{
  "systems": [
    "pan_skin",
    "hematopoiesis",
    "pancreas"
  ],
  "eff_dims": {
    "pan_skin": {
      "K": 13,
      "effective_dim": 11.075447082519531,
      "cos_offdiag_mean": -0.020954914391040802,
      "cos_offdiag_std": 0.11849680542945862,
      "cos_offdiag_max": 0.29122981429100037,
      "cos_offdiag_min": -0.34952273964881897
    },
    "hematopoiesis": {
      "K": 15,
      "effective_dim": 11.32563304901123,
      "cos_offdiag_mean": 0.002725333906710148,
      "cos_offdiag_std": 0.15220414102077484,
      "cos_offdiag_max": 0.6192497611045837,
      "cos_offdiag_min": -0.44832512736320496
    },
    "pancreas": {
      "K": 20,
      "effective_dim": 10.8522367477417,
      "cos_offdiag_mean": 0.03679059073328972,
      "cos_offdiag_std": 0.20739242434501648,
      "cos_offdiag_max": 0.4839359223842621,
      "cos_offdiag_min": -0.5196306109428406
    }
  },
  "null_cross_cos_mean": 0.00515016021229889,
  "null_cross_cos_std": 0.08944799549034006,
  "obs_cross_cos_mean": -0.004553857784824668,
  "obs_cross_cos_std": 0.09070717160395421,
  "obs_cross_cos_max": 0.26673153042793274,
  "top10_pos_pairs": [
    {
      "sys_a": "pan_skin",
      "class_a": "granular",
      "sys_b": "pancreas",
      "class_b": "endothelial",
      "cos": 0.26673153042793274
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "T-cell",
      "sys_b": "pancreas",
      "class_b": "beta",
      "cos": 0.23246313631534576
    },
    {
      "sys_a": "pan_skin",
      "class_a": "sebaceous",
      "sys_b": "pancreas",
      "class_b": "mesenchyme",
      "cos": 0.22086213529109955
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "basophil-mast",
      "sys_b": "pancreas",
      "class_b": "exocrine",
      "cos": 0.21516495943069458
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "MPP",
      "sys_b": "pancreas",
      "class_b": "adult-beta",
      "cos": 0.21175406873226166
    },
    {
      "sys_a": "pan_skin",
      "class_a": "HF-placode",
      "sys_b": "hematopoiesis",
      "class_b": "endothelial",
      "cos": 0.20595994591712952
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "T-cell",
      "sys_b": "pancreas",
      "class_b": "endothelial",
      "cos": 0.20566368103027344
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "macrophage",
      "sys_b": "pancreas",
      "class_b": "ductal",
      "cos": 0.20559315383434296
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "megakaryocyte",
      "sys_b": "pancreas",
      "class_b": "mesenchyme",
      "cos": 0.20387932658195496
    },
    {
      "sys_a": "pan_skin",
      "class_a": "fibroblast-papillary",
      "sys_b": "pancreas",
      "class_b": "endocrine-progenitor",
      "cos": 0.19662468135356903
    }
  ],
  "top10_neg_pairs": [
    {
      "sys_a": "pan_skin",
      "class_a": "HF-placode",
      "sys_b": "hematopoiesis",
      "class_b": "T-cell",
      "cos": -0.21106307208538055
    },
    {
      "sys_a": "pan_skin",
      "class_a": "melanoblast",
      "sys_b": "hematopoiesis",
      "class_b": "basophil-mast",
      "cos": -0.21275341510772705
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "basophil-mast",
      "sys_b": "pancreas",
      "class_b": "immune",
      "cos": -0.22489789128303528
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "LT-HSC",
      "sys_b": "pancreas",
      "class_b": "endocrine-progenitor",
      "cos": -0.22823907434940338
    },
    {
      "sys_a": "pan_skin",
      "class_a": "basal-IFE",
      "sys_b": "pancreas",
      "class_b": "alpha_progenitor",
      "cos": -0.2297169268131256
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "pro-B",
      "sys_b": "pancreas",
      "class_b": "gamma",
      "cos": -0.2377726435661316
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "basophil-mast",
      "sys_b": "pancreas",
      "class_b": "beta",
      "cos": -0.2504867613315582
    },
    {
      "sys_a": "hematopoiesis",
      "class_a": "basophil-mast",
      "sys_b": "pancreas",
      "class_b": "acinar",
      "cos": -0.25345271825790405
    },
    {
      "sys_a": "pan_skin",
      "class_a": "basal-IFE",
      "sys_b": "pancreas",
      "class_b": "delta",
      "cos": -0.2774435877799988
    },
    {
      "sys_a": "pan_skin",
      "class_a": "immune",
      "sys_b": "pancreas",
      "class_b": "beta",
      "cos": -0.2867254912853241
    }
  ]
}