scPTR / src /scptr /datasets /_dentate_gyrus.py
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"""Dentate gyrus neurogenesis dataset."""
from __future__ import annotations
from pathlib import Path
import anndata as ad
from anndata import AnnData
def dentate_gyrus() -> AnnData:
"""Load the dentate gyrus neurogenesis dataset.
This dataset contains ~2,900 cells from mouse hippocampal
dentate gyrus (Hochgerner et al. 2018), commonly used
for RNA velocity benchmarking.
Returns
-------
AnnData with unspliced and spliced layers.
"""
cache_path = Path.home() / ".cache" / "scptr" / "dentate_gyrus.h5ad"
if cache_path.exists():
return ad.read_h5ad(cache_path)
from ._registry import fetch
path = fetch("dentate_gyrus.h5ad")
return ad.read_h5ad(path)