocrinien des hormones de récompense (Damasio, 1997, diff --git a/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6668bd54e37f0d83eff64f595dd5d300e81fbccf --- /dev/null +++ b/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,93 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Grundlagen + +Verfahren + +der + +Konstruktion + +Landtechnik + +Wirtschaft + +VEREIN DEUTSCHER INGENIEURE + +Bd. 38 (1988) Nr. 6, Seite 169 bis 200 + +Von Prof. Dr.-Ing. Dr. agr. h.c. Willi Kloth im Jahre 1951 gegründet und mit Unterstützung der Forschungsanstalt für Landwirtschaft in Braunschweig-Völkenrode herausgegeben. + +Redaktionskomitee für das Jahr 1988: Dr.-Ing. Horst Hesse, Stuttgart, Prof. Dr. Sylvester Rosegger, Völkenrode, Prof. Dr.-Ing. Franz Wieneke, Göttingen. + +Inhalt Nr. 6/88 + +Seite + +Traktorgetriebe — Entwicklungstendenzen und neuere Konzepte. Von H. Reiter u. K.T. Renius 169 + +Das Kennfeld eines Getreidesatztrockners, Teil 2: Rechenmodell für die Feuchteverteilung in der Schüttung. Von A. Coenen u. F. Wieneke 178 + +Untersuchung eines Anbaupfluges mit zentraler Arbeitsbreitenverstellung und realem Führungspunkt. Von L. Frerichs 185 + +Technisch-physikalische Grundlagen der Kornvereinzelung bei Einzelkornsämaschinen. + +Von G. Thalmann u. W. Andrä 196 + +Auszüge aus wichtigen Patent-Auslegeschriften 200 + +Herausgeber: Verein Deutscher Ingenieure, Düsseldorf + +Verlag und Vertrieb: VDI-Verlag GmbH, Düsseldorf Postfach 1139, 4000 Düsseldorf 1 + +Schriftleitung + +Dr. F. Schoedder, Institut für Biosystemtechnik, Braunschweig-Völkenrode + +Briefe und Manuskripte nur an: Schriftleitung Grundlagen der Landtechnik, Bundesallee 50, 3300 Braunschweig Telefon: 0531/596456 + +Die Schriftenreihe "Grundlagen der Landtechnik" erscheint sechsmal im Jahr. Umfang je Heft im Mittel 32 Seiten. + +Jahresbezugpreis (6 Hefte) + +In- und Ausland: DM 271,— + +VDI-Mitglieder: DM 243,90, Studenten (gegen Bescheinigung: Bestellung nur an den Verlag) DM 162,60 + +Alle Preise zuzüglich Versandspesen ab Verlagsort; + +Inland: DM 9,00 + +Ausland: DM 15,00 + +Luftpost auf Anfrage + +Einzelheftpreis: DM 47,— + +zuzüglich Versandspesen ab Verlagsort. + +Die Preise im Inland enthalten 7 % Mehrwertsteuer. + +Technische Gestaltung + +R. Bruer, Institut für Biosystemtechnik, Braunschweig-Völkenrode + +Druck: Druckerei Ruth, Braunschweig + +REINHALTUNG +DER LUFT +IM WANDEL DER ZEIT + +Von Friedrich Spiegelberg. 1983. + +X, 150 Seiten. 40 Bilder, davon 20 vierfarbig. Format 20 cm x 24 cm. Geb. mit Schutzumschlag. DM 44,— ISBN 3-18-419088-9 + +Dieses Buch soll Eindrücke davon vermitteln, wie planerische, technische und administrative Aufgaben der Luftreinhaltung im Zusammenspiel der gesellschaftlichen Kräfte gelöst wurden und werden. + +Es soll dabei die oft kontroversen Standpunkte der Beteiligten aus den Bereichen Wirtschaft, Wissenschaft und Verwaltung nicht verschweigen. + +Bei aller Gegensätzlichkeit der Einzelinteressen ist es in der Vergangenheit fast immer gelungen, einen für alle Seiten tragbaren Ausgleich zu finden, der den Notwendigkeiten des Umweltschutzes, wie ihn die Gesellschaft fordert, und den technischen und wirtschaftlichen Gegebenheiten gerecht wird. + +Ein nicht zu unterschätzender Anteil an diesen Bemühungen und den Erfolgen ist der VDI-Kommission Reinhaltung der Luft zuzuschreiben. Deshalb steht diese Kommission auch im Mittelpunkt der Betrachtungen und Erläuterungen in diesem Buch. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2df295b75c7ce257fbcf9dc256ef01b4514ad14e --- /dev/null +++ b/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Handelsdünger s. Düngung, Dünger (einschl. Verteilung) II Hausbau, landwirtschaftlicher, s. Bautechnik Heizung, Lüftung, Klimatisierung – Untersuchungen mit Wärmepumpen-Heizungsanlagen, die den Erdboden als Wärmequelle nutzen . . . . . . . . A S. 113/23 Heuwerbung, s. Ernte u. Erntemaschinen III Impulsberegnung – Die Niederschlagsintensität bei der Impulsberegnung . . . . . . . . A S. 97/100 Kenngröße – Kenngröße zum Bewerten von Bodenbearbeitungswerkzeugen und -geräten bei experimentellen Vergleichen . . . . . . . . A S. 106/13 Klimatisierung s. Heizung, Lüftung, Klimatisierung Kompartimente – Abschätzung des zeitlichen Verlaufs von Stoffgehalten in den Kompartimenten der Umwelt . . . . . . . . A S. 9/21 Körnerfrüchte I Allgemein I Allgemein – Das Kennfeld eines Getreidesatztrockners Teil 1: Praktische Versuche . . . . . . A S. 148/55 – Das Kennfeld eines Getreidesatztrockners Teil 2: Rechenmodell für die Feuchteverteilung in der Schüttung . . . . . . A S. 178/84 Konservierungstechnik s. Viehhaltung I Konstruieren – Bessere und sichere Abschätzung der Lebensdauer von Bauteilen an Schleppern und Landmaschinen . . . . . . . A S. 65/70 – Entwicklungstendenzen bei metallischen Konstruktionswerkstoffen im Maschinenbau . A S. 123/30 – Traktorgetriebe – Entwicklungstendenzen und neuere Konzepte . . . . . . . A S. 169/77 Landtechnik, allgemein – Technologieentwicklung und Technologietransfer in der Agrartechnik der Entwicklungsländer . . . . . . . A S. 155/58 Landwirtschaft, allgemein – Strukturwandlungen der Landwirtschaft und einige Auswirkungen auf Motorisierung und Mechanisierung . . . . . . . A S. 37/41 Lebensdauer – Bessere und sichere Abschätzung der Lebensdauer von Bauteilen an Schleppern und Landmaschinen . . . . . . . A S. 65/70 Linsen – Theoretische Überlegungen zu Aufbau und Funktion eines Rupforgans für die Ernte niedrig wachsender Pflanzen . . . . . . A S. 73/78 Lüftung s. Heizung, Lüftung, Klimatisierung Luftreinhaltung – Behandlung von Transport und Ausbreitung gasförmiger luftfremder Stoffe in der Umgebung von Tierhaltungen . . . . . . A S. 1/9 + +Mathematische Modelle – Abschätzung des zeitlichen Verlaufs von Stoffgehalten in den Kompartimenten der Umwelt . . . . . . . . . . . A S. 9/21 – Mathematische Modelle für den Transport von gelösten Stoffen im Boden . . . . . A S. 21/27 – Das Kennfeld eines Getreidesatztrockners Teil 2: Rechenmodell für die Feuchteverteilung in der Schüttung . . . . . A S. 178/84 Mechanisierung der Landwirtschaft – Strukturwandlungen der Landwirtschaft und einige Auswirkungen auf Motorisierung und Mechanisierung . . . . . A S. 37/41 Mikroelektronik – Prozeßführung beim Pflanzenschutz mit Hilfe der Mikroelektronik . . . . . A S. 28/35 Mineraldünger s. Düngung, Dünger (einschl. Verteilung) II Persönliches – Prof. Dr. agr. Sylvester Rosegger 75 Jahre . . R S. 36 – Prof. Moser gestorben . . . . . R S. 135 – Akademische Feier in München . . . . R S. 167 Pflanzenpflege – Die Niederschlagsintensität bei der Impulsberegnung . . . . . A S. 97/100 Pflanzenschutztechnik (einschl. Geräte) – Prozeßführung beim Pflanzenschutz mit Hilfe der Mikroelektronik . . . . . A S. 28/35 Pflüge s. Bodenbearbeitung (einschl. Geräte) Pneumatik s. Hydraulik und Pneumatik Pressen – Verdichtung und Expansion von Halmgut . . A S. 58/65 Regelung, Steuerung, Automatisierung – Prozeßführung beim Pflanzenschutz mit Hilfe der Mikroelektronik . . . . . A S. 28/35 Reifendynamik – Ackerschlepper-Reifendynamik Teil 1: Fahrbahn- und Prüfstandsergebnisse . . A S. 78/87 – Ackerschlepper-Reifendynamik Teil 2: Dynamische Federungs- und Dämpfungswerte . A S. 101/106 – Ackerschlepper-Reifendynamik Teil 3: Rolldynamik und Betriebsverhalten . . . . . A S. 137/43 Rupfen – Theoretische Überlegungen zu Aufbau und Funktion eines Rupforgans für die Ernte niedrig wachsender Pflanzen . . . . . A S. 73/78 Sägeräte u. Sämaschinen – Saatgutabgabe-Überwachungsvorrichtung für eine Sämaschine mit wenigstens einem Saatgutvorratsbehälter . . P S. 72 – Saatgutverteilvorrichtung in einer Reihen sämaschine mit gelochter Säwalze . . P S. 136 – Einzelkornsämaschine . . . . . P S. 136 – Technisch-physikalische Grundlagen der Kornvereinzelung bei Einzelkornsämaschinen A S. 196/99 – Vorrichtung zur Wahl von Körnerabständen in der Sä-Reihe . . . . . P S. 200 – Saatgutverteilvorrichtung in einer Reihen sämaschine mit gelochter Säwalze . . . . P S. 200 Samenernter s. Ernte u. Erntemaschinen Schädlingsbekämpfung s. Pflanzenschutztechnik (einschl. Geräte) + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0317e5dc8f9cf219c0fcba927229eaa35895e903 --- /dev/null +++ b/outputs/multi_column/065d792cf3923fc76a17183cfd13480cd51d_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,119 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +Schlepper (s.a. Fahrzeuge) + +– Strukturwandlungen der Landwirtschaft und einige Auswirkungen auf Motorisierung und Mechanisierung . . . . . . . . . A S. 37/41 + +– Bessere und sichere Abschätzung der Lebensdauer von Bauteilen an Schleppern und Landmaschinen . . . . . . . . . A S. 65/70 + +– Ackerschlepper-Reifendynamik Teil 1: Fahrbahn- und Prüfstandsergebnisse . . . . . . A S. 78/87 + +– Ackerschlepper-Reifendynamik Teil 2: Dynamische Federungs- und Dämpfungswerte . . . A S. 101/106 + +– Ackerschlepper-Reifendynamik Teil 3: Rolldynamik und Betriebsverhalten . . . . . . A S. 137/43 + +– Traktorgetriebe – Entwicklungstendenzen und neuere Konzepte . . . . . . . . A S. 169/77 + +Schleuderdüngerstreuer + +– Schleuderdüngerstreuer . . . . . . P S. 72 + +– Schleuderstreuer, insbesondere für gekörnte Düngemittel . . . . . . P S. 168 + +– Schleuderdüngerstreuer . . . . . . P S. 168 + +Spritzgeräte s. Pflanzenschutztechnik (einschl. Geräte) + +Stallbau s. Bautechnik + +Stalldünger s. Düngung, Dünger (einschl. Verteilung) und s. Viehhaltung + +Statistik + +– Auswirkungen einer Reduzierung der Schwankungen für Funktionen mit zwei Variablen mit Zufallscharakter . . . . . . A S. 88/93 + +– Prüfung der Zugkraftverteilung beim Pflügen auf Normalität . . . . . . . . A S. 158/67 + +Stroh- und Heupressen, Brikettierung s. Pressen + +Tagungen + +– 8. Arbeitswissenschaftliches Seminar der GAL, 26. Okt. 1988 in Hohenheim . . . . . . R S. 70 + +– 11. Internationaler CIGR-Kongreß für Agrartechnik, 4.–8. Sept. 1989 in Dublin . . . R S. 70/71 + +– ASAE-Jahrestagung 1988 . . . . . . R S. 130/31 + +– Internationale Tagung Landtechnik vom 26. bis 28. Okt. 1988 in Neu-Ulm . . . R S. 131/35 + +Technologietransfer + +– Technologieentwicklung und Technologietransfer in der Agrartechnik der Entwicklungsländer . . . . . . A S. 155/58 + +Tierhaltung s. Viehhaltung + +Trocknung, Belüftung + +I Allgemein + +II Körnerfrüchte + +III Halmgut + +I Allgemein + +II Körnerfrüchte + +– Das Kennfeld eines Getreidesatztrockners Teil 1: Praktische Versuche . . . . . A S. 148/55 + +– Das Kennfeld eines Getreidesatztrockners Teil 2: Rechenmodell für die Feuchteverteilung in der Schüttung . . . . . A S. 178/84 + +III Halmgut + +– Trocknungs- und Befeuchtungskinetik von Gras in dünnen Schichten . . . . . A S. 143/48 + +Überwachungsvorrichtung + +– Saatgutabgabe-Überwachungsvorrichtung für eine Sämaschine mit wenigstens einem Saatgutvorratsbehälter . . . . . P S. 72 + +Umwelt + +– Behandlung von Transport und Ausbreitung gasförmiger luftfremder Stoffe in der Umgebung von Tierhaltungen . . . . . A S. 1/9 + +– Abschätzung des zeitlichen Verlaufs von Stoffgehalten in den Kompartimenten der Umwelt . . . . . A S. 9/21 + +– Mathematische Modelle für den Transport von gelösten Stoffen im Boden . . . . . A S. 21/27 + +Verdichten + +– Verdichtung und Expansion von Halmgut . . A S. 58/65 + +Viehhaltung + +I Allgemein + +I Allgemein + +– Behandlung von Transport und Ausbreitung gasförmiger luftfremder Stoffe in der Umgebung von Tierhaltungen . . . . . A S. 1/9 + +– Zur Bemessung der Wärmedämmung von Ställen . . . . . A S. 49/58 + +– Beurteilung von neuen Futtergetreide-Feuchtkonservierungsverfahren mit biotechnischem Wirkprinzip . . . . . A S. 93/97 + +– Trocknungs- und Befeuchtungskinetik von Gras in dünnen Schichten . . . . . A S. 143/48 + +Wärmedämmung + +– Zur Bemessung der Wärmedämmung von Ställen . . . . . A S. 49/58 + +Wärmepumpe + +– Untersuchungen mit Wärmepumpen-Heizungsanlagen, die den Erdboden als Wärmequelle nutzen . . . . . A S. 113/23 + +Weizen (s.a. Körnerfrüchte) + +Werkstoffe + +– Entwicklungstendenzen bei metallischen Konstruktionswerkstoffen im Maschinenbau . A S. 123/30 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/068682d533c39f817bd7855be4760d9a56ef_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/068682d533c39f817bd7855be4760d9a56ef_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..165a2daf7ff238b5d7681b5f91e8ab032ea1ee37 --- /dev/null +++ b/outputs/multi_column/068682d533c39f817bd7855be4760d9a56ef_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,27 @@ +# A Combined QFT/EEAS Design Technique for Uncertain Multivariable Plants + +## Omid Namaki Shoushtari + +Control and Intelligent Processing Center of Excellence, Electrical and Computer Engineering Department, University of Tehran, Tehran, Iran. onamakis@ece.ut.ac.ir + +## Ali Khaki Sedigh + +Electrical Engineering Department, K.N. Toosi University of Technology, Tehran, Iran. + +sedigh@kntu.ac.ir + +Babak Nadjar Araabi Control and Intelligent Processing Center of Excellence, Electrical and Computer Engineering Department, University of Tehran, Tehran, Iran. araabi@ut.ac.ir + +Abstract - This paper presents a robust-adaptive control design for uncertain multivariable plants based on Quantitative Feedback Theory (QFT) and Externally Excited Adaptive Systems (EEAS). Design requirements are derived and formulated in terms of different cost functions. Also, a stochastic optimization technique is employed to optimally design the overall robust adaptive controller. This controller can handle large plant parameter uncertainties with lower control gains. Simulation results are provided to show the effectiveness and features of the proposed QFT/EEAS MIMO design methodology compared with the direct MIMO QFT design approach. + +### Index Terms – Robust Adaptive Control, QFT, EEAS, Stochastic optimization techniques. + +## I. INTRODUCTION + +Quantitative Feedback Theory (QFT) is a powerful tool in the design of robust control systems for uncertain plants. The quantitative approach provides a design methodology which enables the designer to observe clearly the limitations and trade-offs in its design [1]. QFT design methodology for uncertain multivariable plants has provided a number of competing techniques. These can be generalized into two classes, being the nonsequential design methodologies [2] and sequential design methodologies [3, 4]. In solving an m × m multivariable design problem, the synthesis problem is converted into m equivalent single-loop MISO problems, with parameter uncertainties, external disturbances and performance tolerances are derived from the original problem, and the coupling effects between MISO subsystems are treated as disturbance inputs. These coupling effects need to be rejected in the QFT design of each subsystem. These can be designed by the SISO QFT design technique [5, 6]. The disturbance-rejection requirements will normally dominate the tracking-performance requirements, in the design of each subsystem [7]. On the other hand, in the case of plants with large parameter uncertainties, QFT design technique can lead to controllers with large bandwidth. These can result in high control gains that can cause actuator saturation and reduce the control-loop performance as well as leading to over design. + +To overcome these deficiencies, QFT has been combined with other control techniques, such as the eigenstructure assignment [7] and the dynamics inversion technique [8]. Effort has also been put into designing nondiagonal controllers to reduce the gains of controllers [9-11]. Also, an adaptive QFT approach was proposed by [12] using Self Oscillating Adaptive Systems (SOAS). The resulted methodology was insensitive to large gain variations. This however causes limit cycles in the closed loop plant, which is not desirable in many practical applications. In another approach Externally Excited Adaptive Systems (EEAS) are proposed to replace SOAS [13]. This will circumvent the need for the oscillation condition and improves the quality of closed loop performance. This paper extends the robust adaptive design of controller using the QFT/EEAS approach [14] to multi-input multi-output (MIMO) systems. In all the quantitative designs, a time-consuming trial-and-error procedure is adapted and a successful compromise between various design requirements is very much dependent on the designer experience. In order to further improve the controller performance, the design steps involved are stated as design objectives and the problem is formulated as a constrained nonlinear optimization problem. The optimization problem is then solved using any of the standard random optimization techniques [15]. Genetic Algorithm is utilized here. Finally, to assess the feasibility and performance of the proposed design approach, simulation results are employed and comparison results with direct MIMO QFT are given which clearly indicate the advantages gained by the proposed design. + +## II. QUANTITATIVE FEEDBACK THEORY + +QFT is a well established methodology for the design of two-degrees of freedom (2DOF) robust control systems [1]. The QFT method takes into account quantitative information on the plant's variability (uncertainty), the robust stability requirements, tracking-performance specifications, the expected disturbance amplitude and its attenuation requirements. The main steps involved in the QFT design can be summarized as: template generation, loop shaping and pre-filter design. These steps are diff --git a/outputs/multi_column/068682d533c39f817bd7855be4760d9a56ef_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/068682d533c39f817bd7855be4760d9a56ef_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d565ee472d8e6d2a0cd4f8cb15f6adb3b940fc0e --- /dev/null +++ b/outputs/multi_column/068682d533c39f817bd7855be4760d9a56ef_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,103 @@ +## IV. DIRECT MIMO QFT DESIGN + +The MIMO QFT design technique provides a design procedure to synthesize a fixed diagonal controller transfer function matrix G(s) and prefilter F(s) to satisfy specifications on the closed-loop system shown in Fig.2, where P(s) is the MIMO uncertain plant. The basic principle for MIMO QFT design is to convert the MIMO control system into a set of equivalent MISO control systems. Using fixed-point theorem, the MIMO control problem for an m × m system can be converted into m equivalent single-loop MISO problems, each with two inputs and one output. The objective of the design is to achieve set point tracking, while minimizing the outputs due to the disturbance inputs (cross-coupling effects) [5, 6]. + +## V. COMBINED QFT/EEAS DESIGN + +## A. Problem formulation + +With no loss of generality and for simplicity, the design process is developed for 2 × 2 MIMO plants. The procedure can be easily extended to the general MIMO case. Consider the feedback structure shown in Fig. 3. The transfer function matrix \(P(s)=[p_{ij}\) (s)] , \(i,j=\) 1,2 represents the LTI uncertain 2 × 2 MIMO plant to be controlled. The \(G_{i}=\text{diag}[g_{i1}(s),g_{i2}(s)],i=\) 1,2,3 and F s = diag f11 s f represent the feedforward compensators and the prefilter matrix, respectively. Also, the nonlinear elements N1 and N2 are assumed to be ideal relays with outputs \(\pm M_{01}\) and \(\pm M_{02}\) . Moreover, V1 and V2 are the excitation signals. Let TY / R (s ) be the input-output relation from the input R(s) to the output Y (s) , which is clearly derived as + +s , which are assumed diagonal, + +( ) + +[ ( ), 22( )] + +\[T_{Y/R}(s)=[I+P(s)G(s)]^{-1}P(s)G(s)F(s)\] (8) + +( , + +) + +where, \(G=G_{3}G_{2}N_{f}G_{1}(N_{f}=\) diag n f 1 n f 2 , are the describing functions of the relays). Due to uncertainty, \(P\in\{P\}\) is a set of possible plants and it is assumed here that the plant set is finite or can be adequately approximated by a finite set so that numerical algorithms can be developed. The combined QFT/EEAS control design task is to find Gi (s) and F(s) with proper rational and stable elements, in order to satisfy the performance specifications \(\forall P\in\{P\}\). For example, tracking specifications may require that \(\forall P\in\{P\}\), + +\[B_{ij}(\omega)\leq T_{Y/R}(j\omega)_{ij}\leq A_{ij}(\omega)\] (9) + +y(t) + +r(t) + +\(P(s,\alpha)\) + +○ G(s) + +F(s) + ++ + +- + +![](figure) + +Fig. 2. 2DOF MIMO-QFT Control Structure + +\(V_{1}=A_{01}Sin(\omega_{01}t)\) + ++ + +Y(s) + +N1 + +R(s) + +F(s) + +G1(s) + +G2(s) + +← G3(s) + +P(s) + ++ + +N2 + +− + ++ + +\(V_{2}=A_{02}Sin(\omega_{02}t)\) + +![](figure) + +Fig. 3. The combined QFT/EEAS structure for 2 × 2 MIMO plants + +where, \(A_{ij}(\omega)andB_{ij}(\omega)\) are the upper and lower specifications. For simplicity, this paper will concentrate on tracking performance in (9), but there may be other specifications on sensitivity, sensor noise to input sensitivity, as well as engineering considerations such as those in direct MIMO-QFT. At high frequencies the benefits of feedback are negligible. High frequency specifications will result in large bandwidth with very little closed-loop performance improvement. It is thus recommended that the specifications to be enforced to the lowest possible frequency \(\omega_{h}\) (the Horowitz frequency). In addition, an implicit design objective is the minimization of the loop bandwidths when sensor noise attenuation is concerned. + +## B. Development of the Design Process + +In Fig.3, if the quasilinear conditions are satisfied, the closed-loop transfer of this MIMO control system could be expressed as + +\[Y(s)=T_{Y/R}R(s)=_{⎢_{⎣}t_{21}(s)t_{22}(s)_{⎦⎣}^{⎥⎢}r_{⎦^{2}}^{⎥}}^{⎡t_{11}(s)t_{12}(s)⎤⎡r_{1}⎤}\] (10) + +where, Y(s) is the system output, R(s) is the input vector. Through an appropriate transformation, the four transfer functions in the closed-loop transfer matrix are derived as: + +\[\text{For input r}_{1}:t_{11}= \frac{g_{1}q_{11}f_{11}-^{⎛}⎜_{⎜_{⎝}} \frac{t_{21}}{q_{12}} ⎞_{⎟_{⎟_{⎠}}q_{11}}}{1+g_{1}q_{11}} ,t_{21}= \frac{-⎛_{⎜_{⎜_{⎝}}} \frac{t_{11}}{q_{21}} ⎞_{⎟_{⎟_{⎠}}q_{22}}}{1+g_{2}q_{22}}\] + +\[Forinputr_{2}:t_{12}= \frac{-⎛_{⎜_{⎜_{⎝}}} \frac{t_{22}}{q_{12}} ⎞_{⎟_{⎟_{⎠}}q_{11}}}{1+g_{1}q_{11}} ,t_{21}= \frac{g_{2}q_{22}f_{22}-^{⎛}⎜_{⎜_{⎝}} \frac{t_{12}}{q_{21}} ⎞_{⎟_{⎟_{⎠}}q_{22}}}{1+g_{2}q_{22}}\] + +\[\begin{aligned} \text{where},q_{11}&=\Delta/p_{22},q_{12}=-\Delta/p_{12},q_{21}=-\Delta/p_{21,}q_{22}=\Delta/p_{11}, \\ \Delta&=p_{11}p_{22}-p_{12}p_{21}andg_{i}=g_{3i}g_{2i}n_{fi}g_{1i},i=1,2. \end{aligned}\] + +These four transfer functions represent the resulting four equivalent single-loop MISO control systems, as expressed by their signal flow graphs shown in Fig. 4. + +cij rj yij gi qii fij -1 + +1 + +![](figure) + +\[\text{Fig}.4.2\times2\text{MISO Structure fort}_{ij}(f_{ij}=0fori\neq j,c_{ij}=-\sum_{k\neq i} \frac{t_{kj}}{q_{ik}} )\] diff --git a/outputs/multi_column/069577d83be73a2373200ada5599eb824c95_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/069577d83be73a2373200ada5599eb824c95_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..38ee10a7addce4795d3071e2c3e3a20b043d1f17 --- /dev/null +++ b/outputs/multi_column/069577d83be73a2373200ada5599eb824c95_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,27 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +The Fatal Duel + +In 1804, as part of an erratic plot by Federalist extremists to cut New England and New York from the Union, Aaron Burr, their complacent tool, was nominated for Governor of New York. Alexander Hamilton denounced Burr's motives in no uncertain terms. Then Burr, giving vent to an insensate jealousy dating back to the Revolution, when his own brilliance was outdazzled by Hamilton's military, intellectual and social genius, eagerly challenged him. As TIME would have reported the Burr-Hamilton duel, had TIME been issued July 16, 1804: + +... Hamilton spent the night putting his house in order. At dawn, he, his second (Nathaniel Pendleton) and one Dr. William Hosack, were rowed from Manhattan to the Weehawken Palisades. It was hot, hazy. The river's oily swell made Mr. Pendleton sick, so Hamilton humorously held his head. Landing, they sought the well-secluded dueling ground not far above the river. + +Burr and his second (William Van Ness) were clearing the summer's underbrush. Hamilton and Burr nodded each to the other with a pleasant "Good morning." While the seconds conferred, Hamilton stood gazing across the Hudson, where his family lay still + +asleep. He was remembering his son's death on this very spot three years before at the hands of General Baker. Burr sat on a rock smoking a segar. Finally Pendleton asked: "Gentlemen, are you ready?" Burr rose. His beady eyes sparkled but his face was immobile. Pale but resolute, Hamilton took his post, his face a cameo against the green background. Pendleton handed each a loaded pistol. Again: "Gentlemen, are you ready?" "Present!" both replied. Burr fired on the instant. Hamilton rose slowly to his toes, clenched his hands, so unwittingly discharging his pistol, and fell heavily face downward. His bullet flew over Burr's head, clipped a cedar twig which fluttered to his shoulder. + +Hamilton, agonizing, was carried to his boat. He murmured: "Take good care of that pistol. It's undischarged. Pendleton knows I didn't intend to fire..." + +So, in part, TIME would have reported the fatal duel, noting also how Hamilton died the next day at the Greenwich Village home of William Bayard, how his burial in Trinity churchyard was a signal for an unprecedented outpouring of public grief. TIME too would have shown how the duel brought Burr's political ruin in the East, turned his schemes toward Louisiana and Mexico. + +Cultivated Americans, impatient with cheap sensationalism and windy bias, turn increasingly to publications edited in the historical spirit. These publications, fair-dealing, vigorously impartial, devote themselves to the public weal in the sense that they report what they see, serve no masters, fear no groups. + +TIME + +The Weekly Newsmagazine + +NEW YORK CHICAGO + +205 East 42nd Street, New York City + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_14_pg1_pg1_repeat1.md b/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_14_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f8d55e90a6eff3aebe65cfb85fb809351e9f9e90 --- /dev/null +++ b/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_14_pg1_pg1_repeat1.md @@ -0,0 +1,91 @@ +Jenum PA, Stray-Pedersen B, Melby KK, Kapperud G, Whitelaw A, Eskild A, Eng J. Incidence of Toxoplasma gondii infection in 35,940 pregnant women in Norway and pregnancy outcome for infected women. J Clin Microbiol 1998;36:2900–2906. Johnson M. Laboratory mice and rats. Mater Methods 2012;2:113. + +Junghans RP, Anderson CL. The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor. Proc Natl Acad Sci USA 1996;93:5512–5516. + +Kanamaru Y, Pfirsch S, Aloulou M, Vrtovsnik F, Essig M, Loirat C, Deschenes G, Guerin-Marchand C, Blank U, Monteiro RC. Inhibitory ITAM signaling by Fc alpha RI-FcR gamma chain controls multiple activating responses and prevents renal inflammation. J Immunol 2008;180:2669–2678. + +Kanra G, Yalcin SS, Ceyhan M, Yurdakok K. Clinical trial to evaluate immunogenicity and safety of inactivated hepatitis A vaccination starting at 2-month-old children. Turk J Pediatr 2000;42:105–108. + +Kanswal S, Katsenelson N, Selvapandiyan A, Bram RJ, Akkoyunlu M. Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL. J Immunol 2008;181:976–990. + +Kaur K, Chowdhury S, Greenspan NS, Schreiber JR. Decreased expression of tumor necrosis factor family receptors involved in humoral immune responses in preterm neonates. Blood 2007;110:2948–2954. + +Kim D, Huey D, Oglesbee M, Niewiesk S. Insights into the regulatory mechanism controlling the inhibition of vaccine-induced seroconversion by maternal antibodies. Blood 2011;117:6143–6151. + +Kincade PW, Medina KL, Payne KJ, Rossi MI, Tudor KS, Yamashita Y, Kouro T. Early B-lymphocyte precursors and their regulation by sex steroids. Immunol Rev 2000; 175:128–137. + +Koelsch K, Zheng NY, Zhang Q, Duty A, Helms C, Mathias MD, Jared M, Smith K, Capra JD, Wilson PC. Mature B cells class switched to IgD are autoreactive in healthy individuals. J Clin Invest 2007;117:1558–1565. + +Kohl S, Loo LS. The relative role of transplacental and milk immune transfer in protection against lethal neonatal herpes simplex virus infection in mice. J Infect Dis 1984;149:38–42. + +Kovarik J, Martinez X, Pihlgren M, Bozzotti P, Tao MH, Kipps TJ, Wild TF, Lambert PH, Siegrist CA. Limitations of in vivo IL-12 supplementation strategies to induce Th1 early life responses to model viral and bacterial vaccine antigens. Virology 2000; 268:122–131. + +Kovarik J, Gaillard M, Martinez X, Bozzotti P, Lambert PH, Wild TF, Siegrist CA. Induction of adult-like antibody, Th1, and CTL responses to measles hemagglutinin by early life murine immunization with an attenuated vaccinia-derived NYVAC(K1L) viral vector. Virology 2001;285:12–20. + +Kwak JY, Beaman KD, Gilman-Sachs A, Ruiz JE, Schewitz D, Beer AE. Up-regulated expression of CD56+, CD56+/CD16+, and CD19+ cells in peripheral blood lymphocytes in pregnant women with recurrent pregnancy losses. Am J Reprod Immunol 1995;34:93–99. + +Lagergard T, Shiloach J, Robbins JB, Schneerson R. Synthesis and immunological properties of conjugates composed of group B streptococcus type III capsular polysaccharide covalently bound to tetanus toxoid. Infect Immun 1990;58:687–694. + +Legge A, Dodds L, MacDonald NE, Scott J, McNeil S. Rates and determinants of seasonal influenza vaccination in pregnancy and association with neonatal outcomes. CMAJ 2014;186:E157–E164. + +Levan-Petit I, Lelievre E, Barra A, Limosin A, Gombert B, Preud’homme JL, Lecron JC. T(h)2 cytokine dependence of IgD production by normal human B cells. Int Immunol 1999;11:1819–1828. + +Leviton MP, Lacayo JC, Choi KY, Hernandez-Alvarado N, Wey A, Schleiss MR. An attenuated cytomegalovirus vaccine with a deletion of a viral chemokine gene is protective against congenital CMV transmission in a guinea pig model. Clin Dev Immunol 2013;2013:906948. + +Levy O. Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat Rev Immunol 2007;7:379–390. + +Li N, Zhao M, Hilario-Vargas J, Prisayanh P, Warren S, Diaz LA, Roopenian DC, Liu Z. Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases. J Clin Invest 2005;115:3440–3450. + +Li S, Rouphael N, Duraisingham S, Romero-Steiner S, Presnell S, Davis C, Schmidt DS, Johnson SE, Milton A, Rajam G et al. Molecular signatures of antibody responses derived from a systems biology study of five human vaccines. Nat Immunol 2014; 15:195–204. + +Lim ML, Chong CY, Tee WS, Lim WY, Chee JJ. Influenza A/H1N1 (2009) infection in pregnancy--an Asian perspective. BJOG 2010;117:551–556. + +Lindsay L, Jackson LA, Savitz DA, Weber DJ, Koch GG, Kong L, Guess HA. Community influenza activity and risk of acute influenza-like illness episodes among healthy unvaccinated pregnant and postpartum women. Am J Epidemiol 2006;163:838–848. + +Litwin SD, Zehr BD, Insel RA. Selective concentration of IgD class-specific antibodies in human milk. Clin Exp Immunol 1990;80:263–267. + +Liu J, Li Q, Cui H, Liu C. Severe and critical cases of H1N1 influenza in pregnancy: a Chinese perspective. J Postgrad Med 2011;57:298–301. + +Lotz M, Gutle D, Walther S, Menard S, Bogdan C, Hornef MW. Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells. J Exp Med 2006;203:973–984. + +Louik C, Ahrens K, Kerr S, Pyo J, Chambers C, Jones KL, Schatz M, Mitchell AA. Risks and safety of pandemic H1N1 influenza vaccine in pregnancy: exposure prevalence, preterm delivery, and specific birth defects. Vaccine 2013;31:5033–5040. + +Mackenzie JS, Williams K, Papadimitriou J. Influenza A virus and its influence on the outcome of pregnancy in the mouse. Dev Biol Stand 1977;39:489–496. + +Mackenzie IS, MacDonald TM, Shakir S, Dryburgh M, Mantay BJ, McDonnell P, Layton D. Influenza H1N1 (swine flu) vaccination: a safety surveillance feasibility study using self-reporting of serious adverse events and pregnancy outcomes. Br J Clin Pharmacol 2012;73:801–811. + +MacLennan IC, Bazin H, Chassoux D, Gray D, Lortan J. Comparative analysis of the development of B cells in marginal zones and follicles. Adv Exp Med Biol 1985; 186:139–144. + +Madoff LC, Michel JL, Gong EW, Rodewald AK, Kasper DL. Protection of neonatal mice from group B streptococcal infection by maternal immunization with beta C protein. Infect Immun 1992;60:4989–4994. + +Madoff LC, Paoletti LC, Tai JY, Kasper DL. Maternal immunization of mice with group B streptococcal type III polysaccharide-beta C protein conjugate elicits protective antibody to multiple serotypes. J Clin Invest 1994;94:286–292. + +Mahmoud F, Abul H, Omu A, Al-Rayes S, Haines D, Whaley K. Pregnancy-associated changes in peripheral blood lymphocyte subpopulations in normal Kuwaiti women. Gynecol Obstet Invest 2001a;52:232–236. + +Mahmoud F, Diejomaoh M, Omu AE, Abul H, Haines D. Lymphocyte subpopulation frequency and presence of anti-cardiolipin and anti-nuclear antibodies in peripheral blood of Kuwaiti women experiencing recurrent pregnancy loss. J Obstet Gynaecol 2001b;21:587–590. + +Malanchere E, Huetz F, Coutinho A. Maternal IgG stimulates B lineage cell development in the progeny. Eur J Immunol 1997;27:788–793. + +Mantis NJ, Cheung MC, Chintalacharuvu KR, Rey J, Corthesy B, Neutra MR. Selective adherence of IgA to murine Peyer’s patch M cells: evidence for a novel IgA receptor. J Immunol 2002;169:1844–1851. + +Martinez X, Brandt C, Saddallah F, Tougne C, Barrios C, Wild F, Dougan G, Lambert PH, Siegrist CA. DNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life. Proc Natl Acad Sci USA 1997;94:8726–8731. + +Martinez X, Li X, Kovarik J, Klein M, Lambert PH, Siegrist CA. Combining DNA and protein vaccines for early life immunization against respiratory syncytial virus in mice. Eur J Immunol 1999;29:3390–3400. + +Medina KL, Kincade PW. Pregnancy-related steroids are potential negative regulators of B lymphopoiesis. Proc Natl Acad Sci USA 1994;91:5382–5386. + +Medina KL, Smithson G, Kincade PW. Suppression of B lymphopoiesis during normal pregnancy. J Exp Med 1993;178:1507–1515. + +Medina KL, Strasser A, Kincade PW. Estrogen influences the differentiation, proliferation, and survival of early B-lineage precursors. Blood 2000;95: 2059–2067. + +Medina KL, Garrett KP, Thompson LF, Rossi MI, Payne KJ, Kincade PW. Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen. Nat Immunol 2001;2:718–724. + +Mestas J, Hughes CC. Of mice and not men: differences between mouse and human immunology. J Immunol 2004;172:2731–2738. + +Michaelsson J, Mold JE, McCune JM, Nixon DF. Regulation of T cell responses in the developing human fetus. J Immunol 2006;176:5741–5748. + +Mickleson KN, Moriarty KM. Immunoglobulin levels in human colostrum and milk. J Pediatr Gastroenterol Nutr 1982;1:381–384. + +Moffatt K, McNally C. Vaccine refusal: perspectives from pediatrics. In: Chatterjee A (ed). Vaccinophobia and Vaccine Controversies of the 21st Century. New York: Springer Science+Business Media, 2013, 97–118. + +Moffett A, Loke C. Immunology of placentation in eutherian mammals. Nat Rev Immunol 2006;6:584–594. diff --git a/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_16_pg1_pg1_repeat1.md b/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_16_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..89dbde88c6339600f6325a4c07275f7849816612 --- /dev/null +++ b/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_16_pg1_pg1_repeat1.md @@ -0,0 +1,93 @@ +Sappenfield E, Jamieson DJ, Kourtis AP. Pregnancy and susceptibility to infectious diseases. Infect Dis Obstet Gynecol 2013;2013:752852. + +Sarvas H, Kurikka S, Seppala IJ, Makela PH, Makela O. Maternal antibodies partly inhibit an active antibody response to routine tetanus toxoid immunization in infants. J Infect Dis 1992;165:977–979. + +Sarzotti M, Robbins DS, Hoffman PM. Induction of protective CTL responses in newborn mice by a murine retrovirus. Science 1996;271:1726–1728. + +Schanzer DL, Langley JM, Tam TW. Influenza-attributed hospitalization rates among pregnant women in Canada 1994–2000. J Obstet Gynaecol Can 2007;29:622–629. + +Schleiss MR, Lacayo JC, Belkaid Y, McGregor A, Stroup G, Rayner J, Alterson K, Chulay JD, Smith JF. Preconceptual administration of an alphavirus replicon UL83 (pp65 homolog) vaccine induces humoral and cellular immunity and improves pregnancy outcome in the guinea pig model of congenital cytomegalovirus infection. J Infect Dis 2007;195:789–798. + +Schleiss MR, Buus R, Choi KY, McGregor A. An attenuated CMV vaccine with a deletion in tegument protein GP83 (pp65 Homolog) protects against placental infection and improves pregnancy outcome in a guinea pig challenge model. Future Virol 2013; 8:1151–1160. + +Schleiss MR, Choi KY, Anderson J, Mash JG, Wettendorff M, Mossman S, Van Damme M. Glycoprotein B (gB) vaccines adjuvanted with AS01 or AS02 protect female guinea pigs against cytomegalovirus (CMV) viremia and offspring mortality in a CMV-challenge model. Vaccine 2014;32:2756–62. + +Schwab I, Nimmerjahn F. Intravenous immunoglobulin therapy: how does IgG modulate the immune system? Nat Rev Immunol 2013;13:176–189. + +Sette A, Rappuoli R. Reverse vaccinology: developing vaccines in the era of genomics. Immunity 2010;33:530–541. + +Sewell HF, Matthews JB, Flack V, Jefferis R. Human immunoglobulin D in colostrum, saliva and amniotic fluid. Clin Exp Immunol 1979;36:183–188. + +Shakib JH, Korgenski K, Sheng X, Varner MW, Pavia AT, Byington CL. Tetanus, diphtheria, acellular pertussis vaccine during pregnancy: pregnancy and infant health outcomes. J Pediatr 2013;163:1422–1426 e1421–1424. + +Sheffield JS, Greer LG, Rogers VL, Roberts SW, Lytle H, McIntire DD, Wendel GD Jr. Effect of influenza vaccination in the first trimester of pregnancy. Obstet Gynecol 2012; 120:532–537. + +Siegrist CA. Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants. Vaccine 2003;21:3406–3412. + +Siegrist CA, Aspinall R. B-cell responses to vaccination at the extremes of age. Nat Rev Immunol 2009;9:185–194. + +Siegrist CA, Barrios C, Martinez X, Brandt C, Berney M, Cordova M, Kovarik J, Lambert PH. Influence of maternal antibodies on vaccine responses: inhibition of antibody but not T cell responses allows successful early prime-boost strategies in mice. Eur J Immunol 1998a;28:4138–4148. + +Siegrist CA, Cordova M, Brandt C, Barrios C, Berney M, Tougne C, Kovarik J, Lambert PH. Determinants of infant responses to vaccines in presence of maternal antibodies. Vaccine 1998b;16:1409–1414. + +Siem RA, Ly H, Imagawa DT, Adams JM. Influenza virus infections in pregnant mice. J Neuropathol Exp Neurol 1960;19:125–129. + +Silverstein AM. Ontogeny of the immune response. Science 1964;144:1423–1428. + +Siston AM, Rasmussen SA, Honein MA, Fry AM, Seib K, Callaghan WM, Louie J, Doyle TJ, Crockett M, Lynfield R et al. Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States. JAMA 2010;303:1517–1525. + +Smithson G, Couse JF, Lubahn DB, Korach KS, Kincade PW. The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis. J Immunol 1998;161:27–34. + +Soydinc HE, Celen MK, Yildiz B, Sak ME, Evsen MS, Gul T. Pregnancy and H1N1 infection in Southeast Turkey. J Infect Dev Ctries 2012;6:644–649. + +Stapleton NM, Andersen JT, Stemerding AM, Bjarnarson SP, Verheul RC, Gerritsen J, Zhao Y, Kleijer M, Sandlie I, de Haas M et al. Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential. Nat Commun 2011;2:599. + +Steele MG, Leslie GA. Immunoglobulin D in rat serum, saliva and milk. Immunology 1985;55:571–577. + +Steinhoff MC, Omer SB, Roy E, El Arifeen S, Raqib R, Dodd C, Breiman RF, Zaman K. Neonatal outcomes after influenza immunization during pregnancy: a randomized controlled trial. CMAJ 2012;184:645–653. + +Stoll BJ, Hansen N. Infections in VLBW infants: studies from the NICHD Neonatal Research Network. Semin Perinatol 2003;27:293–301. + +Stoll BJ, Hansen N, Fanaroff AA, Wright LL, Carlo WA, Ehrenkranz RA, Lemons JA, Donovan EF, Stark AR, Tyson JE et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 2002;110:285–291. + +Tamiolakis D, Anastasiadis P, Hatzimichael A, Liberis B, Karamanidis D, Kotini A, Petrakis G, Romanidis K, Papadopoulos N. Spontaneous abortions with increased CD5 positive cells in the placental tissue during the first trimester of gestation. Clin Exp Obstet Gynecol 2001;28:261–265. + +Telemo E, Hanson LA. Antibodies in milk. J Mammary Gland Biol Neoplasia 1996; 1:243–249. + +Timens W, Boes A, Rozeboom-Uiterwijk T, Poppema S. Immaturity of the human splenic marginal zone in infancy. Possible contribution to the deficient infant immune response. J Immunol 1989;143:3200–3206. + +Tizzard I. Immunity in the fetus and newborn. In: Tizzard I (ed). Veterinary Immunology. Philadelphia: WB Saunders, 1987, 171–184. + +Trautmann L, Sekaly RP. Solving vaccine mysteries: a systems biology perspective. Nat Immunol 2011;12:729–731. + +Troisi CL, Hollinger FB, Krause DS, Pickering LK. Immunization of seronegative infants with hepatitis A vaccine (HAVRIX; SKB): a comparative study of two dosing schedules. Vaccine 1997;15:1613–1617. + +Valdimarsson H, Mulholland C, Fridriksdottir V, Coleman DV. A longitudinal study of leucocyte blood counts and lymphocyte responses in pregnancy: a marked early increase of monocyte-lymphocyte ratio. Clin Exp Immunol 1983;53:437–443. + +van den Berg JP, Westerbeek EA, Berbers GA, van Gageldonk PG, van der Klis FR, van Elburg RM. Transplacental transport of IgG antibodies specific for pertussis, diphtheria, tetanus, Haemophilus influenzae type b, and Neisseria meningitidis serogroup C is lower in preterm compared with term infants. Pediatr Infect Dis J 2010;29:801–805. + +Verthelyi DI, Ahmed SA. Estrogen increases the number of plasma cells and enhances their autoantibody production in nonautoimmune C57BL/6 mice. Cell Immunol 1998;189:125–134. + +Victor JR, Muniz BP, Fusaro AE, de Brito CA, Taniguchi EF, Duarte AJ, Sato MN. Maternal immunization with ovalbumin prevents neonatal allergy development and up-regulates inhibitory receptor Fc gamma RIIB expression on B cells. BMC Immunol 2010;11:11. + +Vieira P, Rajewsky K. The half-lives of serum immunoglobulins in adult mice. Eur J Immunol 1988;18:313–316. + +Vitoratos N, Papadias C, Economou E, Makrakis E, Panoulis C, Creatsas G. Elevated circulating IL-1beta and TNF-alpha, and unaltered IL-6 in first-trimester pregnancies complicated by threatened abortion with an adverse outcome. Mediators Inflamm 2006;2006:30485. + +Wang G, Miyahara Y, Guo Z, Khattar M, Stepkowski SM, Chen W. ‘Default’ generation of neonatal regulatory T cells. J Immunol 2010;185:71–78. + +Wang Z-Y, Mathiarasu A, Hong P, Xu Y, Li A, Bluth M, Lum L, Huang B, Romero R, Cerutti A et al. Defective induction of regulatory B cells by decidua stromal cells underlies the pathogenesis of preterm birth. J Immunol 2013;190:171.119. + +Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, Nussenzweig MC. Predominant autoantibody production by early human B cell precursors. Science 2003;301:1374–1377. + +Warfel JM, Papin JF, Wolf RF, Zimmerman LI, Merkel TJ. Maternal and neonatal vaccination protects newborn baboons from pertussis infection. J Infect Dis 2014. doi:10.1093/infdis/jiu090. + +Watanabe M, Iwatani Y, Kaneda T, Hidaka Y, Mitsuda N, Morimoto Y, Amino N. Changes in T, B, and NK lymphocyte subsets during and after normal pregnancy. Am J Reprod Immunol 1997;37:368–377. + +Wessels MR, Paoletti LC, Kasper DL, DiFabio JL, Michon F, Holme K, Jennings HJ. Immunogenicity in animals of a polysaccharide-protein conjugate vaccine against type III group B Streptococcus. J Clin Invest 1990;86:1428–1433. + +Wessels MR, Paoletti LC, Rodewald AK, Michon F, DiFabio J, Jennings HJ, Kasper DL. Stimulation of protective antibodies against type Ia and Ib group B streptococci by a type Ia polysaccharide-tetanus toxoid conjugate vaccine. Infect Immun 1993; 61:4760–4766. + +Wesumperuma HL, Perera AJ, Pharoah PO, Hart CA. The influence of prematurity and low birthweight on transplacental antibody transfer in Sri Lanka. Ann Trop Med Parasitol 1999;93:169–177. + +Wiersma EJ, Coulie PG, Heyman B. Dual immunoregulatory effects of monoclonal IgG-antibodies: suppression and enhancement of the antibody response. Scand J Immunol 1989;29:439–448. diff --git a/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5a44b0079bdf52644f881d83dd5291806025a735 --- /dev/null +++ b/outputs/multi_column/06ba2a90e81d76b586e6b884bf67133012a9_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,48 @@ +et al., 1994; Englund et al., 1995; Troisi et al., 1997; Dagan et al., 2000; Kanra et al., 2000; Crowe et al., 2001; Getahun and Heyman, 2009), although cell-mediated immune responses are not affected (Martinez et al., 1997, 1999; Siegrist et al., 1998a, b). The inhibitory effect on infant response to vaccination has been, however, highly variable among different vaccines and even different studies of the same vaccine (Siegrist, 2003). Many mechanisms of how maternal antibodies may inhibit infant humoral immune response to vaccines (Table II) can be postulated, some of which are based on the understanding of the immunosuppressive mechanism of passive intravenous immunoglobulins (IVIGs) (Schwab and Nimmerjahn, 2013). However, studies on how maternal antibodies may actually interfere with vaccine-induced humoral immunity in infants are needed, as maternal antibodies differ from IVIGs in quantity, structure, composition and function, such as half-life, glycosylation pattern, isotype and affinity for antigens and Fc receptors, and may interfere with the infant immune response via distinct mechanisms from those used by IVIGs. For example, the significant increase in the production of maternal asymmetric IgG with an extra carbohydrate moiety in one of the F(ab’) domains during pregnancy (Gutierrez et al., 2005) may allow such IgG molecules to uniquely function as univalent blocking antibodies against vaccine antigens differently from IVIGs in infants (Pasetti et al., 1997). Since maternal antibodies decline in the infant, interference of the infant humoral immunity to vaccination was found to mainly impact primary immunization in early infancy but not subsequent boosting (Glezen, 2003). However, this should not be a reason to dismiss maternal immunization, as a reduced antibody titer after infant vaccination may be acceptable if the high morbidity and mortality can be mitigated in the first months of life by maternal vaccination. Indeed, studies in mice show that maternal antibodies can promote immune maturation in the offspring (Malanchere et al., 1997; Fink et al., 2008). The pros and cons of maternal vaccination on the immune responses to any given infant vaccination protocol should therefore be evaluated individually. + +# Humoral immune modulations in pregnancy that influence vaccine efficacy and safety + +All of the current maternal vaccination formulations are initially designed for and tested in the non-pregnant population. However, substantial immune modulations take place both systemically and in the reproductive mucosa during different stages of pregnancy, highlighting the distinct possibility of sub-optimal or qualitatively different vaccine responses in pregnant women. Research is thus needed to elucidate pregnancy-associated immune alterations in both normal and complicated pregnancies that can influence vaccine responses. The various pregnancy-associated changes in the T, natural killer, myeloid, cytokine and chemokine compartments have been discussed in several excellent reviews (Moffett and Loke, 2006; Mor and Cardenas, 2010, Chen et al., 2012; Pazos et al., 2012a; Erlebacher, 2013). As B cells are the final effectors of humoral immunity, we focus on the modulations in the B cell compartment and their potential influence on vaccine-induced antibody response. The central and peripheral B cell compartments undergo quantitative changes during pregnancy, with a contraction of peripheral B cell numbers (Fig. 2). Initial studies in mice showed a profound reduction of B cell precursors in the bone marrow from early pregnancy, which was likely mediated by estrogen (Medina et al., 1993, 2000). Consistently, the overall antibody titers to influenza infection are lower in pregnant mice (Medina and Kincade, 1994; Smithson et al., 1998; Chan et al., 2010). Similar changes have also been found in humans by many studies (Christiansen et al., 1976; Moore et al., 1983; Valdimarsson et al., 1983; Iwatani et al., 1988; Watanabe et al., 1997; Mahmoud et al., 2001a). Of note, steroid hormones regulate humoral immunity at multiple stages of B cell development. For example, the very early precursors of pro-B cells are particularly sensitive to negative regulation by + +Table II Postulated mechanisms of maternal antibody-mediated inhibition of infant humoral immune response to vaccination. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
MechanismSupporting references
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F(ab’)2-dependentClearance of vaccine antigens by maternal IgG via opsonization and subsequent FcgR-mediated phagocytosisGetahun and Heyman (2009)
Neutralization of live viral vaccine epitopes by maternal IgG Inhibition of infant B cell recognition of vaccine epitopes by maternal IgG via antigenic maskingAlbrecht et al. (1977) and Naniche (2009) Wiersma et al. (1989), Jelonek et al. (1996), Nohynek et al. (1999) and Getahun and Heyman (2009)
Fc-dependentClearance of vaccine antigens by maternal IgG via FcgR-mediated phagocytosis after antigen opsonizationGetahun and Heyman (2009)
Inhibition of infant B cell activation, survival and antibody production by maternal IgG via the inhibitory receptor FcgRIIBVictor et al. (2010) and Kim et al. (2011)
Inhibition of infant antigen-presenting cells by maternal IgG via the inhibitory receptor Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Non-integrin (DC-SIGN), also called CD209 Saturation of infant endothelial or myeloid FcRn by maternal IgG and acceleration of catabolism of vaccine-induced infant IgGAnthony et al. (2008) Vieira and Rajewsky (1988), Junghans and Anderson (1996), Hansen and Balthasar (2002) and Li et al. (2005)
Inhibition of infant dendritic cells (DCs) by ingested and absorbed maternal IgA via FcaRIPasquier et al. (2005) and Kanamaru et al. (2008)
Inhibition of infant B cells and follicular DCs and macrophages by ingested and absorbed maternal IgA via Fca/mRHonda et al. (2009)
diff --git a/outputs/multi_column/06c4bdabd51644320829c59e425e2350493b_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/06c4bdabd51644320829c59e425e2350493b_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..30f8f87d8529b11a6a2edf5371871b3385c22592 --- /dev/null +++ b/outputs/multi_column/06c4bdabd51644320829c59e425e2350493b_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,5 @@ +mengalami percepatan bone loss. Studi yang dilakukan pada 200.000 wanita berusia ≥50 tahun dengan mengukur nilai BMD dan dibandingkan dengan standar WHO menunjukkan bahwa 40% menderita osteopenia (1-2,5 SD di bawah nilai normal) dan sebanyak 7% menderita osteoporosis.15 Usia akan mempengaruhi kepadatan tulang seseorang. Peningkatan bone loss terjadi seiring dengan pertambahan usia, terutama pada lansia. Kehilangan massa tulang yang terjadi pada wanita pascamenopause sebesar 0,5-1% per tahun dari berat tulang.3 Semakin tua usia seseorang, terutama pada masa pascamenopause, kehilangan massa tulang progresif terjadi sebagai akibat penggantian atau pengisian tulang yang tidak lengkap setelah diresorpsi.24 World Health Organization mengelompokkan usia 46-59 tahun ke dalam kategori middle age (usia pertengahan) dan ≥60 tahun termasuk kategori elderly (lansia).22 Hasil penelitian ini menunjukkan bahwa subjek yang berusia ≥60 tahun lebih banyak ditemukan pada kelompok kasus daripada kelompok kontrol. Secara teori, wanita pascamenopause akan memasuki range risiko fraktur setelah usia 60 tahun karena pada usia di atas 60 tahun terjadi abnormalitas bone turnover (proses penyerapan tulang lebih banyak terjadi daripada pembentukan tulang) sehingga risiko osteoporosis dan fraktur meningkat.15 Wanita pascamenopause juga akan mengalami penurunan tinggi badan hingga 20 cm antara usia 50-80 tahun, menimbulkan gambaran khas dowager hump (wanita tua yang bungkuk).8 Pada tabel 2 dapat dilihat bahwa sebanyak 40% subjek pada kelompok kasus mengalami menopause selama >10 tahun. Hal ini menunjukkan bahwa semakin lama seseorang mengalami menopause maka kepadatan tulang cenderung rendah. Hal ini berkaitan dengan berkurangnya hormon estrogen pada masa menopause. Defisiensi hormon estrogen pada masa menopause mengakibatkan terjadinya resorpsi tulang yang berlebihan dan menghambat proses pengisian pada rongga resorpsi sehingga tulang trabekular mengalami penipisan. Hal ini menjadikan struktur tulang trabekular lemah sehingga lebih mudah fraktur.24 Olahraga secara teratur, terutama olahraga pembebanan (weight-bearing) seperti berjalan, berlari, senam, dan menari dapat meningkatkan massa tulang dengan meningkatkan massa otot yang memberikan pembebanan pada tulang sehingga kepadatan tulang meningkat. Hasil penelitian pada tabel 2 menunjukkan bahwa sebagian besar subjek memiliki kebiasaan olahraga yang kurang pada kelompok kasus dan kontrol. Kebiasaan olahraga yang kurang dapat meningkatkan risiko osteoporosis. Hal ini seperti penelitian yang dilakukan pada wanita lansia di Bogor menunjukkan bahwa sebagian besar subjek jarang melakukan kegiatan olahraga sehingga aktivitas fisiknya tergolong ringan atau kurang, dan berisiko mengalami osteoporosis 8 kali lebih besar.25 Studi kohort pada lebih dari 61.000 wanita pascamenopause menunjukkan bahwa mereka yang berjalan sedikitnya empat jam setiap minggu mempunyai 41% risiko fraktur yang lebih rendah daripada mereka yang berjalan kurang dari satu jam setiap minggu.17 Olahraga memberikan beban mekanis pada tulang. Adanya pembebanan mekanik pada tulang (skeletal load) menimbulkan stress mekanik dan strain (resultant tissue deformation). Hal ini mengakibatkan terjadinya pembentukan tulang pada permukaan periostal dan berkurangnya penyerapan tulang sehingga memperkuat tulang.26 Olahraga (tegangan) dapat meningkatkan jumlah sel osteoblas dan menurunkan jumlah sel osteoklas melalui mekanisme mekanotransduksi. Tegangan yang dihasilkan olahraga akan menginduksi produksi nitrit oksida (NO), yang menekan aktivitas osteoklas dan meningkatkan aktivitas osteoblas. Tegangan ini juga menginduksi sintesis prostaglandin dengan cara meningkatkan aktivitas siklooksigenase. Prostaglandin kemudian akan menstimulasi aktivitas osteoblas melalui insulin growth factor, yang meningkat pada awal stimulasi mekanis (olahraga). Olahraga yang paling sederhana adalah berjalan kaki selama 30-60 menit sehari.27 Gangguan remodeling tulang pada masa menopause menyebabkan bone turnover yang cepat dan mempercepat hilangnya mineral-mineral tulang. Olahraga pembebanan perlu dilakukan untuk memberikan stress mekanik pada tulang rangka, latihan ini efektif untuk mencegah kehilangan massa tulang karena penuaan. Olahraga pembebanan seperti berjalan, jogging, bermain tenis atau menaiki tangga akan menghasilkan strain mekanik yang cukup bagi wanita pascamenopause sehat.28 + +## Faktor-faktor yang Berhubungan dengan Kepadatan Tulang Rendah pada Wanita Pascamenopause + +Hasil penelitian pada tabel 1 menunjukkan bahwa rerata asupan protein total, protein hewani dan protein nabati pada kelompok kontrol lebih tinggi daripada kelompok kasus. Hasil yang sama ditunjukkan pada penelitian case control di Spanyol pada subjek berusia ≥65 tahun, yaitu diff --git a/outputs/multi_column/06dda119744c1212fbb39a789dc34f023f6c_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/06dda119744c1212fbb39a789dc34f023f6c_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3ae622a2047d5fe72e9d45b06dd9cf12192b7fdc --- /dev/null +++ b/outputs/multi_column/06dda119744c1212fbb39a789dc34f023f6c_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,35 @@ +reach each one some muscle strength is applied. Another difference is the use of amplitude envelope instead of some other feature combination in time or frequency domain. This may be the reasons to the smaller classification accuracies for a number of classes greater than 5 compared to the results obtained from other authors, which continue with classification rates above 90 for these class configurations (Hargrove, Englehart and Hudgins, 2007; Ahsan, Ibrahimy and Khalifa, 2010; Basu, Bhattacharyya and Kim, 2010; Scheme and Englehart, 2011). However, considering the type of movement and distinctive classes, the low level of contraction and the use of the amplitude envelope, which require a minimum processing effort, for a small number of classes, the systems had performed well. On the other hand, the process based on RLDA was very fast, while the process based on MLP was time consuming as much to define adequate parameters as for as network training. There was no pattern for the number of hidden layers and the number of neurons. These parameters varied for each volunteer and for each class configuration, aimed at obtaining the best classification accuracies. Usually, 2 or 3 hidden layers were enough, but the number of neurons varied from 9 to 100 depending on the case. Englehart et al. (1999) and other researchers such as Basu, Battacharyya and Kin (2010) and Zhang (2000) defend that MLP, as long as properly trained and with an appropriate configuration will always match, if not exceed, the performance of an RLDA. But usually, due to the need to automate MLP training over a large number of interactions, the number of hidden layers and also the number of neurons are fixed. For a given subject and a specific number of classes however, the configuration may be inappropriate, and will be inhibit the generalization performance of the MLP. The RLDA, on the other hand does not require these specifications, and performs very well. + +![](figure) + +![](figure) + +## 5 CONCLUSIONS + +This study showed the same performance for RLDA and MLP in a problem of elbow angular position classification, based on the SME amplitude envelope. Both methods achieved average classification accuracies above 80% for a number of classes until 4 but individually, 5 subjects achieved similar results in a 5-class setup, which means a 20o shift between consecutive classes. May be a better classification accuracy can be reached with another feature instead of amplitude envelope that was used. However, this probably will also change the comparative performance between the methods. Considering that for MLP there is a great effort to define the architecture and also learning parameters, its use is only justified if there is a need of generalization that cannot be achieved by the RLDA that does not require the predefinition of parameters, it is practical and fast. + +# ACKNOWLEDGEMENTS + +The author thanks FEI and FAPESP for sponsoring. + +# REFERENCES + +Ahsan, Md. R., Ibrahimy, M. I., and Khalifa ,O. O. (2010). Advances in Electromyogram Signal Classification to Improve the quality of Life for the Disable and Aged People. J. Comput Sci., 6(7), 705-715. + +Basu, J. K., Bhattacharyya, D. and Kim, T. (2010). Use of Artificial Neural Network in Pattern Recognition. Int. J. Software Eng. And Its Applications, 4(2), + +Castro, M. C. F. (2011). Statistical Approach for Angular Position Separability Classes of EMG Data. Proc. ISSNIP Biosignals and Biorobotics Conferenc., Vitoria, Brazil. DOI: 10.1109/BRC.2011.5740663. + +Cheng, B. and Titterington, D. M. (1994). Neural Networks: A Review from a Statistical Perspective. Statistical Sci., 9(1), 2-30. + +Englehart, K., Hudgins, B., Parker, P. A., and Stevenson, M. (1999). Classification of the myoelectric signal using time-frequency based representations. Med. Eng. Phys. – Especial Issue on Intell. Data Anal. Electromyog. Electroneurog., 21, Jul., 431-438. + +Guo, Y., Hastie, T., and Tibshirani, R. (2007). Regularized linear discriminant analysis and its application in microarrays. Biostat., 8(1), 86-100. + +Hargrove, L. J., Englehart, K. and Hudgins, B. (2007). A Comparison of Surface and Intramuscular Myoelectric Signal Classification. IEEE Trans. Biom. Eng., 54(5), 847-853. + +Itakura, N., Kinbara, Y., Fuwa, T. and Sakamoto, K. (1996). Discrimination of Forearm’s Motions by Surface EMG Signals using Neural Network. Applied Human Science – J. Physiological Anthropology, 15(6), 287-294. + +Oskoei, M.A. and Hu, H. (2006). GA-based Feature Subset Selection for Myoelectric Classification. Proc. IEEE Int. Conf. Robotics and Biomimetics, China, 1465-1470. + +Parker, P., Englehart, K., and Hudgins, B. (2006). Myoelectric signal processing for control of powered limb prostheses. J. Electromyog and Kinesiol., 16, 541-548. diff --git a/outputs/multi_column/06df5e530c2ccb0310a3205586a37d4b9b7d_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/06df5e530c2ccb0310a3205586a37d4b9b7d_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..40b0b1b358ecc2a5c69194aca8c300b3ca93f990 --- /dev/null +++ b/outputs/multi_column/06df5e530c2ccb0310a3205586a37d4b9b7d_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +# CARTA DIRECTOR GENERAL + +La guerra de Ucrania ha ocupado nuestra atención durante todo 2022, y como organización humanitaria, Acción contra el Hambre ha estado presente, dentro y fuera de las fronteras del país apoyando a la población. Pero el conflicto ha tenido también impacto en España. Sus efectos se han sentido en el incremento de los precios en los mercados internacionales de materias primas, tanto energéticas como industriales y agrícolas. Todo ello se ha materializado en unas tasas de inflación muy altas, con especial incidencia en los productos de alimentación y en suministros básicos. Impactos que sufre directamente la población y que repercuten en su bienestar. Esta situación lleva a los hogares con menos recursos a tener, en muchos casos, que elegir entre una alimentación suficiente y adecuada o mantener sus viviendas a la temperatura necesaria. Hogares que, a pesar de haberse reducido la tasa de riesgo de pobreza o exclusión social AROPE en 2022, alcanzan al 26% de la población en España1. La escalada en los precios de alimentación ha afectado duramente a las personas en situación de carencia material y social severa (un 7,7%, esto es 3,65 millones de personas), de las cuales un 5,4% no pudieron permitirse una comida con carne, pollo o pescado cada dos días. Los últimos datos relativos a la seguridad alimentaria en España (julio 2020 a julio 2021) nos dicen que un 13,3% de los hogares españoles experimentaban algún nivel de inseguridad alimentaria; esto es casi 2,5 millones de hogares y, por tanto, en torno a 6.235.900 personas.2De estos hogares, el 5,2% sufre inseguridad alimentaria moderada o grave, es decir, casi un millón de hogares, que representan un total de 2.438.124 personas, han tenido que reducir su ingesta de alimentos por falta de recursos. Estas cifras nos indican que el problema de los hogares españoles para acceder a alimentos adecuados es estructural y no está únicamente ligado a crisis coyunturales. En Acción contra el Hambre hemos constatado que esta crisis de precios de los alimentos ha sido muy relevante entre las personas que participan en nuestros programas. En este sentido, la encuesta realizada en el marco del estudio “Innovación social en la inserción laboral: promoción de hábitos de vida saludable y su impacto en el empleo” nos muestra que el 53% de las personas participantes en nuestros programas de empleabilidad sufre algún nivel de inseguridad alimentaria, de las cuales, en torno al 10% estarían en una situación de privación alimentaria severa. Esta situación nos lleva a reflexionar sobre el cumplimiento del derecho a la alimentación en nuestro país3, y la necesidad de impulsar medidas y políticas públicas que nos permitan como país alcanzar los compromisos adquiridos con el Objetivo de Desarrollo Sostenible 2: “Hambre cero”. El ODS 2 recomienda a los países que hagan seguimiento de la inseguridad alimentaria, algo que, salvo alguna variable a través de la Encuesta de Condiciones de Vida que realiza el INE, no se está produciendo en España. En respuesta a ello, desde nuestra organización hemos puesto nuestro conocimiento y experiencia en el desarrollo de un sistema de alerta temprana que nos permita detectar el riesgo de inseguridad alimentaria y así anticiparnos para diseñar los programas e intervenciones adecuados. Pondremos este + +1Encuesta Condiciones de Vida, abril 2023. Datos referenciados a 2022. 2Moragues-Faus, Ana y Magaña-González, Claudia R. (2022). Alimentando un futuro sostenible: Estudio sobre la inseguridad alimentaria en hogares españoles antes y durante la COVID-19. Universidad de Barcelona y Fundación Daniel y Nina Carasso. 3Recogido en el Pacto Internacional de Derechos Económicos, Sociales y Culturales, y ratificado por España en 1977. + +sistema a disposición de otros agentes y de las instituciones encargadas del diseño de políticas públicas, con el objetivo de contribuir a alcanzar los compromisos del país y mejorar la vida de las personas. Asimismo, en Acción contra el Hambre apoyamos la idea de que el empleo decente es una herramienta esencial para luchar contra la inseguridad alimentaria y la desigualdad social. La capacitación de las personas para que accedan y se mantengan en el mercado laboral es clave. Ofrecer protección social a las personas más vulnerables será esencial para su integración. Por ello, durante todo 2022, desde nuestra organización hemos trabajado en estos dos ámbitos: inserción sociolaboral y seguridad alimentaria. Desde nuestros programas apoyamos a personas en riesgo de exclusión social que están en búsqueda de empleo o que quieren emprender un negocio nuevo. Apoyamos a personas con situaciones y perfiles diferentes a través de programas específicos, destaca que el 70% son mujeres. Además, acompañamos a jóvenes en busca de su primera oportunidad laboral, con personas migrantes y con personas en situación de desempleo de larga duración. Durante 2022, hemos apoyado a cerca de 6000 personas a encontrar un empleo o a emprender. 1827 personas han encontrado un empleo con nuestro apoyo, superando una ratio media de inserción del 40%. Especialmente relevante ha sido el resultado logrado de inserciones laborales de las personas mas vulnerables en el Programa de Escuelas de Empleo, donde se ha alcanzado un 35%. + +El escalado de VIVES EMPLEA SALUDABLE ha sido un hito de 2022, alcanzando a 674 personas y permitiéndonos afianzar este modelo que se constituye en nuestra apuesta por alcanzar un doble impacto en las personas: mejorar su empleabilidad y su salud, uniendo los componentes de inserción laboral y los de alimentación y hábitos de vida saludables. Este año ha supuesto la recuperación de la actividad de emprendimiento, afectada por la crisis de la COVID-19, ya que con nuestro acompañamiento se hayan creado 158 negocios y desarrollado 295 planes de empresa, cifras que duplican las de 2021. Seguimos apostando por la digitalización y modelos de negocio sostenibles mediante el enfoque de circularidad, lo que nos posiciona como una alternativa interesante para la población más joven. Finalmente, quiero incidir en nuestra disposición para contribuir a alcanzar los objetivos de la Agenda 2030, avanzar en un mayor bienestar para el conjunto de la ciudadanía y disminuir las brechas sociales que dificultan la recuperación y el crecimiento. + +![](figure) + +OLIVIER LONGUÉ Director General de Acción contra el Hambre diff --git a/outputs/multi_column/06df5e530c2ccb0310a3205586a37d4b9b7d_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/06df5e530c2ccb0310a3205586a37d4b9b7d_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e14552a455acf2ccf22e808af4eb8aa0553ba1ae --- /dev/null +++ b/outputs/multi_column/06df5e530c2ccb0310a3205586a37d4b9b7d_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,117 @@ +# MISIÓN, VISIÓN Y PRINCIPIOS + +### QUIÉNES SOMOS + +Acción contra el Hambre es una organización humanitaria internacional que lucha contra las causas y los efectos del hambre. + +Salvamos la vida de niños y niñas desnutridos. Garantizamos acceso a agua segura, alimentos, formación y cuidados básicos de salud. Hacemos posible que niños, mujeres y hombres se liberen de la amenaza del hambre. + +Desde 2012, trabajamos en España para favorecer la inclusión sociolaboral de las personas en riesgo de exclusión generando oportunidades a través de acciones de emprendimiento y empleabilidad. Dotamos a las personas de las capacidades y competencias necesarias para crear un negocio o trabajar por cuenta ajena y garantizarse así un medio de vida que les aleje de la pobreza y la exclusión. + +### NUESTRA VISIÓN + +UN MUNDO SIN HAMBRE. + +### NUESTROS VALORES + +Nuestros valores están centrados en el ADN de las personas que trabajan en la organización, en cómo nos vemos, cómo nos ven, y qué buscamos a la hora de trabajar en Acción contra el Hambre. + +###### INNOVACIÓN + +Creamos soluciones más eficaces a los problemas a los que nos enfrentamos. + +###### RIGOR + +Buscamos continuamente la excelencia. + +###### AGILIDAD + +Trabajamos de manera dinámica, en constante evolución y adaptación al cambio. + +###### EMPATÍA + +Escuchamos y nos identificamos con todas las personas para avanzar, juntos, en la construcción de un futuro sostenible. + +### DONDE QUIERA QUE ACTUEMOS, RESPETAMOS ESTOS PRINCIPIOS + +###### INDEPENDENCIA + +Nuestras intervenciones no obedecen a políticas nacionales ni internacionales, ni responden a los intereses de ningún gobierno. Actuamos de conformidad con nuestros propios principios para preservar nuestra independencia moral y económica. + +###### NEUTRALIDAD + +Una víctima es siempre una víctima. En Acción contra el Hambre mantenemos una estricta neutralidad política y religiosa. No obstante, siempre denunciaremos las violaciones de derechos humanos y los obstáculos interpuestos a la acción humanitaria. + +###### TRANSPARENCIA + +En Acción contra el Hambre actuamos con total transparencia. Proporcionamos a nuestros socios, donantes y beneficiarios, información clara sobre la asignación y utilización de nuestros fondos y ofrecemos garantías de buena gestión. + +###### ACCESO LIBRE Y DIRECTO A LAS VÍCTIMAS + +En Acción contra el Hambre demandamos acceso libre a las víctimas y control directo de nuestros propios programas. Denunciamos e intervenimos contra cualquier obstáculo que lo impida. Verificamos la asignación de nuestros recursos para garantizar que llegan a las personas adecuadas. En ningún caso las organizaciones con las que nos asociamos se convertirán en beneficiarias finales de nuestros programas. + +NO DISCRIMINACIÓN En Acción contra el Hambre rechazamos toda discriminación por razón de sexo, raza, etnia, religión, nacionalidad, ideología o clase social. + +###### PROFESIONALIDAD + +En Acción contra el Hambre nos comprometemos a trabajar con la máxima profesionalidad en todos los aspectos de nuestros programas, desde su diseño hasta su ejecución, pasando por la gestión y la evaluación. Construimos sobre años de experiencia y buscamos la mejora constante. + +# NUESTRO IMPACTO EN LOS OBJETIVOS DE DESARROLLO SOSTENIBLE - AGENDA 2030 + +El trabajo de Acción contra el Hambre en España está comprometido con una acción colectiva, inclusiva y global. Es nuestro firme compromiso mejorar la vida de las personas que más lo necesitan y no dejar a nadie atrás, y de esta manera contribuir a la consecución de los objetivos de la Agenda 2030 para el Desarrollo Sostenible y al logro de dichos Objetivos de Desarrollo Sostenible (ODS). + +Nuestro trabajo de mejora de la empleabilidad y apoyo al emprendimiento, con un enfoque de vida saludable y promoviendo la seguridad alimentaria entre las personas participantes, está estrechamente alinado con el ODS Hambre Cero (2) y Trabajo decente y crecimiento económico (8). Además, contribuimos en la consecución de Fin de la pobreza (1), Igualdad de Género (5), Reducción de las desigualdades (10) y Acción por el clima (13). + +Nuestro trabajo en España durante este año 2022 sigue impactando en las tres dimensiones del desarrollo sostenible: inclusión social, crecimiento económico y sostenibilidad medioambiental. + +A pesar de las consecuencias económicas afectadas aún por la pandemia COVID-19 y potenciadas por la inflación derivada del conflicto en Ucrania, las decisiones de cadenas distribuidoras y el encarecimiento de la producción, más del 40% de las personas que participaron en nuestros programas de empleo en 2022 han conseguido un puesto de trabajo, y hemos apoyado la creación de 145 nuevas iniciativas de negocio y el mantenimiento de aquellos creados en ejercicios anteriores. + +Fieles a nuestro compromiso, ante las necesidades detectadas en España en este año 2022, hemos seguido promoviendo una estrategia de seguridad alimentaria que combina investigación, apoyo a políticas públicas, sensibilización y programas con enfoque de salud. Desde 2020, hemos ofrecido recursos económicos a 2284 personas garantizando no solo el acceso a alimentos, sino también capacitación para mejorar la calidad de su dieta. Hemos podido constatar una mejora del 12,8% de la diversidad alimentaria en los hogares impactados. + +FIN DE LA POBREZA + +#### 1 + +![](figure) + +HAMBRE CERO + +##### 2 + +● + +#### 5 + +IGUALDAD DE GÉNERO + +![](figure) + +## 8 TRABAJO DECENTE + +Y CRECIMIENTO ECONÓMICO + +● + +#### 10 + +REDUCCIÓN DE LAS DESIGUALDADES + +■ + +#### 13 + +ACCIÓN POR EL CLIMA + +![](figure) + +Contribuimos al fin de la pobreza a través de nuestros programas de mejora de la empleabilidad y apoyo al emprendimiento. + +Combatimos contra las causas y las consecuencias de la inseguridad alimentaria en España con nuestro sistema de transferencia monetaria Tarjeta de Ayuda Solidaria. + +Empoderamos a las mujeres como pieza clave para el desarrollo. + +Promovemos la empleabilidad y el emprendimiento inclusivo. + +Trabajamos para borrar las diferencias e injusticias que se interponen en el acceso al empleo. + +Aumentamos y promovemos la creación de empleos sostenibles y circulares que potencien el cuidado del medio ambiente. diff --git a/outputs/multi_column/07070be1377058b90fd5fce677361eda4e3f_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/07070be1377058b90fd5fce677361eda4e3f_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7c656d9b21beeb99515d68074ee9328426ce89ea --- /dev/null +++ b/outputs/multi_column/07070be1377058b90fd5fce677361eda4e3f_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,56 @@ +| | covered (K pix) | rendered (K pix) | overdraw | vertex (ms) | geometry (ms) | raycasting (ms) | lighting (ms) | shadow (ms) | texturing (ms) | Total (ms) | Ratio | +| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | +| GL | | 249 | 0% | 0.40 | - | - | 0.33 | 0.06 | 0.45 | 1.25 | 100% | +| ST | 308 | 173 | 78% | 0.41 | 0.57 | 0.13 | 0.34 | 0.57 | 0.24 | 2.25 | 180% | +| PT | 406 | 197 | 106% | 0.41 | 0.69 | 0.16 | 0.39 | 0.70 | 0.17 | 2.52 | 202% | +| SQ | 897 | 173 | 418% | 0.41 | 0.40 | 0.33 | 0.44 | 0.26 | 0.36 | 2.20 | 176% | +| PQ | 714 | 181 | 294% | 0.40 | 0.36 | 0.29 | 0.42 | 0.22 | 0.37 | 2.06 | 165% | +| Lens1 | 5089 | 172 | 2859% | 0.40 | 0.47 | 2.55 | 0.53 | 0.61 | 0.65 | 5.21 | 417% | +| Lens2 | 5006 | 172 | 2810% | 0.40 | 0.44 | 2.00 | 0.79 | 0.49 | 0.62 | 4.74 | 379% | +| 600 | 702 | 181 | 288% | 0.39 | 0.16 | 0.26 | 0.44 | 0.17 | 0.13 | 1.55 | 128% | +| 2800 | 714 | 181 | 294% | 0.40 | 0.36 | 0.29 | 0.42 | 0.22 | 0.37 | 2.06 | 165% | +| 4900 | 786 | 182 | 332% | 0.45 | 0.52 | 0.29 | 0.43 | 0.27 | 0.49 | 2.44 | 185% | +| Temple PQ | 1950 | 250 | 680% | 0.17 | 0.33 | 0.77 | 0.63 | 0.42 | 0.57 | 2.88 | 461% | +| Patio PQ | 1271 | 335 | 279% | 7.55 | 31.47 | 0.86 | 0.24 | 5.93 | 38.28 | 79.85 | 600% | + +Table 3: Rendering times for our algorithm, with the cost of the different steps. The first 7 lines are for the Facade scene (2800 triangles), for several projection methods: GL (standard GLSL rendering with per pixel lighting), Sx is Spherical map; Px is Parabola map; xT uses triangles enclosing shape; while xQ uses quad bounding box. The next three lines are for Facade with different scene complexity for the PQ algorithm. The last two lines are for larger scenes. + +## 6 Conclusion and Future Directions + +In this paper, we have presented a robust algorithm for handling specific non-linear projections inside the graphics pipeline. Our algorithm works both for direct display of the non-linear projection, e.g. a fish-eye lens inside a video game, or for indirect use, e.g. when rendering a shadow map with a paraboloid projection. + +As with previous work, we start by bouding the projection of each shape, then discard extra fragments inside the bounding shape. Our contributions are twofold. First: two different methods for bounding the non-linear projections, one based on triangles that is optimal in fragments but requires more work in the geometry engine, the other based on quads that is optimal for the geometry engine but can causes more overdraw. Second: a mathematical analysis of several non-linear projection methods, where we show that some of them have simple expressions, and thus lend themselves to easy bounding through geometric tools. + +Although non-linear projections are slower than linear projections, the extra cost is manageable. As a single non-linear projection can replace up to five linear projections (in a hemicube), it can even be a practical alternative, both for rendering time and memory cost. + +# Acknowledgements + +The authors wish to thank the anonymous reviewers for their valuable comments. Nicolas Holzschuch is currently on a sabbatical at Cornell University, funded by the INRIA. Part of this research was carried within the ARTIS research team; ARTIS is a research team of the INRIA Rhône-Alpes and of the LJK; LJK is UMR 5224, a joint research laboratory of CNRS, IN-RIA, INPG, U. Grenoble I and U. Grenoble II. This research was supported in part by the Région Rhône-Alpes, under the Dereve II and the LIMA research programs, and by the ANR under the ART3D program. Most 3D models used in this research were created by Laurence Boissieux. + +# References + +B, S., A, T., S, H.-P. 2002. Shadow mapping for hemispherical and omnidirectional light sources. In Computer + +Graphics International, Springer, 397–408. + +F, G. 2005. Caches multiples et cartes programmables pour un calcul progressif et interactif de l’éclairement global. PhD thesis, Université Lyon 1. + +H, W., S, H.-P. 1998. View-independent environment maps. In Graphics Hardware ’98. + +H, X., W, L.-Y., S, H.-Y., G, B. 2006. Real-time multi-perspective rendering on graphics hardware. In Rendering Techniques 2006: Eurographics Symposium on Rendering. + +K, J., L, J., A, T. 2004. Hemispherical rasterization for self-shadowing of dynamic objects. In Rendering Techniques 2004: Eurographics Symposium on Rendering 2004, 179–184. + +K, J. J., B, M. L. 2000. Fish-eye lens designs and their relative performance. In Current Developments in Lens Design and Optical Systems Engineering, SPIE, 360–369. + +L, S., S, H., K, J., L, J., A, T. 2007. Incremental instant radiosity for real-time indirect illumination. In Rendering Techniques 2007 (Proceedings of the Eurographics Symposium on Rendering), 277–286. + +L, J. H. 1772. Anmerkungen und Zusätze zur Entwerfung der Land- und Himmelscharten. + +L, D. B., G, N. K., T, D., M, S. E., M, D. 2006. Practical logarithmic shadow maps. In Siggraph 2006 Sketches and applications. + +L, D. B., G, N. K., Q, C., M, S. E., M, D. 2007. Practical logarithmic rasterization for low-error shadow maps. In Graphics Hardware 2007. + +M¨ , T., T, B. 1997. Fast, minimum storage ray-triangle intersection. Journal of Graphics Tools 2, 1, 21–28. + +O, B., B, M., ME, C. 2006. Practical implementation of dual paraboloid shadow maps. In ACM SIGGRAPH Symposium on Videogames, ACM Press, 103–106. diff --git a/outputs/multi_column/070ad839eef2587442b064a135bbf8cbea3d_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/070ad839eef2587442b064a135bbf8cbea3d_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..42fc6ee7d5ce730b465908a70d0496628a13fadf --- /dev/null +++ b/outputs/multi_column/070ad839eef2587442b064a135bbf8cbea3d_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,100 @@ +Table 1 Characteristics of patients according to gender + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Gender Female Male
Variables Variables Number of patientsTotal 971P
655 316
Age (years)42 (12)41 (12) 44 (12)0.001
Waist (cm)133 (14)129 (13) 141 (14)<0.001
MS661 (68%)429 (65%) 232 (73%)0.013
Type 2 diabetes247 (25%)147 (22) 100 (32%)0.002
PTH (pmol/l)5.8 (2.3)5.8 (2.3) 5.9 (2.4)0.597
25(OH)D (nmol/l)52 (22)54 (22) 50 (21)0.009
Magnesium (mmol/l)0.84 (0.07)0.84 (0.07) 0.85 (0.07)0.522
Calcium (mmol/l)2.35 (0.07)2.36 (0.07) 2.35 (0.07)0.024
Phosphate (mmol/l)1.09 (0.17)1.10 (0.16) 1.06 (0.17)<0.001
+ +Data are means (SD) for continuous variables and n (%) for categorical variables. + +women had a waist circumference >102 cm and >88 cm, respectively. In total 662 (68.1%) had MS (65.4% and 73.3% for women and men, respectively, p = 0.013). Of the 246 patients who had T2DM 241 (98%) also had MS. + +## Path model estimation + +We first performed a path analysis of the model in Figure 1 separately for men and women as a preliminary analysis to explore possible gender differences. Besides an apparent gender difference in the direct effects of age on both PTH and MS, and in the direct effect of PTH on MS, also phosphate showed a possibly significant gender difference in the direct path to MS (data not shown). Parameters for these possible gender differences were included along their respective paths in the overall path model, resulting in a model with reduced DIC compared to a model without such gender differences (from 7182 to 7172). Removing statistically non-significant direct paths from this larger model reduced the DIC further (from 7172 to 7142). Regression results from this final, optimal model, expressed as standardized regression coefficients and CrIs, are shown in Table 2. Unstandardized results are included for reference. + +## MS + +Besides diabetes and age, only PTH and phosphate had significant direct effects on MS. The effect of T2DM was by far the strongest, while the estimated direct effect of PTH was 0.36 (95% CrI [0.15,0.57]). This value implies that a 1 SD increase in PTH (2.3 pmol/l) results in an increase of 0.36 in the log odds of MS. Due to a significant gender difference, this direct effect of PTH on MS was significant for women only. Direct effects of age and phosphate were 0.31 (95% CrI [0.13,0.50]) and 0.28 (95% CrI [0.10,0.47]), respectively, implying that an increase in 1 SD in age or phosphate (12 years and 0.17 mmol/l, respectively) results in an increase in the log OR of MS by approximately one third. Due to significant gender differences, these direct effects on MS were also only significant for women. Even though the 95% CrI for the gender difference for age on MS included zero, removing this gender effect from the model actually resulted in a model with an increased DIC, arguing for keeping it in the model. + +## PTH + +All proposed explanatory variables of MS had significant direct effects on PTH. As a consequence, they all have significant indirect effects on MS for women. The strongest direct effects on PTH were vit D and phosphate; -0.27 (95% CrI [-0.33,-0.21]) and -0.26 (95% CrI [-0.32,-0.20]), respectively. This value implies that an increase of 1 SD in vit D or phosphate (22.0 nmol/l and 0.17 mmol/l, respectively) corresponds to a mean decrease of approximately one fourth SD in PTH (-0.58 pmol/l). However, phosphate also has an indirect effect on PTH, mediated through calcium. The direct effect of phosphate on calcium is 0.27 (95% CrI [0.21, 0.33]), while the direct effect of calcium on PTH is -0.09 (95% CrI [-0.15,-0.04]). The total effect of phosphate on PTH is thus -0.26+(-0.09)*0.27 = -0.28; about a 10% increase compared to the direct effect alone. While the effect of phosphate on PTH, and in result MS, is partly mediated through calcium, the effect of magnesium on MS is mediated through both PTH and T2DM. Due to T2DM being a binary outcome along one of the pathways, this total effect cannot be quantified. The direct effect of age on PTH was 0.20 (95% CrI [0.13,0.27]). For the direct effect of age on PTH there was also a significant gender effect, resulting in this direct effect of age being significant for women only. For women, the total effect of age on MS is thus split into a direct path and two indirect paths; one via T2DM and one via PTH. + +## MS, PTH and gender differences + +A summary of the statistically significant paths for men and women is presented in Figure 2, while Table 3 summarizes the direct and indirect effects the various proposed explanatory variables has on MS. + +## Discussion + +Previous reports have addressed the effect of PTH on MS, and discussed whether the variable should be adjusted for when estimating the effect of other possible predictors of MS [14-17]. Our path analysis on morbidly obese subjects suggests a possible mediating role of PTH in the association between MS and various demographic variables and biomarkers. Significant gender differences indicate, however, that this mediating effect is only significant for women. diff --git a/outputs/multi_column/075cc4e94eb8bdd518b96fc27aaef00a64c8_page_11_pg1_pg1_repeat1.md b/outputs/multi_column/075cc4e94eb8bdd518b96fc27aaef00a64c8_page_11_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e7d30cf66e96b4da84c7886c938a8f0326bde9c0 --- /dev/null +++ b/outputs/multi_column/075cc4e94eb8bdd518b96fc27aaef00a64c8_page_11_pg1_pg1_repeat1.md @@ -0,0 +1,35 @@ +# Clinical Pearl + +With Chlamydia conjunctivitis, find out if the patient has been exposed to domesticated birds, particularly parakeets. A sizeable number of U.S. parakeets carry the Chlamydia organism in their bodies as Chlamydia psittacosis, which causes a clinically identical picture to sexually transmitted disease. Treatment is the same: one 1000-mg dose of oral azithromycin. + +ampicillin (various), amoxicillin, amoxicillin/clavulanate potassium (Augmentin, GlaxoSmithKline) or a second-generation cephalosporin such as cefuroxime (Ceftin, GlaxoSmithKline). + +![](figure) + +## Adult Inclusion Conjunctivitis (Chlamydia): Diagnosis + +Adult inclusion conjunctivitis, caused by Chlamydia, often manifests as a lingering, low-grade red eye with scant mucous discharge. The patient may have been self-treating for some time. Often, these cases are seen on referral from a general practitioner who treated the patient unsuccessfully with a topical eye drop that did not resolve the condition. In reviewing the signs and symptoms, this patient may seem to have both a viral and a bacterial infection at the same time. A key point in the differential diagnosis is the asymmetry of the follicles between the two eyes. With fluorescein staining, one eye may have giant inferior follicles, while the other eye has a limited follicular response, if any. One may also see a very inflamed upper tarsal conjunctiva with papillary hypertrophy once the upper lid is everted. If Chlamydia is suspected, it is important to ask if the patient has changed sex partners or had a new sex partner in the last few months. The patient may also have noticed burning on urination, although as many as 50% of those with Chlamydia are asymptomatic. Many optometrists are uncomfortable asking such personal questions, but there is no need to be embarrassed about clinically relevant details. One approach is to tell the patient that you suspect he or she has a sexually transmitted disease, so the questions don’t seem out of the ordinary. Another + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +Giant follicles to the inferior palpebral conjunctiva classic for chlamydial conjunctivitis. + +approach is to thoroughly review systems, starting at the top with headaches, moving on to upper respiratory and breathing problems, gastrointestinal issues, and sexual partners/urination. + +## Adult Inclusion Conjunctivitis (Chlamydia): Management + +![](figure) + +Adult inclusion conjunctivitis is the ocular manifestation of a systemic condition; it must be addressed with systemic medication. There is no need for topical therapy, other than artificial tears if desired. Key to successful management of Chlamydia conjunctivitis is concurrent treatment of both sexual partners so that they don’t re-infect one another. For compliance and efficacy, the ideal treatment is a single 1000-mg dose of oral azithromycin,34 although 3- and 5-day courses of azithromycin have also been shown clinically to be effective.35 It is incumbent upon us to coordinate the management of this condition with the patient’s gynecologist or personal physician. Chlamydia is one of the leading causes of female infertility. Our patients—and their sexual partners—need medical care and counseling for the non-ocular aspects of this sexually transmitted disease. Chlamydia should also be reported to the local health department, which can be done online on a state-by-state basis. + +![](figure) + +![](figure) + +![](figure) diff --git a/outputs/multi_column/075cc4e94eb8bdd518b96fc27aaef00a64c8_page_13_pg1_pg1_repeat1.md b/outputs/multi_column/075cc4e94eb8bdd518b96fc27aaef00a64c8_page_13_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1d76ce965da56c3f29fd5d13351218298f795e04 --- /dev/null +++ b/outputs/multi_column/075cc4e94eb8bdd518b96fc27aaef00a64c8_page_13_pg1_pg1_repeat1.md @@ -0,0 +1,35 @@ +![](figure) + +![](figure) + +Classic case of PKC with inferior phlyctenules. + +can restore ocular surface health are misleading because this has not been demonstrated by substantial evidence or clinical experience. AzaSite is indicated for the treatment of bacterial conjunctivitis. Another older antibiotic, doxycycline, also has some documented anti-inflamma-tory properties, but it is not considered a substitute when a steroid is indicated. Patients with blepharitis often have dry eye syndrome as well, in which case the anti-inflam-matory component of a combination drop can also be beneficial in treating the dry eye. + +![](figure) + +# PKC: Diagnosis + +![](figure) + +Phlyctenular conjunctivitis (PKC) is seen most commonly as a secondary condition in young girls with staphylococcal blepharitis, although it may also be caused in rare cases by tuberculosis. Patients will present with a scratchy, foreign body sensation, ocular redness and sectoral rather than generalized conjunctival injection, mimicking episcleritis. There is typically no discharge. PKC may be unilateral, but there is usually some involvement bilaterally. Although phlyctenular conjunctivitis can occur without obvious associated disease, patients with phlyctenules may exhibit concurrent evidence of either dermatologic or systemic disease. In adults, phlyctenules may be associated with rosacea, secondary to dry eye and staphylococcal blepharitis. If the eyelid appears healthy and there is no evidence of staphylococcal blepharitis, you should query the patient about breathing problems, and perhaps even obtain a chest X-ray to rule out tuberculosis. + +![](figure) + +![](figure) + +# PKC: Management + +Therapy depends on etiology. In individuals who are suspected of having tuberculosis, diagnosis should make use of a purified protein derivative (PPD) skin test, chest radiograph, and sputum cultures if necessary. These individuals should be referred for comanagement to their primary physician or to an infectious disease specialist. Though antituberculin agents are systemically administered, the ocular lesions are appropriately treated with topical steroids. In most instances, patients respond to a potent topical corticosteroid q.i.d. for three to four days, and subsequently tapered according to the clinical response. When patients are suspected of having underlying staphylococcal disease, both inflammatory and bacterial components can be managed with a combination antibiotic-steroid such as Zylet. Initial doses should be administered every 2 to 4 hours, depending on severity, for the first + +24 to 48 hours, then four times daily after that. In most instances, patients obtain dramatic relief from symptoms and can diminish use of the drug in 7 to 10 days. If the patient is experiencing significant pain and discomfort, a steroid ointment such as Lotemax ointment at night, in addition to the antibiotic/ steroid combination during the day, can help to relieve inflammation and pain. Because of the association of Staphylococcus with eyelid disease, lid therapy should be instituted. Antibiotic ointments such as bacitracin or bacitracin–polymyxin B can be used twice daily in conjunction with warm compresses and eyelid scrubs. The tetracyclines are effective in treating phlyctenular keratoconjunctivitis. Doxycycline, 100 mg twice daily for 4 to 6 weeks, is another common therapy. When other etiologic agents, such as intestinal parasites, Chlamydia, gonococci and HSV are suspected, patients should receive appropriate systemic medications. + +![](figure) + +## Non-Specific Inflammatory Conjunctivitis: Diagnosis + +Patients may present with low- to moderate-grade conjunctival injection. Typically, they will say their eye “doesn’t feel right” or perhaps friends have said their eyes look red. The eye is a little red and irritated but not bothering the patient too + +![](figure) + +![](figure) diff --git a/outputs/multi_column/07619750fcfe3caff8ec82642ac2449b490a_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/07619750fcfe3caff8ec82642ac2449b490a_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5feda00704525f34dae3821afb3791d4d3284af2 --- /dev/null +++ b/outputs/multi_column/07619750fcfe3caff8ec82642ac2449b490a_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,41 @@ +# Uusi haaste Suomessa: Miten suojaamme tuotantosiipikarjaa maassa jo esiintyvältä taudilta? + +Suomalaisen siipikarjan hyvän tautitilanteen ansiosta virustartuntojen uhka on kohdistunut meille pääsääntöisesti maamme rajojen ulkopuolelta. Elinkeino on suunnannut vastustustoimia jalostusaineksen maahantuontiin yli lakisääteisten määräysten. Keväisin on muuttolintuaikaan siipikarjan ulkonapitoa rajoitettu viranomaismääräyksin lintuinfluenssan ja muiden tartuntojen pelossa. Nyt ollaan uudessa tilanteessa, kun Suomeen hiipinyt uusi tauti, tarttuva keuhkoputkentulehdus eli Infectious Bronchitis (IB), näyttää löytäneen harrastesiipikarjatiloilta otollisen maaperän leviämiselleen, eikä sitä enää pystytä nopein toimin maasta hävittämään. + +#### Tautisuojaus on taas kunniassa + +Tuotantosiipikarjanäytteitä on viime viikkoina tutkittu tehostetusti IB:n varalta. Kaikki nämä näytteet ovat olleet negatiivisia, joten voidaan olettaa, että Suomen tuotantosiipikarjayksiköt ovat IB-tartun-nasta vapaita. Tuotantosiipikarjan suojaaminen tartunnalta, joka jo esiintyy omassa maassamme, on uudenlainen haaste. Siitä selvitään vain ehdottoman tiukalla tautisuojauksella. Jokaisen on nyt syytä tarkastella päivittäisiä rutiinejaan kriittisesti ja ryhtyä korjaaviin toimenpiteisiin, mikäli puutteita löytyy. + +- Tehostettu tautisuojaus kaikilla tuotantosiipikarjatiloilla. + +- Tautisulku ja sen oikeaoppinen käyttö on viimeistään nyt saatava rutiiniksi kaikilla tiloilla! + + - Kaikkea kontaktia harrastesiipikarjaan ja luonnonvaraisiin lintuihin on vältettävä. + + - Uudet linnut hankitaan vain siipikarjan terveystarkkailuun kuuluvilta tiloilta, jotka on todettu IBvapaiksi. + + - Siipikarja maahantuodaan ETT:n ohjeiden mukaisesti. Karanteeniaikana linnut tutkitaan IB:n varalta. + +- Kaikkiin epäilyttäviin oireisiin on heti reagoitava: lintuja ei myydä eteenpäin eikä munia toimiteta pakkaamolle, mikäli linnuilla on oireita. Otetaan yhteyttä eläinlääkäriin ja munapakkaamoon ja ryhdytään selvittämään tilannetta tutkimuksin. + +- Rokotuksiin IB:n varalta ei ole tarpeen ryhtyä, mikäli tartuntaa ei todeta tuotantokanaloissa. + +![](figure) + +![](figure) + +Hannele Nauholz ETT:ltä muistuttaa jälleen kerran tautisuojauksen tärkeydestä. Yksi osatekijä siinä on tautisulku. Se on yksinkertainen toteuttaa ja silti tehokas. + +#### Rokotuskynnys on korkea + +Rokotevirukset saattavat myös aiheuttaa taudin oireita, ja rokotteiden epäasiallinen käsittely jopa levittää + +Tällä hetkellä Suomessa ei rokotevirusta tilalta toiselle. ole käytettävissä elävää vi- Taudinpurkauksia havaitaan rusta sisältäviä rokotteita IB: myös esim. rokotusten syysn varalta. Päätös niiden mah- tä tai toisesta epäonnistuttua + +dollisesta käyttöönotosta tuotantosiipikarjatiloilla tehdään jatkossa yhteisesti alan ja viranomaisten yhteistyönä. Rokotusten mahdollinen käyttöönotto vaatii huolellista valmistelua. Ne merkitsevät lisätyötä ja kustannuksia laajasti koko alalle (munan- (virusten muuntautumiskyky, rokotustekniikka, rokotteiden väärästä säilytyksestä tai muusta syystä johtuva rokotteiden tehon heikentyminen, parven epätasaisuus jne.). Harrastekanaloissa rokotus ei käytännössä ole mahdollista IB:n vastustamiseksi. + +tuotanto ja lihasiipikarjatuo- Myöskään naapurimaassamtanto), eikä kerran aloitettu- me Ruotsissa ei tartuntatilanja rokotuksia voida enää lo- teesta huolimatta rokoteta + +pettaa. Maissa, joissa IB-ro-kotukset ovat käytössä, ei tartunnan seuranta serologisin eli vasta-ainetutkimuksin enää ole mahdollista. + +harrastesiipikarjaa. diff --git a/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_13_pg1_pg1_repeat1.md b/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_13_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..993c124b2ae61ab28ec18a8ca1291c02470c6679 --- /dev/null +++ b/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_13_pg1_pg1_repeat1.md @@ -0,0 +1,39 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +FIG. 9 is a flow chart illustrating operations involved in a write operation to a memory element by speculative thread 203 in accordance with an embodiment of the present invention. If a space-time dimensioned version 510 does not exist, the system creates a space-time dimensioned version 510 in speculative heap 406 (step 902). The system also updates status word 504 to indicate that speculative thread 203 has written to the object if such updating is necessary (step 903). The system next writes to space-time dimensioned version 510 (step 904). Such updating is necessary if head thread 202 must subsequently choose between writing to both primary version 500 and space-time dimensioned version 510 or writing only to primary version 500 as is described above with reference to FIG. 7. + +FIG. 10 is a flow chart illustrating operations involved in a join operation between head thread 202 and a speculative thread 203 in accordance with an embodiment the present invention. A join operation occurs for example when head thread 202 reaches a point in the program where speculative thread 203 began executing. The join operation causes state associated with the speculative thread 203 to be merged with state associated with the head thread 202. This involves copying and/or merging the stack of speculative thread 203 into the stack of head thread 202 (step 1002). It also involves merging space-time dimension and primary versions of objects (step 1004) as well as possibly garbage collecting speculative heap 406 (step 1006). In one embodiment of the present invention, one of threads 202 or 203 performs steps 1002 and 1006, while the other thread performs step 1004. + +FIG. 11 is a flow chart illustrating operations involved in a join operation between head thread 202 and a speculative thread 203 in accordance with another embodiment of the present invention. In this embodiment, speculative thread 203 carries on as a pseudo-head thread. As a pseudo-head thread, speculative thread 203 uses indirection to reference space-time dimensioned versions of objects, but does not mark objects or create versions. While speculative thread 203 is acting as a pseudo-head thread, head thread 202 updates primary versions of objects. + +Extension to Additional Speculative Threads + +Although the present invention has been described for the case of a single speculative thread, the present invention can be extended to provide multiple speculative threads operating on multiple space-time dimensioned versions of a data object in parallel. + +Process of Setting Marking Bits + +FIG. 12 is a flow chart illustrating the process of setting a marking bit associated with a referenced field within an object in accordance with an embodiment of the present invention. First, the system receives a reference to the field within the object (step 1202). This reference may be a read or a write operation. (Note that in the case of an array object the field is an array element.) + +Next, the system identifies a marking bit associated with the field (step 1204). In one embodiment of the present invention, the system maintains a separate set of read marking bits 604 for the object to indicate that a read operation has occurred to the field, and a separate set of write marking bits 606 to indicate that a write operation has occurred to the field. In this embodiment, if the operation is a read operation, one of the read marking bits 604 is selected. Otherwise, one of the write marking bits 606 is selected. + +In one embodiment of the present invention, the marking bit is identified by performing modulo operation. For example, if the object includes N marking bits numbered 0, 1, 2, . . . , N-1 and M fields numbered 0, 1, 2, . . . , M-1, + +the system starts with a field number for the field, and applies a modulo N operation to the field number to produce a number for the associated marking bit. This modulo operation can be efficiently performed if N is a power of two because the modulo operation reduces to a simple bit mask operation that isolates the lower order bits of the field number. + +The selection a value of N for an object involves a tradeoff. If N is too small, there tends to be lot of aliasing and system performance suffers due to false rollbacks. If N is too large, a great deal of memory is used for marking bits which can cause cache performance to suffer. In one embodiment of the present invention, N=8. In another embodiment, N=16. + +In the case of an array object, the system applies a division operation to the array element number (field number) to identify the associated array element. For example, if the array object has N marking bits numbered 0, 1, 2, . . . , N-1 and M array elements numbered 0, 1, 2, . . . , M-1, the step of identifying the marking bit includes dividing the array element number by the ceiling of M/N to produce a number for the associated marking bit. If the ceiling of M/N is a power of two, the division operation can be accomplished by shifting the array index so that the most significant bits of the array index become the number for the associated marking bits + +The above-described mapping between array elements and marking bits for array objects associates consecutive array locations with a single marking bit. This ensures that not all of the marking bits are set by common block copy operations involving only a portion of the array. + +After the marking bit is identified, the marking bit is set (step 1206) and the reference is performed to the field (or array element) within the object (step 1208). + +In general the marking mechanism according to the present invention can be used in any application that must keep track of accesses to fields within an object. However, in one embodiment of the present invention, marking is performed for read operations by speculative thread 203. In another embodiment, marking is performed to write bits 606 during a write operation by speculative thread 203 and to read bits 604 during a read operation by speculative thread 203. + +After the marking bits have been set, if a head thread 202 subsequently performs a write operation to a field in the object, head thread 202 can identify the associated marking bit using the above-described modulo or division operations. Next, the marking bit is extracted for examination purposes using a special bit extract operation that is part of the instruction set of the underlying computer system. + +FIG. 13 illustrates how a marking bit number can be determined from a field number or an array element number in accordance with an embodiment of the present invention. The system starts with a field number or an array element number 1302. In the case of a field number, the system performs a modulo operation by masking off all but the lower order three bits of field number 1302 to produce a three bit index (1,0,0) that specifies a marking bit. In the case of an array index, the system performs a division operation by shifting array element number 1302 until only the three most significant bits (0,1,1) remain. + +FIG. 14 illustrates how a block transfer operation sets multiple marking bits in accordance with an embodiment of the present invention. The example illustrated in FIG. 14 includes an array of data elements 1402. These data elements are numbered 0, 1, 2, . . . , 31. FIG. 14 also includes an array of read bits 604. These read bits are numbered 0, 1, + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_14_pg1_pg1_repeat1.md b/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_14_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f677663dcb2193343d79ea797c04411d9564865b --- /dev/null +++ b/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_14_pg1_pg1_repeat1.md @@ -0,0 +1,59 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +2, . . . , 7. In the case of a block transfer operation 1404 that reads array elements seven through 21, the system first determines that read bits one through five must be set. Next, the system sets read bits one through five. Finally, the system performs the block transfer operation. + +Note that a typical block transfer operation accesses consecutive array elements and hence sets a consecutive block of read bits. A shift operation can be used in combination with a special byte shuffle operation provided by the underlying machine architecture to efficiently set a consecutive block of read bits. For example, the byte shuffle operation can be used to wrap around bits that overflow from the shift operation. + +The foregoing descriptions of embodiments of the invention have been presented for purposes of illustration and description only. They are not intended to be exhaustive or to limit the invention to the forms disclosed. Accordingly, many modifications and variations will be apparent to practitioners skilled in the art. Additionally, the above disclosure is not intended to limit the invention. The scope of the invention is defined by the appended claims. + +What is claimed is: + +1. A method for marking objects defined within an object-oriented programming system to keep track of accesses to fields within objects, wherein the method operates in a system that supports space and time dimensional execution, the system having a head thread that executes program instructions and a speculative thread that executes program instructions in advance of the head thread, the head thread accessing a primary version of the object and the speculative thread accessing a space-time dimensioned version of the object, comprising: + +receiving a reference to a field within an object; identifying a marking bit within the object that is associated with the field, each marking bit within the object being associated with a different subset of fields within the object; + +setting the marking bit, wherein setting the marking bit indicates that at least one field within the associated subset of fields has been referenced; and + +performing the reference to the field within the object; wherein the steps of identifying the marking bit and setting the marking bit take place for a read operation by the speculative thread. + +2. The method of claim 1, wherein the object includes N marking bits numbered 0, 1, 2, . . . , N-1 and M fields numbered 0, 1, 2, . . . , M-1, and wherein identifying the marking bit associated with the field includes starting with a field number for the field, and applying a modulo N operation to the field number to produce a number for the associated marking bit. + +3. The method of claim 2, wherein N is a power of two. + +4. The method of claim 1, wherein there exists a separate set of marking bits for write operations, and wherein if the reference is a write operation by the speculative thread, the steps of identifying the marking bit and setting the marking bit involve the separate set of marking bits, so that upon a subsequent write operation to the field by the head thread, the head thread writes to both the primary version and the space-time dimensioned version if the marking bit is unset, and writes to only the primary version if the marking bit is set. + +5. The method of claim 1, further comprising during a subsequent write operation to the field by the head thread, determining if the marking bit-associated with the field has been set by executing a special bit extract instruction to examine the marking bit. + +6. The method of claim 1, wherein if the object is an array object with N marking its numbered 0, 1, 2, . . . , N-1 and M array elements numbered 0, 1, 2, . . . , M-1, the step of identifying the marking bit that is associated with the field includes identifying an array index for an array element, and dividing the array index by the ceiling of M/N to produce a number for the associated marking bit. + +7. The method of claim 6, wherein the ceiling of M/N is a power of two and the division operation is accomplished by shifting the array index so that the most significant bits of the array index become the number for the associated marking bin. + +8. The method of claim 6, wherein if the reference involves a block transfer operation, the method further determines if the block transfer operation touches array elements associated with multiple marking bits, and if so sets the multiple marking bits. + +9. The method of claim 1, further comprising resetting marking bits within the object after a subsequent join operation or rollback operation. + +10. The method of claim 9, wherein the resetting occurs as part of a write operation that sets the marking bit associated with the referenced field. + +11. The method of claim 1, wherein all marking bits within the object are contained in a single word of memory that additionally contains a time stamp. + +12. A method for marking objects defined within an object-oriented programming system to keep track of accesses to fields within objects, the method operating in a system that supports space and time dimensional execution, the system having a head thread that executes program instructions and a speculative thread that executes program instructions in advance of the head thread, the head thread accessing a primary version of the object and the speculative thread accessing space-time dimensioned version of the object, the method comprising: + +receiving a reference to a field within an object, the reference being a read operation by the speculative thread; + +identifying a marking bit within the object that is associated with the field, each marking bit within the object being associated with a different subset of fields within the object, + +wherein the object includes N marking bits numbered 0, 1, 2, . . . , N-1 and M fields numbered 0, 1, 2, . . . , M-1, + +wherein identifying the marking bit associated with the field includes starting with a field number for the field, and applying a modulo N operation to the field number to produce a number for the associated marking bit, and + +wherein N is a power of two; + +setting the marking bit, wherein setting the marking bit indicates that at least one field within the associated subset of fields has been referenced; + +performing the reference to the field within the object; and + +resetting marking bits within the object after a subsequent join operation or rollback, operation, wherein the resetting occurs during a subsequent setting of a marking bit after the subsequent join operation or rollback operation. + +13. A computer readable storage medium storing instructions that when executed by a computer cause the computer to perform a method for marking objects defined within an object-oriented programming system to keep track of accesses to fields within objects, wherein the method oper- + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..636d5dce58a67fb958ab6b0c43fd77a8ea97928d --- /dev/null +++ b/outputs/multi_column/07c14b471fd33c56b988cc7a58dae211d16f_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,47 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +METHOD AND APPARATUS FOR PROVIDING FINER MARKING GRANULARITY FOR FIELDS WITHIN OBJECTS + +Related Application + +This application is related to the subject matter in a pending U.S. patent application, entitled "Supporting Space-Time Dimensional Program Execution by Selectively Versioning Memory Updates," by inventors Shailender Chaudhry and Marc Tremblay, having Ser. No. 09/313,229 and a filing date of May 17, 1999. + +The subject matter of this application is also related to the subject matter in a co-pending non-provisional application by the same inventor(s) as the instant application and filed on the same day as the instant application entitled, "Using Time Stamps to Improve Efficiency in Marking Fields Within Objects," having Ser. No. 09/327,399, and filing date Jun. 7, 1999. + +BACKGROUND + +1. Field of the Invention + +The present invention relates to performance enhancements in object-oriented programming systems. More specifically, the present invention relates to a method and an apparatus that supports finer marking granularity for fields within objects defined within an object-oriented programming system. + +2. Related Art + +As increasing semiconductor integration densities allow more transistors to be integrated onto a microprocessor chip, computer designers are investigating different methods of using these transistors to increase computer system performance. Some recent computer architectures exploit "instruction level parallelism," in which a single central processing unit (CPU) issues multiple instructions in a single cycle. Given proper compiler support, instruction level parallelism has proven effective at increasing computational performance across a wide range of computational tasks. However, inter-instruction dependencies generally limit the performance gains realized from using instruction level parallelism to a factor of two or three. + +Another method for increasing computational speed is "speculative execution" in which a processor executes multiple branch paths simultaneously, or predicts a branch, so that the processor can continue executing without waiting for the result of the branch operation. By reducing dependencies on branch conditions, speculative execution can increase the total number of instructions issued. + +Unfortunately, conventional speculative execution typically provides a limited performance improvement because only a small number of instructions can be speculatively executed. One reason for this limitation is that conventional speculative execution is typically performed at the basic block level, and basic blocks tend to include only a small number of instructions. Another reason is that conventional hardware structures used to perform speculative execution can only accommodate a small number of speculative instructions. + +What is needed is a method and apparatus that facilitates speculative execution of program instructions at a higher level of granularity so that many more instructions can be speculatively executed. + +One challenge in designing a system that supports speculative execution is to detect a rollback condition. A rollback + +condition can occur in a number of situations. For example, a rollback condition occurs when a speculative thread that is executing program instructions in advance of a head thread reads from a memory element before the head thread performs a write to the memory element. In this case, the speculative thread must "rollback" so that it can read the value stored by the head thread. A rollback condition can be detected by "marking" memory elements as they are read by the speculative thread so that the head thread can subsequently determine if the memory elements have been read by the speculative thread. Unfortunately, using a separate marking indicator for each memory element can consume a large amount of memory, which can reduce cache hit rates arid thereby degrade system performance. + +What is needed is a method and an apparatus for marking memory elements that does require a large amount of memory for storing marking indicators. + +SUMMARY + +One embodiment of the present invention provides a system that facilitates marking of objects defined within an object-oriented programming system to keep track of accesses to fields within the objects. The system operates by receiving a reference to a field within an object, and identifying a marking bit within the object that is associated with the field. Note that each marking bit within the object is associated with a different subset of fields within the object. Next, the system sets the marking bit to indicate that at least one field within the associated subset of fields has been referenced. Finally, the system performs the reference to the field. + +In one embodiment of the present invention, the object includes N marking bits numbered 0, 1, 2, . . . , N-1 and M fields numbered 0, 1, 2, . . . , M-1. In this embodiment, the system identifies the marking bit associated with the field by starting with a field number for the field, and applying a modulo N operation to the field number to produce a number for the associated marking bit. In a variation on this embodiment, N is a power of two. + +In one embodiment of the present invention, the system supports space and time dimensional execution. To this end, the system supports a head thread that executes program instructions and a speculative thread that executes program instructions in advance of the head thread. The head thread accesses a primary version of the object and the speculative thread accesses a space-time dimensioned version of the object. In this embodiment, the steps of identifying the marking bit and setting the marking bit take place for a read operation by the speculative thread. + +In a variation on this embodiment, there exists a separate set of marking bits for write operations. In this variation, if the reference is a write operation by the speculative thread, the steps of identifying the marking bit and setting the marking bit involve the separate set of marking bits. Upon a subsequent write operation to the field by the head thread, the head thread writes to both the primary version and the space-time dimensioned version if the marking bit is unset, and otherwise writes to the primary version. + +In one embodiment of the present invention, during a subsequent write, operation to the field by the head thread, the system determines if the marking bit associated with the field has been set by executing a special bit extract instruction to examine the marking bit. + +In one embodiment of the present invention, if the object is an array object with N marking bits numbered 0, 1, 2, . . . , N-1 and M array elements numbered 0, 1, 2, . . . , M-1, + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a21eb6b4460a5b963fdcc52e2885e6a34c9d9465 --- /dev/null +++ b/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +# Original Article + +# Incidences, Predictors, and Clinical Outcomes of Acute and Late Stent Malapposition Detected by Optical Coherence Tomography After Drug-Eluting Stent Implantation + +Eui Im, MD*; Byeong-Keuk Kim, MD*; Young-Guk Ko, MD; Dong-Ho Shin, MD; Jung-Sun Kim, MD; Donghoon Choi, MD; Yangsoo Jang, MD; Myeong-Ki Hong, MD, PhD + +Background—We investigated the incidences, predictors, and clinical outcomes of acute and late stent malapposition detected by optical coherence tomography (OCT) after drug-eluting stent implantation. Methods and Results—We analyzed the OCT images from 351 patients with 356 lesions who received poststent and followup OCT examinations. Acute stent malapposition was observed in 62% of lesions. Approximately half of the acute stent malappositions were located within the edges of the stents. Severe diameter stenosis, calcified lesions, and long stents were independent predictors of acute stent malapposition. Follow-up OCT examinations were performed 175±60 days after drug-eluting stent implantation. Thirty-one percent of lesions with acute stent malapposition remained malapposed (late-persistent stent malapposition) and were typically (72%) located within the edges of the stent. The location within the stent edges and the volume of acute stent malapposition were independent predictors of late-persistent stent malapposition. Acute stent malapposition with a volume >2.56 mm3 differentiated late-persistent stent malapposition from resolved acute stent malapposition. Late-acquired stent malapposition was detected in 15% of all lesions and was usually (61%) located within the stent body. Late-acquired stent malapposition was more frequently associated with plaque/thrombus prolapse on poststent OCT images (70% versus 42%; P<0.001). Clinical events, including cardiovascular death, nonfatal myocardial infarction, and stent thrombosis, did not occur in patients with late stent malapposition during the follow-up period of 28.6±10.3 months after drug-eluting stent implantation. Conclusions—Acute, late-persistent, and late-acquired stent malapposition had relatively high incidences but different predictors. The clinical outcome of stent malapposition was favorable. (Circ Cardiovasc Interv. 2014;7:00-00.) Key Words: coronary disease ◼ drug-eluting stents ◼ tomography, optical coherence + +![](figure) + +Coronary stent malapposition is the separation of ≥1 stent strut from the intimal surface of the coronary arterial wall without involvement of side branches.1 In the era of drugeluting stents (DESs), late-acquired stent malapposition is a well-recognized problem in interventional cardiology because it may constitute a potent substrate for late stent thrombosis.1–3 The incidence of late-acquired stent malapposition was reported to be as high as 25% in patients with acute myocardial infarction.4 In addition, predictors of late-acquired stent malapposition include plaque or thrombus absorption or positive vascular remodeling.1,5,6 Intravascular ultrasound (IVUS) imaging was used to detect stent malapposition in previous studies. IVUS may not completely detect stent malapposition because of limited axial resolution (100–200 μm) or stent-related artifacts.5 However, optical coherence tomography (OCT) with a higher resolution (12–18 μm) may detect stent malapposition with greater accuracy. There are limited data on detection of acute and late stent malapposition by OCT in small sample sizes. Therefore, we investigated the incidences, predictors, and clinical outcomes of acute and late stent malapposition detected by OCT in a large number of patients who received DESs. + +##### Study Population + +#### Methods + +Patients who received implantation of DESs for de novo coronary lesions between January 2009 and December 2011 with poststent and follow-up OCT were identified from the OCT registry database of our institute. Exclusion criteria included the following (1) the DES was implanted for left main coronary disease, (2) there were overlapping DESs implanted in the lesion, (3) the clinical follow-up period after DES implantation was <1 year, (4) follow-up OCT was performed >1 year after DES implantation, and (5) the OCT image had poor quality. Ultimately, 351 patients with 356 lesions were enrolled in this study. During the same study period, there were 3235 patients (3587 lesions) + +Received August 20, 2013; accepted December 15, 2013. From the Division of Cardiology, Severance Cardiovascular Hospital (E.I., B.-K.K., Y.-G.K., D.-H.S., J.-S.K., D.C., Y.J., M.-K.H.) and Severance Biomedical Science Institute (Y.J., M.-K.H.), Yonsei University College of Medicine, Seoul, Korea. *Drs Im and Kim contributed equally to this work. The Data Supplement is available at http://circinterventions.ahajournals.org/lookup/suppl/doi:10.1161/CIRCINTERVENTIONS.113.000797/-/DC1. Correspondence to Myeong-Ki Hong, MD, PhD, Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-gu, Seoul 120-752, Korea. E-mail mkhong61@yuhs.ac © 2014 American Heart Association, Inc. + +Circ Cardiovasc Interv is available at http://circinterventions.ahajournals.org 1 diff --git a/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7ea2e030304c3d31b2f52c0fa5c697f1aa98b3d9 --- /dev/null +++ b/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,37 @@ +## WHAT IS KNOWN + +- There are 3 types of stent malapposition: acute, late-persistent, and late-acquired stent malapposition. + +- Late-acquired stent malapposition may constitute a potent substrate for late stent thrombosis after drug-eluting stent implantation. + +- There are limited data on optical coherence tomography–detected acute and late stent malapposition in small sample sizes. + +## WHAT THE STUDY ADDS + +- Acute, late-persistent, and late-acquired stent malapposition detected by optical coherence tomography had relatively high incidences but different predictors. + +- The clinical outcome of optical coherence tomography–based stent malapposition was favorable. + +who underwent drug-eluting stents implantation because of stenosis of de novo lesions and 52 patients (55 lesions) with postintervention OCT alone, excluding 351 study patients. DESs were selected by operators at the time of implantation and included sirolimus-eluting stents (Cypher, Cordis, Miami, FL), zotarolimus-eluting stents (Resolute or Integrity, Medtronic, Santa Rosa, CA), everolimuseluting stents (Xience V, Abbott Vascular, Santa Clara, CA), or biolimus A9-eluting stents (Nobori, Terumo Corporation, Tokyo, Japan or Biomatrix, Biosensors International, Singapore). Each DES was implanted using conventional techniques. Unfractionated heparin was administered as an initial bolus of 100 IU/kg with additional boluses administered during the procedure to achieve an activated clotting time of 250 to 300 seconds. Dual antiplatelet therapy (aspirin and clopidogrel) was provided to each patient until the follow-up OCT was performed. The institutional review board of Yonsei University Severance Hospital approved this study, and written informed consent was obtained from each patient. + +![](figure) + +### OCT Imaging and Analyses + +OCT was performed using 2 OCT systems (Model M2 Imaging System and C7-XR Imaging System, LightLab Imaging, Inc, St Jude Medical, St. Paul, MN).7,8 All OCT images were analyzed at a core laboratory (Cardiovascular Research Center, Seoul, Korea) by analysts who were blinded to patient and procedural information. Cross-sectional OCT images were analyzed at 1-mm intervals. Stent and luminal cross-sectional areas were measured. The malapposition and neointimal hyperplasia (NIH) cross-sectional area was calculated as appropriate.9 Once a complete set of cross-sectional area measurements was obtained, intrastent volumes (stent, lumen, malapposition, and NIH volumes) were calculated by Simpson rule.10 NIH volume obstruction (%) was calculated as the NIH volume divided by stent volume. Mean values are reported. NIH thickness, the distance between the endoluminal surface of the neointima and the strut, was measured inside each strut with a line perpendicular to the neointima and strut.11 The percentage of malapposed struts in each stented lesion was calculated as the (number of malapposed struts/total number of struts in all cross-sections of the lesion)×100. A malapposed strut was defined as a strut that was detached from the vessel wall as follows: Cypher, ≥160 μm; Resolute or Integrity, ≥110 μm; Xience V, ≥100 μm; Nobori or Biomatrix, \(\geq130\mu m.^{12-14}\) A coronary stent malapposition that is detected immediately after implantation of the stent is classified as an acute stent malapposition, whereas one that is detected later (during a follow-up examination) is classified as a late stent malapposition. Late stent malappositions can be further classified as a late-persistent stent malappositions or late-acquired stent malappositions. A late-persistent stent malapposition is an acute stent malapposition that remains present at the follow-up examination. A late-acquired stent malapposition is a newly developed stent malapposition that is identified at the follow-up examination despite complete stent apposition during the initial procedure. If malapposed struts were detected by poststent OCT (ie, acute stent malapposition), each cross-section of the poststent OCT image was matched with corresponding cross-sectional images of the follow-up OCT image as accurately as possible based on the distance from fiduciary landmarks (eg, stent edges, side branches, or calcification).8 The lesions were then appropriately classified as resolved acute stent malapposition lesions with or without late-acquired stent malapposition or late-persistent stent malapposition lesions with or without late-acquired stent malapposition (Figure 1). In addition, the longitudinal locations of malappositions were classified as stent edges (<5 mm from the proximal or distal edge of the stent) or stent body. If malapposed struts were detected within a stent edge and stent body simultaneously, the location with the larger malapposition volume was designated as the longitudinal location of malapposition. + +### Angiographic Analyses + +Quantitative coronary angiography analyses were performed before and after stent implantation and at the follow-up using an off-line quantitative coronary angiographic system (CASS system, Pie Medical Instruments, Maastricht, The Netherlands) in an independent core laboratory (Cardiovascular Research Center, Seoul, Korea). Reference vessel diameters and minimal luminal diameters were measured with a guiding catheter for magnification-calibration from diastolic frames in a single, matched view that showed the smallest minimal luminal diameter. + +### Clinical Follow-up + +All patients were advised to receive dual (aspirin and clopidogrel) antiplatelet therapy for ≥6 months after DES implantation. During the follow-up period, clinical events were investigated, including cardiovascular death, nonfatal myocardial infarction, stent thrombosis, and target lesion revascularization. Patients who experienced clinical events within the first year after DES implantation were included in this study. + +### Statistical Analyses + +Categorical variables are presented as numbers (%). Continuous variables are presented as the mean±SD. Categorical variables were compared using \(\chi^{2}\) tests or Fisher exact tests. Continuous variables were compared using Student t tests, paired t tests, or 1-way ANOVA, as appropriate. If distributions were skewed, nonparametric tests were performed. Multivariate logistic regression analyses were performed to identify independent predictors of acute, late-persistent, and late-acquired stent malapposition. Variables with P values <0.2 from univariate analyses were included in multivariate analyses. Receiver-operating curve analyses were performed to identify the best cut-off value that separated late-persistent stent malapposition lesions from resolved acute stent malapposition lesions. The incidences of clinical events were presented as the proportions and compared using Fisher exact test because of the small number of clinical events. Statistical analyses were performed using the software program SPSS (version 20.0, Chicago, IL), and P<0.05 was considered statistically significant. + +# Results + +Baseline clinical and procedural characteristics are summarized in Table 1. There were no statistically significant differences in baseline clinical and procedural characteristics among the 351 study patients, 52 patients with post-DES OCT alone, and the remaining 3235 patients with DES implantation during the same study period (Table 1). Figure 2 shows the incidences of acute, late-persistent, and late-acquired stent diff --git a/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c892b9a456878dcfc769781ada4081ff118c7d4c --- /dev/null +++ b/outputs/multi_column/07f4d706dd1736e247163f0128702c65bdd8_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,242 @@ +Table 4. Predictors of Late-Acquired Stent Malapposition + +Univariate Analysis + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Late-Acquired Stent Malapposition Lesions (n=54)No Late-Acquired Stent Malapposition Lesions (n=302)
P Value
Follow-up optical coherence tomography
Time intervals after index procedure, days173±43175±630.841
Late-acquired malapposed struts, %3.8±4.50...
Maximum late-acquired stent malapposition cross-sectional area, mm20.95±0.900...
Late-acquired stent malapposition volume, mm32.06±3.240...
Late-acquired stent malapposition volume, % (of stent volume)1.7±3.10...
Late-acquired stent malapposition within stent body33 (61%)0...
Acute coronary syndrome*18 (33%)88 (30%)0.586
Dyslipidemia*34 (63%)155 (52%)0.144
B2- or C-type lesion24 (44%)132 (44%)0.745
Baseline diameter stenosis, %69±2065±140.299
Stent diameter, mm3.22±0.373.14±0.360.178
Stent length, mm19.0±5.418.9±5.10.955
Poststent optical coherence tomography
Plaque/thrombus prolapse38 (70%)128 (42%)<0.001
+ +*Analyzed in patient level. + +implantation. Neointimal healing reduces the volume of acute stent malapposition with many acute stent malapposition struts becoming completely integrated into the vessel wall. However, cases of acute stent malapposition with a large volume or acute stent malapposition located within the edges of the stent were not resolved in most cases. Thus, acute stent malapposition volume and location within stent edges were identified as independent predictors of late-persistent stent malapposition. Our results indicate that an acute stent malapposition with a larger volume or area is more likely to persist at follow-up examinations, which is consistent with findings from previous studies.4,6,8 Late-persistent stent malapposition could be differentiated from resolved acute stent malapposition by an acute stent malapposition area >1.2 mm2 according to an IVUS study.6 A strut-to-vessel distance ≤260 µm on poststent OCT images was suggested as a cut-off value for resolved acute stent malapposition.18 A volume of acute stent malapposition >2.56 mm3 best separated late-persistent stent malapposition lesions from resolved acute stent malapposition lesions in the present study. + +# Late-Acquired Stent Malapposition + +![](figure) + +The presence of a plaque/thrombus protrusion, which was most often (75%) located within the stent body on poststent IVUS images, was reported to be a predictor of late-acquired stent malapposition.6 Thus, it was suggested that plaque/ + +Incidences of Clinical Events and Duration of Dual Antiplatelet Therapy During Follow-up + +Table 5. + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
Both Late-Persistent and Late-Acquired Stent Malapposition (n=23)Late-Acquired Stent Malapposition Alone (n=31)Late-Persistent Stent Malapposition Alone (n=45)No Stent Malapposition (n=252)
Overall Patients (N=351)
P Value
Follow-up duration after PCI, mo28.6±10.324.3±4.327.7±10.028.4±9.229.1±10.80.175
Follow-up duration after follow-up22.8±10.418.4±4.422.0±10.422.6±8.923.3±10.90.180
OCT, mo
Composite of clinical events10 (2.9%)0 (0%)1 (3.2%)1 (2.2%)8 (3.2%)1.0
Cardiovascular death1 (0.3%)0 (0%)0 (0%)0 (0%)1 (0.4%)1.0
Nonfatal myocardial infarction1 (0.3%)0 (0%)0 (0%)0 (0%)1 (0.4%)1.0
Stent thrombosis0 (0%)0 (0%)0 (0%)0 (0%)0 (0%)1.0
Target lesion revascularization8 (2.3%)0 (0%)1 (3.2%)1 (2.2%)6 (2.4%)0.900
Duration of dual antiplatelet therapy, mo14.2±8.211.9±5.315.5±6.413.8±7.114.3±8.70.417
At least 12 mo of dual antiplatelet therapy262 (75%)15 (65%)27 (87%)36 (80%)184 (73%)0.199
diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_13_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_13_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ee8f0a617a5693fa9a91e2f59a6074aa896606e7 --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_13_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +# Producing Nanoporous Metallic Foams + +Producing nanoporous metals has been a difficult and, depending on the type of metal, elusive task. Recent discoveries by our team of researchers in the LANL Materials Dynamics Group have led to a method for achieving the combustion synthesis of nanoporous transition-metal foams that have ultralow densities and ultrahigh surface areas. (See “What are transition metals?” on page 15.) We have produced nanostructured metal foams of iron, cobalt, silver, and copper, and our nanofoam forming technique can be applied to many other metals. These materials offer a wide variety of potential applications in, for example, catalysis, fuel cells, and hydrogen storage. + +Nanofoam pore diameters are measured in nanometers, too small for the unaided human eye to distinguish. In fact, the finest flaxen human hair, at diameters of 17 to 50 μm, is close to the limit of resolution of the human eye. The smallest pores in our metal nanofoams are 10 to 20 nm in diameter, about a thousand times smaller. The largest pores, at 1 to 3 μm, are still too small to see. + +To produce a nanostructured metal foam, we ignite pressed pellets of high-nitrogen metal complexes in an inert atmosphere at different pressures. As a pellet rapidly burns, its volume dramatically increases; the burning complex releases heated metal atoms, which attract each other and coalesce into larger particles. At the same time, decomposition gases such as hydrogen and nitrogen, also released by the reaction, blow tiny holes through the coalescing metal to form nanoscopic pores. The resulting foams typically contain 50% to 70% metal, with the remainder being carbon nitride-type impurities that can be removed later by heat treatment. + +## Possible applications for our nanostructured metal foams abound, including catalysis, fuel cells, and hydrogen storage. + +The iron foam has the incredibly low density of 0.01 to 0.04 g/cm3. For comparison, ultralow-density aluminum foam has a density of 0.08 to 0.16 g/cm3. + +Our nanofoams have pore diameters of 10 to 20 nm to about 1 μm, surface area-to-mass ratios as high as 258 m2/g, and densities as low as 0.01 g/cm3. For comparison, silica aerogels, the lightest known + +![](figure) + +![](figure) + +Copper nanoporous material formed at 200 psi Ar (the production vessel is pressurized with argon) overpressure: + +(a) burn front is dark portion heading top to bottom and (b) heat treated to 500°C in hydrogen gas (15,000x, 200-nm scale bar). Illustration (a) shows the actual formation of copper foam from the copper complex; + +(b) scanning electron micrograph (SEM) of copper heat treated to form copper foam. diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_16_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_16_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9416150b602e070d8cf238544b6a7996d7802142 --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_16_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +a comparatively robust “cermet”(ceramic + metal) anode. Fortuitously, similar cermet catalyst systems have shown promise in NOx removal. + +The National Ignition Facility at Lawrence Livermore National Laboratory trains many intense pulsed laser beams on inertial confinement fusion (ICF) targets about the size of BBs. The targets contain fusion fuel—a frozen mixture of deuterium and tritium, two hydrogen isotopes. The laser beams heat and compress the fuel to the temperatures and densities required for fusion reactions to occur. Currently, an ICF target consists of a gold foam shell surrounding a nonporous shell filled with fusion fuel. To ensure that the shock waves generated at the target’s surface travel efficiently into its interior, a shell of high-z nanostructured metal foam, such as copper, should surround the target. However, fabricating copper foam shells with the desired qualities has so far been difficult. We hope that this process for producing nanostructured metal foams will yield the pore sizes and densities that are useful in ICF applications. + +Research is also under way to investigate the applicability of nanostructured copper and silver foams for the detection of explosives and other harmful agents using surface-enhanced Raman scattering (SERS). Raman spectroscopy can provide information about single molecules by detecting the light scattered inelastically from the molecules. The rather weak Raman effect is strengthened greatly when the molecules are attached to a metal substrate with roughness on the order of nanometers. It has been shown that extremely small quantities of various materials can be detected using SERS that employs nanostructured metal substrates. For example, SERS has been used to detect some environmental biological pollutants at levels as low as 0.1 ng. + +![](figure) + +![](figure) + +Schematic showing localization of illicit agent (green TNT molecule not to scale) into interstitial sites of metal foams for largest enhancements of Raman signal. The green hexagon is part of the TNT molecule. The yellow lines depict electronic effects occurring when a specific wavelength of light interacts with the metal, in turn leading to Raman signal enhancement when these electronic effects interact with the bound TNT. Cumulative electrostatic enhancements (yellow lines) from many surfaces could result when illicit substances (green TNT) bind into these sites. + +SERS relies on electromagnetic interactions between the molecule to be detected and the substrate to which the molecule is attached. Because of the nanostructured foams’ low densities, high surface areas, and stochastic structure, they appear to be ideal for SERS substrates. Materials of interest for SERS detection include chemicals as simple as glucose or as complex as anthrax as well as explosives. + +Our metal nanofoam forming technique shows promise as a flexible, general approach to the formation of a wide range of new nanoporous metals not currently accessible by state-of-the-art nanoscience. Possible applications abound, not only in catalysis, fuel cells, and ICF, but also in applications ranging from hydrogen storage to electron field emission. Because the pore sizes, densities, and surface areas diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_17_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_17_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2c4ee8c490fbbaa5bd88bfa6b69d23c418c2770e --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_17_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +are dramatically different from those of other metal foams currently being produced, there are sure to be many other interesting discoveries as more applications are investigated. NWJ + +Point of contact: + +Bryce Tappan, 667-0533, btappan@lanl.gov + +Other LANL team members who contributed to this research include David Chavez, Darren Naud, Erik Luther, Michael Hiskey, My Hang Huynh, David Oschwald, and Steven Son. + +This research recently won an R&D Magazine 2005 R&D 100 Award. This award program, which each year recognizes the world's top 100 scientific and technological advances, is designed to honor significant commercial promise in products, materials, or processes developed by the international research and development community. + +What are transition metals? + +The elements in the periodic table are often divided into four categories: main group elements, transition metals, lanthanides, and actinides. The main group elements include the active metals in the two columns on the extreme left of the table and the metals, semimetals (metalloids), and nonmetals in the six columns on the far right. + +The transition metals, or transition elements, are the metallic elements in the columns in the center of the table, forming a bridge or transition between the active metals on the left and the elements on the right. + +Lanthanides and actinides are usually shown in two rows below the main table; they are sometimes called the inner transition metals because their atomic numbers fall between the first and second elements in the last two rows of the transition metals (after lanthanum and actinium, respectively). + +Periodic Table of the Elements + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_19_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_19_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f7f31e00f8cf8b7f925bea3eb57037a4f05c6c3e --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_19_pg1_pg1_repeat1.md @@ -0,0 +1,88 @@ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
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£ £ ä £ ä™ £ än £ äÇ £ äÈ £ äx £ ä{ £ äÎ £ äÓ œ > ` ˆ ˜ } ʜ VŽ Ónx½ ÊqÊä» This diagram shows the layout of building 340 and its nine bays (rooms 102–11 0). The inset shows an adjacent bay and an abutting bay.
+ +Joint Characterization, Analysis, and Testing conducted at the TA-16-340 complex (JCAT-340). + +The objectives for the HE safety tests were to execute full-scale testing to + +- qualify safety engineering controls used to mitigate a blast, + +- validate HE facility design criteria, and + +- validate tools used to quantify the safety margin in the DOE authorization basis. + +The JCAT-340 Project consisted of 17 detonation experiments that used 0.03–300 lb of PBX 9501 within the processing bays of buildings 340 and + +342. Detonation experiments at various heights and locations assessed the dynamic response of the Laboratory’s HE operations buildings. The test sequence was designed to increase understanding of the potential operational safety hazards and associated physics of internal explosions, focusing on the blowout walls’ and buildings’ structural response. + +- Blowout wall response—The 3-in.-thick blowout walls consisted of two aluminum sheets that encased insulation. Interlocking panels of this material formed the blowout walls, which were designed to protect the interior of the building + +from the weather, but dislodged at an applied load of approximately 1.5 psi to rapidly dissipate an explosion away from the building and its occupants. The JCAT-340 test series studied the dislodging characteristics of the blowout walls and effects of the wraparound pressure on an abutting bay. In addition, a test was conducted to reduce wraparound effects by implementing a wedge deflector to mitigate wraparound pressures. This wedge was designed to reflect the initial pressures at the end of the bay wall back into the explosives bay, thereby reducing the pressure that turns the corner and affects the abutting bays. + +- Structural response—This test series was designed to characterize the structures’ dynamic response (spallation, cracking, displacement, etc.) to overpressure generated by detonating HE. Buildings 340 and 342 were constructed in the early 1950s with 2-ft-thick, highly reinforced concrete walls that contained a vast web of rebar, roughly 3.5% by volume. Structural models will be calibrated from the results of a series of 5-lb test shots; larger charges were detonated to examine various structural effects. + +Large hydrodynamic computational models provided the data to set the ranges on the instruments for the pressure we expected to measure during diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_20_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_20_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3c72fe7093a8c511310a17a6674454194630bbbd --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_20_pg1_pg1_repeat1.md @@ -0,0 +1,33 @@ +A wedge deflector (shown at the end of the building) was used to mitigate wraparound effects in one test. + +![](figure) + +![](figure) + +the tests and to assess the buildings’ structural response. The hydrocodes CTH, a Sandia National Laboratories code, and AUTODYN, a commercial code, provided the basis for modeling. + +An array of incident and reflective pressure transducers placed on the interior and exterior of buildings 340 and 342 gathered pressure data. Accelerometers, pretest and posttest forensics, and high-speed cameras captured blowout wall and structural response data. Standard and digital videos recorded detonations and provided a real-time view of ongoing events. Additionally, noise, dust, and gas meters and x-ray element analyzers assessed the industrial hygienic state of the buildings after each detonation. + +![](figure) + +![](figure) + +After HE pipes, fixtures, and asbestos were removed, instrumentation was attached to the exterior and interior of building 340 before a test. + +![](figure) + +![](figure) + +After a 25-lb test shot, blowout panels are on the ground and blowout panels in the abutting bay are damaged. + +Preliminary results of the tests show five important findings. + +1. The blowout walls worked as designed; they dislodged and the pressure rapidly vented from the bays. + +2. Experiments in which a blowout wall was present produced significantly higher pressures and had greater structural impact from the initial shock wave reflected off the panels than did experiments without a blowout wall. + +![](figure) + +![](figure) + +Blowout panels and other debris are scattered up to 300 ft away from building 340 after a 25-lb test shot. diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_22_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_22_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..43ddc489fccab3271d7d6ac36ea35826f60d3b46 --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_22_pg1_pg1_repeat1.md @@ -0,0 +1,41 @@ +# Successful Hydrotests Completed at DARHT + +Dynamic Experimentation (DX) Division scientists at the Dual-Axis Radiographic Hydrodynamic Test (DARHT) Facility successfully completed two essential hydrotests in 2005. Hydroshots 3625 and 3612 were part of a test series designed to gather data on the LANL-developed W76 warhead, which is carried on Trident submarine-launched ballistic missiles. + +![](figure) + +![](figure) + +Containment foam. Before the tests, technicians filled a tent-like structure with an aqueous foam to limit dispersal of materials such as beryllium, depleted uranium, and lead into the environment. Although hydrotest 3625 was a gas cavity test and hydrotest 3612 was a JOPIN test, they used similar foam containment systems to avoid contaminating the environment. + +tests at DARHT include 3596 (in 2004 for the W76 Mod 0 LEP) and 3612 (in 2005 for the W76 Mod 1 LEP). + +Gas cavity hydrotests + +- have a small field of view, + +- require a compact setup geometry, + +- can “see through” very opaque object features that are difficult to radiograph, and + +Hydrotest 3625 was conducted April 1, 2005, and hydrotest 3612 was conducted 3 months later on July 1, 2005. Results from these two hydrotests allow researchers to compare data with hydrocode predictions that eventually will be factored into refurbishment requirements for final certification of NNSA’s W76 Mod 1 Life Extension Program (LEP). graphic intensity of DARHT, + +DARHT is a LANL high-explosives (HE) firing site that has hydrodynamic experiment capabilities; i.e., measurements are made at the extreme temperatures and pressures generated by the detonating HE, wherein the tested metals flow like fluids. Scientists use DARHT’s flash x-ray machine and cameras to study the implosion characteristics—recording interior images during implosion—of nonnuclear mock-ups of nuclear weapon components. + +Hydrotests fall into one of two categories: joint radiograph and implosion pin (JOPIN) tests and gas cavity tests. Although DARHT can accommodate both types of hydrotests, it is the world’s most capable gas-cavity test facility. LANL has conducted numerous gas cavity tests, including 3605 and 3623 (in 2004 for the W76 Mod 0 LEP) and 3625 (in 2005 for the W76 Mod 1 LEP). Recent JOPIN + +- use the gamma-ray camera (GRC) as a principal diagnostic tool. + +JOPIN shots, which do not require the full radio- + +- have a very large field of view, + +- can “see through” transparent object features that are easily radiographed, + +- are concerned with case and other device components, + +- diagnose early-time implosion with pins, and + +- use many different diagnostics. + +The manufacture of some W76 replacement components, scheduled to begin in late 2006, will be based in part on the results of the DARHT W76 test series. Before manufacturing begins, LANL will conduct confirmatory experiments to ensure that the new components perform as well as those built diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_32_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_32_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d7aae3cbd70f27787502fc16e7c66044990e7269 --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_32_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +LD-102, the second implosion physics experiment in the LD series, was conducted on schedule, 2 weeks after LD-101. LD-102 had two objectives: (1) to demonstrate that Atlas can conduct physics experiments at 2-week intervals and (2) to continue the investigation of instability physics in imploding liner systems, specifically by changing the drive conditions to explore perturbation growth. + +The diagnostic suite for LD-102 was similar to that for LD-101. All critical diagnostics delivered good data. LD-102 explored liner performance at lower current delivery (more-gentle drive) than LD-101. Under reduced drive, enhanced instability might (by some models) have been expected. However, radiographs showed no evidence of increased instability at the lower drive achieved in LD-102 in agreement with previous Atlas experiments at LANL. + +Throughout the LD series, shot operations became smoother and more efficient, indicating that the Atlas system was successfully relocated and that the new BN operating team was rapidly gaining experience with the pulsed-power operating environ- + +Expanded return conductor + +Liner on impact + +Target + +“Momentum” traps ment. Preparation for the next experiments (Spall) required some minor changes in machine configuration, installation of the spall target assembly, and some additional diagnostics, which made the prompt execution of the first Spall test another notable accomplishment. + +Two material damage experiments, Spall 101 and Spall 102, were conducted on August 25 and September 8, additionally demonstrating that the Los Alamos-BN team can set up and conduct implosion liner experiments on a 2-week schedule. + +The Spall test series is designed to provide detailed information about the formation and evolution of damage in a well-characterized reference material (aluminum) using the converging geometry characteristic of the operation of a nuclear weapon. Spall experiments on Atlas at NTS continue the experimental series begun in 2002 when Atlas was located at Los Alamos. After benchmarking the results of the NTS Spall experiments against data collected using the same techniques and parameters in Los Alamos, the series will explore recollection and + +Undamaged material + +Spallation void + +Spalled layer + +![](figure) + +Samples recovered after Atlas experiments allow post-shot metallurgy to explore structure of material after it has been strained (deformed) beyond failure. Both spall layer and undamaged material show residual evidence of significant distention and void formation prior to failure instead of a clean, sharp break. + +![](figure) diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_38_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_38_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5772a383aefa301badc35ad4bd334bdc7546924b --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_38_pg1_pg1_repeat1.md @@ -0,0 +1,47 @@ +,ii>Ãi œ vÊÌi ˜ à ˆ œ ˜ + +>ÃiÀÊ`ÀˆÛi + +,> Àiv> V̈œ ˜ à + +-  > à ̈ VÊà œ VŽ + +ÊÊÊ + + > à ̈ VÊÜ> Ûi + +/ i ˜ à ˆ œ ˜ + +![](figure) + +| | ä°x | >Ã̈V | | | | | | +| --- | --- | --- | --- | --- | --- | --- | --- | +| /> À} iÌ | | | | | | | | +| * œÃˆÌˆœ˜ | ä | | | | | | | +| | £ | Ó Î | { | x | È | Ç | n | + +Position-time diagram of waves induced by laser ablation. Note the elastic precursor running ahead of the initial plastic shock. Information on the flow stress can be derived from the velocity history of the surface as the elastic and plastic waves appear. + +for compressed states because the c/a predictions included no data for the STP state. + +To predict the elastic constants, we made similar quantum mechanical calculations as the crystal was distorted (strained) by compression along different crystal directions and by shearing different pairs of faces. In each case, we used the electron states to calculate stress on the crystal; the elastic constants are the rates with which stress changes with strain. We repeated the calculations for several different compressions, giving the elastic constants as functions of compression. Again, the values we predicted for STP agreed reasonably well with the measured values, giving us confidence that our predicted variation with compression is also reasonable. + +# Measuring Crystal Properties + +The rate of plastic flow, which is related to the elastic strain or stress that the material can support before flow occurs (also called the yield stress), depends greatly on the time available for crystal defects to move—and therefore on the thickness of the component. + +We used LANL’s Trident laser to induce shock waves in beryllium crystals 40- to \(100-\mu\mathrm{m}\) thick— similar to the \(150-\mu\mathrm{m}\) thickness of the ignition capsule—and studied the shape of elastic waves that run ahead of the shock. From these waves, we inferred parameters in a plasticity model that represents the properties of the defects accurately. + +£ °x + +£ flÝ« i À ˆ “ i ˜ Ì ‡ * ]Êä°ÎÎÊˇ* > ‡ * ]ʙ °äÊˇ* > * , ]Êà « >   + +*>Ã̈V + +\(/ˆ“iÊ\Delta vÌiÀÊ-Ì>\) ÀÌʜ vÊÆ> ÃiÀÊ* ՏÃiÊ­˜ î + +Velocity history from the free surface of a beryllium crystal, compared with simulations using different models of plasticity. Elastic-plastic (E-P) simulations are the simplest models of plasticity; 0.33 GPa is a typical flow stress on microsecond time scales. The elastic wave breaks out at the correct time, but the amplitude is too low and the shape of the plastic wave is incorrect. Increasing the flow stress to 9 GPa improves the amplitude but not the shape. The plastic relaxation (PR) model reproduces the shape of the elastic wave more accurately; this model did not include work hardening, so the rising part of the elastic wave shows stronger reverberations in the simulation than we observed experimentally. The PR simulation also included spall, improving the match after the peak of the plastic wave. Note that more accurate simulations of the elastic wave also improve the match in the plastic region. + +For a range of drive pressures, the elastic wave outruns the shock. Wave amplitude is set by yield stress and its precise shape gives more details that constrain parameters in the plasticity model. Plastic flow occurs as defects—dislocations and twin boundaries—move along planes in the lattice of atoms (the slip systems) that comprise the crystal. The average speed of a defect’s movement across a plane depends on the elastic shear stress resolved over that plane; generally, several different slip systems may be active simultaneously as a crystal deforms. The stress required to activate slip systems may vary, as may the population of defects able to mediate strain in each slip system. Our studies included these variations with experiments on beryllium crystals of different orientations. + +Having developed a plasticity model for single beryllium crystals, we can predict the response of a given microstructure to loading and heating. Because it is crucial to test the predictions, we will obtain elastic- diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_47_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_47_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..52c93da0d32a4bc308a3726238ebc81c90c1aeb7 --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_47_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +# A backward glance + +![](figure) + +# Eyewitnesses to Trinity + +July 16, 2005, marked the 60th anniversary of the world’s first nuclear explosion. Conducted at the Trinity Test Site near Alamogordo, New Mexico, the test was needed to determine if a radical new weapon, nicknamed “the gadget,” would work. Its designers were confident that their calculations were correct although they could not pinpoint how large or powerful the detonation would be. + +At base camp 10 miles from ground zero, Enrico Fermi protected his face “by a large board in which a piece of dark welding glass had been inserted.” His first impression of the explosion was “the very intense flash of light” that seemed “brighter . . . than in full daylight.” Through the glass, he saw “a conglomeration of flames that promptly started rising,” becoming “a huge pillar of smoke with an expanded head like a gigantic mushroom that rose rapidly beyond the clouds.” About 40 seconds after the explosion, the air blast reached him. He estimated its strength by “dropping from about six feet small pieces of paper before, during and after the passage of the blast wave,” concluding that it corresponded “to the blast that would be produced by ten thousand tons of T.N.T. [sic]” The actual yield was about 21 kt. + +Victor Weisskopf, also at base camp “on a little ridge about 100 yds. [sic] east of the water tower,” watched indirectly “through the dark glass” so he could see the deflected light. “When the explosion went off,” he wrote, “I was first dazzled by this indirect light which was much stronger than I anticipated, and I was not able to concentrate upon the view through the dark glass.” Looking directly at the explosion 3 seconds later, he saw “a reddish glowing smoke ball rising with a thick stem of dark brown color . . . surrounded by a blue glow.” The shock wave through the clouds was “plainly visible as an expanding circle all over the sky where it was covered by clouds.” Weisskopf “felt very strongly the heat radiation all over the exposed parts of my body.” The sound wave arrived “after about 45 seconds and it struck me as being much weaker than anticipated,” he wrote. + +About 20 miles from the detonation point, Captain R. A. Larkin, seated on the ground, deliberately had his “eyes fixed on the ground immediately in front + +. . . to avoid the blinding flash” he expected. “My first impression,” he said, “was of a sudden brilliant lighting of the surrounding landscape, accompanied by a momentary flash of heat.” He was surprised that the illumination, “initially quite brilliant, continued to increase for a brief interval.” His dark glass filter was “designed to eliminate over 99% of the light.” But when he looked through it, he was momentarily blinded, much as he would have been by a “close flash of lightning on a dark night.” He noted a “ball of light” and below it “a column of red flame about 150 or 200 yards in diameter. Flickering red reflections were distinctly seen on the clouds above the ball of light.” + +“At about ten seconds after detonation . . . the ball and column took on the shape of a vast mushroom.” Ten minutes after detonation the cloud was still “quite distinct and rising rapidly.” Fifteen minutes later, the pillar under the cloud had faded, and after 30 minutes the cloud “faded from view.” + +At Military Police Post No. 2 (20 miles from “zero point”), Ralph Carlisle Smith “stretched out on a blanket facing south” and looked through a welder’s glass with his left eye. The flash temporarily blinded his open, unprotected right eye but through his left he saw the “amazingly bright” light that “turned yellow, then red, and then beautiful purple,” eventually rising “in something of a toadstool effect.” After the cloud turned to a “ponderously” moving cylinder of white smoke and a “hole was punched well above the white smoke column,” he saw “two fog rings . . . well above the white smoke column.” Then, he said, “There was a spontaneous cheer of the observers.” Although he did not report heat, Smith noted that roughly 1.5 minutes after the light “a sharp loud crack swept over us—it reverberated through the mountain[s] like thunder.” He estimated the fireball was “1 to 2 miles wide.” A nearby observer guessed the strength to be “at least 5000 tons and probably a lot more.” + +7 + +For these and the accounts of other observers in the Trinity test area, see the Laboratory’s history page at http://www.lanl.gov/history/atomicbomb/trinity. shtml. diff --git a/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9f17f185fa7b220c1d43b5c3e543d31226fea9e6 --- /dev/null +++ b/outputs/multi_column/081875a1035e34dee439b9a2a3a55e319405_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,33 @@ +# A New Look at Trinitite + +Sixty years after the July 16, 1945, test of the first nuclear bomb (originally called an atomic bomb) at Trinity Site on White Sands Missile Range (WSMR) in New Mexico, we collected many samples of the soil fused by the explosion. This very slightly radioactive green glass is called trinitite. + +(c) + +(a) + +(b) + +![](figure) + +![](figure) + +Three views of trinitite samples: (a), the top (blast side); (b), the bottom (ground side); (c), a side view showing the bubble voids (vesicles). + +Our purposes were to use the properties of trinitite to calculate backward to the yield, fireball temperature, fireball duration, heat in the rising fireball, and the spread of ejecta from the Trinity test and to suggest that trinitite was deposited by a rain of molten droplets and puddling from the heat. Using our trinitite samples, we calculated some probable conditions of the nuclear explosion. We estimate the yield of the Trinity event was 9–18 kt, plus approximately 4.2 kt from the energy carried away by the mushroom cloud. We calculated an average fireball temperature of 8430 K, the duration of heating at approximately 3.1 s, and a crater depth of approximately 4 ft. These numbers compare reasonably well with the real-time measurements calculated 60 years ago and with unclassified published data. + +If Trinity Site had not been cleaned up (bulldozed) by removing and/or burying a significant portion of the trinitite, a field survey would provide the numbers needed for our calculations. Because an explosion of plutonium formed the trinitite, most previous observations had a radiological emphasis. + +Our discussion is confined to macroscopic measurements and theoretical calculations of the blast based on a few assumptions. We show how observations of nonradiological trinitite properties and relatively straightforward calculations provide estimates of the event that produced the “lake of green glass” in 1945. + +### Yield Calculation + +Most of our samples are approximately the size of a small pancake with similar thicknesses that include significant trapped bubble voids. The top (blast side) is smooth with a light green glassy luster. The bottom (ground side) is rough and light tan with sandy inclusions. Comparing our samples with an old photo, we conclude they are a reasonable representation of the glassy trinitite field. The average thickness of our samples is 1–2 cm; samples <1 cm or >2 cm in thickness are less common. Determining the thickness of the trinitite layer was critical in our yield calculation. + +Another crucial number is the maximum radial extent R of the trinitite layer (thickness \(\Delta L)\) from ground zero. We used aerial photos taken 28 h after the Trinity event to determine the radial extent. These photos show the trinitite layer extended to a radius of at least 300 m. We used a value of R = 300 m for the radial extent of the trinitite. + +![](figure) + +Undisturbed surface of the trinitite field. + +![](figure) diff --git a/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_12_pg1_pg1_repeat1.md b/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_12_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ca543408837bf27f94d90a8d95ac266a696421ec --- /dev/null +++ b/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_12_pg1_pg1_repeat1.md @@ -0,0 +1,11 @@ +![](figure) + +Fig. 10. Fission-track constraints on the time of commencement of cooling for all AFTA samples in this study for which there is clear evidence for paleo-heating (time constraints are also summarized in Table 3 for each sample). Results show strong and consistent evidence for two widespread events in which cooling commenced between 100 and 90 Ma, and sometime in the last 20 Ma; some solutions fall off the main trend, permitting to presume an intermediate event between 65 and 50 Ma. Note this conclusion is based on the simple assumption that the events occurred synchronously across the study area, as illustrated by the interpreted overlap in the timing of events. Important, as illustrated above, considerably more intra-plateau complexity would be allowed in the Borborema region if the assumption of synchronicity was not imposed. + +ii. Other less dominating, intermediate event of Paleogene– Eocene age is recorded in the region (samples RD57-17, -21, -29, -31), as well as the possibility of an older event is suggested by the sample RD57-23. + +iii. It is not clear whether the main events can be represented as a single long-term cycle of continuous cooling, or if they represent discrete episodes of heating/cooling, in which basement was uplifted to or near the surface during the interval between the two events. If the recognized events are caused by paleo-burial, followed by erosion, the results demand kilometer-scale uplift and denudation of the crystalline basement, in the order of 1000–3000 m, since the mid Cretaceous breakup. Obviously, the estimate of erosion relies heavily on the assumed paleogeothermal gradient (and hence is associated with significant uncertainty, as different blocks may have been submitted to distinct thermal evolutions). + +## 6. Significance of the fission-track results + +Over the past few years there have been a number of fission-track studies from eastern Brazil (Gallagher et al., 1994; Karner et al., 1994; Hegarty et al., 1996; Harman et al., 1998; Hackspacher et al., 2004), none of which can be easily linked to topography generation and a causative tectonic event. For example, Harman et al. (1998) in their study of the Guaporé and São Francisco cratons show fission-track ages that range from 309–137 Ma to 260–76 Ma, respectively. They suggest that their fission-track results demonstrate two main pulses of denudational cooling: (1) the first beginning at w130 Ma, and (2) a younger episode of denudational cooling that began in the Late Cretaceous (w80–60 Ma). While the authors attempt to relate the first event with the initial stages of breakup, our results indicate that fission-track age resetting is occurring uniformly over a vast geographic region, 200–400 km away from the sites of rifting. Harman et al. (1998) have invoked shear zone reactivation, synchronous with the Santonian events of central Africa, as a possible mechanism controlling their 80–60 Ma event (Late Cretaceous). It is extremely unlikely that localized shear zone reactivation can generate broadly distributed and relatively high (100s of meters) topographic relief across northeastern Brazil on a different plate than the observed Santonian inversion of central Africa (Guiraud and Bosworth, 1997). The studies of both Gallagher et al. (1994) and Karner et al. (1994) show fission-track ages increasing with elevation towards the continental interior. This type of age profile is considered a ‘‘classic’’ response of rift flank denudation driven by slope retreat processes in which younger fission-track ages are at the base of the eroding escarpment and the older ages, reflecting minimal erosion/ cooling, are towards the crescent of the escarpment. The fission-track data in this study do not show this trend. In the Borborema Province, our derived thermal history solutions are somewhat similar across the entire study area, irrespective of rock type, stratigraphic age and elevation. We believe this response is best accounted for by regional denudation, but a component of higher heat flow cannot be ruled out, as various paleothermal events derived from fission-track analysis on the conjugate African margin (Bray et al., 2002) were in part controlled by elevated heat flow during the mid Cretaceous. An active rift model, which in effect is a combination of plume dynamics with lithosphere extension, has long been hypothesized to drive the onset of rifting in northeastern Brazil (O’Connor and Duncan, 1990; Wilson, 1992; Lima Neto, 1998a; Thomaz Filho et al., 2000). Intracontinental rifting occurred in northeastern Brazil (e.g. the Rio do Peixe, Araripe and Iguatu Basins) between 140 and 118 Ma, and the amount of extension responsible for these interior basins was localized and minor (b = 1.1–1.2; e.g. Magnavita et al., 1994). The minor extension led a number of authors to argue against the role of mantle plumes in triggering Early Cretaceous extension (e.g., Matos, 2000, 2001; Fairhead and Wilson, 2005). However, the broad zone of diffuse 145–125 Ma tholeiitic volcanism onshore (and younger volcanism offshore) northeastern Brazil, together with the restricted Late Albian volcanism in the Pernambuco–Paraı´ba Basin, requires a significant thermal anomaly within and large partial melting of the asthenosphere or mantle lithosphere. Recently, Kusznir and Karner (2007) proposed that continental lithosphere thinning leading to breakup is controlled by an upwelling, divergent flow field that depending on the ascent velocity versus the divergent velocity, preferentially thins the lower continental crust and lithospheric mantle during extension. The diff --git a/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_16_pg1_pg1_repeat1.md b/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_16_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b8633b9bf660ff8ce8e166b07403925d903e2066 --- /dev/null +++ b/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_16_pg1_pg1_repeat1.md @@ -0,0 +1,101 @@ +Cremonini, O.A., 1996. Evolução tectônica da área de Ubarana, porção submersa da Bacia Potiguar. Boletim de Geociências da Petrobras 9 (1/4), 81–98. + +Cremonini, O.A., Karner, G.D., 1995. Soerguimento termal e erosão na Bacia Potiguar submersa, e seu relacionamento com a evolução da margem equatorial brasileira. In: XVI Simpósio de Geologia do Nordeste, Recife, Boletim 14, pp. 181–184. + +Cremonini, O.A., Goulart, J.P.M., Soares, U.M., 1998. Tectono-stratigraphic evolution of offshore Potiguar Basin, Brazil. In: AAPG International Conference and Exhibition, Rio de Janeiro, Extended Abstract Volume, pp. 44–45. + +Dantas, E.L., Hackspacher, P.C., Schmus, W.R.V., Neves, B.B.B., 1998. Archean accretion in the São José do Campestre Massif, Borborema province, northeast Brazil. Revista Brasileira de Geociências 28 (2), 221–229. + +Davis, M., Kusznir, N.J., 2004. Depth-dependent lithospheric stretching at rifted continental margins. In: Karner, G.D., Taylor, B., Driscoll, N.W., Kohlstedt, D.L. (Eds.), Rheology and Deformation of the Lithosphere at Continental Margins. Columbia University Press, New York, pp. 92–136. + +Destro, N., Szatmari, P., Ladeira, E.A., 1994. Post-Devonian transpressional reactivation of a Proterozoic Ductile Shear Zone in Ceará, NE Brazil. Journal of Structural Geology 16 (1), 35–45. + +Duddy, I.R., Green, P.F., Laslett, G.M., 1988. Thermal annealing of fission tracks in apatite – 3. Variable temperature behaviour. Chemical Geology (Isotope Geoscience Section) 73, 25–38. + +Ernesto, M., 2005. Paleomagnetism of the post-paleozoic alkaline magmatism in the Brazilian Platform: questioning the mantle plume model. In: Comin-Chiaramonti, P., Gomes, C.B. (Eds.), Mesozoic to Cenozoic Alkaline Magmatism in the Brazilian Platform. EDUSP/FAPESP, São Paulo, pp. 689–705. + +Fairhead, J.D., Wilson, M., 2005. Plate tectonic processes in the South Atlantic Ocean: do we need deep mantle plumes? In: Foulger, G.R., Natland, J.H., Pressnall, D.C., Anderson, D.L. (Eds.), Plates, Plumes and Paradigms. Special Paper 388. Geological Society of America, pp. 537–553. + +Feijó, F.J., 1996. O inıćio da livre circulação das águas do Oceano Atlântico. Boletim de Geociências da Petrobras 9 (1/4), 157–164. + +Fleischer, R.L., Price, P.B., Walker, R.M., 1975. Nuclear Tracks in Solids-Principles and Applications. University of California Press, Berkeley, 605 pp. + +Gallagher, K., Hawkesworth, C.J., Mantovani, M.S.M., 1994. The denudation history of the onshore continental margin of the SE Brazil inferred from apatite fission track data. Journal of Geophysical Research 99 (B9), 18117–18145. + +Gallagher, K., Brown, R., Johnson, C., 1998. Fission track analysis and its application to geolgical problems. Annual Review of Earth and Planetary Sciences 26, 519–572. + +Gil, J.A., 1996. Estratigrafia e análise paleoambiental da plataforma carbonática Jandaıŕa; turoniano-campaniano da porção centro-oeste da Bacia Potiguar. Unpublished Master Thesis, UFRGS, Porto Alegre, 146 pp. + +Gleadow, A.J.W., Duddy, I.R., Lovering, J.F., 1983. Fission track analysis: a new tool for the evaluation of thermal histories and hidrocarbon potential. The Australian Petroleum Exploration Association Journal 23, 93–102. + +Gleadow, A.J.W., Duddy, I.R., Green, P.F., Lovering, J.F., 1986. Confined fission track lengths in apatite – a diagnostic tool for thermal history analysis. Contributions to Mineralogy and Petrology 94, 405–415. + +Gleadow, A.J.W., Kohn, B.P., Brown, R.W., O’Sullivan, P.B., Raza, A., 2002. Fission track thermotectonic imaging of the Australian continent. Tectonophysics 349 (1–4), 5–21. + +Green, P.F., Duddy, I.R., Gleadow, A.J.W., Tingate, P.T., Laslett, G.M., 1986. Thermal annealing of fission tracks in apatite 1-A qualitative description. Chemical Geology 59, 237–253. + +Green, P.F., Duddy, I.R., Gleadow, A.J.W., Lovering, J.F., 1989a. Apatite fission track analysis as a palaeotemperature indicator for hydrocarbon exploration. In: Naeser, N.D., McCulloh, T.W. (Eds.), Thermal history of sedimentary basins – methods and case histories. Springer-Verlag, New York, pp. 181–195. + +Green, P.F., Duddy, I.R., Laslett, G.M., Hegarty, K.A., Gleadow, A.J.W., Lovering, J.F., 1989b. Thermal annealing of fission tracks in apatite 4-quantitative modeling techniques and extension to geological timescales. Chemical Geology 79 (2), 155–182. + +Green, P.F., Hegarty, K.A., Duddy, I.R., 1996. Compositional influences on fission track annealing in apatite and improvement in routine application of AFTA. In: AAPG Meeting, San Diego, Annual Meeting Abstracts, vol. 5. AAPG/SEPM. A.56. + +Guiraud, R., Bosworth, W., 1997. Senonian basin inversion and rejuvenation of rifting in Africa and Arabia: synthesis and implications to plate-scale tectonics. Tectonophysics 282 (1–4), 39–82. + +Gunnell, Y., Fleitout, L., 2000. Morphotectonic evolution of the Western Ghats, India. In: Summerfield, M.A. (Ed.), Geomorphology and Global Tectonics. John Wiley & Sons Ltd., Chichester, pp. 320–368. + +Hackspacher, P.C., Ribeiro, L.F.B., Ribeiro, M.C.S., Fetter, A.H., Hadler Neto, J.C.H., Tello, C.E.S., Dantas, E.L., 2004. Consolidation and break-up of the South American platform in southeastern Brazil: tectonothermal and denudation histories. Gondwana Research 7 (1), 91–101. + +Harman, R., Gallagher, K., Brown, R., Razza, A., Bizzi, L., 1998. Accelerated denudation and tectonic/geomorphic reactivation of the cratons of northeastern Brazil during the Late Cretaceous. Journal of Geophysical Research – Solid Earth 103 (11), 27091–27105. + +Hegarty, K.A., Duddy, I.R., Green, P.F., 1996. The thermal history in and around the Paraná Basin using apatite fission track analysis – implications for hydrocarbon occurrences and basin formation. In: Comin-Chiaramonti, P., Gomes, C.B. (Eds.), Alkaline Magmatism in Central-Eastern ParaguayRelationships with coeval magmatism in Brazil. USP, São Paulo, pp. 67–84. + +Hegarty, K.A., Morais Neto, J.M., Karner, G.D., 2002. The enigma of the Araripe Plateau – new constraints on its uplift and tectonic history using AFTA. In: 41 Congresso Brasileiro de Geologia, João Pessoa, Abstracts Volume, p. 495. + +Hegarty, K.A., Morais Neto, J.M., Karner, G.D., 2004. Mapping anomalous topography through time and understanding its origins – a study of the Borborema Province, NE Brazil. In: 32nd International Geological Congress, Florence, Abstracts CD, p. G05.08. + +Issler, D.R., Willett, S.D., Beaumont, C., Donelick, I.A., Grist, A.M., 1999. Paleo-temperature history of two transects across the Western Canada Sedimentary Basin: constraints from apatite fission track analysis. Bulletin of Canadian Petroleum Geology 47 (4), 475–486. + +Jardim de Sá, E.F., 1994. A Faixa Seridó (Provıńcia Borborema, Nordeste do Brasil) e seu significado geodinâmico na Cadeia Brasiliana/Pan-Africana. Unpublished PhD Thesis, Universidade de Brasıĺia, Brasıĺia, 803 pp. + +Jardim de Sá, E.F., Matos, R.M.D., Morais Neto, J.M., Pessoa Neto, O.C., Saadi, A., 1999. Epirogenia cenozóica na Provıńcia Borborema: śıntese e discussão sobre os modelos de deformação associados. In: VII Simpósio Nacional de Estudos Tectônicos – I International Symposium on Tectonics, Lençóis, Annals, pp. S4:58–61. + +Jardim de Sá, E.F., 2001. Tectônica cenozóica na margem equatorial da Provıńcia Borborema, Nordeste do Brasil (A contribuição da Geologia Estrutural no continente). In: VIII Simpósio Nacional de Estudos Tectônicos – II International Symposium on Tectonics, Recife, Annals, pp. 25–28. + +Jardim de Sá, E.F., Vasconcelos, P.M., Kohn, B.P., Matos, R.M.D., Nascimento, M.A.L., Souza, Z.S., 2004. Datações Ar/Ar do magmatismo Ipojuca e a idade do rifteamento na sub-bacia de Pernambuco, Nordeste do Brasil. In: 42 Congresso Brasileiro de Geologia, Araxá, Abstracts CD, p. S32.399. + +Jardim de Sá, E.F., Souza, Z.S., Vasconcelos, P.M., Saadi, A., Galindo, A.C., et al., 2005. Marcos Temporais para a Evolução Cenozóica do Planalto da Borborema. In: X Simpósio Nacional de Estudos Tectônicos – IV International Symposium on Tectonics. SBG, Curitiba, Abstracts CD, pp. 160–162. + +Karner, G.D., Ussami, N., Alkimim, F.F., 1994. Tectonic significance of the topography of southeastern Brazil: speculations and implications. Revista da Escola de Minas 47 (1), 18–19. + +Koutsoukos, E.A.M., 1992. Late Aptian to Maastrichtian Foraminiferal Biogeography and Paleoceanography of the Sergipe Basin, Brazil. Palaeogeography Palaeoclimatology Palaeoecology 92 (3–4), 295–324. + +Kusznir, N.J., Karner, G.D., 2007. Continental lithospheric thinning and breakup in response to upwelling divergent mantle flow: application to the Woodlark, Newfoundland and Iberia margins. In: Karner, G.D., Manatschal, G., Pinheiro, L. (Eds.), Imaging, mapping and modeling continental lithosphere extension and breakup. Special Publication 282. Geological Society, London, pp. 389–419. + +Lana, M.C., 1990. Bacia de Sergipe-Alagoas: uma hipótese de evolução tectonosedimentar. In: Raja Gabaglia, G.P., Milani, E.J. (Eds.), Origem e Evolução de bacias sedimentares. PETROBRAS, Rio de Janeiro, pp. 311–332. + +Laslett, G.M., Green, P.F., Duddy, I.R., Gleadow, A.J.W., 1987. Thermal annealing of fission tracks in apatite – 2. A quantitative analysis. Chemical Geology (Isotope Geoscience Section) 65, 1–13. + +Lim, H.S., Lee, Y.I., Mim, K.D., 2003. Thermal history of the Cretaceous Sindong Grup, Gyeongsang Basin, Korea based on fission track analysis. Basin Research 15, 139–152. + +Lima, M.G., Vasconcelos, P.M., Farley, K.A., Jardim de Sá, E.F., 2007. Datação do intemperismo impõe limites na idade da Formação Barreiras, Bacia Potiguar, nordeste do Brasil. In: XI Conferência da Associação Brasileira de Estudos do Quaternário, Belém, Abstracts CD. + +Lima Filho, M.L., Szatmari, P., 2002. Ar–Ar geochronology of volcanic rocks of the Cabo Magmatic Province (CMP) – Pernambuco Basin. In: II Simpósio sobre vulcanismo e ambientes associados, Belém, Abstracts Volume, p. 59. + +Lima Neto, F.F., 1998a. O exemplo da interferência mecânica de uma interface fraca: o campo atual de tensões na Bacia Potiguar. Unpublished Master Thesis, Universidade Federal de Ouro Preto, Ouro Preto, 320 pp. + +Lima Neto, F.F., 1998b. Evolução pós-paleozóica do nordeste brasileiro: ‘‘hot spots’’ em manto frio. In: 40 Congresso Brasileiro de Geologia, Belo Horizonte, Abstract Volume, p. 103. + +Long, L.E., Sial, A.N., Nekvasil, H., Borba, G.S., 1986. Origin of Granite at Cabo De Santo Agostinho, Northeast Brazil. Contributions to Mineralogy and Petrology 92 (3), 341–350. + +Mabesoone, J.M., Campos e Silva, A., Beurlen, K., 1972. Estratigrafia e origem do Grupo Barreiras em Pernambuco, Paraı´ba e Rio Grande do Norte. Revista Brasileira de Geociências 2 (3), 173–188. + +Magnavita, L.P., Davison, I., Kusznir, N.J., 1994. Rifting, erosion, and uplift history of the Reconcavo–Tucano–Jatoba rift, northeast Brazil. Tectonics 13 (2), 367–388. + +Matos, R.M.D., 1992. The northeast Brazilian rift system. Tectonics 11 (4), 766–791. Matos, R.M.D., 1999. History of the northeast Brazilian rift system: kinematic implications for the break-up between Brazil and West Africa. In: Cameron, N.R., Bate, R.H., Clure, V.S. (Eds.), The Oil and Gas Habitats of the South Atlantic. Special Publication 153. Geological Society, London, pp. 55–73. + +Matos, R.M.D., 2000. Tectonic evolution of the Equatorial South Atlantic. In: Mohriak, W., Talwani, M. (Eds.), Atlantic rifts and continental margins. Geophysical Monograph 115. Geological Society/AGU, pp. 331–354. + +Matos, R.M.D., 2001. Mantle-plume-generated triple junction between NE Brazil and West Africa? In: 7th International Congress of the Brazilian Geophysical Society. Salvador, Abstracts Volume, pp. 45–48. + +Menezes, M.R.F., Morais Neto, J.M., Szatmari, P. and York, D., 2003. Relações cronológicas entre o vulcanismo Macau e a Formação Serra do Martins, com base diff --git a/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c89b300eb7123fe73c50020948e917d5184a569a --- /dev/null +++ b/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,9 @@ +sand content and maturity of turbidite deposits. Such predictions require information about the history of topography generation, modification, and denudation. Continental landscapes are constantly in a state of flux as drainage systems evolve and interact via the process of river capture during the denudation of topography. In turn, any post-rift tectonics that modifies or generates topography will play a major role in this landscape evolution process, controlling the transport and delivery of clastics by fluvial systems to the margins. Rivers represent point sources of clastics along margins, however, their distribution, energy, and sediment content are prime functions of topography generation and distribution. Once deposition takes place, marine processes such as alongshore drift rework and redistribute the sediments along the margin. During eustatic falls, margins associated with relatively large fluvial systems will tend to be associated with significant drainage rejuvenation, river incision of the exposed shelf, canyon development, and given suitable conditions, the deposition of turbidities. A corollary of this study is to provide suggestions about when clastics from the eroding Borborema topography, as modified by the development and interaction of intracontinental drainage systems, should be delivered to the northern and northeastern Brazilian basins. While this is a local study of the Borborema Province of northeastern Brazil, the implications of this work have far reaching consequences for the stratigraphy of rifted continental margins through the development of hinterland topography. + +## 2. Geological setting + +The Precambrian Borborema Province in northeastern Brazil (Fig. 1) consists of a gigantic fan-like system of right-lateral strike-slip shear zones, juxtaposing Archean to Mesoproterozoic crystalline massifs against belts of Neoproterozoic metasediments (Van Schmus et al., 1998; Dantas et al., 1998). The Borborema strike-slip system corresponds to the west-central portion of the Pan-African/ Brasiliano orogenic collage formed during the Neoproterozoic assembly of West Gondwana (600–580 Ma). The main shear zones of the system, namely the Pernambuco, Patos, Portalegre, Picuı´-João Câmara, Santa Mônica, Remıǵio-Pocinhos and Senador Pompeu shear systems, show orientations varying between E–W and NE–SW (Fig. 1). These structures seem to accommodate large strains in a context of continental collisions involving lithospheric segments of distinct rheological properties; in such continental collisions, rheological competent blocks act as indentors that generate strong shear zone systems as the rheological weaker blocks are squeezed out or ‘‘escape’’ laterally (Jardim de Sá, 1994; Vauchez et al., 1995; Brito Neves et al., 2000). The fragmentation of Gondwana in the Mesozoic is recorded in northeastern Brazil by a series of tectonic and magmatic events, including the development of basins in the continent interior and the Atlantic passive margin. The WNW–ESE and N–S trending segments of the Brazilian continental margin are commonly referred to as Equatorial and Eastern margins, respectively (Fig. 1). These segments, which meet in the region northeast of the Borborema Province, experienced distinct tectonic histories, reflecting two distinct tectonic regimes. The Equatorial segment corresponds to a transform margin, whereas the Eastern segment evolved as a classical divergent, ‘‘passive’’ margin (Matos, 1999). The structuring of the Eastern and Equatorial Margins started with intense crustal stretching during the Mesozoic, which led to the formation of three main Neocomian rift systems in northeastern Brazil: Recôncavo–Tucano–Jatobá and Sergipe-Alagoas, as well as the basins along the Cariri–Potiguar Trend (Figs. 1 and 3). The geometry of these basins was controlled and compartmentalized by the complex network of Proterozoic shear zones. The Cariri–Potiguar Trend (Matos, 1992) is formed by several intracontinental rift basins along a NE–SW axis in the northwestern vicinity of the Borborema Plateau. This trend encompasses small Neocomian (140–118 Ma) basins such as the Rio do Peixe, Iguatu and Icó, and the sub-surface rift sections of the Araripe and Potiguar Basins (Fig. 1), which were aborted during the Barremian in favor of eventual crustal breaching and ocean crust generation to the north and east. The Sergipe-Alagoas Basin on the Eastern continental margin (Fig. 1) is composed of a series of half-graben bounded by N–S, NW- and NE-trending faults (Lana, 1990), also formed during the Neocomian and contains a complete record of both syn-rift and post-rift sediments. Pre-rift sediments include Paleozoic and Jurassic intracratonic sediments. The Recôncavo–Tucano–Jatobá rift system (Fig. 1), also formed during the Neocomian, extends to 400 km in N–S direction in the region south of the Borborema Province (Fig. 1). This system consists of asymmetric grabens separated by basement highs and accommodation zones (Magnavita et al., 1994). + +## 3. Continental rifting and breakup + +In the northeastern portion of the Borborema Province, the breakup of Western Gondwana was preceded by the outpouring of the Rio Ceará-Mirim tholeiites from the late Jurassic to Barremian (145–125 Ma; Fig. 1). South of the Potiguar Basin, this magmatism is represented by an extensive E–W-trending dike swarm (Figs. 1 and 4). O’Connor and Duncan (1990), Wilson (1992), Lima Neto (1998b) and Oliveira (1998), for instance, argued that this igneous activity was mantle plume induced. It was further suggested that these plumes (possibly the Saint Helena and Ascension plumes) might have played an important role in the weakening of the lithosphere and in the extension and breakup of the South American and African plates. As such, the Eastern Brazilian margin represents a volcanic rifted margin, a classification supported by the existence of seaward dipping reflectors within the Sergipe-Alagoas Basin (Mohriak et al., 1998, 2002), and by syn-rift volcanic activity within the Pernambuco–Paraı´ba Basin (Jardim de Sá et al., 2004; Almeida et al., 2005). North of the Potiguar Basin (Fig. 1), continental breakup and seafloor spreading is interpreted to have commenced in the Late Aptian/Early Albian. In the Pernambuco sub-basin (the southernmost portion of the Pernambuco–Paraıba´ Basin; Fig. 1), a late syn-rift magmatic event generated granites and alkali volcanics dated between 105 and 97 Ma (Long et al., 1986; Jardim de Sá et al., 2004). The establishment of open marine conditions between eastern South America and Africa is considered to be of Late Albian age (Koutsoukos, 1992). After continental breakup, the margin underwent lithospheric cooling and subsidence, as recorded in the Potiguar Basin (Fig. 3) by a lower Albian–Campanian transgressive sequence and by an upper Campanian to Recent regressive megasequence (Araripe and Feijó, 1994; Cremonini et al., 1998; Soares et al., 2003). Major hiatuses exist within the transgressive megasequence in the Potiguar Basin (Pereira, 1994; Gil, 1996); these authors have interpreted a Late Turonian (ca. 89 Ma) subaerial unconformity developed across the Jandaıŕa Formation carbonate platform to be the result of tectonically-induced uplift and erosion across the margin. A short magmatic event (the ‘‘Cuó Volcanism’’) in the onshore Potiguar Basin around 93 Ma (Oliveira, 1998; Souza et al., 2004) has been interpreted to be the consequence of this tectonic event. Further, the formation of a widespread erosive unconformity at about 78 Ma across both the onshore and offshore Potiguar Basin has been attributed to plate tectonic reorganization of the central Atlantic (Gil, 1996). Cremonini and Karner (1995) and Cremonini (1996) pointed out that during the mid Campanian, the passage of an oceanic spreading center along the Equatorial Margin might have caused regional heating, uplift and erosion, as well as tectonic reactivation. The main expression of this event would be the raising diff --git a/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..08bae0555bf99692d0d40bd09fc4c6c267ab8dde --- /dev/null +++ b/outputs/multi_column/0845863d27c84b14011e17a388821525e783_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +![](figure) + +Fig. 4. Timing relationships between the main Phanerozoic tectono-thermal processes in the eastern Borborema Province, northeastern Brazil, compared to the onset of the cooling events identified by AFTA. Time constraints are compiled from Sial (1976), Long et al. (1986), Mizusaki (1989), Araripe and Feijó (1994), Feijó (1996), Oliveira (1993), Morais Neto (1999), Matos (1999, 2000), Hegarty et al. (2002), Lima Filho and Szatmari (2002), Souza et al. (2004), Jardim de Sá et al. (2004), and Almeida et al. (2005). + +related to rifting, post-rift tectonics, regional denudation, intrusive and extrusive magmatic activity, and localized hydrothermal fluid flow effects associated with all of these mechanisms can potentially have affected the Brazilian margin and adjacent interior. The sampling strategy adopted was designed such that the dominant heating or cooling effects on the Borborema Plateau area could be directly measured as opposed to being assumed or inferred from various basin models or crustal deformation schemes. + +## 4. Sampling details and background + +Fission-track samples were collected along two regional transects across the Borborema Plateau (Figs. 5 and 6). + +![](figure) + +Fig. 5. Location of AFTA (Apatite Fission-Track Analysis) samples from Borborema Province, NE Brazil (sample numbers shown as 4 to 36; full sample reference number is RD57-4 to RD57-36; CE, RN, PB and PE means, respectively, Ceará, Rio Grande do Norte, Paraı´ba and Pernambuco States). Samples consist of igneous and metamorphic Precambrian rocks (see Table 1 for details). Keys: (1) Borborema Plateau; (2) Interior lowlands; (3) Coastal cuestas (mainly Barreiras Fm); (4) Early Cenozoic mesas (Serra do Martins Fm); (5) Cretaceous basins; (6) Early Cretaceous Tholeiitic Dike Swarm; (7) Cenozoic volcanics. diff --git a/outputs/multi_column/0853d8a05fd1e839887d4bc3004a6770cb7b_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0853d8a05fd1e839887d4bc3004a6770cb7b_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..11af6128884f2ed1309ce2c025a5ff4bd3c5896c --- /dev/null +++ b/outputs/multi_column/0853d8a05fd1e839887d4bc3004a6770cb7b_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,57 @@ +and discussed. Section V concludes the paper. + +## II. THE ANALYZED GENERATOR + +We analyze the LCT attack on a noised pseudorandom sequence generator involving a primitive known as The Binary Rate Multiplier (BRM). BRM consists of 2 linear feedback shift registers (LFSRs). One of them, the clocking LFSR \((\text{LFSR}_{s})\), determines the clocking sequence for the clocked LFSR \((\text{LFSR}_{u})\), see Fig. 1. + +clk. + +LFSR + +LFSRs k positions u + +integer seq. + +![](figure) + +Fig. 1. The BRM primitive + +The BRM operates as follows (Fig. 2): Without clocking by \(\text{LFSR}_{s}\), the register \(\text{LFSR}_{u}\) produces the binary sequence \(u_{n}\). At the clock pulse \(i\) of \(\text{LFSR}_{s}\), the bits from \(k\) positions of \(\text{LFSR}_{s}\) determine the integer \(s_{i}\) that represents the number of bits from the sequence \(u_{n}\) that are going to be discarded. The integers \(s_{i},i=1,2,\ldots\) make the sequence \(s_{n}\). The process of discarding bits in this way is called non-uniform decimation of the sequence \(u_{n}\). The maximum value of the integer \(s_{i}\) determines the maximum number of bits from the sequence \(u_{n}\) that can be discarded at a time. The binary sequence \(z_{n}\) is the output sequence of the whole BRM. + +LFSRu + +LFSRs k positions un + +Non-uniform decimation zn + +sn + +![](figure) + +Fig. 2. Operation of the BRM + +The BRM primitive has become popular in the design of stream ciphers since it can be shown [2] that the produced sequence \(z_{n}\) has extremely long period and high linear complexity preserving at the same time good statistical properties of a single LFSR. + +## III. THE NEW LCT ATTACK + +In this section, we give details of the new LCT-based attack against a noised BRM. The general description and remarks about LCT have been exposed in the Introduction. To design an LCT attack against BRM, we have to determine which part of the BRM key (which consists of the initial states of \(\text{LFSR}_{s}\text{and LFSR}_{u}\), as usual) is to be guessed. It is shown in [5] that assigning a linear system to a BRM when the initial state of \(\text{LFSR}_{s}\) is guessed is easy. Then the unknowns in the system are the bits of the output sequence of \(\text{LFSR}_{u}\) without decimation together with the bits of the initial state of the same LFSR and the right-hand side of any equation in the system is the corresponding bit of the intercepted sequence. In our new LCT attack on a noised BRM, we use the same approach. We guess the initial state of \(\text{LFSR}_{s}\) and make a system of linear equations in the unknowns of the initial state of \(\text{LFSR}_{u}\) and the unknown bits of the output sequence of \(\text{LFSR}_{u}\) without decimation. The main point of our attack is the algorithm that eliminates the influence of the bits of the intercepted sequence complemented by noise. + +## Example 1 + +Suppose the BRM from Fig. 1 uses 4-bit LFSRs and the primitive feedback polynomials of \(\text{LFSR}_{s}\text{and LFSR}_{u}\) are \(f_{s}(x)=1+x+x^{4}\text{and}f_{u}(x)=1+x^{3}+x^{4}\), respectively. Let the number of output taps of \(\text{LFSR}_{s}\) be \(k=2\) and the tap positions are the first and the second (from the left). Let the initial states of \(\text{LFSR}_{s}\text{and LFSR}_{u}\) be 1010 and 0110, respectively. Then the clocking sequence for \(\text{LFSR}_{u}\) (i.e. the integer sequence \(s_{n})\) is \(31021002333\ldots\) and the output sequence of the BRM is \(11010110111\ldots\) Let the cryptanalyst’s guess of the initial state of \(\text{LFSR}_{s}\) be right, i.e. 1010. In the LCT attack against the generator without noise, the so-called decimation sequence is generated, containing the symbol ’2’ in the positions of the unknown bits. Each symbol ’2’ will correspond to a new variable in the system of equations assigned to the generator. In this case, the decimation sequence will be \(2222|\) 22212102212011220222122212221 \(\ldots\). The symbol | delimits the variables of the initial state of the clocked register \(\text{LFSR}_{u}\) from the rest of the variables. The variables to the left from the symbol | are given in the order \(x_{4},x_{3},x_{2},x_{1}\), whereas the variables to the right from the symbol | are given in the increased order of indexing, i.e. \(x_{5},x_{6}\), etc. Then the system of linear equations assigned to the given BRM is: + +\[\begin{aligned} x_{3}+x_{4}+x_{5}&=0 \\ x_{2}+x_{3}+x_{6}&=0 \\ x_{1}+x_{2}+x_{7}&=0 \\ x_{1}+x_{5}&=1 \\ x_{5}+x_{6}+x_{8}&=_{\ddots }0 \end{aligned}\] + +✷ + +The new ciphertext-only attack against a BRM is described below: + +1. Guess the initial state of the \(\text{LFSR}_{s}\). + +2. Set up a system of equations assigned to such a BRM without involving the intercepted bits. Such a system is homogeneous and always consistent. + +3. Set up a system of equations involving only the equations containing the intercepted bits. + +4. Join the obtained systems and check the consistency of the joint system. The following cases are possible: + +4. 1 There is no noise and the right initial state of \(\text{LFSR}_{s}\) was guessed - the joint system will be consistent and diff --git a/outputs/multi_column/0853d8a05fd1e839887d4bc3004a6770cb7b_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0853d8a05fd1e839887d4bc3004a6770cb7b_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..01ccd16cdf5f6ed9627fe8dcec57d9a9f1891f34 --- /dev/null +++ b/outputs/multi_column/0853d8a05fd1e839887d4bc3004a6770cb7b_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,30 @@ +TABLE I THE NUMBERS OF FALSE ALARMS OBTAINED WITH THE NEW LCT + +ATTACK (SEE TEXT) + +| | N | nf | nf % | ns | fs | fs% | +| --- | --- | --- | --- | --- | --- | --- | +| t = 1 | 20 | 1 | 5 | 2 | 1 | 5 | +| t = 2 | 190 | 62 | 33 | 5 | 2 | 1 | + +algorithm) \(n_{s}\) are given together with the numbers of cases \(f_{s}\), in which the false alarms were generated with the maximum number of solutions (that would be the worst possible case for the cryptanalyst). In the table, \(N\) represents the total number of possible combinations for complementing the bits of the intercepted sequence. From the Table I it can be noted that for \(t=2\) the number of false alarm cases is quite high, approx. 33% of all the cases. The maximum number of solution initial states of \(\text{LFSR}_{s}\) offered by the attack algorithm in that case is \(n_{s}=5\), which is \(1/3\) of the possible number of initial states of that register. This number is also quite high, but to recover from such a situation, ordering of these solution states according to the corresponding numbers of consistent systems obtained in the attack is possible to perform, which in most cases places the right initial state to the second position. This eliminates the problem of too many solutions offered by the attack algorithm and also makes the problem of too many false alarms easier. The greatest advantage of the new attack compared with the attack from [1] and [6] is in the fact that the new algorithm always produces the right solution, even when it is accompanied by a false alarm. + +## V. CONCLUSION + +In this paper, a new Linear Consistency Test (LCT)-based attack against a noised pseudorandom generator scheme employing irregular clocking is described and analyzed. The attack was applied against a specific representative of this class of generators known as The Binary Rate Multiplier (BRM). The attack first assigns a system of linear equations to the BRM based on a guessed initial state of its clocking LFSR. This system is then checked for consistency and if consistent, the right initial state of the clocking LFSR was guessed. If the obtained system is inconsistent, the equations involving complemented bits of the intercepted sequence are eliminated from the system and then the consistency of the system is checked again. Which bits of the intercepted sequence are complemented is also guessed. If the guess of those bits is right, the obtained system will surely become consistent. Otherwise, if the guess of the initial state of the clocking LFSR was right, there is a significant chance that the newly obtained system becomes consistent. In a contrary case, the new system will be inconsistent with high probability. The attack always gives the right solution for the initial state of the clocking LFSR, but that solution may be accompanied by other solutions (false alarms). The recovery procedure in those cases is proposed as well. The attack is feasible if the number of possible combinations for the bits of the intercepted sequence complemented by noise is small, which means that the level of noise is up to moderate. + +# REFERENCES + +[1] G. Bu, ”Linear consistency test (LCT) in cryptanalysis of irregularly clocked LFSRs in the presence of noise, ” Master thesis, Gjøvik University College, Gjøvik, Norway, 2011. + +[2] W. Chambers and S. Jennings, ”Linear equivalence of certain BRM shift-register sequences, ” Electronics Letters, vol. 20, no. 24, pp. 1018–1019, 1984. + +[3] J. Golić and M. Mihaljević, ”A generalized correlation attack on a class of stream ciphers based on the Levenshtein distance, ” Journal of Cryptology, vol. 3, no. 3, pp. 201–212, 1991. + +[4] T. Johansson, ”Reduced complexity correlation attacks on two clock-controlled generators, ” in: Ohta K. (Ed.), Advances in Cryptology: Proceedings of ASIACRYPT ’98, Lecture Notes in Computer Science LNCS 1514, pp. 342–356, Springer–Verlag, 1998. + +[5] H. Molland, T. Helleseth, ”An improved correlation attack against irregular clocked and filtered keystream generators, ” in Proceedings of CRYPTO 2004, Lecture Notes in Computer Science LNCS 3152, pp. 373–389, Springer–Verlag, 2004. + +[6] S. Petrović, ”Application of linear consistency test in a ciphertext-only attack on irregularly clocked linear feedback shift registers, ” in Proceedings of XII Spanish Conference on Cryptography and Information Security (RECSI2012), U. Zurutuza, R. Uribeetxeberria, I. Arenaza-Nuño, Eds. Arrasate - Mondragon: Servicio Editorial de Mondragon Unibertsitatea, pp. 113-117, 2012. + +[7] K. Zeng, C. Yang, and T. Rao, ”On the linear consistency test (LCT) in cryptanalysis with applications, ” in Advances in Cryptology, Proceedings of CRYPTO ’89, Lecture Notes in Computer Science LNCS 435, pp. 164–174, Springer–Verlag, 1990. diff --git a/outputs/multi_column/08742748046a770dbea7ee3f3eddd56403cc_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/08742748046a770dbea7ee3f3eddd56403cc_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..479cd57d0790b59291778848bc0f333393db8d13 --- /dev/null +++ b/outputs/multi_column/08742748046a770dbea7ee3f3eddd56403cc_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,51 @@ +| PCTP 125, 143–4 | pyrolysis 431–2 | +| --- | --- | +| peptide Gd-chelate conjugates 321–6, 328–9, 332–4 perfluorocarbon 455, 458, 463, 466, 472–4, 476, 479 | pyrophosphate anions 372 | +| permeability 454, 457, 465 | | +| | q = 2 complex 315, 336, 339 | +| peroxidases 373, 374 | quantum dots 458, 472, 475 | +| PET 344, 358 | q-values See hydration number | +| pH dependence 56–7 | | +| pH sensing 349 | radiofrequency pulse 2, 12 | +| phage display 320, 325 | ratiometric method 344, 357, 359 | +| phase encoding 8 | reaction | +| phosphatidylcholine (PC) 455, 463 | carbon template 103–6, 107, 123–4 | +| phosphatidylethanolamine (PE) 455, 457, 463, 465, | click 100, 102, 137 | +| 467–9, 471, 473–5, 477 | crab-like 103, 105–6 | +| phosphatidylserine (PS) 469, 471, 476–7 | Kabachnik-Fields 98 | +| phosphinic acids 98–9, 111, 119–21, 128–9, 135–6, | Mannich 89, 96, 98, 109, 119, 121, 125, 127–8, | +| 142, 144 | 133 | +| phospholipids 455 | Moedritzer-Irani 98 | +| phosphonic acids 98–100, 102, 111–12, 114–16, | Richman-Atkins 103–5, 123, 125–7 | +| 119–23, 125–8, 142–4 | Redfield approximation 285–7 | +| photochemical activation (PCA) 473 | relativistic effects 211–12 | +| pH-potentiometry 171, 189 | relaxation | +| 31P NMR 349 | Curie mechanism 216, 220, 228, 244, 258 | +| polarizable continuum model (PCM) 212–13, 232, 243 | dipolar mechanism 221 | +| poly β-cyclodextrin 355 | electronic 220–221, 242 | +| poly(ethyleneglycol) (PEG) 451, 457, 460, 463, 478 | hyperfine (scalar) mechanism 220 | +| polyatomic molecules 292 | inner-sphere 219 | +| polymeric coating 432–3 | longitudinal 216, 218–21, 236 | +| polymers 53, 59, 70, 71 | outer-sphere 219, 221 | +| copolymers 53, 63, 70 | transverse 219–21 | +| linear 59–60, 63, 70 | relaxation rate 29, 39, 40, 42, 48, 72 | +| porphyrin 361 | relaxation theory 30 | +| positron emission tomography (PET) 449, 479 | relaxation times 4 | +| Primovist 84 | relaxivity 26–7, 454–5, 460, 464–7, 472–4, 478–9, | +| Pr-MOE-DO3A 346 | 482 | +| probe solute 292–7, 299–302 | inner-sphere 297–8 | +| ProHance 84, 117 | outer-sphere 289–7, 299–302 | +| protein binding affinity 314–5, 319–21, 323–6, 328, | profile 299–300 | +| 336 | quenching 295–300 | +| protein bound 54, 61, 70, 72–3 | second-sphere 297–300 | +| protein concentration 313, 320, 325 proton density (ρ) 13, 14, 16–19 | relaxometry 463, 465–8, 470 repetition time, see TR | +| proton density weighting 16–17, 19 | responsive agents 405–6 | +| proton exchange 29–31, 39, 55–6, 73 | reticulo-endothelial system (RES) 452, | +| versus water exchange 56 | 478 | +| proton relaxation enhancement (PRE) effect 314 | RGD peptide 328–9 | +| proton relaxivity 26, 28–31, 37, 56–7, 66, 69, 75 | RIME effect 333 | +| proton resonance frequency (PRF) 344 | rotating frame 2 | +| pseudo-rotation 283, 288–9 | rotation of dimers 59 | +| pulse sequences 11–15, 21–23 | rotation of monomers 59 | +| pyclene 123–7, 143–4 | rotational correlation time 27, 29, 31, 33, | +| pyridine 37, 51 | 57–60 | diff --git a/outputs/multi_column/08c9eac4149a44cf8eed7cf1466ce8afa6b7_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/08c9eac4149a44cf8eed7cf1466ce8afa6b7_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2c0c2162630c578c9574f7d847252c8af84d4129 --- /dev/null +++ b/outputs/multi_column/08c9eac4149a44cf8eed7cf1466ce8afa6b7_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,33 @@ +![](figure) + +![](figure) + +Issue Number 1, 2006 + +# IMMEDIATE PAST PRESIDENT’S MESSAGE + +![](figure) + +![](figure) + +Dear OPCC members, + +My last five years as a member of OPCC have been very enjoyable and rewarding. I have met many talented people and have made many friends, and have learned more about photography than I had hoped for. + +There have been a lot of changes in my life in the last two years, and I have decided to move from western Washington where I have lived all my life to Carlsbad, California. I have some family in the area and had met a friend there last year. She is a world traveler and an avid photographer. But the Northwest will always be my "home". + +The travel bug is still with me having traveled to Europe, Africa, South America and Antarctica since we last met and with a few weeks in Southeast Asia scheduled for February. + +I will send Jim my email address once I get settled so we can keep in contact. Thanks again for the friendships and I wish all of you a Great Christmas and all the best in the New Year. + +Bob Mandich + +________________________________________________________________________ + +# SENSOR DUST + +Bob Huelsdonk + +Last January, I submitted a digital projected competition print from my digital Canon D60 SLR which showed some wind generators against a plain blue sky. Two of our discerning members, Jean Timmermeister and Valerie Henschel commented that the sky had a dim but noticeable dust spot on it. I had not noticed it on my computer screen or even on the projected image until it was pointed out. + +Returning home, I put the print on my computer screen. Indeed it showed as about a 1/2 inch, slightly darker blob (on an 8x10 image). I then increased the contrast greatly, and lo and diff --git a/outputs/multi_column/0904c7071324813f138e96ed004bbc613748_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0904c7071324813f138e96ed004bbc613748_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fa42cf1986378c3adb5bc5d4e7a0fc0d0372010c --- /dev/null +++ b/outputs/multi_column/0904c7071324813f138e96ed004bbc613748_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +![](figure) + +Fig. 2. Forward \((\Omega_{+})\), backward \((\Omega_{-})\) and local Alfvén frequency (thick line) as a function of the radial position. The arrows indicate the location of the resonances. In this plot \(v_{i}/v_{Ai}=0.02,l/R=0.1,l^{}/R=0.01\), L = 100R and \(\rho_{i}/\rho_{e}=3\). The dotted vertical lines mark the limits of the inhomogeneity of the flow. + +has been assumed a discontinuous flow (at the boundary of the loop), except by Erdélyi & Taroyan (2003a,b) who considered a linear profile to model MHD waves in the Earth’s magnetotail. For the profiles given by Eqs. (11) and (12) it turns out that Eq. (9) is a transcendental equation for the resonant position rA. This equation is solved using standard numerical techniques. Depending on the spatial scales of the density and velocity we distinguish two different regimes, \(l^{}\times l\) and the asymptotic case + +\(l^{}*l\). The analysis of the first situation is rather simple (see also Peredo & Tataronis 1990), since the the forward propagating wave has always a single resonant position in the range R < \(r_{A} + +Question Documents Answer(s) Relax False? Abductive Parser Question Semantic Logic Question Form Document Collection Prover True? Rules Transformation Transformation Index Answer Answer Lexico-semantic Logic Form Semantic Patterns IR Search Transformation Transformation Question Engine Class World Knowledge Parser Taxonomies Question Recognition Expanded Question 1 Keywords 1 Paragrah Ordering Axioms Answer set 1 Answers Word Classes Question Expanded Question 2 Keywords 2 Answer set 2 Combine Rerank / ✗ Expansion Answer Answers Expanded Question n Keywords 1 Extraction Answer set n ↑ ✓ → ↑ ← + + +Parser Question Semantic Question Logic Form + + + +Relax False? Abductive Rules Prover True? + + +Lexico-semantic Patterns Question Taxonomies Word Classes Transformation Transformation Expansion Question Question Recognition Class Expanded Question 2 Expanded Question n Expanded Question 1 + + + +Answer Answer Logic Form Semantic Transformation Transformation World Knowledge Parser Axioms Answer set 1 Answers Combine / Answer set 2 Rerank Answers Answer set n + + + + +Keywords 1 + + + + + +Keywords 2 + + + + + + + + + + +Knowledge-Based Question Processing + +Shallow Document Processing + +Knowledge-Based Answer Processing + +Figure 1: An architecture for knowledge-based Question/Answering + +uments containing the required information, based on keywords techniques. Q/A systems are presented with natural language questions, far richer in semantics than a set of keywords eventually structured around some operators. Furthermore, the output of Q/A systems is either the actual answer identified in a text or small text fragments containing the + +answer. This eliminates the user's trouble of finding the required information in sometimes large sets of retrieved documents. Open-domain Q/A systems must also be distinguished, on the other hand, from IE systems that model the information need through database templates, thus less naturally than a textual answer. Moreover, open-domain IE is still difficult to achieve, because its linguistic pattern recognition relies on domain-dependent lexico-semantic knowledge. To be able to satisfy the open-domain constraints, textual Q/A systems replace the linguistic pattern matching capabilities of IE systems with methods that rely on the recognition of the question type and of the expected answer type. Generally, this information is available by accessing a classification based on the question stem (i.e. what, how much, who) and the head of the first noun phrase of the question. Question processing also includes the identification of the question keywords. Empirical methods, based on a set of ordered heuristics operating on the phrasal parse of the question, extract keywords that are passed to the search engine. The overall precision of the Q/A system depends also on the recognition of the question focus, since the answer extraction, succeeding the IR phase, is centered around the question focus. Unfortunately, empirical methods for focus recognition are hard to develop without the availability of richer semantic knowledge. Special requirements are set on the document processing component of a Q/A system. To speed-up the answer extraction, the search engine returns only those paragraphs from a document that contain all queried keywords. The paragraphs are ordered to promote the cases when the keywords not only are as close as possible, but also preserve the syntactic dependencies recognized in the question. Answers are extracted whenever the question topic and the answer type are recognized in a paragraph. Thereafter the answers are scored based on several bag-of-words heuristics. Throughout all this processing, the NLP techniques are limited to (a) named entity recognition; (b) semantic classification of the question type, based on information provided by an off-line question taxonomy and semantic class information available from WordNet (Fellbaum 1998); and (c) phrasal parsing produced by enhancing Brill's part-of-speech tagger with some rules for phrase formation. However simple, this technology surpasses 75% precision on trivia questions, as posed in the TREC-8 competition (cf. (Moldovan et al.1999)). An impressive improvement of 14% is achieved when more knowledge-intensive NLP techniques are applied at both question and answer processing level. Figure 1 illustrates the architecture of a system that has enhanced Q/A performance. As represented in Figure 1, all three modules of the Q/A system preserve the shallow processing components that determine good performance. In the Question Processing module, the Question Class recognizer, working against a taxonomy of questions, diff --git a/outputs/multi_column/09f90a8fad0997f7cf454cbcbe79cab3bc0f_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/09f90a8fad0997f7cf454cbcbe79cab3bc0f_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b17391eeea2f96824b5b434b6b2326e8ee31f5ab --- /dev/null +++ b/outputs/multi_column/09f90a8fad0997f7cf454cbcbe79cab3bc0f_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,60 @@ +## 5 Evaluation + +Both qualitative and quantitative evaluation of the integration of surface text-based and knowledge-based methods for Q/A is imposed. Quantitatively, Table 3 summarizes the scores obtained when only shallow methods were employed, in contrast with the results when knowledge-based methods were integrated. We have separately measured the effect of the integration of the knowledge-based methods at question processing and answer processing level. We have also evaluated the precision of the system when both integrations were implemented. The + +results were the first five answers returned within + +250 bytes of text, when approximatively half million TREC documents are mined. We have used the 200 questions from TREC-8, and the correct answers provided by NIST. The performance was measured both with the NIST scoring method employed in the TREC-8 and by simply assigning a score of 1 for the question having a correct answer, regardless of its position. + +| | Percentage of correct answers in top 5 returns | NIST score | +| --- | --- | --- | +| Text-surface-based | 77.7% | 64.5% | +| Knowledge-based Question Processing (only) | 83.2% | 71.5% | +| Text-surface-based only with Answer Justification | 77.7% | 73% | +| Knowledge-based Question Processing with Answer Justification | 89.5% | 84.75% | + +Table 3: Accuracy performance + +When using the NIST scoring method to evaluate an individual answer, we used only six values:(1; :5; :33; :25; :2; 0), representing the score the answer's question obtains. If the first answer is correct, it obtains a score of 1, if the second one is correct, it is scored with :5, if the third one is correct, the score becomes :33, if the fourth is correct, the score is :25 and if the fifth one is correct, the score is :2. Otherwise, it is scored with 0. No credit is given if multiple answers are correct. Table 3 shows that both knowledge-based methods enhanced the precision, regardless of the scoring method. To further evaluate the contribution of the justification option, we evaluated separately the precision of the prover for those questions for which the surface-text-based methods of our system, when operating alone, cannot find correct answers. We had 45 TREC-8 questions for which the evaluation of the prover was performed. Table 4 summarizes the accuracy of the prover. + +| | Proven correct | Proven incorrect | Precision | +| --- | --- | --- | --- | +| Incorrect answers (no knowledge) | 3 | 210 | 98.5% | +| Correct answers (KB-based) | 127 | 5 | 96.2% | +| Incorrect answers (KB-based) | 4 | 38 | 90.04% | + +Table 4: Prover performance + +Qualitatively, we find that the integration of knowledge-based methods is very beneficial. Table 2 + +illustrates the correct answer obtained with these methods, in contrast to the incorrect answer provided when only the shallow techniques are applied. + +## 6 Conclusions + +We believe that the performance of a Q/A system depends on the knowledge sources it employs. In this paper we have presented the effect of the integration of knowledge derived from question taxonomies and produced by answer justifications on the Q/A precision. Our knowledge-based methods are lightweight, since we do not generate precise semantic representations of questions or answers, but mere approximations determined by syntactic dependencies. very simple logical representations, in which syntactic and semantic ambiguities are completely ignored. Nevertheless, we have shown that these approximations are functional, since we implemented a prover that justifies answers with high precision. Similarly, our knowledge-based question processing is a mere combination of word class information and syntactic dependencies. + +Furthermore, our prover operates on + +# References + +Michael Collins. A New Statistical Parser Based on Bigram Lexical Dependencies. In Proceedings of the 34st Annual Meeting of the Association for Computational Linguistics, ACL-96, pages 184{191, 1996. + +Christiane Fellbaum (Ed). WordNet - An Electronic Lexical Database. MIT Press, 1998. + +Jerry R. Hobbs. manuscript, 1986. + +Discourse and Inference. + +Unpublished + +Jerry R. Hobbs. Overview of the TACITUS Project. In Computational Linguistics, 12:(3), 1986. + +Jerry Hobbs, Mark Stickel, Doug Appelt, and Paul Martin. Interpretation as abduction. Artificial Intelligence, 63, pages 69{142, 1993. + +Wendy Lehnert. Lawrence Erlbaum Publishers, 1978. + +The processing of question answering. + +Dan Moldovan, Sanda Harabagiu, Marius Paşca, Rada Mihalcea, Richard Goodrum, Roxana G^ırju and Vasile Rus. Lasso: a tool for surfing the answer net. In Proceedings of TREC-8, 1999. + +Ellen Riloff and Rosie Jones. Learning Dictionaries for Information Extraction by Multi-Level Bootstrapping. In Proceedings of the 16th National Conference on Artificial Intelligence, AAAI-99, 1999. diff --git a/outputs/multi_column/0a2b678b6c6825364a5a18154dd59064922e_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0a2b678b6c6825364a5a18154dd59064922e_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..243b66b3afcc1aff5cb5e778ed1fca367040824a --- /dev/null +++ b/outputs/multi_column/0a2b678b6c6825364a5a18154dd59064922e_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,21 @@ +# Expression of Minichromosome Maintenance Protein 7 and Smad 4 in Squamous Cell Carcinoma of the Esophagus + +## Ji Hyun Ahn∙Hee Kyung Chang + +Department of Pathology, Kosin University College of Medicine, Busan, Korea + +Background : Minichromosome maintenance protein 7 (MCM 7) performs a direct role in the initiation of DNA replication, which suggests that it may prove useful as a marker of cell proliferation. Smad 4 is a tumor suppressor gene that mediates the transforming growth factor b pathway. The principal objective of this study was to characterize the expression of MCM 7 and Smad 4 and to analyze their relationship to clinicopathological parameters in patients with esophageal squamous cell carcinoma. Methods : Expression levels of MCM 7 and Smad 4 were evaluated via immunohistochemistry on formalin-fixed and paraffin-embedded tissues from 67 cases of esophageal squamous cell carcinoma. Results : High levels of MCM 7 expression were detected in 53 cases (74.6%), and were associated with higher T stages (p = 0.030). Kaplan-Meier survival curves demonstrated that patients with higher levels of MCM 7 expression had poorer prognoses, although this association was not significant (p = 0.086). Loss of Smad 4 expression was noted in 18 cases (23.4%), and was not associated with clinicopathological characteristics, including MCM 7 expression, or prognosis. Conclusions : MCM 7 expression is associated with the invasiveness of esophageal squamous cell carcinoma. Altered expression of Smad 4 does not appear to have pathobiological significance in esophageal carcinoma. + +Received : December 15, 2009 Accepted : February 16, 2010 + +## Corresponding Author + +Hee Kyung Chang, M.D. Department of Pathology, Kosin University College of Medicine, 34 Amnam-dong, Seo-gu, Busan 602-702, Korea + +Key Words : MCM protein 7, human; Smad 4 protein, human; Carcinoma, squamous cell; + +Tel: 051-990-6323 Fax: 051-241-7420 E-mail: changhkg@ns.kosinmed.or.kr + +Esophageal neoplasms + +Esophageal cancer is the 9th most common cancer in Korean males.1 Squamous cell carcinoma is the most common histological type worldwide, including in Korea. Risk factors thus far identified are cigarettes, alcohol, lack of vitamin A, C, and E, lack of folic acid, a history of achalasia, corrosive esophagostenosis, hyperkeratosis, Plummer-Vinson syndrome, and head and neck tumors.2-4 The esophagus lacks a serosal layer, although the lymphatic channels are well-developed, and early-stage esophageal cancer spreads readily into the adjacent organs, thus resulting in an overall poor prognosis. This poor prognosis issue persists, despite recent improvements in surgical methods and therapeutic agents.5 Although several previous studies have focused on the identification of prognostic molecular markers in this cancer, no significant prognostic markers have yet been identified. The minichromosome maintenance (MCM) complex is a DNA-binding heterohexamer complex formed by minichromosome maintenance proteins 2-7 (MCM 2-7). The MCM complex functions as a “licensing factor,” which allows the initiation of DNA replication. During cell division, it allows only one DNA replication per cycle. The MCM complex combines with the origin recognition complex, Cdc 6, and Cdt 1 to form the prereplicative complex (pre-RC).6-10 Once the pre-RC is built up, the initiation of DNA replication is permitted. During DNA synthesis, the MCM complex dissociates from the replication origin, thereby preventing replication from occurring until the cell achieves the G1 phase of the next cycle.6-10 MCM proteins are thought to be useful markers for proliferation, as it has been demonstrated in replicating but not quiescent cells.11-13 Additionally, MCM proteins are utilized as markers for the diagnosis of invasive cancer and carcinoma in situ. Recent studies have demonstrated an increase in MCM proteins in malignant tumors such as adenocarcinoma of the lung, colon, and prostate, papillary thyroid carcinoma and endometrial carcinoma.11-16 A few studies have also evaluated the expression of MCM 2, 4, and 5 in esophageal squamous cell carcinoma, but, to the best of our knowledge, no research into MCM 7 expression in esophageal carcinoma has been reported thus far in the English-language literature.17-19 The transforming growth factor b (TGF-b)/Smad pathway is diff --git a/outputs/multi_column/0a2b678b6c6825364a5a18154dd59064922e_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/0a2b678b6c6825364a5a18154dd59064922e_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..93205f29b1c43447bf9d11ac67f81b00d444a39c --- /dev/null +++ b/outputs/multi_column/0a2b678b6c6825364a5a18154dd59064922e_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +of Smad4, a TGF-beta signaling molecule, in oral squamous cell carcinoma. J Oral Sci 2006; 48: 105-9. + +22. Kloth JN, Kenter GG, Spijker HS, et al. Expression of Smad2 and + +Smad4 in cervical cancer: absent nuclear Smad4 expression correlates with poor survival. Mod Pathol 2008; 21: 866-75. + +23. Koorstra JB, Hustinx SR, Offerhaus GJ, Maitra A. Pancreatic carcinogenesis. Pancreatology 2008; 8: 110-25. + +24. Massagué J. G1 cell-cycle control and cancer. Nature 2004; 432: 298-306. + +25. Wakefield LM, Roberts AB. TGF-beta signaling: positive and negative effects on tumorigenesis. Curr Opin Genet Dev 2002; 12: 22-9. + +26. Qiu W, Schönleben F, Li X, Su GH. Disruption of transforming + +growth factor beta-Smad signaling pathway in head and neck squamous cell carcinoma as evidenced by mutations of SMAD2 and SMAD4. Cancer Lett 2007; 245: 163-70. + +27. Wang LH, Kim SH, Lee JH, et al. Inactivation of SMAD4 tumor + +suppressor gene during gastric carcinoma progression. Clin Cancer Res 2007; 13: 102-10. + +28. Alazzouzi H, Alhopuro P, Salovaara R, et al. SMAD4 as a prognostic marker in colorectal cancer. Clin Cancer Res 2005; 11: 2606-11. + +29. Natsugoe S, Xiangming C, Matsumoto M, et al. Smad4 and transforming growth factor beta1 expression in patients with squamous cell carcinoma of the esophagus. Clin Cancer Res 2002; 8: 1838-42. + +30. Osawa H, Shitara Y, Shoji H, et al. Mutation analysis of transforming growth factor beta type II receptor, Smad2, Smad3 and Smad4 in esophageal squamous cell carcinoma. Int J Oncol 2000; 17: 723-8. diff --git a/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2ebfdbd96e7060cf3adc7e0997cfc3f513901004 --- /dev/null +++ b/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +## Midgut Gland Samples + +Farmed Litopenaeus vannamei in intermolt state (Chan et al., 1988) and weighing 25 g, were kept in 1500 L circular flat-bottom tanks at 288C, 30& salinity, and oxygen saturation. Organisms were fed twice a day at 8:00 and 17:00 with PIASA feed: 40% protein, 7% lipid, 3% fiber, 12% water, 11% ash, and 27% free nitrogen extract. Organisms were starved for 24 h prior to trypsinogen testing by Western blot. Organisms were decapitated, and the midgut glands were excised and homogenized in acetone 2:1 (v:w) at 48C to precipitate proteins. The precipitate was dissolved in 20 mM ethylenediamine-tetraacetic acid (EDTA) in PBS, denatured in Laemmli sample buffer, and analyzed immediately. For immunohistology, one group of 40 organisms was starved 24 h, and a second group of 40 was killed 3 h after feeding. + +## Electrophoresis and Immunoblotting + +Protein from 30 midgut gland extracts was analyzed by discontinuous sodium dodecil sulphate polyacrylamide gel electrophoresis (SDS-PAGE) using 12% acrylamide (Laemmli, 1970). Twenty lg of protein from the 10-lL midgut gland extracts was mixed (1:2) (v:v) with Laemmli loading buffer (125 mM Tris HCl, pH 6.8, 4% SDS, 10% bmercaptoethanol, 20% glycerol, 0.02% bromophenol blue) and heated for 2 min at 958C. Electrophoresis was carried out for 2 h at 20 mA and 48C. Protein was visualized by staining with Coomassie Brilliant Blue R-250. Protein was also transferred onto a polyvinylidene fluoride membrane for Western blotting (Towbin et al., 1979). Transfer efficiency was evaluated by Ponceau staining. Membranes were blocked with skim milk (PBS, 0.2% Tween 20, 5% skim milk, pH 7.2) and incubated with anti-TAP or anti-IP diluted 1:3000 in PBS-Tween (PBS, 0.2% Tween 20, pH 7.2). Antibodies blocked with their antigens were used as controls. Membranes were washed with PBS-Tween three times for 20 min and incubated with anti-rabbit-IgG-HRP diluted 1:5000 in PBS-Tween. Specific peptides were detected using 3,3,diaminobenzidine 0.6 mg/mL in PBS, at pH 7.4 with 0.03% NiCl2 and 0.2% H2O2 as the substrate for HRP (Harlow and Lane, 1988). + +## Immunohistochemistry + +Midgut glands of 40 fed and 40 starved organisms were dissected and fixed for 36 h in formaldehyde diluted to 3.7% with seawater. Fixed tissues were dehydrated in increasing concentrations of ethanol at room temperature and embedded in paraffin. Serial cuts of 3 lm were obtained from each midgut gland. Slices were mounted on glass slides and dried for 16 h at room temperature. After paraffin removal with xylol and passage through another dehydration series, sections were treated in serial order to obtain images of cells stained with hematoxylin-eosin, anti-TAP, and anti-IP antibodies diluted 1:200 in PBS for 2 h at room temperature. Controls were incubated with normal rabbit serum, with first antibody omitted or blocked with its antigen (Harlow and Lane, 1988). After thorough rinsing with PBS, sections were incubated with anti-rabbit-HRP, diluted 1:3000 in PBS. Finally, sections were washed with PBS. Antibody-reactive molecules were indicated by chromogenic reaction of HRP (Harlow and Lane, 1988). Photos were taken with a light microscope at 203 magnification (BX41 Olympus). Images were obtained with a 1.4 megapixel CoolSNAP-Pro cooled CCD camera, utilizing Image-Proplus 4.1 Olympus software. + +# RESULTS + +Based on results of the ELISA technique (Harlow and Lane, 1988), antibodies elicited against TAP and IP had titers of 1:3200 against the synthesized peptides. No cross-reaction was observed when IP antibodies were tested with synthesized TAP or when TAP-antibodies were tested against synthesized IP. Control sera reacted negatively against both synthesized IP and TAP. Both TAP and IP-antibodies reacted negatively when tested with bovine chymotrypsin. The SDS-PAGE of midgut gland extract showed a complex protein composition, related to both size and concentration (Fig. 2, Lane I). Western blots for the same extract displayed three bands (Mr 29.7, 30.2, and 32.9) when anti-TAP antibodies were used (Fig. 2, Lane II). Two proteins were displayed when using anti-IP antibodies against the crude extract (Fig. 2, Lane III). The molecular mass of the two proteins was the same as those of the two heavier proteins displayed by the anti-TAP antibodies (30.2 and 32.9 kDa). The anti-TAP antibodies detected no protein when extracts were not prepared by precipitation with acetone. No signal was observed when blots were treated with control sera or with antibodies previously incubated with synthesized peptides. The different cell types were identified by histology when samples were stained with hematoxylin and eosin (Figs. 3A, 4A). The figures show transverse 3-lm paraffin serial sections of midgut glands. Cell type was classified according to Bell and Lightner (1988). The B cells contained one very large vacuole, typically having a highly convex lumen surface, and the nucleus was displaced peripherally toward the basal region of the cell. The F cells had a prominent basal nucleus and were fibrous in appearance, with strongly basophilic cytoplasm. The 80 shrimp analyzed presented reactive molecules with both anti-peptide antibodies only in secretory B cells of both fed and starved organisms (Figs. 3, 4). The figures show equivalent areas of serial cuts, although the pictures displayed (B, C, and D) are slightly displaced. When animals were fed (Fig. 4), it was possible to recognize feed in the lumen. Some B cells in both corresponding positions were stained with the antibodies (Figs. 4B, C), and the feed was also reactive. Controls with antiserum blocked by the respective antigen (IP or TAP) showed no positive result (Figs. 3D, 4D). diff --git a/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d1dafd3bc22e75e8a13b0b55556a894ebeb0d90b --- /dev/null +++ b/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,11 @@ +![](figure) + +![](figure) + +Fig. 2. SDS-PAGE (a) and Western blot (b) of proteins from L. vannamei midgut gland. MWM, molecular weight marker; I, Coomassie stained; II, TAP antibody labeled; III, IP antibody labeled. Arrows indicate the different bands. + +Granules, containing aggregated molecules (Fig. 5), were darker than the cytoplasm background. Similar cells in different sections of the midgut gland were labeled with both treatments. + +# DISCUSSION + +Results showed that the L. vannamei midgut gland synthesizes and stores trypsinogen to keep trypsin inactive while stored and ready to be secreted and activated. Evidence of trypsinogen storage in the penaeid midgut gland is provided by Western blot analysis and immunohistology. As shown in Fig. 1, anti-TAP antibodies specifically detected trypsinogen only, but anti-IP detected both trypsin and trypsinogen. The criterion to identify a true trypsinogen molecule was that antibodies had no cross-reaction, and that the antibody against the trypsinogen activation peptide detected the same molecule as the internal peptide antibody elsewhere in the Western blot (molecular weight) or the immunohistology (cells stained). Antibodies generated by the two peptides were specific and were suitable for distinguishing two different sequences in the trypsin molecule, one of them specific to the inactive form of trypsin. Trypsinogen purification was not possible (Klein et al., 1996), but eliciting antibodies from synthetic peptide was an option. Detection of L. vannamei trypsinogen is difficult because it is activated quickly, possibly by itself (Van Wormhoudt et al., 1995). To prevent possible activation during homogenization, protein from the midgut gland was precipitated with acetone, and EDTA, reducing agents, and heat were used. These treatments eliminated enzyme activity by chelating calcium ions needed for trypsin stabilization (Rypnieswski et al., 1994), breaking disulfide bonds, and denaturing protein. The trypsin activation peptide sequence is different among species. In vertebrates, the peptide is small, around six amino acid residues long, and highly acidic because of the Asp content (Light and Janska, 1989). The enzyme enteropeptidase is responsible for cleavage and activation of trypsinogen because of its high and precise affinity for the peptide bond linking the trypsinogen activation peptide and the enzyme forming the trypsinogen (Light and Janska, 1989). In L. vannamei, the activation peptide is larger, with 14 amino acid residues, and the composition suggests that the activation enzyme is trypsin itself, in contrast to vertebrate trypsinogen that protects itself from activation (Light and Janska, 1989; Van Wormhoudt et al., 1995; Klein et al., 1996). By comparing the pattern of the total protein stained with Coomasie with that of proteins labeled with antibodies by Western blot, it was observed that trypsin sequences obtained by Klein et al. (1996) were transcribed in the midgut gland of L. vannamei. Substrate gel electrophoresis analysis and inhibition (Lemos et al., 2000) showed that at least three different trypsins were present, as demonstrated by Le Moullac et al. (1996). The mass of denatured trypsins detected by Western blot analysis was similar to that estimated for the trypsin pool (30 kDa) by Klein et al. (1996). Three protein bands were detected with anti-TAP, and two protein bands of sizes close to those of the two heavier proteins detected with anti-TAP were detected with anti-IP antibodies. Differences in band number could be related to differences in trypsin isoforms among IP sequences (Klein et al., 1996). The TAP sequence was conserved in the diff --git a/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d8f6a256274bf854c08ba63e2dc56a0726cc19d6 --- /dev/null +++ b/outputs/multi_column/0a6b833c50bc059f767492f394fe06302113_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,31 @@ +Le Moullac, G. L., B. Klein, D. Sellos, and A. Van Wormhoudt. 1996. Adaptation of trypsin, chymotrypsin and a-amylase to casein level and protein source in Penaeus vannamei (Crustacea Decapoda).—Journal of Experimental Marine Biology and Ecology 208: 107–125. + +Light, A., and H. Janska. 1989. Enterokinase (enteropeptidase): comparative aspects.—Trends in Biochemical Sciences 14: 110–112. + +Lu, P. J., H. C. Liu, and I. H. Tsai. 1990. The midgut trypsins of shrimp (Penaeus monodon). High effieciency toward native protein substrates including collagens.— Biological Chemistry 371: 851–859. + +Martin, D. W., V. W. Rodwell, and P. A. Mayer. 1982. Bioqúımica de Harper, El manual moderno S.A de C.V. Mex. Mex. 633 pp. + +Muller, H. M., J. M. Crampton, A. della Torre, R. Sinden, and A. Crisanti. 1993. Members of a trypsin gene family in Anopheles gambiae are induced in the gut by blood meal.—European Molecular Biology Organization Journal 12: 2891–2900. + +Noriega, F. G., and M. A. Wells. 1999. A molecular view of trypsin synthesis in the midgut of Aedes aegypti.— Journal of Insect Physiology 45: 613–620. + +Pérez Farfante, I., and B. Kensley. 1997. Penaeoid and Sergestoid Shrimps and Prawns of the World. Keys and Diagnoses for the Families and Genera. Memoires du Museum National d’Historie Naturelle, Paris, France. 233 pp. + +Rypniewski, W. R., A. Perrakis, C. E. Vorgias, and K. S. Wilson. 1994. Evolutionary divergence and conservation of trypsin.—Protein Engineering 7: 57–64. + +Secor, S. M. 2001. Regulation of digestive performance: a proposed adaptive response.—Comparative Biochemistry and Physiology Part A 128: 565–577. + +- ——, and J. M. Diamond. 2000. Evolution of regulatory responses to feeding in snakes.—Physiological and Biochemical Zoology 73: 123–141. + +Tidwell, J. H., and G. L. Allan. 2001. Fish as food: aquaculture’s contribution. Ecological and economic impacts and contributions of fish farming and capture fisheries.—European Molecular Biology Organization Reports 2: 958–963. + +Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.— Proceedings of the National Academy of Sciences of the United States of America 76: 4350–4354. + +Tsu, C. A., and C. S. Craik. 1996. Substrate recognition by recombinant serine collagenase from Uca pugilator.— Journal of Biological Chemistry 271: 11563–11570. + +Wormhoudt, A. Van, D. Sellos, A. Donval, S. Plaire-Goux, and G. Le Moullac. 1995. Chymotrypsin gene expression during the intermolt cycle in the shrimp Penaeus vannamei (Crustacea Decapoda).—Experientia 51: 159– 163. + +Zwilling, R., H. Doersam, H. Torff, and J. Rold. 1981. Low molecular mass protease: evidence for a new family of proteolytic enzymes.—Federation of European Biochemical Societies Letters 127: 75–78. + +RECEIVED: 7 April 2003. ACCEPTED: 5 November 2003. diff --git a/outputs/multi_column/0a7e813e2010ecd8239725c32c859fe00c92_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0a7e813e2010ecd8239725c32c859fe00c92_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..36a231badc1504b1073d89c811bc5d90110aa47d --- /dev/null +++ b/outputs/multi_column/0a7e813e2010ecd8239725c32c859fe00c92_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,19 @@ +![](figure) + +![](figure) + +Henrik lbsen: Kad se mi mrtvi probudimo, DK Gavella, 1983. + +Duška Roksandića koji je tada bio intendant HNK-a. Ja sam igrala gospođicu Azru, animir-damu u jednoj raketnoj bazi, koja ima bliske susrete sa starim generalom Nottom u interpretaciji Zvonimira Rogoza. Tim je prizorom i počinjao komad. Scena je bila prazna, samo jedan pano s otvorenim prozorom. Mi smo stajali iza tog prozora i bili omeđeni prozorskim okvirom kao da smo ukadrirani u prvi plan nekog filma. Silno sam se veselila toj maloj ulogici koju sam htjela skicirati tijelom, zavodnički, pomalo imitirajući Merlinku. Potrebne su mi bile samo uska suknja i visoke potpetice. Međutim, kostim mi je izgledao sasvim suprotno: crvena haljinica s bijelim točkama, nabrana struka, a kad sam to obukla na sebe izgledala sam kao djevojčica. Obratila sam se Paru, zamolila ga da promijenimo kostim, što uopće nije bio problem, ali on je za dva dana došao s tvrdnjom da je saznao kako sam upravo ja zahtijevala takav kostim. Bilo mi je deplasirano istraživati gdje je nastao problem, je li se radilo o nečijoj sujeti ili lijenosti, ali ono što mi se čini najvjerojatnijim bila je indolencija koja nas stalno prati i vuče prema dolje. Mene je jako začudilo da jedan mladi redatelj nije imao sluha za potrebe glumice. To je bilo moje razočaranje. Tada, u tim mladim danima, na samom početku, Paro je još bio jako zatvoren. Ja sam ga osjećala kao ratio, kao čisti ratio koji planira svoju predstavu i radi je prema tome svom planu. Ali između mene na sceni i njega u gledalištu za vrijeme proba bio je ponor – hladno, hladno, hladno! Nažalost, to su bile moje prve impresije s njim. Još nismo bili zreli ni on ni ja, ni životno ni profesionalno. Poslije smo se sreli u Heretiku[^2]. Ja sam bila sretna da sam igrala jedno od troje protagonista koji su se slobodno kretali po sceni jer ta njegova scenografska inovacija, koja je možda bila praktična i zanimljiva, za glumce je bila katastrofa. Ti jadni ljudi morali su cijelu predstavu odstajati na triptihu, usko omeđeni u svojim nišama. Nisu se mogli ni pokrenuti, ni gestikulirati, čak nisu vidjeli ni partnera s kojim su komunicirali. Meni ih je bilo užasno žao. A onda se jedanput dogodila iznimno komična situacija: potkraj prvog čina, za vrijeme dramske pauze, najedanput smo čuli hrkanje: vatrogasac je zaspao gore na mostu. A ovi ljudi u triptihu – oni su jedva izdržali da ne eksplodiraju od smijeha. Triptih se počeo tresti, mislila sam da će se srušiti na nas, no na svu sreću brzo se spustio zastor. Na toj sam predstavi imala osjećaj da me Paro prevario. Zašto? Komad je morao na brzinu biti gotov zbog dogovorena termina za Sterijino pozorje, Žorž nas je izaranžirao na sceni i nestao – otišao je raditi u Prištinu i ostavio nas mladoj asistentici – Ivici Boban. Ponavljali smo domaću zadaću svakoga dana, a kad se vratio, ja sam se osjećala uvrijeđeno: ne ide to tako. + +Radili smo zajedno i na Dubrovačkim ljetnim igrama – recital stare dubrovačke poezije pod naslovom Pjesni razlike. Bila je to ponoćna serenada u Sponzi, dobili smo jako dobru ocjenu kritike. Uživala sam u tom poslu. + +A u teatru smo se sreli još samo jedanput kada smo radi-li posljednji Ibsenov komad Kad se mi mrtvi probudimo[^3]. Tamo sam igrala Maju Rubek, ženu slavnog umjetnika, ali starca. A ona je putena žena, razdire je njezino tijelo. Veselila sam se kako ću igrati nemir toga njezina tijela, a kad sam došla na probu kostima obukli su na mene debeli tamnosivi štof, zatvoren do grla. To je bilo tako teško da sam imala osjećaj kao da me netko ukopao 2-3 centime-tra u zemlju – nisam znala kako ću sada igrati s tim tijelom. Probala sam se sa Žoržom dogovoriti da nešto promijenimo. On me je blijedo gledao, uopće nije razumio o čemu ja govorim, pitao me Zar se ti možda bojiš da ćeš u tom debelom štofu izgledati deblje? A to za tu Maju Rubek uopće ne bi bilo negativno jer ona nije mlada djevojčica već putena žena. Tada nisam mogla izdržati. Rekla sam mu da ništa ne držim do teatra u kojem redatelj režira za sebe... No to su bili njegovi počeci kada on nije još nije bio onaj redatelj o kakvom se govori na ovom simpoziju, a što sam primjerice vidjela i u izvrsnom dokumentarcu Lade Džidić u prizorima kada je režirao Kolumba i kada je izgarao na probama. Ja nažalost takva Žorža ne poznajem. Njegov odgovor me zapanjio. Rekao je da on glumca žali i da on nikada ne bi mogao biti glumac jer mi moramo iz večeri u večer igrati jednu te istu predstavu, kao da nije znao da predstava tek nakon premijere započinje svoj život. I da ne postoje dvije identične predstave jer je publika taj faktor koji će diktirati puls predstave, gustoću i veličinu te interakcije koja je neopisiva kad se dogodi. + +Nažalost, to su moja jedina sjećanja na rad s Georgijem Parom. + +Poslije je došlo doba zrelosti; došle su njegove sjajne predstave od kojih sam imala priliku vidjeti i ove dvije dubrovačke, Areteja i Kolumba, zatim grandiozne Zastave koje su na sjajan način korespondirale s vremenom. To je bio nastavak njegova dugogodišnjeg bavljenja Krležom i rad kojemu se zaista divim. I poželjela sam da se u tome našem zrelijem dobu opet sretnemo u kazalištu. Bila sam uvjerena da bismo zajedno mogli nešto dobro napraviti. I pružila se prilika. Paru je bilo ponuđeno da dođe za umjetničkog ravnatelja u Dramsko kazalište Gavella. On je to s radošću prihvatio i mi smo bili vrlo sretni, imao je velike planove. Počeli smo s probama Genetovih Paravana. Imao je ideju da odvede predstavu tijekom pauze u susjedni restoran u Frankopanskoj koji danas više ne postoji. Predstava je trebala trajati pet sati – mi smo ga gledali, a on je rekao Pa to se tako danas u svijetu radi! Bili smo oduševljeni, bila je to tako pozitivna atmosfera, jedan entuzijazam, da bi onda probe bile naglo prekinute jer je politika odlučila drukčije – on je bio postavljen za intendanta HNK-a, a nama je došao Petar Veček iz Varaždina. I tako smo se u kreativnom smislu Žorž i ja nažalost mimoišli. + +[^2]: Heretik Ivana Supeka imao je praizvedbu u ZDK-u 28. II. 1969., a do listopada 1970. kada je skinut s repertoara odigran je 38 puta. Scenograf je bio Miše Račić, kostimografkinja Inge Kostinčer. U podjeli se našao gotovo cijeli ansambl kazališta na čelu s Božidarom Bobanom u ulozi Marka Antonija de Dominisa, a Ljubica Jović igrala je ulogu Sestre Fides. + +[^3]: Predstava je imala premijeru 17. IX. 1983., a do 15. I. 1985. kada je skinuta s repertoara odigrano je 26 izvedbi. Scenografi su bili Josip Vaništa i Ante Vulin, kostimograf Zlatko Bourek, sklada- telj Neven Frangeš. Ostale uloge igrali su Drago Krča (Arnold Rubek), Marino Matota, Stevo Krnjajić, Biserka Ipša i Ljiljana Gener. diff --git a/outputs/multi_column/0ad649e2f8ae7693c5cebe066451b7c22dc2_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/0ad649e2f8ae7693c5cebe066451b7c22dc2_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..28ab449319e021936a30252e2a2d9e55abbee419 --- /dev/null +++ b/outputs/multi_column/0ad649e2f8ae7693c5cebe066451b7c22dc2_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,33 @@ +![](figure) + +Figure 4 Percentage of green fluorescent protein (GFP) positive hepatocytes (Hcs) one month after GFP positive bone marrow derived cell (BMDC) transplantation, as a function of the number of infused cells (group F; n = 8). + +three bands (511, 67, and 12 bp, the last one not visible). In Gunn j/j rats, which received infusion of BMDCs from nonaffected, wild type animals, four bands are visible, including those derived from digestion of the normal enzyme. + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +● There has been much interest in cell therapy for liver metabolic ● disorders in the last decade, and several investigators have reported a significant clinical improvement following hepatocyte transplantation as an alternative to liver transplantation.9 Major limitations are the limited availability of human hepatocytes and the limited long term efficacy. In theory, the use of BMDCs as an alternative to hepatocytes could solve both problems. The present work indicates first, that a significant parenchymal repopulation with hepatocyte-like cells derived from BMDCs can be induced even in metabolic disorders not associated with increased parenchymal cell turnover; second, that probably such repopulation is mostly due to differentiation rather than to cell fusion; and third, that such repopulation results in partial correction of a congenital hepatic metabolic disorder. The extent of parenchymal repopulation with exogenous bone marrow derived, GFP positive hepatocyte-like cells averaged 0.4% in the liver lobes submitted to I/R 72 hours after infusion, but it increased by more than 20-fold after one month, suggesting proliferation of the exogenous cells. The histological finding showing large clusters of GFP positive hepatocytes supports this hypothesis. Continuous propagation of stem/progenitor cells in the absence of ongoing liver damage can be driven by cell–cell competition, with increased proliferation and reduced apoptosis of the transplanted cells when + +![](figure) + +Figure 5 Bone marrow derived cells (BMDCs) isolated from green fluorescent protein (GFP) positive transgenic rats acquire morphological features and phenotypic markers of differentiated hepatocytes after transplantation into liver injured Lewis recipients (group F). Serial sections of livers removed four weeks after cell transplantation were stained for GFP (A) and for CK-18 (B). (C–E) Extensive repopulation of liver parenchyma with GFP positive hepatocytelike cells four weeks after transplantation of 106106 GFP positive BMDCs (group F). Large clusters of GFP positive hepatocyte-like cells are mainly located in proximity of blood vessels. (F) GFP positive endothelial-like cells (arrows) are also visible in the ischaemic lobes. (Original magnification: (A), (B) 620; (C), (D), (E) 610; (F) 640.) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) diff --git a/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_12_pg1_pg1_repeat1.md b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_12_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..252fe5774325c3de6755c04dfe1b4787a06a63cf --- /dev/null +++ b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_12_pg1_pg1_repeat1.md @@ -0,0 +1,25 @@ +# Mandela Commemoration Medal Parade + +## By Cpl Ally Rakoma Photos by S Sgt Lebogang Tlhaole + +It has been a year since the passing of the founding President of a democratic South Africa, the first Commander-in-Chief of the SANDF and Nobel Peace Prize recipient, the late Mr Nelson Mandela. + +In line with our country’s activities to commemorate the first anniversary of Tata Mandela’s death, the SANDF held a Mandela Commemorative Medal Parade at Air Force Base Waterkloof in Pretoria last month. + +President Jacob Zuma, the President of South Africa and Commander-in-Chief of the SANDF, was the main functionary at the medal parade. He awarded gold medals to SANDF men and women for their role in taking care of our statesman during the period when he was ill, his funeral, the mourning period arrangements, the lying-in-state at the Union Buildings and leading the state funeral at Qunu. + +President Zuma expressed his gratitude and admiration to the SANDF for carrying out its duties towards its first Commander-in-Chief. President Zuma said: “I can say with pride that the planning, execution and precision with which the SA National Defence Force (SANDF) performed its duties left no one in doubt about the capability of our armed forces.” + +![](figure) + +![](figure) + +He also thanked the international community for standing by South Africa as the world mourned the former statesman’s death on 5 December 2013. President Zuma said: “We remain grateful for this support + +LEFT: President Jacob Zuma, the President of South Africa and Commanderin-Chief of the SANDF, addresses the parade accompanied by the Minister of Defence and Military Veterans, Ms Nosiviwe Mapisa-Nqakula, and Lt Gen Norman Yengeni, the Chief of Human Resources. + +![](figure) + +![](figure) + +ABOVE: Fltr: Mr Siphiwe Dlamini, Head of Communication, Prof Edna van Harte, the Chairperson of the Defence Force Service Commission, Adv George Bizos, Veteran Human Rights Lawyer and Madiba’s close friend, Justice Dikgang Moseneke, the Deputy Chief Justice of the Constitutional Court of South Africa, Dr Sam Gulube, Secretary for Defence, and Mr Kebby Maphatsoe, the Deputy Minister of Defence and Military Veterans, at the Mandela Commemoration Medal Parade. diff --git a/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_18_pg1_pg1_repeat1.md b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_18_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e62027c36610e40a2b56436141c400ee944ccf3b --- /dev/null +++ b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_18_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +# The National Civic Remembrance Sunday and Wreath-laying ceremony + +##### By Cpl Ally Rakoma Photos by Sgt Elias Mahuma + +ANational Civic Remembrance Service and a wreath-laying ceremony were held at the Cenotaph in Harrison Street, Johannesburg to pay tribute to and commemorate the South African soldiers who perished during World War I. The theme was: “Unification and Nation Building”. + +The 2014 Commemoration marked the 100th anniversary of the start of World War I (1914-1918), the war that claimed the lives of 12 452 South African soldiers. The commemoration in Johannesburg is the largest of its kind in South Africa, + +![](figure) + +![](figure) + +ABOVE: Councillor Parks Tau, the Executive Mayor of the City of Johannesburg, laying a wreath. + +![](figure) + +![](figure) + +ABOVE: Maj Gen Michael Ramantswana, Chief Military Policy, Strategy and Planning, laid a wreath on behalf of the Chief of the SANDF, Gen Solly Shoke. + +and links with Remembrance Day events held in many cities around the world. It is held annually on the Sunday nearest to 11 November (Armistice Day). + +The Executive Mayor of the City of Johannesburg, Councillor Parks Tau, accompanied by senior SANDF diff --git a/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_20_pg1_pg1_repeat1.md b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_20_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..8df17270ecca2f854298e15d290b9d4782f3b1c2 --- /dev/null +++ b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_20_pg1_pg1_repeat1.md @@ -0,0 +1,27 @@ +# SA Army observes the 96th anniversary of Armistice Day + +By CO Marumo Machete, SO3 External Communication SA Army Photos by Lance Bombardier Refilwe Sebopa + +Memories of Armistice Day of 96 years ago were relived at the SA Army Headquarters in Pretoria as the Chief of the SA Army, Lt Gen Vusi Masondo, led the SA Army in marking International Remembrance Day. + +Continuing a commemorative tradition that spans more than nine decades, a salvo from the Artillery’s G1 gun opened the proceedings with a deafening bang for the sombre remembrance of the survivors and those that laid down their lives during the war that lasted four years from 1914 until the armistice in 1918. + +A two-minute silence was observed, a minute for the survivors of the carnage of World War I and another for those who paid the ultimate sacrifice and perished during the war. This culminated in the last salvo fired by the G1 gun. + +![](figure) + +![](figure) + +The Chief of the SA Army laid a wreath at the memorial on the lawns of the SA Army Headquarters complex before delivering his tribute. + +Addressing the Army Council and the Generals and spectators in attendance, Lt Gen Masondo urged those in attendance never to take for granted the selfless sacrifices made by those who were involved in the war. + +Lt Gen Masondo said: “As the SA Army marches into its third decade of defending our democracy, let us join the world as it pauses to reflect + +ABOVE: Lt Gen Vusi Masondo, the Chief of the SA Army, laid a wreath at the memorial on the lawns of the SA Army Headquarters complex before delivering his tribute. + +and remember the warriors of the Great War.” + +He continued: “Let us honour their sacrifice and strive for a peaceful world where no innocent blood will have to be spilled, as there are so many forms of recourse to avert war and prevent conflict from escalating.” He also paid homage to the South African soldiers who died pursuing peace and stability on the African continent following the country’s post-1994 readmission to the international community. + +In assessing the salient issues facing our country, the Chief of the SA Army took the opportunity to acknowledge the great contribution diff --git a/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_26_pg1_pg1_repeat1.md b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_26_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ada45c446639575b2526156db3df55813daf768c --- /dev/null +++ b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_26_pg1_pg1_repeat1.md @@ -0,0 +1,27 @@ +### events + +# Chief Human Resources honours his loyal members + +By Ms Thuli Ntuli, Intern SA Soldier Photos by L Cpl Jonathan Mogano + +The Chief Human Resources, Lt Gen Norman Yengeni, recently held his Medal Parade in which he awarded deserving members of the Human Resources Division for rendering outstanding and loyal service. + +Altogether 118 medals and certificates were awarded to both the uniformed and civilian members of the Human Resources Division at the medal parade held at the Personnel Services School in Thaba Tshwane. + +Lt Gen Yengeni conferred nine different awards, namely the Tshumelo Ikatelaho, followed by the Good Service Medal Silver (20 Years), the Bar to the Medalje vir Troue Diens - 20 Years (After 27 April 2003), the Bar to the Medalje vir Troue Diens (20 Years), the Good Service Medal Bronze (10 Years), the Faithful Service Medal (Transkei: 10 Years), the MK (10 Years), the Medalje vir Troue Diens (10 Years) and certificates (30 Years) for civilian personnel. Lt Gen Yengeni said that it was military tradition to honour those members who had excelled in the SA National Defence Force (SANDF) through outstanding acts of valour. + +Congratulating the recipients, Lt Gen Yengeni said: “Each medal and certificate tells a story of its own. It is a narrative of dedication and sacrifice granting the bearer recognition and value for their service. You deserve these medals! Wear them with pride! Your determination to make a difference has paid off.” + +![](figure) + +![](figure) + +He also extended his salutations to the partners and families of the awarded recipients. The Chief of Human Resources also highlighted the + +Left: Lt Gen Norman Yengeni, Chief Human Resources, addressing the members attending the Medal Parade at Personnel Services School in Thaba Tshwane. + +![](figure) + +![](figure) + +ABOVE: The National Ceremonial Guard marching at the Human Resources Division Medal Parade. diff --git a/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_27_pg1_pg1_repeat1.md b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_27_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9e83fd25bd8d3080098092eb1414c9fc071f818e --- /dev/null +++ b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_27_pg1_pg1_repeat1.md @@ -0,0 +1,27 @@ +LEFT: Lt Gen Norman Yengeni, Chief Human Resources, awarding the Bar to the Medalje vir Troue Diens for 20 Years to Lt Col Riaan Nel. + +![](figure) + +![](figure) + +performance of the Division during the 2014/15 Financial Year. + +![](figure) + +![](figure) + +ABOVE: Some of the Human Resources Division members who received medals for rendering outstanding services. + +Lt Gen Yengeni said some courses and workshops were started and some were continuing. These included the 180 officers commanding and line managers who attended six labour relations workshops in the Department of Defence (DOD), training for the Human Resources’ planners, the School of Military Justices’ first Law of Armed Conflict (LOAC) Trainer of Trainers’ Course and the two-stream qualification of M Phil in Security and Defence Studies Programme. + +The Chief Human Resources alerted the DOD members about the salary adjustment of 1.5 per cent. He also said that a new concept model was under way; this model will address the redeployment and employment of SANDF members who have reached the brink of their careers. + +He added that the coordination of the Auditor-General’s queries was progressing fairly well as 90 per cent of the information had already been submitted to the Auditors. + +Lt Gen Yengeni congratulated Chief Directorate Transformation + +Management on hosting a successful 2014 Casual Day event in which R72 000 was raised. These funds will be utilised by Curamus to cater for the special needs of soldiers living with disabilities. + +The Chief Human Resources vowed to stay on top of further progress and its implementation during the course of the 2015/2016 Financial Year. He said: “The Department will move with speed in the second quarter to ensure the full implementation of these resolutions.” + +✗ diff --git a/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..07af402c24af79e57759f420d07f7ee176c9e5b4 --- /dev/null +++ b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,119 @@ +# SA SOLDIER + +#### The official monthly magazine of the SA Department of Defence + +| 4 | From the Editor’s desk | +| --- | --- | +| 5 | End of an era for the Executive National | +| | Security Programme | +| 6 | Letters to the editor | +| 10 | South Africa assists | +| | Mozambique Government during the floods | +| 12 | Mandela | +| | Commemoration | +| | Medal Parade | +| 16 | Chief SANDF bestows medals for first-class service to the SANDF | +| | 18 | +| 18 | National Civic | +| | Remembrance Sunday and Wreath-laying | +| | Ceremony | +| 20 | SA Army observes the 96th anniversary of Armistice Day | +| | STREET ADDRESS | + +![](figure) + +![](figure) + +Defence Headquarters cor Nossob & Boeing St Erasmuskloof PRETORIA + +##### POSTAL ADDRESS + +SA SOLDIER Private Bag X158 PRETORIA, 0001 + +##### TELEPHONE + +22 + +Future Armour Capability Conference + +24 + +Training Command bids farewell to its General Officer Commanding + +![](figure) + +![](figure) + +Graduation ceremony of the Joint Senior Command and Staff Programme + +25 + +Chief Human Resources honours his loyal members + +26 + +28 + +7th Warrant Officers’ Academy Certificate Ceremony + +29 + +30 + +32 + +Military Academy awarded its students who excelled + +Mitchells Plain Festival + +Preparing SA youth for a nautical career + +##### CONTRIBUTIONS: + +Although all possible care is taken with articles, the editorial staff cannot accept any responsibility for lost articles and photographs. + +Formeset Print (Pty) Ltd + +## 24 Kinghall Avenue + +Tel: (021) 507 9000 Fax: (021) 506 9092 + +| 34 | A visit to Air Force Base | +| --- | --- | +| | Ysterplaat Museum | +| | Retire or resign with | +| 36 | GEPF: What you need to know | +| | 39 | +| 39 | Johannesburg | +| | Regiments Association exercises its Freedom of Entry in Soweto | +| 40 | The DOD participates in Chief SANDF | +| | Prestige Week | +| 42 | Diseases of lifestyle pose a threat to the development of SA | +| 43 | Embracing our colleagues with disabilities | +| | REPRODUCTION, PRINTING & DISTRIBUTION: | +| EPPINGDUST, Cape Town, 7460 | | +| email: formeset@formeset.co.za | | + +2005 - Winner of the Government Communicator of the Year Award (GCIS). 2005 - Winner of the National Ubungcweti Award (GCIS). + +##### EDITORIAL STAFF + +Editor: + +Ms Nelda Pienaar + +Deputy Editor: Mr Lufuno Netshirembe + +Editorial Staff: S Sgt Lebogang Tlhaole Sgt Itumeleng Makhubela Cpl Ally Rakoma + +Translation Consultant: + +Directorate Language Services + +Distribution: + +Mr Jim Tshabalala Tel: (012) 355 6341 + +Layout & Design: + +Mr Werner van der Westhuizen diff --git a/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_30_pg1_pg1_repeat1.md b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_30_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..204870efa6d5a061dc2a6c894a93339bf16f42a1 --- /dev/null +++ b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_30_pg1_pg1_repeat1.md @@ -0,0 +1,27 @@ +### events + +# Mitchells Plain Festival + +##### Article and photos AB Sello Matloga, journalist at Navy News + +Mitchells Plain Festival is an annual spectacular fun-filled family event where the SA National Defence Force (SANDF) gets an opportunity to display its hardware and inform the public about its mandate. + +This annual event was packed with a wide variety of activities for the whole family, including food stalls + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +and information centres. The first day took off with military displays by 9 SA Infantry Battalion (SA Army) demonstrating counter-attack tactics with smoke grenades and rifle shooting to the amazement of the learners from the surrounding primary schools. Members of the SA Navy Dog Unit displayed the agility and tactics of their well trained dogs while the SA Navy Precision Drill Squad captivated the public with their quick moves. The Lynx helicopter of the SA Navy on display was a show stopper + +- a definite favourite for many curious families. The public was amazed by the fire power of the SA Army, which had weapons and tanks on display. Most young people and parents were interested in the SIYANDIZA Programme of the SA Air Force. SIYANDIZA aims to develop learners through the orientation programmes of the SA Air Force and draws special attention to possible careers in aviation. The Human Resources Section offered information on careers in the SANDF which included specialised avionics, combat, engineering, maritime, technical, + +ABOVE: The Lynx helicopter of the SA Navy on display was a show stopper - a definite favourite for many curious families. + +LEFT: Curious little minds visiting the information stall of the SANDF. + +military health occupations and electronics. Informative materials were on display as part of the recruitment drive that aimed to rejuvenate the organisation with educated and fit young patriots. One of the parents at the Mitchells Plain Festival, Ms Melisa Sergrys, said: “I had so much fun today, my boys loved all the military vehicles and the air show was my favourite. Thank you so much for an awesome vibe. It was my first time and I will definitely not miss it ever again”. diff --git a/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_32_pg1_pg1_repeat1.md b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_32_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ac8a6b3ce2a3a2aa5f9ec3017163c1ef97341ec0 --- /dev/null +++ b/outputs/multi_column/0b045ab838c05c4ff1ac844caf826f8f368d_page_32_pg1_pg1_repeat1.md @@ -0,0 +1,31 @@ +# Preparing South African youth for a nautical career + +##### Article and photos by Lt Cdr Glenn von Zeil, SA Naval Reserves + +The motto “Honour and Skill” of the South African Sea Cadets is proudly displayed under their badge. These words embody the core values of the Corps which are: Integrity, excellence and service, which are instilled in the Sea Cadets via their training and interaction with competent instructors. These three words embody the cardinal points of a Sea Cadet’s compass of life and include: Honesty, morality, loyalty, responsibility, discipline, accountability, self-respect and obedience. The Sea Cadets also teach the necessary knowledge and provides practical skills underwritten by accredited courses necessary for those who wish to follow a career at sea within the maritime industry. + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +The Sea Cadet in South Africa movement traces its origins back to the first South African Training Ship (TS), located on Woodstock beach Cape Town, TS Woltemade was opened on + +## 8 June 1905. The movement spread + +throughout South Africa and currently there are 15 training ships, nine are active and developing those values and skills required to ensure that the maritime industry is provided with recruits who have a passion for the sea. + +### Who are the Sea Cadets? + +Sea Cadets are school going boys and girls from Grade 6 to Grade 12 who enjoy having “serious fun” while learning leadership, self-discipline and maritime orientated skills as a voluntary extra mural activity. Any youngster irrespective of race, gender or religion is welcome. + +ABOVE: Sea Cadets practicing “pulling” which forges teamwork. + +LEFT: Sea Cadets undergoing survival at sea training while on an annual year end camp at the SA Navy’s Seamanship School at SAS SIMONSBERG. + +### Where and when does the training take place? + +The land based training ships located around the country provide a safe space with competent instructors at which training can take place. Training takes place on Fridays or Saturdays or Sundays depending on the training ship involved, with leadership camps scheduled during the school holidays. The highlight of the year is the annual camp hosted by the SA Navy in Simon’s Town. diff --git a/outputs/multi_column/0b128decb905a38700baf486672b8634c308_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0b128decb905a38700baf486672b8634c308_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..718895037c820f5e8a06accd6510e32ed8f5abe4 --- /dev/null +++ b/outputs/multi_column/0b128decb905a38700baf486672b8634c308_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,26 @@ +# Effect of Treatment With SB 242784 on Soft Tissue Calcification in Rats Treated With Vitamin D + +| Tissue, mmol | Vitamin D Only | Vitamin D110 mg SB 242784 | Vitamin D140 mg SB 242784 | Age-Matched Control | +| --- | --- | --- | --- | --- | +| Abdominal aorta | 3.161.3 | 1.460.5* | 0.360.03† | 0.360.02 | +| Kidney | 39.6632.5 | 20.7611.9 | 2.660.2‡ | 1.160.2 | +| Lungs | 95.5624.3 | 26.7633.6 | 3.860.3§ | 3.460.5 | +| Trachea | 2.060.2 | 1.960.3 | 0.960.7i | 0.660.2 | + +Seven-week-old male rats received subcutaneous injections of 500¦000 IU of vitamin D/kg body wt at \(t50,24\), and 48 hours. Subsets of these animals were also injected with either 10 or 40 mg SB 242784/kg body wt per day beginning at 2 days before the first injection of vitamin D. Animals were killed 96 hours after the first vitamin D injection, and the abdominal aorta, one kidney, the lungs, and an anatomically uniform 1 cm of trachea were ashed (see Materials and Methods for further details). The ashed tissues were extracted with acid to dissolve minerals, and each acid extract was analyzed for calcium as described in Materials and Methods. Results are given as \(m\)mol calcium in the indicated tissue. Vitamin D treatment does not result in any significant increase in the size or wet weight of the tissues analyzed. Therefore, the increase in calcium content seen in the tissues from the vitamin D treatment group cannot be due to changes in the size or mass of the tissues (authors’ unpublished observations, 2002). Data are mean\(6SD,n54\), for all groups. + +\(*P50.06\) compared with vitamin D only. \(\dagger P50.005\) compared with vitamin D only. \(\ddagger P50.063\) compared with vitamin D only. \(§P50.0003\) compared with vitamin D only. \(iP50.023\) compared with vitamin D only. + +control animals (Table). Calcium levels measured on serum obtained 96 hours after the first vitamin D injection were as follows: \(13.461.2\) mg/dL for rats treated with vitamin D only \((n54),14.060.9\) mg/dL for rats treated with vitamin D plus the 10-mg dose of SB \(242784(n54)(P.0.5\) versus vitamin D alone), \(10.860.5\) mg/dL for rats treated with vitamin D plus the 40-mg dose of SB \(242784(n54)(P,0.01\) versus vitamin D alone), and \(10.960.3\) mg/dL for untreated control rats \((n54)(P,0.001\) versus vitamin D alone). To confirm that SB 242784 did in fact inhibit bone resorption at the doses used in the above experiments, serum samples obtained at death were analyzed to determine the level of cross-linked N-teleopeptides, a specific marker for bone resorption activity that is released during the osteoclastmediated breakdown of bone matrix collagen. As seen in Figure 4, the level of cross-linked N-teleopeptides was elevated by 140% in rats treated with vitamin D alone and was reduced to below control levels in rats treated with vitamin D plus the higher dose of SB 242784. This result supports the hypothesis that vitamin D treatment induces arterial calcification by accelerating bone resorption and shows that SB 242784 treatment dose-dependently inhibits bone resorption activity in the vitamin D–treated rat. The effect of SB 242784 on arterial calcification was also examined in rats treated with warfarin, a treatment that inactivates the calcification-inhibitory activity of matrix Gla protein and thereby induces rapid calcification of arteries and cartilage. In the first experiment, weanling rats were treated for 1 week with warfarin alone or with warfarin plus 10 mg SB 242784/kg per day. This experiment showed that the 10-mg dose of SB 242784 did not significantly inhibit arterial calcification as assessed by alizarin red staining. Subsequent analysis of bone resorption activity using the cross-linked N-teleopeptide assay showed that the 10-mg dose of SB 242784 also did not significantly reduce bone resorption activity in the warfarin-treated rats. When this experiment was repeated at the higher dose (40 mg/kg per day) of SB 242784, we observed that the drug strongly inhibited arterial + +![](figure) + +![Bar graph showing Serum Cross Linked N-teleopeptides, µg/L for Control, Vitamin D only, Vitamin D + 10mg SB242784, and Vitamin D + 40 mg SB242784. The y-axis is labeled 'Serum Cross Linked N-teleopeptides, µg/L' and ranges from 0 to 180. The x-axis lists the groups: Control, Vitamin D only, Vitamin D + 10mg SB242784, and Vitamin D + 40 mg SB242784. There are error bars above each bar, and letters a, b, and c indicate statistical significance between groups.](figure)[^inferred] + +![Bar graph showing Serum Cross Linked N-teleopeptides, µg/L for Control, Vitamin D only, Vitamin D + 10mg SB242784, and Vitamin D + 40 mg SB242784. The y-axis is labeled 'Serum Cross Linked N-teleopeptides, µg/L' and ranges from 0 to 180. The x-axis lists the groups: Control, Vitamin D only, Vitamin D + 10mg SB242784, and Vitamin D + 40 mg SB242784. There are error bars above each bar, and letters a, b, and c indicate statistical significance between groups.](figure)[^inferred] + +![](figure) + +Figure 4. Effect of SB 242784 on bone resorption activity as measured by serum cross-linked N-teleopeptides. Serum was obtained from each animal 96 hours after the first vitamin D injection in the experiment described in the Figure 1 legend, and serum was also obtained from 4 age-matched control rats. Each serum sample was analyzed to determine the level of cross-linked N-teleopeptides (OSTEOMARK NTx, Ostex), a specific marker for bone resorption activity (see Materials and Methods). Results are presented as mean\(6SD\). a, \(P,0.01\) compared with control; b, \(P,0.05\) compared with vitamin D only; and c, \(P,0.001\) compared with vitamin D only. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0b2e551bbc33b030f810311118e2088d7ae3_page_12_pg1_pg1_repeat1.md b/outputs/multi_column/0b2e551bbc33b030f810311118e2088d7ae3_page_12_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ec2fec0510400a8720ce8511f29140c85de0f052 --- /dev/null +++ b/outputs/multi_column/0b2e551bbc33b030f810311118e2088d7ae3_page_12_pg1_pg1_repeat1.md @@ -0,0 +1,55 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +inches behind the point in the downswing where the club was vertical. The height of the tee and the toe-heel position of the club relative to the tee were adjusted in order that the center of the impact mark was about \(\frac{3}{4}\) of an inch above the sole and was centered toe to heel across the face. Three samples of each ball were tested. Each ball was hit three times. + +Other methods may also be used to determine the scuff resistance, such as the methods described in the commonly assigned copending application titled "Golf Ball Wear Indicator", U.S. application Ser. No. 12/691,282, filed Jan. 21, 2010, in the name of Brad Tutmark. + +After the above described scuff resistance testing, each golf ball cover was visually observed and rated according to the following scale: a golf ball cover was rated "1" when little or no damage was visible, only groove markings or dents; a golf ball cover was rated "2" when small cuts and/or ripples in the cover were apparent; a golf ball cover was rated "3" when moderate amounts of cover material were lifted from the ball's surface, but the cover material was still attached to the ball; and finally a golf ball cover was rated "4" when cover material was removed or barely attached to the golf ball. + +Shore D hardness values of the core and cover layer were measured on the spherical surface of the layer to be measured by using a Shore D hardness tester. + +As shown in Table 5, golf ball examples 1 and 2 made from compositions including a cross-linked thermoplastic polyurethane elastomer having cross-links located in the hard segments, where the cross-links are the reaction product of unsaturated bonds located in the hard segments as catalyzed by a free radical initiator and a proper ratio of the organic isocyanate to the long chain polyol, provides superior scuff resistance. + +Additional golf balls are made in accordance with the method and comprising the compositions of Examples 1 and 2, with the exception that the index is 1.20 in one golf ball, 1.30 in another, and 1.40 in a third. The golf balls then are subjected to the scuffing test, and provide a scuff resistance rating of 1.5, 1.5, and 1. + +While various embodiments of the invention have been described, the description is intended to be exemplary, rather than limiting and it will be apparent to those of ordinary skill in the art that many more embodiments and implementations are possible that are within the scope of the invention. Accordingly, the invention is not to be restricted except in light of the attached claims and their equivalents. Also, various modifications and changes may be made within the scope of the attached claims. For example, different golf ball precursors, perhaps those having a different number of layers or a different core composition, also fall within the scope of the claims. + +We claim: + +1. A method of making a golf ball, comprising the steps of: forming a golf ball precursor, the precursor having at least one golf ball layer but not an outer cover layer and forming an outer cover layer substantially surrounding the golf ball precursor, wherein the outer cover layer comprises a composition of an over-indexed, crosslinked thermoplastic polyurethane elastomer including crosslinks formed from allyl groups and the thermoplastic polyurethane elastomer is a reaction product formed from reacting a mixture of a diisocyanate and: + +(a) an unsaturated diol of the formula + +\[\text{HO-} \begin{array}{c} \text{R}^1 \\ | \\ \text{C} \text{-(CH}_2\text{)}_x\text{-OH} \\ | \\ \text{R}^2 \end{array} \text{-OH}\] + +in which \(R^1\) is a substituted or unsubstituted alkyl group, substituted or unsubstituted aryl group, or substituted or unsubstituted alkyl-aryl group, which may optionally include an ether or ester group or an unsaturated bond in any group, or is H; \(R^2\) is a substituted or unsubstituted alkyl group, substituted or unsubstituted aryl group, or substituted or unsubstituted alkyl-aryl group, which may optionally include an ether or ester group, and \(R^2\) includes an allyl group; and x and y are integers independently having any value from 1 to 10; + +(b) a chain extender having at least two reaction sites with isocyanates and having a molecular weight of less than about 450; (c) a long chain polyol having a molecular weight of between about 500 and about 4,000; and (d) a sufficient amount of free radical initiator so as to be capable of generating free radicals that induce crosslinking structures in the hard segments by free radical initiation, + +wherein the mixture has a stoichiometric excess of isocyanate moieties of at least about 1 mol percent; + +wherein forming the outer cover layer further comprises applying the composition over the golf ball precursor and then moisture curing the composition; and + +wherein the outer cover layer has a flexural modulus between 400 psi and 900 psi. + +2. The method of making the golf ball according to claim 1, wherein the organic isocyanate moieties to the hydroxyl moieties are in a molar ratio of from about 1.06:1.00 to about 1.18:1.00. + +3. The method of making the golf ball according to claim 2, wherein the molar ratio is from about 1.10:1.00 to about 1.15:1.00. + +4. The method of making the golf ball according to claim 1, wherein the free radical initiator is present in the mixture in a weight ratio of free radical initiator to unsaturated diols of from about 0.1:100 to about 100:100. + +5. The method of making the golf ball according to claim 4, wherein a weight ratio of the crosslinked thermoplastic polyurethane elastomer to the unsaturated diols is about 100:10. + +6. The method of making the golf ball according to claim 1, wherein the unsaturated diol is trimethylolpropane monoallyl ether. + +7. The method of making the golf ball according to claim 1, wherein the free radical initiator generates free radicals through at least one of thermal cleavage and UV radiation cleavage. + +8. The method of making the golf ball according to claim 1, wherein the free radical initiator is selected from the group consisting of peroxides. + +9. The method of making the golf ball according to claim 1, wherein the step of forming a golf ball precursor further comprises the steps of: + +forming an inner core layer comprising a highly neutralized acid polymer; + +forming an outer core layer substantially surrounding the inner core layer; and + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0b2e551bbc33b030f810311118e2088d7ae3_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/0b2e551bbc33b030f810311118e2088d7ae3_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2e48b1a460caf6039fdc6bbce0d1fb89550ee228 --- /dev/null +++ b/outputs/multi_column/0b2e551bbc33b030f810311118e2088d7ae3_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,29 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +tralized acid polymer composition(s) of inner core layer 440 have Vicat softening temperatures of from 50° C. to 60° C. + +Suitable highly neutralized acid polymer compositions for use in forming inner core layer 440 may comprise a highly neutralized acid polymer composition and optionally additives, fillers, and/or melt flow modifiers. The acid polymer is neutralized to 70% or higher, including up to 100%, with a suitable cation source, such as magnesium, sodium, zinc, or potassium. + +Suitable additives and fillers include, for example, blowing and foaming agents, optical brighteners, coloring agents, fluorescent agents, whitening agents, UV absorbers, light stabilizers, defoaming agents, processing aids, mica, talc, nanofillers, antioxidants, stabilizers, softening agents, fragrance components, plasticizers, impact modifiers, acid copolymer wax, surfactants; inorganic fillers, such as zinc oxide, titanium dioxide, tin oxide, calcium oxide, magnesium oxide, barium sulfate, zinc sulfate, calcium carbonate, zinc carbonate, barium carbonate, mica, talc, clay, silica, lead silicate, and the like; high specific gravity metal powder fillers, such as tungsten powder, molybdenum powder, and the like; regrind, i.e., inner core material that is ground and recycled; and nanofillers. Suitable melt flow modifiers include, for example, fatty acids and salts thereof, polyamides, polyesters, polyacrylates, polyurethanes, polyethers, polyureas, polyhydric alcohols, and combinations thereof. + +Inner core layer 440 may be made by a fabrication method such as hot-press molding or injection molding. In embodiments of the disclosure, the diameter of inner core layer 440 may be in a range of about 21 millimeters to about 28 millimeters, or in a range of about 24 millimeters to about 28 millimeters. Inner core layer 440 may have a surface Shore D hardness of 45 to 55. Inner core layer 440 has a Shore D cross-sectional hardness of from 45 to 55 at any single point on a cross-section obtained by cutting inner core layer 440 in half, and has a Shore D cross-sectional hardness difference between any two points on the cross-section of within \(\pm 6\) . By controlling the Shore D hardness difference of inner core layer 440, the ball over-all performance may be stable. To have a lower ball spin rate, inner core layer 440 may have a compression deformation of from about 3.4 millimeters to about 4.2 millimeters. + +To protect thermoplastic inner core layer 440 during core-forming process, it is preferred that outer core layer 430 has a thickness of from 5 millimeters to 9 millimeters and has a volume which is greater than any other layers of golf ball 400. Outer core layer 430 typically has a surface Shore D hardness of between about 50 to about 60, and the hardness of the outer core layer is greater than the Shore D hardness of inner core layer 440. + +The material making up outer core layer 430 may be thermoset materials selected from the group consisting of polyurethane elastomer, polyamide elastomer, polyurea elastomer, diene-containing polymer (such as polybutadiene), cross-linked metallocene catalyzed polyolefin, silicone, and a mixture thereof. Outer core layer 430 may be made by cross-linking a polybutadiene rubber composition. When other rubber is used in combination with a polybutadiene, it is preferred that polybutadiene is included as a principal component. Specifically, a proportion of polybutadiene in the entire base rubber is preferably equal to or greater than about 50 percent by weight, and particularly preferably equal to or greater than about 80 percent by weight. A polybutadiene having a proportion of cis-1,4 bonds of equal to or greater than about 60 mol percent, and further, equal to or greater than about 80 mol percent, is preferred. + +In some embodiments, cis-1,4-polybutadiene may be used as the base rubber and mixed with other ingredients. In some embodiments, the amount of cis-1,4-polybutadiene may be at least about 50 parts by weight, based on 400 parts by weight of the rubber compound. Various additives may be added to the base rubber to form a compound. The additives may include a cross-linking agent and a filler. In some embodiments, the cross-linking agent may be zinc diacrylate, magnesium acrylate, zinc methacrylate, or magnesium methacrylate. In some embodiments, zinc diacrylate may provide advantageous resilience properties. The filler may be used to increase the specific gravity of the material. The filler may include zinc oxide, barium sulfate, calcium carbonate, or magnesium carbonate. In some embodiments, zinc oxide may be selected for its advantageous properties. Metal powder, such as tungsten, may alternatively be used as a filler to achieve a desired specific gravity. In some embodiments, the specific gravity of outer core layer 430 may be from about 1.05 g/cm\(^3\) to about 1.25 g/cm\(^3\) . Further, outer core layer 430 may have a surface Shore D hardness of from about 30 to about 75. + +In some embodiments, a polybutadiene synthesized using a rare earth element catalyst is preferred. By using this polybutadiene, excellent resilience performance of golf ball 400 can be achieved. Examples of rare earth element catalysts include lanthanum series rare earth element compound, organoaluminum compound, and alumoxane and halogen containing compound. A lanthanum series rare earth element compound is preferred. Polybutadiene obtained by using lanthanum rare earth-based catalysts usually employ a combination of lanthanum rare earth (atomic number of 57 to 71) compounds, but particularly preferred is a neodymium compound. + +Outer core layer 430 is preferably made by hot-press molding process. Suitable vulcanization conditions include a vulcanization temperature of between 130° C. and 190° C. and a vulcanization time of between 5 and 20 minutes. To obtain the desired rubber cross-linked body for use as the core in the present invention, the vulcanizing temperature is preferably at least 140° C. + +When outer core layer 430 of the present invention is produced by vulcanizing and curing the rubber composition in the above-described way, advantageous use may be made of a method in which the vulcanization step is divided into two stages. The outer core layer material is placed in an outer core layer-forming mold and subjected to initial vulcanization so as to produce a pair of semi-vulcanized hemispherical cups, and then a prefabricated inner core layer is placed in one of the hemispherical cups and is covered by the other hemispherical cup, in which state complete vulcanization is carried out. + +The surface of inner core layer 440 placed in the hemispherical cups may be roughened before the placement to increase adhesion between inner core layer 440 and outer core layer 430. In some embodiments, inner core layer surface is pre-coated with an adhesive or pre-treated with chemical(s) before placing inner core layer 440 in the hemispherical cups to enhance the durability of the golf ball and enable a high rebound. + +Alternatively, the inner core layer may comprise the afore-mentioned thermoset material while the outer core layer may comprise the thermoplastic material, or any combination thereof. + +In embodiments where the core construction is multilayered, the COR of the inner core layer, such as inner core layer 440 in FIG. 1, at forty (40) meters per second may be from about 0.78 to about 0.92, and may be higher than that of the + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0b65b6a5c9e4533f7c7859dcbb1eede86907_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0b65b6a5c9e4533f7c7859dcbb1eede86907_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e03fa2c609568a5dd74a0a0b2231a2a1dc0a0ae8 --- /dev/null +++ b/outputs/multi_column/0b65b6a5c9e4533f7c7859dcbb1eede86907_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,175 @@ +3. Lobo RA, Kletzky OA, Campeau JD & diZerega GS, Elevated + +bioactive luteinizing hormone in women with the polycystic + +ovary syndrome. Fertil Steril, 1983; 39: 674-8. + +4. Polson DW, Adams J, Wadsworth J & Franks S, Polycystic + +ovaries Ð a common finding in normal women. Lancet, 1988; 1: + +870-2. + +5. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. + +Fertil Steril, 2004; 81: 19-25. + +6. Azziz R, Controversy in clinical endocrinology: diagnosis of polycystic ovarian syndrome: the Rotterdam criteria are + +premature. J Clin Endocrinol Metab, 2006; 91: 781-5. + +7. Boomsma CM, Eijkemans MJ, Hughes EG & al, A meta-analysis + +of pregnancy outcomes in women with polycystic ovary + +syndrome. Hum Reprod Update, 2006; 12: 673-83. + +8. Burghen GA, Givens JR & Kitabchi AE, Correlation of + +hyperandrogenism with hyperinsulinism in polycystic ovarian disease. Journal of Clinical Endocrinology and Medicine 1980; + +50: 113-116. + +9. Chang RJ, Nakamura RM, Judd Hl & Kaplan SA, Insulin + +resistance in nonobese patients with polycystic ovary syndrome. + +J Clin Endocrinol & Metabol, 1983; 57: 356-359. + +10. Coviello AD, Legro RS & Dunaif A, Adolescent girls with + +polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance. J Clin Endocrinol + +Metab, 2006; 91: 492-7. + +11. Jialal I, Naiker P, Reddi K & al, Evidence for insulin resistance in + +nonobese patients with polycystic ovarian disease. J Clin + +Endocrinol & Metabol, 1987; 64: 1066-1069. + +12. Ovesen P, Moller J, Ingerslev HJ & al, Normal asal and insulin + +stimulated fuel metabolism in lean women with polycystic ovary + +syndrome. J Clin Endocrinol & Metabol, 1993; 77: 1636-1640. + +13. Holte J, Bergh T, Berne C & al, Enhanced early insulin response + +to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance. J Clin + +Endocrinol & Metabol, 1994; 78: 1052-1058. + +14. McCartney CR, Prendergast KA, Chhabra S & al, The + +association of obesity and hyperandrogenemia during the pubertal transition in girls: obesity as a potential factor in the genesis of postpubertal hyperandrogenism. J Clin Endocrinol + +Metab, 2006; 91: 1714-22. + +15. Robinson S, Kiddy D, Gelding SV & al, The relation of insulin + +sensitivity to menstrual pattern in women with hyperandrogenism and polycystic ovaries. Clin Endocrinol, 1993; 39: 351-355. + +16. Berneis K, Rizzo M, Lazzaroni V & al, Atherogenic lipoprotein + +phenotype and low-density lipoproteins size and subclasses in women with polycystic ovary syndrome. J Clin Endocrinol + +Metab, 2006; 24 [Epub ahead of print]. + +17. Blass KM, Newschaffer CJ, Klag MJ & Bush TL, Plasma + +lipoprotein levels as predictor of cardiovascular death in women. + +18. + +Rajkhowa M, Neary RH, Knmptala P & al, Altered composition of high density lipoproteins in women with polycystic ovary + +syndrome. J Clin Endocrinol & Metabol, 1997; 82: 3389-3394. + +19. + +Lobo RA & Carmina E, Mishell's Textbook of Infertility, Contraception, and Reproductive Endocrinology. 4th ed. + +Boston: Blackwell; 1997: 363-83. + +20. + +Ek I, Arner P, Bergqvist A & al, Impaired adipocyte lipolysis in nonobese women with the polycystic ovary syndrome: a possible link to insulin resistance? J Clin Endocrinol Metab, 1997; 82: + +21. + +1147-53. + +Glueck CJ, Papanna R, Wang P & al, Incidence and treatment of metabolic syndrome in newly referred women with confirmed + +polycystic ovarian syndrome. Metabolism, 2003; 52: 908-15. + +22. + +Zimmermann S, Phillips RA, Dunaif A & al, Polycystic ovary syndrome: lack of hypertension despite profound insulin + +resistance. J Clin Endocrinol Metab, 1992; 75: 508-13. + +23. + +Dahlgren E, Janson PO, Johansson S & al, Polycystic ovary syndrome and risk for myocardial infarction: evaluated from a risk factor model ased on a prospective population study of + +women. Acta Obstet Gynecol Scand, 1992; 71: 599-604. + +24. + +Dahlgren E, Johansson PO, Lindstedt G & al, Women with polycystic ovary syndrome wedge resected in 1956 to 1965: a long-term follow-up focusing on natural history and circulating + +hormones. Fertil Steril, 1992; 57: 505-13. + +25. + +Kelly CJG, Speirs A, Gould GW & al, Altered vascular function in young women with polycystic ovary syndrome. J Clin + +Endocrinol Metab, 2002; 87: 742-6. + +26. + +Paradisi G, Steinberg HO, Hempfling A & al, Polycystic ovary syndrome is associated with endothelial dysfunction. Circulation, 2001; 103: 1410-5. + +27. + +Mather KJ, Verma S, Corenblum B & Anderson TJ, Normal endothelial function despite insulin resistance in healthy women with the polycystic ovary syndrome. J Clin Endocrinol Metab, + +28. + +2000; 85: 1851-6. + +Paradisi G, Steinberg HO, Shepard MK & al, Troglitazone therapy improves endothelial function to near normal levels in women with polycystic ovary syndrome. J Clin Endocrinol + +Metab, 2003; 88: 576-80. + +29. + +Wild RA, Grubb B, Hartz A & al, Clinical signs of androgen excess as risk factors for coronary artery disease. Fertil Steril, + +30. + +1990; 54: 255-9. + +Birdsall MA, Farquhar CM & White HD, Association etween polycystic ovaries and extent of coronary artery disease in women having cardiac catheterisation. Annals of Inter Med, + +31. + +1997; 126: 32-35. + +Dahlgren E, Janson PO, Johansson S & al, Polycystic ovary syndrome and risk for myocardial infarction. Evaluated from a risk factor model ased on a prospective population study of + +women. Acta Obstet Gynecol Scand, 1992; 71: 559-604. + +Handa N, Matsumoto M, Meade H & al, Ultrasonic evaluation + +32. + +of early carotid atherosclerosis. Stroke, 1990; 21: 1567-1572. + +33. + +Guzick DS, Talbott EO, Sutton-Tyrell K & al, Carotid atherosclerosis in women with polycystic ovary syndrome: initial results from case control study. Am J Obstetr & Gynecol, 1996; + +174: 1224-1229. diff --git a/outputs/multi_column/0be9ba925bc2e3164ce649b02e3e29a07239_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/0be9ba925bc2e3164ce649b02e3e29a07239_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5f808c45813824497aec4032dacbab7cee57d02f --- /dev/null +++ b/outputs/multi_column/0be9ba925bc2e3164ce649b02e3e29a07239_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +# Medicinal value of Lepidium latifolium: + +Lepidium latifolium has many medicinal properties. It is widely used as stomach tonics and diuretics (Navarro et al., 1994). Navarro et al. (1994), reported that the aqueous extract of Lepidium latifolium leaves improved the urinary excretion among rats. The leaf extract had given in 100 and 50 mg/kg doses through oral route and intraperitoneal respectively. The standard suggested dose for Lepidium latifolium for man was 3 to 5 gm/day in the form of tea (Navarro et al., 1994). Some reports also suggested that the perennial pepperweed is also used in the treatment of hypertension and it has a property of antihypertensive (Tabassum and Ahmad, 2011). Conde-Rioll et al. (2018), determined that the leaf extract of Lepidium latifolium showed antitumor activity against HT-29, a cultured human colon cancer cell line. + +![](figure) + +![](figure) + +Figure1. Lepidium latifolium + +This cell line was recognized to then CEPT (1cyano-2,3-epithiopropane) compound that present in leaf extract. They also found that Lepidium latifolium juice also exhibits in vivo high antitumor activity against various cell lines (Conde‐Rioll et al. 2018). But Hanschen et al. results did not find the apoptotic effects of CEPT against human cancer cell lines. However, they suggested that the antitumor activity should be attributed to mitochondrial dehydrogenase inhibition activity of HCC (human hepatocellular carcinoma) cells (Hanschen et al., 2015). Lepidium latifolium leaves extracts also comprises many natural antioxidants. These antioxidants act as reducing agents, chelating agents, free radical scavengers and antioxidative defense enzyme systems activator which suppress the ion damages in biological systems (Kaur et al.,2013). Lepidium latifolium ethanolic leaf extract also comprises many natural antioxidants which show free radical sifting activity. These compounds are Kaemferol- 3 -O-robinoside -7- O - (2″″- (E) - feruloyl)- sophoroside, Quercetin – 3 – O – \(\beta\) – D – sophoroside – 7 – O – \(\alpha-\) L-rhamnoside, Kaempferol \(-7-\mathrm{O}-\alpha-\mathrm{L}\) rhamnopyranoside and Apetalumoside B6 (Xiang et al., 2018). Lepidium latifolium also uses traditionally against kidney related diseases and renal lithiasis (Tabassum and Ahmad, 2011). This plant also show activities against prostatic hyperplasia (Lisciani et al., 1984). Mechanism of light adaptation in Lepidium latifolium: Lepidium latifolium plant grows in harsh environment. Temperature is less than -20°C during night which shows its biochemical adaptation. Several studies have been started to connect its low temperature surviving ability with the low temperature regulated genes from the cold desert Ladakh (Aslam et al., 2009). Ahmed et al. (2010), demonstrated that seeds of Lepidium latifolium had not germinated in dark under saline and non-saline conditions. Whereas, Bhat et al. ( 2016), study revealed that L. latifolium has high capability of physiological plasticity which allows it to grow in high altitude area of Ladakh? It comprises light dependent regulation of xanthophyll conversion, responses of antioxidants to environmental stresses and photosynthetic efficiency mechanism for high photosynthetic efficiency. They also found that there is no considerable photoinhibition in Lepidium latifolium in the resource limited conditions which suggest its adaptive potential. Francis and Warwick (2007), observed the germination response of Lepidium latifolium seeds against light, increasing salinity and reducing water potential. They found that seed germination was highest in light (30% after 14 days) environment and light/dark alternating environments. Seed germination was reduced to 4% + +53 Environment Conservation Journal + +![](figure) diff --git a/outputs/multi_column/0be9ba925bc2e3164ce649b02e3e29a07239_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/0be9ba925bc2e3164ce649b02e3e29a07239_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7a65637e473593e71bf411765cb0d803d48166af --- /dev/null +++ b/outputs/multi_column/0be9ba925bc2e3164ce649b02e3e29a07239_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,39 @@ +(for light/dark) and 16% (light), when seeds were exposed to salt stress. Sonnentag et al. (2011), suggested that the appropriate amount of light reached even to the lowest leaves of the Lepidium latifolium plant. + +![](figure) + +![](figure) + +Figure2. Medicinal uses of Lepidium latifolium. + +latifolium has several medicinal uses against many diseases and it is tolerant to extreme temperature and light conditions due to which it can grow in Ladakh area. + +# References + +Ahmed, M. Zaheer and M. Ajmal Khan. 2010. “Tolerance and Recovery Responses of Playa Halophytes to Light, Salinity and Temperature Stresses during Seed Germination.” Flora - Morphology, Distribution, Functional Ecology of Plants 205(11): 764–71. + +Aslam, Mohammad et al. 2009. “Isolation of Cold Stress-Responsive Genes from Lepidium Latifolium by Suppressive Subtraction Hybridization.” Acta Physiologiae Plantarum 32(1): 205. + +Ballabh, Basant, and Chaurasia. O.P. 2007. “Traditional Medicinal Plants of Cold Desert Ladakh—Used in Treatment of Cold, Cough and Fever.” Journal of Ethnopharmacology 112(2): 341–49. + +# Conclusion + +Several medicinal plants have grown in Ladakh area. Ladakh is mountainous region located in the Trans-Himalayan area. Lepidium latifolium (also known as Perennial pepperweed) is an invasive plant, mainly found in southern east Europe and western Asia. It belongs to the family Brassicaceae and Lepidium genera have more than 150 species. It is also found in the mountainous region of Ladakh area in India. Traditional herbalists used Lepidium latifolium in the treatment of many diseases. It is widely used as vegetable and in salads in cold desert Ladakh. It has numerous medicinal properties and used in the treatment of many diseases. Lepidium latifolium is mainly used as stomach tonics and diuretic. It is also used in kidney related diseases. At some places, it is also used in the treatment of hypertension and prostatic hyperplasia. Many studies reported the diuretic activity of Lepidium latifolium. Navarro et al. study also revealed the standard dose for human of Lepidium latifolium leaves was 3 to 5 gm/day in the form of tea for improved urinary excretion. Lepidium latifolium leaves extract and juices also exhibit the anti-tumor activities. It grows in very low temperature of Ladakh. Many studies revealed that the Lepidium latifolium has high capability of physiological plasticity due to which it grows in the high altitude and low temperature region of Ladakh. It can be concluded that Lepidium + +Ballabh, Basant, O. P. Chaurasia, Zakwan Ahmed, and Shashi Bala Singh. 2008. “Traditional Medicinal Plants of Cold Desert Ladakh—Used against Kidney and Urinary Disorders.” Journal of Ethnopharmacology 118(2): 331– 39. + +Bhat, Hilal A., Tarandeep Kaur, Rohini Bhat and Dhiraj Vyas. 2016. “Physiological and Biochemical Plasticity of Lepidium Latifolium as ‘Sleeper Weed’ in Western Himalayas.” Physiologia Plantarum 156(3): 278–93. + +Conde‐Rioll, María et al. 2018. “Antitumor Activity of Lepidium Latifolium and Identification of the Epithionitrile 1-Cyano-2,3-Epithiopropane as Its Major Active Component.” Molecular Carcinogenesis 57(3): 347–60. + +Francis, Ardath and Suzanne I. Warwick, 2007. “The Biology of Invasive Alien Plants in Canada. 8. Lepidium Latifolium L.” Canadian Journal of Plant Science 87(3): 639–58. + +Grover, Atul et al. 2012. “Random Genomic Scans at Microsatellite Loci for Genetic Diversity Estimation in Cold-Adapted Lepidium Latifolium.” Plant Genetic Resources 10(3): 224–31. Gupta, Sanjay Mohan, Atul Grover and Zakwan Ahmed, 2012. “Identification of Abiotic Stress Responsive Genes from Indian High Altitude Lepidium Latifolium L. (Short Communication).” Defence Science Journal 62(5): 315– 18. + +Hanschen, Franziska S. et al. 2015. “The Brassica Epithionitrile 1-Cyano-2,3-Epithiopropane Triggers Cell Death in Human Liver Cancer Cells in Vitro.” Molecular Nutrition & Food Research 59(11): 2178–89. + +Jouad, H. et al. 2001. “Ethnobotanical Survey of Medicinal Plants Used for the Treatment of Diabetes, Cardiac and + +## 54 Environment Conservation Journal + +![](figure) diff --git a/outputs/multi_column/0c6c8f76cdecc74698360d34af4d58e721a0_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0c6c8f76cdecc74698360d34af4d58e721a0_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b89d148f38955c57a78bee22a9bfca3c454eba29 --- /dev/null +++ b/outputs/multi_column/0c6c8f76cdecc74698360d34af4d58e721a0_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +# On output sampling based sliding mode control for discrete time systems + +Srinath Govindaswamy, Thierry Floquet, and Sarah K. Spurgeon + +Abstract— This paper considers the problem of designing an output feedback sliding mode controller for discrete time systems. A minimal set of current and past outputs are identified to determine an extended output signal. This augmented system permits the design of a sliding manifold based upon output information only, which renders the sliding mode dynamics stable. It is shown that any transmission zeros of the augmented system will also be among the transmission zeros of the original plant. The class of discrete time systems which can be stabilised by output feedback sliding mode control is broadened by the proposed method. The theoretical results are constructive and are demonstrated via a motivational example which could not previously be solved by static output feedback. + +## I. INTRODUCTION + +In continuous time, a sliding mode is generated by means of discontinuities in the control signals about a surface in the state space [27]. It is required that the discontinuity surface, usually called the sliding surface, is attained from any initial condition in a finite time interval. For an appropriately selected controller, the motion on the surface, or sliding mode is completely insensitive to any matched uncertainty in the system [27], [6]. In a discrete control implementation, the control signal is held constant during the sample period and hence it is not possible, in general, to attain a sliding mode which requires the control to switch at infinite frequency. As a result, the invariance properties of continuous time sliding-mode control can be lost. The obvious solution of sampling at high frequency, which will closely approximate continuous time, may not be possible for given hardware specifications. This has led to interest in the idea of discrete time sliding-mode control (DSMC). For the case of uncertain discrete systems, it is not possible to ensure the states remain on a surface within the state space and for this reason much of the early DSMC literature focused on establishing a discrete time counterpart to the (continuous time) reachability condition [21], [11], [3]. A comprehensive overview of these early developments is given in [18]. One distinctive feature is that DSMC does not necessarily require the use of a discontinuous control strategy [24]. The results presented in [24], [13] show that an appropriate choice of sliding surface, used with the equivalent control required to ensure sliding, can guarantee a bounded motion about the + +Srinath Govindaswamy and Sarah Spurgeon are with the Instrumentation, Control & Embedded Systems Research Group, Department of Electronics, University of Kent, Canterbury CT2 7NT, UK. S.K.Spurgeon@kent.ac.uk + +T. Floquet is with LAGIS UMR CNRS 8146, École Centrale de Lille, BP 48, Cité Scientifique, 59651 Villeneuve d’Ascq and with Équipe Projet ALIEN, INRIA Lille-Nord Europe, France. thierry.floquet@ec-lille.fr + +surface in the presence of bounded matched uncertainty and that the use of a relay/switch in the control law is detrimental to performance. Early contributions in sliding mode control were developed in a framework in which all the system states are available. This may not be realistic for practical engineering problems and has motivated the need for output feedback controllers. A number of algorithms have been developed for robust stabilization of uncertain systems which are based on sliding surfaces and output feedback control schemes [28], [5]. In [28], a geometric condition is developed to guarantee the existence of the sliding surface and the stability of the reduced order sliding motion. Edwards and Spurgeon derived an algorithm [5], [6] which is convenient for practical use. Based on the work in [28], some dynamic feedback sliding mode controllers have been proposed [15], [22]. In all the above output feedback sliding mode control schemes, it is an a priori requirement that the system under consideration is minimum phase and relative degree one and that a particular sub-system must be output feedback stabilisable [6]. Compared with continuous time sliding-mode strategies, the design problem in discrete time is much less mature. Other than early work in [23], much of the literature assumes all states are available [13], [10], [26]. Discrete sliding mode control schemes which have restricted themselves to output measurements alone have often been observer based schemes with or without disturbance estimation [17], [25]. Recent exceptions have been the work in [12] which considers both static and dynamic output feedback problems, and the discrete time versions of certain higher-order sliding-mode control schemes [1], [2]. For continuous time systems, it was shown in [9] that the relative degree condition associated with the solution of the existence problem can be weakened if a classical sliding mode observer is combined with sliding mode exact differentiators to generate additional independent output signals from the available measurements. In this paper, it will be shown that by using the output signal at the current time instant together with a limited amount of information from previous sample instants, the class of systems for which an output feedback based sliding mode controller can be developed is significantly broadened. The paper is structured as follows. Section 2 presents the problem motivation. The existence problem is considered in Section 3 and a solution to the reachability problem is given in Section 4. A motivational example, from the class of discrete systems which could not previously be stabilised by output feedback sliding mode control, is presented to diff --git a/outputs/multi_column/0cf93d937e0f519965d4ff67daec8dd5dea1_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/0cf93d937e0f519965d4ff67daec8dd5dea1_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..dcdfadb5d65a208623a1fb81168fd986f0100cea --- /dev/null +++ b/outputs/multi_column/0cf93d937e0f519965d4ff67daec8dd5dea1_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,13 @@ +> This page was read from its image by a model (olmocr); the PDF's own text layer is an OCR layer, not the author's text.[^inferred] + +as in rats, this structure has a high content of DA but contains very little norepinephrine (3). TH-immunopositive boutons in rat striatum, like those in the primate cortex, are invariably of the symmetric type and their most common targets are dendritic spines, although other axosomatic and axoshaft synapses are also present (26, 27). Moreover, the dendritic spines of the striatonigral projection neurons that receive input from TH-reactive boutons also receive input from an unstained asymmetric synaptic specialization. Freund et al. (26) suggested that an important function of DA in the caudate nucleus is to block the spread of excitatory signals at the level of the individual spine. The startling similarity in the targets and mode of termination of DA afferents in the cerebral cortex and caudate nucleus suggest a common principle of synaptic and functional organization in these two anatomically and functionally closely related structures. The similarity is the more impressive as TH boutons do not invariably form symmetric synapses in all brain regions. For example, in rat hippocampus, TH-positive boutons establish exclusively asymmetric synapses on the dendritic spines of hippocampal pyramidal neurons, whereas their contacts on GABAergic nonpyramidal neurons are symmetric (28). + +DA Synaptic Complex: Mechanism of Cortical Modulation. The most commonly reported direct effect of DA on the spontaneous activity of prefrontal neurons is inhibition, and this effect can be produced by local microiontophoretic application of DA (29), by systemic administration of DA agonists (30), or by stimulated release consequent to electrical stimulation of the ventral tegmental area (VTA), where the cells of origin of the cortical DA projection lie (31, 32). Indeed, DA release produced by stimulation of brainstem VTA or iontophoretic application of DA can be shown to attenuate the excitatory response of rodent prefrontal neurons to thalamic stimulation (31) or to tail pinch (32). Similarly, DA applied to the prefrontal cortex of monkeys increases the signal-to-noise ratio in single neuronal activity recorded during a behavioral task when the animal was preparing to respond, whereas DA antagonists had the opposite effect (33). It is not known where or how these effects are mediated—i.e., via a direct effect on pyramidal neurons or via interneurons, or both. The present evidence that spines are the targets of symmetric DA-positive boutons and, furthermore, that an asymmetric bouton is also involved may provide some clues. Given that the spines of pyramidal cells in a variety of cortical areas receive a variety of excitatory synapses and can be the site of large EPSPs (34), it would appear that the DA terminal endings on spines are strategically placed within the cortical circuitry to alter local spine responses to excitatory inputs and, through these, make a contribution to the overall excitability of projection neurons in the cortex. + +We thank G. Aghajanian, G. Shepherd, D. Meinecke, and P. Rakic for their helpful comments. This work was supported by Grant MH38546 and by a Javits Center of Excellence in Neuroscience Grant (NS22807). + +1. Creese, I., Burt, D. P. & Snyder, S.H. (1976) Science 192 , 481–483. + +2. Thierry, A.-M., Stinus, L. & Glowinski, J. (1973) Science 182 , 499–501. 3. Brown, R. M., Crane, A. M. & Goldman, P. S. (1978) Brain Res. 124 , 133–150. 4. Simon, H., Stinus, L. & LeMoal, M. (1980) Nature (London) 286 , 150–151. 5. Brozoski, T. J., Brown, R. M., Rosvold, H. E. & Goldman, P. S. (1979) Science 205 , 929–931. 6. Lewis, D. A., Foote, S. L., Goldstein, M. & Morrison, J. H. (1988) Brain Res. 449 , 225–243. 7. Berger, B., Trottier, S., Verney, C., Gaspar, P. & Alvarez, C. (1988) J. Comp. Neurol. 273 , 99–119. 8. Gaspar, P., Berger, B., Febvret, A., Vigny, A. & Henry, J.-P. (1989) J. Comp. Neurol. 279 , 249–271. 9. Chagnaud, J. L., Mons, N., Tuffet, S., Grandier-Vazeilles, S. & Geffard, M. (1987) J. Neurochem. 49 , 487–494. 10. Pickel, V., Joh, T. & Reis, D. (1975) Brain Res. 85 , 295–300. 11. Van Eden, C. G., Hoornemann, E. M. D., Buijs, R. M., Matthussen, M. A. H., Geffard, M. & Uylings, H. B. J. (1987) Neuroscience 22 , 849–862. 12. Somogyi, P. & Takagi, H. (1982) Neuroscience 7 , 1779–1783. 13. Hsu, S. M., Raine, L. & Fanger, H. (1981) J. Histochem. Cytochem. 29 , 577–580. 14. Seguela, P., Watkins, K. C. & Descarries, L. (1988) Brain Res. 442 , 11–22. 15. Frotscher, M. & Leranth, C. (1988) Histochemistry 88 , 313–319. 16. Jones, E. G. & Powell, T. P. S. (1970) Philos. Trans. R. Soc. Lond. B. 257 , 45–62. 17. Peters, A. & Feldman, M. L. (1976) J. Neurocytol. 5 , 63–84. 18. Lund, J. S. & Lund, R. D. (1970) Brain Res. 17 , 25–45. 19. Hokfelt, T., Johansson, O., Fuxe, K., Goldstein, M. & Park, D. (1977) Med. Biol. 55 , 21–40. 20. Colonnier, M. (1981) in The Organization of Cerebral Cortex , ed. Schmitt, F. O. (MIT Press, Cambridge, MA), pp. 125–153. 21. Papadopoulos, G. C., Parnavelas, J. G. & Buijs, R. (1987) Neurosci. Lett. 76 , 275–279. 22. Molliver, M. E. & Kristt, D. A. (1975) Neurosci. Lett. 1 , 305–310. 23. Jones, E. G., DeFelipe, J., Hendry, S. H. C. & Maggio, J. E. (1988) J. Neurosci. 8 , 1206–1224. 24. Hendry, S. H. C., Houser, C. R., Jones, E. G. & Vaughn, J. E. (1983) J. Neurocytol. 12 , 639–660. 25. Marin-Padilla, M. (1984) in Cerebral Cortex , eds. Peters, A. & Jones, E. G. (Plenum, New York), Vol. 1, pp. 447–521. 26. Freund, T. F., Powell, J. F. & Smith, A. D. (1984) Neuroscience 13 , 1189–1215. 27. Pickel, V. M., Beckley, S., Joh, T. H. & Reis, D. J. (1981) Brain Res. 225 , 373–385. 28. Frotscher, M. & Leranth, C. (1987) J. Comp. Neurol. 243 , 58–70. 29. Bunney, B. S. & Agajanian, G. K. (1976) Life Sci. 19 , 1783–1792. 30. Peterson, S. L., St. Mary, J. S. & Harding, N. R. (1987) Brain Res. Bull. 18 , 723–729. 31. Ferron, A., Thierry, A.-M., Le Douarin, C. & Glowinski, J. (1984) Brain Res. 302 , 257–265. 32. Thierry, A.-M., Mantz, J., Milla, C. and Glowinski, J. (1988) in Proceedings from the Conference on the Mesocorticolimbic Dopamine System , eds. Kalivas, P. W. and Nemeroff, C. B. (New York Acad. Sci., New York), pp. 101–111. 33. Sawaguchi, T. & Matsumura, M. (1985) Neurosci. Res. 2 , 255–273. 34. Shepherd, G. (1974) The Synaptic Organization of the Brain (Oxford Univ. Press, Oxford, U.K.), pp. 321–328. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0d7383fad5205f1faaacd0713f4f08509af5_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/0d7383fad5205f1faaacd0713f4f08509af5_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..89f82ea18d01a2835eaa32ecf410900d99f5090a --- /dev/null +++ b/outputs/multi_column/0d7383fad5205f1faaacd0713f4f08509af5_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,59 @@ +![](figure) + +![](figure) + +# Key Benefits + +## Broadcaster + +Additional revenue streams for the sports + +- Multi-platform Publishing value chain, by directly facilitating commercial activities over the medium. + +- New novel way of interactive in-content advertising offering an added value easy to use e-commerce system (embedded advertising) thus increasing the effectiveness of advertising by narrowing the gap between advertisement and consumption. + +- Increase the subscription base by offering new added value enhanced services to the subscribers with the provision of an innovative low-cost technology. + +- Offers the thrill of instant betting via interactive TV and 3G mobile phone. + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +# Scenario 1 + +John is watching a football match of his favourite team. A foul has been committed and overlay graphics display the distance from the goal line. A graphic overlay notifies him that a new bet placement option has become available. Interactive elements on the respective graphics overlays give him the opportunity place a Bet concerning the outcome of the free kick. He clicks on the statistics label that follows the player to access the available statistics information. He decides to place the bet through the STB remote control. He follows the on-screen instructions and proceeds to place a bet. Upon bet placement and confirmation he receives a notification message that verifies the transaction. A replay of the Free kick is broadcasted, this time new graphics elements appear on the screen, the player’s shirt is highlighted. John selects the player’s shirt and an advertisement appears on the screen with the option to redirect him to an e-commerce website for further information and ordering. + +- Offers a virtual presence in a football game or a horse-racing event that could lead to an increase of on-line betting. + +## Subscriber + +- Profile based filtering offering the viewer control over the received information. + +- Advanced On-line Betting environment for an enhanced betting experience. + +- The Interactivity and the Visualisation of complementary information offers an enhanced sports viewing experience. + +- Ergonomically designed interfaces for turning consumer devices into powerful platforms for interactive entertainment. + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +# Scenario 2 + +Mark is traveling by train and he decides to view a live F1 race on his 3G wireless computer. He logs in the Melisa service and chooses to watch the televised race watching the normal video feed of the broadcaster. He clicks on the classification button and the Drivers Classification Panel displays the current drivers positions. Mark chooses the graphical representation mode. In this mode the exact position of all cars, is shown as a graphical representation on a Virtual Track in real time. Visual cues, such as color and car number, show the relative position of the drivers in the track. Mark clicks on his favourite driver’s car to display the available statistical information. He sees the drivers sponsor and he decides to click on the Sponsor’s logo to receive further information. This action redirects him the to sponsors e-commerce Web Site for on-line shopping. diff --git a/outputs/multi_column/0d767c7cab3af7117e33d74252a524497957_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0d767c7cab3af7117e33d74252a524497957_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ffd78c08b7cd8edc9491b2b2c332e97dc9d32d6e --- /dev/null +++ b/outputs/multi_column/0d767c7cab3af7117e33d74252a524497957_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +then the pressure difference between the basement and the attic is likely to increase air infiltration into the basement. It is usually a good idea to seal this flow path. + +# Leaking Ducts Can Also Be Hazardous to Your Health + +These are all signs that serious duct leakage may be which over time has accumulated on the surface as the air is being pulled through the insulation. + +# Comfort and Sizing + +Air conditioning cooling capacity is often measured in "tons". A ton of cooling represents the heat energy required to melt one ton of ice in 24 hours. Because duct systems lose energy that is supposed to heat or cool the house, they change the effective capacity of the heating and cooling equipment. For example, a three ton air conditioner connected to a duct system of 70% efficiency effectively becomes a two ton air conditioner. A duct system guaranteed to reduce duct leakage would allow the homeowner to purchase a smaller air conditioning system. + +Simulation results showed that improved ducts (low leakage) and improved system installation (minimally leaking and insulated ductwork) can allow the use of a smaller nameplate capacity air conditioner without reducing the actual heating or cooling delivered at the air supply registers to the occupied space or the pulldown time. (A three ton unit can be used rather than a four ton for a typical house). If system nameplate capacity is unchanged, improving duct systems results in the pulldown being reduced by more than an hour, so the occupants become comfortable sooner. + +Unfortunately, the old axiom of “out-of-sight, out-of-mind” applies to most aspects of an air conditioning system. For most homeowners, as long as the system is keeping them cool, they usually do not give it much thought. What they do not see is how much their system is costing them per year. Most duct systems are installed in attics or building cavities where they are rarely seen or inspected. The lower quality of air duct currently on the market may lead to poor seals, loose fittings and duct runs, and tears in the system that mean additional leakage, which has already been addressed at length. Not only does this mean the homeowner has an inefficient system, but a leaking ductwork is unhealthy for the occupants as well. + +# THE GUSTAFSON SOLUTION + +Gustafson is the world leader in HVAC air duct systems, but until now has never offered an option for the residential market. The company’s G3 and HV2 self-sealing gasketed fittings provide the tightest fitting ducts available, that are easy to install and do not require the sealant that is normally required for most duct systems. Gustafson’s HV2 solution offers a true win/win situation for all parties involved. The homeowner will reduce their average cooling cost by greater than 50%. Since the HV2 gasket reduces mold and dust distribution, the homeowner’s family will have safer air distributed throughout the house. Furthermore, the HV2 gasket insures that fiberglass insulation will not be sucked into the system and distributed throughout the house. Round metal ductwork is also easier to clean than conventional ductwork, which further reduces dust distribution throughout the house. All of this may reduce illness as well as costly doctor’s visits. The Gustafson ductwork also means the homeowner can purchase a smaller air conditioning system which will use less energy. The system will run more efficiently, which means it will last longer and avoid costly repairs. On a larger level, energy consumption is reduced, along with toxic diff --git a/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_6_pg1_pg1_repeat1.md b/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_6_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..5034591b57f0fbc49ee3c22ca882233edce911ef --- /dev/null +++ b/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_6_pg1_pg1_repeat1.md @@ -0,0 +1,140 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +FIRST FLOOR + +Finishes Ceiling + +o Mineral Fiber Panels natural finish. + +Finishes Doors and Windows + +o Heavy-duty noise blocking barrier laminated to 1 in. thick sound absorbing foam. + +The noise blocking door cover, sound stopping perimeter seal and door sweep. + +o Door frame Sound Barrier tape & acoustical sealant to fill in gaps, holes and cracks in the door and frame + +o Clear Varnish on doors exposing the timber. + +o Aluminium Windows-factory finish with a timber coating. + +7.2.10 Braal Area/Social Area + +Finishes Walls + +o Traditional Scratch and Paint. + +o Flush Jointed Face Brick. + +Finishes Floors + +o Olive Sand Mazista Floor Tile. + +Finishes Doors + +o Clear Varnish on doors exposing the timber. + +7.2.11 Exhibition Area + +Finishes Columns and Beams + +o In-Situ Concrete. + +o Indiscriminate Scratch and paint with different colours (representing a rainbow nation). + +Finishes Walls + +o Traditional Scratch and Paint. + +o Flush Jointed Face Brick. + +o Stock Brick plastered inside and Stone Cladding outside. + +o Crafted Steel representing music elements on walls openings. + +Finishes Floors + +o Suntan Weave Floor Tile +Manufactured by Union Flooring Tile. + +Finishes Soffit + +o In-Situ Concrete. + +o Traditional Scratch and Paint. + +Finishes Ceiling + +o Mineral Fiber Panels natural finish. + +o Rough-cast and paint. + +Finishes Doors and Windows + +o Clear Varnish on doors exposing the Timber. + +o Aluminium doors-factory finish with a timber coating. + +o Aluminium Windows-factory finish with a timber coating. + +7.2.12 Board Room + +Finishes Columns and Beams + +o In-Situ Concrete. + +o Indiscriminate Scratch and Paint. + +Finishes Walls + +o Traditional Scratch. + +o Carpet Manufactured by Belgotex Carpet. + +Finishes Floors + +o Carpet Manufactured by Belgotex Carpet. + +o Impact Barrier Plus underlayment (Sound absorption material). + +Finishes Soffit + +o Traditional Scratch. + +o Carpet Manufactured by Belgotex Carpet. + +Finishes Ceiling + +o Mineral Fiber Panels natural finish. + +Finishes Doors and Windows + +o Clear Varnish on doors exposing the timber. + +o Aluminium Windows-factory finish with a timber coating. + +7.2.13 Lecture Theatre + +Finishes Walls + +o Traditional Scratch and Paint. + +o Carpet Manufactured by Belgotex Carpet. + +o Impact Barrier Plus underlayment (Sound absorption material). + +Finishes Floors + +o Timber Floor Slates by Specialist. + +Finishes Ceiling + +o Mineral Fiber Panels +natural finish. + +Finishes Doors + +o Clear Varnish on doors +exposing the timber. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a8d7d3af23ab7a6923144c4e0760718a49a732bf --- /dev/null +++ b/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,102 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +7.4 Properties of Materials + +7.4.1 Quiet Barrier + +A flexible, 2lb per sq./ft: 1/4 in. thick, high density material with a smooth surface designed to reduce noise transmission between two spaces. Applications include reducing airborne noise transmission through walls, ceilings and floors. + +□ High performance soundproofing material for reducing airborne noise. + +□ May be used behind drywall in wall and ceiling assemblies or sandwiched between existing and new drywall. + +□ Use in flooring systems to increase sound transmission class. + +□ Only 1/4 in. thick yet weighs 2lb./sq. ft. for maximum noise blocking. + +□ Used for both residential and commercial soundproofing applications. + +(http://soundprooffoam.com/) + +7.4.2 Impact Barrier-plus-temp + +Premium grade carpet underlayment designed to reduce the transfer of sound from impact. + +□ Extremely effective in reducing impact sound. + +□ Very effective in reducing airborne sound transmission. + +□ Extra padding for additional acoustic performance and comfort. + +□ Extends the life of your carpet. + +□ Reusable under normal conditions & traditional installation methods. + +□ Engineered for plush carpets. + +□ Made with approximately 60% recycled materials. + +□ 1/2 in. thick easy to cut and install. +(ibid) + +7.4.3 Pyramid-Family + +High performance, sound absorbing foam panel designed to reduce echo within an environment. Enhances sound quality and aesthetics of a recording or listening environment. + +□ Excellent echo reduction. + +□ 3D pyramid pattern adds architectural interest. + +□ Variety of colors, see color options. + +□ Light weight, open cell polyurethane foam. + +□ Easy to cut and install, see installation method. + +□ UL94 HF-1 flammability rating. +(ibid) + +7.4.4 Quiet Batt Fibercraft + +A premium high-performance acoustical / thermal insulation manufactured from 80% recycled cotton fibers. Quiet batt offers superior noise reduction versus typical fiberglass, cellulose and foam insulations. + +□ No itch, easy to handle friction-fit: easy to install. + +□ Superior sound absorbing performance. + +□ 80% + recycled cotton fiber content. + +□ Available in 3-1/2 in. & 5-1/2 in. thickness. + +□ No harmful chemicals or worker discomfort. + +□ Meets "Green" building requirements. +(http://soundprooffoam.com/) + +7.4.5 Carpet + +□ Highly durable construction. + +□ Attractive finished appearance. + +□ perfect for increasing speech privacy. + +□ Outstanding sound absorption performance. +(Ibid) + +7.4.6 Tufcore Ceiling Tiles + +High-performance composite ceiling panel. Especially well-suited to minimize sound transmission between adjacent spaces sharing a common plenum or attic space. + +□ Dual function performance absorbs and blocks sound transmission. + +□ Available in a variety of finish options and edge details + +□ Minimize sound transmission between adjacent spaces sharing a common plenum or attic space. + +□ Gypsum improves sound blocking. + +□ Fiberglass cores improves sound absorbing. +(Ibid) + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_9_pg1_pg1_repeat1.md b/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_9_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4797d691b507c164345acfd8cc973fbade99140d --- /dev/null +++ b/outputs/multi_column/0d7f2cbc54e1b8e58b42a867c3f7620bcd29_page_9_pg1_pg1_repeat1.md @@ -0,0 +1,17 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +7.5 Performance Theatre + +To achieve a good listening environment for music in the Theatres, certain precautions have been adhered to for good results. The walls have been designed to be at divergent angles to prevent standing waves and to help reflect sound to the audience. (refer to fig. 171-172) The side walls are finished with strips of sounding board (reflectors) at certain intervals to help reflect sound to the audience where it is desired. Skimmed plaster board ceiling is fixed at a curving profile to prevent parallel surfaces. The back of the wall is made absorbent by applying Carpet as an absorptive material to decrease the possibilities of echo. Carpet in conjunction with the Impact Barrier Plus underlayment have been applied on the floor for absorptive purposes. + +Fig.171 First Floor sketch Plan Theatre Layout + +7.6 Lecture Theatres + +The principles of sound absorption and reflection adhered to in Lecture Theatres applies the same way as the Performance Theatres. Non-parallel reflective walls have been designed with a reflective ceiling secured at a curving profile (refer to fig. 173). Timber Floor Slates by specialist are applied to the floor and the concept of absorption will be catered by the people occupying the seats. + +Fig.172 Sketch Section C-C + +Fig.173 First Floor sketch Plan Theatre layout + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/multi_column/0d9d4b3a193997395043b891eb0e9370a567_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/0d9d4b3a193997395043b891eb0e9370a567_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..29033865a8d75baa58105d30f995e41413545444 --- /dev/null +++ b/outputs/multi_column/0d9d4b3a193997395043b891eb0e9370a567_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,39 @@ +studies is the higher amplitude of female evoked potentials in different latency ranges. Orozco and Ehlers (1998) reported longer latency and higher amplitude in the P450 component to facial expressions. During a recognition memory task Guillem and Mograss (2005) recorded higher amplitudes of ERPs in female subjects. According to Hoffman and Polich (1999) male subjects produce smaller P200, P300 and N200 components during a classical oddball paradigm. Proverbio et al. (2006) published results on infant happy/distressed expression indicating much larger occipital P110 response in women compared to men. Karakaş et al. (2006) used auditory stimulation and found that the differences in gamma band are independent of gender. We have to note that none of these studies considered a simple physiological stimulation; they have been focused rather on facial expression, also reflecting emotional behavior, attention and working memory. According to Fuster (1995) the phyletic memory is constituted by the structure of primary sensory and motor cortex at birth, which is common to all organisms of the same species. Phyletic memory would be the most basic of all memories, the genetic memory that the organism has formed in the course of evolution by interactions with the surrounding world. The genetically defined structures of primary cortex dedicated to analyzing elementary sensory features and to integrating elementary primitives of movement would form the basic template on which the memory of the individual would develop. In the light of Fuster's definition Başar (2004) emphasized that even “simple light” triggers sensory memory (iconic memory) and that all experiments related to sensory-cognitive processing are interrelated or interwoven with the sensory memory. This is a simple physiological consideration, which includes the necessity to use EPs as control signal. Accordingly, we have to filter out effects of simple light causation in analyzing responses to facial expressions, to attentive processes and also to various types of cognitive loads. In consideration of these facts, the most basic question in our discussion is: “Does simple light evoke differentiations in EROs in comparing female and male subjects? If responses to simple light are anchored with some basic physiological mechanisms, we have to use these results in order to be able to discuss perceptual processes such as face recognition or recognition of facial expressions and/or emotions in a more refined manner. The results of this study also indicate that there are very important differences in the delta band and smaller differences in the beta and gamma frequency ranges. The histogram results presented in Fig. 1A merit important attention. Firstly, we have to note that no differentiations are observed at frontal locations or in the theta frequency range. According to Klimesch et al. (2000) and Başar et al. (1999) a large number of cognitive functions occur in the theta frequency range and at frontal locations. Since we used here a simple light as stimulation, and the subjects did not perform any cognitive tasks, the absence of differentiation in the frontal theta is not surprising. Two other aspects should be mentioned also here. In the vast literature on brain oscillations, the role of gamma oscillations has been mentioned as one of the most important functional key oscillations. In the present study, the gamma response depicts only a differentiating role at the right occipital site. According to our results, the right occipital location is the area which is the most active indicating the differentiation between males and female subjects. + +## 5. Conclusion + +Based also on the results of our previous publications related to oscillatory brain dynamics, we come to the following conclusions: (1) The brain response is a construct in a “multidimensional state” incorporating amplitudes of oscillatory responses, topological coordinates, and changes in the time axis following presentation of the percepts, including delays and prolongations, and coherence between locations. Only a new Cartesian System embracing all these parameters can represent the dynamics of functionality in the brain. (2) It is also important to note that in order to analyze and interpret EROs it seems to be extremely important to consider several causal factors (Başar and Güntekin, 2007). Among these, gender differences should be considered as a fundamental causal factor in the search for functional correlates of EROs. + +# Acknowledgements + +The authors are thankful to Dr. Birgit Mathes for helpful comments on the manuscript. + +# References + +Başar, E., 1980. EEG-Brain Dynamics. Relation Between EEG and Brain Evoked Potentials. Elsevier, Amsterdam. + +Başar, E., 1999. Brain Function and Oscillations: II. Integrative Brain Function. Neurophysiology and Cognitive Processes. Springer-Verlag, Heidelberg. + +Başar, E., 2004. Memory and Brain Dynamics: Oscillations Integrating Attention, Perception, Learning and Memory. CRC Press, Florida. + +Başar, E., Gönder, A., Özesmi, C., Ungan, P., 1975. Dynamics of brain rhythmic and evoked potentials. II. Studies in the auditory pathway, reticular formation, and hippocampus during the waking stage. Biol. Cybern. 5, 145–160. + +Başar, E., Başar-Eroglu, C., Karakaş, S., Schurmann, M., 1999. Are cognitive processes manifested in event-related gamma, alpha, theta and delta oscillations in the EEG? Neurosci. Lett. 15 (259(3)), 165–168. + +Başar, E., Güntekin, B., 2007. A breakthrough in neuroscience needs a “Nebulous Cartesian System" Oscillations, quantum dynamics and chaos in the brain and vegetative system. Int. J. Psychophysiol. 64 (1) (April), 108–122. + +Begleiter, H., Porjesz, B., 2006. Genetics of human brain oscillations. Int. J. Psychophysiol. 60 (2) (May), 162–171. + +Freeman, W.J., 1975. Mass Action in the Nervous System. Academic Press, New York. + +Fuster, J.M., 1995. Memory in the Cerebral Cortex. A Bradford Book. The MIT Press, Cambridge. + +Guillem, F., Mograss, M., 2005. Gender differences in memory processing: evidence from event-related potentials to faces. Brain Cogn. 57, 84–92. + +Güntekin, B., Başar, E., 2007. Emotional face expressions are differentiated with brain oscillations. Int. J. Psychophysiol. 64 (1) (Apr), 91–100. + +Hoffman, L.D., Polich, J., 1999. P300, handedness, and corpus callosal size: gender, modality, and task. Int. J. Psychophysiol. 31, 163–174. + +Jasper, H.H., 1958. The ten-twenty electrode system of the International Federation. Electroencephalogr Clin. Neurophysiol. 10, 371–375. + +Karakaş, S., Tüfekçi, I., Bekçi, B., Çakmak, E.D., Doğutepe, E., Erzengin, O.U., Özkan, A., Arıkan, O., 2006. Early time-locked gamma response and gender specificity. Int. J. Psychophysiol. 60, 225–239. diff --git a/outputs/multi_column/0da8fcaacd0a502c317f9d222a55ffbb81e1_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/0da8fcaacd0a502c317f9d222a55ffbb81e1_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1b78be3e626b8d9e4deb4eef4d032125305265d5 --- /dev/null +++ b/outputs/multi_column/0da8fcaacd0a502c317f9d222a55ffbb81e1_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,39 @@ +floc formation on filterability. Journal of Environmental Science 57, 338–345. + +Leentvaar, J. & Rebhun, M. Effect of magnesium and calcium precipitation on coagulation–flocculation with lime. Water Research 16 (5), 655–662. + +Li, T., Zhu, Z. & Wang, D. S. Characterization of floc size, strength and structure under various coagulation mechanisms. Powder Technology 168 (2), 104–110. + +Li, H., Liu, S., Zhao, J. & Feng, N. Removal of reactive dyes from wastewater assisted with kaolin clay by magnesium hydroxide coagulation process. Colloids and Surfaces A Physicochemical and Engineering Aspects 494, 222–227. + +Li, R., Gao, B., Sun, J. & Yue, Q. Coagulation behavior of kaolinanionic surfactant simulative wastewater by polyaluminum chloride-polymer dual coagulants. Environmental Science and Pollution Research 25, 7382–7390. + +Liu, M., Lu, J., Wei, L., Wang, K. & Zhao, J. Magnesium hydroxide coagulation performance and floc properties in treating high pH reactive orange wastewater. Water Science and Technology 71 (9), 1310–1316. + +Ren, P., Nan, J., Zhang, X. & Zheng, K. Analysis of floc morphology in a continuous-flow flocculation and sedimentation reactor. Journal of Environmental Science 57, 338–345. + +Riera-Torres, M., Gutierrez-Bouzan, C. & Crespi, M. Combination of coagulation–flocculation and nanofiltration techniques for dye removal and water reuse in textile effluents. Desalination 252 (1–3), 53–59. + +Semerjian, L. & Ayoub, G. M. High-pH–magnesium coagulation–flocculation in wastewater treatment. Advances in Environmental Research 7 (2), 389–403. + +Sharp, E. L., Jarvis, P., Parsons, S. A. & Jefferson, B. The impact of zeta potential on the physical properties of ferric- + +NOM flocs. Environment Science and Technology 40 (12), 3934–3940. + +Tan, B. H., Teng, T. T. & Mohd Omar, A. K. Removal of dyes and industrial dye wastes by magnesium chloride. Water Research 34 (2), 597–601. + +Verma, A. K., Dash, R. R. & Bhunia, P. A review on chemical coagulation/flocculation technologies for removal of colour from textile wastewaters. Journal of Environmental Management 93 (1), 154–168. + +Wei, L., Zhao, J., Xu, C. & Liu, M. Experimental analysis of magnesium hydroxide-reactive orange floc formation time and rate in coagulation process. Journal of the Taiwan Institute of Chemical Engineers 45 (5), 2605–2609. + +Wu, X. F., Hu, G. S., Wang, B. B. & Yang, Y. F. Synthesis and characterization of superfine magnesium hydroxide with monodispersity. Journal of Crystal Growth 310 (2), 457–461. + +Yang, Z., Li, H., Yan, H., Wu, H., Yang, H., Wu, Q., Li, H., Li, A. & Cheng, R. Evaluation of a novel chitosan-based flocculant with high flocculation performance, low toxicity and good floc properties. Journal of Hazardous Materials 276, 480–488. + +Zhao, J., Li, W., Jiao, X., Lai, Y. & Guo, X. Floc growth kinetics in magnesium hydroxide coagulation process. Desalination and Water Treatment 52 (22–24), 4334–4341. + +Zhao, J., Shi, H., Liu, M., Lu, J. & Li, W. Coagulation-adsorption of reactive orange from aqueous solution by freshly formed magnesium hydroxide: mixing time and mechanistic study. Water Science and Technology 71 (9), 1310–1316. + +Zhou, Q., Chen, F., Wu, W., Bu, R., Li, W. & Yang, F. Reactive orange 5 removal from aqueous solution using hydroxyl ammonium ionic liquids/layered double hydroxides intercalation composites. Chemical Engineering Journal 285, 198–206. + +First received 18 February 2018; accepted in revised form 9 July 2018. Available online 24 July 2018 diff --git a/outputs/multi_column/0dd31f954c25db440baccc3245daf51b4b55_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0dd31f954c25db440baccc3245daf51b4b55_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f703dc3cb91460dd1e32274f160c7892096cff7f --- /dev/null +++ b/outputs/multi_column/0dd31f954c25db440baccc3245daf51b4b55_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,39 @@ +![](figure) + +#### Panteion University of Social & Political Sciences Department of Social Anthropology + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +# Shamanism and Eco-cosmology - A cross-cultural perspective + +Organised & Conceptualised by Stefano Beggiora, Ca’Foscari University, Venice Diana Riboli, Panteio University, Athens Lidia Guzy, Marginalised & Endangered Worldviews Study Centre, University College Cork, Cork Davide Torri, Heidelberg University, Heidelberg + +### Date: 27 & 28th April 2017 + +## Location: Panteion University of Social and Political Sciences, Conference Room, DESKOI Building, Lagoumitzi and Trikoupi Str., Athens + +This workshop focusses eco-cosmology as a worldview prevalent in shamanic cultures worldwide. Contemporary shamanisms are embedded in analogous ecological knowledge systems relating always to indigenous cosmologies and ontologies (Kopenawa/Albert 2013). Local shamanisms are commonly understood as value systems based on the one hand on cultures of orality, on the other hand on the non-dualistic perspective on human and non-human agencies in a mutually shared world and cosmos (Descola 1992, (2005) 2013, Viveiro de Castro 1998). + +Within the process of industrial extraction of natural resources diverse indigenous / analogous communities are deprived of their fundamental human rights for secured livelihood and preserved ecosystems. An industrial neo-colonial intrusion into mineral rich territories of indigenous and analogous peoples takes place worldwide. With the ecological degradation, vulnerable worldviews of indigenous/ analogous communities and their rituals are critically threatened. These worldviews and local knowledge systems however could be a key for finding local and global solutions for a sustainable and philanthropic global world of cultural and eco-biological diversity and mutuality. + +The 2-days workshop discusses from anthropological, environmental and study of religions perspective local eco-cosmological shamanic knowledge systems and worldviews. It aims on the one hand at displaying the threatened local ecological knowledge transmitted by shamans; on the other hand the workshop aims at a valuation and recognition of shamanic eco-cosmological solutions for a sustainable world and cosmos. + +## Cited works: + +Descola, Philippe 1992. Societies of nature and the nature of society. In Conceptualizing society (ed.) A. Kuper. London: Routledge Descola, Philippe 2013 Beyond Nature and Culture. The University of Chicago Press. Original: Descola, Philippe 2005. Par-delà de la nature et culture. Paris: Gallimard. Kopenawa, Davi / Bruce Albert 2013.The Falling Sky. Words of a Yanomami Shaman. Harvard University Press. Viveiros de Castro, Eduardo 1998. Cosmological Deixis and Amerindian Perspectivism. The Journal of the Royal Anthropological Institute, Vol. 4, No. 3 (Sep., 1998), pp. 469-488 diff --git a/outputs/multi_column/0dd31f954c25db440baccc3245daf51b4b55_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0dd31f954c25db440baccc3245daf51b4b55_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d4919281f2f86ad06f8bd31d2f572cca0930bf4b --- /dev/null +++ b/outputs/multi_column/0dd31f954c25db440baccc3245daf51b4b55_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,67 @@ +![](figure) + +### Panteion University of Social & Political Sciences Department of Social Anthropology + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +![](figure) + +# Programme 27th April + +9.30 – 10.00: Greetings and introduction to the workshop (Athina Athanasiou, Chair of Department of Social Anthropology, Eleana Yalouri, Director of the Laboratory for Anthropological Research For the Organizers: Diana Riboli, ISARS President, Lidia Guzy, University of Cork) + +10.00 – 10.40: Stefano Beggiora + +### Session I + +Chair: Lidia Guzy + +### The Khonds and the Jungle: A Case Study on Indigenous India + +10.40 – 11.20: Davide Torri + +### Sacred and Alive: Human, Non-human and Landscape in the (Buddhist) Himalayas + +11.20 – 11.40 Coffee Break + +11.40 – 12.20 Ivan Tacey + +### Rearranging Cosmic Relations: Cosmopolitics in the Anthropocene + +12.20 -13.20 Discussion + +13.30 – 14. 30 Lunch Break + +14.30 – 15.10 Taj Khan Kalash + +### Session II + +Chair: Naran Bilik + +Ecological Living in Peril: The Case of Kalasha Society in Hindu Kush 15.10 – 15.50 Lu Fangfang The Making of Shaman among the Three Northern Minorities in China and the Hero’s Theme 15.50 – 16.30 Ranju Hasini Sahoo Amarkantak: The Eco Cosmology and Sacred Complex + +16.30 – 17.30 Discussion + +10.00– 10.40: Naran Bilik + +# 28th April + +### Session I + +Chair: Stefano Beggiora + +### Unblocking the Blockage between Earth and Heaven: Shamanism as Cultural Intimacy in China diff --git a/outputs/multi_column/0e1cdcf74d42cf251ad3e6127439c537599c_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/0e1cdcf74d42cf251ad3e6127439c537599c_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..beb7e21de7a877ff4fe94271c652491be26a1541 --- /dev/null +++ b/outputs/multi_column/0e1cdcf74d42cf251ad3e6127439c537599c_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,41 @@ +(ii) The Referee calculates cR \(=[_{\text{AR}}<_{\text{RB}}\in\{0;1\}\) and sends it to Bob (1 bit). + +(iii) After reception of jA, Bob calculates = sign[sin(B - jA 4) and 0B = (B - jA 4 mod) \(\in\) [0; [. He determines the index jB = b4 0Bc \(\in\{0;1;2;3\}\) of the sector where his angle 0B lies, and the bit cB = [RB < 0B - jB 4 \(\in\{0;1\}\). Depending on jB, cA, cR, cB, 0B and RB, he outputs b = with probability }jBcAcRcB(0B - RB), and b = - with probability 1 - }jBcAcRcB(0B - RB), for the functions }jBcAcRcB defined in Table I. + +As explicitly shown in the Supplemental Material [36], the above protocol gives the desired probability P(a=b|A;B)=sin(A-2B)2 for all possible equatorial measurements, using 4 bits of communication. It can then be extended in the following way to all measurement directions on the Bloch sphere, using a similar technique as in [10]: Protocol 2.—For measurement directions x = (sinA cosA; sinA sinA; cosA) and y = (sinB cosB; sinB sinB;cosB), the three parties + +(i) run Protocol 1 with input angles A and B; Alice and Bob obtain intermediate outputs a0 and b0. + +(ii) run Protocol 1 a second time (using a new set of in dependent variables AR, RB), now with input angles a0A and -b0B; Alice and Bob output the outcomes a and b of this second run of Protocol 1. + +This second protocol now simulates the desired correlation E(x; y) = -x - y for all possible projective measurements by Alice and Bob, with 8 bits of communication; for more details on the calculations, see Supplemental Material. Note that Protocols 1 and 2 do not simulate the correct marginals. In order to randomize the marginals, Alice can—at the very end of the protocol—generate a random bit and send it to Bob; depending on the value of this bit, they will both flip their outcomes or not. All in all, the entanglement swapping correlations can thus be simulated with 9 bits of communication. Discussion.—We thus have proved that remarkably, the entanglement swapping process can be simulated with bounded communication, even in a bilocal scenario where Alice and Bob are (as in the quantum case) completely uncorrelated before the protocol is run, and therefore do not have any prior shared randomness. Our protocol provides an upper bound on the nonlocality of entanglement swapping in terms of its communication cost. It is an open question whether fewer bits of communication are actually sufficient: it might indeed be possible to simulate equatorial measurements more efficiently than with Protocol 1, or to find a more direct protocol that does not treat separately the azimuth and zenith angles of the measurement settings, more in the spirit of the Toner-Bacon simulation protocol for singlet correlations [13]. Next, it is natural to consider the simulation of multistage entanglement swapping, which is essential for long + +distance quantum communication. Now, N referees (R1; R2; . . . ; RN) are placed on a line between Alice and Bob. Two neighboring referees share a singlet state, while R1 and RN share singlet states with A and B, respectively; each referee performs a joint measurement, leaving at the end the particles of Alice and Bob entangled. Whereas the quantum protocol has a straightforward and nice iterative character, we were not able to find a simulation protocol with a finite amount of communication in a (N + 1)locality scenario [29]. Consider for instance the case with one additional referee R2. Analogously to our Protocol 1, assume that Alice and R1 share the random variable AR1, R1 and R2 share R1R2, and R2 and Bob share R2B, all uniformly and independently distributed on some interval \([0, \frac{}{\mathrm{m}} ]\). After some finite communication, Bob could for instance [as in our first attempt, before Eq. (3)] output b = a = 1 if and only if [A < AR1 = [AR1 < R1R2 = [R1R2 < R2B = [R2B < B. This would result in the probability P(a \(=\mathrm{b}|_{\mathrm{A}};_{\mathrm{B}}\in[0; \frac{}{\mathrm{m}} )= \frac{\mathrm{m}^{3}}{6^{3}} |_{\mathrm{A}}-_{\mathrm{B}}|^{3}\), which scales cubically with A-B, and is therefore too small when A is close to B. It is unclear how to change the cubic scaling with finite communication. The following questions remain open: can multistage entanglement swapping be simulated with finite communication? Or can one prove, that above a certain value of N, an infinite amount of communication is necessary? We thank Jean-Daniel Bancal, Yeong-Cherng Liang, Stefano Pironio, Tim Räz, and Ronald de Wolf for discussions. This work was supported by a UQ Postdoctoral Research Fellowship, the NSF grant CCF-0832787, the UK EPSRC, the EU DIQIP, the EU FP7 grant project 255961 QCS, Canada’s NSERC and CIFAR, the Swiss NCCR-QSIT, the US ARO, and the European ERC-AG QORE. + +[1] J. S. Bell, Physics (Long Island City, N.Y.) 1, 195 (1964). + +[2] D. Salart, A. Baas, C. Branciard, N. Gisin, and H. Zbinden, Nature (London) 454, 861 (2008). + +[3] H. Buhrman, R. Cleve, S. Massar, and R. de Wolf, Rev. Mod. Phys. 82, 665 (2010). + +[4] A. Ekert, Phys. Rev. Lett. 67, 661 (1991). + +[5] J. Barrett, L. Hardy, and A. Kent, Phys. Rev. Lett. 95, 10503 (2005). + +[6] A. Aćın et al., Phys. Rev. Lett. 98, 230501 (2007). + +[7] S. Pironio et al., Nature (London) 464, 1021 (2010). + +[8] R. Colbeck and A. Kent, J. Phys. A 44, 095305 (2011). + +[9] T. Maudlin, Proceedings of the Biennial Meeting of the Philosophy of Science Association 1992, 404 (1992). + +[10] G. Brassard, R. Cleve, and A. Tapp, Phys. Rev. Lett. 83, 1874 (1999). + +[11] B. Gisin and N. Gisin, Phys. Lett. A 260, 323 (1999). + +[12] M. Steiner, Phys. Lett. A 270, 239 (2000). + +[13] B. Toner and D. Bacon, Phys. Rev. Lett. 91, 187904 (2003). + +[14] S. Pironio, Phys. Rev. A 68, 062102 (2003). diff --git a/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_3_pg1_pg1_repeat1.md b/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_3_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..50c6a3de90bee8c655ff1ad5503c6ed561c9d4ec --- /dev/null +++ b/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_3_pg1_pg1_repeat1.md @@ -0,0 +1,75 @@ +![](figure) + +# GEOL 4006: Topics in Geological Sciences-Mathematical Science + +Organized study of selected topics. Subjects and earnable credit may vary. May be repeated with departmental consent. + +Credit Hour: 1-99 Prerequisites: instructor's consent + +# GEOL 4007: Topics in Geological Sciences-Physical Science + +Organized study of selected topics. Subjects and earnable credit may vary. May be repeated with departmental consent. + +Credit Hour: 1-99 Prerequisites: instructor's consent + +# GEOL 4100: Groundwater Hydrology + +(cross-leveled with GEOL 7100). Analysis of groundwater occurrence, flow, recovery, and solute transport within shallow levels of the Earth's crust. + +Prerequisites: GEOL 1100 or GEOL 2130 or GEOL 1200, and PHYSCS 1210 or PHYSCS 2750, and MATH 1400 or MATH 1500 + +# GEOL 4120: Engineering Geology + +(cross-leveled with GEOL 7120). Fundamentals of earth materials and geological processes and their applications in engineering works and environmental sciences. Includes properties of minerals and rocks, rock and soil mechanics, surficial geological processes, and practice of engineering. + +Prerequisites: GEOL 1100 or GEOL 2130 or GEOL 1200, and MATH 1500, or instructor's consent + +# GEOL 4130: Groundwater Modeling + +(cross-leveled with GEOL 7130). Use of leading groundwater flow and contamination modeling software. Theory of groundwater flow, solute transport, and selected numerical solution techniques. Applications to water resource, environmental, and geological problems. + +Credit Hours: 3 Prerequisites: GEOL 4100 or equivalent + +# GEOL 4150: Structural Geology + +(cross-leveled with GEOL 7150). The mechanical behavior of earth materials. Analysis of the geometry and mechanics of faults, fractures, and folds. Laboratory includes problems on stresses and strains associated with deformation, geometric analysis of deformation structures, and interpretation of geologic maps. + +## Credit Hours: 4 + +Prerequisites: GEOL 1100 or GEOL 2130 or GEOL 1200 and MATH 1140 or MATH 1160 or MATH 1500 + +# GEOL 4180: Solar System Science + +(same as PHYSCS 4180, ASTRON 4180; cross-leveled with GEOL 7180). Investigates physical states, interior structures and comparative geology of solar systems bodies: planets, moons, asteroids, comets, sun. Solar system formation and evolution. + +Prerequisites: MATH 1700 and PHYSCS 1220 or PHYSCS 2760 or instructor's consent + +# GEOL 4200: Economic Geology with Laboratory + +Geochemistry of ore deposits. Introduction to types of mineral deposits, genesis of ore, and current areas of research. Laboratory emphasizes hand-specimen and polished-section studies of a wide variety of ore deposit types. + +Credit Hours: 4 Prerequisites: GEOL 4900 + +# GEOL 4300: Introduction to Low-Temperature Geochemistry + +Introduction to the chemical alteration of rock-forming minerals in weathering environments and to factors controlling the chemical composition of subsurface water. + +Credit Hours: 3 Prerequisites: GEOL 3300 or instructor's consent + +# GEOL 4318: Environmental Soil Chemistry + +(same as SOIL 4318 and ENV_SC 4318; cross-leveled with GEOL 7318, SOIL 7318, ENV_SC 7318). Study of chemical constituents and processes occurring in soils. Topics include soil minerals and weathering processes, organic matter, solution chemistry, oxidation-reduction reactions and adsorption processes. + +Prerequisites: SOIL 2100 or GEOL 2400, CHEM 1320 and CHEM 1330. Junior standing or instructor's consent + +# GEOL 4350: Taphonomy + +(cross-leveled with GEOL 7350). The purposes of this course are to + +1) analyze patterns in the history of life and 2) to recognize the biased processes that led to its preservation. We will accomplish these goals by examining two disparate fossil preservation pathways: 1) Konservat lagerstätten: fossil deposits that are notorious for the exceptional and rare preservation of soft tissues and 2) Konzentrat lagerstätten: fossil deposits that are exceptional for the enormous amount of fossilized skeletal material they contain. Through careful examination of both the rare and the hyper-abundant, we can address the fundamental question of paleobiology: how literally can the fossil record be read as the history of life? Graded on A-F basis only. + +Credit Hours: 3 Prerequisites: GEOL 2350, GEOL 2360 + +# GEOL 4370: Conservation Paleobiology + +(cross-leveled with GEOL 7370). Humans are having an undeniable influence on Earth systems, including the biosphere. Climate change, habitat destruction, over-hunting/harvesting, pollution, and invasive species are among the primary stressors of modern biodiversity. How have ecosystems responded to such stressors in the past? How do we determine what a "pristine" ecosystem looks like when planning ecosystem restoration? Paleontologists are uniquely equipped to address these questions using the fossil record. In this course we will review the important questions in this emerging discipline, learn about the tools used to address these questions, and learn from case studies involving invertebrate, vertebrate, and plant fossils from a variety of environments. diff --git a/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3b4f047617ff8cd77dd5efe8827947f27e6463f1 --- /dev/null +++ b/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,89 @@ +![](figure) + +# GEOL 4500: Organic Geochemistry + +(cross-leveled with GEOL 7500). Topics include chemistry of petroleum-forming reactions and their kinetic parameters; use of organic-chemical criteria in source-rock evaluation; carbon isotope fractionation in organic precursors of biological molecules; early history of earth's atmosphere. + +Credit Hours: 3 Prerequisites: instructor's consent + +# GEOL 4650: Plate Tectonics + +(cross-leveled with GEOL 7650). Formation, evolution, and structure of the earth. Rules, causes, and implications of plate tectonics with emphasis on present-day features. + +Credit Hours: 3 Prerequisites: GEOL 3250 or GEOL 4150 or instructor's consent + +# GEOL 4650W: Plate Tectonics - Writing Intensive + +Formation, evolution, and structure of the earth. Rules, causes, and implications of plate tectonics with emphasis on present-day features. + +Credit Hours: 3 Prerequisites: GEOL 3250 or GEOL 3650 or instructor's consent + +# GEOL 4680: Neotectonics and Earthquake Geology + +(cross-leveled with GEOL 7680). Introduction to techniques and concepts of active crustal deformation from the geological and geodetic perspectives. Topics include tectonic geomorphology, paleoseismology, Quaternary dating, tectonic geodesy, numerical models of faults, and earthquake hazard assessment. + +Credit Hours: 3 Prerequisites: GEOL 3650 or GEOL 4650 + +# GEOL 4750: Microanalysis for Geological Sciences + +(cross-leveled with GEOL 7750). This course is intended to provide a working knowledge of electron and X-ray microbeam analytical instruments - both in principle and in practice. Lectures will focus on the physics of how these instruments collect data, and how these data can be interpreted. In addition, students will gain hands-on experience with operating these instruments, specifically on their own samples, as well as preparing their samples for microanalysis and interpreting/manipulating the resulting data. Graded on A-F basis only. + +## Credit Hours: 3 + +Prerequisites: Instructor's Consent (instrument time is limited so enrollment must also be limited) + +# GEOL 4800: Introduction to Geophysics + +(cross-leveled with GEOL 7800). Introduction to the fundamentals of geophysical methods and their applications in geology, environmental studies, and exploration. Topics include seismic, gravity, magnetic, and electric methods. + +Credit Hours: 3 Prerequisites: GEOL 1100 or GEOL 2130 or GEOL 1200 and MATH 1700 or instructor's consent + +# GEOL 4900: Igneous and Metamorphic Petrology with Laboratory + +Introduction to igneous and metamorphic rock associations and rock-forming processes. Emphasis on understanding the evolution of the Earth in view of igneous and metamorphic rock petrogenesis. + +Credit Hours: 4 Prerequisites: GEOL 3250 Recommended: GEOL 3300 + +# GEOL 4950: Senior Thesis + +Research conducted in an area of the Geological Sciences under the auspices of a member of the faculty. Under normal circumstances, this research should be completed over two semesters. May be repeated for a maximum of 3 hours credit. + +## Credit Hour: 1-3 + +# GEOL 4992: Geology Field Camp + +Field study of sedimentary, igneous and metamorphic rocks. Facies analysis of sedimentary rocks, mapping of folded and faulted sedimentary strata and fabric analysis of an igneous-metamorphic terrane. Excursion to Yellowstone and Grand Teton National Parks. + +Credit Hours: 6 Recommended: GEOL 2350, GEOL 4150, and GEOL 3800 + +## GEOL 7002: Topics in Geological Sciences-Biological/Physical/ Mathematics + +Organized study of selected topics. Subjects and earnable credit may vary. May be repeated with departmental consent. + +Credit Hour: 1-99 Prerequisites: instructor's consent + +## GEOL 7085: Problems in Geological Sciences + +Credit Hour: 1-8 + +Prerequisites: instructor's consent + +# GEOL 7100: Groundwater Hydrology + +(cross-leveled with GEOL 4100). Analysis of groundwater occurrence, flow, recovery, and solute transport within shallow levels of the Earth's crust. + +## Credit Hours: 3 + +Prerequisites: GEOL 1100 or GEOL 2130 or GEOL 1200, and PHYSCS 1210 or PHYSCS 2750, and MATH 1400 or MATH 1500 + +# GEOL 7120: Engineering Geology + +(cross-leveled with GEOL 4120). Fundamentals of earth materials and geological processes and their applications in engineering works and environmental sciences. Includes properties of minerals and rocks, rock and soil mechanics, surficial geological processes, and practice of engineering. + +## Credit Hours: 3 + +Prerequisites: GEOL 1100 or GEOL 2130 or GEOL 1200 and MATH 1500, or instructor's consent + +# GEOL 7130: Groundwater Modeling + +(cross-leveled with GEOL 4130). Use of leading groundwater flow and contamination modeling software. Theory of groundwater flow, solute diff --git a/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_5_pg1_pg1_repeat1.md b/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_5_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..26e60e60c44da224183bf4ae9482ff523cb041cc --- /dev/null +++ b/outputs/multi_column/0e55e3b633484f27fbc4c179795f23d49ce6_page_5_pg1_pg1_repeat1.md @@ -0,0 +1,79 @@ +![](figure) + +transport, and selected numerical solution techniques. Applications to water resource, environmental, and geological problems. + +Credit Hours: 3 Prerequisites: GEOL 4100 or equivalent + +# GEOL 7150: Structural Geology + +(cross-leveled with GEOL 4150) The mechanical behavior of earth materials. Analysis of the geometry and mechanics of faults, fractures, and folds. Laboratory includes problems on stresses and strains associated with deformation, geometric analysis of deformation structures, and interpretation of geologic maps. + +## Credit Hours: 4 + +Prerequisites: instructor's consent and GEOL 1100 or GEOL 2130 or GEOL 1200 and MATH 1140 or MATH 1160 or MATH 1500 + +# GEOL 7180: Solar System Science + +(same as PHYSCS 7180 and ASTRON 7180). Investigates physical states, interior structures and comparative geology of solar systems bodies: planets, moons, asteroids, comets, sun. Solar system formation and evolution. + +## Credit Hours: 3 + +Prerequisites: MATH 1700 and PHYSCS 1220 or PHYSCS 2760 or instructor's consent + +# GEOL 7200: Economic Geology with Laboratory + +Geochemistry of ore deposits. Introduction to types of mineral deposits, genesis of ore, and current areas of research. Laboratory emphasizes hand-specimen and polished-section studies of a wide variety of ore deposit types. + +Credit Hours: 4 Prerequisites: GEOL 4900 + +# GEOL 7300: Introduction to Low-Temperature Geochemistry + +Introduction to the chemical alteration of rock-forming minerals in weathering environments and to factors controlling the chemical composition of subsurface water. + +Credit Hours: 3 Prerequisites: GEOL 3300 or instructor's consent + +# GEOL 7318: Environmental Soil Chemistry + +(same as SOIL 7318 and ENV_SC 7318; cross-leveled with GEOL 4318, SOIL 4318, ENV_SC 4318). Study of chemical constituents and processes occurring in soils. Topics include soil minerals, and weathering processes organic matter, solution chemistry, oxidation-reduction reactions and adsorption processes. + +## Credit Hours: 3 + +Prerequisites: SOIL 2100 or GEOL 2400, CHEM 1320 and CHEM 1330 or instructor's consent + +# GEOL 7350: Taphonomy + +(cross-leveled with GEOL 4350). The purposes of this course are to + +1) analyze patterns in the history of life and 2) to recognize the biased processes that led to its preservation. We will accomplish these goals by examining two disparate fossil preservation pathways: 1) Konservat lagerstätten: fossil deposits that are notorious for the exceptional and rare preservation of soft tissues and 2) Konzentrat lagerstätten: fossil deposits that are exceptional for the enormous amount of fossilized skeletal material they contain. Through careful examination of both the rare and hyper-abundant we can address the fundamental question of paleobiology: how literally can the fossil record be read as the history of life? Graded on A-F basis only. + +## Credit Hours: 3 + +# GEOL 7370: Conservation Paleobiology + +(cross-leveled with GEOL 4370). Humans are having an undeniable influence on Earth systems, including the biosphere. Climate change, habitat destruction, over-hunting/harvesting, pollution, and invasive species are among the primary stressors of modern biodiversity. How have ecosystems responded to such stressors in the past? How do we determine what a "pristine" ecosystem looks like when planning ecosystem restoration? Paleontologists are uniquely equipped to address these questions using the fossil record. In this course we will review the important questions in this emerging discipline, learn about the tools used to address these questions, and learn from case studies involving invertebrate, vertebrate, and plant fossils from a variety of environments. + +## Credit Hours: 3 + +# GEOL 7500: Organic Geochemistry + +(cross-leveled with GEOL 4500). Topics include chemistry of petroleum-forming reactions and their kinetic parameters; use of organic-chemical criteria in source-rock evaluation; carbon isotope fractionation in organic precursors of biological molecules; early history of earth's atmosphere. + +Credit Hours: 3 Prerequisites: instructor's consent + +# GEOL 7650: Plate Tectonics + +(cross-leveled with GEOL 4650). Formation, evolution, and structure of the earth. Rules, causes, and implications of plate tectonics with emphasis on present-day features. + +Credit Hours: 3 Prerequisites: GEOL 3250, GEOL 3650 or instructor's consent + +# GEOL 7680: Neotectonics and Earthquake Geology + +(cross-leveled with GEOL 4680). Introduction to techniques and concepts of active crustal deformation from the geological and geodetic perspectives. Topics include tectonic geomorphology, paleseismology, Quarternary dating, tectonic geodesy, numerical models of faults, and earthquake hazard assessment. + +Credit Hours: 3 Prerequisites: GEOL 4150 or GEOL 4650 + +# GEOL 7700: Theoretical Geochemistry + +Introduction to theoretical concepts in low and high temperature geochemistry. Topics include thermodynamics of fluids, gases and solids in geological materials, phase diagrams, equilibrium constants, electrolyte theory, oxidation-reduction reactions. + +Credit Hours: 3 Prerequisites: GEOL 3250, CHEM 1330 and MATH 1700 diff --git a/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_1_pg1_pg1_repeat1.md b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_1_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..47e9577951104ba6c0898e7c0cbeef4de464aa17 --- /dev/null +++ b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_1_pg1_pg1_repeat1.md @@ -0,0 +1,15 @@ +# Serum Potassium and Outcomes in CKD: Insights from the RRI-CKD Cohort Study + +Sonal Korgaonkar,* Anca Tilea,† Brenda W. Gillespie,† Margaret Kiser,‡ George Eisele,§ Fredric Finkelstein, Peter Kotanko,¶ Bertram Pitt,** and Rajiv Saran*† *Department of Internal Medicine, †Kidney Epidemiology and Cost Center, and **Department of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan; ‡Department of Medicine, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina; §Department of Medicine, Medical College of Albany, Albany, New York; Metabolism Associates, New Haven, Connecticut; and ¶Renal Research Institute, New York, New York + +Background and objectives: The relationship between serum potassium (SK) and mortality in chronic kidney disease (CKD) has not been systematically investigated. Design, setting, participants, & measurements: We examined the predictors and mortality association of SK in the Renal Research Institute CKD Study cohort, wherein 820 patients with CKD were prospectively followed at four US centers for an average of 2.6 years. Predictors of SK were investigated using linear and repeated measures regression models. Associations between SK and mortality, the outcomes of ESRD, and cardiovascular events in time-dependent Cox models were examined. Results: The mean age was 60.5 years, 80% were white, 90% had hypertension, 36% had diabetes, the average estimated GFR was 25.4 ml/min per 1.73 m2, and mean baseline SK was 4.6 mmol/L. Higher SK was associated with male gender, lower estimated GFR and serum bicarbonate, absence of diuretic and calcium channel blocker use, diabetes, and use of angiotensin-converting enzyme inhibitors and/or statins. A U-shaped relationship between SK and mortality was observed, with mortality risk significantly greater at SK <4.0 mmol/L compared with 4.0 to 5.5 mmol/L. Risk for ESRD was elevated at SK <4 mmol/L in SK categorical models. Only the composite of cardiovascular events or death as an outcome was associated with higher SK (>5.5). Conclusions: Although clinical practice usually emphasizes greater attention to elevated SK in the setting of CKD, our results suggest that patients who have CKD and low or even low-normal SK are at higher risk for dying than those with mild to moderate hyperkalemia. Clin J Am Soc Nephrol 5: 762–769, 2010. doi: 10.2215/CJN.05850809 + +Hyperkalemia (serum potassium \([S_{K}]5.5\) mmol/L) is common in patients with ESRD. In the dialysis population, the prevalence of hyperkalemia has been estimated to range from 5 to 10% (1). Hyperkalemia is thought to contribute to 2 to 5% of deaths among patients with ESRD and accounts for up to 24% of emergency hemodialysis sessions in this population (2–4). Hyperkalemia has also been associated with increased mortality (up to 17%) in the general hospitalized population (5). Although nephron adaptation occurs in those with progressive renal insufficiency by way of enhanced distal tubular secretion of ingested potassium (6), mildly elevated potassium levels are not uncommon and dietary restriction of potassium is frequently considered prudent for patients with advanced chronic kidney disease (CKD) to avoid dangerous hyperkalemia (7). Adverse effects of SK \(3.5\) mmol/L have been well documented in the cardiovascular literature. Among patients with heart failure, hypokalemia is associated with ventricular arrhythmias and death (8); however, little is known about adverse effects of hypokalemia in the CKD population, which is known to be at high risk for cardiovascular disease in general and sudden death in particular (9). We postulated that lower \((3.5\) mmol/L) levels of SK would be associated with higher risk for mortality in a CKD population. The aims of this study were to examine the distribution and predictors of SK and association, if any, of SK with mortality, ESRD, the composite outcome of death or ESRD, and the composite of death or any cardiovascular event in a CKD cohort. + +### Materials and Methods + +Data Source: The Renal Research Institute CKD Study This prospective observational study of adult patients with stages 3 through 5 CKD was conducted at four outpatient nephrology clinics in the United States. Patients were recruited between June 2000 and + +Published online ahead of print. Publication date available at www.cjasn.org. February 2006. The inclusion criteria were age \(18\) years and a creat- + +Correspondence: Dr. Rajiv Saran, Department of Medicine, Division of Nephrology, Department of Internal Medicine, Kidney Epidemiology and Cost Center, inine clearance of \(50\) ml/min by the Cockcroft-Gault formula, although subsequently estimated GFR (eGFR) values that were recalculated by the four-variable Modification of Diet in Renal Disease (MDRD) equation were occasionally \(50\) ml/min per 1.73 m2. A total diff --git a/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_2_pg1_pg1_repeat1.md b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_2_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..29b8de596ad46d27b1ac590e2011cf62ac6bff44 --- /dev/null +++ b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_2_pg1_pg1_repeat1.md @@ -0,0 +1,304 @@ +of 834 patients enrolled in the study. Patients were followed by the study coordinators whenever they presented for routine clinical care to their nephrology clinics. The institutional review boards at all participating sites approved the study, and all patients provided written informed consent. Details of the study design have been published previously (10). + +## Study Variables + +At enrollment and follow-up visits, data on demographic, anthropometric, cause of CKD, comorbidities, laboratory variables, medications, and outcomes (ESRD, death, and cardiovascular events/procedures) were collected. Of 834 patients, 820 had SK values available at study entry and were included in the analyses. SK values that were obtained from baseline and subsequent clinic visits were classified into the following categories: \(4.0\), 4.0 to 5.5, and \(5.5\) mmol/L. + +## Statistical Analysis + +Linear regression models were used to assess predictors of SK at baseline, with the adjusted R2 used to compare models in an all-subsets regression analysis. The distributions of SK values was illustrated using box plots by eGFR, gender, angiotensin-converting enzyme inhibitor (ACEI) use and quartiles of serum carbon dioxide (CO2), using all available SK values during follow-up time. The SAS mixed procedure (SAS Institute, Cary, NC) was used to test for differences in SK values between groups. To predict SK during follow-up time, we used mixed linear regression models with a spatial anisotropic exponential covariance structure (to account for correlation between follow-up visits of differing intervals). Separate Cox models evaluated the associations between SK (as a continuous or as a categorical covariate) and time to death, time to ESRD, the composite outcome of death or ESRD, the composite of death or any cardiovascular event (defined as prespecified coronary disease–, cerebrovascular disease–, or peripheral vascular + +Table 1. Patient demographics, comorbidities, medication use, and laboratory variables by serum potassium + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
categories at enrollment
OverallHypokalemiaEukalemiaHyperkalemia
VariableP
(n 820)(n 122)(n 633)(n 65)
Demographics
age (years; mean SD)60.5 15.460.6 16.160.7 15.458.4 14.00.499
male (n %)448 (55)52 (43)346 (55)50 (77)0.0001
black (n %)167 (20)37 (30)117 (19)13 (20)0.012
Vital signs (mean SD)
BMI (kg/m2)29.4 6.929.8 6.929.3 6.929.4 7.70.847
SBP (mmHg)139.7 21.7142.8 23.9139.4 21.6137.8 18.80.211
eGFR (ml/min per 1.73 m2)25.4 10.627.0 13.725.3 9.923.2 10.10.059
Cause of CKD (n %)
diabetes265 (32)39 (32)199 (32)27 (42)0.262
hypertension402 (49)60 (49)310 (49)32 (49)0.99
Medication use (yes/no; n %)
ACEIs332 (41)34 (28)260 (41)43 (66)0.0001
ARBs144 (17)35 (29)144 (23)7 (11)0.021
aspirin304 (37)41 (34)236 (37)27 (42)0.549
blockers392 (47)62 (51)295 (47)35 (54)0.414
calcium channel blocker353 (43)64 (52)294 (46)23 (35)0.083
diuretics409 (50)75 (61)317 (50)34 (52)0.069
erythropoietin199 (24)30 (25)150 (24)19 (29)0.609
statins352 (42)39 (32)278 (44)34 (52)0.014
Laboratory (mean SD)
serum albumin (g/dl)3.8 0.53.7 0.53.8 0.53.7 0.50.098
serum CO2 (mEq/L)24.2 3.926.2 3.724.1 3.821.2 3.50.0001
serum potassium (mmol/L)4.6 0.93.7 0.34.7 0.45.8 0.30.0001
serum phosphorus (mg/dl)4.2 1.14.3 1.54.1 1.04.5 1.10.031
Patient outcomes (n %)
death86 (10)16 (13)64 (10)6 (9)0.576
ESRD303 (36)57 (36)213 (35)33 (48)0.145
coronary artery disease7011 (9)50 (8)9 (14)0.258
cardiovascular disease508 (7)38 (6)4 (6)0.977
peripheral arterial disease708 (7)55 (8)7 (11)0.581
any cardiovascular event19032 (27)139 (22)19 (29)0.249
+ +Hypokalemia: SK \(4.0\) mmol/L; eukalemia: SK \(4.0\text{and}5.5\) mmol/L; hyperkalemia: SK \(5.5\) mmol/L. ARB, angiotensin II receptor blocker; BMI, body mass index; SBP, systolic BP. diff --git a/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_4_pg1_pg1_repeat1.md b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_4_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1cf9e1a2b31b3cb41141fd5dffc75c42e823b635 --- /dev/null +++ b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_4_pg1_pg1_repeat1.md @@ -0,0 +1,23 @@ +Table 2. Predictors of SK at baseline and during follow-up + +| Predictors | | Predictors of SK at Baseline (n 729)a | | Predictors of SK over Time (n 5111)b | +| --- | --- | --- | --- | --- | +| | Estimate | P | Estimate | P | +| Male gender | 0.18 | 0.0001 | 0.18 | 0.0001 | +| Serum CO2 (mEq/L) | -0.05 | 0.0001 | -0.03 | 0.0001 | +| eGFR (per 10 ml/min per 1.73 m2) | -0.02 | 0.39 | -0.06 | 0.0001 | +| Diabetes | 0.10 | 0.029 | 0.06 | 0.030 | +| ACEI use | 0.21 | 0.0001 | 0.17 | 0.0001 | +| Diuretic use | -0.07 | 0.76 | -0.12 | 0.0001 | +| Calcium channel blocker use | -0.06 | 0.12 | -0.09 | 0.0001 | +| Statin use | 0.11 | 0.001 | 0.12 | 0.0001 | + +All variables from Table 1 were tested in the selection models, with significant variables retained \((0.05)\). + +aAll variables simultaneously entered in a multiple linear regression model. bAll variables simultaneously entered in a repeated measures regression model. The values of all covariates (except gender) were allowed to change with follow-up time. + +For the composite outcome of death or ESRD (Figure 3c), a U-shaped relationship between SK and the composite outcome was evident. There was a significantly higher hazard for death/ ESRD at lower serum SK, the significance of which was attenuated by adjustment for serum albumin in the model. As a categorical variable, lower SK levels remained a significant predictor of the composite outcome before and after adjustment for serum albumin (Table 3). Higher SK was not significantly associated with the composite outcome. A total of 190 cardiovascular events (70 coronary, 50 cerebro-vascular, and 70 peripheral vascular) that required hospitalization were documented during the course of the study. A significant quadratic relationship was seen between SK, and the relative hazard of first cardiovascular event or death (Figure 3d) was noted. Unlike overall mortality, this was statistically significant for SK \(5.5\) mmol/L but not for lower potassium \((4.0\) mmol/L). After addition of serum albumin to the model, higher SK but not lower SK was associated with the composite outcome (Table 3). + +# Discussion + +To the best of our knowledge, this is the first study to investigate systematically the prevalence and mortality associated with SK levels that are obtained during routine clinical practice in a large and diverse nondialysis prospective CKD cohort. Our main finding is that SK level \(4.0\) mmol/L was associated with a higher risk for mortality and ESRD compared with SK between 4.1 and 5.5 mmol/L. These observations are of clinical importance, because most physicians consider SK values of 3.5 to 3.9 mmol/L to be “within normal limits.” Our multivariable analyses show that the lowest risk for mortality was in the SK range of 4.1 to 5.5 mmol/L and that mortality or ESRD risk was not significantly higher even at SK levels of 5.5 to 5.9 mmol/L, a range of SK values that almost always evokes clinical concern with or without intervention (e.g., dietary advice, prescription of loop diuretic, discontinuation of potassium-sparing diuretics). This modest level of hyperkalemia seemed to be well tolerated in this patient population from the perspective of predicting mortality risk. The link between relatively normal or low-normal levels of SK (3.5 to 4.0 mmol/L) and mortality has not been previously documented in the CKD population. This finding is not altogether surprising, however. Low SK levels affect myocardial resting membrane potential, which increases the probability of ventricular arrhythmias and sudden cardiac death (11). Hypokalemia can also predispose patients to developing diastolic dysfunction, digoxin toxicity, and insulin resistance, all of which increase the risk for cardiovascular events and death (12–16). Dietary potassium depletion has been linked to the genesis of hypertension, and supplementation can improve BP control (17–19). Data from the cardiovascular literature suggest that serum potassium levels \(4.0\) mmol/L portend a worse prognosis among those who have a history of heart failure or acute myocardial infarction (20,21). Current American Heart Association/American College of Cardiology guidelines recommend that serum potassium levels be maintained between 4.0 and 5.0 mmol/L in those with chronic heart failure (22). Our study provides observational evidence that necessitates similar guidelines for patients with CKD. Not surprising, diuretic use was associated with lower SK levels in this study. Non–potassium-sparing diuretic use has been linked with increased mortality and hospitalization that can likely be attributed to low SK levels (23). Several case-control studies reported an increased risk for cardiac arrest among patients who received high dosages of thiazide diuretics. This risk was lowered when thiazide therapy was combined with potassium-sparing diuretics (24–26). Because diuretics are very commonly used for volume and BP control in the CKD population and hypokalemia is a frequent complication of this class of medications, these results suggest that clinicians need to monitor SK levels closely and consider using potassium-sparing diuretics and/or potassium supplements in patients who have CKD and are prone to hypokalemia; however, clinical trials will need to be performed before formulating defin- diff --git a/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_7_pg1_pg1_repeat1.md b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_7_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..b0c39851435d10f69a5f8a8896a6497598e59322 --- /dev/null +++ b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_7_pg1_pg1_repeat1.md @@ -0,0 +1,59 @@ +of CKD with availability of serum potassium in the majority of patients at multiple time points during follow-up, permitting analyses with SK as a time-dependent covariate. The long duration of follow-up (median 3 years) and detailed medication data are additional strengths. Certain limitations merit consideration. Data on the dietary intake of potassium and protein was not collected in the Renal Research Institute CKD Study; however, we examined models with and without adjustment for serum albumin, a major marker of nutritional status. The predictive value of SK was slightly attenuated by this adjustment, suggesting that nutritional state may be part of the explanation for the link between low SK and mortality. In this study, death, ESRD, and cardiovascular event information was abstracted by study coordinators primarily from patient charts. It is possible that some events were not detected. The average time from the last SK measure until death was 8.2 months, and the median was 5.8 months; therefore, we do not have values of SK closer to the time of death. The relatively weak association of higher SK with mortality may be the result of dialysis initiation as “rescue” therapy in the face of emergent hyperkalemia and absence of data pertaining to serum potassium just proximate to dialysis initiation among those who reached ESRD. Similarly, the association between higher levels of SK and cardiovascular events may reflect a survivor bias rather than a causal effect, although the latter cannot be excluded. Despite these limitations, the association, particularly at the lower end of the range of potassium levels in this patient population, could more plausibly be causally linked (based on what is known about the adverse effects of low potassium) to adverse outcomes in this and other patient populations. Causal inferences cannot be drawn with certainty, however, in the setting of an observational study such as ours. + +# Conclusions + +Lower SK (even less than or equal to a “normal” level of 4.0 mmol/L) seems to predict mortality to a relatively greater degree compared with the risk associated with SK \(5.5\) mmol/L. This study shows that the levels of SK that are associated with lowest risk for mortality are between 4.1 and 5.5 mmol/L, which suggests that maintaining SK in this range may potentially help optimize survival in patients with CKD. Practice patterns could potentially be adapted to supplement potassium (through dietary modification or pills) and avoid use of loop diuretics whenever possible. The benefits of potassium-sparing diuretics such as aldosterone receptor– blocking agents may be due in part to their ability to “normalize” serum potassium levels. Aldosterone is increasingly recognized to be important in the pathogenesis of CKD (37,38), and mineralocorticoid receptor blockade is an increasing used strategy in lowering proteinuria with the potential of both slowing renal disease progression and lowering mortality. These issues warrant future studies that specifically address the role of potassium supplementation in determining outcomes and study the deliberate optimization of serum potassium levels by use of specific drugs in randomized trials. Overall, our findings suggest that attention should be paid to patients who have CKD and are at the lower ranges of SK as well as those with elevated serum potassium to prevent adverse outcomes such as mortality, ESRD, and cardiovascular events. + +# Acknowledgments + +This study was funded by the Renal Research Institute (New York, NY) and Amgen. R.S. is Principal Investigator and B.W.G. is a Co-Investigator in the Centers for Disease Control and Prevention’s National Chronic Kidney Disease Surveillance Project (MM-1149-0/10). Report contents are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention. The results from this analysis were presented in part as a poster (TH-PO918) at the annual meeting of the American Society Nephrology; Philadelphia, PA; November 2 through 4, 2008. We are grateful to all study coordinators and participating patients at the following study sites: University of Michigan (Ann Arbor, MI), Albany Medical Center (Albany, NY), Metabolism Associates (New Haven, CT), and University of North Carolina, Chapel Hill (Chapel Hill, NC). + +# Disclosures + +None. + +# References + +1. + +Tzamaloukas AH, Avasthi PS: Temporal profile of serum potassium concentration in nondiabetic and diabetic outpatients on chronic dialysis. American J Nephrol 7: 101–109, 1987 + +2. + +Sacchetti A, Stuccio N, Panebianco P, Torres M: ED hemodialysis for treatment of renal failure emergencies. Am J Emerg Med 17: 305–307, 1999 + +3. + +Morduchowicz G, Winkler J, Derazne E, Van Dyk DJ, Wittenberg C, Zabludowski JR, Shohat J, Rosenfeld JB, Boner G: Causes of death in patients with end-stage renal disease treated by dialysis in a center in Israel. Isr J Med Sci 28: 776–779, 1992 + +4. + +Shibata M, Kishi T, Iwata H: Clinical study of complications in dialyzed diabetics. Tohoku J Exp Med 141[Suppl]: 417–425, 1983 + +5. + +Stevens MS, Dunlay RW: Hyperkalemia in hospitalized patients. Int Urol Nephrol 32: 177–180, 2000 + +6. + +Gennari FJ, Segal AS: Hyperkalemia: An adaptive response in chronic renal insufficiency. Kidney Int 62: 1–9, 2002 + +7. + +Musso CG: Potassium metabolism in patients with chronic kidney disease (CKD): Part I—Patients not on dialysis (stages 3–4). Int Urol Nephrol 36: 465–468, 2004 + +8. + +Cleland JG, Dargie HJ, Ford I: Mortality in heart failure: Clinical variables of prognostic value. Br Heart J 58: 572– 582, 1987 + +9. + +Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351: 1296– 1305, 2004 + +10. + +Perlman RL, Kiser M, Finkelstein F, Eisele G, Roys E, Liu L, Burrows-Hudson S, Port F, Messana JM, Bailie G, Rajagopalan S, Saran R: The longitudinal chronic kidney disease study: A prospective cohort study of predialysis renal failure. Semin Dial 16: 418–423, 2003 + +11. + +Schulman M, Narins RG: Hypokalemia and cardiovascular disease. Am J Cardiol 65: 4E–9E, discussion 22E–23E, 1990 diff --git a/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_8_pg1_pg1_repeat1.md b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_8_pg1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..d314a3246927fa134114f08c452b74b99011a4bb --- /dev/null +++ b/outputs/multi_column/0e5f0c3447c4f1335b330d58b5e14d6f15b1_page_8_pg1_pg1_repeat1.md @@ -0,0 +1,95 @@ +12. Reungjui S, Pratipanawatr T, Johnson RJ, Nakagawa T: Do + +thiazides worsen metabolic syndrome and renal disease? The pivotal roles for hyperuricemia and hypokalemia. Curr Opin Nephrol Hypertens 17: 470–476, 2008 + +13. Srivastava TN, Young DB: Impairment of cardiac function + +by moderate potassium depletion. J Card Fail 1: 195–200, 1995 + +14. Meldgaard L, Steiness E, Waldorff S: Time course of + +ouabain uptake in isolated myocardial cells: Dependence on extracellular potassium and calcium concentration. Br J Pharmacol 73: 341–345, 1981 + +15. Steiness E: Diuretics, digitalis and arrhythmias. Acta Med + +Scand 647: 75–78, 1981 + +16. Steiness E: Suppression of renal excretion of digoxin in hypokalemic patients. Clin Pharmacol Ther 23: 511–514, 1978 + +17. Ascherio A, Hennekens C, Willett WC, Sacks F, Rosner B, Manson J, Witteman J, Stampfer MJ: Prospective study of nutritional factors, blood pressure, and hypertension among US women. Hypertension 27: 1065–1072, 1996 + +18. Geleijnse JM, Witteman JC, den Breeijen JH, Hofman A, de + +Jong PT, Pols HA, Grobbee DE: Dietary electrolyte intake and blood pressure in older subjects: The Rotterdam Study. J Hypertens 14: 737–741, 1996 + +19. Whelton PK, He J: Potassium in preventing and treating + +high blood pressure. Semin Nephrol 19: 494–499, 1999 + +20. Hulting J: In-hospital ventricular fibrillation and its relation to serum potassium. Acta Med Scand 647: 109–116, 1981 + +21. Ahmed A, Zannad F, Love TE, Tallaj J, Gheorghiade M, Ekundayo OJ, Pitt B: A propensity-matched study of the association of low serum potassium levels and mortality in chronic heart failure. Eur Heart J 28: 1334–1343, 2007 + +22. Hunt SA: ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure). J Am Coll Cardiol 46: e1– e82, 2005 + +23. Ahmed A, Husain A, Love TE, et al: Heart failure, chronic + +diuretic use, and increase in mortality and hospitalization: An observational study using propensity score methods. Eur Heart J 27: 1431–1439, 2006 + +24. Siscovick DS, Raghunathan TE, Psaty BM, Koepsell TD, Wicklund KG, Lin X, Cobb L, Rautaharju PM, Copass MK, Wagner EH: Diuretic therapy for hypertension and the risk of primary cardiac arrest. N Engl J Med 330: 1852–1857, 1994 + +25. Hoes AW, Grobbee DE, Lubsen J: Sudden cardiac death in + +patients with hypertension: An association with diuretics and beta-blockers? Drug Saf 16: 233–241, 1997 + +26. + +Hoes AW, Grobbee DE, Lubsen J, Man in ’t Veld AJ, van der Does E, Hofman A: Diuretics, beta-blockers, and the risk for sudden cardiac death in hypertensive patients. Ann Intern Med 123: 481–487, 1995 + +27. + +Hene RJ, Boer P, Koomans HA, Mees EJ: Plasma aldosterone concentrations in chronic renal disease. Kidney Int 21: 98–101, 1982 + +28. + +Preston RA, Afshartous D, Garg D, Medrano S, Alonso AB, Rodriguez R: Mechanisms of impaired potassium handling with dual renin-angiotensin-aldosterone blockade in chronic kidney disease. Hypertension 53: 754–760, 2009 + +29. + +Bastl C, Hayslett JP, Binder HJ: Increased large intestinal secretion of potassium in renal insufficiency. Kidney Int 12: 9–16, 1977 + +30. + +Perez GO, Pelleya R, Oster JR, Kem DC, Vaamonde CA: Blunted kaliuresis after an acute potassium load in patients with chronic renal failure. Kidney Int 24: 656–662, 1983 + +31. + +Lush DJ, King JA, Fray JC: Pathophysiology of low renin syndromes: Sites of renal renin secretory impairment and prorenin overexpression. Kidney Int 43: 983–999, 1993 + +32. + +Allon M, Dansby L, Shanklin N: Glucose modulation of the disposal of an acute potassium load in patients with end-stage renal disease. Am J Med 94: 475–482, 1993 + +33. + +Reardon LC, Macpherson DS: Hyperkalemia in outpatients using angiotensin-converting enzyme inhibitors: How much should we worry? Arch Intern Med 158: 26–32, 1998 + +34. + +Jafar TH, Stark PC, Schmid CH, Landa M, Maschio G, de Jong PE, de Zeeuw D, Shahinfar S, Toto R, Levey AS, AIPRD Study Group: Progression of chronic kidney disease: The role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition—A patient-level meta-analysis. Ann Intern Med 139: 244–252, 2003 + +35. + +Schwarz S, Trivedi BK, Kalantar-Zadeh K, Kovesdy CP: Association of disorders in mineral metabolism with progression of chronic kidney disease. Clin J Am Soc Nephrol 1: 825–831, 2006 + +36. + +Nath KA, Hostetter MK, Hostetter TH: Pathophysiology of chronic tubulo-interstitial disease in rats: Interactions of dietary acid load, ammonia, and complement component C3. J Clin Invest 76: 667–675, 1985 + +37. + +Epstein M: Aldosterone blockade: An emerging strategy for abrogating progressive renal disease. Am J Med 119: 912–919, 2006 + +38. + +Bianchi S, Bigazzi R, Campese VM: Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease. Kidney Int 70: 2116– 2123, 2006 diff --git a/outputs/old_scans/10_pg1_repeat1.md b/outputs/old_scans/10_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c92f67a22643437256464207b4cdf931cecf2cae --- /dev/null +++ b/outputs/old_scans/10_pg1_repeat1.md @@ -0,0 +1,23 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +May 22, 1914. + +The Hon. Theodore Roosevelt, +287 Fourth Avenue, +New York City. + +Dear Sir:- + +Indiana County Progressives send you congratulations on your safe return from your epoch-making journey to South America. + +Ours is the Pennsylvania County that gave you six hundred more votes than Taft and Wilson combined received. I hereby make a special plea that you honor us with a campaign speech when you tour Pennsylvania. Indiana, the county-seat, is situated at the center of the county and is entered by rail-roads and trolley-lines leading to different sections. When you come thousands will greet you, and in no uncertain tones. + +Progressivism is a live issue here. We are in the fight to stay. We want no fusion or amalgamation with the Republican party, the party of Penrose and his ilk. + +I am, + +Sincerely, +J. Day Brownlee, Jr. +Chairman of Washington Party in Indiana County, Pa. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/11_pg1_repeat1.md b/outputs/old_scans/11_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..941c2d534d2ed6a7e9ae287c102fad9adaf28f2b --- /dev/null +++ b/outputs/old_scans/11_pg1_repeat1.md @@ -0,0 +1,45 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +FOUNDED 1814. + +Mount Pleasant Academy + +OSSINING-ON-HUDSON + +Charles Frederick Brusie, A. M. (Williams, '87) PRINCIPAL + +ALSO +MOUNT PLEASANT HALL +A SCHOOL FOR YOUNG BOYS + +ack +5/28/14 + +May 22, 1914. + +Col. Theodore Roosevelt, +Oyster Bay, N. Y. + +My dear Col Roosevelt:-- + +You have received a formal invitation from Mount Pleasant Academy to attend its One Hundredth Anniversary. I have been looking forward to this event hoping that you could be present with us on that occasion. + +You will remember, possibly, that in 1903 while Governor, you reviewed our cadets and addressed them, together with the townspeople, from old Junior Hall. All our patrons and alumni have hoped that you might be here. Of course, I understand that your engagement abroad must of necessity have precedence over anything else. We should be glad, however, if we could have an expression of good will from you for this occasion. + +Not many schools have reached the hundredth year mark and we feel that Mount Pleasant Academy has earned a right to honor and consideration. + +We are all glad to welcome you back to this country where your services and your personality are both sincerely appreciated. + +With best wishes for a pleasant and successful + +voyage, I am + +Yours very truly, + +C. F. Brusie + +CFB/HTC. + +C. F. Brusie + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/12_pg1_repeat1.md b/outputs/old_scans/12_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3f852f653fa03fd5024e896c1c59efd8ac45a164 --- /dev/null +++ b/outputs/old_scans/12_pg1_repeat1.md @@ -0,0 +1,13 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +[shorthand notation] + +Hoboken 5-22-14 + +Mrs Theodore Roosevelt + +Dear Madam. + +I know you will forgive the liberty I am taking when I explain my motive. I want Mr Roosevelt to take Warburgs Tincture for his jungle fever, and as I am a married man, take this means of bringing it to his notice. It can be procured of any first class drugstore. I am not in any way connected with the sale of it, and have nothing to gain. Am simply a railroad man, a locomotive engineer, who contracted the Chagres fever while working on + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/13_pg1_repeat1.md b/outputs/old_scans/13_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3b8cb66b8057eeab641e16b3ebe91637f318fb43 --- /dev/null +++ b/outputs/old_scans/13_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +the Panama canal under the French Government and was cured of the fever by Warburg's tincture. I say I have nothing to gain; I have. Would like to think that I had been instrumental in restoring, "Our Teddy," to normal health. + +Very respectfully E P Burgoyne 1205 Washington St Hoboken N J. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/14_pg1_repeat1.md b/outputs/old_scans/14_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..cbe40842896ea5f8e5973a7965e229888f2fc047 --- /dev/null +++ b/outputs/old_scans/14_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +West New Brighton S. I. N. Y. 5-22-14 + +My Dear Col Roosevelt It has added some years to my life to know that you have returned to God's land safe, sane and sound and hope you will regain your health and again come [in] and work out some truths for the people as this land of U.S. needs such minds to guide U.S. hoping for your good health I am yours Sincerely (I ask otherwise John M. Burnett. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/15_pg1_repeat1.md b/outputs/old_scans/15_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0d7ecb8e825c20d4c176199e9a953f1d0d627e3f --- /dev/null +++ b/outputs/old_scans/15_pg1_repeat1.md @@ -0,0 +1,39 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +MARION BUTLER + +J.M. VALE + +BUTLER & VALE +ATTORNEYS AT LAW +SOUTHERN BUILDING +WASHINGTON, D.C. + +10. + +May 22nd, 1914. + +Col. Theo. Roosevelt, +Oyster Bay, L. I. +New York. + +ack +5/26/14 + +Dear Mr. President, + +Confirming my telegram, +Mrs. Butler and I will be delighted to have +you as our guest while you are in Washington +next week, on the occasion of your lecture +before the National Geographical Society. + +Trusting that we will have the +pleasure of entertaining you, and that your +health is being rapidly restored, I am, + +Very sincerely yours, + +Marion Butler + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/16_pg1_repeat1.md b/outputs/old_scans/16_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0c1cd3934ce61f85cf2371d99057b3b1c107f678 --- /dev/null +++ b/outputs/old_scans/16_pg1_repeat1.md @@ -0,0 +1,32 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Ack +5/30/14 + +May 22nd, 1914. + +Col. Theodore Roosevelt, +Oyster Bay, +New York. + +My dear Col. Roosevelt: + +Regarding the three lion rugs which were returned to me for repairing: + +I am enclosing you several photographs of lion head which I have mounted for the wall and with which I have been very successful; several men having sent me their lion rugs to put into this shape. I offer these as a suggestion for the rugs that you have returned, since, after two attempts, it seems impossible to find any way to keep your lion rugs from wrinkling; as I have said before, this is due to the original tanning. + +In mounting these heads for the wall the body skin is not cut away, but tucked inside the head and shoulders. The mounts are much more satisfactory in appearance than the rugs inasmuch as they are more natural, and the main difference is that the skin gets now ware such as it is subject to on the floor. + +I would strongly advise that your rugs be made into similar mounts, and would be very glad to hear from you regarding this. + +I am under the impression that there is something to be fixed on the elephant tusk gong; if this is so, I would be glad to fix it whenever you so desire. + +With congratulations for you recent successful trip and with kindest regards, I am + +Very respectfully yours, + +James L. Clark + +Mrs Roosevelt requests to be lined with canvas + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/17_pg1_repeat1.md b/outputs/old_scans/17_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9890c7076db7dd8f3a55a1edf8fc28012c4b8ff2 --- /dev/null +++ b/outputs/old_scans/17_pg1_repeat1.md @@ -0,0 +1,23 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +ALUMNI FEDERATION OF COLUMBIA UNIVERSITY + +May 22, 1914 + +Hon. Theodore Roosevelt, +Oyster Bay, N. Y. + +My dear Colonel Roosevelt: + +Columbia University conferred upon you in 1899 the degree of LL. D.; therefore, being an honorary graduate of Columbia, you are cordially invited to attend the Alumni Luncheon as a guest of the Alumni Federation on June 3. The Luncheon will be held in the University Gymnasium where one of the Alumni tables will be specially reserved for the honorary graduates, of whom we hope there will be a large gathering. + +We would appreciate your acceptance of this invitation and would ask that you send it at the earliest date, so that a guest ticket for admission to the luncheon may be mailed to you. + +Appreciating your prompt response, I remain, + +Very sincerely yours, + +George Brokaw Compton +Executive Secretary + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/18_pg1_repeat1.md b/outputs/old_scans/18_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..67ff81b6f4564030258bbe0f5d8b4d0e795478bd --- /dev/null +++ b/outputs/old_scans/18_pg1_repeat1.md @@ -0,0 +1,13 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Edward S. Connolly, Agt. 1005 North Main Street Fall River, Mass. + +May 22/14. + +Hon. Theo. Roosevelt. Oyster Bay. + +Dear Sir:— It is surprising to note the feeling of disgust at the present administration and the expressions of regret that you or your like do not happen to be on the job at Washington for the present and for some time past. + +yours truly E. S. Connolly, + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/19_pg1_repeat1.md b/outputs/old_scans/19_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fa0535b70b3e8984c7d26d8be250f705ef6f6bbf --- /dev/null +++ b/outputs/old_scans/19_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Hon. Theodore Roosevelt, Oyster Bay, N. Y. My Dear Honorable: Please pardon the liberty I take in penning you these few lines. I am also enclosing a copy of U. S. Letters patent, that was issued to me Dec. 30th 1913, which is self explanatory. Now what I want to do is this: As I am a poor man, and am not able to finance this proposition; I would like to get an order from you for 10,000, or more, Badge Buttons. The more the better, and a large order such as you might want would enable me to get my proposition on the market. If I can get an order from you for 10,000, Buttons, or more, I will sign you a good contract, to the extent + +JUN 5 ANSD + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/1_pg1_repeat1.md b/outputs/old_scans/1_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..eafde2b77f3637723f57ddc458a6b3212ec65788 --- /dev/null +++ b/outputs/old_scans/1_pg1_repeat1.md @@ -0,0 +1,5 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Bangor. Pa. May 22nd 1914. Col. Rosevelt Comrade & Friend Dear Sir I am one of Gen D. E. Sickles old Regt & Brigade I Served through all of the civil War. During the 5. years was with Gen Sickles when He Loost His Leg. then He Left us. I Regret your Absence From this country During your trip to S. A. I. Saw Mr Pinchott Here & Had a Little talk with Him about you & the Political Situation of the country I am with you for the Election of Gifford Pinchott as U. S. Senitor. One Law Here must Be Repealed. as we are Deprived of Voting for whoever We Desire at the Primaries. if you come to Easton or Bangor Pa I would Like to See you Address 25 Market St Bangor Pa Yours very Resp. Caleb Aber + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/20_pg1_repeat1.md b/outputs/old_scans/20_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..72f0f447a7c092d1dc4090ed8fba5bb5cb1e98fc --- /dev/null +++ b/outputs/old_scans/20_pg1_repeat1.md @@ -0,0 +1,5 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +that I will furnish you these Buttons at factory price plus 1 cent royalty each. I have something new in the Badge Button line. I will have the Eye lithographed on the pl. provided on the front of the button for same. also if you so desire. I will have a Bull moose put on the plane that slides up and down. that causes the Eye to wink when the string is pulled. An order from you for 10,000 Buttons would mean an immediate sale of 1/2 interest in my patent, and that would certainly be highly appreciated I am sure. Why not give me an order for 10,000 Buttons? We can put on any brief witticism, legend or add. you may desire. While I realize that the value of + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/21_pg1_repeat1.md b/outputs/old_scans/21_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fee6e8d092c91252ea00a9948675ed5d855ade5b --- /dev/null +++ b/outputs/old_scans/21_pg1_repeat1.md @@ -0,0 +1,5 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +this device is none; but for advertising purposes it will be very catchy and as you will no doubt put out some kind of campaign advertisement. I was sure like to have part of your business! I wish I could see you in person, and thank you very very much for your kindness, consideration to this rather lengthy letter, and trusting that I may receive from you an early and favorable reply. I am sending under separate cover, a rough model and copy of my patent. I am also enclosing my Baby's picture, the one that I am working for. and the reason I am writing you regarding my novelty is to see if I can't, + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/22_pg1_repeat1.md b/outputs/old_scans/22_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ab6e8af37e8fb6aedced3387b527c6925a87aa78 --- /dev/null +++ b/outputs/old_scans/22_pg1_repeat1.md @@ -0,0 +1,22 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +WESTERN UNION +WESTERN UNION +TELEGRAM +THEO. N. VAIL, PRESIDENT + +RECEIVED AT + +Theo Roosevelt +&c + +Farmington Conn 22 + +5/22/14 + +Will expect you for lunch at Belmont Wednesday any hour you prefer + +Anna Roosevelt Cowles +1124A + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/23_pg1_repeat1.md b/outputs/old_scans/23_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4ce9a8d8475482871b52d05b100cff2cbcffdf23 --- /dev/null +++ b/outputs/old_scans/23_pg1_repeat1.md @@ -0,0 +1,16 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Waldemere +Bridgeport, Connecticut + +Mr. Frank Harper, Sec'y. +To Colonel Theodore Roosevelt, +287 4th Ave., New York City. + +My dear Sir:- + +I am writing you at the suggestion of Mr. Sanford Stoddard of Bridgeport, and Mr. McGraw, Sec'y. at the Progressive Headquarters in New York, to ask your good offices in behalf of the Contemporary Club of Bridgeport, of which I have the honor to be President. + +The Contemporary Club is a literary club of this City, composed of one hundred and twenty-five of the leading gentlemen and ladies + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/24_pg1_repeat1.md b/outputs/old_scans/24_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..25d89176245f1e7424ea090c1df3953178ef4d1f --- /dev/null +++ b/outputs/old_scans/24_pg1_repeat1.md @@ -0,0 +1,24 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +City, and the Club would be glad to pay him any reasonable remuneration within our means. + +Will you kindly let me know at your convenience, if it would be possible to make this arrangement, and what remuneration would be expected? + +Hoping you will take this up with +Colonel Roosevelt at your earliest convenience, +I am, + +Very truly yours, +Lewis B. Curtis +Pres't. + +May twentysecond, +Nineteen hundred and fourteen. + +of this City. They meet at private houses, once a month during the winter, to listen to lectures of distinguished statesmen and artists. In the past President Wilson, Ex-President Taft, and many literary lights have been before us. + +Our next course will open next October, and my object in writing you is to see if it would be possible to induce Colonel Roosevelt to come to Bridgeport, and tell the Club some of his hunting experiences, or any other subject that he would care to talk on. We would like to get him very much for our opening meeting about the tenth of October, but if that was impossible, then some other month later in the season. + +He would be suitably entertained while here by some of the prominent people of the + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/25_pg1_repeat1.md b/outputs/old_scans/25_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e8a58138a548638354001d353861244108e82aad --- /dev/null +++ b/outputs/old_scans/25_pg1_repeat1.md @@ -0,0 +1,32 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +ALL U. S. COURTS AT WASHINGTON. +ALL COURTS OF THE DISTRICT OF +COLUMBIA AND MARYLAND. +U. S. DEPARTMENTS. + +REFERS, BY PERMISSION TO +THE NATIONAL BANK OF WASHINGTON +CABLE ADDRESS: "DLACY" + +LAW OFFICES +WILLIAM H. DELACY +SECOND FLOOR, BARRISTER BUILDING +NO. 635 F STREET N.W. +TELEPHONE, MAIN NO. 8660 +WASHINGTON, D. C. +May 22, 1914. + +ack. 5/27/14 + +Dear Col. Roosevelt:- + +Welcome home! and every good + +luck attend you. + +Sincerely yours, + +Wm H. Delacy + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/26_pg1_repeat1.md b/outputs/old_scans/26_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..83757b6ededce7755fc877b6d50a94e19e057fe2 --- /dev/null +++ b/outputs/old_scans/26_pg1_repeat1.md @@ -0,0 +1,11 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +ISLIP, L. I. May 22 1914 + +Col Theodore Roosevelt Oyster Bay L. I. + +Dear Sir + +So many of your admirers on this side of Long Island, who have for a long time been deprived of the pleasure of hearing you speak, have expressed a strong desire to do I take the liberty to ask if you have an open date in June or July that you could give me for an afternoon address. Islip as you know is a central point in the wealthiest county in the state and I can assure you a large and enthusiastic + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/27_pg1_repeat1.md b/outputs/old_scans/27_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ecbc57ade74f8dab26216a864deb70566c822427 --- /dev/null +++ b/outputs/old_scans/27_pg1_repeat1.md @@ -0,0 +1,11 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Willow Brook Running and Driving Park + +ISLIP, L. I. 191 + +audience. Trusting you will favor my request with your consideration I am + +Respectfully yours Frank J. Dion Pres (Dion) Willow Brook Park Islip L. I. by EG Perkins Secy + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/28_pg1_repeat1.md b/outputs/old_scans/28_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..52aef730143b80535b48709ae3d3e5edc38f2b33 --- /dev/null +++ b/outputs/old_scans/28_pg1_repeat1.md @@ -0,0 +1,22 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Dorchester, Mass., May 22nd., 1914. + +Hon. Theodore Roosevelt, +Oyster Bay. + +Dear sir:- + +The blind gropings of our legislators and men in places of authority to secure an entering wedge for the reduction of the cost of living and remedy existing conditions with relation to monopoly are a joke to some of the workers who are on the inside. + +I know and have full and complete knowledge of the key to the gradual destruction of all food and provision combinations, including all trusts and combinations of bankers, which will invariably be found to exist only by unfair methods of competition, and the elimination of control of legislation by capital. The use of this key will gain its author, or sponsor, grateful memory by the common people for a hundred years. + +Will you make this a campaign issue and the fight of your life with all the forces of capital arrayed against you, but, with the labor organizations and the common people with you? + +Address me at 81 Bernard St. + +Very Respectfully, + +C. A. Eaton. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/29_pg1_repeat1.md b/outputs/old_scans/29_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..99a490a9e6aca7dd3ae2c1a8a265913ad268a4f2 --- /dev/null +++ b/outputs/old_scans/29_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +My Dear Mr. Roosevelt I want to express to you my appreciation of your many and notable services to your country. + +At this time, after having watched you + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/2_pg1_repeat1.md b/outputs/old_scans/2_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..24141f647261b7ad532bea0865dea496d81fe254 --- /dev/null +++ b/outputs/old_scans/2_pg1_repeat1.md @@ -0,0 +1,27 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +INCORPORATED + +INTER-DEPARTMENT +COMMUNICATION + +IN REPLYING PLEASE REFER TO + +REPLYING TO YOUR LETTER OF + +GALVESTON, TEX. MAY 22/1914 + +HON THEO. ROOSEVELT, +OYSTER BAY, N. Y. + +DEAR SIR- + +JUST A LINE OF GOOD WISHES ON YOUR SAFE RETURN, AND THE HOPE THAT YOUR HEALTH MAY BE COMPLETELY RESTORED; EVERY LINE THE NEWSPAPERS PRINT OF YOU AND YOUR ACTIVITIES IS READ WITH AVIDITY. + +A GROUP OF US TELEGRAPH OPERATORS WERE KINDLY DISCUSSING YOU AND YOUR MOVEMENTS THIS MORNING, AND I DECIDED TO SEND THIS LETTER TO SHOW WHAT WE THINK OF "OUR TEDDY" DOWN THIS WAY, AND HOPE YOU MAY SOME TIME HONOR OUR GREAT AND GROWING CITY WITH A VISIT. + +YOURS RESPECTFULLY, + +Robert Lyles Beal + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/30_pg1_repeat1.md b/outputs/old_scans/30_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..debf0ba59ab1f6d05818f409aae40d8d46770c36 --- /dev/null +++ b/outputs/old_scans/30_pg1_repeat1.md @@ -0,0 +1,11 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +indeed strengthened by the proposed change in your formal relation to the Outlook. With this change I am quite sure that we can do more to promote the interests which we both have at heart. We shall want our correspondence, when it is published, to make clear that our interest in and loyalty to the principles for which both you and we have stood, & to you as the leader in this great democratic movement, is unchanged, and that we can still count on you as + +special contributor on social and political topics. + +Of course nothing will be published, nor by us anything said, until you return to America. Meanwhile I shall endeavor to draft a letter in response to yours and get it into Laurence's hands, for consultation between you and him, if, as you have intimated, you return together on the same steamer. + +Believe I pray you in my sincere affection and esteem for you and my faith in what you have so splendidly stood for in our + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/31_pg1_repeat1.md b/outputs/old_scans/31_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..de2e4b5ad7eb89ed78aa596a200fb71aa53c3dc3 --- /dev/null +++ b/outputs/old_scans/31_pg1_repeat1.md @@ -0,0 +1,11 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +I wish I could be on an island somewhere, about ten feet square and speak out. I could tell you just what I think about Mexico. I lived on its border for fifteen years. I speak Spanish indifferently--read it--lived in Spain thirteen months, had a home in Madrid, and should accept the invitation of Ambassador and Mrs, Willard to the wedding breakfast, were it possible. I am one of the men, who is glad that you are going to visit Spain. I do not know your reasons, but I am dead certain that you have got good ones. I am also glad that you have been in South America. I tied that trip up with Root's trip under your administration, and have said once or twice on the public platform, it took four hundred years before these Continents found a man courageous enough to open the way to the East, The dream--Isabella pawned her jewels to help Columbus' adventure. We are in a remarkable position. We are at the parting of the way of our provincial outlook. We must effectually, courageously be the big brother of this Western galaxy of republics. + +There is a great chain of world events coming together here--you have been the leading almost the initial spirit in our Spanish and Southern development. Root sounded a just regret when he asked the country to let the old party open the canal they built. Of course, if it was not for Goethals you might still do that. Spain built a "Silver Fleet" England, the people of the North, colonized, these two points of view are still warring in North America. + +I cannot help but think of General Wood and Goethals when I think of you, and of these things. You do not need Goethals any longer at Panama. I may be wrong, but I cannot but think of him--I cannot think of anyone else for the Governorship of New York next Fall. Mitchell, the State, the City--need him. And Mexico must be put in order by you and General Wood. That job has got to be done and think of having the time, the place and the men. + +Well, Godspeed you on your way. I am sending Kermit a portfolio of photogravures, about thirty-eight of my productions. I shall anxiously watch + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/32_pg1_repeat1.md b/outputs/old_scans/32_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..06a1900e9745da4b76bcb4b14566797dbe2f8953 --- /dev/null +++ b/outputs/old_scans/32_pg1_repeat1.md @@ -0,0 +1,17 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Private and confidential. + +Central College, + +Fayette, Mo + +Jany 1st 1862 + +Hon J Holt. + +Dear Sir. + +Allow me in view of the pleasant relations and recollections of other years and the confidence I have in your high regard for justice right and humanity to invoke your aid in a matter which I will briefly present. Rev. David Fisher residing in this neighborhood a minister of the M. E. Church, South was some months ago arrested by the Military as were nearly all of our ministers. He was required to take the military oath and give heavy bond. Since that time he has been one of our most quiet citizens, keeping himself studiously on his farm, avoiding + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/33_pg1_repeat1.md b/outputs/old_scans/33_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..4fec9fd36c5de76caf978efb1f6736145407122c --- /dev/null +++ b/outputs/old_scans/33_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +carefully reference to our political troubles and attending to his own business. On yesterday to his surprise and to the surprise of all his neighbors, he received an order from Gen Lewis Merrill requiring him to leave the State within fifteen days and take up his residence somewhere in the extreme North. Mr Fisher is an old man, has the respect of those know him, and is a devoted and useful minister. He will leave a feeble wife and young daughters behind him comparatively helpless. I should not suffer my sympathies for him or any other if guilty to interfere with his punishment. But I think here is a grievous wrong to be inflicted upon gray hairs undeserving it, and that too in the name of the Constitution + +and country that we love and venerate. I know that Military Law is harsh and unfeeling. Yet I do not impute in any degree the wisdom or good intentions of those in power. There is a mistake somewhere, and it may be that contraband testimony may be concerned. I do not know I merely state the simple facts as a man of truth. My judgement and my heart are deeply grieved to see wrong done to a lone individual which while it crushes him may result in evil to that very cause proposed to be benefitted by this action. Is there no help in the matter? To whom may an humble individual look for aid. I feel that the Joseph Holt whom I with others loved and + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/34_pg1_repeat1.md b/outputs/old_scans/34_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..901614316f66f2487087009f7ca1eb8f10234def --- /dev/null +++ b/outputs/old_scans/34_pg1_repeat1.md @@ -0,0 +1,5 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +been honored in other years in old Ky will not suffer wrong so fearful to be done if he can prevent it I know not what can be done, or what is best to be done. I throw myself on your superior wisdom, and believe you will do what you can either to have the case reexamined — the punishment suspended or in someway so modified as that it will not work the sad results it must in its present form. Your Ky heart would burn within you could you but know one half of the truth of matters in Mo, and the hostile, deadly effort made to destroy our church, our beloved and cherished Methodism, by insult and abuse of her ministry. And what makes it almost unsupportable is to receive + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/35_pg1_repeat1.md b/outputs/old_scans/35_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c90623e55388130797743d77980c1bcd90a866cb --- /dev/null +++ b/outputs/old_scans/35_pg1_repeat1.md @@ -0,0 +1,9 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +than hinder and embarrass? There might have been a time when this terrorism may have been serviceable, but has not that time past? Is it not unwise to stir up any element that may array thousands of minds and hearts against a scheme they might under a milder reign have been disposed to favor? Excuse me. I have too long intruded upon your time. If it were known that I had written this letter it would at once be determined that it was "interference with military rule," and I should have to suffer the penalty. Yet duty is stronger than fear and justice right and humanity are stronger in their claims than merely personal considerations. + +If my letter is not in place forgive me and let the wife and young daughter of my friend with almost broken hearts plead for justice to a husband — a father — a grey haired minister of Jesus. I say "justice" for it is justice to guard a man from punishment he does not deserve. Do, not if you can let the writer be involved in this matter further than a [desire] wish that that which he would desire to be done to himself under the lights of truth justice and humanity in the same condition may be done to that friend, for whom he pleads. + +Yours very respectfully W. H. Anderson + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/36_pg1_repeat1.md b/outputs/old_scans/36_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..bef2133e6d82eed8a7601026fc1cf83e7d217277 --- /dev/null +++ b/outputs/old_scans/36_pg1_repeat1.md @@ -0,0 +1,55 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +State of the Bank of Kentucky and Branches. +JANUARY 1, 1862. + +RESOURCES. + +Bills of Exchange ..... \$1,613,556.10 +" " Matured and Unpaid ..... 630,210.76 +SIX PER CENT INVESTMENTS, +Viz: Notes Discounted ..... 1,510,568.64 +Matured and Unpaid ..... 173,650.49 +Suspended Debt in suit, Notes and Bills ..... 241,578.38 +126 Bonds of City of Louisville, 6 per cent. cost ..... 94,750.00 +Loan to State of Kentucky ..... 500,000.00 +Stocks and Bonds of other Corporations, &c. ..... 8,317.99 +Real Estate for Debt ..... 67,001.85 +" " and Stocks of Schuylkill Bank ..... 126,685.02 + +2,722,552.37 + +Due from Panks other than Eastern ..... 239,641.52 +Real Estate for Banking Houses ..... 81,250.97 +CASH—Gold and Silver ..... 984,508.97 +Notes of other Banks ..... 166,682.00 +On Deposit in Banks, New York, Phila. & Baltimore ..... 673,081.75 + +1,824,272.72 +\$7,111,484.44 + +LIABILITIES. + +Capital Stock ..... \$3,700,000.00 +Less 226 shares canceled ..... 22,600.00 +\$3,677,400.00 +Surplus—Contingent Fund of 2 per cent. reserved by Charter ..... 74,000.00 +Fund to cover loss by bad debts ..... 76,332.09 +Profit and Loss Balance, after deducting present Dividend ..... 459,148.60 +€09,480.69 +Dividends Uncalled for ..... 7,274.86 +" No. 48, January, 1862, 2 per cent ..... 74,000.00 +81,274.86 +Due to Banks ..... 164,513.21 +" " Depositors and State Treasurer ..... 1,393,083.68 +Circulation ..... 1,185,732.00 +\$7,111,484.44 + +BANK OF KENTUCKY, +LOUISVILLE, JANUARY 1ST, 1862. + +S. H. BULLEN, Cashier. + +NOTE.—The Branches of this Bank at Bowling Green, Hopkinsville, and Columbus, have been for several months within the lines occupied by the army of the Southern Confederacy. We have no satisfactory report of the condition of their Assets, and correspondence with Southern cities being suspended, we are unable to give a satisfactory report of the condition of the paper placed in Southern Banks for collection. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/37_pg1_repeat1.md b/outputs/old_scans/37_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0fa887d303ddee896c330d700cbb9bf82e9ad36a --- /dev/null +++ b/outputs/old_scans/37_pg1_repeat1.md @@ -0,0 +1,15 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +"Content" + +January 3rd Dear friend + +The second session of Mr Hunt's school begins on the 15th of January + +Holt is very much pleased and is, I hope, progressing rapidly. + +I have been looking for that promised visit we have had such beautiful weather this fall. + +The family are well with the exception of our dear Mother whose + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/38_pg1_repeat1.md b/outputs/old_scans/38_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..a68619ce2152ef582b7ad43360d6d0867d5a63ef --- /dev/null +++ b/outputs/old_scans/38_pg1_repeat1.md @@ -0,0 +1,9 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +health is so impaired that either my Sister or myself have to be with her all the time. + +Hoping this may be a very happy year for you and that you may be repaid in part for the many benefits you have bestowed upon others. + +I remain sincerely your friend Julie Schoepf + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/39_pg1_repeat1.md b/outputs/old_scans/39_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0d20ddb263ce86a4eb61fd3c73de769ce2cbd2f3 --- /dev/null +++ b/outputs/old_scans/39_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Washington D. C. Jany 3rd 1862 Judge J Holt. + +Dr Sir You will accept my gratitude for kindness. While in the Capitol of our Sorrowing, bleeding Country. I shall leave to day, for Louisville, Ky to use (though feeble it may be) my influence to give a proper direction, to the legislation of our Native State — I shall leave the consummation of the business on which I visited this City to Yourself & the Hon Samuel L. Casey. Which hope you urge through as fast as practicable and Direct to Me to Care of Dr T. S. Bell Louisville Ky. I would be glad an order could be issued giving Mr J M Shackleford a Special Command including that part of Ky lying North of Cumberland River and South of Ohio — West of line from Clarksville Ten to Owensboro on Ohio River I am Confident The Guerrilla & other raids will be Stoped — + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/3_pg1_repeat1.md b/outputs/old_scans/3_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7bcda9d15b27de9aef6931a52acd557c6a08cdd3 --- /dev/null +++ b/outputs/old_scans/3_pg1_repeat1.md @@ -0,0 +1,23 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +THE BECKNER PRINTING COMPANY + +“WE NEVER DISAPPOINT” + +136, 138, 140 West Short Street + +LEXINGTON, KY. + +May 22, 1914. + +Hon. Theodore Roosevelt, Oyster Bay, N.Y. + +Dear Sir: + +In common with Progressives all over the United States, I am delighted at your return from the wilds. In fact, we are in the wilds here in the States and need a leader to show us the way out. + +Men of all political faiths are looking forward to an opportunity to vote for you again. The country is realizing that the peace fellows [are more] are mere flunkies to their fears and trying to lead the people into the beatific attitude of the ostrich which permits the hunter to slip up on it. + +It is charming to us "old line" Roosevelters to hear the Democrats "take water" on the question they so often made in the past, that + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/40_pg1_repeat1.md b/outputs/old_scans/40_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..465db134304718a227cb7dc1e4210eb72f5c6e89 --- /dev/null +++ b/outputs/old_scans/40_pg1_repeat1.md @@ -0,0 +1,18 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Louisville Jan 7th 1862. + +Hon. Joseph Holt. + +My Dear Sir. + +My much esteemed friend, Mr. H. G. Cleggett, is desirous of obtaining an appointment as Pay Master or as Commissary of Subsistance in the U. S. Army. + +Mr. Cleggett has long been a resident of Louisville, and I know him to be a man of strict integrity, and is also possessed of fair business capacity and of industrious habits. In a word he is altogether worthy of public and private confidence. + +If you can be of any service to him in attaining his object you will much oblige Yours truly + +Yours truly +T. F. Bullock + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/41_pg1_repeat1.md b/outputs/old_scans/41_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..38e80aebe666da32bb9ffdb4850cb14ed6d7d522 --- /dev/null +++ b/outputs/old_scans/41_pg1_repeat1.md @@ -0,0 +1,13 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Jany 8th, 62 + +Honble J. Holt + +Dr Sir + +I shall expect you to dine with me tomorrow. (9th) — at 3 1/2 oclock — + +Yrs truly J. B. Alexander 202 Olive + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/42_pg1_repeat1.md b/outputs/old_scans/42_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..80ccdfcd53f8b45ed10b80e4d81cf794125a798c --- /dev/null +++ b/outputs/old_scans/42_pg1_repeat1.md @@ -0,0 +1,15 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Boston Jan. 9. 1862 + +Honorable Joseph Holt &c &c &c + +Washington. D. C + +My dear Sir, My friend Andrew Low of Savannah, Ga. is as I think unjustly held as a prisoner at Fort Warren I am about to make an effort at the War Department for his release — + +I shall to day forward to Mr. Seward a copy of a letter which my friend has addressed to me & as he is a gentleman of high honor & integrity I am sure his + +Statements + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/43_pg1_repeat1.md b/outputs/old_scans/43_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..df1aa75c8a821b027dac9d63d4c14fc459a5183f --- /dev/null +++ b/outputs/old_scans/43_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +may be implicitly relied upon. Besides they are fully confirmed by my particular friends in Liverpool England where I met Mr. Lord during the last Summer. — During my two months in England I had my eyes open in behalf of our Government & had Mr. Lord been untrue to his position as endeavoring to keep himself in a "neutral position" it would certainly have come to my knowledge. — No good is to come to our cause by keeping such "lock & key" influential parties + +from the Confederate States who are innocent of any intended wrong towards our Govt. — And we must make large allowances for parties who were living in the Confederate States during May last & who have been abroad since & have not compromised themselves in acts against the United States. — I have known Mr. Lord for many years & formerly had large business transactions with him & always valued his word as I should his Bond. — I beg to recall myself to you as having had the pleasure of making your acquaintance while you were at the + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/44_pg1_repeat1.md b/outputs/old_scans/44_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fe6ce8c41cd520fa04d7bf940022d76c11dc29be --- /dev/null +++ b/outputs/old_scans/44_pg1_repeat1.md @@ -0,0 +1,13 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Hon Joseph Holt St Louis + +Dear Sir + +Enclosed please find our receipt for Eight Dollars and Ten Cents with Postage Stamps amt'g to One Dollar and Ninety Cents to balance your a/c — With thanks for your promptness — We are + +Yours truly Hegan & Scott H + +Louisville 10 Jany '62 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/45_pg1_repeat1.md b/outputs/old_scans/45_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9244db37c43b991b5ab9f1a39325f21212bd5977 --- /dev/null +++ b/outputs/old_scans/45_pg1_repeat1.md @@ -0,0 +1,17 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +St Louis Jan 10 th 1863 + +Hon Joseph Holt + +My Dear Sir — I am grateful that you did not speak less unkindly of me in Washington + +I have been admonished of my fault; it has ceased, and will not be repeated + +With high regard + +I am your Ob. St. + +T H Allen + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/46_pg1_repeat1.md b/outputs/old_scans/46_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c8a8d7008c0e24cdf24b8ebe6f6f47b2ffe33547 --- /dev/null +++ b/outputs/old_scans/46_pg1_repeat1.md @@ -0,0 +1,17 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Hon: J Holt + +St. Louis January 10. '62 + +Dear Sir + +My rent due 19 th Decr has not been paid, and as the amount \$1500, is a matter now of vital importance, I must trouble you, if not inconsistent with your public duties, to inform me whether Palmer Bean & Walker have any claims agst government, & if so when same may be paid. Mr Palmer informed me that he would pay out of the money, as soon as received. After my losses & sacrifices to secure a watch income for my family during war times, it will be exceedingly hard to lose this debt. My deep anxiety in regard to this, almost my last resource, will excuse this trouble. + +I opened my office as you will perceive from enclosed card. + +Very truly &c + +A Burnside + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/47_pg1_repeat1.md b/outputs/old_scans/47_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f91d0e600977553f6d16be28e603cba6cc59bfcc --- /dev/null +++ b/outputs/old_scans/47_pg1_repeat1.md @@ -0,0 +1,17 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +St Louis Jan 13th 1862 + +Dr Sir. + +A friend informs me that a few weeks since, he addressed a letter to me at Louisville, Ky. supposing me to be there. If received, it has probably been advertised. Please forward it to me here & + +oblige very respectfully your ob.t sevt J Holt + +Dr J. Speed Postmaster Louisville + +Learned yesterday you addressed & forwarded a number of letters to you at St. Louis. Resp'y + +William L. Kelly Assist PG Jany 15/62 Louisville KY + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/48_pg1_repeat1.md b/outputs/old_scans/48_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..af574009242903cbfe94f586d444a2a34c74184d --- /dev/null +++ b/outputs/old_scans/48_pg1_repeat1.md @@ -0,0 +1,11 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +this despatch, and will be deeply grateful to you, if you will kindly advise me what to do under the circumstances. It is my ardent desire to visit the U. States as soon as possible, and give my services to the Government for the suppression of the rebellion, and express to you personally the feelings which your kindness and interest in my welfare have inspired in my heart. + +On the receipt of the telegraphic news today that our difficulties with England were pacifically arranged I paid a visit to H. M. Ship "Pelican" in our harbor and had the happiness to see our glorious flag saluted by the nation, which a few weeks before was ready to declare itself our deadly enemy. Oh! how my heart will rejoice when we shall again be a united people, and attract the attention of the nations of the old world by our expanding greatness + +and glory, instead of painful criticism upon our national honor at home and abroad. I wrote to you last month at length, and have only time now to add the warmest expressions of esteem and affection from my father and mother. + +I am ever with devoted feelings of friendship Yours Most Sincerely J. Judson Barclay + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/49_pg1_repeat1.md b/outputs/old_scans/49_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..dc2efd7988b853a3eca66a4d60c68cb86a417ecb --- /dev/null +++ b/outputs/old_scans/49_pg1_repeat1.md @@ -0,0 +1,15 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Boston, Jany. 16th. '62 + +My dear Sir, + +After presenting to you my best respects, — I beg to say that I have mailed to your address a copy of a Letter to Hon. Peter Cooper, of New York — on the subject of the Union — + +I was advised to publish this Letter by some of our leading men here, — who saw the Manuscript, — so that it might be distributed to strengthen the Union sentiment. I shall be glad to know your views of its merit, — so that it may be made known & scattered if calculated to do good — I remain, with great respect + +Your sent & friend Halmun Capen + +Honble Jos. Holt, Washington, D.C. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/4_pg1_repeat1.md b/outputs/old_scans/4_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..75527d6410d037dc6b574da80bd5b3a8375b5b45 --- /dev/null +++ b/outputs/old_scans/4_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +THE BECKNER PRINTING COMPANY + +“WE NEVER DISAPPOINT” + +136, 138, 140 West Short Street + +LEXINGTON, KY. + +“Roosevelt got all his ideas from Bryan.” + +The tariff legislation is of course as honest as such things usually are, but it is theoretical, and is causing a vast amount of unrest and a corresponding slump in business. + +The banking legislation is apparently pleasing. + +An intense agitation is sweeping over the country on matters which are by some deemed religious and by others, political. The activities of the Knights of Columbus, and the improved public ideals about city government have centered men's attention on the Catholic church and its effort for Catholic schools. In this matter the administration is at outs with the Protestant sentiment of the country and doesn't seem to have sense or goodness enough to get right. + +If the president could open his mouth and "line 'em out like Teddy," or would stop his secret system of conducting + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/50_pg1_repeat1.md b/outputs/old_scans/50_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..7f13e1aff1922c5b5dabb0841ae8d9e837377736 --- /dev/null +++ b/outputs/old_scans/50_pg1_repeat1.md @@ -0,0 +1,17 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Keeping Sabbath - + +A pious man desires to comply with what he believes to be the will of God, but conscious of his own frailty, he recoils from enforcing others to conform to his own opinions. Such compulsion, despite what shape it may take, is the essence of persecution - God has given man no authority to compel obedience to his precepts. + +Religion is a thing between a man & his maker - & unless it be the voluntary offering of the heart, it is but a vain cold repetition of words, which cannot be acceptable to God - If a man does not believe that religion exacts it of him as a duty to abstain from labor on the Sabbath, he will submit with reluctance & in this submission there will be no piety on his part nor will it advance the piety of others - + +There can be no more justice or tolerance in this law than there would be in enforcing in favor of Catholics, upon the Protestants, an abstenance from [but] meat during lent, or in enforcing the [Mohometans] Christians to worship Mohamet - + +1st There is no one precept in the new Testament commanding us to keep a sabbath - If we are bound to keep one, it is in consequence of the Mosaic law - + +2. The language of the 4th commandment is, "The seventh day is the sabbath of the Lord" But the Christians keep the first day, not the seventh - + +3. There is not a single word either in the old or new Testament, nor even an allusion relating to the substitution of the first day for the seventh - The subject is not mentioned in any of the discourses of Christ nor in any of the epistles of his apostles - + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/51_pg1_repeat1.md b/outputs/old_scans/51_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fef5cd02fe47689cc3a988cdf2a8a595c0d81343 --- /dev/null +++ b/outputs/old_scans/51_pg1_repeat1.md @@ -0,0 +1,11 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +on the whole it is certain if Christians are bound to keep a sabbath, it is in consequence of the fourth commandment & in the seventh day & not the first - Saturday & not Sunday - our law then setting apart the 1 st instead of the 7 th has added to the Christian law & imposed a restraint upon Christian liberty - + +The primitive Christians did not observe any sabbath - Till the reign of Constantine A D 300 to meet together on the first day of the week for religious worship in the morning or evening & to pursue their usual avocations during the rest of the week - The work of Justin Martyr a very distinguished Christian Advocate who wrote about the year 150 throws much light on this subject - It is a dialogue between a learned Jew & a Christian - The Jew upbraids the Christian because his sect observe no sabbath but are in this respect like the Pagans - Justin makes the Christian admit & justify it & he proves at the Jewish sabbath as a day of mere idleness - & states that as "sabbath & sacrifices & oblations began from Moses so according to the counsel of your fathers they were to end in Christ" again continuing his argument against the observance of a sabbath he says; "Do you not see that the elements are never sick nor keep a sabbath?" Justin thus admits that the Christians did not keep a sabbath & insists that they were no more bound to [to] do it than to conform to + +any other Jewish rite which had been abrogated by the Christian dispensation - The first day of the week was not observed as a sabbath until A D 300 under Constantine when Christianity had become the religion of the state. an edict then went forth commanding + +"all the Judges & town people & the occupation of all trades to rest on that venerable day of the sun (die solis) But let those who are situated in the country freely & at full liberty attend to the business of agriculture because it often happens that no other day is so fit for sowing corn & planting vines &c" - The autocrat did not deem it prudent to include the yeomanry in his despotic edict & it was not till long afterwards that the Priesthood having gained great power in the state were enabled to arrest the business of agriculture - on the whole it is no part of the Christian duty to keep a sabbath & if any day is to be thus hallowed it is the 7 not the 1 st . It is an innocent usage - let those who wish it continue to observe it, but do not compel others to do it - It has sprung from a foul unnatural union between church & state & has its origin in [all] the same source with all the other papal corruptions of Christianity which have overwhelmed & buried the simplicity of our religion under a flood of idolatrous ceremonies + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/52_pg1_repeat1.md b/outputs/old_scans/52_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0b91106b9e52d77b1b5f4e4f32780fe827068a3e --- /dev/null +++ b/outputs/old_scans/52_pg1_repeat1.md @@ -0,0 +1,5 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Crusades I must write a composition on the crusades showing the design with which they were undertaken, the zeal with which all the Christian princes engaged in them & the good effect it produced in Europe by bringing the military art to perfection, polishing the manners of the people & destroying a great measure the feudal system. This last war one of the greatest blessings it conferred upon the civilized world. — the historical part of these crusades may be found in an abridged form in Lytton's History + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/53_pg1_repeat1.md b/outputs/old_scans/53_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..e9f7b5f640646fa4612a745b9e429ba404075b9d --- /dev/null +++ b/outputs/old_scans/53_pg1_repeat1.md @@ -0,0 +1,5 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Crusades March 27th 1825 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/54_pg1_repeat1.md b/outputs/old_scans/54_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..9890580247cb1769641ba8d0d55cb9ed845007aa --- /dev/null +++ b/outputs/old_scans/54_pg1_repeat1.md @@ -0,0 +1,5 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +'Twas such a night as this: There was not a breath of air to ruffle the smooth surface of the calm Adriatic: naught was heard save the distant tinkling of the solitary sheep bell, & the low barking of the honest watchdog. He stood beside a tomb — a deep sigh rent his bosom & even & anon as he cast his tearful, languid eye to the pale, chaste moon, [low] of heaven, he exclaimed: oh Jack! what a night — for catching coons! + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/55_pg1_repeat1.md b/outputs/old_scans/55_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..2344b14048f480ab50c3707720f1208dfc85bbbf --- /dev/null +++ b/outputs/old_scans/55_pg1_repeat1.md @@ -0,0 +1,33 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +94. what is method? + +A. the disposal & arrangement of our thoughts in such a manner that their connexion & dependence may be clearly seen — + +95. how is method divided? + +A. into the analytic & synthetic. + +96. what is the analytic method? + +A. it is the having things back to their source & resolving knowledge into its first & original principle. + +97. what is the synthetic method? + +A. the deducing of truths from first principles and connecting them according to their [depend] mutual dependence. + +98. what are these methods otherwise called? + +A. the methods of resolution & composition or the methods of invention & science. — + +99. what are the preparatory qualities to invention & attention, a comprehensive understanding, & a judicious choice of intermediate ideas — + +100. to what branch of knowledge does science belong? + +A. to that only which is derived from the contemplation of our ideas. + +101. is our knowledge of the real existence of bodies intuitive. + +A. no. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/56_pg1_repeat1.md b/outputs/old_scans/56_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..62a0bd1b504f9ccb1b5e118034fb3edcec292b56 --- /dev/null +++ b/outputs/old_scans/56_pg1_repeat1.md @@ -0,0 +1,49 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Divisions of Logick. + +1. what is Logick? + +A. the art of reasoning & communicating knowledge the operations of the human mind in acquiring or that science which explains + +2. into how many parts is it divided? + +A. into four. + +3. of what do they treat? + +A. the first treats of Simple apprehension & of judgement. 3d. of reasoning & 4th of method. + +4. what is Simple apprehension? + +A. it is the attention of the mind to the impressions made upon it by surrounding objects. + +5. what is consciousness? + +A. it is the attention of the mind to its own operations. + +6. what are the sources from which all our [knowledge] original ideas are derived? + +A. Sensation & reflection. + +7. what ideas do we get from sensation? + +A. our ideas of heat, cold, colour &c. + +8. what ideas do we get from reflection? + +A. our ideas of thinking, willing, believing &c. + +9. how are our ideas divided? + +A. into Simple & complex. + +10. what is a simple idea? + +A. it is an original impression existing [under] in the mind under one uniform appearance, without variety or composition. + +11. give an instance of a simple idea of sensation & also of reflection. + +A. [cat] the idea we have of colour is a simple idea of sensation & the idea we have of willing is a simple idea of reflection. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/57_pg1_repeat1.md b/outputs/old_scans/57_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..36e356faa3681aa9a8ad85d7b6fc23375afc72ac --- /dev/null +++ b/outputs/old_scans/57_pg1_repeat1.md @@ -0,0 +1,7 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +12. in what way do simple ideas find admission into A. By the proper inlet of nature into the mind. 13. what is a complex idea? A. It is an idea of a complex object as it is an idea formed by the combination of simple ideas. 14. how are complex ideas divided? A. into those of real existence & those formed by the mind. 15. give an instance of a complex idea of real existence & also of one formed by the mind. A. the idea we have of any substance is a complex idea of real existence & the idea we have of hours miles feet or ye &c is a complex idea formed by the mind. 16. what is a substance. A. it is something that subsists of itself & is the subject of modes or qualities. 17. how are modes or qualities divided? A. into essential & accidental. 18. what is an essential mode? A. it is some quality belonging to a body see absolutely [to] necessary to constitute it what it is roundness is an essential mode of a Ball. 19. what is an accidental mode? A. it is some quality of a body which does not necessarily belong to it. red blue &c would be an accidental mode of a ball. 20. what is meant by the essence of substances? A. nothing more than their internal structure & constitution 21. what is the foundation of the different species of corporeal substances? + +45. what is meant by the predicate? A. the attribute or quality affirmed of the subject. 46. what is the copula? A. the word or term serving to connect the subject & predicate. 47. what is the first division of propositions? A. into affirmative & negative. 48. what is meant by an affirmative & what by a negative proposition? A. an affirmative proposition is that in which the subject & predicate are connected, a negative that in which they are disjoined. 49. when does the negative particle disjoin the subject & predicate? A. whenever it affects the copula. 50. what is the next division of propositions? A. into universal & particular. 51. what is meant by a universal proposition? A. it is a proposition whose subject is some general term & the predicate which is affirmed of it, can without restriction be affirmed of every individual contained under it. 52. what is meant by a particular proposition? A. a proposition whose subject is some general term but attended with a mark of limitation showing that the predicate affirmed is restricted to a part only of the individuals contained under the universal term. 53. what is the celebrated fourfold division of propositions? A. into universal affirmative, universal negative, particular affirmative & particular negative. 54. what is the 3d division of propositions? A. into absolute & conditional. 55. what is an absolute proposition? A. that wherein we affirm some property inseparable from the idea of the subject. as God is omnipotent. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/58_pg1_repeat1.md b/outputs/old_scans/58_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..3f169f5d8408d9ea645f0a207a0fc6197f9128dd --- /dev/null +++ b/outputs/old_scans/58_pg1_repeat1.md @@ -0,0 +1,36 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Alfred T. Osmond (Pupil) Bordentown. + +Ansd. Feb. 1, 1902. (In Clara Barton's handwriting.) + +Alfred T. Osmond, +Stamps, Stencils, Inks, Brushes, +Awnings & Window Shades, +213 N. Broad St., Trenton, N.J. + +Trenton, N.J., Jan. 17, 1902. + +Miss Clara Barton + +For years I have desired to write you and if possible receive a letter from you. Indeed I was about to [to] for at the breaking out of the Spanish War. I deferred, but now feel the desire pressing upon me. About the year 1854 I attended your school at the intersection of Crosswicks and Burlington Sts., Bordentown, and at the finishing of the larger school attended that, but not in your department, being placed under your direction in the principals room on the lower floor. Time has rolled rapidly away, almost half a century since then, still many of us are left, no doubt, but scattered, we know not where. I myself, ere the end of this month, the 30th, will be three score years of age. I am strong and well, always been very active, am a strong temperance advocate, a member of the Christian Church and living for the next life. I have had a dear little family, wife, son, daughter. Death claimed my wife in April 1886, my daughter in March 1901 leaving me a grandson, whom my son has taken. I have always tried to not lose sight of those past days, and have with pride pointed to the fact that I was one of your scholars. May God continue to protect and bless you. + +You have been a noble woman, how I would love to meet you and take your hand. + +Should you receive this please answer if with only a line. + +Respectfully yours, + +Alfred T. Osmond, + +Formerly of Bordentown, N.J. + +In reciting the story of how Clara Barton happened to be the founder of the first successful public school in New Jersey, at Bordentown, I have drawn from diaries, letters and other memoranda, which I have found in my work of examining the vast accumulation of her literary relics, for the purpose of procuring material for the final biography of Clara Barton. I have so arranged the matter that it may appear largely as though written by herself, in fact, the most of my paper is in the form of quotations from her writings. + +While Miss Barton was a student at Clinton Institute, Oneida County, N.Y., she became acquainted with Miss Mary Norton. "She had been much with me," Miss Barton writes, "and almost unconsciously to myself, my teacher instincts had doubtless made her school life easy. Her letters home had called from the parents a most urgent request for me to promise them a visit in the future. This was of so genuine, hearty and at the same time delicate a nature that I could not find it in my heart to utterly decline. This was the home of the Veteran Quaker, Richard Norton, of Hightstown, N.J. + +Early in the autumn of 1851 Miss Barton made the promised visit. + +"As the October leaves commenced to fall," she continues,"I ventured some remarks concerning home, but these were met by a protest so general and vigorous as to unbalance my decision and lead me to consider. "My suggestion that I ought not pass so much time in mere idleness, and that there was nothing there to occupy me, drew from Uncle Richard the rejoinder, "If thee could teach our winter school, Miss Clara, thee could find plenty to do. But thee could not keep a school could thee?" I thought "perhaps I might." "I know thee could teach them Miss Clara, but these farmer boys that go to our school in the winter are men grown, and sometimes rough. Thee would not dare to undertake them?" "I thought I 'might be able to manage them', and it was decided that I attempt the winter school, consisting of about forty pupils, a venture never before essayed by a woman; "Graded School?" Ah no! not even a free school. Public schools were merely a + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/59_pg1_repeat1.md b/outputs/old_scans/59_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c692378d3ab62e8714877a8f4964892c1a5a3525 --- /dev/null +++ b/outputs/old_scans/59_pg1_repeat1.md @@ -0,0 +1,27 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +thought in the State of New Jersey at that date; and not a popular thought at that. + +All expense inuring from the public treasury to individuals was held as pauperism. Thus, the public payment of a teacher for the children of a family placed them in the same category as having food or clothes provided at public expense. The people of no self-respecting community would submit to that degradation. Public schools in that day ceased with the southern boundaries of New England and New York. Each scholar was assessed a certain amount, the aggregate of which formed the teacher's salary, something on the principle of select schools of today. This was a "new thought" to me, and fell with overwhelming force. + +I lived over again the days of little district schools in Massachusetts. Those, at the time, I had regarded as sorely lamentable; but this system for the children of very poor, unfortunate, or unworthy parents seemed too unbearable. + +I think it was the first Monday in December 1851, when I classed my school and commenced teaching it. To me, there was a tender pathos in the faithful efforts of my bashful farmer boys and girls, and a mingled sympathy when the lengthened days of springtime called them to their accustomed duties. + +The winter's observation and thought had gone far towards maturing my plans. This individual system of schools seemed childish. + +I had playfully asserted from the first, that the financial method of their system was beyond my mathematics. I had, before now, kept time for working men, but never for children, and could not learn now. + +Trenton, Burlington and Newark, as cities, had made efforts at public schools, with more or less success; usually the latter, but all large towns or boroughs remained unchanged. .... + +I talked matters over with "Uncle Richard" and it was arranged that I visit Bordentown. ... ... ... ... ... + +Learning of a school committee, my first business was a personal call upon its chairman, Mr. Peter Suydam. From him I gained confirmation of the fact, that as a State, New Jersey had made legislative provision for the introduction of public schools, but that, owing to the strong opposition of public sentiment it had not proceeded to make the law obligatory. That the schools were generally, if not entirely, taught by ladies, more frequently in their own homes, as a means of eking out a slender living; widows and people who "had seen better days"; often elegant persons, but with no fitness for the position, and no ability for instruction beyond their own limited knowledge gained years before in some similar manner; when this limit was reached, and the pupil became aware of it, he became an "undesirable citizen" and was graduated into the street. The town was full of these children, and out of some seven hundred within a narrow limit of school age, only about three hundred and fifty were in school at all. The remaining hundreds bore all grades of reputation, from mere "absentees" to "renegades." + +A year or two before, an effort had been made in the direction of a public school. A delapidated house, some little distance from the center of business had been fitted up, and a man engaged to teach a public school in it, but the effort failed, and the house was closed in disgrace and discouragement. + +All of this information left me in what might properly be termed "a state of mind." + +Not that I was more discerning or more susceptible, or had any keener sense of justice or of humanity than those about me, but it was something so entirely new to me, and occurring rather in my own lines, that it made its impression. That was probably the only real difference between us. A case of environment. If I had been reared among them, I should have felt the same. "There is nothing like getting used to a thing" they tell us. One might add here, that nothing exceeds that, + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/5_pg1_repeat1.md b/outputs/old_scans/5_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..f399bb47a244d4acd14ae3fb75c797d1bf9658f5 --- /dev/null +++ b/outputs/old_scans/5_pg1_repeat1.md @@ -0,0 +1,17 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +THE BECKNER PRINTING COMPANY + +“WE NEVER DISAPPOINT” + +136, 138, 140 West Short Street + +LEXINGTON, KY. + +public affairs, he would stand much better. You have educated us to expect the president to talk, and he who falls short of your measure, will be a public disappointment. + +Then the president ought to say a wise word to allay the Protestant ill-feeling and at the same time let Rome know her place in such a way as would prevent exception being taken, and he would immensely please again. He is a Protestant, and can not be expected to attend Catholic ceremonies and lend himself to even the appearance of intrigue. + +All together the public wants you, and is looking to you to say something to check the orgy of "peace" going on in Washington. Think of \$25,000,000 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/60_pg1_repeat1.md b/outputs/old_scans/60_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6a11692d2ec76f268375431ff37fabc6ac249d73 --- /dev/null +++ b/outputs/old_scans/60_pg1_repeat1.md @@ -0,0 +1,25 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +sustain it. + +Mr. Suydam laid my proposition Before the school Board and the following afternoon, to my surprise, I was most courteously invited to sit with them in their deliberations. The subject was fairly discussed, but with great misgivings regarding the hazardous nature of the experiment and its probable result. However they came to the unanimous decision that the old school house be refitted, and a school commenced. + +The tardy preparations dragged into the second month, but finally about the fifth week, notice was given in the "Bordentown Register" and printed notices a foot square posted on all customary places, on spare boards, street corners, fences, market places, and tree trunks, that a public school, taught by Miss Clara Barton, in the brick school house corner of Crosswick Street would commence on Monday next at 9 o'clock A.M., a good attendance was hoped for by the school committee. Signed,-- etc. + +The early springtime waned in my waiting and it was nearing June when a prospective teacher with a decidedly New England aspect, a few books and desk outfit walked thoughtfully up the partially country street, turning abruptly to the right, as a solidly built brick house of small dimensions was reached, all firmly closed. A line of post and rail, "Virginia fence" commencing at the opposite corners of the house ran along, separating the yard from the opposite pasture land. On the top, or fifth rail of the fence were perched six boys ranging from ten to fourteen years, with the exception of one little brother of six; some shod, some barefoot, swinging their feet in concert. + +We sauntered about the yard, picked flowers, found a young four-leaf clover for good luck, discovered a tiny yellow bird's nest on a limb nearby, and decided to protect it faithfully, allowing no one to disturb it, and finally, as if just remembering that I had a key to the + +house, unlocked the door, and went in. + +I recall at this day the combination of odours that greeted the olfactories. The old musty smell of a long shut, untidy house, the pungent flavor of freshly cut southern pitch pine, and the bitter soot of the long iron stove pipe rusting for years. + +Altogether, it would have done credit to old, far-famed Cologne, said to be the worst smelling city in Europe. Save the half dozen little books I had, there was not a book in the house. They had brought none with them, from the doubtful impression at home, even if they would find any school, or stay if they did. But this was a matter of small importance, the lack of books being more than supplied by the two lusty black boards on opposite sides of the walls, and three school maps, of the world, the United States and Europe, which I had expressly named to the "Committee" as required among the furnishings. + +School was not thought of, but house keeping was the order of the day. By twelve o'clock we were spick and span, clean and all ready to go home for dinner. + +The stroke of one found us all at our posts. + +Almost imperceptibly we became very greatly interested in the maps, and little "Alex" was delighted with the "big slates", as the black boards were to him. They had never seen a blackboard in school. In that three hours until four o'clock we had travelled the world over, sailed with Columbus to discover America, grown indignant at his treatment. We had found how it came to be hot in some parts of the world and cold in others, and as we wiped our sweaty faces, "wished it wasn't quite so hot here." We went to Africa for lions, leopards, elephants and great snakes; to Italy for oranges and grapes; to California for gold, and "wished we had some of it here, we would have a better school house." We were travellers, and really knew more about the world and its ways than we had ever known before in our lives. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/61_pg1_repeat1.md b/outputs/old_scans/61_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..aa6d76b9f7eaea9a9252bb4ff54f394de86fb2ba --- /dev/null +++ b/outputs/old_scans/61_pg1_repeat1.md @@ -0,0 +1,15 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +six hours through five successive days. There was no respite. The succeeding week commenced the actual term. We had asked the appointment of one man among the many teachers, on to whose shoulders could be shifted the heaviest burdens, if desired. + +I commenced on Monday with a hoarse, tired voice, something I had never known. In spite of all palliatives, utterance grew weaker and more difficult, and finally ceased. The other teachers, and my own splendid pupils came tenderly to my aid relieving me of every duty possible to be done. To assure the proper arrangements and management of the school in its beginning, I hopefully remained for some weeks at my voiceless post, but it was a vain effort. I began to realize that the weakening was not entirely confined to the voice. The labors of the past months had not been a pastime for either myself or my invaluable helpmeet, and in the midst of protests, loyal and loving, our resignations were given. We could scarcely say they were accepted. + +I have selected one letter from among my Grand Aunts papers to show with what affection and joy she looked back on the old school days in Bordentown. + +I have searched through the earliest diaries we have and find this little entry on the fly leaf;- Oct. 13/51 Left home for Htn. (Hightstown) Oct. 23 Thursday. Commenced school. Attended a weekly at Mrs. Tailors in the evening. + +And in the back of the same little diary I find May 27/52. Arrived in Bordentown. + +Immediately following this [little] entry is a list of "Poets from Chaucer to the present day," which fill up some ten or twelve pages of the little book. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/62_pg1_repeat1.md b/outputs/old_scans/62_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..64fe059d316d1d9e9180bb4a9ec3968a9b03d1a4 --- /dev/null +++ b/outputs/old_scans/62_pg1_repeat1.md @@ -0,0 +1,48 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Glen Echo, Md., +February 1, 1902. + +Mr. Alfred T. Osmond, + +Trenton, N.J. + +Dear Mr. Osmond;- + +It would surely carry you back many years if I were to say "My dear pupil", still it would be true, and I want to return you my thanks at once for remembering that you were my pupil, and the dear old days of the school, that really meant so much, for they have lived until today, and never in any way has it passed out of the minds, I think, of any pupil I was permitted to have. Their life-long loyal allegiance to me is beyond my comprehension. Little, as many of them were, trifling as the days must have seemed, it is a most remarkable thing that all have remembered those few months and cherished them with a loyalty that the most ambitious teacher could but prize. Scarcely a month passes that someone does not reveal him or herself to me, scattered over the whole country, until there are times when I feel that I should like to gather them all together once more and sit among them and the memory of the old child days. + +I am glad that you told me of your home and surroundings, glad that they are so peaceful and that the sunset of life, coming to us all, brings as sory lights as it does, and let us pray that, in its soft reflections, we may one day go out to that better land where the hues are always bright and, we trust, the paths easy. + +I shall be glad to hear from you at any time. Thanking you for your kind remembrance, I remain, dear Mr. Osmond, + +Faithfully yours, + +Clara Barton." + +STATE OF NEW JERSEY +DEPARTMENT OF PUBLIC INSTRUCTION +TRENTON + +CALVIN N. KENDALL +COMMISSIONER OF EDUCATION + +April 15, 1920 + +Mr Stephen E. Barton +60 Congress Street +Boston, Mass. + +My dear Sir: + +I was very much interested in your letter of April 11. Contributions to the Clara Barton Fund should be sent to me. I will send you a receipt. + +Will you please tell whether or not you are a relative of Miss Barton? + +I am, + +Very truly yours + +C. M. Kendall +Commissioner of Education + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/63_pg1_repeat1.md b/outputs/old_scans/63_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c8e8766c6f824687232c5d3985580d4f4cb21d47 --- /dev/null +++ b/outputs/old_scans/63_pg1_repeat1.md @@ -0,0 +1,35 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +State of New Jersey +Department of Public Instruction +Trenton + +Education Bulletin + +Contents + +PAGE +Clara Barton—Teacher in New Jersey 67 +Visit-the-Schools Week 69 +Campaign for Betterment of Schools 71 +The Task, the Teacher and the Pay 73 +War Work of Hamilton School at Harrison 74 +A Problem at Ventnor City 75 +The New Continuation School Law 76 +How a County Superintendent Secured Consolidation of Schools 78 +Extract from Helping Teacher Report 79 +Elizabeth A. Allen Memorial Fund 79 +School Lunches at Leonardo 80 +Physical Training Creed 80 + +Vol. VI + +January 1920 + +No. 5 + +Published monthly except July and August + +Entered as second class matter January 8, 1915, at the postoffice at Trenton, New Jersey, under the Act of August 24, 1912 + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/64_pg1_repeat1.md b/outputs/old_scans/64_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..6728cea07323363dc0825a9f7b4087690d34a663 --- /dev/null +++ b/outputs/old_scans/64_pg1_repeat1.md @@ -0,0 +1,48 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +It seems to the Commissioner that the school children and school teachers in New Jersey may wish to make a very small contribution—in the case of the children not to exceed a penny each, and in the case of the teachers not more than five cents each—to pay for the building, for its removal and the minor repairs that it needs, and possibly to establish a fund the interest of which could be used for its upkeep and to pay a small sum to a person to show the building to visitors. An amount not to exceed \$1500 or \$2000 would probably answer all purposes. + +It is the plan of the Commissioner a little later to ask for this donation from such schools as would like to take up the matter. + +If there should be an amount in excess of what is needed it could be turned over to the Red Cross. + +Of course this whole matter of purchasing the old Clara Barton school is a sentimental one, but the Commissioner could not bring himself to feel that it would be the wish of the school fraternity of New Jersey to see the building destroyed. It was necessary to move in the matter at once, and the Commissioner, acting as he believed in the interests of and in accordance with the wishes of the teachers of the state, has taken this step. + +In a recently published biography of Clara Barton, by Percy H. Epler, occurs the following pertaining to her life as a teacher in the schools of New Jersey. + +Miss Norton recognized her friend's genius for teaching and in 1853 prevailed upon her to accept a post in the New Jersey village of Hightstown. + +Some ten miles or so away was Bordentown. Rumors of the extraordinary ability of the little woman to conquer schools where strong men had been driven out by unruly pupils radiated wherever Clara Barton went. From Hightstown news of her power came to Bordentown. + +Prejudices existed there against public schools. Some were too denominational in religion to be broad enough to desire them; others too proud to send their children to the public school, which had often been styled "free schools for paupers." + +Whenever the public school system had been tried among a people divided by sectarian quarrels, the citizens themselves split over the question, while the children, catching their lack of respect for a school system, broke up the sessions and ran wild on the streets. + +Miss Barton saw the need in Bordentown and she went to meet it. + +"A public school is impossible," she was told. "It has failed every time." + +"Give me three months and I will teach free," was her challenge. + +Never was there a campaign against odds but Clara Barton answered it with this argument of action. She did not demand that something should be done; she demonstrated that it could be. + +She took a tumble-down unoccupied building with six pupils. In five weeks the building was too small. Each of the six pupils had become a living advertisement. Emerson has said that it is not the school that educates—it is the schoolmate. Clara Barton recognized this truth and sought to reach out through these first pupils. She studied each child individually. . . . In this was the magic of her success. + +Something of the way in which she was regarded is shown by the following letter from a member of this first class—George Ferguson, now of Brazil, Indiana. "My memories of Miss Barton are certainly the most pleasant. She was kind to her students, pleasant in her work, gentle in disposition and took an interest in us all. We loved her almost as much as we loved our mothers, and it was not without pangs of regret that we saw her give up her pupils and school work on account of failing health. . . . I don't think she ever had a pupil but that loved her. Bad boys interested her as much as the good ones. The first letter I ever wrote in my life I wrote to Miss Barton. When she went away on her vacation she asked her students to write to her. We all did, and she answered all with personal letters. I can remember myself writing that letter as if it were only yesterday, and I was mighty proud of the answer I received. Since then I have been corresponding with her and have letters from her which I prize highly." . . . + +“Remembering that fully one-fifth of my life has been passed as a teacher of schools,” she remarked twenty years after, “it is not strange that I should feel some interest in the cause of education, some sympathy with those who labor in it as its teachers, some affiliation with the parents and people who bear its expenses, and secure its benefits, and some interest in the children and youth who receive them.” + +What community in New Jersey will be the first to honor itself and to honor Miss Barton by attaching her name to a public school building? + +VISIT-THE-SCHOOLS WEEK + +To Local Boards of Education, Superintendents +of Schools, Principals and Teachers: + +During each of the past three years a week has been designated as Visit-the-Schools Week. Last year more than thirty thousand persons visited the schools during the week set apart for this purpose. + +The week which is designated as Visit-the-Schools Week this year is the one beginning Monday, February 16. It is hoped that a larger number of persons will visit the schools this year than visited them last year. + +This week comes at a time of the year when fathers are not so busy as they are at some other seasons, and they, as well as the mothers, can visit the schools. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/65_pg1_repeat1.md b/outputs/old_scans/65_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..fddfede0921f4d23a4da174ca874208498d37f81 --- /dev/null +++ b/outputs/old_scans/65_pg1_repeat1.md @@ -0,0 +1,64 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +almost \$200 more than the median wage of high school teachers throughout the country. From figures obtained from cities in the central section of the United States it was found that it was worth per year \$394 more to carry bricks than to train children; \$363 more to mould dough for bread than to mould boys and girls into citizens; \$890 more to hammer hot iron than to hammer ideals, and \$1024 more to build frameworks for buildings than frameworks for character. + +There seems no solution of this problem save the intelligent study of the work done by teachers and the establishment of schedules of pay proportional to the preparation demanded and the necessary expenses incurred. When this is done and salary schedules put upon this basis no teacher in the country will be expected to start teaching at less than \$1000, and the schedules will be so arranged that additional preparation, conscientious work and special ability will receive their reward in teaching in the same sense and as surely as these same elements would be rewarded in any other line of work. + +The state of New Jersey ranks toward the top of the states in the matter of salaries paid to teachers. Because of this all branches of the educational system are greatly interested in an adequate adjustment of teachers' wages. With such an interest and a maximum of cooperation on the part of all groups involved there is no reason why New Jersey should not be the first state to put its teachers' salaries upon a satisfactory and scientific basis—that of paying all teachers a living and a saving wage in such a way that the maximum of service may be given to the schools. + +WAR WORK OF HAMILTON SCHOOL AT HARRISON + +Hamilton School Number Two, in Harrison, Hudson County, made a record in its war activities. This is a school of eleven classrooms. The record follows: + +6 Large hospital pillows +12 Large cases +149 Colored ambulance pillows +148 Small white pillows +136 Small white cases +549 Washcloths +62 Hospital wipes +4 Eye bandages +2 Chin bandages +384 Handkerchiefs +96 Comfort kits +200 Sweaters +35 Mufflers +311 Pairs of socks +31 Helmets + +189 Pairs of wristlets +14 Pounds of lint +560 Pounds of tinfoil +36 Baby shirts +6 Romper sets for Belgian babies +3 Auto trucks of clothing +250 Cards of darning cotton wound by children +18 Medicine glass covers +Liberty Bonds ..... \$3000.00 +Thrift Stamps (1918) ..... 1865.00 +Thrift Stamps (1919) ..... 951.75 +Junior Red Cross ..... 113.00 +Red Cross Drive ..... 301.83 +Victory Drive ..... 300.00 +Salvation Army Drive ..... 612.49 +State Memorial (Soldiers and Sailors) ..... 220.00 + +A PROBLEM AT VENTNOR CITY + +Ventnor City, Atlantic County, has one of the best school systems in the state. Its people are public spirited and are willing to spend money on their schools, and its superintendent, Mr. Halliday R. Jackson, is a leader of teachers. Mr. Jackson recently issued a statement entitled "Our School Problem," which is worthy of reproduction in the Bulletin. + +What other town in the state has a broader or more comprehensive program than Ventnor City? + +The statement follows. + +There are cities where the classes average thirty-five pupils, but are they the places to which people move because of the schools? + +Is Ventnor City, which has built up a splendid reputation for its public schools because of its small classes and excellent teaching to drift into the conventional type of public school system? + +Is it going to lead a humdrum conventional school life—quiet, un-offending and negatively happy—doing as many others do, doing it about as well as they do it and satisfied to do just that? + +Or is Ventnor City going to keep the place it has won and still further extend its school facilities? Schools either move ahead or slide back. They cannot stand still and still hope to lead a moving procession. + +To be an advertising feature the schools must be better than the average and so much better that the ordinary man can see it. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/67_pg1_repeat1.md b/outputs/old_scans/67_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..1a1bc90f60cc04527fbdccc30b4cf9179e040278 --- /dev/null +++ b/outputs/old_scans/67_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +
Ages known: Ages unknown:
Whites ..... 428
Blacks ..... 1,546
Total..... 1,974
Grand total ..... 4,981
+ +NATIVITIES. + +
United States..... 2,263 Sweden..... 5
England..... 71 Bavaria..... 2
Ireland..... 216 Canada..... 59
Scotland..... 20 Hanover..... 1
Wales..... 7 New Brunswick..... 7
New Wales..... 1 Mexico..... 1
France..... 22 British Provinces..... 1
Spain..... 2 British America..... 1
Germany..... 229 Baden..... 1
Russia..... 1 Nova Scotia..... 4
Prussia..... 9 West Indies..... 1
Norway..... 14 Italy..... 1
Switzerland..... 14 Hungary..... 1
Denmark..... 8 Cuba..... 1
Portugal..... 1 At sea..... 1
Holland..... 4 Contrabands..... 1,546
Saxony..... 1 Unknown (whites)..... 476
Europe..... 2 Total..... 4,981
+ +STATE OF ENLISTMENT OR DESCRIPTION OF SERVICE. + +
Maine..... 164 Ohio..... 191
New Hampshire..... 76 Iowa..... 14
Vermont..... 57 Indiana..... 55
Massachusetts..... 177 Illinois..... 20
Rhode Island..... 13 Wisconsin..... 86
Connecticut..... 38 Michigan..... 166
New York..... 944 United States..... 91
New Jersey..... 87 Quartermaster's department..... 99
Pennsylvania..... 618 Commissary department..... 5
Delaware..... 26 Ordnance department..... 1
Maryland..... 58 Hancock's corps..... 15
District of Columbia..... 5 Veteran Reserve corps..... 127
Virginia..... 74 Signal corps..... 2
North Carolina..... 48 Marine corps..... 1
South Carolina..... 14 Provisional cavalry..... 4
Georgia..... 29 Andrew's S. S..... 1
Florida..... 1 Hospital attendant..... 1
Alabama..... 16 Brigadier general..... 1
Mississippi..... 4 Citizens..... 2
Kentucky..... 6 Military R. R..... 1
Tennessee..... 8 Contrabands..... 1,546
Missouri..... 4 Unknown (whites)..... 58
Minnesota..... 25 Total..... 4,981
+ +CAUSES OF DEATH. + +
Aneurism..... 1 Abscess..... 8
Accidental..... 19 Anaemia..... 3
Acute consumption..... 1 Bronchitis, chronic, &c..... 30
Apoplexy..... 19 Bayonet wounds..... 2
Apoplexia serosa..... 1 Bilious colic..... 3
Anasarca..... 4 Bright's disease, (kidneys)..... 3
Amputation..... 113 Cardiac disease..... 2
Ascites..... 6 Cerebritis..... 2
Asphyxia..... 3 Cerebral spinal meningitis..... 15
Astheria..... 10 Cerebral congestion..... 2
Assnoce..... 3 Chronic diarrhoea..... 437
+ +CAUSES OF DEATH—Continued. + +
Chronic pleurisy..... 1 Fever, typhus..... 5
Chronic dysentery..... 18 Fever, scarlet..... 1
Chronic disease of heart..... 1 Fever, spotted..... 3
Chronic rheumatism..... 2 Gangrene..... 32
Congestion of lungs..... 7 Gastritis, acute, &c..... 7
Congestion of brain..... 6 Gastro enteritis..... 1
Congestive chills..... 4 Hemorrhage, &c..... 16
Concussion of brain..... 1 Hemorrhage of bowels..... 2
Contusio..... 3 Hanging..... 1
Compound fracture of leg..... 5 Hemiplegia..... 2
Compound fracture of arm..... 1 Hepatitis..... 3
Compound fracture of femur..... 3 Hepatitis, acute, &c..... 1
Coup de soliel..... 4 Hepatic disease..... 2
Colligative diarrhoea..... 1 Hydrothorax..... 2
Convulsions..... 1 Hemoptysis..... 6
Consumption..... 9 Hernia..... 1
Colic..... 2 Injuries..... 9
Cynanche..... 1 Ictus solus..... 1
Compression of brain..... 2 Inflammation of brain..... 14
Cholera..... 1 Inflammation of lungs..... 18
Cholera morbus..... 5 Inflammation of bowels..... 9
Chorea..... 1 Inflammation of windpipe..... 1
Drowned..... 14 Inflammation of liver..... 2
Dextral hydrocele..... 1 Icerus..... 2
Diarrhoea, acute, &c..... 100 Icterus..... 1
Debility, general, &c..... 25 Intersusceptis..... 2
Diptheria..... 13 Idropathic abscess of thigh..... 1
Dysentery, acute, &c..... 63 Inebriation..... 2
Diarrhoea, hemorrhoid..... 1 Jaundice..... 7
Dropsy..... 3 Killed in battle..... 2
Dropsy of heart..... 13 Kicked by mule..... 1
Dyspepsia..... 3 Laryngitis..... 3
Delirium tremens..... 6 Laryngitis cynanche..... 1
Epilepsy..... 2 Lightning..... 3
Enterites gastro, &c..... 8 Lumbar abscess..... 1
Exhaustion..... 195 Murdered..... 6
Erysipelas..... 38 Measles..... 9
Endocardites..... 4 Marasmus..... 1
Empyæmia..... 1 Meningitis..... 6
Exposure and drink..... 2 Mucus dysentery..... 1
Exposure and diarrhoea..... 1 Nostalgia..... 2
Exposure and typhoid fever..... 1 Nephritis..... 3
Encephalites..... 1 Œdema of glottis..... 1
Effects of bad whiskey..... 1 Organic disease of heart..... 1
Exsection head of femur..... 1 Obstruction of tricuspid valves..... 1
Exasticulation (R) humerus..... 1 Œsophagismus..... 1
Emacination..... 1 Pyæmia..... 80
Effusion..... 1 Pneumonia, double, &c..... 187
Fractures..... 11 Prostration..... 1
Fracture of femur..... 1 Pulmonary congestion..... 3
Fracture of skull..... 2 Pulmonalis..... 1
Frozen feet..... 2 Phthisis pulmonalis..... 63
Found dead..... 1 Phthisis pulmonalis..... 14
Fever..... 15 Peritonitis..... 9
Fever, bilious..... 6 Pericarditis..... 6
Fever, remittent..... 4 Pleuro pneumonia..... 11
Fever, brain..... 1 Purpura..... 1
Fever, typhoid..... 502 Paralysis..... 1
Fever, typhoid malarial..... 59 Pleurisy..... 9
Fever, typhoid remittent..... 1 Paraplegia..... 2
Fever fraumatic..... 3 Poisoned..... 5
Fever, intermittent..... 11 Pleuritis..... 2
Fever, remittent..... 25 Partial paralysis..... 1
Fever, congestive intermittent..... 1 Phlegmanous erysipelas..... 2
Fever, continued..... 4 Pelvic abscess..... 1
Fever, malarial..... 2 Perpotation of bowels..... 1
Fever, congestive..... 14 Phlebitis..... 1
Fever, enteric..... 6 Periosties, chronic..... 1
+ +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/68_pg1_repeat1.md b/outputs/old_scans/68_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..0e48a65cff0612192c0e14a943090456f359748b --- /dev/null +++ b/outputs/old_scans/68_pg1_repeat1.md @@ -0,0 +1,54 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +CAUSES OF DEATH—Continued. + +Pistol shot 1 Shot by citizen 1 Resection 2 Typhoid pneumonia 29 Resection of humerus 1 Typhoid diarrhoea 1 Rheumatism, acute, &c 7 Tuberculosis 3 Rubicola 23 Tenatus 2 Rupture 3 Tenatus traumatic 1 Suicide 5 Tebes mesenterica 2 Softening of brain 2 Tonsilitis 1 Stabbed 2 Unknown contrabands 1,546 Syphilis 3 Ulcers 2 Shell wounds 7 Ulceration of bowels 1 Scorbutus 1 Variola 14 Scrofula 1 Variola descrita 1 Scurvy 1 Variola confluenta 18 Sun stroke 2 Variola glossites 1 Syncope 1 Variola nigra 2 Spinal meningitis 1 Vulpula, disease of heart 2 Scarlatina 1 Vulnus selopt 708 Scarlatina anguinosia 1 Wounds 6 Scarlatina maligna 1 Wound of head 2 Strangulated hernia 1 Wound of flesh 2 Sciatica 1 + +PLACES OF DEATH. + +Armory hospital 455 Home Sanitary commission 10 Angus hospital 25 Judiciary hospital 169 Butterfield hospital 3 Kalorama hospital 42 Columbian hospital 68 Lincoln hospital 476 Carver hospital 234 Lincoln barracks 2 Campbell hospital 143 Mount Pleasant hospital 207 Camp Stoneman hospital 14 Old Capitol prison 12 Camp Barry hospital 18 On furlough 17 Capitol Hill barracks 6 Potomac river 10 Cliffbourne barracks 6 Quartermaster hospital 76 Douglas hospital 182 Ricoid hospital 3 Emory hospital 174 Regimental hospital 195 Engineer depot 38 Stanton hospital 80 Finley hospital 116 Stone hospital 23 Fry barracks 11 Sherburn barracks 5 F street barracks 2 Soldiers' rest 3 Forts 129 Seminary hospital 7 Field hospitals 27 Wisewell barracks 2 Geisboro' hospital 58 Washington and D.C. 101 Harewood hospital 286 Contrabands 1,546 Total 4,981 + +True copy. + +JOHN V. FUREY. +Captain and Assistant Quartermaster. + +ASSISTANT QUARTERMASTER'S OFFICE, +Depot of Washington, Washington, D. C., July 1, 1865. + +GENERAL: In accordance with Special Orders No. 132, Headquarters Middle Military Division, Washington, D. C., June 7, 1865, I have the honor to report as follows: + +On the evening of June 8 I left Washington, D. C., for Belle Plain, where I joined Colonel Bird, of the 1st regiment 1st army corps, and proceeded to the battle-fields of the Wilderness and Spottsylvania Court House for the purpose + +of superintending the interments of the remains of Union soldiers yet unburied, and marking their burial-places for future identification. + +This work was commenced on the 12th, and completed on the 24th of that month. Careful search was made over the above-mentioned battle-fields, and the remains of all soldiers, both Union and rebel, interred, and headboards, with name, rank, and regiment, placed at each grave (with some exceptions in cases of rebels) when it was possible to identify the deceased. The words "Unknown United States soldiers, killed May 10, 1864," on a neat tablet, mark the remains of our own soldiers that could not be identified. + +On the battle-ground of the Wilderness two cemeteries were laid out, enclosed by a paling fence. Cemetery No. 1 is on the Orange Court House turnpike, about two miles from the Wilderness tavern, and contains the remains of one hundred and eight men. Cemetery No. 2 is on the Orange Court House plank road, about two and a half miles from the junction of the Orange Court House turnpike, and contains the remains of five hundred and thirty-four men. + +The sites are well adapted for the resting-place of those who fell in the vicinity, having been selected where the scenes of carnage appeared to be the greatest. It was no unusual occurrence to observe the bones of our men close to the abatis of the enemy; and in one case several skeletons of our soldiers were found in their trenches. The bones of these men were gathered from the ground where they fell, having never been interred, and by exposure to the weather for more than a year all traces of their identity were entirely obliterated. + +On the battle-field of Spottsylvania but few men were found unburied, many of them having been interred by a Mr. Sandford, who resides at Spottsylvania Court House, in compliance with an agreement to that effect with General Sherman while on his march to Washington city. Over seven hundred names were found on this battle-field, and tablets erected in memory of the deceased. + +It was my intention to remove those partly buried to a suitable site for a cemetery; but the weather being exceedingly warm, and the unpleasant odor from decayed animal matter so great as to make the removal impracticable. They were, however, carefully re-covered with earth and entirely hidden from view. + +Hundreds of graves on these battle-fields are without any marks whatever to distinguish them, and so covered with foliage that the visitor will be unable to find the last resting-places of those who have fallen until the rains and snows of winter wash from the surface the light covering of earth and expose their remains. + +The accompanying list embraces the names of officers and men to whose graves headboards have been erected. + +I am, general, very respectfully, your obedient servant, + +JAS. M. MOORE, + +Captain and Assistant Quartermaster United States Army. + +Brevet Major General M. C. MEIGS, +Quartermaster General U. S. A., Washington, D. C. + +Graves of Union prisoners at Andersonville.—Report of Captain Moore. + +WASHINGTON, Wednesday, October 18, 1865. + +The following report of Captain J. M. Moore, assistant quartermaster, who was sent to Andersonville, Ga., to mark the graves of Union prisoners for future identification, contains valuable information, in which the people are interested, and will, doubtless, be appreciated by the relatives and friends of those who have given their lives to their country: + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/69_pg1_repeat1.md b/outputs/old_scans/69_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..ea74bcde2aca4dc01d8b5667257589b5315c9d96 --- /dev/null +++ b/outputs/old_scans/69_pg1_repeat1.md @@ -0,0 +1,40 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +The Alpha. + +ENTERED AT THE POST-OFFICE AT WASHINGTON, D. C., AS SECOND-CLASS MAIL MATTER. + +Human Rights before all Laws and Constitutions.—Gerrit Smith. +The Divine Right of Every Child to be Well Born. + +VOL. VI. + +WASHINGTON, D. C., JUNE 1, 1881. + +NO. 10. + +PARENTAL LEGACIES. + +A PAPER READ BEFORE THE INSTITUTE OF HEREDITY, CONVENED IN BOSTON, MAY 25, 1881. + +CAROLINE B. WINSLOW, M. D. + +To a toil-worn reformer this goodly meeting is truly a most cheering event—a green oasis in a vast desert of perversion, ignorance and hap-hazard discord. That ere the close of the nineteenth century, this congregation of philanthropists and reformers, men and women have met, to take counsel one of another and solemnly consider the most wise and legitimate methods of improving our common humanity, the most reasonable means whereby the world may become healthier, happier, purer, truer, through a knowledge of the laws of hereditary transmission. + +Heredity means (according to Webster) descended by inheritance, ancestral, patrimonial, inheritable. But to use a more familiar definition, "The science that treats of the transmission of physical, mental and moral traits to descendants." + +Many sided and perplexing as is a successful study of our subject, with its centuries of accumulated crookedness and mystery, we believe, with the aid of inspiration and the light of science, human intelligence and beneficence will be found competent to unravel this tangled mass of evidence and patiently arrange into order, testimony of the most valuable character, and evolve lessons of wisdom that will essentially advance the interests of the human race. Of course we are only seed sowers, and can only work with the implements and materials produced by our generation. We must begin with those already born and those that will be born in our day. It will be a vast benefit to posterity if we can so enlighten the rising generation that they will realize the necessity of studying their own patrimony, and that of the one they propose selecting for life companionship. If only this is accomplished the tide of human wisdom will have turned its efforts in the right direction and the opportunity for developing the most sublime traits of human characters will be afforded. For I predict our coming heroes will not be battle-stained and blood-stained men with maimed and crippled bodies, but men and women who will be canonized for their self-renunciation and the wise ordering of their lives for the good of others, for good works, diligence and skill. + +Self-conquest will be an achievement recognized and honored by all men, and will become the power + +which shall marshal their hosts against such spiritual enemies as tyranny, selfishness, ignorance and lust. + +With such noble ends to be accomplished we look with great interest and solicitude to this new departure, this Institute of Heredity, and inquire what are the methods and plans by which such desirable results will be brought about? + +If, by familiarity with our inherited traits and an inventory of possibilities, aught is discovered that cannot be satisfactorily transmitted to prove a joy and blessing to progeny, individual responsibility will be so patent that an irremediable defeat will settle the question of parentage at once, and an heroic resolution taken that their plague-spot shall die off from the face of the earth and be known no more forever. But if by knowledge of the laws governing development and a wise application of the law of selection, whereby the virtues and defects of contemplated partners may complement each other, with the sustaining praise and stimulating joy of establishing a new grade that shall lead to a desirable pedigree, and doing one's best toward redeeming the mistakes and blunders of the past, the results cannot fail of being most happy. + +When fathers and mothers become as solicitous for the mental and moral qualities they leave behind them as they do of houses and lands, government bonds, promissory notes, articles of virtu, and other worldly and perishable possessions; when they strive to bequeath such priceless treasures as a healthy physique and well developed brain to their heirs, "the last will and testament" of progenitors will be less liable to litigation, legacies will be of more permanent value, and become objects of profound veneration. The spendthrift will not forget the sacredness of his inheritance; the man or woman tempted by appetite will possess a double incentive to resistance. That rich, pure blood, may be transmitted untainted by any voluntary self-indulgence, and what of taint or discord we detect in ourselves will become a life-work to eradicate and conquer by the persevering observance of physical and moral hygiene; that only grace, health, and beauty be handed down to crown with joy the lives of coming ages of men. Then the unfortunate victim of malformation, of feeble intellectual and moral sense, with scrofula, syphilis, or insanity poisoning his blood, will be looked after and cared for by legal but humane authority, and will not be permitted to transmit his curse to posterity. The restraint imposed by legal enactment, reason and conscience, will be the tender but effectual means used to check this class + +1881-2 Please anchor + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/6_pg1_repeat1.md b/outputs/old_scans/6_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..60808294af84f1ff2914f5ff855a36ad3b197890 --- /dev/null +++ b/outputs/old_scans/6_pg1_repeat1.md @@ -0,0 +1,21 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +Personal and confidential. + +209 East Capitol Street, +Washington, D. C. May 22, 1914. + +Hon. Theodore Roosevelt, + +Oyster Bay, New York. + +Dear Sir:- + +Ack 5/22/14. + +I am a Democrat, and have voted the straight Democratic ticket for more that 45 years, or from Greeley to Wilson, but it is my deliberate judgment that you will be the next man, if you keep your health, to be elected President of the United States. It is in the air, and he who runs can see, hear and feel it. I attended the meeting of Judge Lindsey and the Colorado women last night at the Armory on G street in this city. The meeting was an exceedingly large and enthusiastic one and ran from 8 P.M. until midnight. But one thing struck me particularly, and that was the way the mention of your name in connection with your settlement, and the way it was done of the Pennsylvania coal strike, was received. The speaker had referred in complimentary terms to President Wilson, but expressed a doubt as to whether or not he possessed the necessary amount of nerve and red blood to handle the Colorado strike situation, and then said that if you were President it would be settled and settled quickly and satisfactorily. At this point in his speech the crowd broke loose in the wildest cheers which lasted for fully a minute. It was not altogether a revelation to me, but it did show that your name was still the one great name to conjure with, and that the eyes of all the foes of Democracy were fixed upon you as the one man around which the opposition to the present administration of national affairs was rallying for the Presidential battle of 1916. I tell you this, for the reason that the papers of Washington do not mention it, but which was one of the most distinctive incidents of this really great meeting. + +Very truly yours, +Henry C. Bell + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/70_pg1_repeat1.md b/outputs/old_scans/70_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..c505d75b31db0ae11715e4d9983b9903729efc07 --- /dev/null +++ b/outputs/old_scans/70_pg1_repeat1.md @@ -0,0 +1,53 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +of population. For it will be considered "a sin to entail crime upon society, and equally a sin to make one's house a sepulcher, full of death and blight." + +There has recently come to our knowledge a family of eight idiots, all grown to men's estate, with stalwart bodies, but not sufficient mental calibre to care for their personal wants any better than in early childhood. Their father and mother are cousins. With the habits common to ignorant people, blood poisoned with whisky and tobacco, the tissues of the body built up on pork and corn; is it surprising that these old people are utterly discouraged in their poverty and the failure of all the objects of life? Would not legislation that would have interfered in preventing the marriage of such persons, or after their marriage, have interposed its beneficent restraints to have prevented these eight crimes from burdening the world have been wise and timely? + +“This is the class that are damned into the world, not born.” “It becomes the duty of scientists and reformers to see to it that this class of parasites do not drain the life of the parent tree.” + +Such are the penalties and disappointments that result from a life of ignorant sensuality and irresponsibility in many families. This may be considered an extreme case. But do we not see such results in a degree all around us? How often do we hear of good men, ministers of the Gospel and devout Christians, having wild, vicious sons and unreliable daughters, and how often is the question asked, "Why should such God-fearing families be so afflicted?" + +A great stride forward will have been taken when the religious and secular mind shall have been disabused of the popular error that God creates every child that is born, calls him forth into life by the fiat of His will. Here human responsibility is ignored by the masses and Divine Providence becomes the scape-goat for our sins and shortcomings. But this immunity does not extend to the breeding and improving of domestic animals. The farmer and stock raiser knows to a certainty that if he wishes fine cattle and spirited horses he must be wise in selection, careful to supply nutritious and abundant food and provide just enough exercise to insure the health and vigor of the female. + +This point is aptly illustrated by a correspondent in a recent number of the Woman's Journal. The writer, a wife and mother, is over-burdened by housekeeping and the care of her little children; her husband stupidly oblivious of the fact. She says: "Once we were riding; at the foot of a hill he told me to get out and walk up as his mare would foal in July. My baby would be born in August." + +He remembered to be kind to his horse and care for his colt in embryo. He knew his responsibility there, but he had no thought for his own child. I fear this is not an unusual case, for, alas, it is the experience of many wives. Another one writes: "I have no money only what I can get on the sly." Meaning if she could find small coin in her husband's pocket she would take it, if she thought he would not miss it. His children will inevitably be sly and thievish. But he feels no responsibility in the matter. They are God's children not his. + +It would make a vast difference in that man's conduct, and still more in the character of his children, if he believed himself to be a free moral agent in this matter of generation, and while holding the balance of power is largely responsible for the endowment of his children. "As he sows so shall he reap." + +We are told that God wills the salvation of all souls, but he cannot and will not save souls without human help. + +This knowledge will mark a new era in the history of human progress and reform. Men will select their wives for their vigorous health, their moral and spiritual tendencies by inheritance and the effect of personal habits of life, and the probable result to their children from combination with their own peculiarities; before they dare jeopardize the welfare of offspring, who are so helplessly dependent upon their ancestors not only for the breath of life, but for qualities that will make their lives desirable, not an intolerable burden to themselves and society; that will endow them regally, not impoverish them with discord and disease; crown them with transcendent talent, not blast them with idiocy. + +When this great day shall have dawned upon the children of men, the work of the church—Christ's church on earth—will not be the expounding of doctrine, calling upon men to save their souls by sprinkling or emersion, while they despise and neglect their bodies, but shall be the healing of the great leprosies of society, the cleansing of sensuous lives, the diminution of criminal classes, the care and education of youth by every elevating and salutary influence. Teachers and preachers must begin by casting out their own selfishness and cultivating virtue and purity in their souls, and so manifest it in their lives that from them will emanate an attractive radiance that will draw the sin-sick and heart weary unto them, to heal and bless. They must recognize physical law to be as divine and immutable as spiritual law, and impress up the minds they would direct that there can be no real virtue except when manifested through a healthy body. Therefore the attainment and preservation of physical health becomes a cardinal virtue. And above all must we steadfastly live our principles of beneficence and purity if we expect to do good to others. Especially must we live lives of sexual holiness and pure continence except for procreation, whether married or single. Sexual abuses are the great sins of our day. The social ulcer, the cancer at the heart that is draining our strength, consuming our life and vital force, defrauding little children and the cause of the increase of crime, disease, premature death and all the sorrows that blast our lives and go to make up its wastes and burdens. + +False teachers have proclaimed the doctrine of physical necessity," have wailed about "sexual starvation" and "over-population." Medical teachers and physicians have recommended marriage or concubinage as a specific for sexual diseases. All manner of protections and prevention to conceptions, with foeticide, (which often means suicide,) have been devised. Some have even professed consecration of sexuality, which proves to be another name for sensual indulgence without procreation, but to me they are all false teachers, false prophets, that cry "peace, peace, when there is no peace." + +They all lead to the same results—disgust, loathing, disease. The desecration of the God-like creative power and sacred sexual function creates a perfect pandemonium in the soul. Of it are born satiety, disgust, jealousies, contentions, nervousness, disease, and death of all that makes life sweet and desirable. Thus is Milton's allegory of the fallen angel re-enacted in our hearts and by nearly every family in the land. + +In this condition children are too often conceived, added to the rebellion of the wife against the injustice of enforced maternity, and the plotting against, or at least the desire to destroy the embryo. What wonder that we are overrun with criminals of every shade and degree, God's likeness transformed into demoniacal distortions, and the world burdened with the support of jails, penitentiaries, reformatories, insane, deaf, mute, blind and idiot asylums, with a gibbet in every township. + +All these disasters follow the desecration and profanation of the most sacred function with which we are crowned. The creative power, in combination with reason, allies us more closely to an Infinite Creator than any other gift. Every infringement of the law of continence for sensual purposes to an enlightened conscience brings its own shame, debasement, and contrition. + +Let no one say "this standard is too high;" that "it is not possible of attainment." I assure you it is. Many families are this day trying this method of living. And they report themselves as being happier and healthier, more loving and cheerful than before. + +We cannot recognize the necessity of physical expression of the sexual nature save for its legitimate and creative function. Unlike the natural physical instincts which demand food, shelter, warmth and clothing, which are necessary for the renovation of the blood and building up the waste tissues, and the growth and health of our bodies, this is under the control of our emotional nature, and should be dominated by our reason and will power, as every expression of it reduces vitality and wastes life force. No man or woman in health and symmetrically developed has any desires, but through the imagination or sympathy. Like the shedding of tears, health or happiness would not be impaired by years of abstinence, but like weeping, indulgence always depresses nervous energy. + +This doctrine of continence is the stone which all social reformers have rejected or neglected. I now present it as the chief corner-stone of the Institute of Heredity. If accepted, it will set the institute on a firm, enduring base. Storms or floods, winds or flame, nor the power of hell can never prevail against it, for it will stand upon a rock. Security and peace will dwell with wisdom within its borders, and none shall make afraid or soil its pure escutcheon with slander or evil passions. This is really the whole of salvation each soul must work out for himself. + +Brothers and sisters, I exhort you to present your bodies holy, acceptable to the Lord, which is your reasonable service. + +We should teach to others the truths we ourselves have learned. + +THE WOMEN'S NATIONAL RELIEF ASSOCIATION. + +In the autumn of 1880, plans, long considered by a few benevolently-minded women, culminated in the formation of the Women's National Relief Association, having its headquarters in Washington, D.C., the object of which is so to organize benevolent effort that the women of the nation, by concert of action, may have in readiness for any sudden or imperative necessity arising from conflagration or other disaster, epidemics, famine or war, such sanitary aid and material as the occasion calls for, and to insure their economical and equitable administration. It has also the present specific object of supplying without delay the United States Life-Saving Stations with beds, blankets, warm clothing, and other necessaries for the preservation and comfort of persons rescued from shipwreck. + +It is desired that auxiliary societies shall be formed in every State as soon as possible, in order that much needed supplementary aid may be rendered to the life-saving service during the ensuing year, and that as speedily as possible the organization may be in a condition for efficient work in the other directions alluded to. + +One hundred and ninety-six life-saving stations are established and sustained by Government. Though enough has been written of late to familiarize the public with the details of the service, probably few realize how arduous are its duties. The force employed does not admit of relief relays. The same men who patrol the beach must drag the life-saving apparatus for miles on the sandy beach, man the life-boat, carry on for hours the perilous work of rescue, and then, spent and exhausted themselves, work perhaps hours longer in preserving the lives they have saved. + +A crew frequently returns to the station, after the racking labors of a whole day or night, faint with hunger, cold, drenched through and through, cut or bruised, and spent with fatigue. They bear with them a wretched group of the rescued, sometimes with women and children in the number, livid, ragged, half naked, hurt, famished, wet and frozen. The station fire is out, or low; no food prepared; nothing ready; everything to be begun. The crews are so short handed that no one can be left to make ready for the home comers and their precious freight. The fire must be renewed, and the rescued made comfortable, with but little means to that end. There is a cot and blankets at each station for each man employed, and, as far as these will suffice, they are used for the wave-sent guests. The government supplies no clothing, but the surfmen gladly give their own only changes of dry apparel to replace the wet clothing of the rescued, themselves going wet for hours, and taking such rest as can be found on the hard boards around the station fire. Occasionally circumstances require that shipwrecked persons should be outfitted with clothing. A man came ashore from the wreck of the A.S. Davis with only the band of his shirt left on him by the raging, buffeting sea. Another was cast ashore without the vestige of a garment. One of the surfmen, from his own scanty store, supplied his wants. The Government makes no provision by which that surfman can be repaid. Is it enough that these poor + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/71_pg1_repeat1.md b/outputs/old_scans/71_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..59b77e6bd5adcb9faf6f4260bd02f1fb67541220 --- /dev/null +++ b/outputs/old_scans/71_pg1_repeat1.md @@ -0,0 +1,77 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +interchange is premeditated, as eloquence dictates, the muscular and magnetic influence of the will rivets the chain upon the heart of the hearer, who may be extremely attentive and charmed with what he hears without being a personification of love or wisdom. But raptures exert no healthful influence, unless the process which evolves them is strictly scientific in its bearings, and the true uses of life always include this characteristic. + +The riches of the universe are borne home triumphantly to the heart of the philanthropist without the wish to revel in the delight which is the consequence. The happy miner of investigation who finds jewels of inestimable value upon the point of his spade, hugs not himself with swinish delight, it is to be hoped, because the avails will enable him to gorge his senses with intoxicating pleasure, of no exalted nature, but he feels that such gems contain the fairy mystery which under his auspices will beautify his own neighborhood, give employment and relief to the poor, and the thrill of holy delight which permeates his whole frame arises from the fact that his own nature contains a happy mingling of love and wisdom in such divine proportions that the whole world can reap some benefit from his manly and benevolent exertions. + +I humbly think that the highest raptures will come to us in moments when least expected, and devotion to the loved one is best shown by contributing to his highest good. + +Raptures of all descriptions are only attendants of surpassing loveliness, who wait upon duty as the dew of labor pours from her noble brow. + +The best happiness of the heart is like the music of the well-tuned lyre, the perfume of the rose, the purple light of the evening cloud. But when emotional cravings break up or become the whole business of existence, the harmony of our being loses its best significance, and, as a great writer remarks, life ceases to retain its noblest energies, and "passes languidly into destructive and unmeaning dreams of rapture and anguish." + +ALHAZA CROFT. + +HEREDITY, HOW OPPOSED. + +The doctrine of heredity, so ably argued in late numbers of THE ALPHA, deserves further notice of the hindrances of its acceptance. I essay to discharge the office. + +The hindrances might be compressed in one—the ready acceptance of the cheap, the superficial, the pretentious; or we may specify two principal forms of the same tendency. One identifies baptism with regeneration, the sign is exalted into the thing signified, the sacramental water removes the stain and disabilities of inherited depravity. Consistently saints must be celibates. Children are forbidden to them who might most boldly claim the promise to them and to their children. Not more preposterous if a ranchman should restrain the choice of his flock and breed only from meaner cattle. + +Another portion of the Christian community ignores the law that the spiritual nurture of the child begins before its birth, or admits it only in its evil applications, as in case of the expectant mother indulging in irregular + +lar appetites or viler passions and transmitting to her offspring unwonted depravity in the same direction. The law should be recognized as equally available for good, as was found in case of Jeremiah, Isaiah and the Baptist, (Jer. i, 5; Is. xliv, 15; Luke i, 15.) Nothing exceptional here, all normal and to be expected, whenever it may be said of parents, "They were both rightous before God, walking in all the commandments and ordinances of the Lord blameless."—O. vi, 7. Despite the principles running through the Holy Writ, despite the teachings of science, philanthropy and common observation with a large portion of the Christian community, the beau ideal Christian begins life a heathen, goes astray as soon as he is born, speaking lies, though born of Christian parents, and perhaps dedicated to God in baptism, he is still accounted an alien till the revival comes along to effect his conversion. + +The utmost that parents are encouraged to hope is the early conversion of their children. Sanctification from or before birth is at most admitted a bare possibility, may be in rare cases; is not accepted as the normal and expected thing, and not expected is not realized. Under a ripened Christianity we shall not hear of the conversion, early or late, of children of Christian families. Children will be born with the germs of divine life implanted in them, to be quickened into activity. Indeed I believe that, to a hopeful extent, such is already the case, that of many Christians the practice is better than the theory, proving that a sanctified parentage assures a sanctified progeny, and that the reported conversion of children is rather the revivification of a principle afore imparted. W. W. + +“PUISSANCE OBLIGE.” + +Under the above title, the Cambridge Review of the 2d ult., in an article which well deserves attention, upon the duties of the strong towards the weak, says: + +“There exists in our community a class of persons to whom its teachings have as yet been very imperfectly applied—why, it would be hard to say, for whatever claims weakness has upon strength, they possess in a superlative degree. Mr. Lecky, in a flourish of sublime nonsense, has dubbed them ‘the priestesses of humanity,’ bearing, since some must bear it, the sin of the world. And who are these majestic priestesses? They are not women. They are children, women-children, at least when they first assume their sacred functions. Their are young girls in their teens, that is, of the age when our daughters and sisters have hardly got into ‘long dresses,’ when they are still at school, or in the school-room, when they prefer a circus or a pantomime—the babies!—to a party ‘where you have to be so proper, you know.’ Of such are the ‘priestesses of humanity.’ + +“With this difference. That they have never had a father to romp with them, or a brother to protect them from a whisper of insult. That from the first, life has meant to them hard work, privation, severity, servitude. That for many of them—‘not so much born as damned into the world’—it has meant education in evil and encouragement, nay, compulsion to vice. That the happiest of them have not been sheltered from temptation; + +that the wisest of them are very ignorant and childish; that the richest of them are very poor. + +“And what have we done for our women-children? * * * + +“This is what we have done for the women-children, who might have been our own. + +“We have taught them that a first downward step is irretrievable, and stamps upon them a brand which nothing can efface. We have goaded them on to fresh evil with all the force of cruel contempt or frigid indifference. We have herded them together in one outcast class, without distinction of character or experience in sin. We have hardened them, often in periods incredibly short, unsexed them, made of them drunkards, blasphemers, tempters, fiends in human form. We have done this. + +“Even when we have had too much respect for womanhood and for ourselves, to heap fresh ignominy upon them, we have been responsible for their blood, inasmuch as we have stood aloof, and have deemed with a cynical apathy, or with the fastidious shrinking of a mistaken refinement, that their fate did not concern us. + +“‘Upon the soul of every individual amongst us did a portion of guilt rest, as long as the slave trade remained legal,’ said Coleridge, and as long as society's laws, whether sanctioned by act of Parliament or no, ordain a yearly holocaust of thousands of its weakest members, so long will their blood be upon the head of every responsible member of society. + +“Yet there is a change coming. There is on the horizon a cloud scarcely bigger than a man's hand which is destined to grow and grow till it overspreads the sky. It is the awakening of women to their responsibilities toward their young sisters. The truths that are dawning with irresistible but gradual force upon the reasoning minds of men have laid hold with a sudden fiery grip of the impassioned spirits of women, and caused the scales of age-long custom, the ‘stiffening crust’ of tradition to fall from their eyes. They are going forth to raise the newly-fallen, to melt the hardened with love, to wipe out a past of sickening horror in a future of hope and calm; they are moreover working socially for justice, for honesty, for a loftier purity, for the practical extension of the kingdom of Christ.” + +“Faust says : + +‘The Woman-Soul leadeth us +Upward and on.’ + +“Not that we are to get a woman to smuggle us into heaven when we are sick of our follies and sins; not that we are to do our religion and morality by deputy, admiring women's purity and goodness with sentimental wistfulness, and contenting ourselves, for our own part, with ‘half the virtues’; but that we are to defer to the weaker, to surrender to the needy and the oppressed, to do battle for the poor, to aspire with the pure in heart, to remember: ‘Puissance oblige.’”—The Shield. + +“SEXUAL ORGANISM AND ITS HEALTHFUL MANAGEMENT.” + +James C. Jackson, M. D., in his "Sexual Organism and its Healthful Management," in a chapter all ought + +to read, page 258, says: "I am satisfied, from a thorough study of the organic relation of the sexes, that the faculty of amativeness has a two-fold purpose, and should be always gratified by either sex from this point." + +But I am not "satisfied" that this is so, nor has the world ever had a fair chance to test the other side of theory. Men and women, like plants and animals, have gone on for millions, and perhaps billions of years increasing and multiplying whenever inclination and circumstances favored such a course. A few nunneries, cloisters and Shaker villages have made ascetic continence a religious rite and a martyrdom, but where are the societies who have tried pure, affectional, loving continence? Where can we find a community of men and women who have only had sexual commerce for purposes of procreation? and where are the generations that have had continent parents, grandparents, and great grandparents? Alas! echo answers where? And till we have just one such, this question will have been experimentally tested on one side only. + +Men plead for moderate indulgence, (saying that continence will produce a race of apathetic, dull, lifeless, pale, sad-looking people—sexless and soulless.) But how do they know? The few Alphaites who have lived continently speak in eulogies of its effects upon themselves and all they know to have tried it. It makes them kind, loving, charitable and unselfish, strong, vigorous and young, even as plants and trees are stronger, more vigorous and long-lived, when not allowed to produce fruit. It is an up-hill work, I will allow, this one of unteaching the old, and ingraining into the mind the new. Women, wine and feastings—next to wars—seemed to be the greatest luxuries of antiquity. Not woman as she should be—man's equal, his helper and his mother; but as his slave, his subject and his plaything—one who ministered unto and gave him pleasure. The Arabian Nights and Shakespeare, and all old-time books, and indeed, all novels, even of today, place this question of sex prominently before us as if it was first and foremost in all hearts. We shall need a newer and cleaner literature ere the world will become pure and clean. But if here and there one is saved; if here and there one ray of truth reaches a single mind, our labor will not be lost, and that this is being accomplished every mail that reaches me bears record. Broken-down and despairing wives, passion and lust-cursed children, and pale, nerveless and debilitated men, all send in sad and bitter testimonies as to the great need of the work Alphaism is endeavoring to do, and now and then comes a glad, jubilant song from a saved soul that cheers and encourages to more and better work in the future, and assures us that all is not seed sown on stony ground. + +“The time has come to preach soul; +No meager shred—the manly whole; +Let agitation come; who fears? +We need a flood; the filth of years +Has gathered round us. Roll then on; +What cannot stand had best be gone.” + +ELMINA D. SLENKER. + +SNOWVILLE, PULASKI CO., VA. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter. diff --git a/outputs/old_scans/72_pg1_repeat1.md b/outputs/old_scans/72_pg1_repeat1.md new file mode 100644 index 0000000000000000000000000000000000000000..bc652fc50cb78c3aff825b56cdee345d44eaa90e --- /dev/null +++ b/outputs/old_scans/72_pg1_repeat1.md @@ -0,0 +1,227 @@ +> This page was read from its image by a model (olmocr); the PDF holds no text for it.[^inferred] + +LIST OF PAMPHLETS +FOR SALE +At the Office of THE ALPHA, No. 1 Grant Place +Washington, D. C. : +THE RELATION OF THE MATERNAL FUNC- +TION TO THE WOMAN INTELLECT. +BY AUGUSTA COOPER BRISBE. +Price 10 cents. + +PLAIN, SOBER TALK ABOUT OUR SEXUAL NATURES. +BY N. E. BOYD. +Price 10 cents. + +PRE-NATAL CULTURE. +BY A. E. NEWTON. + +This pamphlet of 67 pages contains scientific suggestions to parents relative to systematic methods of moulding the character of children before birth. +Price 25 cents. + +THE RELATION OF THE SEXES. +BY FREDERICK A. HINCKLEY. +Price 10 cents. + +THE NEW LIFE. +BY FREDERICK A. HINCKLEY. +Price 10 cents. + +MOTHER TRUTH'S MELODIES. +BY MRS. DR. E. P. MILLER. +Price one dollar. + +FATHER'S ADVICE TO EVERY BOY +AND +MOTHER'S ADVICE TO EVERY GIRL. +BY MRS. DR. E. P. MILLER. + +VITAL FORCE. +BY DR. E. P. MILLER. +Price 30 cents. + +CHRONIC AND NERVOUS DISEASES OF +WOMEN. +BY DR. ROSCH. +Price 25 cents. + +THE DUTIES +OF THE +MEDICAL PROFESSION +CONCERNING + +PROSTITUTION + +Being the Oration before the Maine Medical Association at its Annual Meeting, 12th of June, 1878. + +BY FREDERIC HENRY GERRISH, M. D., +Price 25 cents. + +MOTHERHOOD +AND +MOTHER'S AID. +BY MRS. L. B. CHANDLER. +Price 10 cents each. + +THE WOMAN QUESTION, + +BY ELIZA BURT GAMBLE, + +Is a pamphlet of 26 pages, written in a clear, logical style. The argument for the higher education and political equality with men is irrefutable, and claims the attention of all progressiv and philanthropic minds. On'y by the equality and emancipation of woman, can a race of noblemen inhabit the earth. Send for a copy. + +50 cents, 10 cents; 12 copies for \$1; \$9 per 100. + +A LIBERAL DISCOUNT TO THE TRADE. + +CANCER AT THE HEART; + +A DISCOURSE + +BY + +FREDERIC A. HINCKLEY, +Resident Minister, Free Religious Society, Providence, Rhode Island. + +Price 10 cents +For sale at— + +No. 1 Grant Place, +Washington, D. C. + +THE MYSTERY, AND HIGHERTO AND BEYOND +Two essays read before the Washington Moral Education Society. + +BY MRS. EVELYN L. MASON. + +These essays are the result of ten years' study of the religions of all nations and all ages, and shows how constant has been the effort to recognize the feminine element in religious worship, and just as they have succeeded has civilization advanced and each time the aggressive force of man has crushed the idea, humanity has fallen back into darkness and barbarism. + +Price 15 cents. For sale at the office of THE ALPHA, 1 Grant Place, Washington, D. C. + +THE BETTER WAY: +AN +Appeal to men in behalf of Human Culture +through a wiser parentage. +BY +A. E. NEWTON. +Price 25 cents. For sale at No. 1 Grant Place, +Washington, D. C. + +THE WOMAN'S JOURNAL. +A Weekly Newspaper, published every Saturday in Boston, devoted to the interests of Woman—to her educational, industrial, legal and political Equality, and especially to her right of Suffrage. +LUCY STONE. Editor. + +T. W. HIGGINSON,...... +JULIA WARD HOWE,...... +MARY A. LIVERMORE,...... +H. B. BLACKWELL,...... +Editorial +Contributors. + +Mrs. FRANCES D. GAGE,...... +Mrs. H. M. T. CUTLER,...... +Occasional Contributors. + +SUSIE C. VOGL, Advertising Manager. + +TERMS—\$2.50 a year, \$1.25 for six months, 65 cents for three months, in advance, 6 cents for single copy. + +This is the only weekly paper of the kind east of the Rocky Mountains. It furnishes a medium of communication for those interested in the various phases of the questions to which it is devoted, and hence is invaluable as a bond of union, and source of intelligence on its special topics. + +BOSTON OFFICE—No. 5 Park Street, where copies are for sale and subscriptions received. + +CLUB RATES—10 copies one year, \$20.00. + +Specimen copies sent on receipt of two cent stamp for postage + +BURNZ PHONIC SHORTHAND. + +THE VERY BEST. + +A complete Self-instructor in the latest and best mode of stenographic reporting. + +The text-book used in the famous Cooper Union short-hand classes. + +Sent, postpaid, for \$1.00. + +HELP FOR YOUNG REPORTERS. + +Containing full directions for taking and writing out short-hand notes, no matter what system is used.—Sent for 50 cents. + +Proof corrected for authors who desire their works issued in any form of simplified spelling, without new letters. + +BURNZ & CO., + +PUBLISHERS AND DEALERS IN + +Fonographic and Fonetic works and Reporters' materials. +24 Clinton Place, New York. + +THE TOBACCO VICE, +WITH SUGGESTIONS HOW TO OVERCOME + +IT. + +BY HANNAH MCL. SHEPARD. + +Price 10 cents. For sale at No. 1 Grant Place, +Washington, D. C. + +A PRIVATE LETTER +TO PARENTS, PHYSICIANS AND MEN PRINCIPALS OF SCHOOLS. + +Price 10 cents. +BY SAXON. + +A physiological treatise on sexual ethics and the conservation of the spermatic sections. + +ALPHA UNDERGARMENTS. + +Constructed in accordance with physiological principles, covering the body evenly from neck to waist and ankles—made from warm, soft and elastic fabric. + +Samples of material with price list sent by mail. + +Orders accompanied by cash will receive prompt attention. + +The garment for women is the result of careful study for years, and while the odd and peculiar construction of pockets in vest is acknowledged, that feature is earnestly presented as of great importance in the arrangement of sanitary clothing. For children's wear the "Alpha" is not surpassed by any garment in the market. + +ECRU ALPHA GARMENTS FOR SPRING AND SUMMER WEAR. + +Fabric—heavy and light English Lisle Thread; half bleached, which insures unusual durability in underwear of Summer grades. + +Delicate in texture, made to fit the figure perfectly, of excellent workmanship. An unusual opportunity to clothe the body lightly, comfortably and healthfully during warm weather. + +Address +ALPHA MANUFACTURING CO., +Woburn, Mass. + +THE MORAL EDUCATION SOCIETY OF +Washington will meet the last Saturday of each month at No. 27 Grant Place, and every Thursday afternoon at the same place, Jerusha G. Joy will be happy to meet any ladies informally that may be interested in Social Science or Moral Reform. All are invited. + +OFFICERS. +Dr. CAROLINE R. WINSLOW. President. +Mrs. ELLEN M. O'CONNOR,} +Dr. SUSAN A. EDSON,} +Vice Presidents. +E. L. MASON. +MARY E. HART. Rec. Secretary. +ELLEN H. SHELDON. Cor. Secretary. +JERUSHA G. JOY. Treasurer. +RUTH C. DENISON. Auditor. + +GRACE ROBERTS, M. D., + +204 FIFTH SREEET, S. E., +WASHINGTON, D. C. +Office Hours: 8 to 11 a. m.; 4 to 6 p. m. + +SUSAN A EDSON, M. D., + +NO. 1308 I STREET +WASHINGTON, D. C. + +CAROLINE B. WINSLOW. M. D., +NO. 1 GRANT PLACE, +WASHINGTON, D. C. +Office hours: 9 a. m. to 12 m. + +[^inferred]: Marked text was read from the page image or inferred by a model, not taken from the document's own text. See truedoc.inferred in the front matter.