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README.md
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- Code: https://github.com/icon-lab/ACE-LoRA
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- Paper: https://arxiv.org/pdf/2603.17079
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license: apache-2.0
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tags:
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- medical-imaging
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- vision-language-model
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- vlm
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- lora
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- graph-neural-networks
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- zero-shot
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datasets:
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- physionet/mimic-cxr-jpg
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metrics:
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- accuracy
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# ACE-LoRA: Graph-Attentive Context Enhancement for Medical VLMs
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<div align="center">
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<a href="https://arxiv.org/pdf/2603.17079">
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<img src="https://img.shields.io/badge/arXiv-2603.17079-b31b1b.svg" alt="arXiv">
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</a>
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</div>
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**ACE-LoRA** is a parameter-efficient adaptation framework designed for generalist medical Vision-Language Models (VLMs). It addresses the specialization–generalization trade-off by integrating Low-Rank Adaptation (LoRA) with a novel **Attention-based Context Enhancement Hypergraph Neural Network (ACE-HGNN)**.
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## Model Description
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Existing medical VLMs often struggle to balance broad semantic understanding with fine-grained diagnostic cues. ACE-LoRA bridges this gap by adding only **$0.95M$** trainable parameters to frozen image-text encoders.
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### Key Features:
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* **ACE-HGNN Module:** Captures higher-order contextual interactions beyond pairwise similarity, enriching global representations with localized diagnostic details.
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* **Label-Guided InfoNCE Loss:** A specialized loss formulation designed to suppress false negatives between semantically related image-text pairs, improving cross-modal alignment.
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* **Efficiency:** Achieves state-of-the-art (SOTA) performance across multiple domains while keeping the backbone frozen.
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> [!NOTE]
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> **Abstract:** ACE-LoRA integrates LoRA modules into frozen image-text encoders and introduces a Hypergraph Neural Network to capture contextual interactions. Despite its minimal parameter footprint, it consistently outperforms SOTA medical VLMs and PEFT baselines in zero-shot classification, segmentation, and detection tasks.
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---
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## Technical Specifications
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### Architecture Overview
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The model utilizes a frozen CLIP-like backbone enhanced with:
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1. **LoRA Adapters:** Plotted within the transformer layers of the vision and text encoders.
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2. **ACE-HGNN:** A hypergraph-based module that processes localized features to capture complex diagnostic patterns.
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### Environment Setup
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The framework was developed using `Python 3.10.18` and `PyTorch 2.1.0` with `CUDA 11.8`.
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```bash
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conda create -n ace_lora python=3.10.18
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conda install pytorch==2.1.0 torchvision==0.16.0 torchaudio==2.1.0 pytorch-cuda=11.8 -c pytorch -c nvidia
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pip install -r requirements.txt
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- Code: https://github.com/icon-lab/ACE-LoRA
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- Paper: https://arxiv.org/pdf/2603.17079
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