diff --git a/.pytest_cache/.gitignore b/.pytest_cache/.gitignore
new file mode 100644
index 0000000000000000000000000000000000000000..bc1a1f6167d09c909aad37280b760bb715d0f1da
--- /dev/null
+++ b/.pytest_cache/.gitignore
@@ -0,0 +1,2 @@
+# Created by pytest automatically.
+*
diff --git a/.pytest_cache/CACHEDIR.TAG b/.pytest_cache/CACHEDIR.TAG
new file mode 100644
index 0000000000000000000000000000000000000000..fce15ad7eaa74e5682b644c84efb75334c112f95
--- /dev/null
+++ b/.pytest_cache/CACHEDIR.TAG
@@ -0,0 +1,4 @@
+Signature: 8a477f597d28d172789f06886806bc55
+# This file is a cache directory tag created by pytest.
+# For information about cache directory tags, see:
+# https://bford.info/cachedir/spec.html
diff --git a/.pytest_cache/README.md b/.pytest_cache/README.md
new file mode 100644
index 0000000000000000000000000000000000000000..b89018ced91c0a8af7f3f23ce8901870da89f3a0
--- /dev/null
+++ b/.pytest_cache/README.md
@@ -0,0 +1,8 @@
+# pytest cache directory #
+
+This directory contains data from the pytest's cache plugin,
+which provides the `--lf` and `--ff` options, as well as the `cache` fixture.
+
+**Do not** commit this to version control.
+
+See [the docs](https://docs.pytest.org/en/stable/how-to/cache.html) for more information.
diff --git a/.pytest_cache/v/cache/lastfailed b/.pytest_cache/v/cache/lastfailed
new file mode 100644
index 0000000000000000000000000000000000000000..5378078817ad3def28c1e49106dbe4c4a30b91e9
--- /dev/null
+++ b/.pytest_cache/v/cache/lastfailed
@@ -0,0 +1,3 @@
+{
+ "tests/test_beta_groupby.py::test_groupby_consensus_is_median": true
+}
\ No newline at end of file
diff --git a/.pytest_cache/v/cache/nodeids b/.pytest_cache/v/cache/nodeids
new file mode 100644
index 0000000000000000000000000000000000000000..d7cc93a362ad1fe2191b17b1970a82ac5fa49166
--- /dev/null
+++ b/.pytest_cache/v/cache/nodeids
@@ -0,0 +1,110 @@
+[
+ "tests/test_benchmark.py::test_are_enrichment",
+ "tests/test_benchmark.py::test_correlate_no_overlap",
+ "tests/test_benchmark.py::test_correlate_with_halflives",
+ "tests/test_benchmark.py::test_cross_dataset_consistency",
+ "tests/test_benchmark.py::test_enrichment_barplot",
+ "tests/test_benchmark.py::test_halflife_scatter",
+ "tests/test_benchmark.py::test_nmd_enrichment",
+ "tests/test_benchmark.py::test_subsampling_robustness",
+ "tests/test_beta.py::test_estimate_beta",
+ "tests/test_beta.py::test_estimate_beta_quantile",
+ "tests/test_beta_groupby.py::test_groupby_consensus_is_clipped_median",
+ "tests/test_beta_groupby.py::test_groupby_consensus_is_median",
+ "tests/test_beta_groupby.py::test_groupby_missing_column_raises",
+ "tests/test_beta_groupby.py::test_groupby_produces_varm",
+ "tests/test_beta_groupby.py::test_groupby_single_group_matches_global",
+ "tests/test_datasets.py::test_dentate_gyrus_download",
+ "tests/test_datasets.py::test_herzog2017_halflives",
+ "tests/test_datasets.py::test_pancreas_download",
+ "tests/test_datasets.py::test_schofield2018_halflives",
+ "tests/test_deep_data.py::TestGetLibrarySizes::test_correct_sums",
+ "tests/test_deep_data.py::TestGetLibrarySizes::test_missing_layer_raises",
+ "tests/test_deep_data.py::TestGetLibrarySizes::test_positive",
+ "tests/test_deep_data.py::TestGetLibrarySizes::test_shapes",
+ "tests/test_deep_data.py::TestSetupDataloaders::test_batch_contents",
+ "tests/test_deep_data.py::TestSetupDataloaders::test_no_overlap",
+ "tests/test_deep_data.py::TestSetupDataloaders::test_reproducible",
+ "tests/test_deep_data.py::TestSetupDataloaders::test_returns_four",
+ "tests/test_deep_data.py::TestSetupDataloaders::test_stratified_split",
+ "tests/test_deep_distributions.py::TestLogNBPositive::test_batch_consistency",
+ "tests/test_deep_distributions.py::TestLogNBPositive::test_gradient_flows",
+ "tests/test_deep_distributions.py::TestLogNBPositive::test_higher_theta_less_variance",
+ "tests/test_deep_distributions.py::TestLogNBPositive::test_non_positive",
+ "tests/test_deep_distributions.py::TestLogNBPositive::test_output_shape",
+ "tests/test_deep_distributions.py::TestLogNBPositive::test_peak_at_mean",
+ "tests/test_deep_guide.py::TestExtractLatent::test_deterministic",
+ "tests/test_deep_guide.py::TestExtractLatent::test_no_nans",
+ "tests/test_deep_guide.py::TestExtractLatent::test_shapes",
+ "tests/test_deep_guide.py::TestPosteriorGamma::test_more_samples_lower_variance_of_mean",
+ "tests/test_deep_guide.py::TestPosteriorGamma::test_no_nans",
+ "tests/test_deep_guide.py::TestPosteriorGamma::test_positive_values",
+ "tests/test_deep_guide.py::TestPosteriorGamma::test_shapes",
+ "tests/test_deep_model.py::TestDeepPTR::test_backward",
+ "tests/test_deep_model.py::TestDeepPTR::test_forward_loss",
+ "tests/test_deep_model.py::TestDeepPTR::test_get_latent",
+ "tests/test_deep_model.py::TestDeepPTR::test_kl_weight_zero",
+ "tests/test_deep_model.py::TestDeepPTR::test_reparameterize_stochastic",
+ "tests/test_deep_model.py::TestEncoder::test_different_inputs_different_outputs",
+ "tests/test_deep_model.py::TestEncoder::test_output_shapes",
+ "tests/test_deep_model.py::TestKineticDecoder::test_beta_is_not_cell_specific",
+ "tests/test_deep_model.py::TestKineticDecoder::test_mu_scales_with_library_size",
+ "tests/test_deep_model.py::TestKineticDecoder::test_output_shapes",
+ "tests/test_deep_model.py::TestKineticDecoder::test_positive_outputs",
+ "tests/test_deep_synthetic.py::TestCICoverage::test_perfect_coverage",
+ "tests/test_deep_synthetic.py::TestCICoverage::test_returns_fraction",
+ "tests/test_deep_synthetic.py::TestCICoverage::test_zero_variance_coverage",
+ "tests/test_deep_synthetic.py::TestGammaRecovery::test_global_mode",
+ "tests/test_deep_synthetic.py::TestGammaRecovery::test_perfect_recovery",
+ "tests/test_deep_synthetic.py::TestGammaRecovery::test_random_is_low",
+ "tests/test_deep_synthetic.py::TestGenerateKineticData::test_cell_types",
+ "tests/test_deep_synthetic.py::TestGenerateKineticData::test_non_negative_counts",
+ "tests/test_deep_synthetic.py::TestGenerateKineticData::test_reproducible",
+ "tests/test_deep_synthetic.py::TestGenerateKineticData::test_shapes",
+ "tests/test_deep_synthetic.py::TestGenerateKineticData::test_sparsity",
+ "tests/test_deep_synthetic.py::TestGenerateKineticData::test_truth_keys",
+ "tests/test_deep_synthetic.py::TestGenerateKineticData::test_truth_shapes",
+ "tests/test_deep_synthetic.py::TestLatentRecovery::test_perfect_recovery",
+ "tests/test_deep_synthetic.py::TestLatentRecovery::test_random_is_lower",
+ "tests/test_deep_trainer.py::TestTrainer::test_early_stopping",
+ "tests/test_deep_trainer.py::TestTrainer::test_fit_runs",
+ "tests/test_deep_trainer.py::TestTrainer::test_history_fields",
+ "tests/test_deep_trainer.py::TestTrainer::test_kl_warmup",
+ "tests/test_deep_trainer.py::TestTrainer::test_loss_decreases",
+ "tests/test_gamma.py::test_estimate_gamma",
+ "tests/test_gamma.py::test_gamma_clipping",
+ "tests/test_gamma.py::test_gamma_requires_beta",
+ "tests/test_gamma_dynamic.py::test_dynamic_mode_logs_params",
+ "tests/test_gamma_dynamic.py::test_dynamic_mode_produces_gamma",
+ "tests/test_gamma_dynamic.py::test_dynamic_requires_velocity_layer",
+ "tests/test_gamma_dynamic.py::test_steady_state_mode_default",
+ "tests/test_gamma_dynamic.py::test_unknown_mode_raises",
+ "tests/test_integration.py::test_full_pipeline",
+ "tests/test_integration.py::test_network_inference",
+ "tests/test_network_priors.py::test_list_known_rbps",
+ "tests/test_network_priors.py::test_load_motif_priors_valid",
+ "tests/test_network_priors.py::test_load_motif_priors_validates_columns",
+ "tests/test_network_priors.py::test_network_prior_logs_has_prior",
+ "tests/test_network_priors.py::test_network_with_priors",
+ "tests/test_network_priors.py::test_network_without_priors_unchanged",
+ "tests/test_plotting.py::test_gamma_heatmap",
+ "tests/test_plotting.py::test_gamma_violin",
+ "tests/test_plotting.py::test_phase_portrait",
+ "tests/test_plotting.py::test_pt_comparison",
+ "tests/test_plotting.py::test_pt_umap",
+ "tests/test_plotting.py::test_pt_velocity_embedding",
+ "tests/test_plotting.py::test_pt_velocity_stream",
+ "tests/test_plotting.py::test_tf_ptf_scatter",
+ "tests/test_preprocessing.py::test_filter_cells",
+ "tests/test_preprocessing.py::test_filter_genes",
+ "tests/test_preprocessing.py::test_neighbors",
+ "tests/test_preprocessing.py::test_normalize_layers",
+ "tests/test_preprocessing.py::test_smooth_fixed_bandwidth",
+ "tests/test_preprocessing.py::test_smooth_layers",
+ "tests/test_pt_states.py::test_pt_states",
+ "tests/test_pt_states.py::test_rank_pt_genes",
+ "tests/test_readwrite.py::test_read_h5ad_no_warning_with_layers",
+ "tests/test_readwrite.py::test_read_h5ad_warns_missing_layers",
+ "tests/test_readwrite.py::test_validate_layers_warns_partial",
+ "tests/test_variance.py::test_variance_decomposition"
+]
\ No newline at end of file
diff --git a/analyses/download_eclip.py b/analyses/download_eclip.py
new file mode 100644
index 0000000000000000000000000000000000000000..72fbd5616fda5b9c7395247bbdc2aab8ed79b853
--- /dev/null
+++ b/analyses/download_eclip.py
@@ -0,0 +1,451 @@
+#!/usr/bin/env python3
+"""
+Download ENCODE eCLIP data for specific RBPs and extract gene-level targets.
+
+Steps:
+1. Query ENCODE REST API for eCLIP experiments per RBP
+2. Download IDR-merged peak files (GRCh38, bed narrowPeak)
+3. Map peak coordinates to genes using Ensembl gene annotations (via pybiomart)
+4. Save result as CSV: rbp, target_gene
+
+For RBPs without direct ENCODE eCLIP data, close family members are used
+as proxies where available (e.g., TRA2A for TRA2B, MBNL1 for MBNL2).
+
+Author: auto-generated
+"""
+
+import os
+import sys
+import time
+import gzip
+import bisect
+import logging
+from collections import defaultdict
+
+import requests
+import pandas as pd
+from pybiomart import Server
+
+# ---------------------------------------------------------------------------
+# Configuration
+# ---------------------------------------------------------------------------
+
+# Primary RBPs requested by the user
+RBPS = [
+ "HNRNPA1", "YBX1", "ELAVL1", "SRSF3", "RBFOX2", "FUS",
+ "HNRNPD", "CELF2", "MATR3", "HNRNPC", "HNRNPU", "RBFOX3",
+ "ELAVL3", "ELAVL4", "ZFP36L1", "TRA2B", "MBNL2",
+]
+
+# Mapping from requested RBP -> ENCODE target label.
+# Where the exact gene is not in ENCODE eCLIP, we use a closely related
+# family member as a proxy. These are noted in ENCODE_LABEL_NOTE.
+ENCODE_LABEL = {
+ "HNRNPA1": "HNRNPA1",
+ "YBX1": None, # Not in ENCODE eCLIP (YBX3 is, but too divergent)
+ "ELAVL1": "ELAVL1",
+ "SRSF3": None, # Not in ENCODE eCLIP
+ "RBFOX2": "RBFOX2",
+ "FUS": "FUS",
+ "HNRNPD": None, # Not in ENCODE eCLIP
+ "CELF2": None, # Not in ENCODE eCLIP
+ "MATR3": "MATR3",
+ "HNRNPC": "HNRNPC",
+ "HNRNPU": "HNRNPU",
+ "RBFOX3": None, # Not in ENCODE eCLIP
+ "ELAVL3": None, # Not in ENCODE eCLIP (ELAVL1 too divergent in targets)
+ "ELAVL4": None, # Not in ENCODE eCLIP
+ "ZFP36L1": None, # Not in ENCODE eCLIP
+ "TRA2B": "TRA2A", # TRA2A is close paralog, same eCLIP binding profile
+ "MBNL2": "MBNL1", # MBNL1 is close paralog
+}
+
+# Notes about proxy usage
+ENCODE_LABEL_NOTE = {
+ "TRA2B": "proxy:TRA2A",
+ "MBNL2": "proxy:MBNL1",
+}
+
+OUTPUT_CSV = "/home/bcheng/scPTR/src/scptr/benchmark/data/eclip_targets.csv"
+
+ENCODE_BASE = "https://www.encodeproject.org"
+ENCODE_HEADERS = {"Accept": "application/json"}
+
+# Sleep between ENCODE API requests (seconds)
+REQUEST_DELAY = 0.3
+
+logging.basicConfig(
+ level=logging.INFO,
+ format="%(asctime)s [%(levelname)s] %(message)s",
+)
+log = logging.getLogger(__name__)
+
+
+# ---------------------------------------------------------------------------
+# Step 1: Build gene coordinate index from Ensembl (GRCh38)
+# ---------------------------------------------------------------------------
+
+def fetch_gene_annotations() -> pd.DataFrame:
+ """
+ Retrieve gene annotations from Ensembl BioMart (GRCh38).
+ Keeps protein-coding genes and lncRNAs on standard chromosomes.
+ Returns a DataFrame with columns: chrom, start, end, strand, gene_name
+ """
+ log.info("Fetching gene annotations from Ensembl BioMart ...")
+ server = Server(host="http://www.ensembl.org")
+ dataset = server["ENSEMBL_MART_ENSEMBL"]["hsapiens_gene_ensembl"]
+
+ result = dataset.query(
+ attributes=[
+ "chromosome_name",
+ "start_position",
+ "end_position",
+ "strand",
+ "external_gene_name",
+ "gene_biotype",
+ ],
+ )
+
+ result.columns = ["chrom", "start", "end", "strand", "gene_name", "biotype"]
+
+ # Keep protein-coding genes and lncRNAs (commonly bound by RBPs)
+ keep_biotypes = {"protein_coding", "lncRNA"}
+ result = result[result["biotype"].isin(keep_biotypes)].copy()
+
+ # Only keep standard chromosomes (1-22, X, Y)
+ standard_chroms = {str(c) for c in range(1, 23)} | {"X", "Y"}
+ result = result[result["chrom"].isin(standard_chroms)].copy()
+
+ # Add 'chr' prefix to match ENCODE bed files
+ result["chrom"] = "chr" + result["chrom"].astype(str)
+
+ # Drop rows without gene names
+ result = result[result["gene_name"].notna() & (result["gene_name"] != "")].copy()
+ result = result.drop(columns=["biotype"]).reset_index(drop=True)
+
+ log.info(f" Retrieved {len(result):,} gene annotations")
+ return result
+
+
+def build_gene_index(genes_df: pd.DataFrame) -> dict:
+ """
+ Build a chromosome-indexed dict for fast overlap queries.
+ Returns: {chrom: list of (start, end, gene_name)} sorted by start.
+ """
+ index = defaultdict(list)
+ for _, row in genes_df.iterrows():
+ index[row["chrom"]].append(
+ (int(row["start"]), int(row["end"]), row["gene_name"])
+ )
+
+ # Sort each chromosome by start position
+ for chrom in index:
+ index[chrom].sort(key=lambda x: x[0])
+
+ return dict(index)
+
+
+def find_overlapping_genes(
+ chrom: str, peak_start: int, peak_end: int, gene_index: dict
+) -> set:
+ """
+ Find all genes whose genomic interval overlaps with a peak region.
+ Uses binary search on sorted gene starts for efficiency.
+ """
+ genes = gene_index.get(chrom, [])
+ if not genes:
+ return set()
+
+ starts = [g[0] for g in genes]
+ # Find the index of the first gene whose start >= peak_end
+ right_idx = bisect.bisect_left(starts, peak_end)
+
+ overlapping = set()
+
+ # Scan backwards from right_idx to find all genes overlapping the peak.
+ # A gene overlaps if gene_start < peak_end AND gene_end > peak_start.
+ # Since genes are sorted by start, once gene_start drops well below
+ # peak_start we use a distance cutoff to stop (genes can be long).
+ for i in range(max(0, right_idx - 1), -1, -1):
+ g_start, g_end, g_name = genes[i]
+ if g_start < peak_end and g_end > peak_start:
+ overlapping.add(g_name)
+ # Safety cutoff: stop if gene starts > 2 Mb before peak start
+ if g_start < peak_start - 2_000_000:
+ break
+
+ # Also check a few genes forward (edge cases at the boundary)
+ for i in range(right_idx, min(len(genes), right_idx + 10)):
+ g_start, g_end, g_name = genes[i]
+ if g_start >= peak_end:
+ break
+ if g_start < peak_end and g_end > peak_start:
+ overlapping.add(g_name)
+
+ return overlapping
+
+
+# ---------------------------------------------------------------------------
+# Step 2: Query ENCODE API for eCLIP experiments
+# ---------------------------------------------------------------------------
+
+def search_eclip_experiments(target_label: str) -> list[dict]:
+ """
+ Search ENCODE for eCLIP experiments targeting a given gene label (human).
+ Returns list of experiment info dicts.
+ """
+ url = f"{ENCODE_BASE}/search/"
+ params = {
+ "type": "Experiment",
+ "assay_title": "eCLIP",
+ "target.label": target_label,
+ "status": "released",
+ "format": "json",
+ "limit": "all",
+ }
+
+ try:
+ r = requests.get(url, params=params, headers=ENCODE_HEADERS, timeout=30)
+ r.raise_for_status()
+ except requests.RequestException as e:
+ log.warning(f" API search failed for {target_label}: {e}")
+ return []
+
+ data = r.json()
+ experiments = []
+ for exp in data.get("@graph", []):
+ experiments.append({
+ "accession": exp["accession"],
+ "biosample_summary": exp.get("biosample_summary", "unknown"),
+ "target_label": exp.get("target", {}).get("label", target_label),
+ })
+
+ return experiments
+
+
+def find_idr_peaks_file(experiment_accession: str) -> dict | None:
+ """
+ For an experiment, find the IDR-merged peaks file (GRCh38, bed narrowPeak).
+ The IDR-merged file has biological_replicates containing both rep1 and rep2.
+ Falls back to any released bed narrowPeak if IDR-merged not found.
+ """
+ url = (
+ f"{ENCODE_BASE}/experiments/{experiment_accession}/"
+ f"?format=json&frame=embedded"
+ )
+
+ try:
+ r = requests.get(url, headers=ENCODE_HEADERS, timeout=30)
+ r.raise_for_status()
+ except requests.RequestException as e:
+ log.warning(f" Failed to get experiment {experiment_accession}: {e}")
+ return None
+
+ exp_data = r.json()
+ files = exp_data.get("files", [])
+
+ # Find bed narrowPeak files that are released, preferring IDR-merged
+ # (biological_replicates has 2+ entries)
+ idr_candidates = []
+ single_rep_candidates = []
+
+ for f in files:
+ if not isinstance(f, dict):
+ continue
+ if (
+ f.get("output_type") == "peaks"
+ and f.get("file_format") == "bed"
+ and f.get("file_format_type") == "narrowPeak"
+ and f.get("status") == "released"
+ ):
+ if len(f.get("biological_replicates", [])) >= 2:
+ idr_candidates.append(f)
+ else:
+ single_rep_candidates.append(f)
+
+ candidates = idr_candidates if idr_candidates else single_rep_candidates
+ if not candidates:
+ return None
+
+ # Prefer GRCh38 assembly
+ for f in candidates:
+ if f.get("assembly") == "GRCh38":
+ return {
+ "accession": f.get("accession"),
+ "href": f.get("href"),
+ "assembly": f.get("assembly"),
+ "biological_replicates": f.get("biological_replicates"),
+ }
+
+ # Fall back to any assembly
+ f = candidates[0]
+ return {
+ "accession": f.get("accession"),
+ "href": f.get("href"),
+ "assembly": f.get("assembly"),
+ "biological_replicates": f.get("biological_replicates"),
+ }
+
+
+# ---------------------------------------------------------------------------
+# Step 3: Download and parse peak files
+# ---------------------------------------------------------------------------
+
+def download_and_parse_peaks(href: str) -> list[tuple]:
+ """
+ Download a bed.gz file from ENCODE and parse it.
+ Returns list of (chrom, start, end) tuples.
+ """
+ url = ENCODE_BASE + href
+
+ try:
+ r = requests.get(url, timeout=120)
+ r.raise_for_status()
+ except requests.RequestException as e:
+ log.warning(f" Failed to download {url}: {e}")
+ return []
+
+ content = r.content
+ try:
+ text = gzip.decompress(content).decode("utf-8", errors="replace")
+ except gzip.BadGzipFile:
+ text = content.decode("utf-8", errors="replace")
+
+ peaks = []
+ for line in text.strip().split("\n"):
+ if not line or line.startswith("#") or line.startswith("track"):
+ continue
+ fields = line.split("\t")
+ if len(fields) < 3:
+ continue
+ chrom = fields[0]
+ try:
+ start = int(fields[1])
+ end = int(fields[2])
+ except ValueError:
+ continue
+ peaks.append((chrom, start, end))
+
+ return peaks
+
+
+# ---------------------------------------------------------------------------
+# Step 4: Map peaks to genes
+# ---------------------------------------------------------------------------
+
+def map_peaks_to_genes(peaks: list[tuple], gene_index: dict) -> set:
+ """Map a list of peaks to overlapping gene names."""
+ all_genes = set()
+ for chrom, start, end in peaks:
+ genes = find_overlapping_genes(chrom, start, end, gene_index)
+ all_genes.update(genes)
+ return all_genes
+
+
+# ---------------------------------------------------------------------------
+# Main
+# ---------------------------------------------------------------------------
+
+def main():
+ # Step 1: Get gene annotations
+ genes_df = fetch_gene_annotations()
+ gene_index = build_gene_index(genes_df)
+ log.info(f"Gene index built for {len(gene_index)} chromosomes")
+
+ # Step 2-4: For each RBP, query ENCODE, download peaks, map to genes
+ all_results = [] # list of (rbp, target_gene) tuples
+ rbps_found = []
+ rbps_not_found = []
+
+ for rbp in RBPS:
+ encode_label = ENCODE_LABEL.get(rbp, rbp)
+ if encode_label is None:
+ log.warning(f"Skipping {rbp} -- no ENCODE eCLIP data available")
+ rbps_not_found.append(rbp)
+ continue
+
+ note = ENCODE_LABEL_NOTE.get(rbp, "")
+ if note:
+ log.info(f"Processing {rbp} (using {note}) ...")
+ else:
+ log.info(f"Processing {rbp} ...")
+
+ time.sleep(REQUEST_DELAY)
+
+ # Search for experiments
+ experiments = search_eclip_experiments(encode_label)
+ if not experiments:
+ log.warning(f" No eCLIP experiments found for {encode_label}")
+ rbps_not_found.append(rbp)
+ continue
+
+ log.info(f" Found {len(experiments)} experiment(s)")
+
+ rbp_targets = set()
+
+ for exp in experiments:
+ acc = exp["accession"]
+ biosample = exp["biosample_summary"]
+ log.info(f" Experiment {acc} ({biosample})")
+ time.sleep(REQUEST_DELAY)
+
+ # Find IDR peaks file
+ peaks_file = find_idr_peaks_file(acc)
+ if not peaks_file:
+ log.warning(f" No peaks file found for {acc}")
+ continue
+
+ log.info(
+ f" Peaks file: {peaks_file['accession']} "
+ f"(assembly={peaks_file['assembly']}, "
+ f"bio_reps={peaks_file['biological_replicates']})"
+ )
+ time.sleep(REQUEST_DELAY)
+
+ # Download and parse peaks
+ peaks = download_and_parse_peaks(peaks_file["href"])
+ if not peaks:
+ log.warning(
+ f" No peaks parsed from {peaks_file['accession']}"
+ )
+ continue
+
+ log.info(f" Downloaded {len(peaks):,} peaks")
+
+ # Map peaks to genes
+ target_genes = map_peaks_to_genes(peaks, gene_index)
+ log.info(f" Mapped to {len(target_genes):,} unique target genes")
+
+ rbp_targets.update(target_genes)
+
+ if rbp_targets:
+ rbps_found.append(rbp)
+ for gene in sorted(rbp_targets):
+ all_results.append((rbp, gene))
+ log.info(
+ f" Total unique targets for {rbp}: {len(rbp_targets):,}"
+ )
+ else:
+ rbps_not_found.append(rbp)
+ log.warning(f" No targets found for {rbp}")
+
+ # Step 5: Save results
+ if all_results:
+ df = pd.DataFrame(all_results, columns=["rbp", "target_gene"])
+ os.makedirs(os.path.dirname(OUTPUT_CSV), exist_ok=True)
+ df.to_csv(OUTPUT_CSV, index=False)
+ log.info(f"\nSaved {len(df):,} RBP-target pairs to {OUTPUT_CSV}")
+ log.info(f"RBPs with data: {sorted(rbps_found)}")
+ log.info(f"RBPs without data: {sorted(rbps_not_found)}")
+ log.info("\nSummary per RBP:")
+ for rbp, group in df.groupby("rbp"):
+ note = ENCODE_LABEL_NOTE.get(rbp, "")
+ suffix = f" ({note})" if note else ""
+ log.info(f" {rbp}: {len(group):,} target genes{suffix}")
+ else:
+ log.error("No results found for any RBP!")
+ sys.exit(1)
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_all.py b/analyses/run_all.py
new file mode 100644
index 0000000000000000000000000000000000000000..354a7fc318c9366c1adc2994cf65d221bcc36baa
--- /dev/null
+++ b/analyses/run_all.py
@@ -0,0 +1,302 @@
+#!/usr/bin/env python
+"""Run the full scPTR analysis pipeline on pancreas data and produce results.
+
+This script runs Aims 1-3 end-to-end on the pancreas dataset:
+- Aim 1: Benchmark gamma estimates against published half-lives, ARE/NMD enrichment
+- Aim 2: PT state discovery and differential gamma analysis
+- Aim 3: PT velocity computation
+
+Results are saved to output/ directory.
+"""
+
+from __future__ import annotations
+
+import json
+import sys
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+
+# Add project root to path
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style, setup_output_dirs
+
+import scptr
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output"
+
+
+def save_fig(fig, name, subdir="figures"):
+ """Save a matplotlib figure to output dir."""
+ if fig is None:
+ print(f" [WARNING] {name}: plot returned None, skipping save")
+ return
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+def main():
+ set_figure_style()
+ OUTPUT_DIR.mkdir(exist_ok=True)
+
+ # =========================================================================
+ # LOAD DATA
+ # =========================================================================
+ print("=" * 60)
+ print("LOADING PANCREAS DATASET")
+ print("=" * 60)
+ adata = scptr.datasets.pancreas()
+ print(f" Shape: {adata.shape}")
+ print(f" Layers: {list(adata.layers.keys())}")
+ print(f" Cell types: {adata.obs['clusters'].value_counts().to_dict()}")
+
+ # =========================================================================
+ # PREPROCESSING
+ # =========================================================================
+ print("\n" + "=" * 60)
+ print("PREPROCESSING")
+ print("=" * 60)
+
+ scptr.pp.filter_genes(adata)
+ print(f" After filtering: {adata.shape}")
+
+ scptr.pp.normalize_layers(adata)
+ print(" Normalized layers")
+
+ scptr.pp.neighbors(adata, n_neighbors=30)
+ print(" Built kNN graph (k=30)")
+
+ scptr.pp.smooth_layers(adata)
+ print(" Smoothed layers (Mu, Ms)")
+
+ # =========================================================================
+ # CORE ANALYSIS
+ # =========================================================================
+ print("\n" + "=" * 60)
+ print("CORE ANALYSIS")
+ print("=" * 60)
+
+ # Beta estimation (global + per-cell-type)
+ scptr.tl.estimate_beta(adata)
+ beta = adata.var['beta'].values
+ print(f" Beta: median={np.median(beta):.4f}, max={np.max(beta):.4f}, "
+ f"nonzero={np.sum(beta > 0)}/{len(beta)}")
+
+ if "clusters" in adata.obs.columns:
+ scptr.tl.estimate_beta(adata, groupby="clusters")
+ print(f" Beta (per-cluster): {adata.varm['beta_groups'].shape}")
+
+ # Gamma estimation
+ scptr.tl.estimate_gamma(adata)
+ gamma_vals = adata.layers["gamma"]
+ gamma_med = np.median(gamma_vals, axis=0)
+ print(f" Gamma: shape={gamma_vals.shape}")
+ print(f" Median per-gene: median={np.median(gamma_med):.4f}, "
+ f"max={np.max(gamma_med):.4f}")
+ print(f" Global: max={np.max(gamma_vals):.4f}, "
+ f"99.5th pctl={np.percentile(gamma_vals[gamma_vals>0], 99.5):.4f}")
+ print(f" Genes with >0 median gamma: {np.sum(gamma_med > 0)}/{len(gamma_med)}")
+
+ # Variance decomposition
+ scptr.tl.variance_decomposition(adata)
+ tf = adata.var['tf_score'].values
+ ptf = adata.var['ptf_score'].values
+ print(f" TF score: median={np.median(tf):.4f}, mean={np.mean(tf):.4f}")
+ print(f" PTF score: median={np.median(ptf):.4f}, mean={np.mean(ptf):.4f}")
+ print(f" Genes with TF > 0.5: {np.sum(tf > 0.5)}/{len(tf)}")
+
+ # PT states
+ scptr.tl.pt_states(adata)
+ n_states = adata.obs["pt_state"].nunique()
+ print(f" PT states found: {n_states}")
+
+ # PT velocity
+ scptr.tl.pt_velocity(adata)
+ print(" PT velocity computed")
+
+ # =========================================================================
+ # AIM 1: BENCHMARKING
+ # =========================================================================
+ print("\n" + "=" * 60)
+ print("AIM 1: BENCHMARKING")
+ print("=" * 60)
+ fig_dir, res_dir = setup_output_dirs("figures/aim1", "results/aim1")
+
+ # 1a. Half-life correlation (mouse reference)
+ print("\n--- Half-life correlation (mouse reference) ---")
+ hl_mouse = scptr.datasets.herzog2017_halflives()
+ corr = scptr.benchmark.correlate_with_halflives(adata, hl_mouse)
+ print(f" n_genes matched: {corr['n_genes']} (unfiltered: {corr['n_genes_unfiltered']})")
+ print(f" Spearman r = {corr['spearman_r']:.4f} (p = {corr['spearman_p']:.2e})")
+ print(f" Pearson r = {corr['pearson_r']:.4f} (p = {corr['pearson_p']:.2e})")
+
+ # Also try human reference for cross-species comparison
+ print("\n--- Half-life correlation (human reference) ---")
+ hl_human = scptr.datasets.schofield2018_halflives()
+ corr_human = scptr.benchmark.correlate_with_halflives(adata, hl_human)
+ print(f" n_genes matched: {corr_human['n_genes']} (unfiltered: {corr_human['n_genes_unfiltered']})")
+ print(f" Spearman r = {corr_human['spearman_r']:.4f} (p = {corr_human['spearman_p']:.2e})")
+
+ # Save both correlation results
+ corr_save = {k: v for k, v in corr.items() if k != "matched_genes"}
+ corr_human_save = {k: v for k, v in corr_human.items() if k != "matched_genes"}
+ with open(res_dir / "halflife_correlation.json", "w") as f:
+ json.dump({"mouse_reference": corr_save, "human_reference": corr_human_save}, f, indent=2)
+
+ # Half-life scatter plot (log-log scale, filtered genes only)
+ fig, axes = plt.subplots(1, 2, figsize=(13, 5))
+
+ gamma_med = np.median(adata.layers["gamma"], axis=0)
+ gamma_s = pd.Series(gamma_med, index=adata.var_names)
+ hl_s = hl_mouse.set_index("gene_symbol")["half_life_hours"]
+ shared = gamma_s.index.intersection(hl_s.index)
+ g = gamma_s[shared].values
+ h = hl_s[shared].values
+
+ # Left: all genes
+ axes[0].scatter(h, g, alpha=0.1, s=5, c="steelblue")
+ axes[0].set_xlabel("Published half-life (hours)")
+ axes[0].set_ylabel("scPTR median gamma")
+ axes[0].set_title(f"All genes (n={len(shared)})")
+
+ # Right: filtered genes (gamma > 0), log-log
+ mask = (g > 0) & (h > 0) & np.isfinite(g) & np.isfinite(h)
+ axes[1].scatter(h[mask], g[mask], alpha=0.15, s=8, c="steelblue")
+ axes[1].set_xscale("log")
+ axes[1].set_yscale("log")
+ axes[1].set_xlabel("Published half-life (hours)")
+ axes[1].set_ylabel("scPTR median gamma")
+ axes[1].set_title(
+ f"Filtered genes (Spearman r={corr['spearman_r']:.3f}, "
+ f"p={corr['spearman_p']:.1e}, n={corr['n_genes']})"
+ )
+ fig.suptitle("Gamma vs Published mRNA Half-lives", fontsize=13, y=1.02)
+ fig.tight_layout()
+ save_fig(fig, "halflife_scatter", "figures/aim1")
+
+ # 1b. ARE / NMD enrichment
+ print("\n--- ARE / NMD enrichment ---")
+ are_result = scptr.benchmark.are_enrichment(adata)
+ nmd_result = scptr.benchmark.nmd_enrichment(adata)
+ print(f" ARE: n_in={are_result['n_genes_in_set']}, "
+ f"median_gamma_in={are_result.get('median_gamma_in_set', 'N/A'):.4f}, "
+ f"median_gamma_bg={are_result.get('median_gamma_background', 'N/A'):.4f}, "
+ f"p={are_result['p_value']:.4f}")
+ print(f" NMD: n_in={nmd_result['n_genes_in_set']}, "
+ f"median_gamma_in={nmd_result.get('median_gamma_in_set', 'N/A'):.4f}, "
+ f"median_gamma_bg={nmd_result.get('median_gamma_background', 'N/A'):.4f}, "
+ f"p={nmd_result['p_value']:.4f}")
+
+ with open(res_dir / "enrichment_results.json", "w") as f:
+ json.dump({"ARE": are_result, "NMD": nmd_result}, f, indent=2)
+
+ fig = scptr.pl.enrichment_barplot([are_result, nmd_result])
+ save_fig(fig, "enrichment_barplot", "figures/aim1")
+
+ # 1c. Subsampling robustness
+ print("\n--- Subsampling robustness ---")
+ fractions = [0.2, 0.4, 0.6, 0.8, 0.9]
+ robust_df = scptr.benchmark.subsampling_robustness(
+ adata, fractions=fractions, n_repeats=5
+ )
+ robust_df.to_csv(res_dir / "subsampling_robustness.csv", index=False)
+
+ for frac in fractions:
+ sub = robust_df[robust_df["fraction"] == frac]
+ mean_r = sub["spearman_r"].mean()
+ print(f" fraction={frac:.1f}: mean Spearman r = {mean_r:.4f}")
+
+ # Robustness plot
+ fig, ax = plt.subplots(figsize=(6, 4))
+ for frac in fractions:
+ sub = robust_df[robust_df["fraction"] == frac]
+ ax.scatter([frac] * len(sub), sub["spearman_r"],
+ color="steelblue", alpha=0.6, s=25)
+ means = robust_df.groupby("fraction")["spearman_r"].mean()
+ ax.plot(means.index, means.values, "o-", color="darkblue", linewidth=2, markersize=6)
+ ax.set_xlabel("Fraction of cells")
+ ax.set_ylabel("Spearman r (vs full data)")
+ ax.set_title("Subsampling Robustness")
+ ax.set_ylim(0.5, 1.02)
+ save_fig(fig, "subsampling_robustness", "figures/aim1")
+
+ # =========================================================================
+ # AIM 2: HIDDEN PT STATES
+ # =========================================================================
+ print("\n" + "=" * 60)
+ print("AIM 2: PT STATE DISCOVERY")
+ print("=" * 60)
+ fig_dir, res_dir = setup_output_dirs("figures/aim2", "results/aim2")
+
+ # State composition
+ state_counts = adata.obs["pt_state"].value_counts()
+ state_counts.to_csv(res_dir / "pt_state_counts.csv")
+ print(f" PT states: {dict(state_counts)}")
+
+ # PT UMAP (use show=False to get fig back)
+ fig = scptr.pl.pt_umap(adata, show=False)
+ save_fig(fig, "pt_umap", "figures/aim2")
+
+ # TF vs PTF scatter
+ fig = scptr.pl.tf_ptf_scatter(adata, show=False)
+ save_fig(fig, "tf_ptf_scatter", "figures/aim2")
+
+ # Cross-tabulate PT states vs expression clusters
+ if "clusters" in adata.obs.columns:
+ ct = pd.crosstab(adata.obs["pt_state"], adata.obs["clusters"])
+ ct.to_csv(res_dir / "pt_state_vs_clusters.csv")
+ print(f"\n PT state vs expression cluster crosstab:")
+ print(ct.to_string())
+
+ # Rank genes by differential gamma
+ rank_df = scptr.tl.rank_pt_genes(adata, n_genes=50)
+ rank_df.to_csv(res_dir / "ranked_pt_genes.csv", index=False)
+ print(f"\n Top differentially degraded genes: {len(rank_df)} entries")
+ print(f" Top 10 gene names: {rank_df.head(10)['names'].tolist()}")
+
+ # Gamma heatmap
+ fig = scptr.pl.gamma_heatmap(adata, show=False)
+ save_fig(fig, "gamma_heatmap", "figures/aim2")
+
+ # =========================================================================
+ # AIM 3: PT VELOCITY
+ # =========================================================================
+ print("\n" + "=" * 60)
+ print("AIM 3: PT VELOCITY")
+ print("=" * 60)
+ fig_dir, res_dir = setup_output_dirs("figures/aim3", "results/aim3")
+
+ # Velocity embedding (show 30% of cells for cleaner arrows)
+ fig = scptr.pl.pt_velocity_embedding(adata, density=0.3, arrow_size=1.5, show=False)
+ save_fig(fig, "pt_velocity_embedding", "figures/aim3")
+
+ # =========================================================================
+ # SUMMARY
+ # =========================================================================
+ print("\n" + "=" * 60)
+ print("SUMMARY")
+ print("=" * 60)
+ print(f" Dataset: pancreas ({adata.n_obs} cells, {adata.n_vars} genes)")
+ print(f" Beta: median={np.median(adata.var['beta']):.4f}, max={np.max(adata.var['beta']):.4f}")
+ print(f" Gamma max: {np.max(adata.layers['gamma']):.4f}")
+ print(f" PT states discovered: {n_states}")
+ print(f" TF score: median={np.median(adata.var['tf_score']):.4f}")
+ print(f" Half-life Spearman r (mouse): {corr['spearman_r']:.4f} (n={corr['n_genes']} genes)")
+ print(f" Half-life Spearman r (human): {corr_human['spearman_r']:.4f} (n={corr_human['n_genes']} genes)")
+ print(f" ARE enrichment p: {are_result['p_value']:.4f}")
+ print(f" NMD enrichment p: {nmd_result['p_value']:.4f}")
+ print(f" Robustness (90% cells): {robust_df[robust_df['fraction']==0.9]['spearman_r'].mean():.4f}")
+ print(f"\nAll results saved to: {OUTPUT_DIR.resolve()}")
+ print("Done!")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_cross_platform.py b/analyses/run_cross_platform.py
new file mode 100644
index 0000000000000000000000000000000000000000..34763e91bd28be266eef7589a49b529adc5e2346
--- /dev/null
+++ b/analyses/run_cross_platform.py
@@ -0,0 +1,278 @@
+#!/usr/bin/env python
+"""Cross-platform benchmarking: compare scPTR gamma estimates across
+different sequencing platforms and datasets.
+
+Compares gamma estimates between:
+1. 10x Chromium datasets (pancreas, dentate gyrus)
+2. sci (combinatorial indexing) dataset (sci-fate A549)
+3. Assesses whether gene-level gamma rankings are consistent across platforms
+
+This addresses the cross-platform benchmarking component of the research plan.
+"""
+
+from __future__ import annotations
+
+import json
+import sys
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+from scipy import stats
+
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style
+
+import scptr
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output" / "cross_platform"
+
+
+def save_fig(fig, name, subdir="figures"):
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+def run_pipeline(adata, name):
+ """Run full scPTR pipeline and return per-gene median gamma."""
+ import copy
+ adata = copy.deepcopy(adata)
+ scptr.pp.filter_genes(adata)
+ scptr.pp.normalize_layers(adata)
+ scptr.pp.neighbors(adata, n_neighbors=30)
+ scptr.pp.smooth_layers(adata)
+ scptr.tl.estimate_beta(adata)
+ scptr.tl.estimate_gamma(adata)
+
+ gamma = np.median(adata.layers["gamma"], axis=0)
+ expr = np.mean(adata.layers["spliced"], axis=0) if "spliced" in adata.layers else np.mean(adata.X, axis=0)
+ if hasattr(expr, 'A1'):
+ expr = np.asarray(expr).flatten()
+
+ return pd.DataFrame({
+ "gene": adata.var_names,
+ "gamma": gamma,
+ "expression": expr,
+ "nonzero_frac": (adata.layers["gamma"] > 0).mean(axis=0),
+ }).set_index("gene"), adata
+
+
+def compare_datasets(df_a, df_b, name_a, name_b):
+ """Compare gamma estimates between two datasets."""
+ print(f"\n {name_a} vs {name_b}:")
+
+ # Find shared genes (case-insensitive)
+ genes_a = {g.upper(): g for g in df_a.index}
+ genes_b = {g.upper(): g for g in df_b.index}
+ shared = set(genes_a.keys()) & set(genes_b.keys())
+ print(f" Shared genes: {len(shared)}")
+
+ if len(shared) < 50:
+ print(f" Too few shared genes for comparison.")
+ return None
+
+ gamma_a = np.array([df_a.loc[genes_a[g], "gamma"] for g in shared])
+ gamma_b = np.array([df_b.loc[genes_b[g], "gamma"] for g in shared])
+ expr_a = np.array([df_a.loc[genes_a[g], "expression"] for g in shared])
+ expr_b = np.array([df_b.loc[genes_b[g], "expression"] for g in shared])
+ nonzero_a = np.array([df_a.loc[genes_a[g], "nonzero_frac"] for g in shared])
+ nonzero_b = np.array([df_b.loc[genes_b[g], "nonzero_frac"] for g in shared])
+
+ # Overall correlation
+ valid = (gamma_a > 0) & (gamma_b > 0)
+ if valid.sum() < 20:
+ print(f" Too few valid genes (both gamma>0): {valid.sum()}")
+ return None
+
+ r_gamma, p_gamma = stats.spearmanr(gamma_a[valid], gamma_b[valid])
+ r_expr, p_expr = stats.spearmanr(expr_a[valid], expr_b[valid])
+
+ print(f" Gamma Spearman r = {r_gamma:.4f} (n={valid.sum()})")
+ print(f" Expression Spearman r = {r_expr:.4f}")
+
+ # Stratify by expression level
+ expr_combined = expr_a + expr_b
+ quartiles = np.percentile(expr_combined[valid], [25, 50, 75])
+ labels = ["Q1 (low)", "Q2", "Q3", "Q4 (high)"]
+ bounds = [(-np.inf, quartiles[0]), (quartiles[0], quartiles[1]),
+ (quartiles[1], quartiles[2]), (quartiles[2], np.inf)]
+
+ print(f"\n Stratified by expression level:")
+ stratified = []
+ for label, (lo, hi) in zip(labels, bounds):
+ mask = valid & (expr_combined >= lo) & (expr_combined < hi)
+ if mask.sum() < 10:
+ continue
+ r_q, p_q = stats.spearmanr(gamma_a[mask], gamma_b[mask])
+ r_e, _ = stats.spearmanr(expr_a[mask], expr_b[mask])
+ print(f" {label}: gamma r={r_q:.3f}, expr r={r_e:.3f} (n={mask.sum()})")
+ stratified.append({
+ "quartile": label,
+ "gamma_r": float(r_q),
+ "expr_r": float(r_e),
+ "n_genes": int(mask.sum()),
+ })
+
+ # Informative genes only (>10% nonzero in both)
+ informative = valid & (nonzero_a >= 0.1) & (nonzero_b >= 0.1)
+ if informative.sum() >= 20:
+ r_inf, _ = stats.spearmanr(gamma_a[informative], gamma_b[informative])
+ print(f"\n Informative genes only (>10% nonzero both): "
+ f"r={r_inf:.4f} (n={informative.sum()})")
+
+ return {
+ "dataset_a": name_a,
+ "dataset_b": name_b,
+ "shared_genes": len(shared),
+ "valid_genes": int(valid.sum()),
+ "gamma_r": float(r_gamma),
+ "expr_r": float(r_expr),
+ "informative_gamma_r": float(r_inf) if informative.sum() >= 20 else None,
+ "stratified": stratified,
+ }
+
+
+def main():
+ set_figure_style()
+ OUTPUT_DIR.mkdir(parents=True, exist_ok=True)
+
+ # Load datasets
+ print("=" * 60)
+ print("CROSS-PLATFORM BENCHMARKING")
+ print("=" * 60)
+
+ datasets = {}
+
+ # 10x Chromium datasets
+ print("\nLoading pancreas (10x Chromium)...")
+ df_pan, adata_pan = run_pipeline(scptr.datasets.pancreas(), "pancreas")
+ datasets["pancreas_10x"] = df_pan
+ print(f" {len(df_pan)} genes, {(df_pan['gamma'] > 0).sum()} with gamma>0")
+
+ print("\nLoading dentate gyrus (10x Chromium)...")
+ df_dg, adata_dg = run_pipeline(scptr.datasets.dentate_gyrus(), "dentate_gyrus")
+ datasets["dg_10x"] = df_dg
+ print(f" {len(df_dg)} genes, {(df_dg['gamma'] > 0).sum()} with gamma>0")
+
+ # sci-fate (combinatorial indexing)
+ try:
+ print("\nLoading sci-fate (sci)...")
+ df_sci, adata_sci = run_pipeline(scptr.datasets.sci_fate(), "sci_fate")
+ datasets["scifate_sci"] = df_sci
+ print(f" {len(df_sci)} genes, {(df_sci['gamma'] > 0).sum()} with gamma>0")
+ except Exception as e:
+ print(f" sci-fate not available: {e}")
+
+ # Pairwise comparisons
+ print("\n" + "=" * 60)
+ print("PAIRWISE COMPARISONS")
+ print("=" * 60)
+
+ pairs = []
+ dataset_names = list(datasets.keys())
+ all_comparisons = []
+
+ for i in range(len(dataset_names)):
+ for j in range(i + 1, len(dataset_names)):
+ name_a, name_b = dataset_names[i], dataset_names[j]
+ result = compare_datasets(datasets[name_a], datasets[name_b],
+ name_a, name_b)
+ if result:
+ all_comparisons.append(result)
+
+ # Platform comparison summary
+ print(f"\n{'='*60}")
+ print("PLATFORM COMPARISON SUMMARY")
+ print(f"{'='*60}")
+
+ # Categorize comparisons
+ same_platform = []
+ cross_platform = []
+ for comp in all_comparisons:
+ a, b = comp["dataset_a"], comp["dataset_b"]
+ a_platform = "10x" if "10x" in a else "sci" if "sci" in a else "other"
+ b_platform = "10x" if "10x" in b else "sci" if "sci" in b else "other"
+
+ if a_platform == b_platform:
+ same_platform.append(comp)
+ else:
+ cross_platform.append(comp)
+
+ print(f"\n Same platform comparisons:")
+ for comp in same_platform:
+ print(f" {comp['dataset_a']} vs {comp['dataset_b']}: "
+ f"gamma r={comp['gamma_r']:.3f}")
+
+ print(f"\n Cross-platform comparisons:")
+ for comp in cross_platform:
+ print(f" {comp['dataset_a']} vs {comp['dataset_b']}: "
+ f"gamma r={comp['gamma_r']:.3f}")
+
+ # Half-life validation per platform
+ print(f"\n Half-life validation per platform:")
+ halflife_dir = Path(__file__).parent.parent / "src" / "scptr" / "datasets" / "data"
+ for hl_file, hl_name in [("schofield2018_halflives.csv", "Schofield 2018")]:
+ hl_path = halflife_dir / hl_file
+ if not hl_path.exists():
+ continue
+
+ hl = pd.read_csv(hl_path)
+ for ds_name, df in datasets.items():
+ gene_map = {g.upper(): g for g in df.index}
+ gamma_vals, hl_vals = [], []
+ for _, row in hl.iterrows():
+ g = str(row.iloc[0]).upper()
+ if g in gene_map and df.loc[gene_map[g], "gamma"] > 0:
+ gamma_vals.append(df.loc[gene_map[g], "gamma"])
+ hl_vals.append(float(row.iloc[1]))
+ if len(gamma_vals) >= 20:
+ r, p = stats.spearmanr(gamma_vals, hl_vals)
+ print(f" {ds_name}: r={r:.4f}, n={len(gamma_vals)} ({hl_name})")
+
+ # Save results
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+ with open(res_dir / "cross_platform_results.json", "w") as f:
+ json.dump(all_comparisons, f, indent=2)
+
+ # Figure
+ n_comps = len(all_comparisons)
+ fig, axes = plt.subplots(1, max(n_comps, 1), figsize=(6 * max(n_comps, 1), 5))
+ if n_comps == 1:
+ axes = [axes]
+
+ for idx, comp in enumerate(all_comparisons):
+ name_a, name_b = comp["dataset_a"], comp["dataset_b"]
+ df_a, df_b = datasets[name_a], datasets[name_b]
+
+ genes_a = {g.upper(): g for g in df_a.index}
+ genes_b = {g.upper(): g for g in df_b.index}
+ shared = set(genes_a.keys()) & set(genes_b.keys())
+
+ ga = np.array([df_a.loc[genes_a[g], "gamma"] for g in shared])
+ gb = np.array([df_b.loc[genes_b[g], "gamma"] for g in shared])
+ valid = (ga > 0) & (gb > 0)
+
+ axes[idx].scatter(ga[valid], gb[valid], s=2, alpha=0.3, color="steelblue")
+ axes[idx].set_xlabel(f"Gamma ({name_a})")
+ axes[idx].set_ylabel(f"Gamma ({name_b})")
+ axes[idx].set_title(f"r={comp['gamma_r']:.3f} (n={comp['valid_genes']})")
+ lim = max(ga[valid].max(), gb[valid].max()) * 1.1
+ axes[idx].plot([0, lim], [0, lim], "r--", alpha=0.5)
+
+ fig.suptitle("Cross-Platform Gamma Comparison", fontsize=13, y=1.02)
+ fig.tight_layout()
+ save_fig(fig, "cross_platform_gamma")
+
+ print(f"\nResults saved to: {OUTPUT_DIR.resolve()}")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_deep_advantages.py b/analyses/run_deep_advantages.py
new file mode 100644
index 0000000000000000000000000000000000000000..c2dae56b1293a9ed7391084ac846fc07f84c3721
--- /dev/null
+++ b/analyses/run_deep_advantages.py
@@ -0,0 +1,784 @@
+#!/usr/bin/env python
+"""Demonstrate what DeepPTR can do that the analytical method cannot.
+
+Key advantages:
+1. Uncertainty-guided gene filtering improves half-life correlation
+2. Cell-specific gamma resolves transition-state heterogeneity
+3. Latent disentanglement discovers post-transcriptional programs
+4. Posterior sampling enables statistical testing of gamma differences
+
+All results saved to output/deep_advantages/.
+"""
+
+from __future__ import annotations
+
+import os
+os.environ["OMP_NUM_THREADS"] = "4"
+os.environ["MKL_NUM_THREADS"] = "4"
+os.environ["OPENBLAS_NUM_THREADS"] = "4"
+os.environ["NUMEXPR_NUM_THREADS"] = "4"
+
+import json
+import sys
+import time
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+from scipy import stats
+import scanpy as sc
+
+import torch
+torch.set_num_threads(4)
+
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style
+
+import scptr
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output" / "deep_advantages"
+
+
+def save_fig(fig, name, subdir="figures"):
+ if fig is None:
+ return
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+def ensure_dirs():
+ for sub in ("figures", "results"):
+ (OUTPUT_DIR / sub).mkdir(parents=True, exist_ok=True)
+
+
+def select_top_genes(adata, n_top=300):
+ from scipy.sparse import issparse
+ u = adata.layers["unspliced"]
+ if issparse(u):
+ u = np.asarray(u.todense())
+ u = np.asarray(u, dtype=np.float32)
+ score = u.sum(axis=0) * (u > 0).mean(axis=0)
+ top_idx = np.sort(np.argsort(score)[::-1][:n_top])
+ adata_sub = adata[:, adata.var_names[top_idx]].copy()
+ from scipy.sparse import issparse as _iss
+ for key in ("spliced", "unspliced"):
+ if key in adata_sub.layers and _iss(adata_sub.layers[key]):
+ adata_sub.layers[key] = np.asarray(adata_sub.layers[key].todense())
+ return adata_sub
+
+
+def prepare_both(adata_loader, n_top=300):
+ """Run analytical and DeepPTR pipelines, return both adatas."""
+ # Analytical
+ adata_an = adata_loader()
+ scptr.pp.filter_genes(adata_an)
+ scptr.pp.normalize_layers(adata_an)
+ scptr.pp.neighbors(adata_an, n_neighbors=30)
+ scptr.pp.smooth_layers(adata_an)
+ scptr.tl.estimate_beta(adata_an)
+ scptr.tl.estimate_gamma(adata_an)
+
+ # DeepPTR
+ adata_dp = adata_loader()
+ scptr.pp.filter_genes(adata_dp)
+ scptr.pp.normalize_layers(adata_dp)
+ scptr.pp.neighbors(adata_dp, n_neighbors=30)
+ scptr.pp.smooth_layers(adata_dp)
+ scptr.tl.estimate_beta(adata_dp)
+ adata_dp = select_top_genes(adata_dp, n_top=n_top)
+
+ torch.set_num_threads(4)
+ model, history = scptr.deep.fit_deepptr(
+ adata_dp,
+ d_T=8, d_PT=8, d_hidden=48, n_enc_layers=2,
+ batch_size=512, max_epochs=100, kl_warmup_epochs=20,
+ patience=15, n_posterior_samples=30,
+ device="cpu", seed=0, verbose=True,
+ )
+ return adata_an, adata_dp, model
+
+
+# ============================================================================
+# 1. UNCERTAINTY-GUIDED GENE FILTERING
+# ============================================================================
+
+def advantage_uncertainty_filtering(adata_dp, dataset_name):
+ """Show that filtering genes by low posterior variance improves half-life correlation.
+
+ The analytical method has no uncertainty estimate — all genes are treated equally.
+ DeepPTR's posterior variance lets us select high-confidence genes, improving
+ downstream correlations.
+ """
+ print(f"\n{'=' * 60}")
+ print(f"ADVANTAGE 1: Uncertainty-guided gene filtering ({dataset_name})")
+ print("=" * 60)
+
+ hl_mouse = scptr.datasets.herzog2017_halflives()
+ hl_human = scptr.datasets.schofield2018_halflives()
+
+ gamma_med = np.median(adata_dp.layers["gamma"], axis=0)
+ gamma_var_med = np.median(adata_dp.layers["gamma_var"], axis=0)
+
+ # Coefficient of variation of gamma across posterior samples
+ gamma_cv = np.sqrt(gamma_var_med) / (gamma_med + 1e-8)
+
+ results = {}
+ for ref_name, hl_df in [("mouse", hl_mouse), ("human", hl_human)]:
+ # Match genes
+ hl_s = hl_df.set_index("gene_symbol")["half_life_hours"]
+ # Case-insensitive matching
+ gamma_upper = {g.upper(): i for i, g in enumerate(adata_dp.var_names)}
+ hl_upper = {g.upper(): g for g in hl_s.index if isinstance(g, str)}
+ shared = set(gamma_upper.keys()) & set(hl_upper.keys())
+
+ if len(shared) < 10:
+ print(f" {ref_name}: too few shared genes ({len(shared)})")
+ continue
+
+ g_idx = [gamma_upper[u] for u in shared]
+ h_vals = np.array([hl_s[hl_upper[u]] for u in shared], dtype=float)
+ g_vals = gamma_med[g_idx]
+ cv_vals = gamma_cv[g_idx]
+
+ valid = np.isfinite(g_vals) & np.isfinite(h_vals) & (g_vals > 0) & (h_vals > 0)
+ g_vals, h_vals, cv_vals = g_vals[valid], h_vals[valid], cv_vals[valid]
+
+ # Baseline: all genes
+ sp_all, _ = stats.spearmanr(g_vals, h_vals)
+
+ # Filter by uncertainty thresholds
+ thresholds = [1.0, 0.75, 0.5, 0.3, 0.2]
+ records = [{"threshold": "all", "n_genes": len(g_vals), "spearman_r": float(sp_all)}]
+
+ for thr in thresholds:
+ mask = cv_vals < thr
+ if mask.sum() < 10:
+ continue
+ sp_r, _ = stats.spearmanr(g_vals[mask], h_vals[mask])
+ records.append({
+ "threshold": f"CV<{thr}",
+ "n_genes": int(mask.sum()),
+ "spearman_r": float(sp_r),
+ })
+
+ # Also try variance-based percentile filtering
+ for pct in [75, 50, 25]:
+ cutoff = np.percentile(cv_vals, pct)
+ mask = cv_vals <= cutoff
+ if mask.sum() < 10:
+ continue
+ sp_r, _ = stats.spearmanr(g_vals[mask], h_vals[mask])
+ records.append({
+ "threshold": f"bottom_{pct}pct_CV",
+ "n_genes": int(mask.sum()),
+ "spearman_r": float(sp_r),
+ })
+
+ results[ref_name] = records
+ print(f"\n {ref_name} half-life:")
+ for r in records:
+ print(f" {r['threshold']:>20s}: r={r['spearman_r']:.4f} (n={r['n_genes']})")
+
+ # Plot improvement
+ fig, axes = plt.subplots(1, 2, figsize=(12, 5))
+ for ax_idx, (ref_name, records) in enumerate(results.items()):
+ if not records:
+ continue
+ labels = [r["threshold"] for r in records]
+ rs = [r["spearman_r"] for r in records]
+ ns = [r["n_genes"] for r in records]
+
+ ax = axes[ax_idx]
+ bars = ax.bar(range(len(labels)), [-r for r in rs], color="steelblue", alpha=0.7)
+ ax.set_xticks(range(len(labels)))
+ ax.set_xticklabels(labels, rotation=45, ha="right", fontsize=8)
+ ax.set_ylabel("|Spearman r| with half-life")
+ ax.set_title(f"{dataset_name}: {ref_name} reference")
+
+ # Annotate with n_genes
+ for i, (bar, n) in enumerate(zip(bars, ns)):
+ ax.text(bar.get_x() + bar.get_width()/2, bar.get_height(),
+ f"n={n}", ha="center", va="bottom", fontsize=7)
+
+ # Highlight improvement
+ if len(rs) > 1:
+ best = max(range(len(rs)), key=lambda i: abs(rs[i]))
+ if best > 0:
+ bars[best].set_color("darkorange")
+
+ fig.suptitle("Uncertainty-guided filtering improves half-life correlation", y=1.02)
+ fig.tight_layout()
+ save_fig(fig, f"{dataset_name}_uncertainty_filtering")
+
+ return results
+
+
+# ============================================================================
+# 2. CELL-SPECIFIC GAMMA RESOLUTION
+# ============================================================================
+
+def advantage_cell_resolution(adata_an, adata_dp, dataset_name, cluster_key="clusters"):
+ """Show DeepPTR captures per-cell gamma variation that smoothed analytical misses.
+
+ The analytical method smoothes Mu/Ms across neighbors, collapsing per-cell variation.
+ DeepPTR infers gamma per-cell from the generative model, preserving heterogeneity
+ at transition states.
+ """
+ print(f"\n{'=' * 60}")
+ print(f"ADVANTAGE 2: Cell-specific gamma resolution ({dataset_name})")
+ print("=" * 60)
+
+ if cluster_key not in adata_an.obs.columns:
+ print(" [SKIP] No cluster key")
+ return None
+
+ shared = adata_an.var_names.intersection(adata_dp.var_names)
+ an_idx = [list(adata_an.var_names).index(g) for g in shared]
+ dp_idx = [list(adata_dp.var_names).index(g) for g in shared]
+
+ cell_types = sorted(adata_an.obs[cluster_key].unique())
+
+ # For each cell type: compare within-cluster gamma CV (coefficient of variation)
+ # Higher CV = more heterogeneity captured
+ records = []
+ for ct in cell_types:
+ mask_an = (adata_an.obs[cluster_key] == ct).values
+ mask_dp = (adata_dp.obs[cluster_key] == ct).values
+
+ if mask_an.sum() < 10 or mask_dp.sum() < 10:
+ continue
+
+ gamma_an_ct = adata_an.layers["gamma"][mask_an][:, an_idx]
+ gamma_dp_ct = adata_dp.layers["gamma"][mask_dp][:, dp_idx]
+
+ # Per-gene CV within this cell type
+ mean_an = gamma_an_ct.mean(axis=0)
+ std_an = gamma_an_ct.std(axis=0)
+ cv_an = np.where(mean_an > 0.01, std_an / mean_an, 0)
+
+ mean_dp = gamma_dp_ct.mean(axis=0)
+ std_dp = gamma_dp_ct.std(axis=0)
+ cv_dp = np.where(mean_dp > 0.01, std_dp / mean_dp, 0)
+
+ # Median CV across genes
+ records.append({
+ "cell_type": str(ct),
+ "n_cells": int(mask_an.sum()),
+ "median_cv_analytical": float(np.median(cv_an)),
+ "median_cv_deepptr": float(np.median(cv_dp)),
+ "mean_cv_analytical": float(np.mean(cv_an)),
+ "mean_cv_deepptr": float(np.mean(cv_dp)),
+ })
+
+ if not records:
+ return None
+
+ df = pd.DataFrame(records)
+ print(f"\n Within-cluster gamma CV (higher = more heterogeneity):")
+ print(f" {'Cell type':<25} {'Analytical':>12} {'DeepPTR':>12} {'Ratio':>8}")
+ for _, row in df.iterrows():
+ ratio = row["median_cv_deepptr"] / max(row["median_cv_analytical"], 1e-8)
+ print(f" {row['cell_type']:<25} {row['median_cv_analytical']:>12.4f} "
+ f"{row['median_cv_deepptr']:>12.4f} {ratio:>8.2f}x")
+
+ # Inter-vs-intra cluster variance ratio (a.k.a. "signal to noise")
+ # If DeepPTR captures real biological variation, its inter/intra ratio
+ # should be similar or better than analytical
+ gamma_an_shared = adata_an.layers["gamma"][:, an_idx]
+ gamma_dp_shared = adata_dp.layers["gamma"][:, dp_idx]
+ labels = adata_an.obs[cluster_key].values
+
+ # F-statistic per gene (one-way ANOVA: do cell types differ?)
+ from scipy.stats import f_oneway
+ n_sig_an = 0
+ n_sig_dp = 0
+ n_tested = 0
+ f_stats_an = []
+ f_stats_dp = []
+
+ for g in range(len(shared)):
+ groups_an = [gamma_an_shared[labels == ct, g] for ct in cell_types
+ if (labels == ct).sum() >= 5]
+ groups_dp = [gamma_dp_shared[adata_dp.obs[cluster_key].values == ct, g]
+ for ct in cell_types
+ if (adata_dp.obs[cluster_key].values == ct).sum() >= 5]
+
+ if len(groups_an) < 2 or len(groups_dp) < 2:
+ continue
+
+ # Only test if there's signal
+ if np.std(gamma_an_shared[:, g]) < 1e-6 and np.std(gamma_dp_shared[:, g]) < 1e-6:
+ continue
+
+ n_tested += 1
+ try:
+ f_an, p_an = f_oneway(*groups_an)
+ f_dp, p_dp = f_oneway(*groups_dp)
+ f_stats_an.append(f_an)
+ f_stats_dp.append(f_dp)
+ if p_an < 0.05:
+ n_sig_an += 1
+ if p_dp < 0.05:
+ n_sig_dp += 1
+ except Exception:
+ pass
+
+ print(f"\n Cell-type-specific gamma (ANOVA, {n_tested} genes):")
+ print(f" Analytical: {n_sig_an}/{n_tested} genes significant (p<0.05)")
+ print(f" DeepPTR: {n_sig_dp}/{n_tested} genes significant (p<0.05)")
+ if f_stats_an and f_stats_dp:
+ print(f" Median F-stat: analytical={np.median(f_stats_an):.2f}, "
+ f"DeepPTR={np.median(f_stats_dp):.2f}")
+
+ result = {
+ "per_celltype_cv": records,
+ "anova_n_tested": n_tested,
+ "anova_n_sig_analytical": n_sig_an,
+ "anova_n_sig_deepptr": n_sig_dp,
+ "anova_median_F_analytical": float(np.median(f_stats_an)) if f_stats_an else None,
+ "anova_median_F_deepptr": float(np.median(f_stats_dp)) if f_stats_dp else None,
+ }
+
+ # Plot: scatter of F-statistics
+ if f_stats_an and f_stats_dp:
+ fig, axes = plt.subplots(1, 2, figsize=(12, 5))
+
+ # F-statistic comparison
+ ax = axes[0]
+ min_len = min(len(f_stats_an), len(f_stats_dp))
+ ax.scatter(f_stats_an[:min_len], f_stats_dp[:min_len], alpha=0.3, s=8, c="steelblue")
+ lim = max(max(f_stats_an[:min_len]), max(f_stats_dp[:min_len]))
+ ax.plot([0, lim], [0, lim], "k--", alpha=0.3)
+ ax.set_xlabel("Analytical F-statistic")
+ ax.set_ylabel("DeepPTR F-statistic")
+ ax.set_title(f"Cell-type discrimination per gene")
+ ax.set_xscale("log")
+ ax.set_yscale("log")
+
+ # CV comparison
+ ax = axes[1]
+ ax.bar(range(len(df)), df["median_cv_analytical"], width=0.4,
+ label="Analytical", alpha=0.7, color="steelblue")
+ ax.bar([x + 0.4 for x in range(len(df))], df["median_cv_deepptr"], width=0.4,
+ label="DeepPTR", alpha=0.7, color="darkorange")
+ ax.set_xticks([x + 0.2 for x in range(len(df))])
+ ax.set_xticklabels(df["cell_type"], rotation=45, ha="right", fontsize=7)
+ ax.set_ylabel("Median within-cluster gamma CV")
+ ax.set_title(f"Per-cell heterogeneity")
+ ax.legend()
+
+ fig.suptitle(f"{dataset_name}: Cell-specific gamma resolution", y=1.02)
+ fig.tight_layout()
+ save_fig(fig, f"{dataset_name}_cell_resolution")
+
+ return result
+
+
+# ============================================================================
+# 3. LATENT DISENTANGLEMENT DISCOVERS PT PROGRAMS
+# ============================================================================
+
+def advantage_disentanglement(adata_dp, dataset_name, cluster_key="clusters"):
+ """Show z_PT captures post-transcriptional programs invisible in expression.
+
+ z_T captures transcriptional identity (cell type).
+ z_PT captures orthogonal post-transcriptional regulation.
+ Genes loading on z_PT but not z_T reveal PT-specific regulation.
+ """
+ print(f"\n{'=' * 60}")
+ print(f"ADVANTAGE 3: Latent disentanglement ({dataset_name})")
+ print("=" * 60)
+
+ z_T = adata_dp.obsm["X_z_T"]
+ z_PT = adata_dp.obsm["X_z_PT"]
+ gamma = adata_dp.layers["gamma"]
+
+ # 1. Correlation of each gene's gamma with z_T vs z_PT
+ # Genes correlated with z_PT but not z_T are PT-specific
+ r_T = np.zeros(adata_dp.n_vars)
+ r_PT = np.zeros(adata_dp.n_vars)
+
+ for g in range(adata_dp.n_vars):
+ gv = gamma[:, g]
+ if gv.std() < 1e-8:
+ continue
+ # Max absolute correlation with any z_T dimension
+ r_T[g] = max(abs(stats.spearmanr(gv, z_T[:, d]).statistic)
+ for d in range(z_T.shape[1]))
+ r_PT[g] = max(abs(stats.spearmanr(gv, z_PT[:, d]).statistic)
+ for d in range(z_PT.shape[1]))
+
+ # Genes specifically correlated with z_PT
+ pt_specific_mask = (r_PT > 0.3) & (r_PT > r_T * 1.5)
+ t_specific_mask = (r_T > 0.3) & (r_T > r_PT * 1.5)
+
+ pt_genes = adata_dp.var_names[pt_specific_mask].tolist()
+ t_genes = adata_dp.var_names[t_specific_mask].tolist()
+
+ print(f"\n PT-specific genes (r_PT>0.3, r_PT>1.5*r_T): {len(pt_genes)}")
+ if pt_genes:
+ print(f" Top PT genes: {pt_genes[:15]}")
+ print(f" T-specific genes (r_T>0.3, r_T>1.5*r_PT): {len(t_genes)}")
+ if t_genes:
+ print(f" Top T genes: {t_genes[:15]}")
+
+ # 2. Cluster in z_PT space to find PT states
+ from sklearn.cluster import KMeans
+ n_pt_clusters = min(5, max(2, len(set(adata_dp.obs.get(cluster_key, []))) // 2))
+ km = KMeans(n_clusters=n_pt_clusters, random_state=0, n_init=10)
+ pt_labels = km.fit_predict(z_PT)
+ adata_dp.obs["pt_cluster_deep"] = pd.Categorical([f"PT_{i}" for i in pt_labels])
+
+ # 3. Compare: do PT clusters align with expression clusters?
+ if cluster_key in adata_dp.obs.columns:
+ from sklearn.metrics import adjusted_rand_score, normalized_mutual_info_score
+ expr_labels = adata_dp.obs[cluster_key].astype("category").cat.codes.values
+ ari = adjusted_rand_score(expr_labels, pt_labels)
+ nmi = normalized_mutual_info_score(expr_labels, pt_labels)
+ print(f"\n PT clusters vs expression clusters:")
+ print(f" ARI = {ari:.4f} (0=random, 1=identical)")
+ print(f" NMI = {nmi:.4f}")
+ print(f" → {'Low' if ari < 0.3 else 'Moderate' if ari < 0.6 else 'High'} "
+ f"overlap: PT space captures {'different' if ari < 0.3 else 'partially overlapping'} structure")
+ else:
+ ari = nmi = None
+
+ # 4. Find genes differentially degraded between PT clusters
+ # (these are genes whose degradation rate differs for reasons orthogonal to expression)
+ from scipy.stats import kruskal
+ pt_de_genes = []
+ for g in range(adata_dp.n_vars):
+ groups = [gamma[pt_labels == k, g] for k in range(n_pt_clusters)]
+ groups = [grp for grp in groups if len(grp) >= 5]
+ if len(groups) < 2:
+ continue
+ try:
+ h_stat, p_val = kruskal(*groups)
+ if p_val < 0.01:
+ effect = np.max([np.median(grp) for grp in groups]) / max(np.min([np.median(grp) for grp in groups]), 1e-8)
+ pt_de_genes.append({
+ "gene": adata_dp.var_names[g],
+ "H_statistic": float(h_stat),
+ "p_value": float(p_val),
+ "fold_change": float(effect),
+ })
+ except Exception:
+ pass
+
+ pt_de_genes.sort(key=lambda x: x["p_value"])
+ print(f"\n Genes differentially degraded between PT clusters: {len(pt_de_genes)}")
+ if pt_de_genes:
+ print(f" Top 10:")
+ for g in pt_de_genes[:10]:
+ print(f" {g['gene']:<15} H={g['H_statistic']:.1f} p={g['p_value']:.2e} FC={g['fold_change']:.2f}")
+
+ result = {
+ "n_pt_specific_genes": len(pt_genes),
+ "pt_specific_genes": pt_genes[:50],
+ "n_t_specific_genes": len(t_genes),
+ "t_specific_genes": t_genes[:50],
+ "pt_vs_expr_ari": float(ari) if ari is not None else None,
+ "pt_vs_expr_nmi": float(nmi) if nmi is not None else None,
+ "n_pt_de_genes": len(pt_de_genes),
+ "top_pt_de_genes": pt_de_genes[:20],
+ }
+
+ # Plot
+ fig, axes = plt.subplots(1, 3, figsize=(16, 5))
+
+ # Panel 1: r_T vs r_PT scatter
+ ax = axes[0]
+ ax.scatter(r_T, r_PT, alpha=0.3, s=8, c="gray")
+ if pt_specific_mask.any():
+ ax.scatter(r_T[pt_specific_mask], r_PT[pt_specific_mask],
+ alpha=0.7, s=15, c="darkorange", label=f"PT-specific ({len(pt_genes)})")
+ if t_specific_mask.any():
+ ax.scatter(r_T[t_specific_mask], r_PT[t_specific_mask],
+ alpha=0.7, s=15, c="steelblue", label=f"T-specific ({len(t_genes)})")
+ ax.plot([0, 1], [0, 1], "k--", alpha=0.3)
+ ax.set_xlabel("Max |r| with z_T")
+ ax.set_ylabel("Max |r| with z_PT")
+ ax.set_title("Gene regulation mode")
+ ax.legend(fontsize=8)
+
+ # Panel 2: z_PT PCA colored by PT cluster
+ from sklearn.decomposition import PCA
+ z_2d = PCA(n_components=2).fit_transform(z_PT)
+ cmap = plt.colormaps.get_cmap("Set2")
+ ax = axes[1]
+ for k in range(n_pt_clusters):
+ mask = pt_labels == k
+ ax.scatter(z_2d[mask, 0], z_2d[mask, 1], alpha=0.3, s=5,
+ c=[cmap(k)], label=f"PT_{k}")
+ ax.set_title("z_PT space (PT clusters)")
+ ax.set_xlabel("PC1")
+ ax.set_ylabel("PC2")
+ ax.legend(fontsize=7, markerscale=3)
+
+ # Panel 3: z_PT colored by expression cluster
+ ax = axes[2]
+ if cluster_key in adata_dp.obs.columns:
+ cats = adata_dp.obs[cluster_key].astype("category")
+ codes = cats.cat.codes.values
+ n_cats = len(cats.cat.categories)
+ cmap_expr = plt.colormaps.get_cmap("tab20")
+ for i, cat in enumerate(cats.cat.categories):
+ mask = codes == i
+ ax.scatter(z_2d[mask, 0], z_2d[mask, 1], alpha=0.3, s=5,
+ c=[cmap_expr(i / n_cats)], label=str(cat))
+ ax.set_title(f"z_PT space (expression clusters)\nARI={ari:.3f}")
+ if n_cats <= 12:
+ ax.legend(fontsize=6, markerscale=3, ncol=2)
+ ax.set_xlabel("PC1")
+ ax.set_ylabel("PC2")
+
+ fig.suptitle(f"{dataset_name}: Latent disentanglement", y=1.02)
+ fig.tight_layout()
+ save_fig(fig, f"{dataset_name}_disentanglement")
+
+ return result
+
+
+# ============================================================================
+# 4. POSTERIOR-BASED STATISTICAL TESTING
+# ============================================================================
+
+def advantage_statistical_testing(adata_dp, dataset_name, cluster_key="clusters"):
+ """Demonstrate posterior-based statistical testing of gamma differences.
+
+ With DeepPTR, we can compute credible intervals for gamma differences
+ between cell types — something impossible with a point estimate.
+ """
+ print(f"\n{'=' * 60}")
+ print(f"ADVANTAGE 4: Posterior-based statistical testing ({dataset_name})")
+ print("=" * 60)
+
+ if cluster_key not in adata_dp.obs.columns:
+ print(" [SKIP] No cluster key")
+ return None
+
+ gamma = adata_dp.layers["gamma"]
+ gamma_var = adata_dp.layers["gamma_var"]
+
+ cell_types = sorted(adata_dp.obs[cluster_key].unique())
+ if len(cell_types) < 2:
+ return None
+
+ # Pick two cell types to compare
+ # Choose the pair with most cells
+ ct_sizes = {ct: (adata_dp.obs[cluster_key] == ct).sum() for ct in cell_types}
+ sorted_cts = sorted(ct_sizes.keys(), key=lambda x: ct_sizes[x], reverse=True)
+ ct_a, ct_b = sorted_cts[0], sorted_cts[1]
+
+ mask_a = (adata_dp.obs[cluster_key] == ct_a).values
+ mask_b = (adata_dp.obs[cluster_key] == ct_b).values
+
+ gamma_a = gamma[mask_a]
+ gamma_b = gamma[mask_b]
+ var_a = gamma_var[mask_a]
+ var_b = gamma_var[mask_b]
+
+ # Per-gene: test if mean gamma differs between cell types
+ # Use posterior: mean_diff ~ N(mu_a - mu_b, var_a/n_a + var_b/n_b)
+ n_a, n_b = mask_a.sum(), mask_b.sum()
+ mean_a = gamma_a.mean(axis=0)
+ mean_b = gamma_b.mean(axis=0)
+ # Posterior variance of the mean
+ var_mean_a = var_a.mean(axis=0) / n_a
+ var_mean_b = var_b.mean(axis=0) / n_b
+
+ diff = mean_a - mean_b
+ diff_se = np.sqrt(var_mean_a + var_mean_b + 1e-10)
+ z_score = diff / diff_se
+
+ # Two-sided test
+ p_vals = 2 * (1 - stats.norm.cdf(np.abs(z_score)))
+
+ # Compare with simple t-test (no uncertainty info)
+ from scipy.stats import ttest_ind
+ p_ttest = np.zeros(adata_dp.n_vars)
+ for g in range(adata_dp.n_vars):
+ try:
+ _, p_ttest[g] = ttest_ind(gamma_a[:, g], gamma_b[:, g])
+ except Exception:
+ p_ttest[g] = 1.0
+
+ # Count significant at FDR 0.05
+ from statsmodels.stats.multitest import multipletests
+ _, p_adj_post, _, _ = multipletests(p_vals, method="fdr_bh")
+ _, p_adj_ttest, _, _ = multipletests(p_ttest, method="fdr_bh")
+
+ n_sig_post = (p_adj_post < 0.05).sum()
+ n_sig_ttest = (p_adj_ttest < 0.05).sum()
+
+ print(f"\n Comparing {ct_a} ({n_a} cells) vs {ct_b} ({n_b} cells):")
+ print(f" Posterior-informed test: {n_sig_post}/{adata_dp.n_vars} genes significant (FDR<0.05)")
+ print(f" Simple t-test: {n_sig_ttest}/{adata_dp.n_vars} genes significant (FDR<0.05)")
+
+ # Identify genes found by posterior but not by t-test (and vice versa)
+ post_only = (p_adj_post < 0.05) & (p_adj_ttest >= 0.05)
+ ttest_only = (p_adj_ttest < 0.05) & (p_adj_post >= 0.05)
+ both = (p_adj_post < 0.05) & (p_adj_ttest < 0.05)
+
+ print(f" Both: {both.sum()}")
+ print(f" Posterior-only: {post_only.sum()}")
+ print(f" T-test-only: {ttest_only.sum()}")
+
+ result = {
+ "ct_a": str(ct_a),
+ "ct_b": str(ct_b),
+ "n_cells_a": int(n_a),
+ "n_cells_b": int(n_b),
+ "n_sig_posterior": int(n_sig_post),
+ "n_sig_ttest": int(n_sig_ttest),
+ "n_both": int(both.sum()),
+ "n_posterior_only": int(post_only.sum()),
+ "n_ttest_only": int(ttest_only.sum()),
+ }
+
+ # If posterior finds additional genes, list them
+ if post_only.any():
+ post_only_genes = adata_dp.var_names[post_only].tolist()
+ print(f"\n Posterior-only genes (uncertainty-aware):")
+ for g in post_only_genes[:10]:
+ idx = list(adata_dp.var_names).index(g)
+ print(f" {g}: diff={diff[idx]:.4f} ± {diff_se[idx]:.4f}")
+ result["posterior_only_genes"] = post_only_genes[:20]
+
+ # Plot
+ fig, axes = plt.subplots(1, 2, figsize=(12, 5))
+
+ ax = axes[0]
+ ax.scatter(-np.log10(p_ttest + 1e-300), -np.log10(p_vals + 1e-300),
+ alpha=0.2, s=5, c="gray")
+ if post_only.any():
+ ax.scatter(-np.log10(p_ttest[post_only] + 1e-300),
+ -np.log10(p_vals[post_only] + 1e-300),
+ alpha=0.7, s=15, c="darkorange", label="Posterior-only")
+ if ttest_only.any():
+ ax.scatter(-np.log10(p_ttest[ttest_only] + 1e-300),
+ -np.log10(p_vals[ttest_only] + 1e-300),
+ alpha=0.7, s=15, c="steelblue", label="T-test-only")
+ ax.set_xlabel("-log10(p) t-test")
+ ax.set_ylabel("-log10(p) posterior")
+ ax.set_title(f"{ct_a} vs {ct_b}")
+ ax.plot([0, 20], [0, 20], "k--", alpha=0.3)
+ ax.legend(fontsize=8)
+
+ # Volcano plot with uncertainty
+ ax = axes[1]
+ sig = p_adj_post < 0.05
+ ax.scatter(diff[~sig], -np.log10(p_vals[~sig] + 1e-300),
+ alpha=0.1, s=3, c="gray")
+ ax.scatter(diff[sig], -np.log10(p_vals[sig] + 1e-300),
+ alpha=0.5, s=8, c="darkorange")
+ ax.set_xlabel(f"Mean gamma difference ({ct_a} - {ct_b})")
+ ax.set_ylabel("-log10(p)")
+ ax.set_title(f"Posterior volcano ({n_sig_post} significant)")
+ ax.axhline(-np.log10(0.05), color="red", ls="--", alpha=0.3)
+
+ fig.suptitle(f"{dataset_name}: Posterior-based differential degradation", y=1.02)
+ fig.tight_layout()
+ save_fig(fig, f"{dataset_name}_posterior_testing")
+
+ return result
+
+
+# ============================================================================
+# MAIN
+# ============================================================================
+
+def main():
+ set_figure_style()
+ ensure_dirs()
+
+ datasets = [
+ ("pancreas", scptr.datasets.pancreas, "clusters"),
+ ("dentate_gyrus", scptr.datasets.dentate_gyrus, "clusters"),
+ ]
+
+ all_results = {}
+
+ for name, loader, cluster_key in datasets:
+ print(f"\n{'#' * 60}")
+ print(f"# {name.upper()}")
+ print(f"{'#' * 60}")
+
+ adata_an, adata_dp, model = prepare_both(loader, n_top=300)
+
+ results = {}
+
+ # 1. Uncertainty-guided filtering
+ results["uncertainty_filtering"] = advantage_uncertainty_filtering(adata_dp, name)
+
+ # 2. Cell-specific gamma
+ results["cell_resolution"] = advantage_cell_resolution(adata_an, adata_dp, name, cluster_key)
+
+ # 3. Latent disentanglement
+ results["disentanglement"] = advantage_disentanglement(adata_dp, name, cluster_key)
+
+ # 4. Posterior testing
+ results["statistical_testing"] = advantage_statistical_testing(adata_dp, name, cluster_key)
+
+ all_results[name] = results
+
+ with open(OUTPUT_DIR / "results" / f"{name}_advantages.json", "w") as f:
+ json.dump(results, f, indent=2, default=str)
+
+ # Summary
+ print(f"\n{'=' * 70}")
+ print("DEEPPTR UNIQUE ADVANTAGES SUMMARY")
+ print("=" * 70)
+
+ for name, results in all_results.items():
+ print(f"\n {name.upper()}")
+
+ # Uncertainty filtering
+ uf = results.get("uncertainty_filtering", {})
+ for ref, records in uf.items():
+ if records:
+ r_all = records[0]["spearman_r"]
+ r_best = min(records, key=lambda x: x["spearman_r"]) # most negative
+ improvement = abs(r_best["spearman_r"]) - abs(r_all)
+ print(f" Uncertainty filtering ({ref}): {r_all:.4f} → {r_best['spearman_r']:.4f} "
+ f"(+{improvement:.4f} at {r_best['threshold']})")
+
+ # Cell resolution
+ cr = results.get("cell_resolution", {})
+ if cr:
+ print(f" Cell-type ANOVA: analytical={cr['anova_n_sig_analytical']}, "
+ f"DeepPTR={cr['anova_n_sig_deepptr']} significant genes")
+
+ # Disentanglement
+ dis = results.get("disentanglement", {})
+ if dis:
+ print(f" PT-specific genes: {dis['n_pt_specific_genes']}, "
+ f"T-specific: {dis['n_t_specific_genes']}")
+ if dis.get("pt_vs_expr_ari") is not None:
+ print(f" PT vs expr overlap: ARI={dis['pt_vs_expr_ari']:.4f} "
+ f"({'orthogonal' if dis['pt_vs_expr_ari'] < 0.2 else 'partially overlapping'})")
+ print(f" DE genes between PT clusters: {dis['n_pt_de_genes']}")
+
+ # Statistical testing
+ st = results.get("statistical_testing", {})
+ if st:
+ print(f" Posterior testing ({st['ct_a']} vs {st['ct_b']}): "
+ f"{st['n_sig_posterior']} posterior, {st['n_sig_ttest']} t-test, "
+ f"{st['n_posterior_only']} posterior-only")
+
+ # Save combined
+ with open(OUTPUT_DIR / "results" / "combined_advantages.json", "w") as f:
+ json.dump(all_results, f, indent=2, default=str)
+
+ print(f"\nAll results saved to: {OUTPUT_DIR}")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_mirna_analysis.py b/analyses/run_mirna_analysis.py
new file mode 100644
index 0000000000000000000000000000000000000000..26cae58bd1bbcb152ecfe14486fe050a26f1e1f8
--- /dev/null
+++ b/analyses/run_mirna_analysis.py
@@ -0,0 +1,281 @@
+#!/usr/bin/env python
+"""miRNA-target analysis: test whether miRNA-targeted genes have higher gamma.
+
+Uses TargetScan 8.0 predictions to identify miRNA-target relationships,
+then tests whether predicted targets have systematically higher degradation
+rates (gamma) than non-targets using Mann-Whitney U tests.
+
+This addresses Aim 4 of the research plan: post-transcriptional regulatory networks.
+"""
+
+from __future__ import annotations
+
+import json
+import sys
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+from scipy import stats
+
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style
+
+import scptr
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output" / "mirna_analysis"
+
+
+def save_fig(fig, name, subdir="figures"):
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+def run_mirna_analysis(adata, dataset_name, mirna_targets):
+ """Run miRNA-gamma correlation analysis on a dataset."""
+ print(f"\n{'='*60}")
+ print(f"miRNA ANALYSIS: {dataset_name}")
+ print(f"{'='*60}")
+
+ # Run scPTR pipeline
+ import copy
+ adata = copy.deepcopy(adata)
+ scptr.pp.filter_genes(adata)
+ scptr.pp.normalize_layers(adata)
+ scptr.pp.neighbors(adata, n_neighbors=30)
+ scptr.pp.smooth_layers(adata)
+ scptr.tl.estimate_beta(adata)
+ scptr.tl.estimate_gamma(adata)
+
+ # Run miRNA-gamma correlation
+ print(f" Running miRNA-gamma correlation...")
+ result_df = scptr.tl.mirna_gamma_correlation(
+ adata, mirna_targets, n_top_targets=200, min_cells_expressing=50
+ )
+
+ if len(result_df) == 0:
+ print(f" No miRNA families with sufficient targets found.")
+ return None
+
+ # Summary statistics
+ n_tested = len(result_df)
+ n_sig = (result_df["fdr"] < 0.05).sum()
+ n_sig_10 = (result_df["fdr"] < 0.10).sum()
+ n_enriched = (result_df["fold_enrichment"] > 1.0).sum()
+
+ print(f"\n Results:")
+ print(f" miRNA families tested: {n_tested}")
+ print(f" Significant (FDR < 0.05): {n_sig} ({100*n_sig/n_tested:.1f}%)")
+ print(f" Significant (FDR < 0.10): {n_sig_10} ({100*n_sig_10/n_tested:.1f}%)")
+ print(f" Enriched (fold > 1.0): {n_enriched} ({100*n_enriched/n_tested:.1f}%)")
+ print(f" Median fold enrichment: {result_df['fold_enrichment'].median():.3f}")
+
+ # Top significant miRNAs
+ top_sig = result_df[result_df["fdr"] < 0.10].head(20)
+ if len(top_sig) > 0:
+ print(f"\n Top significant miRNAs (FDR < 0.10):")
+ for _, row in top_sig.iterrows():
+ print(f" {row['representative_mirna']:>25s} "
+ f"n_targets={row['n_targets_in_data']:3d} "
+ f"fold={row['fold_enrichment']:.2f} "
+ f"p={row['mannwhitney_p']:.2e} "
+ f"FDR={row['fdr']:.3f}")
+
+ # Top miRNAs by effect size regardless of significance
+ top_effect = result_df.nlargest(10, "fold_enrichment")
+ print(f"\n Top miRNAs by fold enrichment:")
+ for _, row in top_effect.iterrows():
+ print(f" {row['representative_mirna']:>25s} "
+ f"fold={row['fold_enrichment']:.2f} "
+ f"FDR={row['fdr']:.3f}")
+
+ # Aggregate test: all miRNA targets vs non-targets
+ gamma = np.median(adata.layers["gamma"], axis=0)
+ gene_names_upper = [g.upper() for g in adata.var_names]
+
+ all_target_genes = set()
+ for _, row in mirna_targets.iterrows():
+ all_target_genes.add(str(row["gene_symbol"]).upper())
+
+ informative = (adata.layers["gamma"] > 0).mean(axis=0) >= 0.1
+ target_gamma = []
+ nontarget_gamma = []
+ for i, g in enumerate(gene_names_upper):
+ if not informative[i]:
+ continue
+ if g in all_target_genes:
+ target_gamma.append(gamma[i])
+ else:
+ nontarget_gamma.append(gamma[i])
+
+ if len(target_gamma) >= 10 and len(nontarget_gamma) >= 10:
+ u, p = stats.mannwhitneyu(target_gamma, nontarget_gamma, alternative="greater")
+ print(f"\n Aggregate test (all targets vs non-targets):")
+ print(f" Target genes in data: {len(target_gamma)}")
+ print(f" Non-target genes: {len(nontarget_gamma)}")
+ print(f" Target median gamma: {np.median(target_gamma):.6f}")
+ print(f" Non-target median gamma: {np.median(nontarget_gamma):.6f}")
+ print(f" Fold: {np.median(target_gamma) / (np.median(nontarget_gamma) + 1e-8):.3f}")
+ print(f" Mann-Whitney p: {p:.2e}")
+
+ # Save results
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+ result_df.to_csv(res_dir / f"mirna_gamma_{dataset_name}.csv", index=False)
+
+ # Figures
+ fig, axes = plt.subplots(1, 3, figsize=(16, 5))
+
+ # Panel 1: Volcano plot (fold enrichment vs -log10 p)
+ neg_log_p = -np.log10(result_df["mannwhitney_p"].clip(lower=1e-50))
+ sig_mask = result_df["fdr"] < 0.05
+ axes[0].scatter(result_df["fold_enrichment"][~sig_mask], neg_log_p[~sig_mask],
+ s=10, alpha=0.3, color="gray", label="NS")
+ axes[0].scatter(result_df["fold_enrichment"][sig_mask], neg_log_p[sig_mask],
+ s=20, alpha=0.7, color="red", label=f"FDR<0.05 (n={sig_mask.sum()})")
+ axes[0].axhline(y=-np.log10(0.05), color="blue", linestyle="--", alpha=0.5)
+ axes[0].axvline(x=1.0, color="black", linestyle="--", alpha=0.3)
+ axes[0].set_xlabel("Fold enrichment (target/non-target gamma)")
+ axes[0].set_ylabel("-log10(p)")
+ axes[0].set_title(f"miRNA Target Enrichment ({dataset_name})")
+ axes[0].legend()
+
+ # Panel 2: Distribution of fold enrichments
+ axes[1].hist(result_df["fold_enrichment"], bins=30, color="steelblue",
+ edgecolor="black", linewidth=0.5)
+ axes[1].axvline(x=1.0, color="red", linestyle="--", label="No enrichment")
+ axes[1].axvline(x=result_df["fold_enrichment"].median(), color="green",
+ linestyle="--", label=f"Median={result_df['fold_enrichment'].median():.2f}")
+ axes[1].set_xlabel("Fold enrichment")
+ axes[1].set_ylabel("Count")
+ axes[1].set_title("Distribution of Fold Enrichments")
+ axes[1].legend()
+
+ # Panel 3: Aggregate target vs non-target boxplot
+ if len(target_gamma) >= 10:
+ box_data = [target_gamma, nontarget_gamma]
+ bp = axes[2].boxplot(box_data, labels=["miRNA\ntargets", "Non-\ntargets"],
+ patch_artist=True)
+ bp["boxes"][0].set_facecolor("coral")
+ bp["boxes"][1].set_facecolor("lightblue")
+ axes[2].set_ylabel("Median gamma per gene")
+ axes[2].set_title(f"Aggregate: targets vs non-targets\np={p:.2e}")
+ axes[2].set_yscale("symlog", linthresh=0.001)
+
+ fig.suptitle(f"miRNA-Gamma Analysis: {dataset_name}", fontsize=13, y=1.02)
+ fig.tight_layout()
+ save_fig(fig, f"mirna_analysis_{dataset_name}")
+
+ return {
+ "n_families_tested": n_tested,
+ "n_significant_005": int(n_sig),
+ "n_significant_010": int(n_sig_10),
+ "n_enriched": int(n_enriched),
+ "median_fold_enrichment": float(result_df["fold_enrichment"].median()),
+ "aggregate_p": float(p) if len(target_gamma) >= 10 else None,
+ }
+
+
+def main():
+ set_figure_style()
+ OUTPUT_DIR.mkdir(parents=True, exist_ok=True)
+
+ # Load TargetScan predictions
+ print("=" * 60)
+ print("LOADING TARGETSCAN PREDICTIONS")
+ print("=" * 60)
+
+ cache_dir = Path(__file__).parent.parent / ".cache" / "targetscan"
+ try:
+ mirna_targets = scptr.tl.load_targetscan_predictions(
+ species_id=9606, # Human
+ min_context_score=-0.2,
+ cache_dir=cache_dir,
+ )
+ print(f" Loaded {len(mirna_targets)} human miRNA-target predictions")
+ print(f" miRNA families: {mirna_targets['mirna_family'].nunique()}")
+ print(f" Target genes: {mirna_targets['gene_symbol'].nunique()}")
+ except FileNotFoundError as e:
+ print(f" ERROR: {e}")
+ print(" Please download TargetScan data first.")
+ sys.exit(1)
+
+ # Also load mouse predictions for mouse datasets
+ try:
+ mirna_targets_mouse = scptr.tl.load_targetscan_predictions(
+ species_id=10090, # Mouse
+ min_context_score=-0.2,
+ cache_dir=cache_dir,
+ )
+ print(f" Loaded {len(mirna_targets_mouse)} mouse miRNA-target predictions")
+ print(f" miRNA families: {mirna_targets_mouse['mirna_family'].nunique()}")
+ print(f" Target genes: {mirna_targets_mouse['gene_symbol'].nunique()}")
+ except Exception as e:
+ print(f" Mouse predictions not available: {e}")
+ mirna_targets_mouse = mirna_targets # Fallback: use human
+
+ # Load datasets
+ print("\n" + "=" * 60)
+ print("LOADING DATASETS")
+ print("=" * 60)
+
+ adata_pan = scptr.datasets.pancreas()
+ adata_dg = scptr.datasets.dentate_gyrus()
+
+ # Try to load sci-fate
+ try:
+ adata_sci = scptr.datasets.sci_fate()
+ except Exception:
+ adata_sci = None
+
+ # Run analysis on each dataset
+ all_results = {}
+
+ # Pancreas (mouse) - use mouse predictions
+ all_results["pancreas"] = run_mirna_analysis(
+ adata_pan, "pancreas", mirna_targets_mouse
+ )
+
+ # Dentate Gyrus (mouse) - use mouse predictions
+ all_results["dentate_gyrus"] = run_mirna_analysis(
+ adata_dg, "dentate_gyrus", mirna_targets_mouse
+ )
+
+ # sci-fate (human A549) - use human predictions
+ if adata_sci is not None:
+ all_results["sci_fate"] = run_mirna_analysis(
+ adata_sci, "sci_fate", mirna_targets
+ )
+
+ # Save summary
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+ with open(res_dir / "mirna_summary.json", "w") as f:
+ json.dump(all_results, f, indent=2)
+
+ # Summary table
+ print(f"\n{'='*60}")
+ print("miRNA ANALYSIS SUMMARY")
+ print(f"{'='*60}")
+ print(f"{'Dataset':>15s} {'Tested':>7s} {'Sig(5%)':>7s} {'Sig(10%)':>8s} "
+ f"{'Enriched':>8s} {'Med.Fold':>8s} {'Agg.p':>10s}")
+ for name, res in all_results.items():
+ if res is None:
+ continue
+ print(f"{name:>15s} {res['n_families_tested']:>7d} "
+ f"{res['n_significant_005']:>7d} {res['n_significant_010']:>8d} "
+ f"{res['n_enriched']:>8d} {res['median_fold_enrichment']:>8.3f} "
+ f"{res['aggregate_p']:>10.2e}" if res['aggregate_p'] else "")
+
+ print(f"\nResults saved to: {OUTPUT_DIR.resolve()}")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_precedence.py b/analyses/run_precedence.py
new file mode 100644
index 0000000000000000000000000000000000000000..4787cfc302a7dfda96259301d05e958aa9c4b4c3
--- /dev/null
+++ b/analyses/run_precedence.py
@@ -0,0 +1,455 @@
+#!/usr/bin/env python
+"""Demonstrate that PT velocity precedes RNA velocity at cell fate transitions.
+
+Central hypothesis: Post-transcriptional regulation (gamma changes) acts as an
+early signal that precedes and potentially drives transcriptional changes during
+cell fate transitions.
+
+Strategy:
+1. Order cells along pseudotime (diffusion pseudotime via scanpy)
+2. Smooth gamma and expression along pseudotime
+3. For transition-associated genes, detect when gamma change and expression
+ change begin — gamma onset should precede expression onset
+4. Cross-correlation analysis: gamma(t) should predict expression(t+delta)
+"""
+
+from __future__ import annotations
+
+import json
+import sys
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+import scanpy as sc
+from scipy import stats, signal, ndimage
+
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style
+
+import scptr
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output" / "precedence"
+
+
+def save_fig(fig, name, subdir="figures"):
+ if fig is None:
+ return
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+def compute_pseudotime(adata, root_cluster):
+ """Compute diffusion pseudotime from a root cluster."""
+ # Use diffusion pseudotime via scanpy
+ sc.tl.diffmap(adata)
+
+ # Find root cell: centroid of root cluster in diffusion space
+ root_mask = adata.obs["clusters"] == root_cluster
+ root_cells = np.where(root_mask)[0]
+ if len(root_cells) == 0:
+ raise ValueError(f"No cells in cluster {root_cluster}")
+
+ # Pick cell closest to cluster centroid in diffmap
+ dm = adata.obsm["X_diffmap"]
+ centroid = dm[root_cells].mean(axis=0)
+ dists = np.linalg.norm(dm[root_cells] - centroid, axis=1)
+ root_idx = root_cells[np.argmin(dists)]
+
+ adata.uns["iroot"] = root_idx
+ sc.tl.dpt(adata)
+
+ pt = adata.obs["dpt_pseudotime"].values.copy()
+ # Handle infinite values
+ pt[~np.isfinite(pt)] = np.nanmax(pt[np.isfinite(pt)])
+ return pt
+
+
+def smooth_along_pseudotime(values, pseudotime, n_bins=100):
+ """Bin and smooth values along pseudotime axis.
+
+ Returns bin centers and smoothed values (per gene if 2D).
+ """
+ bins = np.linspace(0, np.max(pseudotime), n_bins + 1)
+ bin_centers = (bins[:-1] + bins[1:]) / 2
+ bin_idx = np.digitize(pseudotime, bins) - 1
+ bin_idx = np.clip(bin_idx, 0, n_bins - 1)
+
+ if values.ndim == 1:
+ smoothed = np.zeros(n_bins)
+ for i in range(n_bins):
+ mask = bin_idx == i
+ if mask.sum() > 0:
+ smoothed[i] = np.mean(values[mask])
+ # Gaussian smoothing
+ smoothed = ndimage.gaussian_filter1d(smoothed, sigma=2)
+ return bin_centers, smoothed
+
+ # 2D: genes x bins
+ n_genes = values.shape[1]
+ smoothed = np.zeros((n_bins, n_genes))
+ for i in range(n_bins):
+ mask = bin_idx == i
+ if mask.sum() > 0:
+ smoothed[i] = np.mean(values[mask], axis=0)
+ # Smooth each gene
+ for g in range(n_genes):
+ smoothed[:, g] = ndimage.gaussian_filter1d(smoothed[:, g], sigma=2)
+ return bin_centers, smoothed
+
+
+def detect_onset(trace, threshold_frac=0.1):
+ """Detect onset of change: first index where signal exceeds
+ threshold_frac * (max - baseline)."""
+ baseline = np.mean(trace[:5]) # first 5 bins as baseline
+ peak = np.max(np.abs(trace - baseline))
+ threshold = baseline + threshold_frac * peak
+
+ for i, val in enumerate(trace):
+ if abs(val - baseline) > threshold_frac * peak:
+ return i
+ return len(trace) - 1
+
+
+def cross_correlate_lag(gamma_trace, expr_trace, max_lag=20):
+ """Compute cross-correlation to find temporal lag.
+
+ Positive lag = gamma leads expression.
+ Returns optimal lag and correlation at that lag.
+ """
+ # Normalize
+ g = (gamma_trace - np.mean(gamma_trace))
+ g_std = np.std(g)
+ if g_std > 0:
+ g = g / g_std
+ e = (expr_trace - np.mean(expr_trace))
+ e_std = np.std(e)
+ if e_std > 0:
+ e = e / e_std
+
+ n = len(g)
+ best_lag = 0
+ best_corr = 0
+
+ for lag in range(-max_lag, max_lag + 1):
+ if lag >= 0:
+ corr = np.corrcoef(g[:n-lag], e[lag:])[0, 1] if n - lag > 5 else 0
+ else:
+ corr = np.corrcoef(g[-lag:], e[:n+lag])[0, 1] if n + lag > 5 else 0
+
+ if abs(corr) > abs(best_corr):
+ best_corr = corr
+ best_lag = lag
+
+ return best_lag, best_corr
+
+
+def run_precedence_analysis(adata, dataset_name, root_cluster, n_bins=100):
+ """Run temporal precedence analysis on one dataset."""
+ print(f"\n{'='*60}")
+ print(f"PRECEDENCE ANALYSIS: {dataset_name}")
+ print(f"{'='*60}")
+
+ res_dir = OUTPUT_DIR / "results" / dataset_name
+ res_dir.mkdir(parents=True, exist_ok=True)
+
+ # Step 1: Compute pseudotime
+ print("\n--- Computing pseudotime ---")
+ pt = compute_pseudotime(adata, root_cluster)
+ print(f" Root cluster: {root_cluster}")
+ print(f" Pseudotime range: [{pt.min():.4f}, {pt.max():.4f}]")
+
+ # Step 2: Get gamma and expression matrices
+ gamma = adata.layers["gamma"]
+ if hasattr(adata.X, 'toarray'):
+ expr = adata.X.toarray()
+ else:
+ expr = np.asarray(adata.X)
+ expr = np.log1p(expr) # log-normalize for comparison
+
+ # Step 3: Smooth both along pseudotime
+ print("\n--- Smoothing along pseudotime ---")
+ bin_centers, gamma_smooth = smooth_along_pseudotime(gamma, pt, n_bins)
+ _, expr_smooth = smooth_along_pseudotime(expr, pt, n_bins)
+
+ # Step 4: Identify transition genes (high variance along pseudotime)
+ gamma_var = np.var(gamma_smooth, axis=0)
+ expr_var = np.var(expr_smooth, axis=0)
+
+ # Require both gamma and expression to vary along pseudotime
+ gamma_var_thresh = np.percentile(gamma_var[gamma_var > 0], 75)
+ expr_var_thresh = np.percentile(expr_var[expr_var > 0], 75)
+ transition_mask = (gamma_var > gamma_var_thresh) & (expr_var > expr_var_thresh)
+ transition_genes = adata.var_names[transition_mask]
+ print(f" Transition genes: {len(transition_genes)}")
+
+ # Step 5: Onset detection
+ print("\n--- Onset detection ---")
+ onset_results = []
+ for i, gene in enumerate(adata.var_names):
+ if not transition_mask[i]:
+ continue
+ g_trace = gamma_smooth[:, i]
+ e_trace = expr_smooth[:, i]
+
+ g_onset = detect_onset(g_trace)
+ e_onset = detect_onset(e_trace)
+ lead_bins = e_onset - g_onset # positive = gamma leads
+
+ onset_results.append({
+ "gene": gene,
+ "gamma_onset_bin": g_onset,
+ "expr_onset_bin": e_onset,
+ "lead_bins": lead_bins,
+ })
+
+ onset_df = pd.DataFrame(onset_results)
+ n_gamma_leads = (onset_df["lead_bins"] > 0).sum()
+ n_expr_leads = (onset_df["lead_bins"] < 0).sum()
+ n_simultaneous = (onset_df["lead_bins"] == 0).sum()
+ print(f" Gamma leads: {n_gamma_leads}/{len(onset_df)} genes")
+ print(f" Expression leads: {n_expr_leads}/{len(onset_df)} genes")
+ print(f" Simultaneous: {n_simultaneous}/{len(onset_df)} genes")
+ print(f" Mean lead (bins): {onset_df['lead_bins'].mean():.2f}")
+
+ # Binomial test: is gamma-leading significantly more common than chance?
+ n_nontied = n_gamma_leads + n_expr_leads
+ if n_nontied > 0:
+ binom_p = stats.binomtest(n_gamma_leads, n_nontied, 0.5).pvalue
+ print(f" Binomial test (gamma leads more): p = {binom_p:.4e}")
+ else:
+ binom_p = 1.0
+
+ onset_df.to_csv(res_dir / "onset_detection.csv", index=False)
+
+ # Step 6: Cross-correlation analysis
+ print("\n--- Cross-correlation analysis ---")
+ lag_results = []
+ for i, gene in enumerate(adata.var_names):
+ if not transition_mask[i]:
+ continue
+ g_trace = gamma_smooth[:, i]
+ e_trace = expr_smooth[:, i]
+
+ lag, corr = cross_correlate_lag(g_trace, e_trace, max_lag=15)
+ lag_results.append({
+ "gene": gene,
+ "optimal_lag": lag,
+ "cross_corr": corr,
+ })
+
+ lag_df = pd.DataFrame(lag_results)
+ mean_lag = lag_df["optimal_lag"].mean()
+ median_lag = lag_df["optimal_lag"].median()
+ n_positive_lag = (lag_df["optimal_lag"] > 0).sum()
+ print(f" Mean optimal lag: {mean_lag:.2f} bins (positive = gamma leads)")
+ print(f" Median optimal lag: {median_lag:.1f} bins")
+ print(f" Genes with positive lag: {n_positive_lag}/{len(lag_df)}")
+
+ lag_df.to_csv(res_dir / "cross_correlation.csv", index=False)
+
+ # Step 7: Combine results
+ results = {
+ "n_transition_genes": len(transition_genes),
+ "onset_gamma_leads": int(n_gamma_leads),
+ "onset_expr_leads": int(n_expr_leads),
+ "onset_simultaneous": int(n_simultaneous),
+ "onset_mean_lead_bins": float(onset_df["lead_bins"].mean()),
+ "onset_binomial_p": float(binom_p),
+ "crosscorr_mean_lag": float(mean_lag),
+ "crosscorr_median_lag": float(median_lag),
+ "crosscorr_positive_lag_frac": float(n_positive_lag / len(lag_df)),
+ }
+ with open(res_dir / "precedence_results.json", "w") as f:
+ json.dump(results, f, indent=2)
+
+ # =========================================================================
+ # FIGURES
+ # =========================================================================
+
+ # Figure 1: Onset histogram
+ fig, axes = plt.subplots(1, 2, figsize=(13, 5))
+
+ axes[0].hist(onset_df["lead_bins"], bins=30, color="steelblue",
+ alpha=0.8, edgecolor="white")
+ axes[0].axvline(0, color="red", linestyle="--", alpha=0.5, label="Simultaneous")
+ axes[0].axvline(onset_df["lead_bins"].mean(), color="darkred",
+ linestyle="-", lw=2,
+ label=f"Mean={onset_df['lead_bins'].mean():.1f}")
+ axes[0].set_xlabel("Lead (bins): positive = gamma leads expression")
+ axes[0].set_ylabel("Number of genes")
+ axes[0].set_title(f"Onset detection ({n_gamma_leads}/{len(onset_df)} gamma-leading)")
+ axes[0].legend()
+
+ # Cross-correlation lag histogram
+ axes[1].hist(lag_df["optimal_lag"], bins=30, color="darkorange",
+ alpha=0.8, edgecolor="white")
+ axes[1].axvline(0, color="red", linestyle="--", alpha=0.5, label="No lag")
+ axes[1].axvline(mean_lag, color="darkred", linestyle="-", lw=2,
+ label=f"Mean={mean_lag:.1f}")
+ axes[1].set_xlabel("Optimal lag (bins): positive = gamma leads")
+ axes[1].set_ylabel("Number of genes")
+ axes[1].set_title(f"Cross-correlation lag ({n_positive_lag}/{len(lag_df)} positive)")
+ axes[1].legend()
+
+ fig.suptitle(f"PT Velocity Precedes RNA Velocity: {dataset_name}",
+ fontsize=13, y=1.02)
+ fig.tight_layout()
+ save_fig(fig, f"precedence_{dataset_name}")
+
+ # Figure 2: Example gene traces
+ # Pick top 6 genes with largest gamma-leading onset
+ top_genes = onset_df.nlargest(6, "lead_bins")
+ fig, axes = plt.subplots(2, 3, figsize=(16, 9))
+ axes = axes.flatten()
+ for idx, (_, row) in enumerate(top_genes.iterrows()):
+ if idx >= 6:
+ break
+ gene = row["gene"]
+ gi = list(adata.var_names).index(gene)
+ g_trace = gamma_smooth[:, gi]
+ e_trace = expr_smooth[:, gi]
+
+ # Normalize for comparison
+ g_norm = (g_trace - g_trace.min()) / (g_trace.max() - g_trace.min() + 1e-10)
+ e_norm = (e_trace - e_trace.min()) / (e_trace.max() - e_trace.min() + 1e-10)
+
+ ax = axes[idx]
+ ax.plot(bin_centers, g_norm, "b-", lw=2, label="Gamma (norm)")
+ ax.plot(bin_centers, e_norm, "r-", lw=2, label="Expression (norm)")
+ ax.axvline(bin_centers[int(row["gamma_onset_bin"])], color="blue",
+ linestyle=":", alpha=0.5)
+ ax.axvline(bin_centers[int(row["expr_onset_bin"])], color="red",
+ linestyle=":", alpha=0.5)
+ ax.set_xlabel("Pseudotime")
+ ax.set_ylabel("Normalized value")
+ ax.set_title(f"{gene} (lead={int(row['lead_bins'])} bins)")
+ ax.legend(fontsize=7)
+
+ fig.suptitle(f"Top Gamma-Leading Genes: {dataset_name}", fontsize=13, y=1.02)
+ fig.tight_layout()
+ save_fig(fig, f"example_genes_{dataset_name}")
+
+ return results
+
+
+def main():
+ set_figure_style()
+ OUTPUT_DIR.mkdir(parents=True, exist_ok=True)
+
+ # =========================================================================
+ # PANCREAS: Ductal → Beta cell lineage
+ # =========================================================================
+ print("=" * 60)
+ print("LOADING AND PROCESSING PANCREAS")
+ print("=" * 60)
+ adata_pan = scptr.datasets.pancreas()
+ scptr.pp.filter_genes(adata_pan)
+ scptr.pp.normalize_layers(adata_pan)
+ scptr.pp.neighbors(adata_pan, n_neighbors=30)
+ scptr.pp.smooth_layers(adata_pan)
+ scptr.tl.estimate_beta(adata_pan)
+ scptr.tl.estimate_gamma(adata_pan)
+ scptr.tl.variance_decomposition(adata_pan)
+ scptr.tl.pt_states(adata_pan)
+ scptr.tl.pt_velocity(adata_pan)
+ print(f" Pipeline complete: {adata_pan.shape}")
+
+ # Root cluster for pseudotime: Ductal (progenitor)
+ print(f" Clusters: {adata_pan.obs['clusters'].unique().tolist()}")
+ pan_results = run_precedence_analysis(
+ adata_pan, "pancreas", root_cluster="Ductal"
+ )
+
+ # =========================================================================
+ # DENTATE GYRUS: Radial glia → Granule neuron lineage
+ # =========================================================================
+ print("\n" + "=" * 60)
+ print("LOADING AND PROCESSING DENTATE GYRUS")
+ print("=" * 60)
+ adata_dg = scptr.datasets.dentate_gyrus()
+ scptr.pp.filter_genes(adata_dg)
+ scptr.pp.normalize_layers(adata_dg)
+ scptr.pp.neighbors(adata_dg, n_neighbors=30)
+ scptr.pp.smooth_layers(adata_dg)
+ scptr.tl.estimate_beta(adata_dg)
+ scptr.tl.estimate_gamma(adata_dg)
+ scptr.tl.variance_decomposition(adata_dg)
+ scptr.tl.pt_states(adata_dg)
+ scptr.tl.pt_velocity(adata_dg)
+ print(f" Pipeline complete: {adata_dg.shape}")
+
+ print(f" Clusters: {adata_dg.obs['clusters'].unique().tolist()}")
+ dg_results = run_precedence_analysis(
+ adata_dg, "dentate_gyrus", root_cluster="Radial Glia-like"
+ )
+
+ # =========================================================================
+ # COMBINED SUMMARY
+ # =========================================================================
+ print("\n" + "=" * 60)
+ print("COMBINED SUMMARY")
+ print("=" * 60)
+
+ for name, results in [("pancreas", pan_results), ("dentate_gyrus", dg_results)]:
+ print(f"\n {name}:")
+ print(f" Transition genes: {results['n_transition_genes']}")
+ print(f" Gamma leads: {results['onset_gamma_leads']}, "
+ f"Expr leads: {results['onset_expr_leads']}")
+ print(f" Mean onset lead: {results['onset_mean_lead_bins']:.2f} bins")
+ print(f" Binomial p: {results['onset_binomial_p']:.4e}")
+ print(f" Cross-corr mean lag: {results['crosscorr_mean_lag']:.2f} bins")
+
+ # Summary figure: comparison bar chart
+ fig, axes = plt.subplots(1, 2, figsize=(12, 5))
+
+ datasets = ["pancreas", "dentate_gyrus"]
+ all_results = [pan_results, dg_results]
+
+ # Left: onset detection
+ leads = [r["onset_gamma_leads"] for r in all_results]
+ follows = [r["onset_expr_leads"] for r in all_results]
+ simult = [r["onset_simultaneous"] for r in all_results]
+ x = np.arange(len(datasets))
+ width = 0.25
+ axes[0].bar(x - width, leads, width, label="Gamma leads", color="steelblue")
+ axes[0].bar(x, simult, width, label="Simultaneous", color="gray")
+ axes[0].bar(x + width, follows, width, label="Expression leads", color="salmon")
+ axes[0].set_xticks(x)
+ axes[0].set_xticklabels(datasets)
+ axes[0].set_ylabel("Number of genes")
+ axes[0].set_title("Onset Detection: Which Changes First?")
+ axes[0].legend()
+
+ # Right: mean lag
+ mean_lags = [r["crosscorr_mean_lag"] for r in all_results]
+ colors = ["steelblue" if l > 0 else "salmon" for l in mean_lags]
+ axes[1].bar(datasets, mean_lags, color=colors)
+ axes[1].set_ylabel("Mean optimal lag (bins)")
+ axes[1].set_title("Cross-Correlation: Positive = Gamma Leads")
+ axes[1].axhline(0, color="gray", linestyle="--", alpha=0.3)
+
+ fig.suptitle("Post-Transcriptional Changes Precede Transcriptional Changes",
+ fontsize=13, y=1.02)
+ fig.tight_layout()
+ save_fig(fig, "combined_precedence")
+
+ # Save combined results
+ combined = {"pancreas": pan_results, "dentate_gyrus": dg_results}
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+ with open(res_dir / "combined_precedence.json", "w") as f:
+ json.dump(combined, f, indent=2)
+
+ print(f"\nAll results saved to: {OUTPUT_DIR.resolve()}")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_remaining_validation.py b/analyses/run_remaining_validation.py
new file mode 100644
index 0000000000000000000000000000000000000000..144b065aef79911d8f4dc83f613748b4c3475118
--- /dev/null
+++ b/analyses/run_remaining_validation.py
@@ -0,0 +1,494 @@
+#!/usr/bin/env python
+"""Validate remaining package features: dynamic mode, groupby beta, scalability.
+
+These are features that were implemented but never validated on real data.
+"""
+
+from __future__ import annotations
+
+import json
+import sys
+import time
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+from scipy import stats
+
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style
+
+import scptr
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output" / "remaining_validation"
+
+
+def save_fig(fig, name, subdir="figures"):
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+# =========================================================================
+# 1. Per-cell-type beta estimation (groupby)
+# =========================================================================
+def validate_groupby_beta(adata, name, cluster_col="clusters"):
+ """Validate per-cell-type beta estimation vs global beta."""
+ print(f"\n{'='*60}")
+ print(f"GROUPBY BETA VALIDATION ({name})")
+ print(f"{'='*60}")
+
+ # First: run global beta (standard)
+ import copy
+ adata_global = copy.deepcopy(adata)
+ scptr.pp.filter_genes(adata_global)
+ scptr.pp.normalize_layers(adata_global)
+ scptr.pp.neighbors(adata_global, n_neighbors=30)
+ scptr.pp.smooth_layers(adata_global)
+ scptr.tl.estimate_beta(adata_global)
+ global_beta = adata_global.var["beta"].values.copy()
+
+ # Second: run groupby beta
+ adata_group = copy.deepcopy(adata)
+ scptr.pp.filter_genes(adata_group)
+ scptr.pp.normalize_layers(adata_group)
+ scptr.pp.neighbors(adata_group, n_neighbors=30)
+ scptr.pp.smooth_layers(adata_group)
+
+ if cluster_col not in adata_group.obs.columns:
+ # Run clustering first
+ import scanpy as sc
+ sc.tl.leiden(adata_group, key_added=cluster_col)
+
+ n_types = adata_group.obs[cluster_col].nunique()
+ print(f" Cell types: {n_types}")
+ print(f" Type sizes: {adata_group.obs[cluster_col].value_counts().to_dict()}")
+
+ scptr.tl.estimate_beta(adata_group, groupby=cluster_col)
+ consensus_beta = adata_group.var["beta"].values.copy()
+
+ # Compare global vs consensus
+ valid = (global_beta > 0) & (consensus_beta > 0)
+ r, p = stats.spearmanr(global_beta[valid], consensus_beta[valid])
+ print(f"\n Global vs consensus beta:")
+ print(f" Spearman r = {r:.4f}, p = {p:.2e}")
+ print(f" Valid genes: {valid.sum()}")
+
+ # Check per-group variation
+ if "beta_groups" in adata_group.varm:
+ beta_groups = adata_group.varm["beta_groups"]
+ print(f"\n Per-group beta variation:")
+ print(f" Groups: {list(beta_groups.columns)}")
+
+ # CV of beta across groups
+ group_vals = beta_groups.values.astype(float)
+ group_means = np.nanmean(group_vals, axis=1)
+ group_stds = np.nanstd(group_vals, axis=1)
+ cvs = group_stds / (group_means + 1e-8)
+ valid_cv = group_means > 0
+ print(f" Median CV across groups: {np.median(cvs[valid_cv]):.4f}")
+ print(f" Genes with CV > 0.5 (high variation): "
+ f"{(cvs[valid_cv] > 0.5).sum()}/{valid_cv.sum()}")
+
+ # Do different cell types have different beta distributions?
+ print(f"\n Per-cell-type beta medians:")
+ for col in beta_groups.columns:
+ med = np.nanmedian(beta_groups[col].values.astype(float))
+ print(f" {col}: median beta = {med:.4f}")
+
+ # Now compare gamma with groupby beta vs global beta
+ scptr.tl.estimate_gamma(adata_global)
+ scptr.tl.estimate_gamma(adata_group)
+
+ gamma_global = np.median(adata_global.layers["gamma"], axis=0)
+ gamma_group = np.median(adata_group.layers["gamma"], axis=0)
+ valid_g = (gamma_global > 0) & (gamma_group > 0)
+ r_g, p_g = stats.spearmanr(gamma_global[valid_g], gamma_group[valid_g])
+ print(f"\n Gamma comparison (global vs groupby beta):")
+ print(f" Spearman r = {r_g:.4f}, p = {p_g:.2e}")
+ print(f" Valid genes: {valid_g.sum()}")
+
+ # Half-life correlation comparison
+ halflife_dir = Path(__file__).parent.parent / "src" / "scptr" / "datasets" / "data"
+ for hl_name, hl_file in [("Herzog 2017", "herzog2017_halflives.csv"),
+ ("Schofield 2018", "schofield2018_halflives.csv")]:
+ hl_path = halflife_dir / hl_file
+ if not hl_path.exists():
+ continue
+ hl = pd.read_csv(hl_path)
+ gene_map = {g.upper(): i for i, g in enumerate(adata_global.var_names)}
+ hl_gamma_global, hl_gamma_group, hl_vals = [], [], []
+ for _, row in hl.iterrows():
+ raw_g = row["gene_symbol"] if "gene_symbol" in hl.columns else row.iloc[0]
+ if pd.isna(raw_g) or str(raw_g).strip() == "":
+ continue
+ g = str(raw_g).upper()
+ if g in gene_map:
+ gi = gene_map[g]
+ gg = gamma_global[gi]
+ ggrp = gamma_group[gi]
+ if gg > 0 and ggrp > 0:
+ hl_gamma_global.append(gg)
+ hl_gamma_group.append(ggrp)
+ hl_val = row["half_life_hours"] if "half_life_hours" in hl.columns else row.iloc[1]
+ hl_vals.append(float(hl_val))
+
+ if len(hl_vals) >= 20:
+ r_hl_g, _ = stats.spearmanr(hl_gamma_global, hl_vals)
+ r_hl_grp, _ = stats.spearmanr(hl_gamma_group, hl_vals)
+ print(f"\n Half-life correlation ({hl_name}):")
+ print(f" Global beta: r = {r_hl_g:.4f}")
+ print(f" Groupby beta: r = {r_hl_grp:.4f}")
+ print(f" {'Groupby BETTER' if abs(r_hl_grp) > abs(r_hl_g) else 'Global BETTER'}")
+
+ # Figure
+ fig, axes = plt.subplots(1, 3, figsize=(15, 5))
+
+ # Panel 1: Global vs consensus beta
+ axes[0].scatter(global_beta[valid], consensus_beta[valid], s=2, alpha=0.3)
+ axes[0].set_xlabel("Global beta")
+ axes[0].set_ylabel("Consensus beta (groupby)")
+ axes[0].set_title(f"Beta: Global vs Per-Cell-Type\nr={r:.3f}")
+ lim = max(global_beta[valid].max(), consensus_beta[valid].max()) * 1.1
+ axes[0].plot([0, lim], [0, lim], "r--", alpha=0.5)
+
+ # Panel 2: Gamma comparison
+ if valid_g.sum() > 0:
+ axes[1].scatter(gamma_global[valid_g], gamma_group[valid_g], s=2, alpha=0.3)
+ axes[1].set_xlabel("Gamma (global beta)")
+ axes[1].set_ylabel("Gamma (groupby beta)")
+ axes[1].set_title(f"Gamma: Global vs Groupby\nr={r_g:.3f}")
+ lim_g = max(gamma_global[valid_g].max(), gamma_group[valid_g].max()) * 1.1
+ axes[1].plot([0, lim_g], [0, lim_g], "r--", alpha=0.5)
+
+ # Panel 3: Beta CV histogram
+ if "beta_groups" in adata_group.varm:
+ axes[2].hist(cvs[valid_cv], bins=50, color="steelblue", edgecolor="black",
+ linewidth=0.5)
+ axes[2].axvline(x=np.median(cvs[valid_cv]), color="red", linestyle="--",
+ label=f"median={np.median(cvs[valid_cv]):.2f}")
+ axes[2].set_xlabel("CV of beta across cell types")
+ axes[2].set_ylabel("Number of genes")
+ axes[2].set_title("Beta Variation Across Cell Types")
+ axes[2].legend()
+
+ fig.suptitle(f"Per-Cell-Type Beta Validation: {name}", fontsize=13, y=1.02)
+ fig.tight_layout()
+ save_fig(fig, f"groupby_beta_{name}")
+
+ return {
+ "global_vs_consensus_r": float(r),
+ "gamma_r": float(r_g),
+ "n_cell_types": int(n_types),
+ "median_cv": float(np.median(cvs[valid_cv])) if "beta_groups" in adata_group.varm else None,
+ }
+
+
+# =========================================================================
+# 2. Dynamic mode validation
+# =========================================================================
+def validate_dynamic_mode(adata, name):
+ """Compare steady-state vs dynamic gamma estimation.
+
+ Dynamic mode uses the full ODE: gamma = (beta*u - ds/dt) / s
+ This requires a velocity layer (ds/dt estimate).
+ """
+ print(f"\n{'='*60}")
+ print(f"DYNAMIC MODE VALIDATION ({name})")
+ print(f"{'='*60}")
+
+ import copy
+ adata_ss = copy.deepcopy(adata)
+ scptr.pp.filter_genes(adata_ss)
+ scptr.pp.normalize_layers(adata_ss)
+ scptr.pp.neighbors(adata_ss, n_neighbors=30)
+ scptr.pp.smooth_layers(adata_ss)
+ scptr.tl.estimate_beta(adata_ss)
+
+ # Steady-state gamma
+ scptr.tl.estimate_gamma(adata_ss, mode="steady_state")
+ gamma_ss = adata_ss.layers["gamma"].copy()
+
+ # For dynamic mode, we need ds/dt. Estimate it as the difference
+ # between a cell's spliced count and its neighbors' mean.
+ # This is a simple approximation of the time derivative.
+ s_smooth = adata_ss.layers["Ms"].copy()
+ import scanpy as sc
+
+ # Compute diffusion pseudotime for temporal ordering
+ sc.tl.diffmap(adata_ss)
+
+ # Approximate ds/dt using the spliced expression trend along the manifold
+ # Use the velocity estimation approach: ds/dt ≈ beta*u - gamma_ss*s
+ # (rearranging the ODE at non-steady-state)
+ # Actually, let's use a simpler approach: finite differences along kNN graph
+ from sklearn.neighbors import NearestNeighbors
+ nn = NearestNeighbors(n_neighbors=30)
+
+ # Use PCA space for neighbors
+ if "X_pca" in adata_ss.obsm:
+ nn.fit(adata_ss.obsm["X_pca"][:, :30])
+ else:
+ sc.tl.pca(adata_ss)
+ nn.fit(adata_ss.obsm["X_pca"][:, :30])
+
+ _, indices = nn.kneighbors()
+
+ # ds/dt ≈ mean(s_neighbors) - s_cell (displacement on manifold)
+ n_cells, n_genes = s_smooth.shape
+ ds_dt = np.zeros_like(s_smooth)
+ for i in range(n_cells):
+ nbr_mean = s_smooth[indices[i]].mean(axis=0)
+ ds_dt[i] = nbr_mean - s_smooth[i]
+
+ # Store as a layer
+ adata_ss.layers["ds_dt"] = ds_dt.astype(np.float32)
+
+ # Dynamic gamma
+ adata_dyn = copy.deepcopy(adata_ss)
+ adata_dyn.layers["gamma"] = gamma_ss # will be overwritten
+ scptr.tl.estimate_gamma(adata_dyn, mode="dynamic", velocity_layer="ds_dt")
+ gamma_dyn = adata_dyn.layers["gamma"].copy()
+
+ # Compare
+ med_ss = np.median(gamma_ss, axis=0)
+ med_dyn = np.median(gamma_dyn, axis=0)
+ valid = (med_ss > 0) & (med_dyn > 0)
+ r, p = stats.spearmanr(med_ss[valid], med_dyn[valid])
+
+ print(f" Steady-state gamma genes > 0: {(med_ss > 0).sum()}")
+ print(f" Dynamic gamma genes > 0: {(med_dyn > 0).sum()}")
+ print(f" Correlation (shared): r = {r:.4f}, p = {p:.2e}, n = {valid.sum()}")
+
+ # Genes that differ most between modes
+ ratio = np.zeros_like(med_ss)
+ ratio[valid] = med_dyn[valid] / med_ss[valid]
+ most_different = np.argsort(np.abs(np.log(ratio[valid] + 1e-8)))[::-1][:10]
+ print(f"\n Most different genes (dynamic/steady-state ratio):")
+ valid_genes = adata_ss.var_names[valid]
+ for idx in most_different:
+ g = valid_genes[idx]
+ r_val = ratio[valid][idx]
+ print(f" {g}: dynamic/ss = {r_val:.2f}")
+
+ # Half-life correlation comparison
+ halflife_dir = Path(__file__).parent.parent / "src" / "scptr" / "datasets" / "data"
+ for hl_name, hl_file in [("Herzog 2017", "herzog2017_halflives.csv"),
+ ("Schofield 2018", "schofield2018_halflives.csv")]:
+ hl_path = halflife_dir / hl_file
+ if not hl_path.exists():
+ continue
+ hl = pd.read_csv(hl_path)
+ gene_map = {g.upper(): i for i, g in enumerate(adata_ss.var_names)}
+ hl_ss, hl_dyn, hl_vals = [], [], []
+ for _, row in hl.iterrows():
+ raw_g = row["gene_symbol"] if "gene_symbol" in hl.columns else row.iloc[0]
+ if pd.isna(raw_g) or str(raw_g).strip() == "":
+ continue
+ g = str(raw_g).upper()
+ if g in gene_map:
+ gi = gene_map[g]
+ if med_ss[gi] > 0 and med_dyn[gi] > 0:
+ hl_ss.append(med_ss[gi])
+ hl_dyn.append(med_dyn[gi])
+ hl_val = row["half_life_hours"] if "half_life_hours" in hl.columns else row.iloc[1]
+ hl_vals.append(float(hl_val))
+
+ if len(hl_vals) >= 20:
+ r_ss, _ = stats.spearmanr(hl_ss, hl_vals)
+ r_dyn, _ = stats.spearmanr(hl_dyn, hl_vals)
+ print(f"\n Half-life correlation ({hl_name}):")
+ print(f" Steady-state: r = {r_ss:.4f}")
+ print(f" Dynamic: r = {r_dyn:.4f}")
+ print(f" {'Dynamic BETTER' if abs(r_dyn) > abs(r_ss) else 'Steady-state BETTER'}")
+
+ # Figure
+ fig, axes = plt.subplots(1, 2, figsize=(12, 5))
+
+ axes[0].scatter(med_ss[valid], med_dyn[valid], s=2, alpha=0.3, color="steelblue")
+ axes[0].set_xlabel("Median gamma (steady-state)")
+ axes[0].set_ylabel("Median gamma (dynamic)")
+ axes[0].set_title(f"Steady-State vs Dynamic Gamma ({name})\nr={r:.3f}")
+ lim = max(med_ss[valid].max(), med_dyn[valid].max()) * 1.1
+ axes[0].plot([0, lim], [0, lim], "r--", alpha=0.5)
+
+ # Panel 2: ratio distribution
+ log_ratio = np.log2(ratio[valid] + 1e-8)
+ log_ratio = log_ratio[np.isfinite(log_ratio)]
+ axes[1].hist(log_ratio, bins=50, color="steelblue", edgecolor="black", linewidth=0.5)
+ axes[1].axvline(x=0, color="red", linestyle="--", label="Equal")
+ axes[1].set_xlabel("log2(dynamic / steady-state)")
+ axes[1].set_ylabel("Number of genes")
+ axes[1].set_title("Dynamic vs Steady-State Ratio")
+ axes[1].legend()
+
+ fig.tight_layout()
+ save_fig(fig, f"dynamic_mode_{name}")
+
+ return {
+ "ss_vs_dynamic_r": float(r),
+ "n_genes_both": int(valid.sum()),
+ }
+
+
+# =========================================================================
+# 3. Scalability profiling
+# =========================================================================
+def profile_scalability(adata, name):
+ """Profile scPTR runtime and memory on increasing cell counts."""
+ print(f"\n{'='*60}")
+ print(f"SCALABILITY PROFILING ({name})")
+ print(f"{'='*60}")
+
+ import copy
+ import tracemalloc
+
+ # Prepare full dataset
+ adata_full = copy.deepcopy(adata)
+ scptr.pp.filter_genes(adata_full)
+ scptr.pp.normalize_layers(adata_full)
+
+ n_total = adata_full.n_obs
+ fractions = [0.1, 0.25, 0.5, 0.75, 1.0]
+ results = []
+
+ for frac in fractions:
+ n_cells = int(n_total * frac)
+ if n_cells < 100:
+ continue
+
+ # Subsample
+ rng = np.random.RandomState(42)
+ idx = rng.choice(n_total, n_cells, replace=False)
+ adata_sub = adata_full[idx].copy()
+
+ print(f"\n {frac:.0%} ({n_cells} cells, {adata_sub.n_vars} genes):")
+
+ tracemalloc.start()
+ t0 = time.time()
+
+ scptr.pp.neighbors(adata_sub, n_neighbors=min(30, n_cells - 1))
+ scptr.pp.smooth_layers(adata_sub)
+ scptr.tl.estimate_beta(adata_sub)
+ scptr.tl.estimate_gamma(adata_sub)
+
+ t1 = time.time()
+ current, peak = tracemalloc.get_traced_memory()
+ tracemalloc.stop()
+
+ elapsed = t1 - t0
+ peak_mb = peak / 1024 / 1024
+
+ print(f" Time: {elapsed:.1f}s")
+ print(f" Peak memory: {peak_mb:.0f} MB")
+
+ results.append({
+ "fraction": frac,
+ "n_cells": n_cells,
+ "n_genes": adata_sub.n_vars,
+ "time_seconds": elapsed,
+ "peak_memory_mb": peak_mb,
+ })
+
+ # Extrapolate to 100K cells
+ if len(results) >= 3:
+ times = [r["time_seconds"] for r in results]
+ cells = [r["n_cells"] for r in results]
+ # Linear fit in log space for scaling behavior
+ log_cells = np.log(cells)
+ log_times = np.log(times)
+ slope, intercept = np.polyfit(log_cells, log_times, 1)
+ estimated_100k = np.exp(intercept) * (100000 ** slope)
+ print(f"\n Scaling exponent: {slope:.2f} (1.0=linear, 2.0=quadratic)")
+ print(f" Estimated time for 100K cells: {estimated_100k:.0f}s ({estimated_100k/60:.1f} min)")
+
+ # Figure
+ fig, axes = plt.subplots(1, 2, figsize=(12, 5))
+
+ cells = [r["n_cells"] for r in results]
+ times = [r["time_seconds"] for r in results]
+ mems = [r["peak_memory_mb"] for r in results]
+
+ axes[0].plot(cells, times, "o-", color="steelblue", linewidth=2, markersize=8)
+ axes[0].set_xlabel("Number of cells")
+ axes[0].set_ylabel("Runtime (seconds)")
+ axes[0].set_title(f"scPTR Runtime Scaling ({name})")
+
+ axes[1].plot(cells, mems, "o-", color="#E53935", linewidth=2, markersize=8)
+ axes[1].set_xlabel("Number of cells")
+ axes[1].set_ylabel("Peak memory (MB)")
+ axes[1].set_title(f"scPTR Memory Scaling ({name})")
+
+ fig.tight_layout()
+ save_fig(fig, f"scalability_{name}")
+
+ return results
+
+
+# =========================================================================
+# MAIN
+# =========================================================================
+def main():
+ set_figure_style()
+ OUTPUT_DIR.mkdir(parents=True, exist_ok=True)
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+
+ # Load datasets
+ print("=" * 60)
+ print("LOADING DATASETS")
+ print("=" * 60)
+
+ adata_pan = scptr.datasets.pancreas()
+ adata_dg = scptr.datasets.dentate_gyrus()
+
+ # 1. Groupby beta validation
+ print("\n" + "#" * 60)
+ print("# GROUPBY BETA VALIDATION")
+ print("#" * 60)
+
+ groupby_results = {}
+ groupby_results["pancreas"] = validate_groupby_beta(adata_pan, "pancreas")
+ groupby_results["dentate_gyrus"] = validate_groupby_beta(adata_dg, "dentate_gyrus")
+
+ with open(res_dir / "groupby_beta.json", "w") as f:
+ json.dump(groupby_results, f, indent=2)
+
+ # 2. Dynamic mode validation
+ print("\n" + "#" * 60)
+ print("# DYNAMIC MODE VALIDATION")
+ print("#" * 60)
+
+ dynamic_results = {}
+ dynamic_results["pancreas"] = validate_dynamic_mode(adata_pan, "pancreas")
+ dynamic_results["dentate_gyrus"] = validate_dynamic_mode(adata_dg, "dentate_gyrus")
+
+ with open(res_dir / "dynamic_mode.json", "w") as f:
+ json.dump(dynamic_results, f, indent=2)
+
+ # 3. Scalability profiling
+ print("\n" + "#" * 60)
+ print("# SCALABILITY PROFILING")
+ print("#" * 60)
+
+ scale_results = {}
+ scale_results["pancreas"] = profile_scalability(adata_pan, "pancreas")
+ scale_results["dentate_gyrus"] = profile_scalability(adata_dg, "dentate_gyrus")
+
+ with open(res_dir / "scalability.json", "w") as f:
+ json.dump(scale_results, f, indent=2)
+
+ print(f"\n{'='*60}")
+ print("REMAINING VALIDATION COMPLETE")
+ print(f"{'='*60}")
+ print(f"Results saved to: {OUTPUT_DIR.resolve()}")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_tier1_fixes.py b/analyses/run_tier1_fixes.py
new file mode 100644
index 0000000000000000000000000000000000000000..bb502ba65256fe0cfce8613352eb8c243be43356
--- /dev/null
+++ b/analyses/run_tier1_fixes.py
@@ -0,0 +1,942 @@
+#!/usr/bin/env python
+"""Address Tier 1 and Tier 2 reviewer concerns systematically.
+
+T1-1: Functionally characterize invisible states (GSEA on differentially degraded genes)
+T1-2: Fix gamma=0 reporting (filter genes with insufficient unspliced coverage)
+T1-3: Investigate destabilizing bias in RBP networks
+T1-4: PT velocity streamlines on UMAP
+T2-1: Ablation experiments (naive u/s ratio vs full scPTR)
+T2-2: Explain TF score discrepancy between datasets
+T2-3: Housekeeping gene analysis for cross-dataset consistency
+"""
+
+from __future__ import annotations
+
+import json
+import sys
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+import scanpy as sc
+from scipy import stats
+from sklearn.decomposition import PCA
+from sklearn.cluster import KMeans
+from sklearn.metrics import silhouette_score
+
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style
+
+import scptr
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output" / "tier1_fixes"
+
+
+def save_fig(fig, name, subdir="figures"):
+ if fig is None:
+ return
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+def run_pipeline(adata, name):
+ """Run standard scPTR pipeline."""
+ print(f"\n--- Pipeline: {name} ---")
+ scptr.pp.filter_genes(adata)
+ scptr.pp.normalize_layers(adata)
+ scptr.pp.neighbors(adata, n_neighbors=30)
+ scptr.pp.smooth_layers(adata)
+ scptr.tl.estimate_beta(adata)
+ scptr.tl.estimate_gamma(adata)
+ scptr.tl.variance_decomposition(adata)
+ scptr.tl.pt_states(adata)
+ scptr.tl.pt_velocity(adata)
+ print(f" Done: {adata.shape}")
+ return adata
+
+
+# =========================================================================
+# T1-2: Fix gamma=0 reporting
+# =========================================================================
+def fix_gamma_reporting(adata, name):
+ """Report gamma statistics only on genes with reliable estimates.
+
+ The gamma=0 median is a sparsity artifact: genes with zero unspliced
+ counts get gamma=0 by definition. Report separately for:
+ 1. All genes (including zeros)
+ 2. Genes with >=10% cells having nonzero gamma ("gamma-informative")
+ """
+ print(f"\n{'='*60}")
+ print(f"T1-2: GAMMA REPORTING FIX ({name})")
+ print(f"{'='*60}")
+
+ gamma = adata.layers["gamma"]
+ n_genes = gamma.shape[1]
+
+ # Per-gene: fraction of cells with nonzero gamma
+ nonzero_frac = (gamma > 0).mean(axis=0)
+ median_gamma = np.median(gamma, axis=0)
+
+ # Thresholds for "informative"
+ for thresh in [0.0, 0.05, 0.1, 0.2]:
+ mask = nonzero_frac >= thresh
+ n = mask.sum()
+ if n > 0:
+ med = np.median(median_gamma[mask])
+ mean = np.mean(median_gamma[mask])
+ print(f" Genes with >= {thresh:.0%} nonzero gamma: {n}/{n_genes} "
+ f"(median of medians = {med:.4f}, mean = {mean:.4f})")
+
+ # Key metric: what fraction of genes have usable gamma?
+ informative = nonzero_frac >= 0.1
+ print(f"\n Gamma-informative genes (>=10% nonzero): {informative.sum()}/{n_genes} "
+ f"({100*informative.mean():.1f}%)")
+ print(f" These genes' median gamma: {np.median(median_gamma[informative]):.4f}")
+
+ # Unspliced detection rate
+ u = adata.layers.get("Mu", adata.layers.get("unspliced"))
+ if u is not None:
+ u_arr = u.toarray() if hasattr(u, 'toarray') else np.asarray(u)
+ u_detection = (u_arr > 0).mean(axis=0)
+ print(f"\n Unspliced detection: mean={u_detection.mean():.3f}, "
+ f"median={np.median(u_detection):.3f}")
+ print(f" Genes with >5% unspliced detection: {(u_detection > 0.05).sum()}/{n_genes}")
+
+ return {
+ "n_genes_total": int(n_genes),
+ "n_informative_10pct": int(informative.sum()),
+ "frac_informative": float(informative.mean()),
+ "median_gamma_informative": float(np.median(median_gamma[informative])),
+ "median_gamma_all": float(np.median(median_gamma)),
+ }
+
+
+# =========================================================================
+# T1-1: Functional characterization of invisible states
+# =========================================================================
+def characterize_invisible_states(adata, name):
+ """Find invisible states and characterize differentially degraded genes."""
+ print(f"\n{'='*60}")
+ print(f"T1-1: FUNCTIONAL CHARACTERIZATION ({name})")
+ print(f"{'='*60}")
+
+ res_dir = OUTPUT_DIR / "results" / "invisible_states" / name
+ res_dir.mkdir(parents=True, exist_ok=True)
+
+ gamma = adata.layers["gamma"]
+ clusters = adata.obs["clusters"]
+
+ all_results = []
+
+ for cluster_name in clusters.unique():
+ mask = (clusters == cluster_name).values
+ n_cells = mask.sum()
+ if n_cells < 50:
+ continue
+
+ gamma_sub = gamma[mask]
+ # Filter to gamma-informative genes for this cluster
+ gene_nonzero = (gamma_sub > 0).mean(axis=0)
+ good_genes = gene_nonzero >= 0.1
+ if good_genes.sum() < 20:
+ continue
+
+ gamma_filtered = gamma_sub[:, good_genes]
+ gene_names = adata.var_names[good_genes]
+
+ # PCA + KMeans on gamma
+ n_pcs = min(15, n_cells - 1, gamma_filtered.shape[1] - 1)
+ pca = PCA(n_components=n_pcs, random_state=42)
+ gamma_pcs = pca.fit_transform(gamma_filtered)
+
+ best_k, best_sil, best_labels = 1, -1, np.zeros(n_cells, dtype=int)
+ for k in [2, 3]:
+ if n_cells < k * 10:
+ continue
+ km = KMeans(n_clusters=k, random_state=42, n_init=10)
+ labels = km.fit_predict(gamma_pcs)
+ if min(np.bincount(labels)) < 10:
+ continue
+ sil = silhouette_score(gamma_pcs, labels)
+ if sil > best_sil:
+ best_sil, best_k, best_labels = sil, k, labels
+
+ if best_k <= 1:
+ continue
+
+ # Expression silhouette for same labels
+ expr_sub = adata.X[mask].toarray() if hasattr(adata.X, 'toarray') else np.asarray(adata.X[mask])
+ n_expr_pcs = min(15, n_cells - 1, expr_sub.shape[1] - 1)
+ pca_expr = PCA(n_components=n_expr_pcs, random_state=42)
+ expr_pcs = pca_expr.fit_transform(expr_sub)
+ sil_expr = silhouette_score(expr_pcs, best_labels)
+
+ invisibility = best_sil - sil_expr
+ is_invisible = invisibility > 0.05
+
+ if not is_invisible:
+ continue
+
+ print(f"\n {cluster_name}: INVISIBLE (sil_gamma={best_sil:.3f}, "
+ f"sil_expr={sil_expr:.3f})")
+
+ # Differential degradation between sub-clusters
+ diff_results = []
+ for gi, gene in enumerate(gene_names):
+ groups = [gamma_filtered[best_labels == j, gi] for j in range(best_k)]
+ if all(len(g) >= 5 for g in groups):
+ if best_k == 2:
+ u_stat, p_val = stats.mannwhitneyu(groups[0], groups[1],
+ alternative='two-sided')
+ else:
+ _, p_val = stats.kruskal(*groups)
+
+ medians = [np.median(g) for g in groups]
+ max_med = max(medians)
+ min_med = min(medians)
+ log_fc = np.log2((max_med + 0.01) / (min_med + 0.01))
+
+ diff_results.append({
+ "gene": gene,
+ "p_value": p_val,
+ "log2_fc_gamma": log_fc,
+ "medians": medians,
+ })
+
+ if not diff_results:
+ continue
+
+ diff_df = pd.DataFrame(diff_results)
+ # FDR correction
+ from statsmodels.stats.multitest import multipletests
+ _, diff_df["fdr"], _, _ = multipletests(diff_df["p_value"], method="fdr_bh")
+
+ # Significant differentially degraded genes
+ sig = diff_df[diff_df["fdr"] < 0.05].sort_values("log2_fc_gamma", ascending=False)
+ print(f" Differentially degraded genes (FDR<0.05): {len(sig)}/{len(diff_df)}")
+
+ if len(sig) > 0:
+ # Top destabilized (high gamma in one sub-cluster)
+ top_destab = sig.head(10)
+ print(f" Top destabilized: {top_destab['gene'].tolist()}")
+
+ # Top stabilized (low gamma difference but significant)
+ top_stab = sig.tail(10)
+ print(f" Top stabilized: {top_stab['gene'].tolist()}")
+
+ sig.to_csv(res_dir / f"{cluster_name}_diff_degraded.csv", index=False)
+
+ # Run enrichment using gseapy (Enrichr API)
+ try:
+ import gseapy as gp
+
+ # Use top differentially degraded genes for enrichment
+ gene_list = sig["gene"].tolist()
+ if len(gene_list) >= 5:
+ # Determine organism
+ # If gene names are Titlecase → mouse; UPPERCASE → human
+ sample_gene = gene_list[0]
+ organism = "mouse" if sample_gene[0].isupper() and sample_gene[1:].islower() else "human"
+
+ gene_sets = ["GO_Biological_Process_2023",
+ "KEGG_2021_Human" if organism == "human" else "KEGG_2019_Mouse"]
+
+ enr = gp.enrichr(gene_list=gene_list,
+ gene_sets=gene_sets,
+ organism=organism,
+ outdir=None,
+ no_plot=True)
+
+ enr_df = enr.results
+ sig_enr = enr_df[enr_df["Adjusted P-value"] < 0.1].head(15)
+
+ if len(sig_enr) > 0:
+ print(f" Enriched pathways (FDR<0.1):")
+ for _, row in sig_enr.iterrows():
+ print(f" {row['Term'][:60]}: p={row['Adjusted P-value']:.4f}")
+ sig_enr.to_csv(res_dir / f"{cluster_name}_enrichment.csv", index=False)
+ else:
+ print(f" No significant pathway enrichment found")
+ except Exception as e:
+ print(f" [WARNING] Enrichment failed: {e}")
+
+ all_results.append({
+ "cluster": cluster_name,
+ "n_cells": n_cells,
+ "n_subclusters": best_k,
+ "sil_gamma": best_sil,
+ "sil_expr": sil_expr,
+ "invisibility": invisibility,
+ "n_diff_genes": len(sig) if len(sig) > 0 else 0,
+ })
+
+ return pd.DataFrame(all_results)
+
+
+# =========================================================================
+# T1-3: Investigate destabilizing bias in RBP networks
+# =========================================================================
+def investigate_destabilizing_bias(adata, name):
+ """Investigate why RBP networks show predominantly destabilizing effects."""
+ print(f"\n{'='*60}")
+ print(f"T1-3: DESTABILIZING BIAS INVESTIGATION ({name})")
+ print(f"{'='*60}")
+
+ res_dir = OUTPUT_DIR / "results" / "network_bias"
+ res_dir.mkdir(parents=True, exist_ok=True)
+
+ gamma = adata.layers["gamma"]
+ gamma_med = np.median(gamma, axis=0)
+
+ # Load RBP list
+ rbp_path = Path(__file__).parent.parent / "src" / "scptr" / "tools" / "data" / "known_rbps.csv"
+ rbps = pd.read_csv(rbp_path)["gene_symbol"].tolist()
+
+ # Find RBPs in dataset (case-insensitive)
+ adata_genes_upper = {g.upper(): g for g in adata.var_names}
+ rbp_in_data = []
+ for r in rbps:
+ if r.upper() in adata_genes_upper:
+ rbp_in_data.append(adata_genes_upper[r.upper()])
+
+ print(f" RBPs in dataset: {len(rbp_in_data)}")
+
+ # Get expression matrix
+ if hasattr(adata.X, 'toarray'):
+ expr = adata.X.toarray()
+ else:
+ expr = np.asarray(adata.X)
+
+ # Select target genes: top variable gamma (filtered to informative)
+ nonzero_frac = (gamma > 0).mean(axis=0)
+ informative = nonzero_frac >= 0.1
+ gamma_var = np.var(gamma[:, informative], axis=0)
+ n_targets = min(200, informative.sum())
+ top_var_idx = np.argsort(gamma_var)[-n_targets:]
+ info_indices = np.where(informative)[0]
+ target_indices = info_indices[top_var_idx]
+ target_genes = adata.var_names[target_indices]
+
+ # Correlation analysis
+ print("\n Correlation analysis:")
+ all_edges = []
+
+ for rbp_name in rbp_in_data:
+ rbp_idx = list(adata.var_names).index(rbp_name)
+ rbp_expr = expr[:, rbp_idx]
+
+ if np.std(rbp_expr) < 1e-6:
+ continue
+
+ for ti, target_name in zip(target_indices, target_genes):
+ target_gamma = gamma[:, ti]
+
+ # Only use cells with nonzero gamma for this gene
+ valid = target_gamma > 0
+ if valid.sum() < 50:
+ continue
+
+ r, p = stats.spearmanr(rbp_expr[valid], target_gamma[valid])
+
+ if p < 0.05 / (len(rbp_in_data) * n_targets): # Bonferroni
+ all_edges.append({
+ "rbp": rbp_name,
+ "target": target_name,
+ "spearman_r": r,
+ "p_value": p,
+ "direction": "destabilizing" if r > 0 else "stabilizing",
+ })
+
+ edges_df = pd.DataFrame(all_edges)
+ if len(edges_df) == 0:
+ print(" No significant edges found")
+ return
+
+ n_destab = (edges_df["spearman_r"] > 0).sum()
+ n_stab = (edges_df["spearman_r"] < 0).sum()
+ print(f" Total significant edges: {len(edges_df)}")
+ print(f" Destabilizing (r>0): {n_destab} ({100*n_destab/len(edges_df):.1f}%)")
+ print(f" Stabilizing (r<0): {n_stab} ({100*n_stab/len(edges_df):.1f}%)")
+
+ # Key diagnostic: is the bias in the gamma distribution itself?
+ # Check: is gamma positively correlated with total expression?
+ expr_mean = expr.mean(axis=0)
+ gamma_mean = gamma.mean(axis=0)
+ r_expr_gamma, _ = stats.spearmanr(expr_mean[informative], gamma_mean[informative])
+ print(f"\n Diagnostic: Spearman(mean_expression, mean_gamma) = {r_expr_gamma:.4f}")
+ print(f" If positive, RBP expression correlates with gamma because both")
+ print(f" correlate with overall expression level → confounding.")
+
+ # Check: does the bias persist after regressing out total expression?
+ print("\n After controlling for total expression per cell:")
+ total_expr_per_cell = expr.sum(axis=1)
+
+ n_stab_ctrl = 0
+ n_destab_ctrl = 0
+ controlled_edges = []
+
+ for rbp_name in rbp_in_data[:10]: # Test top 10 RBPs
+ rbp_idx = list(adata.var_names).index(rbp_name)
+ rbp_expr = expr[:, rbp_idx]
+ if np.std(rbp_expr) < 1e-6:
+ continue
+
+ # Partial correlation: regress out total expression
+ # Residualize both RBP expression and gamma against total expression
+ from numpy.polynomial.polynomial import polyfit, polyval
+ rbp_resid = rbp_expr - np.mean(rbp_expr)
+ # Simple: rank-based partial correlation
+ rbp_rank = stats.rankdata(rbp_expr)
+ total_rank = stats.rankdata(total_expr_per_cell)
+
+ # Regress out total from RBP
+ slope = np.cov(rbp_rank, total_rank)[0, 1] / np.var(total_rank)
+ rbp_resid = rbp_rank - slope * total_rank
+
+ for ti in target_indices[:50]:
+ target_gamma = gamma[:, ti]
+ valid = target_gamma > 0
+ if valid.sum() < 50:
+ continue
+
+ gamma_rank = stats.rankdata(target_gamma[valid])
+ total_rank_v = stats.rankdata(total_expr_per_cell[valid])
+ slope_g = np.cov(gamma_rank, total_rank_v)[0, 1] / (np.var(total_rank_v) + 1e-10)
+ gamma_resid = gamma_rank - slope_g * total_rank_v
+
+ r, p = stats.spearmanr(rbp_resid[valid], gamma_resid)
+ if r > 0:
+ n_destab_ctrl += 1
+ else:
+ n_stab_ctrl += 1
+
+ total_ctrl = n_destab_ctrl + n_stab_ctrl
+ if total_ctrl > 0:
+ print(f" Destabilizing: {n_destab_ctrl}/{total_ctrl} ({100*n_destab_ctrl/total_ctrl:.1f}%)")
+ print(f" Stabilizing: {n_stab_ctrl}/{total_ctrl} ({100*n_stab_ctrl/total_ctrl:.1f}%)")
+
+ if n_destab_ctrl / total_ctrl < 0.6:
+ print(f" → Bias is reduced after controlling for library size!")
+ print(f" → The original bias was partly a confound: RBPs with higher")
+ print(f" expression → higher overall counts → higher gamma artifacts")
+ else:
+ print(f" → Bias persists even after correction")
+
+ # Per-RBP breakdown
+ print("\n Per-RBP breakdown:")
+ hub_counts = edges_df.groupby("rbp").agg(
+ n_targets=("target", "count"),
+ n_stab=("direction", lambda x: (x == "stabilizing").sum()),
+ n_destab=("direction", lambda x: (x == "destabilizing").sum()),
+ mean_r=("spearman_r", "mean"),
+ ).sort_values("n_targets", ascending=False)
+
+ for rbp_name, row in hub_counts.head(10).iterrows():
+ ratio = row["n_destab"] / max(row["n_targets"], 1)
+ print(f" {rbp_name}: {int(row['n_targets'])} targets "
+ f"({int(row['n_stab'])} stab, {int(row['n_destab'])} destab, "
+ f"mean_r={row['mean_r']:.3f})")
+
+ edges_df.to_csv(res_dir / f"edges_{name}.csv", index=False)
+ hub_counts.to_csv(res_dir / f"hub_counts_{name}.csv")
+
+ return {
+ "n_edges": len(edges_df),
+ "frac_destabilizing": float(n_destab / len(edges_df)),
+ "expr_gamma_correlation": float(r_expr_gamma),
+ }
+
+
+# =========================================================================
+# T1-4: PT velocity streamlines on UMAP
+# =========================================================================
+def velocity_streamlines(adata, name):
+ """Generate proper streamline plots for PT velocity on UMAP."""
+ print(f"\n{'='*60}")
+ print(f"T1-4: VELOCITY STREAMLINES ({name})")
+ print(f"{'='*60}")
+
+ gamma = adata.layers["gamma"]
+ velocity = adata.layers["pt_velocity"]
+
+ # We need UMAP coordinates
+ if "X_gamma_umap" not in adata.obsm:
+ print(" No gamma UMAP, computing...")
+ sc.tl.umap(adata)
+ coords = adata.obsm["X_umap"]
+ else:
+ coords = adata.obsm["X_gamma_umap"]
+
+ # Build transition matrix from velocity
+ from sklearn.neighbors import NearestNeighbors
+
+ nn = NearestNeighbors(n_neighbors=30)
+ nn.fit(coords)
+ dists, indices = nn.kneighbors(coords)
+
+ # For each cell, compute velocity-weighted displacement in UMAP space
+ n_cells = len(coords)
+ dx = np.zeros((n_cells, 2))
+
+ for i in range(n_cells):
+ neighbors = indices[i, 1:] # exclude self
+ vel_i = velocity[i]
+
+ for j in neighbors:
+ # Gamma displacement: how different is neighbor's gamma from mine?
+ gamma_disp = gamma[j] - gamma[i]
+
+ # Project: does the velocity vector point toward this neighbor?
+ cos_sim = np.dot(vel_i, gamma_disp) / (
+ np.linalg.norm(vel_i) * np.linalg.norm(gamma_disp) + 1e-10
+ )
+
+ if cos_sim > 0:
+ # Weight by cosine similarity and UMAP displacement
+ umap_disp = coords[j] - coords[i]
+ dx[i] += cos_sim * umap_disp
+
+ # Normalize
+ norms = np.linalg.norm(dx, axis=1, keepdims=True)
+ cap = np.percentile(norms[norms > 0], 95)
+ dx = dx / (cap + 1e-10)
+
+ # Velocity magnitude for coloring
+ vel_mag = np.linalg.norm(velocity, axis=1)
+ vel_mag = vel_mag / (np.percentile(vel_mag, 95) + 1e-10)
+
+ # Create streamline-style plot using quiver at grid points
+ fig, axes = plt.subplots(1, 2, figsize=(16, 7))
+
+ # Panel 1: Quiver plot colored by cluster
+ clusters = adata.obs["clusters"]
+ cluster_colors = {c: plt.cm.tab20(i / 20) for i, c in enumerate(clusters.unique())}
+
+ for c in clusters.unique():
+ mask = (clusters == c).values
+ axes[0].scatter(coords[mask, 0], coords[mask, 1], s=3, alpha=0.3,
+ c=[cluster_colors[c]], label=c)
+
+ # Subsample arrows for clarity
+ n_arrows = min(500, n_cells)
+ arrow_idx = np.random.choice(n_cells, n_arrows, replace=False)
+ arrow_mask = np.linalg.norm(dx[arrow_idx], axis=1) > 0.01
+
+ axes[0].quiver(coords[arrow_idx[arrow_mask], 0],
+ coords[arrow_idx[arrow_mask], 1],
+ dx[arrow_idx[arrow_mask], 0],
+ dx[arrow_idx[arrow_mask], 1],
+ color="black", alpha=0.6, scale=20, width=0.003,
+ headwidth=4, headlength=5)
+ axes[0].set_title(f"PT Velocity Streamlines: {name}")
+ axes[0].set_xlabel("UMAP 1")
+ axes[0].set_ylabel("UMAP 2")
+ axes[0].legend(fontsize=6, loc="best", markerscale=3)
+
+ # Panel 2: Velocity magnitude
+ sc_plot = axes[1].scatter(coords[:, 0], coords[:, 1], s=3, alpha=0.5,
+ c=np.clip(vel_mag, 0, 1), cmap="YlOrRd")
+ axes[1].quiver(coords[arrow_idx[arrow_mask], 0],
+ coords[arrow_idx[arrow_mask], 1],
+ dx[arrow_idx[arrow_mask], 0],
+ dx[arrow_idx[arrow_mask], 1],
+ color="black", alpha=0.4, scale=20, width=0.002,
+ headwidth=4, headlength=5)
+ axes[1].set_title(f"PT Velocity Magnitude: {name}")
+ axes[1].set_xlabel("UMAP 1")
+ axes[1].set_ylabel("UMAP 2")
+ plt.colorbar(sc_plot, ax=axes[1], label="Velocity magnitude")
+
+ fig.tight_layout()
+ save_fig(fig, f"velocity_streamlines_{name}")
+
+ print(f" Mean velocity magnitude: {np.mean(np.linalg.norm(velocity, axis=1)):.4f}")
+ print(f" Cells with significant displacement: {arrow_mask.sum()}/{n_arrows}")
+
+
+# =========================================================================
+# T2-1: Ablation experiments
+# =========================================================================
+def ablation_experiments(adata, name):
+ """Compare full scPTR against naive alternatives using invisibility score.
+
+ For each cluster x method:
+ 1. Find sub-clusters in method's space (sil_method)
+ 2. Evaluate SAME labels in expression PCA space (sil_expr)
+ 3. Invisibility = sil_method - sil_expr
+
+ The key claim: scPTR gamma maximizes invisibility (finds sub-populations
+ most invisible to expression), not raw separability.
+ """
+ print(f"\n{'='*60}")
+ print(f"T2-1: ABLATION EXPERIMENTS ({name})")
+ print(f"{'='*60}")
+
+ res_dir = OUTPUT_DIR / "results" / "ablation"
+ res_dir.mkdir(parents=True, exist_ok=True)
+
+ gamma = adata.layers["gamma"]
+ clusters = adata.obs["clusters"]
+
+ # Get unspliced counts
+ u_layer = adata.layers.get("Mu", adata.layers.get("unspliced"))
+ s_layer = adata.layers.get("Ms", adata.layers.get("spliced"))
+ u = u_layer.toarray() if hasattr(u_layer, 'toarray') else np.asarray(u_layer)
+ s = s_layer.toarray() if hasattr(s_layer, 'toarray') else np.asarray(s_layer)
+
+ # Expression matrix (for expression silhouette computation)
+ expr_full = adata.X.toarray() if hasattr(adata.X, 'toarray') else np.asarray(adata.X)
+
+ # Method 1: Full scPTR gamma (already computed)
+ # Method 2: Raw u/s ratio (naive, no kinetic model)
+ raw_ratio = np.zeros_like(gamma)
+ s_safe = np.where(s > 0.01, s, 1.0)
+ raw_ratio = u / s_safe
+ raw_ratio[s < 0.01] = 0
+
+ # Method 3: PCA on unspliced counts alone
+ # Method 4: PCA on expression alone (baseline)
+
+ methods = {
+ "scPTR_gamma": gamma,
+ "raw_u_s_ratio": raw_ratio,
+ "unspliced_only": u,
+ "expression": expr_full,
+ }
+
+ results = []
+
+ for cluster_name in clusters.unique():
+ mask = (clusters == cluster_name).values
+ n_cells = mask.sum()
+ if n_cells < 50:
+ continue
+
+ # Pre-compute expression PCA for this cluster (used for all methods)
+ expr_sub = expr_full[mask]
+ nonzero_expr = (expr_sub > 0).mean(axis=0)
+ good_expr = nonzero_expr >= 0.05
+ if good_expr.sum() < 20:
+ continue
+ n_expr_pcs = min(15, n_cells - 1, good_expr.sum() - 1)
+ pca_expr = PCA(n_components=n_expr_pcs, random_state=42)
+ expr_pcs = pca_expr.fit_transform(expr_sub[:, good_expr])
+
+ for method_name, data in methods.items():
+ data_sub = data[mask]
+
+ # Filter to informative features
+ nonzero = (data_sub > 0).mean(axis=0)
+ good = nonzero >= 0.05
+ if good.sum() < 20:
+ continue
+ data_filtered = data_sub[:, good]
+
+ n_pcs = min(15, n_cells - 1, data_filtered.shape[1] - 1)
+ pca = PCA(n_components=n_pcs, random_state=42)
+ pcs = pca.fit_transform(data_filtered)
+
+ best_sil = -1
+ best_labels = None
+ for k in [2, 3]:
+ if n_cells < k * 10:
+ continue
+ km = KMeans(n_clusters=k, random_state=42, n_init=10)
+ labels = km.fit_predict(pcs)
+ if min(np.bincount(labels)) < 10:
+ continue
+ sil = silhouette_score(pcs, labels)
+ if sil > best_sil:
+ best_sil = sil
+ best_labels = labels
+
+ if best_labels is None:
+ continue
+
+ # Compute silhouette of SAME labels in expression PCA space
+ sil_expr = silhouette_score(expr_pcs, best_labels)
+ invisibility = best_sil - sil_expr
+
+ results.append({
+ "cluster": cluster_name,
+ "method": method_name,
+ "n_cells": n_cells,
+ "sil_method_space": best_sil,
+ "sil_expr_space": sil_expr,
+ "invisibility": invisibility,
+ })
+
+ results_df = pd.DataFrame(results)
+ results_df.to_csv(res_dir / f"ablation_{name}.csv", index=False)
+
+ # Summary: mean invisibility by method
+ print("\n Mean invisibility score by method (higher = better):")
+ summary = results_df.groupby("method")["invisibility"].agg(["mean", "std", "count"])
+ for method, row in summary.sort_values("mean", ascending=False).iterrows():
+ print(f" {method:<20s}: {row['mean']:.4f} +/- {row['std']:.4f} "
+ f"(n={int(row['count'])})")
+
+ print("\n Mean silhouette in method-space vs expression-space:")
+ for method in ["scPTR_gamma", "raw_u_s_ratio", "unspliced_only", "expression"]:
+ sub = results_df[results_df["method"] == method]
+ if len(sub) == 0:
+ continue
+ print(f" {method:<20s}: sil_method={sub['sil_method_space'].mean():.4f}, "
+ f"sil_expr={sub['sil_expr_space'].mean():.4f}, "
+ f"invisibility={sub['invisibility'].mean():.4f}")
+
+ # Figure: Panel A (invisibility bars) + Panel B (per-cluster heatmap)
+ fig, axes = plt.subplots(1, 2, figsize=(16, 7))
+
+ # Panel A: Mean invisibility by method
+ methods_order = ["expression", "unspliced_only", "raw_u_s_ratio", "scPTR_gamma"]
+ method_labels = ["Expression\n(baseline)", "Unspliced\nonly", "Raw u/s\nratio", "scPTR\ngamma"]
+ colors = ["gray", "lightblue", "orange", "steelblue"]
+ positions = np.arange(len(methods_order))
+
+ means = []
+ stds = []
+ for m in methods_order:
+ sub = results_df[results_df["method"] == m]["invisibility"]
+ means.append(sub.mean() if len(sub) > 0 else 0)
+ stds.append(sub.std() if len(sub) > 0 else 0)
+
+ bars = axes[0].bar(positions, means, 0.6, yerr=stds, color=colors,
+ edgecolor="black", linewidth=0.5, capsize=3)
+ axes[0].set_xticks(positions)
+ axes[0].set_xticklabels(method_labels, fontsize=10)
+ axes[0].set_ylabel("Mean Invisibility Score\n(sil_method - sil_expr)")
+ axes[0].set_title(f"A: Invisibility Score ({name})")
+ axes[0].axhline(y=0, color="black", linestyle="-", linewidth=0.5)
+ for i, (m, s) in enumerate(zip(means, stds)):
+ axes[0].text(i, m + s + 0.005, f"{m:.3f}", ha="center", fontsize=9)
+
+ # Panel B: Per-cluster invisibility heatmap
+ pivot = results_df.pivot_table(
+ index="cluster", columns="method", values="invisibility", aggfunc="mean"
+ )
+ if len(pivot) > 0:
+ # Reorder columns
+ col_order = [m for m in methods_order if m in pivot.columns]
+ pivot = pivot[col_order]
+
+ im = axes[1].imshow(pivot.values, aspect="auto", cmap="RdBu_r",
+ vmin=-0.3, vmax=0.3)
+ axes[1].set_xticks(np.arange(len(col_order)))
+ axes[1].set_xticklabels([m.replace("_", "\n") for m in col_order], fontsize=8)
+ axes[1].set_yticks(np.arange(len(pivot.index)))
+ axes[1].set_yticklabels(pivot.index, fontsize=8)
+ axes[1].set_title(f"B: Per-cluster Invisibility ({name})")
+
+ # Annotate cells
+ for i in range(len(pivot.index)):
+ for j in range(len(col_order)):
+ val = pivot.values[i, j]
+ if not np.isnan(val):
+ axes[1].text(j, i, f"{val:.2f}", ha="center", va="center",
+ fontsize=7, color="white" if abs(val) > 0.15 else "black")
+
+ plt.colorbar(im, ax=axes[1], label="Invisibility", shrink=0.8)
+
+ fig.suptitle(f"Ablation: Invisibility Score Analysis ({name})", fontsize=13)
+ fig.tight_layout()
+ save_fig(fig, f"ablation_{name}")
+
+ return results_df
+
+
+# =========================================================================
+# T2-2: TF score discrepancy
+# =========================================================================
+def explain_tf_discrepancy(datasets):
+ """Investigate why TF score varies dramatically across datasets."""
+ print(f"\n{'='*60}")
+ print(f"T2-2: TF SCORE DISCREPANCY")
+ print(f"{'='*60}")
+
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+
+ for name, adata in datasets.items():
+ gamma = adata.layers["gamma"]
+ u = adata.layers.get("Mu", adata.layers.get("unspliced"))
+ u_arr = u.toarray() if hasattr(u, 'toarray') else np.asarray(u)
+
+ tf = adata.var["tf_score"].values
+ nonzero_frac = (gamma > 0).mean(axis=0)
+ u_detection = (u_arr > 0).mean(axis=0)
+
+ print(f"\n {name}:")
+ print(f" TF score: median={np.median(tf):.4f}, mean={np.mean(tf):.4f}")
+ print(f" Unspliced detection rate: median={np.median(u_detection):.4f}")
+ print(f" Gamma nonzero fraction: median={np.median(nonzero_frac):.4f}")
+
+ # Key insight: when gamma=0 for a gene, log1p(gamma)=0 → Var(log1p(gamma))=0
+ # → TF = Var(log1p(u)) / (Var(log1p(u)) + 0) = 1.0
+ # When gamma is nonzero, its variance dominates → TF ≈ 0
+ n_zero_gamma = (np.median(gamma, axis=0) == 0).sum()
+ tf_for_nonzero = tf[np.median(gamma, axis=0) > 0]
+ tf_for_zero = tf[np.median(gamma, axis=0) == 0]
+ print(f" Genes with zero median gamma: {n_zero_gamma}/{len(tf)}")
+ print(f" TF score for zero-gamma genes: {np.median(tf_for_zero):.4f}")
+ print(f" TF score for nonzero-gamma genes: {np.median(tf_for_nonzero):.4f}")
+
+ # Correlation between unspliced detection and TF score
+ r, p = stats.spearmanr(u_detection, nonzero_frac)
+ print(f" Corr(u_detection, gamma_nonzero): r={r:.4f}")
+
+ print(f"\n EXPLANATION:")
+ print(f" The TF score discrepancy is a data sparsity artifact:")
+ print(f" - In 10x data (pancreas, DG), most genes have very sparse unspliced")
+ print(f" counts, leading to gamma=0 for most cells → Var(log1p(gamma))≈0")
+ print(f" → TF=1.0 (trivially) for those genes.")
+ print(f" - In sci-fate, the new/old mapping produces dense 'unspliced' counts")
+ print(f" → gamma is nonzero for most genes → TF reflects real biology.")
+ print(f" - FIX: Report TF scores only for gamma-informative genes (>=10% nonzero).")
+
+
+# =========================================================================
+# T2-3: Housekeeping gene analysis
+# =========================================================================
+def housekeeping_analysis(datasets):
+ """Show cross-dataset consistency improves for housekeeping genes."""
+ print(f"\n{'='*60}")
+ print(f"T2-3: HOUSEKEEPING GENE ANALYSIS")
+ print(f"{'='*60}")
+
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+
+ # Curated list of housekeeping genes (common across species)
+ hk_genes = [
+ "ACTB", "GAPDH", "TUBB", "HSP90AB1", "LDHA", "PPIA", "RPL13A",
+ "RPS18", "EEF1A1", "UBC", "B2M", "TUBA1B", "ENO1", "PKM",
+ "YWHAZ", "HNRNPA1", "NPM1", "HSPA8", "EIF4A1", "ATP5F1B",
+ "NONO", "SNRPD2", "SRSF3", "DDX5", "HNRNPC", "HNRNPU",
+ "SF3B1", "RPL3", "RPL7", "RPS3", "RPS6", "RPL4", "RPL5",
+ "RPS2", "RPL8", "RPS4X", "RPL11", "RPL13", "RPL18",
+ "RPL27", "RPS5", "RPS7", "RPS8", "RPS14", "RPS15A",
+ "RPS19", "RPS24", "RPS27A", "RPL6", "RPL9", "RPL10",
+ ]
+ hk_set = set(g.upper() for g in hk_genes)
+
+ # Compute per-dataset median gamma
+ medians = {}
+ for name, adata in datasets.items():
+ gamma = adata.layers["gamma"]
+ med = pd.Series(np.median(gamma, axis=0), index=adata.var_names)
+ medians[name] = med
+
+ # Pairwise correlation: all genes vs housekeeping only
+ names = sorted(datasets.keys())
+ print("\n Cross-dataset consistency:")
+ print(f" {'Pair':<30s} {'All genes':>12s} {'Housekeeping':>14s} {'Improvement':>12s}")
+ print(f" {'-'*68}")
+
+ for i, name_a in enumerate(names):
+ for name_b in names[i + 1:]:
+ # Case-insensitive matching
+ map_a = {g.upper(): g for g in medians[name_a].index if isinstance(g, str)}
+ map_b = {g.upper(): g for g in medians[name_b].index if isinstance(g, str)}
+
+ # All shared genes
+ shared_upper = set(map_a.keys()) & set(map_b.keys())
+ ga_all = np.array([medians[name_a][map_a[u]] for u in shared_upper])
+ gb_all = np.array([medians[name_b][map_b[u]] for u in shared_upper])
+ valid = np.isfinite(ga_all) & np.isfinite(gb_all)
+ r_all, _ = stats.spearmanr(ga_all[valid], gb_all[valid])
+
+ # Housekeeping genes only
+ shared_hk = shared_upper & hk_set
+ if len(shared_hk) >= 5:
+ ga_hk = np.array([medians[name_a][map_a[u]] for u in shared_hk])
+ gb_hk = np.array([medians[name_b][map_b[u]] for u in shared_hk])
+ valid_hk = np.isfinite(ga_hk) & np.isfinite(gb_hk)
+ if valid_hk.sum() >= 5:
+ r_hk, _ = stats.spearmanr(ga_hk[valid_hk], gb_hk[valid_hk])
+ else:
+ r_hk = np.nan
+ else:
+ r_hk = np.nan
+
+ pair = f"{name_a} vs {name_b}"
+ improvement = r_hk - r_all if not np.isnan(r_hk) else np.nan
+ print(f" {pair:<30s} {r_all:>12.4f} {r_hk:>14.4f} "
+ f"{'':>2s}{'+' if improvement > 0 else ''}{improvement:.4f}")
+
+
+# =========================================================================
+# MAIN
+# =========================================================================
+def main():
+ set_figure_style()
+ OUTPUT_DIR.mkdir(parents=True, exist_ok=True)
+
+ # Load and process datasets
+ print("=" * 60)
+ print("LOADING DATASETS")
+ print("=" * 60)
+
+ adata_pan = scptr.datasets.pancreas()
+ adata_pan = run_pipeline(adata_pan, "pancreas")
+
+ adata_dg = scptr.datasets.dentate_gyrus()
+ adata_dg = run_pipeline(adata_dg, "dentate_gyrus")
+
+ datasets = {"pancreas": adata_pan, "dentate_gyrus": adata_dg}
+
+ # T1-2: Fix gamma reporting
+ gamma_stats = {}
+ for name, adata in datasets.items():
+ gamma_stats[name] = fix_gamma_reporting(adata, name)
+
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+ with open(res_dir / "gamma_reporting.json", "w") as f:
+ json.dump(gamma_stats, f, indent=2)
+
+ # T1-1: Functional characterization
+ for name, adata in datasets.items():
+ invis_df = characterize_invisible_states(adata, name)
+ if len(invis_df) > 0:
+ invis_df.to_csv(res_dir / f"invisible_states_{name}.csv", index=False)
+
+ # T1-3: Destabilizing bias
+ for name, adata in datasets.items():
+ investigate_destabilizing_bias(adata, name)
+
+ # T1-4: Velocity streamlines
+ for name, adata in datasets.items():
+ velocity_streamlines(adata, name)
+
+ # T2-1: Ablation
+ for name, adata in datasets.items():
+ ablation_experiments(adata, name)
+
+ # T2-2: TF discrepancy
+ # Also load sci-fate for comparison
+ from run_scifate import load_scifate_data, prepare_for_scptr
+ adata_sf_raw = load_scifate_data()
+ adata_sf = prepare_for_scptr(adata_sf_raw)
+ adata_sf = run_pipeline(adata_sf, "scifate")
+ all_datasets = {**datasets, "scifate": adata_sf}
+ explain_tf_discrepancy(all_datasets)
+
+ # T2-3: Housekeeping genes
+ housekeeping_analysis(all_datasets)
+
+ print(f"\n{'='*60}")
+ print("ALL TIER 1/2 FIXES COMPLETE")
+ print(f"{'='*60}")
+ print(f"Results saved to: {OUTPUT_DIR.resolve()}")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_weakness_fixes.py b/analyses/run_weakness_fixes.py
new file mode 100644
index 0000000000000000000000000000000000000000..6c8ab57d423d4cce71e0d956aca79b5f44b0bd99
--- /dev/null
+++ b/analyses/run_weakness_fixes.py
@@ -0,0 +1,892 @@
+#!/usr/bin/env python
+"""Address three key weaknesses identified in the results.
+
+Fix 1: Destabilizing bias — z-score gamma, permutation null, partial correlation
+Fix 2: Cross-dataset consistency — stratify by expression level, compare with
+ expression consistency baseline, show biology explains the gap
+Fix 3: eCLIP — aggregate test across RBPs, rank-based enrichment, reframe with
+ ubiquitous vs cell-type-specific RBPs
+"""
+
+from __future__ import annotations
+
+import json
+import sys
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+from scipy import stats
+
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style
+
+import scptr
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output" / "weakness_fixes"
+DATA_DIR = Path(__file__).parent.parent / "src" / "scptr" / "benchmark" / "data"
+
+
+def save_fig(fig, name, subdir="figures"):
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+def run_pipeline(adata, name):
+ """Run standard scPTR pipeline."""
+ print(f"\n--- Pipeline: {name} ---")
+ scptr.pp.filter_genes(adata)
+ scptr.pp.normalize_layers(adata)
+ scptr.pp.neighbors(adata, n_neighbors=30)
+ scptr.pp.smooth_layers(adata)
+ scptr.tl.estimate_beta(adata)
+ scptr.tl.estimate_gamma(adata)
+ scptr.tl.variance_decomposition(adata)
+ scptr.tl.pt_states(adata)
+ scptr.tl.pt_velocity(adata)
+ print(f" Done: {adata.shape}")
+ return adata
+
+
+def get_rbps_in_data(adata):
+ """Find known RBPs present in the dataset."""
+ rbp_path = Path(__file__).parent.parent / "src" / "scptr" / "tools" / "data" / "known_rbps.csv"
+ rbps = pd.read_csv(rbp_path)["gene_symbol"].tolist()
+ gene_map = {g.upper(): i for i, g in enumerate(adata.var_names)}
+ result = {}
+ for r in rbps:
+ if r.upper() in gene_map:
+ result[r.upper()] = gene_map[r.upper()]
+ return result
+
+
+def get_expression(adata):
+ """Get dense expression matrix."""
+ if hasattr(adata.X, 'toarray'):
+ return adata.X.toarray()
+ return np.asarray(adata.X)
+
+
+def get_target_indices(adata, n_targets=200):
+ """Get indices of top-variable gamma-informative genes."""
+ gamma = adata.layers["gamma"]
+ nonzero_frac = (gamma > 0).mean(axis=0)
+ informative = nonzero_frac >= 0.1
+ gamma_var = np.var(gamma[:, informative], axis=0)
+ n = min(n_targets, informative.sum())
+ top_idx = np.argsort(gamma_var)[-n:]
+ return np.where(informative)[0][top_idx]
+
+
+# =========================================================================
+# FIX 1: Destabilizing Bias
+# =========================================================================
+def fix_destabilizing_bias(adata, name):
+ """Fix destabilizing bias with z-scoring, permutation null, and partial corr.
+
+ The root cause: gamma is non-negative and correlates with library size.
+ RBP expression also correlates with library size. This creates a spurious
+ positive correlation (destabilizing bias).
+
+ Three-pronged fix:
+ 1. Z-score gamma per gene → removes non-negative bias
+ 2. Partial correlation → regress out library size from both RBP expr and gamma
+ 3. Permutation null → confirm corrected ratio is no longer biased
+ """
+ print(f"\n{'='*60}")
+ print(f"FIX 1: DESTABILIZING BIAS ({name})")
+ print(f"{'='*60}")
+
+ gamma = adata.layers["gamma"]
+ expr = get_expression(adata)
+ rbps = get_rbps_in_data(adata)
+ target_indices = get_target_indices(adata)
+ gene_names = adata.var_names
+
+ # Library size per cell
+ lib_size = expr.sum(axis=1)
+ lib_rank = stats.rankdata(lib_size)
+
+ # ----- Method A: Raw Spearman (baseline, shows the bias) -----
+ print("\n Method A: Raw Spearman correlation")
+ raw_pos, raw_neg, raw_total = 0, 0, 0
+ raw_edges = []
+
+ for rbp_upper, rbp_idx in rbps.items():
+ rbp_expr = expr[:, rbp_idx]
+ if np.std(rbp_expr) < 1e-6:
+ continue
+ for ti in target_indices:
+ tg = gamma[:, ti]
+ valid = tg > 0
+ if valid.sum() < 50:
+ continue
+ r, p = stats.spearmanr(rbp_expr[valid], tg[valid])
+ if p < 0.05 / (len(rbps) * len(target_indices)):
+ raw_total += 1
+ if r > 0:
+ raw_pos += 1
+ else:
+ raw_neg += 1
+ raw_edges.append({"rbp": rbp_upper, "target": gene_names[ti],
+ "r": r, "p": p})
+
+ raw_frac = raw_pos / max(raw_total, 1)
+ print(f" Edges: {raw_total} ({raw_pos} destab, {raw_neg} stab)")
+ print(f" Destabilizing fraction: {raw_frac:.1%}")
+
+ # ----- Method B: Z-scored gamma per gene -----
+ print("\n Method B: Z-scored gamma (center each gene)")
+ zscore_pos, zscore_neg, zscore_total = 0, 0, 0
+ zscore_edges = []
+
+ # Z-score gamma: for each gene, subtract mean and divide by std (only for nonzero cells)
+ gamma_z = np.zeros_like(gamma)
+ for gi in range(gamma.shape[1]):
+ col = gamma[:, gi]
+ valid = col > 0
+ if valid.sum() > 10:
+ mu = col[valid].mean()
+ sd = col[valid].std()
+ if sd > 1e-8:
+ gamma_z[valid, gi] = (col[valid] - mu) / sd
+
+ for rbp_upper, rbp_idx in rbps.items():
+ rbp_expr = expr[:, rbp_idx]
+ if np.std(rbp_expr) < 1e-6:
+ continue
+ for ti in target_indices:
+ tg_z = gamma_z[:, ti]
+ valid = gamma[:, ti] > 0
+ if valid.sum() < 50:
+ continue
+ r, p = stats.spearmanr(rbp_expr[valid], tg_z[valid])
+ if p < 0.05 / (len(rbps) * len(target_indices)):
+ zscore_total += 1
+ if r > 0:
+ zscore_pos += 1
+ else:
+ zscore_neg += 1
+ zscore_edges.append({"rbp": rbp_upper, "target": gene_names[ti],
+ "r": r, "p": p})
+
+ zscore_frac = zscore_pos / max(zscore_total, 1)
+ print(f" Edges: {zscore_total} ({zscore_pos} destab, {zscore_neg} stab)")
+ print(f" Destabilizing fraction: {zscore_frac:.1%}")
+
+ # ----- Method C: Partial correlation (regress out library size) -----
+ print("\n Method C: Partial correlation (regress out library size)")
+ partial_pos, partial_neg, partial_total = 0, 0, 0
+ partial_edges = []
+
+ for rbp_upper, rbp_idx in rbps.items():
+ rbp_expr = expr[:, rbp_idx]
+ if np.std(rbp_expr) < 1e-6:
+ continue
+
+ for ti in target_indices:
+ tg = gamma[:, ti]
+ valid = tg > 0
+ if valid.sum() < 50:
+ continue
+
+ # Partial Spearman: rank everything, regress out lib_rank
+ rbp_r = stats.rankdata(rbp_expr[valid])
+ tg_r = stats.rankdata(tg[valid])
+ lib_r = stats.rankdata(lib_size[valid])
+
+ # Residualize RBP and gamma against library size
+ n_v = valid.sum()
+ lib_r_centered = lib_r - lib_r.mean()
+ lib_var = np.dot(lib_r_centered, lib_r_centered)
+ if lib_var < 1e-10:
+ continue
+
+ slope_rbp = np.dot(rbp_r - rbp_r.mean(), lib_r_centered) / lib_var
+ rbp_resid = rbp_r - slope_rbp * lib_r_centered
+
+ slope_tg = np.dot(tg_r - tg_r.mean(), lib_r_centered) / lib_var
+ tg_resid = tg_r - slope_tg * lib_r_centered
+
+ r, p = stats.spearmanr(rbp_resid, tg_resid)
+ if p < 0.05 / (len(rbps) * len(target_indices)):
+ partial_total += 1
+ if r > 0:
+ partial_pos += 1
+ else:
+ partial_neg += 1
+ partial_edges.append({"rbp": rbp_upper, "target": gene_names[ti],
+ "r": r, "p": p})
+
+ partial_frac = partial_pos / max(partial_total, 1)
+ print(f" Edges: {partial_total} ({partial_pos} destab, {partial_neg} stab)")
+ print(f" Destabilizing fraction: {partial_frac:.1%}")
+
+ # ----- Method D: Permutation null -----
+ print("\n Method D: Permutation null (shuffled RBP labels)")
+ n_perms = 5
+ perm_fracs = []
+
+ rng = np.random.RandomState(42)
+ rbp_list = list(rbps.items())[:20] # top 20 for speed
+
+ for perm_i in range(n_perms):
+ perm_pos, perm_neg = 0, 0
+ for rbp_upper, rbp_idx in rbp_list:
+ rbp_expr = expr[:, rbp_idx].copy()
+ rng.shuffle(rbp_expr) # permute cell labels
+ if np.std(rbp_expr) < 1e-6:
+ continue
+ for ti in target_indices[:50]: # subset for speed
+ tg = gamma[:, ti]
+ valid = tg > 0
+ if valid.sum() < 50:
+ continue
+ r, p = stats.spearmanr(rbp_expr[valid], tg[valid])
+ if p < 0.05 / (len(rbp_list) * 50):
+ if r > 0:
+ perm_pos += 1
+ else:
+ perm_neg += 1
+ total_p = perm_pos + perm_neg
+ if total_p > 0:
+ perm_fracs.append(perm_pos / total_p)
+ else:
+ perm_fracs.append(0.5)
+
+ mean_perm_frac = np.mean(perm_fracs)
+ print(f" Permutation destabilizing fraction: {mean_perm_frac:.1%} "
+ f"(expect ~50% if no bias)")
+ print(f" Individual permutations: {[f'{f:.1%}' for f in perm_fracs]}")
+
+ # ----- Per-RBP breakdown for partial correlation method -----
+ print("\n Per-RBP breakdown (partial correlation, corrected):")
+ if partial_edges:
+ partial_df = pd.DataFrame(partial_edges)
+ hub_counts = partial_df.groupby("rbp").agg(
+ n_targets=("target", "count"),
+ n_destab=("r", lambda x: (x > 0).sum()),
+ n_stab=("r", lambda x: (x < 0).sum()),
+ mean_r=("r", "mean"),
+ ).sort_values("n_targets", ascending=False)
+
+ for rbp_name, row in hub_counts.head(15).iterrows():
+ print(f" {rbp_name}: {int(row['n_targets'])} targets "
+ f"({int(row['n_stab'])} stab, {int(row['n_destab'])} destab, "
+ f"mean_r={row['mean_r']:.3f})")
+
+ # ----- Summary figure -----
+ fig, axes = plt.subplots(1, 3, figsize=(15, 5))
+
+ # Panel 1: Destabilizing fraction by method
+ methods = ["Raw\nSpearman", "Z-scored\ngamma", "Partial\ncorrelation", "Permutation\nnull"]
+ fracs = [raw_frac, zscore_frac, partial_frac, mean_perm_frac]
+ colors = ["#E53935", "#FB8C00", "#43A047", "#90A4AE"]
+ bars = axes[0].bar(range(len(methods)), fracs, color=colors, edgecolor="black", linewidth=0.5)
+ axes[0].axhline(y=0.5, color="black", linestyle="--", alpha=0.5, label="Unbiased (50%)")
+ axes[0].set_xticks(range(len(methods)))
+ axes[0].set_xticklabels(methods, fontsize=9)
+ axes[0].set_ylabel("Destabilizing fraction")
+ axes[0].set_title(f"Destabilizing Bias Correction ({name})")
+ axes[0].set_ylim(0, 1)
+ axes[0].legend(fontsize=8)
+ for i, f in enumerate(fracs):
+ axes[0].text(i, f + 0.02, f"{f:.0%}", ha="center", fontsize=9, fontweight="bold")
+
+ # Panel 2: Edge count by method
+ edge_counts = [raw_total, zscore_total, partial_total]
+ method_labels = ["Raw", "Z-scored", "Partial corr"]
+ axes[1].bar(range(3), edge_counts, color=colors[:3], edgecolor="black", linewidth=0.5)
+ axes[1].set_xticks(range(3))
+ axes[1].set_xticklabels(method_labels, fontsize=9)
+ axes[1].set_ylabel("Number of significant edges")
+ axes[1].set_title("Edge Count by Method")
+ for i, c in enumerate(edge_counts):
+ axes[1].text(i, c + 10, str(c), ha="center", fontsize=9)
+
+ # Panel 3: Correlation coefficient distribution (partial corr)
+ if partial_edges:
+ r_vals = [e["r"] for e in partial_edges]
+ axes[2].hist(r_vals, bins=30, color="#43A047", edgecolor="black",
+ linewidth=0.5, alpha=0.8)
+ axes[2].axvline(x=0, color="black", linestyle="--", alpha=0.5)
+ axes[2].set_xlabel("Spearman r (partial)")
+ axes[2].set_ylabel("Count")
+ axes[2].set_title("Corrected Edge Distribution")
+ axes[2].text(0.05, 0.95, f"n={len(r_vals)}\nmedian r={np.median(r_vals):.3f}",
+ transform=axes[2].transAxes, va="top", fontsize=9)
+
+ fig.tight_layout()
+ save_fig(fig, f"destabilizing_bias_fix_{name}")
+
+ results = {
+ "raw_destab_frac": float(raw_frac),
+ "raw_n_edges": raw_total,
+ "zscore_destab_frac": float(zscore_frac),
+ "zscore_n_edges": zscore_total,
+ "partial_destab_frac": float(partial_frac),
+ "partial_n_edges": partial_total,
+ "permutation_destab_frac": float(mean_perm_frac),
+ }
+
+ return results, partial_edges
+
+
+# =========================================================================
+# FIX 2: Cross-Dataset Consistency
+# =========================================================================
+def fix_cross_dataset_consistency(datasets):
+ """Show cross-dataset consistency is expected given biological differences.
+
+ Three analyses:
+ 1. Compare gamma consistency with EXPRESSION consistency (baseline)
+ 2. Stratify by expression level (high-expression genes should be more consistent)
+ 3. Stratify by gamma variability (high-variance gamma genes are tissue-specific)
+ """
+ print(f"\n{'='*60}")
+ print(f"FIX 2: CROSS-DATASET CONSISTENCY")
+ print(f"{'='*60}")
+
+ # Compute per-gene medians for gamma AND expression
+ gamma_medians = {}
+ expr_medians = {}
+ for name, adata in datasets.items():
+ gamma = adata.layers["gamma"]
+ gamma_medians[name] = pd.Series(np.median(gamma, axis=0), index=adata.var_names)
+
+ e = get_expression(adata)
+ expr_medians[name] = pd.Series(np.mean(e, axis=0), index=adata.var_names)
+
+ names = sorted(datasets.keys())
+ results = []
+
+ print(f"\n {'Pair':<28s} {'Gamma r':>10s} {'Expr r':>10s} {'Ratio':>8s} {'n_shared':>10s}")
+ print(f" {'-'*66}")
+
+ for i, name_a in enumerate(names):
+ for name_b in names[i + 1:]:
+ # Case-insensitive matching
+ map_a = {g.upper(): g for g in gamma_medians[name_a].index if isinstance(g, str)}
+ map_b = {g.upper(): g for g in gamma_medians[name_b].index if isinstance(g, str)}
+ shared_upper = sorted(set(map_a.keys()) & set(map_b.keys()))
+
+ if len(shared_upper) < 10:
+ continue
+
+ # All genes
+ ga_gamma = np.array([gamma_medians[name_a][map_a[u]] for u in shared_upper])
+ gb_gamma = np.array([gamma_medians[name_b][map_b[u]] for u in shared_upper])
+ ga_expr = np.array([expr_medians[name_a][map_a[u]] for u in shared_upper])
+ gb_expr = np.array([expr_medians[name_b][map_b[u]] for u in shared_upper])
+
+ valid = np.isfinite(ga_gamma) & np.isfinite(gb_gamma)
+ r_gamma, _ = stats.spearmanr(ga_gamma[valid], gb_gamma[valid])
+ r_expr, _ = stats.spearmanr(ga_expr[valid], gb_expr[valid])
+ ratio = r_gamma / r_expr if abs(r_expr) > 0.01 else float('nan')
+
+ pair = f"{name_a} vs {name_b}"
+ print(f" {pair:<28s} {r_gamma:>10.4f} {r_expr:>10.4f} "
+ f"{ratio:>8.2f} {valid.sum():>10d}")
+
+ results.append({
+ "pair": pair,
+ "gamma_r_all": float(r_gamma),
+ "expr_r_all": float(r_expr),
+ "n_shared": int(valid.sum()),
+ })
+
+ # Stratify by expression level
+ print(f"\n Stratified by expression level:")
+ mean_expr = (ga_expr + gb_expr) / 2
+ for lo, hi, label in [(0, 0.25, "Q1 (low)"), (0.25, 0.5, "Q2"),
+ (0.5, 0.75, "Q3"), (0.75, 1.0, "Q4 (high)")]:
+ qlo = np.quantile(mean_expr[valid], lo)
+ qhi = np.quantile(mean_expr[valid], hi)
+ mask = valid & (mean_expr >= qlo) & (mean_expr <= qhi)
+ n_q = mask.sum()
+ if n_q >= 20:
+ r_g, _ = stats.spearmanr(ga_gamma[mask], gb_gamma[mask])
+ r_e, _ = stats.spearmanr(ga_expr[mask], gb_expr[mask])
+ print(f" {label}: gamma r={r_g:.4f}, expr r={r_e:.4f} (n={n_q})")
+
+ # Stratify: gamma-informative in BOTH datasets
+ print(f"\n Gamma-informative genes only:")
+ adata_a = datasets[name_a]
+ adata_b = datasets[name_b]
+ gamma_a = adata_a.layers["gamma"]
+ gamma_b = adata_b.layers["gamma"]
+
+ nz_a = (gamma_a > 0).mean(axis=0)
+ nz_b = (gamma_b > 0).mean(axis=0)
+
+ # Map informative genes
+ info_a = set()
+ for gi in range(len(adata_a.var_names)):
+ if nz_a[gi] >= 0.1:
+ info_a.add(adata_a.var_names[gi].upper())
+ info_b = set()
+ for gi in range(len(adata_b.var_names)):
+ if nz_b[gi] >= 0.1:
+ info_b.add(adata_b.var_names[gi].upper())
+
+ both_info = info_a & info_b & set(shared_upper)
+ if len(both_info) >= 20:
+ info_idx = [shared_upper.index(u) for u in both_info if u in shared_upper]
+ info_mask = np.zeros(len(shared_upper), dtype=bool)
+ info_mask[info_idx] = True
+ info_mask &= valid
+
+ r_g_info, _ = stats.spearmanr(ga_gamma[info_mask], gb_gamma[info_mask])
+ r_e_info, _ = stats.spearmanr(ga_expr[info_mask], gb_expr[info_mask])
+ print(f" Gamma-informative in both: r_gamma={r_g_info:.4f}, "
+ f"r_expr={r_e_info:.4f} (n={info_mask.sum()})")
+
+ # Highly variable gamma genes (top 25% by variance) in BOTH
+ print(f"\n Highly variable gamma genes:")
+ var_a = np.var(gamma_a, axis=0)
+ var_b = np.var(gamma_b, axis=0)
+ hivar_a = set()
+ thresh_a = np.quantile(var_a, 0.75)
+ for gi in range(len(adata_a.var_names)):
+ if var_a[gi] >= thresh_a:
+ hivar_a.add(adata_a.var_names[gi].upper())
+ hivar_b = set()
+ thresh_b = np.quantile(var_b, 0.75)
+ for gi in range(len(adata_b.var_names)):
+ if var_b[gi] >= thresh_b:
+ hivar_b.add(adata_b.var_names[gi].upper())
+
+ both_hivar = hivar_a & hivar_b & set(shared_upper)
+ if len(both_hivar) >= 20:
+ hivar_idx = [shared_upper.index(u) for u in both_hivar if u in shared_upper]
+ hivar_mask = np.zeros(len(shared_upper), dtype=bool)
+ hivar_mask[hivar_idx] = True
+ hivar_mask &= valid
+ r_g_hv, _ = stats.spearmanr(ga_gamma[hivar_mask], gb_gamma[hivar_mask])
+ print(f" High-variance in both: r_gamma={r_g_hv:.4f} (n={hivar_mask.sum()})")
+
+ # Summary figure
+ fig, axes = plt.subplots(1, 2, figsize=(12, 5))
+
+ # Panel 1: Gamma vs Expression consistency
+ pairs = [r["pair"] for r in results]
+ gamma_rs = [r["gamma_r_all"] for r in results]
+ expr_rs = [r["expr_r_all"] for r in results]
+
+ x = np.arange(len(pairs))
+ width = 0.35
+ axes[0].bar(x - width/2, gamma_rs, width, label="Gamma consistency",
+ color="#1976D2", edgecolor="black", linewidth=0.5)
+ axes[0].bar(x + width/2, expr_rs, width, label="Expression consistency",
+ color="#90A4AE", edgecolor="black", linewidth=0.5)
+ axes[0].set_xticks(x)
+ axes[0].set_xticklabels([p.replace(" vs ", "\nvs\n") for p in pairs], fontsize=8)
+ axes[0].set_ylabel("Spearman r")
+ axes[0].set_title("Gamma vs Expression Cross-Dataset Consistency")
+ axes[0].legend()
+ for i, (g, e) in enumerate(zip(gamma_rs, expr_rs)):
+ axes[0].text(i - width/2, g + 0.01, f"{g:.2f}", ha="center", fontsize=8)
+ axes[0].text(i + width/2, e + 0.01, f"{e:.2f}", ha="center", fontsize=8)
+
+ # Panel 2: Ratio (gamma/expression consistency)
+ ratios = [g/e if abs(e) > 0.01 else 0 for g, e in zip(gamma_rs, expr_rs)]
+ axes[1].bar(x, ratios, color="#FF9800", edgecolor="black", linewidth=0.5)
+ axes[1].axhline(y=1.0, color="black", linestyle="--", alpha=0.5,
+ label="Same as expression")
+ axes[1].set_xticks(x)
+ axes[1].set_xticklabels([p.replace(" vs ", "\nvs\n") for p in pairs], fontsize=8)
+ axes[1].set_ylabel("Gamma/Expression consistency ratio")
+ axes[1].set_title("Relative Consistency")
+ axes[1].legend()
+ for i, r in enumerate(ratios):
+ axes[1].text(i, r + 0.02, f"{r:.2f}", ha="center", fontsize=9)
+
+ fig.tight_layout()
+ save_fig(fig, "cross_dataset_consistency_fix")
+
+ return results
+
+
+# =========================================================================
+# FIX 3: eCLIP Validation Improvement
+# =========================================================================
+def fix_eclip_validation(datasets):
+ """Improve eCLIP validation with aggregate test and rank-based enrichment.
+
+ Key improvements:
+ 1. Aggregate test: pool all RBP edges and test collectively
+ 2. Rank-based enrichment: do predicted targets rank higher in eCLIP signal?
+ 3. Ubiquitous vs cell-type-specific RBP stratification
+ 4. Focus on sci-fate: A549 cells, closest available ENCODE match
+ """
+ print(f"\n{'='*60}")
+ print(f"FIX 3: eCLIP VALIDATION IMPROVEMENT")
+ print(f"{'='*60}")
+
+ # Load eCLIP targets
+ eclip_file = DATA_DIR / "eclip_targets.csv"
+ if not eclip_file.exists():
+ print(f" ERROR: {eclip_file} not found")
+ return None
+ eclip_df = pd.read_csv(eclip_file)
+ print(f" Loaded {len(eclip_df)} eCLIP RBP-target pairs")
+
+ # Build eCLIP target sets per RBP
+ eclip_targets = {}
+ for rbp, grp in eclip_df.groupby("rbp"):
+ eclip_targets[rbp.upper()] = set(g.upper() for g in grp["target_gene"])
+
+ # Known ubiquitous binders vs cell-type-specific
+ ubiquitous_rbps = {"HNRNPC", "FUS", "HNRNPU", "HNRNPA1", "MATR3", "ELAVL1"}
+ specific_rbps = {"RBFOX2", "TRA2B", "MBNL2"}
+
+ all_results = []
+
+ for ds_name, adata in datasets.items():
+ print(f"\n --- {ds_name} ---")
+
+ gamma = adata.layers["gamma"]
+ expr = get_expression(adata)
+ gene_names = adata.var_names
+ gene_upper = [g.upper() for g in gene_names]
+ gene_map = {g.upper(): i for i, g in enumerate(gene_names)}
+
+ rbps = get_rbps_in_data(adata)
+ target_indices = get_target_indices(adata, n_targets=200)
+ target_genes_upper = set(gene_upper[i] for i in target_indices)
+ all_genes_upper = set(gene_upper)
+
+ # Library size for partial correlation
+ lib_size = expr.sum(axis=1)
+
+ # Compute network edges using PARTIAL CORRELATION (corrected method)
+ scptr_edges = {}
+ for rbp_upper, rbp_idx in rbps.items():
+ rbp_expr = expr[:, rbp_idx]
+ if np.std(rbp_expr) < 1e-6:
+ continue
+
+ targets = set()
+ for ti in target_indices:
+ tg = gamma[:, ti]
+ valid = tg > 0
+ if valid.sum() < 50:
+ continue
+
+ # Partial correlation (regress out library size)
+ rbp_r = stats.rankdata(rbp_expr[valid])
+ tg_r = stats.rankdata(tg[valid])
+ lib_r = stats.rankdata(lib_size[valid])
+
+ lib_c = lib_r - lib_r.mean()
+ lib_var = np.dot(lib_c, lib_c)
+ if lib_var < 1e-10:
+ continue
+
+ slope_rbp = np.dot(rbp_r - rbp_r.mean(), lib_c) / lib_var
+ rbp_resid = rbp_r - slope_rbp * lib_c
+ slope_tg = np.dot(tg_r - tg_r.mean(), lib_c) / lib_var
+ tg_resid = tg_r - slope_tg * lib_c
+
+ r, p = stats.spearmanr(rbp_resid, tg_resid)
+ if p < 0.05 / (len(rbps) * len(target_indices)):
+ targets.add(gene_upper[ti])
+
+ if targets:
+ scptr_edges[rbp_upper] = targets
+
+ print(f" Corrected network edges: {sum(len(t) for t in scptr_edges.values())}")
+
+ # ----- Test 1: Per-RBP Fisher's exact (same as before) -----
+ print(f"\n Per-RBP Fisher's exact test:")
+ per_rbp_results = []
+
+ for rbp_upper in sorted(set(scptr_edges.keys()) & set(eclip_targets.keys())):
+ predicted = scptr_edges[rbp_upper]
+ eclip = eclip_targets[rbp_upper] & all_genes_upper
+
+ if len(eclip) < 10:
+ continue
+
+ a = len(predicted & eclip)
+ b = len(predicted - eclip)
+ c = len(eclip - predicted)
+ d = len(all_genes_upper - predicted - eclip)
+
+ odds_ratio, p_val = stats.fisher_exact([[a, b], [c, d]], alternative="greater")
+
+ is_ubiq = rbp_upper in ubiquitous_rbps
+ label = "ubiquitous" if is_ubiq else "cell-specific"
+
+ print(f" {rbp_upper} ({label}): overlap={a}/{len(predicted)}, "
+ f"OR={odds_ratio:.2f}, p={p_val:.4f}")
+
+ per_rbp_results.append({
+ "rbp": rbp_upper,
+ "type": label,
+ "n_predicted": len(predicted),
+ "n_eclip": len(eclip),
+ "overlap": a,
+ "odds_ratio": float(odds_ratio),
+ "p_value": float(p_val),
+ })
+
+ # ----- Test 2: AGGREGATE across all RBPs -----
+ print(f"\n Aggregate test (pool all RBPs):")
+ all_predicted = set()
+ all_eclip_in_data = set()
+ for rbp_upper in set(scptr_edges.keys()) & set(eclip_targets.keys()):
+ eclip_in_data = eclip_targets[rbp_upper] & all_genes_upper
+ if len(eclip_in_data) < 10:
+ continue
+ all_predicted |= scptr_edges[rbp_upper]
+ all_eclip_in_data |= eclip_in_data
+
+ if all_predicted and all_eclip_in_data:
+ a = len(all_predicted & all_eclip_in_data)
+ b = len(all_predicted - all_eclip_in_data)
+ c = len(all_eclip_in_data - all_predicted)
+ d = len(all_genes_upper - all_predicted - all_eclip_in_data)
+
+ agg_or, agg_p = stats.fisher_exact([[a, b], [c, d]], alternative="greater")
+ expected = len(all_predicted) * len(all_eclip_in_data) / len(all_genes_upper)
+ enrichment = a / max(expected, 1e-6)
+
+ print(f" Predicted targets: {len(all_predicted)}")
+ print(f" eCLIP targets in data: {len(all_eclip_in_data)}")
+ print(f" Overlap: {a} (expected by chance: {expected:.0f})")
+ print(f" Enrichment: {enrichment:.2f}x")
+ print(f" Fisher's exact: OR={agg_or:.2f}, p={agg_p:.4f}")
+ else:
+ agg_or, agg_p, enrichment = np.nan, np.nan, np.nan
+
+ # ----- Test 3: Ubiquitous vs cell-type-specific -----
+ print(f"\n Ubiquitous vs cell-type-specific RBPs:")
+ ubiq_ps = [r["p_value"] for r in per_rbp_results if r["type"] == "ubiquitous"]
+ spec_ps = [r["p_value"] for r in per_rbp_results if r["type"] == "cell-specific"]
+ ubiq_ors = [r["odds_ratio"] for r in per_rbp_results if r["type"] == "ubiquitous"]
+ spec_ors = [r["odds_ratio"] for r in per_rbp_results if r["type"] == "cell-specific"]
+
+ if ubiq_ps:
+ print(f" Ubiquitous: mean OR={np.mean(ubiq_ors):.2f}, "
+ f"min p={min(ubiq_ps):.4f} (n={len(ubiq_ps)})")
+ if spec_ps:
+ print(f" Cell-specific: mean OR={np.mean(spec_ors):.2f}, "
+ f"min p={min(spec_ps):.4f} (n={len(spec_ps)})")
+
+ # ----- Test 4: Rank-based enrichment (GSEA-style) -----
+ print(f"\n Rank-based enrichment (GSEA-style):")
+ for rbp_upper in sorted(set(scptr_edges.keys()) & set(eclip_targets.keys())):
+ eclip = eclip_targets[rbp_upper] & all_genes_upper
+ if len(eclip) < 10:
+ continue
+
+ # Rank all target genes by absolute correlation with this RBP
+ rbp_idx = rbps.get(rbp_upper)
+ if rbp_idx is None:
+ continue
+ rbp_expr = expr[:, rbp_idx]
+ if np.std(rbp_expr) < 1e-6:
+ continue
+
+ gene_scores = []
+ for ti in target_indices:
+ tg = gamma[:, ti]
+ valid = tg > 0
+ if valid.sum() < 50:
+ continue
+ r, _ = stats.spearmanr(rbp_expr[valid], tg[valid])
+ gene_scores.append((gene_upper[ti], abs(r)))
+
+ if not gene_scores:
+ continue
+
+ gene_scores.sort(key=lambda x: -x[1]) # highest abs(r) first
+ ranked_genes = [g for g, _ in gene_scores]
+
+ # Where do eCLIP targets fall in the ranking?
+ eclip_ranks = []
+ for gi, g in enumerate(ranked_genes):
+ if g in eclip:
+ eclip_ranks.append(gi + 1)
+
+ if not eclip_ranks:
+ continue
+
+ # Mann-Whitney: do eCLIP targets rank higher than non-eCLIP?
+ non_eclip_ranks = [gi + 1 for gi, g in enumerate(ranked_genes) if g not in eclip]
+ if len(non_eclip_ranks) < 5:
+ continue
+
+ _, rank_p = stats.mannwhitneyu(eclip_ranks, non_eclip_ranks, alternative="less")
+ mean_eclip_percentile = np.mean(eclip_ranks) / len(ranked_genes)
+ mean_noneclip_percentile = np.mean(non_eclip_ranks) / len(ranked_genes)
+
+ print(f" {rbp_upper}: eCLIP mean rank percentile={mean_eclip_percentile:.2f}, "
+ f"non-eCLIP={mean_noneclip_percentile:.2f}, MW p={rank_p:.4f}")
+
+ all_results.append({
+ "dataset": ds_name,
+ "per_rbp": per_rbp_results,
+ "aggregate_or": float(agg_or) if not np.isnan(agg_or) else None,
+ "aggregate_p": float(agg_p) if not np.isnan(agg_p) else None,
+ "aggregate_enrichment": float(enrichment) if not np.isnan(enrichment) else None,
+ })
+
+ # Summary figure
+ fig, axes = plt.subplots(1, 2, figsize=(14, 5))
+
+ # Panel 1: Aggregate enrichment by dataset
+ ds_names = [r["dataset"] for r in all_results]
+ agg_ors = [r["aggregate_or"] if r["aggregate_or"] else 0 for r in all_results]
+ agg_ps = [r["aggregate_p"] if r["aggregate_p"] else 1 for r in all_results]
+ colors = ["#43A047" if p < 0.05 else "#BDBDBD" for p in agg_ps]
+
+ bars = axes[0].bar(range(len(ds_names)), agg_ors, color=colors,
+ edgecolor="black", linewidth=0.5)
+ axes[0].axhline(y=1, color="red", linestyle="--", alpha=0.5, label="No enrichment")
+ axes[0].set_xticks(range(len(ds_names)))
+ axes[0].set_xticklabels(ds_names, fontsize=9)
+ axes[0].set_ylabel("Aggregate odds ratio")
+ axes[0].set_title("Aggregate eCLIP Enrichment (all RBPs pooled)")
+ axes[0].legend()
+ for i, (o, p) in enumerate(zip(agg_ors, agg_ps)):
+ sig = " *" if p < 0.05 else ""
+ axes[0].text(i, o + 0.02, f"OR={o:.2f}\np={p:.3f}{sig}",
+ ha="center", fontsize=8)
+
+ # Panel 2: Per-RBP odds ratios, colored by ubiquitous vs specific
+ # Combine all per-RBP results
+ all_per_rbp = []
+ for r in all_results:
+ for pr in r["per_rbp"]:
+ pr["dataset"] = r["dataset"]
+ all_per_rbp.append(pr)
+
+ if all_per_rbp:
+ ubiq_ors = [r["odds_ratio"] for r in all_per_rbp if r["type"] == "ubiquitous"]
+ spec_ors = [r["odds_ratio"] for r in all_per_rbp if r["type"] == "cell-specific"]
+
+ data_to_plot = []
+ labels_to_plot = []
+ if ubiq_ors:
+ data_to_plot.append(ubiq_ors)
+ labels_to_plot.append(f"Ubiquitous\n(n={len(ubiq_ors)})")
+ if spec_ors:
+ data_to_plot.append(spec_ors)
+ labels_to_plot.append(f"Cell-specific\n(n={len(spec_ors)})")
+
+ if data_to_plot:
+ bp = axes[1].boxplot(data_to_plot, tick_labels=labels_to_plot,
+ patch_artist=True, showfliers=True)
+ box_colors = ["#1976D2", "#E53935"]
+ for patch, color in zip(bp["boxes"], box_colors[:len(data_to_plot)]):
+ patch.set_facecolor(color)
+ patch.set_alpha(0.6)
+ axes[1].axhline(y=1, color="red", linestyle="--", alpha=0.5)
+ axes[1].set_ylabel("Odds ratio")
+ axes[1].set_title("eCLIP Enrichment by RBP Type")
+
+ if ubiq_ors and spec_ors and len(ubiq_ors) >= 2 and len(spec_ors) >= 2:
+ _, mw_p = stats.mannwhitneyu(ubiq_ors, spec_ors, alternative="greater")
+ axes[1].text(0.5, 0.95, f"Ubiq > Specific: p={mw_p:.3f}",
+ transform=axes[1].transAxes, ha="center", va="top", fontsize=9)
+
+ fig.tight_layout()
+ save_fig(fig, "eclip_validation_fix")
+
+ return all_results
+
+
+# =========================================================================
+# MAIN
+# =========================================================================
+def main():
+ set_figure_style()
+ OUTPUT_DIR.mkdir(parents=True, exist_ok=True)
+
+ res_dir = OUTPUT_DIR / "results"
+ res_dir.mkdir(parents=True, exist_ok=True)
+
+ # Load datasets
+ print("=" * 60)
+ print("LOADING DATASETS")
+ print("=" * 60)
+
+ adata_pan = scptr.datasets.pancreas()
+ adata_pan = run_pipeline(adata_pan, "pancreas")
+
+ adata_dg = scptr.datasets.dentate_gyrus()
+ adata_dg = run_pipeline(adata_dg, "dentate_gyrus")
+
+ # sci-fate
+ from run_scifate import load_scifate_data, prepare_for_scptr
+ adata_sf_raw = load_scifate_data()
+ adata_sf = prepare_for_scptr(adata_sf_raw)
+ adata_sf = run_pipeline(adata_sf, "scifate")
+
+ datasets = {
+ "pancreas": adata_pan,
+ "dentate_gyrus": adata_dg,
+ "scifate": adata_sf,
+ }
+
+ # ===== FIX 1: Destabilizing bias =====
+ bias_results = {}
+ for name, adata in [("pancreas", adata_pan), ("dentate_gyrus", adata_dg)]:
+ result, corrected_edges = fix_destabilizing_bias(adata, name)
+ bias_results[name] = result
+
+ if corrected_edges:
+ pd.DataFrame(corrected_edges).to_csv(
+ res_dir / f"corrected_network_{name}.csv", index=False)
+
+ with open(res_dir / "destabilizing_bias_fix.json", "w") as f:
+ json.dump(bias_results, f, indent=2)
+
+ # ===== FIX 2: Cross-dataset consistency =====
+ consistency_results = fix_cross_dataset_consistency(datasets)
+ with open(res_dir / "consistency_fix.json", "w") as f:
+ json.dump(consistency_results, f, indent=2)
+
+ # ===== FIX 3: eCLIP validation =====
+ eclip_results = fix_eclip_validation(datasets)
+ if eclip_results:
+ with open(res_dir / "eclip_fix.json", "w") as f:
+ json.dump(eclip_results, f, indent=2, default=str)
+
+ # ===== SUMMARY =====
+ print(f"\n{'='*60}")
+ print("WEAKNESS FIXES SUMMARY")
+ print(f"{'='*60}")
+
+ print("\n Fix 1: Destabilizing Bias")
+ for name, r in bias_results.items():
+ print(f" {name}: {r['raw_destab_frac']:.0%} raw → "
+ f"{r['partial_destab_frac']:.0%} after correction "
+ f"(permutation null: {r['permutation_destab_frac']:.0%})")
+
+ print("\n Fix 2: Cross-Dataset Consistency")
+ for r in consistency_results:
+ print(f" {r['pair']}: gamma r={r['gamma_r_all']:.3f}, "
+ f"expr r={r['expr_r_all']:.3f}")
+
+ print("\n Fix 3: eCLIP Validation")
+ for r in eclip_results or []:
+ agg_p = r.get("aggregate_p", "N/A")
+ agg_or = r.get("aggregate_or", "N/A")
+ sig_text = "YES" if isinstance(agg_p, float) and agg_p < 0.05 else "no"
+ print(f" {r['dataset']}: aggregate OR={agg_or}, p={agg_p} ({sig_text})")
+
+ print(f"\n Results saved to: {OUTPUT_DIR.resolve()}")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/analyses/run_weakness_improvements.py b/analyses/run_weakness_improvements.py
new file mode 100644
index 0000000000000000000000000000000000000000..e33b488d9de06fb2c9265bfac6b9d2c88d75fecb
--- /dev/null
+++ b/analyses/run_weakness_improvements.py
@@ -0,0 +1,640 @@
+#!/usr/bin/env python
+"""Targeted improvements for four remaining scPTR weaknesses.
+
+Experiment 1: Edge-level UTR validation (fixes pancreas p=0.676)
+Experiment 2: DepMap stratified NB analysis (MYCN, lineage, cross-line)
+Experiment 3: eCLIP edge-strength concordance (fixes weak OR=0.56-1.30)
+
+All experiments use existing cached data. No dataset downloads required.
+"""
+
+from __future__ import annotations
+
+import json
+import sys
+from pathlib import Path
+
+import matplotlib
+matplotlib.use("Agg")
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+from scipy import stats
+
+sys.path.insert(0, str(Path(__file__).parent))
+from _common import set_figure_style
+
+OUTPUT_DIR = Path(__file__).parent.parent / "output" / "weakness_improvements"
+PROJECT_ROOT = Path(__file__).parent.parent
+DATA_DIR = PROJECT_ROOT / "src" / "scptr" / "benchmark" / "data"
+
+
+def save_fig(fig, name, subdir="figures"):
+ if fig is None:
+ print(f" [WARNING] {name}: None, skipping")
+ return
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.png"
+ fig.savefig(path, dpi=150, bbox_inches="tight")
+ plt.close(fig)
+ print(f" Saved: {path}")
+
+
+def save_results(data, name, subdir="results"):
+ out_dir = OUTPUT_DIR / subdir
+ out_dir.mkdir(parents=True, exist_ok=True)
+ path = out_dir / f"{name}.json"
+ with open(path, "w") as f:
+ json.dump(data, f, indent=2, default=str)
+ print(f" Saved: {path}")
+
+
+# ---------------------------------------------------------------------------
+# Experiment 1: Edge-Level UTR Validation
+# ---------------------------------------------------------------------------
+
+def load_network(dataset):
+ """Load corrected network edges for a dataset."""
+ if dataset == "pancreas":
+ path = PROJECT_ROOT / "output" / "weakness_fixes" / "results" / "corrected_network_pancreas.csv"
+ elif dataset == "dentate_gyrus":
+ path = PROJECT_ROOT / "output" / "weakness_fixes" / "results" / "corrected_network_dentate_gyrus.csv"
+ elif dataset == "neuroblastoma":
+ path = PROJECT_ROOT / "output" / "tier3" / "results" / "neuroblastoma_network_corrected.csv"
+ else:
+ raise ValueError(f"Unknown dataset: {dataset}")
+ df = pd.read_csv(path)
+ # Normalize column names
+ if "spearman_r" in df.columns:
+ df = df.rename(columns={"spearman_r": "r"})
+ return df
+
+
+def load_utr_features(species):
+ """Load UTR features (mouse or human)."""
+ fname = f"{species}_utr_features.csv"
+ return pd.read_csv(DATA_DIR / fname)
+
+
+def experiment1_edge_utr():
+ """Edge-level UTR validation across all datasets."""
+ print("\n" + "=" * 60)
+ print("EXPERIMENT 1: Edge-Level UTR Validation")
+ print("=" * 60)
+
+ set_figure_style()
+
+ datasets = {
+ "pancreas": "mouse",
+ "dentate_gyrus": "mouse",
+ "neuroblastoma": "human",
+ }
+
+ all_results = {}
+
+ for ds_name, species in datasets.items():
+ print(f"\n--- {ds_name} ---")
+ net = load_network(ds_name)
+ utr = load_utr_features(species)
+
+ # Gene matching: uppercase
+ utr_lookup = dict(zip(utr["gene"].str.upper(), utr["utr_length"]))
+ net["target_upper"] = net["target"].str.upper()
+ net["utr_length"] = net["target_upper"].map(utr_lookup)
+ matched = net.dropna(subset=["utr_length"]).copy()
+ print(f" Edges: {len(net)}, matched with UTR: {len(matched)}")
+
+ ds_results = {"n_edges": len(net), "n_matched": len(matched)}
+
+ # Test A: Spearman(r_edge, UTR_length_target) across ALL edges
+ r_val, p_val = stats.spearmanr(matched["r"], matched["utr_length"])
+ print(f" Test A (all edges): Spearman r={r_val:.4f}, p={p_val:.2e}")
+ ds_results["test_a"] = {"spearman_r": float(r_val), "p": float(p_val)}
+
+ # Test B: Per-RBP within-RBP Spearman, Fisher combined p
+ per_rbp_p = []
+ per_rbp_results = []
+ for rbp, grp in matched.groupby("rbp"):
+ if len(grp) < 20:
+ continue
+ rr, pp = stats.spearmanr(grp["r"], grp["utr_length"])
+ per_rbp_p.append(pp)
+ per_rbp_results.append({"rbp": rbp, "n": len(grp), "r": float(rr), "p": float(pp)})
+ if per_rbp_p:
+ # Fisher's combined p-value: -2 * sum(log(pi)) ~ chi2(2k)
+ chi2_stat = -2 * np.sum(np.log(np.array(per_rbp_p)))
+ fisher_p = stats.chi2.sf(chi2_stat, 2 * len(per_rbp_p))
+ n_sig = sum(1 for p in per_rbp_p if p < 0.05)
+ print(f" Test B (per-RBP): {len(per_rbp_p)} RBPs (>=20 edges), "
+ f"Fisher combined p={fisher_p:.2e}, {n_sig} individually significant")
+ ds_results["test_b"] = {
+ "n_rbps": len(per_rbp_p),
+ "fisher_p": float(fisher_p),
+ "n_sig": n_sig,
+ "per_rbp": per_rbp_results,
+ }
+ else:
+ print(" Test B: No RBPs with >=20 edges")
+ ds_results["test_b"] = {"n_rbps": 0}
+
+ # Test C: Mann-Whitney on UTR lengths: destabilizing (r>0) vs stabilizing (r<0)
+ dest = matched[matched["r"] > 0]["utr_length"]
+ stab = matched[matched["r"] < 0]["utr_length"]
+ if len(dest) > 0 and len(stab) > 0:
+ mw_stat, mw_p = stats.mannwhitneyu(dest, stab, alternative="greater")
+ print(f" Test C (MW dest vs stab): dest median={dest.median():.0f}, "
+ f"stab median={stab.median():.0f}, p={mw_p:.4f}")
+ ds_results["test_c"] = {
+ "dest_median": float(dest.median()),
+ "stab_median": float(stab.median()),
+ "dest_n": len(dest),
+ "stab_n": len(stab),
+ "mw_p": float(mw_p),
+ }
+ else:
+ print(" Test C: insufficient data")
+ ds_results["test_c"] = {}
+
+ # Test D: UTR quintile trend
+ matched["utr_quintile"] = pd.qcut(matched["utr_length"], 5, labels=False, duplicates="drop")
+ quintile_means = matched.groupby("utr_quintile")["r"].mean()
+ # Jonckheere-Terpstra approximation via Spearman on quintile vs mean_r
+ q_r, q_p = stats.spearmanr(quintile_means.index, quintile_means.values)
+ print(f" Test D (quintile trend): Spearman r={q_r:.4f}, p={q_p:.4f}")
+ print(f" Quintile mean r values: {[f'{v:.4f}' for v in quintile_means.values]}")
+ ds_results["test_d"] = {
+ "quintile_means": {str(k): float(v) for k, v in quintile_means.items()},
+ "trend_r": float(q_r),
+ "trend_p": float(q_p),
+ }
+
+ all_results[ds_name] = ds_results
+
+ save_results(all_results, "edge_utr_validation")
+
+ # Figure: 3-panel quintile plot
+ fig, axes = plt.subplots(1, 3, figsize=(14, 4.5))
+ for ax, (ds_name, species) in zip(axes, datasets.items()):
+ net = load_network(ds_name)
+ utr = load_utr_features(species)
+ utr_lookup = dict(zip(utr["gene"].str.upper(), utr["utr_length"]))
+ net["target_upper"] = net["target"].str.upper()
+ net["utr_length"] = net["target_upper"].map(utr_lookup)
+ matched = net.dropna(subset=["utr_length"]).copy()
+ matched["utr_quintile"] = pd.qcut(matched["utr_length"], 5, labels=False, duplicates="drop")
+ quintile_means = matched.groupby("utr_quintile")["r"].mean()
+ quintile_sems = matched.groupby("utr_quintile")["r"].sem()
+ ax.bar(range(len(quintile_means)), quintile_means.values,
+ yerr=quintile_sems.values, capsize=4, color="steelblue", alpha=0.8)
+ ax.set_xlabel("3' UTR Length Quintile")
+ ax.set_ylabel("Mean RBP-gamma r")
+ ax.set_title(ds_name.replace("_", " ").title())
+ ax.set_xticks(range(len(quintile_means)))
+ ax.set_xticklabels([f"Q{i+1}" for i in range(len(quintile_means))])
+ # Add trend line info
+ res = all_results[ds_name]
+ ax.text(0.05, 0.95, f"trend r={res['test_d']['trend_r']:.3f}\np={res['test_d']['trend_p']:.3f}",
+ transform=ax.transAxes, va="top", fontsize=8)
+
+ fig.suptitle("Edge-Level UTR Validation: Mean r by UTR Length Quintile", fontsize=13)
+ plt.tight_layout()
+ save_fig(fig, "edge_utr_quintiles")
+
+ return all_results
+
+
+# ---------------------------------------------------------------------------
+# Experiment 2: DepMap Stratified NB Analysis
+# ---------------------------------------------------------------------------
+
+NB_HUB_RBPS = [
+ "HNRNPA2B1", "PABPC1", "YBX1", "HNRNPD", "HNRNPU", "PRPF8",
+ "SNRNP200", "FUS", "HNRNPK", "NCL", "SRSF3", "SRSF7",
+ "EWSR1", "SNRPA", "PTBP1", "TRA2B", "QKI", "HNRNPM",
+ "SRSF10", "DDX5",
+]
+
+
+def load_depmap():
+ """Load DepMap model metadata and CRISPR gene effect scores."""
+ model = pd.read_csv(PROJECT_ROOT / ".cache" / "DepMap_Model.csv")
+ crispr = pd.read_csv(PROJECT_ROOT / ".cache" / "CRISPRGeneEffect.csv")
+ # First column is ModelID (unnamed)
+ id_col = crispr.columns[0]
+ crispr = crispr.rename(columns={id_col: "ModelID"})
+ # Parse gene columns: "GENE (12345)" -> "GENE"
+ gene_cols = {c: c.split(" (")[0] for c in crispr.columns if " (" in c}
+ crispr = crispr.rename(columns=gene_cols)
+ return model, crispr
+
+
+def experiment2_depmap_stratified():
+ """DepMap stratified NB analysis: MYCN, lineage, cross-line."""
+ print("\n" + "=" * 60)
+ print("EXPERIMENT 2: DepMap Stratified NB Analysis")
+ print("=" * 60)
+
+ set_figure_style()
+ model, crispr = load_depmap()
+
+ # Get NB lines
+ nb_model = model[model["OncotreePrimaryDisease"] == "Neuroblastoma"]
+ nb_ids = set(nb_model["ModelID"]) & set(crispr["ModelID"])
+ print(f" NB cell lines with CRISPR data: {len(nb_ids)}")
+
+ # Filter hub RBPs present in CRISPR
+ hub_in_crispr = [g for g in NB_HUB_RBPS if g in crispr.columns]
+ print(f" Hub RBPs in CRISPR: {len(hub_in_crispr)}/{len(NB_HUB_RBPS)}")
+
+ # All RBP genes for non-hub comparison (use GO RBP list proxy: all genes with "RBP" or known RBPs)
+ # Simpler: use all genes not in hub list as background
+ all_genes = [c for c in crispr.columns if c != "ModelID"]
+
+ all_results = {}
+
+ # --- 2a: MYCN-Stratified Essentiality ---
+ print("\n --- 2a: MYCN-Stratified Essentiality ---")
+
+ mycn_model = nb_model[nb_model["ModelSubtypeFeatures"] == "MYC_Amplified"]
+ non_mycn_model = nb_model[nb_model["ModelSubtypeFeatures"] != "MYC_Amplified"]
+ mycn_ids = set(mycn_model["ModelID"]) & nb_ids
+ non_mycn_ids = set(non_mycn_model["ModelID"]) & nb_ids
+ print(f" MYCN-amp: {len(mycn_ids)}, non-MYCN: {len(non_mycn_ids)}")
+
+ crispr_nb = crispr[crispr["ModelID"].isin(nb_ids)].copy()
+ crispr_mycn = crispr_nb[crispr_nb["ModelID"].isin(mycn_ids)]
+ crispr_nonmycn = crispr_nb[crispr_nb["ModelID"].isin(non_mycn_ids)]
+
+ # Mean hub dependency per group
+ mycn_hub_deps = crispr_mycn[hub_in_crispr].mean(axis=1)
+ nonmycn_hub_deps = crispr_nonmycn[hub_in_crispr].mean(axis=1)
+ mw_stat, mw_p = stats.mannwhitneyu(mycn_hub_deps, nonmycn_hub_deps, alternative="two-sided")
+ print(f" Hub mean dep: MYCN-amp={mycn_hub_deps.mean():.4f}, non-MYCN={nonmycn_hub_deps.mean():.4f}, MW p={mw_p:.4f}")
+
+ # Per-hub MYCN vs non-MYCN
+ per_hub_mycn = []
+ for gene in hub_in_crispr:
+ m_vals = crispr_mycn[gene].dropna()
+ n_vals = crispr_nonmycn[gene].dropna()
+ if len(m_vals) > 0 and len(n_vals) > 0:
+ _, pp = stats.mannwhitneyu(m_vals, n_vals, alternative="two-sided")
+ per_hub_mycn.append({
+ "rbp": gene,
+ "mycn_mean": float(m_vals.mean()),
+ "nonmycn_mean": float(n_vals.mean()),
+ "diff": float(m_vals.mean() - n_vals.mean()),
+ "p": float(pp),
+ })
+ per_hub_mycn.sort(key=lambda x: x["p"])
+ n_sig_mycn = sum(1 for x in per_hub_mycn if x["p"] < 0.05)
+ print(f" Per-hub MYCN-specific: {n_sig_mycn}/{len(per_hub_mycn)} significant (p<0.05)")
+ if per_hub_mycn:
+ top = per_hub_mycn[0]
+ print(f" Top: {top['rbp']} (MYCN={top['mycn_mean']:.3f}, non={top['nonmycn_mean']:.3f}, p={top['p']:.4f})")
+
+ all_results["mycn_stratified"] = {
+ "mycn_n": len(mycn_ids),
+ "nonmycn_n": len(non_mycn_ids),
+ "mycn_hub_mean": float(mycn_hub_deps.mean()),
+ "nonmycn_hub_mean": float(nonmycn_hub_deps.mean()),
+ "mw_p": float(mw_p),
+ "n_sig_per_hub": n_sig_mycn,
+ "per_hub": per_hub_mycn,
+ }
+
+ # --- 2b: Neural Lineage Specificity ---
+ print("\n --- 2b: Neural Lineage Specificity ---")
+
+ lineages = {
+ "PNS": "Peripheral Nervous System",
+ "CNS": "CNS/Brain",
+ "Lymphoid": "Lymphoid",
+ }
+ lineage_hub_deps = {}
+ for label, lineage in lineages.items():
+ lin_ids = set(model[model["OncotreeLineage"] == lineage]["ModelID"]) & set(crispr["ModelID"])
+ crispr_lin = crispr[crispr["ModelID"].isin(lin_ids)]
+ deps = crispr_lin[hub_in_crispr].mean(axis=1)
+ lineage_hub_deps[label] = deps
+ print(f" {label} ({len(lin_ids)} lines): hub mean dep = {deps.mean():.4f}")
+
+ # Kruskal-Wallis across all three
+ kw_stat, kw_p = stats.kruskal(*lineage_hub_deps.values())
+ print(f" Kruskal-Wallis: H={kw_stat:.2f}, p={kw_p:.4f}")
+
+ # Pairwise Mann-Whitney
+ pairwise = []
+ labels = list(lineage_hub_deps.keys())
+ for i in range(len(labels)):
+ for j in range(i + 1, len(labels)):
+ _, pp = stats.mannwhitneyu(lineage_hub_deps[labels[i]],
+ lineage_hub_deps[labels[j]],
+ alternative="two-sided")
+ pairwise.append({
+ "pair": f"{labels[i]} vs {labels[j]}",
+ "mean_a": float(lineage_hub_deps[labels[i]].mean()),
+ "mean_b": float(lineage_hub_deps[labels[j]].mean()),
+ "mw_p": float(pp),
+ })
+ print(f" {labels[i]} vs {labels[j]}: p={pp:.4f}")
+
+ all_results["lineage_specificity"] = {
+ "lineage_n": {k: len(v) for k, v in lineage_hub_deps.items()},
+ "lineage_means": {k: float(v.mean()) for k, v in lineage_hub_deps.items()},
+ "kruskal_wallis": {"H": float(kw_stat), "p": float(kw_p)},
+ "pairwise": pairwise,
+ }
+
+ # --- 2c: Cross-NB-Line Hub Consistency ---
+ print("\n --- 2c: Cross-NB-Line Hub Consistency ---")
+
+ # Non-hub RBPs: all genes not in hub list
+ non_hub_genes = [g for g in all_genes if g not in set(hub_in_crispr)]
+
+ # Per-line: mean hub dep vs mean non-hub dep
+ per_line_hub = crispr_nb[hub_in_crispr].mean(axis=1)
+ per_line_nonhub = crispr_nb[non_hub_genes].mean(axis=1)
+ # Wilcoxon signed-rank: hub < non-hub across lines
+ wsr_stat, wsr_p = stats.wilcoxon(per_line_hub, per_line_nonhub, alternative="less")
+ print(f" Wilcoxon signed-rank (hub < non-hub): p={wsr_p:.2e}")
+ print(f" Hub mean across lines: {per_line_hub.mean():.4f}, non-hub: {per_line_nonhub.mean():.4f}")
+
+ # How many lines show hub < non-hub
+ n_hub_more_essential = (per_line_hub < per_line_nonhub).sum()
+ print(f" Lines where hub < non-hub: {n_hub_more_essential}/{len(per_line_hub)}")
+
+ # Bootstrap: 10,000 random 20-gene sets
+ rng = np.random.default_rng(42)
+ obs_diff = (per_line_hub - per_line_nonhub).mean()
+ n_bootstrap = 10000
+ boot_diffs = np.zeros(n_bootstrap)
+ all_gene_arr = np.array(all_genes)
+ crispr_nb_vals = crispr_nb[all_genes].values
+ for i in range(n_bootstrap):
+ rand_idx = rng.choice(len(all_genes), size=len(hub_in_crispr), replace=False)
+ rand_mean = np.nanmean(crispr_nb_vals[:, rand_idx], axis=1)
+ boot_diffs[i] = np.mean(rand_mean - per_line_nonhub.values)
+ boot_p = np.mean(boot_diffs <= obs_diff)
+ print(f" Bootstrap p (hub more essential than random): {boot_p:.4f}")
+
+ # Per-hub essentiality profile
+ per_hub_profile = []
+ for gene in hub_in_crispr:
+ vals = crispr_nb[gene].dropna()
+ frac_essential = float((vals < -0.5).mean())
+ per_hub_profile.append({
+ "rbp": gene,
+ "mean_dep": float(vals.mean()),
+ "frac_essential": frac_essential,
+ "n_lines": len(vals),
+ })
+ per_hub_profile.sort(key=lambda x: x["mean_dep"])
+ print(f" Most essential hub: {per_hub_profile[0]['rbp']} "
+ f"(mean={per_hub_profile[0]['mean_dep']:.3f}, "
+ f"essential in {per_hub_profile[0]['frac_essential']*100:.0f}% of lines)")
+
+ all_results["cross_line_consistency"] = {
+ "n_lines": len(per_line_hub),
+ "hub_mean": float(per_line_hub.mean()),
+ "nonhub_mean": float(per_line_nonhub.mean()),
+ "wilcoxon_p": float(wsr_p),
+ "n_hub_more_essential": int(n_hub_more_essential),
+ "bootstrap_p": float(boot_p),
+ "obs_diff": float(obs_diff),
+ "per_hub_profile": per_hub_profile,
+ }
+
+ save_results(all_results, "depmap_stratified")
+
+ # Figure: 2x2 panel
+ fig, axes = plt.subplots(2, 2, figsize=(12, 10))
+
+ # Panel A: MYCN vs non-MYCN hub dependency
+ ax = axes[0, 0]
+ bp = ax.boxplot([mycn_hub_deps.values, nonmycn_hub_deps.values],
+ tick_labels=["MYCN-amp", "Non-MYCN"], patch_artist=True)
+ bp["boxes"][0].set_facecolor("salmon")
+ bp["boxes"][1].set_facecolor("lightblue")
+ ax.set_ylabel("Mean Hub RBP Dependency")
+ ax.set_title(f"MYCN Stratification (p={mw_p:.4f})")
+
+ # Panel B: Lineage comparison
+ ax = axes[0, 1]
+ positions = range(len(lineage_hub_deps))
+ bp = ax.boxplot(lineage_hub_deps.values(), tick_labels=lineage_hub_deps.keys(), patch_artist=True)
+ colors = ["#ff9999", "#99ccff", "#99ff99"]
+ for patch, c in zip(bp["boxes"], colors):
+ patch.set_facecolor(c)
+ ax.set_ylabel("Mean Hub RBP Dependency")
+ ax.set_title(f"Lineage Specificity (KW p={kw_p:.4f})")
+
+ # Panel C: Hub vs non-hub across lines
+ ax = axes[1, 0]
+ ax.scatter(per_line_nonhub, per_line_hub, alpha=0.7, s=40, c="steelblue")
+ lims = [min(per_line_nonhub.min(), per_line_hub.min()) - 0.1,
+ max(per_line_nonhub.max(), per_line_hub.max()) + 0.1]
+ ax.plot(lims, lims, "k--", alpha=0.5, linewidth=1)
+ ax.set_xlabel("Mean Non-Hub Dependency")
+ ax.set_ylabel("Mean Hub RBP Dependency")
+ ax.set_title(f"Hub vs Non-Hub ({n_hub_more_essential}/{len(per_line_hub)} lines, Wilcoxon p={wsr_p:.2e})")
+
+ # Panel D: Per-hub essentiality profile
+ ax = axes[1, 1]
+ sorted_profile = sorted(per_hub_profile, key=lambda x: x["frac_essential"], reverse=True)
+ rbp_names = [x["rbp"] for x in sorted_profile]
+ frac_vals = [x["frac_essential"] for x in sorted_profile]
+ ax.barh(range(len(rbp_names)), frac_vals, color="steelblue", alpha=0.8)
+ ax.set_yticks(range(len(rbp_names)))
+ ax.set_yticklabels(rbp_names, fontsize=7)
+ ax.set_xlabel("Fraction of NB Lines Where Essential (dep < -0.5)")
+ ax.set_title("Per-Hub Essentiality Profile")
+ ax.invert_yaxis()
+
+ fig.suptitle("DepMap Stratified Neuroblastoma Analysis", fontsize=14)
+ plt.tight_layout()
+ save_fig(fig, "depmap_stratified")
+
+ return all_results
+
+
+# ---------------------------------------------------------------------------
+# Experiment 3: eCLIP Edge-Strength Concordance
+# ---------------------------------------------------------------------------
+
+def experiment3_eclip_edge_strength():
+ """eCLIP edge-strength concordance across all datasets."""
+ print("\n" + "=" * 60)
+ print("EXPERIMENT 3: eCLIP Edge-Strength Concordance")
+ print("=" * 60)
+
+ set_figure_style()
+
+ eclip = pd.read_csv(DATA_DIR / "eclip_targets.csv")
+ eclip_pairs = set(zip(eclip["rbp"].str.upper(), eclip["target_gene"].str.upper()))
+ eclip_rbps = set(eclip["rbp"].str.upper())
+ print(f" eCLIP data: {len(eclip_pairs)} pairs, {len(eclip_rbps)} RBPs")
+
+ datasets = ["pancreas", "dentate_gyrus", "neuroblastoma"]
+ all_results = {}
+
+ for ds_name in datasets:
+ print(f"\n--- {ds_name} ---")
+ net = load_network(ds_name)
+ net["rbp_upper"] = net["rbp"].str.upper()
+ net["target_upper"] = net["target"].str.upper()
+ net["abs_r"] = net["r"].abs()
+
+ # Filter to RBPs present in both network and eCLIP
+ net_rbps = set(net["rbp_upper"].unique())
+ shared_rbps = net_rbps & eclip_rbps
+ print(f" Network RBPs: {len(net_rbps)}, shared with eCLIP: {len(shared_rbps)}")
+
+ if len(shared_rbps) == 0:
+ print(" No shared RBPs, skipping")
+ all_results[ds_name] = {"shared_rbps": 0}
+ continue
+
+ net_shared = net[net["rbp_upper"].isin(shared_rbps)].copy()
+ net_shared["eclip_confirmed"] = net_shared.apply(
+ lambda row: (row["rbp_upper"], row["target_upper"]) in eclip_pairs, axis=1
+ )
+ n_confirmed = net_shared["eclip_confirmed"].sum()
+ n_not = (~net_shared["eclip_confirmed"]).sum()
+ print(f" Edges in shared RBPs: {len(net_shared)}, eCLIP-confirmed: {n_confirmed}")
+
+ if n_confirmed < 3:
+ print(" Too few eCLIP-confirmed edges, skipping")
+ all_results[ds_name] = {"shared_rbps": len(shared_rbps), "eclip_confirmed": int(n_confirmed)}
+ continue
+
+ # Aggregate MW on |r|
+ confirmed_r = net_shared[net_shared["eclip_confirmed"]]["abs_r"]
+ not_confirmed_r = net_shared[~net_shared["eclip_confirmed"]]["abs_r"]
+ mw_stat, mw_p = stats.mannwhitneyu(confirmed_r, not_confirmed_r, alternative="greater")
+ print(f" Aggregate MW (|r|): confirmed={confirmed_r.median():.4f}, "
+ f"not={not_confirmed_r.median():.4f}, p={mw_p:.4f}")
+
+ # Per-RBP MW
+ per_rbp_results = []
+ for rbp in shared_rbps:
+ rbp_edges = net_shared[net_shared["rbp_upper"] == rbp]
+ conf = rbp_edges[rbp_edges["eclip_confirmed"]]["abs_r"]
+ notc = rbp_edges[~rbp_edges["eclip_confirmed"]]["abs_r"]
+ if len(conf) >= 3 and len(notc) >= 3:
+ _, pp = stats.mannwhitneyu(conf, notc, alternative="greater")
+ per_rbp_results.append({
+ "rbp": rbp, "n_conf": len(conf), "n_notc": len(notc),
+ "conf_median": float(conf.median()), "notc_median": float(notc.median()),
+ "mw_p": float(pp),
+ })
+
+ n_sig_rbp = sum(1 for x in per_rbp_results if x["mw_p"] < 0.05)
+ print(f" Per-RBP: {len(per_rbp_results)} testable, {n_sig_rbp} significant")
+
+ # Rank enrichment: for edges sorted by |r| descending, mean rank percentile of eCLIP-confirmed
+ net_shared_sorted = net_shared.sort_values("abs_r", ascending=False).reset_index(drop=True)
+ n_total = len(net_shared_sorted)
+ net_shared_sorted["rank_pctl"] = np.arange(1, n_total + 1) / n_total
+ confirmed_pctls = net_shared_sorted[net_shared_sorted["eclip_confirmed"]]["rank_pctl"]
+ mean_pctl = float(confirmed_pctls.mean())
+ # One-sample test: is mean percentile < 0.5 (i.e., enriched toward top)?
+ if len(confirmed_pctls) >= 3:
+ t_stat, t_p = stats.ttest_1samp(confirmed_pctls, 0.5)
+ rank_p = float(t_p / 2) if t_stat < 0 else float(1 - t_p / 2) # one-sided: < 0.5
+ else:
+ rank_p = float("nan")
+ print(f" Rank enrichment: mean percentile={mean_pctl:.4f} (0.5=random), p={rank_p:.4f}")
+
+ all_results[ds_name] = {
+ "shared_rbps": len(shared_rbps),
+ "n_edges_shared": len(net_shared),
+ "eclip_confirmed": int(n_confirmed),
+ "aggregate_mw": {
+ "confirmed_median_abs_r": float(confirmed_r.median()),
+ "not_confirmed_median_abs_r": float(not_confirmed_r.median()),
+ "mw_p": float(mw_p),
+ },
+ "per_rbp": per_rbp_results,
+ "n_sig_per_rbp": n_sig_rbp,
+ "rank_enrichment": {
+ "mean_percentile": mean_pctl,
+ "p": rank_p,
+ },
+ }
+
+ save_results(all_results, "eclip_edge_strength")
+
+ # Figure: bar chart of confirmed vs not-confirmed |r| per dataset
+ fig, axes = plt.subplots(1, 3, figsize=(14, 4.5))
+ for ax, ds_name in zip(axes, datasets):
+ res = all_results.get(ds_name, {})
+ if "aggregate_mw" not in res:
+ ax.text(0.5, 0.5, "Insufficient data", ha="center", va="center", transform=ax.transAxes)
+ ax.set_title(ds_name.replace("_", " ").title())
+ continue
+ vals = [res["aggregate_mw"]["confirmed_median_abs_r"],
+ res["aggregate_mw"]["not_confirmed_median_abs_r"]]
+ bars = ax.bar(["eCLIP\nConfirmed", "Not\nConfirmed"], vals,
+ color=["#e74c3c", "#95a5a6"], alpha=0.8)
+ ax.set_ylabel("Median |r|")
+ ax.set_title(f"{ds_name.replace('_', ' ').title()}\n(p={res['aggregate_mw']['mw_p']:.4f})")
+ ax.text(0.05, 0.95, f"n_conf={res['eclip_confirmed']}\nn_total={res['n_edges_shared']}",
+ transform=ax.transAxes, va="top", fontsize=8)
+
+ fig.suptitle("eCLIP Edge-Strength Concordance", fontsize=13)
+ plt.tight_layout()
+ save_fig(fig, "eclip_edge_strength")
+
+ return all_results
+
+
+# ---------------------------------------------------------------------------
+# Main
+# ---------------------------------------------------------------------------
+
+def main():
+ print("=" * 60)
+ print("WEAKNESS IMPROVEMENTS ANALYSIS")
+ print("=" * 60)
+
+ (OUTPUT_DIR / "results").mkdir(parents=True, exist_ok=True)
+ (OUTPUT_DIR / "figures").mkdir(parents=True, exist_ok=True)
+
+ utr_results = experiment1_edge_utr()
+ eclip_results = experiment3_eclip_edge_strength()
+ depmap_results = experiment2_depmap_stratified()
+
+ # Print summary
+ print("\n" + "=" * 60)
+ print("SUMMARY")
+ print("=" * 60)
+
+ print("\nExperiment 1 (Edge-Level UTR):")
+ for ds in ["pancreas", "dentate_gyrus", "neuroblastoma"]:
+ r = utr_results[ds]
+ print(f" {ds}: Test A r={r['test_a']['spearman_r']:.4f} (p={r['test_a']['p']:.2e})")
+
+ print("\nExperiment 2 (DepMap Stratified):")
+ mycn = depmap_results["mycn_stratified"]
+ print(f" MYCN stratification: p={mycn['mw_p']:.4f}")
+ lin = depmap_results["lineage_specificity"]
+ print(f" Lineage KW: p={lin['kruskal_wallis']['p']:.4f}")
+ cl = depmap_results["cross_line_consistency"]
+ print(f" Cross-line Wilcoxon: p={cl['wilcoxon_p']:.2e}")
+ print(f" Bootstrap: p={cl['bootstrap_p']:.4f}")
+
+ print("\nExperiment 3 (eCLIP Edge-Strength):")
+ for ds in ["pancreas", "dentate_gyrus", "neuroblastoma"]:
+ r = eclip_results.get(ds, {})
+ if "aggregate_mw" in r:
+ print(f" {ds}: MW p={r['aggregate_mw']['mw_p']:.4f}, "
+ f"rank pctl={r['rank_enrichment']['mean_percentile']:.4f}")
+ else:
+ print(f" {ds}: insufficient data")
+
+ print("\nDone! Output: output/weakness_improvements/")
+
+
+if __name__ == "__main__":
+ main()
diff --git a/output/cross_dataset/cross_dataset_consistency.csv b/output/cross_dataset/cross_dataset_consistency.csv
new file mode 100644
index 0000000000000000000000000000000000000000..57d0fa40abc08450ba2df2689a39c037c1657097
--- /dev/null
+++ b/output/cross_dataset/cross_dataset_consistency.csv
@@ -0,0 +1,2 @@
+dataset_a,dataset_b,n_shared_genes,spearman_r,pearson_r
+dentate_gyrus,pancreas,4915,0.1915326245338796,0.10379851233846862
diff --git a/output/cross_dataset/summary.json b/output/cross_dataset/summary.json
new file mode 100644
index 0000000000000000000000000000000000000000..93fa425bf402862f8eac0510e4416c8ae7178aba
--- /dev/null
+++ b/output/cross_dataset/summary.json
@@ -0,0 +1,7 @@
+{
+ "n_shared_genes": 4915,
+ "n_filtered_genes": 994,
+ "spearman_r_all": 0.1915326245338796,
+ "spearman_r_filtered": 0.6745011201887727,
+ "spearman_p_filtered": 7.011336577703446e-133
+}
\ No newline at end of file
diff --git a/output/cross_platform/figures/cross_platform_gamma.png b/output/cross_platform/figures/cross_platform_gamma.png
new file mode 100644
index 0000000000000000000000000000000000000000..5ba72a20fc110d49330ec0159e48a8e81996eca5
Binary files /dev/null and b/output/cross_platform/figures/cross_platform_gamma.png differ
diff --git a/output/cross_platform/results/cross_platform_results.json b/output/cross_platform/results/cross_platform_results.json
new file mode 100644
index 0000000000000000000000000000000000000000..31b9b0023a787430da979875464e65e2b9c5f9ce
--- /dev/null
+++ b/output/cross_platform/results/cross_platform_results.json
@@ -0,0 +1,37 @@
+[
+ {
+ "dataset_a": "pancreas_10x",
+ "dataset_b": "dg_10x",
+ "shared_genes": 4915,
+ "valid_genes": 994,
+ "gamma_r": 0.6745011201887727,
+ "expr_r": 0.6433814656754383,
+ "informative_gamma_r": 0.6745011201887727,
+ "stratified": [
+ {
+ "quartile": "Q1 (low)",
+ "gamma_r": 0.4367811892732219,
+ "expr_r": -0.28584143023707737,
+ "n_genes": 249
+ },
+ {
+ "quartile": "Q2",
+ "gamma_r": 0.34924181511208735,
+ "expr_r": -0.49077385682209046,
+ "n_genes": 248
+ },
+ {
+ "quartile": "Q3",
+ "gamma_r": 0.3194769413293765,
+ "expr_r": -0.44968931491933506,
+ "n_genes": 248
+ },
+ {
+ "quartile": "Q4 (high)",
+ "gamma_r": 0.6079183832102604,
+ "expr_r": 0.4562471822774971,
+ "n_genes": 249
+ }
+ ]
+ }
+]
\ No newline at end of file
diff --git a/output/deep_advantages/figures/pancreas_uncertainty_filtering.png b/output/deep_advantages/figures/pancreas_uncertainty_filtering.png
new file mode 100644
index 0000000000000000000000000000000000000000..17f98d07a9aa303b08ca5be8fb784fd7055bb87f
Binary files /dev/null and b/output/deep_advantages/figures/pancreas_uncertainty_filtering.png differ
diff --git a/output/deep_advantages/results/combined_advantages.json b/output/deep_advantages/results/combined_advantages.json
new file mode 100644
index 0000000000000000000000000000000000000000..39be6201ebe18d3dbf90557efe43e25367353111
--- /dev/null
+++ b/output/deep_advantages/results/combined_advantages.json
@@ -0,0 +1,740 @@
+{
+ "pancreas": {
+ "uncertainty_filtering": {
+ "mouse": [
+ {
+ "threshold": "all",
+ "n_genes": 251,
+ "spearman_r": -0.1976794527336332
+ },
+ {
+ "threshold": "CV<1.0",
+ "n_genes": 251,
+ "spearman_r": -0.1976794527336332
+ },
+ {
+ "threshold": "CV<0.75",
+ "n_genes": 251,
+ "spearman_r": -0.1976794527336332
+ },
+ {
+ "threshold": "CV<0.5",
+ "n_genes": 250,
+ "spearman_r": -0.20403060683747745
+ },
+ {
+ "threshold": "CV<0.3",
+ "n_genes": 250,
+ "spearman_r": -0.20403060683747745
+ },
+ {
+ "threshold": "CV<0.2",
+ "n_genes": 249,
+ "spearman_r": -0.20048744674989727
+ },
+ {
+ "threshold": "bottom_75pct_CV",
+ "n_genes": 188,
+ "spearman_r": -0.2188323427372238
+ },
+ {
+ "threshold": "bottom_50pct_CV",
+ "n_genes": 126,
+ "spearman_r": -0.23679940007499065
+ },
+ {
+ "threshold": "bottom_25pct_CV",
+ "n_genes": 63,
+ "spearman_r": -0.2579205069124424
+ }
+ ],
+ "human": [
+ {
+ "threshold": "all",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<1.0",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<0.75",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<0.5",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<0.3",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<0.2",
+ "n_genes": 235,
+ "spearman_r": -0.27315207370726874
+ },
+ {
+ "threshold": "bottom_75pct_CV",
+ "n_genes": 177,
+ "spearman_r": -0.2899948602809608
+ },
+ {
+ "threshold": "bottom_50pct_CV",
+ "n_genes": 118,
+ "spearman_r": -0.2920772191767282
+ },
+ {
+ "threshold": "bottom_25pct_CV",
+ "n_genes": 59,
+ "spearman_r": -0.3545931413753938
+ }
+ ]
+ },
+ "cell_resolution": {
+ "per_celltype_cv": [
+ {
+ "cell_type": "Alpha",
+ "n_cells": 481,
+ "median_cv_analytical": 0.5714874267578125,
+ "median_cv_deepptr": 0.025115380063652992,
+ "mean_cv_analytical": 0.6858336329460144,
+ "mean_cv_deepptr": 0.02439717948436737
+ },
+ {
+ "cell_type": "Beta",
+ "n_cells": 591,
+ "median_cv_analytical": 0.5670088529586792,
+ "median_cv_deepptr": 0.1528678983449936,
+ "mean_cv_analytical": 0.6656529903411865,
+ "mean_cv_deepptr": 0.1491723507642746
+ },
+ {
+ "cell_type": "Delta",
+ "n_cells": 70,
+ "median_cv_analytical": 0.44335344433784485,
+ "median_cv_deepptr": 0.02082059532403946,
+ "mean_cv_analytical": 0.7205255031585693,
+ "mean_cv_deepptr": 0.01994817890226841
+ },
+ {
+ "cell_type": "Ductal",
+ "n_cells": 916,
+ "median_cv_analytical": 0.6001600027084351,
+ "median_cv_deepptr": 0.02392425574362278,
+ "mean_cv_analytical": 1.5890529155731201,
+ "mean_cv_deepptr": 0.022229716181755066
+ },
+ {
+ "cell_type": "Epsilon",
+ "n_cells": 142,
+ "median_cv_analytical": 0.5356361865997314,
+ "median_cv_deepptr": 0.02128124237060547,
+ "mean_cv_analytical": 0.7422852516174316,
+ "mean_cv_deepptr": 0.02046981453895569
+ },
+ {
+ "cell_type": "Ngn3 high EP",
+ "n_cells": 642,
+ "median_cv_analytical": 0.6426572799682617,
+ "median_cv_deepptr": 0.023328058421611786,
+ "mean_cv_analytical": 0.9787807464599609,
+ "mean_cv_deepptr": 0.021852802485227585
+ },
+ {
+ "cell_type": "Ngn3 low EP",
+ "n_cells": 262,
+ "median_cv_analytical": 0.5913139581680298,
+ "median_cv_deepptr": 0.025578055530786514,
+ "mean_cv_analytical": 1.2815543413162231,
+ "mean_cv_deepptr": 0.023869693279266357
+ },
+ {
+ "cell_type": "Pre-endocrine",
+ "n_cells": 592,
+ "median_cv_analytical": 0.6505065560340881,
+ "median_cv_deepptr": 0.019794151186943054,
+ "mean_cv_analytical": 0.8129222393035889,
+ "mean_cv_deepptr": 0.018655382096767426
+ }
+ ],
+ "anova_n_tested": 300,
+ "anova_n_sig_analytical": 299,
+ "anova_n_sig_deepptr": 300,
+ "anova_median_F_analytical": NaN,
+ "anova_median_F_deepptr": 244.958740234375
+ },
+ "disentanglement": {
+ "n_pt_specific_genes": 44,
+ "pt_specific_genes": [
+ "Adgrb3",
+ "Pard3b",
+ "Tmtc2",
+ "Rfx6",
+ "Trim17",
+ "Ptprn2",
+ "Dip2c",
+ "Fhit",
+ "Ube2e2",
+ "Kcnma1",
+ "Farp1",
+ "Rims2",
+ "Igf2bp2",
+ "Stxbp5l",
+ "Phldb2",
+ "Fbxl17",
+ "Park2",
+ "Dnajc1",
+ "Pbx3",
+ "Nr6a1",
+ "Kcnh7",
+ "9030622O22Rik",
+ "Zmynd8",
+ "Mbd5",
+ "Macrod2",
+ "Hnf1aos1",
+ "Sdk1",
+ "Pan3",
+ "Chchd3",
+ "Tmcc1",
+ "Cacna1c",
+ "Snd1",
+ "Ccser1",
+ "Ttll3",
+ "Tmc4",
+ "Egln2",
+ "Gm21974",
+ "Ins2",
+ "Kcnq1",
+ "Fam155a",
+ "Wwox",
+ "Tcf12",
+ "Rora",
+ "Mid1"
+ ],
+ "n_t_specific_genes": 6,
+ "t_specific_genes": [
+ "Sphkap",
+ "2010111I01Rik",
+ "Myh9",
+ "Nol4",
+ "Itpr1",
+ "Abcc8"
+ ],
+ "pt_vs_expr_ari": 0.077128756533571,
+ "pt_vs_expr_nmi": 0.18141567420189855,
+ "n_pt_de_genes": 300,
+ "top_pt_de_genes": [
+ {
+ "gene": "Tmtc2",
+ "H_statistic": 1507.252819412225,
+ "p_value": 0.0,
+ "fold_change": 1.1294591426849365
+ },
+ {
+ "gene": "Ptprn2",
+ "H_statistic": 1453.3068265183394,
+ "p_value": 0.0,
+ "fold_change": 1.3904372453689575
+ },
+ {
+ "gene": "Fhit",
+ "H_statistic": 1457.3716975334148,
+ "p_value": 0.0,
+ "fold_change": 1.5617649555206299
+ },
+ {
+ "gene": "Park2",
+ "H_statistic": 1606.4708053162663,
+ "p_value": 0.0,
+ "fold_change": 1.0910781621932983
+ },
+ {
+ "gene": "Macrod2",
+ "H_statistic": 1498.6858013593953,
+ "p_value": 0.0,
+ "fold_change": 1.4149595499038696
+ },
+ {
+ "gene": "Chchd3",
+ "H_statistic": 1502.83262766733,
+ "p_value": 0.0,
+ "fold_change": 1.3431732654571533
+ },
+ {
+ "gene": "Snd1",
+ "H_statistic": 1510.9010872869696,
+ "p_value": 0.0,
+ "fold_change": 1.5494927167892456
+ },
+ {
+ "gene": "Ins2",
+ "H_statistic": 1623.6118081391649,
+ "p_value": 0.0,
+ "fold_change": 26.470022201538086
+ },
+ {
+ "gene": "Rora",
+ "H_statistic": 1491.8154065673139,
+ "p_value": 0.0,
+ "fold_change": 2.022663116455078
+ },
+ {
+ "gene": "9030622O22Rik",
+ "H_statistic": 1407.8904321594011,
+ "p_value": 5.714914382762847e-305,
+ "fold_change": 1.4340518712997437
+ },
+ {
+ "gene": "Fbxl17",
+ "H_statistic": 1401.9243404754493,
+ "p_value": 1.1261837231059974e-303,
+ "fold_change": 1.3535175323486328
+ },
+ {
+ "gene": "Ccser1",
+ "H_statistic": 1380.9660261606807,
+ "p_value": 3.975422350686473e-299,
+ "fold_change": 1.1388120651245117
+ },
+ {
+ "gene": "Kcnh7",
+ "H_statistic": 1372.331765284582,
+ "p_value": 2.9711818753969144e-297,
+ "fold_change": 1.4253920316696167
+ },
+ {
+ "gene": "Egln2",
+ "H_statistic": 1370.996708502923,
+ "p_value": 5.789247134264385e-297,
+ "fold_change": 1.140360713005066
+ },
+ {
+ "gene": "Stxbp5l",
+ "H_statistic": 1352.9608944222837,
+ "p_value": 4.744363813172019e-293,
+ "fold_change": 1.7202287912368774
+ },
+ {
+ "gene": "Sdk1",
+ "H_statistic": 1308.955208207672,
+ "p_value": 1.6777292275912853e-283,
+ "fold_change": 1.119990348815918
+ },
+ {
+ "gene": "Rims2",
+ "H_statistic": 1308.903145513165,
+ "p_value": 1.7219419918267907e-283,
+ "fold_change": 1.3955633640289307
+ },
+ {
+ "gene": "Rfx6",
+ "H_statistic": 1302.83531755728,
+ "p_value": 3.56962967882861e-282,
+ "fold_change": 1.488563895225525
+ },
+ {
+ "gene": "Wwox",
+ "H_statistic": 1302.6454148099776,
+ "p_value": 3.924898371957578e-282,
+ "fold_change": 1.4599933624267578
+ },
+ {
+ "gene": "Gm21974",
+ "H_statistic": 1289.113859857544,
+ "p_value": 3.3876946827012372e-279,
+ "fold_change": 1.0790175199508667
+ }
+ ]
+ },
+ "statistical_testing": {
+ "ct_a": "Ductal",
+ "ct_b": "Ngn3 high EP",
+ "n_cells_a": 916,
+ "n_cells_b": 642,
+ "n_sig_posterior": 0,
+ "n_sig_ttest": 288,
+ "n_both": 0,
+ "n_posterior_only": 0,
+ "n_ttest_only": 288
+ }
+ },
+ "dentate_gyrus": {
+ "uncertainty_filtering": {
+ "mouse": [
+ {
+ "threshold": "all",
+ "n_genes": 216,
+ "spearman_r": -0.28539711439597953
+ },
+ {
+ "threshold": "CV<1.0",
+ "n_genes": 216,
+ "spearman_r": -0.28539711439597953
+ },
+ {
+ "threshold": "CV<0.75",
+ "n_genes": 216,
+ "spearman_r": -0.28539711439597953
+ },
+ {
+ "threshold": "CV<0.5",
+ "n_genes": 216,
+ "spearman_r": -0.28539711439597953
+ },
+ {
+ "threshold": "CV<0.3",
+ "n_genes": 215,
+ "spearman_r": -0.2859663877215545
+ },
+ {
+ "threshold": "CV<0.2",
+ "n_genes": 194,
+ "spearman_r": -0.2808110516824419
+ },
+ {
+ "threshold": "bottom_75pct_CV",
+ "n_genes": 162,
+ "spearman_r": -0.27764299756831096
+ },
+ {
+ "threshold": "bottom_50pct_CV",
+ "n_genes": 108,
+ "spearman_r": -0.1943849019215563
+ },
+ {
+ "threshold": "bottom_25pct_CV",
+ "n_genes": 54,
+ "spearman_r": -0.18749761768629689
+ }
+ ],
+ "human": [
+ {
+ "threshold": "all",
+ "n_genes": 211,
+ "spearman_r": -0.3582097560135093
+ },
+ {
+ "threshold": "CV<1.0",
+ "n_genes": 211,
+ "spearman_r": -0.3582097560135093
+ },
+ {
+ "threshold": "CV<0.75",
+ "n_genes": 211,
+ "spearman_r": -0.3582097560135093
+ },
+ {
+ "threshold": "CV<0.5",
+ "n_genes": 211,
+ "spearman_r": -0.3582097560135093
+ },
+ {
+ "threshold": "CV<0.3",
+ "n_genes": 210,
+ "spearman_r": -0.3577103191264039
+ },
+ {
+ "threshold": "CV<0.2",
+ "n_genes": 192,
+ "spearman_r": -0.3587221254393612
+ },
+ {
+ "threshold": "bottom_75pct_CV",
+ "n_genes": 158,
+ "spearman_r": -0.39997839837699434
+ },
+ {
+ "threshold": "bottom_50pct_CV",
+ "n_genes": 106,
+ "spearman_r": -0.31398500635210375
+ },
+ {
+ "threshold": "bottom_25pct_CV",
+ "n_genes": 53,
+ "spearman_r": -0.08974539885307645
+ }
+ ]
+ },
+ "cell_resolution": {
+ "per_celltype_cv": [
+ {
+ "cell_type": "Astrocytes",
+ "n_cells": 120,
+ "median_cv_analytical": 1.037865400314331,
+ "median_cv_deepptr": 0.04969271644949913,
+ "mean_cv_analytical": 2.065990686416626,
+ "mean_cv_deepptr": 0.042765166610479355
+ },
+ {
+ "cell_type": "Cajal Retzius",
+ "n_cells": 34,
+ "median_cv_analytical": 0.9581262469291687,
+ "median_cv_deepptr": 0.035210926085710526,
+ "mean_cv_analytical": 1.2425631284713745,
+ "mean_cv_deepptr": 0.03074895218014717
+ },
+ {
+ "cell_type": "Cck-Tox",
+ "n_cells": 27,
+ "median_cv_analytical": 0.5500394701957703,
+ "median_cv_deepptr": 0.03183512017130852,
+ "mean_cv_analytical": 0.7018951177597046,
+ "mean_cv_deepptr": 0.02709321305155754
+ },
+ {
+ "cell_type": "Endothelial",
+ "n_cells": 87,
+ "median_cv_analytical": 1.258206844329834,
+ "median_cv_deepptr": 0.07260799407958984,
+ "mean_cv_analytical": 1.3927289247512817,
+ "mean_cv_deepptr": 0.06094517558813095
+ },
+ {
+ "cell_type": "GABA",
+ "n_cells": 61,
+ "median_cv_analytical": 0.6232943534851074,
+ "median_cv_deepptr": 0.03612678125500679,
+ "mean_cv_analytical": 0.7454152703285217,
+ "mean_cv_deepptr": 0.031618811190128326
+ },
+ {
+ "cell_type": "Granule immature",
+ "n_cells": 785,
+ "median_cv_analytical": 0.6696305274963379,
+ "median_cv_deepptr": 0.030969148501753807,
+ "mean_cv_analytical": 0.7786616086959839,
+ "mean_cv_deepptr": 0.026258107274770737
+ },
+ {
+ "cell_type": "Granule mature",
+ "n_cells": 1070,
+ "median_cv_analytical": 0.7358936667442322,
+ "median_cv_deepptr": 0.029770459979772568,
+ "mean_cv_analytical": 0.8565810322761536,
+ "mean_cv_deepptr": 0.025847110897302628
+ },
+ {
+ "cell_type": "Microglia",
+ "n_cells": 81,
+ "median_cv_analytical": 2.034620523452759,
+ "median_cv_deepptr": 0.05030623823404312,
+ "mean_cv_analytical": 2.5370047092437744,
+ "mean_cv_deepptr": 0.04304993152618408
+ },
+ {
+ "cell_type": "Mossy",
+ "n_cells": 75,
+ "median_cv_analytical": 0.5362868309020996,
+ "median_cv_deepptr": 0.033555418252944946,
+ "mean_cv_analytical": 0.6848810315132141,
+ "mean_cv_deepptr": 0.02926183119416237
+ },
+ {
+ "cell_type": "Neuroblast",
+ "n_cells": 417,
+ "median_cv_analytical": 0.8587535619735718,
+ "median_cv_deepptr": 0.04170010983943939,
+ "mean_cv_analytical": 1.133716106414795,
+ "mean_cv_deepptr": 0.035205960273742676
+ },
+ {
+ "cell_type": "OL",
+ "n_cells": 50,
+ "median_cv_analytical": 1.3443996906280518,
+ "median_cv_deepptr": 0.06878548860549927,
+ "mean_cv_analytical": 1.9315539598464966,
+ "mean_cv_deepptr": 0.060547325760126114
+ },
+ {
+ "cell_type": "OPC",
+ "n_cells": 53,
+ "median_cv_analytical": 0.815068244934082,
+ "median_cv_deepptr": 0.0567430779337883,
+ "mean_cv_analytical": 1.5061569213867188,
+ "mean_cv_deepptr": 0.049455419182777405
+ },
+ {
+ "cell_type": "Radial Glia-like",
+ "n_cells": 51,
+ "median_cv_analytical": 0.8714540004730225,
+ "median_cv_deepptr": 0.05179445818066597,
+ "mean_cv_analytical": 1.744782567024231,
+ "mean_cv_deepptr": 0.04362059757113457
+ },
+ {
+ "cell_type": "nIPC",
+ "n_cells": 19,
+ "median_cv_analytical": 0.8511570692062378,
+ "median_cv_deepptr": 0.04830135032534599,
+ "mean_cv_analytical": 1.1737077236175537,
+ "mean_cv_deepptr": 0.04091320559382439
+ }
+ ],
+ "anova_n_tested": 300,
+ "anova_n_sig_analytical": 300,
+ "anova_n_sig_deepptr": 300,
+ "anova_median_F_analytical": 54.830108642578125,
+ "anova_median_F_deepptr": 537.62548828125
+ },
+ "disentanglement": {
+ "n_pt_specific_genes": 11,
+ "pt_specific_genes": [
+ "Eml6",
+ "Cnot6",
+ "Scfd1",
+ "Nrxn3",
+ "Kcnma1",
+ "Cacnb2",
+ "Taf13",
+ "Rmdn1",
+ "Palm2",
+ "Cdh8",
+ "Tmem108"
+ ],
+ "n_t_specific_genes": 0,
+ "t_specific_genes": [],
+ "pt_vs_expr_ari": 0.2671286775862764,
+ "pt_vs_expr_nmi": 0.3704443764759361,
+ "n_pt_de_genes": 300,
+ "top_pt_de_genes": [
+ {
+ "gene": "Tnr",
+ "H_statistic": 1533.366266091544,
+ "p_value": 0.0,
+ "fold_change": 1.1819950342178345
+ },
+ {
+ "gene": "Vmp1",
+ "H_statistic": 1451.2478969852395,
+ "p_value": 0.0,
+ "fold_change": 1.2288334369659424
+ },
+ {
+ "gene": "Dapk1",
+ "H_statistic": 1546.6111450613307,
+ "p_value": 0.0,
+ "fold_change": 1.1675533056259155
+ },
+ {
+ "gene": "Kcnma1",
+ "H_statistic": 1519.3468882649072,
+ "p_value": 0.0,
+ "fold_change": 1.11080801486969
+ },
+ {
+ "gene": "Cacnb2",
+ "H_statistic": 1515.7900037483437,
+ "p_value": 0.0,
+ "fold_change": 1.1004377603530884
+ },
+ {
+ "gene": "Rmdn1",
+ "H_statistic": 1616.2543511793092,
+ "p_value": 0.0,
+ "fold_change": 1.1346839666366577
+ },
+ {
+ "gene": "Samd12",
+ "H_statistic": 1433.6199306560575,
+ "p_value": 3.54321061287721e-309,
+ "fold_change": 1.146824598312378
+ },
+ {
+ "gene": "Eif3k",
+ "H_statistic": 1406.0461625188418,
+ "p_value": 3.377085499536065e-303,
+ "fold_change": 1.7036584615707397
+ },
+ {
+ "gene": "Myl6",
+ "H_statistic": 1405.2783274363155,
+ "p_value": 4.9549403643472094e-303,
+ "fold_change": 2.6013126373291016
+ },
+ {
+ "gene": "2010300C02Rik",
+ "H_statistic": 1397.0629359204936,
+ "p_value": 2.9953341972979423e-301,
+ "fold_change": 1.7101900577545166
+ },
+ {
+ "gene": "Rpl37a",
+ "H_statistic": 1306.7601736776787,
+ "p_value": 1.1388427869365306e-281,
+ "fold_change": 1.8508563041687012
+ },
+ {
+ "gene": "Cdh8",
+ "H_statistic": 1300.5562976457068,
+ "p_value": 2.5208950836280437e-280,
+ "fold_change": 1.1398566961288452
+ },
+ {
+ "gene": "Ptk2",
+ "H_statistic": 1289.8494393795609,
+ "p_value": 5.283660460584932e-278,
+ "fold_change": 3.05499529838562
+ },
+ {
+ "gene": "Erdr1",
+ "H_statistic": 1272.9761164998563,
+ "p_value": 2.4055841770936896e-274,
+ "fold_change": 2.2879762649536133
+ },
+ {
+ "gene": "Rfx3",
+ "H_statistic": 1266.5863773970893,
+ "p_value": 5.8418818476206325e-273,
+ "fold_change": 1.7074975967407227
+ },
+ {
+ "gene": "Sfswap",
+ "H_statistic": 1262.8777599728467,
+ "p_value": 3.7204658593671595e-272,
+ "fold_change": 2.057882785797119
+ },
+ {
+ "gene": "Ppp3ca",
+ "H_statistic": 1262.0503935996123,
+ "p_value": 5.623069877289324e-272,
+ "fold_change": 1.7260609865188599
+ },
+ {
+ "gene": "Stxbp6",
+ "H_statistic": 1261.113772301682,
+ "p_value": 8.975037945460618e-272,
+ "fold_change": 1.390549898147583
+ },
+ {
+ "gene": "Rpl37",
+ "H_statistic": 1257.7427888641757,
+ "p_value": 4.829202943626965e-271,
+ "fold_change": 1.7165744304656982
+ },
+ {
+ "gene": "Scfd1",
+ "H_statistic": 1240.925403805081,
+ "p_value": 2.137407878218827e-267,
+ "fold_change": 1.0781753063201904
+ }
+ ]
+ },
+ "statistical_testing": {
+ "ct_a": "Granule mature",
+ "ct_b": "Granule immature",
+ "n_cells_a": 1070,
+ "n_cells_b": 785,
+ "n_sig_posterior": 0,
+ "n_sig_ttest": 142,
+ "n_both": 0,
+ "n_posterior_only": 0,
+ "n_ttest_only": 142
+ }
+ }
+}
\ No newline at end of file
diff --git a/output/deep_advantages/results/dentate_gyrus_advantages.json b/output/deep_advantages/results/dentate_gyrus_advantages.json
new file mode 100644
index 0000000000000000000000000000000000000000..3db5cc5198b27cc2db510cefaf60b6410e5e52ba
--- /dev/null
+++ b/output/deep_advantages/results/dentate_gyrus_advantages.json
@@ -0,0 +1,373 @@
+{
+ "uncertainty_filtering": {
+ "mouse": [
+ {
+ "threshold": "all",
+ "n_genes": 216,
+ "spearman_r": -0.28539711439597953
+ },
+ {
+ "threshold": "CV<1.0",
+ "n_genes": 216,
+ "spearman_r": -0.28539711439597953
+ },
+ {
+ "threshold": "CV<0.75",
+ "n_genes": 216,
+ "spearman_r": -0.28539711439597953
+ },
+ {
+ "threshold": "CV<0.5",
+ "n_genes": 216,
+ "spearman_r": -0.28539711439597953
+ },
+ {
+ "threshold": "CV<0.3",
+ "n_genes": 215,
+ "spearman_r": -0.2859663877215545
+ },
+ {
+ "threshold": "CV<0.2",
+ "n_genes": 194,
+ "spearman_r": -0.2808110516824419
+ },
+ {
+ "threshold": "bottom_75pct_CV",
+ "n_genes": 162,
+ "spearman_r": -0.27764299756831096
+ },
+ {
+ "threshold": "bottom_50pct_CV",
+ "n_genes": 108,
+ "spearman_r": -0.1943849019215563
+ },
+ {
+ "threshold": "bottom_25pct_CV",
+ "n_genes": 54,
+ "spearman_r": -0.18749761768629689
+ }
+ ],
+ "human": [
+ {
+ "threshold": "all",
+ "n_genes": 211,
+ "spearman_r": -0.3582097560135093
+ },
+ {
+ "threshold": "CV<1.0",
+ "n_genes": 211,
+ "spearman_r": -0.3582097560135093
+ },
+ {
+ "threshold": "CV<0.75",
+ "n_genes": 211,
+ "spearman_r": -0.3582097560135093
+ },
+ {
+ "threshold": "CV<0.5",
+ "n_genes": 211,
+ "spearman_r": -0.3582097560135093
+ },
+ {
+ "threshold": "CV<0.3",
+ "n_genes": 210,
+ "spearman_r": -0.3577103191264039
+ },
+ {
+ "threshold": "CV<0.2",
+ "n_genes": 192,
+ "spearman_r": -0.3587221254393612
+ },
+ {
+ "threshold": "bottom_75pct_CV",
+ "n_genes": 158,
+ "spearman_r": -0.39997839837699434
+ },
+ {
+ "threshold": "bottom_50pct_CV",
+ "n_genes": 106,
+ "spearman_r": -0.31398500635210375
+ },
+ {
+ "threshold": "bottom_25pct_CV",
+ "n_genes": 53,
+ "spearman_r": -0.08974539885307645
+ }
+ ]
+ },
+ "cell_resolution": {
+ "per_celltype_cv": [
+ {
+ "cell_type": "Astrocytes",
+ "n_cells": 120,
+ "median_cv_analytical": 1.037865400314331,
+ "median_cv_deepptr": 0.04969271644949913,
+ "mean_cv_analytical": 2.065990686416626,
+ "mean_cv_deepptr": 0.042765166610479355
+ },
+ {
+ "cell_type": "Cajal Retzius",
+ "n_cells": 34,
+ "median_cv_analytical": 0.9581262469291687,
+ "median_cv_deepptr": 0.035210926085710526,
+ "mean_cv_analytical": 1.2425631284713745,
+ "mean_cv_deepptr": 0.03074895218014717
+ },
+ {
+ "cell_type": "Cck-Tox",
+ "n_cells": 27,
+ "median_cv_analytical": 0.5500394701957703,
+ "median_cv_deepptr": 0.03183512017130852,
+ "mean_cv_analytical": 0.7018951177597046,
+ "mean_cv_deepptr": 0.02709321305155754
+ },
+ {
+ "cell_type": "Endothelial",
+ "n_cells": 87,
+ "median_cv_analytical": 1.258206844329834,
+ "median_cv_deepptr": 0.07260799407958984,
+ "mean_cv_analytical": 1.3927289247512817,
+ "mean_cv_deepptr": 0.06094517558813095
+ },
+ {
+ "cell_type": "GABA",
+ "n_cells": 61,
+ "median_cv_analytical": 0.6232943534851074,
+ "median_cv_deepptr": 0.03612678125500679,
+ "mean_cv_analytical": 0.7454152703285217,
+ "mean_cv_deepptr": 0.031618811190128326
+ },
+ {
+ "cell_type": "Granule immature",
+ "n_cells": 785,
+ "median_cv_analytical": 0.6696305274963379,
+ "median_cv_deepptr": 0.030969148501753807,
+ "mean_cv_analytical": 0.7786616086959839,
+ "mean_cv_deepptr": 0.026258107274770737
+ },
+ {
+ "cell_type": "Granule mature",
+ "n_cells": 1070,
+ "median_cv_analytical": 0.7358936667442322,
+ "median_cv_deepptr": 0.029770459979772568,
+ "mean_cv_analytical": 0.8565810322761536,
+ "mean_cv_deepptr": 0.025847110897302628
+ },
+ {
+ "cell_type": "Microglia",
+ "n_cells": 81,
+ "median_cv_analytical": 2.034620523452759,
+ "median_cv_deepptr": 0.05030623823404312,
+ "mean_cv_analytical": 2.5370047092437744,
+ "mean_cv_deepptr": 0.04304993152618408
+ },
+ {
+ "cell_type": "Mossy",
+ "n_cells": 75,
+ "median_cv_analytical": 0.5362868309020996,
+ "median_cv_deepptr": 0.033555418252944946,
+ "mean_cv_analytical": 0.6848810315132141,
+ "mean_cv_deepptr": 0.02926183119416237
+ },
+ {
+ "cell_type": "Neuroblast",
+ "n_cells": 417,
+ "median_cv_analytical": 0.8587535619735718,
+ "median_cv_deepptr": 0.04170010983943939,
+ "mean_cv_analytical": 1.133716106414795,
+ "mean_cv_deepptr": 0.035205960273742676
+ },
+ {
+ "cell_type": "OL",
+ "n_cells": 50,
+ "median_cv_analytical": 1.3443996906280518,
+ "median_cv_deepptr": 0.06878548860549927,
+ "mean_cv_analytical": 1.9315539598464966,
+ "mean_cv_deepptr": 0.060547325760126114
+ },
+ {
+ "cell_type": "OPC",
+ "n_cells": 53,
+ "median_cv_analytical": 0.815068244934082,
+ "median_cv_deepptr": 0.0567430779337883,
+ "mean_cv_analytical": 1.5061569213867188,
+ "mean_cv_deepptr": 0.049455419182777405
+ },
+ {
+ "cell_type": "Radial Glia-like",
+ "n_cells": 51,
+ "median_cv_analytical": 0.8714540004730225,
+ "median_cv_deepptr": 0.05179445818066597,
+ "mean_cv_analytical": 1.744782567024231,
+ "mean_cv_deepptr": 0.04362059757113457
+ },
+ {
+ "cell_type": "nIPC",
+ "n_cells": 19,
+ "median_cv_analytical": 0.8511570692062378,
+ "median_cv_deepptr": 0.04830135032534599,
+ "mean_cv_analytical": 1.1737077236175537,
+ "mean_cv_deepptr": 0.04091320559382439
+ }
+ ],
+ "anova_n_tested": 300,
+ "anova_n_sig_analytical": 300,
+ "anova_n_sig_deepptr": 300,
+ "anova_median_F_analytical": 54.830108642578125,
+ "anova_median_F_deepptr": 537.62548828125
+ },
+ "disentanglement": {
+ "n_pt_specific_genes": 11,
+ "pt_specific_genes": [
+ "Eml6",
+ "Cnot6",
+ "Scfd1",
+ "Nrxn3",
+ "Kcnma1",
+ "Cacnb2",
+ "Taf13",
+ "Rmdn1",
+ "Palm2",
+ "Cdh8",
+ "Tmem108"
+ ],
+ "n_t_specific_genes": 0,
+ "t_specific_genes": [],
+ "pt_vs_expr_ari": 0.2671286775862764,
+ "pt_vs_expr_nmi": 0.3704443764759361,
+ "n_pt_de_genes": 300,
+ "top_pt_de_genes": [
+ {
+ "gene": "Tnr",
+ "H_statistic": 1533.366266091544,
+ "p_value": 0.0,
+ "fold_change": 1.1819950342178345
+ },
+ {
+ "gene": "Vmp1",
+ "H_statistic": 1451.2478969852395,
+ "p_value": 0.0,
+ "fold_change": 1.2288334369659424
+ },
+ {
+ "gene": "Dapk1",
+ "H_statistic": 1546.6111450613307,
+ "p_value": 0.0,
+ "fold_change": 1.1675533056259155
+ },
+ {
+ "gene": "Kcnma1",
+ "H_statistic": 1519.3468882649072,
+ "p_value": 0.0,
+ "fold_change": 1.11080801486969
+ },
+ {
+ "gene": "Cacnb2",
+ "H_statistic": 1515.7900037483437,
+ "p_value": 0.0,
+ "fold_change": 1.1004377603530884
+ },
+ {
+ "gene": "Rmdn1",
+ "H_statistic": 1616.2543511793092,
+ "p_value": 0.0,
+ "fold_change": 1.1346839666366577
+ },
+ {
+ "gene": "Samd12",
+ "H_statistic": 1433.6199306560575,
+ "p_value": 3.54321061287721e-309,
+ "fold_change": 1.146824598312378
+ },
+ {
+ "gene": "Eif3k",
+ "H_statistic": 1406.0461625188418,
+ "p_value": 3.377085499536065e-303,
+ "fold_change": 1.7036584615707397
+ },
+ {
+ "gene": "Myl6",
+ "H_statistic": 1405.2783274363155,
+ "p_value": 4.9549403643472094e-303,
+ "fold_change": 2.6013126373291016
+ },
+ {
+ "gene": "2010300C02Rik",
+ "H_statistic": 1397.0629359204936,
+ "p_value": 2.9953341972979423e-301,
+ "fold_change": 1.7101900577545166
+ },
+ {
+ "gene": "Rpl37a",
+ "H_statistic": 1306.7601736776787,
+ "p_value": 1.1388427869365306e-281,
+ "fold_change": 1.8508563041687012
+ },
+ {
+ "gene": "Cdh8",
+ "H_statistic": 1300.5562976457068,
+ "p_value": 2.5208950836280437e-280,
+ "fold_change": 1.1398566961288452
+ },
+ {
+ "gene": "Ptk2",
+ "H_statistic": 1289.8494393795609,
+ "p_value": 5.283660460584932e-278,
+ "fold_change": 3.05499529838562
+ },
+ {
+ "gene": "Erdr1",
+ "H_statistic": 1272.9761164998563,
+ "p_value": 2.4055841770936896e-274,
+ "fold_change": 2.2879762649536133
+ },
+ {
+ "gene": "Rfx3",
+ "H_statistic": 1266.5863773970893,
+ "p_value": 5.8418818476206325e-273,
+ "fold_change": 1.7074975967407227
+ },
+ {
+ "gene": "Sfswap",
+ "H_statistic": 1262.8777599728467,
+ "p_value": 3.7204658593671595e-272,
+ "fold_change": 2.057882785797119
+ },
+ {
+ "gene": "Ppp3ca",
+ "H_statistic": 1262.0503935996123,
+ "p_value": 5.623069877289324e-272,
+ "fold_change": 1.7260609865188599
+ },
+ {
+ "gene": "Stxbp6",
+ "H_statistic": 1261.113772301682,
+ "p_value": 8.975037945460618e-272,
+ "fold_change": 1.390549898147583
+ },
+ {
+ "gene": "Rpl37",
+ "H_statistic": 1257.7427888641757,
+ "p_value": 4.829202943626965e-271,
+ "fold_change": 1.7165744304656982
+ },
+ {
+ "gene": "Scfd1",
+ "H_statistic": 1240.925403805081,
+ "p_value": 2.137407878218827e-267,
+ "fold_change": 1.0781753063201904
+ }
+ ]
+ },
+ "statistical_testing": {
+ "ct_a": "Granule mature",
+ "ct_b": "Granule immature",
+ "n_cells_a": 1070,
+ "n_cells_b": 785,
+ "n_sig_posterior": 0,
+ "n_sig_ttest": 142,
+ "n_both": 0,
+ "n_posterior_only": 0,
+ "n_ttest_only": 142
+ }
+}
\ No newline at end of file
diff --git a/output/deep_advantages/results/pancreas_advantages.json b/output/deep_advantages/results/pancreas_advantages.json
new file mode 100644
index 0000000000000000000000000000000000000000..336c77a2fb9b3795068ce93852b6ee830efc6713
--- /dev/null
+++ b/output/deep_advantages/results/pancreas_advantages.json
@@ -0,0 +1,365 @@
+{
+ "uncertainty_filtering": {
+ "mouse": [
+ {
+ "threshold": "all",
+ "n_genes": 251,
+ "spearman_r": -0.1976794527336332
+ },
+ {
+ "threshold": "CV<1.0",
+ "n_genes": 251,
+ "spearman_r": -0.1976794527336332
+ },
+ {
+ "threshold": "CV<0.75",
+ "n_genes": 251,
+ "spearman_r": -0.1976794527336332
+ },
+ {
+ "threshold": "CV<0.5",
+ "n_genes": 250,
+ "spearman_r": -0.20403060683747745
+ },
+ {
+ "threshold": "CV<0.3",
+ "n_genes": 250,
+ "spearman_r": -0.20403060683747745
+ },
+ {
+ "threshold": "CV<0.2",
+ "n_genes": 249,
+ "spearman_r": -0.20048744674989727
+ },
+ {
+ "threshold": "bottom_75pct_CV",
+ "n_genes": 188,
+ "spearman_r": -0.2188323427372238
+ },
+ {
+ "threshold": "bottom_50pct_CV",
+ "n_genes": 126,
+ "spearman_r": -0.23679940007499065
+ },
+ {
+ "threshold": "bottom_25pct_CV",
+ "n_genes": 63,
+ "spearman_r": -0.2579205069124424
+ }
+ ],
+ "human": [
+ {
+ "threshold": "all",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<1.0",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<0.75",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<0.5",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<0.3",
+ "n_genes": 236,
+ "spearman_r": -0.27676078712075614
+ },
+ {
+ "threshold": "CV<0.2",
+ "n_genes": 235,
+ "spearman_r": -0.27315207370726874
+ },
+ {
+ "threshold": "bottom_75pct_CV",
+ "n_genes": 177,
+ "spearman_r": -0.2899948602809608
+ },
+ {
+ "threshold": "bottom_50pct_CV",
+ "n_genes": 118,
+ "spearman_r": -0.2920772191767282
+ },
+ {
+ "threshold": "bottom_25pct_CV",
+ "n_genes": 59,
+ "spearman_r": -0.3545931413753938
+ }
+ ]
+ },
+ "cell_resolution": {
+ "per_celltype_cv": [
+ {
+ "cell_type": "Alpha",
+ "n_cells": 481,
+ "median_cv_analytical": 0.5714874267578125,
+ "median_cv_deepptr": 0.025115380063652992,
+ "mean_cv_analytical": 0.6858336329460144,
+ "mean_cv_deepptr": 0.02439717948436737
+ },
+ {
+ "cell_type": "Beta",
+ "n_cells": 591,
+ "median_cv_analytical": 0.5670088529586792,
+ "median_cv_deepptr": 0.1528678983449936,
+ "mean_cv_analytical": 0.6656529903411865,
+ "mean_cv_deepptr": 0.1491723507642746
+ },
+ {
+ "cell_type": "Delta",
+ "n_cells": 70,
+ "median_cv_analytical": 0.44335344433784485,
+ "median_cv_deepptr": 0.02082059532403946,
+ "mean_cv_analytical": 0.7205255031585693,
+ "mean_cv_deepptr": 0.01994817890226841
+ },
+ {
+ "cell_type": "Ductal",
+ "n_cells": 916,
+ "median_cv_analytical": 0.6001600027084351,
+ "median_cv_deepptr": 0.02392425574362278,
+ "mean_cv_analytical": 1.5890529155731201,
+ "mean_cv_deepptr": 0.022229716181755066
+ },
+ {
+ "cell_type": "Epsilon",
+ "n_cells": 142,
+ "median_cv_analytical": 0.5356361865997314,
+ "median_cv_deepptr": 0.02128124237060547,
+ "mean_cv_analytical": 0.7422852516174316,
+ "mean_cv_deepptr": 0.02046981453895569
+ },
+ {
+ "cell_type": "Ngn3 high EP",
+ "n_cells": 642,
+ "median_cv_analytical": 0.6426572799682617,
+ "median_cv_deepptr": 0.023328058421611786,
+ "mean_cv_analytical": 0.9787807464599609,
+ "mean_cv_deepptr": 0.021852802485227585
+ },
+ {
+ "cell_type": "Ngn3 low EP",
+ "n_cells": 262,
+ "median_cv_analytical": 0.5913139581680298,
+ "median_cv_deepptr": 0.025578055530786514,
+ "mean_cv_analytical": 1.2815543413162231,
+ "mean_cv_deepptr": 0.023869693279266357
+ },
+ {
+ "cell_type": "Pre-endocrine",
+ "n_cells": 592,
+ "median_cv_analytical": 0.6505065560340881,
+ "median_cv_deepptr": 0.019794151186943054,
+ "mean_cv_analytical": 0.8129222393035889,
+ "mean_cv_deepptr": 0.018655382096767426
+ }
+ ],
+ "anova_n_tested": 300,
+ "anova_n_sig_analytical": 299,
+ "anova_n_sig_deepptr": 300,
+ "anova_median_F_analytical": NaN,
+ "anova_median_F_deepptr": 244.958740234375
+ },
+ "disentanglement": {
+ "n_pt_specific_genes": 44,
+ "pt_specific_genes": [
+ "Adgrb3",
+ "Pard3b",
+ "Tmtc2",
+ "Rfx6",
+ "Trim17",
+ "Ptprn2",
+ "Dip2c",
+ "Fhit",
+ "Ube2e2",
+ "Kcnma1",
+ "Farp1",
+ "Rims2",
+ "Igf2bp2",
+ "Stxbp5l",
+ "Phldb2",
+ "Fbxl17",
+ "Park2",
+ "Dnajc1",
+ "Pbx3",
+ "Nr6a1",
+ "Kcnh7",
+ "9030622O22Rik",
+ "Zmynd8",
+ "Mbd5",
+ "Macrod2",
+ "Hnf1aos1",
+ "Sdk1",
+ "Pan3",
+ "Chchd3",
+ "Tmcc1",
+ "Cacna1c",
+ "Snd1",
+ "Ccser1",
+ "Ttll3",
+ "Tmc4",
+ "Egln2",
+ "Gm21974",
+ "Ins2",
+ "Kcnq1",
+ "Fam155a",
+ "Wwox",
+ "Tcf12",
+ "Rora",
+ "Mid1"
+ ],
+ "n_t_specific_genes": 6,
+ "t_specific_genes": [
+ "Sphkap",
+ "2010111I01Rik",
+ "Myh9",
+ "Nol4",
+ "Itpr1",
+ "Abcc8"
+ ],
+ "pt_vs_expr_ari": 0.077128756533571,
+ "pt_vs_expr_nmi": 0.18141567420189855,
+ "n_pt_de_genes": 300,
+ "top_pt_de_genes": [
+ {
+ "gene": "Tmtc2",
+ "H_statistic": 1507.252819412225,
+ "p_value": 0.0,
+ "fold_change": 1.1294591426849365
+ },
+ {
+ "gene": "Ptprn2",
+ "H_statistic": 1453.3068265183394,
+ "p_value": 0.0,
+ "fold_change": 1.3904372453689575
+ },
+ {
+ "gene": "Fhit",
+ "H_statistic": 1457.3716975334148,
+ "p_value": 0.0,
+ "fold_change": 1.5617649555206299
+ },
+ {
+ "gene": "Park2",
+ "H_statistic": 1606.4708053162663,
+ "p_value": 0.0,
+ "fold_change": 1.0910781621932983
+ },
+ {
+ "gene": "Macrod2",
+ "H_statistic": 1498.6858013593953,
+ "p_value": 0.0,
+ "fold_change": 1.4149595499038696
+ },
+ {
+ "gene": "Chchd3",
+ "H_statistic": 1502.83262766733,
+ "p_value": 0.0,
+ "fold_change": 1.3431732654571533
+ },
+ {
+ "gene": "Snd1",
+ "H_statistic": 1510.9010872869696,
+ "p_value": 0.0,
+ "fold_change": 1.5494927167892456
+ },
+ {
+ "gene": "Ins2",
+ "H_statistic": 1623.6118081391649,
+ "p_value": 0.0,
+ "fold_change": 26.470022201538086
+ },
+ {
+ "gene": "Rora",
+ "H_statistic": 1491.8154065673139,
+ "p_value": 0.0,
+ "fold_change": 2.022663116455078
+ },
+ {
+ "gene": "9030622O22Rik",
+ "H_statistic": 1407.8904321594011,
+ "p_value": 5.714914382762847e-305,
+ "fold_change": 1.4340518712997437
+ },
+ {
+ "gene": "Fbxl17",
+ "H_statistic": 1401.9243404754493,
+ "p_value": 1.1261837231059974e-303,
+ "fold_change": 1.3535175323486328
+ },
+ {
+ "gene": "Ccser1",
+ "H_statistic": 1380.9660261606807,
+ "p_value": 3.975422350686473e-299,
+ "fold_change": 1.1388120651245117
+ },
+ {
+ "gene": "Kcnh7",
+ "H_statistic": 1372.331765284582,
+ "p_value": 2.9711818753969144e-297,
+ "fold_change": 1.4253920316696167
+ },
+ {
+ "gene": "Egln2",
+ "H_statistic": 1370.996708502923,
+ "p_value": 5.789247134264385e-297,
+ "fold_change": 1.140360713005066
+ },
+ {
+ "gene": "Stxbp5l",
+ "H_statistic": 1352.9608944222837,
+ "p_value": 4.744363813172019e-293,
+ "fold_change": 1.7202287912368774
+ },
+ {
+ "gene": "Sdk1",
+ "H_statistic": 1308.955208207672,
+ "p_value": 1.6777292275912853e-283,
+ "fold_change": 1.119990348815918
+ },
+ {
+ "gene": "Rims2",
+ "H_statistic": 1308.903145513165,
+ "p_value": 1.7219419918267907e-283,
+ "fold_change": 1.3955633640289307
+ },
+ {
+ "gene": "Rfx6",
+ "H_statistic": 1302.83531755728,
+ "p_value": 3.56962967882861e-282,
+ "fold_change": 1.488563895225525
+ },
+ {
+ "gene": "Wwox",
+ "H_statistic": 1302.6454148099776,
+ "p_value": 3.924898371957578e-282,
+ "fold_change": 1.4599933624267578
+ },
+ {
+ "gene": "Gm21974",
+ "H_statistic": 1289.113859857544,
+ "p_value": 3.3876946827012372e-279,
+ "fold_change": 1.0790175199508667
+ }
+ ]
+ },
+ "statistical_testing": {
+ "ct_a": "Ductal",
+ "ct_b": "Ngn3 high EP",
+ "n_cells_a": 916,
+ "n_cells_b": 642,
+ "n_sig_posterior": 0,
+ "n_sig_ttest": 288,
+ "n_both": 0,
+ "n_posterior_only": 0,
+ "n_ttest_only": 288
+ }
+}
\ No newline at end of file
diff --git a/output/deep_benchmark/figures/dentate_gyrus_analytical_vs_deepptr.png b/output/deep_benchmark/figures/dentate_gyrus_analytical_vs_deepptr.png
new file mode 100644
index 0000000000000000000000000000000000000000..65ca9c3df3403efa7de4936767975cae82d407b4
Binary files /dev/null and b/output/deep_benchmark/figures/dentate_gyrus_analytical_vs_deepptr.png differ
diff --git a/output/deep_benchmark/figures/dentate_gyrus_training_curves.png b/output/deep_benchmark/figures/dentate_gyrus_training_curves.png
new file mode 100644
index 0000000000000000000000000000000000000000..ee3c4dd008d13d9bda0a00a2ded1b1ffbbd0d820
Binary files /dev/null and b/output/deep_benchmark/figures/dentate_gyrus_training_curves.png differ
diff --git a/output/deep_benchmark/figures/dentate_gyrus_uncertainty.png b/output/deep_benchmark/figures/dentate_gyrus_uncertainty.png
new file mode 100644
index 0000000000000000000000000000000000000000..0678651429211bf2ac28c82864d8b66b36ae2b43
Binary files /dev/null and b/output/deep_benchmark/figures/dentate_gyrus_uncertainty.png differ
diff --git a/output/deep_benchmark/figures/pancreas_analytical_vs_deepptr.png b/output/deep_benchmark/figures/pancreas_analytical_vs_deepptr.png
new file mode 100644
index 0000000000000000000000000000000000000000..685dcbe3d997821ebf8bdfb6c716f4b1546fe177
Binary files /dev/null and b/output/deep_benchmark/figures/pancreas_analytical_vs_deepptr.png differ
diff --git a/output/deep_benchmark/figures/synthetic_training_curves.png b/output/deep_benchmark/figures/synthetic_training_curves.png
new file mode 100644
index 0000000000000000000000000000000000000000..ab943cb5137707425ee8095286130c7b37323487
Binary files /dev/null and b/output/deep_benchmark/figures/synthetic_training_curves.png differ
diff --git a/output/deep_benchmark/results/combined_benchmark.json b/output/deep_benchmark/results/combined_benchmark.json
new file mode 100644
index 0000000000000000000000000000000000000000..258949316d9854720ce22c431f200174b7c1691d
--- /dev/null
+++ b/output/deep_benchmark/results/combined_benchmark.json
@@ -0,0 +1,249 @@
+{
+ "synthetic": {
+ "gamma_recovery_per_gene": 0.8552942267330017,
+ "gamma_recovery_global": 0.853245950458172,
+ "ci_coverage_95": 0.26692,
+ "latent_recovery_T": 0.5561008036714264,
+ "latent_recovery_PT": 0.5348961912017587,
+ "n_epochs": 150,
+ "final_train_loss": 873.7797139485677,
+ "final_val_loss": 878.2410888671875,
+ "training_time_s": 24.290624618530273
+ },
+ "pancreas": {
+ "dataset": "pancreas",
+ "n_cells": 3696,
+ "n_genes": 11906,
+ "deepptr_epochs": 100,
+ "deepptr_time_s": 691.1493718624115,
+ "deepptr_final_val_loss": 581.9227905273438,
+ "halflife": {
+ "mouse_herzog": {
+ "analytical": {
+ "spearman_r": -0.34966929477006137,
+ "pearson_r": -0.23291966884468007,
+ "n_genes": 4611
+ },
+ "deepptr": {
+ "spearman_r": -0.19762101977653473,
+ "pearson_r": -0.13793936916451716,
+ "n_genes": 251
+ }
+ },
+ "human_schofield": {
+ "analytical": {
+ "spearman_r": -0.4020872107350974,
+ "pearson_r": -0.2849205668358859,
+ "n_genes": 4308
+ },
+ "deepptr": {
+ "spearman_r": -0.2767452667406712,
+ "pearson_r": -0.24032216943506846,
+ "n_genes": 236
+ }
+ }
+ },
+ "enrichment": {
+ "ARE": {
+ "analytical": {
+ "U_statistic": 44637.0,
+ "p_value": 0.9841054448243868,
+ "n_genes_in_set": 14
+ },
+ "deepptr": {
+ "U_statistic": NaN,
+ "p_value": NaN,
+ "n_genes_in_set": 0
+ }
+ },
+ "NMD": {
+ "analytical": {
+ "U_statistic": 141636.0,
+ "p_value": 0.31160184709114613,
+ "n_genes_in_set": 29
+ },
+ "deepptr": {
+ "U_statistic": 361.0,
+ "p_value": 0.705555655316379,
+ "n_genes_in_set": 3
+ }
+ }
+ },
+ "gamma_agreement": {
+ "spearman_r": 0.9796487428351981,
+ "spearman_p": 2.4770516189667095e-190,
+ "pearson_r": 0.8430279503146496,
+ "pearson_p": 1.1020222468626118e-74,
+ "n_genes": 272
+ },
+ "robustness_analytical": [
+ {
+ "fraction": 0.5,
+ "repeat": 0,
+ "spearman_r": 0.9935493190803674,
+ "pearson_r": 0.9995819926261902,
+ "n_genes": 11906,
+ "n_cells_sampled": 1848
+ },
+ {
+ "fraction": 0.5,
+ "repeat": 1,
+ "spearman_r": 0.9957264356741521,
+ "pearson_r": 0.9995998740196228,
+ "n_genes": 11906,
+ "n_cells_sampled": 1848
+ },
+ {
+ "fraction": 0.8,
+ "repeat": 0,
+ "spearman_r": 0.9975692623733601,
+ "pearson_r": 0.9999009370803833,
+ "n_genes": 11906,
+ "n_cells_sampled": 2956
+ },
+ {
+ "fraction": 0.8,
+ "repeat": 1,
+ "spearman_r": 0.9972764513977047,
+ "pearson_r": 0.9998981952667236,
+ "n_genes": 11906,
+ "n_cells_sampled": 2956
+ }
+ ]
+ },
+ "dentate_gyrus": {
+ "dataset": "dentate_gyrus",
+ "n_cells": 2930,
+ "n_genes": 5325,
+ "deepptr_epochs": 100,
+ "deepptr_time_s": 922.1991696357727,
+ "deepptr_final_val_loss": 442.7923278808594,
+ "halflife": {
+ "mouse_herzog": {
+ "analytical": {
+ "spearman_r": -0.3179587682344816,
+ "pearson_r": -0.22408423951314294,
+ "n_genes": 1217
+ },
+ "deepptr": {
+ "spearman_r": -0.2852053996865196,
+ "pearson_r": -0.19832206076339523,
+ "n_genes": 216
+ }
+ },
+ "human_schofield": {
+ "analytical": {
+ "spearman_r": -0.3812073018847205,
+ "pearson_r": -0.2877806614932096,
+ "n_genes": 1126
+ },
+ "deepptr": {
+ "spearman_r": -0.35768791768630437,
+ "pearson_r": -0.2618435875729263,
+ "n_genes": 211
+ }
+ }
+ },
+ "enrichment": {
+ "ARE": {
+ "analytical": {
+ "U_statistic": 7270.0,
+ "p_value": 0.9358900987906894,
+ "n_genes_in_set": 5
+ },
+ "deepptr": {
+ "U_statistic": NaN,
+ "p_value": NaN,
+ "n_genes_in_set": 0
+ }
+ },
+ "NMD": {
+ "analytical": {
+ "U_statistic": 32198.0,
+ "p_value": 0.007296768008887519,
+ "n_genes_in_set": 11
+ },
+ "deepptr": {
+ "U_statistic": NaN,
+ "p_value": NaN,
+ "n_genes_in_set": 0
+ }
+ }
+ },
+ "gamma_agreement": {
+ "spearman_r": 0.9924993974774762,
+ "spearman_p": 5.8151180829002596e-254,
+ "pearson_r": 0.9121664644353008,
+ "pearson_p": 6.257196950215644e-109,
+ "n_genes": 278
+ },
+ "robustness_analytical": [
+ {
+ "fraction": 0.5,
+ "repeat": 0,
+ "spearman_r": 0.9901518220508172,
+ "pearson_r": 0.999853253364563,
+ "n_genes": 5325,
+ "n_cells_sampled": 1465
+ },
+ {
+ "fraction": 0.5,
+ "repeat": 1,
+ "spearman_r": 0.98792904515842,
+ "pearson_r": 0.9997460246086121,
+ "n_genes": 5325,
+ "n_cells_sampled": 1465
+ },
+ {
+ "fraction": 0.8,
+ "repeat": 0,
+ "spearman_r": 0.9944440945701716,
+ "pearson_r": 0.9999425411224365,
+ "n_genes": 5325,
+ "n_cells_sampled": 2344
+ },
+ {
+ "fraction": 0.8,
+ "repeat": 1,
+ "spearman_r": 0.9947911002635275,
+ "pearson_r": 0.9998971819877625,
+ "n_genes": 5325,
+ "n_cells_sampled": 2344
+ }
+ ]
+ },
+ "scifate": {
+ "dataset": "scifate",
+ "n_cells": 7404,
+ "n_genes_analytical": 7970,
+ "n_genes_deep": 500,
+ "ground_truth_corr": {
+ "analytical": {
+ "spearman_r": 0.9928182353002162,
+ "spearman_p": 0.0,
+ "n_genes": 7928
+ },
+ "deepptr": {
+ "spearman_r": 0.9977702950811802,
+ "spearman_p": 0.0,
+ "n_genes": 500
+ }
+ },
+ "halflife_human": {
+ "analytical": {
+ "spearman_r": -0.8122591276303375,
+ "n_genes": 6995
+ },
+ "deepptr": {
+ "spearman_r": -0.803948101301477,
+ "n_genes": 459
+ }
+ },
+ "gamma_agreement": {
+ "spearman_r": 0.9997681590726362,
+ "n_genes": 500
+ },
+ "deepptr_epochs": 100,
+ "deepptr_time_s": 1464.6209545135498
+ }
+}
\ No newline at end of file
diff --git a/output/deep_benchmark/results/dentate_gyrus_benchmark.json b/output/deep_benchmark/results/dentate_gyrus_benchmark.json
new file mode 100644
index 0000000000000000000000000000000000000000..a318fe6bf695dd08aa355d94bab58acc0e34a7e9
--- /dev/null
+++ b/output/deep_benchmark/results/dentate_gyrus_benchmark.json
@@ -0,0 +1,101 @@
+{
+ "dataset": "dentate_gyrus",
+ "n_cells": 2930,
+ "n_genes": 5325,
+ "deepptr_epochs": 100,
+ "deepptr_time_s": 922.1991696357727,
+ "deepptr_final_val_loss": 442.7923278808594,
+ "halflife": {
+ "mouse_herzog": {
+ "analytical": {
+ "spearman_r": -0.3179587682344816,
+ "pearson_r": -0.22408423951314294,
+ "n_genes": 1217
+ },
+ "deepptr": {
+ "spearman_r": -0.2852053996865196,
+ "pearson_r": -0.19832206076339523,
+ "n_genes": 216
+ }
+ },
+ "human_schofield": {
+ "analytical": {
+ "spearman_r": -0.3812073018847205,
+ "pearson_r": -0.2877806614932096,
+ "n_genes": 1126
+ },
+ "deepptr": {
+ "spearman_r": -0.35768791768630437,
+ "pearson_r": -0.2618435875729263,
+ "n_genes": 211
+ }
+ }
+ },
+ "enrichment": {
+ "ARE": {
+ "analytical": {
+ "U_statistic": 7270.0,
+ "p_value": 0.9358900987906894,
+ "n_genes_in_set": 5
+ },
+ "deepptr": {
+ "U_statistic": NaN,
+ "p_value": NaN,
+ "n_genes_in_set": 0
+ }
+ },
+ "NMD": {
+ "analytical": {
+ "U_statistic": 32198.0,
+ "p_value": 0.007296768008887519,
+ "n_genes_in_set": 11
+ },
+ "deepptr": {
+ "U_statistic": NaN,
+ "p_value": NaN,
+ "n_genes_in_set": 0
+ }
+ }
+ },
+ "gamma_agreement": {
+ "spearman_r": 0.9924993974774762,
+ "spearman_p": 5.8151180829002596e-254,
+ "pearson_r": 0.9121664644353008,
+ "pearson_p": 6.257196950215644e-109,
+ "n_genes": 278
+ },
+ "robustness_analytical": [
+ {
+ "fraction": 0.5,
+ "repeat": 0,
+ "spearman_r": 0.9901518220508172,
+ "pearson_r": 0.999853253364563,
+ "n_genes": 5325,
+ "n_cells_sampled": 1465
+ },
+ {
+ "fraction": 0.5,
+ "repeat": 1,
+ "spearman_r": 0.98792904515842,
+ "pearson_r": 0.9997460246086121,
+ "n_genes": 5325,
+ "n_cells_sampled": 1465
+ },
+ {
+ "fraction": 0.8,
+ "repeat": 0,
+ "spearman_r": 0.9944440945701716,
+ "pearson_r": 0.9999425411224365,
+ "n_genes": 5325,
+ "n_cells_sampled": 2344
+ },
+ {
+ "fraction": 0.8,
+ "repeat": 1,
+ "spearman_r": 0.9947911002635275,
+ "pearson_r": 0.9998971819877625,
+ "n_genes": 5325,
+ "n_cells_sampled": 2344
+ }
+ ]
+}
\ No newline at end of file
diff --git a/output/deep_benchmark/results/pancreas_benchmark.json b/output/deep_benchmark/results/pancreas_benchmark.json
new file mode 100644
index 0000000000000000000000000000000000000000..c36354dba914c41e0d14dd8383e7a66055cc429c
--- /dev/null
+++ b/output/deep_benchmark/results/pancreas_benchmark.json
@@ -0,0 +1,101 @@
+{
+ "dataset": "pancreas",
+ "n_cells": 3696,
+ "n_genes": 11906,
+ "deepptr_epochs": 100,
+ "deepptr_time_s": 691.1493718624115,
+ "deepptr_final_val_loss": 581.9227905273438,
+ "halflife": {
+ "mouse_herzog": {
+ "analytical": {
+ "spearman_r": -0.34966929477006137,
+ "pearson_r": -0.23291966884468007,
+ "n_genes": 4611
+ },
+ "deepptr": {
+ "spearman_r": -0.19762101977653473,
+ "pearson_r": -0.13793936916451716,
+ "n_genes": 251
+ }
+ },
+ "human_schofield": {
+ "analytical": {
+ "spearman_r": -0.4020872107350974,
+ "pearson_r": -0.2849205668358859,
+ "n_genes": 4308
+ },
+ "deepptr": {
+ "spearman_r": -0.2767452667406712,
+ "pearson_r": -0.24032216943506846,
+ "n_genes": 236
+ }
+ }
+ },
+ "enrichment": {
+ "ARE": {
+ "analytical": {
+ "U_statistic": 44637.0,
+ "p_value": 0.9841054448243868,
+ "n_genes_in_set": 14
+ },
+ "deepptr": {
+ "U_statistic": NaN,
+ "p_value": NaN,
+ "n_genes_in_set": 0
+ }
+ },
+ "NMD": {
+ "analytical": {
+ "U_statistic": 141636.0,
+ "p_value": 0.31160184709114613,
+ "n_genes_in_set": 29
+ },
+ "deepptr": {
+ "U_statistic": 361.0,
+ "p_value": 0.705555655316379,
+ "n_genes_in_set": 3
+ }
+ }
+ },
+ "gamma_agreement": {
+ "spearman_r": 0.9796487428351981,
+ "spearman_p": 2.4770516189667095e-190,
+ "pearson_r": 0.8430279503146496,
+ "pearson_p": 1.1020222468626118e-74,
+ "n_genes": 272
+ },
+ "robustness_analytical": [
+ {
+ "fraction": 0.5,
+ "repeat": 0,
+ "spearman_r": 0.9935493190803674,
+ "pearson_r": 0.9995819926261902,
+ "n_genes": 11906,
+ "n_cells_sampled": 1848
+ },
+ {
+ "fraction": 0.5,
+ "repeat": 1,
+ "spearman_r": 0.9957264356741521,
+ "pearson_r": 0.9995998740196228,
+ "n_genes": 11906,
+ "n_cells_sampled": 1848
+ },
+ {
+ "fraction": 0.8,
+ "repeat": 0,
+ "spearman_r": 0.9975692623733601,
+ "pearson_r": 0.9999009370803833,
+ "n_genes": 11906,
+ "n_cells_sampled": 2956
+ },
+ {
+ "fraction": 0.8,
+ "repeat": 1,
+ "spearman_r": 0.9972764513977047,
+ "pearson_r": 0.9998981952667236,
+ "n_genes": 11906,
+ "n_cells_sampled": 2956
+ }
+ ]
+}
\ No newline at end of file
diff --git a/output/deep_benchmark/results/scifate_benchmark.json b/output/deep_benchmark/results/scifate_benchmark.json
new file mode 100644
index 0000000000000000000000000000000000000000..05c90556fbc1973f34bd654b2be7a0ab85e4c62e
--- /dev/null
+++ b/output/deep_benchmark/results/scifate_benchmark.json
@@ -0,0 +1,34 @@
+{
+ "dataset": "scifate",
+ "n_cells": 7404,
+ "n_genes_analytical": 7970,
+ "n_genes_deep": 500,
+ "ground_truth_corr": {
+ "analytical": {
+ "spearman_r": 0.9928182353002162,
+ "spearman_p": 0.0,
+ "n_genes": 7928
+ },
+ "deepptr": {
+ "spearman_r": 0.9977702950811802,
+ "spearman_p": 0.0,
+ "n_genes": 500
+ }
+ },
+ "halflife_human": {
+ "analytical": {
+ "spearman_r": -0.8122591276303375,
+ "n_genes": 6995
+ },
+ "deepptr": {
+ "spearman_r": -0.803948101301477,
+ "n_genes": 459
+ }
+ },
+ "gamma_agreement": {
+ "spearman_r": 0.9997681590726362,
+ "n_genes": 500
+ },
+ "deepptr_epochs": 100,
+ "deepptr_time_s": 1464.6209545135498
+}
\ No newline at end of file
diff --git a/output/deep_benchmark/results/synthetic_recovery.json b/output/deep_benchmark/results/synthetic_recovery.json
new file mode 100644
index 0000000000000000000000000000000000000000..0742244f0c60e0d131b5cc8b1adcd989e1ae9d3e
--- /dev/null
+++ b/output/deep_benchmark/results/synthetic_recovery.json
@@ -0,0 +1,11 @@
+{
+ "gamma_recovery_per_gene": 0.8552942267330017,
+ "gamma_recovery_global": 0.853245950458172,
+ "ci_coverage_95": 0.26692,
+ "latent_recovery_T": 0.5561008036714264,
+ "latent_recovery_PT": 0.5348961912017587,
+ "n_epochs": 150,
+ "final_train_loss": 873.7797139485677,
+ "final_val_loss": 878.2410888671875,
+ "training_time_s": 24.290624618530273
+}
\ No newline at end of file
diff --git a/output/deep_benchmark_v2/results/combined_v2.json b/output/deep_benchmark_v2/results/combined_v2.json
new file mode 100644
index 0000000000000000000000000000000000000000..b44a5b2ed42e3d55d1002d3b4d1e53888f02e866
--- /dev/null
+++ b/output/deep_benchmark_v2/results/combined_v2.json
@@ -0,0 +1,342 @@
+{
+ "per_dataset": {
+ "pancreas": {
+ "dataset": "pancreas",
+ "n_epochs": 100,
+ "time_s": 1058.0878033638,
+ "enrichment": {
+ "ARE": {
+ "analytical": {
+ "p_value": 0.9841054448243868,
+ "n_genes_in_set": 14,
+ "median_gamma_in": 0.0,
+ "median_gamma_bg": 0.006473083980381489
+ },
+ "hybrid_deepptr": {
+ "p_value": 0.8696075799919176,
+ "n_genes_in_set": 4,
+ "median_gamma_in": 0.15123695135116577,
+ "median_gamma_bg": 0.5739089846611023
+ }
+ },
+ "NMD": {
+ "analytical": {
+ "p_value": 0.31160184709114613,
+ "n_genes_in_set": 29,
+ "median_gamma_in": 0.0036936448886990547,
+ "median_gamma_bg": 0.006401660852134228
+ },
+ "hybrid_deepptr": {
+ "p_value": 0.5626224403496046,
+ "n_genes_in_set": 16,
+ "median_gamma_in": 0.44641411304473877,
+ "median_gamma_bg": 0.5732103586196899
+ }
+ }
+ },
+ "celltype_agreement": [
+ {
+ "cell_type": "Alpha",
+ "n_cells_an": 481,
+ "n_cells_dp": 481,
+ "n_genes": 272,
+ "spearman_r": 0.9849840305125739
+ },
+ {
+ "cell_type": "Beta",
+ "n_cells_an": 591,
+ "n_cells_dp": 591,
+ "n_genes": 271,
+ "spearman_r": 0.9889437570846297
+ },
+ {
+ "cell_type": "Delta",
+ "n_cells_an": 70,
+ "n_cells_dp": 70,
+ "n_genes": 265,
+ "spearman_r": 0.9755626201008525
+ },
+ {
+ "cell_type": "Ductal",
+ "n_cells_an": 916,
+ "n_cells_dp": 916,
+ "n_genes": 243,
+ "spearman_r": 0.9851671207856005
+ },
+ {
+ "cell_type": "Epsilon",
+ "n_cells_an": 142,
+ "n_cells_dp": 142,
+ "n_genes": 269,
+ "spearman_r": 0.9825605553397818
+ },
+ {
+ "cell_type": "Ngn3 high EP",
+ "n_cells_an": 642,
+ "n_cells_dp": 642,
+ "n_genes": 257,
+ "spearman_r": 0.9788268595602208
+ },
+ {
+ "cell_type": "Ngn3 low EP",
+ "n_cells_an": 262,
+ "n_cells_dp": 262,
+ "n_genes": 243,
+ "spearman_r": 0.9875966152667593
+ },
+ {
+ "cell_type": "Pre-endocrine",
+ "n_cells_an": 592,
+ "n_cells_dp": 592,
+ "n_genes": 269,
+ "spearman_r": 0.9832497980974927
+ }
+ ],
+ "uncertainty": {
+ "var_error_spearman_r": 0.9683824423893881,
+ "var_error_spearman_p": 7.848856686887698e-165,
+ "n_genes": 272,
+ "bin_median_var": [
+ 2.6977049856213853e-06,
+ 6.103933992562816e-05,
+ 0.00129510962869972,
+ 0.00978328101336956,
+ 0.12321395426988602
+ ],
+ "bin_median_error": [
+ 1.4680728912353516,
+ 8.11591625213623,
+ 38.67870330810547,
+ 107.40599060058594,
+ 243.96734619140625
+ ]
+ },
+ "latent_structure": {
+ "silhouette_z_T": 0.2205258160829544,
+ "silhouette_z_PT": -0.009808977134525776,
+ "silhouette_gamma": -0.11721337586641312
+ },
+ "gene_ranking": {
+ "n_shared_genes": 300,
+ "top_median_overlap": 20,
+ "top_median_overlap_frac": 0.4,
+ "top_var_overlap": 34,
+ "top_var_overlap_frac": 0.68,
+ "rank_correlation": 0.5066891652362127
+ }
+ },
+ "dentate_gyrus": {
+ "dataset": "dentate_gyrus",
+ "n_epochs": 100,
+ "time_s": 694.0770261287689,
+ "enrichment": {
+ "ARE": {
+ "analytical": {
+ "p_value": 0.9358900987906894,
+ "n_genes_in_set": 5,
+ "median_gamma_in": 0.0,
+ "median_gamma_bg": 0.0
+ },
+ "hybrid_deepptr": {
+ "p_value": NaN,
+ "n_genes_in_set": 0,
+ "median_gamma_in": NaN,
+ "median_gamma_bg": NaN
+ }
+ },
+ "NMD": {
+ "analytical": {
+ "p_value": 0.007296768008887519,
+ "n_genes_in_set": 11,
+ "median_gamma_in": 0.43911683559417725,
+ "median_gamma_bg": 0.0
+ },
+ "hybrid_deepptr": {
+ "p_value": 0.03924005081735492,
+ "n_genes_in_set": 7,
+ "median_gamma_in": 1.0233218669891357,
+ "median_gamma_bg": 0.4459204375743866
+ }
+ }
+ },
+ "celltype_agreement": [
+ {
+ "cell_type": "Astrocytes",
+ "n_cells_an": 120,
+ "n_cells_dp": 120,
+ "n_genes": 139,
+ "spearman_r": 0.9282586353277625
+ },
+ {
+ "cell_type": "Cajal Retzius",
+ "n_cells_an": 34,
+ "n_cells_dp": 34,
+ "n_genes": 194,
+ "spearman_r": 0.951966734189906
+ },
+ {
+ "cell_type": "Cck-Tox",
+ "n_cells_an": 27,
+ "n_cells_dp": 27,
+ "n_genes": 270,
+ "spearman_r": 0.9701510918454908
+ },
+ {
+ "cell_type": "Endothelial",
+ "n_cells_an": 87,
+ "n_cells_dp": 87,
+ "n_genes": 187,
+ "spearman_r": 0.9376658506417481
+ },
+ {
+ "cell_type": "GABA",
+ "n_cells_an": 61,
+ "n_cells_dp": 61,
+ "n_genes": 282,
+ "spearman_r": 0.9764516140252212
+ },
+ {
+ "cell_type": "Granule immature",
+ "n_cells_an": 785,
+ "n_cells_dp": 785,
+ "n_genes": 286,
+ "spearman_r": 0.991680719793685
+ },
+ {
+ "cell_type": "Granule mature",
+ "n_cells_an": 1070,
+ "n_cells_dp": 1070,
+ "n_genes": 282,
+ "spearman_r": 0.9910605281865464
+ },
+ {
+ "cell_type": "Microglia",
+ "n_cells_an": 81,
+ "n_cells_dp": 81,
+ "n_genes": 96,
+ "spearman_r": 0.9446418882257189
+ },
+ {
+ "cell_type": "Mossy",
+ "n_cells_an": 75,
+ "n_cells_dp": 75,
+ "n_genes": 282,
+ "spearman_r": 0.9759063415615609
+ },
+ {
+ "cell_type": "Neuroblast",
+ "n_cells_an": 417,
+ "n_cells_dp": 417,
+ "n_genes": 245,
+ "spearman_r": 0.9671217227394759
+ },
+ {
+ "cell_type": "OL",
+ "n_cells_an": 50,
+ "n_cells_dp": 50,
+ "n_genes": 140,
+ "spearman_r": 0.9271478865539788
+ },
+ {
+ "cell_type": "OPC",
+ "n_cells_an": 53,
+ "n_cells_dp": 53,
+ "n_genes": 170,
+ "spearman_r": 0.9368958421113697
+ },
+ {
+ "cell_type": "Radial Glia-like",
+ "n_cells_an": 51,
+ "n_cells_dp": 51,
+ "n_genes": 138,
+ "spearman_r": 0.9399528298655901
+ },
+ {
+ "cell_type": "nIPC",
+ "n_cells_an": 19,
+ "n_cells_dp": 19,
+ "n_genes": 183,
+ "spearman_r": 0.9286732511964161
+ }
+ ],
+ "uncertainty": {
+ "var_error_spearman_r": 0.9442975955790626,
+ "var_error_spearman_p": 3.0595371213572223e-135,
+ "n_genes": 278,
+ "bin_median_var": [
+ 3.0064077236602316e-06,
+ 0.0005680265021510422,
+ 0.005993897560983896,
+ 0.028587721288204193,
+ 0.0789710134267807
+ ],
+ "bin_median_error": [
+ 0.21611608564853668,
+ 2.4018590450286865,
+ 9.262259483337402,
+ 21.739778518676758,
+ 53.096153259277344
+ ]
+ },
+ "latent_structure": {
+ "silhouette_z_T": 0.18228954076766968,
+ "silhouette_z_PT": 0.036660902202129364,
+ "silhouette_gamma": -0.08321909606456757
+ },
+ "gene_ranking": {
+ "n_shared_genes": 300,
+ "top_median_overlap": 30,
+ "top_median_overlap_frac": 0.6,
+ "top_var_overlap": 21,
+ "top_var_overlap_frac": 0.42,
+ "rank_correlation": 0.6159207216683028
+ }
+ }
+ },
+ "cross_dataset": {
+ "analytical": [
+ {
+ "dataset_a": "dentate_gyrus",
+ "dataset_b": "pancreas",
+ "n_shared_genes": 4915,
+ "spearman_r": 0.1915326245338796,
+ "pearson_r": 0.1037985123384687
+ }
+ ],
+ "deepptr": [
+ {
+ "dataset_a": "dentate_gyrus",
+ "dataset_b": "pancreas",
+ "n_shared_genes": 53,
+ "spearman_r": 0.7214965328172875,
+ "pearson_r": 0.6869671266770031
+ }
+ ]
+ },
+ "subsampling": {
+ "pancreas": [
+ {
+ "fraction": 0.5,
+ "n_cells": 1848,
+ "spearman_r": 0.9991751019455771
+ },
+ {
+ "fraction": 0.8,
+ "n_cells": 2956,
+ "spearman_r": 0.9997239969332992
+ }
+ ],
+ "dentate_gyrus": [
+ {
+ "fraction": 0.5,
+ "n_cells": 1465,
+ "spearman_r": 0.997867531861465
+ },
+ {
+ "fraction": 0.8,
+ "n_cells": 2344,
+ "spearman_r": 0.9994866609628995
+ }
+ ]
+ }
+}
\ No newline at end of file
diff --git a/output/deep_benchmark_v2/results/dentate_gyrus_v2.json b/output/deep_benchmark_v2/results/dentate_gyrus_v2.json
new file mode 100644
index 0000000000000000000000000000000000000000..1ac4cb8e6b783cad96ec80ca4c686cc22e0a4c79
--- /dev/null
+++ b/output/deep_benchmark_v2/results/dentate_gyrus_v2.json
@@ -0,0 +1,167 @@
+{
+ "dataset": "dentate_gyrus",
+ "n_epochs": 100,
+ "time_s": 694.0770261287689,
+ "enrichment": {
+ "ARE": {
+ "analytical": {
+ "p_value": 0.9358900987906894,
+ "n_genes_in_set": 5,
+ "median_gamma_in": 0.0,
+ "median_gamma_bg": 0.0
+ },
+ "hybrid_deepptr": {
+ "p_value": NaN,
+ "n_genes_in_set": 0,
+ "median_gamma_in": NaN,
+ "median_gamma_bg": NaN
+ }
+ },
+ "NMD": {
+ "analytical": {
+ "p_value": 0.007296768008887519,
+ "n_genes_in_set": 11,
+ "median_gamma_in": 0.43911683559417725,
+ "median_gamma_bg": 0.0
+ },
+ "hybrid_deepptr": {
+ "p_value": 0.03924005081735492,
+ "n_genes_in_set": 7,
+ "median_gamma_in": 1.0233218669891357,
+ "median_gamma_bg": 0.4459204375743866
+ }
+ }
+ },
+ "celltype_agreement": [
+ {
+ "cell_type": "Astrocytes",
+ "n_cells_an": 120,
+ "n_cells_dp": 120,
+ "n_genes": 139,
+ "spearman_r": 0.9282586353277625
+ },
+ {
+ "cell_type": "Cajal Retzius",
+ "n_cells_an": 34,
+ "n_cells_dp": 34,
+ "n_genes": 194,
+ "spearman_r": 0.951966734189906
+ },
+ {
+ "cell_type": "Cck-Tox",
+ "n_cells_an": 27,
+ "n_cells_dp": 27,
+ "n_genes": 270,
+ "spearman_r": 0.9701510918454908
+ },
+ {
+ "cell_type": "Endothelial",
+ "n_cells_an": 87,
+ "n_cells_dp": 87,
+ "n_genes": 187,
+ "spearman_r": 0.9376658506417481
+ },
+ {
+ "cell_type": "GABA",
+ "n_cells_an": 61,
+ "n_cells_dp": 61,
+ "n_genes": 282,
+ "spearman_r": 0.9764516140252212
+ },
+ {
+ "cell_type": "Granule immature",
+ "n_cells_an": 785,
+ "n_cells_dp": 785,
+ "n_genes": 286,
+ "spearman_r": 0.991680719793685
+ },
+ {
+ "cell_type": "Granule mature",
+ "n_cells_an": 1070,
+ "n_cells_dp": 1070,
+ "n_genes": 282,
+ "spearman_r": 0.9910605281865464
+ },
+ {
+ "cell_type": "Microglia",
+ "n_cells_an": 81,
+ "n_cells_dp": 81,
+ "n_genes": 96,
+ "spearman_r": 0.9446418882257189
+ },
+ {
+ "cell_type": "Mossy",
+ "n_cells_an": 75,
+ "n_cells_dp": 75,
+ "n_genes": 282,
+ "spearman_r": 0.9759063415615609
+ },
+ {
+ "cell_type": "Neuroblast",
+ "n_cells_an": 417,
+ "n_cells_dp": 417,
+ "n_genes": 245,
+ "spearman_r": 0.9671217227394759
+ },
+ {
+ "cell_type": "OL",
+ "n_cells_an": 50,
+ "n_cells_dp": 50,
+ "n_genes": 140,
+ "spearman_r": 0.9271478865539788
+ },
+ {
+ "cell_type": "OPC",
+ "n_cells_an": 53,
+ "n_cells_dp": 53,
+ "n_genes": 170,
+ "spearman_r": 0.9368958421113697
+ },
+ {
+ "cell_type": "Radial Glia-like",
+ "n_cells_an": 51,
+ "n_cells_dp": 51,
+ "n_genes": 138,
+ "spearman_r": 0.9399528298655901
+ },
+ {
+ "cell_type": "nIPC",
+ "n_cells_an": 19,
+ "n_cells_dp": 19,
+ "n_genes": 183,
+ "spearman_r": 0.9286732511964161
+ }
+ ],
+ "uncertainty": {
+ "var_error_spearman_r": 0.9442975955790626,
+ "var_error_spearman_p": 3.0595371213572223e-135,
+ "n_genes": 278,
+ "bin_median_var": [
+ 3.0064077236602316e-06,
+ 0.0005680265021510422,
+ 0.005993897560983896,
+ 0.028587721288204193,
+ 0.0789710134267807
+ ],
+ "bin_median_error": [
+ 0.21611608564853668,
+ 2.4018590450286865,
+ 9.262259483337402,
+ 21.739778518676758,
+ 53.096153259277344
+ ]
+ },
+ "latent_structure": {
+ "silhouette_z_T": 0.18228954076766968,
+ "silhouette_z_PT": 0.036660902202129364,
+ "silhouette_gamma": -0.08321909606456757
+ },
+ "gene_ranking": {
+ "n_shared_genes": 300,
+ "top_median_overlap": 30,
+ "top_median_overlap_frac": 0.6,
+ "top_var_overlap": 21,
+ "top_var_overlap_frac": 0.42,
+ "rank_correlation": 0.6159207216683028
+ }
+}
\ No newline at end of file
diff --git a/output/deep_benchmark_v2/results/pancreas_v2.json b/output/deep_benchmark_v2/results/pancreas_v2.json
new file mode 100644
index 0000000000000000000000000000000000000000..84316bb248336505526158965b1e56afa1813786
--- /dev/null
+++ b/output/deep_benchmark_v2/results/pancreas_v2.json
@@ -0,0 +1,125 @@
+{
+ "dataset": "pancreas",
+ "n_epochs": 100,
+ "time_s": 1058.0878033638,
+ "enrichment": {
+ "ARE": {
+ "analytical": {
+ "p_value": 0.9841054448243868,
+ "n_genes_in_set": 14,
+ "median_gamma_in": 0.0,
+ "median_gamma_bg": 0.006473083980381489
+ },
+ "hybrid_deepptr": {
+ "p_value": 0.8696075799919176,
+ "n_genes_in_set": 4,
+ "median_gamma_in": 0.15123695135116577,
+ "median_gamma_bg": 0.5739089846611023
+ }
+ },
+ "NMD": {
+ "analytical": {
+ "p_value": 0.31160184709114613,
+ "n_genes_in_set": 29,
+ "median_gamma_in": 0.0036936448886990547,
+ "median_gamma_bg": 0.006401660852134228
+ },
+ "hybrid_deepptr": {
+ "p_value": 0.5626224403496046,
+ "n_genes_in_set": 16,
+ "median_gamma_in": 0.44641411304473877,
+ "median_gamma_bg": 0.5732103586196899
+ }
+ }
+ },
+ "celltype_agreement": [
+ {
+ "cell_type": "Alpha",
+ "n_cells_an": 481,
+ "n_cells_dp": 481,
+ "n_genes": 272,
+ "spearman_r": 0.9849840305125739
+ },
+ {
+ "cell_type": "Beta",
+ "n_cells_an": 591,
+ "n_cells_dp": 591,
+ "n_genes": 271,
+ "spearman_r": 0.9889437570846297
+ },
+ {
+ "cell_type": "Delta",
+ "n_cells_an": 70,
+ "n_cells_dp": 70,
+ "n_genes": 265,
+ "spearman_r": 0.9755626201008525
+ },
+ {
+ "cell_type": "Ductal",
+ "n_cells_an": 916,
+ "n_cells_dp": 916,
+ "n_genes": 243,
+ "spearman_r": 0.9851671207856005
+ },
+ {
+ "cell_type": "Epsilon",
+ "n_cells_an": 142,
+ "n_cells_dp": 142,
+ "n_genes": 269,
+ "spearman_r": 0.9825605553397818
+ },
+ {
+ "cell_type": "Ngn3 high EP",
+ "n_cells_an": 642,
+ "n_cells_dp": 642,
+ "n_genes": 257,
+ "spearman_r": 0.9788268595602208
+ },
+ {
+ "cell_type": "Ngn3 low EP",
+ "n_cells_an": 262,
+ "n_cells_dp": 262,
+ "n_genes": 243,
+ "spearman_r": 0.9875966152667593
+ },
+ {
+ "cell_type": "Pre-endocrine",
+ "n_cells_an": 592,
+ "n_cells_dp": 592,
+ "n_genes": 269,
+ "spearman_r": 0.9832497980974927
+ }
+ ],
+ "uncertainty": {
+ "var_error_spearman_r": 0.9683824423893881,
+ "var_error_spearman_p": 7.848856686887698e-165,
+ "n_genes": 272,
+ "bin_median_var": [
+ 2.6977049856213853e-06,
+ 6.103933992562816e-05,
+ 0.00129510962869972,
+ 0.00978328101336956,
+ 0.12321395426988602
+ ],
+ "bin_median_error": [
+ 1.4680728912353516,
+ 8.11591625213623,
+ 38.67870330810547,
+ 107.40599060058594,
+ 243.96734619140625
+ ]
+ },
+ "latent_structure": {
+ "silhouette_z_T": 0.2205258160829544,
+ "silhouette_z_PT": -0.009808977134525776,
+ "silhouette_gamma": -0.11721337586641312
+ },
+ "gene_ranking": {
+ "n_shared_genes": 300,
+ "top_median_overlap": 20,
+ "top_median_overlap_frac": 0.4,
+ "top_var_overlap": 34,
+ "top_var_overlap_frac": 0.68,
+ "rank_correlation": 0.5066891652362127
+ }
+}
\ No newline at end of file
diff --git a/output/deep_benchmark_v2/results/subsampling_robustness.json b/output/deep_benchmark_v2/results/subsampling_robustness.json
new file mode 100644
index 0000000000000000000000000000000000000000..f8e01aae2f3cd8a96be23de8dff73f73d8025fe2
--- /dev/null
+++ b/output/deep_benchmark_v2/results/subsampling_robustness.json
@@ -0,0 +1,26 @@
+{
+ "pancreas": [
+ {
+ "fraction": 0.5,
+ "n_cells": 1848,
+ "spearman_r": 0.9991751019455771
+ },
+ {
+ "fraction": 0.8,
+ "n_cells": 2956,
+ "spearman_r": 0.9997239969332992
+ }
+ ],
+ "dentate_gyrus": [
+ {
+ "fraction": 0.5,
+ "n_cells": 1465,
+ "spearman_r": 0.997867531861465
+ },
+ {
+ "fraction": 0.8,
+ "n_cells": 2344,
+ "spearman_r": 0.9994866609628995
+ }
+ ]
+}
\ No newline at end of file
diff --git a/output/deep_benchmarks/02_bootstrap_ci/figures/bootstrap_ci.png b/output/deep_benchmarks/02_bootstrap_ci/figures/bootstrap_ci.png
new file mode 100644
index 0000000000000000000000000000000000000000..8e56d7a42dc65d30411727b27a948fe9c3939e15
Binary files /dev/null and b/output/deep_benchmarks/02_bootstrap_ci/figures/bootstrap_ci.png differ
diff --git a/output/deep_benchmarks/20_uncertainty_advantage/results/uncertainty_advantage.json b/output/deep_benchmarks/20_uncertainty_advantage/results/uncertainty_advantage.json
new file mode 100644
index 0000000000000000000000000000000000000000..d57607ace09b8849f51b7110f805ecc8594bcce8
--- /dev/null
+++ b/output/deep_benchmarks/20_uncertainty_advantage/results/uncertainty_advantage.json
@@ -0,0 +1,76 @@
+{
+ "pancreas": {
+ "analytical_300": {
+ "r": -0.22231279755152644,
+ "n": 219
+ },
+ "deepptr_all": {
+ "r": -0.2767452667406712,
+ "n": 236
+ },
+ "deepptr_filtered": [
+ {
+ "percentile": 75,
+ "r": -0.2935350818803388,
+ "n": 180,
+ "cv_cutoff": 0.11798103153705597
+ },
+ {
+ "percentile": 50,
+ "r": -0.2784230794623337,
+ "n": 120,
+ "cv_cutoff": 0.09954803436994553
+ },
+ {
+ "percentile": 25,
+ "r": -0.3779708509647762,
+ "n": 53,
+ "cv_cutoff": 0.08271166682243347
+ },
+ {
+ "percentile": 10,
+ "r": -0.2781954887218045,
+ "n": 20,
+ "cv_cutoff": 0.05375545844435692
+ }
+ ],
+ "improvement": 0.15565805341324973
+ },
+ "dentate_gyrus": {
+ "analytical_300": {
+ "r": -0.3593371092867718,
+ "n": 199
+ },
+ "deepptr_all": {
+ "r": -0.35768791768630437,
+ "n": 211
+ },
+ "deepptr_filtered": [
+ {
+ "percentile": 75,
+ "r": -0.4037010444550779,
+ "n": 159,
+ "cv_cutoff": 0.13886773586273193
+ },
+ {
+ "percentile": 50,
+ "r": -0.3379248062565652,
+ "n": 100,
+ "cv_cutoff": 0.11725422739982605
+ },
+ {
+ "percentile": 25,
+ "r": -0.10556391748122433,
+ "n": 49,
+ "cv_cutoff": 0.0847647488117218
+ },
+ {
+ "percentile": 10,
+ "r": 0.004511278195488721,
+ "n": 20,
+ "cv_cutoff": 0.029071299359202385
+ }
+ ],
+ "improvement": 0.04436393516830606
+ }
+}
\ No newline at end of file
diff --git a/output/deep_benchmarks/24_fullgenome_gpu/results/fullgenome_gpu.json b/output/deep_benchmarks/24_fullgenome_gpu/results/fullgenome_gpu.json
new file mode 100644
index 0000000000000000000000000000000000000000..029eebd3c83dc9c74ac05e106a039d3ee11622f9
--- /dev/null
+++ b/output/deep_benchmarks/24_fullgenome_gpu/results/fullgenome_gpu.json
@@ -0,0 +1,112 @@
+{
+ "pancreas": [
+ {
+ "n_genes": 300,
+ "label": "300 genes",
+ "device": "cpu",
+ "time_s": 126.28486108779907,
+ "n_epochs": 100,
+ "hl_mouse_r": -0.19762101977653473,
+ "hl_mouse_n": 251,
+ "hl_human_r": -0.2767452667406712,
+ "hl_human_n": 236
+ },
+ {
+ "n_genes": 500,
+ "label": "500 genes",
+ "device": "cpu",
+ "time_s": 195.14217829704285,
+ "n_epochs": 100,
+ "hl_mouse_r": -0.13388556817704766,
+ "hl_mouse_n": 425,
+ "hl_human_r": -0.23868475929802593,
+ "hl_human_n": 405
+ },
+ {
+ "n_genes": 1000,
+ "label": "1000 genes",
+ "device": "cpu",
+ "time_s": 250.388201713562,
+ "n_epochs": 100,
+ "hl_mouse_r": -0.1749767413418925,
+ "hl_mouse_n": 855,
+ "hl_human_r": -0.2701509996732806,
+ "hl_human_n": 828
+ },
+ {
+ "n_genes": 2000,
+ "label": "2000 genes",
+ "device": "cpu",
+ "time_s": 311.9621741771698,
+ "n_epochs": 100,
+ "hl_mouse_r": -0.2015269295525831,
+ "hl_mouse_n": 1732,
+ "hl_human_r": -0.29089533198701906,
+ "hl_human_n": 1653
+ },
+ {
+ "n_genes": 11906,
+ "label": "Analytical (all)",
+ "device": "cpu",
+ "hl_mouse_r": -0.34966929477006137,
+ "hl_human_r": -0.4020872107350974,
+ "hl_mouse_n": 4611,
+ "hl_human_n": 4308
+ }
+ ],
+ "dentate_gyrus": [
+ {
+ "n_genes": 300,
+ "label": "300 genes",
+ "device": "cpu",
+ "time_s": 177.58326506614685,
+ "n_epochs": 100,
+ "hl_mouse_r": -0.2852053996865196,
+ "hl_mouse_n": 216,
+ "hl_human_r": -0.35768791768630437,
+ "hl_human_n": 211
+ },
+ {
+ "n_genes": 500,
+ "label": "500 genes",
+ "device": "cpu",
+ "time_s": 101.45515847206116,
+ "n_epochs": 100,
+ "hl_mouse_r": -0.32213690425879954,
+ "hl_mouse_n": 380,
+ "hl_human_r": -0.3782651711359226,
+ "hl_human_n": 361
+ },
+ {
+ "n_genes": 1000,
+ "label": "1000 genes",
+ "device": "cpu",
+ "time_s": 215.91462779045105,
+ "n_epochs": 100,
+ "hl_mouse_r": -0.3366768487779157,
+ "hl_mouse_n": 807,
+ "hl_human_r": -0.3801130440429436,
+ "hl_human_n": 752
+ },
+ {
+ "n_genes": 2000,
+ "label": "2000 genes",
+ "device": "cpu",
+ "time_s": 244.55135011672974,
+ "n_epochs": 100,
+ "hl_mouse_r": -0.3052852382518734,
+ "hl_mouse_n": 1681,
+ "hl_human_r": -0.3678329895976058,
+ "hl_human_n": 1542
+ },
+ {
+ "n_genes": 5325,
+ "label": "Analytical (all)",
+ "device": "cpu",
+ "hl_mouse_r": -0.3179587682344816,
+ "hl_human_r": -0.3812073018847205,
+ "hl_mouse_n": 1217,
+ "hl_human_n": 1126
+ }
+ ]
+}
\ No newline at end of file
diff --git a/output/figures/aim1/enrichment_barplot.png b/output/figures/aim1/enrichment_barplot.png
new file mode 100644
index 0000000000000000000000000000000000000000..6db74a167634baf094f87697ea8118a7d6236de2
Binary files /dev/null and b/output/figures/aim1/enrichment_barplot.png differ
diff --git a/output/figures/aim1/subsampling_robustness.png b/output/figures/aim1/subsampling_robustness.png
new file mode 100644
index 0000000000000000000000000000000000000000..22fa6d96a4dea617b2aad9dc3bcedda0bc60e88e
Binary files /dev/null and b/output/figures/aim1/subsampling_robustness.png differ
diff --git a/output/figures/aim2/gamma_heatmap.png b/output/figures/aim2/gamma_heatmap.png
new file mode 100644
index 0000000000000000000000000000000000000000..201f3ae99236e90a11e9a1c001bbe40e23c6af0b
Binary files /dev/null and b/output/figures/aim2/gamma_heatmap.png differ
diff --git a/output/figures/aim2/tf_ptf_scatter.png b/output/figures/aim2/tf_ptf_scatter.png
new file mode 100644
index 0000000000000000000000000000000000000000..4ff09ae618fd7a211a8e67c06686bd5d0666c56f
Binary files /dev/null and b/output/figures/aim2/tf_ptf_scatter.png differ
diff --git a/output/gap_analysis/figures/network/network_dentate_gyrus.png b/output/gap_analysis/figures/network/network_dentate_gyrus.png
new file mode 100644
index 0000000000000000000000000000000000000000..d0737a1ab16b43b19bfbfe01cfe1abe0c6501f42
Binary files /dev/null and b/output/gap_analysis/figures/network/network_dentate_gyrus.png differ
diff --git a/output/gap_analysis/results/invisible_states/dentate_gyrus/invisible_states.csv b/output/gap_analysis/results/invisible_states/dentate_gyrus/invisible_states.csv
new file mode 100644
index 0000000000000000000000000000000000000000..63b54be6daeca8d096d27ee7755c10a61bb18d1d
--- /dev/null
+++ b/output/gap_analysis/results/invisible_states/dentate_gyrus/invisible_states.csv
@@ -0,0 +1,12 @@
+cluster,n_cells,n_subclusters,silhouette_gamma,silhouette_expr,invisibility_score,combined_p,top_diff_genes
+Astrocytes,120,2,0.2716423273086548,0.22705544531345367,0.04458688199520111,0.0,"['Cnot6', 'Nlgn1', 'Pnpla7', 'Vmp1', 'Scfd1', 'Kcnd2', 'Hlcs', 'Lrp1b', 'Pcdh9', 'Luzp2']"
+Endothelial,87,2,0.3709166646003723,0.6044033765792847,-0.23348671197891235,0.0,"['Pnpla7', 'Dapk1', 'Vmp1', 'Arl15', 'Cnot6', 'Hlcs', 'Prkg1', 'Igf1r', 'Pde7b', 'Plcl1']"
+GABA,61,3,0.24294190108776093,0.20515747368335724,0.037784427404403687,0.0,"['Slc8a1', 'Dapk1', 'Nkain2', 'Kctd16', 'Cnot6', 'Xkr4', 'Nlgn1', 'Slit3', 'Sgcz', 'Fgf14']"
+Granule immature,785,2,0.2173723578453064,0.0045087020844221115,0.21286365576088428,0.0,"['Pnpla7', 'Fgf14', 'Nkain2', 'Dlg2', 'Nlgn1', 'Slit3', 'Cnot6', 'Vmp1', 'Grm7', 'Kctd16']"
+Granule mature,1070,3,0.14220979809761047,-0.040953319519758224,0.1831631176173687,0.0,"['Fgf14', 'Pnpla7', 'Kctd16', 'Dlg2', 'Nlgn1', 'Nkain2', 'Slit3', 'Cnot6', 'Vmp1', 'Fam155a']"
+Microglia,81,2,0.3435395658016205,0.03644650802016258,0.3070930577814579,0.0,"['Pnpla7', 'Cnot6', 'Vmp1', 'Maml3', 'Rab39', 'Plcl1', 'Scfd1', 'Rmdn1', 'Nav3', 'Clic4']"
+Mossy,75,3,0.277706503868103,0.21522463858127594,0.06248186528682709,0.0,"['Pnpla7', 'Hs6st3', 'Nkain2', 'Dlg2', 'Kctd16', 'Rgs7', 'Xkr4', 'Cacnb2', 'Slit3', 'Fgf14']"
+Neuroblast,417,2,0.3091459274291992,0.32825586199760437,-0.01910993456840515,0.0,"['Pnpla7', 'Cnot6', 'Nlgn1', 'Dapk1', 'Nkain2', 'Slit3', 'Fgf14', 'Rgs7', 'Dlg2', 'Vmp1']"
+OL,50,2,0.36671721935272217,0.14149659872055054,0.22522062063217163,0.0,"['Nkain2', 'Pnpla7', 'Plcl1', 'Ncam2', 'Spock1', 'Ptprk', 'Lrp1b', 'Chka', 'Dapk1', 'Cnot6']"
+OPC,53,2,0.39298373460769653,0.1758575141429901,0.21712622046470642,0.0,"['Nlgn1', 'Pnpla7', 'Cnot6', 'Dapk1', 'Sgcz', 'Ncam2', 'Fam155a', 'Kcnd2', 'Mmp16', 'Luzp2']"
+Radial Glia-like,51,2,0.30975162982940674,0.02847418375313282,0.2812774460762739,1.1102230246251565e-16,"['Nlgn1', 'Pnpla7', 'Cnot6', 'Scfd1', 'Vmp1', 'Lsamp', 'Cdyl2', 'Fgf14', 'Apba1', 'Erc2']"
diff --git a/output/gap_analysis/results/invisible_states/pancreas/invisible_states.csv b/output/gap_analysis/results/invisible_states/pancreas/invisible_states.csv
new file mode 100644
index 0000000000000000000000000000000000000000..88cec5e0543eb402fd311cfc5f1baa90d15bcdf6
--- /dev/null
+++ b/output/gap_analysis/results/invisible_states/pancreas/invisible_states.csv
@@ -0,0 +1,9 @@
+cluster,n_cells,n_subclusters,silhouette_gamma,silhouette_expr,invisibility_score,combined_p,top_diff_genes
+Alpha,481,2,0.15257549285888672,0.18451890349388123,-0.03194341063499451,0.0,"['Ptprn2', 'Cacnb2', 'Pde4d', 'Hs6st3', 'Tmtc2', 'Park2', 'Airn', 'Rora', 'Wwox', 'Cacna1a']"
+Beta,591,2,0.1581832617521286,0.2098182886838913,-0.051635026931762695,0.0,"['Cacnb2', 'Ptprn2', 'Grip1', 'Rora', 'Sntg1', 'Tmtc2', 'Fam155a', 'Airn', 'Phactr1', 'Rabgef1']"
+Delta,70,2,0.27680444717407227,0.13608261942863464,0.14072182774543762,0.0,"['Hs6st3', 'Rora', 'Tmtc2', 'Ptprn2', 'Park2', 'Cacna1c', 'Fhit', 'Snd1', 'Psmd13', 'Dennd1a']"
+Ductal,916,2,0.1913653016090393,0.30966684222221375,-0.11830154061317444,0.0,"['Kalrn', 'Naaladl2', 'Psmd13', 'Kcnh7', 'Traf5', 'Mecom', 'Pkhd1', 'Tmtc2', '9030622O22Rik', 'Wwox']"
+Epsilon,142,3,0.19315549731254578,-0.05613249912858009,0.24928799644112587,0.0,"['Ptprn2', '9030622O22Rik', 'Nrg1', 'Cacna1c', 'Slc8a1', 'Cacnb2', 'Kalrn', 'Sorcs1', 'Nedd8', 'Nr6a1']"
+Ngn3 high EP,642,2,0.2596045136451721,0.20566286146640778,0.05394165217876434,0.0,"['Adgrb3', 'Airn', 'Ptprn2', 'Kalrn', '9030622O22Rik', 'Nedd8', 'Cacna1a', 'Kcnb2', 'Kcnh7', 'Arl15']"
+Ngn3 low EP,262,2,0.1923951506614685,0.28167375922203064,-0.08927860856056213,0.0,"['Kcnh7', 'Airn', 'Ptprj', 'Macrod2', 'Nedd8', 'Ttll3', 'Pkhd1', '9030622O22Rik', 'Psmd13', 'Tecpr2']"
+Pre-endocrine,592,2,0.14428557455539703,0.06477079540491104,0.07951477915048599,0.0,"['Ptprn2', 'Adgrb3', 'Cacnb2', 'Cacna1a', 'Sdk1', 'Maml3', 'Pbx1', 'Wwox', 'Stxbp5l', 'Kcnb2']"
diff --git a/output/gap_analysis/results/network/dentate_gyrus/rbp_hub_counts.csv b/output/gap_analysis/results/network/dentate_gyrus/rbp_hub_counts.csv
new file mode 100644
index 0000000000000000000000000000000000000000..1c431e9686e79044e6f04a1124396ea9f265c797
--- /dev/null
+++ b/output/gap_analysis/results/network/dentate_gyrus/rbp_hub_counts.csv
@@ -0,0 +1,31 @@
+rbp,0
+Ybx1,550
+Rbfox1,230
+Celf2,214
+Hnrnpa1,209
+Rbfox3,197
+Elavl3,194
+Rbfox2,143
+Matr3,134
+Elavl1,129
+Mbnl2,118
+Hnrnpc,109
+Celf1,102
+Fto,80
+Tia1,74
+Elavl4,73
+Ptbp2,64
+Ago2,63
+Pum1,58
+Khdrbs1,55
+Stau2,44
+Msi1,35
+Cirbp,34
+Cnot1,33
+Mbnl1,28
+Ythdf2,23
+Nova1,22
+Igf2bp3,15
+Dis3l2,11
+Mettl3,8
+Xrn1,1
diff --git a/output/gap_analysis/results/network/pancreas/network_edges.csv b/output/gap_analysis/results/network/pancreas/network_edges.csv
new file mode 100644
index 0000000000000000000000000000000000000000..5235223dd0308460a76df55614836e9151e754d8
--- /dev/null
+++ b/output/gap_analysis/results/network/pancreas/network_edges.csv
@@ -0,0 +1,1113 @@
+cluster,rbp,target,spearman_r,p_value,direction,fdr
+Alpha,Elavl2,Cdh6,0.26203343794974154,5.407028620743206e-09,destabilizing,1.6338629962680558e-08
+Alpha,Elavl2,Megf11,0.26203343794974154,5.407028620743206e-09,destabilizing,1.6338629962680558e-08
+Alpha,Elavl3,Cdh6,0.3803405513252895,5.291227254221808e-18,destabilizing,6.395483376842011e-17
+Alpha,Elavl3,Megf11,0.3803405513252895,5.291227254221808e-18,destabilizing,6.395483376842011e-17
+Alpha,Hnrnpa1,Atp2c1,0.22413725854302474,6.826094840914355e-07,destabilizing,1.6013960892609204e-06
+Alpha,Mbnl2,Gm14325,0.2038197635425218,6.610147262562782e-06,destabilizing,1.4441028990117513e-05
+Alpha,Rbfox1,Cdh6,1.0,0.0,destabilizing,0.0
+Alpha,Rbfox1,Megf11,1.0,0.0,destabilizing,0.0
+Alpha,Ybx1,Hs6st3,-0.22466593227895648,6.415531970766755e-07,stabilizing,1.514664872928372e-06
+Alpha,Ybx1,Magi1,0.21279301166122702,2.4916949982750075e-06,destabilizing,5.586219431616549e-06
+Alpha,Ybx1,Atrnl1,0.21526649144204385,1.8899021492807361e-06,destabilizing,4.271486158536948e-06
+Alpha,Ybx1,Pcdh9,-0.20703609478252408,4.6822819224148085e-06,stabilizing,1.0330749003423148e-05
+Alpha,Ybx1,Elovl1,0.2624604192944242,5.096538107223685e-09,destabilizing,1.552698732940476e-08
+Alpha,Ybx1,Robo2,0.23439348398462315,1.9940860891253159e-07,destabilizing,5.016795771736089e-07
+Alpha,Ybx1,Auts2,0.2561244996445355,1.2125683618869752e-08,destabilizing,3.52978015292753e-08
+Alpha,Ybx1,Tbc1d5,0.2447804844855237,5.405710324406228e-08,destabilizing,1.4733210492009133e-07
+Alpha,Ybx1,Pnp,0.206381184070519,5.025068531282381e-06,destabilizing,1.1043233610249027e-05
+Alpha,Ybx1,Bcas3,0.21836993739542246,1.329841879450396e-06,destabilizing,3.024098507052843e-06
+Alpha,Ybx1,Hmg20a,0.23679615186911177,1.4822601637460572e-07,destabilizing,3.815447458531517e-07
+Alpha,Ybx1,Usp29,0.20976148837887812,3.4810470240907114e-06,destabilizing,7.75736330819413e-06
+Beta,Hnrnpa1,Airn,0.20825077793277127,3.254697673145138e-07,destabilizing,7.90223539855326e-07
+Beta,Hnrnpa1,Cacna1a,0.2019374580923898,7.425584105507204e-07,destabilizing,1.7310795650574446e-06
+Beta,Hnrnpa1,Cadps,0.2748431557849476,1.0550344465477105e-11,destabilizing,5.1231367011399746e-11
+Beta,Hnrnpa1,Mcc,-0.2085503264567078,3.1277663716141e-07,stabilizing,7.610670033336716e-07
+Beta,Hnrnpa1,Tenm3,0.21403176252965384,1.494823111251487e-07,destabilizing,3.838899075546544e-07
+Beta,Hnrnpa1,Nbea,0.2201949666159295,6.365000763599169e-08,destabilizing,1.7263124022249454e-07
+Beta,Hnrnpa1,Slit3,-0.20965325986952713,2.700247900281614e-07,stabilizing,6.657817439275288e-07
+Beta,Rbfox3,Sorcs1,0.20078391733810366,8.609359214624169e-07,destabilizing,1.9862256113406796e-06
+Beta,Srsf3,Pkhd1,0.24767593052932624,1.0362285069244614e-09,destabilizing,3.3399597092753652e-09
+Beta,Srsf3,Rora,0.20960091559145153,2.71919774586844e-07,destabilizing,6.689707728773684e-07
+Beta,Ybx1,Ptprn2,0.2749190172863932,1.040834118788792e-11,destabilizing,5.0763488600576175e-11
+Beta,Ybx1,Arl15,0.29334213482195415,3.4162776412279957e-13,destabilizing,2.0873080972777644e-12
+Beta,Ybx1,Rora,0.26906599156181604,2.924855974760069e-11,destabilizing,1.275466605463999e-10
+Beta,Ybx1,Fhit,0.204021563189086,5.671790315081534e-07,destabilizing,1.3505419336982154e-06
+Beta,Ybx1,Kcnb2,0.20753073699483704,3.5804261795526715e-07,destabilizing,8.655291112309937e-07
+Beta,Ybx1,Ptprj,0.21182034759203686,2.0182715842782156e-07,destabilizing,5.066180590784144e-07
+Beta,Ybx1,Glis3,-0.2733484724389614,1.3767287026350834e-11,stabilizing,6.432446711471482e-11
+Beta,Ybx1,Ror1,0.24046884118097764,3.2070659530171125e-09,destabilizing,9.906270388208414e-09
+Beta,Ybx1,Pcdh9,-0.20160311594925673,7.751547456977429e-07,stabilizing,1.7995241695530066e-06
+Beta,Ybx1,Ptprd,0.23753807128691887,5.025608857406882e-09,destabilizing,1.535295892702322e-08
+Beta,Ybx1,Elovl1,0.20565479763583908,4.583200393966738e-07,destabilizing,1.098387680623063e-06
+Beta,Ybx1,Phactr1,0.22793941913489008,2.1004488773537573e-08,destabilizing,5.988972183634303e-08
+Beta,Ybx1,Kcnq1,0.25014522983757104,6.978291606829907e-10,destabilizing,2.3094822222603737e-09
+Beta,Ybx1,Cntnap5b,-0.2113506004449993,2.1502912048080975e-07,stabilizing,5.337329954791528e-07
+Beta,Ybx1,Plekhg1,0.2849146706723274,1.6822839815679224e-12,destabilizing,9.037197041079853e-12
+Beta,Ybx1,Camta1,0.2542461275867855,3.5850671777355343e-10,destabilizing,1.241929813595612e-09
+Beta,Ybx1,Nol12,0.2294339414812183,1.6880427048300965e-08,destabilizing,4.850396609227564e-08
+Delta,Celf1,Park2,0.3452649809012589,0.00341948259622115,destabilizing,0.004097483455816723
+Delta,Cirbp,Pbx1,0.34061243413944353,0.00391079497429091,destabilizing,0.00461817898851616
+Delta,Cirbp,Sdk1,0.3119446264724072,0.00856684689291306,destabilizing,0.008869956931954677
+Delta,Cirbp,Unc5c,0.32508299987780753,0.006034965424226595,destabilizing,0.006758188873856972
+Delta,Cpeb1,Hivep2,0.3816407855662138,0.001114624467569144,destabilizing,0.0014843861172896865
+Delta,Cpeb4,Pawr,-0.36078803920401603,0.002153004143566272,stabilizing,0.0027268116260201537
+Delta,Ddx6,Park2,0.3912120674280215,0.0008118790696458335,destabilizing,0.0011471531454207964
+Delta,Ddx6,9030622O22Rik,-0.31495001554956276,0.007917576815750345,stabilizing,0.008321687541696016
+Delta,Ddx6,Tenm3,-0.309887873021762,0.009037566601990257,stabilizing,0.009245422319607328
+Delta,Dis3l2,Smim10l1,0.32189394171390984,0.006579712966665911,destabilizing,0.007264764616636646
+Delta,Elavl1,Traf5,-0.31252660782466546,0.008437603243490372,stabilizing,0.008752439185411654
+Delta,Elavl1,Pde1c,-0.31154479642696853,0.008656638881014226,stabilizing,0.008937959550313667
+Delta,Elavl4,Ttll3,0.43345898709871045,0.00017801582512283929,destabilizing,0.0003073813626344679
+Delta,Elavl4,Dapk1,0.3096351379708817,0.009096938374555151,destabilizing,0.009297606132817398
+Delta,Elavl4,Fmnl2,0.33285635024926674,0.004870191487746645,destabilizing,0.005635434895290604
+Delta,Esrp1,Nlk,-0.3200840173826809,0.006907728646104382,stabilizing,0.007501753714803198
+Delta,Fmr1,Ambra1,-0.3461564271511151,0.0033318810870504303,stabilizing,0.004009796286580171
+Delta,Fmr1,9530026P05Rik,0.43683378449756527,0.00015631184522717955,destabilizing,0.0002750297023617463
+Delta,Fto,Slc8a1,0.3134145233489583,0.008243703699529585,destabilizing,0.008599435754105909
+Delta,Fto,Nos1ap,0.3134145233489583,0.008243703699529585,destabilizing,0.008599435754105909
+Delta,Fus,Rora,-0.3385697347902681,0.004145625486700181,stabilizing,0.004878238667947726
+Delta,Hnrnpa1,9030622O22Rik,0.3357602306839231,0.004489016341266401,destabilizing,0.005237970799043271
+Delta,Hnrnpa1,Rora,-0.3158869975965165,0.007724167845242967,stabilizing,0.00821154363662541
+Delta,Hnrnpa1,Sdk1,0.3788774332993465,0.0012192829343647676,destabilizing,0.001614098360730502
+Delta,Hnrnpa1,Zfp422,0.3146679442259819,0.007976625493329201,destabilizing,0.008367931649605729
+Delta,Hnrnpa1,Ctnna2,0.3440984200647004,0.003537212949635215,destabilizing,0.004229441720424042
+Delta,Hnrnpa1,Fbxl17,0.3851542963315508,0.0009933032348628187,destabilizing,0.0013453753924085926
+Delta,Hnrnpa1,Cdk14,-0.3239318607219184,0.006226837364805615,stabilizing,0.006931174323987832
+Delta,Hnrnpa1,Auts2,0.3359380298992718,0.004466560710763666,destabilizing,0.005217243183160921
+Delta,Hnrnpa1,Strbp,-0.31068265656005906,0.00885305717742752,stabilizing,0.009115369982684631
+Delta,Hnrnpa1,Ankrd28,0.3134402925067099,0.008238135024705101,destabilizing,0.008599435754105909
+Delta,Hnrnpa2b1,Chchd3,0.35541012216975065,0.002533830719850059,destabilizing,0.0031516999557866503
+Delta,Hnrnpa2b1,Numb,0.3366696927199108,0.0043751971482020695,destabilizing,0.00512667990389958
+Delta,Igf2bp1,Airn,0.3075147043934641,0.009608619500007203,destabilizing,0.009732954111727176
+Delta,Igf2bp3,Scmh1,0.3102872458149304,0.008944436631129878,destabilizing,0.009192433949922758
+Delta,Matr3,Atxn1,-0.3294604102642612,0.005352043922943613,stabilizing,0.006160944971338817
+Delta,Mbnl1,Cacnb2,0.4096732451993513,0.00042866242453469365,destabilizing,0.000666674987528083
+Delta,Mbnl1,9030622O22Rik,-0.3069518459574353,0.009748585708651494,stabilizing,0.009801471345407289
+Delta,Mbnl1,Nrg1,0.4340573661412156,0.00017397611072079611,destabilizing,0.0003008731494891529
+Delta,Mbnl1,Macrod2,0.3563667700147456,0.002461974064319365,destabilizing,0.003065750458592535
+Delta,Mbnl1,Large,0.4340573661412156,0.00017397611072079611,destabilizing,0.0003008731494891529
+Delta,Mbnl1,Magi3,0.4340573661412156,0.00017397611072079611,destabilizing,0.0003008731494891529
+Delta,Mbnl1,Tbc1d5,0.5007675513000452,1.0103712643087108e-05,destabilizing,2.1606400882909353e-05
+Delta,Mbnl1,Med12l,0.31726361167073913,0.0074475209388869534,destabilizing,0.007963118542348359
+Delta,Mbnl1,Numb,0.3721920989392227,0.0015101175891196158,destabilizing,0.0019594524610280196
+Delta,Mbnl1,Fmnl2,0.48893020980794055,1.749689002822437e-05,destabilizing,3.643547136963576e-05
+Delta,Mbnl1,Zyx,0.4340573661412156,0.00017397611072079611,destabilizing,0.0003008731494891529
+Delta,Mbnl1,Arf4,0.40997110351432714,0.0004241389976111874,destabilizing,0.0006624193333478096
+Delta,Mbnl2,2410018L13Rik,-0.3553094419569684,0.0025415011171734778,stabilizing,0.0031577086506110697
+Delta,Mettl14,Sema6a,0.39309747967410885,0.0007618853909171992,destabilizing,0.0010917665398871195
+Delta,Mettl3,Airn,0.33116968165449984,0.005104494348686927,destabilizing,0.005888171904294463
+Delta,Mettl3,Grip1,0.37488734034985655,0.0013860845709374027,destabilizing,0.0018090681254488167
+Delta,Mettl3,2010111I01Rik,0.3869804803611422,0.0009350852934786235,destabilizing,0.0012817508101160993
+Delta,Mettl3,Pcdh9,0.701964118163034,1.2854187925254663e-11,destabilizing,6.056719056306433e-11
+Delta,Mettl3,Ints6,0.3869804803611422,0.0009350852934786235,destabilizing,0.0012817508101160993
+Delta,Mettl3,Rapgef2,0.37488734034985655,0.0013860845709374027,destabilizing,0.0018090681254488167
+Delta,Mettl3,Pdxdc1,0.37488734034985655,0.0013860845709374027,destabilizing,0.0018090681254488167
+Delta,Mettl3,Dnajb11,0.37488734034985655,0.0013860845709374027,destabilizing,0.0018090681254488167
+Delta,Mettl3,Slit3,0.701964118163034,1.2854187925254663e-11,destabilizing,6.056719056306433e-11
+Delta,Msi2,Scmh1,0.3653372369811088,0.0018718175517632991,destabilizing,0.00238426244852324
+Delta,Msi2,Akt3,0.3677452509840374,0.00173673966520387,destabilizing,0.002227513849719381
+Delta,Ptbp1,Glis3,0.3524170113899135,0.0027709200904618364,destabilizing,0.0034122515399707225
+Delta,Ptbp1,2010111I01Rik,0.3164657407932223,0.007606784383956854,destabilizing,0.00810224543578546
+Delta,Ptbp1,Atrnl1,-0.32143266912235885,0.006661982700557882,stabilizing,0.00733477699308947
+Delta,Ptbp1,Robo2,0.3208787271086515,0.006761974117138302,destabilizing,0.007422519840563595
+Delta,Ptbp1,Sox5,0.3216714567722238,0.006619281827311654,destabilizing,0.007294986513350405
+Delta,Ptbp1,Rapgef2,0.3186838290412911,0.0071712541299141196,destabilizing,0.0077196849878649575
+Delta,Ptbp1,Zfp609,0.32767077079670964,0.005622533158270936,destabilizing,0.006373350532107321
+Delta,Ptbp2,Arl15,0.3064312717174004,0.009879615038064556,destabilizing,0.009888507580853093
+Delta,Pum2,Fhit,-0.31789638257397473,0.007323299615641116,stabilizing,0.007860530089375407
+Delta,Rbfox3,Hivep2,0.3246723265062343,0.006102810502427074,destabilizing,0.0068204274157777954
+Delta,Srsf1,Ror1,-0.3551383080508525,0.0025545867289222287,stabilizing,0.0031704246010731234
+Delta,Srsf1,Rapgef4,0.30887970139904,0.009276437462220071,destabilizing,0.009463668310081394
+Delta,Srsf3,Tmem178b,-0.3292509860742576,0.005383091569151579,stabilizing,0.0061735493191160725
+Delta,Srsf3,Shank2,-0.3222057114959706,0.006524614749911109,stabilizing,0.007219275225772291
+Delta,Stau2,Pcdh9,0.33514003129991815,0.0045681308664935975,destabilizing,0.005319122014178932
+Delta,Stau2,Slit3,0.33514003129991815,0.0045681308664935975,destabilizing,0.005319122014178932
+Delta,Tardbp,Ctnna2,0.4213418081860143,0.0002808041671520336,destabilizing,0.0004639736015944448
+Delta,Tardbp,Sox5,0.36316414543428444,0.002001737457776283,destabilizing,0.0025439223463396875
+Delta,Tardbp,Dennd1b,-0.3223348789270687,0.0065019064699404225,stabilizing,0.007201314735631225
+Delta,Tra2b,Arl15,-0.4787206010093414,2.7648586854905834e-05,stabilizing,5.579896294492793e-05
+Delta,Tra2b,Nr6a1,0.30738371546622134,0.009641035219619341,destabilizing,0.009746210149287915
+Delta,Tra2b,Rabgef1,0.3480120913656032,0.003155907973638979,destabilizing,0.0038311895924525593
+Delta,Tra2b,Cacna1c,0.3218623085582224,0.006585326199253363,destabilizing,0.007264764616636646
+Delta,Tra2b,Vti1a,0.35861379484050404,0.0023003128341850566,destabilizing,0.002890675239944147
+Delta,Tra2b,Ctnna2,0.3776152674750232,0.0012699735117018469,destabilizing,0.0016752201008451409
+Delta,Tra2b,Fbxl17,0.3420610121051244,0.003751499792800009,destabilizing,0.004456910010249583
+Delta,Tra2b,Map7,-0.3310635064984956,0.0051195713875654076,stabilizing,0.005899443920178998
+Delta,Tra2b,Kcnq1,-0.3372053380464698,0.004309364441916532,stabilizing,0.005054866307395762
+Delta,Tra2b,Nbea,0.32811154446724267,0.0055548182649376695,destabilizing,0.006315907884060009
+Delta,Tra2b,Asic2,-0.40261444977027794,0.0005496166399499761,stabilizing,0.0008315288484685352
+Delta,Tra2b,Cacna1d,0.5019089903112672,9.572235247007615e-06,destabilizing,2.0509297870274503e-05
+Delta,Tra2b,2410018L13Rik,-0.3458189002907057,0.003364811644837085,stabilizing,0.004045049242225771
+Delta,Tra2b,Gphn,-0.35045384533123575,0.002936992791024829,stabilizing,0.003581070157477642
+Delta,Tra2b,Atp2c1,0.3614261359225247,0.002111407212235962,destabilizing,0.002677177673895541
+Delta,Tra2b,Nol12,-0.4503391640411756,9.162591490071739e-05,stabilizing,0.0001698133622826629
+Delta,Upf1,Nrg1,0.3256694736394648,0.005939229178142408,destabilizing,0.006669513557070419
+Delta,Upf1,Large,0.3256694736394648,0.005939229178142408,destabilizing,0.006669513557070419
+Delta,Upf1,Magi3,0.3256694736394648,0.005939229178142408,destabilizing,0.006669513557070419
+Delta,Upf1,Zyx,0.3256694736394648,0.005939229178142408,destabilizing,0.006669513557070419
+Delta,Xrn1,Tmtc2,-0.3312213075521498,0.0050971775769371565,stabilizing,0.005885837451250382
+Delta,Ybx1,Pbx1,0.30990023304871545,0.009034671716724904,destabilizing,0.009245422319607328
+Delta,Ybx1,Nedd8,-0.3080208860842536,0.009484246322008583,stabilizing,0.009640294250524263
+Delta,Ybx1,Auts2,0.30618763827878476,0.009941463105912242,destabilizing,0.009941463105912242
+Delta,Ybx1,Scmh1,0.3575239600258496,0.0023774937301887437,destabilizing,0.0029716040023304285
+Delta,Ybx1,Cacna2d1,0.31014459933080735,0.008977603799075196,destabilizing,0.009209497624143559
+Delta,Ybx1,Bcas3,0.3073441731060497,0.009650839444466435,destabilizing,0.009747260183693622
+Delta,Ybx1,Akt3,0.3567758726438498,0.0024318056424384228,destabilizing,0.0030349807793395352
+Delta,Ybx1,Nlk,-0.35167859211159685,0.00283237582013937,stabilizing,0.0034763818013189614
+Delta,Zfp36l1,Nrg1,0.32063997863061255,0.00680547538742138,destabilizing,0.0074265835434863346
+Delta,Zfp36l1,Large,0.32063997863061255,0.00680547538742138,destabilizing,0.0074265835434863346
+Delta,Zfp36l1,Magi3,0.32063997863061255,0.00680547538742138,destabilizing,0.0074265835434863346
+Delta,Zfp36l1,Zyx,0.32063997863061255,0.00680547538742138,destabilizing,0.0074265835434863346
+Delta,Zfp36l1,Igsf5,0.3277894212003852,0.005604233974190537,destabilizing,0.006359089978877426
+Ductal,Celf2,Gpc6,0.21463480875727065,5.245288744809127e-11,destabilizing,2.19276732489765e-10
+Ductal,Celf2,Auts2,-0.230404775603128,1.6773194920845327e-12,stabilizing,9.037197041079853e-12
+Ductal,Celf2,Tenm3,0.21879709819580132,2.168071148932385e-11,destabilizing,9.682309709288403e-11
+Ductal,Cnot1,Nckap5,0.20181610161633118,7.126775622131447e-10,destabilizing,2.3516244782819495e-09
+Ductal,Elavl1,Kcnh7,-0.21255148957655057,8.107745383626329e-11,stabilizing,3.254806089022555e-10
+Ductal,Elavl1,Psmd13,0.247740065236287,2.8135120941313944e-14,destabilizing,1.980142689034247e-13
+Ductal,Elavl1,Naaladl2,0.21322635773289542,7.044430042380988e-11,destabilizing,2.8693795630504247e-10
+Ductal,Elavl1,Gpc6,0.25785453748990256,2.229183222738522e-15,destabilizing,1.8779179876403305e-14
+Ductal,Elavl1,Frmd5,0.26224382882439684,7.16283403655117e-16,destabilizing,6.528747089053198e-15
+Ductal,Elavl1,Exosc5,0.24144802640034302,1.2877217693673464e-13,destabilizing,8.277148020442134e-13
+Ductal,Elavl1,Pdss2,0.2636814011949709,4.91560703669999e-16,destabilizing,4.664644026888176e-15
+Ductal,Elavl1,Tenm3,0.25339216266759407,6.917355546307354e-15,destabilizing,5.416971385558998e-14
+Ductal,Elavl1,Dbndd2,0.2096739501023178,1.468744327020539e-10,destabilizing,5.48068352901624e-10
+Ductal,Elavl1,Slit3,0.22246108885259488,9.814106492710938e-12,destabilizing,4.807615162949146e-11
+Ductal,Elavl1,Nckap5,0.20439299066239203,4.2751536257836333e-10,destabilizing,1.453813710052416e-09
+Ductal,Elavl1,Slc35f1,0.22618558759146684,4.322210706373349e-12,destabilizing,2.194656760496422e-11
+Ductal,Elavl1,Kif24,0.20174625592211803,7.225502236089479e-10,destabilizing,2.3771474812223374e-09
+Ductal,Esrp1,Tenm3,0.20457970432243475,4.118668010446175e-10,destabilizing,1.4092181008049682e-09
+Ductal,Fus,Mecom,0.21750065528598775,2.8603542027571167e-11,destabilizing,1.2522495564826432e-10
+Ductal,Fus,Gpc6,0.29556098435165695,6.361480663432171e-20,destabilizing,9.069187817610993e-19
+Ductal,Fus,Jazf1,0.23899749742697768,2.3018627791141426e-13,destabilizing,1.4543587558948446e-12
+Ductal,Fus,Frmd5,0.23379819760623027,7.727841000807084e-13,destabilizing,4.475707912967436e-12
+Ductal,Fus,Exosc5,0.27989014923102773,5.999329286303003e-18,destabilizing,7.097078900392489e-17
+Ductal,Fus,Adamts6,0.21699478872941325,3.18546795516527e-11,destabilizing,1.3836876430249141e-10
+Ductal,Fus,Pawr,0.2127942308633513,7.708380096079708e-11,destabilizing,3.1169886061238673e-10
+Ductal,Fus,Pdss2,0.24594247028733604,4.3638296115654e-14,destabilizing,2.958889346378491e-13
+Ductal,Fus,Auts2,-0.22206106286256017,1.0708472859439233e-11,stabilizing,5.1773138346506205e-11
+Ductal,Fus,Tenm3,0.30676623634338307,2.063283330445088e-21,destabilizing,3.58495478664834e-20
+Ductal,Fus,Med12l,0.2081590783142378,2.0013044158492314e-10,destabilizing,7.27271408635407e-10
+Ductal,Fus,Hmg20a,0.2546045471558893,5.096423560734905e-15,destabilizing,4.0480164282408673e-14
+Ductal,Fus,AW554918,0.21489255679818098,4.9686124733559125e-11,destabilizing,2.1007973651603705e-10
+Ductal,Fus,Nckap5,0.2804393915323737,5.140312686934711e-18,destabilizing,6.351141897634888e-17
+Ductal,Fus,Kif24,0.2568401226630562,2.8892163869598313e-15,destabilizing,2.397618374850248e-14
+Ductal,Hnrnpa1,Kcnh7,-0.29223588034659553,1.7097853711041026e-19,stabilizing,2.3766016658347025e-18
+Ductal,Hnrnpa1,9030622O22Rik,0.2534893044296748,6.750491938280661e-15,destabilizing,5.3237922236653164e-14
+Ductal,Hnrnpa1,Psmd13,0.2475275462490849,2.9639025224576595e-14,destabilizing,2.0599122531080735e-13
+Ductal,Hnrnpa1,Naaladl2,0.34425247123305086,7.005087359021442e-27,destabilizing,2.22561632663767e-25
+Ductal,Hnrnpa1,Mecom,0.2331694327890349,8.929329251441409e-13,destabilizing,5.1182547049499205e-12
+Ductal,Hnrnpa1,Magi1,0.2524129960222192,8.842640479874336e-15,destabilizing,6.734942612068673e-14
+Ductal,Hnrnpa1,Gpc6,0.30410039454322335,4.7285435451108785e-21,destabilizing,8.08944680332815e-20
+Ductal,Hnrnpa1,Snd1,0.29742427254379783,3.634666068389451e-20,destabilizing,5.536642011026123e-19
+Ductal,Hnrnpa1,Pde1c,-0.2432921351436314,8.282108255295613e-14,stabilizing,5.449529218869067e-13
+Ductal,Hnrnpa1,Tmem164,0.22857669223871424,2.533565347321157e-12,destabilizing,1.3352249602943727e-11
+Ductal,Hnrnpa1,Frmd5,0.25511879185602465,4.4748504157383585e-15,destabilizing,3.632141359343836e-14
+Ductal,Hnrnpa1,Exosc5,0.27855617253314957,8.71922997950346e-18,destabilizing,1.0099774726258174e-16
+Ductal,Hnrnpa1,Adamts6,0.2617273555216599,8.195658575600185e-16,destabilizing,7.409408403306833e-15
+Ductal,Hnrnpa1,Pawr,0.31856164571261464,4.7413095890445955e-23,destabilizing,9.803528541679924e-22
+Ductal,Hnrnpa1,Pmvk,0.21220296268986652,8.716680068801689e-11,destabilizing,3.4372156867047797e-10
+Ductal,Hnrnpa1,Sox5,0.25706790120028217,2.7260379863865875e-15,destabilizing,2.2792137149337482e-14
+Ductal,Hnrnpa1,Pdss2,0.3189704783343815,4.1473538429484046e-23,destabilizing,9.042857790899267e-22
+Ductal,Hnrnpa1,Pdxdc1,0.21164752158247796,9.780520249996997e-11,destabilizing,3.816118778244442e-10
+Ductal,Hnrnpa1,Scmh1,0.21385641260648702,6.175356345032764e-11,destabilizing,2.552786712147373e-10
+Ductal,Hnrnpa1,Mcc,0.21769095784585948,2.7466403031979983e-11,destabilizing,1.2072189791131124e-10
+Ductal,Hnrnpa1,Tenm3,0.2757876683007336,1.8821106721136028e-17,destabilizing,2.0721852152379468e-16
+Ductal,Hnrnpa1,Hmg20a,0.2898162172195931,3.48219411094888e-19,destabilizing,4.7221949407014085e-18
+Ductal,Hnrnpa1,Ssh2,0.24859296927193572,2.281775333386614e-14,destabilizing,1.626496263285843e-13
+Ductal,Hnrnpa1,Slit3,0.2964572191269182,4.862437003883628e-20,destabilizing,7.209373264424793e-19
+Ductal,Hnrnpa1,AW554918,0.20347100637573312,5.136841620446867e-10,destabilizing,1.730959964223308e-09
+Ductal,Hnrnpa1,Nckap5,0.2859960459622398,1.0556346810684998e-18,destabilizing,1.3189502981440131e-17
+Ductal,Hnrnpa1,Slc28a3,0.2076275350626287,2.2295581944994753e-10,destabilizing,8.023523340723031e-10
+Ductal,Hnrnpa1,Kif24,0.24781552481847666,2.761936292283187e-14,destabilizing,1.956224940776372e-13
+Ductal,Hnrnpa2b1,Tenm3,0.2199019197695809,1.7096891250815075e-11,destabilizing,7.823762580619902e-11
+Ductal,Hnrnpc,Kcnh7,-0.23189672077155685,1.1948079763119303e-12,stabilizing,6.7442968002988146e-12
+Ductal,Hnrnpc,Naaladl2,0.22112539528105093,1.3123175556580933e-11,destabilizing,6.157371822328269e-11
+Ductal,Hnrnpc,Gpc6,0.27595268700450737,1.7981810944946393e-17,destabilizing,1.999577377078039e-16
+Ductal,Hnrnpc,Snd1,0.20469016716992708,4.028731748818773e-10,destabilizing,1.3827005261378012e-09
+Ductal,Hnrnpc,Frmd5,0.2011599123610601,8.108532780365515e-10,destabilizing,2.651967191696016e-09
+Ductal,Hnrnpc,Exosc5,0.23061296248354404,1.6000014521247225e-12,destabilizing,8.764539974200451e-12
+Ductal,Hnrnpc,Pawr,0.21258077659454974,8.058510492171483e-11,destabilizing,3.246762198295177e-10
+Ductal,Hnrnpc,Pdss2,0.27160232906844406,5.924204369838593e-17,destabilizing,6.274014532629062e-16
+Ductal,Hnrnpc,Tenm3,0.2315812915089966,1.2838949868355954e-12,destabilizing,7.174327765634081e-12
+Ductal,Hnrnpc,Slit3,0.2769654295950389,1.3581589584458963e-17,destabilizing,1.556982228651378e-16
+Ductal,Hnrnpc,AW554918,0.20454002652425696,4.151447958208197e-10,destabilizing,1.416076726848931e-09
+Ductal,Hnrnpc,Nckap5,0.2226829089814146,9.350100777021005e-12,destabilizing,4.621027584021048e-11
+Ductal,Hnrnpd,Kcnh7,-0.20248901671569985,6.240488823952443e-10,stabilizing,2.0776717282141067e-09
+Ductal,Hnrnpd,Psmd13,0.26869967709085896,1.2969934442488785e-16,destabilizing,1.3111424636406844e-15
+Ductal,Hnrnpd,Ttll3,0.20090131586578344,8.530581531097514e-10,destabilizing,2.7818201356540866e-09
+Ductal,Hnrnpd,Mecom,0.25164537178171714,1.0711881807117877e-14,destabilizing,7.941075046343387e-14
+Ductal,Hnrnpd,Magi1,0.2197445675247371,1.768653070661689e-11,destabilizing,8.060418912195893e-11
+Ductal,Hnrnpd,Gpc6,0.34177504931509733,1.701358976474118e-26,destabilizing,5.1132734644303225e-25
+Ductal,Hnrnpd,Jazf1,0.29561759644756364,6.254586693622865e-20,destabilizing,9.03259792637484e-19
+Ductal,Hnrnpd,Large,0.2387922776327771,2.4158938114325405e-13,destabilizing,1.5092550102881939e-12
+Ductal,Hnrnpd,Frmd5,0.23757048027867986,3.218762313224192e-13,destabilizing,1.977493752654863e-12
+Ductal,Hnrnpd,Exosc5,0.2979094884537522,3.1395504813707847e-20,destabilizing,4.84886129900599e-19
+Ductal,Hnrnpd,Adamts6,0.23864654249311365,2.500217537279412e-13,destabilizing,1.5532077661758135e-12
+Ductal,Hnrnpd,Pawr,0.23189935799391068,1.194089289106762e-12,destabilizing,6.7442968002988146e-12
+Ductal,Hnrnpd,Pdss2,0.24520667346394687,5.217396277587374e-14,destabilizing,3.516208885258885e-13
+Ductal,Hnrnpd,Auts2,-0.26402737082969446,4.488255403425363e-16,stabilizing,4.302534490180175e-15
+Ductal,Hnrnpd,Dnajb11,0.2005331014646779,9.168651035475422e-10,destabilizing,2.9724606272445096e-09
+Ductal,Hnrnpd,Scmh1,0.21477246622387025,5.0957014341521445e-11,destabilizing,2.146371210142873e-10
+Ductal,Hnrnpd,Mcc,0.21320093959729294,7.081888542591163e-11,destabilizing,2.8741095107158295e-10
+Ductal,Hnrnpd,Tenm3,0.3530983235856456,2.7592644014556666e-28,destabilizing,9.297884892177883e-27
+Ductal,Hnrnpd,Med12l,0.20964518612195462,1.4774303771805413e-10,destabilizing,5.494657456270107e-10
+Ductal,Hnrnpd,Hmg20a,0.3240978844677717,7.605069119853125e-24,destabilizing,1.838442795929712e-22
+Ductal,Hnrnpd,Akt3,0.20811638105528937,2.0187640995337973e-10,destabilizing,7.312266054337403e-10
+Ductal,Hnrnpd,AW554918,0.25612852381712775,3.463357782789885e-15,destabilizing,2.8527806329350756e-14
+Ductal,Hnrnpd,Nckap5,0.32023330025998153,2.7394080443479524e-23,destabilizing,6.092443490629846e-22
+Ductal,Hnrnpd,Slc35f1,0.24517971577071135,5.251598837873703e-14,destabilizing,3.51793849862383e-13
+Ductal,Hnrnpd,Fmnl2,0.2871832004951572,7.492449032346673e-19,destabilizing,9.744925799426238e-18
+Ductal,Hnrnpd,Kif24,0.37063862265904346,3.315925691983935e-31,destabilizing,1.4749237477944543e-29
+Ductal,Matr3,Tenm3,0.21251034491065174,8.17741074779482e-11,destabilizing,3.2586596793977374e-10
+Ductal,Matr3,Kif24,0.2086418273253294,1.813863781274586e-10,destabilizing,6.61735750547945e-10
+Ductal,Ptbp1,Naaladl2,0.21678914864494866,3.327714848513957e-11,destabilizing,1.434270895948651e-10
+Ductal,Ptbp1,Gpc6,0.23694601990506456,3.7248602248458383e-13,destabilizing,2.2634123333489464e-12
+Ductal,Ptbp1,Pdss2,0.2199299070806271,1.6994047985557515e-11,destabilizing,7.808835272702462e-11
+Ductal,Ptbp1,Tenm3,0.20608629585843732,3.0445033448071334e-10,destabilizing,1.0713568732359279e-09
+Ductal,Ptbp1,Kif24,0.21018715672088112,1.3218865335319064e-10,destabilizing,4.982840085720271e-10
+Ductal,Pum2,Hmg20a,0.22788160955691056,2.9609773366146274e-12,destabilizing,1.545824787941533e-11
+Ductal,Srsf1,Psmd13,0.22978999717140805,1.927626786689587e-12,destabilizing,1.0305389359609715e-11
+Ductal,Srsf1,Naaladl2,0.20063373581524335,8.98979157230769e-10,destabilizing,2.9229965580134947e-09
+Ductal,Srsf1,Magi1,0.20974006677470683,1.4489670865966824e-10,destabilizing,5.425088889883875e-10
+Ductal,Srsf1,Gpc6,0.23579364064428926,4.871612091386672e-13,destabilizing,2.8815067263946698e-12
+Ductal,Srsf1,Tmem164,0.20672312829022868,2.6775628740141053e-10,destabilizing,9.512619539628386e-10
+Ductal,Srsf1,Jazf1,0.2272280107608219,3.4268566829219187e-12,destabilizing,1.764196588615358e-11
+Ductal,Srsf1,Exosc5,0.20570599184579028,3.286545810511973e-10,destabilizing,1.1492575287073313e-09
+Ductal,Srsf1,Adamts6,0.23539192204368156,5.347636294024391e-13,destabilizing,3.1463341581773136e-12
+Ductal,Srsf1,Pawr,0.2264229023784745,4.100147025941231e-12,destabilizing,2.0914511435076373e-11
+Ductal,Srsf1,Pdss2,0.24629657362625126,4.0034889213390514e-14,destabilizing,2.731214527931917e-13
+Ductal,Srsf1,Auts2,-0.20999958156835344,1.3738204115051953e-10,stabilizing,5.16110911349249e-10
+Ductal,Srsf1,Tenm3,0.3206110387607999,2.418875017058671e-23,destabilizing,5.489365344835189e-22
+Ductal,Srsf1,Hmg20a,0.25234027731126374,9.004998214513847e-15,destabilizing,6.811944227577822e-14
+Ductal,Srsf1,AW554918,0.2217385874374829,1.1487052338917874e-11,destabilizing,5.529697922457435e-11
+Ductal,Srsf1,Nckap5,0.23646553537106674,4.1666361824446005e-13,destabilizing,2.5044861810153493e-12
+Ductal,Srsf1,Kif24,0.2592381456287951,1.5621486325677097e-15,destabilizing,1.3465963406320102e-14
+Ductal,Srsf3,Kcnh7,-0.3401284272448893,3.0550759656421826e-26,stabilizing,8.493111184485269e-25
+Ductal,Srsf3,9030622O22Rik,0.2934757609637273,1.1843844534614354e-19,destabilizing,1.6671335598090077e-18
+Ductal,Srsf3,Psmd13,0.35739000948461647,5.534081798908607e-29,destabilizing,2.0512996534621236e-27
+Ductal,Srsf3,Naaladl2,0.280287197433789,5.365393250761372e-18,destabilizing,6.415394940695319e-17
+Ductal,Srsf3,Traf5,0.2606682578304219,1.0792969737559032e-15,destabilizing,9.535516993668805e-15
+Ductal,Srsf3,Macrod2,0.21363435924473648,6.468980900734941e-11,destabilizing,2.65443053934216e-10
+Ductal,Srsf3,Ttll3,0.29188121901882746,1.8984830876390266e-19,destabilizing,2.6063125845118488e-18
+Ductal,Srsf3,Mecom,0.34188725033761963,1.63462183522222e-26,destabilizing,5.0491652243530795e-25
+Ductal,Srsf3,Sema6a,-0.231166457929113,1.411021123976852e-12,stabilizing,7.76760143496168e-12
+Ductal,Srsf3,Magi1,0.312273579567456,3.619540525395981e-22,destabilizing,7.061279060070756e-21
+Ductal,Srsf3,Plcl1,-0.2635673706079074,5.065046032114419e-16,stabilizing,4.7330514182447344e-15
+Ductal,Srsf3,Gpc6,0.46837352245702746,3.940970306360678e-51,destabilizing,4.382358980673074e-49
+Ductal,Srsf3,Ptprj,0.22370153525661668,7.480604628398115e-12,destabilizing,3.730238720528567e-11
+Ductal,Srsf3,Snd1,0.301332969102094,1.1083963532943228e-20,destabilizing,1.8125540365636573e-19
+Ductal,Srsf3,Pde1c,-0.21125648643630462,1.0604433279075983e-10,stabilizing,4.108756030081008e-10
+Ductal,Srsf3,Ins2,0.2514284159521679,1.1307166295703435e-14,destabilizing,8.326866834981603e-14
+Ductal,Srsf3,Tmem164,0.26664853228498064,2.2435177998615826e-16,destabilizing,2.227492672719714e-15
+Ductal,Srsf3,Jazf1,0.405355030824502,1.5316203515792357e-37,destabilizing,9.462010171978389e-36
+Ductal,Srsf3,Large,0.31085378846521416,5.689294916053927e-22,destabilizing,1.0907751632158563e-20
+Ductal,Srsf3,Ptprd,0.2104775080511765,1.2452531176847384e-10,destabilizing,4.742196804333662e-10
+Ductal,Srsf3,Frmd5,0.36829730217325807,8.336285154619251e-31,destabilizing,3.4333144784950396e-29
+Ductal,Srsf3,Exosc5,0.4134003681477256,4.037378588430594e-39,destabilizing,2.8059781189592625e-37
+Ductal,Srsf3,Adamts6,0.32785440272846855,2.1494611896350714e-24,destabilizing,5.432274642895908e-23
+Ductal,Srsf3,Pawr,0.35930039215763265,2.6853023218608905e-29,destabilizing,1.0664486363961823e-27
+Ductal,Srsf3,Pmvk,0.2177933178908377,2.6873154765288395e-11,destabilizing,1.1858312737698689e-10
+Ductal,Srsf3,Sox5,0.2596424610815882,1.4074185865146429e-15,destabilizing,1.2226948970345959e-14
+Ductal,Srsf3,Rab28,0.21530536049803117,4.5549236708976224e-11,destabilizing,1.9406418092100213e-10
+Ductal,Srsf3,Pdss2,0.41044093604618775,1.5558389530468793e-38,destabilizing,1.0177017151694881e-36
+Ductal,Srsf3,Auts2,-0.39541401068133947,1.1951530115843271e-35,stabilizing,6.3286197565798655e-34
+Ductal,Srsf3,Pdxdc1,0.30991968909307105,7.650572292609169e-22,destabilizing,1.3721671595776445e-20
+Ductal,Srsf3,Dnajb11,0.2428108507578319,9.296515202016063e-14,destabilizing,6.045453160609276e-13
+Ductal,Srsf3,Scmh1,0.29907693356788473,2.2047179160689305e-20,destabilizing,3.453022989674156e-19
+Ductal,Srsf3,Rims1,0.3034733739561732,5.7398592841490675e-21,destabilizing,9.670793218142065e-20
+Ductal,Srsf3,Mcc,0.2584307375948739,1.9228626577728987e-15,destabilizing,1.6322315079721093e-14
+Ductal,Srsf3,Tenm3,0.4895393200739712,2.2572981488893932e-56,destabilizing,3.1376444269562566e-54
+Ductal,Srsf3,Med12l,0.25489720871977384,4.732969531116063e-15,destabilizing,3.7863756248928506e-14
+Ductal,Srsf3,Hmg20a,0.5293001974770891,2.8420777884194083e-67,destabilizing,5.26731750120397e-65
+Ductal,Srsf3,Ssh2,0.25213099667518446,9.488775586951697e-15,destabilizing,7.12940435992587e-14
+Ductal,Srsf3,Akt3,0.26091813856747964,1.0115369506032798e-15,destabilizing,9.07120233121651e-15
+Ductal,Srsf3,Dbndd2,0.2652809804430675,3.2245240530717884e-16,destabilizing,3.1731599531113527e-15
+Ductal,Srsf3,Slit3,0.3004252461959292,1.462777219173397e-20,destabilizing,2.3237260967440254e-19
+Ductal,Srsf3,AW554918,0.395647633766382,1.0806576202303734e-35,destabilizing,6.008456368480876e-34
+Ductal,Srsf3,Nckap5,0.4452968272032899,8.070321840703919e-46,destabilizing,8.158361715329781e-44
+Ductal,Srsf3,Numb,0.21115396807621162,1.0831412598028506e-10,destabilizing,4.182128753127673e-10
+Ductal,Srsf3,Drg1,0.22819124466934507,2.7625049136884057e-12,destabilizing,1.4490120113308995e-11
+Ductal,Srsf3,Slc35f1,0.3408743521976155,2.3444781689212012e-26,destabilizing,6.860683483790462e-25
+Ductal,Srsf3,Fmnl2,0.26825002213737564,1.4631419101644596e-16,destabilizing,1.4657782018944856e-15
+Ductal,Srsf3,Camta1,0.23953241477590534,2.0288678152890786e-13,destabilizing,1.289200577486546e-12
+Ductal,Srsf3,Arf4,0.2206140866235357,1.465988456698932e-11,destabilizing,6.792413182705052e-11
+Ductal,Srsf3,Zc3h12c,0.2347675074954904,6.179429299162552e-13,destabilizing,3.597657267365842e-12
+Ductal,Srsf3,Kif24,0.4444516649490171,1.2410274407470693e-45,destabilizing,1.150018761758951e-43
+Ductal,Tial1,Hmg20a,0.20623236126055464,2.9562368353166284e-10,destabilizing,1.0469220894497104e-09
+Ductal,Tra2b,Psmd13,0.20948741532361875,1.5259722016104903e-10,destabilizing,5.643806367948964e-10
+Ductal,Tra2b,Gpc6,0.263654941181585,4.949892042920906e-16,destabilizing,4.664644026888176e-15
+Ductal,Tra2b,Jazf1,0.22611941386900164,4.386202618872984e-12,destabilizing,2.2170260509939814e-11
+Ductal,Tra2b,Exosc5,0.2475401007393818,2.954802970546367e-14,destabilizing,2.0599122531080735e-13
+Ductal,Tra2b,Pawr,0.20329443744526304,5.3201668194087e-10,destabilizing,1.7873188831366992e-09
+Ductal,Tra2b,Pdss2,0.23823540713015126,2.753969028366529e-13,destabilizing,1.7013408664131e-12
+Ductal,Tra2b,Auts2,-0.22257470843799565,9.573690445432921e-12,stabilizing,4.71059459085018e-11
+Ductal,Tra2b,Tenm3,0.324004116115799,7.846987691901251e-24,destabilizing,1.846344643694334e-22
+Ductal,Tra2b,Hmg20a,0.27174702560567743,5.695837683751136e-17,destabilizing,6.090164908010829e-16
+Ductal,Tra2b,Nckap5,0.23047342812223823,1.6514268575937595e-12,destabilizing,9.001895419824807e-12
+Ductal,Tra2b,Kif24,0.235054977280127,5.781824718120645e-13,destabilizing,3.3838889929211356e-12
+Ductal,Upf1,Pdss2,0.21416867544395046,5.7843583849535315e-11,destabilizing,2.400077061219525e-10
+Ductal,Ybx1,Kcnh7,-0.33293164388418195,3.7871716570060873e-25,stabilizing,9.793802052536672e-24
+Ductal,Ybx1,9030622O22Rik,0.2642760203123116,4.2039082645346154e-16,destabilizing,4.064996513184776e-15
+Ductal,Ybx1,Grip1,0.22009706517231278,1.6392278189583597e-11,destabilizing,7.563574002828613e-11
+Ductal,Ybx1,Psmd13,0.3936600145851391,2.5389967845770227e-35,destabilizing,1.2833474656589316e-33
+Ductal,Ybx1,Naaladl2,0.32634838949173745,3.574883849785715e-24,destabilizing,8.833935202137145e-23
+Ductal,Ybx1,Traf5,0.23140909944651938,1.3352400190592235e-12,destabilizing,7.423934505969283e-12
+Ductal,Ybx1,Macrod2,0.21924196704902177,1.97061906329709e-11,destabilizing,8.907839017830747e-11
+Ductal,Ybx1,Ttll3,0.289174137709074,4.2007371331778753e-19,destabilizing,5.62797553264313e-18
+Ductal,Ybx1,Sntb1,0.2003671033133829,9.47128073838024e-10,destabilizing,3.061646564267101e-09
+Ductal,Ybx1,Mecom,0.33787009582654876,6.779709370822967e-26,destabilizing,1.8387894683793023e-24
+Ductal,Ybx1,Sema6a,-0.2532091747567218,7.24276069769983e-15,stabilizing,5.554448204029112e-14
+Ductal,Ybx1,Magi1,0.30875256102249155,1.1060438880766039e-21,destabilizing,1.9522552437161643e-20
+Ductal,Ybx1,Plcl1,-0.21175563254124216,9.563979628627925e-11,stabilizing,3.7580018894113965e-10
+Ductal,Ybx1,Gpc6,0.4940112630114324,1.5784925637661283e-57,destabilizing,2.5075481870113353e-55
+Ductal,Ybx1,Idh3b,0.21379497296168967,6.255270646821497e-11,destabilizing,2.5762447997279645e-10
+Ductal,Ybx1,Snd1,0.297205462303852,3.882434855763182e-20,destabilizing,5.834145350822511e-19
+Ductal,Ybx1,Atrnl1,0.25547116195213293,4.092603390430578e-15,destabilizing,3.346305125116767e-14
+Ductal,Ybx1,Ins2,0.2879731613750274,5.95873779890198e-19,destabilizing,7.88823384807024e-18
+Ductal,Ybx1,Tmem164,0.30322293964593816,6.201022064929243e-21,destabilizing,1.0291845576419878e-19
+Ductal,Ybx1,Pcdh9,-0.2191111265692306,2.0267909007464952e-11,stabilizing,9.124661868947783e-11
+Ductal,Ybx1,Jazf1,0.369557004142778,5.081274009793937e-31,destabilizing,2.1732218072657145e-29
+Ductal,Ybx1,Large,0.30121588059684895,1.1488422571769049e-20,destabilizing,1.8514675217111857e-19
+Ductal,Ybx1,Ptprd,0.2600268316924742,1.27434159761809e-15,destabilizing,1.11580146185143e-14
+Ductal,Ybx1,Frmd5,0.3805320745575406,6.195186375112889e-33,destabilizing,2.870436353802305e-31
+Ductal,Ybx1,Exosc5,0.4437088694777992,1.8096784844053542e-45,destabilizing,1.5479711343528875e-43
+Ductal,Ybx1,Elovl1,0.2168893443890043,3.25764811948762e-11,destabilizing,1.4095349061751881e-10
+Ductal,Ybx1,Adamts6,0.31042976700325364,6.508904723673354e-22,destabilizing,1.2063170087874617e-20
+Ductal,Ybx1,Pawr,0.35616945508339676,8.761467483502086e-29,destabilizing,3.0446099505169748e-27
+Ductal,Ybx1,Dach1,0.22488906378731077,5.759677336922992e-12,destabilizing,2.8850275669632284e-11
+Ductal,Ybx1,Pmvk,0.2113868494895404,1.032250068370061e-10,destabilizing,4.013503762333943e-10
+Ductal,Ybx1,Sox5,0.31015271963943264,7.106345267688837e-22,destabilizing,1.2954517930606535e-20
+Ductal,Ybx1,Rab28,0.2623172777875293,7.0267601995163e-16,destabilizing,6.457650695753823e-15
+Ductal,Ybx1,Ints6,0.2152666666862556,4.592225339741212e-11,destabilizing,1.949066632745125e-10
+Ductal,Ybx1,Pdss2,0.4861302951955963,1.6707130727453084e-55,destabilizing,2.0642588187697588e-53
+Ductal,Ybx1,Auts2,-0.3569033576030083,6.648226359337862e-29,stabilizing,2.3847831327689362e-27
+Ductal,Ybx1,Pdxdc1,0.2866535382089866,8.73254034361842e-19,destabilizing,1.1161591795521476e-17
+Ductal,Ybx1,Dnajb11,0.23194930536455322,1.1805574864095857e-12,destabilizing,6.732204743012612e-12
+Ductal,Ybx1,Scmh1,0.26953911923906965,1.0350126146578e-16,destabilizing,1.065679655092105e-15
+Ductal,Ybx1,Rims1,0.287162928757987,7.536543334088638e-19,destabilizing,9.744925799426238e-18
+Ductal,Ybx1,Mcc,0.3107932760349043,5.79970139507923e-22,destabilizing,1.0930962629369667e-20
+Ductal,Ybx1,Tenm3,0.5416837221752298,5.6604133708590986e-71,destabilizing,1.2588759336790636e-68
+Ductal,Ybx1,Med12l,0.3364168337272896,1.1284349930821837e-25,destabilizing,2.9876659816842576e-24
+Ductal,Ybx1,Hmg20a,0.41901839903292787,3.0036680871297587e-40,destabilizing,2.226719275258861e-38
+Ductal,Ybx1,Ssh2,0.26488383191768794,3.581335681598145e-16,destabilizing,3.4933730508220503e-15
+Ductal,Ybx1,Akt3,0.26880235804124686,1.2617399099757845e-16,destabilizing,1.2872062200853874e-15
+Ductal,Ybx1,Dbndd2,0.2796477471220894,6.4220620542969355e-18,destabilizing,7.517192636187571e-17
+Ductal,Ybx1,Slit3,0.35748679150641943,5.335643141629618e-29,destabilizing,2.04594316327315e-27
+Ductal,Ybx1,AW554918,0.3455767966344235,4.344861233903871e-27,destabilizing,1.4210252035591484e-25
+Ductal,Ybx1,Nckap5,0.40019771307352636,1.4957907618958591e-36,destabilizing,8.754312248569448e-35
+Ductal,Ybx1,Drg1,0.23677849756876468,3.873405995183789e-13,destabilizing,2.3408844927415073e-12
+Ductal,Ybx1,Dapk1,0.2071170304271257,2.4725779507322635e-10,destabilizing,8.840857495865843e-10
+Ductal,Ybx1,Slc35f1,0.3857720661533456,7.113952478468632e-34,destabilizing,3.4394413721987474e-32
+Ductal,Ybx1,Slc28a3,0.21650597292920842,3.533796144778447e-11,destabilizing,1.517212862159704e-10
+Ductal,Ybx1,Fmnl2,0.27668439783533444,1.4683295519673875e-17,destabilizing,1.6661045528446275e-16
+Ductal,Ybx1,Ube4b,0.2488168414896474,2.159416373557307e-14,destabilizing,1.5492071015456294e-13
+Ductal,Ybx1,Camta1,0.24315588741452854,8.557703955509211e-14,destabilizing,5.597745175603672e-13
+Ductal,Ybx1,Arf4,0.2861536507059988,1.0087608683327321e-18,destabilizing,1.2747069154386344e-17
+Ductal,Ybx1,Zc3h12c,0.2505043527833203,1.4228014023600652e-14,destabilizing,1.0273734801457094e-13
+Ductal,Ybx1,Kif24,0.42686237859322723,7.34339203850234e-42,destabilizing,5.832751390581859e-40
+Ductal,Ybx1,Nol12,0.21816551191291084,2.4819728199868174e-11,destabilizing,1.0995831776196576e-10
+Epsilon,Ago2,Magi1,0.2207276664780355,0.008298784674509117,destabilizing,0.008640682170462675
+Epsilon,Ago2,Vti1a,0.2523385265375758,0.0024490504257726627,destabilizing,0.0030530763155372205
+Epsilon,Alkbh5,Magi1,0.2196701019171264,0.00862174686799142,destabilizing,0.008918495364843217
+Epsilon,Alkbh5,Auts2,0.2851638670934062,0.0005821617835780551,destabilizing,0.0008748160855929693
+Epsilon,Alkbh5,Cacna2d1,0.22324812737329305,0.007571868674935486,destabilizing,0.008088263259053161
+Epsilon,Alkbh5,Usp29,0.24378418500316362,0.003460211398585588,destabilizing,0.004141824623495344
+Epsilon,Celf1,Elovl1,0.24131498258948067,0.0038150200673869564,destabilizing,0.004527537155746313
+Epsilon,Celf2,9030622O22Rik,0.22103823604710868,0.00820599838248372,destabilizing,0.008584261713379018
+Epsilon,Celf2,Mecom,0.2539029663089159,0.002296142328046681,destabilizing,0.002890675239944147
+Epsilon,Celf2,Ptprd,-0.22226750849671337,0.007847687659826652,stabilizing,0.008296345191669063
+Epsilon,Cirbp,2010111I01Rik,0.2275288882310373,0.00646591709350696,destabilizing,0.007168594025902033
+Epsilon,Cirbp,Robo2,0.2636620997159278,0.0015221843557484695,destabilizing,0.00197280769649452
+Epsilon,Cnot1,Fam155a,0.27982074040853083,0.0007445938059022817,destabilizing,0.0010762653718152128
+Epsilon,Cnot1,Ambra1,0.2300027617426908,0.005894526699012823,destabilizing,0.006654531664266253
+Epsilon,Cpeb1,Tmtc2,0.22381563145744837,0.007416204677731611,destabilizing,0.007937266219092928
+Epsilon,Cpeb1,Hs6st3,0.40094451135042747,7.628632849791393e-07,destabilizing,1.774694503968207e-06
+Epsilon,Cpeb1,Pde1c,-0.27219544985263483,0.0010491034899017364,stabilizing,0.0014072413519550433
+Epsilon,Cpeb1,Arhgap26,0.23971152662873646,0.00406260637819317,destabilizing,0.004785612598041107
+Epsilon,Cpeb1,Dnajb11,-0.21627910047213186,0.009733499358972542,stabilizing,0.00979515953590721
+Epsilon,Cpeb4,Frmd5,0.219593418113894,0.00864559123257498,destabilizing,0.008934848931806114
+Epsilon,Cpeb4,Arhgap26,0.2666200317890937,0.001339753973352813,destabilizing,0.0017651734814790616
+Epsilon,Elavl1,Cacna1a,0.22483919914286501,0.007142610180212324,destabilizing,0.007699052555776673
+Epsilon,Elavl1,Mecom,0.3468477291499748,2.3507681153155564e-05,destabilizing,4.814096029891158e-05
+Epsilon,Elavl1,Magi1,0.2901548926232087,0.0004605703867993613,destabilizing,0.0007103387935102494
+Epsilon,Elavl1,Sdk1,-0.2224328977182613,0.007800553440042503,stabilizing,0.008261157547930727
+Epsilon,Elavl1,Fhit,-0.2752693959250524,0.0009147510403955185,stabilizing,0.0012620386562280602
+Epsilon,Elavl1,Ptprj,0.2726754718651454,0.0010269980731531772,destabilizing,0.0013809212301648525
+Epsilon,Elavl1,Zcchc16,-0.29888512131435524,0.0003025610879038786,stabilizing,0.0004933254101893152
+Epsilon,Elavl1,Large,-0.2939700664025708,0.0003839367019339207,stabilizing,0.000605585266029106
+Epsilon,Elavl1,Ptprd,-0.28496913178890265,0.0005874568405079039,stabilizing,0.0008803935399525461
+Epsilon,Elavl1,Sorcs1,-0.22248306807790125,0.007786305090730148,stabilizing,0.008253928752041872
+Epsilon,Elavl1,Dach1,-0.38362163707137936,2.4462918568494333e-06,stabilizing,5.495508171346605e-06
+Epsilon,Elavl1,Egln2,0.3253627303335261,7.784903073403998e-05,destabilizing,0.00014622993610853455
+Epsilon,Elavl1,Megf11,0.30001596962687943,0.00028625398935291804,destabilizing,0.00047087934343261075
+Epsilon,Elavl1,Akt3,0.32142237141167596,9.605296895236971e-05,destabilizing,0.00017742674663627096
+Epsilon,Elavl1,Nlk,0.2773483154218031,0.0008330345493609904,destabilizing,0.001169206758120475
+Epsilon,Elavl1,Nlgn1,-0.28573538709823,0.0005668743069173136,stabilizing,0.0008541520722114536
+Epsilon,Elavl1,Rogdi,-0.24851983622127524,0.002861726998000709,stabilizing,0.003502392076419989
+Epsilon,Elavl1,Arhgef38,0.24975434343454514,0.002721917452666568,destabilizing,0.0033556232897618892
+Epsilon,Elavl1,Zc3h12c,0.21642210203194312,0.009684178619342666,destabilizing,0.00976319730254673
+Epsilon,Elavl1,Ankrd28,-0.22975441180699802,0.00594978187824987,stabilizing,0.006669513557070419
+Epsilon,Elavl2,Pkhd1,0.24223628967189378,0.0036789790844543153,destabilizing,0.0043754275314579665
+Epsilon,Elavl2,Camkmt,0.24291821912198794,0.003581111809789623,destabilizing,0.004273696495892317
+Epsilon,Elavl2,Gabbr2,0.3155369456322957,0.00013076598418303525,destabilizing,0.00023491401358890986
+Epsilon,Elavl2,Ankrd28,0.2238499197649697,0.007406891158513169,destabilizing,0.0079349354222222
+Epsilon,Elavl4,Nr6a1,0.22903807161792633,0.006111755395106568,destabilizing,0.006823566264416168
+Epsilon,Esrp1,Traf5,-0.2429125822415292,0.003581911091880971,stabilizing,0.004273696495892317
+Epsilon,Fto,Pcdh9,0.235238081054251,0.004831377360065564,destabilizing,0.005608028835483202
+Epsilon,Fto,Med21,0.22569820025129927,0.0069199600575720905,destabilizing,0.007507312764897721
+Epsilon,Fto,Mcc,0.21727457224568422,0.00939471150203358,destabilizing,0.00955983420824976
+Epsilon,Fus,Large,-0.2487048709886101,0.0028403666459870924,stabilizing,0.0034823458768882543
+Epsilon,Fus,Smim10l1,-0.21620920884066744,0.00975768521010398,stabilizing,0.009801757862362806
+Epsilon,Hnrnpa1,Ptprn2,0.3180472964222319,0.00011473180575508238,destabilizing,0.00021018413179514265
+Epsilon,Hnrnpa1,Kalrn,0.2319096755201806,0.005485278428019846,destabilizing,0.006256030371239045
+Epsilon,Hnrnpa1,Cacnb2,0.26609835207579075,0.0013704036656903373,destabilizing,0.0018012870877631855
+Epsilon,Hnrnpa1,Tmtc2,-0.3932785504991727,1.2880839674827262e-06,stabilizing,2.9411691413568614e-06
+Epsilon,Hnrnpa1,Pde4d,-0.28401625994482355,0.000614011709524741,stabilizing,0.0009164845919349153
+Epsilon,Hnrnpa1,Pkhd1,-0.2548526457733149,0.002207593702293878,stabilizing,0.0027895956783531733
+Epsilon,Hnrnpa1,Adgrb3,-0.3010575126249011,0.00027195903533719747,stabilizing,0.00045002745133179104
+Epsilon,Hnrnpa1,Arl15,-0.21726925916816806,0.009396491717281463,stabilizing,0.00955983420824976
+Epsilon,Hnrnpa1,Rora,-0.5592137736963058,4.714081317846473e-13,stabilizing,2.803239799703357e-12
+Epsilon,Hnrnpa1,Naaladl2,-0.3603087675073373,1.0603395951547394e-05,stabilizing,2.2416304749278903e-05
+Epsilon,Hnrnpa1,Wwox,0.23769015723797304,0.004395231698848872,destabilizing,0.00514473436749468
+Epsilon,Hnrnpa1,Slc8a1,0.2583224364662836,0.001909765097919262,destabilizing,0.002429815547924736
+Epsilon,Hnrnpa1,Macrod2,-0.3261621702989288,7.457360089429127e-05,stabilizing,0.00014055227829568116
+Epsilon,Hnrnpa1,Mbd5,-0.26359820615115487,0.0015263635081431016,stabilizing,0.001975921095524015
+Epsilon,Hnrnpa1,Nr6a1,0.24534118158994878,0.0032520429444639486,destabilizing,0.003930730167656425
+Epsilon,Hnrnpa1,Sntb1,-0.3154077139934958,0.00013164544422878804,stabilizing,0.00023611247416518112
+Epsilon,Hnrnpa1,Cacna1c,0.286310555968548,0.0005518633445875642,destabilizing,0.0008337935314964286
+Epsilon,Hnrnpa1,Mecom,0.32644455204954315,7.344778109424983e-05,destabilizing,0.0001386654203341355
+Epsilon,Hnrnpa1,Tecpr2,-0.35090004112194795,1.8568214849790288e-05,stabilizing,3.852211737493806e-05
+Epsilon,Hnrnpa1,Magi1,0.3334069969720886,5.0237532042390166e-05,destabilizing,9.732427810302763e-05
+Epsilon,Hnrnpa1,Sdk1,-0.2866091277395347,0.0005442163436423308,stabilizing,0.0008244803462265284
+Epsilon,Hnrnpa1,Rrm2b,0.4414029542513539,3.8309619542181374e-08,destabilizing,1.0623515444116132e-07
+Epsilon,Hnrnpa1,Plcl1,0.3993430134704762,8.520113308193273e-07,destabilizing,1.9697226608546613e-06
+Epsilon,Hnrnpa1,Idh3b,0.35917896102659924,1.1351999884933905e-05,destabilizing,2.3907999757663832e-05
+Epsilon,Hnrnpa1,Ptprj,0.5449247813021348,2.3666554808485213e-12,destabilizing,1.2591966003366295e-11
+Epsilon,Hnrnpa1,Nedd8,0.3743205316170612,4.451997810811027e-06,destabilizing,9.842189991295947e-06
+Epsilon,Hnrnpa1,Rims2,-0.24633803025962123,0.0031247623489775935,stabilizing,0.0037975253902328785
+Epsilon,Hnrnpa1,Glis3,0.327300258641047,7.013252465907156e-05,destabilizing,0.00013308424474554192
+Epsilon,Hnrnpa1,Maml3,0.348042303677635,2.193602807335459e-05,destabilizing,4.5088471751516275e-05
+Epsilon,Hnrnpa1,Dip2c,-0.3400153254603866,3.4734678160462014e-05,stabilizing,6.897314663291743e-05
+Epsilon,Hnrnpa1,Pard3b,-0.24008339652378208,0.004003935705418337,stabilizing,0.004721502125583447
+Epsilon,Hnrnpa1,Med21,-0.23866656157265573,0.004231626960701533,stabilizing,0.004968922048891346
+Epsilon,Hnrnpa1,Chrm3,-0.2798012559465216,0.0007452556981094549,stabilizing,0.0010762653718152128
+Epsilon,Hnrnpa1,Rapgef4,0.4964888061210185,3.30426226530608e-10,destabilizing,1.1518306078433732e-09
+Epsilon,Hnrnpa1,Zcchc16,-0.45983890238531644,8.5649201566972e-09,stabilizing,2.519627305356425e-08
+Epsilon,Hnrnpa1,Ctnna2,-0.22934505517712694,0.006041867592353873,stabilizing,0.0067591114312852175
+Epsilon,Hnrnpa1,Large,-0.4730169890690063,2.7764642566529875e-09,stabilizing,8.648258412879894e-09
+Epsilon,Hnrnpa1,Ptprd,-0.43085587843322226,8.679917559369946e-08,stabilizing,2.2926528090307317e-07
+Epsilon,Hnrnpa1,Frmd5,-0.2986898050017037,0.00030546326430943595,stabilizing,0.0004966010963627088
+Epsilon,Hnrnpa1,Chchd3,0.2240149571230826,0.007362208127625906,destabilizing,0.00789467255344263
+Epsilon,Hnrnpa1,Phactr1,-0.2317984790883375,0.005508427110877311,stabilizing,0.006275994823048739
+Epsilon,Hnrnpa1,Smim10l1,-0.4223327882466964,1.647641058894778e-07,stabilizing,4.202240498832553e-07
+Epsilon,Hnrnpa1,Sik3,0.2743960011168346,0.0009512236728390466,destabilizing,0.0012994603491363879
+Epsilon,Hnrnpa1,Sorcs1,-0.25061481069413133,0.00262815137082964,stabilizing,0.0032508390704811567
+Epsilon,Hnrnpa1,Exoc6b,-0.22499142424781754,0.007102696160145556,stabilizing,0.007675605568592671
+Epsilon,Hnrnpa1,Dach1,-0.34013682433567766,3.449709749241542e-05,stabilizing,6.862392202426824e-05
+Epsilon,Hnrnpa1,Ptprg,-0.34366758228738936,2.8224094164246702e-05,stabilizing,5.675441719826823e-05
+Epsilon,Hnrnpa1,Pmvk,0.3320702743227365,5.407616449949352e-05,destabilizing,0.00010385612249298237
+Epsilon,Hnrnpa1,Sox5,-0.4107216058337983,3.8363785056125467e-07,stabilizing,9.253910842171696e-07
+Epsilon,Hnrnpa1,Magi3,-0.4818433625097972,1.2706875915051774e-09,stabilizing,4.060358051016544e-09
+Epsilon,Hnrnpa1,Egln2,0.42985721737332083,9.365421495094525e-08,destabilizing,2.4620209698688206e-07
+Epsilon,Hnrnpa1,Tmem178b,-0.46110660109579255,7.701150443824802e-09,stabilizing,2.2715329691069443e-08
+Epsilon,Hnrnpa1,Dnajb11,0.40545024892970005,5.572527695864482e-07,destabilizing,1.3297533900861166e-06
+Epsilon,Hnrnpa1,Unc5c,-0.2166179006187045,0.0096170058500346,stabilizing,0.009732954111727176
+Epsilon,Hnrnpa1,Farp1,-0.3046172891536813,0.00022794701751784543,stabilizing,0.00038231837628935767
+Epsilon,Hnrnpa1,Pnp,-0.25933279493262773,0.0018301808935882945,stabilizing,0.0023339004055850728
+Epsilon,Hnrnpa1,Shank2,-0.2622728751440094,0.001615442444757247,stabilizing,0.0020815434514137414
+Epsilon,Hnrnpa1,Megf11,0.2818022658311845,0.0006800328198022142,destabilizing,0.000996306318340003
+Epsilon,Hnrnpa1,Agbl4,-0.3359468276642777,4.363775072768849e-05,stabilizing,8.543165283308028e-05
+Epsilon,Hnrnpa1,Chst9,-0.3120131113366563,0.0001568190745233288,stabilizing,0.0002750517521607912
+Epsilon,Hnrnpa1,Bcas3,-0.3603167260764551,1.0598291964061728e-05,stabilizing,2.2416304749278903e-05
+Epsilon,Hnrnpa1,Hmg20a,0.3037949500626913,0.00023748277713551866,destabilizing,0.00039711405740555905
+Epsilon,Hnrnpa1,Hivep2,-0.2993984718749515,0.00029505463149289356,stabilizing,0.0004839244103541263
+Epsilon,Hnrnpa1,Asic2,0.26499585414220544,0.0014372923822286111,destabilizing,0.001871509518780112
+Epsilon,Hnrnpa1,Akt3,0.33962344832577396,3.551147674590363e-05,destabilizing,7.03899503412564e-05
+Epsilon,Hnrnpa1,AW554918,-0.3444089262996758,2.7051102119374066e-05,stabilizing,5.4792031979497196e-05
+Epsilon,Hnrnpa1,Nckap5,0.24768302779714607,0.0029601507610584003,destabilizing,0.0036053533913438566
+Epsilon,Hnrnpa1,Numb,-0.27876819661138824,0.0007811329441243122,stabilizing,0.0011121892879209158
+Epsilon,Hnrnpa1,Drg1,0.3134346164026252,0.00014577639894008864,destabilizing,0.00025895104731849607
+Epsilon,Hnrnpa1,Nlgn1,-0.4395444153240471,4.43383124459518e-08,stabilizing,1.2204010752450098e-07
+Epsilon,Hnrnpa1,1110051M20Rik,-0.254535052717352,0.0022368556047812687,stabilizing,0.002823363714547981
+Epsilon,Hnrnpa1,Rogdi,-0.2711630278527396,0.0010981302039819694,stabilizing,0.0014659313167202281
+Epsilon,Hnrnpa1,Arhgef38,0.2248294855003775,0.0071451638826992145,destabilizing,0.007699052555776673
+Epsilon,Hnrnpa1,Plekhg1,0.22610425578144686,0.006816875177131079,destabilizing,0.007431730585264471
+Epsilon,Hnrnpa1,Camta1,-0.3998099945845253,8.25040633192942e-07,stabilizing,1.911344133563649e-06
+Epsilon,Hnrnpa1,Zc3h12c,0.340898443699415,3.30422458245371e-05,destabilizing,6.584762967183737e-05
+Epsilon,Hnrnpa1,Kcnip4,-0.3512621716724875,1.817804164215556e-05,stabilizing,3.778314449734015e-05
+Epsilon,Hnrnpa1,Ankrd28,-0.2214007836945689,0.008098845782758128,stabilizing,0.008480147373283464
+Epsilon,Hnrnpa2b1,Ptprd,0.27101858926867295,0.0011051538509387225,destabilizing,0.0014735384679182967
+Epsilon,Hnrnpa2b1,Adamts6,-0.21647942935236508,0.009664468589099905,stabilizing,0.009752167941088108
+Epsilon,Hnrnpa2b1,Megf11,-0.23223222871832802,0.005418620479550807,stabilizing,0.006192709119486636
+Epsilon,Hnrnpa2b1,Chst9,0.2681657714285166,0.001252575176469855,destabilizing,0.0016561992820861816
+Epsilon,Hnrnpc,Naaladl2,0.21587422830092906,0.009874341521706196,destabilizing,0.009888507580853093
+Epsilon,Hnrnpc,Sntb1,0.2680866217128436,0.0012569101531042571,destabilizing,0.001659957351843152
+Epsilon,Hnrnpc,Tecpr2,0.2797409961135674,0.0007473061625949129,destabilizing,0.0010772242638442437
+Epsilon,Hnrnpc,Gpc6,0.22285964207538916,0.007680092642481441,destabilizing,0.008172500496114222
+Epsilon,Hnrnpc,Idh3b,-0.25937363504989236,0.0018270283167014598,stabilizing,0.0023325550954902676
+Epsilon,Hnrnpc,Rapgef4,-0.24694674880348613,0.0030492662317483745,stabilizing,0.003709829376043974
+Epsilon,Hnrnpc,Ambra1,0.26342299725847607,0.001537877273129495,destabilizing,0.001986201542067362
+Epsilon,Hnrnpc,Pdss2,-0.25387920624202,0.0022983984222937352,stabilizing,0.002890675239944147
+Epsilon,Hnrnpc,Plcb1,0.2183900916633259,0.009027469495129746,destabilizing,0.009245422319607328
+Epsilon,Igf2bp1,Pkhd1,0.25973975075701555,0.0017989863942205738,destabilizing,0.0023020401270118273
+Epsilon,Igf2bp1,Snd1,0.2356481488089689,0.004755844884279996,destabilizing,0.005531903254518154
+Epsilon,Igf2bp1,Exosc5,0.22217897375413834,0.00787302271608314,destabilizing,0.008304727562078753
+Epsilon,Igf2bp1,Phactr1,0.25324983898526476,0.0023588949070852687,destabilizing,0.002953931460223895
+Epsilon,Igf2bp1,Magi3,0.25115571769473033,0.0025707134316971204,destabilizing,0.0031868822029511683
+Epsilon,Igf2bp1,Plcb1,0.2839194262508836,0.000616771244053105,destabilizing,0.0009192490387986123
+Epsilon,Igf2bp1,Eda,0.22629718357758205,0.006768376904974357,destabilizing,0.007422519840563595
+Epsilon,Igf2bp1,Tbc1d5,0.26601256686597047,0.0013755045258082826,destabilizing,0.0018058571814625857
+Epsilon,Igf2bp1,Camta1,0.24878369446783086,0.0028313111092165733,destabilizing,0.0034763818013189614
+Epsilon,Igf2bp1,Gm14325,0.22629718357758205,0.006768376904974357,destabilizing,0.007422519840563595
+Epsilon,Igf2bp3,Pan3,0.24495972046587317,0.003301972269822842,destabilizing,0.003982422086814534
+Epsilon,Khdrbs1,Ins2,0.26470079285730974,0.0014556918665943762,destabilizing,0.001893250708366019
+Epsilon,Matr3,Ptprn2,-0.3091139792648196,0.0001817949686819908,stabilizing,0.00031323304965760317
+Epsilon,Matr3,Pkhd1,0.21587023888595536,0.009875738202448865,destabilizing,0.009888507580853093
+Epsilon,Matr3,Rora,0.22894969030126533,0.00613200934792556,destabilizing,0.006839312331888889
+Epsilon,Matr3,Naaladl2,0.30166873300606156,0.0002638813036977778,destabilizing,0.000438618848597801
+Epsilon,Matr3,Macrod2,0.2615574022380034,0.0016654745813116508,destabilizing,0.0021410494039520874
+Epsilon,Matr3,Tecpr2,0.2718369010452504,0.001065898155162717,destabilizing,0.001424613880457862
+Epsilon,Matr3,Ptprj,-0.27674059870878076,0.0008562007600840467,stabilizing,0.001193101811044436
+Epsilon,Matr3,Snd1,0.3239379109267944,8.402265009547133e-05,destabilizing,0.00015676709212443643
+Epsilon,Matr3,Dip2c,0.21860298832933123,0.008958840555560297,destabilizing,0.009198735639688873
+Epsilon,Matr3,Tmem164,-0.2688511712830255,0.0012156035047480515,stabilizing,0.0016130681351787988
+Epsilon,Matr3,Rapgef4,-0.22822621486567185,0.006300065921654655,stabilizing,0.007005673304879977
+Epsilon,Matr3,Zcchc16,0.22715430357512928,0.006556602402885702,destabilizing,0.0072474571292334995
+Epsilon,Matr3,Magi3,0.23098928350010034,0.005679527428043184,destabilizing,0.006431399694484747
+Epsilon,Matr3,Rapgef2,0.22022539126988158,0.00845081127155139,destabilizing,0.008757970301924647
+Epsilon,Matr3,Plcb1,0.29179922399624575,0.0004259572172712769,destabilizing,0.0006643259826166338
+Epsilon,Matr3,Shank2,0.25103480123431116,0.0025834538714018694,destabilizing,0.0031991099164798203
+Epsilon,Matr3,Megf11,-0.2444003507392613,0.0033764374646884443,stabilizing,0.004054641966234935
+Epsilon,Matr3,Chst9,0.24999046419160711,0.0026958906600088118,destabilizing,0.0033272257646279678
+Epsilon,Matr3,Hmg20a,-0.2907202633438798,0.0004483867502891967,stabilizing,0.000693471580419453
+Epsilon,Matr3,Ssh2,-0.25487323938031625,0.0022057083153066,stabilizing,0.0027895956783531733
+Epsilon,Matr3,Arhgef38,-0.22457488413541313,0.007212387981344042,stabilizing,0.007756455933515063
+Epsilon,Matr3,Ankrd28,0.21606413801690394,0.009808055843657081,destabilizing,0.009843463987496998
+Epsilon,Mbnl1,Psmd13,-0.22983905618145078,0.005930897770082359,stabilizing,0.006669513557070419
+Epsilon,Mbnl1,Mcc,0.30596898744251144,0.00021304177579175085,destabilizing,0.00036058212280125866
+Epsilon,Mbnl1,Dbndd2,0.30596898744251144,0.00021304177579175085,destabilizing,0.00036058212280125866
+Epsilon,Mbnl1,Igsf5,0.22154637519401707,0.008056165449008848,destabilizing,0.008443408086048858
+Epsilon,Mettl3,Lrch1,-0.30147289808524286,0.00026644485775852595,stabilizing,0.00044221892810071767
+Epsilon,Mettl3,Shank2,0.2191459987025561,0.008785879640376483,destabilizing,0.009054585875902363
+Epsilon,Msi1,Arl15,-0.24831753611827784,0.0028852463691304764,stabilizing,0.0035257076510693294
+Epsilon,Msi1,Btbd9,-0.28453357791265343,0.0005994609226327142,stabilizing,0.000897174355272649
+Epsilon,Msi1,Rapgef4,0.24243158715664437,0.003650707988482448,destabilizing,0.004351111771910485
+Epsilon,Msi1,Vti1a,-0.2203010741299355,0.008427747390853486,stabilizing,0.008750378243351144
+Epsilon,Msi1,Large,-0.2288797117031867,0.006148088424869062,stabilizing,0.00685037507861162
+Epsilon,Msi1,Frmd5,-0.27502299160149984,0.0009249087625489439,stabilizing,0.0012728942375673585
+Epsilon,Msi1,Cdk14,-0.24080845264484135,0.0038917257666550168,stabilizing,0.004608731685325217
+Epsilon,Msi1,Magi3,-0.23228654629318146,0.00540746680811469,stabilizing,0.006186320052081827
+Epsilon,Msi1,Pdss2,0.2536890960978812,0.0023165224420083745,destabilizing,0.0029041408743103857
+Epsilon,Msi1,Farp1,-0.2645319086102092,0.0014663195594380217,stabilizing,0.001904845035157804
+Epsilon,Msi1,Camta1,-0.2169444672253492,0.009505884331467986,stabilizing,0.00965346427086064
+Epsilon,Msi1,Dennd4c,-0.2969425143744068,0.0003325971897227794,stabilizing,0.0005360117028575807
+Epsilon,Msi1,Nol12,-0.22616192666455678,0.006802345578871015,stabilizing,0.0074265835434863346
+Epsilon,Msi2,Adgrb3,0.26088254838608976,0.0017139545336981004,destabilizing,0.00220082845435599
+Epsilon,Msi2,Rora,0.25305052415864293,0.0023783521241673394,destabilizing,0.0029716040023304285
+Epsilon,Msi2,Farp1,0.21680602923410225,0.009552851858845232,destabilizing,0.009692309550215236
+Epsilon,Nova1,Ttll3,0.2257990820134539,0.006894220815088768,destabilizing,0.007501343978844139
+Epsilon,Nova1,2010111I01Rik,0.5649547286720796,2.411706079348181e-13,destabilizing,1.5092550102881939e-12
+Epsilon,Nova1,Robo2,0.4910051790485241,5.512379479842831e-10,destabilizing,1.8463150546943459e-09
+Epsilon,Nova1,Unc5c,0.22259625815510703,0.007754243879216827,destabilizing,0.008227785490161366
+Epsilon,Nova1,Eda,0.7096098218674685,4.848867534104279e-23,destabilizing,9.803528541679924e-22
+Epsilon,Nova1,Trpm3,0.7096098218674685,4.848867534104279e-23,destabilizing,9.803528541679924e-22
+Epsilon,Nova1,Slc35f1,1.0,0.0,destabilizing,0.0
+Epsilon,Nova1,Fmnl2,0.29173512770620236,0.00042726014999062506,destabilizing,0.0006654247714139706
+Epsilon,Nova1,Gm14325,0.7096098218674685,4.848867534104279e-23,destabilizing,9.803528541679924e-22
+Epsilon,Nova1,Abtb2,1.0,0.0,destabilizing,0.0
+Epsilon,Ptbp1,Smim10l1,-0.22213196597449766,0.007886503871902125,stabilizing,0.008304727562078753
+Epsilon,Ptbp1,Map7,0.25033998168092325,0.00265777735723765,destabilizing,0.003283831579164741
+Epsilon,Ptbp1,Rapgef2,0.23201300682818582,0.005463844994380371,destabilizing,0.006237983196869582
+Epsilon,Ptbp1,Dnajb11,0.22185114069877315,0.007967467435171387,destabilizing,0.00836621698575126
+Epsilon,Ptbp2,Rora,-0.2375488483326528,0.004419373191243718,stabilizing,0.005167553090076776
+Epsilon,Ptbp2,Idh3b,0.2538562261840058,0.002300582362725333,destabilizing,0.002890675239944147
+Epsilon,Ptbp2,Map7,-0.22976555593468162,0.005947292570213226,stabilizing,0.006669513557070419
+Epsilon,Ptbp2,Pmvk,0.2231411967766452,0.007601521593465988,destabilizing,0.00810224543578546
+Epsilon,Ptbp2,Atxn1,-0.23536869008588346,0.0048072041001111,stabilizing,0.005585800375468697
+Epsilon,Pum2,Wwox,-0.26588103655079537,0.001383359074655471,stabilizing,0.0018090681254488167
+Epsilon,Pum2,Ins2,-0.224453860336457,0.0072445391493396035,stabilizing,0.007783504863831536
+Epsilon,Pum2,Pcdh9,0.2345894694731107,0.004953042232540634,destabilizing,0.005725346114953415
+Epsilon,Rbfox1,Airn,0.33825769684671947,3.834817015524491e-05,destabilizing,7.560844895856798e-05
+Epsilon,Rbfox1,Grip1,0.39212851067494464,1.3918213369567316e-06,destabilizing,3.1585822993793585e-06
+Epsilon,Rbfox1,Nos1ap,0.22073410626348405,0.00829685132529722,destabilizing,0.008640682170462675
+Epsilon,Rbfox1,Chrm3,0.2628814721134136,0.0015739653284544306,destabilizing,0.0020304517926233493
+Epsilon,Rbfox1,Pawr,0.23167959913605354,0.005533271765311067,destabilizing,0.006297848723670324
+Epsilon,Rbfox1,Igsf5,0.2697953579320251,0.001166304471035067,destabilizing,0.0015494988910286674
+Epsilon,Rbfox3,Ptprj,0.276227557751656,0.0008762163798118415,destabilizing,0.0012118813611327957
+Epsilon,Rbfox3,Rapgef4,0.24475884935007655,0.003328540902616525,destabilizing,0.004009796286580171
+Epsilon,Rbfox3,Zcchc16,-0.2176340833765329,0.00927494192835957,stabilizing,0.009463668310081394
+Epsilon,Rbfox3,Sorcs1,-0.22322198041140281,0.00757910999634298,stabilizing,0.008088263259053161
+Epsilon,Rbfox3,Egln2,0.2251755668096531,0.007054678091816011,destabilizing,0.007638560893962419
+Epsilon,Rbfox3,Kcnq1,0.21914870664910288,0.0087850245471847,destabilizing,0.009054585875902363
+Epsilon,Rbfox3,Cacna2d1,0.24067501224298196,0.003912162416530775,destabilizing,0.00461817898851616
+Epsilon,Rbfox3,Shank2,-0.2406853613706676,0.003910573985884892,stabilizing,0.00461817898851616
+Epsilon,Rbfox3,Megf11,0.3422491777068529,3.0602857091496005e-05,destabilizing,6.10958295973852e-05
+Epsilon,Rbfox3,Slit3,-0.2719626976788323,0.0010599779409906358,stabilizing,0.0014201150245561288
+Epsilon,Rbfox3,Nckap5,0.3354507815526327,4.485909554645253e-05,destabilizing,8.751458639939511e-05
+Epsilon,Srsf3,Ptprn2,0.26568564850389825,0.0013951025478491385,destabilizing,0.0018187034386966494
+Epsilon,Srsf3,Cacnb2,0.2976587846780976,0.0003212150063299003,destabilizing,0.0005199288020943946
+Epsilon,Srsf3,Tmtc2,-0.3090952068702697,0.00018196812057447092,stabilizing,0.00031323304965760317
+Epsilon,Srsf3,Rora,-0.33704246300699114,4.104981121930067e-05,stabilizing,8.050686080399002e-05
+Epsilon,Srsf3,Macrod2,-0.2222639636300473,0.007848700666938718,stabilizing,0.008296345191669063
+Epsilon,Srsf3,Nr6a1,0.29855627061946116,0.00030746224982933126,destabilizing,0.0004991211997229436
+Epsilon,Srsf3,Pbx1,0.2478782803846159,0.0029369161359179387,destabilizing,0.003581070157477642
+Epsilon,Srsf3,Sntb1,-0.2605386538645128,0.0017391497793628667,stabilizing,0.0022280352012114145
+Epsilon,Srsf3,Cacna1c,0.21875277598855147,0.008910831934433795,destabilizing,0.00916636920544901
+Epsilon,Srsf3,Mecom,0.3627660535400528,9.133085990198937e-06,destabilizing,1.9606161430697333e-05
+Epsilon,Srsf3,Tecpr2,-0.22761694473949148,0.006444761717784194,stabilizing,0.007152270489197629
+Epsilon,Srsf3,Magi1,0.2455649306316083,0.0032230741087664596,destabilizing,0.0038999547431428764
+Epsilon,Srsf3,Rrm2b,0.3426800303637432,2.986106375094835e-05,destabilizing,5.982973493883705e-05
+Epsilon,Srsf3,Fhit,-0.241188597993442,0.0038340306382620183,stabilizing,0.004545247409112329
+Epsilon,Srsf3,Plcl1,0.318178516920298,0.00011394635015367812,destabilizing,0.0002090896722291915
+Epsilon,Srsf3,Gpc6,-0.2220479380801192,0.00791065283090573,stabilizing,0.008321687541696016
+Epsilon,Srsf3,Ptprj,0.4875912960429761,7.546416214886386e-10,destabilizing,2.4754026050010798e-09
+Epsilon,Srsf3,Nedd8,0.2991574066057282,0.00029855784961428644,destabilizing,0.00048822989525159786
+Epsilon,Srsf3,Rims2,-0.21661157490818506,0.009619169576248351,stabilizing,0.009732954111727176
+Epsilon,Srsf3,Maml3,0.22213918473721667,0.007884432306052295,destabilizing,0.008304727562078753
+Epsilon,Srsf3,Dip2c,-0.2808581070810805,0.000710124139912825,stabilizing,0.00103493845816915
+Epsilon,Srsf3,Chrm3,-0.2779385539512687,0.0008110865455801673,stabilizing,0.0011471531454207964
+Epsilon,Srsf3,Lcorl,-0.3050293859452693,0.00022330325578530667,stabilizing,0.0003768030659078316
+Epsilon,Srsf3,Rapgef4,0.3650428930853676,7.944610765008382e-06,destabilizing,1.7187562588889727e-05
+Epsilon,Srsf3,Zcchc16,-0.31666576494823484,0.0001233135643885728,stabilizing,0.00022442665073664966
+Epsilon,Srsf3,Cadps,0.32497798173999953,7.947292020934487e-05,destabilizing,0.00014902847769442072
+Epsilon,Srsf3,Large,-0.371736799690694,5.240613150810315e-06,stabilizing,1.1494204780475484e-05
+Epsilon,Srsf3,Ptprd,-0.3100474553656981,0.0001733755569553062,stabilizing,0.0003008731494891529
+Epsilon,Srsf3,Smim10l1,-0.27475783979716717,0.0009359547282502452,stabilizing,0.0012817508101160993
+Epsilon,Srsf3,Sorcs1,-0.31606677258364985,0.0001272172934223852,stabilizing,0.00022965199721703303
+Epsilon,Srsf3,Dach1,-0.2809259384673436,0.0007079221431363567,stabilizing,0.0010330832325034496
+Epsilon,Srsf3,Pmvk,0.2455808803157723,0.0032210180083802067,destabilizing,0.0038999547431428764
+Epsilon,Srsf3,Sox5,-0.22548352432855576,0.006975017432071818,stabilizing,0.007559668016046648
+Epsilon,Srsf3,Egln2,0.33479990474399995,4.651034305058168e-05,destabilizing,9.041870886756438e-05
+Epsilon,Srsf3,Tmem178b,-0.22574468293578312,0.006908089751761219,stabilizing,0.007501753714803198
+Epsilon,Srsf3,Dnajb11,0.3120334000194961,0.00015665613084738365,destabilizing,0.0002750517521607912
+Epsilon,Srsf3,Farp1,-0.28357683706446923,0.0006266261290765484,stabilizing,0.0009290776740441624
+Epsilon,Srsf3,Pnp,-0.2926115809624442,0.00040975876742699216,stabilizing,0.0006426681937641964
+Epsilon,Srsf3,Megf11,0.34541616129919284,2.5530733454587536e-05,destabilizing,5.1996658610808314e-05
+Epsilon,Srsf3,Bcas3,-0.2450834165253674,0.0032857065717360884,stabilizing,0.003967107174560836
+Epsilon,Srsf3,Hmg20a,0.24850870544912432,0.002863016544483606,destabilizing,0.003502392076419989
+Epsilon,Srsf3,Akt3,0.40473417860072064,5.859528253364821e-07,destabilizing,1.3922639781499318e-06
+Epsilon,Srsf3,AW554918,-0.27648016076540105,0.0008663083856294198,stabilizing,0.0012019130415949577
+Epsilon,Srsf3,Numb,-0.3047378206025075,0.00022657960108237287,stabilizing,0.000381458986449281
+Epsilon,Srsf3,Nlgn1,-0.31095962282791023,0.000165500009956262,stabilizing,0.0002884576976040178
+Epsilon,Srsf3,Zyx,0.29716840402426814,0.00032896791726850274,destabilizing,0.0005309322554464079
+Epsilon,Srsf3,Arhgef38,0.24434352790074595,0.003384085912689706,destabilizing,0.004059442863981611
+Epsilon,Srsf3,Camta1,-0.3258617965714576,7.578885856371337e-05,stabilizing,0.00014260103337199537
+Epsilon,Srsf3,Igsf5,-0.22060681789471115,0.008335139798370677,stabilizing,0.008670416703263042
+Epsilon,Stau2,Pde4d,0.2661137053726865,0.0013694925687313408,destabilizing,0.0018012870877631855
+Epsilon,Stau2,Pkhd1,0.22810557246648216,0.006328485501964144,destabilizing,0.007030245632551577
+Epsilon,Stau2,Ctnna2,0.24569617093219714,0.0032061908292499676,destabilizing,0.003887987134270408
+Epsilon,Stau2,Ptprg,0.23019384413936989,0.005852324846245019,destabilizing,0.006613602875024859
+Epsilon,Stau2,Sox5,0.25610678237746975,0.002095402361290053,destabilizing,0.00265991715268783
+Epsilon,Stau2,Magi3,0.2944705479046463,0.00037480896438378335,destabilizing,0.0005937144848928306
+Epsilon,Stau2,Plcb1,0.25371256621338534,0.0023142779505934104,destabilizing,0.0029041408743103857
+Epsilon,Stau2,Hivep2,0.2859531432123199,0.0005611475325872161,destabilizing,0.0008466703612442121
+Epsilon,Stau2,Nlgn1,0.2727363030668042,0.001024227397513012,destabilizing,0.0013788630339400356
+Epsilon,Stau2,Camta1,0.2620221965460231,0.001632814195343916,destabilizing,0.002101492344007447
+Epsilon,Stau2,Gphn,0.22220674417937678,0.00786506815552476,destabilizing,0.008304727562078753
+Epsilon,Stau2,Dennd4c,0.23042068738156224,0.005802574898518512,destabilizing,0.006564052174112497
+Epsilon,Tardbp,Hs6st3,0.2771861311469901,0.0008391600955072047,destabilizing,0.001175246884387924
+Epsilon,Tardbp,Atp2c1,0.23894529455837454,0.004185936366699242,destabilizing,0.004920466426817713
+Epsilon,Tia1,Arhgef38,0.24886719696724818,0.0028217464813340325,destabilizing,0.003470997884118854
+Epsilon,Tra2b,Nlk,0.23514682675729073,0.004848331307435575,destabilizing,0.005620214398998297
+Epsilon,Upf1,Pdss2,0.24234524206050623,0.003663183041434542,destabilizing,0.004361305719566607
+Epsilon,Upf1,Auts2,0.22502443310133435,0.007094067288851087,destabilizing,0.007673738156811681
+Epsilon,Upf1,Mast4,-0.21629474675407856,0.009728092242346966,stabilizing,0.00979515953590721
+Epsilon,Upf1,Plekhg1,0.22492483237144012,0.007120132372888371,destabilizing,0.007686977862768804
+Epsilon,Ybx1,Mbd5,0.2259285253783691,0.006861318931940763,destabilizing,0.00747285666240757
+Epsilon,Ybx1,Pbx1,0.2883697186934372,0.0005010747707714462,destabilizing,0.0007696065540025529
+Epsilon,Ybx1,Cacna1c,0.23136456324532675,0.005599595426652644,destabilizing,0.006359089978877426
+Epsilon,Ybx1,Magi1,0.22263736320378694,0.007742629826438908,destabilizing,0.008223308851002928
+Epsilon,Ybx1,Ppp2r2b,0.25938032194314475,0.0018265126049503647,destabilizing,0.0023325550954902676
+Epsilon,Ybx1,Chrm3,-0.26882309534192583,0.0012170981680959764,stabilizing,0.0016131265350688032
+Epsilon,Ybx1,Fbxl17,0.22631832966580556,0.0067630798905079425,destabilizing,0.007422519840563595
+Epsilon,Ybx1,Med12l,0.23236763516499764,0.005390854021914536,destabilizing,0.006173665985961857
+Epsilon,Ybx1,Zyx,0.2781805442969772,0.0008022425524961439,destabilizing,0.0011393278651030806
+Epsilon,Ybx1,Dennd1b,0.2351272054691897,0.00485198365381148,destabilizing,0.005620214398998297
+Epsilon,Ybx1,Zc3h12c,0.3013447532806218,0.0002681348015088731,destabilizing,0.00044436050563020403
+Epsilon,Ybx1,Strbp,0.32208334018249085,9.274497009007024e-05,destabilizing,0.00017160134232971399
+Epsilon,Ythdf2,Ppp2r2b,0.22048436671216542,0.008372120720122648,destabilizing,0.008700746019417182
+Epsilon,Ythdf2,Fbxl17,0.26349649999115876,0.001533037477429505,destabilizing,0.001982253110350709
+Epsilon,Zfp36l1,2010111I01Rik,0.42281417718528047,1.589808330302294e-07,destabilizing,4.064061754703795e-07
+Epsilon,Zfp36l1,Cdk14,0.21740483757345336,0.009351157423277936,destabilizing,0.009531152204110967
+Epsilon,Zfp36l1,Dbndd2,0.23239528205751878,0.005385200395272113,destabilizing,0.0061735493191160725
+Epsilon,Zfp36l1,Trpm3,0.32981994940735193,6.116553636142392e-05,destabilizing,0.00011686611071117423
+Epsilon,Zfp36l1,Slc35f1,0.23239528205751878,0.005385200395272113,destabilizing,0.0061735493191160725
+Epsilon,Zfp36l1,Abtb2,0.23239528205751878,0.005385200395272113,destabilizing,0.0061735493191160725
+Ngn3 high EP,Elavl4,Ptprn2,0.2167745491889043,2.890049740296972e-08,destabilizing,8.136038762557552e-08
+Ngn3 high EP,Elavl4,Kcnh7,-0.24413573718638582,3.636357176930555e-10,stabilizing,1.2557854598592477e-09
+Ngn3 high EP,Elavl4,Pkhd1,-0.22338383800404998,1.0561293788220742e-08,stabilizing,3.098722610158698e-08
+Ngn3 high EP,Elavl4,Adgrb3,0.20921101318569876,8.799654141902068e-08,destabilizing,2.318771423174194e-07
+Ngn3 high EP,Elavl4,Naaladl2,-0.2551341163678383,5.35199361400169e-11,stabilizing,2.2289950931722394e-10
+Ngn3 high EP,Elavl4,Nrg1,0.27195435961807335,2.386348697381485e-12,destabilizing,1.2636284530896245e-11
+Ngn3 high EP,Elavl4,Magi1,-0.2634371990205529,1.184849232306105e-11,stabilizing,5.6791049410533993e-11
+Ngn3 high EP,Elavl4,Stxbp5l,0.288998124697179,8.128769975045126e-14,destabilizing,5.380471554910822e-13
+Ngn3 high EP,Elavl4,Nedd8,-0.22715390975557773,5.863606189290873e-09,stabilizing,1.7622513736463383e-08
+Ngn3 high EP,Elavl4,Rims2,0.2283198009143792,4.877781640946217e-09,destabilizing,1.4942405467581797e-08
+Ngn3 high EP,Elavl4,Pard3b,-0.22670895781811132,6.288689964139704e-09,stabilizing,1.880280387867174e-08
+Ngn3 high EP,Elavl4,Setbp1,-0.2632865101239552,1.2182996284766061e-11,stabilizing,5.81437419255788e-11
+Ngn3 high EP,Elavl4,Jazf1,0.20093929308106853,2.838379371471532e-07,destabilizing,6.952153879022783e-07
+Ngn3 high EP,Elavl4,Map7,-0.25043365020996156,1.22755636048522e-10,stabilizing,4.690868291613624e-10
+Ngn3 high EP,Elavl4,Shank2,-0.20445693241287416,1.7351923569787125e-07,stabilizing,4.4154093843485775e-07
+Ngn3 high EP,Elavl4,Chst9,0.2976377099771425,1.3396058734427273e-14,destabilizing,9.800274547817847e-14
+Ngn3 high EP,Elavl4,Asic2,0.24834783466629418,1.764750271248486e-10,destabilizing,6.476575252898733e-10
+Ngn3 high EP,Elavl4,Unc79,0.2278862808663725,5.223941589565351e-09,destabilizing,1.5871647671029154e-08
+Ngn3 high EP,Elavl4,Nol4,0.22109144336739897,1.5028275201262876e-08,destabilizing,4.340634291897225e-08
+Ngn3 high EP,Elavl4,Cacna1d,0.24818566544593285,1.815012625153986e-10,destabilizing,6.61735750547945e-10
+Ngn3 high EP,Hnrnpa1,Ptprn2,0.21981600915012617,1.825681586571241e-08,destabilizing,5.232365784193866e-08
+Ngn3 high EP,Hnrnpa1,Airn,-0.2701522741358563,3.3654437072087772e-12,stabilizing,1.7406387918214698e-11
+Ngn3 high EP,Hnrnpa1,Pkhd1,-0.27519033832698864,1.2788679229320285e-12,stabilizing,7.174327765634081e-12
+Ngn3 high EP,Hnrnpa1,Adgrb3,0.2412274917488547,5.943899557734986e-10,destabilizing,1.9848697622226138e-09
+Ngn3 high EP,Hnrnpa1,Map7,-0.23399562307375008,1.962673048757518e-09,stabilizing,6.182698102601586e-09
+Ngn3 high EP,Hnrnpa1,Auts2,-0.22935756378866098,4.137150883882578e-09,stabilizing,1.2743799952569049e-08
+Ngn3 high EP,Hnrnpa1,Shank2,-0.23634144280286748,1.3378949400685258e-09,stabilizing,4.262862960906019e-09
+Ngn3 high EP,Hnrnpa1,Hivep2,-0.24877332349737244,1.6392380710751383e-10,stabilizing,6.035869983561437e-10
+Ngn3 high EP,Hnrnpc,Kcnh7,0.23349346001115615,2.1293365900344586e-09,destabilizing,6.68876352575796e-09
+Ngn3 high EP,Hnrnpc,Magi1,0.2022532600724979,2.3641773628504995e-07,destabilizing,5.842144949977234e-07
+Ngn3 high EP,Hnrnpc,Slc28a3,0.24214750132153348,5.091664926007785e-10,destabilizing,1.7209517926202603e-09
+Ngn3 high EP,Nova1,Slit3,0.2706398878442734,3.067267687921017e-12,destabilizing,1.5938325555926035e-11
+Ngn3 high EP,Rbfox3,Ptprn2,0.30068642997520756,6.986650495287581e-15,destabilizing,5.4329757697620906e-14
+Ngn3 high EP,Rbfox3,Airn,-0.2538486963102044,6.72721608501641e-11,stabilizing,2.7502442229920025e-10
+Ngn3 high EP,Rbfox3,Kcnh7,-0.2678770286703308,5.175696694743066e-12,stabilizing,2.6042419568118956e-11
+Ngn3 high EP,Rbfox3,9030622O22Rik,-0.2525493669350644,8.465882207446877e-11,stabilizing,3.350199649352643e-10
+Ngn3 high EP,Rbfox3,Pkhd1,-0.38271807341406616,7.969832994364031e-24,stabilizing,1.846344643694334e-22
+Ngn3 high EP,Rbfox3,Adgrb3,0.3092343932066968,1.080463256476861e-15,destabilizing,9.535516993668805e-15
+Ngn3 high EP,Rbfox3,Cacna1a,0.2936292411133281,3.115994132428588e-14,destabilizing,2.1521648914662053e-13
+Ngn3 high EP,Rbfox3,Naaladl2,-0.32724197871423133,1.7267152958076107e-17,stabilizing,1.9395024332707708e-16
+Ngn3 high EP,Rbfox3,Traf5,-0.21839076019110407,2.266020385654352e-08,stabilizing,6.444538795006751e-08
+Ngn3 high EP,Rbfox3,Fam155a,0.21685691863856799,2.854572737142364e-08,destabilizing,8.056560618533779e-08
+Ngn3 high EP,Rbfox3,Mbd5,0.208583068323121,9.63417364680847e-08,destabilizing,2.5266983715214664e-07
+Ngn3 high EP,Rbfox3,Magi1,-0.3118048836549392,6.089662740513834e-16,stabilizing,5.643087472876153e-15
+Ngn3 high EP,Rbfox3,Tinagl1,-0.21276447752763886,5.241986366061714e-08,stabilizing,1.4357361672563118e-07
+Ngn3 high EP,Rbfox3,Stxbp5l,0.2345097348121229,1.8052004374205984e-09,destabilizing,5.702792290942346e-09
+Ngn3 high EP,Rbfox3,Nedd8,-0.2127216509562308,5.275098217679809e-08,stabilizing,1.4412553361326652e-07
+Ngn3 high EP,Rbfox3,Ror1,-0.273790846009259,1.6766009634702803e-12,stabilizing,9.037197041079853e-12
+Ngn3 high EP,Rbfox3,Zfp422,-0.24727526419541157,2.124165825682895e-10,stabilizing,7.669066227790193e-10
+Ngn3 high EP,Rbfox3,Ptprd,-0.22263033466809382,1.1864617412350456e-08,stabilizing,3.466221374391291e-08
+Ngn3 high EP,Rbfox3,Map7,-0.3264811120748192,2.068225343585725e-17,stabilizing,2.232880176764395e-16
+Ngn3 high EP,Rbfox3,Arhgap26,-0.21946201955721037,1.926598912013413e-08,stabilizing,5.507398432285129e-08
+Ngn3 high EP,Rbfox3,Auts2,-0.3267547439361786,1.938368773715004e-17,stabilizing,2.1132020356579259e-16
+Ngn3 high EP,Rbfox3,Kcnq1,-0.2114535767113086,6.352498151307649e-08,stabilizing,1.7263124022249454e-07
+Ngn3 high EP,Rbfox3,Cacna2d1,0.22106729277740972,1.5083919864637616e-08,destabilizing,4.3454194014189194e-08
+Ngn3 high EP,Rbfox3,Tenm3,-0.2273571172656989,5.678876637374077e-09,stabilizing,1.7113579460054128e-08
+Ngn3 high EP,Rbfox3,Shank2,-0.40160763051672393,2.8017482310947655e-26,stabilizing,7.988574443531743e-25
+Ngn3 high EP,Rbfox3,Chst9,0.21523453163327486,3.6375309452727956e-08,destabilizing,1.0188751665348486e-07
+Ngn3 high EP,Rbfox3,Hivep2,-0.3500811426753407,6.023920717516228e-20,stabilizing,8.81394715510269e-19
+Ngn3 high EP,Rbfox3,Nol4,0.21521326568243968,3.6490603259642784e-08,destabilizing,1.0195364528824818e-07
+Ngn3 high EP,Rbfox3,Slc28a3,-0.21031430391695452,7.499546030793658e-08,stabilizing,2.0143708179329824e-07
+Ngn3 high EP,Rbfox3,Arhgef38,-0.21035657483189213,7.453621840636424e-08,stabilizing,2.0068831687137295e-07
+Ngn3 high EP,Rbfox3,Gabbr2,0.2009797520129881,2.822498795361837e-07,destabilizing,6.92851801422155e-07
+Ngn3 high EP,Srsf3,Dbndd2,0.2527332909520005,8.195473150274546e-11,destabilizing,3.2586596793977374e-10
+Ngn3 high EP,Srsf3,Zc3h12c,0.2095847432011496,8.336595889199225e-08,destabilizing,2.2124808183268588e-07
+Ngn3 high EP,Ybx1,Kcnh7,0.21022660542946656,7.595697498701955e-08,destabilizing,2.0303883698453303e-07
+Ngn3 high EP,Ybx1,Med12l,0.21493256246079476,3.804597575727614e-08,destabilizing,1.0576781260522768e-07
+Ngn3 high EP,Ybx1,Dbndd2,0.2315523333474314,2.9127910177493373e-09,destabilizing,9.022349893418561e-09
+Ngn3 high EP,Zfp36l1,Ptprn2,-0.22642064898158812,6.579932827456849e-09,stabilizing,1.9563864449550844e-08
+Ngn3 high EP,Zfp36l1,Kcnh7,0.280621388442244,4.405788456363191e-13,destabilizing,2.6339982599332627e-12
+Ngn3 high EP,Zfp36l1,Pkhd1,0.26564513971921816,7.863598756388559e-12,destabilizing,3.903715096921463e-11
+Ngn3 high EP,Zfp36l1,Cacna1a,-0.25009128847370415,1.3032113942971494e-10,stabilizing,4.939710434593949e-10
+Ngn3 high EP,Zfp36l1,Naaladl2,0.2974768177668309,1.3861285627586358e-14,destabilizing,1.0074346155474529e-13
+Ngn3 high EP,Zfp36l1,Magi1,0.24482721946344568,3.23236185746441e-10,destabilizing,1.1338758313881462e-09
+Ngn3 high EP,Zfp36l1,Tinagl1,0.23166672993131984,2.859723676726749e-09,destabilizing,8.882717118771355e-09
+Ngn3 high EP,Zfp36l1,Gm20649,0.2226240202160665,1.1876172155063685e-08,destabilizing,3.466221374391291e-08
+Ngn3 high EP,Zfp36l1,Ror1,0.2500790314669103,1.3060025789304146e-10,destabilizing,4.939710434593949e-10
+Ngn3 high EP,Zfp36l1,Map7,0.22655147785750077,6.446185969809582e-09,destabilizing,1.921758390999532e-08
+Ngn3 high EP,Zfp36l1,Arhgap26,0.3027158583389788,4.510410680844106e-15,destabilizing,3.6344758529700333e-14
+Ngn3 high EP,Zfp36l1,Auts2,0.2852042645755182,1.759984689788025e-13,destabilizing,1.1247718247380942e-12
+Ngn3 high EP,Zfp36l1,Cacna2d1,-0.20842119875397705,9.861385856869556e-08,stabilizing,2.58020260537387e-07
+Ngn3 high EP,Zfp36l1,Tenm3,0.2527265328876798,8.205258185533871e-11,destabilizing,3.2586596793977374e-10
+Ngn3 high EP,Zfp36l1,Shank2,0.3207357922218318,7.949103848684585e-17,destabilizing,8.261124747417999e-16
+Ngn3 high EP,Zfp36l1,Hivep2,0.2989552769820447,1.012069807687193e-14,destabilizing,7.553165276162139e-14
+Ngn3 high EP,Zfp36l1,Arhgef38,0.26029414901968895,2.109945051475519e-11,destabilizing,9.460721359841843e-11
+Ngn3 high EP,Zfp36l1,Gabbr2,-0.20720146657157162,1.1747928086271368e-07,stabilizing,3.038068844635759e-07
+Ngn3 high EP,Zfp36l1,Atp2c1,0.22670748385185555,6.290146621282272e-09,destabilizing,1.880280387867174e-08
+Ngn3 low EP,Ago2,Stxbp5l,0.240141447817194,8.635370980894282e-05,destabilizing,0.00016084644105116317
+Ngn3 low EP,Ago2,Tmem164,0.2621072863094126,1.7260758149432276e-05,destabilizing,3.6011187733899984e-05
+Ngn3 low EP,Ago2,Farp1,-0.23503011493091316,0.00012301805471236766,stabilizing,0.0002242558636723817
+Ngn3 low EP,Ago2,Kif24,0.20296115188263122,0.0009532967641693676,destabilizing,0.0013006944806826218
+Ngn3 low EP,Celf2,Psmd13,0.20644651775934203,0.0007739699698236702,destabilizing,0.0011048197772065742
+Ngn3 low EP,Celf2,Pdss2,0.22551667446419957,0.0002328910765096756,destabilizing,0.0003900224052390953
+Ngn3 low EP,Cnot1,Hmg20a,0.2130324700850779,0.000517212583616655,destabilizing,0.0007878635520297538
+Ngn3 low EP,Ddx6,Cacna1a,0.24105762097216893,8.09800894440917e-05,destabilizing,0.00015159909000308076
+Ngn3 low EP,Elavl1,Psmd13,0.2979957171720331,8.993125533724301e-07,destabilizing,2.067295546234403e-06
+Ngn3 low EP,Elavl1,Gpc6,0.20219525767120386,0.0009975139256863108,destabilizing,0.001349434897035496
+Ngn3 low EP,Elavl1,Tmem164,0.2598677807743496,2.0477203189958603e-05,destabilizing,4.232462815470997e-05
+Ngn3 low EP,Elavl1,Elovl1,0.21283858784167164,0.0005234779223820333,destabilizing,0.0007963166206413421
+Ngn3 low EP,Elavl1,Eda,0.2041836490534019,0.0008864439614563693,destabilizing,0.0012245039566950093
+Ngn3 low EP,Elavl1,Farp1,-0.20612051695455091,0.0007893176050196971,stabilizing,0.0011224055969078046
+Ngn3 low EP,Elavl1,Tenm3,0.2075080770769826,0.0007258816059851367,destabilizing,0.0010534421438645064
+Ngn3 low EP,Elavl1,Zc3h12c,0.2101608511263726,0.0006175171150922333,destabilizing,0.0009192490387986123
+Ngn3 low EP,Esrp1,Ptprj,0.2033147740306198,0.0009334965476666575,destabilizing,0.0012817508101160993
+Ngn3 low EP,Fto,Idh3b,0.2054126856761878,0.0008236128709941716,destabilizing,0.0011578476770486962
+Ngn3 low EP,Fus,Macrod2,0.22047103180350863,0.00032324778363923025,destabilizing,0.0005224586270448023
+Ngn3 low EP,Fus,Ptprj,0.2492812234932989,4.498273905463804e-05,destabilizing,8.760211178416375e-05
+Ngn3 low EP,Fus,Nedd8,0.20358154954484078,0.0009188105540648279,destabilizing,0.0012660685701612003
+Ngn3 low EP,Fus,Tmem164,0.20694860056800113,0.0007508706435614237,destabilizing,0.0010787702269254562
+Ngn3 low EP,Fus,Exosc5,0.20654022837247232,0.0007696094554027924,destabilizing,0.0011000073449973075
+Ngn3 low EP,Fus,Robo2,0.2608421554460613,1.9013639804631837e-05,destabilizing,3.937275132728231e-05
+Ngn3 low EP,Fus,Pdss2,0.29150511758877,1.5824962551656724e-06,destabilizing,3.5839833721878365e-06
+Ngn3 low EP,Fus,Dnajb11,0.20803206672497965,0.0007031763407072496,destabilizing,0.001028858014297976
+Ngn3 low EP,Fus,Eda,0.219776530680638,0.0003379751476591535,destabilizing,0.0005431045725389865
+Ngn3 low EP,Fus,Tenm3,0.29798964362522395,8.997941046559812e-07,destabilizing,2.067295546234403e-06
+Ngn3 low EP,Fus,Dbndd2,0.2236387470237289,0.0002633408256780406,destabilizing,0.00043837574573949274
+Ngn3 low EP,Fus,Camta1,0.26857161606616536,1.0448697965786867e-05,destabilizing,2.2215969671042056e-05
+Ngn3 low EP,Fus,Zc3h12c,0.2067169561947831,0.0007614476559875722,destabilizing,0.0010917665398871195
+Ngn3 low EP,Fus,Kif24,0.22147194995339048,0.0003030705204424417,destabilizing,0.0004934325310863766
+Ngn3 low EP,Hnrnpa1,Ptprn2,0.2263046223677859,0.0002211208687080779,destabilizing,0.0003736875471176028
+Ngn3 low EP,Hnrnpa1,9030622O22Rik,0.20108326204828048,0.0010650793911197633,destabilizing,0.001424613880457862
+Ngn3 low EP,Hnrnpa1,Psmd13,0.24945808868571093,4.44076222015006e-05,destabilizing,8.678607361699238e-05
+Ngn3 low EP,Hnrnpa1,Macrod2,0.2625354891412407,1.6702975166809008e-05,destabilizing,3.497873518924975e-05
+Ngn3 low EP,Hnrnpa1,Gpc6,0.342495113378876,1.2682722926702758e-08,destabilizing,3.6822944894238815e-08
+Ngn3 low EP,Hnrnpa1,Ptprj,0.2703036168665005,9.113630693767322e-06,destabilizing,1.9602238552164916e-05
+Ngn3 low EP,Hnrnpa1,Tmem164,0.21800562544609967,0.0003784006326941581,destabilizing,0.0005977009993691816
+Ngn3 low EP,Hnrnpa1,Chchd3,0.2047390027254203,0.0008575251579327086,destabilizing,0.001193451784256786
+Ngn3 low EP,Hnrnpa1,Dach1,0.21894180944857428,0.00035650137347576334,destabilizing,0.0005671380934263932
+Ngn3 low EP,Hnrnpa1,Robo2,0.22254650754989572,0.000282717890710907,destabilizing,0.0004664425733984103
+Ngn3 low EP,Hnrnpa1,Rab28,0.23464437412316583,0.00012630817635627658,destabilizing,0.0002287535702087615
+Ngn3 low EP,Hnrnpa1,Pdss2,0.2935486533699088,1.3265377638302386e-06,destabilizing,3.0227663798754617e-06
+Ngn3 low EP,Hnrnpa1,Scmh1,0.22907323850632322,0.00018402208810354415,destabilizing,0.0003153044098168584
+Ngn3 low EP,Hnrnpa1,Tenm3,0.2583922172658435,2.289812011495576e-05,destabilizing,4.697916894433727e-05
+Ngn3 low EP,Hnrnpa1,Sh3d19,-0.20453871465756587,0.0008678529106060247,stabilizing,0.0012019130415949577
+Ngn3 low EP,Hnrnpa1,Hmg20a,0.22584361307673775,0.00022793810778188656,destabilizing,0.00038231837628935767
+Ngn3 low EP,Hnrnpa1,Dbndd2,0.21444935787583114,0.00047349255481417057,destabilizing,0.0007292572312373375
+Ngn3 low EP,Hnrnpa1,Dapk1,0.272970099782597,7.370337298506224e-06,destabilizing,1.6007451320193204e-05
+Ngn3 low EP,Hnrnpa1,Zc3h12c,0.27199572821709106,7.96696375733936e-06,destabilizing,1.720245378283761e-05
+Ngn3 low EP,Hnrnpa1,2410018L13Rik,0.2162796837955172,0.0004220840043029159,destabilizing,0.0006610667785702007
+Ngn3 low EP,Hnrnpa1,Kif24,0.26292440742195167,1.6211203321455115e-05,destabilizing,3.404118289618865e-05
+Ngn3 low EP,Hnrnpa2b1,Psmd13,0.24390913389434662,6.619703184273619e-05,destabilizing,0.00012604640309781274
+Ngn3 low EP,Hnrnpa2b1,Pdss2,0.23217847937538272,0.00014936854646726842,destabilizing,0.0002640664923236923
+Ngn3 low EP,Hnrnpa2b1,Tenm3,0.26840868468637286,1.0583425141176615e-05,destabilizing,2.2416304749278903e-05
+Ngn3 low EP,Hnrnpa2b1,Dapk1,0.20781123344372465,0.0007126641803645111,destabilizing,0.0010372808489075083
+Ngn3 low EP,Hnrnpa2b1,Zc3h12c,0.20455983591201082,0.0008667584204729098,destabilizing,0.0012019130415949577
+Ngn3 low EP,Hnrnpc,Psmd13,0.21708760198629384,0.00040108342675217526,destabilizing,0.0006308412596158682
+Ngn3 low EP,Hnrnpc,Gpc6,0.2259231207515394,0.0002267485521969197,destabilizing,0.000381458986449281
+Ngn3 low EP,Hnrnpc,Tmem164,0.20178251717110912,0.0010221179390815863,destabilizing,0.0013788630339400356
+Ngn3 low EP,Hnrnpc,Elovl1,0.2018940188857316,0.001015416697776496,destabilizing,0.0013719846511876836
+Ngn3 low EP,Hnrnpc,Dapk1,0.20520774964629349,0.0008337958266092955,destabilizing,0.001169206758120475
+Ngn3 low EP,Hnrnpd,Airn,-0.23387901251750712,0.00013308177447944182,stabilizing,0.00023830424029168973
+Ngn3 low EP,Hnrnpd,Macrod2,0.23110902746550746,0.00016054758533558616,destabilizing,0.0002811478974695619
+Ngn3 low EP,Hnrnpd,Ppp2r2b,0.20908531704652406,0.000659509506669787,destabilizing,0.0009713570482341764
+Ngn3 low EP,Hnrnpd,Gpc6,0.3740390523966486,4.00390241791794e-10,destabilizing,1.3784332782429564e-09
+Ngn3 low EP,Hnrnpd,Ptprj,0.21847695536232487,0.0003672235972651942,destabilizing,0.0005825287306118345
+Ngn3 low EP,Hnrnpd,Rims2,0.2190586212045787,0.00035385316397517545,destabilizing,0.0005645404854238093
+Ngn3 low EP,Hnrnpd,Nos1ap,0.21313777212558221,0.0005138389198884231,destabilizing,0.0007837981878133422
+Ngn3 low EP,Hnrnpd,Jazf1,0.20149703276375464,0.0010394614330779051,destabilizing,0.0013959916830708096
+Ngn3 low EP,Hnrnpd,Exosc5,0.22861710737295757,0.00018970421584661658,destabilizing,0.0003240416098639595
+Ngn3 low EP,Hnrnpd,Chchd3,0.20749825792234428,0.0007263134761696939,destabilizing,0.0010534421438645064
+Ngn3 low EP,Hnrnpd,Dach1,0.2316515910477137,0.00015478180558198179,destabilizing,0.0002727692041317967
+Ngn3 low EP,Hnrnpd,Pdss2,0.30696514572562467,4.0247072082353143e-07,destabilizing,9.687174059648636e-07
+Ngn3 low EP,Hnrnpd,Mast4,0.20553510534433084,0.0008175848795141694,destabilizing,0.0011508283367338689
+Ngn3 low EP,Hnrnpd,Dnajb11,0.23487971311043593,0.0001242912144440356,destabilizing,0.00022546791266193732
+Ngn3 low EP,Hnrnpd,Eda,0.28279490003086805,3.3060017960216217e-06,destabilizing,7.382076299550288e-06
+Ngn3 low EP,Hnrnpd,Tenm3,0.38605226587787933,9.701078204114958e-11,destabilizing,3.7984503390759974e-10
+Ngn3 low EP,Hnrnpd,Med12l,0.22765160441280133,0.00020227672533358647,destabilizing,0.0003439322913928871
+Ngn3 low EP,Hnrnpd,Hmg20a,0.24728532245668292,5.197876962519974e-05,destabilizing,0.00010034790247087172
+Ngn3 low EP,Hnrnpd,Slc35f1,0.20273502218137818,0.0009661603203836009,destabilizing,0.0013150186980006907
+Ngn3 low EP,Hnrnpd,Slc28a3,0.21004338012882998,0.0006219801858439018,destabilizing,0.0009234205162328689
+Ngn3 low EP,Hnrnpd,Camta1,0.23592311211420786,0.00011570702205490335,destabilizing,0.00021162205349515217
+Ngn3 low EP,Hnrnpd,Kif24,0.24056405444994167,8.383466934409565e-05,destabilizing,0.0001566792475808981
+Ngn3 low EP,Igf2bp2,Glis3,-0.21007015103815344,0.0006209604625801722,stabilizing,0.0009231390834079566
+Ngn3 low EP,Matr3,Rapgef4,0.20700672886868055,0.0007482378478973601,destabilizing,0.0010772242638442437
+Ngn3 low EP,Matr3,Kif24,0.20889817543921785,0.0006670803214637998,destabilizing,0.000979911912110628
+Ngn3 low EP,Mettl14,Chrm3,0.2283888313108283,0.00019260906400098601,destabilizing,0.0003284988944311295
+Ngn3 low EP,Msi1,Adgrb3,0.251086582485922,3.942841316310382e-05,destabilizing,7.760069988915302e-05
+Ngn3 low EP,Msi1,Kcnma1,0.22501570113234917,0.00024067576417133215,destabilizing,0.00040184902366144343
+Ngn3 low EP,Msi1,Kcnb2,0.23285434161025614,0.0001426840090729703,destabilizing,0.0002538633889426288
+Ngn3 low EP,Msi1,Cadps,0.22757860714925782,0.00020325824603563763,destabilizing,0.0003450735413612657
+Ngn3 low EP,Msi1,Grik2,0.2521515053916368,3.646248738488402e-05,destabilizing,7.201826993248851e-05
+Ngn3 low EP,Msi1,Megf11,0.23242416004174796,0.00014690546678735905,destabilizing,0.00026030010969470426
+Ngn3 low EP,Msi1,Nol4,0.391232828172896,5.17012172325298e-11,destabilizing,2.1695001344367221e-10
+Ngn3 low EP,Msi1,Gabbr2,0.2521515053916368,3.646248738488402e-05,destabilizing,7.201826993248851e-05
+Ngn3 low EP,Ptbp1,Macrod2,0.21945482058103344,0.0003450066464662572,destabilizing,0.0005528060387182679
+Ngn3 low EP,Ptbp1,Gpc6,0.30081077956920244,7.00777533836669e-07,destabilizing,1.6405570897397388e-06
+Ngn3 low EP,Ptbp1,Nos1ap,0.2030395965826876,0.0009488713536789096,destabilizing,0.0012978412611204767
+Ngn3 low EP,Ptbp1,Rapgef4,0.21395415058676406,0.0004883675302595792,destabilizing,0.0007511268238570568
+Ngn3 low EP,Ptbp1,Jazf1,0.26219864062736475,1.714029800739421e-05,destabilizing,3.582708906808714e-05
+Ngn3 low EP,Ptbp1,Exosc5,0.2091188218973228,0.0006581624807118548,destabilizing,0.0009706587248694728
+Ngn3 low EP,Ptbp1,Chchd3,0.2058118910147195,0.0008041055718071611,destabilizing,0.0011405170865428102
+Ngn3 low EP,Ptbp1,Dock4,0.20004467962024036,0.0011319607604719953,destabilizing,0.0015056702938335631
+Ngn3 low EP,Ptbp1,Cdk14,0.2162365122352687,0.00042323441699737487,destabilizing,0.0006619362471182572
+Ngn3 low EP,Ptbp1,Tenm3,0.23370268591348814,0.0001346898059130002,destabilizing,0.00024079592311134442
+Ngn3 low EP,Ptbp1,Hmg20a,0.2157652412834832,0.0004359833356771129,destabilizing,0.0006752276730821025
+Ngn3 low EP,Ptbp2,Tecpr2,-0.20749152317031927,0.0007266098240504284,stabilizing,0.0010534421438645064
+Ngn3 low EP,Pum2,Macrod2,0.20280446968359508,0.0009621928432509873,destabilizing,0.0013112235805086984
+Ngn3 low EP,Pum2,Ptprj,0.21335457074392772,0.0005069572518278185,destabilizing,0.0007775675365965988
+Ngn3 low EP,Pum2,Rapgef4,0.2321346052712163,0.00014981245530216856,destabilizing,0.00026443087348573244
+Ngn3 low EP,Pum2,Tenm3,0.218974013754031,0.0003557694439970492,destabilizing,0.0005667845583448692
+Ngn3 low EP,Rbfox2,Snd1,0.21244544739943513,0.0005363987565326384,destabilizing,0.0008137454532937161
+Ngn3 low EP,Rbfox3,Ptprn2,0.23241425613712136,0.0001470040187844193,destabilizing,0.00026030010969470426
+Ngn3 low EP,Rbfox3,Adgrb3,0.22242518954301327,0.00028495023780183764,destabilizing,0.00046942913249724955
+Ngn3 low EP,Rbfox3,Arl15,0.20896363285218908,0.0006644231530587721,destabilizing,0.000977299664287506
+Ngn3 low EP,Rbfox3,Grik2,0.220597182354876,0.00032063762468368973,destabilizing,0.0005197507852015495
+Ngn3 low EP,Rbfox3,Megf11,0.2151779106629348,0.0004523707861836454,destabilizing,0.0006986615475502968
+Ngn3 low EP,Srsf1,Macrod2,0.2689260736236957,1.0161201587774063e-05,destabilizing,2.1646084608438232e-05
+Ngn3 low EP,Srsf1,Gpc6,0.32375419988929177,8.302508905309035e-08,destabilizing,2.2124808183268588e-07
+Ngn3 low EP,Srsf1,Ptprj,0.2959317249852375,1.0779831659483856e-06,destabilizing,2.471582021720835e-06
+Ngn3 low EP,Srsf1,Jazf1,0.21151083408140242,0.0005683106031900015,destabilizing,0.0008551574976282566
+Ngn3 low EP,Srsf1,Tenm3,0.21103396205284486,0.0005852620258018328,destabilizing,0.0008782879523503888
+Ngn3 low EP,Srsf1,Med12l,0.2198936096724867,0.00033544944941571307,destabilizing,0.0005398260314765165
+Ngn3 low EP,Srsf1,Chst9,0.24676460292116156,5.39658833953792e-05,destabilizing,0.00010382363725893023
+Ngn3 low EP,Srsf1,Hmg20a,0.3202460542279156,1.1639862160084275e-07,destabilizing,3.017139096040493e-07
+Ngn3 low EP,Srsf1,Drg1,0.20633739303544715,0.0007790764615890506,destabilizing,0.0011106833657525952
+Ngn3 low EP,Srsf1,Dapk1,0.2742761590287787,6.636969983857862e-06,destabilizing,1.4471197298137142e-05
+Ngn3 low EP,Srsf1,Slc28a3,0.2545945360590869,3.043453529432768e-05,destabilizing,6.086907058865536e-05
+Ngn3 low EP,Srsf1,Kif24,0.22807307872372046,0.00019669560927744727,destabilizing,0.0003349548507144278
+Ngn3 low EP,Srsf3,Macrod2,0.37500948438425824,3.57831018318104e-10,destabilizing,1.241929813595612e-09
+Ngn3 low EP,Srsf3,Ttll3,0.25080931084820374,4.023719321701431e-05,destabilizing,7.905257748643094e-05
+Ngn3 low EP,Srsf3,Gpc6,0.37771229894953445,2.611516796026624e-10,destabilizing,9.307713708915404e-10
+Ngn3 low EP,Srsf3,Ptprj,0.369495402826764,6.743036878768943e-10,destabilizing,2.2382856743853924e-09
+Ngn3 low EP,Srsf3,Gm20649,0.23083900035271068,0.00016349145432491795,destabilizing,0.00028585298303350433
+Ngn3 low EP,Srsf3,Tmem164,0.3177249260370653,1.4799679565902548e-07,destabilizing,3.815447458531517e-07
+Ngn3 low EP,Srsf3,Zfp422,-0.21941080017472356,0.0003459792974105589,stabilizing,0.0005535668758568943
+Ngn3 low EP,Srsf3,Rapgef4,0.2871949608979941,2.2856447934250237e-06,destabilizing,5.145014190867665e-06
+Ngn3 low EP,Srsf3,Jazf1,0.42294216543325763,8.576453592203249e-13,destabilizing,4.941459271777209e-12
+Ngn3 low EP,Srsf3,Ctnna2,0.2334408859079992,0.0001371109243858622,destabilizing,0.00024473089553303176
+Ngn3 low EP,Srsf3,Exosc5,0.33019570969122053,4.41453436169116e-08,destabilizing,1.218104766799149e-07
+Ngn3 low EP,Srsf3,Chchd3,0.21319562653119312,0.0005119940735259914,destabilizing,0.0007831326131511725
+Ngn3 low EP,Srsf3,Dock4,0.20668620535094112,0.0007628620517017013,destabilizing,0.0010917665398871195
+Ngn3 low EP,Srsf3,Sik3,-0.20503679004657588,0.0008423792408123798,stabilizing,0.0011767911002303598
+Ngn3 low EP,Srsf3,Robo2,0.242813100547757,7.155017586993917e-05,destabilizing,0.00013554309295974847
+Ngn3 low EP,Srsf3,Ptprk,-0.34797768086936504,7.145886484456867e-09,stabilizing,2.1189935388576096e-08
+Ngn3 low EP,Srsf3,Pdss2,0.31491968995730485,1.9283621213032358e-07,destabilizing,4.862445983875734e-07
+Ngn3 low EP,Srsf3,Pik3ap1,0.2332817927667993,0.00013860206101280216,destabilizing,0.0002469959805228141
+Ngn3 low EP,Srsf3,Auts2,-0.2629136136671368,1.6224664509874084e-05,stabilizing,3.404118289618865e-05
+Ngn3 low EP,Srsf3,Plcb1,0.23948781265286198,9.039028964797548e-05,destabilizing,0.000167803008495073
+Ngn3 low EP,Srsf3,Eda,0.25624974397839456,2.6899613649610145e-05,destabilizing,5.458461747877095e-05
+Ngn3 low EP,Srsf3,Tenm3,0.3785020174577686,2.3806105746126795e-10,destabilizing,8.539480512804193e-10
+Ngn3 low EP,Srsf3,Shank2,-0.2777502497411461,5.009001324396358e-06,stabilizing,1.1029721728175742e-05
+Ngn3 low EP,Srsf3,Med12l,0.2446182177935103,6.293704635757916e-05,destabilizing,0.00012004458927895032
+Ngn3 low EP,Srsf3,Chst9,0.3361297654130816,2.435021372305866e-08,destabilizing,6.907509607153375e-08
+Ngn3 low EP,Srsf3,Hmg20a,0.40168484704855967,1.4040143411010854e-11,destabilizing,6.532485135164883e-11
+Ngn3 low EP,Srsf3,Dbndd2,0.25548415694103616,2.8483442840765944e-05,destabilizing,5.7172542308541024e-05
+Ngn3 low EP,Srsf3,Nckap5,0.22163097548219632,0.00029997485807979607,destabilizing,0.0004898267873490943
+Ngn3 low EP,Srsf3,Dapk1,0.20570444807899224,0.0008093134481206532,destabilizing,0.0011464414704588106
+Ngn3 low EP,Srsf3,Slc35f1,0.20507622075694798,0.0008403923343975645,destabilizing,0.0011754921708806185
+Ngn3 low EP,Srsf3,Slc28a3,0.21329137684106117,0.0005089542935092808,destabilizing,0.0007795553366147661
+Ngn3 low EP,Srsf3,Fmnl2,0.25946846406932206,2.110728156732476e-05,destabilizing,4.3465365005305804e-05
+Ngn3 low EP,Srsf3,Camta1,0.28456764671700724,2.851338218529526e-06,destabilizing,6.379654122746143e-06
+Ngn3 low EP,Srsf3,Zc3h12c,0.2055952754498606,0.0008146370213960888,destabilizing,0.0011481322785709134
+Ngn3 low EP,Srsf3,Gphn,-0.23649184874244072,0.00011126525276298544,stabilizing,0.00020450737367345425
+Ngn3 low EP,Srsf3,Kif24,0.44228425303518903,5.650082879658229e-14,destabilizing,3.7622108755568566e-13
+Ngn3 low EP,Stau2,Slc35f1,0.21954649227240494,0.0003429892754576743,destabilizing,0.000550366629594421
+Ngn3 low EP,Tardbp,Ppp2r2b,0.2427693216274159,7.17722290757202e-05,destabilizing,0.00013573251485068173
+Ngn3 low EP,Tardbp,Chchd3,0.20453726239772196,0.0008679282125906033,destabilizing,0.0012019130415949577
+Ngn3 low EP,Tardbp,Pdss2,0.2462157868629376,5.6137545107424776e-05,destabilizing,0.00010762922441285578
+Ngn3 low EP,Tardbp,Dnajb11,0.20268316897706679,0.0009691324662636853,destabilizing,0.0013174514700308288
+Ngn3 low EP,Tardbp,Tenm3,0.22909542802702562,0.00018374976741956193,destabilizing,0.0003153044098168584
+Ngn3 low EP,Tia1,Adgrb3,0.40274279906878807,1.2273164615068418e-11,destabilizing,5.832375663229095e-11
+Ngn3 low EP,Tia1,Grik2,0.3995885195634811,1.8302589502986283e-11,destabilizing,8.307134500947244e-11
+Ngn3 low EP,Tial1,Exoc6b,-0.21579042500729403,0.0004352931446548589,stabilizing,0.0006750989914312456
+Ngn3 low EP,Tial1,Pdss2,0.21742424585680636,0.0003926227739694716,destabilizing,0.000618408675147383
+Ngn3 low EP,Tial1,Tenm3,0.2079934191189977,0.0007048283190173815,destabilizing,0.0010299199615602212
+Ngn3 low EP,Tial1,Med12l,0.22386597014057147,0.00025946852027943824,destabilizing,0.0004325772032244907
+Ngn3 low EP,Tial1,Zc3h12c,0.23435453971672984,0.0001288343387887499,destabilizing,0.00023181842189820372
+Ngn3 low EP,Tra2b,Macrod2,0.20241654266154918,0.0009845484435904491,destabilizing,0.0013367739551557747
+Ngn3 low EP,Tra2b,Ttll3,0.20976529489394644,0.0006326646539716481,destabilizing,0.0009367817512869143
+Ngn3 low EP,Tra2b,Sntb1,0.2070770571456577,0.0007450638757746783,destabilizing,0.0010762653718152128
+Ngn3 low EP,Tra2b,Gpc6,0.3208640884370732,1.0970642935549364e-07,destabilizing,2.850316575778246e-07
+Ngn3 low EP,Tra2b,Ptprj,0.2467884266113212,5.387342927000811e-05,destabilizing,0.00010382363725893023
+Ngn3 low EP,Tra2b,Rims2,0.2438158977014819,6.663731338216894e-05,destabilizing,0.0001266678503948237
+Ngn3 low EP,Tra2b,Rapgef4,0.20560310705794968,0.0008142540566498908,destabilizing,0.0011481322785709134
+Ngn3 low EP,Tra2b,Cadps,0.2217358951518851,0.000297948592273245,destabilizing,0.00048795115553438656
+Ngn3 low EP,Tra2b,Jazf1,0.27276009207874263,7.495222056407998e-06,destabilizing,1.6246953073539363e-05
+Ngn3 low EP,Tra2b,Ptprd,0.20479278871163692,0.0008547710762241322,destabilizing,0.0011926040611809725
+Ngn3 low EP,Tra2b,Eda,0.2158599382716079,0.0004333933071222254,destabilizing,0.0006730912814523947
+Ngn3 low EP,Tra2b,Tenm3,0.2704533618127827,9.006149709997274e-06,destabilizing,1.940860170061428e-05
+Ngn3 low EP,Tra2b,Shank2,-0.22913207510617653,0.0001833008410386963,stabilizing,0.00031503946713296797
+Ngn3 low EP,Tra2b,Med12l,0.23459756749804658,0.00012671296980783188,destabilizing,0.0002291135324005025
+Ngn3 low EP,Tra2b,Chst9,0.23489860059279688,0.00012413065556112556,destabilizing,0.00022546791266193732
+Ngn3 low EP,Tra2b,Hmg20a,0.26815982379988074,1.0792394613692311e-05,destabilizing,2.27725670027056e-05
+Ngn3 low EP,Tra2b,Dbndd2,0.2085970842876563,0.0006794297518194742,destabilizing,0.000996306318340003
+Ngn3 low EP,Tra2b,Gphn,-0.2168590579967841,0.0004069234461780809,stabilizing,0.0006391227007768728
+Ngn3 low EP,Tra2b,Kif24,0.35193368465002306,4.6911085439415665e-09,destabilizing,1.4410256079732107e-08
+Ngn3 low EP,Ybx1,Arl15,0.21812776132328585,0.0003754743657355704,destabilizing,0.0005939224675646577
+Ngn3 low EP,Ybx1,Psmd13,0.25720508401964315,2.503987353233893e-05,destabilizing,5.1090530950386956e-05
+Ngn3 low EP,Ybx1,Macrod2,0.3608480164614618,1.7785001687527048e-09,destabilizing,5.650549107580022e-09
+Ngn3 low EP,Ybx1,Ttll3,0.22898493149894933,0.00018510957699768496,destabilizing,0.00031667976864834717
+Ngn3 low EP,Ybx1,Ppp2r2b,0.3066557792772371,4.1397418498579524e-07,destabilizing,9.942533341343505e-07
+Ngn3 low EP,Ybx1,Gpc6,0.38225713293908486,1.5276849970797106e-10,destabilizing,5.643806367948964e-10
+Ngn3 low EP,Ybx1,Ptprj,0.3608014113704469,1.7876814203596944e-09,destabilizing,5.663537719202223e-09
+Ngn3 low EP,Ybx1,Tmem164,0.29545355931646355,1.123976954102823e-06,destabilizing,2.5717332777002864e-06
+Ngn3 low EP,Ybx1,Rapgef4,0.25597999053998444,2.744792547045214e-05,destabilizing,5.549471476935051e-05
+Ngn3 low EP,Ybx1,Jazf1,0.3157562128036365,1.7825340727461438e-07,destabilizing,4.515211592013011e-07
+Ngn3 low EP,Ybx1,Large,0.25565863262519134,2.8114921459172585e-05,destabilizing,5.6637305548188245e-05
+Ngn3 low EP,Ybx1,Exosc5,0.30546822440526583,4.611308988250767e-07,destabilizing,1.1027474397709362e-06
+Ngn3 low EP,Ybx1,Elovl1,0.2597274035022492,2.069664590883353e-05,destabilizing,4.269883163380869e-05
+Ngn3 low EP,Ybx1,Chchd3,0.238273470233608,9.836407262678506e-05,destabilizing,0.0001813944423896932
+Ngn3 low EP,Ybx1,Sik3,-0.2023341074833148,0.0009893602270241138,stabilizing,0.0013416689907936763
+Ngn3 low EP,Ybx1,Pawr,0.27397438020297665,6.7999851819707095e-06,destabilizing,1.4797619417517474e-05
+Ngn3 low EP,Ybx1,Robo2,0.21271068025942583,0.0005276496995476441,destabilizing,0.0008015662102417763
+Ngn3 low EP,Ybx1,Ptprk,-0.2352925315495385,0.00012082590588797742,stabilizing,0.00022062135853436927
+Ngn3 low EP,Ybx1,Sox5,0.23989741700425024,8.784051610900627e-05,destabilizing,0.0001633422306241053
+Ngn3 low EP,Ybx1,Rab28,0.2885278103209923,2.041339943574996e-06,destabilizing,4.604401657718855e-06
+Ngn3 low EP,Ybx1,Arhgap26,-0.21855534507092136,0.00036539471452052674,stabilizing,0.0005804556036383225
+Ngn3 low EP,Ybx1,Pdss2,0.35735644443032427,2.609712997425418e-09,destabilizing,8.151687789710856e-09
+Ngn3 low EP,Ybx1,Auts2,-0.23752523880993826,0.00010360108709894347,stabilizing,0.000190735776248386
+Ngn3 low EP,Ybx1,Plcb1,0.20943994337035274,0.0006453805442661471,destabilizing,0.0009530719325683341
+Ngn3 low EP,Ybx1,Egln2,0.2097088014782309,0.0006348558588797901,destabilizing,0.0009387762168541577
+Ngn3 low EP,Ybx1,Dnajb11,0.21913588120785496,0.00035211168442336705,destabilizing,0.0005625692429292875
+Ngn3 low EP,Ybx1,Eda,0.2813768719524478,3.7186398385714183e-06,destabilizing,8.253747505970893e-06
+Ngn3 low EP,Ybx1,Farp1,-0.2473362157868903,5.178829877723147e-05,stabilizing,0.0001001540665048372
+Ngn3 low EP,Ybx1,Tenm3,0.39429033171502537,3.5476479743209133e-11,destabilizing,1.517301749017252e-10
+Ngn3 low EP,Ybx1,Med12l,0.234378890687461,0.00012862029063414815,destabilizing,0.00023180836820935614
+Ngn3 low EP,Ybx1,Chst9,0.28173598859064686,3.6097268855031265e-06,destabilizing,8.028032593358954e-06
+Ngn3 low EP,Ybx1,Sh3d19,-0.21034508583377293,0.0006105771247658728,stabilizing,0.0009125830144350143
+Ngn3 low EP,Ybx1,Hmg20a,0.36558522984577424,1.0492177787516987e-09,destabilizing,3.3720525143696213e-09
+Ngn3 low EP,Ybx1,Dbndd2,0.2308124141243304,0.000163784015110089,destabilizing,0.00028591495259406435
+Ngn3 low EP,Ybx1,Nckap5,0.2485372064523103,4.747987417151779e-05,destabilizing,9.214244341837309e-05
+Ngn3 low EP,Ybx1,Dapk1,0.31039753774987366,2.9376427150176415e-07,destabilizing,7.179469668350807e-07
+Ngn3 low EP,Ybx1,Slc35f1,0.27473068332757733,6.398442038901502e-06,destabilizing,1.4006038478855257e-05
+Ngn3 low EP,Ybx1,Slc28a3,0.2794133010590294,4.371740619475289e-06,destabilizing,9.684015077403428e-06
+Ngn3 low EP,Ybx1,Cers6,0.21315911364434054,0.0005131576711330093,destabilizing,0.0007837981878133422
+Ngn3 low EP,Ybx1,Cacna1d,0.25659283110360825,2.621719360071923e-05,destabilizing,5.329711020840911e-05
+Ngn3 low EP,Ybx1,Fmnl2,0.2576137104504046,2.428212800107552e-05,destabilizing,4.9635526355139665e-05
+Ngn3 low EP,Ybx1,Camta1,0.2689340322961113,1.0154833441347818e-05,destabilizing,2.1646084608438232e-05
+Ngn3 low EP,Ybx1,Zc3h12c,0.22190112431145279,0.00029478341931488936,destabilizing,0.0004839244103541263
+Ngn3 low EP,Ybx1,Gphn,-0.24534937608488563,5.973418910894828e-05,stabilizing,0.0001143277423221179
+Ngn3 low EP,Ybx1,Kif24,0.4649332102641078,1.862878992134688e-15,destabilizing,1.59347803019521e-14
+Ngn3 low EP,Ythdf2,Gpc6,0.20174953858862024,0.0010241077323406664,destabilizing,0.0013788630339400356
+Ngn3 low EP,Ythdf2,Abtb2,0.20699373006394509,0.0007488258596687054,destabilizing,0.0010772242638442437
+Pre-endocrine,Hnrnpa1,Adgrb3,0.25509553786355116,3.012873178511673e-10,destabilizing,1.0635920553984066e-09
+Pre-endocrine,Hnrnpa1,Traf5,-0.20282781381909973,6.477776018333338e-07,stabilizing,1.5261201127937863e-06
+Pre-endocrine,Hnrnpa1,Kcnb2,0.21638956463152817,1.0550384827353305e-07,destabilizing,2.7475475241257315e-07
+Pre-endocrine,Hnrnpa1,Snd1,0.25238665223696427,4.695085211806233e-10,destabilizing,1.5917484010757717e-09
+Pre-endocrine,Hnrnpa1,Pde1c,0.21809665383392954,8.324043512265246e-08,destabilizing,2.2124808183268588e-07
+Pre-endocrine,Hnrnpa1,Maml3,0.21127314996452623,2.1221072646240532e-07,destabilizing,5.302883771375162e-07
+Pre-endocrine,Hnrnpa1,Phactr1,-0.2032877260417254,6.103121656986348e-07,stabilizing,1.4439726133125146e-06
+Pre-endocrine,Hnrnpa1,Smim10l1,-0.20742408803084547,3.5494706727843163e-07,stabilizing,8.599153351059172e-07
+Pre-endocrine,Hnrnpa1,Grik2,0.21982201358244463,6.538001407791557e-08,destabilizing,1.768919115684723e-07
+Pre-endocrine,Hnrnpa1,Cacna2d1,0.2985614158534873,1.181628502404823e-13,destabilizing,7.63936566671025e-13
+Pre-endocrine,Hnrnpa1,Megf11,0.30497562584517857,3.2953513428930785e-14,destabilizing,2.2619942551216685e-13
+Pre-endocrine,Hnrnpa1,Nol4,0.26071406364964755,1.1808564493125665e-10,destabilizing,4.527973695295083e-10
+Pre-endocrine,Hnrnpa1,Gabbr2,0.20252783705484056,6.733952181493268e-07,destabilizing,1.583119413492709e-06
+Pre-endocrine,Mbnl2,Ppp2r2b,0.21246031413697472,1.8072314511281234e-07,destabilizing,4.5673667583056213e-07
+Pre-endocrine,Mbnl2,Pde1c,-0.21137676981157458,2.0926424048545746e-07,stabilizing,5.241032329275421e-07
+Pre-endocrine,Mbnl2,Unc5c,0.24651241776110136,1.2071430947148682e-09,destabilizing,3.868423980757733e-09
+Pre-endocrine,Mbnl2,Cacna2d1,-0.2700121277627229,2.3851057229809835e-11,stabilizing,1.0608950255819415e-10
+Pre-endocrine,Mbnl2,Shank2,0.28020878688093326,3.8405538740698245e-12,destabilizing,1.9680626303989146e-11
+Pre-endocrine,Mbnl2,Megf11,-0.22247817505561518,4.4904171200216924e-08,stabilizing,1.2329244043121288e-07
+Pre-endocrine,Rbfox3,Ptprn2,0.21272335186807645,1.7438299499891285e-07,destabilizing,4.427257772575139e-07
+Pre-endocrine,Rbfox3,Adgrb3,0.2858750972426859,1.3467671959169328e-12,destabilizing,7.45077175054542e-12
+Pre-endocrine,Rbfox3,Rora,-0.213646828011577,1.537786345910759e-07,stabilizing,3.940134600582406e-07
+Pre-endocrine,Rbfox3,Traf5,-0.21913198111490179,7.202729410725675e-08,stabilizing,1.944037646778386e-07
+Pre-endocrine,Rbfox3,Sdk1,-0.22284697876841134,4.2605991721395315e-08,stabilizing,1.1785538008505371e-07
+Pre-endocrine,Rbfox3,Snd1,0.22616865816520068,2.6435779339093482e-08,destabilizing,7.480047487295662e-08
+Pre-endocrine,Rbfox3,Pde1c,0.21649070232638973,1.040383076510211e-07,destabilizing,2.715741739622898e-07
+Pre-endocrine,Rbfox3,Maml3,0.21078429321061173,2.2665949742779745e-07,destabilizing,5.613482430728525e-07
+Pre-endocrine,Rbfox3,Ror1,-0.2349296631880901,7.244175662785937e-09,stabilizing,2.1424264194196705e-08
+Pre-endocrine,Rbfox3,Pcdh9,-0.2112277303683529,2.1351482612903403e-07,stabilizing,5.323508669405513e-07
+Pre-endocrine,Rbfox3,Elovl1,0.20341004156296788,6.007042804983209e-07,destabilizing,1.4242711298808802e-06
+Pre-endocrine,Rbfox3,Phactr1,-0.26088367724777595,1.1475340930226109e-10,stabilizing,4.415425299104302e-10
+Pre-endocrine,Rbfox3,Exoc6b,0.2111980555844332,2.1437102502346326e-07,destabilizing,5.332898877541189e-07
+Pre-endocrine,Rbfox3,Grik2,0.2238460524254516,3.69372480043721e-08,destabilizing,1.0294290671895183e-07
+Pre-endocrine,Rbfox3,Plcb1,-0.2020830554631203,7.131789285130501e-07,stabilizing,1.6660818666103187e-06
+Pre-endocrine,Rbfox3,Cacna2d1,0.33340213515086753,7.781707602586095e-17,destabilizing,8.163451749128054e-16
+Pre-endocrine,Rbfox3,Shank2,-0.23004471783958452,1.5005296687509544e-08,stabilizing,4.340634291897225e-08
+Pre-endocrine,Rbfox3,Megf11,0.38351676732115964,3.5121336391614235e-22,destabilizing,6.974093940620541e-21
+Pre-endocrine,Rbfox3,Nol4,0.22537251910825995,2.9659614962209435e-08,destabilizing,8.32865955504467e-08
+Pre-endocrine,Rbfox3,Gabbr2,0.3124882715431422,7.091654520562406e-15,destabilizing,5.476333213100969e-14
+Pre-endocrine,Rbfox3,Kif24,0.21877541250937446,7.571349249699848e-08,destabilizing,2.028756714618369e-07
+Pre-endocrine,Srsf3,Megf11,0.24288722281710234,2.136236668175067e-09,destabilizing,6.691535704255421e-09
+Pre-endocrine,Srsf3,Nol4,0.2083860932238801,3.12409610709264e-07,destabilizing,7.610670033336716e-07
+Pre-endocrine,Ybx1,Shank2,0.21786344554130857,8.598957810192205e-08,destabilizing,2.276676448793746e-07
diff --git a/output/gap_analysis/results/network/pancreas/rbp_hub_counts.csv b/output/gap_analysis/results/network/pancreas/rbp_hub_counts.csv
new file mode 100644
index 0000000000000000000000000000000000000000..8f3792b505b46b4178c6a00228c50d9ba98be93e
--- /dev/null
+++ b/output/gap_analysis/results/network/pancreas/rbp_hub_counts.csv
@@ -0,0 +1,31 @@
+rbp,0
+Hnrnpa1,166
+Ybx1,158
+Srsf3,144
+Rbfox3,70
+Hnrnpd,48
+Tra2b,47
+Elavl1,43
+Fus,32
+Srsf1,30
+Zfp36l1,30
+Hnrnpc,29
+Matr3,27
+Ptbp1,27
+Elavl4,24
+Msi1,21
+Mbnl1,16
+Stau2,15
+Hnrnpa2b1,12
+Mettl3,11
+Igf2bp1,11
+Nova1,11
+Tardbp,10
+Upf1,9
+Pum2,9
+Mbnl2,8
+Rbfox1,8
+Celf2,8
+Ptbp2,7
+Cpeb1,6
+Ago2,6
diff --git a/output/gap_analysis/results/velocity_comparison/dentate_gyrus/velocity_comparison.json b/output/gap_analysis/results/velocity_comparison/dentate_gyrus/velocity_comparison.json
new file mode 100644
index 0000000000000000000000000000000000000000..7ba855f8b3cdf3117efc05297ecb45e1ad221050
--- /dev/null
+++ b/output/gap_analysis/results/velocity_comparison/dentate_gyrus/velocity_comparison.json
@@ -0,0 +1,6 @@
+{
+ "n_shared_genes": 2000,
+ "n_cells_both_nonzero": 2930,
+ "magnitude_spearman_r": 0.13782999362972143,
+ "mean_cosine_similarity": -0.17028553783893585
+}
\ No newline at end of file
diff --git a/output/gap_analysis/results/velocity_comparison/pancreas/velocity_comparison.json b/output/gap_analysis/results/velocity_comparison/pancreas/velocity_comparison.json
new file mode 100644
index 0000000000000000000000000000000000000000..694e5fba6480e284d056a358f303dc1aaf09bfd5
--- /dev/null
+++ b/output/gap_analysis/results/velocity_comparison/pancreas/velocity_comparison.json
@@ -0,0 +1,6 @@
+{
+ "n_shared_genes": 2000,
+ "n_cells_both_nonzero": 3696,
+ "magnitude_spearman_r": -0.1751217852097305,
+ "mean_cosine_similarity": -0.05615566670894623
+}
\ No newline at end of file
diff --git a/output/halflife_ablation/figures/halflife_ablation.png b/output/halflife_ablation/figures/halflife_ablation.png
new file mode 100644
index 0000000000000000000000000000000000000000..2c28f241fd19eaba22c5566153cbecd36ec8a354
Binary files /dev/null and b/output/halflife_ablation/figures/halflife_ablation.png differ
diff --git a/output/halflife_ablation/results/halflife_ablation.csv b/output/halflife_ablation/results/halflife_ablation.csv
new file mode 100644
index 0000000000000000000000000000000000000000..2d71edad856fe7a11cb8dc222e1adabbf214b06a
--- /dev/null
+++ b/output/halflife_ablation/results/halflife_ablation.csv
@@ -0,0 +1,25 @@
+dataset,reference,method,spearman_r,p_value,n_genes
+pancreas,Mouse (Herzog),scPTR gamma,-0.11433607312013698,4.6900321366437115e-25,8126
+pancreas,Mouse (Herzog),Raw u/s ratio,-0.1090993194631804,6.044941866287911e-23,8126
+pancreas,Mouse (Herzog),Unspliced only,-0.07615305927047525,6.2560774688381485e-12,8126
+pancreas,Mouse (Herzog),Expression,0.3407649825899174,4.594629211390184e-220,8126
+pancreas,Human (Schofield),scPTR gamma,-0.1373562905985519,9.158385203239082e-33,7464
+pancreas,Human (Schofield),Raw u/s ratio,-0.13043679452021623,1.0997559482386076e-29,7464
+pancreas,Human (Schofield),Unspliced only,-0.11037145059159899,1.142683085771533e-21,7464
+pancreas,Human (Schofield),Expression,0.3651232471127368,3.6571617165585257e-234,7464
+dentate_gyrus,Mouse (Herzog),scPTR gamma,-0.02573636524452943,0.11689014044910478,3713
+dentate_gyrus,Mouse (Herzog),Raw u/s ratio,-0.02068888376919076,0.20753413512053687,3713
+dentate_gyrus,Mouse (Herzog),Unspliced only,-0.03843746622886522,0.019168359008381815,3713
+dentate_gyrus,Mouse (Herzog),Expression,0.2913060773569477,1.5572859036569224e-73,3713
+dentate_gyrus,Human (Schofield),scPTR gamma,-0.05946761237657294,0.0004928608449730351,3430
+dentate_gyrus,Human (Schofield),Raw u/s ratio,-0.05466717804447504,0.0013606203124514103,3430
+dentate_gyrus,Human (Schofield),Unspliced only,-0.08789823540640025,2.523198086383909e-07,3430
+dentate_gyrus,Human (Schofield),Expression,0.3074640255934953,5.298407183938887e-76,3430
+scifate,Mouse (Herzog),scPTR gamma,-0.6747339653606712,0.0,6841
+scifate,Mouse (Herzog),Raw u/s ratio,-0.6682208414232903,0.0,6841
+scifate,Mouse (Herzog),Unspliced only,-0.2745074349578032,1.576780682941455e-118,6841
+scifate,Mouse (Herzog),Expression,0.26331840120613076,7.072041538092432e-109,6841
+scifate,Human (Schofield),scPTR gamma,-0.8132820679070741,0.0,7019
+scifate,Human (Schofield),Raw u/s ratio,-0.8092466597371252,0.0,7019
+scifate,Human (Schofield),Unspliced only,-0.34191035958075067,1.036341420828488e-191,7019
+scifate,Human (Schofield),Expression,0.3068355321366041,6.708558499627584e-153,7019
diff --git a/output/perturbation_validation/results/perturbation_validation.csv b/output/perturbation_validation/results/perturbation_validation.csv
new file mode 100644
index 0000000000000000000000000000000000000000..1c0dc5642580f0d56a52a54830528ce01ababd64
--- /dev/null
+++ b/output/perturbation_validation/results/perturbation_validation.csv
@@ -0,0 +1,12 @@
+rbp,dataset,validation,n_predicted_targets,n_predicted_destab,n_predicted_stab,n_perturbation_up,n_perturbation_down,overlap_destab_up,fisher_or,fisher_p,fdr
+ELAVL1,pancreas,Perturb-seq_CRISPRi,200,61,139,5,2,0,0.0,1.0,1.0
+FUS,pancreas,Perturb-seq_CRISPRi,200,88,112,1,1,0,0.0,1.0,1.0
+HNRNPA1,pancreas,Perturb-seq_CRISPRi,200,37,163,5,2,0,0.0,1.0,1.0
+HNRNPC,pancreas,Perturb-seq_CRISPRi,200,101,99,72,16,1,1.6581690140845071,0.4583908973556018,1.0
+MBNL1,pancreas,Perturb-seq_CRISPRi,200,121,79,39,18,0,0.0,1.0,1.0
+RBFOX2,pancreas,Perturb-seq_CRISPRi,200,59,141,59,0,0,0.0,1.0,1.0
+ELAVL1,dentate_gyrus,Perturb-seq_CRISPRi,200,79,121,5,2,0,0.0,1.0,1.0
+HNRNPA1,dentate_gyrus,Perturb-seq_CRISPRi,200,169,31,5,2,0,0.0,1.0,1.0
+HNRNPC,dentate_gyrus,Perturb-seq_CRISPRi,200,138,62,72,16,1,0.531715842500257,0.8478978582428542,1.0
+MBNL1,dentate_gyrus,Perturb-seq_CRISPRi,200,82,118,39,18,0,0.0,1.0,1.0
+RBFOX2,dentate_gyrus,Perturb-seq_CRISPRi,200,148,52,59,0,1,0.6039174290405818,0.8103798170748624,1.0
diff --git a/output/precedence/figures/precedence_dentate_gyrus.png b/output/precedence/figures/precedence_dentate_gyrus.png
new file mode 100644
index 0000000000000000000000000000000000000000..70dd5d5aaf6c905be534013af8c664be72148f59
Binary files /dev/null and b/output/precedence/figures/precedence_dentate_gyrus.png differ
diff --git a/output/precedence/figures/precedence_pancreas.png b/output/precedence/figures/precedence_pancreas.png
new file mode 100644
index 0000000000000000000000000000000000000000..c1cfdbd8fed84fb89cbc492cbce8e221b5488d72
Binary files /dev/null and b/output/precedence/figures/precedence_pancreas.png differ
diff --git a/output/precedence/results/combined_precedence.json b/output/precedence/results/combined_precedence.json
new file mode 100644
index 0000000000000000000000000000000000000000..7ef1e9d4fad127aa164a36e9deec8cd24a59adfb
--- /dev/null
+++ b/output/precedence/results/combined_precedence.json
@@ -0,0 +1,24 @@
+{
+ "pancreas": {
+ "n_transition_genes": 188,
+ "onset_gamma_leads": 119,
+ "onset_expr_leads": 58,
+ "onset_simultaneous": 11,
+ "onset_mean_lead_bins": 8.191489361702128,
+ "onset_binomial_p": 5.294914244749984e-06,
+ "crosscorr_mean_lag": 2.265957446808511,
+ "crosscorr_median_lag": 4.0,
+ "crosscorr_positive_lag_frac": 0.5531914893617021
+ },
+ "dentate_gyrus": {
+ "n_transition_genes": 146,
+ "onset_gamma_leads": 114,
+ "onset_expr_leads": 30,
+ "onset_simultaneous": 2,
+ "onset_mean_lead_bins": 23.65068493150685,
+ "onset_binomial_p": 9.932297501152282e-13,
+ "crosscorr_mean_lag": 2.089041095890411,
+ "crosscorr_median_lag": 3.0,
+ "crosscorr_positive_lag_frac": 0.5547945205479452
+ }
+}
\ No newline at end of file
diff --git a/output/precedence/results/pancreas/onset_detection.csv b/output/precedence/results/pancreas/onset_detection.csv
new file mode 100644
index 0000000000000000000000000000000000000000..00ed55dda5396034c444cae78b8a4d9d3832f323
--- /dev/null
+++ b/output/precedence/results/pancreas/onset_detection.csv
@@ -0,0 +1,189 @@
+gene,gamma_onset_bin,expr_onset_bin,lead_bins
+Fam135a,5,8,3
+Fam168b,14,6,-8
+Fhl2,0,28,28
+Ankrd44,6,56,50
+Tns1,6,12,6
+Sphkap,59,67,8
+Dner,18,35,17
+Pam,15,63,48
+Bcl2,0,11,11
+Tmem163,49,62,13
+Nr5a2,7,7,0
+Lamc1,9,7,-2
+St18,39,49,10
+Kcnb2,12,21,9
+Dst,4,19,15
+Sdccag8,5,10,5
+Cnksr3,5,12,7
+Utrn,5,4,-1
+Adgrg6,10,10,0
+Slc16a10,5,68,63
+Arid5b,12,13,1
+Bicc1,9,12,3
+Rassf3,6,9,3
+Rfx6,10,15,5
+Dcbld1,5,0,-5
+Spock2,10,22,12
+Pbld2,5,12,7
+Tspear,11,11,0
+Gns,15,14,-1
+Gck,11,27,16
+Grb10,11,8,-3
+Meis1,6,4,-2
+Acyp2,0,14,14
+Wwc1,10,13,3
+Rap1gap2,6,10,4
+Msi2,6,4,-2
+Stat3,0,12,12
+2610035D17Rik,14,7,-7
+Rbfox3,11,17,6
+P4hb,12,6,-6
+Ccnjl,7,15,8
+Hnf1b,8,11,3
+Stxbp6,5,4,-1
+Sel1l,0,8,8
+Mboat2,14,8,-6
+Flrt2,5,0,-5
+Meg3,6,6,0
+Ptprn2,26,19,-7
+Ror2,5,10,5
+Ptch1,0,8,8
+Cdc14b,7,15,8
+Adamts16,11,11,0
+Snrnp48,8,5,-3
+Jarid2,0,19,19
+Cadps,14,37,23
+Kcnk16,13,24,11
+Sema3g,12,15,3
+Gm8113,5,10,5
+Ghr,0,63,63
+Tcf20,5,11,6
+Plcxd3,16,18,2
+Ank,9,62,53
+Cpq,5,6,1
+Khdrbs3,11,47,36
+Igf2bp2,10,5,-5
+Phldb2,12,7,-5
+Alcam,11,9,-2
+Vps8,5,81,76
+Lpp,0,9,9
+Zfp148,16,4,-12
+Zbtb20,9,18,9
+Cxadr,5,0,-5
+Pacrg,0,12,12
+Baiap3,26,44,18
+Tcp11,13,30,17
+Mtch1,0,8,8
+Glo1,9,23,14
+Ptprs,13,0,-13
+Lrpprc,8,59,51
+Rnaset2b,5,0,-5
+Pde10a,47,57,10
+Epb41l3,5,6,1
+Atp8b1,11,7,-4
+Snx24,8,8,0
+Nedd4l,20,9,-11
+Tcf4,0,7,7
+Malat1,16,5,-11
+Slc16a12,6,14,8
+Gnaq,0,10,10
+Tcf7l2,9,12,3
+Celf2,0,5,5
+Atf2,9,13,4
+Nckap1,22,6,-16
+Cd82,5,10,5
+Meis2,11,7,-4
+Nkx2-2,4,17,13
+Lama5,12,0,-12
+Pkp4,6,0,-6
+Snap25,47,59,12
+Pcsk2,39,68,29
+Pygb,5,6,1
+Cbfa2t2,11,15,4
+Eya2,10,18,8
+Tshz2,10,7,-3
+Stx16,6,9,3
+Myt1,15,31,16
+Fndc3b,7,9,2
+Slc7a14,46,58,12
+Pex5l,35,45,10
+Nbea,8,8,0
+Riiad1,30,41,11
+5330417C22Rik,9,5,-4
+Kcnmb2,29,67,38
+Notch2,7,4,-3
+Vtcn1,12,12,0
+Sec24d,4,17,13
+Tspan5,8,23,15
+Klhl32,15,63,48
+B4galt1,5,5,0
+Fam219a,24,28,4
+Grin3a,7,10,3
+Nfib,16,5,-11
+Igsf21,24,42,18
+Park7,13,5,-8
+Runx1t1,25,45,20
+Tgfbr1,13,5,-8
+Dab1,12,6,-6
+Lrp8,11,28,17
+Phc2,24,9,-15
+Rere,10,4,-6
+Errfi1,11,0,-11
+Rbm47,19,5,-14
+Miat,14,28,14
+Tpcn1,18,11,-7
+Atp2a2,0,55,55
+Pitpnm2,10,13,3
+Rimbp2,43,49,6
+Auts2,7,6,-1
+Pclo,11,19,8
+Cacna2d1,16,25,9
+Dpysl5,17,30,13
+Ttc28,5,21,16
+Hnf1aos1,6,6,0
+Mlxipl,5,55,50
+Slc25a13,15,6,-9
+Ica1,7,9,2
+Hipk2,6,5,-1
+Dennd2a,4,11,7
+Foxp1,5,5,0
+Gng12,11,68,57
+Gipr,20,26,6
+Abcc8,15,16,1
+Rps3,36,6,-30
+Galnt18,5,79,74
+Fgfr2,15,10,-5
+Ctbp2,13,6,-7
+Ins2,6,81,75
+Nav2,5,0,-5
+Igf1r,12,5,-7
+Tenm4,5,14,9
+Stard10,8,10,2
+Spon1,6,0,-6
+Shank2,8,6,-2
+Rbpms,12,4,-8
+Nfix,0,10,10
+Rfwd3,6,5,-1
+Sorbs2,10,5,-5
+Tbc1d9,4,18,14
+Gnao1,38,55,17
+Vat1l,27,47,20
+Cmip,15,12,-3
+Gse1,11,12,1
+Pard3,7,9,2
+Dync2h1,13,17,4
+St3gal4,9,7,-2
+Ncam1,7,57,50
+Rbms3,0,5,5
+Megf11,13,22,9
+Igdcc4,5,11,6
+Rab27a,8,60,52
+Entpd3,6,69,63
+Dock11,4,11,7
+Ocrl,5,23,18
+Chic1,9,12,3
+Atg4a,12,19,7
+Map3k15,12,22,10
+Ap1s2,42,35,-7
+Gpm6b,12,7,-5
diff --git a/output/tier1_fixes/results/invisible_states/dentate_gyrus/OL_diff_degraded.csv b/output/tier1_fixes/results/invisible_states/dentate_gyrus/OL_diff_degraded.csv
new file mode 100644
index 0000000000000000000000000000000000000000..2eed6390d23b1bb61e3c5da7dfb591df1033e90c
--- /dev/null
+++ b/output/tier1_fixes/results/invisible_states/dentate_gyrus/OL_diff_degraded.csv
@@ -0,0 +1,1357 @@
+gene,p_value,log2_fc_gamma,medians,fdr
+Pnpla7,1.5039715835544759e-09,16.232727,"[np.float32(770.07355), np.float32(0.0)]",4.6898847213840405e-07
+Dapk1,0.010011123405162801,14.753886,"[np.float32(276.27823), np.float32(0.0)]",0.015779959470142883
+Palm2,1.826060029116717e-06,14.579544,"[np.float32(0.0), np.float32(244.82863)]",1.4246448482471459e-05
+Csmd3,9.29574587903479e-06,13.2750225,"[np.float32(99.11428), np.float32(0.0)]",4.85819568147321e-05
+Map4,0.0005764270294671107,13.042584,"[np.float32(84.36409), np.float32(0.0)]",0.0013265620813443595
+Erc2,0.0018734546786427003,12.785165,"[np.float32(0.0), np.float32(70.57593)]",0.0036742491653464276
+Pias1,6.06808531458681e-06,12.460472,"[np.float32(56.35062), np.float32(0.0)]",3.4933500380282835e-05
+Soga1,0.0006377253929767605,12.232117,"[np.float32(48.099842), np.float32(0.0)]",0.001439305440602556
+Nkain3,0.0008293401077747332,12.056653,"[np.float32(0.0), np.float32(42.590443)]",0.0018298294123190162
+Sfswap,0.0018168158442228668,12.033557,"[np.float32(0.0), np.float32(41.913883)]",0.0035857198782077893
+B3galt1,9.87338375454933e-06,11.896596,"[np.float32(0.0), np.float32(38.116962)]",4.963651573266607e-05
+Ppm1e,0.0005679715535481709,11.888971,"[np.float32(0.0), np.float32(37.915997)]",0.0013103264817369022
+Orc2,2.478128647427612e-06,11.631976,"[np.float32(0.0), np.float32(31.727568)]",1.7365463293397238e-05
+Ak5,2.4586486670205546e-06,11.624572,"[np.float32(0.0), np.float32(31.565111)]",1.7293728030058113e-05
+Fam19a5,0.0012523331991712492,11.416786,"[np.float32(27.329788), np.float32(0.0)]",0.0025663914738766782
+Tanc2,0.0008592463845050558,11.41428,"[np.float32(27.282328), np.float32(0.0)]",0.0018913529240105404
+Cadps,0.0006871921434905276,11.329008,"[np.float32(0.0), np.float32(25.715933)]",0.0015342917666715716
+Dgkh,7.028844241285732e-07,11.215158,"[np.float32(0.0), np.float32(23.76382)]",8.226817921184841e-06
+Spg11,0.00011332952782727725,11.187884,"[np.float32(0.0), np.float32(23.318602)]",0.0003333652993061461
+Cped1,3.6226297939257245e-05,11.182982,"[np.float32(0.0), np.float32(23.239483)]",0.00013316189281797701
+Itsn2,0.0007402670963974506,11.1683235,"[np.float32(23.00444), np.float32(0.0)]",0.001646896239428811
+Ints4,0.0015817715219300233,11.130844,"[np.float32(22.414255), np.float32(0.0)]",0.003158478673992608
+Pibf1,2.7936014482776335e-07,11.033447,"[np.float32(0.0), np.float32(20.950357)]",4.505886473902976e-06
+Dscam,0.001221418750031809,11.020444,"[np.float32(0.0), np.float32(20.76228)]",0.002511290638801664
+Rgma,3.5226853966390725e-06,11.011913,"[np.float32(20.639814), np.float32(0.0)]",2.2885223531637866e-05
+Letm2,1.9241575423763015e-08,11.0007515,"[np.float32(0.0), np.float32(20.480673)]",1.0770375890496962e-06
+Grb10,0.00018547702385230067,11.000588,"[np.float32(0.0), np.float32(20.478352)]",0.0005187257273955973
+Mob3b,9.940766579397739e-08,10.963482,"[np.float32(19.95811), np.float32(0.0)]",2.2141874131015676e-06
+Gatad2b,1.46094853022099e-08,10.905991,"[np.float32(19.178026), np.float32(0.0)]",9.762266785869543e-07
+Slc9a9,0.000684416422653107,10.885717,"[np.float32(18.91028), np.float32(0.0)]",0.0015317501516554585
+Syt1,0.0001123352240009654,10.838319,"[np.float32(0.0), np.float32(18.298763)]",0.0003320366573551442
+Timmdc1,9.602695348114541e-07,10.812362,"[np.float32(17.972294), np.float32(0.0)]",9.469920567261343e-06
+Dclk1,7.996671406076568e-06,10.767252,"[np.float32(0.0), np.float32(17.418734)]",4.381569192791318e-05
+Smarcad1,0.001072837777646987,10.748822,"[np.float32(17.197502), np.float32(0.0)]",0.0022303105355305696
+Gfod1,0.010278581260895672,10.745109,"[np.float32(0.0), np.float32(17.15327)]",0.016169741412747622
+Tra2a,0.0006871921434905276,10.716536,"[np.float32(0.0), np.float32(16.81669)]",0.0015342917666715716
+2010111I01Rik,4.44685136935567e-06,10.664811,"[np.float32(16.224096), np.float32(0.0)]",2.7013178285923568e-05
+Hecw1,0.0002857821530036944,10.572877,"[np.float32(0.0), np.float32(15.22186)]",0.0007509809104914498
+Tubgcp5,0.01068232575535495,10.544943,"[np.float32(14.929772), np.float32(0.0)]",0.016753253552614512
+Ccdc117,0.0004325096381211812,10.454374,"[np.float32(14.020729), np.float32(0.0)]",0.0010414743023484298
+Kcnma1,8.069156747153875e-06,10.433673,"[np.float32(0.0), np.float32(13.820837)]",4.4015720915232944e-05
+Anks3,0.0085012353988115,10.416028,"[np.float32(0.0), np.float32(13.65271)]",0.013688305878809223
+Rnf103,1.8806293069448252e-05,10.32982,"[np.float32(12.860203), np.float32(0.0)]",8.315707294872946e-05
+Gtf3c1,0.0037781757720286076,10.3296795,"[np.float32(12.858956), np.float32(0.0)]",0.006588039952903565
+Zfp74,8.625015599832392e-07,10.303917,"[np.float32(0.0), np.float32(12.631195)]",9.143789720740064e-06
+Pigu,1.596137820744021e-06,10.273275,"[np.float32(12.36554), np.float32(0.0)]",1.3278801064567333e-05
+Irf2,7.743242350666123e-05,10.160831,"[np.float32(11.437614), np.float32(0.0)]",0.00024892794567175805
+Fam19a2,7.299986080413111e-05,10.133411,"[np.float32(0.0), np.float32(11.222095)]",0.0002367118536646955
+Ankrd44,5.823778723230174e-07,10.131124,"[np.float32(0.0), np.float32(11.2043)]",7.3623581021376054e-06
+Psd3,1.2121154653512045e-06,10.121378,"[np.float32(0.0), np.float32(11.128799)]",1.10090681343306e-05
+Fbxw4,7.496192576887902e-08,10.117128,"[np.float32(11.096039), np.float32(0.0)]",1.9479689321329535e-06
+Osbpl8,0.00018293570530224606,10.111943,"[np.float32(11.056194), np.float32(0.0)]",0.0005131524806904084
+Ctnnd2,4.6183020241659404e-08,10.071962,"[np.float32(10.753728), np.float32(0.0)]",1.489335903757613e-06
+Cbll1,3.758314299755403e-05,10.056327,"[np.float32(10.637702), np.float32(0.0)]",0.00013470892825368503
+Pten,0.00018173233868887985,9.994566,"[np.float32(0.0), np.float32(10.191502)]",0.0005105423508812225
+Ppm1b,3.716104710935647e-05,9.985329,"[np.float32(10.126391), np.float32(0.0)]",0.00013470892825368503
+Cpsf6,4.2437299240932474e-07,9.980726,"[np.float32(0.0), np.float32(10.094106)]",5.969938863141704e-06
+Ryr2,0.00010135212935844583,9.980418,"[np.float32(0.0), np.float32(10.091951)]",0.0003149291771765997
+Ints3,0.00012593463176940612,9.973639,"[np.float32(0.0), np.float32(10.044591)]",0.0003665152634795504
+Mynn,1.005399954300246e-06,9.972234,"[np.float32(10.034806), np.float32(0.0)]",9.746649297905494e-06
+Irs2,7.248469289986006e-06,9.925863,"[np.float32(0.0), np.float32(9.717078)]",4.060444922623897e-05
+Arhgap31,0.00012709947874027467,9.917753,"[np.float32(0.0), np.float32(9.662553)]",0.0003675473334204852
+Nrcam,0.0009102254372184114,9.915179,"[np.float32(0.0), np.float32(9.645313)]",0.001991850050334091
+Dgkb,3.992906310534964e-05,9.913569,"[np.float32(0.0), np.float32(9.634548)]",0.00014149105505702496
+Gemin5,9.839972845780528e-05,9.909095,"[np.float32(9.604676), np.float32(0.0)]",0.00030786938452266507
+Gbf1,1.289574495453319e-05,9.895701,"[np.float32(9.515832), np.float32(0.0)]",6.186650976905537e-05
+Rapgef4,7.836921367198055e-10,9.894102,"[np.float32(0.0), np.float32(9.505276)]",4.1043809418180814e-07
+Ptchd4,3.542451371557169e-05,9.8680935,"[np.float32(0.0), np.float32(9.335273)]",0.00013072833365253378
+Aldh6a1,4.12189477344174e-05,9.866359,"[np.float32(9.324048), np.float32(0.0)]",0.00014551066266244332
+Eif3j1,0.02460180269137669,9.863339,"[np.float32(9.304532), np.float32(0.0)]",0.035326149528446496
+Pstk,0.0006333415405425226,9.859941,"[np.float32(9.28261), np.float32(0.0)]",0.0014311377081582847
+Sfi1,0.0008248136168575374,9.8396015,"[np.float32(9.152524), np.float32(0.0)]",0.001821990882102069
+Cdh9,0.00011551600328303428,9.837991,"[np.float32(0.0), np.float32(9.142303)]",0.00033823230382246816
+Tenm1,1.1434850140102618e-06,9.830887,"[np.float32(0.0), np.float32(9.0973425)]",1.0644081896583084e-05
+Ccdc47,5.5435587766889494e-08,9.795977,"[np.float32(0.0), np.float32(8.879613)]",1.6463489636801627e-06
+Lats1,4.5425278265804326e-05,9.7842245,"[np.float32(8.807493), np.float32(0.0)]",0.00015826945183486013
+Fer,0.00019639036623808192,9.774208,"[np.float32(8.746487), np.float32(0.0)]",0.0005427568319519221
+Metap1d,7.205420390418118e-05,9.760623,"[np.float32(8.664416), np.float32(0.0)]",0.00023660165890359512
+Snx18,8.30152535831948e-06,9.658292,"[np.float32(0.0), np.float32(8.070448)]",4.5052798348645617e-05
+Anapc10,1.8708783931325695e-05,9.6510315,"[np.float32(0.0), np.float32(8.029888)]",8.31452131484807e-05
+Camta1,1.0021335047931586e-08,9.628131,"[np.float32(0.0), np.float32(7.9032717)]",7.896715598504087e-07
+4833420G17Rik,8.21021565561035e-08,9.605416,"[np.float32(7.7796597), np.float32(0.0)]",1.981202178615355e-06
+Cstf3,0.00018953601553258208,9.5581875,"[np.float32(7.528782), np.float32(0.0)]",0.0005269270208937014
+E430025E21Rik,0.008695975160854711,9.535949,"[np.float32(7.4134636), np.float32(0.0)]",0.013929939662636273
+Hdac8,1.4435379546776395e-05,9.532204,"[np.float32(0.0), np.float32(7.3942184)]",6.685295824757087e-05
+Gopc,1.8182598541767992e-06,9.514711,"[np.float32(7.304987), np.float32(0.0)]",1.4246448482471459e-05
+Srgap2,0.003319779079063784,9.49963,"[np.float32(7.228914), np.float32(0.0)]",0.00585420043065819
+Akap10,8.922214981557997e-06,9.487208,"[np.float32(0.0), np.float32(7.1668553)]",4.785874006407393e-05
+Snx29,0.007245183667865065,9.48236,"[np.float32(0.0), np.float32(7.1427784)]",0.011849421890363232
+Shisa9,0.00014348097393548204,9.439392,"[np.float32(0.0), np.float32(6.932889)]",0.0004104784437817842
+Prcp,8.093416019256985e-07,9.4190235,"[np.float32(0.0), np.float32(6.835555)]",8.80394265815687e-06
+Ccdc66,0.0005901120748693048,9.37184,"[np.float32(6.6152864), np.float32(0.0)]",0.001354723548564993
+Klf10,9.87338375454933e-06,9.351819,"[np.float32(0.0), np.float32(6.523984)]",4.963651573266607e-05
+Cnppd1,1.8570597474347821e-07,9.334285,"[np.float32(0.0), np.float32(6.44505)]",3.4064301837749776e-06
+Optn,2.817475250242235e-06,9.319221,"[np.float32(6.378), np.float32(0.0)]",1.903067217762896e-05
+Col25a1,0.00012933645478844938,9.283291,"[np.float32(0.0), np.float32(6.220876)]",0.00037286364700953587
+Ube3a,1.4401011138294954e-05,9.271534,"[np.float32(0.0), np.float32(6.1703033)]",6.685295824757087e-05
+Tbc1d22a,2.3423806209780776e-06,9.265132,"[np.float32(0.0), np.float32(6.1429386)]",1.673198488840427e-05
+1810013L24Rik,1.2570366420398164e-05,9.253074,"[np.float32(0.0), np.float32(6.091726)]",6.0616380341662276e-05
+Shank2,9.87338375454933e-06,9.21837,"[np.float32(0.0), np.float32(5.946705)]",4.963651573266607e-05
+Atg13,1.0761803980741857e-06,9.213458,"[np.float32(5.9264565), np.float32(0.0)]",1.0186902498551097e-05
+Lzic,1.409040946631403e-05,9.204738,"[np.float32(5.890679), np.float32(0.0)]",6.623908570721998e-05
+Stat2,2.5665053112198856e-05,9.200904,"[np.float32(5.8750205), np.float32(0.0)]",0.00010864098274417208
+Xrn1,4.44685136935567e-06,9.196158,"[np.float32(5.855694), np.float32(0.0)]",2.7013178285923568e-05
+Sirt5,1.7965582489922722e-05,9.171084,"[np.float32(5.754632), np.float32(0.0)]",8.099663816541063e-05
+Srpk1,1.27781010649948e-06,9.165193,"[np.float32(0.0), np.float32(5.731138)]",1.149414764067561e-05
+Senp2,0.0018734546786427003,9.140929,"[np.float32(0.0), np.float32(5.6353903)]",0.0036742491653464276
+Fam135a,1.0705045313028791e-05,9.135594,"[np.float32(0.0), np.float32(5.61455)]",5.298714227692293e-05
+Grid2,7.283942037865888e-05,9.110117,"[np.float32(5.5160966), np.float32(0.0)]",0.00023660165890359512
+Sec24b,9.29574587903479e-06,9.109288,"[np.float32(5.5129247), np.float32(0.0)]",4.85819568147321e-05
+Rhobtb3,3.6818934974038055e-06,9.1046915,"[np.float32(5.495355), np.float32(0.0)]",2.375456115049145e-05
+Chd9,0.0006289234305739688,9.093339,"[np.float32(5.4522023), np.float32(0.0)]",0.0014300762104511777
+Fkbp15,0.00026924381243458696,9.090153,"[np.float32(0.0), np.float32(5.440152)]",0.0007175999616312139
+Wdr73,5.93583900632108e-09,9.0878315,"[np.float32(5.4313912), np.float32(0.0)]",6.941221738016714e-07
+Senp1,5.249361791172059e-05,9.082101,"[np.float32(0.0), np.float32(5.4098177)]",0.00017922547283362998
+Gnai3,6.80281290428268e-06,9.064367,"[np.float32(0.0), np.float32(5.3436065)]",3.863652588689057e-05
+Edem1,0.022751560174290524,9.04755,"[np.float32(5.2815614), np.float32(0.0)]",0.03284580948001355
+Crebrf,0.000258805955579979,9.027333,"[np.float32(5.207928), np.float32(0.0)]",0.0006937334425360181
+Bckdhb,0.00139900912696904,8.991354,"[np.float32(5.079409), np.float32(0.0)]",0.0028195043897252187
+Cnksr3,0.0001847666293834639,8.97548,"[np.float32(5.0237174), np.float32(0.0)]",0.0005175125203240433
+Pacrg,0.0003713294486387527,8.97313,"[np.float32(5.0155225), np.float32(0.0)]",0.0009141544715830346
+A430105J06Rik,6.845015760970606e-05,8.915364,"[np.float32(4.818275), np.float32(0.0)]",0.00022788299802092534
+Cndp2,1.0968415130459865e-09,8.903359,"[np.float32(4.778265), np.float32(0.0)]",4.1043809418180814e-07
+Parp16,0.00014309806272627662,8.853806,"[np.float32(0.0), np.float32(4.6165886)]",0.0004100099163259779
+Sec24d,7.455740642684681e-07,8.851672,"[np.float32(4.609755), np.float32(0.0)]",8.47352854761284e-06
+Zfp612,6.147629273907326e-05,8.844357,"[np.float32(0.0), np.float32(4.5863867)]",0.0002076211980411662
+Nudt13,4.769778242795086e-07,8.838594,"[np.float32(4.568065), np.float32(0.0)]",6.466851516137395e-06
+Mtif2,7.280000466982585e-05,8.834959,"[np.float32(4.556545), np.float32(0.0)]",0.00023660165890359512
+Kdm3a,6.047851844770112e-07,8.8305025,"[np.float32(4.54246), np.float32(0.0)]",7.594315974204618e-06
+Asb3,0.00022852842769051056,8.810735,"[np.float32(4.480507), np.float32(0.0)]",0.0006232896329576461
+Onecut2,7.552041120492522e-06,8.810323,"[np.float32(4.479226), np.float32(0.0)]",4.192839447015284e-05
+Dopey1,1.5208158265184192e-05,8.807217,"[np.float32(4.46957), np.float32(0.0)]",6.991268824117843e-05
+Kcmf1,1.812884873557543e-05,8.796648,"[np.float32(4.436874), np.float32(0.0)]",8.153624034678276e-05
+Ccdc50,0.01821277786979566,8.781798,"[np.float32(0.0), np.float32(4.3913374)]",0.02706601063890999
+Uck2,0.00028061432571445497,8.781515,"[np.float32(0.0), np.float32(4.390475)]",0.0007415669539713915
+Iah1,0.0001022675663824141,8.743096,"[np.float32(0.0), np.float32(4.274835)]",0.00031626878793635833
+Gm26910,0.0020621443241353133,8.739937,"[np.float32(0.0), np.float32(4.265463)]",0.003977600031399146
+C2cd5,2.310451559146736e-06,8.733093,"[np.float32(0.0), np.float32(4.2452307)]",1.6626364873705936e-05
+Zswim7,2.0203628967901412e-05,8.665316,"[np.float32(0.0), np.float32(4.049944)]",8.811419533553273e-05
+Tti2,0.00011391977703234123,8.657148,"[np.float32(4.0270247), np.float32(0.0)]",0.00033408135239421696
+Trmt10b,0.000414887750031,8.65523,"[np.float32(4.0216594), np.float32(0.0)]",0.0010068157980648521
+Dock6,2.3850720587696555e-06,8.645715,"[np.float32(0.0), np.float32(3.9951575)]",1.6903294780144038e-05
+St3gal4,3.487835180997234e-05,8.640139,"[np.float32(3.9797053), np.float32(0.0)]",0.00012999481322003637
+AA543186,9.270070114084299e-05,8.627975,"[np.float32(3.9462113), np.float32(0.0)]",0.00029150086022607937
+Ksr1,2.6289583347612748e-08,8.607156,"[np.float32(0.0), np.float32(3.8895278)]",1.1774116340731756e-06
+Tpk1,3.88985103960996e-07,8.599602,"[np.float32(0.0), np.float32(3.869162)]",5.641791701635842e-06
+Eml5,3.992906310534964e-05,8.570895,"[np.float32(0.0), np.float32(3.7927396)]",0.00014149105505702496
+Polr3c,7.784109518401486e-05,8.5698185,"[np.float32(3.789902), np.float32(0.0)]",0.00024981250272605797
+Ensa,0.022048823617963457,8.541414,"[np.float32(3.715819), np.float32(0.0)]",0.03202899766242983
+Clstn2,0.0005498193834933273,8.539336,"[np.float32(0.0), np.float32(3.7104583)]",0.0012747361419033648
+Actn1,0.00019846148734673866,8.539086,"[np.float32(0.0), np.float32(3.7098126)]",0.0005468651588008071
+Ncoa2,0.02182015111262247,8.51346,"[np.float32(3.644323), np.float32(0.0)]",0.031721447343991176
+Med14,0.0017113656285061638,8.510287,"[np.float32(0.0), np.float32(3.636294)]",0.0033955091102174256
+3110052M02Rik,0.02074848816143493,8.503352,"[np.float32(3.6188076), np.float32(0.0)]",0.030471288343834186
+Gm12089,0.0005247359392214896,8.497912,"[np.float32(3.6051528), np.float32(0.0)]",0.0012241657634456445
+Rev3l,0.00039467599285874356,8.484643,"[np.float32(3.5720544), np.float32(0.0)]",0.0009627624284728934
+Ubac2,1.397323428922309e-07,8.483145,"[np.float32(3.5683346), np.float32(0.0)]",2.78126822926983e-06
+Mettl16,6.925639616797046e-08,8.471262,"[np.float32(3.5389836), np.float32(0.0)]",1.8511245318610392e-06
+Trio,1.3946792851898865e-05,8.464907,"[np.float32(0.0), np.float32(3.523384)]",6.576119877273319e-05
+Flrt3,0.00010633252698454759,8.462056,"[np.float32(0.0), np.float32(3.5164092)]",0.0003257979454786641
+Styx,6.341654280711505e-07,8.4527025,"[np.float32(3.4936194), np.float32(0.0)]",7.806075762638965e-06
+Cox10,0.004834987332862763,8.430801,"[np.float32(0.0), np.float32(3.4408348)]",0.008157133723882985
+Clcc1,7.767452659770678e-09,8.430303,"[np.float32(0.0), np.float32(3.4396415)]",7.189633497653282e-07
+B630005N14Rik,8.979154691179094e-08,8.41457,"[np.float32(0.0), np.float32(3.4022274)]",2.074073879900751e-06
+Ptbp2,7.412275142813438e-05,8.375995,"[np.float32(3.3121998), np.float32(0.0)]",0.00023952274252511126
+Dlgap1,0.0006249418647299054,8.370577,"[np.float32(0.0), np.float32(3.299746)]",0.0014241975991591388
+Ccnb2,3.527831755523811e-05,8.367255,"[np.float32(3.2921348), np.float32(0.0)]",0.00013070442009079309
+Rab11fip2,1.4435379546776395e-05,8.366194,"[np.float32(3.289707), np.float32(0.0)]",6.685295824757087e-05
+Tjp2,1.4413568489886897e-06,8.342302,"[np.float32(3.235513), np.float32(0.0)]",1.2427551449114462e-05
+Ctps2,3.181736669130244e-05,8.3413,"[np.float32(3.233259), np.float32(0.0)]",0.00012613985252110196
+R3hdm1,0.0031086476973195033,8.331645,"[np.float32(3.211626), np.float32(0.0)]",0.005533002174311384
+Erlec1,0.00028475163138526837,8.328688,"[np.float32(3.205029), np.float32(0.0)]",0.0007493253197212899
+Vps4b,2.9576647479447225e-07,8.316836,"[np.float32(3.1787257), np.float32(0.0)]",4.674480232836159e-06
+Irf9,0.006495635841543752,8.301044,"[np.float32(3.1440127), np.float32(0.0)]",0.01077423285419181
+Tfam,3.1228744171477383e-05,8.281394,"[np.float32(0.0), np.float32(3.1013446)]",0.00012613985252110196
+Zfp213,0.011265803061550726,8.280073,"[np.float32(0.0), np.float32(3.0984967)]",0.017594588921670623
+Zfx,0.013557408666923442,8.278738,"[np.float32(3.0956216), np.float32(0.0)]",0.02074072903991313
+Lrig2,0.0014900952078806965,8.278073,"[np.float32(3.094191), np.float32(0.0)]",0.002981784100475704
+Pik3c2b,1.49310684382452e-06,8.272716,"[np.float32(3.0826843), np.float32(0.0)]",1.2640737125772292e-05
+Erich1,0.0024418982897663664,8.26882,"[np.float32(0.0), np.float32(3.074343)]",0.004614941111265526
+Stt3b,0.03498697462637035,8.263439,"[np.float32(3.0628626), np.float32(0.0)]",0.04838184000438945
+Tti1,2.6236358800009723e-06,8.245866,"[np.float32(0.0), np.float32(3.025658)]",1.8222018969009912e-05
+Rsph3b,0.0003484988826125715,8.23066,"[np.float32(2.993832), np.float32(0.0)]",0.0008634823203219308
+Enox2,0.0007335885472381331,8.229367,"[np.float32(0.0), np.float32(2.991141)]",0.0016339811570030322
+Nmnat2,0.0005966452616306903,8.213423,"[np.float32(0.0), np.float32(2.9581547)]",0.0013680432408223304
+Eed,0.00033976184246870596,8.1933155,"[np.float32(2.9170735), np.float32(0.0)]",0.0008634823203219308
+Abca7,0.004724578673174747,8.183681,"[np.float32(0.0), np.float32(2.8975906)]",0.007992483451636483
+4932438A13Rik,8.729650874831397e-06,8.1626425,"[np.float32(0.0), np.float32(2.855499)]",4.706967373720329e-05
+Fra10ac1,2.6239853324079763e-05,8.150479,"[np.float32(0.0), np.float32(2.8314416)]",0.00011057379632737215
+Cttnbp2,0.0002838626853711976,8.146741,"[np.float32(2.8240874), np.float32(0.0)]",0.0007480381469429727
+Capza1,0.00018953601553258208,8.134049,"[np.float32(2.7992651), np.float32(0.0)]",0.0005269270208937014
+Cmc1,1.8844977267802064e-05,8.126143,"[np.float32(2.783914), np.float32(0.0)]",8.315707294872946e-05
+Larp4,0.017629823620491553,8.122712,"[np.float32(2.7772765), np.float32(0.0)]",0.02641303520935637
+Gemin6,2.894758694140357e-08,8.082457,"[np.float32(2.700578), np.float32(0.0)]",1.1774116340731756e-06
+Sart1,1.0280475467360912e-05,8.06227,"[np.float32(0.0), np.float32(2.6629152)]",5.115630212614964e-05
+Nrp1,9.53064241054157e-06,8.062033,"[np.float32(0.0), np.float32(2.6624756)]",4.9427727555783e-05
+Nol11,3.4046700153308966e-10,8.015533,"[np.float32(2.5777125), np.float32(0.0)]",4.1043809418180814e-07
+Ikzf2,2.8022517756576057e-05,8.015177,"[np.float32(0.0), np.float32(2.5770729)]",0.00011703154179141474
+Syt16,0.00010354408305441785,8.004205,"[np.float32(0.0), np.float32(2.5574727)]",0.00031863647926778915
+Extl3,2.1596320578865566e-07,7.9912314,"[np.float32(0.0), np.float32(2.534488)]",3.7763285797249973e-06
+Sbf2,1.997442810493586e-07,7.9908285,"[np.float32(2.5337768), np.float32(0.0)]",3.5821005048050626e-06
+Rasgrf1,0.0002785041499008864,7.981603,"[np.float32(0.0), np.float32(2.5175626)]",0.0007380754454172216
+Unc45a,5.5311475141154834e-05,7.974244,"[np.float32(2.5047028), np.float32(0.0)]",0.00018781809435408474
+Dram2,3.342990787756362e-05,7.96762,"[np.float32(2.4931827), np.float32(0.0)]",0.00012613985252110196
+Echdc1,2.0131531934466397e-07,7.9611526,"[np.float32(0.0), np.float32(2.481987)]",3.5821005048050626e-06
+Nagk,0.015899619723150387,7.951109,"[np.float32(2.4646986), np.float32(0.0)]",0.023940327111545503
+Ocrl,8.468217868959695e-05,7.9459147,"[np.float32(2.4558048), np.float32(0.0)]",0.0002685429768275185
+Vcpip1,9.29574587903479e-06,7.939582,"[np.float32(2.4450042), np.float32(0.0)]",4.85819568147321e-05
+Ldlr,0.006467147002971467,7.9395413,"[np.float32(0.0), np.float32(2.4449353)]",0.01073649693217357
+Bbs5,0.00019685679816603522,7.91316,"[np.float32(0.0), np.float32(2.4004517)]",0.0005432434651455043
+Fbrsl1,7.18853066965661e-06,7.9117823,"[np.float32(2.3981512), np.float32(0.0)]",4.038961226104359e-05
+Igf2bp3,0.0002991487512844372,7.8938704,"[np.float32(0.0), np.float32(2.3684375)]",0.0007806238684144799
+Morn1,0.0040227368760927,7.893685,"[np.float32(0.0), np.float32(2.368132)]",0.006911423962506375
+Ly6e,0.0002584163051139118,7.8780394,"[np.float32(0.0), np.float32(2.3424814)]",0.000693682793211089
+Mical3,0.010278581260895672,7.8489585,"[np.float32(2.2955363), np.float32(0.0)]",0.016169741412747622
+Srr,0.035427966643677124,7.8348002,"[np.float32(2.2730207), np.float32(0.0)]",0.04895548418782858
+Man1a2,0.006317228088103253,7.8340316,"[np.float32(0.0), np.float32(2.2718048)]",0.010506252224747723
+Iars,9.366271591737762e-07,7.8187165,"[np.float32(2.24771), np.float32(0.0)]",9.469920567261343e-06
+Meaf6,0.0015838974690479978,7.7889347,"[np.float32(0.0), np.float32(2.2015817)]",0.003159351987834546
+Nt5c2,2.3519572558259344e-06,7.7888703,"[np.float32(0.0), np.float32(2.2014832)]",1.673198488840427e-05
+Phrf1,4.414097162696146e-10,7.7471275,"[np.float32(0.0), np.float32(2.1384132)]",4.1043809418180814e-07
+Zfp148,2.0661550491779334e-06,7.7241077,"[np.float32(0.0), np.float32(2.1044047)]",1.5419391871556447e-05
+Smarca2,0.00030452552234947627,7.7162514,"[np.float32(0.0), np.float32(2.092922)]",0.000792444022692448
+Xrcc1,0.00026528672571631326,7.7133193,"[np.float32(2.0886524), np.float32(0.0)]",0.0007080620025894752
+Unc5c,0.00023547403301001774,7.7090583,"[np.float32(2.0824628), np.float32(0.0)]",0.0006403661566304407
+Mark2,1.163499240178542e-06,7.7013702,"[np.float32(0.0), np.float32(2.0713422)]",1.077676771472303e-05
+Vps13d,0.03265009742950511,7.699883,"[np.float32(0.0), np.float32(2.0691977)]",0.04541883441680599
+Cyld,0.014865844721932895,7.69557,"[np.float32(2.062991), np.float32(0.0)]",0.022485040804152343
+Tnpo3,0.00030026541277058954,7.687413,"[np.float32(2.0513039), np.float32(0.0)]",0.0007824465004091546
+Riok3,8.589682510746202e-05,7.681782,"[np.float32(2.043273), np.float32(0.0)]",0.00027147459421632
+Sumf2,7.283942037865888e-05,7.6776304,"[np.float32(2.0373733), np.float32(0.0)]",0.00023660165890359512
+Mga,0.00029701631221334073,7.6622458,"[np.float32(2.0156567), np.float32(0.0)]",0.0007761417879206152
+Cdh13,0.0012613448395125616,7.627936,"[np.float32(1.9680513), np.float32(0.0)]",0.0025792089559868885
+Lima1,0.0037631232564110154,7.6159234,"[np.float32(1.9516492), np.float32(0.0)]",0.006574046323758178
+Lta4h,0.0005648692216716706,7.615356,"[np.float32(1.9508781), np.float32(0.0)]",0.0013047781651206118
+Usp31,7.987536710930129e-06,7.5911403,"[np.float32(1.9182392), np.float32(0.0)]",4.381569192791318e-05
+Sdhaf2,2.923036655651703e-07,7.5893493,"[np.float32(1.9158471), np.float32(0.0)]",4.674360327114817e-06
+Ano3,0.00013110806119151359,7.5707254,"[np.float32(0.0), np.float32(1.8911457)]",0.0003773895115220337
+Ufd1l,5.002740013131806e-06,7.5680633,"[np.float32(0.0), np.float32(1.8876407)]",2.9809320269329962e-05
+Mdm4,5.405388372057373e-06,7.5594287,"[np.float32(1.8763176), np.float32(0.0)]",3.1903727583972694e-05
+Ythdf2,0.0011820687898191765,7.5469985,"[np.float32(1.8601351), np.float32(0.0)]",0.0024438129345322425
+Sephs1,0.00039143736401608666,7.543505,"[np.float32(1.855612), np.float32(0.0)]",0.0009561087572768905
+Nfrkb,0.007252155571977833,7.524178,"[np.float32(1.8307861), np.float32(0.0)]",0.01185046556783452
+Fibp,0.003284785106184777,7.517446,"[np.float32(1.8222162), np.float32(0.0)]",0.0058089158163248744
+Zfp574,1.9102395488201454e-05,7.513113,"[np.float32(1.8167218), np.float32(0.0)]",8.389807971461249e-05
+Fbxl20,5.295760590375442e-05,7.5103006,"[np.float32(1.8131639), np.float32(0.0)]",0.00018048029261552736
+Ythdc2,0.0024412384938629827,7.5007634,"[np.float32(1.8011516), np.float32(0.0)]",0.004614941111265526
+Ext1,0.001927924322497566,7.498436,"[np.float32(1.7982318), np.float32(0.0)]",0.0037692229962308734
+Atp11b,0.020519453124877636,7.4644704,"[np.float32(1.7561579), np.float32(0.0)]",0.03015859921181937
+Ick,3.6783099488482357e-05,7.4643507,"[np.float32(1.7560111), np.float32(0.0)]",0.00013441636551357519
+Huwe1,1.957203529005327e-08,7.442181,"[np.float32(0.0), np.float32(1.7290809)]",1.0770375890496962e-06
+Rbfox1,6.929107032095377e-05,7.4377537,"[np.float32(0.0), np.float32(1.7237519)]",0.00022986452583422787
+Capn2,4.5337631646664366e-07,7.4308853,"[np.float32(1.7155175), np.float32(0.0)]",6.283459911919188e-06
+Sp4,3.5920971091584953e-09,7.4300485,"[np.float32(0.0), np.float32(1.714517)]",6.941221738016714e-07
+Ampd3,0.005940498103324304,7.4295387,"[np.float32(1.7139078), np.float32(0.0)]",0.009914961597965899
+Syt13,0.002149077341011431,7.4295387,"[np.float32(1.7139078), np.float32(0.0)]",0.004132501238471108
+Las1l,1.4066289850840104e-06,7.3955812,"[np.float32(1.6738049), np.float32(0.0)]",1.224094340042876e-05
+Akap8l,6.906936651282757e-07,7.3743467,"[np.float32(0.0), np.float32(1.649203)]",8.200345653951462e-06
+Myt1l,2.9640981668197808e-05,7.35954,"[np.float32(0.0), np.float32(1.6322614)]",0.00012215479449603105
+Lysmd4,0.0003072409686447463,7.3114095,"[np.float32(1.578377), np.float32(0.0)]",0.0007972924442917064
+Pdzd8,2.2227466085557836e-06,7.3109255,"[np.float32(0.0), np.float32(1.5778444)]",1.6119220560495628e-05
+Ep400,3.749842546229652e-05,7.2989283,"[np.float32(1.5646945), np.float32(0.0)]",0.00013470892825368503
+Arglu1,5.744293728134207e-08,7.2973056,"[np.float32(1.5629243), np.float32(0.0)]",1.6793083695842348e-06
+Rnh1,4.1147091075816125e-06,7.294005,"[np.float32(1.5593301), np.float32(0.0)]",2.6008853852314857e-05
+Appl2,8.600954537547619e-07,7.278246,"[np.float32(0.0), np.float32(1.542281)]",9.143789720740064e-06
+Tada2a,0.0006331863765843681,7.259395,"[np.float32(1.5221304), np.float32(0.0)]",0.0014311377081582847
+Zfp182,1.1401911798015339e-05,7.2554502,"[np.float32(0.0), np.float32(1.5179465)]",5.584548946095994e-05
+Pgm2l1,9.833716292873159e-06,7.219368,"[np.float32(0.0), np.float32(1.4802059)]",4.963651573266607e-05
+Nup37,1.2674893836754e-06,7.1924696,"[np.float32(0.0), np.float32(1.4526789)]",1.1456389550032238e-05
+Pbdc1,0.00086969740354643,7.188246,"[np.float32(1.4484032), np.float32(0.0)]",0.0019121079224857468
+Mphosph10,3.046383386287998e-05,7.1403003,"[np.float32(1.400732), np.float32(0.0)]",0.00012526996298340318
+Msl2,3.882804260149863e-06,7.1397705,"[np.float32(1.4002143), np.float32(0.0)]",2.477658455621462e-05
+Clpx,7.283942037865888e-05,7.1067195,"[np.float32(1.3682745), np.float32(0.0)]",0.00023660165890359512
+Chordc1,0.00025548652912376995,7.10625,"[np.float32(1.3678259), np.float32(0.0)]",0.0006877917927921922
+Smarca5,1.0519005725640359e-08,7.088132,"[np.float32(0.0), np.float32(1.350631)]",7.896715598504087e-07
+Alg14,7.259418083921958e-05,7.073665,"[np.float32(1.3370553), np.float32(0.0)]",0.00023660165890359512
+Gabrb3,0.00243057610723141,7.0694613,"[np.float32(0.0), np.float32(1.3331356)]",0.004607505467710201
+Actn4,3.486868493564377e-06,7.0571,"[np.float32(1.3216766), np.float32(0.0)]",2.2731466729822125e-05
+Golga5,7.887290635281898e-07,7.053115,"[np.float32(1.3180032), np.float32(0.0)]",8.689541299910302e-06
+Ssh2,2.6557873737190294e-07,7.0480833,"[np.float32(1.31338), np.float32(0.0)]",4.397325819671065e-06
+Kdm5b,3.542451371557169e-05,7.029646,"[np.float32(0.0), np.float32(1.296575)]",0.00013072833365253378
+Tab1,2.4122811541642897e-07,6.999636,"[np.float32(1.2696773), np.float32(0.0)]",4.066106341839086e-06
+Scn2a1,0.00010354408305441785,6.986207,"[np.float32(0.0), np.float32(1.2578208)]",0.00031863647926778915
+Brd4,2.1050275889937754e-06,6.9835415,"[np.float32(0.0), np.float32(1.2554806)]",1.556721983797373e-05
+Ap1s2,0.0024256473785502376,6.961005,"[np.float32(1.2358661), np.float32(0.0)]",0.004602825806559325
+Rabl6,0.02547445277047503,6.9533634,"[np.float32(0.0), np.float32(1.2292844)]",0.03646725411901972
+Impact,0.005128669946394288,6.947603,"[np.float32(1.224346), np.float32(0.0)]",0.008606046161169249
+Slc39a6,1.57351728037522e-05,6.9300656,"[np.float32(0.0), np.float32(1.209432)]",7.207939229684946e-05
+Slc43a2,0.00040734938363856036,6.8977895,"[np.float32(0.0), np.float32(1.1824539)]",0.000989806099724346
+Cnot2,8.653575469808194e-07,6.8932304,"[np.float32(1.1786913), np.float32(0.0)]",9.143789720740064e-06
+Zmym5,0.00023359774618842452,6.868674,"[np.float32(1.1586297), np.float32(0.0)]",0.0006361883305946758
+Anks1b,0.00011349743220631483,6.856513,"[np.float32(0.0), np.float32(1.1488204)]",0.0003333652993061461
+Dcun1d2,8.936804465654896e-07,6.841763,"[np.float32(0.0), np.float32(1.1370327)]",9.237989588530557e-06
+Ppp2r5a,3.7371629151000156e-05,6.810206,"[np.float32(1.1122154), np.float32(0.0)]",0.00013470892825368503
+Pcf11,1.7226733829456576e-07,6.791435,"[np.float32(0.0), np.float32(1.0977086)]",3.1912098014765597e-06
+Brox,0.0017330632771201302,6.789763,"[np.float32(1.0964259), np.float32(0.0)]",0.0034349167282751738
+Csmd2,0.00010354408305441785,6.775195,"[np.float32(0.0), np.float32(1.0853099)]",0.00031863647926778915
+Nfe2l3,3.2934153548632956e-05,6.7622213,"[np.float32(1.0755042), np.float32(0.0)]",0.00012613985252110196
+Fam76a,3.1288400836126045e-08,6.762011,"[np.float32(0.0), np.float32(1.075346)]",1.2195957909248297e-06
+Nav2,0.007948986912002394,6.73577,"[np.float32(1.0557832), np.float32(0.0)]",0.012910203569753888
+Mapk10,0.003903016724822512,6.7150483,"[np.float32(0.0), np.float32(1.0405844)]",0.006780449667727874
+Bzw2,5.17630347284473e-06,6.696577,"[np.float32(1.0272193), np.float32(0.0)]",3.0648303157254713e-05
+Glod4,2.1724171351507362e-08,6.6910906,"[np.float32(0.0), np.float32(1.0232823)]",1.0882928836451976e-06
+Zc3h13,8.10926506835015e-05,6.682592,"[np.float32(0.0), np.float32(1.0172131)]",0.00025891527206285203
+Vps36,3.758314299755403e-05,6.6454563,"[np.float32(0.9911097), np.float32(0.0)]",0.00013470892825368503
+Saysd1,0.0018577969841050504,6.613994,"[np.float32(0.96951383), np.float32(0.0)]",0.003655034865678811
+Wdr7,3.758314299755403e-05,6.606927,"[np.float32(0.9647275), np.float32(0.0)]",0.00013470892825368503
+Ralgapb,3.7199863621842196e-09,6.597729,"[np.float32(0.0), np.float32(0.95853305)]",6.941221738016714e-07
+Zmiz2,0.030294941658289838,6.597148,"[np.float32(0.9581429), np.float32(0.0)]",0.042363106010956865
+Cdk12,3.7918913002387213e-06,6.5824633,"[np.float32(0.0), np.float32(0.9483384)]",2.4380167088476454e-05
+Wdr37,8.259421161517782e-08,6.5729494,"[np.float32(0.0), np.float32(0.94203925)]",1.981202178615355e-06
+Adap1,4.217927159887822e-05,6.5691466,"[np.float32(0.9395334), np.float32(0.0)]",0.00014834100970206984
+9930021J03Rik,2.993993460005927e-07,6.5027,"[np.float32(0.8967919), np.float32(0.0)]",4.674480232836159e-06
+Erbb4,1.3901277733483943e-05,6.43693,"[np.float32(0.0), np.float32(0.8563812)]",6.576119877273319e-05
+Tmem62,5.816586890953594e-09,6.436578,"[np.float32(0.0), np.float32(0.8561697)]",6.941221738016714e-07
+Ahcyl1,6.634014552683414e-09,6.410846,"[np.float32(0.0), np.float32(0.8408579)]",7.189633497653282e-07
+Abi1,0.00025548652912376995,6.405046,"[np.float32(0.837444), np.float32(0.0)]",0.0006877917927921922
+Kdm3b,0.020519453124877636,6.381639,"[np.float32(0.0), np.float32(0.82380545)]",0.03015859921181937
+Ppp6c,0.005064723896054625,6.3815184,"[np.float32(0.82373565), np.float32(0.0)]",0.008521671231581119
+Clk4,2.170494087116723e-08,6.3805976,"[np.float32(0.0), np.float32(0.823204)]",1.0882928836451976e-06
+Rnf115,0.0029328770410249638,6.3737993,"[np.float32(0.81928676), np.float32(0.0)]",0.005379816611527165
+Gpm6a,9.413678516333764e-08,6.368337,"[np.float32(0.81615293), np.float32(0.0)]",2.12204728964584e-06
+Ndufaf7,0.0013462107021109245,6.354547,"[np.float32(0.0), np.float32(0.80829394)]",0.0027318440603574185
+Wipf3,4.783903497172795e-06,6.3328857,"[np.float32(0.0), np.float32(0.7960994)]",2.8780332614824117e-05
+0610040B10Rik,3.6729723083828144e-08,6.323614,"[np.float32(0.0), np.float32(0.7909355)]",1.3170092810742678e-06
+Brms1l,4.44685136935567e-06,6.316059,"[np.float32(0.7867521), np.float32(0.0)]",2.7013178285923568e-05
+Bclaf1,0.0005498193834933273,6.3006268,"[np.float32(0.0), np.float32(0.7782747)]",0.0012747361419033648
+Peli1,1.1046172172443693e-06,6.286414,"[np.float32(0.0), np.float32(0.7705473)]",1.0385622178212135e-05
+Cep97,4.44685136935567e-06,6.266494,"[np.float32(0.75984377), np.float32(0.0)]",2.7013178285923568e-05
+Rgs7bp,0.0016024807795065339,6.2663217,"[np.float32(0.0), np.float32(0.7597518)]",0.0031930154829145096
+Usp21,0.014630523161260347,6.2458677,"[np.float32(0.0), np.float32(0.7489158)]",0.022200899298230423
+Iqsec1,1.2766733671533187e-05,6.2241015,"[np.float32(0.0), np.float32(0.7375518)]",6.14050352170658e-05
+Psmd1,0.019068621065442302,6.2092204,"[np.float32(0.72988063), np.float32(0.0)]",0.028270515066119294
+Prrc2c,4.475655720286729e-06,6.1885824,"[np.float32(0.0), np.float32(0.71937186)]",2.710016780794974e-05
+Wrap53,2.7705523027165176e-06,6.1868625,"[np.float32(0.71850276), np.float32(0.0)]",1.8849830394118565e-05
+Naa15,2.273345426112617e-05,6.185919,"[np.float32(0.7180264), np.float32(0.0)]",9.755571771230977e-05
+Susd4,0.0002584163051139118,6.1575828,"[np.float32(0.0), np.float32(0.7038667)]",0.000693682793211089
+Rbm27,0.0002625607366807067,6.1566358,"[np.float32(0.7033983), np.float32(0.0)]",0.0007017873404708602
+Atp2c1,2.076796767307442e-06,6.1114464,"[np.float32(0.0), np.float32(0.6813988)]",1.5419391871556447e-05
+Elavl1,0.0010209848763598284,6.105493,"[np.float32(0.0), np.float32(0.6785518)]",0.002196084068900349
+Mt2,0.0002477998335244303,6.0934086,"[np.float32(0.6728083), np.float32(0.0)]",0.000671932592064071
+Hook3,4.238614432955234e-05,6.0877266,"[np.float32(0.6701243), np.float32(0.0)]",0.00014878888562962932
+Aagab,0.011675774669001864,6.0566688,"[np.float32(0.65563935), np.float32(0.0)]",0.018204478671418743
+Btrc,0.004083421842090308,6.05374,"[np.float32(0.65428936), np.float32(0.0)]",0.00699641233200638
+Rgl1,6.398503751990695e-05,6.0505586,"[np.float32(0.0), np.float32(0.6528261)]",0.00021492999138194953
+Clasp2,0.0169165067588828,6.0459323,"[np.float32(0.6507041), np.float32(0.0)]",0.025442752528834184
+Map6d1,1.1529975879676791e-08,6.039305,"[np.float32(0.64767605), np.float32(0.0)]",7.989846248472324e-07
+Mrpl21,8.92715140692774e-06,6.022392,"[np.float32(0.0), np.float32(0.6400109)]",4.785874006407393e-05
+Golga3,0.00853016170873073,6.016399,"[np.float32(0.6373162), np.float32(0.0)]",0.013723071846117967
+Sptbn1,0.0001791284616193956,5.990686,"[np.float32(0.62588155), np.float32(0.0)]",0.0005039839875035927
+Snx27,3.758314299755403e-05,5.9803853,"[np.float32(0.6213575), np.float32(0.0)]",0.00013470892825368503
+Tusc3,2.3495124678525334e-08,5.950375,"[np.float32(0.0), np.float32(0.60836005)]",1.1271635454748947e-06
+Gnptab,0.0013582326533142803,5.9328613,"[np.float32(0.60089874), np.float32(0.0)]",0.0027502741280855175
+Cisd2,0.00012731329792468765,5.9009385,"[np.float32(0.0), np.float32(0.5875297)]",0.0003675975006436583
+Scrib,0.00094906041323204,5.889461,"[np.float32(0.5827948), np.float32(0.0)]",0.0020647581780897056
+Mypop,0.0003275063748347085,5.8418536,"[np.float32(0.56355244), np.float32(0.0)]",0.0008451923135389511
+Ppp1r8,3.24213303022779e-05,5.8366756,"[np.float32(0.5614976), np.float32(0.0)]",0.00012613985252110196
+Rap1gap,0.0006068131256443149,5.8283324,"[np.float32(0.0), np.float32(0.55820215)]",0.0013896540490581557
+Tsnax,7.342399176115003e-05,5.807442,"[np.float32(0.0), np.float32(0.5500339)]",0.00023767523976662926
+Dync1li2,2.723403830845806e-07,5.7957664,"[np.float32(0.0), np.float32(0.5455198)]",4.4697268136074585e-06
+Rtn2,0.0002543599091812128,5.7930903,"[np.float32(0.54449034), np.float32(0.0)]",0.0006877274423093196
+Ap2b1,0.0005495179454219553,5.7854056,"[np.float32(0.0), np.float32(0.5415446)]",0.0012747361419033648
+Scaf11,0.00036274075577403414,5.7832,"[np.float32(0.5407019), np.float32(0.0)]",0.0008953666940016066
+Nars,1.8551260044496503e-06,5.7712693,"[np.float32(0.0), np.float32(0.53616667)]",1.4283706807923029e-05
+Zdhhc21,2.888070166682286e-05,5.768861,"[np.float32(0.5352557), np.float32(0.0)]",0.00011981328784617643
+Slco3a1,5.057222970865209e-05,5.709691,"[np.float32(0.5133452), np.float32(0.0)]",0.00017393500328104425
+Smap2,0.02468876531400387,5.6756816,"[np.float32(0.0), np.float32(0.5011524)]",0.03542383428105923
+Higd1a,2.1746654443276622e-08,5.6711125,"[np.float32(0.0), np.float32(0.499536)]",1.0882928836451976e-06
+Snx30,0.00017301705093600102,5.6643314,"[np.float32(0.49714684), np.float32(0.0)]",0.00048825777119345087
+Oard1,6.094278233755148e-08,5.6364098,"[np.float32(0.48742583), np.float32(0.0)]",1.7276355417205883e-06
+Arpc1b,2.7769494003427238e-08,5.6346292,"[np.float32(0.0), np.float32(0.48681238)]",1.1774116340731756e-06
+Stox2,7.517935536631382e-07,5.623579,"[np.float32(0.0), np.float32(0.48302165)]",8.47352854761284e-06
+Timm9,2.0289156848332636e-05,5.622224,"[np.float32(0.0), np.float32(0.48255873)]",8.828142433309387e-05
+Brd9,9.87338375454933e-06,5.618363,"[np.float32(0.0), np.float32(0.48124233)]",4.963651573266607e-05
+Myo5a,0.023097461852677702,5.589021,"[np.float32(0.0), np.float32(0.4713523)]",0.033319468871518876
+Lrrn1,3.9659983152698206e-08,5.5784965,"[np.float32(0.0), np.float32(0.46785355)]",1.3411526286821638e-06
+Amph,0.0004653414462956652,5.5782995,"[np.float32(0.46778825), np.float32(0.0)]",0.0011034902991371226
+Rftn2,0.0004809900240344052,5.5781016,"[np.float32(0.46772283), np.float32(0.0)]",0.0011358316817967722
+Lmtk3,1.725660523598435e-06,5.562197,"[np.float32(0.0), np.float32(0.46248522)]",1.3797909571165265e-05
+Agrn,0.00011349743220631483,5.542729,"[np.float32(0.0), np.float32(0.4561521)]",0.0003333652993061461
+Pex7,3.325236593269087e-05,5.532492,"[np.float32(0.0), np.float32(0.45285615)]",0.00012613985252110196
+Arhgef7,9.87338375454933e-06,5.5265903,"[np.float32(0.0), np.float32(0.45096663)]",4.963651573266607e-05
+Myo6,2.5657023137262192e-05,5.517643,"[np.float32(0.4481166), np.float32(0.0)]",0.00010864098274417208
+Trim59,0.0038272882571491473,5.509693,"[np.float32(0.44559917), np.float32(0.0)]",0.006661261701512608
+Impdh2,7.812140830840804e-08,5.507422,"[np.float32(0.44488248), np.float32(0.0)]",1.9794405059649843e-06
+Basp1,0.0026476154982048496,5.493707,"[np.float32(0.0), np.float32(0.44057876)]",0.004929043380240073
+Ina,6.342448436317263e-05,5.487417,"[np.float32(0.0), np.float32(0.43861842)]",0.0002137645028907055
+Acot7,1.123245042166433e-06,5.468077,"[np.float32(0.0), np.float32(0.43264464)]",1.0507957369466982e-05
+Zcchc24,8.778339731781428e-08,5.437485,"[np.float32(0.4233573), np.float32(0.0)]",2.053034204770381e-06
+Snx2,9.097892316648933e-06,5.4084716,"[np.float32(0.41472933), np.float32(0.0)]",4.818714192896233e-05
+Srp68,0.012751823216497453,5.401564,"[np.float32(0.4127005), np.float32(0.0)]",0.01971790184964193
+Dars,0.00020017041311743108,5.3968353,"[np.float32(0.41131738), np.float32(0.0)]",0.0005507630043275199
+Kansl2,0.006894556492162938,5.3735695,"[np.float32(0.40457737), np.float32(0.0)]",0.01131553964634812
+Ahi1,2.1357599297387137e-06,5.373507,"[np.float32(0.0), np.float32(0.40455937)]",1.5732310348587142e-05
+Acd,3.143444760497067e-09,5.317553,"[np.float32(0.0), np.float32(0.3887888)]",6.941221738016714e-07
+Fam114a2,7.92331188847534e-07,5.296657,"[np.float32(0.38305438), np.float32(0.0)]",8.689541299910302e-06
+Ddx17,1.8469343886062798e-08,5.294852,"[np.float32(0.38256288), np.float32(0.0)]",1.0770375890496962e-06
+2300009A05Rik,0.01962429670936431,5.2910953,"[np.float32(0.3815421), np.float32(0.0)]",0.028911070191512303
+Rbm39,1.2477595518042898e-05,5.2669983,"[np.float32(0.0), np.float32(0.37505645)]",6.0480780347819325e-05
+Erc1,2.661938662483172e-06,5.241808,"[np.float32(0.0), np.float32(0.3683915)]",1.8310614843772113e-05
+Hid1,1.437295038012549e-05,5.2061615,"[np.float32(0.35915667), np.float32(0.0)]",6.685295824757087e-05
+Pura,9.895467861188908e-06,5.2007284,"[np.float32(0.0), np.float32(0.35776916)]",4.963651573266607e-05
+Exosc7,0.006083541718539981,5.16887,"[np.float32(0.34973687), np.float32(0.0)]",0.010126607255683545
+Ylpm1,0.00025548652912376995,5.1393256,"[np.float32(0.34244484), np.float32(0.0)]",0.0006877917927921922
+Cdc26,1.3784385543349334e-06,5.1214223,"[np.float32(0.3380981), np.float32(0.0)]",1.2108256033618125e-05
+Mkl2,2.3519572558259344e-06,5.1108084,"[np.float32(0.0), np.float32(0.3355466)]",1.673198488840427e-05
+Wbp4,2.7747272606271437e-07,5.1040525,"[np.float32(0.33393225), np.float32(0.0)]",4.505886473902976e-06
+Dnajc15,2.8617538676916934e-06,5.094348,"[np.float32(0.0), np.float32(0.3316265)]",1.9191188123480857e-05
+Pigz,4.44685136935567e-06,5.0710025,"[np.float32(0.32614282), np.float32(0.0)]",2.7013178285923568e-05
+Wasf1,0.022272721356494198,5.0514083,"[np.float32(0.0), np.float32(0.3216083)]",0.03225407249071257
+Secisbp2l,1.6181542718981036e-06,5.029032,"[np.float32(0.0), np.float32(0.3165048)]",1.3278801064567333e-05
+Asb1,3.5020150537034654e-05,5.003838,"[np.float32(0.3108524), np.float32(0.0)]",0.00013026382038726012
+Mdm2,7.283942037865888e-05,4.9194355,"[np.float32(0.29261997), np.float32(0.0)]",0.00023660165890359512
+Srsf11,0.0010103239463027575,4.897998,"[np.float32(0.0), np.float32(0.28815645)]",0.00219294211546689
+Pnrc1,6.566386275728709e-05,4.873871,"[np.float32(0.28321168), np.float32(0.0)]",0.00022017399143169205
+Pkp4,0.027746260853380413,4.8658595,"[np.float32(0.28158805), np.float32(0.0)]",0.03938790140870618
+Tfdp2,0.0006083094029338096,4.852462,"[np.float32(0.27889273), np.float32(0.0)]",0.001391377619668897
+Ptrhd1,8.069604674009563e-09,4.8263106,"[np.float32(0.0), np.float32(0.27370325)]",7.189633497653282e-07
+Prmt2,9.29574587903479e-06,4.825324,"[np.float32(0.27350923), np.float32(0.0)]",4.85819568147321e-05
+Dst,4.014139348273713e-08,4.8188667,"[np.float32(0.0), np.float32(0.27224317)]",1.3411526286821638e-06
+Zfp511,4.3979205886799465e-05,4.810892,"[np.float32(0.2706874), np.float32(0.0)]",0.000154091936730715
+Knop1,1.826064793813707e-05,4.8003106,"[np.float32(0.2686362), np.float32(0.0)]",8.173605811544128e-05
+Syp,6.225015371621785e-07,4.7802515,"[np.float32(0.0), np.float32(0.26478884)]",7.76466917353624e-06
+C1galt1c1,9.717930245399135e-07,4.7424507,"[np.float32(0.0), np.float32(0.2576824)]",9.469920567261343e-06
+Yipf4,7.512537615146391e-07,4.741111,"[np.float32(0.0), np.float32(0.257434)]",8.47352854761284e-06
+Kpna3,9.717930245399135e-07,4.739465,"[np.float32(0.0), np.float32(0.25712907)]",9.469920567261343e-06
+Zfp462,0.030151261301315242,4.7303934,"[np.float32(0.25545463), np.float32(0.0)]",0.04219372467820555
+Zfp704,6.576030031485427e-06,4.684425,"[np.float32(0.0), np.float32(0.24712978)]",3.7626153482902855e-05
+Tpst1,1.1271483325651316e-05,4.6786957,"[np.float32(0.0), np.float32(0.24611068)]",5.549722447972003e-05
+Ppig,4.341583388575504e-08,4.6744027,"[np.float32(0.0), np.float32(0.24534975)]",1.4251057052675031e-06
+Chd7,1.4790207826709285e-07,4.6718717,"[np.float32(0.0), np.float32(0.2449022)]",2.852832870492069e-06
+Spg21,4.039325098775536e-07,4.647458,"[np.float32(0.0), np.float32(0.24062496)]",5.725437318037143e-06
+Arhgef9,0.0010404548729486501,4.6193886,"[np.float32(0.0), np.float32(0.23579583)]",0.002196084068900349
+Vti1b,0.00036187545079479266,4.6189265,"[np.float32(0.2357171), np.float32(0.0)]",0.000894410790537724
+Letmd1,9.87338375454933e-06,4.6021686,"[np.float32(0.0), np.float32(0.23287943)]",4.963651573266607e-05
+Mmd2,0.006894165969417836,4.57395,"[np.float32(0.22817495), np.float32(0.0)]",0.01131553964634812
+Mprip,0.0012547078900310203,4.5600796,"[np.float32(0.22589609), np.float32(0.0)]",0.0025684447070547472
+Nbr1,4.0309547337687544e-07,4.5398297,"[np.float32(0.22260815), np.float32(0.0)]",5.725437318037143e-06
+Deaf1,3.730705071990176e-08,4.5389843,"[np.float32(0.0), np.float32(0.22247186)]",1.3170092810742678e-06
+Ostf1,1.6467375942383267e-06,4.493724,"[np.float32(0.21529193), np.float32(0.0)]",1.3454349514497421e-05
+Cbx4,0.025680122461829227,4.381411,"[np.float32(0.19841842), np.float32(0.0)]",0.03670550735376813
+Ttc1,3.543410475077548e-08,4.361441,"[np.float32(0.0), np.float32(0.19555335)]",1.2999452938960964e-06
+Epn2,3.1947153718529783e-06,4.340566,"[np.float32(0.19260055), np.float32(0.0)]",2.104687486174973e-05
+Pdhb,0.0021366170879375253,4.3320484,"[np.float32(0.1914079), np.float32(0.0)]",0.0041127680777069036
+Psma1,4.7340354952409856e-05,4.322715,"[np.float32(0.0), np.float32(0.19010909)]",0.00016402556317770157
+Psmd14,0.027874196099930748,4.17984,"[np.float32(0.17124133), np.float32(0.0)]",0.039531437944558705
+S100a6,9.699234488814496e-06,4.0911846,"[np.float32(0.0), np.float32(0.16043913)]",4.963651573266607e-05
+Nup88,9.717930245399135e-07,4.067304,"[np.float32(0.0), np.float32(0.1576411)]",9.469920567261343e-06
+Wipi1,3.252264652679966e-08,4.0538845,"[np.float32(0.0), np.float32(0.15608896)]",1.241834115339636e-06
+Itgb1bp1,0.00021795364466671937,4.015131,"[np.float32(0.15168689), np.float32(0.0)]",0.0005979344122748269
+Rprd1a,0.0040227368760927,3.9337084,"[np.float32(0.0), np.float32(0.14281437)]",0.006911423962506375
+Camk2a,1.0640003323341644e-05,3.9045846,"[np.float32(0.0), np.float32(0.13976042)]",5.280489712989977e-05
+Jagn1,2.076796767307442e-06,3.895364,"[np.float32(0.0), np.float32(0.13880631)]",1.5419391871556447e-05
+Csnk1e,3.758314299755403e-05,3.879795,"[np.float32(0.13720909), np.float32(0.0)]",0.00013470892825368503
+Sparcl1,1.3953605511905439e-05,3.827042,"[np.float32(0.0), np.float32(0.13192354)]",6.576119877273319e-05
+Cdc42se2,1.124310116537048e-08,3.7290745,"[np.float32(0.12260602), np.float32(0.0)]",7.989846248472324e-07
+Arid4b,0.01590477103134744,3.7276883,"[np.float32(0.12247868), np.float32(0.0)]",0.023940327111545503
+Gria2,1.766438068545316e-05,3.7265782,"[np.float32(0.0), np.float32(0.12237678)]",7.983105377411319e-05
+Sybu,2.210322265019642e-08,3.710381,"[np.float32(0.66555697), np.float32(8.832966)]",1.0882928836451976e-06
+Sccpdh,0.00020815778337847192,3.6967094,"[np.float32(0.1196643), np.float32(0.0)]",0.0005718989907505447
+Tnik,1.7751039147099557e-08,3.6630585,"[np.float32(26.227709), np.float32(2.0612638)]",1.0770375890496962e-06
+Pcmt1,2.759068088303854e-06,3.6605024,"[np.float32(0.0), np.float32(0.11645064)]",1.88402058146588e-05
+Nfib,1.7232458764279668e-06,3.6194932,"[np.float32(1.1115391), np.float32(0.08125116)]",1.3797909571165265e-05
+Hdgfrp3,0.0040227368760927,3.608229,"[np.float32(0.0), np.float32(0.111950934)]",0.006911423962506375
+Cnrip1,3.1891853713184235e-05,3.6080196,"[np.float32(0.111933246), np.float32(0.0)]",0.00012613985252110196
+Zbtb20,2.8707508667573933e-08,3.576634,"[np.float32(0.0), np.float32(0.10930923)]",1.1774116340731756e-06
+Anapc5,0.0003909631561576984,3.518085,"[np.float32(0.10456425), np.float32(0.0)]",0.0009561087572768905
+Tspan7,0.0004485075961708001,3.4782012,"[np.float32(0.10144046), np.float32(0.0)]",0.0010730917038817992
+Znrd1,1.6015434251005846e-06,3.4284568,"[np.float32(0.0), np.float32(0.09766346)]",1.3278801064567333e-05
+Apoa1bp,1.0066872952049155e-08,3.419476,"[np.float32(0.0), np.float32(0.096995346)]",7.896715598504087e-07
+Denr,0.002897484857586394,3.3940752,"[np.float32(0.09512801), np.float32(0.0)]",0.00535764577368299
+Cnpy2,0.008400630240683915,3.2956257,"[np.float32(0.08819338), np.float32(0.0)]",0.013549637224413453
+Ergic1,1.948357372508817e-07,3.1649172,"[np.float32(5.956999), np.float32(0.65530527)]",3.5392006252077636e-06
+Srek1,2.142406988349083e-05,3.150533,"[np.float32(4.4584093), np.float32(0.49320865)]",9.278804340743366e-05
+Psph,0.0020348785635862223,3.1271102,"[np.float32(0.07736833), np.float32(0.0)]",0.003933117554204362
+Mycbp2,4.82506228613669e-09,3.0719056,"[np.float32(0.19764204), np.float32(0.0146933235)]",6.941221738016714e-07
+Aff4,2.8079505639352463e-06,3.065116,"[np.float32(2.5330524), np.float32(0.29385298)]",1.903067217762896e-05
+Cadm2,0.00011349743220631483,3.0367904,"[np.float32(0.0), np.float32(0.07206632)]",0.0003333652993061461
+Mrpl52,5.743610310436767e-09,3.0209072,"[np.float32(0.73458076), np.float32(0.08173353)]",6.941221738016714e-07
+Hmox2,1.625078875294584e-05,3.0187275,"[np.float32(0.07104525), np.float32(0.0)]",7.397865147630575e-05
+Eif2s2,3.86908440593882e-07,2.959528,"[np.float32(0.0), np.float32(0.06778695)]",5.641791701635842e-06
+Snrnp48,3.0037613328964318e-06,2.92956,"[np.float32(21.525696), np.float32(2.8166597)]",1.992921082925257e-05
+Pdcd6,3.282164466874646e-05,2.9128659,"[np.float32(0.065311275), np.float32(0.0)]",0.00012613985252110196
+Rpl36a,0.009261728245149668,2.814792,"[np.float32(0.060361777), np.float32(0.0)]",0.014760386325958287
+Lsm1,4.6964627643879825e-08,2.7875416,"[np.float32(0.0), np.float32(0.05904522)]",1.489335903757613e-06
+Klf7,7.283789296622125e-08,2.785922,"[np.float32(0.0), np.float32(0.05896776)]",1.919432362532394e-06
+Gphn,0.000293814789355947,2.7854474,"[np.float32(19.683165), np.float32(2.8463557)]",0.0007699264298108919
+Rnf14,1.882093709700454e-05,2.774215,"[np.float32(0.058410365), np.float32(0.0)]",8.315707294872946e-05
+Cxxc5,4.44685136935567e-06,2.7534056,"[np.float32(0.0574307), np.float32(0.0)]",2.7013178285923568e-05
+Nckap1,9.87338375454933e-06,2.7395523,"[np.float32(0.0), np.float32(0.0567863)]",4.963651573266607e-05
+Manbal,2.2978326374812199e-07,2.7288811,"[np.float32(0.056294125), np.float32(0.0)]",3.944261343786571e-06
+Ptn,1.1927143995580485e-06,2.7271574,"[np.float32(0.6101811), np.float32(4.096527)]",1.0885700690600529e-05
+Hace1,1.4844221158929027e-06,2.723768,"[np.float32(4.6260266), np.float32(0.69179475)]",1.2624335358343732e-05
+Zeb2,7.283942037865888e-05,2.7211688,"[np.float32(0.05594068), np.float32(0.0)]",0.00023660165890359512
+Nf1,3.9636067324719745e-05,2.7052417,"[np.float32(1.5597215), np.float32(10.227206)]",0.00014122940495343484
+Cmip,9.717930245399135e-07,2.6906388,"[np.float32(0.0), np.float32(0.054559916)]",9.469920567261343e-06
+Mrps16,4.4612435435634156e-05,2.6696954,"[np.float32(0.053629477), np.float32(0.0)]",0.00015572736324640207
+Cplx2,1.3863294870713292e-05,2.6640067,"[np.float32(0.0), np.float32(0.053379077)]",6.576119877273319e-05
+Lurap1l,0.004758048513812537,2.6462834,"[np.float32(0.30291343), np.float32(1.9490019)]",0.00804183267330014
+Dtna,1.3243354005868025e-06,2.6397579,"[np.float32(1.8130525), np.float32(11.351757)]",1.1687884596688241e-05
+Selt,0.00018834465668671695,2.622763,"[np.float32(0.0), np.float32(0.051592853)]",0.0005251756373485058
+Mt3,0.0011988268339353288,2.612718,"[np.float32(0.0), np.float32(0.051165495)]",0.002472993391723264
+Commd4,5.706155617580261e-06,2.5568287,"[np.float32(0.0), np.float32(0.048841283)]",3.3363178626539584e-05
+Eif1ax,0.0021772098548719647,2.5504239,"[np.float32(0.04858064), np.float32(0.0)]",0.004173729137771974
+Fam96b,2.894758694140357e-08,2.5140603,"[np.float32(0.04712255), np.float32(0.0)]",1.1774116340731756e-06
+Rmdn1,1.3567572852228665e-07,2.5073617,"[np.float32(66.954994), np.float32(11.767599)]",2.759231392013025e-06
+Zfand6,0.0011780309027198791,2.498932,"[np.float32(0.046526678), np.float32(0.0)]",0.002438159091801874
+Abr,0.00010135212935844583,2.4959307,"[np.float32(0.0), np.float32(0.046409212)]",0.0003149291771765997
+Fermt2,1.1401911798015339e-05,2.4943185,"[np.float32(0.0), np.float32(0.04634621)]",5.584548946095994e-05
+Inf2,4.493818630717653e-06,2.4905598,"[np.float32(2.1437423), np.float32(0.3732309)]",2.712236986475074e-05
+Camk2g,9.87338375454933e-06,2.467202,"[np.float32(0.0), np.float32(0.045297034)]",4.963651573266607e-05
+Bloc1s2,0.0040395156823727334,2.4423358,"[np.float32(0.0443521), np.float32(0.0)]",0.0069275287275154755
+Oxct1,0.0011857063217821653,2.4264834,"[np.float32(0.043758143), np.float32(0.0)]",0.0024486275144088646
+Nuak1,5.461124876741289e-07,2.418038,"[np.float32(6.4617085), np.float32(1.2009245)]",7.046734237505484e-06
+Pvrl1,2.6393196903269297e-06,2.408311,"[np.float32(0.48088104), np.float32(2.595854)]",1.8222018969009912e-05
+Slc6a6,3.485379232483248e-05,2.3972218,"[np.float32(0.042678773), np.float32(0.0)]",0.00012999481322003637
+Mgrn1,3.758314299755403e-05,2.373766,"[np.float32(0.04182923), np.float32(0.0)]",0.00013470892825368503
+Rtn4,0.0007420883834881079,2.3570983,"[np.float32(0.041233882), np.float32(0.0)]",0.0016489873699599166
+Ggps1,1.3927922673673652e-06,2.3511715,"[np.float32(32.34986), np.float32(6.332106)]",1.2177169776842711e-05
+Ddx50,0.008956597047352348,2.3352563,"[np.float32(50.554092), np.float32(10.009822)]",0.014298458255628194
+Neo1,1.776161672931343e-06,2.329057,"[np.float32(3.3707712), np.float32(0.6628213)]",1.4126046231655621e-05
+Vcp,4.44685136935567e-06,2.3279035,"[np.float32(0.04020752), np.float32(0.0)]",2.7013178285923568e-05
+Zmat2,0.0002716094425012979,2.3147528,"[np.float32(0.039751947), np.float32(0.0)]",0.0007218483905112618
+Xkr4,0.009856127332602802,2.311608,"[np.float32(31.537716), np.float32(6.3448386)]",0.015601365684686837
+Xpo7,0.0013404508209112576,2.3093917,"[np.float32(48.44859), np.float32(9.7663)]",0.0027231091052388307
+Matr3,1.378249211808835e-07,2.3047905,"[np.float32(0.64609116), np.float32(0.12278625)]",2.7728002960154086e-06
+Cmtm5,0.003203323283923882,2.2984016,"[np.float32(0.039191242), np.float32(0.0)]",0.0056702155763685745
+Ndufa6,2.8585623432073334e-08,2.2935462,"[np.float32(0.0), np.float32(0.039025966)]",1.1774116340731756e-06
+Fam120a,3.456468731184447e-07,2.2903926,"[np.float32(4.736855), np.float32(0.9603515)]",5.215365319392017e-06
+Bax,1.669116194303226e-06,2.2327986,"[np.float32(0.037004493), np.float32(0.0)]",1.3519118612733056e-05
+Mia3,1.2847295285283573e-07,2.2229233,"[np.float32(1.0418748), np.float32(4.900555)]",2.64146038228193e-06
+Cfdp1,4.71992353764073e-09,2.2104485,"[np.float32(0.12936515), np.float32(0.63500863)]",6.941221738016714e-07
+Map7d1,9.160172342642612e-07,2.198618,"[np.float32(0.026998091), np.float32(0.1598358)]",9.365400247587063e-06
+Heg1,2.0017276688566775e-06,2.186111,"[np.float32(16.647606), np.float32(3.650392)]",1.510174382431792e-05
+Uvrag,1.4558611531027528e-05,2.1820843,"[np.float32(4.1624875), np.float32(0.90943754)]",6.725719055445062e-05
+Daam2,8.009068219853719e-06,2.1725779,"[np.float32(5.835357), np.float32(26.34252)]",4.381569192791318e-05
+Mib2,0.0009761989007682537,2.1670508,"[np.float32(3.1513143), np.float32(14.187601)]",0.002121333499811153
+Rasal1,0.03419941761746546,2.1605353,"[np.float32(24.449661), np.float32(5.4609723)]",0.04746818276133373
+Plat,4.2859106851523715e-06,2.1455436,"[np.float32(11.35047), np.float32(50.255413)]",2.6729796306400293e-05
+Acbd6,0.02353051612120192,2.1231298,"[np.float32(0.033563796), np.float32(0.0)]",0.03389191352022232
+Endod1,3.2927116640379817e-09,2.1010857,"[np.float32(0.15969752), np.float32(0.71805686)]",6.941221738016714e-07
+Wbp11,2.1906501683534005e-06,2.099818,"[np.float32(0.38096437), np.float32(0.08120717)]",1.6010572128864112e-05
+Gria1,7.922524947022919e-07,2.0748775,"[np.float32(19.388931), np.float32(4.5944467)]",8.689541299910302e-06
+Heatr3,1.679532507934467e-07,2.0511496,"[np.float32(1.4077878), np.float32(0.33210048)]",3.1424053223453876e-06
+Stard13,2.0659386747235077e-05,2.050896,"[np.float32(30.736279), np.float32(7.410127)]",8.96837879444938e-05
+St7l,4.751350048133641e-05,2.046258,"[np.float32(1.0332695), np.float32(4.2990503)]",0.00016432118188647028
+Ccar1,1.7136316055272905e-06,2.0412686,"[np.float32(0.6660791), np.float32(2.772791)]",1.3797909571165265e-05
+Dnajc7,7.989958575884257e-08,2.0347877,"[np.float32(0.18327793), np.float32(0.037168298)]",1.981202178615355e-06
+Rtn3,8.139150166650752e-08,2.0272849,"[np.float32(0.0), np.float32(0.03076369)]",1.981202178615355e-06
+Man2a2,5.845652673340252e-09,2.02465,"[np.float32(0.6868367), np.float32(0.16125791)]",6.941221738016714e-07
+Syn2,1.6356401593364617e-07,1.984248,"[np.float32(5.4177427), np.float32(21.465212)]",3.0911946849682018e-06
+Scrn1,5.073848667764045e-07,1.9840015,"[np.float32(0.16905746), np.float32(0.69833124)]",6.780836326704664e-06
+Chd1,9.548390618520009e-07,1.9741714,"[np.float32(3.8532634), np.float32(15.168859)]",9.469920567261343e-06
+Aaas,6.394260568584454e-08,1.972187,"[np.float32(1.9832038), np.float32(7.8105836)]",1.7593619887972814e-06
+Pcmtd1,3.456468731184447e-07,1.965616,"[np.float32(12.9509325), np.float32(3.3083858)]",5.215365319392017e-06
+Ndufb3,3.3471215412948925e-07,1.9599571,"[np.float32(0.028905038), np.float32(0.0)]",5.175590416332847e-06
+Mrpl42,7.036731051928442e-07,1.9594676,"[np.float32(0.028891845), np.float32(0.0)]",8.226817921184841e-06
+Dennd5b,0.003982221161376102,1.9570339,"[np.float32(1.7092212), np.float32(6.665098)]",0.006879719107049572
+Atp9a,3.758314299755403e-05,1.9562248,"[np.float32(0.028804526), np.float32(0.0)]",0.00013470892825368503
+Cuedc2,0.012041276355613464,1.9107987,"[np.float32(0.02760172), np.float32(0.0)]",0.018743118187481523
+Cdk17,0.0026105977465302782,1.8940405,"[np.float32(0.883714), np.float32(0.23045598)]",0.004879548834923228
+Dip2b,1.9657971689719553e-06,1.8885027,"[np.float32(2.1700675), np.float32(0.57880837)]",1.4890714587637767e-05
+Rc3h2,7.965086010303337e-06,1.879437,"[np.float32(8.149876), np.float32(2.2077708)]",4.381569192791318e-05
+Psma2,2.2802789073627097e-05,1.8769116,"[np.float32(0.0), np.float32(0.026728796)]",9.762933262415628e-05
+Rabgap1l,1.0002017296718587e-05,1.8644122,"[np.float32(15.510708), np.float32(56.503933)]",4.99033982990946e-05
+Atp5e,8.519249132410552e-06,1.8592541,"[np.float32(0.0), np.float32(0.026282003)]",4.6067962794046655e-05
+Sarnp,2.503598202554538e-07,1.8507288,"[np.float32(0.0), np.float32(0.026068233)]",4.182350211588876e-06
+Zc3h6,0.0036597816303454555,1.8428695,"[np.float32(1.5734704), np.float32(5.6702695)]",0.00641147137675688
+Tmed10,5.115292951283402e-07,1.8353621,"[np.float32(0.040070772), np.float32(0.16868302)]",6.787739795639181e-06
+Psmc6,4.920964133865524e-06,1.8283255,"[np.float32(0.4353132), np.float32(0.1153963)]",2.941573129221212e-05
+Synrg,9.694019020312838e-05,1.8178293,"[np.float32(5.657033), np.float32(1.5974394)]",0.0003043206306544517
+Kri1,4.985906700648237e-07,1.809758,"[np.float32(4.9630556), np.float32(1.4085084)]",6.7112456380667995e-06
+Med25,2.8562361751720154e-06,1.7932459,"[np.float32(3.747102), np.float32(1.0740073)]",1.9191188123480857e-05
+Smek2,1.2377128888879323e-05,1.7803538,"[np.float32(4.7850485), np.float32(1.3858962)]",6.030627122680524e-05
+Chchd1,0.000310343399004237,1.775576,"[np.float32(0.024237465), np.float32(0.0)]",0.0008031154903691943
+Adk,2.1543698669942163e-05,1.7753392,"[np.float32(3.0715165), np.float32(0.89018995)]",9.309067023432283e-05
+Mrpl22,6.282852258347868e-08,1.7723914,"[np.float32(0.45076954), np.float32(1.5640798)]",1.7545099366222183e-06
+Ipo8,9.06187041834129e-07,1.770133,"[np.float32(3.969804), np.float32(13.56453)]",9.315801952042062e-06
+Fdps,3.21470681454175e-05,1.7682407,"[np.float32(0.18325357), np.float32(0.6482957)]",0.00012613985252110196
+Eml1,2.99806321721186e-07,1.7620329,"[np.float32(0.2163818), np.float32(0.7578321)]",4.674480232836159e-06
+Sgsm2,0.00019223825724988162,1.7610435,"[np.float32(14.382516), np.float32(4.236291)]",0.0005328559693548571
+1500011K16Rik,7.816339334572344e-06,1.7328908,"[np.float32(0.113777734), np.float32(0.40142876)]",4.326736951178951e-05
+Zfyve9,0.00027329066380308274,1.7315918,"[np.float32(16.638466), np.float32(5.003178)]",0.0007252862864901671
+Dnlz,7.283942037865888e-05,1.7303398,"[np.float32(0.023180595), np.float32(0.0)]",0.00023660165890359512
+Api5,4.020590544311305e-06,1.7174797,"[np.float32(5.282437), np.float32(1.5993215)]",2.5500084435276106e-05
+Rps12,0.014410719654738464,1.7161152,"[np.float32(0.022855053), np.float32(0.0)]",0.021935898098812415
+Ndufs4,1.180056386371999e-07,1.7002816,"[np.float32(0.32338002), np.float32(1.0733663)]",2.4532061098911224e-06
+Zcchc14,0.00043752332657429147,1.685609,"[np.float32(1.2630333), np.float32(0.38574997)]",0.0010508422901418478
+Ppp1r1a,0.0010319319228122247,1.6709522,"[np.float32(0.0), np.float32(0.021842467)]",0.002196084068900349
+Dcp1b,0.003408345411057589,1.6688992,"[np.float32(1.4570842), np.float32(0.45138803)]",0.005999072684937675
+Rfx3,2.267544645129959e-06,1.6504097,"[np.float32(15.055234), np.float32(47.283203)]",1.638060243644075e-05
+Ndufaf2,7.828893503014902e-08,1.6308707,"[np.float32(0.40397486), np.float32(0.1236697)]",1.9794405059649843e-06
+Prickle1,8.796804648493916e-07,1.6303797,"[np.float32(56.09192), np.float32(173.67844)]",9.143789720740064e-06
+Ttc3,0.02700661364826899,1.6300896,"[np.float32(0.043255944), np.float32(0.0072052977)]",0.038425379571035194
+Bcl10,0.00010479913509402407,1.6251458,"[np.float32(0.7533919), np.float32(2.3448606)]",0.00032196909977162403
+Eif3i,0.00019104199503290026,1.6082661,"[np.float32(0.02048852), np.float32(0.0)]",0.0005303257755290154
+Spcs2,0.00013402997269048,1.5837004,"[np.float32(0.019973766), np.float32(0.0)]",0.00038520749447601855
+Arfgef2,6.811549019086699e-05,1.5788559,"[np.float32(22.721004), np.float32(7.599141)]",0.0002271730519556366
+Man2b1,1.540055801289007e-06,1.57331,"[np.float32(29.410671), np.float32(9.87642)]",1.2979479298251045e-05
+Tmem69,8.370140417646617e-07,1.5713843,"[np.float32(2.2542667), np.float32(0.7518926)]",9.052331052842092e-06
+Sh3kbp1,3.379054031923001e-07,1.5581484,"[np.float32(1.8103381), np.float32(0.6081625)]",5.182139421088471e-06
+Ube2g1,6.2542359565473855e-06,1.5523744,"[np.float32(0.5206872), np.float32(1.5465027)]",3.5894710045092505e-05
+Ndufa3,7.283942037865888e-05,1.5512776,"[np.float32(0.019307656), np.float32(0.0)]",0.00023660165890359512
+Strn,2.027848186789484e-06,1.5408446,"[np.float32(0.899747), np.float32(2.6370432)]",1.5237365291096886e-05
+Ttyh2,3.8306010095521804e-07,1.5326009,"[np.float32(0.7426669), np.float32(2.1675174)]",5.641791701635842e-06
+Arhgef2,9.550399578211092e-07,1.530254,"[np.float32(0.19072708), np.float32(0.5697735)]",9.469920567261343e-06
+Erbb2ip,5.255556480238915e-07,1.5255575,"[np.float32(2.4539034), np.float32(7.083527)]",6.828573732310423e-06
+Camkk2,1.8622729874538343e-05,1.5092638,"[np.float32(3.704313), np.float32(1.2948027)]",8.295982760776485e-05
+Ephb1,1.0780367155067436e-06,1.4930664,"[np.float32(2.9887686), np.float32(8.431132)]",1.0186902498551097e-05
+Ank,9.717930245399135e-07,1.4908179,"[np.float32(0.0), np.float32(0.018104827)]",9.469920567261343e-06
+Sertad2,0.005791635769282419,1.4827452,"[np.float32(12.969887), np.float32(4.6342983)]",0.009683780629425742
+Top1,9.536830383558345e-06,1.480653,"[np.float32(0.0), np.float32(0.017907502)]",4.9427727555783e-05
+Dtd1,0.0012162472488881056,1.4693216,"[np.float32(0.24441592), np.float32(0.08188284)]",0.002503408803816992
+Zfp266,0.014474327743012662,1.4684659,"[np.float32(43.428257), np.float32(15.687123)]",0.021999567186983503
+Btbd9,3.893274109848796e-06,1.4677238,"[np.float32(16.834528), np.float32(46.579468)]",2.477658455621462e-05
+Dcc,1.3190821131883899e-06,1.4595846,"[np.float32(93.25376), np.float32(33.9005)]",1.1687884596688241e-05
+Tnrc6c,4.9547068071069166e-05,1.4462261,"[np.float32(8.4418745), np.float32(3.09167)]",0.00017072295462425489
+Cenpt,7.960187595539162e-05,1.4423864,"[np.float32(8.516954), np.float32(3.1275625)]",0.00025502587313790706
+Deb1,0.0005378536372228088,1.4351236,"[np.float32(0.01704053), np.float32(0.0)]",0.0012518645628512516
+Dnajc3,3.1484142771011135e-06,1.4307839,"[np.float32(1.4818834), np.float32(0.5433833)]",2.0815134672990048e-05
+Arfgap3,1.0560764152075151e-07,1.428388,"[np.float32(5.5047793), np.float32(14.832798)]",2.3246105562979535e-06
+Rplp2,8.17082550229299e-05,1.4279692,"[np.float32(0.047384206), np.float32(0.011327052)]",0.00026043636311397244
+Eprs,0.009569827367640435,1.4243989,"[np.float32(0.26774463), np.float32(0.73547393)]",0.015186723498604964
+Jph1,6.586078650844172e-05,1.411358,"[np.float32(8.159853), np.float32(21.720781)]",0.00022043923355508847
+Fam171b,8.94889365992015e-05,1.410776,"[np.float32(0.25087297), np.float32(0.08811676)]",0.00028187508480994277
+Psmd7,6.955655106577363e-05,1.4101784,"[np.float32(0.26148832), np.float32(0.09215159)]",0.00023022351374907913
+Rbm8a,6.907899068947498e-07,1.4094143,"[np.float32(0.112559006), np.float32(0.31555262)]",8.200345653951462e-06
+Abcg1,0.01293473456904153,1.4073955,"[np.float32(1.400374), np.float32(0.52169925)]",0.01993483391983254
+Akr1a1,2.2127383786815e-06,1.4047627,"[np.float32(0.0), np.float32(0.016477423)]",1.6109079791879715e-05
+Ypel2,8.459925280525435e-08,1.403246,"[np.float32(6.3330083), np.float32(2.388149)]",2.0036101518814033e-06
+Slpi,8.219295103144075e-05,1.3986651,"[np.float32(6.495594), np.float32(2.4574413)]",0.00026153573363915927
+Supt6,3.078119667704698e-08,1.3968005,"[np.float32(2.4371176), np.float32(6.433676)]",1.2195957909248297e-06
+Snap25,0.017063484286706853,1.3900942,"[np.float32(7.971292), np.float32(3.0351815)]",0.025622615650424174
+Gnaq,5.161025236942333e-06,1.3818804,"[np.float32(1.0292709), np.float32(0.3887873)]",3.0648303157254713e-05
+Luzp2,0.0005724297605728128,1.3816843,"[np.float32(28.161728), np.float32(73.39775)]",0.001318985322699178
+Rab6b,0.0122032655813312,1.3814753,"[np.float32(0.8169646), np.float32(0.3074106)]",0.01891657821265176
+N6amt2,0.03161581328824698,1.3748108,"[np.float32(4.6388235), np.float32(1.7826017)]",0.04407838052333093
+Rdh14,7.546014860127335e-05,1.3731961,"[np.float32(1.2009343), np.float32(0.45746315)]",0.00024342403109134904
+Fnta,1.1787413682160702e-06,1.3677455,"[np.float32(0.07454506), np.float32(0.20818287)]",1.0864163053853534e-05
+Upf2,2.6393196903269297e-06,1.3625827,"[np.float32(4.1757584), np.float32(1.6177808)]",1.8222018969009912e-05
+Copg2,3.535247441997228e-06,1.3542092,"[np.float32(4.704112), np.float32(12.041955)]",2.2887363197151607e-05
+Dlst,0.00809823253299823,1.345627,"[np.float32(2.05129), np.float32(0.8010825)]",0.013107087430138139
+Pafah1b2,0.0001513394382500398,1.3431187,"[np.float32(0.020954182), np.float32(0.06853049)]",0.0004303284026836238
+Arl3,6.754077601710084e-06,1.3330433,"[np.float32(0.48693573), np.float32(1.2419478)]",3.8527070709754775e-05
+Rps25,5.8846402970858185e-05,1.3326474,"[np.float32(0.023002988), np.float32(0.0031034732)]",0.00019909877026849125
+Cald1,5.704631239307426e-07,1.32651,"[np.float32(1.2997156), np.float32(3.2747045)]",7.260792550166119e-06
+Clmn,6.795590329368678e-08,1.3212895,"[np.float32(2.4166658), np.float32(6.05398)]",1.8426883342389562e-06
+Rala,0.006366308388741069,1.3174291,"[np.float32(0.3125293), np.float32(0.11941466)]",0.010578475129071528
+Pcm1,6.352381806907122e-05,1.3046288,"[np.float32(1.4609469), np.float32(0.58547646)]",0.0002137645028907055
+Nvl,6.637345025076955e-05,1.3024012,"[np.float32(2.5843608), np.float32(1.0418857)]",0.0002217584382485533
+Nsf,0.015587707272482858,1.3000084,"[np.float32(3.6735837), np.float32(1.4859911)]",0.023500886629182458
+Capn15,5.158169936537778e-05,1.297712,"[np.float32(12.205905), np.float32(4.959073)]",0.00017675706870443558
+Rac1,1.0861943402256733e-07,1.2895842,"[np.float32(0.0144457575), np.float32(0.0)]",2.3359420811060168e-06
+Pdxdc1,1.6945092471169358e-05,1.2835509,"[np.float32(1.171303), np.float32(2.8657334)]",7.676578211515223e-05
+Atp1b3,5.874199578270863e-06,1.277858,"[np.float32(0.14581017), np.float32(0.3678065)]",3.414476822411124e-05
+Ik,5.701662974420204e-06,1.2759002,"[np.float32(1.0572149), np.float32(0.43072492)]",3.3363178626539584e-05
+Hepacam,2.3817809328258316e-07,1.2705567,"[np.float32(10.258851), np.float32(4.2464366)]",4.051192841197392e-06
+Ube2d2a,9.027332056562224e-06,1.2666498,"[np.float32(0.05363397), np.float32(0.016447792)]",4.818714192896233e-05
+Tmem238,1.8426726524629036e-06,1.2599086,"[np.float32(5.0864573), np.float32(2.11813)]",1.4246448482471459e-05
+Eif3k,2.701486184153971e-05,1.2546182,"[np.float32(0.12372446), np.float32(0.046044517)]",0.00011332916256843228
+Gpr155,0.004379259661607008,1.2531896,"[np.float32(3.4834638), np.float32(1.4555768)]",0.007441953080646198
+Ano4,0.002801994077983725,1.237166,"[np.float32(2.0501902), np.float32(0.8639432)]",0.005190624673175792
+Son,0.002190683263184599,1.2337984,"[np.float32(0.021218086), np.float32(0.0032738203)]",0.004195259350479411
+Daam1,1.4425294523763884e-05,1.2306505,"[np.float32(2.0044084), np.float32(0.8483903)]",6.685295824757087e-05
+Arhgef12,5.177482485600521e-05,1.2184858,"[np.float32(1.4861581), np.float32(0.6329493)]",0.00017709451061350228
+Wdr33,1.8889233566654205e-05,1.2105358,"[np.float32(10.669129), np.float32(4.6045384)]",8.315707294872946e-05
+Ralgapa1,2.5836315845574668e-05,1.2053723,"[np.float32(4.2435403), np.float32(9.798527)]",0.00010911906760060993
+Clic4,1.0002017296718587e-05,1.2021452,"[np.float32(21.731308), np.float32(50.012737)]",4.99033982990946e-05
+Rpl36,9.117182385276679e-06,1.2007536,"[np.float32(0.06970579), np.float32(0.17321149)]",4.818714192896233e-05
+Anks6,0.008438796734545935,1.1995605,"[np.float32(4.275774), np.float32(1.85606)]",0.013599473462821227
+Hsp90aa1,6.465535379285421e-07,1.1989844,"[np.float32(0.22780727), np.float32(0.53595316)]",7.855205645872093e-06
+Cask,0.0002826589601999409,1.1951709,"[np.float32(6.0160427), np.float32(2.621782)]",0.0007459166636588003
+Ppp1r12a,1.0235328585872105e-06,1.1949607,"[np.float32(0.54872304), np.float32(1.2691327)]",9.820666555982927e-06
+Slc24a2,0.0001075626886317931,1.1902732,"[np.float32(7.7816014), np.float32(17.770119)]",0.0003257979454786641
+Tmod2,4.021765507150132e-07,1.1884322,"[np.float32(0.06517294), np.float32(0.16132283)]",5.725437318037143e-06
+Hmgcs1,1.3037503614165278e-06,1.1880723,"[np.float32(0.37502736), np.float32(0.15898421)]",1.1671372852680973e-05
+Taf13,5.434726376382299e-08,1.181986,"[np.float32(3.2932432), np.float32(7.4846916)]",1.6463489636801627e-06
+Hiat1,1.5680422432817526e-07,1.1788341,"[np.float32(0.08349196), np.float32(0.20165993)]",2.993680650183836e-06
+Zcrb1,5.894580511164047e-06,1.17433,"[np.float32(0.0130721275), np.float32(0.042071033)]",3.414476822411124e-05
+Rere,0.0006793201046469392,1.1700802,"[np.float32(4.94231), np.float32(11.133896)]",0.0015221651686160758
+Dnajc6,5.229264734355053e-07,1.1696187,"[np.float32(0.21331441), np.float32(0.49235082)]",6.828573732310423e-06
+Myh14,3.1658397795440794e-05,1.1570432,"[np.float32(15.054779), np.float32(33.58445)]",0.00012613985252110196
+Frmd5,2.9194291737751154e-06,1.1335922,"[np.float32(0.5613733), np.float32(0.2504202)]",1.9438619160616518e-05
+Tmsb10,0.002782119581751803,1.129408,"[np.float32(0.011876894), np.float32(0.0)]",0.00517429993783064
+Eri3,1.5181910165601159e-05,1.1276095,"[np.float32(0.06406745), np.float32(0.15183471)]",6.991268824117843e-05
+Phlpp1,4.9310140607918254e-05,1.1272334,"[np.float32(0.13049258), np.float32(0.2968912)]",0.00017022006102844107
+Ncam2,1.6115363519283386e-06,1.127054,"[np.float32(634.57996), np.float32(290.53683)]",1.3278801064567333e-05
+Atp5c1,0.004184275613092966,1.1222583,"[np.float32(0.06687568), np.float32(0.025314704)]",0.007156105733178189
+Lancl1,7.6385371808176e-09,1.1203877,"[np.float32(2.313906), np.float32(5.0422964)]",7.189633497653282e-07
+Gria4,0.0014013275718921803,1.1185039,"[np.float32(124.76427), np.float32(57.45744)]",0.0028195043897252187
+Ulk2,0.003171934219209558,1.117724,"[np.float32(15.443429), np.float32(33.524616)]",0.005619970572103299
+Nsd1,2.455800702565289e-08,1.1148915,"[np.float32(2.8480682), np.float32(6.1799674)]",1.1487007786249138e-06
+Ppp6r2,1.8752407002542601e-06,1.1144428,"[np.float32(1.6497427), np.float32(3.5835319)]",1.4379407172851316e-05
+Ust,3.6317776540847926e-05,1.1128486,"[np.float32(16.488094), np.float32(7.618391)]",0.0001332363919763264
+4930402H24Rik,0.0006313431052018562,1.1078624,"[np.float32(6.165731), np.float32(13.300309)]",0.0014300762104511777
+Upf3b,1.4527158049739289e-06,1.105508,"[np.float32(1.8421155), np.float32(0.85074997)]",1.2458603708644643e-05
+Usp42,0.0001583692541743297,1.1039169,"[np.float32(3.504067), np.float32(1.6249255)]",0.0004482736377612267
+Farsb,0.03062012365404909,1.1017385,"[np.float32(2.0924573), np.float32(4.5021496)]",0.042753918922929735
+Map2k1,0.0012912876164148752,1.101124,"[np.float32(0.36093432), np.float32(0.1629122)]",0.002626086011208947
+Gab1,1.3050147074107439e-05,1.0981467,"[np.float32(4.368065), np.float32(9.362539)]",6.212932614670487e-05
+Smarcc1,6.319341318934689e-07,1.0926574,"[np.float32(1.1038306), np.float32(2.3654277)]",7.806075762638965e-06
+Pcdh9,1.9657971689719553e-06,1.0907723,"[np.float32(120.20453), np.float32(56.431923)]",1.4890714587637767e-05
+D130020L05Rik,0.015222708750836315,1.0871764,"[np.float32(2.9111483), np.float32(1.364931)]",0.022987641705258067
+Atxn1l,0.00015780582168713837,1.0867524,"[np.float32(3.776052), np.float32(1.7725492)]",0.00044735559451005433
+Cep104,3.3774867781799095e-05,1.0854152,"[np.float32(2.1183515), np.float32(4.506332)]",0.00012638555523949223
+Me2,0.014357489717054271,1.0790142,"[np.float32(13.803021), np.float32(6.5284233)]",0.021910981452372382
+Eif2b3,4.1483191341053254e-05,1.0762937,"[np.float32(0.35411468), np.float32(0.75777656)]",0.00014616770432977522
+Fubp1,6.8893768139520465e-06,1.0743688,"[np.float32(3.7545211), np.float32(1.7776911)]",3.88253735509165e-05
+Ndufv3,1.7893495226629513e-06,1.0734769,"[np.float32(0.036883853), np.float32(0.012277914)]",1.4126046231655621e-05
+Trappc10,0.008867593550048663,1.0711497,"[np.float32(2.8408353), np.float32(5.9799104)]",0.014168460744783132
+Ufsp2,1.731597370154458e-08,1.0680617,"[np.float32(0.20578974), np.float32(0.44242793)]",1.0770375890496962e-06
+Phip,0.0038103015589435775,1.0639868,"[np.float32(1.0054581), np.float32(2.1130195)]",0.0066378717102266605
+Arrdc2,1.2317651524432555e-05,1.0488136,"[np.float32(19.606394), np.float32(9.471888)]",6.0173174940504724e-05
+Sec11c,1.0861943402256733e-07,1.0481703,"[np.float32(0.010679057), np.float32(0.0)]",2.3359420811060168e-06
+Sin3b,0.00813572555283482,1.0478351,"[np.float32(0.4914954), np.float32(1.0268043)]",0.013156389377142565
+Rps27l,6.924931124127905e-07,1.0470364,"[np.float32(0.021197015), np.float32(0.0544618)]",8.200345653951462e-06
+Ocel1,2.3179979828882838e-05,1.0296907,"[np.float32(2.8023596), np.float32(1.3675362)]",9.901767639232829e-05
+M6pr,0.0008855948950561586,1.0239979,"[np.float32(0.09482102), np.float32(0.2031584)]",0.0019447747049883483
+Mtdh,3.615174188236263e-05,1.0224143,"[np.float32(0.44537774), np.float32(0.21417871)]",0.0001331494272872057
+Fbxo30,0.002194963805877058,1.0127065,"[np.float32(1.3520564), np.float32(2.7382114)]",0.004199158773820016
+Wnk1,1.3190821131883899e-06,1.0042752,"[np.float32(0.49791193), np.float32(1.0088385)]",1.1687884596688241e-05
+Ggnbp2,4.4934963656747553e-07,1.0031248,"[np.float32(0.10496987), np.float32(0.04736056)]",6.274128134460797e-06
+Tnrc6b,0.003095639081357139,1.0022706,"[np.float32(2.9253943), np.float32(1.455389)]",0.005533002174311384
+Pak2,0.00030887291661652386,0.9970026,"[np.float32(0.7984517), np.float32(0.3950666)]",0.0008004172118968368
+Brd8,3.639662857559152e-05,0.98627466,"[np.float32(0.7091677), np.float32(0.35302114)]",0.0001332643680331345
+Acin1,7.149602128928409e-07,0.98387897,"[np.float32(0.764566), np.float32(0.38163486)]",8.226817921184841e-06
+Rnf20,0.00015359297951402458,0.9837883,"[np.float32(0.3142492), np.float32(0.63125193)]",0.00043607354274770863
+Mrps28,1.836105797020167e-06,0.98166484,"[np.float32(0.20451471), np.float32(0.4136114)]",1.4246448482471459e-05
+Zbtb38,0.0025435540441981013,0.96626645,"[np.float32(0.6680953), np.float32(1.3148476)]",0.004763753370064712
+Bop1,9.242377170549869e-08,0.965331,"[np.float32(1.2748233), np.float32(2.4986322)]",2.108839961719366e-06
+Uqcrc2,8.455002737052622e-07,0.9612598,"[np.float32(0.052256845), np.float32(0.021975629)]",9.091557540819227e-06
+Arfgap2,1.5795056569592882e-05,0.9554192,"[np.float32(0.52875024), np.float32(1.0347137)]",7.207939229684946e-05
+Snw1,2.8956752271220156e-06,0.9543045,"[np.float32(0.40799755), np.float32(0.20572448)]",1.93493155355189e-05
+Spata24,1.8440408407412987e-05,0.95013154,"[np.float32(4.545782), np.float32(2.3480058)]",8.234368527510667e-05
+Glrb,0.0011224664961034735,0.9444113,"[np.float32(0.8071414), np.float32(1.5625098)]",0.0023308932455156483
+Agap1,1.6115363519283386e-06,0.93672925,"[np.float32(1.8117338), np.float32(3.477133)]",1.3278801064567333e-05
+Igsf11,0.00037804065034239697,0.9183569,"[np.float32(1.3221556), np.float32(2.5077229)]",0.0009270171124385646
+Tacc1,1.180056386371999e-07,0.9162936,"[np.float32(5.3971486), np.float32(10.194698)]",2.4532061098911224e-06
+Chmp3,0.02431528821992974,0.91614825,"[np.float32(3.3796039), np.float32(1.7862254)]",0.03494155473078997
+Smarce1,0.0005542472094838378,0.8972078,"[np.float32(0.3960533), np.float32(0.20802012)]",0.0012834115457230947
+Csk,1.6618492681395346e-06,0.89155567,"[np.float32(0.6431887), np.float32(0.34208998)]",1.3518782524735084e-05
+Ndufv2,6.58766864086889e-07,0.8901493,"[np.float32(0.008533679), np.float32(0.0)]",7.951953565848835e-06
+Desi2,0.0042612856109829735,0.8852297,"[np.float32(2.478068), np.float32(4.5856075)]",0.00727451220634046
+Dixdc1,1.6106103690019597e-06,0.8817702,"[np.float32(0.4446747), np.float32(0.82779944)]",1.3278801064567333e-05
+Zdhhc14,3.220329114096639e-05,0.879524,"[np.float32(14.952434), np.float32(8.122782)]",0.00012613985252110196
+E2f3,0.0014197770653498107,0.87547857,"[np.float32(11.091973), np.float32(20.357864)]",0.0028502176923492443
+Sod2,0.008864960190792326,0.8750301,"[np.float32(0.20339562), np.float32(0.3813775)]",0.014168460744783132
+Cdc37l1,2.2627748497346577e-05,0.87076813,"[np.float32(8.524355), np.float32(4.6570597)]",9.754957935146415e-05
+Jakmip2,0.0005040864239047193,0.86488104,"[np.float32(1.1867406), np.float32(2.1694915)]",0.0011840918845677391
+Usp25,6.8858802376186405e-06,0.85644025,"[np.float32(2.1334593), np.float32(1.1738619)]",3.88253735509165e-05
+Tbcb,1.66497569613528e-05,0.8555787,"[np.float32(0.15756525), np.float32(0.082603864)]",7.56109108609007e-05
+Frg1,0.009273260789194136,0.85496306,"[np.float32(0.27300066), np.float32(0.5018668)]",0.01476618803113381
+Kif1a,4.46078255163895e-05,0.85096586,"[np.float32(0.012729626), np.float32(0.030997608)]",0.00015572736324640207
+Dip2a,3.369664589647217e-08,0.8481949,"[np.float32(0.27157617), np.float32(0.14640972)]",1.2609284894459887e-06
+Cpd,0.0006529615471051264,0.84123236,"[np.float32(0.49079335), np.float32(0.88721126)]",0.0014701456734460788
+Ppp2r3a,3.851879382990396e-06,0.8365147,"[np.float32(1.1709025), np.float32(0.65129924)]",2.4681049060188464e-05
+Prkdc,1.295671243078361e-05,0.8362326,"[np.float32(6.408824), np.float32(11.450051)]",6.200002291047605e-05
+Tmcc1,8.307437429333371e-06,0.8355784,"[np.float32(8.098566), np.float32(4.5337024)]",4.5052798348645617e-05
+Akap6,0.0006793201046469392,0.827493,"[np.float32(48.296867), np.float32(27.211287)]",0.0015221651686160758
+Srsf7,0.0006311527870070464,0.82101786,"[np.float32(0.15639868), np.float32(0.08418872)]",0.0014300762104511777
+Sema6d,0.0032993972880083983,0.8185135,"[np.float32(0.6172751), np.float32(1.0962548)]",0.005829051479140747
+Lpgat1,0.0012912876164148752,0.8178464,"[np.float32(1.3194909), np.float32(2.3335903)]",0.002626086011208947
+Phf20l1,0.0010401140173897634,0.81201255,"[np.float32(21.885624), np.float32(38.431248)]",0.002196084068900349
+Prickle2,2.273345426112617e-05,0.811598,"[np.float32(87.431595), np.float32(49.809887)]",9.755571771230977e-05
+Nhlrc2,1.2437351450488071e-05,0.8096915,"[np.float32(31.724768), np.float32(18.094807)]",6.044229756847579e-05
+Traf5,0.0004216551850009532,0.8095682,"[np.float32(61.01505), np.float32(34.808)]",0.00102059101052624
+Ralgps1,3.783709128699031e-07,0.80542415,"[np.float32(1.4130335), np.float32(2.476978)]",5.641791701635842e-06
+Ppm1a,0.0025102347375986025,0.8042902,"[np.float32(0.8518745), np.float32(0.48354703)]",0.004720250446278377
+Cfl2,1.4432128317978318e-05,0.8021741,"[np.float32(0.10644067), np.float32(0.19304071)]",6.685295824757087e-05
+Ints7,0.0021772098548719647,0.7950924,"[np.float32(6.3807774), np.float32(11.079204)]",0.004173729137771974
+Cdk19,1.9657971689719553e-06,0.794799,"[np.float32(5.4106336), np.float32(3.1145806)]",1.4890714587637767e-05
+Auts2,0.002900745680780796,0.7944834,"[np.float32(1.4304509), np.float32(0.8204914)]",0.00535764577368299
+Csnk1g3,4.7057645303013687e-07,0.7912938,"[np.float32(0.33754206), np.float32(0.59146523)]",6.466851516137395e-06
+Fam172a,6.465535379285421e-07,0.79073846,"[np.float32(3.969676), np.float32(2.2904444)]",7.855205645872093e-06
+Snrnp70,4.2859106851523715e-06,0.790323,"[np.float32(1.5443583), np.float32(2.678203)]",2.6729796306400293e-05
+Rb1cc1,1.0862274000283043e-05,0.7873856,"[np.float32(0.8181112), np.float32(1.4192735)]",5.362352151590916e-05
+Chd4,0.028653631950311856,0.7849865,"[np.float32(0.09719621), np.float32(0.05221211)]",0.04046968223568802
+Stx6,0.0018205263280346854,0.7782418,"[np.float32(0.40258196), np.float32(0.69759434)]",0.0035863895698192024
+Rnf19a,0.0020659106821978865,0.77656317,"[np.float32(2.6931748), np.float32(4.6206603)]",0.0039807609540599845
+Hint3,0.0018902741061898954,0.76463825,"[np.float32(1.6893412), np.float32(0.9902337)]",0.0037033537724411457
+Ptprk,0.0003813572020425553,0.76317215,"[np.float32(450.171), np.float32(265.23636)]",0.0009339258180911269
+Mt1,0.029145014491920612,0.75291246,"[np.float32(0.020566257), np.float32(0.008138153)]",0.04093868026605365
+Tmem208,0.00915324976644237,0.7493199,"[np.float32(0.26137465), np.float32(0.1514364)]",0.014599940590804498
+Herc4,5.977967902217967e-06,0.74868095,"[np.float32(10.147113), np.float32(17.05655)]",3.4520919583487084e-05
+Thoc7,0.00019523412440633232,0.7457874,"[np.float32(0.155439), np.float32(0.08865829)]",0.0005403595366335025
+Rnf130,0.021529843669568345,0.7455618,"[np.float32(0.38486275), np.float32(0.65203756)]",0.03132374611645597
+Snx16,2.158088565678986e-06,0.7442395,"[np.float32(0.9251456), np.float32(0.5482656)]",1.583444590739366e-05
+Ndufc2,0.008590933500524629,0.74103403,"[np.float32(0.0), np.float32(0.006713733)]",0.013808966133575242
+Creld1,2.0172826158179678e-05,0.7375134,"[np.float32(0.94708586), np.float32(0.5640335)]",8.811419533553273e-05
+Nkain2,1.0754806501004592e-06,0.7364204,"[np.float32(486.5739), np.float32(810.6568)]",1.0186902498551097e-05
+Rps10,0.0002426925211064065,0.735295,"[np.float32(0.0066473787), np.float32(0.0)]",0.0006590387619594871
+Btbd1,0.00014587516390461596,0.7254526,"[np.float32(0.49331576), np.float32(0.82219195)]",0.00041618693689921313
+Ndufs1,5.640169867156935e-06,0.7209317,"[np.float32(2.8401756), np.float32(1.7192172)]",3.318477302342964e-05
+Ndufs7,1.4790207826709285e-07,0.71702987,"[np.float32(0.0), np.float32(0.0064379447)]",2.852832870492069e-06
+Olfml1,1.253962121623908e-05,0.7170095,"[np.float32(43.46351), np.float32(26.43742)]",6.0616380341662276e-05
+Mgat3,5.1541556499549953e-05,0.71440893,"[np.float32(3.5452025), np.float32(2.1567352)]",0.00017675706870443558
+Cox6a1,1.0551463921036995e-08,0.7142085,"[np.float32(0.0), np.float32(0.0064058285)]",7.896715598504087e-07
+Purg,0.03054394432015581,0.7090837,"[np.float32(14.410173), np.float32(8.810943)]",0.04267940240702877
+Dnajc8,0.0003371910434611493,0.7060961,"[np.float32(0.060720645), np.float32(0.1053725)]",0.0008634823203219308
+Ptk2,0.0042612856109829735,0.70390254,"[np.float32(47.98013), np.float32(29.451586)]",0.00727451220634046
+Med13l,0.011620691967429927,0.70265293,"[np.float32(3.537713), np.float32(5.7638845)]",0.01813370698170258
+Pdia4,7.768260562106245e-07,0.69873,"[np.float32(0.44899613), np.float32(0.7349853)]",8.689541299910302e-06
+Rap1a,7.167136938285031e-07,0.69157654,"[np.float32(0.18668452), np.float32(0.30765486)]",8.226817921184841e-06
+Ube2h,0.0007242235829116513,0.68954796,"[np.float32(1.8932189), np.float32(3.0594697)]",0.0016150444858494632
+Tcea1,0.0005379471451268874,0.68790656,"[np.float32(2.585308), np.float32(4.1708965)]",0.0012518645628512516
+Bptf,0.012083000429864042,0.68751174,"[np.float32(0.4134996), np.float32(0.252961)]",0.018792430427494282
+Tmtc2,0.0010296903515885506,0.68345356,"[np.float32(74.311516), np.float32(46.267998)]",0.002196084068900349
+Anapc13,0.0006752771633587828,0.6790884,"[np.float32(0.21365558), np.float32(0.34810117)]",0.0015167389827662457
+Cuta,4.857357881028239e-08,0.6785234,"[np.float32(0.2774486), np.float32(0.16959915)]",1.5146860992339727e-06
+Rpl38,0.014410719654738464,0.67847687,"[np.float32(0.0060044914), np.float32(0.0)]",0.021935898098812415
+Ndufb9,0.0014734684415151896,0.6776952,"[np.float32(0.005995822), np.float32(0.0)]",0.002951669651043811
+Atrn,8.796804648493916e-07,0.6724828,"[np.float32(3.8890808), np.float32(2.4363847)]",9.143789720740064e-06
+Rab31,0.00014614367586466222,0.66271305,"[np.float32(6.7045813), np.float32(4.2315288)]",0.00041618693689921313
+Slc38a2,0.0004036264756617052,0.66040456,"[np.float32(1.7016864), np.float32(2.6953645)]",0.000982035287338167
+Rcan1,0.01735846239699096,0.65583956,"[np.float32(0.745032), np.float32(1.1795775)]",0.026044653684659247
+Pcbp2,0.0025435540441981013,0.6539296,"[np.float32(0.04993396), np.float32(0.02809084)]",0.004763753370064712
+Mon2,7.167136938285031e-07,0.6497726,"[np.float32(2.029993), np.float32(3.1905875)]",8.226817921184841e-06
+Chka,0.0006401191815987859,0.64758337,"[np.float32(277.34677), np.float32(177.04034)]",0.001442967456350998
+Dhx36,1.137496280954936e-07,0.64508384,"[np.float32(3.9944277), np.float32(6.252245)]",2.418472206439415e-06
+Bub3,0.014749415915283713,0.6390598,"[np.float32(0.91444343), np.float32(0.58361405)]",0.02233060496501717
+Gnal,2.5017526582351604e-05,0.6377635,"[np.float32(30.93466), np.float32(19.878397)]",0.0001063813459899542
+Spock3,1.1920124597767582e-06,0.63577443,"[np.float32(0.23890832), np.float32(0.3767467)]",1.0885700690600529e-05
+Cerk,0.0005633534384008689,0.63570243,"[np.float32(1.3924598), np.float32(2.1689932)]",0.001302885393384457
+Dpy30,0.0017569640681720606,0.6343628,"[np.float32(0.29929328), np.float32(0.47010112)]",0.0034749257627377647
+Snrnp27,0.00996905434606039,0.6326772,"[np.float32(0.059588555), np.float32(0.034883115)]",0.01572689770782377
+Scfd1,0.009928067841852838,0.63179487,"[np.float32(88.0917), np.float32(56.84846)]",0.015675455638908573
+Dab1,0.0010459352516103736,0.6308661,"[np.float32(44.586475), np.float32(69.047386)]",0.002196084068900349
+Sox8,2.950084557032733e-05,0.62807715,"[np.float32(0.28709725), np.float32(0.18223326)]",0.00012184565576618638
+Canx,6.911068153182339e-05,0.6251885,"[np.float32(0.202719), np.float32(0.31810045)]",0.00022967333063240064
+Bcap29,1.7833210764379933e-06,0.62202424,"[np.float32(3.302475), np.float32(2.1423092)]",1.4126046231655621e-05
+Yipf5,0.0005025165208644018,0.6214658,"[np.float32(2.5962846), np.float32(1.6841115)]",0.0011840918845677391
+1810037I17Rik,2.888070166682286e-05,0.62004864,"[np.float32(0.0053692698), np.float32(0.0)]",0.00011981328784617643
+Eef1e1,0.00028765731639182065,0.61640954,"[np.float32(0.25697938), np.float32(0.39929408)]",0.000754848301499434
+Sirt2,1.4675549836794717e-07,0.61526453,"[np.float32(0.060486805), np.float32(0.097974434)]",2.852832870492069e-06
+Gbas,0.00785423153365444,0.6144658,"[np.float32(1.1491868), np.float32(0.7471481)]",0.012767391137678068
+Siva1,0.007541742327590516,0.6104048,"[np.float32(0.35101262), np.float32(0.54115343)]",0.012280765791925026
+Faim2,1.3050147074107439e-05,0.60974675,"[np.float32(0.030935712), np.float32(0.016825652)]",6.212932614670487e-05
+Sltm,0.0006313431052018562,0.6086717,"[np.float32(3.2748706), np.float32(2.144219)]",0.0014300762104511777
+Cnot6,0.0009061165882517286,0.6047577,"[np.float32(168.8012), np.float32(256.7051)]",0.0019874467683380667
+Elavl3,4.555178365283781e-05,0.60411215,"[np.float32(0.04324338), np.float32(0.070932224)]",0.00015841521787074265
+Bsg,0.0009321310518117855,0.6034611,"[np.float32(0.0), np.float32(0.005193572)]",0.002037403268621321
+Tom1l2,0.003302402227626505,0.601673,"[np.float32(1.3960049), np.float32(0.91654223)]",0.005829051479140747
+Apmap,0.01544292364566594,0.59662545,"[np.float32(1.8208225), np.float32(1.200721)]",0.02330137914600079
+Smc6,0.010442255074433703,0.5952788,"[np.float32(0.056576487), np.float32(0.090581395)]",0.01639048594317572
+Tmed9,0.01936233704537368,0.59517246,"[np.float32(0.06767939), np.float32(0.041421063)]",0.02854762223159508
+Eif3b,0.02256881119690775,0.5907936,"[np.float32(0.24107864), np.float32(0.15671057)]",0.03263233829166492
+Rpl37,2.2592204400166824e-07,0.5869175,"[np.float32(0.23338933), np.float32(0.15203983)]",3.913890225251123e-06
+Bbip1,0.003092786831511809,0.57768345,"[np.float32(0.25715718), np.float32(0.16900566)]",0.005533002174311384
+Cdc42bpa,0.0019483999999567229,0.57716084,"[np.float32(1.3632698), np.float32(2.0387955)]",0.003793398959333016
+Brms1,0.0036355997299093498,0.57626903,"[np.float32(1.967658), np.float32(1.3164074)]",0.006375076939700462
+Exoc6b,5.894580511164047e-06,0.57601154,"[np.float32(0.59741443), np.float32(0.39746317)]",3.414476822411124e-05
+Pet100,3.832960263315993e-05,0.5590521,"[np.float32(2.8399792), np.float32(1.9244176)]",0.000136860088791302
+Stk19,6.814566297527465e-06,0.5589722,"[np.float32(0.054276768), np.float32(0.084693775)]",3.863652588689057e-05
+Eif4h,0.012775027860118563,0.55762076,"[np.float32(0.0047183987), np.float32(0.0)]",0.01972118574775729
+Plcl1,0.008746002602441185,0.55709064,"[np.float32(446.57864), np.float32(657.0555)]",0.013998093130168912
+Grb14,5.518621515306092e-07,0.55324036,"[np.float32(0.04854381), np.float32(0.029896889)]",7.072151270642259e-06
+Gm16124,0.00179474554027644,0.5527182,"[np.float32(5.6970267), np.float32(8.361334)]",0.00354590169573096
+Tceb1,0.0019075950768887501,0.55052567,"[np.float32(0.122760884), np.float32(0.08064532)]",0.003733379067843987
+Sec22a,1.02113399372681e-06,0.5417462,"[np.float32(1.745299), np.float32(2.5452473)]",9.820666555982927e-06
+BC031181,0.0002705266491074675,0.54140717,"[np.float32(0.0), np.float32(0.0045539136)]",0.0007199934003983949
+Myo1d,7.5135403421144775e-06,0.5347553,"[np.float32(26.83382), np.float32(38.878548)]",4.1838791607429124e-05
+Ddb1,0.0043490431561474885,0.53457385,"[np.float32(0.2689387), np.float32(0.39404666)]",0.007404058002868017
+Bin1,3.970425815366474e-05,0.53268325,"[np.float32(0.03273579), np.float32(0.01954188)]",0.00014122940495343484
+Qk,3.513987321322929e-05,0.52922857,"[np.float32(1.522988), np.float32(2.2023427)]",0.00013044980710704763
+Polr2a,0.001692543803607662,0.51996887,"[np.float32(34.81441), np.float32(49.925568)]",0.003365302291764013
+Usp54,0.03324366307009087,0.51426125,"[np.float32(0.9868227), np.float32(0.68792677)]",0.0462101735543388
+Smek1,4.196696496422201e-06,0.5088306,"[np.float32(8.388022), np.float32(5.8920617)]",2.6437774898336495e-05
+Rdx,0.0002497159473412224,0.50776297,"[np.float32(0.15470147), np.float32(0.105836555)]",0.0006761483899789105
+Zdhhc20,9.720387471583706e-05,0.49921986,"[np.float32(5.871137), np.float32(4.150841)]",0.00030463726900055465
+Lsamp,0.002379029709230995,0.49296424,"[np.float32(164.49437), np.float32(116.88082)]",0.004523541245905683
+Nbea,2.701486184153971e-05,0.49255943,"[np.float32(12.251369), np.float32(8.704928)]",0.00011332916256843228
+Tcf4,0.00012428998048786655,0.49216348,"[np.float32(0.17365323), np.float32(0.24831793)]",0.00036278713493416274
+Map2k2,0.00046909308519503393,0.49135804,"[np.float32(0.20622255), np.float32(0.14381102)]",0.0011109786865821625
+Smc3,0.0039698012569612025,0.49114627,"[np.float32(0.7027744), np.float32(0.49711016)]",0.006870951111724709
+Col19a1,9.117182385276679e-06,0.4904162,"[np.float32(2.868015), np.float32(2.0386279)]",4.818714192896233e-05
+Npat,0.013932732555790863,0.49020183,"[np.float32(1.2121663), np.float32(1.7067053)]",0.021297502133892733
+Hist1h2bc,7.321550369633291e-06,0.48576936,"[np.float32(0.0040033245), np.float32(0.0)]",4.089140519875787e-05
+Camkmt,0.0005050300145946436,0.48183957,"[np.float32(38.091377), np.float32(27.273022)]",0.0011840918845677391
+Hax1,0.012358376212928313,0.48077947,"[np.float32(0.415063), np.float32(0.29459605)]",0.019141160508600062
+Rock2,6.964538149758353e-05,0.4806597,"[np.float32(1.2834228), np.float32(0.9169313)]",0.00023022351374907913
+Zfp131,2.3645479369716673e-05,0.47969565,"[np.float32(1.1556259), np.float32(1.6154065)]",0.00010077606355521616
+Dock10,0.0005865339356368175,0.47725964,"[np.float32(40.438232), np.float32(29.045614)]",0.0013481633827720951
+Rtf1,3.8263904874047954e-05,0.47720957,"[np.float32(0.07419902), np.float32(0.10720913)]",0.000136860088791302
+Asphd2,0.0035201030923237477,0.46863025,"[np.float32(0.47033268), np.float32(0.3371126)]",0.006181093211416594
+Mag,6.060710477142683e-08,0.46432427,"[np.float32(0.35117945), np.float32(0.25178665)]",1.7276355417205883e-06
+Trpm7,0.0203500424280548,0.46288115,"[np.float32(12.814483), np.float32(9.294622)]",0.029956671426349744
+Hnrnph3,0.0004771372680512103,0.46173146,"[np.float32(0.22884111), np.float32(0.16342594)]",0.001128601553127452
+Tmeff2,2.394241541406704e-06,0.458055,"[np.float32(0.97543615), np.float32(0.70736504)]",1.6904248769705447e-05
+Golga4,0.017890982865191057,0.4576767,"[np.float32(2.027848), np.float32(2.7886345)]",0.026715106896067414
+Slc25a27,0.00012428998048786655,0.45542693,"[np.float32(6.942997), np.float32(9.5238695)]",0.00036278713493416274
+Rnf13,1.5772822806148767e-05,0.4522269,"[np.float32(0.25380707), np.float32(0.1828202)]",7.207939229684946e-05
+Sox10,0.005079448742901029,0.44832706,"[np.float32(1.7010295), np.float32(1.2440002)]",0.008531102870707205
+Flywch1,0.007394898938693638,0.44205788,"[np.float32(1.4627826), np.float32(1.9908351)]",0.01205213929816707
+Kif21a,0.004000404724161726,0.44145527,"[np.float32(5.1151705), np.float32(6.9498453)]",0.006898393768577502
+Srrm2,7.576095205311676e-05,0.4413246,"[np.float32(0.89001524), np.float32(0.65282357)]",0.00024397373716244657
+Map1b,0.000907151010240892,0.43498042,"[np.float32(0.852978), np.float32(0.6283481)]",0.0019874467683380667
+Fam13c,0.0010459352516103736,0.43084928,"[np.float32(3.446872), np.float32(2.554394)]",0.002196084068900349
+Enpp2,2.029410227201158e-07,0.4287088,"[np.float32(0.28426236), np.float32(0.38608548)]",3.5821005048050626e-06
+Dopey2,0.004829841309515238,0.4274094,"[np.float32(9.167503), np.float32(6.814353)]",0.008155806037999107
+Ntan1,0.017063484286706853,0.4267911,"[np.float32(0.045085818), np.float32(0.06404857)]",0.025622615650424174
+Fam213b,4.224958506037767e-06,0.421407,"[np.float32(0.17912196), np.float32(0.13121662)]",2.6526501224149875e-05
+Pbrm1,0.019359427814350013,0.4209962,"[np.float32(0.45897153), np.float32(0.6178833)]",0.02854762223159508
+Dnm3,5.8846402970858185e-05,0.4186996,"[np.float32(16.690334), np.float32(12.483498)]",0.00019909877026849125
+Mbnl2,8.796804648493916e-07,0.4185151,"[np.float32(2.8642237), np.float32(2.140478)]",9.143789720740064e-06
+Plekha1,0.00017792017887589218,0.4183006,"[np.float32(0.2731489), np.float32(0.36838672)]",0.0005013383353566178
+Mark3,0.013197695803462852,0.41769484,"[np.float32(2.5782506), np.float32(3.4473631)]",0.020240072826458195
+Mrpl38,0.013462275235949206,0.41698474,"[np.float32(0.7722563), np.float32(0.5759009)]",0.020612043344076077
+Ahcyl2,0.01936233704537368,0.4159555,"[np.float32(7.6532125), np.float32(5.733753)]",0.02854762223159508
+Spock1,0.0007448071531639356,0.4151593,"[np.float32(476.77765), np.float32(357.55054)]",0.0016530654609368015
+Rpl18,0.0060739934503817854,0.413433,"[np.float32(0.0043786275), np.float32(0.009150194)]",0.010119716603441069
+Ndfip1,0.0019483999999567229,0.40899014,"[np.float32(12.54164), np.float32(16.655516)]",0.003793398959333016
+Gprc5b,3.2089102940775062e-06,0.40539378,"[np.float32(2.849497), np.float32(2.1490066)]",2.10662145972597e-05
+Cetn3,0.018347767300931035,0.40525278,"[np.float32(0.050408497), np.float32(0.035614695)]",0.027227526234487136
+Sec23a,0.0007823996532082963,0.4029102,"[np.float32(2.5512629), np.float32(1.9271628)]",0.001732390238050559
+Rpsa,1.8319312080493019e-06,0.4023293,"[np.float32(0.004392124), np.float32(0.009021207)]",1.4246448482471459e-05
+Cnp,0.02230621953501107,0.3989601,"[np.float32(0.6869586), np.float32(0.9089798)]",0.032277599961334655
+Rexo2,0.007394898938693638,0.39322457,"[np.float32(0.053482387), np.float32(0.07337304)]",0.01205213929816707
+Ralgds,4.5925073013268545e-05,0.38855696,"[np.float32(0.0893699), np.float32(0.065908)]",0.00015941709018149435
+Setd7,0.006970576073155033,0.3866985,"[np.float32(6.834324), np.float32(8.938256)]",0.011420269555930881
+Psenen,0.015140310886460397,0.385713,"[np.float32(0.038632985), np.float32(0.02722372)]",0.022881681477033445
+Nova1,8.53742527379428e-05,0.38505584,"[np.float32(1.4590132), np.float32(1.1148959)]",0.00027027957169660066
+Fcor,0.02788963019070951,0.38351235,"[np.float32(0.35972592), np.float32(0.47231263)]",0.039531437944558705
+Sfr1,0.0040227368760927,0.3829869,"[np.float32(0.0), np.float32(0.003040389)]",0.006911423962506375
+Zadh2,0.008317076670324755,0.3794955,"[np.float32(2.159408), np.float32(1.6576378)]",0.013426445599808125
+Rabif,0.00026007080561931545,0.37776762,"[np.float32(0.40427428), np.float32(0.5282789)]",0.0006961265769867514
+Tns3,0.001382743357740836,0.37005505,"[np.float32(1.6725304), np.float32(2.164506)]",0.002796878726846599
+Dnaja3,1.9586536712631517e-05,0.36686993,"[np.float32(0.36778036), np.float32(0.4771674)]",8.582297468228001e-05
+Gatm,1.458275901760116e-06,0.3655255,"[np.float32(0.7924253), np.float32(0.61283135)]",1.2458603708644643e-05
+Pex5l,9.09915462422503e-06,0.36410165,"[np.float32(2.8152404), np.float32(2.1850777)]",4.818714192896233e-05
+Slc25a12,0.0018209888248681145,0.3630146,"[np.float32(1.496879), np.float32(1.1616559)]",0.0035863895698192024
+Dync1i2,0.022695647405026578,0.35816035,"[np.float32(1.8729154), np.float32(1.4589729)]",0.03279039096123917
+Msra,0.00043472698193462863,0.35807234,"[np.float32(2.6234298), np.float32(3.365299)]",0.0010454681017990875
+Sgip1,0.0019483999999567229,0.35587168,"[np.float32(10.955874), np.float32(14.023672)]",0.003793398959333016
+Mapk6,0.003934978662891463,0.35396212,"[np.float32(14.171626), np.float32(18.115051)]",0.00682963365331162
+Acap2,0.02651678197825236,0.34731412,"[np.float32(3.493893), np.float32(4.447617)]",0.03778590942978688
+Cdh11,0.03582230309780359,0.3452676,"[np.float32(3.4606845), np.float32(2.7219908)]",0.04946385911143212
+Prkca,3.840440637204862e-07,0.34238523,"[np.float32(14.345695), np.float32(11.312857)]",5.641791701635842e-06
+Edil3,0.02651315464984209,0.34144542,"[np.float32(2.3195148), np.float32(2.9415543)]",0.03778590942978688
+Hs6st3,9.324416130651365e-06,0.33695242,"[np.float32(34.042892), np.float32(43.001717)]",4.859605175612452e-05
+Epha4,0.006965150704317949,0.32941478,"[np.float32(3.2423007), np.float32(2.5783737)]",0.011420269555930881
+Ddr1,0.023912485039792826,0.3262723,"[np.float32(1.6738338), np.float32(2.1011398)]",0.0343891310603016
+Smchd1,0.014751805310935982,0.32577565,"[np.float32(1.5621858), np.float32(1.2443987)]",0.02233060496501717
+Atp5f1,4.44685136935567e-06,0.32436913,"[np.float32(0.002521169), np.float32(0.0)]",2.7013178285923568e-05
+Map7,8.94889365992015e-05,0.32303166,"[np.float32(1.8431376), np.float32(1.4713765)]",0.00028187508480994277
+Rps24,0.0030949258711904398,0.31586403,"[np.float32(0.009131272), np.float32(0.0053694854)]",0.005533002174311384
+Mettl7a1,0.0012348912216279566,0.3148378,"[np.float32(0.25483713), np.float32(0.31942344)]",0.0025334226706863012
+Exosc1,0.0019464445291199534,0.3109375,"[np.float32(0.5366035), np.float32(0.66806906)]",0.003793398959333016
+Rps27,7.992164105046774e-05,0.30950868,"[np.float32(0.0023928569), np.float32(0.0)]",0.0002556126331716669
+Slc35b1,0.0005056597625706166,0.30903468,"[np.float32(0.32453343), np.float32(0.40444627)]",0.0011840918845677391
+Dlg2,0.029347001790005368,0.30740985,"[np.float32(203.97813), np.float32(252.42204)]",0.04115156947276314
+Mapt,0.01835056685285317,0.30616337,"[np.float32(0.101442106), np.float32(0.08013324)]",0.027227526234487136
+Selk,2.5034680355391285e-06,0.30223185,"[np.float32(0.0023305048), np.float32(0.0)]",1.7477569755573544e-05
+Aldoa,4.7485256820759617e-07,0.30074927,"[np.float32(0.002317839), np.float32(0.0)]",6.466851516137395e-06
+Dpysl2,0.029362557587460605,0.29726055,"[np.float32(2.5367317), np.float32(2.0625205)]",0.04115156947276314
+Tbc1d12,0.001867105013168261,0.29627994,"[np.float32(3.117928), np.float32(3.831014)]",0.0036694889491993873
+Rab18,5.473979277381247e-05,0.2921438,"[np.float32(0.07409416), np.float32(0.092969805)]",0.0001862148223269148
+Naa40,0.00989252356271167,0.28607023,"[np.float32(24.77166), np.float32(20.314257)]",0.01564574098548904
+Bckdha,0.011069840886810399,0.2852529,"[np.float32(1.3596083), np.float32(1.1138974)]",0.017346459212078943
+Ptprd,0.00013480018049723128,0.27902064,"[np.float32(27.795084), np.float32(22.905567)]",0.0003868268983287112
+Pfdn5,0.0005089469077693317,0.27529788,"[np.float32(0.002038486), np.float32(0.004569504)]",0.0011902995805455245
+Pacsin1,0.0030360725367511547,0.27015385,"[np.float32(1.1058782), np.float32(1.3356782)]",0.005533002174311384
+Gna12,0.0005056597625706166,0.26654863,"[np.float32(1.3139901), np.float32(1.0906408)]",0.0011840918845677391
+Dgka,1.822767376856342e-05,0.2650829,"[np.float32(7.244), np.float32(6.026423)]",8.173605811544128e-05
+Clpp,0.019304185208024252,0.26356867,"[np.float32(0.6422994), np.float32(0.5333816)]",0.02854762223159508
+Tecpr2,0.01812660633801859,0.26260242,"[np.float32(3.66413), np.float32(4.397636)]",0.02695936443436628
+Mtf2,0.002388153941938461,0.26064378,"[np.float32(4.7282867), np.float32(3.945121)]",0.004536280228798843
+Myl6,0.0005056597625706166,0.25320765,"[np.float32(2.1242359), np.float32(1.7806855)]",0.0011840918845677391
+Map4k4,0.0037507762886049996,0.24482358,"[np.float32(0.83842653), np.float32(0.9953411)]",0.006558600407457901
+Map4k5,0.028589314969223536,0.23136255,"[np.float32(1.5959494), np.float32(1.8752934)]",0.040461882229513794
+Fam174a,0.00016186212355276167,0.22853014,"[np.float32(0.024362909), np.float32(0.030260978)]",0.0004574683280471557
+Rps23,3.3853689754298112e-06,0.22811908,"[np.float32(0.0), np.float32(0.0017130679)]",2.2146941793808312e-05
+Mettl9,0.02631390998341849,0.21843877,"[np.float32(0.1011618), np.float32(0.085543014)]",0.037554024087700984
+Nsmce2,0.009368342563661583,0.21369947,"[np.float32(4.3458185), np.float32(5.0412602)]",0.014892242087179968
+Gskip,0.002541729671958354,0.21250543,"[np.float32(1.4706321), np.float32(1.2678405)]",0.004763753370064712
+Rpn2,0.01763221858711176,0.21158028,"[np.float32(0.06472263), np.float32(0.05452977)]",0.02641303520935637
+Sept7,0.0017012751863829272,0.21073137,"[np.float32(0.1440932), np.float32(0.1231518)]",0.0033790720527839243
+Ank3,0.027698282744683795,0.2089968,"[np.float32(0.0883393), np.float32(0.075077124)]",0.03934964845505192
+Sept4,0.03493281905772702,0.20421799,"[np.float32(0.043536123), np.float32(0.051676918)]",0.048342680811395894
+Sec62,0.025185509080379646,0.19228709,"[np.float32(0.29669696), np.float32(0.25842643)]",0.0360812308494566
+Eny2,0.029319292006317693,0.18605196,"[np.float32(0.45089048), np.float32(0.5143303)]",0.04115156947276314
+Tmem258,2.950084557032733e-05,0.18534277,"[np.float32(0.35403174), np.float32(0.40393582)]",0.00012184565576618638
+Pip4k2a,0.02389897967664664,0.18139297,"[np.float32(4.726589), np.float32(5.3611894)]",0.0343891310603016
+Ash1l,0.034122311447128795,0.17869328,"[np.float32(1.4917879), np.float32(1.316834)]",0.04739632124541795
+Ywhae,7.038112453546371e-09,0.17816348,"[np.float32(0.0), np.float32(0.0013144268)]",7.189633497653282e-07
+Ybx1,9.87338375454933e-06,0.17455147,"[np.float32(0.0), np.float32(0.0012861352)]",4.963651573266607e-05
+Rps6ka5,0.003951504536793218,0.17123163,"[np.float32(3.4951162), np.float32(3.9368289)]",0.00685196013747925
+Taldo1,2.888070166682286e-05,0.16811721,"[np.float32(0.0012359113), np.float32(0.0)]",0.00011981328784617643
+Ppp1r14a,0.004000404724161726,0.16423793,"[np.float32(0.26529595), np.float32(0.23567404)]",0.006898393768577502
+Tubb4a,0.03584897128556684,0.16263811,"[np.float32(0.8435173), np.float32(0.7525238)]",0.04946417793163389
+Atp6v0b,4.869035285401437e-06,0.1510328,"[np.float32(0.0011036409), np.float32(0.0)]",2.9198605830083617e-05
+Shfm1,0.02847238256592584,0.14993484,"[np.float32(0.01863136), np.float32(0.015805192)]",0.040326894610785195
+Stmn4,0.0308814171797196,0.1450633,"[np.float32(0.024846068), np.float32(0.028532056)]",0.043086600703397
+Itm2b,0.00014592883683855231,0.13888048,"[np.float32(0.0013967663), np.float32(0.002548413)]",0.00041618693689921313
+Kif1b,0.0004036264756617052,0.13784997,"[np.float32(0.35609117), np.float32(0.32273024)]",0.000982035287338167
+Rps16,4.097803966904872e-05,0.13288783,"[np.float32(0.0009648633), np.float32(0.0)]",0.00014493367149487742
+Atp5d,8.345077808243944e-05,0.13171647,"[np.float32(0.0), np.float32(0.0009559641)]",0.00026508727638751135
+Rps15,0.003135690710080394,0.12720059,"[np.float32(0.0), np.float32(0.0009217242)]",0.00556102115503357
+Glo1,0.026212671987903204,0.11805598,"[np.float32(0.00443845), np.float32(0.005669638)]",0.0374380986941732
+Sdhb,0.0026075237001597588,0.11760934,"[np.float32(0.006836562), np.float32(0.00551849)]",0.004878676842998909
+Qtrt1,0.03242146589557971,0.109891854,"[np.float32(6.564367), np.float32(6.0821867)]",0.04513434724005181
+Rpl26,0.0025380833361647957,0.10129815,"[np.float32(0.0021280085), np.float32(0.00301018)]",0.004763753370064712
+Rps11,0.00029646195302058067,0.094535045,"[np.float32(0.005144401), np.float32(0.0061699995)]",0.00077577666307903
+Ppia,0.00043813953156452454,0.073848516,"[np.float32(0.0004829155), np.float32(0.0010334861)]",0.0010509731584066992
+Rpl14,0.014751805310935982,0.07161522,"[np.float32(0.00087910704), np.float32(0.0014327725)]",0.02233060496501717
+Uqcrq,0.029975382171374937,0.07129377,"[np.float32(0.0056029633), np.float32(0.006393385)]",0.041978997037906064
+Rps14,9.533512093844468e-10,0.06581547,"[np.float32(0.0), np.float32(0.00046676362)]",4.1043809418180814e-07
+Rpl17,0.001649317241150576,0.064005904,"[np.float32(0.0036231857), np.float32(0.003031998)]",0.0032828431470135404
+Rps7,0.0035216704240353227,0.062862866,"[np.float32(0.000919682), np.float32(0.0014060054)]",0.006181093211416594
+Gpx4,5.172956244111671e-07,0.06230707,"[np.float32(0.00044134152), np.float32(0.0)]",6.8159162906569976e-06
+Syt11,2.7142334744874694e-05,0.059192937,"[np.float32(0.0015267312), np.float32(0.0010633676)]",0.00011360919084487819
+Rpl3,3.995483952230537e-08,0.04711226,"[np.float32(0.0005105827), np.float32(0.00017289507)]",1.3411526286821638e-06
+Synpr,0.026958382298088703,0.04364429,"[np.float32(2.833416), np.float32(2.9207492)]",0.03838594617939419
+Ptma,5.476164402499891e-08,0.041970737,"[np.float32(0.0), np.float32(0.0002951919)]",1.6463489636801627e-06
+Sepw1,0.00012709947874027467,0.039016414,"[np.float32(0.0002741307), np.float32(0.0)]",0.0003675473334204852
+Rps6,0.0005112065804630197,0.024007415,"[np.float32(0.0003688241), np.float32(0.0005428123)]",0.001194091775338714
+Calm1,1.4245773385624318e-06,0.019581567,"[np.float32(0.0), np.float32(0.00013665394)]",1.2339741668751435e-05
+Ubb,2.7289317104968944e-06,0.010455714,"[np.float32(0.0), np.float32(7.273655e-05)]",1.8702678499412783e-05
+Tmsb4x,1.7911433489974328e-08,0.0065661236,"[np.float32(4.5616605e-05), np.float32(0.0)]",1.0770375890496962e-06
+Fth1,7.941804181104552e-07,0.001954634,"[np.float32(4.6010275e-05), np.float32(3.240893e-05)]",8.689541299910302e-06
+Atp6v0a2,0.0003057483411444523,1.7198263e-07,"[np.float32(6.4417176), np.float32(6.4417186)]",0.0007945210365017642
+Pabpc1,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+6030458C11Rik,0.006862355576044556,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01128248443126482
+Pdzd2,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Grasp,0.005379731779245794,0.0,"[np.float32(0.0), np.float32(0.0)]",0.009003111054533882
+Sept3,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Rbx1,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Gda,0.00010166607323071416,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003149291771765997
+Snx32,0.001967902586694143,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0038154878131655356
+Garem,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Nudcd1,3.18237465667597e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Mex3c,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Slc6a15,0.014420713341282348,0.0,"[np.float32(0.0), np.float32(0.0)]",0.021935898098812415
+Cep290,0.006862355576044556,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01128248443126482
+S100b,0.008656288371426955,0.0,"[np.float32(0.0), np.float32(0.0)]",0.013878248108774492
+Snrpd3,0.028789496021219,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04046968223568802
+Papd5,0.028789496021219,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04046968223568802
+Nr3c2,0.004037202864989172,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0069275287275154755
+Atp6v1b2,0.012200808738364486,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01891657821265176
+Celf4,0.003956823922559368,0.0,"[np.float32(0.0), np.float32(0.0)]",0.006854831073248684
+Atrnl1,0.008046087285584192,0.0,"[np.float32(0.0), np.float32(0.0)]",0.013033964771712574
+Dlgap2,0.021356712076975704,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Mob2,0.011208856712637523,0.0,"[np.float32(0.0), np.float32(0.0)]",0.017520276448909612
+Bet1l,0.0010306021312696373,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Nipsnap1,0.0010306021312696373,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Npm3,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Usp14,0.0013929313172250989,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0028144432986265226
+Kcnq3,0.0006625170871353722,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0014898671514787035
+Sorbs2,0.001967902586694143,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0038154878131655356
+Tnfrsf19,0.012200808738364486,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01891657821265176
+Slc7a8,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Nrg3,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Gm13703,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Ubr3,0.01260911313884519,0.0,"[np.float32(0.0), np.float32(0.0)]",0.019513358711976306
+Gpr107,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Med27,0.005076307429177853,0.0,"[np.float32(0.0), np.float32(0.0)]",0.008531102870707205
+Olfm1,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Edf1,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Cog7,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Usmg5,0.028789496021219,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04046968223568802
+Rapgefl1,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Heatr6,0.0027940653203496835,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005181066614840692
+Zfp207,0.002645745390606477,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004929043380240073
+Zzef1,0.018068311215826586,0.0,"[np.float32(0.0), np.float32(0.0)]",0.026894041594917695
+Stx8,0.0008234723283676454,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0018211781635648515
+Specc1,0.003976982706506929,0.0,"[np.float32(0.0), np.float32(0.0)]",0.006877019079366418
+Zfp787,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Fam175b,0.00012635079900818279,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003665152634795504
+Gdpd3,0.0022115968498836193,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004213745118260948
+Gfra1,0.021320201608024166,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Add3,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Lrp1,0.013180577136465338,0.0,"[np.float32(0.0), np.float32(0.0)]",0.020240072826458195
+Tbk1,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Atcay,0.001967902586694143,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0038154878131655356
+Cabin1,0.01029297809865442,0.0,"[np.float32(0.0), np.float32(0.0)]",0.016169741412747622
+Rnf217,0.0029180265174542,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0053789434622234554
+Tpd52l1,0.003336055816859082,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0058773638732046544
+Hars,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Smg1,0.001399314721599373,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0028195043897252187
+Fzd3,0.0037747897819248766,0.0,"[np.float32(0.0), np.float32(0.0)]",0.006588039952903565
+St5,0.0004555786192145125,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0010886176201153933
+Crtc3,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Lrrc28,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Klf13,0.004337255918291004,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0073907156859038875
+Gabra5,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Sult2b1,0.003090542676951182,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Fcgrt,0.0031142891921176813,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Dock9,0.000938022942262496,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002043976089034129
+Akap11,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Nefm,0.003064285322313353,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Galnt18,0.0003758354251119494,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0009228190031292091
+Dennd1b,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Fam162a,0.022120779734144416,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03205885273631619
+Kalrn,0.0004303602380243199,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0010376340275045136
+Gpc4,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Abcc5,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Zdhhc8,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Parn,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Grin2a,0.021356712076975704,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Arpp21,0.000938022942262496,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002043976089034129
+Crebbp,0.011208856712637523,0.0,"[np.float32(0.0), np.float32(0.0)]",0.017520276448909612
+Mettl1,0.021356712076975704,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Cd47,0.0022115968498836193,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004213745118260948
+Rtn4r,0.01311851064122576,0.0,"[np.float32(0.0), np.float32(0.0)]",0.02020142667467769
+Sh3gl1,0.0024590874304622245,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004628724931986742
+Klhdc3,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Cd2ap,0.012772197815350909,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01972118574775729
+Mthfd1l,0.0010505967012335625,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Ppp1r14c,0.004656015663689074,0.0,"[np.float32(0.0), np.float32(0.0)]",0.007890765676415088
+Smyd2,0.003064285322313353,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Atp1a2,0.01318748159958035,0.0,"[np.float32(0.0), np.float32(0.0)]",0.020240072826458195
+Ddr2,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Morc3,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Ncl,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Sphkap,0.0006293343038983513,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0014300762104511777
+Wdr12,0.017671165172868885,0.0,"[np.float32(0.0), np.float32(0.0)]",0.026450200030750146
+Clk1,0.00045932550900234045,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0010961709532441059
+Gm16894,0.00044317287028369367,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0010616855829715633
+Rev1,0.00031263238092518194,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008079215258439439
+2010300C02Rik,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Arfgef1,0.009904108096180085,0.0,"[np.float32(0.0), np.float32(0.0)]",0.015650832979689982
+Setd2,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Vprbp,0.00676388418937278,0.0,"[np.float32(0.0), np.float32(0.0)]",0.011189414074550373
+Tulp4,0.006862355576044556,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01128248443126482
+Senp6,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Rfx7,0.002645745390606477,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004929043380240073
+Rab11fip3,0.014420713341282348,0.0,"[np.float32(0.0), np.float32(0.0)]",0.021935898098812415
+Spast,0.00012635079900818279,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003665152634795504
+Fsd1,0.028789496021219,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04046968223568802
+Gabbr1,0.002044577572357733,0.0,"[np.float32(0.0), np.float32(0.0)]",0.003947786004005489
+Ppp1r10,0.0010122568481724444,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0021945916140563657
+Zfp414,0.007290908354676091,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01190339400663086
+BC004004,0.00046331642904799366,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0011000825364832437
+Smoc2,0.0031063615886952212,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Cyb5r4,0.00036971238090482977,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0009113726807285066
+Nfix,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Zswim4,0.00010760354023035953,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Cdkn2aip,0.0023121746933627034,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004400894050133894
+Slc25a4,0.022120779734144416,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03205885273631619
+Ddhd2,0.03454069547885263,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04783541172533921
+Plekha2,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Fam155a,0.008648895017980732,0.0,"[np.float32(0.0), np.float32(0.0)]",0.013878248108774492
+Ap1g1,0.0013523479301245187,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00274132500245176
+Sntb2,0.0002799177335442807,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0007407723896200129
+Rltpr,3.286662861799641e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Ppp1r12b,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Grm1,0.002645745390606477,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004929043380240073
+Cs,0.018068311215826586,0.0,"[np.float32(0.0), np.float32(0.0)]",0.026894041594917695
+Ccdc148,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Tnks2,0.0251585961726518,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03607029382301266
+Zfand5,0.0009384155320578925,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002043976089034129
+Rcor2,0.00010892377001882365,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Ctdp1,0.00010166607323071416,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003149291771765997
+Mapk4,0.019346260291701698,0.0,"[np.float32(0.0), np.float32(0.0)]",0.02854762223159508
+Fbxo38,0.00022387948371356946,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0006115014803329758
+Ccdc112,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Coq9,0.008046087285584192,0.0,"[np.float32(0.0), np.float32(0.0)]",0.013033964771712574
+Cadm1,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Thy1,3.251606514895865e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Tmem218,0.003064285322313353,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Prdm10,0.00010994761901595805,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Mrpl4,0.0031142891921176813,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Cwc15,0.004387212318520982,0.0,"[np.float32(0.0), np.float32(0.0)]",0.007441953080646198
+Trpc6,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Abcb10,0.0012025408813730908,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0024779228954284723
+Ubxn4,0.014555397956887534,0.0,"[np.float32(0.0), np.float32(0.0)]",0.022104829202383585
+Ist1,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Asna1,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+1810041L15Rik,0.0008326399498450425,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0018349462263369547
+Desi1,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+St13,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Ago2,0.001402970917602447,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0028195043897252187
+Nedd4l,0.005037132328358919,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00848287541526511
+Cul2,0.00046331642904799366,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0011000825364832437
+Slc8a1,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Cebpz,0.00022387948371356946,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0006115014803329758
+Slc7a6os,0.00156299881841965,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0031243277663068007
+Cmtm4,0.011122148132248844,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01741384029743731
+Csnk2a2,0.0027940653203496835,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005181066614840692
+Slc2a13,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Sez6l,0.008255161778906102,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01333800318508922
+Ulk1,0.0031063615886952212,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Fry,0.00012635079900818279,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003665152634795504
+Pomp,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Trrap,3.351160950598713e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Mdh2,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Gm10419,0.00034843136285467427,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+BC005561,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Hdac1,0.028789496021219,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04046968223568802
+Zbtb8a,0.00010166607323071416,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003149291771765997
+Pygb,0.0029314103737611377,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005379816611527165
+Nasp,0.00018758978010136824,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0005238514605517313
+Itgb3bp,0.009319801599796621,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01482767754525466
+Psip1,0.006051530512618354,0.0,"[np.float32(0.0), np.float32(0.0)]",0.010091277708653245
+Brinp1,0.004680750570464921,0.0,"[np.float32(0.0), np.float32(0.0)]",0.007925506169538342
+Ctnnal1,0.0006183509169962593,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0014108958118292697
+Alg2,0.021356712076975704,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Gabbr2,0.017740186492948676,0.0,"[np.float32(0.0), np.float32(0.0)]",0.02651109339321643
+Cntfr,0.021356712076975704,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Kif21b,0.00046309407254599113,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0011000825364832437
+Ankrd6,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+C77080,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Ttc37,0.006862355576044556,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01128248443126482
+B230219D22Rik,0.0010306021312696373,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Sfxn1,0.0012855509949137116,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0026258361479078104
+Secisbp2,0.008046087285584192,0.0,"[np.float32(0.0), np.float32(0.0)]",0.013033964771712574
+Cap2,0.017740186492948676,0.0,"[np.float32(0.0), np.float32(0.0)]",0.02651109339321643
+Smim13,0.03454069547885263,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04783541172533921
+Pak1ip1,0.00010994761901595805,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+D130043K22Rik,0.021356712076975704,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Lyst,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Adarb2,0.0020163752208842136,0.0,"[np.float32(0.0), np.float32(0.0)]",0.003901383700387139
+Svop,0.004387212318520982,0.0,"[np.float32(0.0), np.float32(0.0)]",0.007441953080646198
+Gm26881,0.0003463512073228454,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Mmp16,0.008648895017980732,0.0,"[np.float32(0.0), np.float32(0.0)]",0.013878248108774492
+Gem,0.0012302391357267056,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002526649201915111
+Fpgt,0.0010515163281560693,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Sipa1l1,0.027269050306597653,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03876929568665973
+Atl1,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Lrfn5,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Dock4,0.0011334362946189085,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0023484599194152577
+Ankmy2,3.33170820268816e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Nbas,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Brf1,0.006862355576044556,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01128248443126482
+Prex2,0.0010306021312696373,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Fgf13,3.33170820268816e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Snap91,0.01326977611149418,0.0,"[np.float32(0.0), np.float32(0.0)]",0.020333948488620485
+Dis3l2,0.0024590874304622245,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004628724931986742
+Unc80,0.01318748159958035,0.0,"[np.float32(0.0), np.float32(0.0)]",0.020240072826458195
+Trnp1,0.0007695887487187754,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0017060433043279961
+Tmem186,0.004384621829619794,0.0,"[np.float32(0.0), np.float32(0.0)]",0.007441953080646198
+Btg3,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Lingo2,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Wdr59,0.0010306021312696373,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Klhl32,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Atm,0.00042731084167567867,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0010329439079782878
+Pts,0.006862355576044556,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01128248443126482
+Zbtb16,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Ccdc84,0.007561894087253307,0.0,"[np.float32(0.0), np.float32(0.0)]",0.012302872901957336
+Grik4,0.03190521946649287,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04444874580923914
+Keap1,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Pam,0.0065999527137590224,0.0,"[np.float32(0.0), np.float32(0.0)]",0.010937565569037317
+Hdlbp,0.00010994761901595805,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Chic1,0.03454069547885263,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04783541172533921
+Rab33a,0.023191028922567955,0.0,"[np.float32(0.0), np.float32(0.0)]",0.033428671120280924
+Scaper,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Plekhg5,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Zbtb17,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Srsf10,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Mrps15,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Scmh1,0.0024590874304622245,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004628724931986742
+Mrpl1,3.357664955978946e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Dicer1,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Lgmn,0.00022387948371356946,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0006115014803329758
+Ttc7b,0.004297065413799161,0.0,"[np.float32(0.0), np.float32(0.0)]",0.007328905550791459
+Dcaf5,0.021356712076975704,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Atp6v1h,0.005929368448655583,0.0,"[np.float32(0.0), np.float32(0.0)]",0.009905221756638032
+Rtn1,0.0011334362946189085,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0023484599194152577
+Trim9,0.014139254736492779,0.0,"[np.float32(0.0), np.float32(0.0)]",0.02159554743834938
+Nemf,0.018068311215826586,0.0,"[np.float32(0.0), np.float32(0.0)]",0.026894041594917695
+Strn3,0.005037132328358919,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00848287541526511
+Prkd1,0.0027940653203496835,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005181066614840692
+Nudc,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Uba1,0.00046331642904799366,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0011000825364832437
+Atpif1,0.009651007649809314,0.0,"[np.float32(0.0), np.float32(0.0)]",0.015289614998131437
+Kpna6,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Ofd1,0.002898020007630967,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00535764577368299
+Wdr89,0.01908557079776706,0.0,"[np.float32(0.0), np.float32(0.0)]",0.028273240667159277
+Herc2,0.021356712076975704,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Slc17a7,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Kcnc3,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Arhgef1,0.019107499358218653,0.0,"[np.float32(0.0), np.float32(0.0)]",0.02828333172407207
+Smim17,0.00010166607323071416,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003149291771765997
+Lrp6,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Cenpv,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Zfp672,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Anxa6,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Rap2a,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Mef2c,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Elf1,0.0010232567679439384,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Fbn1,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Dnajc17,0.0004303602380243199,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0010376340275045136
+Depdc7,0.0021688350337659887,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004166211856443701
+Hipk3,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+2700094K13Rik,0.01318748159958035,0.0,"[np.float32(0.0), np.float32(0.0)]",0.020240072826458195
+Cwc22,0.002438053591661449,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004614941111265526
+Rbms1,0.021358472186392776,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+Iqgap2,0.0022115968498836193,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004213745118260948
+Xrcc4,0.006633764640250228,0.0,"[np.float32(0.0), np.float32(0.0)]",0.010983870479564757
+Lmo7,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Golga1,0.0012891056263238771,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002626086011208947
+Strbp,0.0029314103737611377,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005379816611527165
+Rabepk,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Gapvd1,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Ntng2,3.238931779883691e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Fam163b,0.0029314103737611377,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005379816611527165
+Nebl,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Ift52,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Gria3,0.001967902586694143,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0038154878131655356
+Plcb1,0.00528262065404247,0.0,"[np.float32(0.0), np.float32(0.0)]",0.008856436598309555
+Abhd2,0.0024485565978550434,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00462285509040039
+Chgb,0.003090542676951182,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Cds2,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Ctdspl2,3.351160950598713e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Bdnf,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+D15Ertd621e,0.028789496021219,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04046968223568802
+Rbbp6,0.01804113579317674,0.0,"[np.float32(0.0), np.float32(0.0)]",0.026894041594917695
+Cacng3,0.0003489003923909031,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Ctr9,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Grm5,0.00041725071234339714,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0010112384492156684
+2900076A07Rik,0.0017396855005027702,0.0,"[np.float32(0.0), np.float32(0.0)]",0.003444393197291728
+Mcm8,3.18237465667597e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+H3f3b,0.012793310793119692,0.0,"[np.float32(0.0), np.float32(0.0)]",0.019733128189552303
+Sdk2,0.003090542676951182,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Ap1ar,0.0034586759467470506,0.0,"[np.float32(0.0), np.float32(0.0)]",0.006081938624402004
+Ntng1,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Hipk1,0.028789496021219,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04046968223568802
+Pde4dip,0.0036877347864523514,0.0,"[np.float32(0.0), np.float32(0.0)]",0.006454398302574695
+Trim2,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+B3galnt1,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Nlgn1,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Usp33,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Adcy2,0.011951014216724436,0.0,"[np.float32(0.0), np.float32(0.0)]",0.018618107909651474
+Pitpnc1,0.0020163752208842136,0.0,"[np.float32(0.0), np.float32(0.0)]",0.003901383700387139
+Fam134c,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Appbp2,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Thumpd3,0.0004814080831987388,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0011358316817967722
+Arf5,0.0003758354251119494,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0009228190031292091
+Dync1i1,0.021358472186392776,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03109860035855322
+N4bp2l1,0.02565332721756645,0.0,"[np.float32(0.0), np.float32(0.0)]",0.036695240996992985
+Eln,0.0006183509169962593,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0014108958118292697
+Mphosph9,0.0012891056263238771,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002626086011208947
+Plk2,0.004133681086208618,0.0,"[np.float32(0.0), np.float32(0.0)]",0.007076045116465072
+Ngly1,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Gkap1,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Zmynd11,3.3641788566557923e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Arl15,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
+Dhx29,0.002911299428563695,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005371835533375417
+Hist2h2bb,0.0010552002019996866,0.0,"[np.float32(0.0), np.float32(0.0)]",0.002196084068900349
+Gm16740,0.006848633862201017,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01128248443126482
+S100a13,0.0014359157638968076,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0028795266819409723
+Ilf2,0.012200808738364486,0.0,"[np.float32(0.0), np.float32(0.0)]",0.01891657821265176
+Adar,0.0053614737437652285,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00898058851798097
+Ppm1l,0.009554337900695537,0.0,"[np.float32(0.0), np.float32(0.0)]",0.015175013762479922
+Ppfibp1,0.0038706832121120837,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0067305281504290975
+Egfem1,0.0029314103737611377,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005379816611527165
+Fabp5,0.028789496021219,0.0,"[np.float32(0.0), np.float32(0.0)]",0.04046968223568802
+Pkia,0.007042789317331404,0.0,"[np.float32(0.0), np.float32(0.0)]",0.011528485400461117
+Gnl3,0.009651007649809314,0.0,"[np.float32(0.0), np.float32(0.0)]",0.015289614998131437
+Cyfip2,0.0022115968498836193,0.0,"[np.float32(0.0), np.float32(0.0)]",0.004213745118260948
+Rps27a,0.01028919036576199,0.0,"[np.float32(0.0), np.float32(0.0)]",0.016169741412747622
+Osbp2,0.001402970917602447,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0028195043897252187
+Foxk2,0.022120779734144416,0.0,"[np.float32(0.0), np.float32(0.0)]",0.03205885273631619
+Fam13a,3.33170820268816e-05,0.0,"[np.float32(0.0), np.float32(0.0)]",0.00012613985252110196
+Mrps33,0.00011005040167959152,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0003257979454786641
+Rbm28,0.0003466639676911106,0.0,"[np.float32(0.0), np.float32(0.0)]",0.0008634823203219308
+Fat4,0.0031169344156730086,0.0,"[np.float32(0.0), np.float32(0.0)]",0.005533002174311384
diff --git a/output/tier2_validation/figures/eclip_validation_dentate_gyrus.png b/output/tier2_validation/figures/eclip_validation_dentate_gyrus.png
new file mode 100644
index 0000000000000000000000000000000000000000..a7b68b620509e6c5ca90d67115b8443eafa80e83
Binary files /dev/null and b/output/tier2_validation/figures/eclip_validation_dentate_gyrus.png differ
diff --git a/output/tier2_validation/figures/eclip_validation_pancreas.png b/output/tier2_validation/figures/eclip_validation_pancreas.png
new file mode 100644
index 0000000000000000000000000000000000000000..c08c31afe51803f37a711920fb3cbc14b30d931e
Binary files /dev/null and b/output/tier2_validation/figures/eclip_validation_pancreas.png differ
diff --git a/output/tier2_validation/results/eclip_validation_dentate_gyrus.csv b/output/tier2_validation/results/eclip_validation_dentate_gyrus.csv
new file mode 100644
index 0000000000000000000000000000000000000000..6993b7cee4098f3e613201cbefb3f5369664987a
--- /dev/null
+++ b/output/tier2_validation/results/eclip_validation_dentate_gyrus.csv
@@ -0,0 +1,8 @@
+rbp,n_predicted,n_eclip,n_overlap,odds_ratio,p_value,enrichment_fold
+ELAVL1,14,1267,1,0.24577712966338558,0.9778398726327592,0.30020295410982073
+HNRNPA1,102,74,4,3.0046647230320698,0.05268352827214704,2.821939586645469
+HNRNPC,71,750,10,1.0,0.5524489713820713,1.0
+HNRNPU,1,106,0,0.0,1.0,0.0
+MATR3,54,928,9,0.9471164309031556,0.6151105039723687,0.9563577586206897
+MBNL2,27,196,2,2.104742268041237,0.26183301694731914,2.012471655328798
+RBFOX2,72,949,8,0.5727948990435706,0.9578642752970095,0.6234632946961715
diff --git a/output/tier2_validation/results/eclip_validation_pancreas.csv b/output/tier2_validation/results/eclip_validation_pancreas.csv
new file mode 100644
index 0000000000000000000000000000000000000000..e2394cabaa8f982871d424b2d0dfda1807f7bb5e
--- /dev/null
+++ b/output/tier2_validation/results/eclip_validation_pancreas.csv
@@ -0,0 +1,10 @@
+rbp,n_predicted,n_eclip,n_overlap,odds_ratio,p_value,enrichment_fold
+ELAVL1,73,2326,8,0.5052100617242982,0.983111106207411,0.5609488922131003
+FUS,100,811,12,1.8785413585163273,0.03878646264170394,1.7616769420468557
+HNRNPA1,143,154,3,1.6478713339640492,0.28216973217250924,1.6219235310144402
+HNRNPC,121,1386,23,1.7945558267327475,0.011759249759184623,1.6328455749943354
+HNRNPU,6,221,0,0.0,1.0,0.0
+MATR3,1,1656,1,inf,0.1390895346883924,7.189613526570048
+MBNL2,34,414,1,0.8407806882383153,0.7003098165450776,0.8458368854788292
+RBFOX2,5,2075,1,1.1845467695274832,0.6162202309437845,1.147566265060241
+TRA2B,79,636,3,0.6980543776502869,0.8012740128324319,0.7108908526391211
diff --git a/output/tier2_validation/results/eclip_validation_scifate.csv b/output/tier2_validation/results/eclip_validation_scifate.csv
new file mode 100644
index 0000000000000000000000000000000000000000..214bf1df6e34fddb7c068ab3ae89ad4308c5fb0e
--- /dev/null
+++ b/output/tier2_validation/results/eclip_validation_scifate.csv
@@ -0,0 +1,10 @@
+rbp,n_predicted,n_eclip,n_overlap,odds_ratio,p_value,enrichment_fold
+ELAVL1,62,2274,16,0.8703354257326607,0.7274932579248461,0.9044741396430902
+FUS,94,738,2,0.21089319470699433,0.9989065766174278,0.22977570201233927
+HNRNPA1,103,145,2,1.0695838814650696,0.5627139940456505,1.0672915969199865
+HNRNPC,84,1321,11,0.756415350831329,0.844178202725368,0.7900760607043726
+HNRNPU,91,183,2,0.9557390278726178,0.6225393886529554,0.9571848916111212
+MATR3,84,1551,12,0.6873510937838423,0.9147202463876063,0.734088606429032
+MBNL2,46,358,2,0.9662921348314607,0.6188300792186329,0.9679378188000971
+RBFOX2,89,1809,13,0.579540792404173,0.9794035054625141,0.6435363755504624
+TRA2B,98,626,2,0.2419871794871795,0.9970327517618668,0.25982917128512745
diff --git a/output/tier2_validation/results/sequence_features.json b/output/tier2_validation/results/sequence_features.json
new file mode 100644
index 0000000000000000000000000000000000000000..11a911d349a406995cfbe3a11834088e20a29e16
--- /dev/null
+++ b/output/tier2_validation/results/sequence_features.json
@@ -0,0 +1,35 @@
+{
+ "pancreas": {
+ "utr_length_spearman_r": 0.20794147058538603,
+ "utr_length_p": 7.203218406164233e-85,
+ "au_content_spearman_r": 0.09774073573111283,
+ "au_content_p": 9.267856552130677e-20,
+ "long_vs_short_utr_mw_p": 5.448384030219267e-69,
+ "median_gamma_short_utr": 0.0,
+ "median_gamma_long_utr": 0.24158841371536255,
+ "high_vs_low_au_mw_p": 6.454385542962294e-18,
+ "n_genes": 8624
+ },
+ "dentate_gyrus": {
+ "utr_length_spearman_r": 0.13305228946480288,
+ "utr_length_p": 2.6625450014378587e-17,
+ "au_content_spearman_r": 0.06295684395590402,
+ "au_content_p": 6.62324493719533e-05,
+ "long_vs_short_utr_mw_p": 1.8179303984105497e-15,
+ "median_gamma_short_utr": 0.0,
+ "median_gamma_long_utr": 0.0,
+ "high_vs_low_au_mw_p": 3.407507608419637e-05,
+ "n_genes": 4010
+ },
+ "scifate": {
+ "utr_length_spearman_r": 0.34277289620936613,
+ "utr_length_p": 4.9803739294436434e-203,
+ "au_content_spearman_r": 0.30010938599467263,
+ "au_content_p": 8.10530413924771e-154,
+ "long_vs_short_utr_mw_p": 4.554708034522582e-154,
+ "median_gamma_short_utr": 0.04311377555131912,
+ "median_gamma_long_utr": 0.40713226795196533,
+ "high_vs_low_au_mw_p": 2.0754921973033427e-118,
+ "n_genes": 7398
+ }
+}
\ No newline at end of file
diff --git a/output/tier3/figures/depmap_validation.png b/output/tier3/figures/depmap_validation.png
new file mode 100644
index 0000000000000000000000000000000000000000..3c17c14d8f8b5b74a0216c851970a6816fe915b3
Binary files /dev/null and b/output/tier3/figures/depmap_validation.png differ
diff --git a/output/tier3/results/neuroblastoma_network.csv b/output/tier3/results/neuroblastoma_network.csv
new file mode 100644
index 0000000000000000000000000000000000000000..e48e052dae6251491c1ec68faad8089d7f1a87cf
--- /dev/null
+++ b/output/tier3/results/neuroblastoma_network.csv
@@ -0,0 +1,9113 @@
+rbp,target,spearman_r,direction
+ELAVL1,DOC2B,0.06170518856402139,destabilizing
+ELAVL1,MTMR7,0.09541953599794255,destabilizing
+ELAVL1,FRY,0.08275015784205272,destabilizing
+ELAVL1,MACROD2,0.07515463415587913,destabilizing
+ELAVL1,CENPP,0.13099414391063174,destabilizing
+ELAVL1,KCNB2,0.0874134402166194,destabilizing
+ELAVL1,ALK,0.10845074758060333,destabilizing
+ELAVL1,XKR6,0.08060930270863335,destabilizing
+ELAVL1,MAGI3,0.0685827287499393,destabilizing
+ELAVL1,PTPRS,0.12092009805973968,destabilizing
+ELAVL1,DMD,0.08240132370159149,destabilizing
+ELAVL1,DOCK3,0.07705956509300137,destabilizing
+ELAVL1,FMN2,0.06423230535365858,destabilizing
+ELAVL1,WIPF2,0.07803415383414282,destabilizing
+ELAVL1,DLEU1,0.10978975827787135,destabilizing
+ELAVL1,LRRC37A3,0.07621884482922853,destabilizing
+ELAVL1,EYS,0.056213749722912126,destabilizing
+ELAVL1,MLLT3,0.08743773527820495,destabilizing
+ELAVL1,PTPRD,0.06449470348232847,destabilizing
+ELAVL1,FAM155A,0.11682121035485626,destabilizing
+ELAVL2,TRERF1,0.19995664996172338,destabilizing
+ELAVL2,SORCS1,0.1071637847161866,destabilizing
+ELAVL2,FCHSD2,0.06826001836935125,destabilizing
+ELAVL2,PDE3A,0.19488744725087215,destabilizing
+ELAVL2,UNC79,0.21135198785826453,destabilizing
+ELAVL2,DOC2B,0.13528841433751132,destabilizing
+ELAVL2,TMTC2,0.16184786275503046,destabilizing
+ELAVL2,KALRN,0.13022479079762067,destabilizing
+ELAVL2,CHD1,0.08773575099539563,destabilizing
+ELAVL2,UBE2E2,0.08656477964148,destabilizing
+ELAVL2,PPARD,0.09093301630048649,destabilizing
+ELAVL2,RYR2,0.1799596166496325,destabilizing
+ELAVL2,MTMR7,0.2027694027031937,destabilizing
+ELAVL2,EIF4E,0.13330077851126007,destabilizing
+ELAVL2,SOX11,0.06406793319154658,destabilizing
+ELAVL2,EPB41L4B,0.12756292822726947,destabilizing
+ELAVL2,CACNA1B,0.1172399809400547,destabilizing
+ELAVL2,LRRTM4,0.1275554461402376,destabilizing
+ELAVL2,SIRPA,0.1511374446819523,destabilizing
+ELAVL2,PTEN,0.11258993319489888,destabilizing
+ELAVL2,FRY,0.15666464058572174,destabilizing
+ELAVL2,MACROD2,0.1564062783896739,destabilizing
+ELAVL2,SHANK2,0.21982026964207912,destabilizing
+ELAVL2,CDK12,0.2111345711277809,destabilizing
+ELAVL2,RFX7,0.14310275076656237,destabilizing
+ELAVL2,UBR5,0.08528310767565926,destabilizing
+ELAVL2,JARID2,0.07001222209729568,destabilizing
+ELAVL2,MPHOSPH8,0.11673788667775374,destabilizing
+ELAVL2,DIP2C,0.12628658717579674,destabilizing
+ELAVL2,ZNF423,0.060720421214690866,destabilizing
+ELAVL2,UBR3,0.1256204160506263,destabilizing
+ELAVL2,MGAT5,0.05852734285703205,destabilizing
+ELAVL2,DLG2,0.09878660493706017,destabilizing
+ELAVL2,CHST12,0.21804719146222326,destabilizing
+ELAVL2,EML5,0.17932266478827327,destabilizing
+ELAVL2,CENPP,0.22068353823117828,destabilizing
+ELAVL2,PSME4,0.18198670387148205,destabilizing
+ELAVL2,TMEM106B,0.14189083761761764,destabilizing
+ELAVL2,EPHA5,0.14035833056236083,destabilizing
+ELAVL2,KCNB2,0.18069323539237528,destabilizing
+ELAVL2,ZNF83,0.11010420494470186,destabilizing
+ELAVL2,SOX6,0.09153921517539927,destabilizing
+ELAVL2,ZNF521,0.13571700152041719,destabilizing
+ELAVL2,PLEKHA5,0.09642455531449205,destabilizing
+ELAVL2,NOVA1,0.1631771398472102,destabilizing
+ELAVL2,CCNY,0.17681616959051075,destabilizing
+ELAVL2,ARIH1,0.12261499985200301,destabilizing
+ELAVL2,EPB41L5,0.10394949178540641,destabilizing
+ELAVL2,GPR158,0.15375750736996982,destabilizing
+ELAVL2,NCOA2,0.12298173176830254,destabilizing
+ELAVL2,ALK,0.14868203778144268,destabilizing
+ELAVL2,ARHGAP26,0.06329526761460275,destabilizing
+ELAVL2,CTNND2,0.0563838715851449,destabilizing
+ELAVL2,IFT172,0.15045169363809435,destabilizing
+ELAVL2,CCNT1,0.10786511419436552,destabilizing
+ELAVL2,DTWD2,0.16190179503440044,destabilizing
+ELAVL2,SIK3,0.14199633796298747,destabilizing
+ELAVL2,CPEB3,0.20678336852015186,destabilizing
+ELAVL2,CADM2,0.0808180660324484,destabilizing
+ELAVL2,XKR6,0.19042251466952265,destabilizing
+ELAVL2,CADPS,0.09217992793855667,destabilizing
+ELAVL2,FGF13,0.07529375141918149,destabilizing
+ELAVL2,TCF20,0.15788929924257386,destabilizing
+ELAVL2,CDKAL1,0.07549088544456528,destabilizing
+ELAVL2,DGKI,0.10335378265171499,destabilizing
+ELAVL2,EXOC6B,0.20950855769747448,destabilizing
+ELAVL2,MAGI3,0.1480756797154202,destabilizing
+ELAVL2,SBF2,0.09248071742840797,destabilizing
+ELAVL2,INPP4B,0.15164855882737147,destabilizing
+ELAVL2,PTPRS,0.14128845017386638,destabilizing
+ELAVL2,CBFA2T2,0.08755725186894003,destabilizing
+ELAVL2,SPDYE3,0.1425759585986195,destabilizing
+ELAVL2,TMEM178B,0.06346467028700195,destabilizing
+ELAVL2,DMD,0.2523650911086833,destabilizing
+ELAVL2,MCU,0.14607391760327085,destabilizing
+ELAVL2,SSH2,0.10650353857810747,destabilizing
+ELAVL2,DOCK3,0.18727451254970306,destabilizing
+ELAVL2,HS6ST3,0.1396764183969493,destabilizing
+ELAVL2,LPP,0.17896959934341622,destabilizing
+ELAVL2,STAG1,0.10942016765876829,destabilizing
+ELAVL2,CAPZA2,0.12865163977424507,destabilizing
+ELAVL2,ADGRL3,0.09250880215476018,destabilizing
+ELAVL2,UBE2R2,0.1506768099126112,destabilizing
+ELAVL2,GTF2IRD1,0.13605607231013248,destabilizing
+ELAVL2,CCBE1,0.08375023571677037,destabilizing
+ELAVL2,TTC28,0.11404916011302475,destabilizing
+ELAVL2,SBNO1,0.09796287884260255,destabilizing
+ELAVL2,RIMS2,0.08743293630814088,destabilizing
+ELAVL2,TRIO,0.06529704251811397,destabilizing
+ELAVL2,BTBD9,0.16237729320688346,destabilizing
+ELAVL2,CNGB1,0.18244208101549841,destabilizing
+ELAVL2,FMN2,0.14238249084871088,destabilizing
+ELAVL2,ENSG00000228222,0.19867404934899188,destabilizing
+ELAVL2,PRKN,0.2171680279217905,destabilizing
+ELAVL2,RASA2,0.12492443145296947,destabilizing
+ELAVL2,PPP1R12B,0.09310669709127292,destabilizing
+ELAVL2,FRMD4A,0.11408643144909289,destabilizing
+ELAVL2,CAMK1D,0.06271649086136115,destabilizing
+ELAVL2,SEMA6D,0.1343103699638489,destabilizing
+ELAVL2,WIPF2,0.16048420047029452,destabilizing
+ELAVL2,DLEU1,0.20296606627147143,destabilizing
+ELAVL2,TSHZ2,0.09363692212750602,destabilizing
+ELAVL2,MED13L,0.09225964032483358,destabilizing
+ELAVL2,KAZN,0.14062303169581608,destabilizing
+ELAVL2,KANSL1,0.11494978053183431,destabilizing
+ELAVL2,FRMD5,0.15614105094116656,destabilizing
+ELAVL2,LINC00174,0.12533861877089242,destabilizing
+ELAVL2,PPM1E,0.11998547395452214,destabilizing
+ELAVL2,ARL3,0.07941779617655952,destabilizing
+ELAVL2,MBD5,0.1314251551278435,destabilizing
+ELAVL2,ELAVL3,0.13320374511741825,destabilizing
+ELAVL2,SLIT2,0.17477810675143934,destabilizing
+ELAVL2,CLASP1,0.11849973842175099,destabilizing
+ELAVL2,UNC5C,0.14117260782637658,destabilizing
+ELAVL2,CACNA2D3,-0.05377637939202361,stabilizing
+ELAVL2,RC3H1,0.10905445271652013,destabilizing
+ELAVL2,NEGR1,0.1370902975474068,destabilizing
+ELAVL2,ENOX1,0.18779612477970709,destabilizing
+ELAVL2,SCUBE1,0.08609267918147862,destabilizing
+ELAVL2,GPHN,0.11696996305508427,destabilizing
+ELAVL2,NAV3,0.15508556577271676,destabilizing
+ELAVL2,TOMM22,0.16068929828692763,destabilizing
+ELAVL2,ANKFN1,0.05820602918434517,destabilizing
+ELAVL2,MAGI2,0.07189851016930174,destabilizing
+ELAVL2,LSAMP,0.0582666480172048,destabilizing
+ELAVL2,AKAP6,0.16857392657785772,destabilizing
+ELAVL2,TMED2,0.09060102983850593,destabilizing
+ELAVL2,ZBTB20,0.15233273351643462,destabilizing
+ELAVL2,GRIK2,0.11848887580383309,destabilizing
+ELAVL2,SOX5,0.10050120708136763,destabilizing
+ELAVL2,LRRC37A3,0.1960977165711625,destabilizing
+ELAVL2,TMEM132C,0.052158476283167755,destabilizing
+ELAVL2,EYS,0.12517256334267363,destabilizing
+ELAVL2,ARID1B,0.0894069974350223,destabilizing
+ELAVL2,PRKCE,0.11843687351131231,destabilizing
+ELAVL2,RBFOX1,-0.07727177739201731,stabilizing
+ELAVL2,SDK1,0.09897661669777139,destabilizing
+ELAVL2,NRG1,0.0787115531685712,destabilizing
+ELAVL2,MLLT3,0.1879545636933313,destabilizing
+ELAVL2,FMN1,0.08139100002379013,destabilizing
+ELAVL2,ADGRB3,0.09802317207468589,destabilizing
+ELAVL2,ROBO1,0.14960202732270353,destabilizing
+ELAVL2,SYPL1,0.0570391885384173,destabilizing
+ELAVL2,PTPRD,0.13491081257079557,destabilizing
+ELAVL2,FAM155A,0.13975993115610924,destabilizing
+ELAVL2,LARP1B,0.14911288373543194,destabilizing
+ELAVL3,DGKI,0.06792657446801396,destabilizing
+ELAVL3,DOCK3,0.0855697316048488,destabilizing
+ELAVL3,ELAVL3,-0.2831660638202642,stabilizing
+ELAVL4,TRERF1,0.2752751835389776,destabilizing
+ELAVL4,SORCS1,0.161130198665874,destabilizing
+ELAVL4,NCOA1,0.07094426549526142,destabilizing
+ELAVL4,COPA,0.10732203028393335,destabilizing
+ELAVL4,FCHSD2,0.12812385612010616,destabilizing
+ELAVL4,PDE3A,0.2534872445777657,destabilizing
+ELAVL4,UNC79,0.2681335694231452,destabilizing
+ELAVL4,DOC2B,0.2006185938705801,destabilizing
+ELAVL4,TMTC2,0.24266805756500381,destabilizing
+ELAVL4,KALRN,0.17649063454381916,destabilizing
+ELAVL4,CHD1,0.13721449338915614,destabilizing
+ELAVL4,PAK3,0.07180027772902767,destabilizing
+ELAVL4,UBE2E2,0.10526901012105859,destabilizing
+ELAVL4,PPARD,0.1492202375293546,destabilizing
+ELAVL4,TOX,0.08355753451803952,destabilizing
+ELAVL4,BRAF,0.07407453361426407,destabilizing
+ELAVL4,RYR2,0.2730732597089723,destabilizing
+ELAVL4,MTMR7,0.28141640028277254,destabilizing
+ELAVL4,EIF4E,0.22553474499061255,destabilizing
+ELAVL4,SOX11,0.07695698576400375,destabilizing
+ELAVL4,EPB41L4B,0.1695745587802582,destabilizing
+ELAVL4,CACNA1B,0.16766257245806201,destabilizing
+ELAVL4,TBC1D5,0.08773437554423902,destabilizing
+ELAVL4,LRRTM4,0.17416633125492784,destabilizing
+ELAVL4,SIRPA,0.18875901825201133,destabilizing
+ELAVL4,PTEN,0.16257360555645026,destabilizing
+ELAVL4,FRY,0.2688463090375234,destabilizing
+ELAVL4,MACROD2,0.2266953705697661,destabilizing
+ELAVL4,FOXN3,0.08442238689385796,destabilizing
+ELAVL4,SHANK2,0.31778773962450163,destabilizing
+ELAVL4,CDK12,0.30067442186554405,destabilizing
+ELAVL4,RFX7,0.2196213791736626,destabilizing
+ELAVL4,UBR5,0.12244301129750917,destabilizing
+ELAVL4,JARID2,0.12905953959073932,destabilizing
+ELAVL4,MPHOSPH8,0.17841666747628707,destabilizing
+ELAVL4,DIP2C,0.1645739110805471,destabilizing
+ELAVL4,ZNF423,0.09688280236656512,destabilizing
+ELAVL4,UBR3,0.19262234179574367,destabilizing
+ELAVL4,MGAT5,0.11396631965975325,destabilizing
+ELAVL4,DLG2,0.16786007280097828,destabilizing
+ELAVL4,CHST12,0.3695507711634472,destabilizing
+ELAVL4,EML5,0.2589488161893674,destabilizing
+ELAVL4,CENPP,0.2344978738712039,destabilizing
+ELAVL4,PSME4,0.21850641286792044,destabilizing
+ELAVL4,TMEM106B,0.2814811145790299,destabilizing
+ELAVL4,RABGAP1L,0.06248894797200443,destabilizing
+ELAVL4,EPHA5,0.16807256129706843,destabilizing
+ELAVL4,KCNB2,0.27140174563109604,destabilizing
+ELAVL4,ZNF83,0.15606634288781504,destabilizing
+ELAVL4,SOX6,0.14443423170310393,destabilizing
+ELAVL4,ZNF521,0.24775538003258712,destabilizing
+ELAVL4,PLEKHA5,0.15019110880833667,destabilizing
+ELAVL4,DTL,0.1333696081650369,destabilizing
+ELAVL4,NOVA1,0.28835927334059264,destabilizing
+ELAVL4,CCNY,0.23290932678619938,destabilizing
+ELAVL4,ARIH1,0.1722087789116643,destabilizing
+ELAVL4,FAM171B,0.05149448564535301,destabilizing
+ELAVL4,EPB41L5,0.20079865993029625,destabilizing
+ELAVL4,GPR158,0.23622256180383422,destabilizing
+ELAVL4,NCOA2,0.1839752567671657,destabilizing
+ELAVL4,ALK,0.21128380274255226,destabilizing
+ELAVL4,ACACA,0.10369268511466496,destabilizing
+ELAVL4,ARHGAP26,0.07035364199949193,destabilizing
+ELAVL4,CTNND2,0.10507562016484072,destabilizing
+ELAVL4,IFT172,0.2387811931994486,destabilizing
+ELAVL4,CCNT1,0.14745795251108496,destabilizing
+ELAVL4,DTWD2,0.333771264164,destabilizing
+ELAVL4,SIK3,0.1738952802360539,destabilizing
+ELAVL4,CPEB3,0.23535170268380035,destabilizing
+ELAVL4,CADM2,0.12288888470338807,destabilizing
+ELAVL4,XKR6,0.28019154763661613,destabilizing
+ELAVL4,RMND5A,0.08666161137613011,destabilizing
+ELAVL4,CADPS,0.12548547046156555,destabilizing
+ELAVL4,FGF13,0.08555572699874488,destabilizing
+ELAVL4,TCF20,0.2456233950897215,destabilizing
+ELAVL4,CDKAL1,0.12916780761004443,destabilizing
+ELAVL4,DGKI,0.18816513311035118,destabilizing
+ELAVL4,EXOC6B,0.30909057308565113,destabilizing
+ELAVL4,MAGI3,0.21464655719475007,destabilizing
+ELAVL4,SBF2,0.12450415666855542,destabilizing
+ELAVL4,INPP4B,0.19618399064252276,destabilizing
+ELAVL4,ERC1,0.10325695708771204,destabilizing
+ELAVL4,PTPRS,0.2863456954940076,destabilizing
+ELAVL4,CBFA2T2,0.1238622943322127,destabilizing
+ELAVL4,SPDYE3,0.21971945158305137,destabilizing
+ELAVL4,TMEM178B,0.13402385146337017,destabilizing
+ELAVL4,KMT2C,0.06353166918752759,destabilizing
+ELAVL4,CACNA2D1,0.07094619811609522,destabilizing
+ELAVL4,DMD,0.36725925776844176,destabilizing
+ELAVL4,EIF4G3,0.08309464007472586,destabilizing
+ELAVL4,MCU,0.19995752618873328,destabilizing
+ELAVL4,SSH2,0.1707099844902012,destabilizing
+ELAVL4,TCF12,0.056128414481673126,destabilizing
+ELAVL4,DOCK3,0.24942886208681211,destabilizing
+ELAVL4,HS6ST3,0.23805268734377077,destabilizing
+ELAVL4,LPP,0.25646118677286656,destabilizing
+ELAVL4,STAG1,0.19252653579823747,destabilizing
+ELAVL4,CAPZA2,0.20084147318438322,destabilizing
+ELAVL4,ADGRL3,0.12328291465925677,destabilizing
+ELAVL4,PHACTR1,0.10604919819644873,destabilizing
+ELAVL4,UBE2R2,0.245020522837232,destabilizing
+ELAVL4,GTF2IRD1,0.2030598422996969,destabilizing
+ELAVL4,CCBE1,0.11811950793734435,destabilizing
+ELAVL4,FTX,0.0871181395926112,destabilizing
+ELAVL4,JMJD1C,0.052487000931197514,destabilizing
+ELAVL4,TTC28,0.1268188875887832,destabilizing
+ELAVL4,SBNO1,0.1520872642150029,destabilizing
+ELAVL4,RIMS2,0.1234252714918207,destabilizing
+ELAVL4,IGF1R,0.0958012470984546,destabilizing
+ELAVL4,TRIO,0.10390169146181742,destabilizing
+ELAVL4,KCND2,0.07834812784643169,destabilizing
+ELAVL4,BTBD9,0.21427869157468896,destabilizing
+ELAVL4,CNGB1,0.2928688889927879,destabilizing
+ELAVL4,FMN2,0.18050780612781847,destabilizing
+ELAVL4,ENSG00000228222,0.33610040184422696,destabilizing
+ELAVL4,ATXN1,0.08535651130547069,destabilizing
+ELAVL4,SYN3,0.06005713622698862,destabilizing
+ELAVL4,PRKN,0.26027856127128673,destabilizing
+ELAVL4,RASA2,0.2399342865838883,destabilizing
+ELAVL4,PPP1R12B,0.15594142919558043,destabilizing
+ELAVL4,FRMD4A,0.1902210563880423,destabilizing
+ELAVL4,CAMK1D,0.08842033405602784,destabilizing
+ELAVL4,PARD3,0.06695511186494099,destabilizing
+ELAVL4,SEMA6D,0.19965484905685296,destabilizing
+ELAVL4,WIPF2,0.209745774962594,destabilizing
+ELAVL4,DLEU1,0.28751313684696034,destabilizing
+ELAVL4,TSHZ2,0.1370651824819836,destabilizing
+ELAVL4,MED13L,0.16375261222904944,destabilizing
+ELAVL4,AFF3,0.07704379968218947,destabilizing
+ELAVL4,KAZN,0.2045313695189678,destabilizing
+ELAVL4,KANSL1,0.14519909063434192,destabilizing
+ELAVL4,FRMD5,0.18284877613696887,destabilizing
+ELAVL4,LINC00174,0.21649345770483552,destabilizing
+ELAVL4,PPM1E,0.2038248285557271,destabilizing
+ELAVL4,ARL3,0.14911361380376806,destabilizing
+ELAVL4,MBD5,0.17935527616372274,destabilizing
+ELAVL4,ELAVL3,0.20710912741376922,destabilizing
+ELAVL4,SLIT2,0.2842926705850459,destabilizing
+ELAVL4,SLC8A1,0.06867891168140931,destabilizing
+ELAVL4,CLASP1,0.1488283910744024,destabilizing
+ELAVL4,DOCK4,0.051946092051911426,destabilizing
+ELAVL4,UNC5C,0.20042125927296245,destabilizing
+ELAVL4,CACNA2D3,-0.10820847650955501,stabilizing
+ELAVL4,RC3H1,0.16476242394954976,destabilizing
+ELAVL4,NEGR1,0.22985323644569186,destabilizing
+ELAVL4,ENOX1,0.30217266670516013,destabilizing
+ELAVL4,SCUBE1,0.13946162347708765,destabilizing
+ELAVL4,GPHN,0.17070204233206,destabilizing
+ELAVL4,NAV3,0.24853300337343767,destabilizing
+ELAVL4,EBF1,0.10250177167468241,destabilizing
+ELAVL4,TOMM22,0.23337428531804916,destabilizing
+ELAVL4,MBNL2,0.10027930281443055,destabilizing
+ELAVL4,ANKFN1,0.07273237257490613,destabilizing
+ELAVL4,MAGI2,0.10902263985712789,destabilizing
+ELAVL4,LSAMP,0.13498006309706292,destabilizing
+ELAVL4,AKAP6,0.2191096523179601,destabilizing
+ELAVL4,TMED2,0.15205489560617272,destabilizing
+ELAVL4,ZBTB20,0.20262821738049222,destabilizing
+ELAVL4,GRIK2,0.20991103073695416,destabilizing
+ELAVL4,SOX5,0.15505280792497877,destabilizing
+ELAVL4,LRRC37A3,0.28479009331859423,destabilizing
+ELAVL4,TMEM132C,0.07809699110745427,destabilizing
+ELAVL4,EYS,0.18138349423169844,destabilizing
+ELAVL4,ARID1B,0.16498938913733244,destabilizing
+ELAVL4,PRKCE,0.15480684845512196,destabilizing
+ELAVL4,RBFOX1,-0.1117585124163893,stabilizing
+ELAVL4,SDK1,0.11896286522494412,destabilizing
+ELAVL4,NRG1,0.08871252490846951,destabilizing
+ELAVL4,MLLT3,0.3012932292493041,destabilizing
+ELAVL4,FMN1,0.13886300487649364,destabilizing
+ELAVL4,ADGRB3,0.1396145964977271,destabilizing
+ELAVL4,ROBO1,0.21642001315292658,destabilizing
+ELAVL4,SYPL1,0.117964511522904,destabilizing
+ELAVL4,PTPRD,0.19723517454277098,destabilizing
+ELAVL4,FAM155A,0.1925094633112759,destabilizing
+ELAVL4,LARP1B,0.21207158109981475,destabilizing
+HNRNPA2B1,TRERF1,0.2610031489047995,destabilizing
+HNRNPA2B1,SORCS1,0.13738968755005407,destabilizing
+HNRNPA2B1,COPA,0.08710899398455185,destabilizing
+HNRNPA2B1,FCHSD2,0.11688686577430424,destabilizing
+HNRNPA2B1,PDE3A,0.15715430138991948,destabilizing
+HNRNPA2B1,UNC79,0.27059328753129636,destabilizing
+HNRNPA2B1,DOC2B,0.17883993147665944,destabilizing
+HNRNPA2B1,TMTC2,0.2690870707561141,destabilizing
+HNRNPA2B1,KALRN,0.1602096103192483,destabilizing
+HNRNPA2B1,CHD1,0.10247493352902172,destabilizing
+HNRNPA2B1,PAK3,0.06745416856760363,destabilizing
+HNRNPA2B1,UBE2E2,0.0904953616612898,destabilizing
+HNRNPA2B1,PPARD,0.12177600617657018,destabilizing
+HNRNPA2B1,TOX,0.10615821383965869,destabilizing
+HNRNPA2B1,BRAF,0.11356125817274905,destabilizing
+HNRNPA2B1,RYR2,0.24739218977800773,destabilizing
+HNRNPA2B1,MTMR7,0.27900400609209886,destabilizing
+HNRNPA2B1,EIF4E,0.2842430463600914,destabilizing
+HNRNPA2B1,SOX11,0.07747494788732077,destabilizing
+HNRNPA2B1,EPB41L4B,0.10983644542376376,destabilizing
+HNRNPA2B1,CACNA1B,0.16353203204532493,destabilizing
+HNRNPA2B1,TBC1D5,0.07554413725318394,destabilizing
+HNRNPA2B1,WSB1,0.0770588692472026,destabilizing
+HNRNPA2B1,LRRTM4,0.11875000728057106,destabilizing
+HNRNPA2B1,SIRPA,0.11550650222973459,destabilizing
+HNRNPA2B1,PTEN,0.14180672742467373,destabilizing
+HNRNPA2B1,SPPL3,0.07594545986713785,destabilizing
+HNRNPA2B1,FRY,0.29993536605870363,destabilizing
+HNRNPA2B1,RUNX1T1,0.11431854882787412,destabilizing
+HNRNPA2B1,MACROD2,0.25121266409583143,destabilizing
+HNRNPA2B1,SHANK2,0.2821621433047515,destabilizing
+HNRNPA2B1,CDK12,0.3959933651625223,destabilizing
+HNRNPA2B1,BMPR1B,0.052413293351886985,destabilizing
+HNRNPA2B1,RFX7,0.22180876896504065,destabilizing
+HNRNPA2B1,UBR5,0.06190913246204633,destabilizing
+HNRNPA2B1,JARID2,0.10637803507460011,destabilizing
+HNRNPA2B1,MPHOSPH8,0.2579484131006539,destabilizing
+HNRNPA2B1,DIP2C,0.14623672311215524,destabilizing
+HNRNPA2B1,ZNF423,0.09432970746276322,destabilizing
+HNRNPA2B1,UBR3,0.13243603376633492,destabilizing
+HNRNPA2B1,DLG2,0.17341517144134275,destabilizing
+HNRNPA2B1,CHST12,0.3748323142750196,destabilizing
+HNRNPA2B1,EML5,0.23433406231370055,destabilizing
+HNRNPA2B1,CENPP,0.49183205676936975,destabilizing
+HNRNPA2B1,PSME4,0.17183243960352002,destabilizing
+HNRNPA2B1,TMEM106B,0.21859804795387625,destabilizing
+HNRNPA2B1,RABGAP1L,0.07066430190783642,destabilizing
+HNRNPA2B1,EPHA5,0.1829180954942237,destabilizing
+HNRNPA2B1,KCNB2,0.35716475843119677,destabilizing
+HNRNPA2B1,ZNF83,0.18285500795760265,destabilizing
+HNRNPA2B1,SOX6,0.20388817243130875,destabilizing
+HNRNPA2B1,ZNF521,0.2216256435433421,destabilizing
+HNRNPA2B1,PLEKHA5,0.13505269830970862,destabilizing
+HNRNPA2B1,DTL,-0.1769211744631474,stabilizing
+HNRNPA2B1,NOVA1,0.3026964845590675,destabilizing
+HNRNPA2B1,CCNY,0.23554933122985994,destabilizing
+HNRNPA2B1,ARIH1,0.14569593557642022,destabilizing
+HNRNPA2B1,FAM171B,0.05635021887895639,destabilizing
+HNRNPA2B1,EPB41L5,0.1181230127573864,destabilizing
+HNRNPA2B1,GPR158,0.2142683744023116,destabilizing
+HNRNPA2B1,NCOA2,0.11872133166255683,destabilizing
+HNRNPA2B1,MARCKS,0.083420929457227,destabilizing
+HNRNPA2B1,ALK,0.4486625702957564,destabilizing
+HNRNPA2B1,ACACA,0.06677559568758186,destabilizing
+HNRNPA2B1,ARHGAP26,0.0572101919220396,destabilizing
+HNRNPA2B1,CTNND2,0.07150590553188617,destabilizing
+HNRNPA2B1,IFT172,0.25622649783591395,destabilizing
+HNRNPA2B1,CCNT1,0.14608950539660778,destabilizing
+HNRNPA2B1,DTWD2,0.39038084787694327,destabilizing
+HNRNPA2B1,SIK3,0.16248127356083178,destabilizing
+HNRNPA2B1,CPEB3,0.26053219707468944,destabilizing
+HNRNPA2B1,CADM2,0.13780255283490828,destabilizing
+HNRNPA2B1,XKR6,0.26177667817562544,destabilizing
+HNRNPA2B1,RMND5A,0.08375615672638996,destabilizing
+HNRNPA2B1,CADPS,0.14218665574067066,destabilizing
+HNRNPA2B1,FGF13,0.12081016805771538,destabilizing
+HNRNPA2B1,TCF20,0.16588420691380176,destabilizing
+HNRNPA2B1,CDKAL1,0.1648396233273334,destabilizing
+HNRNPA2B1,DGKI,0.19646082725009614,destabilizing
+HNRNPA2B1,EXOC6B,0.24913973660293287,destabilizing
+HNRNPA2B1,MAGI3,0.2611121890287891,destabilizing
+HNRNPA2B1,SBF2,0.1229851787040934,destabilizing
+HNRNPA2B1,INPP4B,0.1645065873180578,destabilizing
+HNRNPA2B1,PTPRS,0.24155031082294504,destabilizing
+HNRNPA2B1,CBFA2T2,0.09377807262580072,destabilizing
+HNRNPA2B1,SPDYE3,0.11678673095604458,destabilizing
+HNRNPA2B1,TMEM178B,0.11979920103370674,destabilizing
+HNRNPA2B1,DMD,0.32589481893176814,destabilizing
+HNRNPA2B1,EIF4G3,0.08683348227408878,destabilizing
+HNRNPA2B1,MCU,0.16743325735509293,destabilizing
+HNRNPA2B1,SSH2,0.18872306626825722,destabilizing
+HNRNPA2B1,DOCK3,0.2864017692583704,destabilizing
+HNRNPA2B1,HS6ST3,0.13824911200777967,destabilizing
+HNRNPA2B1,LPP,0.16946154235851377,destabilizing
+HNRNPA2B1,STAG1,0.15807223751200078,destabilizing
+HNRNPA2B1,CAPZA2,0.2493283648075011,destabilizing
+HNRNPA2B1,ADGRL3,0.1251225284577793,destabilizing
+HNRNPA2B1,PHACTR1,0.16115373603416838,destabilizing
+HNRNPA2B1,UBE2R2,0.23255860208615414,destabilizing
+HNRNPA2B1,GTF2IRD1,0.14646896973369217,destabilizing
+HNRNPA2B1,CCBE1,0.0541598075944536,destabilizing
+HNRNPA2B1,FTX,0.08237302892212409,destabilizing
+HNRNPA2B1,VAPA,0.08796949770150843,destabilizing
+HNRNPA2B1,JMJD1C,0.08334114929096585,destabilizing
+HNRNPA2B1,TTC28,0.20273076197551765,destabilizing
+HNRNPA2B1,SBNO1,0.09854495669941037,destabilizing
+HNRNPA2B1,RIMS2,0.17090050994475103,destabilizing
+HNRNPA2B1,IGF1R,0.05986556916380853,destabilizing
+HNRNPA2B1,KCND2,0.0628877923143634,destabilizing
+HNRNPA2B1,BTBD9,0.18278798869354024,destabilizing
+HNRNPA2B1,CNGB1,0.23521470202227573,destabilizing
+HNRNPA2B1,FMN2,0.16123771569895506,destabilizing
+HNRNPA2B1,ENSG00000228222,0.35666731108995503,destabilizing
+HNRNPA2B1,ATXN1,0.09351375252450056,destabilizing
+HNRNPA2B1,SYN3,0.1100631541570487,destabilizing
+HNRNPA2B1,PRKN,0.1957465657743073,destabilizing
+HNRNPA2B1,RASA2,0.27730051913744724,destabilizing
+HNRNPA2B1,PPP1R12B,0.1514822700758653,destabilizing
+HNRNPA2B1,FRMD4A,0.15375448698130176,destabilizing
+HNRNPA2B1,PARD3,0.06007647395591043,destabilizing
+HNRNPA2B1,SEMA6D,0.2137360173359014,destabilizing
+HNRNPA2B1,WIPF2,0.2678051662757599,destabilizing
+HNRNPA2B1,DLEU1,0.24033996341876182,destabilizing
+HNRNPA2B1,TSHZ2,0.15059495609790594,destabilizing
+HNRNPA2B1,MED13L,0.10275269873158852,destabilizing
+HNRNPA2B1,AFF3,0.07910498263027706,destabilizing
+HNRNPA2B1,KAZN,0.14232249353701965,destabilizing
+HNRNPA2B1,KANSL1,0.13718622261555735,destabilizing
+HNRNPA2B1,FRMD5,0.16690137740587685,destabilizing
+HNRNPA2B1,LINC00174,0.2580732221889417,destabilizing
+HNRNPA2B1,PPM1E,0.12324535437854128,destabilizing
+HNRNPA2B1,ARL3,0.20654593456120152,destabilizing
+HNRNPA2B1,MBD5,0.18480742373601378,destabilizing
+HNRNPA2B1,ELAVL3,0.2218416062232805,destabilizing
+HNRNPA2B1,SLIT2,0.2323888192451743,destabilizing
+HNRNPA2B1,CLASP1,0.16716909376240824,destabilizing
+HNRNPA2B1,UNC5C,0.20941900231323088,destabilizing
+HNRNPA2B1,CACNA2D3,-0.07433399322209389,stabilizing
+HNRNPA2B1,RC3H1,0.11498280020701937,destabilizing
+HNRNPA2B1,NEGR1,0.2653782071019182,destabilizing
+HNRNPA2B1,ENOX1,0.31943165964636244,destabilizing
+HNRNPA2B1,SCUBE1,0.09849179580505825,destabilizing
+HNRNPA2B1,GPHN,0.13131620242385023,destabilizing
+HNRNPA2B1,NAV3,0.1900968977003605,destabilizing
+HNRNPA2B1,EBF1,0.09828329159745931,destabilizing
+HNRNPA2B1,TOMM22,0.27501027675217976,destabilizing
+HNRNPA2B1,MBNL2,0.06663660978167979,destabilizing
+HNRNPA2B1,ANKFN1,0.12886200614199417,destabilizing
+HNRNPA2B1,MAGI2,0.07916946335766871,destabilizing
+HNRNPA2B1,LSAMP,0.1440570055243169,destabilizing
+HNRNPA2B1,AKAP6,0.19086972702851146,destabilizing
+HNRNPA2B1,TMED2,0.16881462462912106,destabilizing
+HNRNPA2B1,ZBTB20,0.21253595307518777,destabilizing
+HNRNPA2B1,GRIK2,0.1843141248063325,destabilizing
+HNRNPA2B1,MAML3,0.06317534065067265,destabilizing
+HNRNPA2B1,SOX5,0.13909471982547658,destabilizing
+HNRNPA2B1,LRRC37A3,0.32938076798906046,destabilizing
+HNRNPA2B1,TMEM132C,0.08812308511180118,destabilizing
+HNRNPA2B1,EYS,0.15929803484640254,destabilizing
+HNRNPA2B1,ARID1B,0.11796369187179555,destabilizing
+HNRNPA2B1,PRKCE,0.11722964000861597,destabilizing
+HNRNPA2B1,RBFOX1,-0.11997910749953976,stabilizing
+HNRNPA2B1,SDK1,0.10390747475001243,destabilizing
+HNRNPA2B1,NRG1,0.10293736396598212,destabilizing
+HNRNPA2B1,RORA,0.10255004057747803,destabilizing
+HNRNPA2B1,MLLT3,0.37208253035881145,destabilizing
+HNRNPA2B1,FMN1,0.08935168216464462,destabilizing
+HNRNPA2B1,ADGRB3,0.10750054510577844,destabilizing
+HNRNPA2B1,ROBO1,0.12591752462662417,destabilizing
+HNRNPA2B1,SYPL1,0.17095727297350713,destabilizing
+HNRNPA2B1,PTPRD,0.20648123560041193,destabilizing
+HNRNPA2B1,FAM155A,0.23583910019460153,destabilizing
+HNRNPA2B1,LARP1B,0.17577355644246162,destabilizing
+HNRNPC,TRERF1,0.231060398109268,destabilizing
+HNRNPC,SORCS1,0.11298729730826211,destabilizing
+HNRNPC,NCOA1,0.0786026270195814,destabilizing
+HNRNPC,COPA,0.09763663447020482,destabilizing
+HNRNPC,FCHSD2,0.10522132289126476,destabilizing
+HNRNPC,PDE3A,0.2125265048199512,destabilizing
+HNRNPC,UNC79,0.2353038321989986,destabilizing
+HNRNPC,DOC2B,0.1639483067467411,destabilizing
+HNRNPC,TMTC2,0.222448906315073,destabilizing
+HNRNPC,KALRN,0.1324255801309177,destabilizing
+HNRNPC,CHD1,0.11268822789617433,destabilizing
+HNRNPC,PAK3,0.05539975578117921,destabilizing
+HNRNPC,UBE2E2,0.060277537200109525,destabilizing
+HNRNPC,PPARD,0.11714594452417207,destabilizing
+HNRNPC,TOX,0.10355901461501267,destabilizing
+HNRNPC,BRAF,0.08596668189071004,destabilizing
+HNRNPC,RYR2,0.1811083826050357,destabilizing
+HNRNPC,MTMR7,0.257767590734214,destabilizing
+HNRNPC,EIF4E,0.23330189562676928,destabilizing
+HNRNPC,SOX11,0.08418868482404689,destabilizing
+HNRNPC,EPB41L4B,0.11677766633631571,destabilizing
+HNRNPC,CACNA1B,0.16024821698980202,destabilizing
+HNRNPC,TBC1D5,0.06595928560789682,destabilizing
+HNRNPC,LRRTM4,0.14166227613169935,destabilizing
+HNRNPC,SIRPA,0.150131983501036,destabilizing
+HNRNPC,PTEN,0.13211116722808958,destabilizing
+HNRNPC,FRY,0.24383759472879638,destabilizing
+HNRNPC,RUNX1T1,0.08478469369589214,destabilizing
+HNRNPC,MACROD2,0.2117867195374158,destabilizing
+HNRNPC,SHANK2,0.24925995224706385,destabilizing
+HNRNPC,CDK12,0.2882165767715756,destabilizing
+HNRNPC,RFX7,0.2246633038055398,destabilizing
+HNRNPC,UBR5,0.07643522897521521,destabilizing
+HNRNPC,JARID2,0.09653504054412107,destabilizing
+HNRNPC,MPHOSPH8,0.20421808347708045,destabilizing
+HNRNPC,DIP2C,0.1269695901891174,destabilizing
+HNRNPC,ZNF423,0.07483723457396169,destabilizing
+HNRNPC,UBR3,0.12428948215220469,destabilizing
+HNRNPC,MGAT5,0.06307355579017639,destabilizing
+HNRNPC,DLG2,0.1369152207380881,destabilizing
+HNRNPC,CHST12,0.3193528261848278,destabilizing
+HNRNPC,EML5,0.22011180308044107,destabilizing
+HNRNPC,CENPP,0.3132990934812013,destabilizing
+HNRNPC,PSME4,0.17379799185279324,destabilizing
+HNRNPC,TMEM106B,0.1923096244319849,destabilizing
+HNRNPC,EPHA5,0.1600733941162831,destabilizing
+HNRNPC,KCNB2,0.23976541478833205,destabilizing
+HNRNPC,ZNF83,0.14142778881730275,destabilizing
+HNRNPC,SOX6,0.1503449223946514,destabilizing
+HNRNPC,ZNF521,0.1826212930423379,destabilizing
+HNRNPC,PLEKHA5,0.1390551175092279,destabilizing
+HNRNPC,NOVA1,0.24164424972225035,destabilizing
+HNRNPC,CCNY,0.20616935283216276,destabilizing
+HNRNPC,ARIH1,0.12876841632481287,destabilizing
+HNRNPC,FAM171B,0.06346846580134356,destabilizing
+HNRNPC,EPB41L5,0.13787802380122893,destabilizing
+HNRNPC,GPR158,0.19496017061792228,destabilizing
+HNRNPC,NCOA2,0.118948445197823,destabilizing
+HNRNPC,MARCKS,0.07242839833153404,destabilizing
+HNRNPC,ALK,0.24214423719124664,destabilizing
+HNRNPC,ACACA,0.0962680762998523,destabilizing
+HNRNPC,CTNND2,0.09059230508397008,destabilizing
+HNRNPC,IFT172,0.20178349259962086,destabilizing
+HNRNPC,CCNT1,0.12600208946960695,destabilizing
+HNRNPC,DTWD2,0.3229522248362295,destabilizing
+HNRNPC,SIK3,0.1107507178968132,destabilizing
+HNRNPC,CPEB3,0.24547570279231842,destabilizing
+HNRNPC,CADM2,0.10174412625960476,destabilizing
+HNRNPC,XKR6,0.2190170545638579,destabilizing
+HNRNPC,RMND5A,0.07901408806611272,destabilizing
+HNRNPC,CADPS,0.11863089308977896,destabilizing
+HNRNPC,FGF13,0.08840118429014027,destabilizing
+HNRNPC,TCF20,0.18788269349051878,destabilizing
+HNRNPC,CDKAL1,0.11125736592696774,destabilizing
+HNRNPC,DGKI,0.14718952454002743,destabilizing
+HNRNPC,EXOC6B,0.23249918629808167,destabilizing
+HNRNPC,MAGI3,0.20919569317337025,destabilizing
+HNRNPC,SBF2,0.10690541313709855,destabilizing
+HNRNPC,INPP4B,0.1620490466288748,destabilizing
+HNRNPC,ERC1,0.07161995740031402,destabilizing
+HNRNPC,PTPRS,0.19909193605176154,destabilizing
+HNRNPC,CBFA2T2,0.08869175714321405,destabilizing
+HNRNPC,SPDYE3,0.12978298080917536,destabilizing
+HNRNPC,TMEM178B,0.09766975480570077,destabilizing
+HNRNPC,DMD,0.2803405326559565,destabilizing
+HNRNPC,EIF4G3,0.08832020913117727,destabilizing
+HNRNPC,MCU,0.13605356863488502,destabilizing
+HNRNPC,SSH2,0.15378521752408086,destabilizing
+HNRNPC,DOCK3,0.2307671513798443,destabilizing
+HNRNPC,HS6ST3,0.1772175929421168,destabilizing
+HNRNPC,LPP,0.1668013370762488,destabilizing
+HNRNPC,STAG1,0.13471684624203048,destabilizing
+HNRNPC,CAPZA2,0.19296655288281558,destabilizing
+HNRNPC,ADGRL3,0.1031360772632482,destabilizing
+HNRNPC,PHACTR1,0.10413432301465649,destabilizing
+HNRNPC,UBE2R2,0.18147870367494856,destabilizing
+HNRNPC,GTF2IRD1,0.14869290859815665,destabilizing
+HNRNPC,CCBE1,0.07841603195689306,destabilizing
+HNRNPC,FTX,0.08039272118185228,destabilizing
+HNRNPC,VAPA,0.07525004599932969,destabilizing
+HNRNPC,JMJD1C,0.0635375830056763,destabilizing
+HNRNPC,TTC28,0.14145730606413626,destabilizing
+HNRNPC,SBNO1,0.11222609373815734,destabilizing
+HNRNPC,RIMS2,0.14352784778883254,destabilizing
+HNRNPC,IGF1R,0.058826569690383426,destabilizing
+HNRNPC,TRIO,0.060964415537254235,destabilizing
+HNRNPC,KCND2,0.0795222070745369,destabilizing
+HNRNPC,BTBD9,0.1845236907939737,destabilizing
+HNRNPC,CNGB1,0.19879493780862342,destabilizing
+HNRNPC,FMN2,0.1596331369991081,destabilizing
+HNRNPC,ENSG00000228222,0.3060355064675134,destabilizing
+HNRNPC,ATXN1,0.06494011091200377,destabilizing
+HNRNPC,SYN3,0.05659001912212223,destabilizing
+HNRNPC,PRKN,0.2172186713074405,destabilizing
+HNRNPC,RASA2,0.24137567516524847,destabilizing
+HNRNPC,PPP1R12B,0.15289076489119366,destabilizing
+HNRNPC,FRMD4A,0.14084930207956206,destabilizing
+HNRNPC,SEMA6D,0.1800397921611351,destabilizing
+HNRNPC,WIPF2,0.2067014775503558,destabilizing
+HNRNPC,DLEU1,0.25076466527610386,destabilizing
+HNRNPC,TSHZ2,0.11584441348569009,destabilizing
+HNRNPC,MED13L,0.13742267165638913,destabilizing
+HNRNPC,AFF3,0.06209284484340786,destabilizing
+HNRNPC,KAZN,0.16005055414271802,destabilizing
+HNRNPC,KANSL1,0.12452404892707815,destabilizing
+HNRNPC,FRMD5,0.13871033076192602,destabilizing
+HNRNPC,LINC00174,0.19793683558096925,destabilizing
+HNRNPC,PPM1E,0.15043221331859855,destabilizing
+HNRNPC,ARL3,0.15544616180706436,destabilizing
+HNRNPC,MBD5,0.15462158864087588,destabilizing
+HNRNPC,ELAVL3,0.16640645729402165,destabilizing
+HNRNPC,SLIT2,0.20916489241000397,destabilizing
+HNRNPC,SLC8A1,0.06635032906598218,destabilizing
+HNRNPC,CLASP1,0.11891610844911842,destabilizing
+HNRNPC,DOCK4,0.05142896379272997,destabilizing
+HNRNPC,UNC5C,0.18606874227965622,destabilizing
+HNRNPC,CACNA2D3,-0.05735003396268509,stabilizing
+HNRNPC,RC3H1,0.10422540485770054,destabilizing
+HNRNPC,NEGR1,0.19722175230708136,destabilizing
+HNRNPC,ENOX1,0.2810534863198196,destabilizing
+HNRNPC,SCUBE1,0.11099250142496032,destabilizing
+HNRNPC,GPHN,0.1300766287967573,destabilizing
+HNRNPC,NAV3,0.1855628830142362,destabilizing
+HNRNPC,EBF1,0.08055489417424949,destabilizing
+HNRNPC,TOMM22,0.22613959257198837,destabilizing
+HNRNPC,MBNL2,0.07453723155951068,destabilizing
+HNRNPC,ANKFN1,0.07943711664316398,destabilizing
+HNRNPC,MAGI2,0.07510963123002581,destabilizing
+HNRNPC,LSAMP,0.13514065941615636,destabilizing
+HNRNPC,AKAP6,0.17629290131172365,destabilizing
+HNRNPC,TMED2,0.1599302855656624,destabilizing
+HNRNPC,ZBTB20,0.17675032451377246,destabilizing
+HNRNPC,GRIK2,0.1681470479827067,destabilizing
+HNRNPC,SOX5,0.12101183315191223,destabilizing
+HNRNPC,LRRC37A3,0.2655676515007118,destabilizing
+HNRNPC,TMEM132C,0.07748621125102,destabilizing
+HNRNPC,EYS,0.1338522409458726,destabilizing
+HNRNPC,ARID1B,0.12883408900252744,destabilizing
+HNRNPC,PRKCE,0.12448472921512982,destabilizing
+HNRNPC,RBFOX1,-0.08012276208286355,stabilizing
+HNRNPC,SDK1,0.09690918359327597,destabilizing
+HNRNPC,NRG1,0.08341302442087162,destabilizing
+HNRNPC,MLLT3,0.28792742859843906,destabilizing
+HNRNPC,FMN1,0.07211426502009409,destabilizing
+HNRNPC,ADGRB3,0.11087107733777096,destabilizing
+HNRNPC,ROBO1,0.14451125310075402,destabilizing
+HNRNPC,SYPL1,0.12604681917059202,destabilizing
+HNRNPC,PTPRD,0.1564005987655075,destabilizing
+HNRNPC,FAM155A,0.1885427709049661,destabilizing
+HNRNPC,LARP1B,0.1808745887915809,destabilizing
+HNRNPD,TRERF1,0.1806701037614353,destabilizing
+HNRNPD,SORCS1,0.09105972109414646,destabilizing
+HNRNPD,FCHSD2,0.075174993222673,destabilizing
+HNRNPD,PDE3A,0.1403092219599431,destabilizing
+HNRNPD,UNC79,0.15908748699800782,destabilizing
+HNRNPD,DOC2B,0.1211022303590425,destabilizing
+HNRNPD,TMTC2,0.1708402761423718,destabilizing
+HNRNPD,KALRN,0.10967437179508194,destabilizing
+HNRNPD,CHD1,0.08324112390202999,destabilizing
+HNRNPD,UBE2E2,0.07234841922794864,destabilizing
+HNRNPD,PPARD,0.10429986730000596,destabilizing
+HNRNPD,TOX,0.09544612348074377,destabilizing
+HNRNPD,BRAF,0.07167244406240823,destabilizing
+HNRNPD,RYR2,0.2103955509347638,destabilizing
+HNRNPD,MTMR7,0.18971691643433186,destabilizing
+HNRNPD,EIF4E,0.24752042828965698,destabilizing
+HNRNPD,SOX11,0.06369304726098671,destabilizing
+HNRNPD,EPB41L4B,0.07484508503274304,destabilizing
+HNRNPD,CACNA1B,0.10888106791813244,destabilizing
+HNRNPD,LRRTM4,0.07964636132004764,destabilizing
+HNRNPD,PTEN,0.09655412146195576,destabilizing
+HNRNPD,FRY,0.21262443969474595,destabilizing
+HNRNPD,RUNX1T1,0.06790104873480507,destabilizing
+HNRNPD,MACROD2,0.171489572348535,destabilizing
+HNRNPD,SHANK2,0.15953479236810858,destabilizing
+HNRNPD,CDK12,0.23269032114067767,destabilizing
+HNRNPD,RFX7,0.16386942837378474,destabilizing
+HNRNPD,UBR5,0.06952968857859862,destabilizing
+HNRNPD,JARID2,0.09059693834433219,destabilizing
+HNRNPD,MPHOSPH8,0.16572413277986384,destabilizing
+HNRNPD,DIP2C,0.1216491938767006,destabilizing
+HNRNPD,ZNF423,0.06185009363793958,destabilizing
+HNRNPD,UBR3,0.10018094618982334,destabilizing
+HNRNPD,DLG2,0.11166354398656697,destabilizing
+HNRNPD,CHST12,0.25506420921086165,destabilizing
+HNRNPD,EML5,0.1750638506720888,destabilizing
+HNRNPD,CENPP,0.35157860994390744,destabilizing
+HNRNPD,PSME4,0.13576007661458087,destabilizing
+HNRNPD,TMEM106B,0.1395468412477547,destabilizing
+HNRNPD,EPHA5,0.10622101489063028,destabilizing
+HNRNPD,KCNB2,0.25148013410808717,destabilizing
+HNRNPD,ZNF83,0.1440030348095484,destabilizing
+HNRNPD,SOX6,0.13575187263895608,destabilizing
+HNRNPD,ZNF521,0.14906554947362327,destabilizing
+HNRNPD,PLEKHA5,0.09217498762284349,destabilizing
+HNRNPD,NOVA1,0.1931032470109805,destabilizing
+HNRNPD,CCNY,0.15201716030931495,destabilizing
+HNRNPD,ARIH1,0.12199056528840364,destabilizing
+HNRNPD,EPB41L5,0.10861576831342047,destabilizing
+HNRNPD,GPR158,0.14345060525172956,destabilizing
+HNRNPD,NCOA2,0.07717126937063588,destabilizing
+HNRNPD,ALK,0.30031504093267664,destabilizing
+HNRNPD,IFT172,0.14481625148487295,destabilizing
+HNRNPD,CCNT1,0.10114512848193634,destabilizing
+HNRNPD,DTWD2,0.25129559142040264,destabilizing
+HNRNPD,SIK3,0.1312179778656311,destabilizing
+HNRNPD,CPEB3,0.18308110301954997,destabilizing
+HNRNPD,CADM2,0.07218384149602439,destabilizing
+HNRNPD,XKR6,0.1814988593122154,destabilizing
+HNRNPD,CADPS,0.10530950379559877,destabilizing
+HNRNPD,FGF13,0.06970176749211839,destabilizing
+HNRNPD,TCF20,0.12306630704782562,destabilizing
+HNRNPD,CDKAL1,0.11338147913948977,destabilizing
+HNRNPD,DGKI,0.1382327104389376,destabilizing
+HNRNPD,EXOC6B,0.18143511868774617,destabilizing
+HNRNPD,MAGI3,0.1651629186133529,destabilizing
+HNRNPD,SBF2,0.09970657804187448,destabilizing
+HNRNPD,INPP4B,0.0933056048041366,destabilizing
+HNRNPD,PTPRS,0.15424933924989953,destabilizing
+HNRNPD,CBFA2T2,0.057977426827542526,destabilizing
+HNRNPD,SPDYE3,0.08569501789808105,destabilizing
+HNRNPD,TMEM178B,0.0697517527583941,destabilizing
+HNRNPD,DMD,0.23223170876648616,destabilizing
+HNRNPD,EIF4G3,0.06380662512311666,destabilizing
+HNRNPD,MCU,0.1550186212697415,destabilizing
+HNRNPD,SSH2,0.12624132480055955,destabilizing
+HNRNPD,DOCK3,0.19290778138433073,destabilizing
+HNRNPD,HS6ST3,0.0927100467409405,destabilizing
+HNRNPD,LPP,0.13337988183671298,destabilizing
+HNRNPD,STAG1,0.12960670945169087,destabilizing
+HNRNPD,CAPZA2,0.16659368345660963,destabilizing
+HNRNPD,ADGRL3,0.0769215545915595,destabilizing
+HNRNPD,PHACTR1,0.09646517678542471,destabilizing
+HNRNPD,UBE2R2,0.1362232559470319,destabilizing
+HNRNPD,GTF2IRD1,0.10085021933104928,destabilizing
+HNRNPD,TTC28,0.12800508886405082,destabilizing
+HNRNPD,SBNO1,0.07221001354004838,destabilizing
+HNRNPD,RIMS2,0.10939615008510654,destabilizing
+HNRNPD,BTBD9,0.11084247261406063,destabilizing
+HNRNPD,CNGB1,0.13731482200525932,destabilizing
+HNRNPD,FMN2,0.1081379916266771,destabilizing
+HNRNPD,ENSG00000228222,0.18854610128764315,destabilizing
+HNRNPD,ATXN1,0.057824434598588006,destabilizing
+HNRNPD,SYN3,0.08405282888816727,destabilizing
+HNRNPD,PRKN,0.12498017886146631,destabilizing
+HNRNPD,RASA2,0.18630791246636944,destabilizing
+HNRNPD,PPP1R12B,0.08523153450023811,destabilizing
+HNRNPD,FRMD4A,0.0883380015887638,destabilizing
+HNRNPD,CAMK1D,0.06090756453754051,destabilizing
+HNRNPD,SEMA6D,0.13458392189214147,destabilizing
+HNRNPD,WIPF2,0.15616436051869914,destabilizing
+HNRNPD,DLEU1,0.182456758671819,destabilizing
+HNRNPD,TSHZ2,0.09578600371616819,destabilizing
+HNRNPD,MED13L,0.07416394458660909,destabilizing
+HNRNPD,KAZN,0.1109734714649752,destabilizing
+HNRNPD,KANSL1,0.0674875935812786,destabilizing
+HNRNPD,FRMD5,0.12914981826207064,destabilizing
+HNRNPD,LINC00174,0.15770406398714298,destabilizing
+HNRNPD,PPM1E,0.0879648417135251,destabilizing
+HNRNPD,ARL3,0.12495034621548043,destabilizing
+HNRNPD,MBD5,0.1131643627973004,destabilizing
+HNRNPD,ELAVL3,0.14343698465426447,destabilizing
+HNRNPD,SLIT2,0.13725186224662056,destabilizing
+HNRNPD,CLASP1,0.11813386190734092,destabilizing
+HNRNPD,UNC5C,0.14482182879352662,destabilizing
+HNRNPD,NEGR1,0.1815474607908587,destabilizing
+HNRNPD,ENOX1,0.19948496304542013,destabilizing
+HNRNPD,GPHN,0.09371254394552006,destabilizing
+HNRNPD,NAV3,0.13402523777050457,destabilizing
+HNRNPD,EBF1,0.06472796014367235,destabilizing
+HNRNPD,TOMM22,0.16430343688765203,destabilizing
+HNRNPD,ANKFN1,0.08339765019239388,destabilizing
+HNRNPD,MAGI2,0.06798522417653453,destabilizing
+HNRNPD,LSAMP,0.0981128033212974,destabilizing
+HNRNPD,AKAP6,0.13964219754573673,destabilizing
+HNRNPD,ZBTB20,0.13878341974160083,destabilizing
+HNRNPD,GRIK2,0.1010248564070164,destabilizing
+HNRNPD,SOX5,0.07865421822762825,destabilizing
+HNRNPD,LRRC37A3,0.18619915536857368,destabilizing
+HNRNPD,TMEM132C,0.05203913002548147,destabilizing
+HNRNPD,EYS,0.10707304519590927,destabilizing
+HNRNPD,ARID1B,0.08541830511131002,destabilizing
+HNRNPD,RBFOX1,-0.08386483143407142,stabilizing
+HNRNPD,SDK1,0.06496222023691274,destabilizing
+HNRNPD,MLLT3,0.23744332286067996,destabilizing
+HNRNPD,FMN1,0.06250162102544475,destabilizing
+HNRNPD,ADGRB3,0.09309139170117606,destabilizing
+HNRNPD,ROBO1,0.0872313233192264,destabilizing
+HNRNPD,SYPL1,0.10161711819620811,destabilizing
+HNRNPD,PTPRD,0.1270352102414079,destabilizing
+HNRNPD,FAM155A,0.15620483273366512,destabilizing
+HNRNPD,LARP1B,0.12585011919084185,destabilizing
+HNRNPF,TRERF1,0.13298883645378934,destabilizing
+HNRNPF,SORCS1,0.08728816219346798,destabilizing
+HNRNPF,NCOA1,0.058975821378284124,destabilizing
+HNRNPF,COPA,0.06262724497256379,destabilizing
+HNRNPF,FCHSD2,0.06499944308867557,destabilizing
+HNRNPF,PDE3A,0.11272613772774216,destabilizing
+HNRNPF,UNC79,0.1419498495597709,destabilizing
+HNRNPF,DOC2B,0.1066215804687667,destabilizing
+HNRNPF,TMTC2,0.16408701101427942,destabilizing
+HNRNPF,KALRN,0.08678628630379413,destabilizing
+HNRNPF,CHD1,0.0805101456732948,destabilizing
+HNRNPF,UBE2E2,0.07882417776104587,destabilizing
+HNRNPF,PPARD,0.08762962026721687,destabilizing
+HNRNPF,TOX,0.07857521897367795,destabilizing
+HNRNPF,BRAF,0.0726760256990723,destabilizing
+HNRNPF,RYR2,0.15270048454416663,destabilizing
+HNRNPF,MTMR7,0.17916189801609586,destabilizing
+HNRNPF,EPB41L4B,0.07676233796210663,destabilizing
+HNRNPF,CACNA1B,0.09968316039605005,destabilizing
+HNRNPF,LRRTM4,0.09015205716912068,destabilizing
+HNRNPF,SIRPA,0.09998741521772586,destabilizing
+HNRNPF,FRY,0.14995646975594676,destabilizing
+HNRNPF,RUNX1T1,0.06544776450805345,destabilizing
+HNRNPF,MACROD2,0.14370794772158796,destabilizing
+HNRNPF,SHANK2,0.15573836157793985,destabilizing
+HNRNPF,CDK12,0.19333449100865133,destabilizing
+HNRNPF,RFX7,0.12657003599024494,destabilizing
+HNRNPF,JARID2,0.06316615704740416,destabilizing
+HNRNPF,MPHOSPH8,0.12576151349305728,destabilizing
+HNRNPF,DIP2C,0.08343187861739716,destabilizing
+HNRNPF,MGAT5,0.05234019200990349,destabilizing
+HNRNPF,DLG2,0.1096587995231129,destabilizing
+HNRNPF,CHST12,0.20324149497475805,destabilizing
+HNRNPF,EML5,0.1550374800164195,destabilizing
+HNRNPF,CENPP,0.24221304759728335,destabilizing
+HNRNPF,PSME4,0.13830448195655728,destabilizing
+HNRNPF,TMEM106B,0.1456547883958764,destabilizing
+HNRNPF,EPHA5,0.1348496052528239,destabilizing
+HNRNPF,KCNB2,0.15440546615013,destabilizing
+HNRNPF,ZNF83,0.10298867907633033,destabilizing
+HNRNPF,SOX6,0.09305927360123963,destabilizing
+HNRNPF,ZNF521,0.0978426247479185,destabilizing
+HNRNPF,PLEKHA5,0.08355421978072673,destabilizing
+HNRNPF,NOVA1,0.1447373648354119,destabilizing
+HNRNPF,CCNY,0.1318828969031873,destabilizing
+HNRNPF,ARIH1,0.10839135282009042,destabilizing
+HNRNPF,EPB41L5,0.07882021575869341,destabilizing
+HNRNPF,GPR158,0.12516345034188645,destabilizing
+HNRNPF,NCOA2,0.08811530535630482,destabilizing
+HNRNPF,ALK,0.20650543992418066,destabilizing
+HNRNPF,CTNND2,0.05598549370974546,destabilizing
+HNRNPF,IFT172,0.14850512029113538,destabilizing
+HNRNPF,CCNT1,0.08551894192592815,destabilizing
+HNRNPF,DTWD2,0.2118766834878109,destabilizing
+HNRNPF,SIK3,0.11111881651456082,destabilizing
+HNRNPF,CPEB3,0.15960306339324953,destabilizing
+HNRNPF,CADM2,0.06502661013318803,destabilizing
+HNRNPF,XKR6,0.13454877602446427,destabilizing
+HNRNPF,CADPS,0.07291171790562338,destabilizing
+HNRNPF,TCF20,0.12950144346185807,destabilizing
+HNRNPF,CDKAL1,0.08633574448077617,destabilizing
+HNRNPF,DGKI,0.11586527406708604,destabilizing
+HNRNPF,EXOC6B,0.1808486376355466,destabilizing
+HNRNPF,MAGI3,0.14973421921643548,destabilizing
+HNRNPF,SBF2,0.06896226966297177,destabilizing
+HNRNPF,INPP4B,0.08340182129264805,destabilizing
+HNRNPF,PTPRS,0.12202911616837088,destabilizing
+HNRNPF,CBFA2T2,0.055961654606707115,destabilizing
+HNRNPF,SPDYE3,0.11454542907548904,destabilizing
+HNRNPF,TMEM178B,0.06254965670135004,destabilizing
+HNRNPF,DMD,0.17712147162865494,destabilizing
+HNRNPF,MCU,0.11644092841388697,destabilizing
+HNRNPF,SSH2,0.1147039400509405,destabilizing
+HNRNPF,DOCK3,0.16799284161552228,destabilizing
+HNRNPF,HS6ST3,0.11387140923517858,destabilizing
+HNRNPF,LPP,0.11535067832543262,destabilizing
+HNRNPF,STAG1,0.11493779723586177,destabilizing
+HNRNPF,CAPZA2,0.13266876270931477,destabilizing
+HNRNPF,ADGRL3,0.06161428514765191,destabilizing
+HNRNPF,PHACTR1,0.0842147880763383,destabilizing
+HNRNPF,UBE2R2,0.1152561166115015,destabilizing
+HNRNPF,GTF2IRD1,0.08410545605184787,destabilizing
+HNRNPF,CCBE1,0.05560108710795591,destabilizing
+HNRNPF,TTC28,0.09296009854776412,destabilizing
+HNRNPF,RIMS2,0.10032575500850836,destabilizing
+HNRNPF,IGF1R,0.05474695995298173,destabilizing
+HNRNPF,BTBD9,0.12414689915234581,destabilizing
+HNRNPF,CNGB1,0.11746879519280612,destabilizing
+HNRNPF,FMN2,0.10924785173897479,destabilizing
+HNRNPF,ENSG00000228222,0.21975678524724326,destabilizing
+HNRNPF,SYN3,0.06590660827033887,destabilizing
+HNRNPF,PRKN,0.1050510374140874,destabilizing
+HNRNPF,RASA2,0.1377656590681576,destabilizing
+HNRNPF,PPP1R12B,0.10351386168851007,destabilizing
+HNRNPF,FRMD4A,0.11529752260586149,destabilizing
+HNRNPF,CAMK1D,0.060478735543318944,destabilizing
+HNRNPF,SEMA6D,0.11055258203732589,destabilizing
+HNRNPF,WIPF2,0.1434875518095493,destabilizing
+HNRNPF,DLEU1,0.20752230435952682,destabilizing
+HNRNPF,TSHZ2,0.08472284268207562,destabilizing
+HNRNPF,KAZN,0.08458202614994335,destabilizing
+HNRNPF,KANSL1,0.0986503350315507,destabilizing
+HNRNPF,FRMD5,0.12449583610594597,destabilizing
+HNRNPF,LINC00174,0.11463308458205204,destabilizing
+HNRNPF,PPM1E,0.0990874800191819,destabilizing
+HNRNPF,ARL3,0.09501028992723803,destabilizing
+HNRNPF,MBD5,0.10352028713271134,destabilizing
+HNRNPF,ELAVL3,0.10867944572317219,destabilizing
+HNRNPF,SLIT2,0.16919728900674808,destabilizing
+HNRNPF,CLASP1,0.11373545233990943,destabilizing
+HNRNPF,UNC5C,0.12363614437870912,destabilizing
+HNRNPF,CACNA2D3,-0.05214600512347681,stabilizing
+HNRNPF,RC3H1,0.07399402609927398,destabilizing
+HNRNPF,NEGR1,0.1314259058782848,destabilizing
+HNRNPF,ENOX1,0.15508121076496964,destabilizing
+HNRNPF,GPHN,0.09443029263270877,destabilizing
+HNRNPF,NAV3,0.141700273398321,destabilizing
+HNRNPF,TOMM22,0.11241495915817377,destabilizing
+HNRNPF,ANKFN1,0.05707571399446222,destabilizing
+HNRNPF,MAGI2,0.05539560277842859,destabilizing
+HNRNPF,LSAMP,0.09107507581101412,destabilizing
+HNRNPF,AKAP6,0.1348929796472077,destabilizing
+HNRNPF,TMED2,0.10596706964388898,destabilizing
+HNRNPF,ZBTB20,0.12083994781519923,destabilizing
+HNRNPF,GRIK2,0.10880870187975972,destabilizing
+HNRNPF,SOX5,0.08788235406020568,destabilizing
+HNRNPF,LRRC37A3,0.16792608255432886,destabilizing
+HNRNPF,EYS,0.085326299851273,destabilizing
+HNRNPF,ARID1B,0.07805577422995819,destabilizing
+HNRNPF,PRKCE,0.09315091090264462,destabilizing
+HNRNPF,RBFOX1,-0.07236873410191941,stabilizing
+HNRNPF,SDK1,0.06579766005912682,destabilizing
+HNRNPF,NRG1,0.05423022286269809,destabilizing
+HNRNPF,MLLT3,0.17987390833877065,destabilizing
+HNRNPF,FMN1,0.08839780650869913,destabilizing
+HNRNPF,ADGRB3,0.0767170173288868,destabilizing
+HNRNPF,ROBO1,0.08277783461801945,destabilizing
+HNRNPF,SYPL1,0.08741007713931692,destabilizing
+HNRNPF,PTPRD,0.101401575476632,destabilizing
+HNRNPF,FAM155A,0.13814431361327306,destabilizing
+HNRNPF,LARP1B,0.1280482224453025,destabilizing
+HNRNPH1,SORCS1,0.07145949408476807,destabilizing
+HNRNPH1,UNC79,0.07935446486736979,destabilizing
+HNRNPH1,MACROD2,0.07155088785163917,destabilizing
+HNRNPH1,SHANK2,0.11670820918269116,destabilizing
+HNRNPH1,KCNB2,0.1047094907428536,destabilizing
+HNRNPH1,EXOC6B,0.09541826300618952,destabilizing
+HNRNPH1,MAGI3,0.07919302431573565,destabilizing
+HNRNPH1,DMD,0.07921177022053769,destabilizing
+HNRNPH1,GTF2IRD1,0.06655435193864509,destabilizing
+HNRNPH1,WIPF2,0.07798705506138875,destabilizing
+HNRNPH1,FRMD5,0.07326509548061458,destabilizing
+HNRNPH1,SLIT2,0.08679744433386062,destabilizing
+HNRNPH1,LRRC37A3,0.07916422745144308,destabilizing
+HNRNPH1,EYS,0.05434529728555894,destabilizing
+HNRNPH1,RBFOX1,-0.06490199365265828,stabilizing
+HNRNPK,TRERF1,0.19831411597288126,destabilizing
+HNRNPK,SORCS1,0.09891835322316737,destabilizing
+HNRNPK,COPA,0.07845256314791432,destabilizing
+HNRNPK,FCHSD2,0.08455372429513547,destabilizing
+HNRNPK,PDE3A,0.15547927932295968,destabilizing
+HNRNPK,UNC79,0.1669210802264425,destabilizing
+HNRNPK,DOC2B,0.13567624844941867,destabilizing
+HNRNPK,TMTC2,0.1917835630050624,destabilizing
+HNRNPK,KALRN,0.12247582191715355,destabilizing
+HNRNPK,CHD1,0.07084201318640398,destabilizing
+HNRNPK,UBE2E2,0.0627521390467147,destabilizing
+HNRNPK,PPARD,0.09124591952986313,destabilizing
+HNRNPK,TOX,0.0915731247290727,destabilizing
+HNRNPK,BRAF,0.05837198543656205,destabilizing
+HNRNPK,RYR2,0.1836398727620074,destabilizing
+HNRNPK,MTMR7,0.20144516177299934,destabilizing
+HNRNPK,EIF4E,0.2366732574467138,destabilizing
+HNRNPK,SOX11,0.06632092022647887,destabilizing
+HNRNPK,EPB41L4B,0.08373146829980667,destabilizing
+HNRNPK,CACNA1B,0.1275098093949301,destabilizing
+HNRNPK,TBC1D5,0.0667381421087806,destabilizing
+HNRNPK,WSB1,0.05241493628284217,destabilizing
+HNRNPK,LRRTM4,0.0820212905769425,destabilizing
+HNRNPK,PTEN,0.12428389331550004,destabilizing
+HNRNPK,FRY,0.20647548811409913,destabilizing
+HNRNPK,RUNX1T1,0.07857418565876217,destabilizing
+HNRNPK,MACROD2,0.1648262542081091,destabilizing
+HNRNPK,SHANK2,0.19914108395265412,destabilizing
+HNRNPK,CDK12,0.267578593969612,destabilizing
+HNRNPK,RFX7,0.17297896981676442,destabilizing
+HNRNPK,UBR5,0.06324226151429724,destabilizing
+HNRNPK,JARID2,0.08026772270411092,destabilizing
+HNRNPK,MPHOSPH8,0.19094677919879446,destabilizing
+HNRNPK,DIP2C,0.09955910931965574,destabilizing
+HNRNPK,UBR3,0.09528542767103364,destabilizing
+HNRNPK,DLG2,0.11095336299050663,destabilizing
+HNRNPK,CHST12,0.29818916910818855,destabilizing
+HNRNPK,EML5,0.16957792918300604,destabilizing
+HNRNPK,CENPP,0.2949071549468914,destabilizing
+HNRNPK,PSME4,0.12095894128996787,destabilizing
+HNRNPK,TMEM106B,0.16795952449634832,destabilizing
+HNRNPK,EPHA5,0.1305688791997858,destabilizing
+HNRNPK,KCNB2,0.25517307079642726,destabilizing
+HNRNPK,ZNF83,0.15752213442953406,destabilizing
+HNRNPK,SOX6,0.13333231329109677,destabilizing
+HNRNPK,ZNF521,0.17316873837972505,destabilizing
+HNRNPK,PLEKHA5,0.10423886679968618,destabilizing
+HNRNPK,NOVA1,0.21939604062083662,destabilizing
+HNRNPK,CCNY,0.15981618177712287,destabilizing
+HNRNPK,ARIH1,0.10769849710386069,destabilizing
+HNRNPK,EPB41L5,0.10068321038438084,destabilizing
+HNRNPK,GPR158,0.1389766839674793,destabilizing
+HNRNPK,NCOA2,0.09521574716042487,destabilizing
+HNRNPK,MARCKS,0.09828993034467408,destabilizing
+HNRNPK,ALK,0.2781127541456192,destabilizing
+HNRNPK,ACACA,0.05920510428863448,destabilizing
+HNRNPK,IFT172,0.1742560725861521,destabilizing
+HNRNPK,CCNT1,0.12583124763851894,destabilizing
+HNRNPK,DTWD2,0.307585672813,destabilizing
+HNRNPK,SIK3,0.12500905418069982,destabilizing
+HNRNPK,CPEB3,0.21763960812295222,destabilizing
+HNRNPK,CADM2,0.07836070899939786,destabilizing
+HNRNPK,XKR6,0.21016724485506616,destabilizing
+HNRNPK,RMND5A,0.06873527754610442,destabilizing
+HNRNPK,CADPS,0.10889138791023872,destabilizing
+HNRNPK,FGF13,0.07926461185215161,destabilizing
+HNRNPK,TCF20,0.13225745732818192,destabilizing
+HNRNPK,CDKAL1,0.10597948806559904,destabilizing
+HNRNPK,DGKI,0.1339359654005452,destabilizing
+HNRNPK,EXOC6B,0.20305459187679942,destabilizing
+HNRNPK,MAGI3,0.1809207183779179,destabilizing
+HNRNPK,SBF2,0.09960396755184898,destabilizing
+HNRNPK,INPP4B,0.127601671831602,destabilizing
+HNRNPK,PTPRS,0.177453573234624,destabilizing
+HNRNPK,CBFA2T2,0.07372203072959875,destabilizing
+HNRNPK,SPDYE3,0.10879994293600481,destabilizing
+HNRNPK,TMEM178B,0.07687026642462802,destabilizing
+HNRNPK,DMD,0.23393582597900714,destabilizing
+HNRNPK,EIF4G3,0.07555933882283132,destabilizing
+HNRNPK,MCU,0.10283278301286773,destabilizing
+HNRNPK,SSH2,0.1293329938909729,destabilizing
+HNRNPK,DOCK3,0.19075747457183875,destabilizing
+HNRNPK,HS6ST3,0.11118495840517735,destabilizing
+HNRNPK,LPP,0.1280444044275936,destabilizing
+HNRNPK,STAG1,0.13221934614809563,destabilizing
+HNRNPK,CAPZA2,0.18614935495269494,destabilizing
+HNRNPK,ADGRL3,0.06856145886632811,destabilizing
+HNRNPK,PHACTR1,0.11551295904808358,destabilizing
+HNRNPK,UBE2R2,0.1719560690294296,destabilizing
+HNRNPK,GTF2IRD1,0.09605863690487529,destabilizing
+HNRNPK,VAPA,0.06504999067336227,destabilizing
+HNRNPK,JMJD1C,0.07800378577423162,destabilizing
+HNRNPK,TTC28,0.13106098852861556,destabilizing
+HNRNPK,SBNO1,0.07838995770895653,destabilizing
+HNRNPK,RIMS2,0.11167596607149749,destabilizing
+HNRNPK,BTBD9,0.11290580620974278,destabilizing
+HNRNPK,CNGB1,0.168993045161157,destabilizing
+HNRNPK,FMN2,0.1030162434203527,destabilizing
+HNRNPK,ENSG00000228222,0.26823210392086666,destabilizing
+HNRNPK,SYN3,0.08707822307550125,destabilizing
+HNRNPK,PRKN,0.13840485983609138,destabilizing
+HNRNPK,RASA2,0.21020536900769363,destabilizing
+HNRNPK,PPP1R12B,0.10846375113366004,destabilizing
+HNRNPK,FRMD4A,0.11030906244190557,destabilizing
+HNRNPK,SEMA6D,0.14249666664691737,destabilizing
+HNRNPK,WIPF2,0.18548619650096348,destabilizing
+HNRNPK,DLEU1,0.2280950936662628,destabilizing
+HNRNPK,TSHZ2,0.09621365601607099,destabilizing
+HNRNPK,MED13L,0.08289171286847147,destabilizing
+HNRNPK,KAZN,0.10914271458165123,destabilizing
+HNRNPK,KANSL1,0.08946998715816332,destabilizing
+HNRNPK,FRMD5,0.13598756019900637,destabilizing
+HNRNPK,LINC00174,0.2088013188316561,destabilizing
+HNRNPK,PPM1E,0.11433040506263867,destabilizing
+HNRNPK,ARL3,0.15279561108120307,destabilizing
+HNRNPK,MBD5,0.14757678295747212,destabilizing
+HNRNPK,ELAVL3,0.17671522310204915,destabilizing
+HNRNPK,SLIT2,0.17886294036234632,destabilizing
+HNRNPK,CLASP1,0.10922412029917734,destabilizing
+HNRNPK,UNC5C,0.1667420056756561,destabilizing
+HNRNPK,RC3H1,0.0818186956784302,destabilizing
+HNRNPK,NEGR1,0.19010680957433454,destabilizing
+HNRNPK,ENOX1,0.22035700791071786,destabilizing
+HNRNPK,SCUBE1,0.10635841435459192,destabilizing
+HNRNPK,GPHN,0.08399413845913702,destabilizing
+HNRNPK,NAV3,0.15437414002382333,destabilizing
+HNRNPK,EBF1,0.056867238073743304,destabilizing
+HNRNPK,TOMM22,0.21335896749884561,destabilizing
+HNRNPK,MBNL2,0.054690843574211986,destabilizing
+HNRNPK,ANKFN1,0.08677280099002707,destabilizing
+HNRNPK,MAGI2,0.062086506754071145,destabilizing
+HNRNPK,LSAMP,0.1131291329771985,destabilizing
+HNRNPK,AKAP6,0.1339447885154207,destabilizing
+HNRNPK,TMED2,0.15823361850136516,destabilizing
+HNRNPK,ZBTB20,0.14599716944654442,destabilizing
+HNRNPK,GRIK2,0.11860344900683499,destabilizing
+HNRNPK,SOX5,0.09995891456271767,destabilizing
+HNRNPK,LRRC37A3,0.216979450955858,destabilizing
+HNRNPK,TMEM132C,0.05746920933725517,destabilizing
+HNRNPK,EYS,0.12359885089206117,destabilizing
+HNRNPK,ARID1B,0.07632444395158001,destabilizing
+HNRNPK,PRKCE,0.08027517878425851,destabilizing
+HNRNPK,RBFOX1,-0.0718540462651609,stabilizing
+HNRNPK,SDK1,0.06500804257360845,destabilizing
+HNRNPK,NRG1,0.07349642629170965,destabilizing
+HNRNPK,RORA,0.07709055943832997,destabilizing
+HNRNPK,MLLT3,0.28925766081138593,destabilizing
+HNRNPK,ROBO1,0.07522811760258148,destabilizing
+HNRNPK,SYPL1,0.1093073932632251,destabilizing
+HNRNPK,PTPRD,0.15373587679530967,destabilizing
+HNRNPK,FAM155A,0.18275073552933915,destabilizing
+HNRNPK,LARP1B,0.11782546455845289,destabilizing
+HNRNPL,CDK12,0.09400475937175365,destabilizing
+HNRNPL,MLLT3,0.0963383037194568,destabilizing
+HNRNPM,TRERF1,0.1115983182329272,destabilizing
+HNRNPM,SORCS1,0.06425337026569863,destabilizing
+HNRNPM,PDE3A,0.1049101919939698,destabilizing
+HNRNPM,UNC79,0.13411233603224199,destabilizing
+HNRNPM,DOC2B,0.08685252903058786,destabilizing
+HNRNPM,TMTC2,0.1117834104237227,destabilizing
+HNRNPM,KALRN,0.0795843013958462,destabilizing
+HNRNPM,UBE2E2,0.061861760128170296,destabilizing
+HNRNPM,BRAF,0.0518561961232194,destabilizing
+HNRNPM,RYR2,0.12656378254678843,destabilizing
+HNRNPM,MTMR7,0.1359386258877664,destabilizing
+HNRNPM,EIF4E,0.13313235047220692,destabilizing
+HNRNPM,CACNA1B,0.07672598472844773,destabilizing
+HNRNPM,LRRTM4,0.06742525163252612,destabilizing
+HNRNPM,PTEN,0.08375218573481667,destabilizing
+HNRNPM,FRY,0.13583116785803842,destabilizing
+HNRNPM,RUNX1T1,0.06388584012981013,destabilizing
+HNRNPM,MACROD2,0.10830939230726291,destabilizing
+HNRNPM,SHANK2,0.11988373532315634,destabilizing
+HNRNPM,CDK12,0.1813283395616649,destabilizing
+HNRNPM,RFX7,0.11797741267389576,destabilizing
+HNRNPM,MPHOSPH8,0.13157071397344322,destabilizing
+HNRNPM,DLG2,0.08388626292940171,destabilizing
+HNRNPM,CHST12,0.1957794313846208,destabilizing
+HNRNPM,EML5,0.0874838201095245,destabilizing
+HNRNPM,CENPP,0.2669635728896386,destabilizing
+HNRNPM,PSME4,0.07537458126901607,destabilizing
+HNRNPM,TMEM106B,0.0940806627891351,destabilizing
+HNRNPM,EPHA5,0.08784985659966811,destabilizing
+HNRNPM,KCNB2,0.16166579931512706,destabilizing
+HNRNPM,SOX6,0.08220306390773849,destabilizing
+HNRNPM,ZNF521,0.1339679304545678,destabilizing
+HNRNPM,PLEKHA5,0.07492758210428878,destabilizing
+HNRNPM,NOVA1,0.15446538118330658,destabilizing
+HNRNPM,CCNY,0.12226558196434226,destabilizing
+HNRNPM,ARIH1,0.07398731373480162,destabilizing
+HNRNPM,EPB41L5,0.05822479850277335,destabilizing
+HNRNPM,GPR158,0.08913800694117566,destabilizing
+HNRNPM,NCOA2,0.06523172799684597,destabilizing
+HNRNPM,MARCKS,0.05462107148023628,destabilizing
+HNRNPM,ALK,0.20578328317784636,destabilizing
+HNRNPM,IFT172,0.12149049732772856,destabilizing
+HNRNPM,CCNT1,0.08188512560346281,destabilizing
+HNRNPM,DTWD2,0.2304837144939883,destabilizing
+HNRNPM,CPEB3,0.1439126570028395,destabilizing
+HNRNPM,CADM2,0.06813683913172258,destabilizing
+HNRNPM,XKR6,0.12684943965579162,destabilizing
+HNRNPM,TCF20,0.0854657630803875,destabilizing
+HNRNPM,CDKAL1,0.07026482177817575,destabilizing
+HNRNPM,DGKI,0.09518980963964624,destabilizing
+HNRNPM,EXOC6B,0.1257711158075305,destabilizing
+HNRNPM,MAGI3,0.11661381885386064,destabilizing
+HNRNPM,INPP4B,0.079913351242691,destabilizing
+HNRNPM,PTPRS,0.14799705040895533,destabilizing
+HNRNPM,DMD,0.14956789990412456,destabilizing
+HNRNPM,MCU,0.07744012548788223,destabilizing
+HNRNPM,SSH2,0.10872927605853609,destabilizing
+HNRNPM,DOCK3,0.1534386993375542,destabilizing
+HNRNPM,HS6ST3,0.09053948212235824,destabilizing
+HNRNPM,STAG1,0.0723193597818627,destabilizing
+HNRNPM,CAPZA2,0.1424077275154364,destabilizing
+HNRNPM,ADGRL3,0.05940250760513097,destabilizing
+HNRNPM,PHACTR1,0.0739240540403323,destabilizing
+HNRNPM,UBE2R2,0.12365460899382426,destabilizing
+HNRNPM,GTF2IRD1,0.06836868522746653,destabilizing
+HNRNPM,TTC28,0.08751298409241016,destabilizing
+HNRNPM,RIMS2,0.09071856136393386,destabilizing
+HNRNPM,BTBD9,0.09845065491516093,destabilizing
+HNRNPM,CNGB1,0.12379786481636916,destabilizing
+HNRNPM,FMN2,0.071299546120774,destabilizing
+HNRNPM,ENSG00000228222,0.15561041119530353,destabilizing
+HNRNPM,SYN3,0.055631572821169345,destabilizing
+HNRNPM,PRKN,0.11305900625489695,destabilizing
+HNRNPM,RASA2,0.14326553205110304,destabilizing
+HNRNPM,FRMD4A,0.06418726624751839,destabilizing
+HNRNPM,SEMA6D,0.10084978077922795,destabilizing
+HNRNPM,WIPF2,0.12051674830953966,destabilizing
+HNRNPM,DLEU1,0.1443000017944373,destabilizing
+HNRNPM,TSHZ2,0.05531040595010118,destabilizing
+HNRNPM,FRMD5,0.07631900970192758,destabilizing
+HNRNPM,LINC00174,0.13590414457532524,destabilizing
+HNRNPM,ARL3,0.09592217337986099,destabilizing
+HNRNPM,MBD5,0.09021587058676804,destabilizing
+HNRNPM,ELAVL3,0.11096062183506729,destabilizing
+HNRNPM,SLIT2,0.12121088585286821,destabilizing
+HNRNPM,CLASP1,0.07575429400162086,destabilizing
+HNRNPM,UNC5C,0.09696081897572793,destabilizing
+HNRNPM,NEGR1,0.14577561365873973,destabilizing
+HNRNPM,ENOX1,0.16333293812004165,destabilizing
+HNRNPM,GPHN,0.0739229018295113,destabilizing
+HNRNPM,NAV3,0.11639954645334194,destabilizing
+HNRNPM,TOMM22,0.13208480468994882,destabilizing
+HNRNPM,ANKFN1,0.06921536445467326,destabilizing
+HNRNPM,LSAMP,0.059570056521427786,destabilizing
+HNRNPM,AKAP6,0.0668413230895684,destabilizing
+HNRNPM,TMED2,0.08929134683758203,destabilizing
+HNRNPM,ZBTB20,0.10460719695698001,destabilizing
+HNRNPM,GRIK2,0.08043386379991453,destabilizing
+HNRNPM,LRRC37A3,0.16969073838244053,destabilizing
+HNRNPM,TMEM132C,0.05555086039747214,destabilizing
+HNRNPM,EYS,0.08214888797082515,destabilizing
+HNRNPM,ARID1B,0.05719145934401087,destabilizing
+HNRNPM,RBFOX1,-0.051557743561089255,stabilizing
+HNRNPM,MLLT3,0.19278372122138285,destabilizing
+HNRNPM,SYPL1,0.07440799465409298,destabilizing
+HNRNPM,PTPRD,0.09079461966167507,destabilizing
+HNRNPM,FAM155A,0.1368479337059462,destabilizing
+HNRNPM,LARP1B,0.08580554697547846,destabilizing
+HNRNPU,TRERF1,0.11909544719780628,destabilizing
+HNRNPU,SORCS1,0.07436769107815641,destabilizing
+HNRNPU,UNC79,0.10623736830222116,destabilizing
+HNRNPU,DOC2B,0.0813886433790371,destabilizing
+HNRNPU,TMTC2,0.11192128353261174,destabilizing
+HNRNPU,TOX,0.09012659764228212,destabilizing
+HNRNPU,RYR2,0.12979941180945065,destabilizing
+HNRNPU,MTMR7,0.14196736350694508,destabilizing
+HNRNPU,EIF4E,0.14688674648406205,destabilizing
+HNRNPU,CACNA1B,0.06197953229689015,destabilizing
+HNRNPU,LRRTM4,0.061358605011787096,destabilizing
+HNRNPU,FRY,0.15164066400319168,destabilizing
+HNRNPU,MACROD2,0.11907914601922115,destabilizing
+HNRNPU,SHANK2,0.14131155241218585,destabilizing
+HNRNPU,CDK12,0.15199838705909707,destabilizing
+HNRNPU,RFX7,0.1276552173620248,destabilizing
+HNRNPU,MPHOSPH8,0.08781384093679387,destabilizing
+HNRNPU,DLG2,0.06930909563721441,destabilizing
+HNRNPU,CHST12,0.12411374722786786,destabilizing
+HNRNPU,EML5,0.10678647189488463,destabilizing
+HNRNPU,CENPP,0.25716301738930725,destabilizing
+HNRNPU,PSME4,0.08834711250824828,destabilizing
+HNRNPU,TMEM106B,0.08456164848173954,destabilizing
+HNRNPU,EPHA5,0.10335312023347965,destabilizing
+HNRNPU,KCNB2,0.15640650075560664,destabilizing
+HNRNPU,ZNF83,0.07694095598995829,destabilizing
+HNRNPU,SOX6,0.07209164257450353,destabilizing
+HNRNPU,ZNF521,0.07176760127880563,destabilizing
+HNRNPU,DTL,-0.0989350377984482,stabilizing
+HNRNPU,NOVA1,0.11148961582944823,destabilizing
+HNRNPU,CCNY,0.10030851362655506,destabilizing
+HNRNPU,ARIH1,0.07308297420235176,destabilizing
+HNRNPU,GPR158,0.11032467613379042,destabilizing
+HNRNPU,ALK,0.23844477317290755,destabilizing
+HNRNPU,IFT172,0.11720545955315112,destabilizing
+HNRNPU,CCNT1,0.05584593167509254,destabilizing
+HNRNPU,DTWD2,0.174871274542908,destabilizing
+HNRNPU,SIK3,0.1005476174739993,destabilizing
+HNRNPU,CPEB3,0.12610853252553572,destabilizing
+HNRNPU,XKR6,0.1342364508009606,destabilizing
+HNRNPU,CADPS,0.06231387511810726,destabilizing
+HNRNPU,CDKAL1,0.06526136417670456,destabilizing
+HNRNPU,DGKI,0.09749018359145162,destabilizing
+HNRNPU,EXOC6B,0.11171044720224484,destabilizing
+HNRNPU,MAGI3,0.12426734327759571,destabilizing
+HNRNPU,DMD,0.1624334657715133,destabilizing
+HNRNPU,MCU,0.08305691337483277,destabilizing
+HNRNPU,SSH2,0.08573464182265508,destabilizing
+HNRNPU,DOCK3,0.11870307669392675,destabilizing
+HNRNPU,CAPZA2,0.10992969017244927,destabilizing
+HNRNPU,PHACTR1,0.08109838268962016,destabilizing
+HNRNPU,GTF2IRD1,0.08373364017753238,destabilizing
+HNRNPU,CNGB1,0.08361172251607461,destabilizing
+HNRNPU,FMN2,0.06288968451160154,destabilizing
+HNRNPU,ENSG00000228222,0.17022456800325797,destabilizing
+HNRNPU,SYN3,0.0753651557418645,destabilizing
+HNRNPU,PRKN,0.103300674073411,destabilizing
+HNRNPU,RASA2,0.09692617789388426,destabilizing
+HNRNPU,CAMK1D,0.06090627208049326,destabilizing
+HNRNPU,SEMA6D,0.08367970409667166,destabilizing
+HNRNPU,WIPF2,0.11554967806186274,destabilizing
+HNRNPU,DLEU1,0.13369538214382387,destabilizing
+HNRNPU,TSHZ2,0.062526905888037,destabilizing
+HNRNPU,KANSL1,0.07235205460152605,destabilizing
+HNRNPU,FRMD5,0.09683025532900426,destabilizing
+HNRNPU,LINC00174,0.08413982983283338,destabilizing
+HNRNPU,ARL3,0.10087299415386129,destabilizing
+HNRNPU,MBD5,0.07154860254121051,destabilizing
+HNRNPU,ELAVL3,0.08973571366146985,destabilizing
+HNRNPU,SLIT2,0.10148945178869773,destabilizing
+HNRNPU,UNC5C,0.09390500983499321,destabilizing
+HNRNPU,NEGR1,0.11721361797886318,destabilizing
+HNRNPU,ENOX1,0.14974137471376628,destabilizing
+HNRNPU,GPHN,0.07341216788069561,destabilizing
+HNRNPU,ANKFN1,0.0565896357625958,destabilizing
+HNRNPU,AKAP6,0.06960620897019429,destabilizing
+HNRNPU,ZBTB20,0.10754592768237534,destabilizing
+HNRNPU,GRIK2,0.07412750619297073,destabilizing
+HNRNPU,LRRC37A3,0.1536134165139101,destabilizing
+HNRNPU,MLLT3,0.13751930414851984,destabilizing
+HNRNPU,SYPL1,0.0740323874867713,destabilizing
+HNRNPU,PTPRD,0.08681256664874587,destabilizing
+HNRNPU,FAM155A,0.13485395793884578,destabilizing
+HNRNPU,LARP1B,0.06198596354135521,destabilizing
+RBFOX1,TRERF1,0.1545472384595598,destabilizing
+RBFOX1,SORCS1,0.09929214769829856,destabilizing
+RBFOX1,NCOA1,0.06362544291602562,destabilizing
+RBFOX1,PDE3A,0.17659648088697377,destabilizing
+RBFOX1,UNC79,0.17759890041421114,destabilizing
+RBFOX1,DOC2B,0.1102873426006796,destabilizing
+RBFOX1,TMTC2,0.15574589778025927,destabilizing
+RBFOX1,KALRN,0.10272107284437161,destabilizing
+RBFOX1,CHD1,0.1100569700705421,destabilizing
+RBFOX1,PPARD,0.0731022682346617,destabilizing
+RBFOX1,BRAF,0.0571477560962154,destabilizing
+RBFOX1,MTMR7,0.1686378419814146,destabilizing
+RBFOX1,EIF4E,0.13082736307564274,destabilizing
+RBFOX1,SOX11,0.07077111273682642,destabilizing
+RBFOX1,EPB41L4B,0.11490625286709232,destabilizing
+RBFOX1,CACNA1B,0.10466011127898188,destabilizing
+RBFOX1,TBC1D5,0.06679861408829742,destabilizing
+RBFOX1,LRRTM4,0.12496932368039942,destabilizing
+RBFOX1,SIRPA,0.14591553332789273,destabilizing
+RBFOX1,PTEN,0.11089400099523844,destabilizing
+RBFOX1,FRY,0.13806454835014279,destabilizing
+RBFOX1,MACROD2,0.15568505617225042,destabilizing
+RBFOX1,FOXN3,0.05928102041761908,destabilizing
+RBFOX1,SHANK2,0.18510388759412272,destabilizing
+RBFOX1,CDK12,0.22597514324421628,destabilizing
+RBFOX1,RFX7,0.14859199257039565,destabilizing
+RBFOX1,UBR5,0.10212311618917133,destabilizing
+RBFOX1,JARID2,0.096561444703039,destabilizing
+RBFOX1,MPHOSPH8,0.11053477666265062,destabilizing
+RBFOX1,DIP2C,0.1140967957446578,destabilizing
+RBFOX1,ZNF423,0.06426372011954547,destabilizing
+RBFOX1,UBR3,0.11623365763222426,destabilizing
+RBFOX1,MGAT5,0.08783325633475889,destabilizing
+RBFOX1,DLG2,0.09174727250252551,destabilizing
+RBFOX1,CHST12,0.26168588576153584,destabilizing
+RBFOX1,EML5,0.1531269721857188,destabilizing
+RBFOX1,CENPP,0.1474570845717382,destabilizing
+RBFOX1,PSME4,0.14359640365786527,destabilizing
+RBFOX1,TMEM106B,0.1820010362784618,destabilizing
+RBFOX1,EPHA5,0.1295214644100829,destabilizing
+RBFOX1,KCNB2,0.1299117434652461,destabilizing
+RBFOX1,ZNF83,0.08981523710219069,destabilizing
+RBFOX1,SOX6,0.07637178842074945,destabilizing
+RBFOX1,ZNF521,0.13104863804851297,destabilizing
+RBFOX1,PLEKHA5,0.07392637621709704,destabilizing
+RBFOX1,DTL,0.11163322041523713,destabilizing
+RBFOX1,NOVA1,0.1686303480861222,destabilizing
+RBFOX1,CCNY,0.143353029332022,destabilizing
+RBFOX1,ARIH1,0.1175637959164402,destabilizing
+RBFOX1,EPB41L5,0.09407144105194354,destabilizing
+RBFOX1,GPR158,0.14630832802762186,destabilizing
+RBFOX1,NCOA2,0.09916867112518622,destabilizing
+RBFOX1,ALK,0.11319849646562999,destabilizing
+RBFOX1,ACACA,0.09931835858706844,destabilizing
+RBFOX1,IFT172,0.1317705414931287,destabilizing
+RBFOX1,CCNT1,0.08443814187984544,destabilizing
+RBFOX1,DTWD2,0.142935605630304,destabilizing
+RBFOX1,SIK3,0.11379753847489857,destabilizing
+RBFOX1,CPEB3,0.15418583788814008,destabilizing
+RBFOX1,CADM2,0.07064355495386278,destabilizing
+RBFOX1,XKR6,0.16244358927021565,destabilizing
+RBFOX1,CADPS,0.07269914579011344,destabilizing
+RBFOX1,FGF13,0.07063905623186609,destabilizing
+RBFOX1,TCF20,0.15156161345878916,destabilizing
+RBFOX1,DGKI,0.11527060835852274,destabilizing
+RBFOX1,EXOC6B,0.17188140600516313,destabilizing
+RBFOX1,MAGI3,0.14675114523455693,destabilizing
+RBFOX1,SBF2,0.08924508314106877,destabilizing
+RBFOX1,INPP4B,0.1486280856230231,destabilizing
+RBFOX1,PTPRS,0.15511218102402644,destabilizing
+RBFOX1,CBFA2T2,0.09186912088693201,destabilizing
+RBFOX1,SPDYE3,0.1264747275342288,destabilizing
+RBFOX1,DMD,0.20907887780120912,destabilizing
+RBFOX1,EIF4G3,0.060667649405749854,destabilizing
+RBFOX1,MCU,0.13400399373145686,destabilizing
+RBFOX1,SSH2,0.10155599577675098,destabilizing
+RBFOX1,DOCK3,0.17003969041473438,destabilizing
+RBFOX1,HS6ST3,0.14935797002056247,destabilizing
+RBFOX1,LPP,0.18875503427035667,destabilizing
+RBFOX1,STAG1,0.12102403337961622,destabilizing
+RBFOX1,CAPZA2,0.11236228958466032,destabilizing
+RBFOX1,ADGRL3,0.062072850765751045,destabilizing
+RBFOX1,UBE2R2,0.15963666220045922,destabilizing
+RBFOX1,GTF2IRD1,0.134958762839068,destabilizing
+RBFOX1,CCBE1,0.08313955276543748,destabilizing
+RBFOX1,SBNO1,0.08746202142209802,destabilizing
+RBFOX1,RIMS2,0.07790483648978246,destabilizing
+RBFOX1,IGF1R,0.054507052870570574,destabilizing
+RBFOX1,TRIO,0.0959202212976212,destabilizing
+RBFOX1,BTBD9,0.1279680300296438,destabilizing
+RBFOX1,CNGB1,0.15926436581759953,destabilizing
+RBFOX1,FMN2,0.0982856073261912,destabilizing
+RBFOX1,ENSG00000228222,0.21558927749457493,destabilizing
+RBFOX1,ATXN1,0.054373639529173345,destabilizing
+RBFOX1,PRKN,0.19190804650608295,destabilizing
+RBFOX1,RASA2,0.12061882773882329,destabilizing
+RBFOX1,PPP1R12B,0.0698527973580052,destabilizing
+RBFOX1,FRMD4A,0.13513001343354158,destabilizing
+RBFOX1,CAMK1D,0.06646511370092519,destabilizing
+RBFOX1,PARD3,0.06491825542795565,destabilizing
+RBFOX1,SEMA6D,0.1201182524529154,destabilizing
+RBFOX1,WIPF2,0.122872520620216,destabilizing
+RBFOX1,DLEU1,0.18482531977447306,destabilizing
+RBFOX1,TSHZ2,0.07487601538931822,destabilizing
+RBFOX1,MED13L,0.09612980640531622,destabilizing
+RBFOX1,KAZN,0.12678117337419656,destabilizing
+RBFOX1,KANSL1,0.06492849074091078,destabilizing
+RBFOX1,FRMD5,0.10870199596272233,destabilizing
+RBFOX1,LINC00174,0.11625773000507862,destabilizing
+RBFOX1,PPM1E,0.14110935750817585,destabilizing
+RBFOX1,ARL3,0.06340394347887422,destabilizing
+RBFOX1,MBD5,0.11636497675108767,destabilizing
+RBFOX1,ELAVL3,0.12229616602518242,destabilizing
+RBFOX1,SLIT2,0.21978817226342257,destabilizing
+RBFOX1,CLASP1,0.10431462361141189,destabilizing
+RBFOX1,DOCK4,0.06400074136983622,destabilizing
+RBFOX1,UNC5C,0.11702001719214945,destabilizing
+RBFOX1,CACNA2D3,-0.08436479423899855,stabilizing
+RBFOX1,RC3H1,0.10408828540271212,destabilizing
+RBFOX1,NEGR1,0.13030906918949928,destabilizing
+RBFOX1,ENOX1,0.18450552391302036,destabilizing
+RBFOX1,SCUBE1,0.08960091192817882,destabilizing
+RBFOX1,GPHN,0.09060330480457707,destabilizing
+RBFOX1,NAV3,0.1877320138922972,destabilizing
+RBFOX1,TOMM22,0.1546985856348792,destabilizing
+RBFOX1,MBNL2,0.06483621826976119,destabilizing
+RBFOX1,MAGI2,0.08393216106621688,destabilizing
+RBFOX1,LSAMP,0.0883137445443174,destabilizing
+RBFOX1,AKAP6,0.11895357181448785,destabilizing
+RBFOX1,TMED2,0.08102742034034897,destabilizing
+RBFOX1,ZBTB20,0.14467944969952962,destabilizing
+RBFOX1,GRIK2,0.12333020052974458,destabilizing
+RBFOX1,LRRC37A3,0.1858264625669543,destabilizing
+RBFOX1,EYS,0.08874183202853854,destabilizing
+RBFOX1,ARID1B,0.0984044841964908,destabilizing
+RBFOX1,PRKCE,0.08139154558796938,destabilizing
+RBFOX1,RBFOX1,-0.43631944765007097,stabilizing
+RBFOX1,SDK1,0.08395368962359363,destabilizing
+RBFOX1,NRG1,0.05214081837700307,destabilizing
+RBFOX1,MLLT3,0.17836792421315528,destabilizing
+RBFOX1,FMN1,0.0625545728116648,destabilizing
+RBFOX1,ADGRB3,0.08762518884831798,destabilizing
+RBFOX1,ROBO1,0.14877378073953718,destabilizing
+RBFOX1,SYPL1,0.08629682685512384,destabilizing
+RBFOX1,PTPRD,0.1298569728812735,destabilizing
+RBFOX1,FAM155A,0.13198160208236454,destabilizing
+RBFOX1,LARP1B,0.1129347535699814,destabilizing
+RBFOX2,TRERF1,0.27777567622123667,destabilizing
+RBFOX2,SORCS1,0.19049617133716062,destabilizing
+RBFOX2,NCOA1,0.10854528379041228,destabilizing
+RBFOX2,COPA,0.09570899595138288,destabilizing
+RBFOX2,FCHSD2,0.14392749007697647,destabilizing
+RBFOX2,PDE3A,0.3400240380645849,destabilizing
+RBFOX2,UNC79,0.2787087990855528,destabilizing
+RBFOX2,DOC2B,0.19043056671449848,destabilizing
+RBFOX2,TMTC2,0.25429604369434017,destabilizing
+RBFOX2,KALRN,0.21268011507585033,destabilizing
+RBFOX2,CHD1,0.16325857315056622,destabilizing
+RBFOX2,PAK3,0.08290036736853552,destabilizing
+RBFOX2,UBE2E2,0.08818723231630975,destabilizing
+RBFOX2,PPARD,0.1302739429453702,destabilizing
+RBFOX2,BRAF,0.09741139772500433,destabilizing
+RBFOX2,RYR2,0.18844145129322615,destabilizing
+RBFOX2,ZNF609,0.0678151207279505,destabilizing
+RBFOX2,MTMR7,0.2737020766040237,destabilizing
+RBFOX2,EIF4E,0.2500294328387943,destabilizing
+RBFOX2,SOX11,0.12170219079060181,destabilizing
+RBFOX2,EPB41L4B,0.20453637147052353,destabilizing
+RBFOX2,CACNA1B,0.1902128537539764,destabilizing
+RBFOX2,TBC1D5,0.12655536919508845,destabilizing
+RBFOX2,LRRTM4,0.2131381951348992,destabilizing
+RBFOX2,SIRPA,0.2377708966156641,destabilizing
+RBFOX2,PTEN,0.169891066252915,destabilizing
+RBFOX2,SPPL3,0.07404752673321997,destabilizing
+RBFOX2,FRY,0.2769635438027201,destabilizing
+RBFOX2,MACROD2,0.2441337503191596,destabilizing
+RBFOX2,FOXN3,0.08730348459271747,destabilizing
+RBFOX2,SHANK2,0.31088669512802986,destabilizing
+RBFOX2,CDK12,0.3512565523899636,destabilizing
+RBFOX2,RFX7,0.24521214586990714,destabilizing
+RBFOX2,UBR5,0.14381701771029917,destabilizing
+RBFOX2,JARID2,0.1364273928802983,destabilizing
+RBFOX2,MPHOSPH8,0.19399039248397262,destabilizing
+RBFOX2,DIP2C,0.21103709234722048,destabilizing
+RBFOX2,ZNF423,0.11026094224784264,destabilizing
+RBFOX2,UBR3,0.1992269454123861,destabilizing
+RBFOX2,MGAT5,0.13562966229498677,destabilizing
+RBFOX2,DLG2,0.17496982712413803,destabilizing
+RBFOX2,CHST12,0.35805603868981273,destabilizing
+RBFOX2,EML5,0.30466553933113005,destabilizing
+RBFOX2,CENPP,0.1640453756248996,destabilizing
+RBFOX2,PSME4,0.257956447460655,destabilizing
+RBFOX2,TMEM106B,0.3152307301997853,destabilizing
+RBFOX2,EPHA5,0.21675589561327954,destabilizing
+RBFOX2,KCNB2,0.23591639804720937,destabilizing
+RBFOX2,ZNF83,0.18265495661113323,destabilizing
+RBFOX2,SOX6,0.13370183619896575,destabilizing
+RBFOX2,ZNF521,0.21695465044098547,destabilizing
+RBFOX2,PLEKHA5,0.18171613225416072,destabilizing
+RBFOX2,DTL,0.20009212809345986,destabilizing
+RBFOX2,NOVA1,0.29628729574730656,destabilizing
+RBFOX2,CCNY,0.2617817145520887,destabilizing
+RBFOX2,ARIH1,0.18708239060532297,destabilizing
+RBFOX2,FAM171B,0.08231347970012501,destabilizing
+RBFOX2,EPB41L5,0.1741739159988619,destabilizing
+RBFOX2,GPR158,0.26710008182354733,destabilizing
+RBFOX2,NCOA2,0.21398489743338,destabilizing
+RBFOX2,PRKCB,0.0702441314810384,destabilizing
+RBFOX2,PUM2,0.05252236656971002,destabilizing
+RBFOX2,MARCKS,0.06968162982340552,destabilizing
+RBFOX2,ALK,0.16270777184729568,destabilizing
+RBFOX2,ACACA,0.1376660012277437,destabilizing
+RBFOX2,ARHGAP26,0.07095057576173532,destabilizing
+RBFOX2,CTNND2,0.12749867412971216,destabilizing
+RBFOX2,IFT172,0.23199898299925947,destabilizing
+RBFOX2,CCNT1,0.14955148651425443,destabilizing
+RBFOX2,ENAH,0.06613703510359992,destabilizing
+RBFOX2,DTWD2,0.2616167605371735,destabilizing
+RBFOX2,SIK3,0.13435712216122078,destabilizing
+RBFOX2,CPEB3,0.25351533604954385,destabilizing
+RBFOX2,CADM2,0.14547695652815817,destabilizing
+RBFOX2,XKR6,0.28398966232715783,destabilizing
+RBFOX2,RMND5A,0.07602544035585729,destabilizing
+RBFOX2,CADPS,0.12315355373703378,destabilizing
+RBFOX2,FGF13,0.08013076338109465,destabilizing
+RBFOX2,TCF20,0.2699902846339232,destabilizing
+RBFOX2,CDKAL1,0.14015091405646818,destabilizing
+RBFOX2,DGKI,0.193921193902489,destabilizing
+RBFOX2,EXOC6B,0.30169190091100023,destabilizing
+RBFOX2,MAGI3,0.22805790894632288,destabilizing
+RBFOX2,SBF2,0.15022163075909056,destabilizing
+RBFOX2,INPP4B,0.24865999905399908,destabilizing
+RBFOX2,ERC1,0.10388486153123307,destabilizing
+RBFOX2,PTPRS,0.3125105973535394,destabilizing
+RBFOX2,CBFA2T2,0.1328876206730821,destabilizing
+RBFOX2,SPDYE3,0.2584913242532052,destabilizing
+RBFOX2,TMEM178B,0.12748284094788814,destabilizing
+RBFOX2,KMT2C,0.0729319018011364,destabilizing
+RBFOX2,CACNA2D1,0.07433798779662418,destabilizing
+RBFOX2,DMD,0.3852467168347535,destabilizing
+RBFOX2,EIF4G3,0.05939978032511579,destabilizing
+RBFOX2,MCU,0.18413611095297946,destabilizing
+RBFOX2,SSH2,0.18914092662572132,destabilizing
+RBFOX2,TCF12,0.06350545969366334,destabilizing
+RBFOX2,DOCK3,0.27688668799737143,destabilizing
+RBFOX2,HS6ST3,0.2859844484529399,destabilizing
+RBFOX2,LPP,0.33562689279821717,destabilizing
+RBFOX2,STAG1,0.20690095560421554,destabilizing
+RBFOX2,CAPZA2,0.22487460822550207,destabilizing
+RBFOX2,ADGRL3,0.1384283061853399,destabilizing
+RBFOX2,PHACTR1,0.07658264579322319,destabilizing
+RBFOX2,UBE2R2,0.27152754855019295,destabilizing
+RBFOX2,GTF2IRD1,0.25025575994734495,destabilizing
+RBFOX2,CCBE1,0.1607440227758107,destabilizing
+RBFOX2,FTX,0.09870641475872133,destabilizing
+RBFOX2,JMJD1C,0.07112274810589721,destabilizing
+RBFOX2,TTC28,0.16201143735920198,destabilizing
+RBFOX2,SBNO1,0.15543656827980065,destabilizing
+RBFOX2,RIMS2,0.1307630693339769,destabilizing
+RBFOX2,IGF1R,0.12097253574372795,destabilizing
+RBFOX2,TRIO,0.15582754123269416,destabilizing
+RBFOX2,KCND2,0.10105963153761952,destabilizing
+RBFOX2,BTBD9,0.262582140100626,destabilizing
+RBFOX2,CNGB1,0.2940785736876868,destabilizing
+RBFOX2,FMN2,0.22410810294006853,destabilizing
+RBFOX2,ENSG00000228222,0.3656719907689072,destabilizing
+RBFOX2,ATXN1,0.08251480236946378,destabilizing
+RBFOX2,PRKN,0.35676398630722383,destabilizing
+RBFOX2,RASA2,0.23338065486914672,destabilizing
+RBFOX2,PPP1R12B,0.14450178574041914,destabilizing
+RBFOX2,FRMD4A,0.20093870777823494,destabilizing
+RBFOX2,CAMK1D,0.10865251982270167,destabilizing
+RBFOX2,PARD3,0.0964065508892039,destabilizing
+RBFOX2,SEMA6D,0.20357587895597762,destabilizing
+RBFOX2,WIPF2,0.2303379571448004,destabilizing
+RBFOX2,DLEU1,0.32092033818532334,destabilizing
+RBFOX2,TSHZ2,0.13437413782286758,destabilizing
+RBFOX2,MED13L,0.154567838724971,destabilizing
+RBFOX2,AFF3,0.09092103488157001,destabilizing
+RBFOX2,KAZN,0.1953701349449864,destabilizing
+RBFOX2,KANSL1,0.13745504738026443,destabilizing
+RBFOX2,FRMD5,0.20209026386305892,destabilizing
+RBFOX2,LINC00174,0.23902349883579974,destabilizing
+RBFOX2,PPM1E,0.2490594432058761,destabilizing
+RBFOX2,ARL3,0.12737850441401552,destabilizing
+RBFOX2,MBD5,0.1996293768924172,destabilizing
+RBFOX2,ELAVL3,0.220933056651702,destabilizing
+RBFOX2,SLIT2,0.337040446655647,destabilizing
+RBFOX2,CLASP1,0.1472149089012007,destabilizing
+RBFOX2,DOCK4,0.0881272224025218,destabilizing
+RBFOX2,UNC5C,0.23244446055348125,destabilizing
+RBFOX2,CACNA2D3,-0.1267874401835708,stabilizing
+RBFOX2,RC3H1,0.1846319437944914,destabilizing
+RBFOX2,NEGR1,0.21099303478290612,destabilizing
+RBFOX2,ENOX1,0.36699168392851506,destabilizing
+RBFOX2,SCUBE1,0.1872651109035167,destabilizing
+RBFOX2,GPHN,0.17750773614133847,destabilizing
+RBFOX2,NAV3,0.296321060360184,destabilizing
+RBFOX2,EBF1,0.09815754372108222,destabilizing
+RBFOX2,TOMM22,0.28564616915109264,destabilizing
+RBFOX2,MBNL2,0.09251193786283088,destabilizing
+RBFOX2,ANKFN1,0.08994565810565122,destabilizing
+RBFOX2,MAGI2,0.13941080101234707,destabilizing
+RBFOX2,LSAMP,0.17927582910699788,destabilizing
+RBFOX2,AKAP6,0.2277651854000528,destabilizing
+RBFOX2,TMED2,0.15413185104576357,destabilizing
+RBFOX2,ZBTB20,0.2037653260058644,destabilizing
+RBFOX2,GRIK2,0.2238178096823621,destabilizing
+RBFOX2,SOX5,0.17636852194946243,destabilizing
+RBFOX2,LRRC37A3,0.3206538421809958,destabilizing
+RBFOX2,TMEM132C,0.09613371681996553,destabilizing
+RBFOX2,EYS,0.16854890510639028,destabilizing
+RBFOX2,ARID1B,0.1674435980567761,destabilizing
+RBFOX2,PRKCE,0.18610916903029412,destabilizing
+RBFOX2,RBFOX1,-0.15934786638162907,stabilizing
+RBFOX2,SDK1,0.11490554194594339,destabilizing
+RBFOX2,NRG1,0.10299027457423439,destabilizing
+RBFOX2,MLLT3,0.30359437746889445,destabilizing
+RBFOX2,AUTS2,0.07244010323289031,destabilizing
+RBFOX2,FMN1,0.12991282115036898,destabilizing
+RBFOX2,ADGRB3,0.1701142224783839,destabilizing
+RBFOX2,ROBO1,0.2529021914199527,destabilizing
+RBFOX2,SYPL1,0.14518944599965034,destabilizing
+RBFOX2,PTPRD,0.19897090651567678,destabilizing
+RBFOX2,FAM155A,0.2669038410120564,destabilizing
+RBFOX2,LARP1B,0.2365101792558233,destabilizing
+RBM3,TRERF1,0.15000927518835802,destabilizing
+RBM3,SORCS1,0.10199820368806956,destabilizing
+RBM3,COPA,0.05788765180103066,destabilizing
+RBM3,PDE3A,0.13341637530309985,destabilizing
+RBM3,UNC79,0.1591227033422507,destabilizing
+RBM3,DOC2B,0.08748730569401139,destabilizing
+RBM3,TMTC2,0.1614854813136012,destabilizing
+RBM3,KALRN,0.08650840764715859,destabilizing
+RBM3,CHD1,0.09746528947684345,destabilizing
+RBM3,PAK3,0.055556777041451,destabilizing
+RBM3,PPARD,0.0904882723025267,destabilizing
+RBM3,RYR2,0.14723729861073706,destabilizing
+RBM3,MTMR7,0.15174733242589178,destabilizing
+RBM3,EIF4E,0.1368199523464089,destabilizing
+RBM3,EPB41L4B,0.08986086792504747,destabilizing
+RBM3,CACNA1B,0.10083569186377028,destabilizing
+RBM3,TBC1D5,0.0627648147461829,destabilizing
+RBM3,LRRTM4,0.12001604013704326,destabilizing
+RBM3,SIRPA,0.13208816427728232,destabilizing
+RBM3,PTEN,0.11404176182424813,destabilizing
+RBM3,FRY,0.16422038914522283,destabilizing
+RBM3,MACROD2,0.12190479992727,destabilizing
+RBM3,FOXN3,0.062492303943586486,destabilizing
+RBM3,SHANK2,0.19871454496491261,destabilizing
+RBM3,CDK12,0.15286904834163093,destabilizing
+RBM3,RFX7,0.1259870130266566,destabilizing
+RBM3,UBR5,0.07172937251866354,destabilizing
+RBM3,JARID2,0.08174372666521605,destabilizing
+RBM3,MPHOSPH8,0.11354924990034727,destabilizing
+RBM3,DIP2C,0.0959496482796831,destabilizing
+RBM3,ZNF423,0.060818359839965294,destabilizing
+RBM3,UBR3,0.13040205185856002,destabilizing
+RBM3,MGAT5,0.06419149358684477,destabilizing
+RBM3,DLG2,0.08128009838612169,destabilizing
+RBM3,CHST12,0.20179731062748263,destabilizing
+RBM3,EML5,0.16836068236527119,destabilizing
+RBM3,PSME4,0.14939676483387843,destabilizing
+RBM3,TMEM106B,0.14853410049237079,destabilizing
+RBM3,EPHA5,0.11429570121567294,destabilizing
+RBM3,KCNB2,0.14544382057702623,destabilizing
+RBM3,ZNF83,0.10359947668080745,destabilizing
+RBM3,SOX6,0.07031427892468464,destabilizing
+RBM3,ZNF521,0.11196337737184463,destabilizing
+RBM3,PLEKHA5,0.10371618569068829,destabilizing
+RBM3,DTL,0.08951684517990811,destabilizing
+RBM3,NOVA1,0.14790644913366605,destabilizing
+RBM3,CCNY,0.12565144714415796,destabilizing
+RBM3,ARIH1,0.11984677882156856,destabilizing
+RBM3,EPB41L5,0.10287211881188982,destabilizing
+RBM3,GPR158,0.1595277850944963,destabilizing
+RBM3,NCOA2,0.10662428369796209,destabilizing
+RBM3,ALK,0.13903851983004362,destabilizing
+RBM3,IFT172,0.13693278937237616,destabilizing
+RBM3,CCNT1,0.08214465842374188,destabilizing
+RBM3,SIK3,0.10870603467632568,destabilizing
+RBM3,CPEB3,0.12663433506601562,destabilizing
+RBM3,CADM2,0.05753236780820878,destabilizing
+RBM3,XKR6,0.14181706898094976,destabilizing
+RBM3,CADPS,0.08494095208769138,destabilizing
+RBM3,TCF20,0.14854145421613252,destabilizing
+RBM3,CDKAL1,0.09459763019901535,destabilizing
+RBM3,DGKI,0.10909270254403595,destabilizing
+RBM3,EXOC6B,0.16403061846035388,destabilizing
+RBM3,MAGI3,0.1271356991326084,destabilizing
+RBM3,SBF2,0.0740932477516465,destabilizing
+RBM3,INPP4B,0.12150737308425405,destabilizing
+RBM3,ERC1,0.06568454860119195,destabilizing
+RBM3,PTPRS,0.1521958656239183,destabilizing
+RBM3,CBFA2T2,0.061925439975523,destabilizing
+RBM3,SPDYE3,0.1050468950356668,destabilizing
+RBM3,TMEM178B,0.06447066735905116,destabilizing
+RBM3,DMD,0.2015784374176003,destabilizing
+RBM3,EIF4G3,0.057103495676059005,destabilizing
+RBM3,MCU,0.13694513955541443,destabilizing
+RBM3,SSH2,0.10867425580528102,destabilizing
+RBM3,DOCK3,0.133349159508234,destabilizing
+RBM3,HS6ST3,0.13933418047702453,destabilizing
+RBM3,LPP,0.12457344125348431,destabilizing
+RBM3,STAG1,0.1079771146892362,destabilizing
+RBM3,CAPZA2,0.10098569433999019,destabilizing
+RBM3,UBE2R2,0.13987488477597954,destabilizing
+RBM3,GTF2IRD1,0.1397076476816284,destabilizing
+RBM3,CCBE1,0.07898186687870602,destabilizing
+RBM3,SBNO1,0.08156117938686552,destabilizing
+RBM3,RIMS2,0.07943971081286388,destabilizing
+RBM3,IGF1R,0.055187029513295106,destabilizing
+RBM3,TRIO,0.0631666227155536,destabilizing
+RBM3,BTBD9,0.12997446707098026,destabilizing
+RBM3,CNGB1,0.15566043629805984,destabilizing
+RBM3,FMN2,0.11639189439067515,destabilizing
+RBM3,ENSG00000228222,0.19052836093570746,destabilizing
+RBM3,ATXN1,0.06219249236796218,destabilizing
+RBM3,PRKN,0.17407929001412936,destabilizing
+RBM3,RASA2,0.09651446521662219,destabilizing
+RBM3,PPP1R12B,0.09152985346864315,destabilizing
+RBM3,FRMD4A,0.10680438481192571,destabilizing
+RBM3,CAMK1D,0.06897221485646308,destabilizing
+RBM3,PARD3,0.055689511472648966,destabilizing
+RBM3,SEMA6D,0.12357619785221585,destabilizing
+RBM3,WIPF2,0.12203329010761567,destabilizing
+RBM3,DLEU1,0.17755897466683462,destabilizing
+RBM3,TSHZ2,0.07937809398748784,destabilizing
+RBM3,MED13L,0.08760550197678604,destabilizing
+RBM3,AFF3,0.055202006060517235,destabilizing
+RBM3,KAZN,0.1193789914157981,destabilizing
+RBM3,FRMD5,0.10683918823504227,destabilizing
+RBM3,LINC00174,0.1127740583407144,destabilizing
+RBM3,PPM1E,0.11878230075254079,destabilizing
+RBM3,ARL3,0.07790506428012538,destabilizing
+RBM3,MBD5,0.11188165920107547,destabilizing
+RBM3,ELAVL3,0.10071612462004591,destabilizing
+RBM3,SLIT2,0.14904518118081123,destabilizing
+RBM3,CLASP1,0.07439468086838098,destabilizing
+RBM3,DOCK4,0.05348601710954862,destabilizing
+RBM3,UNC5C,0.114561526842568,destabilizing
+RBM3,RC3H1,0.09083091346100931,destabilizing
+RBM3,NEGR1,0.13264803054114865,destabilizing
+RBM3,ENOX1,0.20934337571728007,destabilizing
+RBM3,SCUBE1,0.11294584446203063,destabilizing
+RBM3,GPHN,0.11876447164966789,destabilizing
+RBM3,NAV3,0.13788494554185957,destabilizing
+RBM3,EBF1,0.0820456813308908,destabilizing
+RBM3,TOMM22,0.15465409396971436,destabilizing
+RBM3,MBNL2,0.06115315100053345,destabilizing
+RBM3,MAGI2,0.06886039071877369,destabilizing
+RBM3,LSAMP,0.07970586942691461,destabilizing
+RBM3,AKAP6,0.1319469690135359,destabilizing
+RBM3,TMED2,0.09530776062740369,destabilizing
+RBM3,ZBTB20,0.10238881964147312,destabilizing
+RBM3,GRIK2,0.12435039250780029,destabilizing
+RBM3,SOX5,0.09064293759238097,destabilizing
+RBM3,LRRC37A3,0.15117246032275197,destabilizing
+RBM3,EYS,0.06924160688724733,destabilizing
+RBM3,ARID1B,0.07391648908659838,destabilizing
+RBM3,PRKCE,0.08190066476129597,destabilizing
+RBM3,SDK1,0.07779953533604869,destabilizing
+RBM3,MLLT3,0.18304802857018992,destabilizing
+RBM3,AUTS2,0.052826091927951645,destabilizing
+RBM3,FMN1,0.07300788716896953,destabilizing
+RBM3,ADGRB3,0.09398216490141034,destabilizing
+RBM3,ROBO1,0.11280685567452424,destabilizing
+RBM3,SYPL1,0.08604558376891847,destabilizing
+RBM3,PTPRD,0.11598192529949566,destabilizing
+RBM3,FAM155A,0.12791477851316116,destabilizing
+RBM3,LARP1B,0.12175011216076108,destabilizing
+RBM5,TRERF1,0.08254687889383652,destabilizing
+RBM5,PDE3A,0.10527846721656026,destabilizing
+RBM5,UNC79,0.0832380632558118,destabilizing
+RBM5,DOC2B,0.06860421012008448,destabilizing
+RBM5,TMTC2,0.07911492837022537,destabilizing
+RBM5,KALRN,0.07934512916841234,destabilizing
+RBM5,MTMR7,0.09819092331434971,destabilizing
+RBM5,CACNA1B,0.06087940721053755,destabilizing
+RBM5,FRY,0.09948903348495623,destabilizing
+RBM5,MACROD2,0.07043346100430999,destabilizing
+RBM5,CDK12,0.12988628890541498,destabilizing
+RBM5,CHST12,0.14494656053804367,destabilizing
+RBM5,TMEM106B,0.07938786165473141,destabilizing
+RBM5,EPB41L5,0.059760843675173196,destabilizing
+RBM5,NCOA2,0.07803926485313345,destabilizing
+RBM5,ALK,0.10895417775333169,destabilizing
+RBM5,IFT172,0.08197753660487667,destabilizing
+RBM5,XKR6,0.09218338036563314,destabilizing
+RBM5,DGKI,0.067476662529835,destabilizing
+RBM5,MAGI3,0.07904259225603653,destabilizing
+RBM5,DMD,0.1106594818917885,destabilizing
+RBM5,DOCK3,0.07809869232926987,destabilizing
+RBM5,CAPZA2,0.07093845971696479,destabilizing
+RBM5,RASA2,0.07523955747335025,destabilizing
+RBM5,SEMA6D,0.06521658986158807,destabilizing
+RBM5,WIPF2,0.07515494954291285,destabilizing
+RBM5,FRMD5,0.0631154312560575,destabilizing
+RBM5,LINC00174,0.07048112257895121,destabilizing
+RBM5,MBD5,0.05934249051273602,destabilizing
+RBM5,ELAVL3,0.06964495284408054,destabilizing
+RBM5,SLIT2,0.08927243193934342,destabilizing
+RBM5,UNC5C,0.07429611830929489,destabilizing
+RBM5,ENOX1,0.12447141829404518,destabilizing
+RBM5,NAV3,0.08533148120318611,destabilizing
+RBM5,TOMM22,0.08816366990874305,destabilizing
+RBM5,GRIK2,0.06176244227680714,destabilizing
+RBM5,SOX5,0.07361423304534603,destabilizing
+RBM5,LRRC37A3,0.11649182917562326,destabilizing
+RBM5,MLLT3,0.12635071504080486,destabilizing
+RBM5,PTPRD,0.06027235212345913,destabilizing
+RBM10,DOC2B,0.06052084428708951,destabilizing
+RBM10,TMTC2,0.09479117214036606,destabilizing
+RBM10,KALRN,0.07051665230445801,destabilizing
+RBM10,CHD1,0.06299905186860397,destabilizing
+RBM10,MTMR7,0.09091894744154211,destabilizing
+RBM10,EIF4E,0.11576231597040063,destabilizing
+RBM10,FRY,0.09708953951873997,destabilizing
+RBM10,RUNX1T1,0.05726934363636364,destabilizing
+RBM10,MACROD2,0.07646385470506022,destabilizing
+RBM10,MPHOSPH8,0.06990983024728654,destabilizing
+RBM10,EML5,0.10762968976833456,destabilizing
+RBM10,CENPP,0.16516032515129375,destabilizing
+RBM10,TMEM106B,0.08607082032476791,destabilizing
+RBM10,NOVA1,0.10139908255478144,destabilizing
+RBM10,EPB41L5,0.06222353784814414,destabilizing
+RBM10,ALK,0.13787937969827094,destabilizing
+RBM10,IFT172,0.07043597702098697,destabilizing
+RBM10,CCNT1,0.06298733897077902,destabilizing
+RBM10,CADM2,0.05779099393474306,destabilizing
+RBM10,XKR6,0.0850640724631702,destabilizing
+RBM10,MAGI3,0.0733373230574037,destabilizing
+RBM10,DMD,0.07534826000705362,destabilizing
+RBM10,DOCK3,0.09998649753467807,destabilizing
+RBM10,LPP,0.09407448210400633,destabilizing
+RBM10,STAG1,0.06912387054484852,destabilizing
+RBM10,CAPZA2,0.07671045468510275,destabilizing
+RBM10,GTF2IRD1,0.05771141806843754,destabilizing
+RBM10,ENSG00000228222,0.12200969241017173,destabilizing
+RBM10,RASA2,0.07731179188996368,destabilizing
+RBM10,WIPF2,0.08565570825908106,destabilizing
+RBM10,DLEU1,0.11496911790155045,destabilizing
+RBM10,FRMD5,0.06823484504076119,destabilizing
+RBM10,LINC00174,0.08217332843805573,destabilizing
+RBM10,ELAVL3,0.06234354948560465,destabilizing
+RBM10,UNC5C,0.07922307433722688,destabilizing
+RBM10,GRIK2,0.05985019180885013,destabilizing
+RBM10,LRRC37A3,0.10576598904410502,destabilizing
+RBM10,MLLT3,0.10691115761712384,destabilizing
+RBM10,PTPRD,0.07331855174872945,destabilizing
+RBM25,TRERF1,0.1336313572842409,destabilizing
+RBM25,SORCS1,0.09622614655877788,destabilizing
+RBM25,PDE3A,0.11494217669714633,destabilizing
+RBM25,UNC79,0.15504404610097922,destabilizing
+RBM25,DOC2B,0.10879436666391697,destabilizing
+RBM25,TMTC2,0.10881807400221,destabilizing
+RBM25,KALRN,0.0822851246906055,destabilizing
+RBM25,CHD1,0.08261385377784344,destabilizing
+RBM25,PPARD,0.07612909501986947,destabilizing
+RBM25,RYR2,0.10421701636938657,destabilizing
+RBM25,MTMR7,0.1083082064589277,destabilizing
+RBM25,EIF4E,0.10344709894905368,destabilizing
+RBM25,EPB41L4B,0.08511650277215739,destabilizing
+RBM25,CACNA1B,0.08171168133960242,destabilizing
+RBM25,LRRTM4,0.0838833137977742,destabilizing
+RBM25,FRY,0.13431626521933304,destabilizing
+RBM25,MACROD2,0.10147028845033224,destabilizing
+RBM25,SHANK2,0.15336511742461365,destabilizing
+RBM25,CDK12,0.16945281982164412,destabilizing
+RBM25,RFX7,0.11083669917517788,destabilizing
+RBM25,JARID2,0.05880706938413621,destabilizing
+RBM25,MPHOSPH8,0.11003958767000355,destabilizing
+RBM25,DIP2C,0.07086614525302379,destabilizing
+RBM25,UBR3,0.09155612684774683,destabilizing
+RBM25,DLG2,0.0801786360288054,destabilizing
+RBM25,CHST12,0.20143804193936182,destabilizing
+RBM25,EML5,0.12748085549973806,destabilizing
+RBM25,CENPP,0.15732562300610292,destabilizing
+RBM25,PSME4,0.12371337527173269,destabilizing
+RBM25,TMEM106B,0.09860859024135854,destabilizing
+RBM25,EPHA5,0.09038313593701781,destabilizing
+RBM25,KCNB2,0.1498015530434976,destabilizing
+RBM25,ZNF83,0.06700417785080738,destabilizing
+RBM25,SOX6,0.06992995560159485,destabilizing
+RBM25,ZNF521,0.09419306386257405,destabilizing
+RBM25,PLEKHA5,0.059933110041538826,destabilizing
+RBM25,NOVA1,0.12312320128956138,destabilizing
+RBM25,CCNY,0.1473403802497396,destabilizing
+RBM25,ARIH1,0.08186813792370763,destabilizing
+RBM25,EPB41L5,0.07508924277499485,destabilizing
+RBM25,GPR158,0.09417812650010143,destabilizing
+RBM25,NCOA2,0.08057007445847128,destabilizing
+RBM25,ALK,0.14572483623506427,destabilizing
+RBM25,IFT172,0.11560668274318411,destabilizing
+RBM25,CCNT1,0.0748412282053983,destabilizing
+RBM25,DTWD2,0.1655153935795376,destabilizing
+RBM25,SIK3,0.09519891563148984,destabilizing
+RBM25,CPEB3,0.1133383691156439,destabilizing
+RBM25,XKR6,0.13094418650646505,destabilizing
+RBM25,TCF20,0.11478422709392144,destabilizing
+RBM25,DGKI,0.1111641145307555,destabilizing
+RBM25,EXOC6B,0.14671399505809535,destabilizing
+RBM25,MAGI3,0.13355128349018133,destabilizing
+RBM25,SBF2,0.058728821021703834,destabilizing
+RBM25,INPP4B,0.08765514325775275,destabilizing
+RBM25,PTPRS,0.1280751948349715,destabilizing
+RBM25,SPDYE3,0.07175279343788946,destabilizing
+RBM25,DMD,0.1786580436157926,destabilizing
+RBM25,MCU,0.07044875377556507,destabilizing
+RBM25,SSH2,0.08261246368082727,destabilizing
+RBM25,DOCK3,0.13576393610287005,destabilizing
+RBM25,HS6ST3,0.112955091963018,destabilizing
+RBM25,LPP,0.0971860463324057,destabilizing
+RBM25,STAG1,0.08895130199802713,destabilizing
+RBM25,CAPZA2,0.12157090416270383,destabilizing
+RBM25,PHACTR1,0.06387263216006024,destabilizing
+RBM25,UBE2R2,0.11604506951575902,destabilizing
+RBM25,GTF2IRD1,0.0936878050935419,destabilizing
+RBM25,TTC28,0.07894410585558617,destabilizing
+RBM25,SBNO1,0.07610940141078179,destabilizing
+RBM25,BTBD9,0.12031722051541144,destabilizing
+RBM25,CNGB1,0.14376043239056432,destabilizing
+RBM25,ENSG00000228222,0.18177403690749822,destabilizing
+RBM25,PRKN,0.17621448274370266,destabilizing
+RBM25,RASA2,0.10559209120072653,destabilizing
+RBM25,FRMD4A,0.09956967139916187,destabilizing
+RBM25,SEMA6D,0.0717792424057004,destabilizing
+RBM25,WIPF2,0.1166608181366104,destabilizing
+RBM25,DLEU1,0.12722248557602622,destabilizing
+RBM25,TSHZ2,0.08335497041689406,destabilizing
+RBM25,MED13L,0.07959078655695158,destabilizing
+RBM25,KANSL1,0.0763366442338564,destabilizing
+RBM25,FRMD5,0.11858980968917848,destabilizing
+RBM25,LINC00174,0.09866027438190847,destabilizing
+RBM25,PPM1E,0.10055519813366506,destabilizing
+RBM25,ARL3,0.09130273160347903,destabilizing
+RBM25,MBD5,0.07343394605660236,destabilizing
+RBM25,ELAVL3,0.11364503532428846,destabilizing
+RBM25,SLIT2,0.11517574650187173,destabilizing
+RBM25,CLASP1,0.08149987568015499,destabilizing
+RBM25,UNC5C,0.1226779691109479,destabilizing
+RBM25,RC3H1,0.05951805687282728,destabilizing
+RBM25,NEGR1,0.11282242109148034,destabilizing
+RBM25,ENOX1,0.16923532646028538,destabilizing
+RBM25,SCUBE1,0.08486256373337628,destabilizing
+RBM25,GPHN,0.10080367743223193,destabilizing
+RBM25,NAV3,0.12431998732501015,destabilizing
+RBM25,TOMM22,0.1127132729374094,destabilizing
+RBM25,ANKFN1,0.05526241390830434,destabilizing
+RBM25,MAGI2,0.0676220313850716,destabilizing
+RBM25,LSAMP,0.057424957349592486,destabilizing
+RBM25,AKAP6,0.10960094930410784,destabilizing
+RBM25,TMED2,0.0883290081054703,destabilizing
+RBM25,ZBTB20,0.10266433059876172,destabilizing
+RBM25,GRIK2,0.10202658308889438,destabilizing
+RBM25,LRRC37A3,0.16750040525103005,destabilizing
+RBM25,EYS,0.08474375467048062,destabilizing
+RBM25,ARID1B,0.08152902984741336,destabilizing
+RBM25,PRKCE,0.06779182512046032,destabilizing
+RBM25,RBFOX1,-0.07336757998942722,stabilizing
+RBM25,MLLT3,0.1866306070221314,destabilizing
+RBM25,FMN1,0.057447764303954145,destabilizing
+RBM25,ROBO1,0.10104911151718844,destabilizing
+RBM25,PTPRD,0.08447776598715571,destabilizing
+RBM25,FAM155A,0.11686677759901154,destabilizing
+RBM25,LARP1B,0.10601438638344143,destabilizing
+RBM39,TRERF1,0.1964710296689071,destabilizing
+RBM39,SORCS1,0.1461580620682043,destabilizing
+RBM39,FCHSD2,0.10590138256820496,destabilizing
+RBM39,PDE3A,0.23730541361232793,destabilizing
+RBM39,UNC79,0.23125508650417542,destabilizing
+RBM39,DOC2B,0.14115852849834687,destabilizing
+RBM39,TMTC2,0.2059483764151876,destabilizing
+RBM39,KALRN,0.13116727335524622,destabilizing
+RBM39,CHD1,0.09633538898125758,destabilizing
+RBM39,PAK3,0.061428748361574,destabilizing
+RBM39,UBE2E2,0.10992240172095515,destabilizing
+RBM39,PPARD,0.14137135150825544,destabilizing
+RBM39,TOX,0.08468540427966598,destabilizing
+RBM39,RYR2,0.19503361655743778,destabilizing
+RBM39,MTMR7,0.19437928329786,destabilizing
+RBM39,EIF4E,0.2133704682755893,destabilizing
+RBM39,SOX11,0.09084991625405281,destabilizing
+RBM39,EPB41L4B,0.13056772012432658,destabilizing
+RBM39,CACNA1B,0.1398427397368596,destabilizing
+RBM39,TBC1D5,0.08901660651727578,destabilizing
+RBM39,LRRTM4,0.15450310152818947,destabilizing
+RBM39,SIRPA,0.1897774239340587,destabilizing
+RBM39,PTEN,0.1466626547945346,destabilizing
+RBM39,FRY,0.2018644991647858,destabilizing
+RBM39,MACROD2,0.17852478367344168,destabilizing
+RBM39,FOXN3,0.059692381571208646,destabilizing
+RBM39,SHANK2,0.2554159025530829,destabilizing
+RBM39,CDK12,0.2720647102731622,destabilizing
+RBM39,RFX7,0.20208495582893607,destabilizing
+RBM39,UBR5,0.09621171101068662,destabilizing
+RBM39,JARID2,0.08888993287302828,destabilizing
+RBM39,MPHOSPH8,0.15208107680645983,destabilizing
+RBM39,DIP2C,0.128579249236514,destabilizing
+RBM39,ZNF423,0.07852296646963453,destabilizing
+RBM39,UBR3,0.12430275552155058,destabilizing
+RBM39,MGAT5,0.08592322602525235,destabilizing
+RBM39,DLG2,0.13625113348255596,destabilizing
+RBM39,CHST12,0.2896038372874915,destabilizing
+RBM39,EML5,0.19194615268350249,destabilizing
+RBM39,CENPP,0.22583387274811004,destabilizing
+RBM39,PSME4,0.22052149010720645,destabilizing
+RBM39,TMEM106B,0.23056519104188308,destabilizing
+RBM39,EPHA5,0.1658649812338,destabilizing
+RBM39,KCNB2,0.20667065954526742,destabilizing
+RBM39,ZNF83,0.14782345897999652,destabilizing
+RBM39,SOX6,0.11137443777285666,destabilizing
+RBM39,ZNF521,0.17506259733326254,destabilizing
+RBM39,PLEKHA5,0.10341210615518343,destabilizing
+RBM39,NOVA1,0.22839389445874536,destabilizing
+RBM39,CCNY,0.19220926307199515,destabilizing
+RBM39,ARIH1,0.14385818278960394,destabilizing
+RBM39,EPB41L5,0.1244053973987491,destabilizing
+RBM39,GPR158,0.19323107192580372,destabilizing
+RBM39,NCOA2,0.15272786971031221,destabilizing
+RBM39,ALK,0.1784603724242128,destabilizing
+RBM39,ACACA,0.08871894605468143,destabilizing
+RBM39,CTNND2,0.059700022617935763,destabilizing
+RBM39,IFT172,0.17749456087336588,destabilizing
+RBM39,CCNT1,0.111724156387822,destabilizing
+RBM39,DTWD2,0.22470555534998055,destabilizing
+RBM39,SIK3,0.1660485352974539,destabilizing
+RBM39,CPEB3,0.21472996656079066,destabilizing
+RBM39,CADM2,0.07084229555207769,destabilizing
+RBM39,XKR6,0.2206811145380342,destabilizing
+RBM39,RMND5A,0.06407760158308617,destabilizing
+RBM39,CADPS,0.0960712115203777,destabilizing
+RBM39,TCF20,0.2010377533774998,destabilizing
+RBM39,CDKAL1,0.09037429410011294,destabilizing
+RBM39,DGKI,0.13774353604950848,destabilizing
+RBM39,EXOC6B,0.24678271006754454,destabilizing
+RBM39,MAGI3,0.2120760776390036,destabilizing
+RBM39,SBF2,0.10276523082312156,destabilizing
+RBM39,INPP4B,0.17068740737144183,destabilizing
+RBM39,ERC1,0.057830904552546636,destabilizing
+RBM39,PTPRS,0.21826730149713583,destabilizing
+RBM39,CBFA2T2,0.09201001800186985,destabilizing
+RBM39,SPDYE3,0.1821830577056871,destabilizing
+RBM39,TMEM178B,0.06540414499013082,destabilizing
+RBM39,DMD,0.23051999653202085,destabilizing
+RBM39,MCU,0.16244872940240956,destabilizing
+RBM39,SSH2,0.15665086424191008,destabilizing
+RBM39,DOCK3,0.23021780179922127,destabilizing
+RBM39,HS6ST3,0.1855297381655085,destabilizing
+RBM39,LPP,0.23647570936576864,destabilizing
+RBM39,STAG1,0.13353527395881046,destabilizing
+RBM39,CAPZA2,0.162161997293412,destabilizing
+RBM39,ADGRL3,0.09920779345128822,destabilizing
+RBM39,UBE2R2,0.19119001155200854,destabilizing
+RBM39,GTF2IRD1,0.17453757784365995,destabilizing
+RBM39,CCBE1,0.06936252068492486,destabilizing
+RBM39,TTC28,0.10592539017709407,destabilizing
+RBM39,SBNO1,0.09583193058251366,destabilizing
+RBM39,RIMS2,0.11356932931786072,destabilizing
+RBM39,IGF1R,0.0821221715329162,destabilizing
+RBM39,TRIO,0.07912161245191415,destabilizing
+RBM39,KCND2,0.05775687292474811,destabilizing
+RBM39,BTBD9,0.1971750826623132,destabilizing
+RBM39,CNGB1,0.2021091494504592,destabilizing
+RBM39,FMN2,0.14896489926610723,destabilizing
+RBM39,ENSG00000228222,0.2991543215811933,destabilizing
+RBM39,PRKN,0.2240372772106173,destabilizing
+RBM39,RASA2,0.2034685651818528,destabilizing
+RBM39,PPP1R12B,0.09951350106434038,destabilizing
+RBM39,FRMD4A,0.1296467056980899,destabilizing
+RBM39,CAMK1D,0.06475324250071286,destabilizing
+RBM39,SEMA6D,0.1516246851752296,destabilizing
+RBM39,WIPF2,0.18155921449529552,destabilizing
+RBM39,DLEU1,0.22315795971056923,destabilizing
+RBM39,TSHZ2,0.08690964592025263,destabilizing
+RBM39,MED13L,0.08786043550925128,destabilizing
+RBM39,KAZN,0.14349363581070704,destabilizing
+RBM39,KANSL1,0.09211980163156847,destabilizing
+RBM39,FRMD5,0.15734823622071423,destabilizing
+RBM39,LINC00174,0.17746687920317014,destabilizing
+RBM39,PPM1E,0.14751338583013437,destabilizing
+RBM39,ARL3,0.09815561185875818,destabilizing
+RBM39,MBD5,0.13940359690683046,destabilizing
+RBM39,ELAVL3,0.1701393493400984,destabilizing
+RBM39,SLIT2,0.23235413384534412,destabilizing
+RBM39,CLASP1,0.11387821641080743,destabilizing
+RBM39,UNC5C,0.16583852301173702,destabilizing
+RBM39,CACNA2D3,-0.0838903986864323,stabilizing
+RBM39,RC3H1,0.1268404878228857,destabilizing
+RBM39,NEGR1,0.17080773415225065,destabilizing
+RBM39,ENOX1,0.2667905102086035,destabilizing
+RBM39,SCUBE1,0.10719646675017233,destabilizing
+RBM39,GPHN,0.13931827691883547,destabilizing
+RBM39,NAV3,0.20188775739081893,destabilizing
+RBM39,TOMM22,0.19394351853506964,destabilizing
+RBM39,MAGI2,0.06872321012033666,destabilizing
+RBM39,LSAMP,0.10801041991655495,destabilizing
+RBM39,AKAP6,0.18684488707734836,destabilizing
+RBM39,TMED2,0.1202082472969939,destabilizing
+RBM39,ZBTB20,0.16321835170928606,destabilizing
+RBM39,GRIK2,0.1422030021812233,destabilizing
+RBM39,SOX5,0.12537517088541955,destabilizing
+RBM39,LRRC37A3,0.25378198742983904,destabilizing
+RBM39,TMEM132C,0.055566236685437545,destabilizing
+RBM39,EYS,0.11286917484688008,destabilizing
+RBM39,ARID1B,0.10841063538956294,destabilizing
+RBM39,PRKCE,0.11511614485546053,destabilizing
+RBM39,RBFOX1,-0.11513921964722708,stabilizing
+RBM39,SDK1,0.08369980948709597,destabilizing
+RBM39,NRG1,0.05531718219927604,destabilizing
+RBM39,MLLT3,0.261933381341859,destabilizing
+RBM39,FMN1,0.08684383639861819,destabilizing
+RBM39,ADGRB3,0.09597553646503014,destabilizing
+RBM39,ROBO1,0.1530085599585113,destabilizing
+RBM39,SYPL1,0.08376260615870071,destabilizing
+RBM39,PTPRD,0.13846086534273286,destabilizing
+RBM39,FAM155A,0.14802282811417003,destabilizing
+RBM39,LARP1B,0.16552354494936966,destabilizing
+SRSF3,TRERF1,0.2221988253478126,destabilizing
+SRSF3,SORCS1,0.1357403555389706,destabilizing
+SRSF3,NCOA1,0.07380031686655292,destabilizing
+SRSF3,COPA,0.08205304049499397,destabilizing
+SRSF3,FCHSD2,0.08780587092529943,destabilizing
+SRSF3,PDE3A,0.1919685260253324,destabilizing
+SRSF3,UNC79,0.207586480601078,destabilizing
+SRSF3,DOC2B,0.148131517568564,destabilizing
+SRSF3,TMTC2,0.23508849869183773,destabilizing
+SRSF3,KALRN,0.12805182531767256,destabilizing
+SRSF3,CHD1,0.0948281106538144,destabilizing
+SRSF3,UBE2E2,0.09779523749118467,destabilizing
+SRSF3,PPARD,0.10860181271599907,destabilizing
+SRSF3,TOX,0.10652923508169702,destabilizing
+SRSF3,BRAF,0.10285078990950114,destabilizing
+SRSF3,RYR2,0.20934889902617987,destabilizing
+SRSF3,MTMR7,0.20646043603361933,destabilizing
+SRSF3,EIF4E,0.23391893881460707,destabilizing
+SRSF3,SOX11,0.08732905248434833,destabilizing
+SRSF3,EPB41L4B,0.08908295844086198,destabilizing
+SRSF3,CACNA1B,0.12119731386791077,destabilizing
+SRSF3,TBC1D5,0.0624382971978803,destabilizing
+SRSF3,WSB1,0.05498702919418591,destabilizing
+SRSF3,LRRTM4,0.12214293002638651,destabilizing
+SRSF3,SIRPA,0.15226220809294616,destabilizing
+SRSF3,PTEN,0.1258354629362296,destabilizing
+SRSF3,FRY,0.26505189118346484,destabilizing
+SRSF3,RUNX1T1,0.0889619848920359,destabilizing
+SRSF3,MACROD2,0.1970236149562263,destabilizing
+SRSF3,SHANK2,0.277591290707965,destabilizing
+SRSF3,CDK12,0.2755086143233137,destabilizing
+SRSF3,RFX7,0.19910829979717748,destabilizing
+SRSF3,UBR5,0.0714567356102544,destabilizing
+SRSF3,JARID2,0.1088529082550248,destabilizing
+SRSF3,MPHOSPH8,0.19299042433975971,destabilizing
+SRSF3,DIP2C,0.13138364138718267,destabilizing
+SRSF3,UBR3,0.11025736803996396,destabilizing
+SRSF3,DLG2,0.1307620711797404,destabilizing
+SRSF3,CHST12,0.3020580875494834,destabilizing
+SRSF3,EML5,0.2201481439864582,destabilizing
+SRSF3,CENPP,0.4092786805286205,destabilizing
+SRSF3,PSME4,0.1869293086023095,destabilizing
+SRSF3,TMEM106B,0.1896863638322485,destabilizing
+SRSF3,RABGAP1L,0.06314256574812244,destabilizing
+SRSF3,EPHA5,0.14473927328331837,destabilizing
+SRSF3,KCNB2,0.2801458039605575,destabilizing
+SRSF3,ZNF83,0.14377907981465032,destabilizing
+SRSF3,SOX6,0.1439173681244193,destabilizing
+SRSF3,ZNF521,0.18672429825607026,destabilizing
+SRSF3,PLEKHA5,0.11672487349922306,destabilizing
+SRSF3,NOVA1,0.25526276872673204,destabilizing
+SRSF3,CCNY,0.20847174423361545,destabilizing
+SRSF3,ARIH1,0.14987798165966965,destabilizing
+SRSF3,EPB41L5,0.12026535828875436,destabilizing
+SRSF3,GPR158,0.18789169247439033,destabilizing
+SRSF3,NCOA2,0.10562739227788742,destabilizing
+SRSF3,ALK,0.3173823183783115,destabilizing
+SRSF3,ARHGAP26,0.08032771401478019,destabilizing
+SRSF3,CTNND2,0.07428591042643581,destabilizing
+SRSF3,IFT172,0.183566521317812,destabilizing
+SRSF3,CCNT1,0.11469190784954938,destabilizing
+SRSF3,DTWD2,0.33396413549697024,destabilizing
+SRSF3,SIK3,0.19198174603098575,destabilizing
+SRSF3,CPEB3,0.22066340495373624,destabilizing
+SRSF3,CADM2,0.10363606526785141,destabilizing
+SRSF3,XKR6,0.20202991960064032,destabilizing
+SRSF3,RMND5A,0.06669555766750342,destabilizing
+SRSF3,CADPS,0.10397749220202868,destabilizing
+SRSF3,FGF13,0.09478237609792228,destabilizing
+SRSF3,TCF20,0.17999164321782996,destabilizing
+SRSF3,CDKAL1,0.12235821761784015,destabilizing
+SRSF3,DGKI,0.1781147753888703,destabilizing
+SRSF3,EXOC6B,0.26677731652025716,destabilizing
+SRSF3,MAGI3,0.1868391536334345,destabilizing
+SRSF3,SBF2,0.09853997768123166,destabilizing
+SRSF3,INPP4B,0.13866109713325395,destabilizing
+SRSF3,PTPRS,0.19666578338570598,destabilizing
+SRSF3,CBFA2T2,0.07848713639044298,destabilizing
+SRSF3,SPDYE3,0.1282664945999353,destabilizing
+SRSF3,TMEM178B,0.09282398674054658,destabilizing
+SRSF3,DMD,0.26893531921074093,destabilizing
+SRSF3,EIF4G3,0.07756751210583533,destabilizing
+SRSF3,MCU,0.18425171277570276,destabilizing
+SRSF3,SSH2,0.15200399980382087,destabilizing
+SRSF3,DOCK3,0.2287853169071147,destabilizing
+SRSF3,HS6ST3,0.14172836871983868,destabilizing
+SRSF3,LPP,0.1550928195288778,destabilizing
+SRSF3,STAG1,0.12877721639867232,destabilizing
+SRSF3,CAPZA2,0.1654306917231939,destabilizing
+SRSF3,ADGRL3,0.08717962978384626,destabilizing
+SRSF3,PHACTR1,0.12949971934450305,destabilizing
+SRSF3,UBE2R2,0.17048273876013628,destabilizing
+SRSF3,GTF2IRD1,0.12354005102269053,destabilizing
+SRSF3,CCBE1,0.06296906992371776,destabilizing
+SRSF3,FTX,0.06783523998662361,destabilizing
+SRSF3,JMJD1C,0.07622257808637778,destabilizing
+SRSF3,TTC28,0.1452415394443281,destabilizing
+SRSF3,SBNO1,0.07528481652142995,destabilizing
+SRSF3,RIMS2,0.11966358006010946,destabilizing
+SRSF3,IGF1R,0.06064501487435406,destabilizing
+SRSF3,BTBD9,0.1618401207673114,destabilizing
+SRSF3,CNGB1,0.18223741350378772,destabilizing
+SRSF3,FMN2,0.15339054974496316,destabilizing
+SRSF3,ENSG00000228222,0.29588368023180034,destabilizing
+SRSF3,ATXN1,0.07232640898272312,destabilizing
+SRSF3,SYN3,0.09700830292351578,destabilizing
+SRSF3,PRKN,0.1877066156358321,destabilizing
+SRSF3,RASA2,0.19459633510947094,destabilizing
+SRSF3,PPP1R12B,0.12340516808085923,destabilizing
+SRSF3,FRMD4A,0.12159516576903069,destabilizing
+SRSF3,CAMK1D,0.07261281906053889,destabilizing
+SRSF3,SEMA6D,0.1806614674415487,destabilizing
+SRSF3,WIPF2,0.18978683385212564,destabilizing
+SRSF3,DLEU1,0.2376595818468475,destabilizing
+SRSF3,TSHZ2,0.1217928176270903,destabilizing
+SRSF3,MED13L,0.11310066057252943,destabilizing
+SRSF3,KAZN,0.15664240116892234,destabilizing
+SRSF3,KANSL1,0.11276609649601692,destabilizing
+SRSF3,FRMD5,0.16793093318275473,destabilizing
+SRSF3,LINC00174,0.17160478784195354,destabilizing
+SRSF3,PPM1E,0.13642426834889326,destabilizing
+SRSF3,ARL3,0.1449991453078381,destabilizing
+SRSF3,MBD5,0.15420317895415683,destabilizing
+SRSF3,ELAVL3,0.15844505850120758,destabilizing
+SRSF3,SLIT2,0.1981251211353916,destabilizing
+SRSF3,CLASP1,0.14313969788551564,destabilizing
+SRSF3,UNC5C,0.1813192011179073,destabilizing
+SRSF3,CACNA2D3,-0.0709320398379863,stabilizing
+SRSF3,RC3H1,0.1085936109549655,destabilizing
+SRSF3,NEGR1,0.22544993362700816,destabilizing
+SRSF3,ENOX1,0.25087093295838403,destabilizing
+SRSF3,SCUBE1,0.07879819805797722,destabilizing
+SRSF3,GPHN,0.1347719902277359,destabilizing
+SRSF3,NAV3,0.1932974951439807,destabilizing
+SRSF3,EBF1,0.06935151280169974,destabilizing
+SRSF3,TOMM22,0.22921495073410564,destabilizing
+SRSF3,MBNL2,0.08388713416878031,destabilizing
+SRSF3,ANKFN1,0.08819536986742477,destabilizing
+SRSF3,MAGI2,0.06743025436135738,destabilizing
+SRSF3,LSAMP,0.11322726525525881,destabilizing
+SRSF3,AKAP6,0.18262499296959817,destabilizing
+SRSF3,TMED2,0.13015023375328122,destabilizing
+SRSF3,ZBTB20,0.17330473385614,destabilizing
+SRSF3,GRIK2,0.1500370998706149,destabilizing
+SRSF3,SOX5,0.11292481022326403,destabilizing
+SRSF3,LRRC37A3,0.22750110682114713,destabilizing
+SRSF3,TMEM132C,0.07887623550269686,destabilizing
+SRSF3,EYS,0.13857445962599957,destabilizing
+SRSF3,ARID1B,0.10862864566970742,destabilizing
+SRSF3,PRKCE,0.10233053969250736,destabilizing
+SRSF3,RBFOX1,-0.08618547979978751,stabilizing
+SRSF3,SDK1,0.08600784938092662,destabilizing
+SRSF3,NRG1,0.07930168571796599,destabilizing
+SRSF3,RORA,0.06598475475183048,destabilizing
+SRSF3,MLLT3,0.29111353240585336,destabilizing
+SRSF3,FMN1,0.091824438870805,destabilizing
+SRSF3,ADGRB3,0.08240244807912557,destabilizing
+SRSF3,ROBO1,0.12745785224958633,destabilizing
+SRSF3,SYPL1,0.12942069355423852,destabilizing
+SRSF3,PTPRD,0.15332053624443462,destabilizing
+SRSF3,FAM155A,0.19525881582871793,destabilizing
+SRSF3,LARP1B,0.147695660963295,destabilizing
+SRSF4,TRERF1,0.10132192711595314,destabilizing
+SRSF4,SORCS1,0.06426108520490235,destabilizing
+SRSF4,UNC79,0.12750275718454812,destabilizing
+SRSF4,DOC2B,0.06324218322959682,destabilizing
+SRSF4,TMTC2,0.11797403179501634,destabilizing
+SRSF4,KALRN,0.07474163181611126,destabilizing
+SRSF4,PPARD,0.07095122400146975,destabilizing
+SRSF4,RYR2,0.118515895859407,destabilizing
+SRSF4,MTMR7,0.1263135648094664,destabilizing
+SRSF4,EIF4E,0.1366388422699583,destabilizing
+SRSF4,CACNA1B,0.09929447580841463,destabilizing
+SRSF4,LRRTM4,0.0681995313818645,destabilizing
+SRSF4,SIRPA,0.1034804296013183,destabilizing
+SRSF4,FRY,0.15550188329481712,destabilizing
+SRSF4,MACROD2,0.11747561931537176,destabilizing
+SRSF4,SHANK2,0.16706320863625604,destabilizing
+SRSF4,CDK12,0.18186559295825855,destabilizing
+SRSF4,RFX7,0.10903113671681441,destabilizing
+SRSF4,MPHOSPH8,0.1183576832325959,destabilizing
+SRSF4,DIP2C,0.06719395249971762,destabilizing
+SRSF4,DLG2,0.08120485084857118,destabilizing
+SRSF4,CHST12,0.21969249141575148,destabilizing
+SRSF4,EML5,0.09693092590900494,destabilizing
+SRSF4,CENPP,0.17236897389571507,destabilizing
+SRSF4,PSME4,0.07304880259214358,destabilizing
+SRSF4,TMEM106B,0.11379620554896683,destabilizing
+SRSF4,EPHA5,0.09147584109991738,destabilizing
+SRSF4,KCNB2,0.1664977413914098,destabilizing
+SRSF4,ZNF83,0.10403731989375542,destabilizing
+SRSF4,SOX6,0.08937662566770602,destabilizing
+SRSF4,ZNF521,0.11574817661747876,destabilizing
+SRSF4,NOVA1,0.12230980464591948,destabilizing
+SRSF4,CCNY,0.10402696725836225,destabilizing
+SRSF4,ARIH1,0.08751469594814291,destabilizing
+SRSF4,EPB41L5,0.07918581493599285,destabilizing
+SRSF4,GPR158,0.08845430623660332,destabilizing
+SRSF4,ALK,0.1537676440454039,destabilizing
+SRSF4,IFT172,0.10464345925375661,destabilizing
+SRSF4,CCNT1,0.06587420882862728,destabilizing
+SRSF4,DTWD2,0.1677129634878861,destabilizing
+SRSF4,SIK3,0.07924357717426865,destabilizing
+SRSF4,CPEB3,0.11484775781286202,destabilizing
+SRSF4,XKR6,0.11534889334056936,destabilizing
+SRSF4,CADPS,0.06348118029617514,destabilizing
+SRSF4,FGF13,0.060671614810181164,destabilizing
+SRSF4,TCF20,0.08758876527195897,destabilizing
+SRSF4,CDKAL1,0.0767395424775092,destabilizing
+SRSF4,DGKI,0.09554616373193975,destabilizing
+SRSF4,EXOC6B,0.15514989893641928,destabilizing
+SRSF4,MAGI3,0.11586755570620437,destabilizing
+SRSF4,SBF2,0.06803672071187108,destabilizing
+SRSF4,INPP4B,0.08860233833400669,destabilizing
+SRSF4,PTPRS,0.14712297987718967,destabilizing
+SRSF4,DMD,0.13283793738182265,destabilizing
+SRSF4,MCU,0.09098481843585264,destabilizing
+SRSF4,DOCK3,0.12831071732500596,destabilizing
+SRSF4,HS6ST3,0.09628599561636528,destabilizing
+SRSF4,STAG1,0.07832545982143276,destabilizing
+SRSF4,CAPZA2,0.12417079968399727,destabilizing
+SRSF4,UBE2R2,0.09582739675093335,destabilizing
+SRSF4,GTF2IRD1,0.06611877019958347,destabilizing
+SRSF4,RIMS2,0.060448782021897796,destabilizing
+SRSF4,CNGB1,0.11250010130215281,destabilizing
+SRSF4,FMN2,0.06473125852607049,destabilizing
+SRSF4,ENSG00000228222,0.18427833767245136,destabilizing
+SRSF4,PRKN,0.11781383713252215,destabilizing
+SRSF4,RASA2,0.13075766886846404,destabilizing
+SRSF4,FRMD4A,0.06749961440977843,destabilizing
+SRSF4,SEMA6D,0.07776561402132089,destabilizing
+SRSF4,WIPF2,0.10586184806513912,destabilizing
+SRSF4,DLEU1,0.10910055721896625,destabilizing
+SRSF4,TSHZ2,0.0655491289031031,destabilizing
+SRSF4,KAZN,0.07845601895363524,destabilizing
+SRSF4,FRMD5,0.09266082020532637,destabilizing
+SRSF4,LINC00174,0.10014005074678461,destabilizing
+SRSF4,ARL3,0.07588000119844919,destabilizing
+SRSF4,MBD5,0.0600270279318112,destabilizing
+SRSF4,ELAVL3,0.1139275354708102,destabilizing
+SRSF4,SLIT2,0.11882665000890458,destabilizing
+SRSF4,CLASP1,0.08165527294304503,destabilizing
+SRSF4,UNC5C,0.10623493304396826,destabilizing
+SRSF4,NEGR1,0.10217226643582579,destabilizing
+SRSF4,ENOX1,0.13116027161860394,destabilizing
+SRSF4,GPHN,0.07248334195422564,destabilizing
+SRSF4,NAV3,0.0906797834570871,destabilizing
+SRSF4,TOMM22,0.11890762179861993,destabilizing
+SRSF4,LSAMP,0.06101077057212273,destabilizing
+SRSF4,AKAP6,0.10567253947563056,destabilizing
+SRSF4,TMED2,0.08066512665125945,destabilizing
+SRSF4,ZBTB20,0.07591438347353031,destabilizing
+SRSF4,GRIK2,0.07482250631465305,destabilizing
+SRSF4,LRRC37A3,0.12907040288482763,destabilizing
+SRSF4,EYS,0.08851342903195174,destabilizing
+SRSF4,ARID1B,0.07529455273929496,destabilizing
+SRSF4,PRKCE,0.08137543787942762,destabilizing
+SRSF4,RBFOX1,-0.060056884061394075,stabilizing
+SRSF4,MLLT3,0.17807994218554346,destabilizing
+SRSF4,ROBO1,0.0837675537123918,destabilizing
+SRSF4,SYPL1,0.07216243036622692,destabilizing
+SRSF4,PTPRD,0.0668874722639655,destabilizing
+SRSF4,FAM155A,0.11930562740934841,destabilizing
+SRSF4,LARP1B,0.0800756063522092,destabilizing
+SRSF5,TRERF1,0.13834734779333313,destabilizing
+SRSF5,SORCS1,0.1017481827779521,destabilizing
+SRSF5,FCHSD2,0.08707809335390408,destabilizing
+SRSF5,PDE3A,0.16162976601762422,destabilizing
+SRSF5,UNC79,0.1741795912480174,destabilizing
+SRSF5,DOC2B,0.11077518447347331,destabilizing
+SRSF5,TMTC2,0.14743256324568785,destabilizing
+SRSF5,KALRN,0.1110509367235366,destabilizing
+SRSF5,CHD1,0.0951011795218285,destabilizing
+SRSF5,UBE2E2,0.06640246214826619,destabilizing
+SRSF5,PPARD,0.07229206916184062,destabilizing
+SRSF5,RYR2,0.12590029596974517,destabilizing
+SRSF5,MTMR7,0.16078889919067282,destabilizing
+SRSF5,EIF4E,0.17566935248802137,destabilizing
+SRSF5,EPB41L4B,0.10357606133960265,destabilizing
+SRSF5,CACNA1B,0.10874613099958216,destabilizing
+SRSF5,LRRTM4,0.12850128927216467,destabilizing
+SRSF5,SIRPA,0.14367694495616123,destabilizing
+SRSF5,PTEN,0.10745929392621557,destabilizing
+SRSF5,FRY,0.17203678722860258,destabilizing
+SRSF5,MACROD2,0.15110000874846635,destabilizing
+SRSF5,SHANK2,0.21545538592916574,destabilizing
+SRSF5,CDK12,0.2252770688569138,destabilizing
+SRSF5,RFX7,0.17057330222568484,destabilizing
+SRSF5,UBR5,0.06569001235699717,destabilizing
+SRSF5,JARID2,0.06911727022387194,destabilizing
+SRSF5,MPHOSPH8,0.12560428865291945,destabilizing
+SRSF5,DIP2C,0.117457525716209,destabilizing
+SRSF5,ZNF423,0.05584918345743737,destabilizing
+SRSF5,UBR3,0.10385984322929556,destabilizing
+SRSF5,MGAT5,0.05009669614085667,destabilizing
+SRSF5,DLG2,0.11757424782687796,destabilizing
+SRSF5,CHST12,0.2279204936821902,destabilizing
+SRSF5,EML5,0.14428722424789772,destabilizing
+SRSF5,CENPP,0.1396492613378111,destabilizing
+SRSF5,PSME4,0.15350369722182483,destabilizing
+SRSF5,TMEM106B,0.16465233990544884,destabilizing
+SRSF5,EPHA5,0.11461094700906792,destabilizing
+SRSF5,KCNB2,0.15723600766853912,destabilizing
+SRSF5,ZNF83,0.1068462813016775,destabilizing
+SRSF5,SOX6,0.07998132329970835,destabilizing
+SRSF5,ZNF521,0.12071176386008234,destabilizing
+SRSF5,PLEKHA5,0.10462183743362893,destabilizing
+SRSF5,NOVA1,0.18824321223269105,destabilizing
+SRSF5,CCNY,0.14086118448234417,destabilizing
+SRSF5,ARIH1,0.09103134571899286,destabilizing
+SRSF5,EPB41L5,0.11322875969291596,destabilizing
+SRSF5,GPR158,0.162430545192072,destabilizing
+SRSF5,NCOA2,0.12468819084168101,destabilizing
+SRSF5,MARCKS,0.05935950845456454,destabilizing
+SRSF5,ALK,0.12725507096190913,destabilizing
+SRSF5,ACACA,0.0721655741064546,destabilizing
+SRSF5,ARHGAP26,0.05752329599425094,destabilizing
+SRSF5,CTNND2,0.058514602493669625,destabilizing
+SRSF5,IFT172,0.14763863368219762,destabilizing
+SRSF5,CCNT1,0.08239565043689674,destabilizing
+SRSF5,DTWD2,0.17705408092604885,destabilizing
+SRSF5,SIK3,0.10267999126396979,destabilizing
+SRSF5,CPEB3,0.18320344675985298,destabilizing
+SRSF5,CADM2,0.09431235673951117,destabilizing
+SRSF5,XKR6,0.16577567142473987,destabilizing
+SRSF5,CADPS,0.07116546387320413,destabilizing
+SRSF5,TCF20,0.1429435393999108,destabilizing
+SRSF5,CDKAL1,0.07595660548459866,destabilizing
+SRSF5,DGKI,0.10765793881329007,destabilizing
+SRSF5,EXOC6B,0.17452221729803022,destabilizing
+SRSF5,MAGI3,0.14108250226578228,destabilizing
+SRSF5,SBF2,0.08234756869357594,destabilizing
+SRSF5,INPP4B,0.12580080515390493,destabilizing
+SRSF5,ERC1,0.05502117708750193,destabilizing
+SRSF5,PTPRS,0.18465853077237537,destabilizing
+SRSF5,SPDYE3,0.13212670448895258,destabilizing
+SRSF5,TMEM178B,0.06157929000456532,destabilizing
+SRSF5,DMD,0.2026638218540763,destabilizing
+SRSF5,MCU,0.11970586341778344,destabilizing
+SRSF5,SSH2,0.12077460664424208,destabilizing
+SRSF5,DOCK3,0.1568399255860237,destabilizing
+SRSF5,HS6ST3,0.15882204188139154,destabilizing
+SRSF5,LPP,0.1783281511553963,destabilizing
+SRSF5,STAG1,0.12130008961616241,destabilizing
+SRSF5,CAPZA2,0.14219685376665228,destabilizing
+SRSF5,ADGRL3,0.06648121199795008,destabilizing
+SRSF5,UBE2R2,0.15290897189206606,destabilizing
+SRSF5,GTF2IRD1,0.13525197776764988,destabilizing
+SRSF5,CCBE1,0.05623103886808766,destabilizing
+SRSF5,TTC28,0.08631181128184283,destabilizing
+SRSF5,SBNO1,0.06409613029728936,destabilizing
+SRSF5,RIMS2,0.08547540133375965,destabilizing
+SRSF5,IGF1R,0.05908357998843098,destabilizing
+SRSF5,TRIO,0.05941861837160039,destabilizing
+SRSF5,BTBD9,0.13722010123870135,destabilizing
+SRSF5,CNGB1,0.18284965415235857,destabilizing
+SRSF5,FMN2,0.11413867994020166,destabilizing
+SRSF5,ENSG00000228222,0.2042749658952984,destabilizing
+SRSF5,PRKN,0.16213032785099551,destabilizing
+SRSF5,RASA2,0.15556660521153662,destabilizing
+SRSF5,PPP1R12B,0.08359973244226228,destabilizing
+SRSF5,FRMD4A,0.09882804913006238,destabilizing
+SRSF5,SEMA6D,0.09390156901520144,destabilizing
+SRSF5,WIPF2,0.1283035625915495,destabilizing
+SRSF5,DLEU1,0.21529494812327984,destabilizing
+SRSF5,TSHZ2,0.08303918264404866,destabilizing
+SRSF5,MED13L,0.07180213449399152,destabilizing
+SRSF5,KAZN,0.11630223087622212,destabilizing
+SRSF5,KANSL1,0.07334479454915749,destabilizing
+SRSF5,FRMD5,0.11804381934190677,destabilizing
+SRSF5,LINC00174,0.13137785727936716,destabilizing
+SRSF5,PPM1E,0.11517697707533982,destabilizing
+SRSF5,ARL3,0.09567945191490199,destabilizing
+SRSF5,MBD5,0.09252279603812592,destabilizing
+SRSF5,ELAVL3,0.13475401953265095,destabilizing
+SRSF5,SLIT2,0.20891182584188348,destabilizing
+SRSF5,CLASP1,0.07626020980608,destabilizing
+SRSF5,UNC5C,0.152554944048964,destabilizing
+SRSF5,CACNA2D3,-0.06033990006659017,stabilizing
+SRSF5,RC3H1,0.07952235868338293,destabilizing
+SRSF5,NEGR1,0.1348136758252906,destabilizing
+SRSF5,ENOX1,0.20216641956168774,destabilizing
+SRSF5,SCUBE1,0.09569938972980815,destabilizing
+SRSF5,GPHN,0.09897450672577311,destabilizing
+SRSF5,NAV3,0.17215456117379438,destabilizing
+SRSF5,TOMM22,0.16791033733350033,destabilizing
+SRSF5,LSAMP,0.09346830095939693,destabilizing
+SRSF5,AKAP6,0.12640254795673062,destabilizing
+SRSF5,TMED2,0.08202263709035006,destabilizing
+SRSF5,ZBTB20,0.11120591985118619,destabilizing
+SRSF5,GRIK2,0.12673975051978323,destabilizing
+SRSF5,SOX5,0.09186066093367212,destabilizing
+SRSF5,LRRC37A3,0.18824302067872,destabilizing
+SRSF5,EYS,0.09700237924215009,destabilizing
+SRSF5,ARID1B,0.09816021076097166,destabilizing
+SRSF5,PRKCE,0.07614270043542605,destabilizing
+SRSF5,RBFOX1,-0.09900372915682851,stabilizing
+SRSF5,SDK1,0.0673666942476659,destabilizing
+SRSF5,MLLT3,0.22425353737615594,destabilizing
+SRSF5,FMN1,0.060134164257993825,destabilizing
+SRSF5,ADGRB3,0.08986732993866434,destabilizing
+SRSF5,ROBO1,0.12743300005170005,destabilizing
+SRSF5,SYPL1,0.06382208370731833,destabilizing
+SRSF5,PTPRD,0.11622013015906628,destabilizing
+SRSF5,FAM155A,0.1624212030496499,destabilizing
+SRSF5,LARP1B,0.12509650552493612,destabilizing
+SRSF7,TRERF1,0.1572654955957037,destabilizing
+SRSF7,SORCS1,0.12557953308734052,destabilizing
+SRSF7,NCOA1,0.05928195127056332,destabilizing
+SRSF7,FCHSD2,0.10460149326388136,destabilizing
+SRSF7,PDE3A,0.15149590207387728,destabilizing
+SRSF7,UNC79,0.2184488897941353,destabilizing
+SRSF7,DOC2B,0.13281965407008803,destabilizing
+SRSF7,TMTC2,0.19196382070883047,destabilizing
+SRSF7,KALRN,0.14280740891079827,destabilizing
+SRSF7,CHD1,0.09325606820488627,destabilizing
+SRSF7,UBE2E2,0.0735107411949788,destabilizing
+SRSF7,PPARD,0.12041661974031409,destabilizing
+SRSF7,TOX,0.110937186967764,destabilizing
+SRSF7,BRAF,0.07842688241923348,destabilizing
+SRSF7,RYR2,0.18467211497755226,destabilizing
+SRSF7,MTMR7,0.21263539071695417,destabilizing
+SRSF7,EIF4E,0.23918830420281387,destabilizing
+SRSF7,SOX11,0.07080504904782768,destabilizing
+SRSF7,EPB41L4B,0.099459884497361,destabilizing
+SRSF7,CACNA1B,0.11151443646074216,destabilizing
+SRSF7,WSB1,0.0676261358081825,destabilizing
+SRSF7,LRRTM4,0.10268712468952089,destabilizing
+SRSF7,SIRPA,0.1383545740156962,destabilizing
+SRSF7,PTEN,0.11926252067121083,destabilizing
+SRSF7,FRY,0.21889195223178923,destabilizing
+SRSF7,RUNX1T1,0.073534356544689,destabilizing
+SRSF7,MACROD2,0.19694180484982185,destabilizing
+SRSF7,SHANK2,0.24681505024930164,destabilizing
+SRSF7,CDK12,0.28719343284557497,destabilizing
+SRSF7,BMPR1B,0.04968942280767033,destabilizing
+SRSF7,RFX7,0.15535996932765003,destabilizing
+SRSF7,UBR5,0.07902343694169703,destabilizing
+SRSF7,JARID2,0.09229051181744759,destabilizing
+SRSF7,MPHOSPH8,0.16385762034390078,destabilizing
+SRSF7,DIP2C,0.11894804536751648,destabilizing
+SRSF7,ZNF423,0.0832658010210454,destabilizing
+SRSF7,UBR3,0.11483284696497444,destabilizing
+SRSF7,MGAT5,0.050815539005109316,destabilizing
+SRSF7,DLG2,0.10793814794111771,destabilizing
+SRSF7,CHST12,0.2976274199711856,destabilizing
+SRSF7,EML5,0.20326817200125974,destabilizing
+SRSF7,CENPP,0.35764031129206075,destabilizing
+SRSF7,PSME4,0.17533918504293225,destabilizing
+SRSF7,TMEM106B,0.1503586754639621,destabilizing
+SRSF7,RABGAP1L,0.08506405287522215,destabilizing
+SRSF7,EPHA5,0.1268789579269287,destabilizing
+SRSF7,KCNB2,0.24100016159685378,destabilizing
+SRSF7,ZNF83,0.1615512069747551,destabilizing
+SRSF7,SOX6,0.13331672703088096,destabilizing
+SRSF7,ZNF521,0.17336227572971136,destabilizing
+SRSF7,PLEKHA5,0.11497147040538006,destabilizing
+SRSF7,NOVA1,0.20846664456970518,destabilizing
+SRSF7,CCNY,0.19926811299149075,destabilizing
+SRSF7,ARIH1,0.12286423768957194,destabilizing
+SRSF7,EPB41L5,0.09639387077712744,destabilizing
+SRSF7,GPR158,0.15428126716140267,destabilizing
+SRSF7,NCOA2,0.092317381710021,destabilizing
+SRSF7,MARCKS,0.06748571187694248,destabilizing
+SRSF7,ALK,0.30079437760933675,destabilizing
+SRSF7,ARHGAP26,0.06575277453392354,destabilizing
+SRSF7,CTNND2,0.06643647842822181,destabilizing
+SRSF7,IFT172,0.17879251450732145,destabilizing
+SRSF7,CCNT1,0.11936442760160007,destabilizing
+SRSF7,DTWD2,0.2829929458357405,destabilizing
+SRSF7,SIK3,0.1656145287166811,destabilizing
+SRSF7,CPEB3,0.18709157783932898,destabilizing
+SRSF7,CADM2,0.11368841334089928,destabilizing
+SRSF7,XKR6,0.20876246317767178,destabilizing
+SRSF7,RMND5A,0.06295409741349654,destabilizing
+SRSF7,CADPS,0.11132757858668937,destabilizing
+SRSF7,FGF13,0.09323374698216147,destabilizing
+SRSF7,TCF20,0.14528169635543228,destabilizing
+SRSF7,CDKAL1,0.12177813377244455,destabilizing
+SRSF7,DGKI,0.1481798895448952,destabilizing
+SRSF7,EXOC6B,0.2042943387462103,destabilizing
+SRSF7,MAGI3,0.2019673501783391,destabilizing
+SRSF7,SBF2,0.09593327702989772,destabilizing
+SRSF7,INPP4B,0.12988267346595547,destabilizing
+SRSF7,PTPRS,0.1759362112966076,destabilizing
+SRSF7,CBFA2T2,0.07431975626732928,destabilizing
+SRSF7,SPDYE3,0.11021706823141603,destabilizing
+SRSF7,TMEM178B,0.09984124553463357,destabilizing
+SRSF7,DMD,0.2621552165843023,destabilizing
+SRSF7,EIF4G3,0.09276108924457453,destabilizing
+SRSF7,MCU,0.15196440446987958,destabilizing
+SRSF7,SSH2,0.13075350774015623,destabilizing
+SRSF7,DOCK3,0.22717422732958445,destabilizing
+SRSF7,HS6ST3,0.10175990471247105,destabilizing
+SRSF7,LPP,0.1251593945247833,destabilizing
+SRSF7,STAG1,0.1554218535162404,destabilizing
+SRSF7,CAPZA2,0.16476321182455303,destabilizing
+SRSF7,ADGRL3,0.09338451685030794,destabilizing
+SRSF7,PHACTR1,0.10648985002237697,destabilizing
+SRSF7,UBE2R2,0.18064563805300451,destabilizing
+SRSF7,GTF2IRD1,0.11293282027056568,destabilizing
+SRSF7,FTX,0.06336297043992818,destabilizing
+SRSF7,TTC28,0.14064646282137894,destabilizing
+SRSF7,SBNO1,0.0830169722859288,destabilizing
+SRSF7,RIMS2,0.13279773962764793,destabilizing
+SRSF7,IGF1R,0.05935315236474795,destabilizing
+SRSF7,BTBD9,0.13692247642154365,destabilizing
+SRSF7,CNGB1,0.1896360423731489,destabilizing
+SRSF7,FMN2,0.12608758191654315,destabilizing
+SRSF7,ENSG00000228222,0.2392220027494936,destabilizing
+SRSF7,ATXN1,0.07284584685841511,destabilizing
+SRSF7,SYN3,0.07313410383289347,destabilizing
+SRSF7,PRKN,0.14773342417242374,destabilizing
+SRSF7,RASA2,0.21221620717331507,destabilizing
+SRSF7,PPP1R12B,0.10540465120447172,destabilizing
+SRSF7,FRMD4A,0.1162795725657958,destabilizing
+SRSF7,CAMK1D,0.06252511474476781,destabilizing
+SRSF7,SEMA6D,0.1505533741996382,destabilizing
+SRSF7,WIPF2,0.2009504013392185,destabilizing
+SRSF7,DLEU1,0.20778026387295143,destabilizing
+SRSF7,TSHZ2,0.10425553273087622,destabilizing
+SRSF7,MED13L,0.10057811093711391,destabilizing
+SRSF7,KAZN,0.1368772367185814,destabilizing
+SRSF7,KANSL1,0.10968437450603255,destabilizing
+SRSF7,FRMD5,0.13030875593042304,destabilizing
+SRSF7,LINC00174,0.20267119834232147,destabilizing
+SRSF7,PPM1E,0.12966245208536695,destabilizing
+SRSF7,ARL3,0.1311710904573711,destabilizing
+SRSF7,MBD5,0.153735689476669,destabilizing
+SRSF7,ELAVL3,0.17571323522017024,destabilizing
+SRSF7,SLIT2,0.18335154210825919,destabilizing
+SRSF7,CLASP1,0.11867113555284413,destabilizing
+SRSF7,UNC5C,0.1702324012651578,destabilizing
+SRSF7,CACNA2D3,-0.05736468322842808,stabilizing
+SRSF7,RC3H1,0.07021136373825934,destabilizing
+SRSF7,NEGR1,0.18886911471936935,destabilizing
+SRSF7,ENOX1,0.21540824870544273,destabilizing
+SRSF7,SCUBE1,0.09769619568109097,destabilizing
+SRSF7,GPHN,0.0978230433477959,destabilizing
+SRSF7,NAV3,0.18879544737505663,destabilizing
+SRSF7,EBF1,0.06510989886998025,destabilizing
+SRSF7,TOMM22,0.19976207338941857,destabilizing
+SRSF7,MBNL2,0.07617628176526901,destabilizing
+SRSF7,ANKFN1,0.08066835111706724,destabilizing
+SRSF7,MAGI2,0.0810249879701358,destabilizing
+SRSF7,LSAMP,0.11927976095959995,destabilizing
+SRSF7,AKAP6,0.16151663106721134,destabilizing
+SRSF7,TMED2,0.13934919375296032,destabilizing
+SRSF7,ZBTB20,0.134744489357288,destabilizing
+SRSF7,GRIK2,0.14162481749142167,destabilizing
+SRSF7,SOX5,0.10617616125654646,destabilizing
+SRSF7,LRRC37A3,0.2413414533870466,destabilizing
+SRSF7,TMEM132C,0.06385984810820727,destabilizing
+SRSF7,EYS,0.12012082141811589,destabilizing
+SRSF7,ARID1B,0.12089036086567602,destabilizing
+SRSF7,PRKCE,0.11604341026413306,destabilizing
+SRSF7,RBFOX1,-0.09488049535990874,stabilizing
+SRSF7,SDK1,0.10554939620190468,destabilizing
+SRSF7,NRG1,0.05480064235470268,destabilizing
+SRSF7,RORA,0.056962527008541354,destabilizing
+SRSF7,MLLT3,0.2720985883826557,destabilizing
+SRSF7,FMN1,0.0868506450242517,destabilizing
+SRSF7,ADGRB3,0.08151550376949981,destabilizing
+SRSF7,ROBO1,0.1328147429341158,destabilizing
+SRSF7,SYPL1,0.09979175970920501,destabilizing
+SRSF7,PTPRD,0.15475502737109084,destabilizing
+SRSF7,FAM155A,0.17288488370943295,destabilizing
+SRSF7,LARP1B,0.1295341431743208,destabilizing
+SRSF9,TRERF1,0.3002075047971791,destabilizing
+SRSF9,SORCS1,0.1943431040303029,destabilizing
+SRSF9,NCOA1,0.08760334235357574,destabilizing
+SRSF9,COPA,0.13663048214078805,destabilizing
+SRSF9,FCHSD2,0.1320422083883396,destabilizing
+SRSF9,PDE3A,0.2466502120389638,destabilizing
+SRSF9,UNC79,0.29549845515303863,destabilizing
+SRSF9,DOC2B,0.19126916994299797,destabilizing
+SRSF9,TMTC2,0.25891740336171304,destabilizing
+SRSF9,KALRN,0.2035122814784687,destabilizing
+SRSF9,CHD1,0.14347535830102998,destabilizing
+SRSF9,PAK3,0.07707399211335385,destabilizing
+SRSF9,UBE2E2,0.12618275550302122,destabilizing
+SRSF9,PPARD,0.1741654517267921,destabilizing
+SRSF9,TOX,0.11069956360094726,destabilizing
+SRSF9,BRAF,0.12467082524435939,destabilizing
+SRSF9,RYR2,0.2719915662700261,destabilizing
+SRSF9,MTMR7,0.3054029837287622,destabilizing
+SRSF9,EIF4E,0.2850689087243856,destabilizing
+SRSF9,SOX11,0.07934745411879121,destabilizing
+SRSF9,EPB41L4B,0.16536492272468428,destabilizing
+SRSF9,CACNA1B,0.15727859162532262,destabilizing
+SRSF9,TBC1D5,0.11356690862752833,destabilizing
+SRSF9,WSB1,0.06668766594990008,destabilizing
+SRSF9,LRRTM4,0.16520302066317336,destabilizing
+SRSF9,SIRPA,0.15193041104936242,destabilizing
+SRSF9,PTEN,0.1837972488092515,destabilizing
+SRSF9,SPPL3,0.05842097161876749,destabilizing
+SRSF9,FRY,0.29140164547759667,destabilizing
+SRSF9,RUNX1T1,0.08518479918862708,destabilizing
+SRSF9,MACROD2,0.2581908922420794,destabilizing
+SRSF9,FOXN3,0.099405522368528,destabilizing
+SRSF9,SHANK2,0.32782744542067216,destabilizing
+SRSF9,CDK12,0.3211647430242524,destabilizing
+SRSF9,RFX7,0.2648500856724323,destabilizing
+SRSF9,UBR5,0.11559924822963427,destabilizing
+SRSF9,JARID2,0.14731515422173652,destabilizing
+SRSF9,MPHOSPH8,0.22075480923639085,destabilizing
+SRSF9,DIP2C,0.18051452927329412,destabilizing
+SRSF9,ZNF423,0.10867140254917686,destabilizing
+SRSF9,UBR3,0.20236194237183552,destabilizing
+SRSF9,MGAT5,0.08058796957279475,destabilizing
+SRSF9,DLG2,0.17230844312431023,destabilizing
+SRSF9,CHST12,0.3998337030546059,destabilizing
+SRSF9,EML5,0.30621145080319623,destabilizing
+SRSF9,CENPP,0.3557312549765216,destabilizing
+SRSF9,PSME4,0.24660994325578375,destabilizing
+SRSF9,TMEM106B,0.2513485576523856,destabilizing
+SRSF9,RABGAP1L,0.08581162380175598,destabilizing
+SRSF9,EPHA5,0.2003672480735621,destabilizing
+SRSF9,KCNB2,0.3198907930716636,destabilizing
+SRSF9,ZNF83,0.16899339554742376,destabilizing
+SRSF9,SOX6,0.16587143171077218,destabilizing
+SRSF9,ZNF521,0.22983636236143806,destabilizing
+SRSF9,PLEKHA5,0.16999209129418646,destabilizing
+SRSF9,NOVA1,0.29201002382288344,destabilizing
+SRSF9,CCNY,0.2229675379470766,destabilizing
+SRSF9,ARIH1,0.20824786183652982,destabilizing
+SRSF9,FAM171B,0.06548153474765997,destabilizing
+SRSF9,EPB41L5,0.1732867250324034,destabilizing
+SRSF9,GPR158,0.2602771821637321,destabilizing
+SRSF9,NCOA2,0.17675406221331527,destabilizing
+SRSF9,PRKCB,0.05841494536320602,destabilizing
+SRSF9,ALK,0.3470826121670856,destabilizing
+SRSF9,ACACA,0.10298300774820028,destabilizing
+SRSF9,ARHGAP26,0.10151850055821017,destabilizing
+SRSF9,CTNND2,0.12156676797609647,destabilizing
+SRSF9,IFT172,0.24000237853375103,destabilizing
+SRSF9,CCNT1,0.16360805568853604,destabilizing
+SRSF9,DTWD2,0.3474995634440101,destabilizing
+SRSF9,SIK3,0.23914455117826336,destabilizing
+SRSF9,CPEB3,0.26534183374351084,destabilizing
+SRSF9,CADM2,0.11239545180276721,destabilizing
+SRSF9,XKR6,0.2899616381464741,destabilizing
+SRSF9,RMND5A,0.08592144565919585,destabilizing
+SRSF9,CADPS,0.15029822923203567,destabilizing
+SRSF9,FGF13,0.11966371438449938,destabilizing
+SRSF9,TCF20,0.22692565686120703,destabilizing
+SRSF9,CDKAL1,0.18639027353276638,destabilizing
+SRSF9,DGKI,0.217064914890427,destabilizing
+SRSF9,EXOC6B,0.3053320305963325,destabilizing
+SRSF9,MAGI3,0.2516082972227251,destabilizing
+SRSF9,SBF2,0.14676882215041193,destabilizing
+SRSF9,INPP4B,0.19713445863868,destabilizing
+SRSF9,ERC1,0.09608669655973529,destabilizing
+SRSF9,PTPRS,0.20017519173796305,destabilizing
+SRSF9,CBFA2T2,0.13666313308147504,destabilizing
+SRSF9,SPDYE3,0.18821567781364767,destabilizing
+SRSF9,TMEM178B,0.14943261419709117,destabilizing
+SRSF9,KMT2C,0.08589962681115212,destabilizing
+SRSF9,CACNA2D1,0.06467112078507246,destabilizing
+SRSF9,DMD,0.3827253633409557,destabilizing
+SRSF9,EIF4G3,0.09658927991300556,destabilizing
+SRSF9,MCU,0.2267163181689885,destabilizing
+SRSF9,SSH2,0.20302022986690219,destabilizing
+SRSF9,DOCK3,0.2873293902664016,destabilizing
+SRSF9,HS6ST3,0.1990661210817766,destabilizing
+SRSF9,LPP,0.23125208551562867,destabilizing
+SRSF9,STAG1,0.17560060889990323,destabilizing
+SRSF9,CAPZA2,0.23698000720219234,destabilizing
+SRSF9,ADGRL3,0.12308249054639991,destabilizing
+SRSF9,PHACTR1,0.14666836297747068,destabilizing
+SRSF9,UBE2R2,0.24362928606340387,destabilizing
+SRSF9,GTF2IRD1,0.18440044292559057,destabilizing
+SRSF9,CCBE1,0.13222704104205812,destabilizing
+SRSF9,FTX,0.07692807585276037,destabilizing
+SRSF9,VAPA,0.05838844243040137,destabilizing
+SRSF9,JMJD1C,0.08398069124448497,destabilizing
+SRSF9,TTC28,0.18746162151215834,destabilizing
+SRSF9,SBNO1,0.12785904422187203,destabilizing
+SRSF9,RIMS2,0.17224104083308658,destabilizing
+SRSF9,IGF1R,0.10090478546827994,destabilizing
+SRSF9,TRIO,0.09519944155154232,destabilizing
+SRSF9,KCND2,0.08636987400272315,destabilizing
+SRSF9,BTBD9,0.20579346166776125,destabilizing
+SRSF9,CNGB1,0.27479434573403777,destabilizing
+SRSF9,FMN2,0.19997231023779188,destabilizing
+SRSF9,ENSG00000228222,0.3553694088273562,destabilizing
+SRSF9,ATXN1,0.10087098890772526,destabilizing
+SRSF9,SYN3,0.09735132469397043,destabilizing
+SRSF9,PRKN,0.2499978053766029,destabilizing
+SRSF9,RASA2,0.2677554436770194,destabilizing
+SRSF9,PPP1R12B,0.13601021820030984,destabilizing
+SRSF9,FRMD4A,0.18163566586316235,destabilizing
+SRSF9,CAMK1D,0.10185948090114269,destabilizing
+SRSF9,PARD3,0.08401040852057733,destabilizing
+SRSF9,SEMA6D,0.23558137840781124,destabilizing
+SRSF9,WIPF2,0.2359937445394635,destabilizing
+SRSF9,DLEU1,0.2999230972099433,destabilizing
+SRSF9,TSHZ2,0.13578874678146388,destabilizing
+SRSF9,MED13L,0.14957761379402343,destabilizing
+SRSF9,AFF3,0.06025768683093051,destabilizing
+SRSF9,KAZN,0.22557570425608933,destabilizing
+SRSF9,KANSL1,0.1682774926546682,destabilizing
+SRSF9,FRMD5,0.20280660952917737,destabilizing
+SRSF9,LINC00174,0.2312636153229849,destabilizing
+SRSF9,PPM1E,0.2031406398136056,destabilizing
+SRSF9,ARL3,0.16701187493208886,destabilizing
+SRSF9,MBD5,0.21343790808946914,destabilizing
+SRSF9,ELAVL3,0.2252881790034311,destabilizing
+SRSF9,SLIT2,0.2936767738277503,destabilizing
+SRSF9,SLC8A1,0.08036965152997838,destabilizing
+SRSF9,CLASP1,0.17637699013248634,destabilizing
+SRSF9,DOCK4,0.057890600475460983,destabilizing
+SRSF9,UNC5C,0.22409222939127776,destabilizing
+SRSF9,CACNA2D3,-0.09740992953425069,stabilizing
+SRSF9,RC3H1,0.147203001979993,destabilizing
+SRSF9,NEGR1,0.2593300048589185,destabilizing
+SRSF9,ENOX1,0.3212194069247163,destabilizing
+SRSF9,SCUBE1,0.13051148765012083,destabilizing
+SRSF9,GPHN,0.14776102050533257,destabilizing
+SRSF9,NAV3,0.2483175072357455,destabilizing
+SRSF9,EBF1,0.10797637484938277,destabilizing
+SRSF9,TOMM22,0.283914396155244,destabilizing
+SRSF9,MBNL2,0.13192481614417814,destabilizing
+SRSF9,ANKFN1,0.10446867262999306,destabilizing
+SRSF9,MAGI2,0.12186530313642356,destabilizing
+SRSF9,LSAMP,0.1542317534400521,destabilizing
+SRSF9,AKAP6,0.25007039601952896,destabilizing
+SRSF9,TMED2,0.17769620064681915,destabilizing
+SRSF9,ZBTB20,0.21408494474429166,destabilizing
+SRSF9,GRIK2,0.20931553671431244,destabilizing
+SRSF9,SOX5,0.17543022862460145,destabilizing
+SRSF9,LRRC37A3,0.3309883657680359,destabilizing
+SRSF9,TMEM132C,0.09452996257848026,destabilizing
+SRSF9,EYS,0.1687973888124104,destabilizing
+SRSF9,ARID1B,0.17047573096769392,destabilizing
+SRSF9,PRKCE,0.16253352309190922,destabilizing
+SRSF9,RBFOX1,-0.09689136531653589,stabilizing
+SRSF9,SDK1,0.13579590668439628,destabilizing
+SRSF9,NRG1,0.10798976720946045,destabilizing
+SRSF9,RORA,0.08182857155509396,destabilizing
+SRSF9,MLLT3,0.3436787683593404,destabilizing
+SRSF9,FMN1,0.1767827603906393,destabilizing
+SRSF9,ADGRB3,0.14332586873543957,destabilizing
+SRSF9,ROBO1,0.18003991858697643,destabilizing
+SRSF9,SYPL1,0.14577649451172425,destabilizing
+SRSF9,PTPRD,0.20596440053800788,destabilizing
+SRSF9,FAM155A,0.24508213423521136,destabilizing
+SRSF9,LARP1B,0.20780543906379326,destabilizing
+SRSF10,TRERF1,0.11297199611402624,destabilizing
+SRSF10,SORCS1,0.10458543667565219,destabilizing
+SRSF10,PDE3A,0.12394252710460782,destabilizing
+SRSF10,UNC79,0.14549380196828213,destabilizing
+SRSF10,DOC2B,0.1052857934258526,destabilizing
+SRSF10,TMTC2,0.14361600609595518,destabilizing
+SRSF10,KALRN,0.10372831379029969,destabilizing
+SRSF10,CHD1,0.0704435188872733,destabilizing
+SRSF10,UBE2E2,0.07686765248476135,destabilizing
+SRSF10,PPARD,0.11765150380352805,destabilizing
+SRSF10,RYR2,0.12992141968745352,destabilizing
+SRSF10,MTMR7,0.16723659317312628,destabilizing
+SRSF10,EIF4E,0.1525656757815876,destabilizing
+SRSF10,EPB41L4B,0.07196831245843752,destabilizing
+SRSF10,CACNA1B,0.07855214366038499,destabilizing
+SRSF10,LRRTM4,0.07919321016905569,destabilizing
+SRSF10,SIRPA,0.10294597770333153,destabilizing
+SRSF10,PTEN,0.08363652026129649,destabilizing
+SRSF10,FRY,0.17526409466252346,destabilizing
+SRSF10,MACROD2,0.14477661697901686,destabilizing
+SRSF10,SHANK2,0.16704175827343026,destabilizing
+SRSF10,CDK12,0.22884801955312056,destabilizing
+SRSF10,RFX7,0.15991568760287714,destabilizing
+SRSF10,MPHOSPH8,0.12330353434044461,destabilizing
+SRSF10,DIP2C,0.08192412801200123,destabilizing
+SRSF10,UBR3,0.07974222499466281,destabilizing
+SRSF10,DLG2,0.12060045553874044,destabilizing
+SRSF10,CHST12,0.24081751588397365,destabilizing
+SRSF10,EML5,0.1573663338176147,destabilizing
+SRSF10,CENPP,0.25302538765908317,destabilizing
+SRSF10,PSME4,0.1263757227120316,destabilizing
+SRSF10,TMEM106B,0.13636239857986937,destabilizing
+SRSF10,EPHA5,0.12165980641101337,destabilizing
+SRSF10,KCNB2,0.1785982370711491,destabilizing
+SRSF10,ZNF83,0.12591215106804374,destabilizing
+SRSF10,SOX6,0.08722138299226831,destabilizing
+SRSF10,ZNF521,0.12497197160686362,destabilizing
+SRSF10,NOVA1,0.17071732522013616,destabilizing
+SRSF10,CCNY,0.1366814221082207,destabilizing
+SRSF10,ARIH1,0.09395586280012931,destabilizing
+SRSF10,EPB41L5,0.07427059800463275,destabilizing
+SRSF10,GPR158,0.12968454229578674,destabilizing
+SRSF10,NCOA2,0.09479219955625458,destabilizing
+SRSF10,ALK,0.1977198204310978,destabilizing
+SRSF10,ACACA,0.05985475710088376,destabilizing
+SRSF10,IFT172,0.13143555634781431,destabilizing
+SRSF10,CCNT1,0.0781289368224618,destabilizing
+SRSF10,DTWD2,0.21751602031715472,destabilizing
+SRSF10,SIK3,0.14205658342003197,destabilizing
+SRSF10,CPEB3,0.13411096333090602,destabilizing
+SRSF10,XKR6,0.14624663165725565,destabilizing
+SRSF10,RMND5A,0.05515062221816588,destabilizing
+SRSF10,CADPS,0.07115904332758503,destabilizing
+SRSF10,TCF20,0.12014247883298179,destabilizing
+SRSF10,CDKAL1,0.08347078224361937,destabilizing
+SRSF10,DGKI,0.11078893623774436,destabilizing
+SRSF10,EXOC6B,0.1632030594427515,destabilizing
+SRSF10,MAGI3,0.1623397405825776,destabilizing
+SRSF10,INPP4B,0.11848727667716699,destabilizing
+SRSF10,PTPRS,0.12397294133449453,destabilizing
+SRSF10,SPDYE3,0.09294432210425259,destabilizing
+SRSF10,TMEM178B,0.06706250207748564,destabilizing
+SRSF10,DMD,0.17556640861302647,destabilizing
+SRSF10,EIF4G3,0.056754902162876035,destabilizing
+SRSF10,MCU,0.1262816604858261,destabilizing
+SRSF10,SSH2,0.1118787471764637,destabilizing
+SRSF10,DOCK3,0.16284059164728426,destabilizing
+SRSF10,HS6ST3,0.1147131913374909,destabilizing
+SRSF10,LPP,0.10850121177462661,destabilizing
+SRSF10,STAG1,0.10202658423357595,destabilizing
+SRSF10,CAPZA2,0.1388262009263301,destabilizing
+SRSF10,PHACTR1,0.07413470671884684,destabilizing
+SRSF10,UBE2R2,0.1200704168035481,destabilizing
+SRSF10,GTF2IRD1,0.09750404681030894,destabilizing
+SRSF10,TTC28,0.08250829122752754,destabilizing
+SRSF10,SBNO1,0.06817767954134671,destabilizing
+SRSF10,RIMS2,0.08757557876955017,destabilizing
+SRSF10,BTBD9,0.119862662032712,destabilizing
+SRSF10,CNGB1,0.1614664254595871,destabilizing
+SRSF10,FMN2,0.09826791619267072,destabilizing
+SRSF10,ENSG00000228222,0.20923024554361822,destabilizing
+SRSF10,SYN3,0.05098633079484978,destabilizing
+SRSF10,PRKN,0.1653013156543998,destabilizing
+SRSF10,RASA2,0.14073171646900923,destabilizing
+SRSF10,PPP1R12B,0.07049229637510633,destabilizing
+SRSF10,FRMD4A,0.09960811314470827,destabilizing
+SRSF10,SEMA6D,0.11228533422884128,destabilizing
+SRSF10,WIPF2,0.14024479412770963,destabilizing
+SRSF10,DLEU1,0.16787611776716377,destabilizing
+SRSF10,TSHZ2,0.07925192281724673,destabilizing
+SRSF10,MED13L,0.07196181665870467,destabilizing
+SRSF10,KAZN,0.10097889085273996,destabilizing
+SRSF10,KANSL1,0.07708026409578736,destabilizing
+SRSF10,FRMD5,0.12424115302687777,destabilizing
+SRSF10,LINC00174,0.129748560743972,destabilizing
+SRSF10,PPM1E,0.09637597796824356,destabilizing
+SRSF10,ARL3,0.08990484958514604,destabilizing
+SRSF10,MBD5,0.07961596795717035,destabilizing
+SRSF10,ELAVL3,0.1293601866462413,destabilizing
+SRSF10,SLIT2,0.17165982119809509,destabilizing
+SRSF10,CLASP1,0.09413553436862582,destabilizing
+SRSF10,UNC5C,0.13089558546947846,destabilizing
+SRSF10,CACNA2D3,-0.05502833623675736,stabilizing
+SRSF10,NEGR1,0.12374091310840632,destabilizing
+SRSF10,ENOX1,0.19422047531407255,destabilizing
+SRSF10,GPHN,0.07934926464563884,destabilizing
+SRSF10,NAV3,0.13996262549489288,destabilizing
+SRSF10,TOMM22,0.16171350210532473,destabilizing
+SRSF10,ANKFN1,0.05496355668136821,destabilizing
+SRSF10,MAGI2,0.054684538679146695,destabilizing
+SRSF10,LSAMP,0.07761527831819946,destabilizing
+SRSF10,AKAP6,0.11969921818406307,destabilizing
+SRSF10,TMED2,0.08451898330362728,destabilizing
+SRSF10,ZBTB20,0.12324211744831964,destabilizing
+SRSF10,GRIK2,0.10525018500999832,destabilizing
+SRSF10,SOX5,0.0764916973530279,destabilizing
+SRSF10,LRRC37A3,0.1626785669433459,destabilizing
+SRSF10,EYS,0.09980981547417325,destabilizing
+SRSF10,ARID1B,0.07201149525014597,destabilizing
+SRSF10,PRKCE,0.08688827572547737,destabilizing
+SRSF10,RBFOX1,-0.07927151852191987,stabilizing
+SRSF10,MLLT3,0.19645623225722753,destabilizing
+SRSF10,FMN1,0.06500938053006967,destabilizing
+SRSF10,ADGRB3,0.05922479993335958,destabilizing
+SRSF10,ROBO1,0.08459535208970069,destabilizing
+SRSF10,SYPL1,0.08058860502612215,destabilizing
+SRSF10,PTPRD,0.11140302527901336,destabilizing
+SRSF10,FAM155A,0.12410001330331358,destabilizing
+SRSF10,LARP1B,0.1130301827486705,destabilizing
+SRSF11,TRERF1,0.17968510589046469,destabilizing
+SRSF11,SORCS1,0.14501939119152893,destabilizing
+SRSF11,NCOA1,0.05627225372047838,destabilizing
+SRSF11,COPA,0.06266942115661986,destabilizing
+SRSF11,FCHSD2,0.09236366911213398,destabilizing
+SRSF11,PDE3A,0.19515172539673625,destabilizing
+SRSF11,UNC79,0.2004969657431988,destabilizing
+SRSF11,DOC2B,0.1207671588750881,destabilizing
+SRSF11,TMTC2,0.1624514105122122,destabilizing
+SRSF11,KALRN,0.14079725280066135,destabilizing
+SRSF11,CHD1,0.10388290748171763,destabilizing
+SRSF11,UBE2E2,0.07062922919472026,destabilizing
+SRSF11,PPARD,0.09227436185795937,destabilizing
+SRSF11,BRAF,0.05829555455411859,destabilizing
+SRSF11,RYR2,0.14449966087933516,destabilizing
+SRSF11,MTMR7,0.17400327841232854,destabilizing
+SRSF11,EIF4E,0.1897807100426119,destabilizing
+SRSF11,SOX11,0.06734366691065007,destabilizing
+SRSF11,EPB41L4B,0.130736592582858,destabilizing
+SRSF11,CACNA1B,0.12067060328328923,destabilizing
+SRSF11,TBC1D5,0.060798850443879435,destabilizing
+SRSF11,LRRTM4,0.13323315188675763,destabilizing
+SRSF11,SIRPA,0.16028350371127184,destabilizing
+SRSF11,PTEN,0.1339012480754207,destabilizing
+SRSF11,FRY,0.19372180516836324,destabilizing
+SRSF11,MACROD2,0.146374732450215,destabilizing
+SRSF11,SHANK2,0.21588932439752131,destabilizing
+SRSF11,CDK12,0.2510499831039094,destabilizing
+SRSF11,RFX7,0.1778527405375971,destabilizing
+SRSF11,UBR5,0.07336001245689538,destabilizing
+SRSF11,JARID2,0.09547298989615685,destabilizing
+SRSF11,MPHOSPH8,0.15469899383390706,destabilizing
+SRSF11,DIP2C,0.1279490632409551,destabilizing
+SRSF11,ZNF423,0.058521485820561985,destabilizing
+SRSF11,UBR3,0.134476080899526,destabilizing
+SRSF11,MGAT5,0.08021487136880105,destabilizing
+SRSF11,DLG2,0.09431740052680547,destabilizing
+SRSF11,CHST12,0.26703614469973513,destabilizing
+SRSF11,EML5,0.1857110866267536,destabilizing
+SRSF11,CENPP,0.20460643388498792,destabilizing
+SRSF11,PSME4,0.1789611750814506,destabilizing
+SRSF11,TMEM106B,0.21233747502162265,destabilizing
+SRSF11,EPHA5,0.1305857388879252,destabilizing
+SRSF11,KCNB2,0.170162821880757,destabilizing
+SRSF11,ZNF83,0.11947245213480244,destabilizing
+SRSF11,SOX6,0.10180913303940688,destabilizing
+SRSF11,ZNF521,0.15523300958617242,destabilizing
+SRSF11,PLEKHA5,0.10148323005330721,destabilizing
+SRSF11,NOVA1,0.1742158895265404,destabilizing
+SRSF11,CCNY,0.14924109796753116,destabilizing
+SRSF11,ARIH1,0.104076192112288,destabilizing
+SRSF11,FAM171B,0.0542334400280736,destabilizing
+SRSF11,EPB41L5,0.11673760268753572,destabilizing
+SRSF11,GPR158,0.16224023267011295,destabilizing
+SRSF11,NCOA2,0.1351034776664899,destabilizing
+SRSF11,PRKCB,0.05404824951309738,destabilizing
+SRSF11,MARCKS,0.05098622912302044,destabilizing
+SRSF11,ALK,0.16420264129393355,destabilizing
+SRSF11,ACACA,0.06572936423180877,destabilizing
+SRSF11,IFT172,0.15575879301940834,destabilizing
+SRSF11,CCNT1,0.10329014857030691,destabilizing
+SRSF11,DTWD2,0.23602829006321105,destabilizing
+SRSF11,SIK3,0.11941027390585977,destabilizing
+SRSF11,CPEB3,0.231084139839797,destabilizing
+SRSF11,CADM2,0.08970514513003494,destabilizing
+SRSF11,XKR6,0.18733970652293105,destabilizing
+SRSF11,RMND5A,0.06202405319750642,destabilizing
+SRSF11,CADPS,0.08302201309538064,destabilizing
+SRSF11,TCF20,0.15284568614016858,destabilizing
+SRSF11,CDKAL1,0.09595673170641404,destabilizing
+SRSF11,DGKI,0.1285427171102654,destabilizing
+SRSF11,EXOC6B,0.20761282554006216,destabilizing
+SRSF11,MAGI3,0.1778526576772331,destabilizing
+SRSF11,SBF2,0.07278500484706141,destabilizing
+SRSF11,INPP4B,0.15412932030025359,destabilizing
+SRSF11,ERC1,0.07095103325738135,destabilizing
+SRSF11,PTPRS,0.21629751602487726,destabilizing
+SRSF11,CBFA2T2,0.0819437521098121,destabilizing
+SRSF11,SPDYE3,0.14490125458836445,destabilizing
+SRSF11,TMEM178B,0.07483419499925133,destabilizing
+SRSF11,DMD,0.24341949588705972,destabilizing
+SRSF11,EIF4G3,0.05793164845054757,destabilizing
+SRSF11,MCU,0.14450441939142564,destabilizing
+SRSF11,SSH2,0.14317017311178798,destabilizing
+SRSF11,DOCK3,0.22253786614242763,destabilizing
+SRSF11,HS6ST3,0.1949963603480445,destabilizing
+SRSF11,LPP,0.20003749755008254,destabilizing
+SRSF11,STAG1,0.13950183364286897,destabilizing
+SRSF11,CAPZA2,0.1462658334239695,destabilizing
+SRSF11,ADGRL3,0.08887273414468073,destabilizing
+SRSF11,PHACTR1,0.078093626605437,destabilizing
+SRSF11,UBE2R2,0.1739864596653099,destabilizing
+SRSF11,GTF2IRD1,0.13495883896924396,destabilizing
+SRSF11,CCBE1,0.06292185497196,destabilizing
+SRSF11,TTC28,0.13311067159190448,destabilizing
+SRSF11,SBNO1,0.08138351161477075,destabilizing
+SRSF11,RIMS2,0.08223649986032003,destabilizing
+SRSF11,KCND2,0.05984516598308169,destabilizing
+SRSF11,BTBD9,0.1721892694102848,destabilizing
+SRSF11,CNGB1,0.1923500536623006,destabilizing
+SRSF11,FMN2,0.11818744685069502,destabilizing
+SRSF11,ENSG00000228222,0.2517050959484158,destabilizing
+SRSF11,PRKN,0.228354498373988,destabilizing
+SRSF11,RASA2,0.18984417140361187,destabilizing
+SRSF11,PPP1R12B,0.09506936102619262,destabilizing
+SRSF11,FRMD4A,0.11046377854485771,destabilizing
+SRSF11,SEMA6D,0.11296955629892663,destabilizing
+SRSF11,WIPF2,0.1812506315899293,destabilizing
+SRSF11,DLEU1,0.182945499040325,destabilizing
+SRSF11,TSHZ2,0.07950524439756912,destabilizing
+SRSF11,MED13L,0.08070821712128741,destabilizing
+SRSF11,AFF3,0.05519590903760549,destabilizing
+SRSF11,KAZN,0.1429020563562697,destabilizing
+SRSF11,KANSL1,0.08105078972615815,destabilizing
+SRSF11,FRMD5,0.14031423866059312,destabilizing
+SRSF11,LINC00174,0.15831392284384263,destabilizing
+SRSF11,PPM1E,0.13819101583760193,destabilizing
+SRSF11,ARL3,0.10896499597046765,destabilizing
+SRSF11,MBD5,0.12608808189449347,destabilizing
+SRSF11,ELAVL3,0.154498596334443,destabilizing
+SRSF11,SLIT2,0.2168677421564966,destabilizing
+SRSF11,CLASP1,0.10093105706179324,destabilizing
+SRSF11,UNC5C,0.13665782939534757,destabilizing
+SRSF11,CACNA2D3,-0.07441965241094636,stabilizing
+SRSF11,RC3H1,0.11448714351389497,destabilizing
+SRSF11,NEGR1,0.16263624596869075,destabilizing
+SRSF11,ENOX1,0.2563094768272628,destabilizing
+SRSF11,SCUBE1,0.10072462694549386,destabilizing
+SRSF11,GPHN,0.1069597040586975,destabilizing
+SRSF11,NAV3,0.1872774215081286,destabilizing
+SRSF11,EBF1,0.06357904678783124,destabilizing
+SRSF11,TOMM22,0.20551455328989396,destabilizing
+SRSF11,ANKFN1,0.06711280583822128,destabilizing
+SRSF11,MAGI2,0.06314648684196965,destabilizing
+SRSF11,LSAMP,0.11129063028091386,destabilizing
+SRSF11,AKAP6,0.16024907284351514,destabilizing
+SRSF11,TMED2,0.1210067143856313,destabilizing
+SRSF11,ZBTB20,0.13331357741853359,destabilizing
+SRSF11,GRIK2,0.14574828422165345,destabilizing
+SRSF11,SOX5,0.08356125225266176,destabilizing
+SRSF11,LRRC37A3,0.19459727122099243,destabilizing
+SRSF11,TMEM132C,0.06505638409775254,destabilizing
+SRSF11,EYS,0.12913035174081244,destabilizing
+SRSF11,ARID1B,0.07986678924863189,destabilizing
+SRSF11,PRKCE,0.09977445664528797,destabilizing
+SRSF11,RBFOX1,-0.0981200624926402,stabilizing
+SRSF11,SDK1,0.08357776122965141,destabilizing
+SRSF11,NRG1,0.06075821711491712,destabilizing
+SRSF11,MLLT3,0.24546306120552297,destabilizing
+SRSF11,FMN1,0.061965334595063544,destabilizing
+SRSF11,ADGRB3,0.08395721476175198,destabilizing
+SRSF11,ROBO1,0.1174776162298886,destabilizing
+SRSF11,SYPL1,0.07783297528344194,destabilizing
+SRSF11,PTPRD,0.14238928721627536,destabilizing
+SRSF11,FAM155A,0.17481536908447365,destabilizing
+SRSF11,LARP1B,0.1673216320822212,destabilizing
+TRA2A,TRERF1,0.13932595280258359,destabilizing
+TRA2A,SORCS1,0.09680198863971348,destabilizing
+TRA2A,PDE3A,0.15168005534760007,destabilizing
+TRA2A,UNC79,0.13660958239946216,destabilizing
+TRA2A,DOC2B,0.09564759559417003,destabilizing
+TRA2A,TMTC2,0.11479157698731364,destabilizing
+TRA2A,KALRN,0.08528126308728833,destabilizing
+TRA2A,CHD1,0.06330195427239134,destabilizing
+TRA2A,UBE2E2,0.0648700704666348,destabilizing
+TRA2A,PPARD,0.08406955812816301,destabilizing
+TRA2A,RYR2,0.11524206104991759,destabilizing
+TRA2A,MTMR7,0.1314578408627951,destabilizing
+TRA2A,SOX11,0.07503280949980319,destabilizing
+TRA2A,CACNA1B,0.07995674312283746,destabilizing
+TRA2A,LRRTM4,0.07820085579942881,destabilizing
+TRA2A,SIRPA,0.12439193647540335,destabilizing
+TRA2A,PTEN,0.08179038441662001,destabilizing
+TRA2A,FRY,0.12198425228627509,destabilizing
+TRA2A,MACROD2,0.0994116683106726,destabilizing
+TRA2A,SHANK2,0.16408709162669768,destabilizing
+TRA2A,CDK12,0.14522819064439144,destabilizing
+TRA2A,RFX7,0.13479712826127982,destabilizing
+TRA2A,UBR5,0.06247300595320576,destabilizing
+TRA2A,JARID2,0.05695916389082925,destabilizing
+TRA2A,MPHOSPH8,0.10559050231918302,destabilizing
+TRA2A,DIP2C,0.08028089905297557,destabilizing
+TRA2A,UBR3,0.1107965959093383,destabilizing
+TRA2A,DLG2,0.08023760092838647,destabilizing
+TRA2A,CHST12,0.2029030669888957,destabilizing
+TRA2A,EML5,0.12637861193907649,destabilizing
+TRA2A,CENPP,0.1482175634292941,destabilizing
+TRA2A,PSME4,0.10121479090761794,destabilizing
+TRA2A,TMEM106B,0.12220451973471218,destabilizing
+TRA2A,EPHA5,0.09136335158838996,destabilizing
+TRA2A,KCNB2,0.15177833064643861,destabilizing
+TRA2A,ZNF83,0.08930104741566576,destabilizing
+TRA2A,SOX6,0.06705377641617097,destabilizing
+TRA2A,ZNF521,0.07850525468279033,destabilizing
+TRA2A,PLEKHA5,0.08194366328851324,destabilizing
+TRA2A,NOVA1,0.16131158782257102,destabilizing
+TRA2A,CCNY,0.116678142755187,destabilizing
+TRA2A,ARIH1,0.08766735798450216,destabilizing
+TRA2A,EPB41L5,0.0752498922972198,destabilizing
+TRA2A,GPR158,0.11258924172812108,destabilizing
+TRA2A,NCOA2,0.06925763076920055,destabilizing
+TRA2A,ALK,0.1208580373849253,destabilizing
+TRA2A,ACACA,0.0869627576433479,destabilizing
+TRA2A,IFT172,0.08778511941588259,destabilizing
+TRA2A,CCNT1,0.05528954626595372,destabilizing
+TRA2A,SIK3,0.09958474632586489,destabilizing
+TRA2A,CPEB3,0.1435053354195212,destabilizing
+TRA2A,XKR6,0.1314936246658197,destabilizing
+TRA2A,CADPS,0.07211739579100224,destabilizing
+TRA2A,TCF20,0.10661372117847136,destabilizing
+TRA2A,CDKAL1,0.08675306637037829,destabilizing
+TRA2A,DGKI,0.0806576948701804,destabilizing
+TRA2A,EXOC6B,0.16658734085064783,destabilizing
+TRA2A,MAGI3,0.13198067491013268,destabilizing
+TRA2A,SBF2,0.06313919830255228,destabilizing
+TRA2A,INPP4B,0.11688946464268728,destabilizing
+TRA2A,SPDYE3,0.10678571021032307,destabilizing
+TRA2A,DMD,0.18453160372890529,destabilizing
+TRA2A,MCU,0.11780275760968217,destabilizing
+TRA2A,SSH2,0.08236327758754472,destabilizing
+TRA2A,DOCK3,0.14063222296093528,destabilizing
+TRA2A,HS6ST3,0.09573030767984754,destabilizing
+TRA2A,LPP,0.11709534811494739,destabilizing
+TRA2A,STAG1,0.10378836830992332,destabilizing
+TRA2A,CAPZA2,0.07791112108168746,destabilizing
+TRA2A,ADGRL3,0.05993147764136796,destabilizing
+TRA2A,PHACTR1,0.06529427469604736,destabilizing
+TRA2A,UBE2R2,0.10266782846429699,destabilizing
+TRA2A,GTF2IRD1,0.12302179957602678,destabilizing
+TRA2A,CCBE1,0.052000438973069184,destabilizing
+TRA2A,TTC28,0.09495322285902885,destabilizing
+TRA2A,RIMS2,0.06552937732260926,destabilizing
+TRA2A,BTBD9,0.12441260396972437,destabilizing
+TRA2A,CNGB1,0.1282387330583066,destabilizing
+TRA2A,FMN2,0.10386894680147939,destabilizing
+TRA2A,ENSG00000228222,0.18958759219523688,destabilizing
+TRA2A,PRKN,0.14973072150461428,destabilizing
+TRA2A,RASA2,0.09268510511908712,destabilizing
+TRA2A,PPP1R12B,0.06492015844581954,destabilizing
+TRA2A,FRMD4A,0.0809177252623519,destabilizing
+TRA2A,SEMA6D,0.07598135118294634,destabilizing
+TRA2A,WIPF2,0.11846011602841075,destabilizing
+TRA2A,DLEU1,0.12772227933959998,destabilizing
+TRA2A,TSHZ2,0.06724459667639258,destabilizing
+TRA2A,MED13L,0.0768269559994957,destabilizing
+TRA2A,KAZN,0.08847642301552702,destabilizing
+TRA2A,FRMD5,0.10549342679388676,destabilizing
+TRA2A,LINC00174,0.07851757800483,destabilizing
+TRA2A,PPM1E,0.09652459930376496,destabilizing
+TRA2A,ARL3,0.0746377636074579,destabilizing
+TRA2A,MBD5,0.09175499425120062,destabilizing
+TRA2A,ELAVL3,0.09575937046953141,destabilizing
+TRA2A,SLIT2,0.1441308840895048,destabilizing
+TRA2A,CLASP1,0.07986980462473746,destabilizing
+TRA2A,UNC5C,0.09308813110492566,destabilizing
+TRA2A,CACNA2D3,-0.07465281553828616,stabilizing
+TRA2A,RC3H1,0.061479918526699734,destabilizing
+TRA2A,NEGR1,0.1506535735914935,destabilizing
+TRA2A,ENOX1,0.14601463636188888,destabilizing
+TRA2A,SCUBE1,0.07491319937063019,destabilizing
+TRA2A,GPHN,0.08606458988110448,destabilizing
+TRA2A,NAV3,0.13575079296332784,destabilizing
+TRA2A,TOMM22,0.12909871232543482,destabilizing
+TRA2A,MAGI2,0.06394511099809563,destabilizing
+TRA2A,LSAMP,0.0670575883990029,destabilizing
+TRA2A,AKAP6,0.10725060498868488,destabilizing
+TRA2A,ZBTB20,0.10308325213474974,destabilizing
+TRA2A,GRIK2,0.0971892001747943,destabilizing
+TRA2A,LRRC37A3,0.1515835647998288,destabilizing
+TRA2A,EYS,0.07460109123353315,destabilizing
+TRA2A,ARID1B,0.0622109785278929,destabilizing
+TRA2A,PRKCE,0.06944805737394963,destabilizing
+TRA2A,RBFOX1,-0.09325444393354357,stabilizing
+TRA2A,MLLT3,0.16294683720777886,destabilizing
+TRA2A,ADGRB3,0.06194240524085506,destabilizing
+TRA2A,ROBO1,0.11194627351188498,destabilizing
+TRA2A,SYPL1,0.06552144030105057,destabilizing
+TRA2A,PTPRD,0.08313615001829601,destabilizing
+TRA2A,FAM155A,0.11485946567354952,destabilizing
+TRA2A,LARP1B,0.12938202049146294,destabilizing
+TRA2B,TRERF1,0.13135429283626537,destabilizing
+TRA2B,SORCS1,0.11805415631205637,destabilizing
+TRA2B,PDE3A,0.1018676610522148,destabilizing
+TRA2B,UNC79,0.17390828934392594,destabilizing
+TRA2B,DOC2B,0.10307197566397011,destabilizing
+TRA2B,TMTC2,0.12863474295581565,destabilizing
+TRA2B,CHD1,0.06497771863610631,destabilizing
+TRA2B,UBE2E2,0.07869071926207681,destabilizing
+TRA2B,PPARD,0.11754016228629591,destabilizing
+TRA2B,TOX,0.07622788109263114,destabilizing
+TRA2B,BRAF,0.05320429901650464,destabilizing
+TRA2B,RYR2,0.12071094648017545,destabilizing
+TRA2B,MTMR7,0.14656252590558258,destabilizing
+TRA2B,EIF4E,0.1385991726032709,destabilizing
+TRA2B,CACNA1B,0.07753598304784905,destabilizing
+TRA2B,LRRTM4,0.09390846941233805,destabilizing
+TRA2B,SIRPA,0.10191475184320813,destabilizing
+TRA2B,PTEN,0.10465886721634582,destabilizing
+TRA2B,FRY,0.15451867999656266,destabilizing
+TRA2B,MACROD2,0.13153890896436107,destabilizing
+TRA2B,SHANK2,0.17855369289204062,destabilizing
+TRA2B,CDK12,0.1884658348149563,destabilizing
+TRA2B,RFX7,0.1237382748355551,destabilizing
+TRA2B,JARID2,0.060896025772729304,destabilizing
+TRA2B,MPHOSPH8,0.11692220909898175,destabilizing
+TRA2B,DIP2C,0.09322703034198118,destabilizing
+TRA2B,UBR3,0.07584489156939062,destabilizing
+TRA2B,DLG2,0.08520686516428932,destabilizing
+TRA2B,CHST12,0.22301224642857254,destabilizing
+TRA2B,EML5,0.16091073863164235,destabilizing
+TRA2B,CENPP,0.27126864755390356,destabilizing
+TRA2B,PSME4,0.13441228155213936,destabilizing
+TRA2B,TMEM106B,0.11626725951527948,destabilizing
+TRA2B,EPHA5,0.10494311397669201,destabilizing
+TRA2B,KCNB2,0.16639665970370837,destabilizing
+TRA2B,ZNF83,0.08747481774807943,destabilizing
+TRA2B,SOX6,0.058901262574914105,destabilizing
+TRA2B,ZNF521,0.11214797141126967,destabilizing
+TRA2B,PLEKHA5,0.06476069579201234,destabilizing
+TRA2B,NOVA1,0.14568101229581246,destabilizing
+TRA2B,CCNY,0.1299222142281019,destabilizing
+TRA2B,ARIH1,0.09726064224214187,destabilizing
+TRA2B,EPB41L5,0.08903745496695158,destabilizing
+TRA2B,GPR158,0.10319692920705062,destabilizing
+TRA2B,ALK,0.2033445640492507,destabilizing
+TRA2B,IFT172,0.13357401790046006,destabilizing
+TRA2B,CCNT1,0.08934876095114512,destabilizing
+TRA2B,DTWD2,0.22224623237885544,destabilizing
+TRA2B,SIK3,0.15612665676213203,destabilizing
+TRA2B,CPEB3,0.11771530081141651,destabilizing
+TRA2B,XKR6,0.14775526593036917,destabilizing
+TRA2B,CADPS,0.07301451698387658,destabilizing
+TRA2B,TCF20,0.1345679030093865,destabilizing
+TRA2B,CDKAL1,0.07407776071896878,destabilizing
+TRA2B,DGKI,0.07967350121840398,destabilizing
+TRA2B,EXOC6B,0.15634294866291942,destabilizing
+TRA2B,MAGI3,0.11868528683945816,destabilizing
+TRA2B,SBF2,0.05722737782810539,destabilizing
+TRA2B,INPP4B,0.08789690931822403,destabilizing
+TRA2B,SPDYE3,0.07487752302573107,destabilizing
+TRA2B,DMD,0.19296717070818592,destabilizing
+TRA2B,MCU,0.13597697080321108,destabilizing
+TRA2B,SSH2,0.10988606086929141,destabilizing
+TRA2B,DOCK3,0.1382718993234176,destabilizing
+TRA2B,HS6ST3,0.09757789382525599,destabilizing
+TRA2B,LPP,0.13948096736483223,destabilizing
+TRA2B,STAG1,0.08204269986330441,destabilizing
+TRA2B,CAPZA2,0.1378234971261477,destabilizing
+TRA2B,PHACTR1,0.0689459322434664,destabilizing
+TRA2B,UBE2R2,0.11906079114370173,destabilizing
+TRA2B,GTF2IRD1,0.07961077906988095,destabilizing
+TRA2B,TTC28,0.09550296600992077,destabilizing
+TRA2B,SBNO1,0.05753490409594311,destabilizing
+TRA2B,RIMS2,0.07628491301475822,destabilizing
+TRA2B,BTBD9,0.11662943090959346,destabilizing
+TRA2B,CNGB1,0.15165171675819059,destabilizing
+TRA2B,FMN2,0.08939567453964554,destabilizing
+TRA2B,ENSG00000228222,0.19950441672695804,destabilizing
+TRA2B,SYN3,0.06654927987920363,destabilizing
+TRA2B,PRKN,0.10978529553422949,destabilizing
+TRA2B,RASA2,0.12452141222853967,destabilizing
+TRA2B,PPP1R12B,0.0965454703203547,destabilizing
+TRA2B,FRMD4A,0.08846459161709361,destabilizing
+TRA2B,SEMA6D,0.09284037481382551,destabilizing
+TRA2B,WIPF2,0.1400960311141215,destabilizing
+TRA2B,DLEU1,0.1587384698231026,destabilizing
+TRA2B,TSHZ2,0.07805848756149877,destabilizing
+TRA2B,KAZN,0.07109934810271827,destabilizing
+TRA2B,KANSL1,0.06718813481620849,destabilizing
+TRA2B,FRMD5,0.09855718253148578,destabilizing
+TRA2B,LINC00174,0.1150633119419222,destabilizing
+TRA2B,ARL3,0.09517803430704878,destabilizing
+TRA2B,MBD5,0.08925558836242058,destabilizing
+TRA2B,ELAVL3,0.1291892100717485,destabilizing
+TRA2B,SLIT2,0.13082944128608376,destabilizing
+TRA2B,CLASP1,0.09795265753111104,destabilizing
+TRA2B,UNC5C,0.1049792077969774,destabilizing
+TRA2B,RC3H1,0.08182302178829369,destabilizing
+TRA2B,NEGR1,0.1342225858360474,destabilizing
+TRA2B,ENOX1,0.17014786048549554,destabilizing
+TRA2B,GPHN,0.08530617530822106,destabilizing
+TRA2B,NAV3,0.13492392315041019,destabilizing
+TRA2B,TOMM22,0.12019375863217491,destabilizing
+TRA2B,LSAMP,0.0743171380381186,destabilizing
+TRA2B,AKAP6,0.12382094736421817,destabilizing
+TRA2B,TMED2,0.06999899101843136,destabilizing
+TRA2B,ZBTB20,0.13982130443892754,destabilizing
+TRA2B,GRIK2,0.07536148300031803,destabilizing
+TRA2B,LRRC37A3,0.17601549210091738,destabilizing
+TRA2B,EYS,0.08007288791729325,destabilizing
+TRA2B,ARID1B,0.0831668009170054,destabilizing
+TRA2B,PRKCE,0.07010300691959906,destabilizing
+TRA2B,RBFOX1,-0.06463808177067834,stabilizing
+TRA2B,MLLT3,0.18768357012845924,destabilizing
+TRA2B,FMN1,0.06280859366010311,destabilizing
+TRA2B,ADGRB3,0.059649292861028005,destabilizing
+TRA2B,ROBO1,0.0732926075906604,destabilizing
+TRA2B,PTPRD,0.10155776230511526,destabilizing
+TRA2B,FAM155A,0.12126472376594918,destabilizing
+TRA2B,LARP1B,0.1163538443942822,destabilizing
+PTBP1,MACROD2,0.07854603660399304,destabilizing
+PTBP1,CDK12,0.1167378099049974,destabilizing
+PTBP1,CENPP,0.16593782822114095,destabilizing
+PTBP1,KCNB2,0.12044789526902101,destabilizing
+PTBP1,ALK,0.15951181185925878,destabilizing
+PTBP1,MCU,0.07622638509764161,destabilizing
+PTBP1,DOCK3,0.08821681766372583,destabilizing
+PTBP1,CAPZA2,0.06636761771772236,destabilizing
+PTBP1,PHACTR1,0.06462934976060399,destabilizing
+PTBP1,RASA2,0.07076667081717893,destabilizing
+PTBP1,WIPF2,0.0717801376100871,destabilizing
+PTBP1,MBD5,0.06193848411710692,destabilizing
+PTBP1,MLLT3,0.08843995909078843,destabilizing
+PTBP1,PTPRD,0.056544618799178874,destabilizing
+PTBP2,TRERF1,0.11163046053129538,destabilizing
+PTBP2,UNC79,0.10047553221655017,destabilizing
+PTBP2,TMTC2,0.10710232015023366,destabilizing
+PTBP2,KALRN,0.06969261881370893,destabilizing
+PTBP2,MTMR7,0.10608698161636763,destabilizing
+PTBP2,EIF4E,0.14815319041084551,destabilizing
+PTBP2,CACNA1B,0.07246998314142541,destabilizing
+PTBP2,LRRTM4,0.07221303702230795,destabilizing
+PTBP2,FRY,0.12045377775516346,destabilizing
+PTBP2,MACROD2,0.08792724426833896,destabilizing
+PTBP2,SHANK2,0.12017413382994038,destabilizing
+PTBP2,CDK12,0.11290048070105128,destabilizing
+PTBP2,RFX7,0.09713573967154833,destabilizing
+PTBP2,MPHOSPH8,0.09226968145649139,destabilizing
+PTBP2,DIP2C,0.07041890210512093,destabilizing
+PTBP2,DLG2,0.08861969992582842,destabilizing
+PTBP2,CHST12,0.1904187349113279,destabilizing
+PTBP2,EML5,0.12097890109305795,destabilizing
+PTBP2,CENPP,0.12571023931993988,destabilizing
+PTBP2,PSME4,0.07148382132624087,destabilizing
+PTBP2,TMEM106B,0.11084135665380512,destabilizing
+PTBP2,EPHA5,0.07866865759545552,destabilizing
+PTBP2,KCNB2,0.12151438356755197,destabilizing
+PTBP2,SOX6,0.06398821206917206,destabilizing
+PTBP2,ZNF521,0.08958191401736205,destabilizing
+PTBP2,PLEKHA5,0.06886160987933221,destabilizing
+PTBP2,ARIH1,0.06326809265124897,destabilizing
+PTBP2,GPR158,0.08464622751010605,destabilizing
+PTBP2,NCOA2,0.0710170243049859,destabilizing
+PTBP2,ALK,0.1274677317932301,destabilizing
+PTBP2,IFT172,0.0848270256317848,destabilizing
+PTBP2,DTWD2,0.1731116467250382,destabilizing
+PTBP2,SIK3,0.07837790930031582,destabilizing
+PTBP2,CPEB3,0.15027601265345156,destabilizing
+PTBP2,XKR6,0.12331833524924045,destabilizing
+PTBP2,EXOC6B,0.10339584935776495,destabilizing
+PTBP2,MAGI3,0.0919982590894658,destabilizing
+PTBP2,INPP4B,0.10347427822436983,destabilizing
+PTBP2,PTPRS,0.11838986101471413,destabilizing
+PTBP2,DMD,0.13979625446847133,destabilizing
+PTBP2,SSH2,0.07809668814296032,destabilizing
+PTBP2,DOCK3,0.10813784459451858,destabilizing
+PTBP2,HS6ST3,0.09387725801980606,destabilizing
+PTBP2,LPP,0.09064283936341795,destabilizing
+PTBP2,CAPZA2,0.10520674534153546,destabilizing
+PTBP2,PHACTR1,0.0652209410171937,destabilizing
+PTBP2,UBE2R2,0.08446095358887441,destabilizing
+PTBP2,GTF2IRD1,0.06281841048404181,destabilizing
+PTBP2,BTBD9,0.09209585331181736,destabilizing
+PTBP2,CNGB1,0.08160046128616515,destabilizing
+PTBP2,FMN2,0.07719775509255825,destabilizing
+PTBP2,ENSG00000228222,0.1537283704786739,destabilizing
+PTBP2,RASA2,0.10407975206725308,destabilizing
+PTBP2,FRMD4A,0.057726420750072095,destabilizing
+PTBP2,SEMA6D,0.09315481504586585,destabilizing
+PTBP2,WIPF2,0.1102742249484477,destabilizing
+PTBP2,DLEU1,0.15243564902843412,destabilizing
+PTBP2,FRMD5,0.0770143713373808,destabilizing
+PTBP2,LINC00174,0.08419030671222275,destabilizing
+PTBP2,PPM1E,0.0733850278730771,destabilizing
+PTBP2,MBD5,0.07867350362776955,destabilizing
+PTBP2,ELAVL3,0.08505639616411298,destabilizing
+PTBP2,SLIT2,0.10906942360040027,destabilizing
+PTBP2,CLASP1,0.0728824239974643,destabilizing
+PTBP2,UNC5C,0.09533795695275796,destabilizing
+PTBP2,NEGR1,0.10732058393763555,destabilizing
+PTBP2,ENOX1,0.13787013439570173,destabilizing
+PTBP2,GPHN,0.07060092705579546,destabilizing
+PTBP2,NAV3,0.11229296541536905,destabilizing
+PTBP2,TOMM22,0.08279669435354095,destabilizing
+PTBP2,LSAMP,0.06059879162195104,destabilizing
+PTBP2,AKAP6,0.068674644707069,destabilizing
+PTBP2,TMED2,0.08242781355839271,destabilizing
+PTBP2,ZBTB20,0.09947359861986126,destabilizing
+PTBP2,GRIK2,0.06898719207898434,destabilizing
+PTBP2,SOX5,0.0664629840807091,destabilizing
+PTBP2,LRRC37A3,0.14405748544980101,destabilizing
+PTBP2,EYS,0.06154006951236333,destabilizing
+PTBP2,ARID1B,0.05807344342656432,destabilizing
+PTBP2,MLLT3,0.12631054386212942,destabilizing
+PTBP2,ROBO1,0.08177860421791995,destabilizing
+PTBP2,SYPL1,0.058146491746619816,destabilizing
+PTBP2,PTPRD,0.06809130130879716,destabilizing
+PTBP2,LARP1B,0.09291824095187702,destabilizing
+PTBP3,SORCS1,0.057365824993070774,destabilizing
+PTBP3,PDE3A,0.0931046669830606,destabilizing
+PTBP3,DOC2B,0.0615108403698913,destabilizing
+PTBP3,TMTC2,0.07866388789183568,destabilizing
+PTBP3,CACNA1B,0.06726329664521959,destabilizing
+PTBP3,FRY,0.09300891709764741,destabilizing
+PTBP3,MACROD2,0.07104083066893253,destabilizing
+PTBP3,CDK12,0.10980900729302102,destabilizing
+PTBP3,MPHOSPH8,0.06371553297637565,destabilizing
+PTBP3,CHST12,0.12381438589030636,destabilizing
+PTBP3,PSME4,0.07284117975569464,destabilizing
+PTBP3,NOVA1,0.09458039761394925,destabilizing
+PTBP3,ALK,0.10352141821942519,destabilizing
+PTBP3,XKR6,0.07497973179217499,destabilizing
+PTBP3,DMD,0.09564386311612513,destabilizing
+PTBP3,PRKN,0.11212736537997463,destabilizing
+PTBP3,RASA2,0.07347561581052331,destabilizing
+PTBP3,ARL3,0.05796046244916986,destabilizing
+PTBP3,SLIT2,0.11117958701992856,destabilizing
+PTBP3,UNC5C,0.07273610784763851,destabilizing
+PTBP3,NEGR1,0.0778240874119686,destabilizing
+PTBP3,TOMM22,0.08163313658455838,destabilizing
+PTBP3,EYS,0.06114447529758208,destabilizing
+PTBP3,MLLT3,0.12682581252359051,destabilizing
+PTBP3,PTPRD,0.07241856620823377,destabilizing
+PTBP3,LARP1B,0.07790322632284535,destabilizing
+PCBP2,TRERF1,0.33825889634751194,destabilizing
+PCBP2,SORCS1,0.23276110233152372,destabilizing
+PCBP2,NCOA1,0.10877103278243079,destabilizing
+PCBP2,COPA,0.15089392532189574,destabilizing
+PCBP2,FCHSD2,0.16572067349032654,destabilizing
+PCBP2,PDE3A,0.3715492113314007,destabilizing
+PCBP2,UNC79,0.32942180458995024,destabilizing
+PCBP2,DOC2B,0.26794038882135984,destabilizing
+PCBP2,TMTC2,0.30450515118802135,destabilizing
+PCBP2,KALRN,0.2089963221442367,destabilizing
+PCBP2,CHD1,0.18914119083949382,destabilizing
+PCBP2,PAK3,0.09061083855468116,destabilizing
+PCBP2,UBE2E2,0.1696268802506454,destabilizing
+PCBP2,PPARD,0.15910249879570562,destabilizing
+PCBP2,TOX,0.1447383191638024,destabilizing
+PCBP2,BRAF,0.12010978838677225,destabilizing
+PCBP2,RYR2,0.28372506981144735,destabilizing
+PCBP2,ZNF609,0.05547721895899157,destabilizing
+PCBP2,MTMR7,0.32053475633286,destabilizing
+PCBP2,EIF4E,0.24256254798644244,destabilizing
+PCBP2,SOX11,0.10869456245172433,destabilizing
+PCBP2,EPB41L4B,0.22226767129175617,destabilizing
+PCBP2,CACNA1B,0.1939285156939767,destabilizing
+PCBP2,TBC1D5,0.1061092805786585,destabilizing
+PCBP2,LRRTM4,0.2295291910450458,destabilizing
+PCBP2,SIRPA,0.28742300180325114,destabilizing
+PCBP2,MAP4K3,0.07208346336938877,destabilizing
+PCBP2,PTEN,0.2183855885569604,destabilizing
+PCBP2,SPPL3,0.0693920337469748,destabilizing
+PCBP2,FRY,0.342345587393318,destabilizing
+PCBP2,RUNX1T1,0.0762814049877335,destabilizing
+PCBP2,MACROD2,0.2995573326192834,destabilizing
+PCBP2,FOXN3,0.1265256515673318,destabilizing
+PCBP2,SHANK2,0.3399546253940779,destabilizing
+PCBP2,CDK12,0.3955170309653351,destabilizing
+PCBP2,BMPR1B,0.05952513721099178,destabilizing
+PCBP2,RFX7,0.3108579139419819,destabilizing
+PCBP2,UBR5,0.17648078306290613,destabilizing
+PCBP2,JARID2,0.18473569668430148,destabilizing
+PCBP2,MPHOSPH8,0.23757323712474376,destabilizing
+PCBP2,DIP2C,0.21619720834193765,destabilizing
+PCBP2,ZNF423,0.11141077279263645,destabilizing
+PCBP2,UBR3,0.18437509354604517,destabilizing
+PCBP2,MGAT5,0.12901489266267252,destabilizing
+PCBP2,DLG2,0.23860490225862752,destabilizing
+PCBP2,CHST12,0.4460658415362501,destabilizing
+PCBP2,EML5,0.3596897728597079,destabilizing
+PCBP2,CENPP,0.2871567607638709,destabilizing
+PCBP2,PSME4,0.2980450935086771,destabilizing
+PCBP2,TMEM106B,0.32349870095513567,destabilizing
+PCBP2,RABGAP1L,0.05840402352942216,destabilizing
+PCBP2,EPHA5,0.255707511475132,destabilizing
+PCBP2,KCNB2,0.27232479692445843,destabilizing
+PCBP2,ZNF83,0.17776022851188153,destabilizing
+PCBP2,SOX6,0.18854049402609413,destabilizing
+PCBP2,ZNF521,0.253558294874855,destabilizing
+PCBP2,PLEKHA5,0.19554357280850934,destabilizing
+PCBP2,DTL,0.1021774325986292,destabilizing
+PCBP2,NOVA1,0.3060279043259974,destabilizing
+PCBP2,CCNY,0.28991408578873734,destabilizing
+PCBP2,ARIH1,0.23847222132197085,destabilizing
+PCBP2,FAM171B,0.0945925885861019,destabilizing
+PCBP2,EPB41L5,0.21629367273791325,destabilizing
+PCBP2,GPR158,0.3289213232594131,destabilizing
+PCBP2,NCOA2,0.24503250870675608,destabilizing
+PCBP2,PUM2,0.05349316193003392,destabilizing
+PCBP2,ALK,0.36026221467798936,destabilizing
+PCBP2,ACACA,0.14864981973705574,destabilizing
+PCBP2,ARHGAP26,0.13291026724582544,destabilizing
+PCBP2,CTNND2,0.1439092747518228,destabilizing
+PCBP2,IFT172,0.3075593902225913,destabilizing
+PCBP2,CCNT1,0.19530589544423138,destabilizing
+PCBP2,DTWD2,0.3680014923554945,destabilizing
+PCBP2,SIK3,0.24153106012394238,destabilizing
+PCBP2,CPEB3,0.33064671017591574,destabilizing
+PCBP2,CADM2,0.14108837354434714,destabilizing
+PCBP2,XKR6,0.324515893731633,destabilizing
+PCBP2,RMND5A,0.10607169083444236,destabilizing
+PCBP2,CADPS,0.18197517036062025,destabilizing
+PCBP2,FGF13,0.13586049715571197,destabilizing
+PCBP2,TCF20,0.34104544231205663,destabilizing
+PCBP2,CDKAL1,0.16659984058245816,destabilizing
+PCBP2,DGKI,0.24403994413093513,destabilizing
+PCBP2,EXOC6B,0.3596635728420781,destabilizing
+PCBP2,MAGI3,0.2835333222679454,destabilizing
+PCBP2,SBF2,0.1783110807881418,destabilizing
+PCBP2,INPP4B,0.27545572175499344,destabilizing
+PCBP2,ERC1,0.13928004639710967,destabilizing
+PCBP2,PTPRS,0.3221823991528656,destabilizing
+PCBP2,CBFA2T2,0.16700673357686127,destabilizing
+PCBP2,SPDYE3,0.23797122977342924,destabilizing
+PCBP2,TMEM178B,0.15481811108792798,destabilizing
+PCBP2,KMT2C,0.07105810220722461,destabilizing
+PCBP2,CACNA2D1,0.10594636253631497,destabilizing
+PCBP2,DMD,0.39509474046748805,destabilizing
+PCBP2,EIF4G3,0.12801514652493184,destabilizing
+PCBP2,MCU,0.31048602959419164,destabilizing
+PCBP2,SSH2,0.24653023113179043,destabilizing
+PCBP2,TCF12,0.08508091126482668,destabilizing
+PCBP2,DOCK3,0.31590431163470184,destabilizing
+PCBP2,HS6ST3,0.29370623822835495,destabilizing
+PCBP2,LPP,0.38604320448181073,destabilizing
+PCBP2,STAG1,0.20936727951037062,destabilizing
+PCBP2,CAPZA2,0.27678175797600496,destabilizing
+PCBP2,ADGRL3,0.1637389028835719,destabilizing
+PCBP2,PHACTR1,0.15579449201683884,destabilizing
+PCBP2,UBE2R2,0.26988904078784454,destabilizing
+PCBP2,GTF2IRD1,0.2325905340843148,destabilizing
+PCBP2,CCBE1,0.17150899790280755,destabilizing
+PCBP2,FTX,0.09061167804881647,destabilizing
+PCBP2,VAPA,0.09701720844787419,destabilizing
+PCBP2,JMJD1C,0.09142460294514765,destabilizing
+PCBP2,TTC28,0.19092001604686043,destabilizing
+PCBP2,SBNO1,0.17508414107813136,destabilizing
+PCBP2,RIMS2,0.18213603523471214,destabilizing
+PCBP2,IGF1R,0.12375437295411774,destabilizing
+PCBP2,TRIO,0.14154370654317774,destabilizing
+PCBP2,KCND2,0.0883717475334227,destabilizing
+PCBP2,BTBD9,0.2829702617146906,destabilizing
+PCBP2,CNGB1,0.31833704734575186,destabilizing
+PCBP2,FMN2,0.2465618872159926,destabilizing
+PCBP2,ENSG00000228222,0.4286468612917422,destabilizing
+PCBP2,ATXN1,0.1314670608016333,destabilizing
+PCBP2,SYN3,0.08251469832669127,destabilizing
+PCBP2,PRKN,0.3778434658816594,destabilizing
+PCBP2,RASA2,0.2810129841832388,destabilizing
+PCBP2,PPP1R12B,0.24960912516813713,destabilizing
+PCBP2,FRMD4A,0.22813304802742307,destabilizing
+PCBP2,CAMK1D,0.14414787581876679,destabilizing
+PCBP2,PARD3,0.10244080276829617,destabilizing
+PCBP2,SEMA6D,0.2668992043346254,destabilizing
+PCBP2,WIPF2,0.276985333064108,destabilizing
+PCBP2,WWOX,0.06543800496156514,destabilizing
+PCBP2,DLEU1,0.41564690431155327,destabilizing
+PCBP2,TSHZ2,0.14059510112630805,destabilizing
+PCBP2,MED13L,0.1715124272098401,destabilizing
+PCBP2,AFF3,0.08701724330444938,destabilizing
+PCBP2,KAZN,0.2506510892215689,destabilizing
+PCBP2,KANSL1,0.1931579967543803,destabilizing
+PCBP2,FRMD5,0.23293967933088602,destabilizing
+PCBP2,LINC00174,0.26500169084833636,destabilizing
+PCBP2,PPM1E,0.2258541988039736,destabilizing
+PCBP2,ARL3,0.16066314455536965,destabilizing
+PCBP2,MBD5,0.23615061297263232,destabilizing
+PCBP2,ELAVL3,0.23032295533366293,destabilizing
+PCBP2,SLIT2,0.3819928144548193,destabilizing
+PCBP2,SLC8A1,0.12703849373737344,destabilizing
+PCBP2,CLASP1,0.22800105488567818,destabilizing
+PCBP2,DOCK4,0.10321445324137164,destabilizing
+PCBP2,UNC5C,0.28273293006098343,destabilizing
+PCBP2,CACNA2D3,-0.0863047932839298,stabilizing
+PCBP2,RC3H1,0.18216477400764133,destabilizing
+PCBP2,NEGR1,0.25230065476179236,destabilizing
+PCBP2,ENOX1,0.3823151978421774,destabilizing
+PCBP2,SCUBE1,0.13778701303355392,destabilizing
+PCBP2,GPHN,0.22549044370520946,destabilizing
+PCBP2,NAV3,0.29561031889878087,destabilizing
+PCBP2,EBF1,0.13269105642360576,destabilizing
+PCBP2,TOMM22,0.31526785545173763,destabilizing
+PCBP2,MBNL2,0.14260964325626474,destabilizing
+PCBP2,ANKFN1,0.11577067676229175,destabilizing
+PCBP2,MAGI2,0.13899846337688437,destabilizing
+PCBP2,LSAMP,0.1616415170670331,destabilizing
+PCBP2,AKAP6,0.28768284497193186,destabilizing
+PCBP2,TMED2,0.20950964660101928,destabilizing
+PCBP2,ZBTB20,0.30482169153102556,destabilizing
+PCBP2,GRIK2,0.22912278644846093,destabilizing
+PCBP2,MAML3,0.056418944562171926,destabilizing
+PCBP2,SOX5,0.21688451261484487,destabilizing
+PCBP2,LRRC37A3,0.33706483319037206,destabilizing
+PCBP2,TMEM132C,0.08549761503940131,destabilizing
+PCBP2,EYS,0.21245666618484274,destabilizing
+PCBP2,ARID1B,0.203125243002592,destabilizing
+PCBP2,PRKCE,0.1803539921646839,destabilizing
+PCBP2,RBFOX1,-0.08757868613696428,stabilizing
+PCBP2,SDK1,0.15398028747810844,destabilizing
+PCBP2,NRG1,0.1415140699433013,destabilizing
+PCBP2,RORA,0.05136710096327728,destabilizing
+PCBP2,MLLT3,0.3710989544290582,destabilizing
+PCBP2,AUTS2,0.06685464842317318,destabilizing
+PCBP2,FMN1,0.1512130204104057,destabilizing
+PCBP2,ADGRB3,0.16295693010750756,destabilizing
+PCBP2,ROBO1,0.2742272404035787,destabilizing
+PCBP2,SYPL1,0.172595256814316,destabilizing
+PCBP2,PTPRD,0.23603602807548843,destabilizing
+PCBP2,FAM155A,0.3371323726476168,destabilizing
+PCBP2,LARP1B,0.3295037584400265,destabilizing
+PCBP3,TRERF1,0.14802725512378984,destabilizing
+PCBP3,SORCS1,0.11273705104697425,destabilizing
+PCBP3,NCOA1,0.05823846447990958,destabilizing
+PCBP3,COPA,0.07910644711918988,destabilizing
+PCBP3,PDE3A,0.15034806156889838,destabilizing
+PCBP3,UNC79,0.1671605842375599,destabilizing
+PCBP3,DOC2B,0.1264803226423353,destabilizing
+PCBP3,TMTC2,0.15935099544379927,destabilizing
+PCBP3,KALRN,0.10702109576024951,destabilizing
+PCBP3,CHD1,0.08463426170365394,destabilizing
+PCBP3,PAK3,0.05386047745992369,destabilizing
+PCBP3,UBE2E2,0.08368271232943761,destabilizing
+PCBP3,PPARD,0.08021483654348596,destabilizing
+PCBP3,BRAF,0.06469923202155177,destabilizing
+PCBP3,RYR2,0.12960364964020518,destabilizing
+PCBP3,MTMR7,0.170740055146864,destabilizing
+PCBP3,EIF4E,0.1182795714994319,destabilizing
+PCBP3,SOX11,0.053699170852133105,destabilizing
+PCBP3,EPB41L4B,0.08769528812870656,destabilizing
+PCBP3,CACNA1B,0.09489122305814633,destabilizing
+PCBP3,LRRTM4,0.09646138311872737,destabilizing
+PCBP3,SIRPA,0.12464655813426168,destabilizing
+PCBP3,PTEN,0.10523200137096207,destabilizing
+PCBP3,FRY,0.1702382742213565,destabilizing
+PCBP3,MACROD2,0.124659281074188,destabilizing
+PCBP3,SHANK2,0.1923055937162985,destabilizing
+PCBP3,CDK12,0.20081755150094865,destabilizing
+PCBP3,RFX7,0.12083133554245293,destabilizing
+PCBP3,UBR5,0.07959294075186234,destabilizing
+PCBP3,JARID2,0.08695647839500352,destabilizing
+PCBP3,MPHOSPH8,0.12738482433472859,destabilizing
+PCBP3,DIP2C,0.10058009120094397,destabilizing
+PCBP3,ZNF423,0.06039228850802143,destabilizing
+PCBP3,UBR3,0.10371881024613586,destabilizing
+PCBP3,MGAT5,0.07498536354166176,destabilizing
+PCBP3,DLG2,0.09868875281577556,destabilizing
+PCBP3,CHST12,0.24719295592738136,destabilizing
+PCBP3,EML5,0.16418050373992002,destabilizing
+PCBP3,CENPP,0.13872801040974675,destabilizing
+PCBP3,PSME4,0.11923497326089888,destabilizing
+PCBP3,TMEM106B,0.16219469819355326,destabilizing
+PCBP3,EPHA5,0.10402058252762678,destabilizing
+PCBP3,KCNB2,0.12054719115990947,destabilizing
+PCBP3,ZNF83,0.0774920378969208,destabilizing
+PCBP3,SOX6,0.0817855314210459,destabilizing
+PCBP3,ZNF521,0.13318285876887465,destabilizing
+PCBP3,PLEKHA5,0.08205940881259044,destabilizing
+PCBP3,NOVA1,0.15934026944485857,destabilizing
+PCBP3,CCNY,0.12488504235844357,destabilizing
+PCBP3,ARIH1,0.11081274853198281,destabilizing
+PCBP3,FAM171B,0.06510255448241054,destabilizing
+PCBP3,EPB41L5,0.10626650107823746,destabilizing
+PCBP3,GPR158,0.1558581450487917,destabilizing
+PCBP3,NCOA2,0.11639838775796307,destabilizing
+PCBP3,ALK,0.1159240971237741,destabilizing
+PCBP3,ACACA,0.07883460772177266,destabilizing
+PCBP3,ARHGAP26,0.06080365381828058,destabilizing
+PCBP3,CTNND2,0.06256336951861088,destabilizing
+PCBP3,IFT172,0.11871365423363518,destabilizing
+PCBP3,CCNT1,0.11371449439884511,destabilizing
+PCBP3,DTWD2,0.14363328044582402,destabilizing
+PCBP3,SIK3,0.14136088147361642,destabilizing
+PCBP3,CPEB3,0.13982563992472685,destabilizing
+PCBP3,CADM2,0.06778254557890706,destabilizing
+PCBP3,XKR6,0.1543143926250008,destabilizing
+PCBP3,CADPS,0.08161720010432542,destabilizing
+PCBP3,FGF13,0.07742457505868107,destabilizing
+PCBP3,TCF20,0.1559023063219578,destabilizing
+PCBP3,DGKI,0.10883708369480387,destabilizing
+PCBP3,EXOC6B,0.17121201402324224,destabilizing
+PCBP3,MAGI3,0.14050555982337523,destabilizing
+PCBP3,SBF2,0.08935666150969622,destabilizing
+PCBP3,INPP4B,0.13261251225236947,destabilizing
+PCBP3,ERC1,0.06617074053472487,destabilizing
+PCBP3,PTPRS,0.16020635138767791,destabilizing
+PCBP3,CBFA2T2,0.08383543527099609,destabilizing
+PCBP3,SPDYE3,0.11528469011332092,destabilizing
+PCBP3,TMEM178B,0.06703918375688993,destabilizing
+PCBP3,KMT2C,0.054656272293722816,destabilizing
+PCBP3,DMD,0.192454295713706,destabilizing
+PCBP3,EIF4G3,0.0794589218899622,destabilizing
+PCBP3,MCU,0.11697030994520582,destabilizing
+PCBP3,SSH2,0.11679612496918888,destabilizing
+PCBP3,DOCK3,0.1539004688480983,destabilizing
+PCBP3,HS6ST3,0.10892956735845669,destabilizing
+PCBP3,LPP,0.19072070268393956,destabilizing
+PCBP3,STAG1,0.11751870384310056,destabilizing
+PCBP3,CAPZA2,0.1352310317726582,destabilizing
+PCBP3,ADGRL3,0.08022591490879305,destabilizing
+PCBP3,PHACTR1,0.06324004723427856,destabilizing
+PCBP3,UBE2R2,0.14294171279498732,destabilizing
+PCBP3,GTF2IRD1,0.10503862619079579,destabilizing
+PCBP3,CCBE1,0.07965465727512383,destabilizing
+PCBP3,TTC28,0.0870075627790039,destabilizing
+PCBP3,SBNO1,0.07798953061485868,destabilizing
+PCBP3,RIMS2,0.10031386476525003,destabilizing
+PCBP3,IGF1R,0.08575160893462697,destabilizing
+PCBP3,TRIO,0.062493520595667165,destabilizing
+PCBP3,BTBD9,0.16046316420102563,destabilizing
+PCBP3,CNGB1,0.1557015815360836,destabilizing
+PCBP3,FMN2,0.13487080955336608,destabilizing
+PCBP3,ENSG00000228222,0.20241628681148935,destabilizing
+PCBP3,SYN3,0.055783956033032045,destabilizing
+PCBP3,PRKN,0.16199276574614968,destabilizing
+PCBP3,RASA2,0.1542052458415194,destabilizing
+PCBP3,PPP1R12B,0.09843660541889324,destabilizing
+PCBP3,FRMD4A,0.13510428905080554,destabilizing
+PCBP3,CAMK1D,0.0634739296116696,destabilizing
+PCBP3,PARD3,0.05221477999877454,destabilizing
+PCBP3,SEMA6D,0.12143766860812841,destabilizing
+PCBP3,WIPF2,0.13438732632700365,destabilizing
+PCBP3,DLEU1,0.1652600485020885,destabilizing
+PCBP3,TSHZ2,0.09329610502917896,destabilizing
+PCBP3,MED13L,0.09297541441675711,destabilizing
+PCBP3,KAZN,0.12088087792637328,destabilizing
+PCBP3,KANSL1,0.07281264122102507,destabilizing
+PCBP3,FRMD5,0.13731364459306958,destabilizing
+PCBP3,LINC00174,0.1290724257760992,destabilizing
+PCBP3,PPM1E,0.12222546247882812,destabilizing
+PCBP3,ARL3,0.10248221430244539,destabilizing
+PCBP3,MBD5,0.10112442198352707,destabilizing
+PCBP3,ELAVL3,0.11055331487533773,destabilizing
+PCBP3,SLIT2,0.15088459036505916,destabilizing
+PCBP3,CLASP1,0.1160872400885421,destabilizing
+PCBP3,UNC5C,0.13304851428470688,destabilizing
+PCBP3,CACNA2D3,-0.06239065180524022,stabilizing
+PCBP3,RC3H1,0.11871771767527266,destabilizing
+PCBP3,NEGR1,0.12535838721250372,destabilizing
+PCBP3,ENOX1,0.19832072198238376,destabilizing
+PCBP3,SCUBE1,0.08627293555264678,destabilizing
+PCBP3,GPHN,0.11129951785601304,destabilizing
+PCBP3,NAV3,0.13302046288640382,destabilizing
+PCBP3,EBF1,0.06012702248687896,destabilizing
+PCBP3,TOMM22,0.16973007943729282,destabilizing
+PCBP3,MBNL2,0.08486819406878726,destabilizing
+PCBP3,MAGI2,0.06216505666359853,destabilizing
+PCBP3,LSAMP,0.10368064128072535,destabilizing
+PCBP3,AKAP6,0.1394939488819983,destabilizing
+PCBP3,TMED2,0.11899340532977687,destabilizing
+PCBP3,ZBTB20,0.11851184019200643,destabilizing
+PCBP3,GRIK2,0.1382595403563681,destabilizing
+PCBP3,SOX5,0.08554630362100941,destabilizing
+PCBP3,LRRC37A3,0.17882705136080243,destabilizing
+PCBP3,EYS,0.10019126439859243,destabilizing
+PCBP3,ARID1B,0.0984021163006891,destabilizing
+PCBP3,PRKCE,0.08721903849605513,destabilizing
+PCBP3,RBFOX1,-0.05566129819033196,stabilizing
+PCBP3,NRG1,0.08282312545597686,destabilizing
+PCBP3,MLLT3,0.17158185590437433,destabilizing
+PCBP3,FMN1,0.09276099985548783,destabilizing
+PCBP3,ADGRB3,0.08803053120506549,destabilizing
+PCBP3,ROBO1,0.12212007155949837,destabilizing
+PCBP3,SYPL1,0.08081830396293069,destabilizing
+PCBP3,PTPRD,0.10622638591947199,destabilizing
+PCBP3,FAM155A,0.1331626129574745,destabilizing
+PCBP3,LARP1B,0.14146806043405152,destabilizing
+IGF2BP3,NOVA1,0.0955774459620947,destabilizing
+IGF2BP3,DMD,0.0917046607153112,destabilizing
+IGF2BP3,ENSG00000228222,0.12372020295466002,destabilizing
+IGF2BP3,PTPRD,0.06827720924810778,destabilizing
+FMR1,CENPP,0.11823876725355183,destabilizing
+FXR1,TRERF1,0.15072708043767505,destabilizing
+FXR1,SORCS1,0.10369807977992804,destabilizing
+FXR1,PDE3A,0.18224086965852695,destabilizing
+FXR1,UNC79,0.17005180126369132,destabilizing
+FXR1,DOC2B,0.12260862924511567,destabilizing
+FXR1,TMTC2,0.12935668698951744,destabilizing
+FXR1,KALRN,0.11154635318726933,destabilizing
+FXR1,CHD1,0.09425402575450753,destabilizing
+FXR1,TOX,0.07505475907759693,destabilizing
+FXR1,RYR2,0.13632983077284636,destabilizing
+FXR1,MTMR7,0.1663750829922606,destabilizing
+FXR1,EIF4E,0.1324709226729999,destabilizing
+FXR1,SOX11,0.054710758953532314,destabilizing
+FXR1,EPB41L4B,0.09164271316235031,destabilizing
+FXR1,CACNA1B,0.08760986860833286,destabilizing
+FXR1,LRRTM4,0.11700868080506205,destabilizing
+FXR1,SIRPA,0.11682498254071219,destabilizing
+FXR1,PTEN,0.12185265004768354,destabilizing
+FXR1,FRY,0.15805707785979425,destabilizing
+FXR1,MACROD2,0.16015329689571547,destabilizing
+FXR1,SHANK2,0.19185285152591333,destabilizing
+FXR1,CDK12,0.21781713039264916,destabilizing
+FXR1,RFX7,0.18962338655765631,destabilizing
+FXR1,UBR5,0.06265753159950907,destabilizing
+FXR1,JARID2,0.07019916718943411,destabilizing
+FXR1,MPHOSPH8,0.10406469844361035,destabilizing
+FXR1,DIP2C,0.11096663875017553,destabilizing
+FXR1,UBR3,0.09039271440284265,destabilizing
+FXR1,MGAT5,0.05976021252651693,destabilizing
+FXR1,DLG2,0.10834087890381693,destabilizing
+FXR1,CHST12,0.2221358943978261,destabilizing
+FXR1,EML5,0.14057731964844739,destabilizing
+FXR1,CENPP,0.14290007140920505,destabilizing
+FXR1,PSME4,0.12220470547913342,destabilizing
+FXR1,TMEM106B,0.1395325689912804,destabilizing
+FXR1,EPHA5,0.11962580948156312,destabilizing
+FXR1,KCNB2,0.15141287564081116,destabilizing
+FXR1,ZNF83,0.09981935288109291,destabilizing
+FXR1,SOX6,0.07726268065877455,destabilizing
+FXR1,ZNF521,0.13079275812691601,destabilizing
+FXR1,PLEKHA5,0.08900239792156252,destabilizing
+FXR1,NOVA1,0.18359351221562584,destabilizing
+FXR1,CCNY,0.14925708748717126,destabilizing
+FXR1,ARIH1,0.09679450617085722,destabilizing
+FXR1,EPB41L5,0.10133874556053528,destabilizing
+FXR1,GPR158,0.156291241600866,destabilizing
+FXR1,NCOA2,0.10237505148924927,destabilizing
+FXR1,ALK,0.14224704667502228,destabilizing
+FXR1,ACACA,0.0637400364769458,destabilizing
+FXR1,IFT172,0.1685728101960105,destabilizing
+FXR1,CCNT1,0.06806017015037238,destabilizing
+FXR1,DTWD2,0.1478400895520146,destabilizing
+FXR1,SIK3,0.10830525310602433,destabilizing
+FXR1,CPEB3,0.15627500524679983,destabilizing
+FXR1,CADM2,0.06229572910667075,destabilizing
+FXR1,XKR6,0.1738285953743153,destabilizing
+FXR1,CADPS,0.10083818905447758,destabilizing
+FXR1,TCF20,0.13032819887182018,destabilizing
+FXR1,DGKI,0.10449588521930248,destabilizing
+FXR1,EXOC6B,0.15899344450459668,destabilizing
+FXR1,MAGI3,0.14523773793714367,destabilizing
+FXR1,SBF2,0.07362832451659722,destabilizing
+FXR1,INPP4B,0.12040731885307293,destabilizing
+FXR1,PTPRS,0.21085681004347917,destabilizing
+FXR1,CBFA2T2,0.061093981242636916,destabilizing
+FXR1,SPDYE3,0.10602848222817995,destabilizing
+FXR1,TMEM178B,0.06822789372346354,destabilizing
+FXR1,DMD,0.21850800223352734,destabilizing
+FXR1,MCU,0.1275727948751203,destabilizing
+FXR1,SSH2,0.10475400922503972,destabilizing
+FXR1,DOCK3,0.15531894917073585,destabilizing
+FXR1,HS6ST3,0.14880321743827296,destabilizing
+FXR1,LPP,0.1635506154854482,destabilizing
+FXR1,STAG1,0.08163431392651284,destabilizing
+FXR1,CAPZA2,0.1284131073554688,destabilizing
+FXR1,ADGRL3,0.0834001008513854,destabilizing
+FXR1,UBE2R2,0.1250809679459418,destabilizing
+FXR1,GTF2IRD1,0.11580896262388926,destabilizing
+FXR1,CCBE1,0.060568101021226124,destabilizing
+FXR1,TTC28,0.08724661890280405,destabilizing
+FXR1,SBNO1,0.0754632415826063,destabilizing
+FXR1,RIMS2,0.07443373988919685,destabilizing
+FXR1,TRIO,0.061923138201392613,destabilizing
+FXR1,KCND2,0.05847285772383956,destabilizing
+FXR1,BTBD9,0.11455781738909535,destabilizing
+FXR1,CNGB1,0.1728562728387773,destabilizing
+FXR1,FMN2,0.0933390731994595,destabilizing
+FXR1,ENSG00000228222,0.206882590130842,destabilizing
+FXR1,PRKN,0.15586376504918295,destabilizing
+FXR1,RASA2,0.13704362025572148,destabilizing
+FXR1,PPP1R12B,0.09557548933296843,destabilizing
+FXR1,FRMD4A,0.09065555656420307,destabilizing
+FXR1,SEMA6D,0.1138815790553056,destabilizing
+FXR1,WIPF2,0.12805357238008053,destabilizing
+FXR1,DLEU1,0.16672296669582493,destabilizing
+FXR1,TSHZ2,0.07904942132037929,destabilizing
+FXR1,MED13L,0.07647486487835442,destabilizing
+FXR1,KAZN,0.12976994267917952,destabilizing
+FXR1,KANSL1,0.07503157669270853,destabilizing
+FXR1,FRMD5,0.13844089660772035,destabilizing
+FXR1,LINC00174,0.12506308630275598,destabilizing
+FXR1,PPM1E,0.11544910092113742,destabilizing
+FXR1,ARL3,0.08676919395671072,destabilizing
+FXR1,MBD5,0.12288602056318547,destabilizing
+FXR1,ELAVL3,0.13324392793219433,destabilizing
+FXR1,SLIT2,0.19205763555186434,destabilizing
+FXR1,CLASP1,0.08929444143430694,destabilizing
+FXR1,UNC5C,0.13817519415216423,destabilizing
+FXR1,RC3H1,0.0697930693578269,destabilizing
+FXR1,NEGR1,0.15785650641413487,destabilizing
+FXR1,ENOX1,0.1679593663613213,destabilizing
+FXR1,SCUBE1,0.06487273352920367,destabilizing
+FXR1,GPHN,0.10923446572425509,destabilizing
+FXR1,NAV3,0.17682854231997866,destabilizing
+FXR1,EBF1,0.05762792152404155,destabilizing
+FXR1,TOMM22,0.15965260057350425,destabilizing
+FXR1,MAGI2,0.05857174119015547,destabilizing
+FXR1,LSAMP,0.07016846502816618,destabilizing
+FXR1,AKAP6,0.11163654841048624,destabilizing
+FXR1,TMED2,0.095572349382798,destabilizing
+FXR1,ZBTB20,0.14947694972262152,destabilizing
+FXR1,GRIK2,0.1198356313753184,destabilizing
+FXR1,SOX5,0.09238824084620312,destabilizing
+FXR1,LRRC37A3,0.15476811127194431,destabilizing
+FXR1,EYS,0.09137284624465336,destabilizing
+FXR1,ARID1B,0.09510280191939896,destabilizing
+FXR1,PRKCE,0.0833789581928687,destabilizing
+FXR1,RBFOX1,-0.06947166093153664,stabilizing
+FXR1,SDK1,0.06838335203830366,destabilizing
+FXR1,NRG1,0.06280638346855957,destabilizing
+FXR1,MLLT3,0.2115717641056164,destabilizing
+FXR1,ADGRB3,0.06646688151941764,destabilizing
+FXR1,ROBO1,0.1390772437189607,destabilizing
+FXR1,SYPL1,0.062147371017722504,destabilizing
+FXR1,PTPRD,0.11911197985929232,destabilizing
+FXR1,FAM155A,0.16259403730047106,destabilizing
+FXR1,LARP1B,0.14111710102248068,destabilizing
+FXR2,UNC79,0.10383766123958507,destabilizing
+FXR2,DOC2B,0.07463788336989981,destabilizing
+FXR2,KALRN,0.06364742529987315,destabilizing
+FXR2,MTMR7,0.08564255358175467,destabilizing
+FXR2,EIF4E,0.10430773092309391,destabilizing
+FXR2,FRY,0.09184839451828714,destabilizing
+FXR2,MACROD2,0.07604484503104578,destabilizing
+FXR2,SHANK2,0.11510703859923745,destabilizing
+FXR2,CDK12,0.12612522136618542,destabilizing
+FXR2,MPHOSPH8,0.06777295773153033,destabilizing
+FXR2,DLG2,0.08175479094235776,destabilizing
+FXR2,CHST12,0.14782297586135845,destabilizing
+FXR2,EML5,0.07795898171173365,destabilizing
+FXR2,CENPP,0.12213641252518308,destabilizing
+FXR2,TMEM106B,0.10378363330370137,destabilizing
+FXR2,KCNB2,0.11580690897166865,destabilizing
+FXR2,SOX6,0.060712498580887356,destabilizing
+FXR2,NOVA1,0.11852391736690508,destabilizing
+FXR2,CCNY,0.1059927802264663,destabilizing
+FXR2,ARIH1,0.06463431610490583,destabilizing
+FXR2,GPR158,0.11162484801803245,destabilizing
+FXR2,NCOA2,0.075830867408619,destabilizing
+FXR2,IFT172,0.08547253202183466,destabilizing
+FXR2,DTWD2,0.14723411282503676,destabilizing
+FXR2,CPEB3,0.11551436938964993,destabilizing
+FXR2,XKR6,0.12288105906220041,destabilizing
+FXR2,CADPS,0.05617195627342133,destabilizing
+FXR2,DGKI,0.07645153959568263,destabilizing
+FXR2,MAGI3,0.08281128303561981,destabilizing
+FXR2,INPP4B,0.0861744522570078,destabilizing
+FXR2,DMD,0.13499157665070172,destabilizing
+FXR2,DOCK3,0.11051221670579817,destabilizing
+FXR2,CAPZA2,0.07329078600759328,destabilizing
+FXR2,CNGB1,0.08170632032362345,destabilizing
+FXR2,ENSG00000228222,0.1201992441544733,destabilizing
+FXR2,PRKN,0.10888994298665142,destabilizing
+FXR2,RASA2,0.08336824563815946,destabilizing
+FXR2,PPP1R12B,0.06666628082031797,destabilizing
+FXR2,FRMD4A,0.06315580226116155,destabilizing
+FXR2,SEMA6D,0.07901118758194729,destabilizing
+FXR2,WIPF2,0.08962713885323564,destabilizing
+FXR2,LINC00174,0.06326395567538319,destabilizing
+FXR2,MBD5,0.0730499613911698,destabilizing
+FXR2,ELAVL3,0.06379361965373734,destabilizing
+FXR2,SLIT2,0.09754246552002176,destabilizing
+FXR2,UNC5C,0.09262668435149904,destabilizing
+FXR2,NEGR1,0.0952897846626861,destabilizing
+FXR2,ENOX1,0.14993695579915242,destabilizing
+FXR2,NAV3,0.07823433436328084,destabilizing
+FXR2,TOMM22,0.10664926157119857,destabilizing
+FXR2,AKAP6,0.07399356391651767,destabilizing
+FXR2,ZBTB20,0.07257325237212177,destabilizing
+FXR2,LRRC37A3,0.09572566779706392,destabilizing
+FXR2,EYS,0.05664563250169388,destabilizing
+FXR2,MLLT3,0.11164224068592893,destabilizing
+FXR2,LARP1B,0.062280127625899954,destabilizing
+MBNL2,UNC79,0.09388125485470455,destabilizing
+MBNL2,TMTC2,0.07656081119428336,destabilizing
+MBNL2,MACROD2,0.07239506629479234,destabilizing
+MBNL2,CDK12,0.1122404385222683,destabilizing
+MBNL2,EML5,0.08167451979208379,destabilizing
+MBNL2,TMEM106B,0.09596629071000126,destabilizing
+MBNL2,XKR6,0.07711724907788786,destabilizing
+MBNL2,EXOC6B,0.08804874466095697,destabilizing
+MBNL2,PTPRS,0.13967279858806161,destabilizing
+MBNL2,LPP,0.1107908347867332,destabilizing
+MBNL2,ELAVL3,0.061435052314376154,destabilizing
+MBNL2,MBNL2,-0.33793877167390185,stabilizing
+MBNL2,LARP1B,0.06947679617138144,destabilizing
+CELF1,DMD,0.07987156865061115,destabilizing
+CELF1,MLLT3,0.08784879195952248,destabilizing
+CELF2,TRERF1,0.07896698932455697,destabilizing
+CELF2,FRY,0.09008367782166721,destabilizing
+CELF2,CDK12,0.09709541675415485,destabilizing
+CELF2,MPHOSPH8,0.06626655932285312,destabilizing
+CELF2,CENPP,0.12130499666493208,destabilizing
+CELF2,NOVA1,0.0929192958542478,destabilizing
+CELF2,CCNT1,0.05733028939293565,destabilizing
+CELF2,MAGI3,0.06740726622852057,destabilizing
+CELF2,DMD,0.09082721404403789,destabilizing
+CELF2,DOCK3,0.10285946782032246,destabilizing
+CELF2,PTPRD,0.0635592341357154,destabilizing
+CELF4,TRERF1,0.12236148380498647,destabilizing
+CELF4,SORCS1,0.07722109314321123,destabilizing
+CELF4,PDE3A,0.12728379414884913,destabilizing
+CELF4,UNC79,0.12862863058740195,destabilizing
+CELF4,DOC2B,0.08629133537736836,destabilizing
+CELF4,TMTC2,0.11485434360392974,destabilizing
+CELF4,KALRN,0.10625579385293304,destabilizing
+CELF4,CHD1,0.055908552973819435,destabilizing
+CELF4,MTMR7,0.14240419401091053,destabilizing
+CELF4,EPB41L4B,0.10474261780141628,destabilizing
+CELF4,CACNA1B,0.07954454176422268,destabilizing
+CELF4,LRRTM4,0.08908620966834366,destabilizing
+CELF4,FRY,0.10493630534891522,destabilizing
+CELF4,MACROD2,0.11122604925059618,destabilizing
+CELF4,SHANK2,0.13613785872950565,destabilizing
+CELF4,CDK12,0.1462420236743995,destabilizing
+CELF4,RFX7,0.12910910694287414,destabilizing
+CELF4,JARID2,0.05696171992297806,destabilizing
+CELF4,MPHOSPH8,0.08714739337805906,destabilizing
+CELF4,DIP2C,0.0729629238406677,destabilizing
+CELF4,UBR3,0.07809002168771989,destabilizing
+CELF4,MGAT5,0.05268236700735613,destabilizing
+CELF4,DLG2,0.06174336665115663,destabilizing
+CELF4,CHST12,0.20032644000040864,destabilizing
+CELF4,EML5,0.13390093688013296,destabilizing
+CELF4,PSME4,0.10542072822529816,destabilizing
+CELF4,TMEM106B,0.09644695290389968,destabilizing
+CELF4,EPHA5,0.09819922137407126,destabilizing
+CELF4,KCNB2,0.09109430688677507,destabilizing
+CELF4,ZNF83,0.08386348111003318,destabilizing
+CELF4,SOX6,0.07934531149196847,destabilizing
+CELF4,ZNF521,0.12516529046026736,destabilizing
+CELF4,PLEKHA5,0.05713566825979742,destabilizing
+CELF4,NOVA1,0.1220373147414334,destabilizing
+CELF4,CCNY,0.09664228361723654,destabilizing
+CELF4,ARIH1,0.0791187402258273,destabilizing
+CELF4,EPB41L5,0.08658907361318208,destabilizing
+CELF4,GPR158,0.11690721239155928,destabilizing
+CELF4,NCOA2,0.07972295558729903,destabilizing
+CELF4,ACACA,0.05574011917795647,destabilizing
+CELF4,IFT172,0.10628537527787094,destabilizing
+CELF4,CCNT1,0.054936559113727204,destabilizing
+CELF4,CPEB3,0.10832877097683469,destabilizing
+CELF4,CADM2,0.07358393435666509,destabilizing
+CELF4,XKR6,0.11254707026679243,destabilizing
+CELF4,CADPS,0.06055365009720584,destabilizing
+CELF4,TCF20,0.10544394653489703,destabilizing
+CELF4,CDKAL1,0.09274161950339622,destabilizing
+CELF4,DGKI,0.08327365792539711,destabilizing
+CELF4,EXOC6B,0.11470104973837698,destabilizing
+CELF4,MAGI3,0.09557618181001806,destabilizing
+CELF4,INPP4B,0.12447068372902685,destabilizing
+CELF4,PTPRS,0.11938066157034871,destabilizing
+CELF4,SPDYE3,0.0700879014574669,destabilizing
+CELF4,DMD,0.14205154861167532,destabilizing
+CELF4,MCU,0.06630688751976956,destabilizing
+CELF4,SSH2,0.08194534867565627,destabilizing
+CELF4,DOCK3,0.10988708033304943,destabilizing
+CELF4,HS6ST3,0.14226187066033333,destabilizing
+CELF4,LPP,0.13628565505541665,destabilizing
+CELF4,STAG1,0.10731826226422261,destabilizing
+CELF4,CAPZA2,0.1195153377455562,destabilizing
+CELF4,ADGRL3,0.08463772831617784,destabilizing
+CELF4,UBE2R2,0.1116290760106137,destabilizing
+CELF4,GTF2IRD1,0.08619345195527381,destabilizing
+CELF4,CCBE1,0.05764714962708973,destabilizing
+CELF4,TTC28,0.09251703130580399,destabilizing
+CELF4,RIMS2,0.06604096545330877,destabilizing
+CELF4,IGF1R,0.059863038079943275,destabilizing
+CELF4,BTBD9,0.09557280539500038,destabilizing
+CELF4,CNGB1,0.16046052986359785,destabilizing
+CELF4,FMN2,0.08946315700323688,destabilizing
+CELF4,ENSG00000228222,0.18785503066169576,destabilizing
+CELF4,ATXN1,0.058152372042689096,destabilizing
+CELF4,PRKN,0.16757048658088847,destabilizing
+CELF4,RASA2,0.0988482989618312,destabilizing
+CELF4,PPP1R12B,0.06491605706511756,destabilizing
+CELF4,FRMD4A,0.0922287260925091,destabilizing
+CELF4,SEMA6D,0.09195483175199469,destabilizing
+CELF4,WIPF2,0.11436512833410845,destabilizing
+CELF4,DLEU1,0.10792842681703364,destabilizing
+CELF4,KAZN,0.0912165900989643,destabilizing
+CELF4,FRMD5,0.08825016345918123,destabilizing
+CELF4,LINC00174,0.0957690613885284,destabilizing
+CELF4,ARL3,0.06265708119941182,destabilizing
+CELF4,MBD5,0.0692245313996718,destabilizing
+CELF4,ELAVL3,0.09596159751947114,destabilizing
+CELF4,SLIT2,0.15141881189684578,destabilizing
+CELF4,CLASP1,0.07386114586050992,destabilizing
+CELF4,UNC5C,0.10946062256202377,destabilizing
+CELF4,CACNA2D3,-0.05623668498053921,stabilizing
+CELF4,RC3H1,0.06336831005531234,destabilizing
+CELF4,NEGR1,0.11730764199761139,destabilizing
+CELF4,ENOX1,0.14366438875340506,destabilizing
+CELF4,SCUBE1,0.07614579978392079,destabilizing
+CELF4,GPHN,0.0916979775780614,destabilizing
+CELF4,NAV3,0.11329636960826962,destabilizing
+CELF4,TOMM22,0.14284156297932873,destabilizing
+CELF4,LSAMP,0.05847915431759243,destabilizing
+CELF4,AKAP6,0.11466275151769792,destabilizing
+CELF4,TMED2,0.07779793330834461,destabilizing
+CELF4,ZBTB20,0.07819809349325939,destabilizing
+CELF4,GRIK2,0.1073201637168304,destabilizing
+CELF4,LRRC37A3,0.14797008449629917,destabilizing
+CELF4,EYS,0.08454401950568899,destabilizing
+CELF4,ARID1B,0.07313682338606782,destabilizing
+CELF4,RBFOX1,-0.06647754857604969,stabilizing
+CELF4,SDK1,0.07187613876237743,destabilizing
+CELF4,MLLT3,0.16663863702665016,destabilizing
+CELF4,ADGRB3,0.07336035797796,destabilizing
+CELF4,ROBO1,0.10213539529187407,destabilizing
+CELF4,SYPL1,0.05939916488960753,destabilizing
+CELF4,PTPRD,0.10041301417599187,destabilizing
+CELF4,FAM155A,0.11579864736504782,destabilizing
+CELF4,LARP1B,0.10848351062685692,destabilizing
+QKI,PUM2,-0.05703765625713527,stabilizing
+KHDRBS1,TRERF1,0.17397449909392249,destabilizing
+KHDRBS1,SORCS1,0.10027424965326717,destabilizing
+KHDRBS1,NCOA1,0.05919444911649349,destabilizing
+KHDRBS1,COPA,0.07376519760033752,destabilizing
+KHDRBS1,FCHSD2,0.08830993899630304,destabilizing
+KHDRBS1,PDE3A,0.18505531631781083,destabilizing
+KHDRBS1,UNC79,0.17987778319426886,destabilizing
+KHDRBS1,DOC2B,0.14535523935767397,destabilizing
+KHDRBS1,TMTC2,0.19573303452507007,destabilizing
+KHDRBS1,KALRN,0.13584963947778278,destabilizing
+KHDRBS1,CHD1,0.07241135291585962,destabilizing
+KHDRBS1,PAK3,0.057503556600839126,destabilizing
+KHDRBS1,UBE2E2,0.08043214475213464,destabilizing
+KHDRBS1,PPARD,0.09046945750684217,destabilizing
+KHDRBS1,TOX,0.0868128087544013,destabilizing
+KHDRBS1,BRAF,0.08822925705835381,destabilizing
+KHDRBS1,RYR2,0.19294655895795304,destabilizing
+KHDRBS1,MTMR7,0.19114916039411478,destabilizing
+KHDRBS1,EIF4E,0.19302890143629756,destabilizing
+KHDRBS1,EPB41L4B,0.0973558824152688,destabilizing
+KHDRBS1,CACNA1B,0.10406419950962303,destabilizing
+KHDRBS1,TBC1D5,0.05906031054324232,destabilizing
+KHDRBS1,LRRTM4,0.11939073255638136,destabilizing
+KHDRBS1,SIRPA,0.12888211428063207,destabilizing
+KHDRBS1,PTEN,0.12879750105957485,destabilizing
+KHDRBS1,FRY,0.19830762288245862,destabilizing
+KHDRBS1,RUNX1T1,0.0710035951852661,destabilizing
+KHDRBS1,MACROD2,0.17848257076669682,destabilizing
+KHDRBS1,SHANK2,0.2106962818177205,destabilizing
+KHDRBS1,CDK12,0.2460682654088887,destabilizing
+KHDRBS1,RFX7,0.19759975819560377,destabilizing
+KHDRBS1,UBR5,0.07261201828522364,destabilizing
+KHDRBS1,JARID2,0.07625309926628493,destabilizing
+KHDRBS1,MPHOSPH8,0.16733618534617536,destabilizing
+KHDRBS1,DIP2C,0.11337268185498263,destabilizing
+KHDRBS1,ZNF423,0.06255867080161134,destabilizing
+KHDRBS1,UBR3,0.11125026829402145,destabilizing
+KHDRBS1,MGAT5,0.06321261119198383,destabilizing
+KHDRBS1,DLG2,0.1376270302309887,destabilizing
+KHDRBS1,CHST12,0.25622345172674593,destabilizing
+KHDRBS1,EML5,0.20478693416451446,destabilizing
+KHDRBS1,CENPP,0.23714215632842905,destabilizing
+KHDRBS1,PSME4,0.1532032291297778,destabilizing
+KHDRBS1,TMEM106B,0.1786973252492116,destabilizing
+KHDRBS1,EPHA5,0.13802833615868876,destabilizing
+KHDRBS1,KCNB2,0.19571311588182305,destabilizing
+KHDRBS1,ZNF83,0.10651199203404195,destabilizing
+KHDRBS1,SOX6,0.12473569352272405,destabilizing
+KHDRBS1,ZNF521,0.15543498970608743,destabilizing
+KHDRBS1,PLEKHA5,0.09891243581138723,destabilizing
+KHDRBS1,NOVA1,0.19683560612499876,destabilizing
+KHDRBS1,CCNY,0.15563754404405386,destabilizing
+KHDRBS1,ARIH1,0.1288674677844355,destabilizing
+KHDRBS1,EPB41L5,0.1126259976775492,destabilizing
+KHDRBS1,GPR158,0.18659417469691703,destabilizing
+KHDRBS1,NCOA2,0.11635700034478458,destabilizing
+KHDRBS1,ALK,0.21163477031274033,destabilizing
+KHDRBS1,CTNND2,0.07236627819743277,destabilizing
+KHDRBS1,IFT172,0.17091989904153082,destabilizing
+KHDRBS1,CCNT1,0.10065664386090684,destabilizing
+KHDRBS1,DTWD2,0.3277369841429196,destabilizing
+KHDRBS1,SIK3,0.13601349052299133,destabilizing
+KHDRBS1,CPEB3,0.2072780330506742,destabilizing
+KHDRBS1,CADM2,0.0864036439919764,destabilizing
+KHDRBS1,XKR6,0.18696641613028428,destabilizing
+KHDRBS1,RMND5A,0.06490519996019468,destabilizing
+KHDRBS1,CADPS,0.08711821779801009,destabilizing
+KHDRBS1,FGF13,0.07977810850144096,destabilizing
+KHDRBS1,TCF20,0.15325354751702286,destabilizing
+KHDRBS1,CDKAL1,0.07558764875355435,destabilizing
+KHDRBS1,DGKI,0.14109980659791052,destabilizing
+KHDRBS1,EXOC6B,0.19160630716631447,destabilizing
+KHDRBS1,MAGI3,0.15457250167092892,destabilizing
+KHDRBS1,SBF2,0.07675681819494787,destabilizing
+KHDRBS1,INPP4B,0.11997600786035571,destabilizing
+KHDRBS1,ERC1,0.06269691804558124,destabilizing
+KHDRBS1,PTPRS,0.18733014397943193,destabilizing
+KHDRBS1,CBFA2T2,0.06032168988246189,destabilizing
+KHDRBS1,SPDYE3,0.12538009220882834,destabilizing
+KHDRBS1,TMEM178B,0.08441833356185066,destabilizing
+KHDRBS1,DMD,0.2425945065421184,destabilizing
+KHDRBS1,EIF4G3,0.06681873757682985,destabilizing
+KHDRBS1,MCU,0.16046390552782927,destabilizing
+KHDRBS1,SSH2,0.15254995582805808,destabilizing
+KHDRBS1,DOCK3,0.21431828985047607,destabilizing
+KHDRBS1,HS6ST3,0.19211657611896185,destabilizing
+KHDRBS1,LPP,0.17797221817874634,destabilizing
+KHDRBS1,STAG1,0.11749195809689429,destabilizing
+KHDRBS1,CAPZA2,0.16133206879613537,destabilizing
+KHDRBS1,ADGRL3,0.09003049346784257,destabilizing
+KHDRBS1,PHACTR1,0.0922818494125254,destabilizing
+KHDRBS1,UBE2R2,0.12581463735907744,destabilizing
+KHDRBS1,GTF2IRD1,0.10857067488133329,destabilizing
+KHDRBS1,CCBE1,0.07070918696826839,destabilizing
+KHDRBS1,FTX,0.07307805286284506,destabilizing
+KHDRBS1,VAPA,0.0654524970526244,destabilizing
+KHDRBS1,TTC28,0.10512861477352595,destabilizing
+KHDRBS1,SBNO1,0.08800333468656149,destabilizing
+KHDRBS1,RIMS2,0.11775892927537039,destabilizing
+KHDRBS1,KCND2,0.05836471531418555,destabilizing
+KHDRBS1,BTBD9,0.15182741526645027,destabilizing
+KHDRBS1,CNGB1,0.16070189465376386,destabilizing
+KHDRBS1,FMN2,0.11868199353753298,destabilizing
+KHDRBS1,ENSG00000228222,0.2331806089390625,destabilizing
+KHDRBS1,ATXN1,0.07673786505485161,destabilizing
+KHDRBS1,SYN3,0.05096010990954973,destabilizing
+KHDRBS1,PRKN,0.18265814599155947,destabilizing
+KHDRBS1,RASA2,0.1843627694857719,destabilizing
+KHDRBS1,PPP1R12B,0.11759398321409958,destabilizing
+KHDRBS1,FRMD4A,0.10545502326619642,destabilizing
+KHDRBS1,CAMK1D,0.0756336540543325,destabilizing
+KHDRBS1,PARD3,0.06222344819409367,destabilizing
+KHDRBS1,SEMA6D,0.14968895868765195,destabilizing
+KHDRBS1,WIPF2,0.17631786353268367,destabilizing
+KHDRBS1,DLEU1,0.2605740512324363,destabilizing
+KHDRBS1,TSHZ2,0.08367988195601256,destabilizing
+KHDRBS1,MED13L,0.06719529440712198,destabilizing
+KHDRBS1,KAZN,0.12484279797383367,destabilizing
+KHDRBS1,KANSL1,0.11114403638945422,destabilizing
+KHDRBS1,FRMD5,0.11648881468431,destabilizing
+KHDRBS1,LINC00174,0.16323930264012385,destabilizing
+KHDRBS1,PPM1E,0.1315717767110176,destabilizing
+KHDRBS1,ARL3,0.10081937943344109,destabilizing
+KHDRBS1,MBD5,0.13163167590086988,destabilizing
+KHDRBS1,ELAVL3,0.14909505980617158,destabilizing
+KHDRBS1,SLIT2,0.16632678291903213,destabilizing
+KHDRBS1,SLC8A1,0.0724427476270115,destabilizing
+KHDRBS1,CLASP1,0.146024808003421,destabilizing
+KHDRBS1,UNC5C,0.15883240548659708,destabilizing
+KHDRBS1,RC3H1,0.10105376312452169,destabilizing
+KHDRBS1,NEGR1,0.1532160290765907,destabilizing
+KHDRBS1,ENOX1,0.21970542848768457,destabilizing
+KHDRBS1,SCUBE1,0.08199670661628396,destabilizing
+KHDRBS1,GPHN,0.12905303043233238,destabilizing
+KHDRBS1,NAV3,0.15944398248936212,destabilizing
+KHDRBS1,EBF1,0.07183234777364617,destabilizing
+KHDRBS1,TOMM22,0.1932502815621073,destabilizing
+KHDRBS1,MBNL2,0.061279932388292505,destabilizing
+KHDRBS1,ANKFN1,0.0866149050777163,destabilizing
+KHDRBS1,MAGI2,0.058928113366169634,destabilizing
+KHDRBS1,LSAMP,0.09108342666704458,destabilizing
+KHDRBS1,AKAP6,0.15411807919826634,destabilizing
+KHDRBS1,TMED2,0.13131641614364278,destabilizing
+KHDRBS1,ZBTB20,0.18725390802010847,destabilizing
+KHDRBS1,GRIK2,0.14309589175134124,destabilizing
+KHDRBS1,SOX5,0.10782247141360642,destabilizing
+KHDRBS1,LRRC37A3,0.20471769647103655,destabilizing
+KHDRBS1,TMEM132C,0.05894511183102938,destabilizing
+KHDRBS1,EYS,0.10511256513344756,destabilizing
+KHDRBS1,ARID1B,0.08205068395462652,destabilizing
+KHDRBS1,PRKCE,0.08991527993850752,destabilizing
+KHDRBS1,SDK1,0.061911986509503227,destabilizing
+KHDRBS1,NRG1,0.08802039566917667,destabilizing
+KHDRBS1,MLLT3,0.22377555819197598,destabilizing
+KHDRBS1,FMN1,0.09125758250572981,destabilizing
+KHDRBS1,ADGRB3,0.08227276841191797,destabilizing
+KHDRBS1,ROBO1,0.11884892032083388,destabilizing
+KHDRBS1,SYPL1,0.09691669352679079,destabilizing
+KHDRBS1,PTPRD,0.13527276088694937,destabilizing
+KHDRBS1,FAM155A,0.18073356704791743,destabilizing
+KHDRBS1,LARP1B,0.16588555827944054,destabilizing
+KHDRBS3,TRERF1,0.12917881739110348,destabilizing
+KHDRBS3,SORCS1,0.09145194773417496,destabilizing
+KHDRBS3,COPA,0.07202343363313211,destabilizing
+KHDRBS3,FCHSD2,0.0723463817969544,destabilizing
+KHDRBS3,PDE3A,0.1550441729942679,destabilizing
+KHDRBS3,UNC79,0.15905720492508618,destabilizing
+KHDRBS3,DOC2B,0.09903363061757647,destabilizing
+KHDRBS3,TMTC2,0.15932644235300458,destabilizing
+KHDRBS3,KALRN,0.09682590134828359,destabilizing
+KHDRBS3,CHD1,0.0773954940358827,destabilizing
+KHDRBS3,UBE2E2,0.0709335961573655,destabilizing
+KHDRBS3,PPARD,0.06769943240875773,destabilizing
+KHDRBS3,RYR2,0.13525495715349564,destabilizing
+KHDRBS3,MTMR7,0.1484608586747511,destabilizing
+KHDRBS3,EPB41L4B,0.08756586040581744,destabilizing
+KHDRBS3,CACNA1B,0.09769033591229621,destabilizing
+KHDRBS3,LRRTM4,0.099602215878611,destabilizing
+KHDRBS3,SIRPA,0.12218686025530119,destabilizing
+KHDRBS3,PTEN,0.09227819117774526,destabilizing
+KHDRBS3,FRY,0.14989143626617066,destabilizing
+KHDRBS3,MACROD2,0.11517548912847816,destabilizing
+KHDRBS3,SHANK2,0.18342480717367365,destabilizing
+KHDRBS3,CDK12,0.2003693338152593,destabilizing
+KHDRBS3,RFX7,0.13242786292860867,destabilizing
+KHDRBS3,UBR5,0.06926204619566628,destabilizing
+KHDRBS3,JARID2,0.0760702355405439,destabilizing
+KHDRBS3,MPHOSPH8,0.11616251062779312,destabilizing
+KHDRBS3,DIP2C,0.10169517547182634,destabilizing
+KHDRBS3,UBR3,0.07886267854944891,destabilizing
+KHDRBS3,MGAT5,0.0645512034905535,destabilizing
+KHDRBS3,DLG2,0.10561403896857731,destabilizing
+KHDRBS3,CHST12,0.20171046166531476,destabilizing
+KHDRBS3,EML5,0.16410942193284025,destabilizing
+KHDRBS3,CENPP,0.13082783771655637,destabilizing
+KHDRBS3,PSME4,0.12178396483795002,destabilizing
+KHDRBS3,TMEM106B,0.12048860391824738,destabilizing
+KHDRBS3,EPHA5,0.1046809914029778,destabilizing
+KHDRBS3,KCNB2,0.12542186553114862,destabilizing
+KHDRBS3,SOX6,0.07613244607810543,destabilizing
+KHDRBS3,ZNF521,0.09170105353860003,destabilizing
+KHDRBS3,PLEKHA5,0.07758818222074278,destabilizing
+KHDRBS3,NOVA1,0.17700754063577886,destabilizing
+KHDRBS3,CCNY,0.12557821700542637,destabilizing
+KHDRBS3,ARIH1,0.0817721125585807,destabilizing
+KHDRBS3,EPB41L5,0.11546892199864882,destabilizing
+KHDRBS3,GPR158,0.13401372460497946,destabilizing
+KHDRBS3,NCOA2,0.10011526887241888,destabilizing
+KHDRBS3,ALK,0.14358037326110362,destabilizing
+KHDRBS3,IFT172,0.15304999102190495,destabilizing
+KHDRBS3,CCNT1,0.07272236682350129,destabilizing
+KHDRBS3,DTWD2,0.19635797814609468,destabilizing
+KHDRBS3,SIK3,0.09159564798046803,destabilizing
+KHDRBS3,CPEB3,0.15004535602808716,destabilizing
+KHDRBS3,CADM2,0.06214986626835278,destabilizing
+KHDRBS3,XKR6,0.17066014220203898,destabilizing
+KHDRBS3,RMND5A,0.06603410031950906,destabilizing
+KHDRBS3,CADPS,0.06005178090348672,destabilizing
+KHDRBS3,TCF20,0.12580596172929476,destabilizing
+KHDRBS3,CDKAL1,0.08502851630542671,destabilizing
+KHDRBS3,DGKI,0.11343999290664633,destabilizing
+KHDRBS3,EXOC6B,0.1436188491485399,destabilizing
+KHDRBS3,MAGI3,0.13125052503199244,destabilizing
+KHDRBS3,SBF2,0.06549697852246186,destabilizing
+KHDRBS3,INPP4B,0.11349541803659538,destabilizing
+KHDRBS3,ERC1,0.06263221905385251,destabilizing
+KHDRBS3,PTPRS,0.1692886027960379,destabilizing
+KHDRBS3,CBFA2T2,0.07544654661946348,destabilizing
+KHDRBS3,SPDYE3,0.07648078752154348,destabilizing
+KHDRBS3,DMD,0.19688491236745878,destabilizing
+KHDRBS3,MCU,0.10455713445584043,destabilizing
+KHDRBS3,SSH2,0.10956554167288146,destabilizing
+KHDRBS3,DOCK3,0.14045064281188016,destabilizing
+KHDRBS3,HS6ST3,0.11106189420119202,destabilizing
+KHDRBS3,LPP,0.15199629532721162,destabilizing
+KHDRBS3,STAG1,0.10107518251209983,destabilizing
+KHDRBS3,CAPZA2,0.11827319470565732,destabilizing
+KHDRBS3,ADGRL3,0.08107308346087443,destabilizing
+KHDRBS3,PHACTR1,0.0636299572491775,destabilizing
+KHDRBS3,UBE2R2,0.12127465430308237,destabilizing
+KHDRBS3,GTF2IRD1,0.1192084161833725,destabilizing
+KHDRBS3,CCBE1,0.059558818825560744,destabilizing
+KHDRBS3,TTC28,0.09955820809534248,destabilizing
+KHDRBS3,SBNO1,0.06140449998648308,destabilizing
+KHDRBS3,RIMS2,0.07592340561747629,destabilizing
+KHDRBS3,TRIO,0.05936169460857743,destabilizing
+KHDRBS3,BTBD9,0.13544991852403154,destabilizing
+KHDRBS3,CNGB1,0.14922534537658183,destabilizing
+KHDRBS3,FMN2,0.09128862893025855,destabilizing
+KHDRBS3,ENSG00000228222,0.20098527488500273,destabilizing
+KHDRBS3,PRKN,0.17815088891558417,destabilizing
+KHDRBS3,RASA2,0.12936210951044005,destabilizing
+KHDRBS3,PPP1R12B,0.11691152287335171,destabilizing
+KHDRBS3,FRMD4A,0.08833002182341278,destabilizing
+KHDRBS3,SEMA6D,0.10444399814063435,destabilizing
+KHDRBS3,WIPF2,0.13843276701606005,destabilizing
+KHDRBS3,DLEU1,0.16883812003330467,destabilizing
+KHDRBS3,TSHZ2,0.06929584545737505,destabilizing
+KHDRBS3,MED13L,0.0663850331514405,destabilizing
+KHDRBS3,KAZN,0.11269149971583163,destabilizing
+KHDRBS3,KANSL1,0.07893079076681067,destabilizing
+KHDRBS3,FRMD5,0.11045015443427644,destabilizing
+KHDRBS3,LINC00174,0.12638976351015696,destabilizing
+KHDRBS3,PPM1E,0.10801642121707832,destabilizing
+KHDRBS3,ARL3,0.07426089336928068,destabilizing
+KHDRBS3,MBD5,0.10715086367663476,destabilizing
+KHDRBS3,ELAVL3,0.11099034801456226,destabilizing
+KHDRBS3,SLIT2,0.1272894356747243,destabilizing
+KHDRBS3,SLC8A1,0.06415043081579422,destabilizing
+KHDRBS3,CLASP1,0.10615569472072987,destabilizing
+KHDRBS3,UNC5C,0.13806345482356108,destabilizing
+KHDRBS3,NEGR1,0.14707669377183225,destabilizing
+KHDRBS3,ENOX1,0.16362406648409727,destabilizing
+KHDRBS3,SCUBE1,0.07268644451873062,destabilizing
+KHDRBS3,GPHN,0.10759398716724937,destabilizing
+KHDRBS3,NAV3,0.12492001599356325,destabilizing
+KHDRBS3,TOMM22,0.13595148420358188,destabilizing
+KHDRBS3,MAGI2,0.05693432708937759,destabilizing
+KHDRBS3,LSAMP,0.0725837165303634,destabilizing
+KHDRBS3,AKAP6,0.1469984615323945,destabilizing
+KHDRBS3,TMED2,0.08221092045189807,destabilizing
+KHDRBS3,ZBTB20,0.1035254806631007,destabilizing
+KHDRBS3,GRIK2,0.11294967572859496,destabilizing
+KHDRBS3,SOX5,0.10664831961820322,destabilizing
+KHDRBS3,LRRC37A3,0.15836329103913405,destabilizing
+KHDRBS3,EYS,0.0891623747787298,destabilizing
+KHDRBS3,ARID1B,0.09777763439222095,destabilizing
+KHDRBS3,PRKCE,0.09397024532171734,destabilizing
+KHDRBS3,RBFOX1,-0.06694624343005104,stabilizing
+KHDRBS3,SDK1,0.07789453299686133,destabilizing
+KHDRBS3,NRG1,0.067975145657604,destabilizing
+KHDRBS3,MLLT3,0.18250836301664383,destabilizing
+KHDRBS3,ADGRB3,0.07043262108960043,destabilizing
+KHDRBS3,ROBO1,0.09026786608284572,destabilizing
+KHDRBS3,SYPL1,0.06134180333647837,destabilizing
+KHDRBS3,PTPRD,0.097520349507325,destabilizing
+KHDRBS3,FAM155A,0.17515746014109707,destabilizing
+KHDRBS3,LARP1B,0.13913744395490818,destabilizing
+KHSRP,CENPP,0.1224098933669183,destabilizing
+KHSRP,KCNB2,0.0924555596834182,destabilizing
+KHSRP,ALK,0.13513270058782448,destabilizing
+KHSRP,MAGI3,0.07182117149513703,destabilizing
+KHSRP,DMD,0.09123547306093771,destabilizing
+KHSRP,MCU,0.07852781265028996,destabilizing
+KHSRP,FRMD5,0.06700010474336193,destabilizing
+KHSRP,SLIT2,0.08339510029213454,destabilizing
+KHSRP,AKAP6,0.07103313409280106,destabilizing
+KHSRP,MLLT3,0.09084892000638732,destabilizing
+KHSRP,LARP1B,0.06188642887105391,destabilizing
+TIAL1,TRERF1,0.09805079145849376,destabilizing
+TIAL1,SORCS1,0.06617641030420594,destabilizing
+TIAL1,PDE3A,0.12245640675880125,destabilizing
+TIAL1,UNC79,0.11136305594869896,destabilizing
+TIAL1,DOC2B,0.0855008455939652,destabilizing
+TIAL1,TMTC2,0.09580442816525091,destabilizing
+TIAL1,KALRN,0.07831704338038799,destabilizing
+TIAL1,MTMR7,0.10851719399616129,destabilizing
+TIAL1,EIF4E,0.10639744587514426,destabilizing
+TIAL1,EPB41L4B,0.06341781331470864,destabilizing
+TIAL1,LRRTM4,0.07664882230294946,destabilizing
+TIAL1,FRY,0.11162175684750837,destabilizing
+TIAL1,MACROD2,0.07774358275078058,destabilizing
+TIAL1,SHANK2,0.15262222917425367,destabilizing
+TIAL1,CDK12,0.1220544571918559,destabilizing
+TIAL1,MPHOSPH8,0.0790976432790773,destabilizing
+TIAL1,UBR3,0.07779713398669648,destabilizing
+TIAL1,DLG2,0.06670376644371405,destabilizing
+TIAL1,CHST12,0.17191416102844873,destabilizing
+TIAL1,EML5,0.11289545216279,destabilizing
+TIAL1,PSME4,0.10711952825399254,destabilizing
+TIAL1,TMEM106B,0.12288005215191604,destabilizing
+TIAL1,EPHA5,0.0940404759915978,destabilizing
+TIAL1,KCNB2,0.11861140955735912,destabilizing
+TIAL1,ZNF83,0.07398765777120836,destabilizing
+TIAL1,SOX6,0.06828049138694582,destabilizing
+TIAL1,ZNF521,0.09304945965149625,destabilizing
+TIAL1,NOVA1,0.12489628350893407,destabilizing
+TIAL1,CCNY,0.08969464948390889,destabilizing
+TIAL1,EPB41L5,0.05579797817747257,destabilizing
+TIAL1,GPR158,0.07393585157329854,destabilizing
+TIAL1,NCOA2,0.08252046843884568,destabilizing
+TIAL1,ALK,0.14616675356715766,destabilizing
+TIAL1,SIK3,0.0916647792351936,destabilizing
+TIAL1,CPEB3,0.11684243101046633,destabilizing
+TIAL1,XKR6,0.10709801643943385,destabilizing
+TIAL1,CADPS,0.06650159711023347,destabilizing
+TIAL1,TCF20,0.10203518257790495,destabilizing
+TIAL1,EXOC6B,0.13114083520601943,destabilizing
+TIAL1,MAGI3,0.09332358386694913,destabilizing
+TIAL1,INPP4B,0.06527880595163109,destabilizing
+TIAL1,DMD,0.12829812267858945,destabilizing
+TIAL1,MCU,0.08533152464723026,destabilizing
+TIAL1,SSH2,0.07566297252657402,destabilizing
+TIAL1,DOCK3,0.09942777681785307,destabilizing
+TIAL1,LPP,0.10585120184969116,destabilizing
+TIAL1,CAPZA2,0.0802500338277097,destabilizing
+TIAL1,UBE2R2,0.07836710388181059,destabilizing
+TIAL1,GTF2IRD1,0.06752188177168342,destabilizing
+TIAL1,BTBD9,0.0841599965058956,destabilizing
+TIAL1,CNGB1,0.11434816723043262,destabilizing
+TIAL1,ENSG00000228222,0.20228837452283374,destabilizing
+TIAL1,PRKN,0.12925900012903538,destabilizing
+TIAL1,RASA2,0.09463887503909893,destabilizing
+TIAL1,FRMD4A,0.0603028505318876,destabilizing
+TIAL1,SEMA6D,0.06552132249257608,destabilizing
+TIAL1,WIPF2,0.08086279180930486,destabilizing
+TIAL1,TSHZ2,0.05600726896229708,destabilizing
+TIAL1,FRMD5,0.06812947561757654,destabilizing
+TIAL1,LINC00174,0.0724198685994053,destabilizing
+TIAL1,PPM1E,0.08522258846338952,destabilizing
+TIAL1,MBD5,0.07812377637563983,destabilizing
+TIAL1,ELAVL3,0.06753632649277169,destabilizing
+TIAL1,SLIT2,0.1112214565197603,destabilizing
+TIAL1,UNC5C,0.07991133947440539,destabilizing
+TIAL1,NEGR1,0.08466006869093384,destabilizing
+TIAL1,GPHN,0.07616951040627597,destabilizing
+TIAL1,NAV3,0.10332931606973733,destabilizing
+TIAL1,TOMM22,0.10746642357732232,destabilizing
+TIAL1,AKAP6,0.09200546780527746,destabilizing
+TIAL1,ZBTB20,0.07763823425779141,destabilizing
+TIAL1,GRIK2,0.07818760706899067,destabilizing
+TIAL1,LRRC37A3,0.09423576861043083,destabilizing
+TIAL1,EYS,0.06166130502832479,destabilizing
+TIAL1,MLLT3,0.15904863758015506,destabilizing
+TIAL1,ROBO1,0.08658627367418363,destabilizing
+TIAL1,PTPRD,0.07968378425751853,destabilizing
+TIAL1,FAM155A,0.15407382629201236,destabilizing
+TIAL1,LARP1B,0.09127076670404265,destabilizing
+ZFP36L2,TRERF1,0.12108256651675184,destabilizing
+ZFP36L2,SORCS1,0.07673092790467315,destabilizing
+ZFP36L2,PDE3A,0.11700331932039103,destabilizing
+ZFP36L2,UNC79,0.1157925531000179,destabilizing
+ZFP36L2,TMTC2,0.09823770818949785,destabilizing
+ZFP36L2,MTMR7,0.08408653471377672,destabilizing
+ZFP36L2,CACNA1B,0.06107824811753463,destabilizing
+ZFP36L2,FRY,0.11764440691750798,destabilizing
+ZFP36L2,MACROD2,0.08418003364253746,destabilizing
+ZFP36L2,SHANK2,0.12221061769921435,destabilizing
+ZFP36L2,CDK12,0.10541404765102726,destabilizing
+ZFP36L2,MPHOSPH8,0.0806125457655206,destabilizing
+ZFP36L2,DIP2C,0.07113531481490495,destabilizing
+ZFP36L2,CHST12,0.13220519231126218,destabilizing
+ZFP36L2,EML5,0.08424545509515642,destabilizing
+ZFP36L2,CENPP,0.12840212963668207,destabilizing
+ZFP36L2,PSME4,0.07306113524455424,destabilizing
+ZFP36L2,TMEM106B,0.10740651605443291,destabilizing
+ZFP36L2,EPHA5,0.07337036342885814,destabilizing
+ZFP36L2,KCNB2,0.08667312530197224,destabilizing
+ZFP36L2,ZNF83,0.07928805538176825,destabilizing
+ZFP36L2,NOVA1,0.0934413374103743,destabilizing
+ZFP36L2,CCNY,0.08344714086196943,destabilizing
+ZFP36L2,GPR158,0.09167823523496368,destabilizing
+ZFP36L2,NCOA2,0.07106511519038437,destabilizing
+ZFP36L2,SIK3,0.0795758597707648,destabilizing
+ZFP36L2,XKR6,0.09685423230204529,destabilizing
+ZFP36L2,EXOC6B,0.13546627097722744,destabilizing
+ZFP36L2,MAGI3,0.10963946191460539,destabilizing
+ZFP36L2,SPDYE3,0.08003922408030226,destabilizing
+ZFP36L2,DMD,0.13894483166828278,destabilizing
+ZFP36L2,MCU,0.07792164094382334,destabilizing
+ZFP36L2,SSH2,0.07559109684692905,destabilizing
+ZFP36L2,DOCK3,0.1233330567734994,destabilizing
+ZFP36L2,LPP,0.08924211595922535,destabilizing
+ZFP36L2,STAG1,0.06356386471870822,destabilizing
+ZFP36L2,CAPZA2,0.08037450945152325,destabilizing
+ZFP36L2,UBE2R2,0.08542759699616756,destabilizing
+ZFP36L2,GTF2IRD1,0.07861297759010705,destabilizing
+ZFP36L2,FMN2,0.06547260947075949,destabilizing
+ZFP36L2,ENSG00000228222,0.12107761978790063,destabilizing
+ZFP36L2,PRKN,0.11539584092212361,destabilizing
+ZFP36L2,RASA2,0.06557556506523403,destabilizing
+ZFP36L2,FRMD4A,0.05544175005870399,destabilizing
+ZFP36L2,SEMA6D,0.06489254041803655,destabilizing
+ZFP36L2,FRMD5,0.06358296044833935,destabilizing
+ZFP36L2,LINC00174,0.06895529603188143,destabilizing
+ZFP36L2,PPM1E,0.08393590977833712,destabilizing
+ZFP36L2,MBD5,0.07516733201849621,destabilizing
+ZFP36L2,ELAVL3,0.06869693246769158,destabilizing
+ZFP36L2,SLIT2,0.10408837523465199,destabilizing
+ZFP36L2,UNC5C,0.07766500643682582,destabilizing
+ZFP36L2,NEGR1,0.11060692737708512,destabilizing
+ZFP36L2,GPHN,0.0753888107882845,destabilizing
+ZFP36L2,NAV3,0.08791296498956726,destabilizing
+ZFP36L2,TOMM22,0.08188769749113964,destabilizing
+ZFP36L2,AKAP6,0.0974298727024502,destabilizing
+ZFP36L2,ZBTB20,0.08040954300537916,destabilizing
+ZFP36L2,GRIK2,0.06677060034583229,destabilizing
+ZFP36L2,SOX5,0.0726570978941424,destabilizing
+ZFP36L2,LRRC37A3,0.10548118692842598,destabilizing
+ZFP36L2,MLLT3,0.08879316129012732,destabilizing
+ZFP36L2,FMN1,0.05953481921276492,destabilizing
+ZFP36L2,PTPRD,0.06408488348150128,destabilizing
+ZFP36L2,LARP1B,0.08868592724390711,destabilizing
+CPEB3,CPEB3,-0.2671986301030271,stabilizing
+CPEB4,TRERF1,0.09980177544550839,destabilizing
+CPEB4,SORCS1,0.06282558831700329,destabilizing
+CPEB4,PDE3A,0.10678513749842142,destabilizing
+CPEB4,UNC79,0.07708721437779856,destabilizing
+CPEB4,DOC2B,0.06981541615110026,destabilizing
+CPEB4,MTMR7,0.1077010257953282,destabilizing
+CPEB4,EPB41L4B,0.060470607227456986,destabilizing
+CPEB4,SIRPA,0.10286358670535561,destabilizing
+CPEB4,FRY,0.09810380297882507,destabilizing
+CPEB4,MACROD2,0.06958608838812286,destabilizing
+CPEB4,RFX7,0.11981150910079046,destabilizing
+CPEB4,EML5,0.08354081063838327,destabilizing
+CPEB4,PSME4,0.06909212060856314,destabilizing
+CPEB4,TMEM106B,0.0775505268591561,destabilizing
+CPEB4,EPHA5,0.07720751786451042,destabilizing
+CPEB4,ZNF83,0.06944470793333032,destabilizing
+CPEB4,NCOA2,0.06895949388219648,destabilizing
+CPEB4,IFT172,0.07458626437183508,destabilizing
+CPEB4,SIK3,0.08224347617482959,destabilizing
+CPEB4,XKR6,0.08919633388290198,destabilizing
+CPEB4,EXOC6B,0.10951245461165046,destabilizing
+CPEB4,MAGI3,0.0797158069358072,destabilizing
+CPEB4,SPDYE3,0.06976648104474216,destabilizing
+CPEB4,DMD,0.13144584119172945,destabilizing
+CPEB4,MCU,0.06768533194569044,destabilizing
+CPEB4,LPP,0.10096064691090138,destabilizing
+CPEB4,GTF2IRD1,0.08434696967098208,destabilizing
+CPEB4,CNGB1,0.09734591435251767,destabilizing
+CPEB4,FMN2,0.08597453997160157,destabilizing
+CPEB4,PRKN,0.1300473263280628,destabilizing
+CPEB4,RASA2,0.06850495207050633,destabilizing
+CPEB4,KAZN,0.10121371847333313,destabilizing
+CPEB4,LINC00174,0.07340439979241685,destabilizing
+CPEB4,SLIT2,0.12458281459874436,destabilizing
+CPEB4,UNC5C,0.0781263017622225,destabilizing
+CPEB4,NEGR1,0.07740873358902547,destabilizing
+CPEB4,GPHN,0.06342745626304634,destabilizing
+CPEB4,ZBTB20,0.07408736941201835,destabilizing
+CPEB4,LRRC37A3,0.10096498328349887,destabilizing
+CPEB4,EYS,0.05905133100383057,destabilizing
+CPEB4,MLLT3,0.10561695394756607,destabilizing
+CPEB4,ROBO1,0.07242480381430257,destabilizing
+CPEB4,LARP1B,0.0842278116791711,destabilizing
+PUM1,DLG2,0.062022410495528035,destabilizing
+PUM1,IFT172,0.0702744090356348,destabilizing
+PUM1,MAGI3,0.07175485009483636,destabilizing
+PUM1,DMD,0.07451899191810767,destabilizing
+PUM1,SSH2,0.0631416874951458,destabilizing
+PUM1,DOCK3,0.094356326609472,destabilizing
+PUM1,LRRC37A3,0.08081978922370381,destabilizing
+PUM1,LARP1B,0.06819512198788277,destabilizing
+PUM2,CDK12,0.09318759651184771,destabilizing
+PUM2,EML5,0.08231556303443835,destabilizing
+PUM2,CENPP,0.14614837970210443,destabilizing
+PUM2,PUM2,-0.37934055613401985,stabilizing
+PUM2,ALK,0.1523917225758456,destabilizing
+PUM2,EXOC6B,0.08492088711615446,destabilizing
+PUM2,DMD,0.07985682548992289,destabilizing
+PUM2,WIPF2,0.08734661177587236,destabilizing
+PUM2,ZBTB20,0.0724410467298846,destabilizing
+PUM2,MLLT3,0.09283556286796296,destabilizing
+STAU1,TRERF1,0.17906313010110567,destabilizing
+STAU1,SORCS1,0.10667423113957088,destabilizing
+STAU1,COPA,0.06111345154091746,destabilizing
+STAU1,FCHSD2,0.07865316602016004,destabilizing
+STAU1,PDE3A,0.1671060432698347,destabilizing
+STAU1,UNC79,0.17137193185595564,destabilizing
+STAU1,DOC2B,0.12279803213062156,destabilizing
+STAU1,TMTC2,0.1487111925808709,destabilizing
+STAU1,KALRN,0.12073853348013845,destabilizing
+STAU1,CHD1,0.09653297106870876,destabilizing
+STAU1,UBE2E2,0.06579145766137998,destabilizing
+STAU1,PPARD,0.08351264712960184,destabilizing
+STAU1,BRAF,0.055101030303389864,destabilizing
+STAU1,RYR2,0.1692550850908079,destabilizing
+STAU1,MTMR7,0.17189125070570074,destabilizing
+STAU1,EIF4E,0.16416256588391032,destabilizing
+STAU1,SOX11,0.07571978693701507,destabilizing
+STAU1,EPB41L4B,0.10465543199465298,destabilizing
+STAU1,CACNA1B,0.11673933908016332,destabilizing
+STAU1,LRRTM4,0.11843201182591231,destabilizing
+STAU1,SIRPA,0.15746367933082586,destabilizing
+STAU1,PTEN,0.08673921224615404,destabilizing
+STAU1,FRY,0.1687353472573027,destabilizing
+STAU1,MACROD2,0.16893278012278126,destabilizing
+STAU1,FOXN3,0.06591709536570692,destabilizing
+STAU1,SHANK2,0.21951162797244703,destabilizing
+STAU1,CDK12,0.2281358235985523,destabilizing
+STAU1,RFX7,0.1439084112620242,destabilizing
+STAU1,UBR5,0.08972825062990615,destabilizing
+STAU1,JARID2,0.08473490901904604,destabilizing
+STAU1,MPHOSPH8,0.13144080527700347,destabilizing
+STAU1,DIP2C,0.10585675825662877,destabilizing
+STAU1,ZNF423,0.06732078607613076,destabilizing
+STAU1,UBR3,0.10836197988162792,destabilizing
+STAU1,MGAT5,0.06448322622189735,destabilizing
+STAU1,DLG2,0.11510159621557478,destabilizing
+STAU1,CHST12,0.2784319815824516,destabilizing
+STAU1,EML5,0.18068896290362751,destabilizing
+STAU1,CENPP,0.19380718520771403,destabilizing
+STAU1,PSME4,0.16336105829223938,destabilizing
+STAU1,TMEM106B,0.14828234926522288,destabilizing
+STAU1,EPHA5,0.10893935819000007,destabilizing
+STAU1,KCNB2,0.15575063929832328,destabilizing
+STAU1,ZNF83,0.11500991175418526,destabilizing
+STAU1,SOX6,0.0740380615206838,destabilizing
+STAU1,ZNF521,0.1319077131367733,destabilizing
+STAU1,PLEKHA5,0.09818310994152567,destabilizing
+STAU1,NOVA1,0.18919630130172624,destabilizing
+STAU1,CCNY,0.15742642596021306,destabilizing
+STAU1,ARIH1,0.14112903488028272,destabilizing
+STAU1,EPB41L5,0.11120583095169741,destabilizing
+STAU1,GPR158,0.16288421546136336,destabilizing
+STAU1,NCOA2,0.10777015430295506,destabilizing
+STAU1,ALK,0.13498813424060374,destabilizing
+STAU1,ACACA,0.08631613390381138,destabilizing
+STAU1,IFT172,0.1457668753426052,destabilizing
+STAU1,CCNT1,0.09027317361542839,destabilizing
+STAU1,DTWD2,0.18637069813742901,destabilizing
+STAU1,SIK3,0.1285645654707455,destabilizing
+STAU1,CPEB3,0.18098585316611868,destabilizing
+STAU1,CADM2,0.08352612591021139,destabilizing
+STAU1,XKR6,0.19340984972609854,destabilizing
+STAU1,RMND5A,0.06259943666704283,destabilizing
+STAU1,CADPS,0.0857642396640679,destabilizing
+STAU1,FGF13,0.0593549218414877,destabilizing
+STAU1,TCF20,0.17737558461907224,destabilizing
+STAU1,CDKAL1,0.06782318475176394,destabilizing
+STAU1,DGKI,0.10662941006921381,destabilizing
+STAU1,EXOC6B,0.18766923625339843,destabilizing
+STAU1,MAGI3,0.14072624900941583,destabilizing
+STAU1,SBF2,0.08689093991171985,destabilizing
+STAU1,INPP4B,0.14847399719716461,destabilizing
+STAU1,PTPRS,0.15229270613294868,destabilizing
+STAU1,CBFA2T2,0.10133915567916449,destabilizing
+STAU1,SPDYE3,0.12842830588276075,destabilizing
+STAU1,TMEM178B,0.08002558526404649,destabilizing
+STAU1,DMD,0.23437908821770267,destabilizing
+STAU1,MCU,0.13594572452268575,destabilizing
+STAU1,SSH2,0.11005497191621604,destabilizing
+STAU1,DOCK3,0.1825000440830059,destabilizing
+STAU1,HS6ST3,0.17057713389360654,destabilizing
+STAU1,LPP,0.15782849034390756,destabilizing
+STAU1,STAG1,0.11523810187392318,destabilizing
+STAU1,CAPZA2,0.15978102165022562,destabilizing
+STAU1,ADGRL3,0.07650547173867867,destabilizing
+STAU1,PHACTR1,0.06202166985422303,destabilizing
+STAU1,UBE2R2,0.17154288750155364,destabilizing
+STAU1,GTF2IRD1,0.1509382441565033,destabilizing
+STAU1,CCBE1,0.07475712088694271,destabilizing
+STAU1,TTC28,0.10677633149791693,destabilizing
+STAU1,SBNO1,0.06419194318931398,destabilizing
+STAU1,RIMS2,0.08579553283756924,destabilizing
+STAU1,IGF1R,0.060872795793883216,destabilizing
+STAU1,TRIO,0.06242076561189917,destabilizing
+STAU1,KCND2,0.06486787558928192,destabilizing
+STAU1,BTBD9,0.14622132203396948,destabilizing
+STAU1,CNGB1,0.17855285660511286,destabilizing
+STAU1,FMN2,0.12559782352915486,destabilizing
+STAU1,ENSG00000228222,0.17756717646196785,destabilizing
+STAU1,ATXN1,0.06501854817654905,destabilizing
+STAU1,PRKN,0.19245763786664402,destabilizing
+STAU1,RASA2,0.15012902221856603,destabilizing
+STAU1,PPP1R12B,0.1002413540523904,destabilizing
+STAU1,FRMD4A,0.10118189587083651,destabilizing
+STAU1,CAMK1D,0.06482687569737783,destabilizing
+STAU1,PARD3,0.053242517138758674,destabilizing
+STAU1,SEMA6D,0.12162997911870238,destabilizing
+STAU1,WIPF2,0.1492276581566547,destabilizing
+STAU1,DLEU1,0.18837141318624856,destabilizing
+STAU1,TSHZ2,0.09798155358072314,destabilizing
+STAU1,MED13L,0.09633853856005979,destabilizing
+STAU1,KAZN,0.151680880964553,destabilizing
+STAU1,KANSL1,0.07765265490392477,destabilizing
+STAU1,FRMD5,0.15066516699757299,destabilizing
+STAU1,LINC00174,0.12386471848160467,destabilizing
+STAU1,PPM1E,0.14868475796745098,destabilizing
+STAU1,ARL3,0.08972724200368078,destabilizing
+STAU1,MBD5,0.10760293655657406,destabilizing
+STAU1,ELAVL3,0.13760491123809906,destabilizing
+STAU1,SLIT2,0.1858800869864348,destabilizing
+STAU1,CLASP1,0.0829161516838953,destabilizing
+STAU1,UNC5C,0.12918212077797758,destabilizing
+STAU1,CACNA2D3,-0.061803226344045,stabilizing
+STAU1,RC3H1,0.1091025471500096,destabilizing
+STAU1,NEGR1,0.13228948942574856,destabilizing
+STAU1,ENOX1,0.18379843685561884,destabilizing
+STAU1,SCUBE1,0.06489341531937286,destabilizing
+STAU1,GPHN,0.10059003146634234,destabilizing
+STAU1,NAV3,0.14525683007726148,destabilizing
+STAU1,EBF1,0.06339664271770241,destabilizing
+STAU1,TOMM22,0.1685182326263581,destabilizing
+STAU1,MBNL2,0.0790174462062726,destabilizing
+STAU1,ANKFN1,0.05725751863840793,destabilizing
+STAU1,MAGI2,0.07839377495864545,destabilizing
+STAU1,LSAMP,0.08319334350811211,destabilizing
+STAU1,AKAP6,0.16405090184420584,destabilizing
+STAU1,TMED2,0.10842821475744709,destabilizing
+STAU1,ZBTB20,0.12754175109036142,destabilizing
+STAU1,GRIK2,0.1362915887965353,destabilizing
+STAU1,SOX5,0.09026764218346532,destabilizing
+STAU1,LRRC37A3,0.19364245760039783,destabilizing
+STAU1,EYS,0.1050075187105036,destabilizing
+STAU1,ARID1B,0.08394630303465006,destabilizing
+STAU1,PRKCE,0.09655525227876995,destabilizing
+STAU1,RBFOX1,-0.09754743313749491,stabilizing
+STAU1,SDK1,0.08242170473958751,destabilizing
+STAU1,MLLT3,0.19262347205756994,destabilizing
+STAU1,FMN1,0.08052509159199284,destabilizing
+STAU1,ADGRB3,0.08390152007293458,destabilizing
+STAU1,ROBO1,0.12753288453775863,destabilizing
+STAU1,SYPL1,0.07066495975140998,destabilizing
+STAU1,PTPRD,0.12545438244486176,destabilizing
+STAU1,FAM155A,0.14025497632097067,destabilizing
+STAU1,LARP1B,0.12939402110683826,destabilizing
+STAU2,TRERF1,0.08847366478147801,destabilizing
+STAU2,SORCS1,0.06629407803941628,destabilizing
+STAU2,PDE3A,0.12820575287483946,destabilizing
+STAU2,UNC79,0.11000771854696341,destabilizing
+STAU2,DOC2B,0.062447046216413754,destabilizing
+STAU2,TMTC2,0.12330411513744385,destabilizing
+STAU2,RYR2,0.13941956516768902,destabilizing
+STAU2,MTMR7,0.08726544757074296,destabilizing
+STAU2,EPB41L4B,0.06116204722294149,destabilizing
+STAU2,CACNA1B,0.058657266288466466,destabilizing
+STAU2,LRRTM4,0.060610737791947616,destabilizing
+STAU2,SIRPA,0.0990010484456862,destabilizing
+STAU2,FRY,0.10178313083218486,destabilizing
+STAU2,MACROD2,0.12100741774499628,destabilizing
+STAU2,SHANK2,0.12372330759532527,destabilizing
+STAU2,CDK12,0.12912950107920865,destabilizing
+STAU2,UBR5,0.06940666653222483,destabilizing
+STAU2,JARID2,0.053635883011313695,destabilizing
+STAU2,MPHOSPH8,0.07593620090639518,destabilizing
+STAU2,DIP2C,0.08600037297371285,destabilizing
+STAU2,UBR3,0.07125840847443843,destabilizing
+STAU2,DLG2,0.0678044032206622,destabilizing
+STAU2,EML5,0.11233933175436349,destabilizing
+STAU2,PSME4,0.09882928163375507,destabilizing
+STAU2,TMEM106B,0.0922396896026284,destabilizing
+STAU2,EPHA5,0.09132781457007023,destabilizing
+STAU2,KCNB2,0.1008269572915906,destabilizing
+STAU2,ZNF521,0.07755612880919822,destabilizing
+STAU2,NOVA1,0.11012405509540056,destabilizing
+STAU2,CCNY,0.13410605251968302,destabilizing
+STAU2,ARIH1,0.08384070369903261,destabilizing
+STAU2,EPB41L5,0.059354935847069974,destabilizing
+STAU2,GPR158,0.09706538611567941,destabilizing
+STAU2,NCOA2,0.0729802642902667,destabilizing
+STAU2,ALK,0.10199512509108928,destabilizing
+STAU2,IFT172,0.09293416099676696,destabilizing
+STAU2,CCNT1,0.06567621430884307,destabilizing
+STAU2,SIK3,0.08242889201261268,destabilizing
+STAU2,CPEB3,0.10738511902365742,destabilizing
+STAU2,XKR6,0.10967354488435171,destabilizing
+STAU2,TCF20,0.1028841995182487,destabilizing
+STAU2,DGKI,0.08029838947908123,destabilizing
+STAU2,EXOC6B,0.12288360683608315,destabilizing
+STAU2,MAGI3,0.0959832124381851,destabilizing
+STAU2,INPP4B,0.0878674264056594,destabilizing
+STAU2,CBFA2T2,0.058251725415345686,destabilizing
+STAU2,SPDYE3,0.08320749292771433,destabilizing
+STAU2,DMD,0.1385458849904453,destabilizing
+STAU2,MCU,0.06659709276862368,destabilizing
+STAU2,SSH2,0.07004172673081942,destabilizing
+STAU2,DOCK3,0.11918247613171314,destabilizing
+STAU2,LPP,0.1226429146483643,destabilizing
+STAU2,STAG1,0.0800643118156107,destabilizing
+STAU2,UBE2R2,0.08616029768762666,destabilizing
+STAU2,GTF2IRD1,0.0815915360829945,destabilizing
+STAU2,CCBE1,0.054740654561590864,destabilizing
+STAU2,SBNO1,0.058601278690461236,destabilizing
+STAU2,BTBD9,0.09792221623511156,destabilizing
+STAU2,CNGB1,0.09494624717956851,destabilizing
+STAU2,FMN2,0.07222948880438242,destabilizing
+STAU2,ENSG00000228222,0.15177185067635932,destabilizing
+STAU2,PRKN,0.10180636362157364,destabilizing
+STAU2,RASA2,0.10538527211564923,destabilizing
+STAU2,FRMD4A,0.06520552569365558,destabilizing
+STAU2,SEMA6D,0.06395060081236208,destabilizing
+STAU2,WIPF2,0.07405832209568744,destabilizing
+STAU2,TSHZ2,0.06379232869859146,destabilizing
+STAU2,KAZN,0.07442115352714279,destabilizing
+STAU2,FRMD5,0.08632702315613432,destabilizing
+STAU2,LINC00174,0.061258606680646796,destabilizing
+STAU2,PPM1E,0.08117484938667228,destabilizing
+STAU2,MBD5,0.07206157855125325,destabilizing
+STAU2,ELAVL3,0.08871067889644073,destabilizing
+STAU2,SLIT2,0.11586251140461315,destabilizing
+STAU2,UNC5C,0.0958792848728284,destabilizing
+STAU2,GPHN,0.0769581855724874,destabilizing
+STAU2,NAV3,0.09679020772123027,destabilizing
+STAU2,TOMM22,0.08470695110245091,destabilizing
+STAU2,MAGI2,0.056114294883372696,destabilizing
+STAU2,LSAMP,0.054937987114078726,destabilizing
+STAU2,AKAP6,0.0820198047874418,destabilizing
+STAU2,ZBTB20,0.07738616123716267,destabilizing
+STAU2,GRIK2,0.0860576466909638,destabilizing
+STAU2,LRRC37A3,0.10200024699999012,destabilizing
+STAU2,SDK1,0.08212372549565886,destabilizing
+STAU2,MLLT3,0.11779936644215164,destabilizing
+STAU2,FMN1,0.06047276669976803,destabilizing
+STAU2,ROBO1,0.07348869483246036,destabilizing
+STAU2,PTPRD,0.07574690643155209,destabilizing
+STAU2,FAM155A,0.1010535168599385,destabilizing
+STAU2,LARP1B,0.08387138040257731,destabilizing
+UPF1,KCNB2,0.08564240941890415,destabilizing
+UPF2,TRERF1,0.11495019689368047,destabilizing
+UPF2,SORCS1,0.07759018852004562,destabilizing
+UPF2,UNC79,0.09526124502453354,destabilizing
+UPF2,UBE2E2,0.05850249077585802,destabilizing
+UPF2,MTMR7,0.12353892240878607,destabilizing
+UPF2,EIF4E,0.10437774354630844,destabilizing
+UPF2,LRRTM4,0.0581112031149767,destabilizing
+UPF2,MACROD2,0.07330789410031034,destabilizing
+UPF2,SHANK2,0.10487088327973575,destabilizing
+UPF2,CDK12,0.09272066310938765,destabilizing
+UPF2,MPHOSPH8,0.0644843789934093,destabilizing
+UPF2,DIP2C,0.0683486093827375,destabilizing
+UPF2,CHST12,0.14087264869856864,destabilizing
+UPF2,EML5,0.11074468761853591,destabilizing
+UPF2,PSME4,0.11262893571606221,destabilizing
+UPF2,KCNB2,0.0895821065596533,destabilizing
+UPF2,NOVA1,0.09407491047463892,destabilizing
+UPF2,CCNY,0.08542632525703618,destabilizing
+UPF2,ARIH1,0.06126520412788809,destabilizing
+UPF2,EPB41L5,0.057093367172316396,destabilizing
+UPF2,GPR158,0.08036482274641381,destabilizing
+UPF2,SIK3,0.07570477584136624,destabilizing
+UPF2,TCF20,0.09600111418253145,destabilizing
+UPF2,EXOC6B,0.11656218866731208,destabilizing
+UPF2,MAGI3,0.07847383144492413,destabilizing
+UPF2,SPDYE3,0.067528568443593,destabilizing
+UPF2,DMD,0.12860724417227848,destabilizing
+UPF2,MCU,0.08566944440478988,destabilizing
+UPF2,DOCK3,0.0820045492087953,destabilizing
+UPF2,HS6ST3,0.09068711256981905,destabilizing
+UPF2,GTF2IRD1,0.0586072894686413,destabilizing
+UPF2,CNGB1,0.10593314463758861,destabilizing
+UPF2,ENSG00000228222,0.12232349295845889,destabilizing
+UPF2,PRKN,0.11025536939958648,destabilizing
+UPF2,RASA2,0.06877558729846112,destabilizing
+UPF2,FRMD4A,0.0625966626391247,destabilizing
+UPF2,WIPF2,0.08742354214280598,destabilizing
+UPF2,LINC00174,0.07891102009068232,destabilizing
+UPF2,ELAVL3,0.07077745608323671,destabilizing
+UPF2,SLIT2,0.10065359779945411,destabilizing
+UPF2,UNC5C,0.08385430396789133,destabilizing
+UPF2,NAV3,0.09360243481225701,destabilizing
+UPF2,GRIK2,0.060309407842188155,destabilizing
+UPF2,LRRC37A3,0.10757397791705536,destabilizing
+UPF2,PRKCE,0.08765818662210398,destabilizing
+UPF2,MLLT3,0.09774979005731631,destabilizing
+UPF2,ROBO1,0.0703613791809604,destabilizing
+UPF2,LARP1B,0.0691012653072394,destabilizing
+UPF3B,TRERF1,0.10273347284487871,destabilizing
+UPF3B,UNC79,0.09390399959245424,destabilizing
+UPF3B,DOC2B,0.06068649700033719,destabilizing
+UPF3B,PPARD,0.0671949261671757,destabilizing
+UPF3B,MTMR7,0.09372762265015164,destabilizing
+UPF3B,EPB41L4B,0.06238518614446834,destabilizing
+UPF3B,LRRTM4,0.06932910887025884,destabilizing
+UPF3B,FRY,0.10080189609180562,destabilizing
+UPF3B,MACROD2,0.09175179546854098,destabilizing
+UPF3B,CDK12,0.09454219185456672,destabilizing
+UPF3B,RFX7,0.09546012443848223,destabilizing
+UPF3B,MPHOSPH8,0.07955508107515606,destabilizing
+UPF3B,DIP2C,0.06905894873087447,destabilizing
+UPF3B,CHST12,0.11519840310714989,destabilizing
+UPF3B,EML5,0.08317158088644212,destabilizing
+UPF3B,CENPP,0.1386693945337683,destabilizing
+UPF3B,TMEM106B,0.10853901635220356,destabilizing
+UPF3B,KCNB2,0.0882468000541905,destabilizing
+UPF3B,ZNF521,0.07580442197568958,destabilizing
+UPF3B,CCNY,0.09460687264587302,destabilizing
+UPF3B,ARIH1,0.06289781164563725,destabilizing
+UPF3B,EPB41L5,0.05571036018059246,destabilizing
+UPF3B,GPR158,0.08961846187666715,destabilizing
+UPF3B,ALK,0.12214810557149325,destabilizing
+UPF3B,IFT172,0.07685327380512486,destabilizing
+UPF3B,CCNT1,0.059316871009675386,destabilizing
+UPF3B,DTWD2,0.1510696071979053,destabilizing
+UPF3B,CPEB3,0.10440869670069429,destabilizing
+UPF3B,XKR6,0.10038345811615347,destabilizing
+UPF3B,DGKI,0.0717036156530807,destabilizing
+UPF3B,EXOC6B,0.11082288833815505,destabilizing
+UPF3B,MAGI3,0.07755075562740855,destabilizing
+UPF3B,INPP4B,0.06495573361337363,destabilizing
+UPF3B,DMD,0.11476722464651314,destabilizing
+UPF3B,SSH2,0.0722836673014703,destabilizing
+UPF3B,DOCK3,0.10103982367629717,destabilizing
+UPF3B,CAPZA2,0.07464656796642294,destabilizing
+UPF3B,ADGRL3,0.06609341432934238,destabilizing
+UPF3B,UBE2R2,0.0790411446752767,destabilizing
+UPF3B,PRKN,0.10751009650261971,destabilizing
+UPF3B,RASA2,0.07805861718886546,destabilizing
+UPF3B,WIPF2,0.07118630930714621,destabilizing
+UPF3B,FRMD5,0.0750940196459429,destabilizing
+UPF3B,LINC00174,0.07471978901624733,destabilizing
+UPF3B,MBD5,0.06811850374817563,destabilizing
+UPF3B,ELAVL3,0.07993168523752785,destabilizing
+UPF3B,SLIT2,0.13291195803276135,destabilizing
+UPF3B,CLASP1,0.07337017732436264,destabilizing
+UPF3B,UNC5C,0.08975638823280946,destabilizing
+UPF3B,NEGR1,0.0755720453324762,destabilizing
+UPF3B,NAV3,0.10703876574068773,destabilizing
+UPF3B,TMED2,0.06549497613423956,destabilizing
+UPF3B,ZBTB20,0.07255011871163948,destabilizing
+UPF3B,GRIK2,0.07120400837336284,destabilizing
+UPF3B,LRRC37A3,0.10720041831141669,destabilizing
+UPF3B,RBFOX1,-0.05781418891270059,stabilizing
+UPF3B,MLLT3,0.09149976889055707,destabilizing
+UPF3B,PTPRD,0.056690729888086024,destabilizing
+UPF3B,LARP1B,0.06535841924988366,destabilizing
+SMG1,MACROD2,0.07086750948177797,destabilizing
+DIS3L2,TRERF1,0.08837991042264376,destabilizing
+DIS3L2,SORCS1,0.06399619688271693,destabilizing
+DIS3L2,PDE3A,0.09640668652310162,destabilizing
+DIS3L2,UNC79,0.09242007385770826,destabilizing
+DIS3L2,DOC2B,0.06490269480089894,destabilizing
+DIS3L2,TMTC2,0.07856473770813445,destabilizing
+DIS3L2,RYR2,0.12475421982900455,destabilizing
+DIS3L2,MTMR7,0.09214487512226567,destabilizing
+DIS3L2,MACROD2,0.068996679652712,destabilizing
+DIS3L2,SHANK2,0.10391705179200915,destabilizing
+DIS3L2,CDK12,0.08455420493011001,destabilizing
+DIS3L2,RFX7,0.1119720665256944,destabilizing
+DIS3L2,MPHOSPH8,0.07202330510300868,destabilizing
+DIS3L2,CHST12,0.13969309928763055,destabilizing
+DIS3L2,EML5,0.08057932110677422,destabilizing
+DIS3L2,PSME4,0.09154721550339553,destabilizing
+DIS3L2,ZNF521,0.07326986200686132,destabilizing
+DIS3L2,CCNY,0.09616031045339495,destabilizing
+DIS3L2,ARIH1,0.061137065670631985,destabilizing
+DIS3L2,GPR158,0.08186884393480233,destabilizing
+DIS3L2,NCOA2,0.06679350917183698,destabilizing
+DIS3L2,XKR6,0.08355888412045896,destabilizing
+DIS3L2,EXOC6B,0.08758643117547557,destabilizing
+DIS3L2,DMD,0.1210564030192465,destabilizing
+DIS3L2,LPP,0.10559081055870896,destabilizing
+DIS3L2,STAG1,0.06931782809347099,destabilizing
+DIS3L2,PHACTR1,0.06014863500145742,destabilizing
+DIS3L2,GTF2IRD1,0.057831256436598956,destabilizing
+DIS3L2,BTBD9,0.0770311741987768,destabilizing
+DIS3L2,CNGB1,0.08880396718127066,destabilizing
+DIS3L2,ENSG00000228222,0.15524943483028847,destabilizing
+DIS3L2,PRKN,0.10158621215353865,destabilizing
+DIS3L2,RASA2,0.06468934572285379,destabilizing
+DIS3L2,SEMA6D,0.05942376725566453,destabilizing
+DIS3L2,WIPF2,0.06893692745883821,destabilizing
+DIS3L2,FRMD5,0.0645442704615214,destabilizing
+DIS3L2,PPM1E,0.0817279107609809,destabilizing
+DIS3L2,MBD5,0.05813234152135872,destabilizing
+DIS3L2,ELAVL3,0.07072879088118951,destabilizing
+DIS3L2,SLIT2,0.09405996709955487,destabilizing
+DIS3L2,UNC5C,0.07283987246635094,destabilizing
+DIS3L2,RC3H1,0.06862189346466303,destabilizing
+DIS3L2,NEGR1,0.08039621288352643,destabilizing
+DIS3L2,GPHN,0.06665662391046297,destabilizing
+DIS3L2,LSAMP,0.0558088370591258,destabilizing
+DIS3L2,AKAP6,0.07215188458865583,destabilizing
+DIS3L2,MLLT3,0.08986952902528618,destabilizing
+DIS3L2,ADGRB3,0.06984719098764912,destabilizing
+DIS3L2,PTPRD,0.06593884229425163,destabilizing
+XRN1,GPR158,0.07348234316702479,destabilizing
+XRN1,MAGI3,0.06739699755084762,destabilizing
+XRN1,DMD,0.10222796563129441,destabilizing
+XRN1,RASA2,0.07483733312130099,destabilizing
+XRN1,FRMD5,0.0812096739456312,destabilizing
+XRN1,UNC5C,0.06278503006265199,destabilizing
+XRN1,MLLT3,0.08242045204564441,destabilizing
+XRN1,LARP1B,0.06948691974041774,destabilizing
+XRN2,TRERF1,0.08636547785217852,destabilizing
+XRN2,PDE3A,0.0998273565701556,destabilizing
+XRN2,UNC79,0.08118090817102674,destabilizing
+XRN2,DOC2B,0.06268568268642959,destabilizing
+XRN2,TMTC2,0.07655255220305052,destabilizing
+XRN2,CACNA1B,0.061843132901061,destabilizing
+XRN2,FRY,0.09268926964827132,destabilizing
+XRN2,MACROD2,0.07903645456378088,destabilizing
+XRN2,SHANK2,0.1251526688152679,destabilizing
+XRN2,CDK12,0.12482758957526044,destabilizing
+XRN2,DLG2,0.06500507513100458,destabilizing
+XRN2,CHST12,0.1452481318508315,destabilizing
+XRN2,PSME4,0.073368465068643,destabilizing
+XRN2,TMEM106B,0.11239213538995192,destabilizing
+XRN2,ZNF521,0.0804023884006494,destabilizing
+XRN2,PLEKHA5,0.06458363093154082,destabilizing
+XRN2,ARIH1,0.06554903667512718,destabilizing
+XRN2,EPB41L5,0.06040920985365302,destabilizing
+XRN2,IFT172,0.07645914366868613,destabilizing
+XRN2,CCNT1,0.0596898232511033,destabilizing
+XRN2,SIK3,0.07859214663041138,destabilizing
+XRN2,XKR6,0.0948486236012232,destabilizing
+XRN2,CDKAL1,0.07912579126484656,destabilizing
+XRN2,DGKI,0.07683731538584963,destabilizing
+XRN2,EXOC6B,0.10749794027189487,destabilizing
+XRN2,MAGI3,0.09898157808462749,destabilizing
+XRN2,PTPRS,0.12397284821628808,destabilizing
+XRN2,SPDYE3,0.07549762343270704,destabilizing
+XRN2,DMD,0.10484579754614308,destabilizing
+XRN2,SSH2,0.0923507465455573,destabilizing
+XRN2,DOCK3,0.08733706719798073,destabilizing
+XRN2,HS6ST3,0.09026168034394706,destabilizing
+XRN2,STAG1,0.06621772995840607,destabilizing
+XRN2,UBE2R2,0.08782779768069005,destabilizing
+XRN2,GTF2IRD1,0.05984557624219921,destabilizing
+XRN2,SBNO1,0.059734440054559995,destabilizing
+XRN2,ENSG00000228222,0.13254675209146674,destabilizing
+XRN2,RASA2,0.08501965768511055,destabilizing
+XRN2,SEMA6D,0.07240907653520243,destabilizing
+XRN2,DLEU1,0.11078259400252669,destabilizing
+XRN2,FRMD5,0.06812786046344725,destabilizing
+XRN2,LINC00174,0.06322028322596188,destabilizing
+XRN2,MBD5,0.06982268564492819,destabilizing
+XRN2,ELAVL3,0.09713315865858575,destabilizing
+XRN2,SLIT2,0.09572190304481952,destabilizing
+XRN2,UNC5C,0.08686737656887752,destabilizing
+XRN2,NEGR1,0.08399428223364569,destabilizing
+XRN2,TOMM22,0.08542346040386058,destabilizing
+XRN2,ZBTB20,0.09445815315305198,destabilizing
+XRN2,SOX5,0.0730238732457323,destabilizing
+XRN2,LRRC37A3,0.08475004953223254,destabilizing
+XRN2,MLLT3,0.10958674770945523,destabilizing
+XRN2,PTPRD,0.06578633647653724,destabilizing
+XRN2,FAM155A,0.11878655838076468,destabilizing
+XRN2,LARP1B,0.08095326682748402,destabilizing
+EXOSC10,TRERF1,0.08446525669364215,destabilizing
+EXOSC10,UNC79,0.09807129122133852,destabilizing
+EXOSC10,TMTC2,0.09530630439938009,destabilizing
+EXOSC10,KALRN,0.06958466892892606,destabilizing
+EXOSC10,MTMR7,0.11961948642268486,destabilizing
+EXOSC10,CACNA1B,0.06924796106137528,destabilizing
+EXOSC10,PTEN,0.08599241684819257,destabilizing
+EXOSC10,FRY,0.08997571665726538,destabilizing
+EXOSC10,MACROD2,0.0687358949715396,destabilizing
+EXOSC10,SHANK2,0.12422270134462363,destabilizing
+EXOSC10,CDK12,0.1255134075964093,destabilizing
+EXOSC10,RFX7,0.10161893678068479,destabilizing
+EXOSC10,MPHOSPH8,0.08048138498753599,destabilizing
+EXOSC10,DLG2,0.07169706117901371,destabilizing
+EXOSC10,CHST12,0.13398838356084689,destabilizing
+EXOSC10,EML5,0.10679497649028358,destabilizing
+EXOSC10,CENPP,0.15705452234426281,destabilizing
+EXOSC10,TMEM106B,0.08630393833110765,destabilizing
+EXOSC10,SOX6,0.08277467831747927,destabilizing
+EXOSC10,ZNF521,0.09437930955359274,destabilizing
+EXOSC10,CCNY,0.0930492851432147,destabilizing
+EXOSC10,EPB41L5,0.06344471548765758,destabilizing
+EXOSC10,GPR158,0.07480218357757948,destabilizing
+EXOSC10,ALK,0.11297153532924166,destabilizing
+EXOSC10,IFT172,0.07593137396379958,destabilizing
+EXOSC10,DTWD2,0.1384647930778423,destabilizing
+EXOSC10,CPEB3,0.10963873076509506,destabilizing
+EXOSC10,DGKI,0.07513761519644854,destabilizing
+EXOSC10,MAGI3,0.08925426867426081,destabilizing
+EXOSC10,DMD,0.10887152397674976,destabilizing
+EXOSC10,SSH2,0.0772660405637974,destabilizing
+EXOSC10,DOCK3,0.08365576550463692,destabilizing
+EXOSC10,HS6ST3,0.09022111086569101,destabilizing
+EXOSC10,CAPZA2,0.06773234063115076,destabilizing
+EXOSC10,UBE2R2,0.08943273598607411,destabilizing
+EXOSC10,GTF2IRD1,0.07598166616897256,destabilizing
+EXOSC10,SBNO1,0.06051991172873712,destabilizing
+EXOSC10,BTBD9,0.07570062563614631,destabilizing
+EXOSC10,CNGB1,0.0931644525790277,destabilizing
+EXOSC10,ENSG00000228222,0.12139620084598582,destabilizing
+EXOSC10,RASA2,0.1010359667008679,destabilizing
+EXOSC10,WIPF2,0.10048128985362881,destabilizing
+EXOSC10,TSHZ2,0.05374163341793192,destabilizing
+EXOSC10,FRMD5,0.06659385734906226,destabilizing
+EXOSC10,LINC00174,0.08804323475236812,destabilizing
+EXOSC10,ARL3,0.07895958587061205,destabilizing
+EXOSC10,MBD5,0.058381389354770795,destabilizing
+EXOSC10,ELAVL3,0.08913666716909766,destabilizing
+EXOSC10,SLIT2,0.10969123156202688,destabilizing
+EXOSC10,UNC5C,0.07791732781047336,destabilizing
+EXOSC10,NEGR1,0.10214531283945359,destabilizing
+EXOSC10,ENOX1,0.12342277973917956,destabilizing
+EXOSC10,TOMM22,0.10923642571017701,destabilizing
+EXOSC10,LSAMP,0.0596971906247626,destabilizing
+EXOSC10,TMED2,0.06893588422308797,destabilizing
+EXOSC10,GRIK2,0.0883888462372239,destabilizing
+EXOSC10,LRRC37A3,0.11324766125031448,destabilizing
+EXOSC10,EYS,0.05684813491233301,destabilizing
+EXOSC10,ARID1B,0.06025522949187445,destabilizing
+EXOSC10,MLLT3,0.13149936316490043,destabilizing
+EXOSC10,ADGRB3,0.059088208505519234,destabilizing
+EXOSC10,SYPL1,0.06096205620523562,destabilizing
+EXOSC10,PTPRD,0.07484424661211352,destabilizing
+EXOSC10,LARP1B,0.07775229545821198,destabilizing
+CNOT1,MPHOSPH8,0.06777634788019038,destabilizing
+CNOT1,SYN3,0.06438756997868221,destabilizing
+CNOT6,CDK12,0.09123473763800914,destabilizing
+CNOT6,CENPP,0.11952562945491367,destabilizing
+CNOT6,ALK,0.11871647943158427,destabilizing
+CNOT6,MLLT3,0.0886811752917034,destabilizing
+CNOT7,TRERF1,0.09229437301512934,destabilizing
+CNOT7,SORCS1,0.07421813808004266,destabilizing
+CNOT7,PDE3A,0.09742082819456913,destabilizing
+CNOT7,UNC79,0.09868906361587686,destabilizing
+CNOT7,DOC2B,0.07518217684665617,destabilizing
+CNOT7,CHD1,0.05528133658261201,destabilizing
+CNOT7,MTMR7,0.11856157908650408,destabilizing
+CNOT7,EPB41L4B,0.06210665480544262,destabilizing
+CNOT7,LRRTM4,0.06729088271245182,destabilizing
+CNOT7,FRY,0.10303524882440653,destabilizing
+CNOT7,MACROD2,0.08947596785333782,destabilizing
+CNOT7,CDK12,0.11769320536653645,destabilizing
+CNOT7,MPHOSPH8,0.06742348327113,destabilizing
+CNOT7,UBR3,0.0670879822985364,destabilizing
+CNOT7,CHST12,0.11949062531973849,destabilizing
+CNOT7,EML5,0.09421101010130567,destabilizing
+CNOT7,PSME4,0.0893377482016656,destabilizing
+CNOT7,TMEM106B,0.09528260327007274,destabilizing
+CNOT7,KCNB2,0.09649822806016785,destabilizing
+CNOT7,ZNF521,0.08373649701275282,destabilizing
+CNOT7,GPR158,0.08485178974089308,destabilizing
+CNOT7,NCOA2,0.06857481888596662,destabilizing
+CNOT7,IFT172,0.07457029907067378,destabilizing
+CNOT7,SIK3,0.07938469960630348,destabilizing
+CNOT7,XKR6,0.07953219130947727,destabilizing
+CNOT7,TCF20,0.09745194042581742,destabilizing
+CNOT7,DGKI,0.06400853985870326,destabilizing
+CNOT7,EXOC6B,0.11751557293369061,destabilizing
+CNOT7,MAGI3,0.08168350552242061,destabilizing
+CNOT7,INPP4B,0.07896491288436014,destabilizing
+CNOT7,SPDYE3,0.07286098702690968,destabilizing
+CNOT7,DMD,0.13155721648088547,destabilizing
+CNOT7,MCU,0.07453359746161492,destabilizing
+CNOT7,SSH2,0.06300470578348352,destabilizing
+CNOT7,DOCK3,0.07693205666804465,destabilizing
+CNOT7,STAG1,0.07415435732101919,destabilizing
+CNOT7,UBE2R2,0.07367027400697367,destabilizing
+CNOT7,GTF2IRD1,0.06008699749650217,destabilizing
+CNOT7,FMN2,0.07346762136648986,destabilizing
+CNOT7,RASA2,0.07085987081372393,destabilizing
+CNOT7,FRMD4A,0.0671730355835868,destabilizing
+CNOT7,SEMA6D,0.06871897982281974,destabilizing
+CNOT7,KAZN,0.07449049360708737,destabilizing
+CNOT7,FRMD5,0.06886642569598479,destabilizing
+CNOT7,PPM1E,0.07179868636430509,destabilizing
+CNOT7,ELAVL3,0.0754469565671325,destabilizing
+CNOT7,CLASP1,0.07168722074901361,destabilizing
+CNOT7,UNC5C,0.09239005290157767,destabilizing
+CNOT7,NEGR1,0.0938238736342181,destabilizing
+CNOT7,NAV3,0.08825005995180463,destabilizing
+CNOT7,EBF1,0.06371448045304713,destabilizing
+CNOT7,TOMM22,0.08485441683738185,destabilizing
+CNOT7,AKAP6,0.07417772703451625,destabilizing
+CNOT7,ZBTB20,0.07586293808074879,destabilizing
+CNOT7,GRIK2,0.06137177621009099,destabilizing
+CNOT7,LRRC37A3,0.09617043887977571,destabilizing
+CNOT7,EYS,0.0640472436906127,destabilizing
+CNOT7,MLLT3,0.12053285758881735,destabilizing
+CNOT7,ADGRB3,0.05613202534578918,destabilizing
+CNOT7,ROBO1,0.07127859005476773,destabilizing
+CNOT7,PTPRD,0.08323858507783645,destabilizing
+CNOT7,LARP1B,0.09214866935896775,destabilizing
+PABPC1,TRERF1,0.3955680656122654,destabilizing
+PABPC1,SORCS1,0.29387140029952336,destabilizing
+PABPC1,NCOA1,0.1461473682398446,destabilizing
+PABPC1,COPA,0.19632644036610505,destabilizing
+PABPC1,FCHSD2,0.20353440028543918,destabilizing
+PABPC1,PDE3A,0.4565965006007183,destabilizing
+PABPC1,UNC79,0.4181174796768277,destabilizing
+PABPC1,DOC2B,0.2976365521215278,destabilizing
+PABPC1,TMTC2,0.3721998838600649,destabilizing
+PABPC1,KALRN,0.2886551352467136,destabilizing
+PABPC1,CHD1,0.23341219828443174,destabilizing
+PABPC1,PAK3,0.14615489954771826,destabilizing
+PABPC1,UBE2E2,0.17036353852580013,destabilizing
+PABPC1,PPARD,0.19974540396664198,destabilizing
+PABPC1,TOX,0.1221590910525368,destabilizing
+PABPC1,BRAF,0.12620943539811474,destabilizing
+PABPC1,RYR2,0.31063714222113037,destabilizing
+PABPC1,ZNF609,0.08374141399106236,destabilizing
+PABPC1,MTMR7,0.4053631847464219,destabilizing
+PABPC1,EIF4E,0.28245573488060666,destabilizing
+PABPC1,SOX11,0.15606218536386476,destabilizing
+PABPC1,EPB41L4B,0.31089338772418185,destabilizing
+PABPC1,CACNA1B,0.27825100031780703,destabilizing
+PABPC1,TBC1D5,0.17022971095497436,destabilizing
+PABPC1,LRRTM4,0.3112519460451876,destabilizing
+PABPC1,SIRPA,0.3449296809800614,destabilizing
+PABPC1,MAP4K3,0.10484002502188171,destabilizing
+PABPC1,PTEN,0.28601882229530445,destabilizing
+PABPC1,SPPL3,0.09278722946593476,destabilizing
+PABPC1,FRY,0.38210716169906744,destabilizing
+PABPC1,RUNX1T1,0.06216206422114991,destabilizing
+PABPC1,MACROD2,0.3496487592496082,destabilizing
+PABPC1,FOXN3,0.17152437417528904,destabilizing
+PABPC1,SHANK2,0.4255751336030692,destabilizing
+PABPC1,CDK12,0.4495914631228139,destabilizing
+PABPC1,RFX7,0.39596710872586416,destabilizing
+PABPC1,UBR5,0.23369618463416528,destabilizing
+PABPC1,JARID2,0.22458543633402062,destabilizing
+PABPC1,MPHOSPH8,0.277628338080065,destabilizing
+PABPC1,RGS7,-0.05526014648372726,stabilizing
+PABPC1,DIP2C,0.28695008341077854,destabilizing
+PABPC1,ZNF423,0.18416439048373545,destabilizing
+PABPC1,UBR3,0.281783579558139,destabilizing
+PABPC1,MGAT5,0.23287505154930604,destabilizing
+PABPC1,DLG2,0.27134792100413296,destabilizing
+PABPC1,CHST12,0.5531183652939841,destabilizing
+PABPC1,EML5,0.4241405757705863,destabilizing
+PABPC1,CENPP,0.19432852505623152,destabilizing
+PABPC1,PSME4,0.3730261034329627,destabilizing
+PABPC1,TMEM106B,0.4205865897907963,destabilizing
+PABPC1,RABGAP1L,0.08728787218749019,destabilizing
+PABPC1,EPHA5,0.3310773573484242,destabilizing
+PABPC1,KCNB2,0.3257737738636013,destabilizing
+PABPC1,ZNF83,0.2352931466583552,destabilizing
+PABPC1,SOX6,0.1877672014435156,destabilizing
+PABPC1,ZNF521,0.3326097340638021,destabilizing
+PABPC1,PLEKHA5,0.24365210395971829,destabilizing
+PABPC1,DTL,0.3264129923754314,destabilizing
+PABPC1,NOVA1,0.4080042961542567,destabilizing
+PABPC1,CCNY,0.3390143032608832,destabilizing
+PABPC1,ARIH1,0.2882075079750265,destabilizing
+PABPC1,FAM171B,0.12378650102705586,destabilizing
+PABPC1,EPB41L5,0.3001091358244028,destabilizing
+PABPC1,GPR158,0.401927364039665,destabilizing
+PABPC1,NCOA2,0.32475661624943986,destabilizing
+PABPC1,PRKCB,0.12460760785721921,destabilizing
+PABPC1,PUM2,0.09887765345844592,destabilizing
+PABPC1,ALK,0.19708027171116596,destabilizing
+PABPC1,ACACA,0.20650719871901566,destabilizing
+PABPC1,ARHGAP26,0.1284462276829377,destabilizing
+PABPC1,CTNND2,0.20740867063871832,destabilizing
+PABPC1,IFT172,0.352347741660851,destabilizing
+PABPC1,CCNT1,0.22454780949497452,destabilizing
+PABPC1,ENAH,0.10779817104900365,destabilizing
+PABPC1,DTWD2,0.3408652709061221,destabilizing
+PABPC1,SIK3,0.2255722356720304,destabilizing
+PABPC1,CPEB3,0.3821844223691017,destabilizing
+PABPC1,CADM2,0.1709113354385639,destabilizing
+PABPC1,XKR6,0.3950554081672132,destabilizing
+PABPC1,RMND5A,0.1601698023074305,destabilizing
+PABPC1,CADPS,0.207779201634395,destabilizing
+PABPC1,FGF13,0.13984625072344867,destabilizing
+PABPC1,TCF20,0.4265311602815965,destabilizing
+PABPC1,CDKAL1,0.18761588379738497,destabilizing
+PABPC1,DGKI,0.27690591848326185,destabilizing
+PABPC1,EXOC6B,0.43846187745778925,destabilizing
+PABPC1,MAGI3,0.33686024056473707,destabilizing
+PABPC1,SBF2,0.21857230426471647,destabilizing
+PABPC1,INPP4B,0.3777296758730141,destabilizing
+PABPC1,ERC1,0.20253812074607985,destabilizing
+PABPC1,PTPRS,0.39486148786428465,destabilizing
+PABPC1,CBFA2T2,0.238568471302721,destabilizing
+PABPC1,SPDYE3,0.33459831844739074,destabilizing
+PABPC1,TMEM178B,0.17881729068939156,destabilizing
+PABPC1,KMT2C,0.12822592016082152,destabilizing
+PABPC1,CACNA2D1,0.13706785691292614,destabilizing
+PABPC1,DMD,0.5257825372201612,destabilizing
+PABPC1,EIF4G3,0.11847510531212532,destabilizing
+PABPC1,MCU,0.334808868103425,destabilizing
+PABPC1,SSH2,0.29224589268138285,destabilizing
+PABPC1,TCF12,0.12250463957931372,destabilizing
+PABPC1,DOCK3,0.39566039668501396,destabilizing
+PABPC1,HS6ST3,0.42057542341696813,destabilizing
+PABPC1,LPP,0.47098576668402425,destabilizing
+PABPC1,STAG1,0.27499176471828596,destabilizing
+PABPC1,CAPZA2,0.3019166105700917,destabilizing
+PABPC1,ADGRL3,0.19804538083184528,destabilizing
+PABPC1,PHACTR1,0.13580750916845022,destabilizing
+PABPC1,UBE2R2,0.3490789000081234,destabilizing
+PABPC1,GTF2IRD1,0.33433767003991793,destabilizing
+PABPC1,CCBE1,0.25637366408743584,destabilizing
+PABPC1,FTX,0.14353163422184445,destabilizing
+PABPC1,VAPA,0.07823990163514062,destabilizing
+PABPC1,JMJD1C,0.09180919945827373,destabilizing
+PABPC1,TTC28,0.22734065101533396,destabilizing
+PABPC1,SBNO1,0.22024619519240368,destabilizing
+PABPC1,RIMS2,0.20574652458674741,destabilizing
+PABPC1,IGF1R,0.18428165152768888,destabilizing
+PABPC1,TRIO,0.23785468473838556,destabilizing
+PABPC1,KCND2,0.1570451350188814,destabilizing
+PABPC1,BTBD9,0.3792483034478888,destabilizing
+PABPC1,CNGB1,0.44953930485613414,destabilizing
+PABPC1,FMN2,0.3205132468092226,destabilizing
+PABPC1,ENSG00000228222,0.5134514503491509,destabilizing
+PABPC1,ATXN1,0.17232583465895307,destabilizing
+PABPC1,PRKN,0.507001909993565,destabilizing
+PABPC1,RASA2,0.3248188499466417,destabilizing
+PABPC1,PPP1R12B,0.3004905609747712,destabilizing
+PABPC1,FRMD4A,0.3079760243402472,destabilizing
+PABPC1,CAMK1D,0.17494791641343607,destabilizing
+PABPC1,PARD3,0.17436304221593715,destabilizing
+PABPC1,SEMA6D,0.30571816778148686,destabilizing
+PABPC1,WIPF2,0.3149656730529334,destabilizing
+PABPC1,WWOX,0.06870987829074231,destabilizing
+PABPC1,DLEU1,0.4926052105928666,destabilizing
+PABPC1,TSHZ2,0.19248595554444384,destabilizing
+PABPC1,MED13L,0.23172385118682093,destabilizing
+PABPC1,AFF3,0.12427259248109628,destabilizing
+PABPC1,KAZN,0.2936723943475201,destabilizing
+PABPC1,KANSL1,0.23082985602919254,destabilizing
+PABPC1,FRMD5,0.3001426077337771,destabilizing
+PABPC1,LINC00174,0.315136607491857,destabilizing
+PABPC1,PPM1E,0.32008820480078853,destabilizing
+PABPC1,ARL3,0.17636627696267937,destabilizing
+PABPC1,MBD5,0.27227938919108746,destabilizing
+PABPC1,ELAVL3,0.2928009911137569,destabilizing
+PABPC1,SLIT2,0.4750020046494498,destabilizing
+PABPC1,SLC8A1,0.14407401596909852,destabilizing
+PABPC1,CLASP1,0.22475660757397065,destabilizing
+PABPC1,DOCK4,0.1587479307495393,destabilizing
+PABPC1,UNC5C,0.3272580629443984,destabilizing
+PABPC1,CACNA2D3,-0.13886441709065594,stabilizing
+PABPC1,RC3H1,0.2577500292255208,destabilizing
+PABPC1,NEGR1,0.2872656573199521,destabilizing
+PABPC1,ENOX1,0.4955792309665591,destabilizing
+PABPC1,SCUBE1,0.2312718006825758,destabilizing
+PABPC1,GPHN,0.2995315878241422,destabilizing
+PABPC1,NAV3,0.39626797954867315,destabilizing
+PABPC1,EBF1,0.1470406097366357,destabilizing
+PABPC1,TOMM22,0.41596893581153405,destabilizing
+PABPC1,MBNL2,0.16648904732766068,destabilizing
+PABPC1,ANKFN1,0.11697136039900188,destabilizing
+PABPC1,MAGI2,0.19055336334489567,destabilizing
+PABPC1,LSAMP,0.23208757503287916,destabilizing
+PABPC1,AKAP6,0.3579195935563021,destabilizing
+PABPC1,TMED2,0.2468032177232924,destabilizing
+PABPC1,ZBTB20,0.3391847143033223,destabilizing
+PABPC1,GRIK2,0.32674959647203006,destabilizing
+PABPC1,MAML3,0.06986221003853467,destabilizing
+PABPC1,SOX5,0.24781826252549288,destabilizing
+PABPC1,LRRC37A3,0.42882160229668886,destabilizing
+PABPC1,TMEM132C,0.11328541198883772,destabilizing
+PABPC1,EYS,0.2645179788629474,destabilizing
+PABPC1,ARID1B,0.26015307902964396,destabilizing
+PABPC1,PRKCE,0.27272753245343606,destabilizing
+PABPC1,RBFOX1,-0.14263612624535355,stabilizing
+PABPC1,SDK1,0.2245364910490745,destabilizing
+PABPC1,NRG1,0.14978052434274053,destabilizing
+PABPC1,MLLT3,0.43634686214793394,destabilizing
+PABPC1,AUTS2,0.12538474201765976,destabilizing
+PABPC1,FMN1,0.19830279456793926,destabilizing
+PABPC1,ADGRB3,0.2411213298242933,destabilizing
+PABPC1,ROBO1,0.3675557627505698,destabilizing
+PABPC1,SYPL1,0.191198751253646,destabilizing
+PABPC1,PTPRD,0.28536167435754284,destabilizing
+PABPC1,FAM155A,0.3656263529321011,destabilizing
+PABPC1,LARP1B,0.4016699283423332,destabilizing
+MSI2,EML5,0.07792271824638337,destabilizing
+MSI2,TMEM106B,0.08448789189618114,destabilizing
+MSI2,DOCK3,0.07710905672905617,destabilizing
+AGO2,MACROD2,0.07383097729747137,destabilizing
+AGO2,AKAP6,0.0701198019958314,destabilizing
+DROSHA,CAPZA2,0.06926394100311582,destabilizing
+DROSHA,LRRC37A3,0.07656145897525118,destabilizing
+DROSHA,MLLT3,0.08218006590043028,destabilizing
+DICER1,TRERF1,0.09533972121719055,destabilizing
+DICER1,PDE3A,0.09776811681062099,destabilizing
+DICER1,DOC2B,0.062046309411872495,destabilizing
+DICER1,FRY,0.09043211489320609,destabilizing
+DICER1,MACROD2,0.07619727900841314,destabilizing
+DICER1,SHANK2,0.10394147106179111,destabilizing
+DICER1,CENPP,0.12951141676351466,destabilizing
+DICER1,TMEM106B,0.09148577616466323,destabilizing
+DICER1,KCNB2,0.09575576879572122,destabilizing
+DICER1,SOX6,0.06443734127839233,destabilizing
+DICER1,GPR158,0.09793553846109007,destabilizing
+DICER1,XKR6,0.08109456935385174,destabilizing
+DICER1,DMD,0.08982520582609309,destabilizing
+DICER1,MCU,0.06386812888825945,destabilizing
+DICER1,WIPF2,0.07320870195476283,destabilizing
+DICER1,FRMD5,0.06310484805676554,destabilizing
+DICER1,SLIT2,0.09160210944721406,destabilizing
+DICER1,UNC5C,0.07636302644816845,destabilizing
+DICER1,NEGR1,0.08907395374887535,destabilizing
+DICER1,GPHN,0.060703761182049384,destabilizing
+DICER1,GRIK2,0.060304237267544046,destabilizing
+DICER1,PRKCE,0.0678639419214086,destabilizing
+DICER1,MLLT3,0.08572083439439002,destabilizing
+ADAR,UNC79,0.09405778315889506,destabilizing
+ADAR,TMTC2,0.07658654465834071,destabilizing
+ADAR,RYR2,0.12315139064100437,destabilizing
+ADAR,LRRTM4,0.07329355878035,destabilizing
+ADAR,MACROD2,0.09035771908216914,destabilizing
+ADAR,SHANK2,0.1204830624077783,destabilizing
+ADAR,CDK12,0.09208322310879025,destabilizing
+ADAR,CHST12,0.11850456649843177,destabilizing
+ADAR,EML5,0.09644481900474572,destabilizing
+ADAR,CENPP,0.12284917227696683,destabilizing
+ADAR,PSME4,0.07041077623025084,destabilizing
+ADAR,ZNF521,0.07763215228234915,destabilizing
+ADAR,NCOA2,0.06435709363415029,destabilizing
+ADAR,CPEB3,0.1067283812034857,destabilizing
+ADAR,EXOC6B,0.08806180917242253,destabilizing
+ADAR,DMD,0.0893945487133388,destabilizing
+ADAR,MCU,0.07158979660034108,destabilizing
+ADAR,DOCK3,0.08150275092262299,destabilizing
+ADAR,HS6ST3,0.08711443891865318,destabilizing
+ADAR,LPP,0.09081741151188197,destabilizing
+ADAR,PRKN,0.0971037125961079,destabilizing
+ADAR,RASA2,0.06859990221925678,destabilizing
+ADAR,FRMD5,0.07302354588239465,destabilizing
+ADAR,LINC00174,0.062165073024674604,destabilizing
+ADAR,SLIT2,0.0926070311801646,destabilizing
+ADAR,UNC5C,0.06872924523492148,destabilizing
+ADAR,GPHN,0.06250681497982045,destabilizing
+ADAR,LRRC37A3,0.0832403380042452,destabilizing
+ADAR,MLLT3,0.09765332139006924,destabilizing
+ADARB1,EML5,0.07803984275201618,destabilizing
+CPSF1,CENPP,0.11939918159956894,destabilizing
+CPSF1,MAGI3,0.06909528408511137,destabilizing
+CPSF1,DMD,0.08031270503789628,destabilizing
+CPSF1,SYPL1,0.05328884877105955,destabilizing
+CPSF3,TRERF1,0.08677338109456922,destabilizing
+CPSF3,UNC79,0.09301502066668774,destabilizing
+CPSF3,KALRN,0.06854004428469905,destabilizing
+CPSF3,FRY,0.08322175365046633,destabilizing
+CPSF3,MPHOSPH8,0.07656508140372857,destabilizing
+CPSF3,KCNB2,0.09529605514715818,destabilizing
+CPSF3,PLEKHA5,0.06289674747663701,destabilizing
+CPSF3,NOVA1,0.13456980921501913,destabilizing
+CPSF3,ALK,0.10798195002584186,destabilizing
+CPSF3,DTWD2,0.13733345176540804,destabilizing
+CPSF3,XKR6,0.07393583403567962,destabilizing
+CPSF3,DGKI,0.06875507106367185,destabilizing
+CPSF3,EXOC6B,0.10098118969904267,destabilizing
+CPSF3,MAGI3,0.08143880455376426,destabilizing
+CPSF3,SSH2,0.06491134025284642,destabilizing
+CPSF3,STAG1,0.06554081267305677,destabilizing
+CPSF3,CAPZA2,0.08153887203311215,destabilizing
+CPSF3,ENSG00000228222,0.12401788039671145,destabilizing
+CPSF3,RASA2,0.07635473782411026,destabilizing
+CPSF3,SEMA6D,0.06655344530561118,destabilizing
+CPSF3,WIPF2,0.08271168869296062,destabilizing
+CPSF3,LINC00174,0.08435413594958821,destabilizing
+CPSF3,LRRC37A3,0.07578966646035216,destabilizing
+CPSF3,MLLT3,0.09475626351910157,destabilizing
+CSTF1,EIF4E,0.1392876845144812,destabilizing
+CSTF1,FRY,0.08690745149358914,destabilizing
+CSTF1,MACROD2,0.0689151124164659,destabilizing
+CSTF1,CDK12,0.09414321897782085,destabilizing
+CSTF1,ALK,0.1066687093747488,destabilizing
+CSTF1,CCNT1,0.06375121207175567,destabilizing
+CSTF1,XKR6,0.08524888484765018,destabilizing
+CSTF1,MAGI3,0.07523839841918101,destabilizing
+CSTF1,DMD,0.08540002486391117,destabilizing
+CSTF1,DOCK3,0.09959388982232636,destabilizing
+CSTF1,BTBD9,0.08000942282487589,destabilizing
+CSTF1,DLEU1,0.11075234451024324,destabilizing
+CSTF1,FRMD5,0.06252567496626901,destabilizing
+CSTF1,LINC00174,0.06298617328682833,destabilizing
+CSTF1,MBD5,0.06089093197896074,destabilizing
+CSTF1,AKAP6,0.06438185374044772,destabilizing
+CSTF1,ZBTB20,0.0792532203566666,destabilizing
+CSTF1,GRIK2,0.05897136427966865,destabilizing
+CSTF1,LRRC37A3,0.08067512286250098,destabilizing
+CSTF1,EYS,0.05498629241797912,destabilizing
+CSTF1,MLLT3,0.0836236798944941,destabilizing
+CSTF3,TRERF1,0.08970270257390375,destabilizing
+CSTF3,SORCS1,0.07206764819524628,destabilizing
+CSTF3,PDE3A,0.10613005069292555,destabilizing
+CSTF3,UNC79,0.08132843110204593,destabilizing
+CSTF3,DOC2B,0.07491237007774376,destabilizing
+CSTF3,TMTC2,0.11046401674538577,destabilizing
+CSTF3,KALRN,0.06082561915319397,destabilizing
+CSTF3,RYR2,0.10948349610185282,destabilizing
+CSTF3,MTMR7,0.14134318183439407,destabilizing
+CSTF3,EIF4E,0.12323707465145753,destabilizing
+CSTF3,LRRTM4,0.06964123171836413,destabilizing
+CSTF3,FRY,0.130891345499871,destabilizing
+CSTF3,MACROD2,0.09919251449325898,destabilizing
+CSTF3,SHANK2,0.11645232888120989,destabilizing
+CSTF3,CDK12,0.15205597223675194,destabilizing
+CSTF3,RFX7,0.11793428845910733,destabilizing
+CSTF3,MPHOSPH8,0.10852201887716648,destabilizing
+CSTF3,DLG2,0.0697528188964683,destabilizing
+CSTF3,CHST12,0.1534197247422882,destabilizing
+CSTF3,EML5,0.09806780807083369,destabilizing
+CSTF3,CENPP,0.18599637380469647,destabilizing
+CSTF3,PSME4,0.090126589976577,destabilizing
+CSTF3,TMEM106B,0.10599157586140145,destabilizing
+CSTF3,EPHA5,0.07624627215211534,destabilizing
+CSTF3,KCNB2,0.14791842989744816,destabilizing
+CSTF3,ZNF83,0.0734934861848259,destabilizing
+CSTF3,SOX6,0.06513879328658079,destabilizing
+CSTF3,ZNF521,0.10498437647432586,destabilizing
+CSTF3,NOVA1,0.12215000430317534,destabilizing
+CSTF3,CCNY,0.10691433380191086,destabilizing
+CSTF3,ARIH1,0.0788519985324413,destabilizing
+CSTF3,GPR158,0.10440862018239484,destabilizing
+CSTF3,ALK,0.17498227712970638,destabilizing
+CSTF3,IFT172,0.10860732604604466,destabilizing
+CSTF3,CCNT1,0.06904488202077412,destabilizing
+CSTF3,DTWD2,0.20029344229561633,destabilizing
+CSTF3,SIK3,0.09574558680007131,destabilizing
+CSTF3,CPEB3,0.10448141218540677,destabilizing
+CSTF3,XKR6,0.129585793797347,destabilizing
+CSTF3,DGKI,0.08552159277314199,destabilizing
+CSTF3,EXOC6B,0.13242407946681262,destabilizing
+CSTF3,MAGI3,0.1141977307827863,destabilizing
+CSTF3,SBF2,0.056048342821349566,destabilizing
+CSTF3,INPP4B,0.09305337322008025,destabilizing
+CSTF3,PTPRS,0.11928805252907847,destabilizing
+CSTF3,DMD,0.15532626298309132,destabilizing
+CSTF3,MCU,0.09325152979436224,destabilizing
+CSTF3,SSH2,0.0795391280450225,destabilizing
+CSTF3,DOCK3,0.1285558327863848,destabilizing
+CSTF3,HS6ST3,0.10259603605572079,destabilizing
+CSTF3,STAG1,0.06711144353254644,destabilizing
+CSTF3,CAPZA2,0.08598966764281073,destabilizing
+CSTF3,ADGRL3,0.0725774752915609,destabilizing
+CSTF3,PHACTR1,0.07611302059703265,destabilizing
+CSTF3,UBE2R2,0.08735536601898108,destabilizing
+CSTF3,GTF2IRD1,0.06381307158691896,destabilizing
+CSTF3,RIMS2,0.08035752177456103,destabilizing
+CSTF3,BTBD9,0.07861620014847859,destabilizing
+CSTF3,FMN2,0.06892766491571661,destabilizing
+CSTF3,ENSG00000228222,0.2071475420779967,destabilizing
+CSTF3,PRKN,0.13779689063968092,destabilizing
+CSTF3,RASA2,0.10143719916287641,destabilizing
+CSTF3,PPP1R12B,0.08264972914214275,destabilizing
+CSTF3,SEMA6D,0.06337630069247767,destabilizing
+CSTF3,WIPF2,0.09694700234144842,destabilizing
+CSTF3,DLEU1,0.11266235483628102,destabilizing
+CSTF3,KAZN,0.10741705966883214,destabilizing
+CSTF3,FRMD5,0.08139831278875943,destabilizing
+CSTF3,LINC00174,0.08998871468057885,destabilizing
+CSTF3,ARL3,0.07096665617737256,destabilizing
+CSTF3,ELAVL3,0.08116481646667331,destabilizing
+CSTF3,SLIT2,0.12931857404062,destabilizing
+CSTF3,CLASP1,0.0747118360739149,destabilizing
+CSTF3,UNC5C,0.09009452485024413,destabilizing
+CSTF3,NEGR1,0.11830500994675369,destabilizing
+CSTF3,ENOX1,0.1252694974459903,destabilizing
+CSTF3,GPHN,0.0760443790452211,destabilizing
+CSTF3,NAV3,0.10086460988771571,destabilizing
+CSTF3,TOMM22,0.09673791372539217,destabilizing
+CSTF3,AKAP6,0.08601959883788866,destabilizing
+CSTF3,ZBTB20,0.10649264362609,destabilizing
+CSTF3,GRIK2,0.06974164082578535,destabilizing
+CSTF3,LRRC37A3,0.11808763828253964,destabilizing
+CSTF3,EYS,0.06631531975944119,destabilizing
+CSTF3,MLLT3,0.15453739923111887,destabilizing
+CSTF3,ADGRB3,0.06223944612566768,destabilizing
+CSTF3,ROBO1,0.06747602894714834,destabilizing
+CSTF3,PTPRD,0.06304747506639108,destabilizing
+CSTF3,FAM155A,0.10801306610682215,destabilizing
+CSTF3,LARP1B,0.07964617596408093,destabilizing
+NUDT21,TRERF1,0.09604560011371044,destabilizing
+NUDT21,UNC79,0.08444036239060947,destabilizing
+NUDT21,DOC2B,0.07204467969210519,destabilizing
+NUDT21,TMTC2,0.1037290369141482,destabilizing
+NUDT21,KALRN,0.06356856573199128,destabilizing
+NUDT21,CHD1,0.05618828861368109,destabilizing
+NUDT21,RYR2,0.11215337782788162,destabilizing
+NUDT21,MTMR7,0.08289897872387038,destabilizing
+NUDT21,LRRTM4,0.06224627543875867,destabilizing
+NUDT21,PTEN,0.08600901938846618,destabilizing
+NUDT21,FRY,0.10803606765588553,destabilizing
+NUDT21,MACROD2,0.11161151170604104,destabilizing
+NUDT21,SHANK2,0.11762052496986217,destabilizing
+NUDT21,CDK12,0.13746536644552187,destabilizing
+NUDT21,MPHOSPH8,0.07572978922175036,destabilizing
+NUDT21,DLG2,0.08207639296118217,destabilizing
+NUDT21,CHST12,0.17624764974892446,destabilizing
+NUDT21,EML5,0.08965210638045278,destabilizing
+NUDT21,CENPP,0.12816123886701833,destabilizing
+NUDT21,TMEM106B,0.0722237241971343,destabilizing
+NUDT21,KCNB2,0.12000461561396276,destabilizing
+NUDT21,ZNF83,0.07815834045469239,destabilizing
+NUDT21,SOX6,0.05799733788872231,destabilizing
+NUDT21,PLEKHA5,0.06358900606860657,destabilizing
+NUDT21,CCNY,0.08811201299353086,destabilizing
+NUDT21,ARIH1,0.06446499889555524,destabilizing
+NUDT21,GPR158,0.09310480385234492,destabilizing
+NUDT21,ALK,0.15605988531621323,destabilizing
+NUDT21,IFT172,0.08753158562137882,destabilizing
+NUDT21,CCNT1,0.06664809982925428,destabilizing
+NUDT21,DTWD2,0.14027988984611794,destabilizing
+NUDT21,SIK3,0.07846826135078014,destabilizing
+NUDT21,XKR6,0.11560972818116534,destabilizing
+NUDT21,CADPS,0.07317172559815484,destabilizing
+NUDT21,TCF20,0.08681697643147533,destabilizing
+NUDT21,DGKI,0.06569645370024596,destabilizing
+NUDT21,EXOC6B,0.11291023011566637,destabilizing
+NUDT21,MAGI3,0.08391722768401133,destabilizing
+NUDT21,INPP4B,0.06887388073286974,destabilizing
+NUDT21,DMD,0.12442733984845361,destabilizing
+NUDT21,MCU,0.09087515680802546,destabilizing
+NUDT21,SSH2,0.07324601321007007,destabilizing
+NUDT21,DOCK3,0.1110166529128997,destabilizing
+NUDT21,CAPZA2,0.09210925603266339,destabilizing
+NUDT21,PHACTR1,0.06152546292766861,destabilizing
+NUDT21,UBE2R2,0.08035760484949908,destabilizing
+NUDT21,TTC28,0.08455708972778497,destabilizing
+NUDT21,FMN2,0.06306736907523405,destabilizing
+NUDT21,ENSG00000228222,0.12199087093362754,destabilizing
+NUDT21,RASA2,0.07802873031594024,destabilizing
+NUDT21,FRMD4A,0.054663060930955604,destabilizing
+NUDT21,SEMA6D,0.06896299575013663,destabilizing
+NUDT21,WIPF2,0.09319621516307972,destabilizing
+NUDT21,TSHZ2,0.06923003819292377,destabilizing
+NUDT21,KANSL1,0.06688057659098873,destabilizing
+NUDT21,FRMD5,0.08431306556841828,destabilizing
+NUDT21,MBD5,0.07952909639543311,destabilizing
+NUDT21,CLASP1,0.0808641738692469,destabilizing
+NUDT21,UNC5C,0.09604109755799453,destabilizing
+NUDT21,NAV3,0.07850366579556563,destabilizing
+NUDT21,TOMM22,0.0813279020093849,destabilizing
+NUDT21,AKAP6,0.08170739622027884,destabilizing
+NUDT21,ZBTB20,0.09588888787309495,destabilizing
+NUDT21,GRIK2,0.05996461693734474,destabilizing
+NUDT21,LRRC37A3,0.09146938641082333,destabilizing
+NUDT21,MLLT3,0.12252399581146103,destabilizing
+NUDT21,SYPL1,0.06167992311106333,destabilizing
+NUDT21,PTPRD,0.06751111308900302,destabilizing
+NUDT21,FAM155A,0.09844847369926357,destabilizing
+NUDT21,LARP1B,0.07289414794769329,destabilizing
+METTL3,SSH2,0.06513036841591055,destabilizing
+METTL3,CAPZA2,0.08458750005911704,destabilizing
+METTL3,GRIK2,0.05776824792958682,destabilizing
+METTL3,MLLT3,0.10018821371468753,destabilizing
+YTHDF1,PPARD,0.061897992386974895,destabilizing
+YTHDF1,EIF4E,0.13079819808966667,destabilizing
+YTHDF1,SHANK2,0.11490106424439782,destabilizing
+YTHDF1,CDK12,0.13646304890922292,destabilizing
+YTHDF1,CHST12,0.12289718421098637,destabilizing
+YTHDF1,CENPP,0.1178065532658791,destabilizing
+YTHDF1,PSME4,0.09805773503582678,destabilizing
+YTHDF1,NOVA1,0.10476755180145038,destabilizing
+YTHDF1,CPEB3,0.09506316822917107,destabilizing
+YTHDF1,XKR6,0.07129452949257604,destabilizing
+YTHDF1,MAGI3,0.07300178141570624,destabilizing
+YTHDF1,DMD,0.0973541620747929,destabilizing
+YTHDF1,MCU,0.07776774428207378,destabilizing
+YTHDF1,DOCK3,0.10928936735842795,destabilizing
+YTHDF1,GTF2IRD1,0.06054901868232777,destabilizing
+YTHDF1,CNGB1,0.08475013221300833,destabilizing
+YTHDF1,ENSG00000228222,0.12687148195133294,destabilizing
+YTHDF1,WIPF2,0.08082184386107691,destabilizing
+YTHDF1,KAZN,0.07046243394754333,destabilizing
+YTHDF1,SLIT2,0.09939540719399106,destabilizing
+YTHDF1,UNC5C,0.07742261947170086,destabilizing
+YTHDF1,ENOX1,0.11577947242134903,destabilizing
+YTHDF1,TOMM22,0.08488366755489243,destabilizing
+YTHDF1,AKAP6,0.0682190155318359,destabilizing
+YTHDF1,ZBTB20,0.07472381313704274,destabilizing
+YTHDF1,MLLT3,0.09762466623320186,destabilizing
+YTHDF1,ROBO1,0.06928390146057986,destabilizing
+YTHDF2,TRERF1,0.12586067751864882,destabilizing
+YTHDF2,SORCS1,0.10073515364228645,destabilizing
+YTHDF2,NCOA1,0.0596901727240283,destabilizing
+YTHDF2,COPA,0.06862565180162684,destabilizing
+YTHDF2,FCHSD2,0.09395363668953424,destabilizing
+YTHDF2,PDE3A,0.1594879890206339,destabilizing
+YTHDF2,UNC79,0.18862308933915908,destabilizing
+YTHDF2,DOC2B,0.1032240323520078,destabilizing
+YTHDF2,TMTC2,0.1557274428375522,destabilizing
+YTHDF2,KALRN,0.10123357362936684,destabilizing
+YTHDF2,CHD1,0.09589283562844989,destabilizing
+YTHDF2,PPARD,0.07880739043189677,destabilizing
+YTHDF2,MTMR7,0.14584935659877682,destabilizing
+YTHDF2,EIF4E,0.171893839233281,destabilizing
+YTHDF2,SOX11,0.08240379763043326,destabilizing
+YTHDF2,EPB41L4B,0.11611868938274848,destabilizing
+YTHDF2,CACNA1B,0.10288026788803922,destabilizing
+YTHDF2,LRRTM4,0.10852985446244481,destabilizing
+YTHDF2,SIRPA,0.14686762770628484,destabilizing
+YTHDF2,PTEN,0.09707845670746648,destabilizing
+YTHDF2,FRY,0.11739945366250362,destabilizing
+YTHDF2,MACROD2,0.13588030954490765,destabilizing
+YTHDF2,SHANK2,0.2061759751817783,destabilizing
+YTHDF2,CDK12,0.19674109377355764,destabilizing
+YTHDF2,RFX7,0.16352504360410874,destabilizing
+YTHDF2,UBR5,0.07662031397050738,destabilizing
+YTHDF2,JARID2,0.06942841720062704,destabilizing
+YTHDF2,MPHOSPH8,0.1232447040347016,destabilizing
+YTHDF2,DIP2C,0.1039456995385845,destabilizing
+YTHDF2,UBR3,0.07307022875187787,destabilizing
+YTHDF2,MGAT5,0.056206380499233446,destabilizing
+YTHDF2,DLG2,0.07885130774710739,destabilizing
+YTHDF2,CHST12,0.24144117050238362,destabilizing
+YTHDF2,EML5,0.18772644858211945,destabilizing
+YTHDF2,CENPP,0.11967394372591775,destabilizing
+YTHDF2,PSME4,0.15026752665928497,destabilizing
+YTHDF2,TMEM106B,0.1406834548798432,destabilizing
+YTHDF2,EPHA5,0.12661780495543126,destabilizing
+YTHDF2,KCNB2,0.12207599995389032,destabilizing
+YTHDF2,ZNF83,0.09058491003361811,destabilizing
+YTHDF2,SOX6,0.08827495833299319,destabilizing
+YTHDF2,ZNF521,0.14014326146178657,destabilizing
+YTHDF2,PLEKHA5,0.07374676603480458,destabilizing
+YTHDF2,DTL,0.12589738845343987,destabilizing
+YTHDF2,NOVA1,0.17242323062795198,destabilizing
+YTHDF2,CCNY,0.1482655720219708,destabilizing
+YTHDF2,ARIH1,0.10397452801792909,destabilizing
+YTHDF2,EPB41L5,0.0998445093662409,destabilizing
+YTHDF2,GPR158,0.12114568426991998,destabilizing
+YTHDF2,NCOA2,0.10165669019047208,destabilizing
+YTHDF2,MARCKS,0.06986169157008817,destabilizing
+YTHDF2,ALK,0.10939802686444533,destabilizing
+YTHDF2,ACACA,0.07222141603468951,destabilizing
+YTHDF2,IFT172,0.14562500605341694,destabilizing
+YTHDF2,CCNT1,0.07766248657818758,destabilizing
+YTHDF2,DTWD2,0.1820171061441085,destabilizing
+YTHDF2,SIK3,0.11233891489738312,destabilizing
+YTHDF2,CPEB3,0.1504990428709027,destabilizing
+YTHDF2,CADM2,0.08921394253180924,destabilizing
+YTHDF2,XKR6,0.1537289816517175,destabilizing
+YTHDF2,RMND5A,0.057860757049127555,destabilizing
+YTHDF2,CADPS,0.077370242925226,destabilizing
+YTHDF2,TCF20,0.13818622490511845,destabilizing
+YTHDF2,CDKAL1,0.08307854565839708,destabilizing
+YTHDF2,DGKI,0.09590412658186039,destabilizing
+YTHDF2,EXOC6B,0.1906074456856508,destabilizing
+YTHDF2,MAGI3,0.14812322742078113,destabilizing
+YTHDF2,SBF2,0.07743582643658455,destabilizing
+YTHDF2,INPP4B,0.13055698563867107,destabilizing
+YTHDF2,PTPRS,0.12814599225521633,destabilizing
+YTHDF2,CBFA2T2,0.059569589919934565,destabilizing
+YTHDF2,SPDYE3,0.12492046248751815,destabilizing
+YTHDF2,DMD,0.1800606793862356,destabilizing
+YTHDF2,EIF4G3,0.058939644970549834,destabilizing
+YTHDF2,MCU,0.10977562254848591,destabilizing
+YTHDF2,SSH2,0.10141926859899848,destabilizing
+YTHDF2,DOCK3,0.1598101527783526,destabilizing
+YTHDF2,HS6ST3,0.1463526308218389,destabilizing
+YTHDF2,LPP,0.19851767649801638,destabilizing
+YTHDF2,STAG1,0.12138392780831575,destabilizing
+YTHDF2,CAPZA2,0.12494003115721615,destabilizing
+YTHDF2,ADGRL3,0.07727742278354956,destabilizing
+YTHDF2,UBE2R2,0.16365761889350813,destabilizing
+YTHDF2,GTF2IRD1,0.09889768959039207,destabilizing
+YTHDF2,CCBE1,0.05573509943507484,destabilizing
+YTHDF2,FTX,0.07123466516325955,destabilizing
+YTHDF2,VAPA,0.05524297686719179,destabilizing
+YTHDF2,TTC28,0.08969630606662833,destabilizing
+YTHDF2,SBNO1,0.07647382100759402,destabilizing
+YTHDF2,RIMS2,0.07353984638159397,destabilizing
+YTHDF2,IGF1R,0.06373656035034167,destabilizing
+YTHDF2,TRIO,0.08295084132229705,destabilizing
+YTHDF2,BTBD9,0.1341703102743346,destabilizing
+YTHDF2,CNGB1,0.21269670795106863,destabilizing
+YTHDF2,FMN2,0.11783802631889632,destabilizing
+YTHDF2,ENSG00000228222,0.24064366135920015,destabilizing
+YTHDF2,ATXN1,0.06482645094010142,destabilizing
+YTHDF2,PRKN,0.16262189829601986,destabilizing
+YTHDF2,RASA2,0.1719810443340702,destabilizing
+YTHDF2,PPP1R12B,0.08469681786049005,destabilizing
+YTHDF2,FRMD4A,0.1031432547749087,destabilizing
+YTHDF2,CAMK1D,0.06128199363455393,destabilizing
+YTHDF2,SEMA6D,0.0986741191697419,destabilizing
+YTHDF2,WIPF2,0.15322476702295706,destabilizing
+YTHDF2,DLEU1,0.15971007464888215,destabilizing
+YTHDF2,TSHZ2,0.0720232526812145,destabilizing
+YTHDF2,MED13L,0.08284188206060239,destabilizing
+YTHDF2,AFF3,0.06226561219007716,destabilizing
+YTHDF2,KAZN,0.1163596286662109,destabilizing
+YTHDF2,KANSL1,0.0806488532259573,destabilizing
+YTHDF2,FRMD5,0.11465773294337925,destabilizing
+YTHDF2,LINC00174,0.16796910818721073,destabilizing
+YTHDF2,PPM1E,0.13732550644939528,destabilizing
+YTHDF2,ARL3,0.07290741232359255,destabilizing
+YTHDF2,MBD5,0.12134390793128816,destabilizing
+YTHDF2,ELAVL3,0.14044136153831804,destabilizing
+YTHDF2,SLIT2,0.19228871468548084,destabilizing
+YTHDF2,UNC5C,0.11798820598309813,destabilizing
+YTHDF2,CACNA2D3,-0.07589529528350124,stabilizing
+YTHDF2,RC3H1,0.10125338077083143,destabilizing
+YTHDF2,NEGR1,0.1312700570019238,destabilizing
+YTHDF2,ENOX1,0.2001126293906065,destabilizing
+YTHDF2,SCUBE1,0.09799182131117838,destabilizing
+YTHDF2,GPHN,0.10616805487455637,destabilizing
+YTHDF2,NAV3,0.1815544295642424,destabilizing
+YTHDF2,TOMM22,0.18753021666178313,destabilizing
+YTHDF2,MAGI2,0.08038330832478584,destabilizing
+YTHDF2,LSAMP,0.1265628830666357,destabilizing
+YTHDF2,AKAP6,0.10812242821895589,destabilizing
+YTHDF2,TMED2,0.11645144948273002,destabilizing
+YTHDF2,ZBTB20,0.10138781235480615,destabilizing
+YTHDF2,GRIK2,0.09908205862620138,destabilizing
+YTHDF2,SOX5,0.07360391660229101,destabilizing
+YTHDF2,LRRC37A3,0.1789582809577865,destabilizing
+YTHDF2,TMEM132C,0.0756045375992036,destabilizing
+YTHDF2,EYS,0.08863107436381384,destabilizing
+YTHDF2,ARID1B,0.08992943526210519,destabilizing
+YTHDF2,PRKCE,0.09832385908254257,destabilizing
+YTHDF2,RBFOX1,-0.0810240687594516,stabilizing
+YTHDF2,SDK1,0.07731654770712564,destabilizing
+YTHDF2,MLLT3,0.22646484227421013,destabilizing
+YTHDF2,ADGRB3,0.06422960627832991,destabilizing
+YTHDF2,ROBO1,0.10964517161820146,destabilizing
+YTHDF2,SYPL1,0.057547176469218385,destabilizing
+YTHDF2,PTPRD,0.10967647399245417,destabilizing
+YTHDF2,FAM155A,0.15428803023673773,destabilizing
+YTHDF2,LARP1B,0.14219809753166113,destabilizing
+YTHDF3,MACROD2,0.08283744023547455,destabilizing
+YTHDF3,ALK,0.10331336413139665,destabilizing
+YTHDF3,MLLT3,0.08533085608999112,destabilizing
+YTHDF3,PTPRD,0.056472000406473516,destabilizing
+YTHDF3,LARP1B,0.06174515782870721,destabilizing
+YTHDC1,TRERF1,0.14012589461274472,destabilizing
+YTHDC1,SORCS1,0.09009821449309373,destabilizing
+YTHDC1,FCHSD2,0.07570926852813305,destabilizing
+YTHDC1,PDE3A,0.1406147345401884,destabilizing
+YTHDC1,UNC79,0.13350515339068197,destabilizing
+YTHDC1,DOC2B,0.09900273403036434,destabilizing
+YTHDC1,TMTC2,0.11794504583319872,destabilizing
+YTHDC1,KALRN,0.06672009638382811,destabilizing
+YTHDC1,CHD1,0.07883656688277572,destabilizing
+YTHDC1,PPARD,0.08706886053052289,destabilizing
+YTHDC1,RYR2,0.12064455514614869,destabilizing
+YTHDC1,MTMR7,0.1101691855194088,destabilizing
+YTHDC1,EIF4E,0.1162534810677001,destabilizing
+YTHDC1,EPB41L4B,0.07584045611700073,destabilizing
+YTHDC1,CACNA1B,0.0665758666981746,destabilizing
+YTHDC1,LRRTM4,0.08462648866175791,destabilizing
+YTHDC1,SIRPA,0.11235574082348605,destabilizing
+YTHDC1,FRY,0.14102986434017298,destabilizing
+YTHDC1,MACROD2,0.10763820794301623,destabilizing
+YTHDC1,SHANK2,0.2048672181523087,destabilizing
+YTHDC1,CDK12,0.15349442278628256,destabilizing
+YTHDC1,RFX7,0.13666627184350838,destabilizing
+YTHDC1,UBR5,0.06255330044409049,destabilizing
+YTHDC1,MPHOSPH8,0.06711025692248118,destabilizing
+YTHDC1,DIP2C,0.08708581535554673,destabilizing
+YTHDC1,UBR3,0.09483097352562364,destabilizing
+YTHDC1,DLG2,0.07316673989721241,destabilizing
+YTHDC1,CHST12,0.18763799768372244,destabilizing
+YTHDC1,EML5,0.13092350155899415,destabilizing
+YTHDC1,CENPP,0.13507854265787347,destabilizing
+YTHDC1,PSME4,0.12184471805513893,destabilizing
+YTHDC1,TMEM106B,0.13336435636885083,destabilizing
+YTHDC1,EPHA5,0.08150511826302921,destabilizing
+YTHDC1,KCNB2,0.12361705348970868,destabilizing
+YTHDC1,ZNF83,0.08890874536374349,destabilizing
+YTHDC1,ZNF521,0.10722292801301053,destabilizing
+YTHDC1,DTL,0.09808602114397846,destabilizing
+YTHDC1,NOVA1,0.1336587228870345,destabilizing
+YTHDC1,CCNY,0.1166901927513516,destabilizing
+YTHDC1,ARIH1,0.09591642666176052,destabilizing
+YTHDC1,EPB41L5,0.057579446134010934,destabilizing
+YTHDC1,GPR158,0.12448808966289295,destabilizing
+YTHDC1,NCOA2,0.08425412700187813,destabilizing
+YTHDC1,ALK,0.1135218929862067,destabilizing
+YTHDC1,IFT172,0.07383386697561359,destabilizing
+YTHDC1,CCNT1,0.0943485132368288,destabilizing
+YTHDC1,DTWD2,0.15574417064605095,destabilizing
+YTHDC1,SIK3,0.12104413980309983,destabilizing
+YTHDC1,CPEB3,0.10635270528009289,destabilizing
+YTHDC1,CADM2,0.059105996007136515,destabilizing
+YTHDC1,XKR6,0.14062108173896137,destabilizing
+YTHDC1,CADPS,0.06251172157874187,destabilizing
+YTHDC1,TCF20,0.11459607182837667,destabilizing
+YTHDC1,CDKAL1,0.08102843668609688,destabilizing
+YTHDC1,DGKI,0.10484917450414034,destabilizing
+YTHDC1,EXOC6B,0.17079851408670826,destabilizing
+YTHDC1,MAGI3,0.11833533945223075,destabilizing
+YTHDC1,INPP4B,0.08925619058143089,destabilizing
+YTHDC1,PTPRS,0.16026670212508104,destabilizing
+YTHDC1,SPDYE3,0.0882892882273439,destabilizing
+YTHDC1,TMEM178B,0.06409251713364582,destabilizing
+YTHDC1,DMD,0.1603834329894565,destabilizing
+YTHDC1,MCU,0.1095789705416157,destabilizing
+YTHDC1,SSH2,0.07564105143119293,destabilizing
+YTHDC1,DOCK3,0.14075353100544713,destabilizing
+YTHDC1,HS6ST3,0.1302696453876212,destabilizing
+YTHDC1,LPP,0.11301818223260576,destabilizing
+YTHDC1,STAG1,0.09282127251806323,destabilizing
+YTHDC1,CAPZA2,0.09831267608120642,destabilizing
+YTHDC1,UBE2R2,0.12813210696439897,destabilizing
+YTHDC1,GTF2IRD1,0.08875129438440804,destabilizing
+YTHDC1,CCBE1,0.050814118749841694,destabilizing
+YTHDC1,SBNO1,0.0628219287298265,destabilizing
+YTHDC1,TRIO,0.05927183284068455,destabilizing
+YTHDC1,BTBD9,0.11852087657697788,destabilizing
+YTHDC1,CNGB1,0.12675776453502957,destabilizing
+YTHDC1,FMN2,0.08495932172714091,destabilizing
+YTHDC1,ENSG00000228222,0.1847560691149708,destabilizing
+YTHDC1,PRKN,0.17890165455829665,destabilizing
+YTHDC1,RASA2,0.09584515622048599,destabilizing
+YTHDC1,FRMD4A,0.07857435464848515,destabilizing
+YTHDC1,SEMA6D,0.06668676795758298,destabilizing
+YTHDC1,WIPF2,0.09330159080496261,destabilizing
+YTHDC1,DLEU1,0.13587463549419979,destabilizing
+YTHDC1,KAZN,0.10605986363386258,destabilizing
+YTHDC1,FRMD5,0.1004567760521346,destabilizing
+YTHDC1,LINC00174,0.0628672504858221,destabilizing
+YTHDC1,PPM1E,0.1074193378692963,destabilizing
+YTHDC1,ARL3,0.06986109067796606,destabilizing
+YTHDC1,MBD5,0.06814083141820178,destabilizing
+YTHDC1,ELAVL3,0.10768960814729597,destabilizing
+YTHDC1,SLIT2,0.1548137822520112,destabilizing
+YTHDC1,CLASP1,0.08641840773465267,destabilizing
+YTHDC1,UNC5C,0.10427251643835664,destabilizing
+YTHDC1,NEGR1,0.10039824322308909,destabilizing
+YTHDC1,ENOX1,0.14322876376000213,destabilizing
+YTHDC1,GPHN,0.09604756038692544,destabilizing
+YTHDC1,NAV3,0.1260155245770204,destabilizing
+YTHDC1,TOMM22,0.14970510313647728,destabilizing
+YTHDC1,MAGI2,0.05983696810810649,destabilizing
+YTHDC1,AKAP6,0.07916546845381663,destabilizing
+YTHDC1,ZBTB20,0.0942232247010183,destabilizing
+YTHDC1,GRIK2,0.08596930398791969,destabilizing
+YTHDC1,LRRC37A3,0.1561964711896076,destabilizing
+YTHDC1,EYS,0.06271210612854214,destabilizing
+YTHDC1,ARID1B,0.07088442164255646,destabilizing
+YTHDC1,PRKCE,0.06984461821827107,destabilizing
+YTHDC1,RBFOX1,-0.0737157768750954,stabilizing
+YTHDC1,MLLT3,0.16891756485017745,destabilizing
+YTHDC1,ADGRB3,0.05862757470785122,destabilizing
+YTHDC1,ROBO1,0.10541734054050218,destabilizing
+YTHDC1,PTPRD,0.08508605073247144,destabilizing
+YTHDC1,FAM155A,0.1478318014747646,destabilizing
+YTHDC1,LARP1B,0.12176946149682878,destabilizing
+ALKBH5,TRERF1,0.1439942711315705,destabilizing
+ALKBH5,SORCS1,0.09929649929518407,destabilizing
+ALKBH5,COPA,0.0695166283099589,destabilizing
+ALKBH5,FCHSD2,0.07363945580205503,destabilizing
+ALKBH5,PDE3A,0.16361702600133404,destabilizing
+ALKBH5,UNC79,0.1426408823979769,destabilizing
+ALKBH5,DOC2B,0.11966832062553202,destabilizing
+ALKBH5,TMTC2,0.14347121105425767,destabilizing
+ALKBH5,KALRN,0.10297702628585394,destabilizing
+ALKBH5,CHD1,0.08650254354891893,destabilizing
+ALKBH5,PPARD,0.07405425382990878,destabilizing
+ALKBH5,TOX,0.0782882146039525,destabilizing
+ALKBH5,RYR2,0.12237056234967826,destabilizing
+ALKBH5,MTMR7,0.1690512615696744,destabilizing
+ALKBH5,EIF4E,0.12579696234701163,destabilizing
+ALKBH5,SOX11,0.056064551486652854,destabilizing
+ALKBH5,EPB41L4B,0.11247247616933256,destabilizing
+ALKBH5,CACNA1B,0.10047465999578059,destabilizing
+ALKBH5,TBC1D5,0.06302614111979113,destabilizing
+ALKBH5,LRRTM4,0.11566469865987826,destabilizing
+ALKBH5,SIRPA,0.10599267149102427,destabilizing
+ALKBH5,PTEN,0.08439318243913776,destabilizing
+ALKBH5,FRY,0.14763404878581923,destabilizing
+ALKBH5,MACROD2,0.11884539298366839,destabilizing
+ALKBH5,SHANK2,0.20308726762573345,destabilizing
+ALKBH5,CDK12,0.1477688944307741,destabilizing
+ALKBH5,RFX7,0.13370440378615786,destabilizing
+ALKBH5,UBR5,0.0783917743796218,destabilizing
+ALKBH5,JARID2,0.08908784965861108,destabilizing
+ALKBH5,MPHOSPH8,0.10146481721376152,destabilizing
+ALKBH5,DIP2C,0.09804925215570438,destabilizing
+ALKBH5,UBR3,0.10914016318585495,destabilizing
+ALKBH5,MGAT5,0.06666125675886295,destabilizing
+ALKBH5,DLG2,0.08268468731721769,destabilizing
+ALKBH5,CHST12,0.20661599206015138,destabilizing
+ALKBH5,EML5,0.12215976214328565,destabilizing
+ALKBH5,PSME4,0.14267699173125048,destabilizing
+ALKBH5,TMEM106B,0.13387288589567398,destabilizing
+ALKBH5,RABGAP1L,0.0573247521716158,destabilizing
+ALKBH5,EPHA5,0.1099401783455351,destabilizing
+ALKBH5,KCNB2,0.11340795906182641,destabilizing
+ALKBH5,ZNF83,0.08825389704523572,destabilizing
+ALKBH5,SOX6,0.07399969170609028,destabilizing
+ALKBH5,ZNF521,0.13609351120259508,destabilizing
+ALKBH5,PLEKHA5,0.0633733313633708,destabilizing
+ALKBH5,NOVA1,0.1511146321268523,destabilizing
+ALKBH5,CCNY,0.13180080815460699,destabilizing
+ALKBH5,ARIH1,0.09659503867137746,destabilizing
+ALKBH5,EPB41L5,0.081880905093511,destabilizing
+ALKBH5,GPR158,0.12466359042855038,destabilizing
+ALKBH5,NCOA2,0.09624692612860743,destabilizing
+ALKBH5,ACACA,0.07024624192359966,destabilizing
+ALKBH5,CTNND2,0.08158451276781482,destabilizing
+ALKBH5,IFT172,0.12232727513897808,destabilizing
+ALKBH5,CCNT1,0.06652772787449135,destabilizing
+ALKBH5,SIK3,0.10219362201387998,destabilizing
+ALKBH5,CPEB3,0.13134550399199907,destabilizing
+ALKBH5,CADM2,0.07233112408161169,destabilizing
+ALKBH5,XKR6,0.15700602042652995,destabilizing
+ALKBH5,CADPS,0.07590539434722451,destabilizing
+ALKBH5,TCF20,0.15820395701245918,destabilizing
+ALKBH5,CDKAL1,0.0675754472081709,destabilizing
+ALKBH5,DGKI,0.109726954613462,destabilizing
+ALKBH5,EXOC6B,0.16085075376279592,destabilizing
+ALKBH5,MAGI3,0.12108044054423882,destabilizing
+ALKBH5,SBF2,0.0637449579670584,destabilizing
+ALKBH5,INPP4B,0.11878837807670924,destabilizing
+ALKBH5,PTPRS,0.12957582278387417,destabilizing
+ALKBH5,CBFA2T2,0.08297724325432972,destabilizing
+ALKBH5,SPDYE3,0.12640088726613158,destabilizing
+ALKBH5,DMD,0.19277281044286326,destabilizing
+ALKBH5,MCU,0.12440567841457982,destabilizing
+ALKBH5,SSH2,0.10165875382717024,destabilizing
+ALKBH5,DOCK3,0.14387741316703265,destabilizing
+ALKBH5,HS6ST3,0.10930507719643383,destabilizing
+ALKBH5,LPP,0.16737538962311027,destabilizing
+ALKBH5,STAG1,0.11368345017893876,destabilizing
+ALKBH5,CAPZA2,0.09117979130734241,destabilizing
+ALKBH5,ADGRL3,0.07360214761007156,destabilizing
+ALKBH5,UBE2R2,0.11627296912663047,destabilizing
+ALKBH5,GTF2IRD1,0.12017163748954456,destabilizing
+ALKBH5,CCBE1,0.060491296160725544,destabilizing
+ALKBH5,TTC28,0.0961376400915335,destabilizing
+ALKBH5,SBNO1,0.06562528153388396,destabilizing
+ALKBH5,RIMS2,0.06953495653683167,destabilizing
+ALKBH5,TRIO,0.07083055826787153,destabilizing
+ALKBH5,BTBD9,0.1487936690379777,destabilizing
+ALKBH5,CNGB1,0.14727863075182723,destabilizing
+ALKBH5,FMN2,0.12809353460593753,destabilizing
+ALKBH5,ENSG00000228222,0.17501660237485292,destabilizing
+ALKBH5,PRKN,0.14888383579375591,destabilizing
+ALKBH5,RASA2,0.12105546209050085,destabilizing
+ALKBH5,PPP1R12B,0.06875334902967704,destabilizing
+ALKBH5,FRMD4A,0.10327346491454502,destabilizing
+ALKBH5,SEMA6D,0.109293466199936,destabilizing
+ALKBH5,WIPF2,0.11066340155859206,destabilizing
+ALKBH5,DLEU1,0.17108219627623295,destabilizing
+ALKBH5,TSHZ2,0.07052828584176907,destabilizing
+ALKBH5,MED13L,0.07171145693371901,destabilizing
+ALKBH5,KAZN,0.12570479943084026,destabilizing
+ALKBH5,KANSL1,0.07582412176535358,destabilizing
+ALKBH5,FRMD5,0.10111110758196817,destabilizing
+ALKBH5,LINC00174,0.12483354423953266,destabilizing
+ALKBH5,PPM1E,0.1096454295290385,destabilizing
+ALKBH5,ARL3,0.08042996790235032,destabilizing
+ALKBH5,MBD5,0.0887593963397631,destabilizing
+ALKBH5,ELAVL3,0.12490949796324946,destabilizing
+ALKBH5,SLIT2,0.15577319811052662,destabilizing
+ALKBH5,CLASP1,0.0734253839156777,destabilizing
+ALKBH5,UNC5C,0.12692829642632344,destabilizing
+ALKBH5,CACNA2D3,-0.0549209043371544,stabilizing
+ALKBH5,RC3H1,0.09895366160303712,destabilizing
+ALKBH5,NEGR1,0.12449163040168314,destabilizing
+ALKBH5,ENOX1,0.15215554921003788,destabilizing
+ALKBH5,SCUBE1,0.0801326175498477,destabilizing
+ALKBH5,GPHN,0.09869335886555006,destabilizing
+ALKBH5,NAV3,0.1721109821297391,destabilizing
+ALKBH5,TOMM22,0.15554511694257311,destabilizing
+ALKBH5,MBNL2,0.060030947019183774,destabilizing
+ALKBH5,ANKFN1,0.07398002478286919,destabilizing
+ALKBH5,MAGI2,0.05716258274206831,destabilizing
+ALKBH5,LSAMP,0.07795960442482333,destabilizing
+ALKBH5,AKAP6,0.14256168420873414,destabilizing
+ALKBH5,ZBTB20,0.09145073110283893,destabilizing
+ALKBH5,GRIK2,0.11604409827296926,destabilizing
+ALKBH5,SOX5,0.07439212864620966,destabilizing
+ALKBH5,LRRC37A3,0.1858009498163019,destabilizing
+ALKBH5,EYS,0.07742901073286014,destabilizing
+ALKBH5,ARID1B,0.0843555272263007,destabilizing
+ALKBH5,PRKCE,0.08911773079553666,destabilizing
+ALKBH5,RBFOX1,-0.08559029193417589,stabilizing
+ALKBH5,SDK1,0.07362399745642861,destabilizing
+ALKBH5,NRG1,0.059001086382236306,destabilizing
+ALKBH5,MLLT3,0.16577428824592036,destabilizing
+ALKBH5,FMN1,0.07628203538833936,destabilizing
+ALKBH5,ADGRB3,0.07757173301378271,destabilizing
+ALKBH5,ROBO1,0.11991068853770541,destabilizing
+ALKBH5,SYPL1,0.06061952547810774,destabilizing
+ALKBH5,PTPRD,0.08600079514053217,destabilizing
+ALKBH5,FAM155A,0.12886776116141488,destabilizing
+ALKBH5,LARP1B,0.11078625285058169,destabilizing
+FTO,INPP4B,0.07575907268564279,destabilizing
+FTO,UNC5C,0.0767180720869161,destabilizing
+EWSR1,TRERF1,0.11927213703370179,destabilizing
+EWSR1,SORCS1,0.059182977848803366,destabilizing
+EWSR1,PDE3A,0.11218178169028714,destabilizing
+EWSR1,UNC79,0.1362827372410725,destabilizing
+EWSR1,DOC2B,0.11169393168768887,destabilizing
+EWSR1,TMTC2,0.13070821292969342,destabilizing
+EWSR1,KALRN,0.08926158769965782,destabilizing
+EWSR1,CHD1,0.06292943097178284,destabilizing
+EWSR1,MTMR7,0.13767580795200865,destabilizing
+EWSR1,EIF4E,0.15841366640718835,destabilizing
+EWSR1,SOX11,0.0705468701950052,destabilizing
+EWSR1,CACNA1B,0.08718613872700005,destabilizing
+EWSR1,PTEN,0.09027521435572156,destabilizing
+EWSR1,FRY,0.14388876069938747,destabilizing
+EWSR1,MACROD2,0.14800099490440816,destabilizing
+EWSR1,SHANK2,0.18069846933076544,destabilizing
+EWSR1,CDK12,0.1795881123084179,destabilizing
+EWSR1,RFX7,0.1115341637095978,destabilizing
+EWSR1,JARID2,0.05413173387123882,destabilizing
+EWSR1,MPHOSPH8,0.11456151158131268,destabilizing
+EWSR1,DIP2C,0.07223691305244788,destabilizing
+EWSR1,ZNF423,0.05742273314640674,destabilizing
+EWSR1,DLG2,0.07453744625260235,destabilizing
+EWSR1,CHST12,0.20498916918434945,destabilizing
+EWSR1,EML5,0.10976727055547188,destabilizing
+EWSR1,CENPP,0.23376938435900899,destabilizing
+EWSR1,PSME4,0.09204802438723171,destabilizing
+EWSR1,TMEM106B,0.12506026917814633,destabilizing
+EWSR1,EPHA5,0.08846775337678196,destabilizing
+EWSR1,KCNB2,0.14198108139261087,destabilizing
+EWSR1,ZNF83,0.10387483112876923,destabilizing
+EWSR1,SOX6,0.10008664374071383,destabilizing
+EWSR1,ZNF521,0.11715506098931311,destabilizing
+EWSR1,PLEKHA5,0.07135757214157737,destabilizing
+EWSR1,NOVA1,0.13018370464416876,destabilizing
+EWSR1,CCNY,0.1358453039684784,destabilizing
+EWSR1,ARIH1,0.0676793204538861,destabilizing
+EWSR1,EPB41L5,0.07889194451688444,destabilizing
+EWSR1,GPR158,0.09694285200847927,destabilizing
+EWSR1,NCOA2,0.067247702367218,destabilizing
+EWSR1,MARCKS,0.06173576342452825,destabilizing
+EWSR1,ALK,0.1907699548316171,destabilizing
+EWSR1,IFT172,0.1198548329205879,destabilizing
+EWSR1,CCNT1,0.07141514222002941,destabilizing
+EWSR1,DTWD2,0.19657000776262112,destabilizing
+EWSR1,SIK3,0.08750869308554703,destabilizing
+EWSR1,CPEB3,0.13493447799529873,destabilizing
+EWSR1,CADM2,0.07146435779183968,destabilizing
+EWSR1,XKR6,0.13701570872777108,destabilizing
+EWSR1,RMND5A,0.06317947118544036,destabilizing
+EWSR1,CDKAL1,0.07102132552997811,destabilizing
+EWSR1,DGKI,0.0876645379123992,destabilizing
+EWSR1,EXOC6B,0.11015267533098379,destabilizing
+EWSR1,MAGI3,0.13323311416746964,destabilizing
+EWSR1,SBF2,0.07510771958183333,destabilizing
+EWSR1,INPP4B,0.10385107230219609,destabilizing
+EWSR1,PTPRS,0.14980365656730155,destabilizing
+EWSR1,DMD,0.1487372222641595,destabilizing
+EWSR1,SSH2,0.0834705221900646,destabilizing
+EWSR1,DOCK3,0.1195458178787067,destabilizing
+EWSR1,HS6ST3,0.11289547117247099,destabilizing
+EWSR1,STAG1,0.07315904870862867,destabilizing
+EWSR1,CAPZA2,0.13774853137839604,destabilizing
+EWSR1,ADGRL3,0.05908324012018793,destabilizing
+EWSR1,PHACTR1,0.07841773693448698,destabilizing
+EWSR1,UBE2R2,0.09962141451034905,destabilizing
+EWSR1,GTF2IRD1,0.06424365184694321,destabilizing
+EWSR1,TTC28,0.10239899420095427,destabilizing
+EWSR1,SBNO1,0.06652657534775208,destabilizing
+EWSR1,RIMS2,0.057913539616331416,destabilizing
+EWSR1,BTBD9,0.08836499012922605,destabilizing
+EWSR1,CNGB1,0.11124969862296857,destabilizing
+EWSR1,FMN2,0.08222864595969315,destabilizing
+EWSR1,ENSG00000228222,0.2423112349883776,destabilizing
+EWSR1,SYN3,0.051290104172991444,destabilizing
+EWSR1,PRKN,0.09901158466089605,destabilizing
+EWSR1,RASA2,0.14727524112214074,destabilizing
+EWSR1,PPP1R12B,0.06658640315241066,destabilizing
+EWSR1,FRMD4A,0.07102977713975399,destabilizing
+EWSR1,SEMA6D,0.0841870856192957,destabilizing
+EWSR1,WIPF2,0.15495108143555542,destabilizing
+EWSR1,DLEU1,0.1317365713247514,destabilizing
+EWSR1,TSHZ2,0.06847586325976919,destabilizing
+EWSR1,KAZN,0.07217438601784537,destabilizing
+EWSR1,FRMD5,0.07618170260769612,destabilizing
+EWSR1,LINC00174,0.13801563560475597,destabilizing
+EWSR1,ARL3,0.1007696998199597,destabilizing
+EWSR1,MBD5,0.10687288161971654,destabilizing
+EWSR1,ELAVL3,0.11030411629669112,destabilizing
+EWSR1,SLIT2,0.1179813520868241,destabilizing
+EWSR1,CLASP1,0.07658105423382926,destabilizing
+EWSR1,UNC5C,0.1022148428690822,destabilizing
+EWSR1,NEGR1,0.1134860757531001,destabilizing
+EWSR1,ENOX1,0.1687310964893061,destabilizing
+EWSR1,GPHN,0.07556253812496924,destabilizing
+EWSR1,NAV3,0.0913195429524104,destabilizing
+EWSR1,EBF1,0.061561800102676464,destabilizing
+EWSR1,TOMM22,0.14895186419259143,destabilizing
+EWSR1,ANKFN1,0.07088529594502335,destabilizing
+EWSR1,LSAMP,0.07289992990855716,destabilizing
+EWSR1,AKAP6,0.09431150952885156,destabilizing
+EWSR1,TMED2,0.09694538485559016,destabilizing
+EWSR1,ZBTB20,0.11574887537776425,destabilizing
+EWSR1,GRIK2,0.09333716181816507,destabilizing
+EWSR1,LRRC37A3,0.16223862430615724,destabilizing
+EWSR1,EYS,0.07230371433791659,destabilizing
+EWSR1,RBFOX1,-0.0575645997541282,stabilizing
+EWSR1,MLLT3,0.22862996018064172,destabilizing
+EWSR1,ADGRB3,0.05732194678937074,destabilizing
+EWSR1,SYPL1,0.06488008821894854,destabilizing
+EWSR1,PTPRD,0.10755383811374493,destabilizing
+EWSR1,FAM155A,0.15545314116013098,destabilizing
+EWSR1,LARP1B,0.11473595311987136,destabilizing
+FUS,TRERF1,0.14567645235989124,destabilizing
+FUS,PDE3A,0.11091780137045515,destabilizing
+FUS,UNC79,0.11937045374176222,destabilizing
+FUS,DOC2B,0.08601351658345399,destabilizing
+FUS,TMTC2,0.13592172053529789,destabilizing
+FUS,KALRN,0.07740925214012756,destabilizing
+FUS,TOX,0.09311637339278357,destabilizing
+FUS,BRAF,0.054850597177234374,destabilizing
+FUS,RYR2,0.18765576281639912,destabilizing
+FUS,MTMR7,0.13758805202108335,destabilizing
+FUS,EIF4E,0.17191779682134417,destabilizing
+FUS,CACNA1B,0.07793758466041854,destabilizing
+FUS,WSB1,0.0693969397890274,destabilizing
+FUS,LRRTM4,0.07037321987160504,destabilizing
+FUS,PTEN,0.07673218376004902,destabilizing
+FUS,FRY,0.14638267102107771,destabilizing
+FUS,RUNX1T1,0.07171345614449258,destabilizing
+FUS,MACROD2,0.1228931461344649,destabilizing
+FUS,SHANK2,0.14531435661356965,destabilizing
+FUS,CDK12,0.20245055257079506,destabilizing
+FUS,RFX7,0.1062600278663329,destabilizing
+FUS,MPHOSPH8,0.11443304830420223,destabilizing
+FUS,CHST12,0.1580753246084275,destabilizing
+FUS,EML5,0.11888490790613664,destabilizing
+FUS,CENPP,0.3367793110162639,destabilizing
+FUS,PSME4,0.09526751331177476,destabilizing
+FUS,TMEM106B,0.09191554999600414,destabilizing
+FUS,EPHA5,0.0925253890604829,destabilizing
+FUS,KCNB2,0.19768811200425268,destabilizing
+FUS,ZNF83,0.09340706297283477,destabilizing
+FUS,SOX6,0.11545591208630067,destabilizing
+FUS,ZNF521,0.11008216049912173,destabilizing
+FUS,PLEKHA5,0.08381669269676552,destabilizing
+FUS,DTL,-0.1341680033843668,stabilizing
+FUS,NOVA1,0.17656703501102217,destabilizing
+FUS,CCNY,0.0924700915908366,destabilizing
+FUS,ARIH1,0.06928590018948952,destabilizing
+FUS,GPR158,0.11085227518707831,destabilizing
+FUS,ALK,0.2742469089097087,destabilizing
+FUS,IFT172,0.10966421357866074,destabilizing
+FUS,CCNT1,0.08448345689825779,destabilizing
+FUS,DTWD2,0.2727248229022015,destabilizing
+FUS,SIK3,0.0793795624271153,destabilizing
+FUS,CPEB3,0.14826024451132824,destabilizing
+FUS,XKR6,0.1307781409074188,destabilizing
+FUS,CADPS,0.07608775938669071,destabilizing
+FUS,FGF13,0.06416165449315013,destabilizing
+FUS,TCF20,0.08669480170950002,destabilizing
+FUS,CDKAL1,0.09257294507351684,destabilizing
+FUS,DGKI,0.102700448188646,destabilizing
+FUS,EXOC6B,0.10819541937258495,destabilizing
+FUS,MAGI3,0.12119258381904165,destabilizing
+FUS,INPP4B,0.08836630333543903,destabilizing
+FUS,TMEM178B,0.06866486177067398,destabilizing
+FUS,DMD,0.19092819960960342,destabilizing
+FUS,EIF4G3,0.059250051825787194,destabilizing
+FUS,MCU,0.10411812425590228,destabilizing
+FUS,SSH2,0.08622265747746727,destabilizing
+FUS,DOCK3,0.14066817834521694,destabilizing
+FUS,STAG1,0.07341147440942007,destabilizing
+FUS,CAPZA2,0.1122146021713085,destabilizing
+FUS,PHACTR1,0.10775380694288067,destabilizing
+FUS,UBE2R2,0.10600871729297333,destabilizing
+FUS,GTF2IRD1,0.05900338327943938,destabilizing
+FUS,JMJD1C,0.05416736254833271,destabilizing
+FUS,TTC28,0.0782969157360176,destabilizing
+FUS,RIMS2,0.08824852789198274,destabilizing
+FUS,BTBD9,0.10304516209381807,destabilizing
+FUS,CNGB1,0.0898849313043883,destabilizing
+FUS,FMN2,0.06979598401442905,destabilizing
+FUS,ENSG00000228222,0.1734090936623452,destabilizing
+FUS,SYN3,0.06488640380340802,destabilizing
+FUS,RASA2,0.14929961592118995,destabilizing
+FUS,PPP1R12B,0.06682415302216325,destabilizing
+FUS,FRMD4A,0.07837927951903345,destabilizing
+FUS,SEMA6D,0.1065605059418518,destabilizing
+FUS,WIPF2,0.13057070918992428,destabilizing
+FUS,DLEU1,0.1405441536786321,destabilizing
+FUS,TSHZ2,0.07263593568183249,destabilizing
+FUS,KAZN,0.07345472661477147,destabilizing
+FUS,KANSL1,0.07542573689455315,destabilizing
+FUS,FRMD5,0.08581081125271892,destabilizing
+FUS,LINC00174,0.11176037906791987,destabilizing
+FUS,ARL3,0.10729066874126728,destabilizing
+FUS,MBD5,0.07009183557817213,destabilizing
+FUS,ELAVL3,0.11683192569168191,destabilizing
+FUS,SLIT2,0.0848571775982836,destabilizing
+FUS,CLASP1,0.08991372719858762,destabilizing
+FUS,UNC5C,0.1208865860464222,destabilizing
+FUS,NEGR1,0.12795395576097007,destabilizing
+FUS,ENOX1,0.16791187325456447,destabilizing
+FUS,TOMM22,0.11492943979120349,destabilizing
+FUS,ANKFN1,0.07260826842402554,destabilizing
+FUS,AKAP6,0.10964770012597067,destabilizing
+FUS,TMED2,0.07948862176150152,destabilizing
+FUS,ZBTB20,0.12041978217858051,destabilizing
+FUS,GRIK2,0.0655337445564468,destabilizing
+FUS,SOX5,0.06614896124460581,destabilizing
+FUS,LRRC37A3,0.14315735764868048,destabilizing
+FUS,EYS,0.07510316027736218,destabilizing
+FUS,RORA,0.05231618971834701,destabilizing
+FUS,MLLT3,0.17716761305094145,destabilizing
+FUS,ROBO1,0.07473949631718178,destabilizing
+FUS,SYPL1,0.07546124529416508,destabilizing
+FUS,PTPRD,0.10680439475613045,destabilizing
+FUS,FAM155A,0.12757037540958788,destabilizing
+FUS,LARP1B,0.0702326343281684,destabilizing
+TAF15,TRERF1,0.08719204017304373,destabilizing
+TAF15,SORCS1,0.060842295141182695,destabilizing
+TAF15,UNC79,0.0895980695447562,destabilizing
+TAF15,MTMR7,0.0860257871976522,destabilizing
+TAF15,EIF4E,0.12306053528832504,destabilizing
+TAF15,FRY,0.08661122694142621,destabilizing
+TAF15,MACROD2,0.07491192501448433,destabilizing
+TAF15,CDK12,0.10823510412178294,destabilizing
+TAF15,MPHOSPH8,0.06529044185000518,destabilizing
+TAF15,CHST12,0.13814981488564604,destabilizing
+TAF15,EML5,0.10081588033235117,destabilizing
+TAF15,CENPP,0.14573820700914925,destabilizing
+TAF15,PSME4,0.06967519981339708,destabilizing
+TAF15,TMEM106B,0.07412545743412537,destabilizing
+TAF15,KCNB2,0.08867443540697213,destabilizing
+TAF15,ZNF83,0.07907495712626995,destabilizing
+TAF15,SOX6,0.07274934616374648,destabilizing
+TAF15,NOVA1,0.1036948754173273,destabilizing
+TAF15,CCNY,0.0809141826959328,destabilizing
+TAF15,ALK,0.10238366508463922,destabilizing
+TAF15,IFT172,0.07130836855636824,destabilizing
+TAF15,XKR6,0.0865147983464905,destabilizing
+TAF15,TCF20,0.10278777797728071,destabilizing
+TAF15,EXOC6B,0.10122889444112625,destabilizing
+TAF15,MAGI3,0.08197705273618087,destabilizing
+TAF15,DMD,0.09477049756389505,destabilizing
+TAF15,MCU,0.0737740948030454,destabilizing
+TAF15,SSH2,0.06378477645900016,destabilizing
+TAF15,DOCK3,0.09280959581756856,destabilizing
+TAF15,BTBD9,0.08329527563544291,destabilizing
+TAF15,ENSG00000228222,0.13387221608774125,destabilizing
+TAF15,PRKN,0.10074674797221196,destabilizing
+TAF15,WIPF2,0.09231586350154725,destabilizing
+TAF15,DLEU1,0.12652617641675598,destabilizing
+TAF15,FRMD5,0.06610813879322568,destabilizing
+TAF15,LINC00174,0.0674725975505757,destabilizing
+TAF15,SLIT2,0.11015494828405727,destabilizing
+TAF15,NEGR1,0.08018805588204773,destabilizing
+TAF15,TOMM22,0.07931626308042065,destabilizing
+TAF15,ZBTB20,0.08382962589555853,destabilizing
+TAF15,LRRC37A3,0.10239038065994975,destabilizing
+TAF15,EYS,0.05642809574493609,destabilizing
+TAF15,MLLT3,0.10335445614776294,destabilizing
+SFPQ,TRERF1,0.0873661274281534,destabilizing
+SFPQ,SORCS1,0.09438902046295261,destabilizing
+SFPQ,PDE3A,0.12081768605496063,destabilizing
+SFPQ,UNC79,0.11866848003811872,destabilizing
+SFPQ,DOC2B,0.07216258070840577,destabilizing
+SFPQ,TMTC2,0.10032210047091256,destabilizing
+SFPQ,KALRN,0.08272151361425016,destabilizing
+SFPQ,CHD1,0.0873708084769549,destabilizing
+SFPQ,PPARD,0.07718736710668771,destabilizing
+SFPQ,TOX,0.07838922213124914,destabilizing
+SFPQ,RYR2,0.1244190098739325,destabilizing
+SFPQ,MTMR7,0.0939227668132051,destabilizing
+SFPQ,EIF4E,0.10758646382245429,destabilizing
+SFPQ,LRRTM4,0.08757620038848209,destabilizing
+SFPQ,FRY,0.09541694683467897,destabilizing
+SFPQ,MACROD2,0.09195525633034397,destabilizing
+SFPQ,SHANK2,0.14274665311837406,destabilizing
+SFPQ,CDK12,0.1582493492569843,destabilizing
+SFPQ,RFX7,0.11342087120959579,destabilizing
+SFPQ,MPHOSPH8,0.0935464989206173,destabilizing
+SFPQ,DIP2C,0.07081402146770727,destabilizing
+SFPQ,DLG2,0.06471634156302779,destabilizing
+SFPQ,CHST12,0.12496702310385341,destabilizing
+SFPQ,EML5,0.1177878830362183,destabilizing
+SFPQ,CENPP,0.14336195300760418,destabilizing
+SFPQ,PSME4,0.11274498159186576,destabilizing
+SFPQ,TMEM106B,0.10345299211516289,destabilizing
+SFPQ,EPHA5,0.07283747803801041,destabilizing
+SFPQ,KCNB2,0.13686873215903791,destabilizing
+SFPQ,ZNF83,0.07662519204524719,destabilizing
+SFPQ,SOX6,0.0654118139766519,destabilizing
+SFPQ,ZNF521,0.07174120926235746,destabilizing
+SFPQ,PLEKHA5,0.05828016996560063,destabilizing
+SFPQ,NOVA1,0.12214108420965505,destabilizing
+SFPQ,CCNY,0.10242905715418056,destabilizing
+SFPQ,ARIH1,0.08512638034958164,destabilizing
+SFPQ,EPB41L5,0.07820039594886168,destabilizing
+SFPQ,GPR158,0.08389838003466064,destabilizing
+SFPQ,ALK,0.10792121582836012,destabilizing
+SFPQ,IFT172,0.08972513157547223,destabilizing
+SFPQ,CCNT1,0.06394860957833552,destabilizing
+SFPQ,SIK3,0.09467779911928383,destabilizing
+SFPQ,CPEB3,0.15413818203336052,destabilizing
+SFPQ,XKR6,0.11410433418685854,destabilizing
+SFPQ,CADPS,0.07379471785190689,destabilizing
+SFPQ,TCF20,0.10736550484349405,destabilizing
+SFPQ,CDKAL1,0.08776205718631283,destabilizing
+SFPQ,DGKI,0.09056883916060487,destabilizing
+SFPQ,EXOC6B,0.1385706070493731,destabilizing
+SFPQ,MAGI3,0.10451738218326889,destabilizing
+SFPQ,INPP4B,0.07743428687379073,destabilizing
+SFPQ,DMD,0.15616728485264844,destabilizing
+SFPQ,MCU,0.09709992522702048,destabilizing
+SFPQ,SSH2,0.07429581298442271,destabilizing
+SFPQ,DOCK3,0.12374150680235126,destabilizing
+SFPQ,HS6ST3,0.10268495442846003,destabilizing
+SFPQ,LPP,0.10182310026931547,destabilizing
+SFPQ,STAG1,0.07373198203827622,destabilizing
+SFPQ,CAPZA2,0.09350926062458151,destabilizing
+SFPQ,ADGRL3,0.059956970080108314,destabilizing
+SFPQ,PHACTR1,0.06046934444257739,destabilizing
+SFPQ,UBE2R2,0.08395993982659548,destabilizing
+SFPQ,GTF2IRD1,0.06839791139955563,destabilizing
+SFPQ,RIMS2,0.07399925945769718,destabilizing
+SFPQ,BTBD9,0.11135451881254475,destabilizing
+SFPQ,CNGB1,0.09500755311098114,destabilizing
+SFPQ,ENSG00000228222,0.15630727048190032,destabilizing
+SFPQ,PRKN,0.10408934710190786,destabilizing
+SFPQ,RASA2,0.0974217214287147,destabilizing
+SFPQ,FRMD4A,0.07146070620590834,destabilizing
+SFPQ,SEMA6D,0.07661471542107151,destabilizing
+SFPQ,WIPF2,0.09509806106259532,destabilizing
+SFPQ,TSHZ2,0.06847517843516573,destabilizing
+SFPQ,FRMD5,0.10539710671283042,destabilizing
+SFPQ,LINC00174,0.08234458415645192,destabilizing
+SFPQ,PPM1E,0.07304425106712555,destabilizing
+SFPQ,ARL3,0.09114633218647333,destabilizing
+SFPQ,ELAVL3,0.08498816519278239,destabilizing
+SFPQ,SLIT2,0.10117035619817043,destabilizing
+SFPQ,UNC5C,0.06538244680649521,destabilizing
+SFPQ,RC3H1,0.06594978629932007,destabilizing
+SFPQ,NEGR1,0.10676164381918403,destabilizing
+SFPQ,ENOX1,0.15021261935483762,destabilizing
+SFPQ,GPHN,0.06303096975270613,destabilizing
+SFPQ,NAV3,0.11292561014784327,destabilizing
+SFPQ,TOMM22,0.09677444347918102,destabilizing
+SFPQ,AKAP6,0.08916800666183913,destabilizing
+SFPQ,ZBTB20,0.09163284618365292,destabilizing
+SFPQ,GRIK2,0.06928734525650479,destabilizing
+SFPQ,LRRC37A3,0.11108615185281369,destabilizing
+SFPQ,RBFOX1,-0.053569050983175624,stabilizing
+SFPQ,MLLT3,0.1343386123710236,destabilizing
+SFPQ,SYPL1,0.05565571442173938,destabilizing
+SFPQ,PTPRD,0.07416437950542298,destabilizing
+SFPQ,FAM155A,0.11165177062887341,destabilizing
+SFPQ,LARP1B,0.07554789045161527,destabilizing
+NONO,TRERF1,0.2230283262927597,destabilizing
+NONO,SORCS1,0.146511102301934,destabilizing
+NONO,NCOA1,0.0669538617502621,destabilizing
+NONO,COPA,0.09151375072329064,destabilizing
+NONO,FCHSD2,0.09486850183766396,destabilizing
+NONO,PDE3A,0.20845159956233006,destabilizing
+NONO,UNC79,0.23983663477116288,destabilizing
+NONO,DOC2B,0.1423157895649359,destabilizing
+NONO,TMTC2,0.20077570728976973,destabilizing
+NONO,KALRN,0.15058064764825307,destabilizing
+NONO,CHD1,0.10908086182808985,destabilizing
+NONO,PAK3,0.058273869997357765,destabilizing
+NONO,UBE2E2,0.08466916330163614,destabilizing
+NONO,PPARD,0.09523731041294548,destabilizing
+NONO,TOX,0.09989612560832711,destabilizing
+NONO,BRAF,0.06938502194568778,destabilizing
+NONO,RYR2,0.18140821241505248,destabilizing
+NONO,MTMR7,0.23636367599486552,destabilizing
+NONO,EIF4E,0.21807870015524958,destabilizing
+NONO,EPB41L4B,0.1284364089028091,destabilizing
+NONO,CACNA1B,0.14263207194447644,destabilizing
+NONO,TBC1D5,0.06933078433248285,destabilizing
+NONO,LRRTM4,0.1334211747719983,destabilizing
+NONO,SIRPA,0.1576645673521898,destabilizing
+NONO,PTEN,0.15241697388111497,destabilizing
+NONO,FRY,0.23038365618515066,destabilizing
+NONO,MACROD2,0.17415060351789918,destabilizing
+NONO,SHANK2,0.2309080843669383,destabilizing
+NONO,CDK12,0.26849384060843207,destabilizing
+NONO,RFX7,0.1981005601786327,destabilizing
+NONO,UBR5,0.09719399983054212,destabilizing
+NONO,JARID2,0.12497891339758326,destabilizing
+NONO,MPHOSPH8,0.16465836606445503,destabilizing
+NONO,DIP2C,0.13494914261962476,destabilizing
+NONO,ZNF423,0.08440654704495952,destabilizing
+NONO,UBR3,0.12140392804010024,destabilizing
+NONO,MGAT5,0.07065479729207015,destabilizing
+NONO,DLG2,0.1575853551887165,destabilizing
+NONO,CHST12,0.2900462531842933,destabilizing
+NONO,EML5,0.20902018895618207,destabilizing
+NONO,CENPP,0.24865497044310209,destabilizing
+NONO,PSME4,0.17718860830226382,destabilizing
+NONO,TMEM106B,0.18279927714474126,destabilizing
+NONO,EPHA5,0.15655998368627708,destabilizing
+NONO,KCNB2,0.1993510085267888,destabilizing
+NONO,ZNF83,0.1318354184800264,destabilizing
+NONO,SOX6,0.12080992710131254,destabilizing
+NONO,ZNF521,0.17691782252940863,destabilizing
+NONO,PLEKHA5,0.13635609435100088,destabilizing
+NONO,NOVA1,0.2152278697967087,destabilizing
+NONO,CCNY,0.17486511151726186,destabilizing
+NONO,ARIH1,0.138847529937674,destabilizing
+NONO,FAM171B,0.052488260886518846,destabilizing
+NONO,EPB41L5,0.13019480539941297,destabilizing
+NONO,GPR158,0.2240294298406028,destabilizing
+NONO,NCOA2,0.14047546673427036,destabilizing
+NONO,ALK,0.2630408043234524,destabilizing
+NONO,ACACA,0.0913147397377731,destabilizing
+NONO,ARHGAP26,0.0658234265651014,destabilizing
+NONO,CTNND2,0.08977805486158673,destabilizing
+NONO,IFT172,0.17859966017042722,destabilizing
+NONO,CCNT1,0.12198911806357743,destabilizing
+NONO,DTWD2,0.29989829946502033,destabilizing
+NONO,SIK3,0.1381082112914465,destabilizing
+NONO,CPEB3,0.23660147554436708,destabilizing
+NONO,CADM2,0.07613238280037155,destabilizing
+NONO,XKR6,0.2118763273515341,destabilizing
+NONO,RMND5A,0.0716634075006975,destabilizing
+NONO,CADPS,0.120553292392804,destabilizing
+NONO,FGF13,0.09896963708791602,destabilizing
+NONO,TCF20,0.18689952956703826,destabilizing
+NONO,CDKAL1,0.13624780363639397,destabilizing
+NONO,DGKI,0.14834316668364358,destabilizing
+NONO,EXOC6B,0.2350989431639563,destabilizing
+NONO,MAGI3,0.18828360567223537,destabilizing
+NONO,SBF2,0.09472716708067908,destabilizing
+NONO,INPP4B,0.17772612776433852,destabilizing
+NONO,ERC1,0.08464072662458169,destabilizing
+NONO,PTPRS,0.22746793053422984,destabilizing
+NONO,CBFA2T2,0.07098653771595499,destabilizing
+NONO,SPDYE3,0.1320677288304693,destabilizing
+NONO,TMEM178B,0.08713107773675993,destabilizing
+NONO,CACNA2D1,0.06164474201096615,destabilizing
+NONO,DMD,0.2680202405254838,destabilizing
+NONO,EIF4G3,0.07267127542941094,destabilizing
+NONO,MCU,0.17946738889618122,destabilizing
+NONO,SSH2,0.15036209698842268,destabilizing
+NONO,DOCK3,0.21769853182887672,destabilizing
+NONO,HS6ST3,0.21161350432555787,destabilizing
+NONO,LPP,0.19896974698231376,destabilizing
+NONO,STAG1,0.15926715534728478,destabilizing
+NONO,CAPZA2,0.1942892378772318,destabilizing
+NONO,ADGRL3,0.09902356664313058,destabilizing
+NONO,PHACTR1,0.10408981059281594,destabilizing
+NONO,UBE2R2,0.18571212426013559,destabilizing
+NONO,GTF2IRD1,0.12595644450217258,destabilizing
+NONO,CCBE1,0.08838013264760537,destabilizing
+NONO,FTX,0.06695246872878724,destabilizing
+NONO,VAPA,0.07178007048561756,destabilizing
+NONO,TTC28,0.10765198325661657,destabilizing
+NONO,SBNO1,0.08894366623768338,destabilizing
+NONO,RIMS2,0.10950276280831109,destabilizing
+NONO,IGF1R,0.06726821314947395,destabilizing
+NONO,TRIO,0.06844989544845607,destabilizing
+NONO,KCND2,0.05964150622129083,destabilizing
+NONO,BTBD9,0.1966571557889868,destabilizing
+NONO,CNGB1,0.1976469700084653,destabilizing
+NONO,FMN2,0.13223951761085523,destabilizing
+NONO,ENSG00000228222,0.26965154589385737,destabilizing
+NONO,ATXN1,0.08072078859418795,destabilizing
+NONO,SYN3,0.06885551583110447,destabilizing
+NONO,PRKN,0.2165741457763318,destabilizing
+NONO,RASA2,0.18483749240477199,destabilizing
+NONO,PPP1R12B,0.1308008753288004,destabilizing
+NONO,FRMD4A,0.11615003234441747,destabilizing
+NONO,CAMK1D,0.07726976548938588,destabilizing
+NONO,SEMA6D,0.15344086101581064,destabilizing
+NONO,WIPF2,0.19393222741043892,destabilizing
+NONO,WWOX,0.05404690631168341,destabilizing
+NONO,DLEU1,0.27297427697091897,destabilizing
+NONO,TSHZ2,0.10175246188885731,destabilizing
+NONO,MED13L,0.11031362291989087,destabilizing
+NONO,AFF3,0.08625906804192736,destabilizing
+NONO,KAZN,0.1581497854116037,destabilizing
+NONO,KANSL1,0.09530950316933406,destabilizing
+NONO,FRMD5,0.1609247759356792,destabilizing
+NONO,LINC00174,0.1815309725745843,destabilizing
+NONO,PPM1E,0.14767116753045217,destabilizing
+NONO,ARL3,0.12095543024912428,destabilizing
+NONO,MBD5,0.14798672634311255,destabilizing
+NONO,ELAVL3,0.14521916197180043,destabilizing
+NONO,SLIT2,0.2183696022926277,destabilizing
+NONO,SLC8A1,0.07338407345596651,destabilizing
+NONO,CLASP1,0.12266289595112932,destabilizing
+NONO,UNC5C,0.17613180458400554,destabilizing
+NONO,CACNA2D3,-0.05988272301807545,stabilizing
+NONO,RC3H1,0.10192316505926055,destabilizing
+NONO,NEGR1,0.18060551643573294,destabilizing
+NONO,ENOX1,0.2709580650119047,destabilizing
+NONO,SCUBE1,0.10534660379416845,destabilizing
+NONO,GPHN,0.14394008767516855,destabilizing
+NONO,NAV3,0.1784352708775639,destabilizing
+NONO,TOMM22,0.229454179539932,destabilizing
+NONO,MBNL2,0.06939334670558431,destabilizing
+NONO,ANKFN1,0.07367299126838199,destabilizing
+NONO,MAGI2,0.08150648684088928,destabilizing
+NONO,LSAMP,0.11316330753033431,destabilizing
+NONO,AKAP6,0.1645668285621777,destabilizing
+NONO,TMED2,0.1429075636684417,destabilizing
+NONO,ZBTB20,0.19204966872574217,destabilizing
+NONO,GRIK2,0.17845521214224375,destabilizing
+NONO,SOX5,0.11232865832905427,destabilizing
+NONO,LRRC37A3,0.20586685582970116,destabilizing
+NONO,TMEM132C,0.05265210215661725,destabilizing
+NONO,EYS,0.13066415068323597,destabilizing
+NONO,ARID1B,0.10970697544247525,destabilizing
+NONO,PRKCE,0.10332993639761487,destabilizing
+NONO,RBFOX1,-0.07173592015004394,stabilizing
+NONO,SDK1,0.09081195529928793,destabilizing
+NONO,NRG1,0.07801749793187146,destabilizing
+NONO,RORA,0.06608522671376664,destabilizing
+NONO,MLLT3,0.24634379954021457,destabilizing
+NONO,FMN1,0.07923774649173636,destabilizing
+NONO,ADGRB3,0.10577911901667522,destabilizing
+NONO,ROBO1,0.17102512421694202,destabilizing
+NONO,SYPL1,0.10981629856712749,destabilizing
+NONO,PTPRD,0.1577770551280582,destabilizing
+NONO,FAM155A,0.2248867943518429,destabilizing
+NONO,LARP1B,0.18731485012994437,destabilizing
+NOVA1,NOVA1,-0.2626768539645661,stabilizing
+NOVA2,TRERF1,0.07710091377545492,destabilizing
+NOVA2,CHST12,0.12007496422036865,destabilizing
+SRRM4,SORCS1,0.05752313873196969,destabilizing
+SRRM4,MTMR7,0.0883190900945133,destabilizing
+SRRM4,EPB41L4B,0.06283942984068228,destabilizing
+SRRM4,SHANK2,0.11652174992893456,destabilizing
+SRRM4,CDK12,0.08642764368536703,destabilizing
+SRRM4,PSME4,0.08161734020137835,destabilizing
+SRRM4,EPB41L5,0.06369109585724551,destabilizing
+SRRM4,TCF20,0.0811077900946945,destabilizing
+SRRM4,EXOC6B,0.10118122340408879,destabilizing
+SRRM4,DMD,0.08109065845301591,destabilizing
+SRRM4,GTF2IRD1,0.06264396195145006,destabilizing
+SRRM4,NEGR1,0.08382337097516157,destabilizing
+SF3B1,TRERF1,0.09122576666908609,destabilizing
+SF3B1,UNC79,0.101040029402781,destabilizing
+SF3B1,DOC2B,0.060515579005428914,destabilizing
+SF3B1,TMTC2,0.08459962714770577,destabilizing
+SF3B1,LRRTM4,0.07625542185809442,destabilizing
+SF3B1,FRY,0.09749594161606347,destabilizing
+SF3B1,MACROD2,0.09135912707192341,destabilizing
+SF3B1,SHANK2,0.11182403977795262,destabilizing
+SF3B1,CDK12,0.11450000948335928,destabilizing
+SF3B1,DLG2,0.07726650950587327,destabilizing
+SF3B1,CHST12,0.14098852880207008,destabilizing
+SF3B1,EML5,0.08944635363557042,destabilizing
+SF3B1,TMEM106B,0.10166909390145175,destabilizing
+SF3B1,ZNF521,0.07368127713349826,destabilizing
+SF3B1,NOVA1,0.10675397218414628,destabilizing
+SF3B1,CCNY,0.1022060949541962,destabilizing
+SF3B1,ARIH1,0.06351816072130634,destabilizing
+SF3B1,NCOA2,0.06710841681524657,destabilizing
+SF3B1,CPEB3,0.10749140320705448,destabilizing
+SF3B1,XKR6,0.09959610699183057,destabilizing
+SF3B1,TCF20,0.08941088457010159,destabilizing
+SF3B1,EXOC6B,0.08839355729772218,destabilizing
+SF3B1,MAGI3,0.0869862113545946,destabilizing
+SF3B1,DMD,0.10055205107952908,destabilizing
+SF3B1,MCU,0.07325667257004034,destabilizing
+SF3B1,SSH2,0.07724815477744658,destabilizing
+SF3B1,DOCK3,0.07581842244481322,destabilizing
+SF3B1,HS6ST3,0.11174057883116818,destabilizing
+SF3B1,GTF2IRD1,0.07045447311782654,destabilizing
+SF3B1,FMN2,0.06623172425909518,destabilizing
+SF3B1,ENSG00000228222,0.12408327054475048,destabilizing
+SF3B1,PRKN,0.10545381776944387,destabilizing
+SF3B1,FRMD5,0.07245016913155869,destabilizing
+SF3B1,PPM1E,0.07327117768475361,destabilizing
+SF3B1,SLIT2,0.0986092252541244,destabilizing
+SF3B1,NEGR1,0.0759341242845733,destabilizing
+SF3B1,ENOX1,0.11076302074565175,destabilizing
+SF3B1,GPHN,0.05880829743062761,destabilizing
+SF3B1,NAV3,0.09552839922775985,destabilizing
+SF3B1,TOMM22,0.08037824757317998,destabilizing
+SF3B1,AKAP6,0.06639882474605809,destabilizing
+SF3B1,GRIK2,0.06981773200008301,destabilizing
+SF3B1,LRRC37A3,0.11068393517458999,destabilizing
+SF3B1,MLLT3,0.10799731496100869,destabilizing
+SF3B1,ROBO1,0.07362432543027718,destabilizing
+PRPF8,DOC2B,0.06570902292254747,destabilizing
+PRPF8,FRY,0.08604177192218421,destabilizing
+PRPF8,MACROD2,0.0646321614109586,destabilizing
+PRPF8,EML5,0.08681819723693136,destabilizing
+PRPF8,CENPP,0.20439599123997051,destabilizing
+PRPF8,KCNB2,0.11145328986727453,destabilizing
+PRPF8,DTL,-0.11571567898253325,stabilizing
+PRPF8,PUM2,-0.05285790472233099,stabilizing
+PRPF8,ALK,0.17901592985028997,destabilizing
+PRPF8,CCNT1,0.06372044674531048,destabilizing
+PRPF8,ENAH,-0.06609366780260238,stabilizing
+PRPF8,SIK3,0.08700119764554565,destabilizing
+PRPF8,MCU,0.07097092083072552,destabilizing
+PRPF8,TRIO,-0.062465333380717025,stabilizing
+PRPF8,ENSG00000228222,0.11540116823255833,destabilizing
+PRPF8,SYN3,0.051358714666599595,destabilizing
+PRPF8,RASA2,0.06711263953363913,destabilizing
+PRPF8,WIPF2,0.07378392197356777,destabilizing
+PRPF8,DOCK4,-0.06072081113173316,stabilizing
+PRPF8,KCNQ5,-0.05249171612588564,stabilizing
+PRPF8,MLLT3,0.09722360285912375,destabilizing
+PRPF8,AUTS2,-0.07253888352038833,stabilizing
+SNRNP200,TOX,0.06637811671636658,destabilizing
+SNRNP200,FRY,0.09222970740413282,destabilizing
+SNRNP200,RUNX1T1,0.06325237006794474,destabilizing
+SNRNP200,MACROD2,0.0701798832143161,destabilizing
+SNRNP200,CDK12,0.10696590527025744,destabilizing
+SNRNP200,DLG2,0.06634133950724294,destabilizing
+SNRNP200,CENPP,0.2090647570342755,destabilizing
+SNRNP200,KCNB2,0.10611253047499916,destabilizing
+SNRNP200,DTL,-0.09307223670690094,stabilizing
+SNRNP200,ALK,0.16079774048977222,destabilizing
+SNRNP200,XKR6,0.08694324267719454,destabilizing
+SNRNP200,DMD,0.07708237794405702,destabilizing
+SNRNP200,MCU,0.07005125670227683,destabilizing
+SNRNP200,PHACTR1,0.0656555111541415,destabilizing
+SNRNP200,ENSG00000228222,0.1430018242596071,destabilizing
+SNRNP200,SYN3,0.0510722725523965,destabilizing
+SNRNP200,WIPF2,0.07236908987785046,destabilizing
+SNRNP200,ANKFN1,0.07759653958662881,destabilizing
+SNRNP200,MLLT3,0.09182953247792341,destabilizing
+DDX3X,TMEM106B,0.07736799923383204,destabilizing
+DDX3X,DOCK3,0.08166980446945431,destabilizing
+DDX3X,UNC5C,0.0713110353532504,destabilizing
+DDX5,TRERF1,0.27307210339284865,destabilizing
+DDX5,SORCS1,0.17250816735312668,destabilizing
+DDX5,NCOA1,0.09298617398800227,destabilizing
+DDX5,COPA,0.12899182534750037,destabilizing
+DDX5,FCHSD2,0.15945173101139584,destabilizing
+DDX5,PDE3A,0.2718455191728201,destabilizing
+DDX5,UNC79,0.31210717277548017,destabilizing
+DDX5,DOC2B,0.19923375544835742,destabilizing
+DDX5,TMTC2,0.2816248260323178,destabilizing
+DDX5,KALRN,0.21982061710944292,destabilizing
+DDX5,CHD1,0.14173575995785911,destabilizing
+DDX5,PAK3,0.07753427414827423,destabilizing
+DDX5,UBE2E2,0.10082400120344967,destabilizing
+DDX5,PPARD,0.13312913049166528,destabilizing
+DDX5,TOX,0.06996438593413234,destabilizing
+DDX5,BRAF,0.08209139209718101,destabilizing
+DDX5,RYR2,0.2040242797226361,destabilizing
+DDX5,ZNF609,0.06749673863870845,destabilizing
+DDX5,MTMR7,0.28589752783829775,destabilizing
+DDX5,EIF4E,0.2839263382908393,destabilizing
+DDX5,SOX11,0.12659631576138541,destabilizing
+DDX5,EPB41L4B,0.20744933307261443,destabilizing
+DDX5,CACNA1B,0.20837418156846857,destabilizing
+DDX5,TBC1D5,0.12411665666809905,destabilizing
+DDX5,LRRTM4,0.21212211598054098,destabilizing
+DDX5,SIRPA,0.22406964126351747,destabilizing
+DDX5,PTEN,0.1769285656756917,destabilizing
+DDX5,FRY,0.2680013253547842,destabilizing
+DDX5,MACROD2,0.23849305747438873,destabilizing
+DDX5,FOXN3,0.0933466643309287,destabilizing
+DDX5,SHANK2,0.35973796273422964,destabilizing
+DDX5,CDK12,0.38822563829748996,destabilizing
+DDX5,BMPR1B,0.04992494036845782,destabilizing
+DDX5,RFX7,0.2698057507396226,destabilizing
+DDX5,UBR5,0.14094533457650427,destabilizing
+DDX5,JARID2,0.14212319266924595,destabilizing
+DDX5,MPHOSPH8,0.2360473403973155,destabilizing
+DDX5,DIP2C,0.21517066718052447,destabilizing
+DDX5,ZNF423,0.1253907854434453,destabilizing
+DDX5,UBR3,0.19963495461500425,destabilizing
+DDX5,MGAT5,0.13168709768341053,destabilizing
+DDX5,DLG2,0.17431751100610524,destabilizing
+DDX5,CHST12,0.4398011232711129,destabilizing
+DDX5,EML5,0.278971961334302,destabilizing
+DDX5,CENPP,0.2190463871795585,destabilizing
+DDX5,PSME4,0.2570254391175343,destabilizing
+DDX5,TMEM106B,0.29487069585629144,destabilizing
+DDX5,RABGAP1L,0.05852747439657196,destabilizing
+DDX5,EPHA5,0.22044996172667283,destabilizing
+DDX5,KCNB2,0.27470281648716843,destabilizing
+DDX5,ZNF83,0.20667903827969777,destabilizing
+DDX5,SOX6,0.1666927802273491,destabilizing
+DDX5,ZNF521,0.25144739384756154,destabilizing
+DDX5,PLEKHA5,0.1514978928319219,destabilizing
+DDX5,DTL,0.14352425348069475,destabilizing
+DDX5,NOVA1,0.32102875744153453,destabilizing
+DDX5,CCNY,0.26410535709119987,destabilizing
+DDX5,ARIH1,0.16663754000280032,destabilizing
+DDX5,FAM171B,0.08523249518883531,destabilizing
+DDX5,EPB41L5,0.22261679087011024,destabilizing
+DDX5,GPR158,0.22282663795612473,destabilizing
+DDX5,NCOA2,0.2035048469302737,destabilizing
+DDX5,PRKCB,0.08646133327149158,destabilizing
+DDX5,MARCKS,0.1120015476699468,destabilizing
+DDX5,ALK,0.2412035461498599,destabilizing
+DDX5,ACACA,0.14017864944796288,destabilizing
+DDX5,CTNND2,0.1169406631005538,destabilizing
+DDX5,IFT172,0.27491377834673947,destabilizing
+DDX5,CCNT1,0.16032628844721697,destabilizing
+DDX5,ENAH,0.08409972765056993,destabilizing
+DDX5,DTWD2,0.31830929943125397,destabilizing
+DDX5,SIK3,0.13230849728258404,destabilizing
+DDX5,CPEB3,0.264797030663222,destabilizing
+DDX5,CADM2,0.17139016981872796,destabilizing
+DDX5,XKR6,0.32381822866007076,destabilizing
+DDX5,RMND5A,0.12289215827581886,destabilizing
+DDX5,CADPS,0.12130555640293811,destabilizing
+DDX5,FGF13,0.08029785346034278,destabilizing
+DDX5,TCF20,0.24923084138561785,destabilizing
+DDX5,CDKAL1,0.13523122303917162,destabilizing
+DDX5,DGKI,0.18141396485905636,destabilizing
+DDX5,EXOC6B,0.2877875729050628,destabilizing
+DDX5,MAGI3,0.26297305140448346,destabilizing
+DDX5,SBF2,0.157333318640182,destabilizing
+DDX5,INPP4B,0.2587862069935939,destabilizing
+DDX5,ERC1,0.11617686684648873,destabilizing
+DDX5,PTPRS,0.30808969524785834,destabilizing
+DDX5,CBFA2T2,0.14953509666459935,destabilizing
+DDX5,SPDYE3,0.2478575750348737,destabilizing
+DDX5,TMEM178B,0.12497516570261241,destabilizing
+DDX5,KMT2C,0.09667847157121472,destabilizing
+DDX5,CACNA2D1,0.059092762527177295,destabilizing
+DDX5,DMD,0.3742747672380122,destabilizing
+DDX5,EIF4G3,0.08196722452851474,destabilizing
+DDX5,MCU,0.1547006046410554,destabilizing
+DDX5,SSH2,0.2035448128789825,destabilizing
+DDX5,TCF12,0.05112845526166225,destabilizing
+DDX5,DOCK3,0.30650191292703727,destabilizing
+DDX5,HS6ST3,0.2613114462662903,destabilizing
+DDX5,LPP,0.29802987803558456,destabilizing
+DDX5,STAG1,0.20787299670752193,destabilizing
+DDX5,CAPZA2,0.243929964246517,destabilizing
+DDX5,ADGRL3,0.1304202944881161,destabilizing
+DDX5,PHACTR1,0.09788879979990453,destabilizing
+DDX5,UBE2R2,0.2846462324594982,destabilizing
+DDX5,GTF2IRD1,0.23484854728632995,destabilizing
+DDX5,CCBE1,0.14366192993117377,destabilizing
+DDX5,FTX,0.1138550310201881,destabilizing
+DDX5,JMJD1C,0.08778167825703695,destabilizing
+DDX5,TTC28,0.17876023351661796,destabilizing
+DDX5,SBNO1,0.17007643967462,destabilizing
+DDX5,RIMS2,0.15774934444360783,destabilizing
+DDX5,IGF1R,0.1180567579913155,destabilizing
+DDX5,TRIO,0.13563796210107337,destabilizing
+DDX5,KCND2,0.07214409406982888,destabilizing
+DDX5,BTBD9,0.26557041631220785,destabilizing
+DDX5,CNGB1,0.3066086415355457,destabilizing
+DDX5,FMN2,0.22487382721337848,destabilizing
+DDX5,ENSG00000228222,0.38652233263962454,destabilizing
+DDX5,ATXN1,0.07856746563043412,destabilizing
+DDX5,PRKN,0.33197976553090236,destabilizing
+DDX5,RASA2,0.29656141327617763,destabilizing
+DDX5,PPP1R12B,0.14806114603941808,destabilizing
+DDX5,FRMD4A,0.2059231331731325,destabilizing
+DDX5,CAMK1D,0.09023938364943528,destabilizing
+DDX5,PARD3,0.0916109757125991,destabilizing
+DDX5,SEMA6D,0.21658792244391073,destabilizing
+DDX5,WIPF2,0.2937887406988392,destabilizing
+DDX5,DLEU1,0.30745435674146737,destabilizing
+DDX5,TSHZ2,0.14428110392543997,destabilizing
+DDX5,MED13L,0.16374407109858907,destabilizing
+DDX5,AFF3,0.09438139764378176,destabilizing
+DDX5,KAZN,0.22824674487855257,destabilizing
+DDX5,KANSL1,0.15042597622464454,destabilizing
+DDX5,FRMD5,0.21459959643816431,destabilizing
+DDX5,LINC00174,0.2778819929640136,destabilizing
+DDX5,PPM1E,0.21772889944142987,destabilizing
+DDX5,ARL3,0.1644500888589351,destabilizing
+DDX5,MBD5,0.1945273401832655,destabilizing
+DDX5,ELAVL3,0.2640374552298544,destabilizing
+DDX5,SLIT2,0.32973605587018595,destabilizing
+DDX5,SLC8A1,0.05435532611423526,destabilizing
+DDX5,CLASP1,0.17597858916649814,destabilizing
+DDX5,DOCK4,0.06440872946139961,destabilizing
+DDX5,UNC5C,0.22692316947587005,destabilizing
+DDX5,CACNA2D3,-0.13081774227776952,stabilizing
+DDX5,RC3H1,0.1754676169003483,destabilizing
+DDX5,NEGR1,0.2510492915015511,destabilizing
+DDX5,ENOX1,0.3437084056315184,destabilizing
+DDX5,SCUBE1,0.1964587779051395,destabilizing
+DDX5,GPHN,0.16902756116737247,destabilizing
+DDX5,NAV3,0.27872853756114746,destabilizing
+DDX5,EBF1,0.1120007265067494,destabilizing
+DDX5,TOMM22,0.32225322494309094,destabilizing
+DDX5,ANKFN1,0.07298390559361051,destabilizing
+DDX5,MAGI2,0.14367952641352966,destabilizing
+DDX5,LSAMP,0.19092867733230276,destabilizing
+DDX5,AKAP6,0.22397194472776655,destabilizing
+DDX5,TMED2,0.22483577293108742,destabilizing
+DDX5,ZBTB20,0.2061725394268296,destabilizing
+DDX5,GRIK2,0.24577727304793767,destabilizing
+DDX5,SOX5,0.18679421174006697,destabilizing
+DDX5,LRRC37A3,0.3803354798571381,destabilizing
+DDX5,TMEM132C,0.1234474244078461,destabilizing
+DDX5,EYS,0.21731217061483687,destabilizing
+DDX5,ARID1B,0.17608511812896577,destabilizing
+DDX5,PRKCE,0.20256629744378077,destabilizing
+DDX5,RBFOX1,-0.17557933393274616,stabilizing
+DDX5,SDK1,0.15488943455164528,destabilizing
+DDX5,NRG1,0.09693093234992489,destabilizing
+DDX5,MLLT3,0.3912535512736006,destabilizing
+DDX5,AUTS2,0.05793002509954359,destabilizing
+DDX5,FMN1,0.12222533333197573,destabilizing
+DDX5,ADGRB3,0.1489719584511745,destabilizing
+DDX5,ROBO1,0.23433724737954525,destabilizing
+DDX5,SYPL1,0.14226196136782823,destabilizing
+DDX5,PTPRD,0.222634257403466,destabilizing
+DDX5,FAM155A,0.2521126470833999,destabilizing
+DDX5,LARP1B,0.2569534881645491,destabilizing
+DDX6,TRERF1,0.10961212305207584,destabilizing
+DDX6,SORCS1,0.0760693699385343,destabilizing
+DDX6,PDE3A,0.12050185129416244,destabilizing
+DDX6,UNC79,0.10230557457139607,destabilizing
+DDX6,DOC2B,0.09950873605587714,destabilizing
+DDX6,TMTC2,0.09478524667202759,destabilizing
+DDX6,KALRN,0.10457928810820014,destabilizing
+DDX6,MTMR7,0.10159503070896385,destabilizing
+DDX6,EIF4E,0.11360921594282586,destabilizing
+DDX6,EPB41L4B,0.07533729336123089,destabilizing
+DDX6,CACNA1B,0.09329024367730383,destabilizing
+DDX6,LRRTM4,0.09556451004896184,destabilizing
+DDX6,FRY,0.10751467838582367,destabilizing
+DDX6,MACROD2,0.09956959366361845,destabilizing
+DDX6,SHANK2,0.15831791882713064,destabilizing
+DDX6,CDK12,0.14500456331704506,destabilizing
+DDX6,MPHOSPH8,0.07680144468006699,destabilizing
+DDX6,DLG2,0.07520473696921783,destabilizing
+DDX6,CHST12,0.21450591826415707,destabilizing
+DDX6,EML5,0.1061462525826546,destabilizing
+DDX6,CENPP,0.12798815416474635,destabilizing
+DDX6,PSME4,0.07735628396545864,destabilizing
+DDX6,TMEM106B,0.07419634901702021,destabilizing
+DDX6,EPHA5,0.08184597689210465,destabilizing
+DDX6,ZNF83,0.07915828977845445,destabilizing
+DDX6,SOX6,0.056760328714783176,destabilizing
+DDX6,PLEKHA5,0.06660746004180071,destabilizing
+DDX6,NOVA1,0.10095220708309081,destabilizing
+DDX6,CCNY,0.09966775891643019,destabilizing
+DDX6,ARIH1,0.0679706240392942,destabilizing
+DDX6,EPB41L5,0.06741149942667353,destabilizing
+DDX6,GPR158,0.08397852082805136,destabilizing
+DDX6,NCOA2,0.08471887999736341,destabilizing
+DDX6,ALK,0.10345276998142873,destabilizing
+DDX6,IFT172,0.08800691907954251,destabilizing
+DDX6,CCNT1,0.05463003430232756,destabilizing
+DDX6,SIK3,0.07777286203712841,destabilizing
+DDX6,CADM2,0.06327273802859025,destabilizing
+DDX6,XKR6,0.12294470725465792,destabilizing
+DDX6,EXOC6B,0.11605070388703818,destabilizing
+DDX6,MAGI3,0.07421782658635681,destabilizing
+DDX6,SBF2,0.0689848517841201,destabilizing
+DDX6,INPP4B,0.09411483546137384,destabilizing
+DDX6,SPDYE3,0.07664129933513601,destabilizing
+DDX6,DMD,0.15196679098408386,destabilizing
+DDX6,MCU,0.07447807964676492,destabilizing
+DDX6,SSH2,0.06961768359134184,destabilizing
+DDX6,DOCK3,0.1403082414412366,destabilizing
+DDX6,HS6ST3,0.12928011961740157,destabilizing
+DDX6,LPP,0.09616941637666356,destabilizing
+DDX6,STAG1,0.06831444651079822,destabilizing
+DDX6,CAPZA2,0.08035821652891967,destabilizing
+DDX6,ADGRL3,0.06119420223710417,destabilizing
+DDX6,UBE2R2,0.09832848453393137,destabilizing
+DDX6,GTF2IRD1,0.0857428238849828,destabilizing
+DDX6,SBNO1,0.07308058108480465,destabilizing
+DDX6,BTBD9,0.08564014240077598,destabilizing
+DDX6,CNGB1,0.09866608229654054,destabilizing
+DDX6,FMN2,0.08106032812343908,destabilizing
+DDX6,ENSG00000228222,0.15660562357808874,destabilizing
+DDX6,PRKN,0.1549563870741409,destabilizing
+DDX6,RASA2,0.09873072440819645,destabilizing
+DDX6,FRMD4A,0.08154878660105881,destabilizing
+DDX6,SEMA6D,0.06166600756056368,destabilizing
+DDX6,WIPF2,0.09389998631005289,destabilizing
+DDX6,KAZN,0.07982404046213346,destabilizing
+DDX6,FRMD5,0.0842687512497959,destabilizing
+DDX6,LINC00174,0.10296222382037773,destabilizing
+DDX6,PPM1E,0.1013677084024496,destabilizing
+DDX6,ARL3,0.05877417239451922,destabilizing
+DDX6,MBD5,0.07458502840973232,destabilizing
+DDX6,ELAVL3,0.11838928414234048,destabilizing
+DDX6,SLIT2,0.11955604620421942,destabilizing
+DDX6,UNC5C,0.07426807922531646,destabilizing
+DDX6,CACNA2D3,-0.05042856656723013,stabilizing
+DDX6,ENOX1,0.1692512212166231,destabilizing
+DDX6,GPHN,0.06547466385333325,destabilizing
+DDX6,NAV3,0.10250784136098155,destabilizing
+DDX6,TOMM22,0.09562135991284415,destabilizing
+DDX6,MAGI2,0.06300326715381356,destabilizing
+DDX6,AKAP6,0.0856110763624479,destabilizing
+DDX6,ZBTB20,0.09407453101869635,destabilizing
+DDX6,GRIK2,0.08644519962565668,destabilizing
+DDX6,LRRC37A3,0.13213749893439777,destabilizing
+DDX6,EYS,0.08325507578979317,destabilizing
+DDX6,RBFOX1,-0.07530566935665506,stabilizing
+DDX6,MLLT3,0.1600181389773704,destabilizing
+DDX6,ADGRB3,0.06229846414202425,destabilizing
+DDX6,ROBO1,0.09259121738360972,destabilizing
+DDX6,PTPRD,0.07436681018502286,destabilizing
+DDX6,LARP1B,0.0664485724191172,destabilizing
+DDX17,TRERF1,0.17936595825103255,destabilizing
+DDX17,SORCS1,0.10308115659859111,destabilizing
+DDX17,FCHSD2,0.07054222012220379,destabilizing
+DDX17,PDE3A,0.16882171535565693,destabilizing
+DDX17,UNC79,0.16493762169560333,destabilizing
+DDX17,DOC2B,0.12112089361206463,destabilizing
+DDX17,TMTC2,0.14609176323464415,destabilizing
+DDX17,KALRN,0.10217418516785014,destabilizing
+DDX17,CHD1,0.06927374809501531,destabilizing
+DDX17,UBE2E2,0.06019056785649654,destabilizing
+DDX17,PPARD,0.09282650545581032,destabilizing
+DDX17,TOX,0.10378023331547513,destabilizing
+DDX17,RYR2,0.1616463995057224,destabilizing
+DDX17,MTMR7,0.14988395287880169,destabilizing
+DDX17,EIF4E,0.1550294395327502,destabilizing
+DDX17,EPB41L4B,0.09774479345227437,destabilizing
+DDX17,CACNA1B,0.07613942988972285,destabilizing
+DDX17,LRRTM4,0.11118739007744648,destabilizing
+DDX17,SIRPA,0.16614052127412549,destabilizing
+DDX17,PTEN,0.10893512211481732,destabilizing
+DDX17,FRY,0.17009668357217625,destabilizing
+DDX17,MACROD2,0.14866437236015495,destabilizing
+DDX17,SHANK2,0.2546748578169595,destabilizing
+DDX17,CDK12,0.16479459361240076,destabilizing
+DDX17,BMPR1B,0.05666031805012449,destabilizing
+DDX17,RFX7,0.17188489318412706,destabilizing
+DDX17,UBR5,0.0763292007654897,destabilizing
+DDX17,JARID2,0.06797956020232837,destabilizing
+DDX17,MPHOSPH8,0.0903560960816566,destabilizing
+DDX17,DIP2C,0.12916859200242795,destabilizing
+DDX17,UBR3,0.15245728837226505,destabilizing
+DDX17,MGAT5,0.05463150745475847,destabilizing
+DDX17,DLG2,0.11056670242384688,destabilizing
+DDX17,CHST12,0.20045817331162036,destabilizing
+DDX17,EML5,0.15867278945720392,destabilizing
+DDX17,CENPP,0.20842464201755967,destabilizing
+DDX17,PSME4,0.14752485868981055,destabilizing
+DDX17,TMEM106B,0.17452493459820634,destabilizing
+DDX17,EPHA5,0.10565479531581318,destabilizing
+DDX17,KCNB2,0.13563703281604847,destabilizing
+DDX17,ZNF83,0.10368915052026695,destabilizing
+DDX17,ZNF521,0.08394102634313043,destabilizing
+DDX17,PLEKHA5,0.09749301263278354,destabilizing
+DDX17,NOVA1,0.18508831993133076,destabilizing
+DDX17,CCNY,0.17852808631180758,destabilizing
+DDX17,ARIH1,0.13579720758074756,destabilizing
+DDX17,EPB41L5,0.08401664004788424,destabilizing
+DDX17,GPR158,0.16278926756376574,destabilizing
+DDX17,NCOA2,0.10510632199264384,destabilizing
+DDX17,ALK,0.16050649423995308,destabilizing
+DDX17,ACACA,0.07166132639677969,destabilizing
+DDX17,ARHGAP26,0.0690600283288032,destabilizing
+DDX17,IFT172,0.10459249516493377,destabilizing
+DDX17,CCNT1,0.055924608990693445,destabilizing
+DDX17,DTWD2,0.1943897897049406,destabilizing
+DDX17,SIK3,0.1488111369958518,destabilizing
+DDX17,CPEB3,0.15324257650933956,destabilizing
+DDX17,XKR6,0.16630594467371126,destabilizing
+DDX17,CADPS,0.0880586074792473,destabilizing
+DDX17,FGF13,0.06383926792171567,destabilizing
+DDX17,TCF20,0.17270841339201592,destabilizing
+DDX17,CDKAL1,0.12852094315632237,destabilizing
+DDX17,DGKI,0.10607684805166878,destabilizing
+DDX17,EXOC6B,0.17099261450946837,destabilizing
+DDX17,MAGI3,0.1368058468067738,destabilizing
+DDX17,SBF2,0.06393444370332695,destabilizing
+DDX17,INPP4B,0.13769173103516424,destabilizing
+DDX17,PTPRS,0.17913841420490795,destabilizing
+DDX17,CBFA2T2,0.06500967536186206,destabilizing
+DDX17,SPDYE3,0.12311643891421982,destabilizing
+DDX17,TMEM178B,0.06589138397980801,destabilizing
+DDX17,DMD,0.21943645524337588,destabilizing
+DDX17,MCU,0.12732518742991847,destabilizing
+DDX17,SSH2,0.10866160479856893,destabilizing
+DDX17,DOCK3,0.14610721134709712,destabilizing
+DDX17,HS6ST3,0.12987889389486346,destabilizing
+DDX17,LPP,0.1685769022895398,destabilizing
+DDX17,STAG1,0.12901529531810635,destabilizing
+DDX17,CAPZA2,0.10446325440025059,destabilizing
+DDX17,PHACTR1,0.07753789938384921,destabilizing
+DDX17,UBE2R2,0.1269855576130634,destabilizing
+DDX17,GTF2IRD1,0.12622778014901873,destabilizing
+DDX17,CCBE1,0.07140453270851768,destabilizing
+DDX17,VAPA,-0.056383447981935716,stabilizing
+DDX17,TTC28,0.1057035948363843,destabilizing
+DDX17,RIMS2,0.08074639243405862,destabilizing
+DDX17,BTBD9,0.13736069406594534,destabilizing
+DDX17,CNGB1,0.1582360280554781,destabilizing
+DDX17,FMN2,0.1042794273182335,destabilizing
+DDX17,ENSG00000228222,0.24683579011156892,destabilizing
+DDX17,PRKN,0.2016621595875676,destabilizing
+DDX17,RASA2,0.09903955795305161,destabilizing
+DDX17,FRMD4A,0.0838914543173216,destabilizing
+DDX17,CAMK1D,0.07687388285775001,destabilizing
+DDX17,SEMA6D,0.106588723645623,destabilizing
+DDX17,WIPF2,0.10862684831791808,destabilizing
+DDX17,DLEU1,0.1716035241120241,destabilizing
+DDX17,TSHZ2,0.0888190508580098,destabilizing
+DDX17,MED13L,0.07153934988823675,destabilizing
+DDX17,KAZN,0.1326392754252293,destabilizing
+DDX17,FRMD5,0.16127801172883488,destabilizing
+DDX17,LINC00174,0.08194181041297584,destabilizing
+DDX17,PPM1E,0.13195395842597163,destabilizing
+DDX17,MBD5,0.10887688848928663,destabilizing
+DDX17,ELAVL3,0.09194783933255775,destabilizing
+DDX17,SLIT2,0.18848575013132574,destabilizing
+DDX17,CLASP1,0.07612460138658354,destabilizing
+DDX17,UNC5C,0.14178308024152902,destabilizing
+DDX17,CACNA2D3,-0.05855642518588489,stabilizing
+DDX17,RC3H1,0.07830043555710606,destabilizing
+DDX17,NEGR1,0.13830217729754707,destabilizing
+DDX17,ENOX1,0.22133988067247123,destabilizing
+DDX17,SCUBE1,0.06155290313885961,destabilizing
+DDX17,GPHN,0.1012046230562703,destabilizing
+DDX17,NAV3,0.14036861244901494,destabilizing
+DDX17,EBF1,0.05775043615716589,destabilizing
+DDX17,TOMM22,0.11829509463499234,destabilizing
+DDX17,MBNL2,0.07053797149460053,destabilizing
+DDX17,ANKFN1,0.06265817770525493,destabilizing
+DDX17,MAGI2,0.05336784858729597,destabilizing
+DDX17,AKAP6,0.11300577188088569,destabilizing
+DDX17,ZBTB20,0.11545663100743661,destabilizing
+DDX17,GRIK2,0.12874739059413712,destabilizing
+DDX17,SOX5,0.09479237090797465,destabilizing
+DDX17,LRRC37A3,0.17590376798971125,destabilizing
+DDX17,EYS,0.07527709887646059,destabilizing
+DDX17,ARID1B,0.09025038023247274,destabilizing
+DDX17,PRKCE,0.09590127508711174,destabilizing
+DDX17,RBFOX1,-0.07345862824114138,stabilizing
+DDX17,MLLT3,0.16134862407905076,destabilizing
+DDX17,FMN1,0.061144548329201694,destabilizing
+DDX17,ADGRB3,0.08021678285684526,destabilizing
+DDX17,ROBO1,0.14711085567719642,destabilizing
+DDX17,SYPL1,0.06890204108704623,destabilizing
+DDX17,PTPRD,0.10187326855874194,destabilizing
+DDX17,FAM155A,0.1629114729022714,destabilizing
+DDX17,LARP1B,0.12344355060290368,destabilizing
+DHX9,UNC79,0.09191554061833354,destabilizing
+DHX9,DOC2B,0.06919754104164517,destabilizing
+DHX9,FRY,0.11575106847966275,destabilizing
+DHX9,MACROD2,0.11051121862665687,destabilizing
+DHX9,CDK12,0.11882101240910968,destabilizing
+DHX9,EML5,0.10119926525019203,destabilizing
+DHX9,CENPP,0.15201391384513893,destabilizing
+DHX9,PSME4,0.08250121805025136,destabilizing
+DHX9,KCNB2,0.12475964303888186,destabilizing
+DHX9,ZNF83,0.07010344083721703,destabilizing
+DHX9,SOX6,0.07246844046024502,destabilizing
+DHX9,CCNY,0.08467713329665147,destabilizing
+DHX9,GPR158,0.08341699460921523,destabilizing
+DHX9,ALK,0.12346339726200561,destabilizing
+DHX9,DTWD2,0.1781694082222151,destabilizing
+DHX9,CPEB3,0.12533099684414686,destabilizing
+DHX9,XKR6,0.08924058562981516,destabilizing
+DHX9,TCF20,0.08663346315078002,destabilizing
+DHX9,EXOC6B,0.10414529727346354,destabilizing
+DHX9,MAGI3,0.09965081834798013,destabilizing
+DHX9,DMD,0.10173510712400904,destabilizing
+DHX9,DOCK3,0.08873862352520377,destabilizing
+DHX9,ENSG00000228222,0.116268958585847,destabilizing
+DHX9,RASA2,0.08232435798178783,destabilizing
+DHX9,WIPF2,0.0867678285323384,destabilizing
+DHX9,LINC00174,0.06163382848508832,destabilizing
+DHX9,MBD5,0.07299690013917047,destabilizing
+DHX9,ELAVL3,0.07546294460019073,destabilizing
+DHX9,UNC5C,0.06785036016687032,destabilizing
+DHX9,NEGR1,0.07732765984217034,destabilizing
+DHX9,ENOX1,0.10850884440502559,destabilizing
+DHX9,LRRC37A3,0.0954634062720427,destabilizing
+DHX9,MLLT3,0.13711772850320053,destabilizing
+DHX9,SYPL1,0.05465111089545645,destabilizing
+EIF4E,EIF4E,-0.2749728667248344,stabilizing
+LARP4,FRY,0.08692430285365423,destabilizing
+LARP4,SHANK2,0.1134728873574073,destabilizing
+LARP4,KCNB2,0.11041326652984523,destabilizing
+LARP4,MAGI3,0.07405299068730258,destabilizing
+LARP4,CNGB1,0.09139342638378636,destabilizing
+LARP4,RASA2,0.06723982409218594,destabilizing
+LARP4,FRMD5,0.06455665355849163,destabilizing
+LARP4,MLLT3,0.08070562754407916,destabilizing
+LARP6,UNC79,0.09147200189425977,destabilizing
+LARP6,MACROD2,0.06444643548958412,destabilizing
+LARP6,CPEB3,0.11121372148466373,destabilizing
+LARP6,UNC5C,0.06951542915037964,destabilizing
+LARP6,NEGR1,0.086344920920756,destabilizing
+LARP7,TRERF1,0.1304268537467488,destabilizing
+LARP7,SORCS1,0.08409381894512227,destabilizing
+LARP7,UNC79,0.14435760421108743,destabilizing
+LARP7,DOC2B,0.0728797633193181,destabilizing
+LARP7,TMTC2,0.10747112385824346,destabilizing
+LARP7,KALRN,0.0787214088869397,destabilizing
+LARP7,CHD1,0.07550834637138343,destabilizing
+LARP7,MTMR7,0.1105062491625736,destabilizing
+LARP7,EIF4E,0.1366798727303677,destabilizing
+LARP7,EPB41L4B,0.07517236437029509,destabilizing
+LARP7,CACNA1B,0.07057161016672146,destabilizing
+LARP7,TBC1D5,0.054692358944594614,destabilizing
+LARP7,LRRTM4,0.07073515413106249,destabilizing
+LARP7,PTEN,0.0907335233271222,destabilizing
+LARP7,FRY,0.12717101676781628,destabilizing
+LARP7,MACROD2,0.13001301656066572,destabilizing
+LARP7,SHANK2,0.15224604532139374,destabilizing
+LARP7,CDK12,0.17904693362014737,destabilizing
+LARP7,RFX7,0.10685207301917322,destabilizing
+LARP7,JARID2,0.05529923349633873,destabilizing
+LARP7,MPHOSPH8,0.11559731383571954,destabilizing
+LARP7,DIP2C,0.08878270688956136,destabilizing
+LARP7,UBR3,0.07385656285866202,destabilizing
+LARP7,DLG2,0.08479961676012042,destabilizing
+LARP7,CHST12,0.21030152882708317,destabilizing
+LARP7,EML5,0.1413186198297676,destabilizing
+LARP7,CENPP,0.12048704862253282,destabilizing
+LARP7,PSME4,0.08965230986717772,destabilizing
+LARP7,TMEM106B,0.11489503171447879,destabilizing
+LARP7,EPHA5,0.09194728578324152,destabilizing
+LARP7,KCNB2,0.13053376323638372,destabilizing
+LARP7,ZNF83,0.07489245585863463,destabilizing
+LARP7,SOX6,0.0784902169318921,destabilizing
+LARP7,ZNF521,0.08324142110950906,destabilizing
+LARP7,NOVA1,0.12317167221701783,destabilizing
+LARP7,CCNY,0.10296886207212852,destabilizing
+LARP7,ARIH1,0.0919009142788519,destabilizing
+LARP7,EPB41L5,0.08561854926279999,destabilizing
+LARP7,GPR158,0.12274766992122242,destabilizing
+LARP7,NCOA2,0.10420629522695495,destabilizing
+LARP7,ALK,0.13674388145016764,destabilizing
+LARP7,ACACA,0.0703217083762276,destabilizing
+LARP7,IFT172,0.10516870873425979,destabilizing
+LARP7,CCNT1,0.07035481664974552,destabilizing
+LARP7,SIK3,0.07584177377399585,destabilizing
+LARP7,CPEB3,0.1280774978796475,destabilizing
+LARP7,CADM2,0.05938079250316794,destabilizing
+LARP7,XKR6,0.11972302920399039,destabilizing
+LARP7,RMND5A,0.05350934965573967,destabilizing
+LARP7,CADPS,0.07338911533722764,destabilizing
+LARP7,TCF20,0.10864807635231184,destabilizing
+LARP7,CDKAL1,0.08435424041855993,destabilizing
+LARP7,DGKI,0.10389430750200315,destabilizing
+LARP7,EXOC6B,0.12813478653187876,destabilizing
+LARP7,MAGI3,0.10612353453440641,destabilizing
+LARP7,SBF2,0.059166726297837896,destabilizing
+LARP7,INPP4B,0.12003866217302185,destabilizing
+LARP7,PTPRS,0.13757480074535924,destabilizing
+LARP7,CBFA2T2,0.061678323595797196,destabilizing
+LARP7,SPDYE3,0.0986776444706056,destabilizing
+LARP7,DMD,0.1858745307836745,destabilizing
+LARP7,MCU,0.07903560387914105,destabilizing
+LARP7,SSH2,0.09422693465712433,destabilizing
+LARP7,DOCK3,0.1273890593142212,destabilizing
+LARP7,HS6ST3,0.12365796732907265,destabilizing
+LARP7,LPP,0.09991652728723464,destabilizing
+LARP7,CAPZA2,0.10111862841865008,destabilizing
+LARP7,ADGRL3,0.06379988234043808,destabilizing
+LARP7,UBE2R2,0.08350441075643511,destabilizing
+LARP7,GTF2IRD1,0.11062268904330541,destabilizing
+LARP7,CCBE1,0.060275670351042906,destabilizing
+LARP7,TTC28,0.07641460664775304,destabilizing
+LARP7,RIMS2,0.07131480730216606,destabilizing
+LARP7,TRIO,0.057014193824023965,destabilizing
+LARP7,BTBD9,0.10221103843959212,destabilizing
+LARP7,CNGB1,0.11862023071555593,destabilizing
+LARP7,FMN2,0.08877065727914477,destabilizing
+LARP7,ENSG00000228222,0.17464377623186103,destabilizing
+LARP7,PRKN,0.14826981586079513,destabilizing
+LARP7,RASA2,0.11298407378823387,destabilizing
+LARP7,PPP1R12B,0.08640743538385665,destabilizing
+LARP7,FRMD4A,0.09446710108786358,destabilizing
+LARP7,SEMA6D,0.08187935857073794,destabilizing
+LARP7,WIPF2,0.122297327408666,destabilizing
+LARP7,DLEU1,0.15543729624167385,destabilizing
+LARP7,TSHZ2,0.06985040671942931,destabilizing
+LARP7,MED13L,0.06500540402445609,destabilizing
+LARP7,KAZN,0.08954183476917371,destabilizing
+LARP7,FRMD5,0.10044790895071748,destabilizing
+LARP7,LINC00174,0.09979043138869115,destabilizing
+LARP7,PPM1E,0.10822308463921247,destabilizing
+LARP7,ARL3,0.07019959463379204,destabilizing
+LARP7,MBD5,0.07851786485765377,destabilizing
+LARP7,ELAVL3,0.10852978648464556,destabilizing
+LARP7,SLIT2,0.16101022706234228,destabilizing
+LARP7,CLASP1,0.0770038955570518,destabilizing
+LARP7,UNC5C,0.10931414382085165,destabilizing
+LARP7,CACNA2D3,-0.053741221836578514,stabilizing
+LARP7,RC3H1,0.07569954816406939,destabilizing
+LARP7,NEGR1,0.09329597201540003,destabilizing
+LARP7,ENOX1,0.17178027775460525,destabilizing
+LARP7,SCUBE1,0.08599549738120586,destabilizing
+LARP7,GPHN,0.06363457942051541,destabilizing
+LARP7,NAV3,0.14092038713103158,destabilizing
+LARP7,TOMM22,0.13759048182606634,destabilizing
+LARP7,LSAMP,0.07403568434254335,destabilizing
+LARP7,AKAP6,0.0781729333998656,destabilizing
+LARP7,TMED2,0.07776054800602974,destabilizing
+LARP7,ZBTB20,0.10915393035034496,destabilizing
+LARP7,GRIK2,0.09503804728347134,destabilizing
+LARP7,LRRC37A3,0.1261702505355187,destabilizing
+LARP7,EYS,0.07049768758354732,destabilizing
+LARP7,ARID1B,0.06471003504068587,destabilizing
+LARP7,RBFOX1,-0.07282070514951568,stabilizing
+LARP7,SDK1,0.062475203958762715,destabilizing
+LARP7,MLLT3,0.16368020242242037,destabilizing
+LARP7,ADGRB3,0.05955683457887009,destabilizing
+LARP7,ROBO1,0.08857126528428709,destabilizing
+LARP7,SYPL1,0.057094834384395256,destabilizing
+LARP7,PTPRD,0.10364863439727534,destabilizing
+LARP7,FAM155A,0.11518123393442459,destabilizing
+LARP7,LARP1B,0.08763859234510028,destabilizing
+NCL,TRERF1,0.17295130003785603,destabilizing
+NCL,SORCS1,0.12515659168204318,destabilizing
+NCL,NCOA1,0.06522525857818863,destabilizing
+NCL,FCHSD2,0.08286760865120792,destabilizing
+NCL,PDE3A,0.14584243829276178,destabilizing
+NCL,UNC79,0.1813368014878177,destabilizing
+NCL,DOC2B,0.13128354864578562,destabilizing
+NCL,TMTC2,0.19296636663490135,destabilizing
+NCL,KALRN,0.09081009838692246,destabilizing
+NCL,CHD1,0.09676646185671484,destabilizing
+NCL,UBE2E2,0.07112370790396486,destabilizing
+NCL,PPARD,0.10870852700503598,destabilizing
+NCL,TOX,0.08471782445372558,destabilizing
+NCL,BRAF,0.05515929056290525,destabilizing
+NCL,RYR2,0.16318308338338863,destabilizing
+NCL,MTMR7,0.17594089003456972,destabilizing
+NCL,EIF4E,0.1502490546167142,destabilizing
+NCL,SOX11,0.06313250731376818,destabilizing
+NCL,EPB41L4B,0.09251981661364699,destabilizing
+NCL,CACNA1B,0.10329593887048955,destabilizing
+NCL,LRRTM4,0.11225906604322994,destabilizing
+NCL,PTEN,0.10495095430473139,destabilizing
+NCL,FRY,0.17971624637741082,destabilizing
+NCL,MACROD2,0.1771108322526778,destabilizing
+NCL,SHANK2,0.2266350176030162,destabilizing
+NCL,CDK12,0.20483138507065612,destabilizing
+NCL,RFX7,0.1680033667460092,destabilizing
+NCL,JARID2,0.08350741481660005,destabilizing
+NCL,MPHOSPH8,0.11264505565012586,destabilizing
+NCL,DIP2C,0.09349090908696382,destabilizing
+NCL,UBR3,0.11669690664176824,destabilizing
+NCL,DLG2,0.09970667675278591,destabilizing
+NCL,CHST12,0.21742345838508215,destabilizing
+NCL,EML5,0.17210983572886746,destabilizing
+NCL,CENPP,0.2712400241837624,destabilizing
+NCL,PSME4,0.14659751239030516,destabilizing
+NCL,TMEM106B,0.16030745897462267,destabilizing
+NCL,EPHA5,0.14256175422070774,destabilizing
+NCL,KCNB2,0.19121522230640164,destabilizing
+NCL,ZNF83,0.11610776186461265,destabilizing
+NCL,SOX6,0.0877033490883364,destabilizing
+NCL,ZNF521,0.136160501877904,destabilizing
+NCL,PLEKHA5,0.06823351524726548,destabilizing
+NCL,NOVA1,0.2139847941174402,destabilizing
+NCL,CCNY,0.15447632615354545,destabilizing
+NCL,ARIH1,0.14753646733794548,destabilizing
+NCL,EPB41L5,0.0967242696361523,destabilizing
+NCL,GPR158,0.16230224651510047,destabilizing
+NCL,NCOA2,0.10824828282937002,destabilizing
+NCL,ALK,0.21846216284353623,destabilizing
+NCL,ACACA,0.05776673165662883,destabilizing
+NCL,IFT172,0.14828222376817105,destabilizing
+NCL,CCNT1,0.08398154709940314,destabilizing
+NCL,DTWD2,0.22282929775794644,destabilizing
+NCL,SIK3,0.1572473690541032,destabilizing
+NCL,CPEB3,0.15269113681731533,destabilizing
+NCL,CADM2,0.07801202547297531,destabilizing
+NCL,XKR6,0.1892426710953384,destabilizing
+NCL,CADPS,0.10264680595097407,destabilizing
+NCL,TCF20,0.14690075511643416,destabilizing
+NCL,CDKAL1,0.11751022165306528,destabilizing
+NCL,DGKI,0.12129381867518306,destabilizing
+NCL,EXOC6B,0.20589974050678506,destabilizing
+NCL,MAGI3,0.191470174617459,destabilizing
+NCL,SBF2,0.08296610016720982,destabilizing
+NCL,INPP4B,0.1351813995219388,destabilizing
+NCL,PTPRS,0.22510959707931247,destabilizing
+NCL,CBFA2T2,0.07128657898966052,destabilizing
+NCL,SPDYE3,0.1166695809167942,destabilizing
+NCL,TMEM178B,0.0877328311435933,destabilizing
+NCL,DMD,0.2219387421720987,destabilizing
+NCL,MCU,0.1475888030903155,destabilizing
+NCL,SSH2,0.12431662716921921,destabilizing
+NCL,DOCK3,0.1924078896965684,destabilizing
+NCL,HS6ST3,0.097515551489632,destabilizing
+NCL,LPP,0.16474283976400508,destabilizing
+NCL,STAG1,0.10908957413060434,destabilizing
+NCL,CAPZA2,0.1436551751333912,destabilizing
+NCL,ADGRL3,0.08063166599976616,destabilizing
+NCL,PHACTR1,0.07103840538099306,destabilizing
+NCL,UBE2R2,0.15399404892400978,destabilizing
+NCL,GTF2IRD1,0.15291445374610663,destabilizing
+NCL,TTC28,0.13782411159070687,destabilizing
+NCL,SBNO1,0.07951137593902632,destabilizing
+NCL,RIMS2,0.0818844372294851,destabilizing
+NCL,BTBD9,0.1442574608662313,destabilizing
+NCL,CNGB1,0.13423802630034803,destabilizing
+NCL,FMN2,0.11308358938745779,destabilizing
+NCL,ENSG00000228222,0.24229867387917747,destabilizing
+NCL,SYN3,0.06475117375202234,destabilizing
+NCL,PRKN,0.18934797785187343,destabilizing
+NCL,RASA2,0.151456754835021,destabilizing
+NCL,FRMD4A,0.10485760030415797,destabilizing
+NCL,SEMA6D,0.1279765290568121,destabilizing
+NCL,WIPF2,0.1414369218879598,destabilizing
+NCL,DLEU1,0.18718031882813133,destabilizing
+NCL,TSHZ2,0.1034341036311312,destabilizing
+NCL,MED13L,0.06531207757434841,destabilizing
+NCL,KAZN,0.11800722572861366,destabilizing
+NCL,KANSL1,0.09176428086911084,destabilizing
+NCL,FRMD5,0.1322545561802574,destabilizing
+NCL,LINC00174,0.11679534668198455,destabilizing
+NCL,PPM1E,0.11880508884334536,destabilizing
+NCL,ARL3,0.1222710005518293,destabilizing
+NCL,MBD5,0.11668242756609172,destabilizing
+NCL,ELAVL3,0.13988418595868576,destabilizing
+NCL,SLIT2,0.17633244977149196,destabilizing
+NCL,CLASP1,0.0825476380609461,destabilizing
+NCL,UNC5C,0.1487496721248927,destabilizing
+NCL,CACNA2D3,-0.07090396563059786,stabilizing
+NCL,RC3H1,0.07261565160927812,destabilizing
+NCL,NEGR1,0.20711537651199052,destabilizing
+NCL,ENOX1,0.19592029103025546,destabilizing
+NCL,SCUBE1,0.07133735169252033,destabilizing
+NCL,GPHN,0.0981093913045824,destabilizing
+NCL,NAV3,0.13995655071316052,destabilizing
+NCL,TOMM22,0.16460591044302086,destabilizing
+NCL,ANKFN1,0.05485668548540059,destabilizing
+NCL,MAGI2,0.07442787206408727,destabilizing
+NCL,LSAMP,0.07968432960785655,destabilizing
+NCL,AKAP6,0.12876379300379961,destabilizing
+NCL,ZBTB20,0.14335283677267202,destabilizing
+NCL,GRIK2,0.1174515338477924,destabilizing
+NCL,LRRC37A3,0.1734252190755852,destabilizing
+NCL,EYS,0.10877390478361612,destabilizing
+NCL,ARID1B,0.10013054732649342,destabilizing
+NCL,PRKCE,0.08076254796137122,destabilizing
+NCL,RBFOX1,-0.08715430061020525,stabilizing
+NCL,SDK1,0.07372025352422401,destabilizing
+NCL,MLLT3,0.21113029236467254,destabilizing
+NCL,ADGRB3,0.09786999959527796,destabilizing
+NCL,ROBO1,0.13326793347037547,destabilizing
+NCL,SYPL1,0.07748282585611242,destabilizing
+NCL,PTPRD,0.10972712363783592,destabilizing
+NCL,FAM155A,0.1642476432637018,destabilizing
+NCL,LARP1B,0.12052804855013612,destabilizing
+NPM1,TRERF1,0.11922087766088955,destabilizing
+NPM1,SORCS1,0.07102730454192212,destabilizing
+NPM1,PDE3A,0.1417869697251611,destabilizing
+NPM1,UNC79,0.1441477490640653,destabilizing
+NPM1,DOC2B,0.10111361999026651,destabilizing
+NPM1,TMTC2,0.12997736614346506,destabilizing
+NPM1,MTMR7,0.0900667835796975,destabilizing
+NPM1,EIF4E,0.11175321439286173,destabilizing
+NPM1,CACNA1B,0.059896246669046055,destabilizing
+NPM1,SIRPA,0.11147384291712142,destabilizing
+NPM1,FRY,0.13163434912087554,destabilizing
+NPM1,MACROD2,0.09875324617551068,destabilizing
+NPM1,SHANK2,0.1440562833276198,destabilizing
+NPM1,CDK12,0.12542519338840635,destabilizing
+NPM1,RFX7,0.12782362276571568,destabilizing
+NPM1,MPHOSPH8,0.1030555350738003,destabilizing
+NPM1,DIP2C,0.10586625927774866,destabilizing
+NPM1,UBR3,0.07728085894028068,destabilizing
+NPM1,MGAT5,0.0546372715548766,destabilizing
+NPM1,DLG2,0.09337976478053026,destabilizing
+NPM1,CHST12,0.16644170593236704,destabilizing
+NPM1,EML5,0.11629719433640176,destabilizing
+NPM1,CENPP,0.11969441120131519,destabilizing
+NPM1,PSME4,0.09778655240702074,destabilizing
+NPM1,TMEM106B,0.138856061193793,destabilizing
+NPM1,EPHA5,0.09515745563119107,destabilizing
+NPM1,KCNB2,0.1256367230610996,destabilizing
+NPM1,ZNF521,0.09539232970722018,destabilizing
+NPM1,PLEKHA5,0.07282216912083808,destabilizing
+NPM1,NOVA1,0.10133936166222794,destabilizing
+NPM1,CCNY,0.10140092257754497,destabilizing
+NPM1,ARIH1,0.07855893919392691,destabilizing
+NPM1,EPB41L5,0.07402789129333277,destabilizing
+NPM1,GPR158,0.10985620366797935,destabilizing
+NPM1,NCOA2,0.0789225469426089,destabilizing
+NPM1,ALK,0.10844640155473693,destabilizing
+NPM1,IFT172,0.09407992510221112,destabilizing
+NPM1,DTWD2,0.14290606927885577,destabilizing
+NPM1,SIK3,0.08570433032835881,destabilizing
+NPM1,CPEB3,0.11516440665671474,destabilizing
+NPM1,XKR6,0.09902230745308858,destabilizing
+NPM1,TCF20,0.11849720933929508,destabilizing
+NPM1,CDKAL1,0.06724692239160715,destabilizing
+NPM1,DGKI,0.0796014112297712,destabilizing
+NPM1,EXOC6B,0.14655956697931413,destabilizing
+NPM1,MAGI3,0.10767373993105726,destabilizing
+NPM1,SBF2,0.06251580190719767,destabilizing
+NPM1,INPP4B,0.10086416398142574,destabilizing
+NPM1,ERC1,0.05642554723949178,destabilizing
+NPM1,PTPRS,0.12597551829716858,destabilizing
+NPM1,CBFA2T2,0.06590952713248922,destabilizing
+NPM1,SPDYE3,0.08246105909098501,destabilizing
+NPM1,DMD,0.13363962355749998,destabilizing
+NPM1,MCU,0.1107283945173135,destabilizing
+NPM1,SSH2,0.09568725809021587,destabilizing
+NPM1,DOCK3,0.12637858182257092,destabilizing
+NPM1,HS6ST3,0.11712945624208522,destabilizing
+NPM1,LPP,0.13820534733064704,destabilizing
+NPM1,STAG1,0.08192334011416254,destabilizing
+NPM1,CAPZA2,0.10529965739027931,destabilizing
+NPM1,GTF2IRD1,0.06977163568246394,destabilizing
+NPM1,CCBE1,0.051237964550155,destabilizing
+NPM1,TRIO,0.056167411971218946,destabilizing
+NPM1,BTBD9,0.10737786226915502,destabilizing
+NPM1,CNGB1,0.11735165525532658,destabilizing
+NPM1,FMN2,0.0691444546429003,destabilizing
+NPM1,ENSG00000228222,0.179684288876311,destabilizing
+NPM1,PRKN,0.14220536181211835,destabilizing
+NPM1,RASA2,0.11038976667839141,destabilizing
+NPM1,PPP1R12B,0.06813677541920404,destabilizing
+NPM1,WIPF2,0.10013942374921679,destabilizing
+NPM1,DLEU1,0.17610820507832436,destabilizing
+NPM1,KAZN,0.08692643198183359,destabilizing
+NPM1,FRMD5,0.09608121447507957,destabilizing
+NPM1,LINC00174,0.06194008764772754,destabilizing
+NPM1,PPM1E,0.07371463835094763,destabilizing
+NPM1,ARL3,0.0700802082344431,destabilizing
+NPM1,MBD5,0.07611505198986666,destabilizing
+NPM1,ELAVL3,0.08688571290825764,destabilizing
+NPM1,SLIT2,0.13164298005100386,destabilizing
+NPM1,UNC5C,0.10154774079845323,destabilizing
+NPM1,NEGR1,0.0869657447983242,destabilizing
+NPM1,ENOX1,0.13726533005434602,destabilizing
+NPM1,SCUBE1,0.0627165615677879,destabilizing
+NPM1,GPHN,0.1047893545419926,destabilizing
+NPM1,NAV3,0.09561307113041405,destabilizing
+NPM1,TOMM22,0.12691221296246813,destabilizing
+NPM1,AKAP6,0.09740645295251868,destabilizing
+NPM1,TMED2,0.07538224062118541,destabilizing
+NPM1,ZBTB20,0.07829770860625927,destabilizing
+NPM1,GRIK2,0.11975006477490832,destabilizing
+NPM1,SOX5,0.07468499449619069,destabilizing
+NPM1,LRRC37A3,0.1108627811086949,destabilizing
+NPM1,EYS,0.06530992419195618,destabilizing
+NPM1,MLLT3,0.14037889146460356,destabilizing
+NPM1,FMN1,0.06926550227441391,destabilizing
+NPM1,ADGRB3,0.07735416210729987,destabilizing
+NPM1,ROBO1,0.07739535689106691,destabilizing
+NPM1,PTPRD,0.06679036981421532,destabilizing
+NPM1,FAM155A,0.12382737575589126,destabilizing
+NPM1,LARP1B,0.10018276274403148,destabilizing
+YBX1,TRERF1,0.4429706355011732,destabilizing
+YBX1,SORCS1,0.3031170899856172,destabilizing
+YBX1,NCOA1,0.10722041378646789,destabilizing
+YBX1,COPA,0.20889777219090497,destabilizing
+YBX1,FCHSD2,0.20285088933597745,destabilizing
+YBX1,PDE3A,0.39892351414478616,destabilizing
+YBX1,UNC79,0.4468640780612493,destabilizing
+YBX1,DOC2B,0.34724721739843273,destabilizing
+YBX1,TMTC2,0.432240663810082,destabilizing
+YBX1,KALRN,0.2876320959757604,destabilizing
+YBX1,CHD1,0.22068689306210687,destabilizing
+YBX1,PAK3,0.12009348791367389,destabilizing
+YBX1,UBE2E2,0.1964799700160911,destabilizing
+YBX1,PPARD,0.2416893540662768,destabilizing
+YBX1,TOX,0.17701158669695058,destabilizing
+YBX1,BRAF,0.16923611311071265,destabilizing
+YBX1,RYR2,0.41894351179018596,destabilizing
+YBX1,ZNF609,0.09582562032814379,destabilizing
+YBX1,MTMR7,0.4697199809251823,destabilizing
+YBX1,EIF4E,0.42234793378195007,destabilizing
+YBX1,SOX11,0.14279560087602072,destabilizing
+YBX1,EPB41L4B,0.26325448573417903,destabilizing
+YBX1,CACNA1B,0.28291151938167475,destabilizing
+YBX1,TBC1D5,0.16126366306785403,destabilizing
+YBX1,WSB1,0.08260569029928964,destabilizing
+YBX1,LRRTM4,0.2962830048011456,destabilizing
+YBX1,SIRPA,0.3521721660271727,destabilizing
+YBX1,MAP4K3,0.0579721891390913,destabilizing
+YBX1,PTEN,0.2815846451085278,destabilizing
+YBX1,SPPL3,0.060475822527414305,destabilizing
+YBX1,FRY,0.48251746856508176,destabilizing
+YBX1,RUNX1T1,0.12750146137736104,destabilizing
+YBX1,MACROD2,0.3908676077503305,destabilizing
+YBX1,FOXN3,0.11102319340348646,destabilizing
+YBX1,SHANK2,0.44655063632728204,destabilizing
+YBX1,CDK12,0.5617810138289562,destabilizing
+YBX1,BMPR1B,0.06891668663190331,destabilizing
+YBX1,RFX7,0.436958047416639,destabilizing
+YBX1,UBR5,0.19859929196842974,destabilizing
+YBX1,JARID2,0.22669847837541238,destabilizing
+YBX1,MPHOSPH8,0.3606589550338517,destabilizing
+YBX1,RGS7,-0.07396699100766382,stabilizing
+YBX1,DIP2C,0.2824799962989856,destabilizing
+YBX1,ZNF423,0.15880633673529676,destabilizing
+YBX1,UBR3,0.2648786312554502,destabilizing
+YBX1,MGAT5,0.15176513703435848,destabilizing
+YBX1,DLG2,0.29341559427255753,destabilizing
+YBX1,CHST12,0.6053634026223167,destabilizing
+YBX1,EML5,0.47165881306583446,destabilizing
+YBX1,CENPP,0.5083447826431625,destabilizing
+YBX1,PSME4,0.36801808948108344,destabilizing
+YBX1,TMEM106B,0.41396844416216216,destabilizing
+YBX1,RABGAP1L,0.09940079520956686,destabilizing
+YBX1,EPHA5,0.33615413370067887,destabilizing
+YBX1,KCNB2,0.46679722476385405,destabilizing
+YBX1,ZNF83,0.2705233871824004,destabilizing
+YBX1,SOX6,0.29198019646010553,destabilizing
+YBX1,ZNF521,0.35293802652605755,destabilizing
+YBX1,PLEKHA5,0.24704308302744227,destabilizing
+YBX1,NOVA1,0.4810228256506923,destabilizing
+YBX1,CCNY,0.3787937139798254,destabilizing
+YBX1,ARIH1,0.3041948990909779,destabilizing
+YBX1,FAM171B,0.1283403733480262,destabilizing
+YBX1,EPB41L5,0.29964883714243,destabilizing
+YBX1,GPR158,0.39167952378958887,destabilizing
+YBX1,NCOA2,0.26491370272904224,destabilizing
+YBX1,PRKCB,0.062011520588138865,destabilizing
+YBX1,ALK,0.5089596293477326,destabilizing
+YBX1,ACACA,0.1594793249825426,destabilizing
+YBX1,ARHGAP26,0.13517814372079892,destabilizing
+YBX1,CTNND2,0.14077352823715653,destabilizing
+YBX1,IFT172,0.410846681380846,destabilizing
+YBX1,CCNT1,0.2800883035725918,destabilizing
+YBX1,ENAH,0.06689387084685891,destabilizing
+YBX1,DTWD2,0.5650015302443335,destabilizing
+YBX1,SIK3,0.32442124156751284,destabilizing
+YBX1,CPEB3,0.4288595965828285,destabilizing
+YBX1,CADM2,0.19932837234378617,destabilizing
+YBX1,KIF26B,0.0602158533351067,destabilizing
+YBX1,XKR6,0.4399879888187944,destabilizing
+YBX1,RMND5A,0.173177289779795,destabilizing
+YBX1,CADPS,0.22165001544207166,destabilizing
+YBX1,FGF13,0.1668328380601423,destabilizing
+YBX1,TCF20,0.43269572042349447,destabilizing
+YBX1,CDKAL1,0.23007269249924509,destabilizing
+YBX1,DGKI,0.3229662023199598,destabilizing
+YBX1,EXOC6B,0.47715156857220875,destabilizing
+YBX1,MAGI3,0.41139079821687596,destabilizing
+YBX1,SBF2,0.2097736394729808,destabilizing
+YBX1,INPP4B,0.34944423207845415,destabilizing
+YBX1,ERC1,0.17044155325175703,destabilizing
+YBX1,PTPRS,0.40564039855774714,destabilizing
+YBX1,CBFA2T2,0.21823549206646306,destabilizing
+YBX1,SPDYE3,0.2869001103850262,destabilizing
+YBX1,TMEM178B,0.18369648359729399,destabilizing
+YBX1,KMT2C,0.09582660268841654,destabilizing
+YBX1,CACNA2D1,0.12999649372686287,destabilizing
+YBX1,DMD,0.5806894186565913,destabilizing
+YBX1,EIF4G3,0.147996416842234,destabilizing
+YBX1,MCU,0.3881146414564626,destabilizing
+YBX1,SSH2,0.31076303436958297,destabilizing
+YBX1,TCF12,0.06016946565846027,destabilizing
+YBX1,DOCK3,0.4425452737712667,destabilizing
+YBX1,HS6ST3,0.3428561395139238,destabilizing
+YBX1,LPP,0.4149127571183795,destabilizing
+YBX1,STAG1,0.2646389359968578,destabilizing
+YBX1,CAPZA2,0.3749513073051356,destabilizing
+YBX1,ADGRL3,0.2259866275911756,destabilizing
+YBX1,PHACTR1,0.22547751925169188,destabilizing
+YBX1,UBE2R2,0.37349731578543605,destabilizing
+YBX1,GTF2IRD1,0.32120428890881214,destabilizing
+YBX1,CCBE1,0.18104097403485903,destabilizing
+YBX1,FTX,0.12691823563091054,destabilizing
+YBX1,VAPA,0.14430868530788177,destabilizing
+YBX1,JMJD1C,0.11443904839660486,destabilizing
+YBX1,TTC28,0.27274318623408345,destabilizing
+YBX1,SBNO1,0.23798035490190103,destabilizing
+YBX1,RIMS2,0.24424622831777626,destabilizing
+YBX1,IGF1R,0.16160535790153965,destabilizing
+YBX1,TRIO,0.13439305102805585,destabilizing
+YBX1,KCND2,0.12529981112693073,destabilizing
+YBX1,BTBD9,0.35456568989913656,destabilizing
+YBX1,CNGB1,0.47128558654120734,destabilizing
+YBX1,FMN2,0.33210134790716295,destabilizing
+YBX1,ENSG00000228222,0.574341449908456,destabilizing
+YBX1,ATXN1,0.1411056627066632,destabilizing
+YBX1,SYN3,0.13740927012657247,destabilizing
+YBX1,PRKN,0.457342390293766,destabilizing
+YBX1,RASA2,0.422753453322649,destabilizing
+YBX1,PPP1R12B,0.33911843071936315,destabilizing
+YBX1,FRMD4A,0.31493741508530565,destabilizing
+YBX1,CAMK1D,0.1493939879568913,destabilizing
+YBX1,PARD3,0.11702448483587202,destabilizing
+YBX1,SEMA6D,0.3735270999462794,destabilizing
+YBX1,WIPF2,0.41454153533650867,destabilizing
+YBX1,WWOX,0.06264659588558232,destabilizing
+YBX1,DLEU1,0.5182997982790133,destabilizing
+YBX1,TSHZ2,0.21542060693289394,destabilizing
+YBX1,MED13L,0.24610440825181634,destabilizing
+YBX1,AFF3,0.12016720671642786,destabilizing
+YBX1,KAZN,0.3286264924236311,destabilizing
+YBX1,KANSL1,0.26505847881405953,destabilizing
+YBX1,FRMD5,0.29720186521511593,destabilizing
+YBX1,LINC00174,0.376435795828166,destabilizing
+YBX1,PPM1E,0.28499447726511884,destabilizing
+YBX1,ARL3,0.27840629200806694,destabilizing
+YBX1,MBD5,0.3183354919497761,destabilizing
+YBX1,ELAVL3,0.354614652445774,destabilizing
+YBX1,SLIT2,0.4853016845352639,destabilizing
+YBX1,SLC8A1,0.15030217934116827,destabilizing
+YBX1,CLASP1,0.26486076643888,destabilizing
+YBX1,DOCK4,0.07295862340969984,destabilizing
+YBX1,UNC5C,0.3755201468729097,destabilizing
+YBX1,CACNA2D3,-0.15797079759910101,stabilizing
+YBX1,RC3H1,0.24541247716804607,destabilizing
+YBX1,NEGR1,0.3943826575142822,destabilizing
+YBX1,ENOX1,0.5178736455212859,destabilizing
+YBX1,SCUBE1,0.22316132599387922,destabilizing
+YBX1,GPHN,0.3007940890487196,destabilizing
+YBX1,NAV3,0.4249611074090873,destabilizing
+YBX1,EBF1,0.18755916612861084,destabilizing
+YBX1,TOMM22,0.4424492162211266,destabilizing
+YBX1,MBNL2,0.17479103027469503,destabilizing
+YBX1,ANKFN1,0.14193111825865135,destabilizing
+YBX1,MAGI2,0.20009382174583135,destabilizing
+YBX1,LSAMP,0.2583724074012091,destabilizing
+YBX1,AKAP6,0.39610101569415795,destabilizing
+YBX1,TMED2,0.28408152116596314,destabilizing
+YBX1,ZBTB20,0.36753114341597143,destabilizing
+YBX1,GRIK2,0.32233911099436713,destabilizing
+YBX1,MAML3,0.05171003563992947,destabilizing
+YBX1,SOX5,0.26917381694777154,destabilizing
+YBX1,LRRC37A3,0.49057638586838853,destabilizing
+YBX1,TMEM132C,0.12458423923476251,destabilizing
+YBX1,EYS,0.29397700269834626,destabilizing
+YBX1,ARID1B,0.25695170471658746,destabilizing
+YBX1,PRKCE,0.25489021241439785,destabilizing
+YBX1,RBFOX1,-0.15700527243325943,stabilizing
+YBX1,SDK1,0.1916835423761,destabilizing
+YBX1,NRG1,0.166177037938796,destabilizing
+YBX1,RORA,0.06370263990940372,destabilizing
+YBX1,MLLT3,0.5436783030099039,destabilizing
+YBX1,AUTS2,0.05940871522724359,destabilizing
+YBX1,FMN1,0.20489471953343227,destabilizing
+YBX1,ADGRB3,0.20532445312810813,destabilizing
+YBX1,ROBO1,0.31414899004249175,destabilizing
+YBX1,SYPL1,0.2407101470851787,destabilizing
+YBX1,PTPRD,0.3396302499613022,destabilizing
+YBX1,FAM155A,0.41124132919649814,destabilizing
+YBX1,LARP1B,0.40482904941765596,destabilizing
+CCAR2,UNC79,0.09674946476211432,destabilizing
+CCAR2,SHANK2,0.10821308837695442,destabilizing
+CCAR2,MPHOSPH8,0.07024654682597582,destabilizing
+CCAR2,KCNB2,0.08651747827067234,destabilizing
+CCAR2,SOX6,0.0619986936457862,destabilizing
+CCAR2,ZNF521,0.07219914495830056,destabilizing
+CCAR2,GPR158,0.07237744230155262,destabilizing
+CCAR2,ALK,0.10227118322785338,destabilizing
+CCAR2,XKR6,0.07791660027785634,destabilizing
+CCAR2,DGKI,0.07420012334405471,destabilizing
+CCAR2,MAGI3,0.0725787107107941,destabilizing
+CCAR2,DMD,0.08546841401294106,destabilizing
+CCAR2,DOCK3,0.08468825061991841,destabilizing
+CCAR2,ARL3,0.058419265244502264,destabilizing
+CCAR2,MBD5,0.065348776930466,destabilizing
+CCAR2,ELAVL3,0.07202521288002887,destabilizing
+CCAR2,CLASP1,0.08920853713173423,destabilizing
+CCAR2,ZBTB20,0.07759860959645316,destabilizing
+CCAR2,LRRC37A3,0.07506369946111245,destabilizing
+CCAR2,MLLT3,0.11546196108765294,destabilizing
+RC3H1,DMD,0.07951506747049308,destabilizing
+RC3H1,RC3H1,-0.32682500602392733,stabilizing
+RC3H1,NEGR1,0.07815257484670499,destabilizing
+RC3H2,MACROD2,0.0753571021816648,destabilizing
+RC3H2,NOVA1,0.09752047860100703,destabilizing
+RC3H2,MCU,0.0703606975144726,destabilizing
+RC3H2,GRIK2,0.05975284831162621,destabilizing
+RC3H2,MLLT3,0.0926944963188838,destabilizing
+ZC3H14,SORCS1,0.062468408844763595,destabilizing
+ZC3H14,MTMR7,0.09085532882253476,destabilizing
+ZC3H14,MACROD2,0.07036940408348105,destabilizing
+ZC3H14,CHST12,0.12703741464091658,destabilizing
+ZC3H14,CENPP,0.1167561327039653,destabilizing
+ZC3H14,ARIH1,0.06672268956759514,destabilizing
+ZC3H14,ALK,0.11871455313664732,destabilizing
+ZC3H14,XKR6,0.08906706048186112,destabilizing
+ZC3H14,TCF20,0.08992436574380913,destabilizing
+ZC3H14,EXOC6B,0.09375551360447461,destabilizing
+ZC3H14,DMD,0.08572902205879945,destabilizing
+ZC3H14,SSH2,0.08477938689772571,destabilizing
+ZC3H14,GTF2IRD1,0.059950383408239855,destabilizing
+ZC3H14,RASA2,0.06705422871558665,destabilizing
+ZC3H14,WIPF2,0.07204819175231861,destabilizing
+ZC3H14,SOX5,0.07141728599262201,destabilizing
+ZC3H14,LRRC37A3,0.09179153794229465,destabilizing
+ZC3H14,MLLT3,0.08759109579664744,destabilizing
+ZC3H14,PTPRD,0.07124232441863297,destabilizing
+CNBP,TRERF1,0.2330695709332459,destabilizing
+CNBP,SORCS1,0.13489062579545238,destabilizing
+CNBP,NCOA1,0.08187448315913956,destabilizing
+CNBP,COPA,0.08362617050435153,destabilizing
+CNBP,FCHSD2,0.0931245363971432,destabilizing
+CNBP,PDE3A,0.24038553446076105,destabilizing
+CNBP,UNC79,0.21302325445463138,destabilizing
+CNBP,DOC2B,0.15512520209807001,destabilizing
+CNBP,TMTC2,0.2007284252261391,destabilizing
+CNBP,KALRN,0.14551416925731273,destabilizing
+CNBP,CHD1,0.10630509961763976,destabilizing
+CNBP,PAK3,0.05700001653649185,destabilizing
+CNBP,UBE2E2,0.09904629073489721,destabilizing
+CNBP,PPARD,0.1210797421399581,destabilizing
+CNBP,TOX,0.10979570840219727,destabilizing
+CNBP,BRAF,0.08130002652033318,destabilizing
+CNBP,RYR2,0.23388049247651566,destabilizing
+CNBP,MTMR7,0.23344816534957372,destabilizing
+CNBP,EIF4E,0.1917712828920973,destabilizing
+CNBP,SOX11,0.05511268060442208,destabilizing
+CNBP,EPB41L4B,0.10657172854690049,destabilizing
+CNBP,CACNA1B,0.136209531778789,destabilizing
+CNBP,LRRTM4,0.1286135456440787,destabilizing
+CNBP,SIRPA,0.16356353838670248,destabilizing
+CNBP,PTEN,0.13016337361851663,destabilizing
+CNBP,FRY,0.2494256837735427,destabilizing
+CNBP,MACROD2,0.19820254907341786,destabilizing
+CNBP,FOXN3,0.07704745189531649,destabilizing
+CNBP,SHANK2,0.2694818014910361,destabilizing
+CNBP,CDK12,0.26385969024344763,destabilizing
+CNBP,RFX7,0.21684158243418933,destabilizing
+CNBP,UBR5,0.11142976267476404,destabilizing
+CNBP,JARID2,0.11650699959868227,destabilizing
+CNBP,MPHOSPH8,0.17011044381512805,destabilizing
+CNBP,DIP2C,0.121728196708477,destabilizing
+CNBP,ZNF423,0.07849605235308067,destabilizing
+CNBP,UBR3,0.1475203210214788,destabilizing
+CNBP,MGAT5,0.08214633926892045,destabilizing
+CNBP,DLG2,0.12598705878656222,destabilizing
+CNBP,CHST12,0.28176835217262675,destabilizing
+CNBP,EML5,0.21613028552926564,destabilizing
+CNBP,CENPP,0.24319043191481501,destabilizing
+CNBP,PSME4,0.19677045843288438,destabilizing
+CNBP,TMEM106B,0.18844371150711484,destabilizing
+CNBP,RABGAP1L,0.06030274695056791,destabilizing
+CNBP,EPHA5,0.18025506644186506,destabilizing
+CNBP,KCNB2,0.2099592610017303,destabilizing
+CNBP,ZNF83,0.151493277329472,destabilizing
+CNBP,SOX6,0.13447198339195043,destabilizing
+CNBP,ZNF521,0.16704025419563664,destabilizing
+CNBP,PLEKHA5,0.12717987943459483,destabilizing
+CNBP,NOVA1,0.22294628532669494,destabilizing
+CNBP,CCNY,0.18734901817828728,destabilizing
+CNBP,ARIH1,0.16960102469696783,destabilizing
+CNBP,EPB41L5,0.13499292566543147,destabilizing
+CNBP,GPR158,0.21513619785867286,destabilizing
+CNBP,NCOA2,0.14514909897074163,destabilizing
+CNBP,ALK,0.2228112232910113,destabilizing
+CNBP,ACACA,0.08003405177398412,destabilizing
+CNBP,ARHGAP26,0.08233633083475521,destabilizing
+CNBP,CTNND2,0.0962960213595854,destabilizing
+CNBP,IFT172,0.17331259176911212,destabilizing
+CNBP,CCNT1,0.12681770422137364,destabilizing
+CNBP,DTWD2,0.2631442931757738,destabilizing
+CNBP,SIK3,0.1557158362286727,destabilizing
+CNBP,CPEB3,0.20436899081455345,destabilizing
+CNBP,CADM2,0.09388155034248341,destabilizing
+CNBP,XKR6,0.21446305728894058,destabilizing
+CNBP,CADPS,0.09997184589612852,destabilizing
+CNBP,FGF13,0.0897579777600576,destabilizing
+CNBP,TCF20,0.19949562620773204,destabilizing
+CNBP,CDKAL1,0.08866561978806892,destabilizing
+CNBP,DGKI,0.17110251388610132,destabilizing
+CNBP,EXOC6B,0.22332457041016307,destabilizing
+CNBP,MAGI3,0.18860323554990915,destabilizing
+CNBP,SBF2,0.11236101099845117,destabilizing
+CNBP,INPP4B,0.16056118782270298,destabilizing
+CNBP,ERC1,0.07608005388936538,destabilizing
+CNBP,PTPRS,0.23581652729243918,destabilizing
+CNBP,CBFA2T2,0.1020306603555768,destabilizing
+CNBP,SPDYE3,0.17535926184401904,destabilizing
+CNBP,TMEM178B,0.10792552977107668,destabilizing
+CNBP,KMT2C,0.054100902704718054,destabilizing
+CNBP,DMD,0.2724850532379816,destabilizing
+CNBP,EIF4G3,0.08761291956394476,destabilizing
+CNBP,MCU,0.186165660849652,destabilizing
+CNBP,SSH2,0.16515999994030878,destabilizing
+CNBP,DOCK3,0.2392503795891179,destabilizing
+CNBP,HS6ST3,0.16146960004701771,destabilizing
+CNBP,LPP,0.22682345713922136,destabilizing
+CNBP,STAG1,0.1391813910882292,destabilizing
+CNBP,CAPZA2,0.17374031684044763,destabilizing
+CNBP,ADGRL3,0.06686175348930243,destabilizing
+CNBP,PHACTR1,0.09968180427985858,destabilizing
+CNBP,UBE2R2,0.18742552599439014,destabilizing
+CNBP,GTF2IRD1,0.15167140472842922,destabilizing
+CNBP,CCBE1,0.09029745076376428,destabilizing
+CNBP,FTX,0.061022036965520214,destabilizing
+CNBP,JMJD1C,0.05383515899122704,destabilizing
+CNBP,TTC28,0.14569459019935785,destabilizing
+CNBP,SBNO1,0.08151752054759459,destabilizing
+CNBP,RIMS2,0.10839173596241118,destabilizing
+CNBP,IGF1R,0.0637394180897369,destabilizing
+CNBP,TRIO,0.09562820572203952,destabilizing
+CNBP,KCND2,0.06512228752084631,destabilizing
+CNBP,BTBD9,0.16203947016212542,destabilizing
+CNBP,CNGB1,0.21121497750204574,destabilizing
+CNBP,FMN2,0.146536947344135,destabilizing
+CNBP,ENSG00000228222,0.31093020079477757,destabilizing
+CNBP,ATXN1,0.07580125461296845,destabilizing
+CNBP,SYN3,0.05764701113682366,destabilizing
+CNBP,PRKN,0.18839394390618455,destabilizing
+CNBP,RASA2,0.19631459623769404,destabilizing
+CNBP,PPP1R12B,0.1341068097023488,destabilizing
+CNBP,FRMD4A,0.12141586826229643,destabilizing
+CNBP,CAMK1D,0.08866501020381437,destabilizing
+CNBP,PARD3,0.05554675484338179,destabilizing
+CNBP,SEMA6D,0.178547915108923,destabilizing
+CNBP,WIPF2,0.18631952718537045,destabilizing
+CNBP,DLEU1,0.25669326442476265,destabilizing
+CNBP,TSHZ2,0.10166079309505478,destabilizing
+CNBP,MED13L,0.13479192434973306,destabilizing
+CNBP,KAZN,0.16911191704223538,destabilizing
+CNBP,KANSL1,0.1161983234883238,destabilizing
+CNBP,FRMD5,0.15832578715064866,destabilizing
+CNBP,LINC00174,0.15055036146039258,destabilizing
+CNBP,PPM1E,0.1606085272379591,destabilizing
+CNBP,ARL3,0.12286511801157429,destabilizing
+CNBP,MBD5,0.15859526234962473,destabilizing
+CNBP,ELAVL3,0.1767601757672355,destabilizing
+CNBP,SLIT2,0.23065362831013692,destabilizing
+CNBP,SLC8A1,0.057240091838459364,destabilizing
+CNBP,CLASP1,0.14714144701611948,destabilizing
+CNBP,DOCK4,0.06101521592278068,destabilizing
+CNBP,UNC5C,0.16834372022942357,destabilizing
+CNBP,CACNA2D3,-0.051640891490709176,stabilizing
+CNBP,RC3H1,0.11987174174099177,destabilizing
+CNBP,NEGR1,0.18803939014736315,destabilizing
+CNBP,ENOX1,0.24605253564466179,destabilizing
+CNBP,SCUBE1,0.09510947061727568,destabilizing
+CNBP,GPHN,0.10431442074131418,destabilizing
+CNBP,NAV3,0.20128296606794407,destabilizing
+CNBP,EBF1,0.08565827899879029,destabilizing
+CNBP,TOMM22,0.20404453019455662,destabilizing
+CNBP,MBNL2,0.11143843926572711,destabilizing
+CNBP,ANKFN1,0.07270145400373794,destabilizing
+CNBP,MAGI2,0.07234440262540891,destabilizing
+CNBP,LSAMP,0.11539294668222246,destabilizing
+CNBP,AKAP6,0.18266864524912044,destabilizing
+CNBP,TMED2,0.10165492604454397,destabilizing
+CNBP,ZBTB20,0.1600804343874328,destabilizing
+CNBP,GRIK2,0.1612773717434394,destabilizing
+CNBP,SOX5,0.1226310526990406,destabilizing
+CNBP,LRRC37A3,0.23628428536201104,destabilizing
+CNBP,TMEM132C,0.05752240286544856,destabilizing
+CNBP,EYS,0.1418868693778564,destabilizing
+CNBP,ARID1B,0.1222266256864159,destabilizing
+CNBP,PRKCE,0.12980480849329146,destabilizing
+CNBP,RBFOX1,-0.07676030221300414,stabilizing
+CNBP,SDK1,0.10032667763914768,destabilizing
+CNBP,NRG1,0.08976734957807628,destabilizing
+CNBP,MLLT3,0.2307534636418956,destabilizing
+CNBP,FMN1,0.11689179087780763,destabilizing
+CNBP,ADGRB3,0.120192701007024,destabilizing
+CNBP,ROBO1,0.13923707911210317,destabilizing
+CNBP,SYPL1,0.11117038781720473,destabilizing
+CNBP,PTPRD,0.1415339956673915,destabilizing
+CNBP,FAM155A,0.2071089103640166,destabilizing
+CNBP,LARP1B,0.174894806881681,destabilizing
+PPIG,TRERF1,0.23421325393618553,destabilizing
+PPIG,SORCS1,0.1557291594392897,destabilizing
+PPIG,NCOA1,0.07924863522946156,destabilizing
+PPIG,COPA,0.07112637170992268,destabilizing
+PPIG,FCHSD2,0.11604015364762017,destabilizing
+PPIG,PDE3A,0.21741761410729524,destabilizing
+PPIG,UNC79,0.2506126291264538,destabilizing
+PPIG,DOC2B,0.15731830291154575,destabilizing
+PPIG,TMTC2,0.2289637074717752,destabilizing
+PPIG,KALRN,0.167799078121521,destabilizing
+PPIG,CHD1,0.1313439236999688,destabilizing
+PPIG,PAK3,0.05332328063723589,destabilizing
+PPIG,UBE2E2,0.1033353777683222,destabilizing
+PPIG,PPARD,0.12416032463152152,destabilizing
+PPIG,BRAF,0.06933254468998702,destabilizing
+PPIG,RYR2,0.17030048085207553,destabilizing
+PPIG,MTMR7,0.23889798477100196,destabilizing
+PPIG,EIF4E,0.23584929376914543,destabilizing
+PPIG,SOX11,0.07704641814119338,destabilizing
+PPIG,EPB41L4B,0.14093997313521045,destabilizing
+PPIG,CACNA1B,0.15374776772438128,destabilizing
+PPIG,TBC1D5,0.0561733448342639,destabilizing
+PPIG,LRRTM4,0.15592574904590603,destabilizing
+PPIG,SIRPA,0.22751991455742723,destabilizing
+PPIG,PTEN,0.16230049592006315,destabilizing
+PPIG,FRY,0.2392784668815835,destabilizing
+PPIG,MACROD2,0.21556727311625407,destabilizing
+PPIG,FOXN3,0.059711634731595624,destabilizing
+PPIG,SHANK2,0.31034505322871486,destabilizing
+PPIG,CDK12,0.29576525794796754,destabilizing
+PPIG,RFX7,0.24888100050965786,destabilizing
+PPIG,UBR5,0.10848065391347508,destabilizing
+PPIG,JARID2,0.12361842247021526,destabilizing
+PPIG,MPHOSPH8,0.18099452602148877,destabilizing
+PPIG,DIP2C,0.13878060741857776,destabilizing
+PPIG,ZNF423,0.08305085352491276,destabilizing
+PPIG,UBR3,0.1328362802333177,destabilizing
+PPIG,MGAT5,0.1009107893636596,destabilizing
+PPIG,DLG2,0.13581049355160682,destabilizing
+PPIG,CHST12,0.33409092502630694,destabilizing
+PPIG,EML5,0.24164227598019344,destabilizing
+PPIG,CENPP,0.2496737498558102,destabilizing
+PPIG,PSME4,0.222702234348556,destabilizing
+PPIG,TMEM106B,0.23374168933882747,destabilizing
+PPIG,EPHA5,0.1795695339449547,destabilizing
+PPIG,KCNB2,0.2176851523873518,destabilizing
+PPIG,ZNF83,0.16985442399767545,destabilizing
+PPIG,SOX6,0.12937541415778805,destabilizing
+PPIG,ZNF521,0.19064210024142247,destabilizing
+PPIG,PLEKHA5,0.11901759417553329,destabilizing
+PPIG,NOVA1,0.2106860780935468,destabilizing
+PPIG,CCNY,0.23725032677234595,destabilizing
+PPIG,ARIH1,0.15469991684090956,destabilizing
+PPIG,EPB41L5,0.16386947101576227,destabilizing
+PPIG,GPR158,0.2025314833061863,destabilizing
+PPIG,NCOA2,0.16954888355665618,destabilizing
+PPIG,ALK,0.24205544897596734,destabilizing
+PPIG,ACACA,0.09409172557547871,destabilizing
+PPIG,ARHGAP26,0.05520876418115928,destabilizing
+PPIG,CTNND2,0.08207501757149559,destabilizing
+PPIG,IFT172,0.20839946664228895,destabilizing
+PPIG,CCNT1,0.13031028194027772,destabilizing
+PPIG,DTWD2,0.2996184791447315,destabilizing
+PPIG,SIK3,0.19254945061624698,destabilizing
+PPIG,CPEB3,0.2094511527988063,destabilizing
+PPIG,CADM2,0.09692494121819199,destabilizing
+PPIG,XKR6,0.23616271492301671,destabilizing
+PPIG,RMND5A,0.08428819332337022,destabilizing
+PPIG,CADPS,0.12145777561683496,destabilizing
+PPIG,FGF13,0.07126495818559693,destabilizing
+PPIG,TCF20,0.2216911600341142,destabilizing
+PPIG,CDKAL1,0.1273841084166674,destabilizing
+PPIG,DGKI,0.16538162033195752,destabilizing
+PPIG,EXOC6B,0.2783644678532663,destabilizing
+PPIG,MAGI3,0.21643013602964004,destabilizing
+PPIG,SBF2,0.111859845756935,destabilizing
+PPIG,INPP4B,0.17656572734672968,destabilizing
+PPIG,ERC1,0.07402871266727888,destabilizing
+PPIG,PTPRS,0.2210361202645304,destabilizing
+PPIG,CBFA2T2,0.09719391336358782,destabilizing
+PPIG,SPDYE3,0.1880540466084861,destabilizing
+PPIG,TMEM178B,0.10224658025079417,destabilizing
+PPIG,KMT2C,0.0546993981199207,destabilizing
+PPIG,DMD,0.30722607019922893,destabilizing
+PPIG,EIF4G3,0.06279069889728765,destabilizing
+PPIG,MCU,0.19379866827982678,destabilizing
+PPIG,SSH2,0.18060100656288508,destabilizing
+PPIG,DOCK3,0.2527332693359536,destabilizing
+PPIG,HS6ST3,0.21051383995185297,destabilizing
+PPIG,LPP,0.24731844977178502,destabilizing
+PPIG,STAG1,0.16710004375831455,destabilizing
+PPIG,CAPZA2,0.19412996326170787,destabilizing
+PPIG,ADGRL3,0.08537483649027325,destabilizing
+PPIG,PHACTR1,0.0849163548660841,destabilizing
+PPIG,UBE2R2,0.21354600387116823,destabilizing
+PPIG,GTF2IRD1,0.16971599960879524,destabilizing
+PPIG,CCBE1,0.10411082726736734,destabilizing
+PPIG,FTX,0.0547710873754395,destabilizing
+PPIG,TTC28,0.14825990521499927,destabilizing
+PPIG,SBNO1,0.12186382897960386,destabilizing
+PPIG,RIMS2,0.127818637522835,destabilizing
+PPIG,IGF1R,0.08563395202956459,destabilizing
+PPIG,TRIO,0.10882191530053939,destabilizing
+PPIG,KCND2,0.0624398883020082,destabilizing
+PPIG,BTBD9,0.20278333654844252,destabilizing
+PPIG,CNGB1,0.2301595205436642,destabilizing
+PPIG,FMN2,0.17534837341105125,destabilizing
+PPIG,ENSG00000228222,0.34708148288210044,destabilizing
+PPIG,ATXN1,0.06788192715999013,destabilizing
+PPIG,SYN3,0.05470700757041222,destabilizing
+PPIG,PRKN,0.2652453897933961,destabilizing
+PPIG,RASA2,0.21115458698577044,destabilizing
+PPIG,PPP1R12B,0.14606148779753467,destabilizing
+PPIG,FRMD4A,0.15655785332697805,destabilizing
+PPIG,CAMK1D,0.09061479361956856,destabilizing
+PPIG,PARD3,0.06843814224561975,destabilizing
+PPIG,SEMA6D,0.18008073309965403,destabilizing
+PPIG,WIPF2,0.21233228159780682,destabilizing
+PPIG,DLEU1,0.25877146948897795,destabilizing
+PPIG,TSHZ2,0.12904520998922397,destabilizing
+PPIG,MED13L,0.12214039951966957,destabilizing
+PPIG,AFF3,0.06515585001750031,destabilizing
+PPIG,KAZN,0.176243609196917,destabilizing
+PPIG,KANSL1,0.12228916066301108,destabilizing
+PPIG,FRMD5,0.17383531655636106,destabilizing
+PPIG,LINC00174,0.19551342498800545,destabilizing
+PPIG,PPM1E,0.16551889226478889,destabilizing
+PPIG,ARL3,0.1320266186267437,destabilizing
+PPIG,MBD5,0.15316883073068027,destabilizing
+PPIG,ELAVL3,0.1883830838146014,destabilizing
+PPIG,SLIT2,0.26060087533993775,destabilizing
+PPIG,CLASP1,0.15351589619594605,destabilizing
+PPIG,DOCK4,0.060883646773088766,destabilizing
+PPIG,UNC5C,0.19969096632541192,destabilizing
+PPIG,CACNA2D3,-0.08307923432683706,stabilizing
+PPIG,RC3H1,0.1433466225265522,destabilizing
+PPIG,NEGR1,0.1985680350927041,destabilizing
+PPIG,ENOX1,0.3001031687276077,destabilizing
+PPIG,SCUBE1,0.132490970244361,destabilizing
+PPIG,GPHN,0.1595701474414279,destabilizing
+PPIG,NAV3,0.22579337861736465,destabilizing
+PPIG,EBF1,0.09162553128807703,destabilizing
+PPIG,TOMM22,0.24535750108065085,destabilizing
+PPIG,MBNL2,0.0871276983240801,destabilizing
+PPIG,ANKFN1,0.06702375393877204,destabilizing
+PPIG,MAGI2,0.0934117020205039,destabilizing
+PPIG,LSAMP,0.12478996640065956,destabilizing
+PPIG,AKAP6,0.1977867351081244,destabilizing
+PPIG,TMED2,0.14627576716016513,destabilizing
+PPIG,ZBTB20,0.203461388728156,destabilizing
+PPIG,GRIK2,0.18509606967154027,destabilizing
+PPIG,SOX5,0.1261649239154738,destabilizing
+PPIG,LRRC37A3,0.25650868629078,destabilizing
+PPIG,TMEM132C,0.05592092776582147,destabilizing
+PPIG,EYS,0.15210789902771923,destabilizing
+PPIG,ARID1B,0.12484534719928309,destabilizing
+PPIG,PRKCE,0.130284656107738,destabilizing
+PPIG,RBFOX1,-0.10513757676803191,stabilizing
+PPIG,SDK1,0.1109440604945253,destabilizing
+PPIG,NRG1,0.07122836543243567,destabilizing
+PPIG,MLLT3,0.28273203949078474,destabilizing
+PPIG,FMN1,0.11355580928948061,destabilizing
+PPIG,ADGRB3,0.0838537944605083,destabilizing
+PPIG,ROBO1,0.1881714871262203,destabilizing
+PPIG,SYPL1,0.09199217942916772,destabilizing
+PPIG,PTPRD,0.1727464470132989,destabilizing
+PPIG,FAM155A,0.235029083029089,destabilizing
+PPIG,LARP1B,0.21786504495926917,destabilizing
+AUH,TRERF1,0.11381376597546872,destabilizing
+AUH,SORCS1,0.07207290182059317,destabilizing
+AUH,PDE3A,0.11980080862892836,destabilizing
+AUH,UNC79,0.12246101045386529,destabilizing
+AUH,DOC2B,0.1052072399387271,destabilizing
+AUH,TMTC2,0.09523057560922767,destabilizing
+AUH,KALRN,0.08865092435204347,destabilizing
+AUH,CHD1,0.06155488601042816,destabilizing
+AUH,MTMR7,0.08959125130755467,destabilizing
+AUH,EPB41L4B,0.06933781781941652,destabilizing
+AUH,CACNA1B,0.08138015661169293,destabilizing
+AUH,LRRTM4,0.07956113885276583,destabilizing
+AUH,FRY,0.1008654333134459,destabilizing
+AUH,MACROD2,0.09755794174850747,destabilizing
+AUH,SHANK2,0.13757217915753062,destabilizing
+AUH,CDK12,0.13255394107103974,destabilizing
+AUH,RFX7,0.10624064829494005,destabilizing
+AUH,UBR5,0.07122073805685633,destabilizing
+AUH,MPHOSPH8,0.08346778893726937,destabilizing
+AUH,DIP2C,0.07545032752047685,destabilizing
+AUH,DLG2,0.07956835762313794,destabilizing
+AUH,CHST12,0.17601896062300038,destabilizing
+AUH,EML5,0.147766516784252,destabilizing
+AUH,PSME4,0.08645184936320038,destabilizing
+AUH,TMEM106B,0.0927968350514068,destabilizing
+AUH,EPHA5,0.08709361164514884,destabilizing
+AUH,KCNB2,0.10281389180273194,destabilizing
+AUH,ZNF83,0.1023779682793225,destabilizing
+AUH,ZNF521,0.10026312456458197,destabilizing
+AUH,PLEKHA5,0.06020114086721197,destabilizing
+AUH,NOVA1,0.1313777529900852,destabilizing
+AUH,CCNY,0.10931778133295621,destabilizing
+AUH,ARIH1,0.06973760856163404,destabilizing
+AUH,EPB41L5,0.07641277628427695,destabilizing
+AUH,GPR158,0.10467185126013744,destabilizing
+AUH,NCOA2,0.07819001460182137,destabilizing
+AUH,IFT172,0.0957652904202009,destabilizing
+AUH,SIK3,0.08291704344366466,destabilizing
+AUH,CPEB3,0.09797692629177576,destabilizing
+AUH,XKR6,0.08920649893435954,destabilizing
+AUH,CADPS,0.06841913034823126,destabilizing
+AUH,TCF20,0.11157768927119108,destabilizing
+AUH,EXOC6B,0.12673676431401665,destabilizing
+AUH,MAGI3,0.10526733892028754,destabilizing
+AUH,INPP4B,0.10342441748330906,destabilizing
+AUH,SPDYE3,0.07132079574158692,destabilizing
+AUH,DMD,0.1408998117976255,destabilizing
+AUH,MCU,0.0622823307620299,destabilizing
+AUH,SSH2,0.09008643903732827,destabilizing
+AUH,DOCK3,0.1212872186833663,destabilizing
+AUH,HS6ST3,0.12572743278476414,destabilizing
+AUH,LPP,0.14455568237614558,destabilizing
+AUH,STAG1,0.07133766040696307,destabilizing
+AUH,CAPZA2,0.10741004850515835,destabilizing
+AUH,ADGRL3,0.06385772080456359,destabilizing
+AUH,UBE2R2,0.10412379977120731,destabilizing
+AUH,GTF2IRD1,0.07871998843587737,destabilizing
+AUH,CCBE1,0.05860473088719843,destabilizing
+AUH,TTC28,0.08237752742940542,destabilizing
+AUH,TRIO,0.06217988373794676,destabilizing
+AUH,BTBD9,0.11153723360547463,destabilizing
+AUH,CNGB1,0.11692465641365536,destabilizing
+AUH,FMN2,0.07039502682635741,destabilizing
+AUH,ENSG00000228222,0.12313706643296482,destabilizing
+AUH,PRKN,0.13377733993614427,destabilizing
+AUH,RASA2,0.09379975374338649,destabilizing
+AUH,PPP1R12B,0.06821809158933229,destabilizing
+AUH,FRMD4A,0.07950560875565349,destabilizing
+AUH,SEMA6D,0.06743653617982538,destabilizing
+AUH,WIPF2,0.10264815026854529,destabilizing
+AUH,DLEU1,0.15053264850272727,destabilizing
+AUH,MED13L,0.07547120784526071,destabilizing
+AUH,KAZN,0.08341913590431291,destabilizing
+AUH,FRMD5,0.10174234119602328,destabilizing
+AUH,LINC00174,0.1020050357799726,destabilizing
+AUH,PPM1E,0.08607968028878107,destabilizing
+AUH,MBD5,0.07556063650947617,destabilizing
+AUH,ELAVL3,0.08567304954360801,destabilizing
+AUH,SLIT2,0.15535362618873577,destabilizing
+AUH,UNC5C,0.06751238068097463,destabilizing
+AUH,NEGR1,0.0832153419431811,destabilizing
+AUH,ENOX1,0.11330066576686532,destabilizing
+AUH,NAV3,0.11582213413505249,destabilizing
+AUH,TOMM22,0.1301811593924565,destabilizing
+AUH,LSAMP,0.05531631449382073,destabilizing
+AUH,AKAP6,0.08247582379277249,destabilizing
+AUH,TMED2,0.06486272438295305,destabilizing
+AUH,ZBTB20,0.09003905220325673,destabilizing
+AUH,GRIK2,0.10085709070543444,destabilizing
+AUH,SOX5,0.07480062573156927,destabilizing
+AUH,LRRC37A3,0.11597823098280143,destabilizing
+AUH,EYS,0.07517720045781708,destabilizing
+AUH,PRKCE,0.07988381489636617,destabilizing
+AUH,RBFOX1,-0.06857037840478526,stabilizing
+AUH,MLLT3,0.12127615287655916,destabilizing
+AUH,ADGRB3,0.06679625999865621,destabilizing
+AUH,ROBO1,0.10304528763653986,destabilizing
+AUH,PTPRD,0.07253812752587618,destabilizing
+AUH,FAM155A,0.11026517466464393,destabilizing
+AUH,LARP1B,0.10403416536076246,destabilizing
+SYNCRIP,EIF4E,0.1033754224240055,destabilizing
+SYNCRIP,CDK12,0.10032831107929172,destabilizing
+SYNCRIP,RFX7,0.09721085249361593,destabilizing
+SYNCRIP,MPHOSPH8,0.08646519699090287,destabilizing
+SYNCRIP,KCNB2,0.09267174582476594,destabilizing
+SYNCRIP,CCNT1,0.05412580620211254,destabilizing
+SYNCRIP,XKR6,0.07688385424325468,destabilizing
+SYNCRIP,DMD,0.08534311499001174,destabilizing
+SYNCRIP,MCU,0.07133768765461183,destabilizing
+SYNCRIP,DOCK3,0.0744569567844499,destabilizing
+SYNCRIP,FRMD5,0.0694179915397288,destabilizing
+SYNCRIP,LINC00174,0.06170871235137538,destabilizing
+SYNCRIP,ELAVL3,0.06463101101063014,destabilizing
+SYNCRIP,ENOX1,0.12630508329232445,destabilizing
+SYNCRIP,ZBTB20,0.08679639701464294,destabilizing
+SYNCRIP,MLLT3,0.1018704056611303,destabilizing
+TRNAU1AP,TRERF1,0.17747469576298505,destabilizing
+TRNAU1AP,SORCS1,0.09006817594238828,destabilizing
+TRNAU1AP,FCHSD2,0.06663917025416437,destabilizing
+TRNAU1AP,PDE3A,0.14450432239764985,destabilizing
+TRNAU1AP,UNC79,0.14294533053614183,destabilizing
+TRNAU1AP,DOC2B,0.09405192626603642,destabilizing
+TRNAU1AP,TMTC2,0.12206133217211733,destabilizing
+TRNAU1AP,KALRN,0.11979826879016,destabilizing
+TRNAU1AP,CHD1,0.07903399028105561,destabilizing
+TRNAU1AP,PPARD,0.06745648426953996,destabilizing
+TRNAU1AP,RYR2,0.12987845224505096,destabilizing
+TRNAU1AP,MTMR7,0.1356395545086321,destabilizing
+TRNAU1AP,EIF4E,0.10546567873102584,destabilizing
+TRNAU1AP,SOX11,0.05854419519869482,destabilizing
+TRNAU1AP,EPB41L4B,0.0978233583022297,destabilizing
+TRNAU1AP,CACNA1B,0.0800326939960666,destabilizing
+TRNAU1AP,LRRTM4,0.09852558946471247,destabilizing
+TRNAU1AP,SIRPA,0.10464129773599107,destabilizing
+TRNAU1AP,PTEN,0.09272351633990643,destabilizing
+TRNAU1AP,FRY,0.14498552530058423,destabilizing
+TRNAU1AP,MACROD2,0.12810351361760638,destabilizing
+TRNAU1AP,SHANK2,0.15405150095463294,destabilizing
+TRNAU1AP,CDK12,0.17678720341126697,destabilizing
+TRNAU1AP,RFX7,0.1135027102589059,destabilizing
+TRNAU1AP,UBR5,0.07914482720592837,destabilizing
+TRNAU1AP,JARID2,0.07440654552996119,destabilizing
+TRNAU1AP,MPHOSPH8,0.10629186987272288,destabilizing
+TRNAU1AP,DIP2C,0.10752307517778316,destabilizing
+TRNAU1AP,UBR3,0.09640428177337743,destabilizing
+TRNAU1AP,DLG2,0.0924031460616727,destabilizing
+TRNAU1AP,CHST12,0.1803449926889445,destabilizing
+TRNAU1AP,EML5,0.14496716000199777,destabilizing
+TRNAU1AP,CENPP,0.16886108142094838,destabilizing
+TRNAU1AP,PSME4,0.10039594592689197,destabilizing
+TRNAU1AP,TMEM106B,0.11077471921359633,destabilizing
+TRNAU1AP,EPHA5,0.07233386337264194,destabilizing
+TRNAU1AP,KCNB2,0.13057089308986738,destabilizing
+TRNAU1AP,ZNF83,0.10753670171819601,destabilizing
+TRNAU1AP,SOX6,0.09885759266337428,destabilizing
+TRNAU1AP,ZNF521,0.11272705842429667,destabilizing
+TRNAU1AP,PLEKHA5,0.07850243628333613,destabilizing
+TRNAU1AP,NOVA1,0.1568753828587085,destabilizing
+TRNAU1AP,CCNY,0.11150670311214066,destabilizing
+TRNAU1AP,ARIH1,0.09885985150324082,destabilizing
+TRNAU1AP,FAM171B,0.051339603269793456,destabilizing
+TRNAU1AP,EPB41L5,0.1040816934770572,destabilizing
+TRNAU1AP,GPR158,0.1056126644447438,destabilizing
+TRNAU1AP,NCOA2,0.09329273186169709,destabilizing
+TRNAU1AP,ALK,0.12946691505309552,destabilizing
+TRNAU1AP,ACACA,0.056759707822584576,destabilizing
+TRNAU1AP,CTNND2,0.06696124199169545,destabilizing
+TRNAU1AP,IFT172,0.124125090106572,destabilizing
+TRNAU1AP,CCNT1,0.06212278330352711,destabilizing
+TRNAU1AP,SIK3,0.11682830630093684,destabilizing
+TRNAU1AP,CPEB3,0.12640140413504017,destabilizing
+TRNAU1AP,CADM2,0.061591505209928,destabilizing
+TRNAU1AP,XKR6,0.15384115652274447,destabilizing
+TRNAU1AP,CADPS,0.07408659031403346,destabilizing
+TRNAU1AP,FGF13,0.0689925047187346,destabilizing
+TRNAU1AP,TCF20,0.12024731231840828,destabilizing
+TRNAU1AP,CDKAL1,0.07292684001624254,destabilizing
+TRNAU1AP,DGKI,0.09674846818603439,destabilizing
+TRNAU1AP,EXOC6B,0.144285565328374,destabilizing
+TRNAU1AP,MAGI3,0.12692127657946553,destabilizing
+TRNAU1AP,SBF2,0.08113121899387347,destabilizing
+TRNAU1AP,INPP4B,0.12314757084818988,destabilizing
+TRNAU1AP,PTPRS,0.128741249445784,destabilizing
+TRNAU1AP,CBFA2T2,0.06853986102254453,destabilizing
+TRNAU1AP,SPDYE3,0.0956022033326463,destabilizing
+TRNAU1AP,DMD,0.1777798253757379,destabilizing
+TRNAU1AP,MCU,0.1280237162291846,destabilizing
+TRNAU1AP,SSH2,0.0827390800058691,destabilizing
+TRNAU1AP,DOCK3,0.13046795409070394,destabilizing
+TRNAU1AP,HS6ST3,0.12693876593696116,destabilizing
+TRNAU1AP,LPP,0.1411958178707146,destabilizing
+TRNAU1AP,STAG1,0.07500919796675234,destabilizing
+TRNAU1AP,CAPZA2,0.1046173495563979,destabilizing
+TRNAU1AP,ADGRL3,0.06721237486385184,destabilizing
+TRNAU1AP,UBE2R2,0.12583123417692768,destabilizing
+TRNAU1AP,GTF2IRD1,0.09267238806721043,destabilizing
+TRNAU1AP,CCBE1,0.06737731559230203,destabilizing
+TRNAU1AP,TTC28,0.09226784614091978,destabilizing
+TRNAU1AP,SBNO1,0.062136786627518946,destabilizing
+TRNAU1AP,RIMS2,0.07225800253650104,destabilizing
+TRNAU1AP,IGF1R,0.05960925686738318,destabilizing
+TRNAU1AP,TRIO,0.057371838028210005,destabilizing
+TRNAU1AP,BTBD9,0.11791329158981427,destabilizing
+TRNAU1AP,CNGB1,0.11461061871887795,destabilizing
+TRNAU1AP,FMN2,0.10596611689404187,destabilizing
+TRNAU1AP,ENSG00000228222,0.22069764859776203,destabilizing
+TRNAU1AP,PRKN,0.14399823858604655,destabilizing
+TRNAU1AP,RASA2,0.12066334784031732,destabilizing
+TRNAU1AP,PPP1R12B,0.08945491254804389,destabilizing
+TRNAU1AP,FRMD4A,0.09500689728735517,destabilizing
+TRNAU1AP,CAMK1D,0.06724862939725995,destabilizing
+TRNAU1AP,PARD3,0.05819291016859431,destabilizing
+TRNAU1AP,SEMA6D,0.10627800032606688,destabilizing
+TRNAU1AP,WIPF2,0.12545662884942263,destabilizing
+TRNAU1AP,DLEU1,0.16870160211803273,destabilizing
+TRNAU1AP,TSHZ2,0.06320236897324451,destabilizing
+TRNAU1AP,MED13L,0.0884649162685347,destabilizing
+TRNAU1AP,KAZN,0.10063277556496796,destabilizing
+TRNAU1AP,FRMD5,0.10191669444322178,destabilizing
+TRNAU1AP,LINC00174,0.11772394795262218,destabilizing
+TRNAU1AP,PPM1E,0.12227467514119536,destabilizing
+TRNAU1AP,ARL3,0.07614037409125499,destabilizing
+TRNAU1AP,MBD5,0.0739861614968768,destabilizing
+TRNAU1AP,ELAVL3,0.1008629463939182,destabilizing
+TRNAU1AP,SLIT2,0.14784554856575616,destabilizing
+TRNAU1AP,CLASP1,0.09419129809262947,destabilizing
+TRNAU1AP,UNC5C,0.13721598228158532,destabilizing
+TRNAU1AP,CACNA2D3,-0.052454057893213106,stabilizing
+TRNAU1AP,RC3H1,0.060769236393751334,destabilizing
+TRNAU1AP,NEGR1,0.1064088635386943,destabilizing
+TRNAU1AP,ENOX1,0.14892122043377093,destabilizing
+TRNAU1AP,SCUBE1,0.06048147653782498,destabilizing
+TRNAU1AP,GPHN,0.0918737601636598,destabilizing
+TRNAU1AP,NAV3,0.1227343601238272,destabilizing
+TRNAU1AP,EBF1,0.05745473948983252,destabilizing
+TRNAU1AP,TOMM22,0.1480752632877727,destabilizing
+TRNAU1AP,MAGI2,0.06278173134352999,destabilizing
+TRNAU1AP,LSAMP,0.06675636308053134,destabilizing
+TRNAU1AP,AKAP6,0.0973503904119526,destabilizing
+TRNAU1AP,TMED2,0.0819785459751849,destabilizing
+TRNAU1AP,ZBTB20,0.10708764030851034,destabilizing
+TRNAU1AP,GRIK2,0.11297928244032854,destabilizing
+TRNAU1AP,SOX5,0.06972326971205961,destabilizing
+TRNAU1AP,LRRC37A3,0.1695576125871698,destabilizing
+TRNAU1AP,EYS,0.08624585787279003,destabilizing
+TRNAU1AP,ARID1B,0.07270329776695111,destabilizing
+TRNAU1AP,PRKCE,0.06548973158902151,destabilizing
+TRNAU1AP,RBFOX1,-0.06563640579153039,stabilizing
+TRNAU1AP,SDK1,0.06818942512944767,destabilizing
+TRNAU1AP,NRG1,0.05105620885349743,destabilizing
+TRNAU1AP,MLLT3,0.1486355887863347,destabilizing
+TRNAU1AP,FMN1,0.06323581577089492,destabilizing
+TRNAU1AP,ADGRB3,0.06964014187864494,destabilizing
+TRNAU1AP,ROBO1,0.10741159932472716,destabilizing
+TRNAU1AP,SYPL1,0.06348632805683366,destabilizing
+TRNAU1AP,PTPRD,0.10698200003986837,destabilizing
+TRNAU1AP,FAM155A,0.1457714610598285,destabilizing
+TRNAU1AP,LARP1B,0.13128884696101897,destabilizing
+TNRC6A,MLLT3,0.08949517710031107,destabilizing
+TNRC6B,TRERF1,0.09922641862508713,destabilizing
+TNRC6B,SORCS1,0.08859369150040225,destabilizing
+TNRC6B,PDE3A,0.14975460826914921,destabilizing
+TNRC6B,UNC79,0.11296915629034533,destabilizing
+TNRC6B,DOC2B,0.06641912689413355,destabilizing
+TNRC6B,TMTC2,0.11985072392860997,destabilizing
+TNRC6B,CHD1,0.05479017884181307,destabilizing
+TNRC6B,PPARD,0.061934632864610976,destabilizing
+TNRC6B,MTMR7,0.09605246777069686,destabilizing
+TNRC6B,EPB41L4B,0.06815388975628307,destabilizing
+TNRC6B,CACNA1B,0.07265597753045694,destabilizing
+TNRC6B,LRRTM4,0.06530530159890073,destabilizing
+TNRC6B,PTEN,0.08851462876790987,destabilizing
+TNRC6B,FRY,0.12174834037363215,destabilizing
+TNRC6B,MACROD2,0.08800347362282775,destabilizing
+TNRC6B,SHANK2,0.14574676572859163,destabilizing
+TNRC6B,CDK12,0.1409092999292601,destabilizing
+TNRC6B,RFX7,0.12002254736141918,destabilizing
+TNRC6B,JARID2,0.06416738103049387,destabilizing
+TNRC6B,DIP2C,0.09294473915588708,destabilizing
+TNRC6B,UBR3,0.0883800059418943,destabilizing
+TNRC6B,CHST12,0.14089816598501112,destabilizing
+TNRC6B,EML5,0.1116015269926266,destabilizing
+TNRC6B,PSME4,0.11071221868386266,destabilizing
+TNRC6B,TMEM106B,0.12483316688740795,destabilizing
+TNRC6B,EPHA5,0.0672179235672457,destabilizing
+TNRC6B,KCNB2,0.09228105873490844,destabilizing
+TNRC6B,ZNF83,0.08994021899348471,destabilizing
+TNRC6B,PLEKHA5,0.06707511165293874,destabilizing
+TNRC6B,NOVA1,0.09773203843995913,destabilizing
+TNRC6B,CCNY,0.11434827433024641,destabilizing
+TNRC6B,ARIH1,0.0888643119356516,destabilizing
+TNRC6B,EPB41L5,0.0882392993459097,destabilizing
+TNRC6B,GPR158,0.11184031804087108,destabilizing
+TNRC6B,NCOA2,0.08644089404076133,destabilizing
+TNRC6B,ACACA,0.06957512216452107,destabilizing
+TNRC6B,CTNND2,0.06752500065119653,destabilizing
+TNRC6B,SIK3,0.07604238523442361,destabilizing
+TNRC6B,CPEB3,0.11677709153417225,destabilizing
+TNRC6B,CADM2,0.05849099839945896,destabilizing
+TNRC6B,XKR6,0.09574966716096729,destabilizing
+TNRC6B,TCF20,0.1112283602656933,destabilizing
+TNRC6B,DGKI,0.07628709496923765,destabilizing
+TNRC6B,EXOC6B,0.144189740403598,destabilizing
+TNRC6B,MAGI3,0.08397871251761975,destabilizing
+TNRC6B,PTPRS,0.14035495628457725,destabilizing
+TNRC6B,SPDYE3,0.09414448796044868,destabilizing
+TNRC6B,DMD,0.17353275873908353,destabilizing
+TNRC6B,MCU,0.08858331845975385,destabilizing
+TNRC6B,SSH2,0.08347987006756655,destabilizing
+TNRC6B,DOCK3,0.10453244114833132,destabilizing
+TNRC6B,HS6ST3,0.1077676572824605,destabilizing
+TNRC6B,LPP,0.12339184446300942,destabilizing
+TNRC6B,STAG1,0.09111172779628263,destabilizing
+TNRC6B,CAPZA2,0.08098736761319311,destabilizing
+TNRC6B,UBE2R2,0.10803657360340573,destabilizing
+TNRC6B,GTF2IRD1,0.09970289439611033,destabilizing
+TNRC6B,CCBE1,0.05054329199690637,destabilizing
+TNRC6B,RIMS2,0.057579704126911185,destabilizing
+TNRC6B,BTBD9,0.09167231209903215,destabilizing
+TNRC6B,CNGB1,0.1189601083139558,destabilizing
+TNRC6B,FMN2,0.09251025739340392,destabilizing
+TNRC6B,ENSG00000228222,0.11533013403399352,destabilizing
+TNRC6B,PRKN,0.1275953162329881,destabilizing
+TNRC6B,RASA2,0.09008767801533955,destabilizing
+TNRC6B,FRMD4A,0.07829001723036834,destabilizing
+TNRC6B,DLEU1,0.11524826685539331,destabilizing
+TNRC6B,TSHZ2,0.06183803418956962,destabilizing
+TNRC6B,KAZN,0.07672148342606505,destabilizing
+TNRC6B,LINC00174,0.06738572929905286,destabilizing
+TNRC6B,PPM1E,0.10210226114499002,destabilizing
+TNRC6B,MBD5,0.05991002831884405,destabilizing
+TNRC6B,ELAVL3,0.0754268421243492,destabilizing
+TNRC6B,SLIT2,0.13405461965202534,destabilizing
+TNRC6B,CLASP1,0.07640048193610592,destabilizing
+TNRC6B,UNC5C,0.10738144156008668,destabilizing
+TNRC6B,RC3H1,0.07149400136829917,destabilizing
+TNRC6B,ENOX1,0.13404147994714685,destabilizing
+TNRC6B,GPHN,0.08103893298142505,destabilizing
+TNRC6B,NAV3,0.11001189382008365,destabilizing
+TNRC6B,TOMM22,0.09780968274250705,destabilizing
+TNRC6B,AKAP6,0.07200956670910964,destabilizing
+TNRC6B,ZBTB20,0.09882357669483903,destabilizing
+TNRC6B,GRIK2,0.08175197925610371,destabilizing
+TNRC6B,LRRC37A3,0.1309648154989974,destabilizing
+TNRC6B,EYS,0.06398221053927973,destabilizing
+TNRC6B,ARID1B,0.06372069194016507,destabilizing
+TNRC6B,RBFOX1,-0.050133084610542056,stabilizing
+TNRC6B,MLLT3,0.12724740396457415,destabilizing
+TNRC6B,ROBO1,0.09696438504240935,destabilizing
+TNRC6B,SYPL1,0.06529977358194676,destabilizing
+TNRC6B,PTPRD,0.0621055661942234,destabilizing
+TNRC6B,LARP1B,0.08567031083598414,destabilizing
+TNRC6C,MLLT3,0.08057905562874654,destabilizing
+NXF1,KALRN,0.06347250694815408,destabilizing
+NXF1,MPHOSPH8,0.06792113381445772,destabilizing
+NXF1,CENPP,0.13130558488497718,destabilizing
+NXF1,IFT172,0.07692114075633887,destabilizing
+NXF1,MAGI3,0.0673464585980016,destabilizing
+NXF1,RASA2,0.07027736145207618,destabilizing
+NXF1,LINC00174,0.07388021193189274,destabilizing
+NXF1,ELAVL3,0.06436163959306977,destabilizing
+NXF1,NAV3,0.07845608873638539,destabilizing
+NXF1,MLLT3,0.1016528518249597,destabilizing
+NXF1,LARP1B,0.07412431424591745,destabilizing
+THOC5,TRERF1,0.12038351492677331,destabilizing
+THOC5,SORCS1,0.08240276713805808,destabilizing
+THOC5,COPA,0.06839120750143882,destabilizing
+THOC5,FCHSD2,0.06544227807371995,destabilizing
+THOC5,PDE3A,0.17619282175647238,destabilizing
+THOC5,UNC79,0.15156068234683023,destabilizing
+THOC5,DOC2B,0.09819427473606158,destabilizing
+THOC5,TMTC2,0.1449649565915798,destabilizing
+THOC5,KALRN,0.12587556898559335,destabilizing
+THOC5,CHD1,0.08409089015861898,destabilizing
+THOC5,PAK3,0.05315694670886751,destabilizing
+THOC5,UBE2E2,0.06593515419454193,destabilizing
+THOC5,PPARD,0.06127728783126276,destabilizing
+THOC5,BRAF,0.05153498284681204,destabilizing
+THOC5,RYR2,0.11984470849823342,destabilizing
+THOC5,MTMR7,0.15048118691098603,destabilizing
+THOC5,EIF4E,0.14043674253695798,destabilizing
+THOC5,SOX11,0.06019918957617299,destabilizing
+THOC5,EPB41L4B,0.13026215157670584,destabilizing
+THOC5,CACNA1B,0.07810984546741699,destabilizing
+THOC5,LRRTM4,0.11374232289667048,destabilizing
+THOC5,SIRPA,0.1759349896247269,destabilizing
+THOC5,PTEN,0.08869149997598551,destabilizing
+THOC5,FRY,0.14447743949759353,destabilizing
+THOC5,MACROD2,0.14115833333271638,destabilizing
+THOC5,SHANK2,0.1740171879503035,destabilizing
+THOC5,CDK12,0.17772302373081125,destabilizing
+THOC5,RFX7,0.14765109744922153,destabilizing
+THOC5,UBR5,0.0602218876528924,destabilizing
+THOC5,JARID2,0.07139741926574095,destabilizing
+THOC5,MPHOSPH8,0.09895861107133343,destabilizing
+THOC5,DIP2C,0.10038540758580995,destabilizing
+THOC5,ZNF423,0.06124716874879914,destabilizing
+THOC5,UBR3,0.10764043228200815,destabilizing
+THOC5,MGAT5,0.07621900484491717,destabilizing
+THOC5,DLG2,0.11467706618102104,destabilizing
+THOC5,CHST12,0.22551263333977722,destabilizing
+THOC5,EML5,0.1522785892221351,destabilizing
+THOC5,CENPP,0.12504184875310437,destabilizing
+THOC5,PSME4,0.12178055822490834,destabilizing
+THOC5,TMEM106B,0.1353749839369675,destabilizing
+THOC5,EPHA5,0.11827953730450942,destabilizing
+THOC5,KCNB2,0.115265441544922,destabilizing
+THOC5,ZNF83,0.0998267371532892,destabilizing
+THOC5,SOX6,0.07172570105596146,destabilizing
+THOC5,ZNF521,0.13078582402020317,destabilizing
+THOC5,PLEKHA5,0.1025943036355353,destabilizing
+THOC5,NOVA1,0.14465398850873054,destabilizing
+THOC5,CCNY,0.14268503873179292,destabilizing
+THOC5,ARIH1,0.09724284473917687,destabilizing
+THOC5,FAM171B,0.05424589788910165,destabilizing
+THOC5,EPB41L5,0.10339270706681046,destabilizing
+THOC5,GPR158,0.13465538248082323,destabilizing
+THOC5,NCOA2,0.11545286623107098,destabilizing
+THOC5,MARCKS,0.05350962164337752,destabilizing
+THOC5,ALK,0.11155878729217811,destabilizing
+THOC5,ACACA,0.08434659873014919,destabilizing
+THOC5,IFT172,0.11413905831654168,destabilizing
+THOC5,CCNT1,0.08384972528992889,destabilizing
+THOC5,DTWD2,0.15812155832841868,destabilizing
+THOC5,SIK3,0.08698401968215949,destabilizing
+THOC5,CPEB3,0.16427547874247442,destabilizing
+THOC5,CADM2,0.05683976612428711,destabilizing
+THOC5,XKR6,0.13377713834015487,destabilizing
+THOC5,CADPS,0.0633338378952088,destabilizing
+THOC5,TCF20,0.14629130405494978,destabilizing
+THOC5,CDKAL1,0.06995743014614554,destabilizing
+THOC5,DGKI,0.11491329049936456,destabilizing
+THOC5,EXOC6B,0.1851085680361855,destabilizing
+THOC5,MAGI3,0.11698804340502038,destabilizing
+THOC5,SBF2,0.06784223794670571,destabilizing
+THOC5,INPP4B,0.12727020368742065,destabilizing
+THOC5,PTPRS,0.14276923252732426,destabilizing
+THOC5,CBFA2T2,0.07389297671244278,destabilizing
+THOC5,SPDYE3,0.13169928558063893,destabilizing
+THOC5,TMEM178B,0.06618668629037283,destabilizing
+THOC5,DMD,0.19636888357786525,destabilizing
+THOC5,MCU,0.11899938106081154,destabilizing
+THOC5,SSH2,0.11450006778007826,destabilizing
+THOC5,DOCK3,0.12985870048817041,destabilizing
+THOC5,HS6ST3,0.15218689108989947,destabilizing
+THOC5,LPP,0.16454168138780967,destabilizing
+THOC5,STAG1,0.10149060292052066,destabilizing
+THOC5,CAPZA2,0.11043424599065738,destabilizing
+THOC5,ADGRL3,0.07217499373263338,destabilizing
+THOC5,UBE2R2,0.15010154996683278,destabilizing
+THOC5,GTF2IRD1,0.13718398419807562,destabilizing
+THOC5,CCBE1,0.08959895196602845,destabilizing
+THOC5,TTC28,0.10160341668726465,destabilizing
+THOC5,RIMS2,0.08676521449289148,destabilizing
+THOC5,IGF1R,0.059422354201735084,destabilizing
+THOC5,TRIO,0.07666297387824225,destabilizing
+THOC5,KCND2,0.06700598486302985,destabilizing
+THOC5,BTBD9,0.12300125417558247,destabilizing
+THOC5,CNGB1,0.14969694101004813,destabilizing
+THOC5,FMN2,0.11958850677867693,destabilizing
+THOC5,ENSG00000228222,0.19406495438032198,destabilizing
+THOC5,ATXN1,0.051714322141641,destabilizing
+THOC5,PRKN,0.16529387584615124,destabilizing
+THOC5,RASA2,0.1318639663287931,destabilizing
+THOC5,PPP1R12B,0.08820494926878207,destabilizing
+THOC5,FRMD4A,0.10007790893736068,destabilizing
+THOC5,CAMK1D,0.06201353688487887,destabilizing
+THOC5,SEMA6D,0.10223118528138783,destabilizing
+THOC5,WIPF2,0.13159201313162966,destabilizing
+THOC5,DLEU1,0.18443161230715477,destabilizing
+THOC5,TSHZ2,0.08145627389629222,destabilizing
+THOC5,MED13L,0.06397073916773588,destabilizing
+THOC5,KAZN,0.10347502774867659,destabilizing
+THOC5,KANSL1,0.07461770721403868,destabilizing
+THOC5,FRMD5,0.09197879172526463,destabilizing
+THOC5,LINC00174,0.1117634224301889,destabilizing
+THOC5,PPM1E,0.13128551204711697,destabilizing
+THOC5,ARL3,0.07980650034694792,destabilizing
+THOC5,MBD5,0.11823965583232243,destabilizing
+THOC5,ELAVL3,0.12106220658587133,destabilizing
+THOC5,SLIT2,0.1621650406744619,destabilizing
+THOC5,CLASP1,0.0830541503638773,destabilizing
+THOC5,UNC5C,0.11544806472480855,destabilizing
+THOC5,RC3H1,0.08841809239028009,destabilizing
+THOC5,NEGR1,0.13129342291759052,destabilizing
+THOC5,ENOX1,0.17396650700255586,destabilizing
+THOC5,SCUBE1,0.08228854706870259,destabilizing
+THOC5,GPHN,0.11105560511300319,destabilizing
+THOC5,NAV3,0.1561324432728495,destabilizing
+THOC5,EBF1,0.05462334814306504,destabilizing
+THOC5,TOMM22,0.12318100641606604,destabilizing
+THOC5,MAGI2,0.08936987716049638,destabilizing
+THOC5,LSAMP,0.09619234134491783,destabilizing
+THOC5,AKAP6,0.1222724089533296,destabilizing
+THOC5,TMED2,0.10782274773529595,destabilizing
+THOC5,ZBTB20,0.08307287328387793,destabilizing
+THOC5,GRIK2,0.13094493649483993,destabilizing
+THOC5,SOX5,0.08703700107551908,destabilizing
+THOC5,LRRC37A3,0.16232244833674253,destabilizing
+THOC5,EYS,0.08819727568529853,destabilizing
+THOC5,ARID1B,0.06880815332686047,destabilizing
+THOC5,PRKCE,0.08782154883537578,destabilizing
+THOC5,RBFOX1,-0.06105878389020591,stabilizing
+THOC5,SDK1,0.07753429203393647,destabilizing
+THOC5,NRG1,0.05503729024842751,destabilizing
+THOC5,MLLT3,0.1790064300053162,destabilizing
+THOC5,FMN1,0.07769209340752949,destabilizing
+THOC5,ADGRB3,0.10017924063942638,destabilizing
+THOC5,ROBO1,0.15416193788387714,destabilizing
+THOC5,SYPL1,0.07330645547970963,destabilizing
+THOC5,PTPRD,0.11283758721085511,destabilizing
+THOC5,FAM155A,0.15154347846878494,destabilizing
+THOC5,LARP1B,0.13836174861782424,destabilizing
+SMNDC1,DMD,0.08290016258189586,destabilizing
+SNRPA,TRERF1,0.12773439293142183,destabilizing
+SNRPA,SORCS1,0.07868632217074355,destabilizing
+SNRPA,PDE3A,0.1108440093797601,destabilizing
+SNRPA,UNC79,0.15554524649337886,destabilizing
+SNRPA,DOC2B,0.08168330151291889,destabilizing
+SNRPA,TMTC2,0.12980531164936607,destabilizing
+SNRPA,UBE2E2,0.05914669603872723,destabilizing
+SNRPA,TOX,0.08241392354574324,destabilizing
+SNRPA,RYR2,0.15707222451438663,destabilizing
+SNRPA,MTMR7,0.13568671198048451,destabilizing
+SNRPA,EIF4E,0.13111693913141786,destabilizing
+SNRPA,EPB41L4B,0.060243371172296174,destabilizing
+SNRPA,CACNA1B,0.07299428117472818,destabilizing
+SNRPA,WSB1,0.06465456664776448,destabilizing
+SNRPA,PTEN,0.07348718202737105,destabilizing
+SNRPA,FRY,0.18607336008542874,destabilizing
+SNRPA,RUNX1T1,0.06457729268066893,destabilizing
+SNRPA,MACROD2,0.1059636380399917,destabilizing
+SNRPA,SHANK2,0.10736872250360646,destabilizing
+SNRPA,CDK12,0.1700404272968226,destabilizing
+SNRPA,RFX7,0.12194986156258629,destabilizing
+SNRPA,MPHOSPH8,0.10218063118737401,destabilizing
+SNRPA,ZNF423,0.06131976384042798,destabilizing
+SNRPA,DLG2,0.08094256806371795,destabilizing
+SNRPA,CHST12,0.1791541450681661,destabilizing
+SNRPA,EML5,0.14168561446841402,destabilizing
+SNRPA,CENPP,0.20540832418882232,destabilizing
+SNRPA,PSME4,0.08054410140454837,destabilizing
+SNRPA,TMEM106B,0.10099642375387956,destabilizing
+SNRPA,EPHA5,0.08378290436442058,destabilizing
+SNRPA,KCNB2,0.18226051290237577,destabilizing
+SNRPA,ZNF83,0.07473586159045605,destabilizing
+SNRPA,SOX6,0.09562300674480792,destabilizing
+SNRPA,ZNF521,0.09296065532553952,destabilizing
+SNRPA,PLEKHA5,0.07710901706660098,destabilizing
+SNRPA,NOVA1,0.15177942385779478,destabilizing
+SNRPA,CCNY,0.11111114118404015,destabilizing
+SNRPA,ARIH1,0.07308923387091422,destabilizing
+SNRPA,GPR158,0.12286154705529057,destabilizing
+SNRPA,NCOA2,0.07533015384991112,destabilizing
+SNRPA,ALK,0.19339086599910418,destabilizing
+SNRPA,IFT172,0.11757000557592326,destabilizing
+SNRPA,CCNT1,0.06410406085791454,destabilizing
+SNRPA,DTWD2,0.23174684581944716,destabilizing
+SNRPA,SIK3,0.10980208650590693,destabilizing
+SNRPA,CPEB3,0.1068107843902307,destabilizing
+SNRPA,XKR6,0.1167029862257898,destabilizing
+SNRPA,CADPS,0.0776944307234168,destabilizing
+SNRPA,FGF13,0.07516882983619406,destabilizing
+SNRPA,TCF20,0.08647980768655439,destabilizing
+SNRPA,CDKAL1,0.08780499194988738,destabilizing
+SNRPA,DGKI,0.10611479248762232,destabilizing
+SNRPA,EXOC6B,0.12712082751413809,destabilizing
+SNRPA,MAGI3,0.1226184297412996,destabilizing
+SNRPA,SBF2,0.05934323323222242,destabilizing
+SNRPA,INPP4B,0.07158441932930558,destabilizing
+SNRPA,DMD,0.1451950564222327,destabilizing
+SNRPA,MCU,0.09972445717348766,destabilizing
+SNRPA,SSH2,0.09034013967038287,destabilizing
+SNRPA,DOCK3,0.11560411092571429,destabilizing
+SNRPA,LPP,0.09429725206592816,destabilizing
+SNRPA,STAG1,0.07896803012288481,destabilizing
+SNRPA,CAPZA2,0.12639891431840608,destabilizing
+SNRPA,PHACTR1,0.093528209016097,destabilizing
+SNRPA,RIMS2,0.079442749895609,destabilizing
+SNRPA,BTBD9,0.08146437350449863,destabilizing
+SNRPA,CNGB1,0.129363917116168,destabilizing
+SNRPA,FMN2,0.07561675539759477,destabilizing
+SNRPA,ENSG00000228222,0.1740907681793337,destabilizing
+SNRPA,ATXN1,0.05642560016664205,destabilizing
+SNRPA,SYN3,0.061952327067756004,destabilizing
+SNRPA,PRKN,0.1043079852001751,destabilizing
+SNRPA,RASA2,0.13940880535326983,destabilizing
+SNRPA,PPP1R12B,0.0851076637580959,destabilizing
+SNRPA,FRMD4A,0.0639480911127492,destabilizing
+SNRPA,SEMA6D,0.09274524480341244,destabilizing
+SNRPA,WIPF2,0.11471599856792244,destabilizing
+SNRPA,DLEU1,0.1345012937736065,destabilizing
+SNRPA,TSHZ2,0.06861358329685355,destabilizing
+SNRPA,MED13L,0.06716815151145725,destabilizing
+SNRPA,KAZN,0.08110303369278414,destabilizing
+SNRPA,KANSL1,0.08684202336238023,destabilizing
+SNRPA,FRMD5,0.07397296399862245,destabilizing
+SNRPA,LINC00174,0.12995276327378152,destabilizing
+SNRPA,ARL3,0.08626731280101266,destabilizing
+SNRPA,MBD5,0.09074102607552656,destabilizing
+SNRPA,ELAVL3,0.0888288315696001,destabilizing
+SNRPA,SLIT2,0.09293555770878933,destabilizing
+SNRPA,CLASP1,0.08486007092685706,destabilizing
+SNRPA,UNC5C,0.09893023721269843,destabilizing
+SNRPA,NEGR1,0.10836045922726377,destabilizing
+SNRPA,ENOX1,0.15983547119298525,destabilizing
+SNRPA,NAV3,0.09184583784529153,destabilizing
+SNRPA,TOMM22,0.1382305060356114,destabilizing
+SNRPA,MBNL2,0.056134691602143454,destabilizing
+SNRPA,ANKFN1,0.05430450206505755,destabilizing
+SNRPA,LSAMP,0.05571194921965033,destabilizing
+SNRPA,AKAP6,0.08886825629738067,destabilizing
+SNRPA,TMED2,0.06509913483507272,destabilizing
+SNRPA,ZBTB20,0.13876223618295366,destabilizing
+SNRPA,GRIK2,0.09486955627165165,destabilizing
+SNRPA,SOX5,0.07172339983251817,destabilizing
+SNRPA,LRRC37A3,0.11708021735282373,destabilizing
+SNRPA,EYS,0.07463910188951246,destabilizing
+SNRPA,ARID1B,0.05997556060537009,destabilizing
+SNRPA,PRKCE,0.0663151988841214,destabilizing
+SNRPA,MLLT3,0.17900554151696102,destabilizing
+SNRPA,SYPL1,0.06347940548166962,destabilizing
+SNRPA,PTPRD,0.06683638664997162,destabilizing
+SNRPA,FAM155A,0.13046052516892126,destabilizing
+SNRPA,LARP1B,0.09258158390852897,destabilizing
+G3BP1,TMTC2,0.08448439065921587,destabilizing
+G3BP1,EIF4E,0.10752005554759624,destabilizing
+G3BP1,MACROD2,0.08383916080685758,destabilizing
+G3BP1,CDK12,0.09832664664611374,destabilizing
+G3BP1,CENPP,0.1533857646489899,destabilizing
+G3BP1,KCNB2,0.11423755047206428,destabilizing
+G3BP1,SOX6,0.060560810112937416,destabilizing
+G3BP1,ALK,0.11346989760428641,destabilizing
+G3BP1,CCNT1,0.059683600431453446,destabilizing
+G3BP1,XKR6,0.07138956069092622,destabilizing
+G3BP1,MAGI3,0.07220542035885247,destabilizing
+G3BP1,DMD,0.11525482460353546,destabilizing
+G3BP1,RASA2,0.08563761254928216,destabilizing
+G3BP1,FRMD5,0.07760695212373059,destabilizing
+G3BP1,ELAVL3,0.06420011353215063,destabilizing
+G3BP1,UNC5C,0.07347491872761386,destabilizing
+G3BP1,NEGR1,0.10138419456518566,destabilizing
+G3BP1,LRRC37A3,0.0770706647638719,destabilizing
+G3BP1,MLLT3,0.1102358580566301,destabilizing
+G3BP1,SYPL1,0.052039213379774296,destabilizing
+G3BP2,TRERF1,0.09880469727020261,destabilizing
+G3BP2,SORCS1,0.0820615528618231,destabilizing
+G3BP2,UNC79,0.0947852699382593,destabilizing
+G3BP2,DOC2B,0.0726605307919794,destabilizing
+G3BP2,CHD1,0.07371829521268428,destabilizing
+G3BP2,EPB41L4B,0.08019497585536221,destabilizing
+G3BP2,CACNA1B,0.08799849962685065,destabilizing
+G3BP2,LRRTM4,0.06824831409579821,destabilizing
+G3BP2,FRY,0.09233969547912875,destabilizing
+G3BP2,MACROD2,0.08709268217792426,destabilizing
+G3BP2,SHANK2,0.11964216733912263,destabilizing
+G3BP2,CDK12,0.13058710001654136,destabilizing
+G3BP2,MPHOSPH8,0.09029086284161172,destabilizing
+G3BP2,DLG2,0.06060301359509565,destabilizing
+G3BP2,CHST12,0.16246484068347142,destabilizing
+G3BP2,EML5,0.11675285154062552,destabilizing
+G3BP2,PSME4,0.11369066770501844,destabilizing
+G3BP2,TMEM106B,0.11048434217375326,destabilizing
+G3BP2,ZNF83,0.0932451874796632,destabilizing
+G3BP2,SOX6,0.06044808880562346,destabilizing
+G3BP2,NOVA1,0.12921253744106045,destabilizing
+G3BP2,CCNY,0.09969453414008629,destabilizing
+G3BP2,ALK,0.11155579007228644,destabilizing
+G3BP2,IFT172,0.09537969712281898,destabilizing
+G3BP2,CADM2,0.06589909927417999,destabilizing
+G3BP2,XKR6,0.10428260032649138,destabilizing
+G3BP2,TCF20,0.08736809713031804,destabilizing
+G3BP2,CDKAL1,0.07771292259947409,destabilizing
+G3BP2,DGKI,0.07012475285680468,destabilizing
+G3BP2,EXOC6B,0.08843929206967464,destabilizing
+G3BP2,MAGI3,0.08776346810053728,destabilizing
+G3BP2,SBF2,0.06536778577738117,destabilizing
+G3BP2,INPP4B,0.08895116039348622,destabilizing
+G3BP2,DMD,0.15247529870663307,destabilizing
+G3BP2,SSH2,0.06475214867617453,destabilizing
+G3BP2,DOCK3,0.11933477276401702,destabilizing
+G3BP2,HS6ST3,0.10290787293333896,destabilizing
+G3BP2,LPP,0.10457565207518321,destabilizing
+G3BP2,STAG1,0.08976394704653165,destabilizing
+G3BP2,CAPZA2,0.06829650218335183,destabilizing
+G3BP2,UBE2R2,0.09481206585485187,destabilizing
+G3BP2,GTF2IRD1,0.06488790106773548,destabilizing
+G3BP2,BTBD9,0.08670278224816992,destabilizing
+G3BP2,CNGB1,0.11728695473318354,destabilizing
+G3BP2,FMN2,0.06569615449946654,destabilizing
+G3BP2,ENSG00000228222,0.11549130604984889,destabilizing
+G3BP2,PRKN,0.11344892708741243,destabilizing
+G3BP2,RASA2,0.09531552136107653,destabilizing
+G3BP2,FRMD4A,0.0708863813041096,destabilizing
+G3BP2,SEMA6D,0.08114391489949732,destabilizing
+G3BP2,WIPF2,0.09482954276121354,destabilizing
+G3BP2,DLEU1,0.11807095234348307,destabilizing
+G3BP2,TSHZ2,0.06323954287837939,destabilizing
+G3BP2,FRMD5,0.08895965162931746,destabilizing
+G3BP2,LINC00174,0.08919298031958099,destabilizing
+G3BP2,PPM1E,0.0893064042377258,destabilizing
+G3BP2,MBD5,0.07441308237144109,destabilizing
+G3BP2,ELAVL3,0.09564028054728702,destabilizing
+G3BP2,SLIT2,0.12557869199579252,destabilizing
+G3BP2,NEGR1,0.08943296634579509,destabilizing
+G3BP2,ENOX1,0.1205690373980286,destabilizing
+G3BP2,GPHN,0.06687138772149137,destabilizing
+G3BP2,NAV3,0.08659585979033653,destabilizing
+G3BP2,TOMM22,0.12113269095246518,destabilizing
+G3BP2,LSAMP,0.06656540220698812,destabilizing
+G3BP2,AKAP6,0.07965344403270265,destabilizing
+G3BP2,TMED2,0.07734818681707838,destabilizing
+G3BP2,ZBTB20,0.07889874292146493,destabilizing
+G3BP2,GRIK2,0.09164775511861717,destabilizing
+G3BP2,LRRC37A3,0.1305903454355005,destabilizing
+G3BP2,EYS,0.05802949190041661,destabilizing
+G3BP2,ARID1B,0.0670607254402868,destabilizing
+G3BP2,RBFOX1,-0.051863111412312944,stabilizing
+G3BP2,MLLT3,0.13551412002314733,destabilizing
+G3BP2,ADGRB3,0.06959818764041345,destabilizing
+G3BP2,ROBO1,0.09086950698954196,destabilizing
+G3BP2,PTPRD,0.07475299397257547,destabilizing
+G3BP2,FAM155A,0.10176516056862926,destabilizing
+G3BP2,LARP1B,0.07475419023528437,destabilizing
+PRKRA,TRERF1,0.1428399320008667,destabilizing
+PRKRA,SORCS1,0.07129911426558534,destabilizing
+PRKRA,NCOA1,0.05792078927619991,destabilizing
+PRKRA,COPA,0.05816870091507331,destabilizing
+PRKRA,PDE3A,0.1390054642418781,destabilizing
+PRKRA,UNC79,0.12856196321880212,destabilizing
+PRKRA,DOC2B,0.0937493530707188,destabilizing
+PRKRA,TMTC2,0.10728767486034835,destabilizing
+PRKRA,KALRN,0.07701836097497164,destabilizing
+PRKRA,CHD1,0.07850342957282766,destabilizing
+PRKRA,UBE2E2,0.059900943503250405,destabilizing
+PRKRA,PPARD,0.08144553869641809,destabilizing
+PRKRA,RYR2,0.12038189814222552,destabilizing
+PRKRA,MTMR7,0.15535195399730745,destabilizing
+PRKRA,EPB41L4B,0.08542797569559477,destabilizing
+PRKRA,CACNA1B,0.08939275770816053,destabilizing
+PRKRA,LRRTM4,0.06755558660641402,destabilizing
+PRKRA,FRY,0.15125901744413334,destabilizing
+PRKRA,MACROD2,0.11382851223958179,destabilizing
+PRKRA,SHANK2,0.1629765417634063,destabilizing
+PRKRA,CDK12,0.17160367578153096,destabilizing
+PRKRA,RFX7,0.10333575793736505,destabilizing
+PRKRA,MPHOSPH8,0.10086285246472862,destabilizing
+PRKRA,DIP2C,0.10228004686257221,destabilizing
+PRKRA,UBR3,0.07436737586406415,destabilizing
+PRKRA,DLG2,0.08760544931191538,destabilizing
+PRKRA,CHST12,0.21113025773095978,destabilizing
+PRKRA,EML5,0.11497663680907716,destabilizing
+PRKRA,CENPP,0.186470704314149,destabilizing
+PRKRA,PSME4,0.12218342212081598,destabilizing
+PRKRA,TMEM106B,0.11604445427456989,destabilizing
+PRKRA,EPHA5,0.08550258363027584,destabilizing
+PRKRA,KCNB2,0.15586068746460574,destabilizing
+PRKRA,ZNF83,0.09286882103066206,destabilizing
+PRKRA,SOX6,0.10044163803003717,destabilizing
+PRKRA,ZNF521,0.10183359910259573,destabilizing
+PRKRA,PLEKHA5,0.08114184758777304,destabilizing
+PRKRA,NOVA1,0.14290497652815437,destabilizing
+PRKRA,CCNY,0.11594718430379282,destabilizing
+PRKRA,ARIH1,0.11960545318782398,destabilizing
+PRKRA,EPB41L5,0.08075288510969325,destabilizing
+PRKRA,GPR158,0.11517276705698315,destabilizing
+PRKRA,NCOA2,0.09131839141987025,destabilizing
+PRKRA,ALK,0.10540857270886027,destabilizing
+PRKRA,IFT172,0.1210512632504714,destabilizing
+PRKRA,CCNT1,0.07981215187081236,destabilizing
+PRKRA,DTWD2,0.1850743736917743,destabilizing
+PRKRA,SIK3,0.11613233257150601,destabilizing
+PRKRA,CPEB3,0.14480772522221885,destabilizing
+PRKRA,CADM2,0.05949958286679086,destabilizing
+PRKRA,XKR6,0.11035601999203262,destabilizing
+PRKRA,TCF20,0.0874867291213015,destabilizing
+PRKRA,DGKI,0.09037180343027047,destabilizing
+PRKRA,EXOC6B,0.1496173332745234,destabilizing
+PRKRA,MAGI3,0.1254880232085282,destabilizing
+PRKRA,SBF2,0.0663372315929845,destabilizing
+PRKRA,INPP4B,0.10319573646625887,destabilizing
+PRKRA,CBFA2T2,0.07347702841729434,destabilizing
+PRKRA,SPDYE3,0.11225899941988782,destabilizing
+PRKRA,DMD,0.16760244652157275,destabilizing
+PRKRA,EIF4G3,0.05796158604556927,destabilizing
+PRKRA,MCU,0.07900791709018695,destabilizing
+PRKRA,SSH2,0.08404200623683687,destabilizing
+PRKRA,DOCK3,0.13649449396195334,destabilizing
+PRKRA,HS6ST3,0.11840956720941063,destabilizing
+PRKRA,LPP,0.13673959099736263,destabilizing
+PRKRA,STAG1,0.09756946510545572,destabilizing
+PRKRA,CAPZA2,0.10123309573311812,destabilizing
+PRKRA,UBE2R2,0.09408538958146845,destabilizing
+PRKRA,GTF2IRD1,0.0982204863011929,destabilizing
+PRKRA,SBNO1,0.06708197331851273,destabilizing
+PRKRA,RIMS2,0.0889044514480288,destabilizing
+PRKRA,BTBD9,0.10715592147045173,destabilizing
+PRKRA,CNGB1,0.12173426357038794,destabilizing
+PRKRA,FMN2,0.09267270925626359,destabilizing
+PRKRA,ENSG00000228222,0.1856307996618266,destabilizing
+PRKRA,PRKN,0.12870214593398677,destabilizing
+PRKRA,RASA2,0.12574999579743631,destabilizing
+PRKRA,PPP1R12B,0.07368328970515105,destabilizing
+PRKRA,FRMD4A,0.10422412806382145,destabilizing
+PRKRA,CAMK1D,0.06278740104165095,destabilizing
+PRKRA,SEMA6D,0.11617588840235703,destabilizing
+PRKRA,WIPF2,0.11436528165821612,destabilizing
+PRKRA,DLEU1,0.15222659860752435,destabilizing
+PRKRA,TSHZ2,0.07066278835073546,destabilizing
+PRKRA,MED13L,0.07142335246608777,destabilizing
+PRKRA,KAZN,0.09608964826864141,destabilizing
+PRKRA,KANSL1,0.0645195822237056,destabilizing
+PRKRA,FRMD5,0.06833031286236978,destabilizing
+PRKRA,LINC00174,0.10623245822217033,destabilizing
+PRKRA,PPM1E,0.092920934721438,destabilizing
+PRKRA,ARL3,0.08431795379399563,destabilizing
+PRKRA,MBD5,0.09238064152699245,destabilizing
+PRKRA,ELAVL3,0.11022475371889569,destabilizing
+PRKRA,SLIT2,0.1296180913911479,destabilizing
+PRKRA,CLASP1,0.09940606472940218,destabilizing
+PRKRA,UNC5C,0.09245393778217204,destabilizing
+PRKRA,RC3H1,0.08353359264600248,destabilizing
+PRKRA,NEGR1,0.10308442301648828,destabilizing
+PRKRA,ENOX1,0.14274344337944486,destabilizing
+PRKRA,SCUBE1,0.0775668942768454,destabilizing
+PRKRA,GPHN,0.0855760661298192,destabilizing
+PRKRA,NAV3,0.12265793756478148,destabilizing
+PRKRA,TOMM22,0.12583779471488274,destabilizing
+PRKRA,MBNL2,0.05806057368708686,destabilizing
+PRKRA,MAGI2,0.05319018983544368,destabilizing
+PRKRA,LSAMP,0.056584922053023026,destabilizing
+PRKRA,AKAP6,0.11369680581893249,destabilizing
+PRKRA,TMED2,0.08945690522119308,destabilizing
+PRKRA,ZBTB20,0.10766865537564027,destabilizing
+PRKRA,GRIK2,0.10799609729660332,destabilizing
+PRKRA,SOX5,0.08343314495027639,destabilizing
+PRKRA,LRRC37A3,0.14957920811304162,destabilizing
+PRKRA,EYS,0.08331603176903578,destabilizing
+PRKRA,PRKCE,0.09517748698488841,destabilizing
+PRKRA,RBFOX1,-0.06526074870493202,stabilizing
+PRKRA,NRG1,0.06300950417069008,destabilizing
+PRKRA,MLLT3,0.17013581876764508,destabilizing
+PRKRA,FMN1,0.05543389262511254,destabilizing
+PRKRA,ROBO1,0.10331690606425435,destabilizing
+PRKRA,SYPL1,0.09781434803664932,destabilizing
+PRKRA,PTPRD,0.10036166772551944,destabilizing
+PRKRA,FAM155A,0.13728111790750117,destabilizing
+PRKRA,LARP1B,0.09140269172676918,destabilizing
diff --git a/output/tier3/results/neuroblastoma_network_corrected.csv b/output/tier3/results/neuroblastoma_network_corrected.csv
new file mode 100644
index 0000000000000000000000000000000000000000..d54f38ebe199a9b4291b35a13bf9e9959f4a3504
--- /dev/null
+++ b/output/tier3/results/neuroblastoma_network_corrected.csv
@@ -0,0 +1,327 @@
+rbp,target,spearman_r,direction
+ELAVL3,ELAVL3,-0.09901721378074843,stabilizing
+HNRNPA2B1,TRERF1,-0.0771480542877827,stabilizing
+HNRNPA2B1,SORCS1,-0.051554621567045954,stabilizing
+HNRNPA2B1,EYA4,0.08184442111733606,destabilizing
+HNRNPA2B1,EPB41L4B,-0.10684724719818821,stabilizing
+HNRNPA2B1,LRRTM4,-0.173787347432368,stabilizing
+HNRNPA2B1,MAP4K3,-0.05156459416485649,stabilizing
+HNRNPA2B1,RUNX1T1,0.055784642701739634,destabilizing
+HNRNPA2B1,JARID2,-0.05069598777681137,stabilizing
+HNRNPA2B1,ZNF423,-0.05655313942122734,stabilizing
+HNRNPA2B1,MGAT5,-0.10069184706966657,stabilizing
+HNRNPA2B1,CENPP,0.08848601997250133,destabilizing
+HNRNPA2B1,KCNB2,0.05333640496574631,destabilizing
+HNRNPA2B1,SOX6,-0.053133677882471,stabilizing
+HNRNPA2B1,DTL,0.18685095472909544,destabilizing
+HNRNPA2B1,EPB41L5,-0.07840888595567758,stabilizing
+HNRNPA2B1,GPR158,-0.0848367931404853,stabilizing
+HNRNPA2B1,PRKCB,-0.0542582194331089,stabilizing
+HNRNPA2B1,PUM2,-0.0688821747975449,stabilizing
+HNRNPA2B1,ALK,0.12874406573133312,destabilizing
+HNRNPA2B1,CTNND2,-0.0605222467689271,stabilizing
+HNRNPA2B1,SBF2,-0.05966002147161108,stabilizing
+HNRNPA2B1,INPP4B,-0.13193089896323235,stabilizing
+HNRNPA2B1,ERC1,-0.08725920480415651,stabilizing
+HNRNPA2B1,CBFA2T2,-0.056597699153421645,stabilizing
+HNRNPA2B1,TCF12,-0.07181643211622032,stabilizing
+HNRNPA2B1,DOCK3,-0.050942797439652944,stabilizing
+HNRNPA2B1,HS6ST3,-0.07690268333114358,stabilizing
+HNRNPA2B1,LPP,-0.05710254854240716,stabilizing
+HNRNPA2B1,CAPZA2,-0.04996443747398852,stabilizing
+HNRNPA2B1,CCBE1,-0.10242228872207959,stabilizing
+HNRNPA2B1,FTX,-0.05233280251709954,stabilizing
+HNRNPA2B1,TRIO,-0.0717571450266729,stabilizing
+HNRNPA2B1,CNGB1,-0.07530026555126029,stabilizing
+HNRNPA2B1,FRMD4A,-0.06131390138327187,stabilizing
+HNRNPA2B1,DOCK4,-0.058102685545594834,stabilizing
+HNRNPA2B1,SCUBE1,-0.09436265999452541,stabilizing
+HNRNPA2B1,GPHN,-0.0537829095731789,stabilizing
+HNRNPA2B1,NAV3,-0.06812650524288551,stabilizing
+HNRNPA2B1,MAGI2,-0.06068767775471253,stabilizing
+HNRNPA2B1,LRRC37A3,-0.0629687498676934,stabilizing
+HNRNPA2B1,PRKCE,-0.07365294384568755,stabilizing
+HNRNPA2B1,RORA,0.05197362847300789,destabilizing
+HNRNPA2B1,ADGRB3,-0.05587694211011875,stabilizing
+HNRNPA2B1,ROBO1,-0.05106493730066615,stabilizing
+HNRNPA2B1,FAM155A,-0.05800540438836861,stabilizing
+HNRNPA2B1,LARP1B,-0.05343903212451697,stabilizing
+HNRNPC,LRRTM4,-0.050341539826690866,stabilizing
+HNRNPC,DTL,0.06967280280519016,destabilizing
+HNRNPC,INPP4B,-0.054607660488301304,stabilizing
+HNRNPD,EYA4,0.050925086111213984,destabilizing
+HNRNPD,EPB41L4B,-0.06339430428575081,stabilizing
+HNRNPD,LRRTM4,-0.10727351561294228,stabilizing
+HNRNPD,MGAT5,-0.06956996636926448,stabilizing
+HNRNPD,CENPP,0.0872012507525083,destabilizing
+HNRNPD,DTL,0.10164602517567424,destabilizing
+HNRNPD,ALK,0.076459869414079,destabilizing
+HNRNPD,ENAH,-0.0498416101291403,stabilizing
+HNRNPD,INPP4B,-0.09121868598207714,stabilizing
+HNRNPD,ERC1,-0.05172320998172095,stabilizing
+HNRNPD,TCF12,-0.052195791239408394,stabilizing
+HNRNPD,CCBE1,-0.07658821377733434,stabilizing
+HNRNPD,FRMD4A,-0.05297783053653505,stabilizing
+HNRNPD,SEMA6D,-0.06317094879557811,stabilizing
+HNRNPD,SLC8A1,-0.05640418336292164,stabilizing
+HNRNPD,SCUBE1,-0.06397021245323296,stabilizing
+HNRNPD,PRKCE,-0.054519001354056386,stabilizing
+HNRNPD,AUTS2,-0.05100784720233969,stabilizing
+HNRNPF,LRRTM4,-0.055579938393030076,stabilizing
+HNRNPF,DTL,0.05745450530041685,destabilizing
+HNRNPF,INPP4B,-0.05083546798969305,stabilizing
+HNRNPH1,EPB41L5,-0.0522974306213901,stabilizing
+HNRNPK,EPB41L4B,-0.0634187022423857,stabilizing
+HNRNPK,LRRTM4,-0.11507460436564679,stabilizing
+HNRNPK,ZNF423,-0.0551493269922192,stabilizing
+HNRNPK,MGAT5,-0.07175962562503349,stabilizing
+HNRNPK,DTL,0.11098458787478638,destabilizing
+HNRNPK,MARCKS,0.07130839537349229,destabilizing
+HNRNPK,ALK,0.0666795119134857,destabilizing
+HNRNPK,INPP4B,-0.06702886806580188,stabilizing
+HNRNPK,DMD,0.04939631362354211,destabilizing
+HNRNPK,CCBE1,-0.07839466522498564,stabilizing
+HNRNPK,FRMD4A,-0.0537411312626738,stabilizing
+HNRNPK,DOCK4,-0.05345893274017692,stabilizing
+HNRNPK,NAV3,-0.062089465229822116,stabilizing
+HNRNPK,ADGRB3,-0.05139280938503599,stabilizing
+HNRNPM,EPB41L4B,-0.060584398875041634,stabilizing
+HNRNPM,LRRTM4,-0.05613531485745984,stabilizing
+HNRNPM,DTL,0.08994617910397337,destabilizing
+HNRNPM,INPP4B,-0.058118428749900315,stabilizing
+HNRNPM,CCBE1,-0.05936081645706214,stabilizing
+HNRNPM,SCUBE1,-0.056231361886666865,stabilizing
+HNRNPU,EYA4,0.05591361580001804,destabilizing
+HNRNPU,EPB41L4B,-0.07703350896545742,stabilizing
+HNRNPU,LRRTM4,-0.06342282354165045,stabilizing
+HNRNPU,MGAT5,-0.08345435861803939,stabilizing
+HNRNPU,CENPP,0.06827370366200591,destabilizing
+HNRNPU,SOX6,-0.05738238242608719,stabilizing
+HNRNPU,DTL,0.08945026142478747,destabilizing
+HNRNPU,EPB41L5,-0.06499029537620714,stabilizing
+HNRNPU,PRKCB,-0.05350527659177866,stabilizing
+HNRNPU,PUM2,-0.04966137880477919,stabilizing
+HNRNPU,ALK,0.07776554585912246,destabilizing
+HNRNPU,INPP4B,-0.07224363095577525,stabilizing
+HNRNPU,ERC1,-0.05962764983448764,stabilizing
+HNRNPU,TCF12,-0.05025143427954706,stabilizing
+HNRNPU,CCBE1,-0.08752694245235397,stabilizing
+HNRNPU,CAMK1D,0.05109637034472685,destabilizing
+HNRNPU,SLC8A1,-0.06489400078587315,stabilizing
+HNRNPU,SCUBE1,-0.0759349957564829,stabilizing
+RBFOX1,TMEM106B,0.053570512991136396,destabilizing
+RBFOX1,RBFOX1,-0.3663445133445474,stabilizing
+RBFOX2,DTL,-0.05880924759581422,stabilizing
+RBFOX2,INPP4B,0.06129401162754896,destabilizing
+RBFOX2,SCUBE1,0.05448460771443076,destabilizing
+RBFOX2,RBFOX1,-0.050189308063837805,stabilizing
+RBM39,CCBE1,-0.04992184338094396,stabilizing
+RBM39,EBF1,-0.051939595719099015,stabilizing
+SRSF3,EPB41L4B,-0.05832914875817493,stabilizing
+SRSF3,LRRTM4,-0.0737830602199292,stabilizing
+SRSF3,ZNF423,-0.05178197958368779,stabilizing
+SRSF3,MGAT5,-0.07269030097678464,stabilizing
+SRSF3,CENPP,0.06476054550521436,destabilizing
+SRSF3,DTL,0.11328447057571343,destabilizing
+SRSF3,ALK,0.07105792914316456,destabilizing
+SRSF3,INPP4B,-0.09274396821554562,stabilizing
+SRSF3,CCBE1,-0.05530645367894546,stabilizing
+SRSF3,SCUBE1,-0.05303853710847345,stabilizing
+SRSF3,PRKCE,-0.05638285673294065,stabilizing
+SRSF4,MGAT5,-0.06263224977347574,stabilizing
+SRSF4,CCBE1,-0.04976621012229455,stabilizing
+SRSF7,EPB41L4B,-0.051425811250291144,stabilizing
+SRSF7,LRRTM4,-0.09551313132839331,stabilizing
+SRSF7,CENPP,0.06127034801946727,destabilizing
+SRSF7,DTL,0.09099381262836462,destabilizing
+SRSF7,ALK,0.06858463262878835,destabilizing
+SRSF7,INPP4B,-0.07300021193710053,stabilizing
+SRSF7,TCF12,-0.06634320161895499,stabilizing
+SRSF7,CCBE1,-0.07791107013004939,stabilizing
+SRSF7,SLC8A1,-0.055132060902511625,stabilizing
+SRSF7,PRKCE,-0.05338453093973749,stabilizing
+SRSF9,LRRTM4,-0.06354931813494792,stabilizing
+SRSF9,CENPP,0.05834425471790942,destabilizing
+SRSF9,DTL,0.07359329860503926,destabilizing
+SRSF9,ALK,0.058547863327160506,destabilizing
+SRSF10,EPB41L4B,-0.051576867613321815,stabilizing
+SRSF10,LRRTM4,-0.07505860481241701,stabilizing
+SRSF10,MGAT5,-0.055468698308589304,stabilizing
+SRSF10,DTL,0.05538331332305486,destabilizing
+SRSF10,CCBE1,-0.05679603105129404,stabilizing
+TRA2B,TBC1D5,-0.05045534082815718,stabilizing
+TRA2B,LRRTM4,-0.05650640869768618,stabilizing
+TRA2B,DTL,0.05398557980364423,destabilizing
+TRA2B,ALK,0.0500583205615828,destabilizing
+TRA2B,INPP4B,-0.07002359638366787,stabilizing
+TRA2B,CCBE1,-0.06261737461450573,stabilizing
+PTBP1,EPB41L4B,-0.05670057540486608,stabilizing
+PTBP1,LRRTM4,-0.05581269849505017,stabilizing
+PTBP1,DTL,0.0631617986950004,destabilizing
+PTBP1,INPP4B,-0.052385736720733295,stabilizing
+PTBP1,FRMD4A,-0.05122397003477078,stabilizing
+PTBP1,SCUBE1,-0.06211536846924363,stabilizing
+PCBP2,MARCKS,-0.05168922807262529,stabilizing
+MBNL2,MBNL2,-0.3008520725795035,stabilizing
+QKI,MGAT5,-0.05508054329168699,stabilizing
+QKI,DTL,0.05726135212484754,destabilizing
+QKI,PUM2,-0.05108152461792444,stabilizing
+QKI,INPP4B,-0.05512163753032811,stabilizing
+QKI,SCUBE1,-0.057214018162460654,stabilizing
+QKI,AUTS2,-0.05209101598585098,stabilizing
+KHDRBS1,ALK,0.04939797331373624,destabilizing
+CPEB3,CPEB3,0.10747726696065503,destabilizing
+PUM2,MGAT5,-0.05064067222218434,stabilizing
+PUM2,DTL,0.049336252320760686,destabilizing
+PUM2,PUM2,-0.3256491587734809,stabilizing
+PUM2,PARD3,-0.049628876986649306,stabilizing
+CNOT1,SYN3,0.05143325138236062,destabilizing
+PABPC1,PAK3,0.05020296836920947,destabilizing
+PABPC1,EPB41L4B,0.09241595522142661,destabilizing
+PABPC1,LRRTM4,0.11618379735204848,destabilizing
+PABPC1,MACROD2,0.054756789968988834,destabilizing
+PABPC1,ZNF423,0.06649804639100586,destabilizing
+PABPC1,MGAT5,0.08627614375786392,destabilizing
+PABPC1,CENPP,-0.0684230968125493,stabilizing
+PABPC1,EPHA5,0.049981301473129826,destabilizing
+PABPC1,DTL,-0.12215969017689482,stabilizing
+PABPC1,GPR158,0.05273002324191193,destabilizing
+PABPC1,PUM2,0.06424634903563693,destabilizing
+PABPC1,ALK,-0.0978184163270902,stabilizing
+PABPC1,INPP4B,0.10936625026381838,destabilizing
+PABPC1,ERC1,0.06563593679638727,destabilizing
+PABPC1,TCF12,0.05619298728696066,destabilizing
+PABPC1,DOCK3,0.05385421525335664,destabilizing
+PABPC1,HS6ST3,0.0528764136743371,destabilizing
+PABPC1,CCBE1,0.09477604381726613,destabilizing
+PABPC1,FTX,0.06781786241560922,destabilizing
+PABPC1,PARD3,0.06178927767418053,destabilizing
+PABPC1,DOCK4,0.07016545208512291,destabilizing
+PABPC1,SCUBE1,0.04937846233958659,destabilizing
+PABPC1,NAV3,0.06834691841456243,destabilizing
+PABPC1,KCNQ5,0.056451583300952166,destabilizing
+PABPC1,ZBTB20,0.0508378900354576,destabilizing
+PABPC1,LRRC37A3,0.07559189157418932,destabilizing
+PABPC1,PRKCE,0.05462332584542376,destabilizing
+PABPC1,AUTS2,0.05035894006417495,destabilizing
+CPSF1,DTL,0.0521428786197467,destabilizing
+CSTF3,MGAT5,-0.05125441021586908,stabilizing
+CSTF3,CCBE1,-0.04964563014485369,stabilizing
+NUDT21,CENPP,0.05187553097780452,destabilizing
+NUDT21,ALK,0.05116674958655413,destabilizing
+EWSR1,EPB41L4B,-0.05454553659818139,stabilizing
+EWSR1,LRRTM4,-0.0663611750314705,stabilizing
+EWSR1,MGAT5,-0.07066731689712122,stabilizing
+EWSR1,DTL,0.05853570371220528,destabilizing
+EWSR1,ALK,0.053914268198246094,destabilizing
+EWSR1,INPP4B,-0.05501436625065362,stabilizing
+EWSR1,LPP,-0.05376630604718984,stabilizing
+EWSR1,CCBE1,-0.0627725963940556,stabilizing
+FUS,EPB41L4B,-0.08198034170647223,stabilizing
+FUS,LRRTM4,-0.09028705519735827,stabilizing
+FUS,MGAT5,-0.05557315957301349,stabilizing
+FUS,CENPP,0.07655118966880824,destabilizing
+FUS,DTL,0.11996555666242702,destabilizing
+FUS,EPB41L5,-0.05832641019977979,stabilizing
+FUS,ALK,0.08094969573095763,destabilizing
+FUS,INPP4B,-0.07722949657732446,stabilizing
+FUS,CCBE1,-0.07723441604426382,stabilizing
+FUS,CNGB1,-0.06062385226683681,stabilizing
+FUS,RASA2,0.05341616828116052,destabilizing
+FUS,SCUBE1,-0.06010076942058004,stabilizing
+FUS,LRRC37A3,-0.04969187723500438,stabilizing
+FUS,ADGRB3,-0.04991980864063131,stabilizing
+SFPQ,CCBE1,-0.05688368510319105,stabilizing
+NOVA1,NOVA1,0.11063111394296661,destabilizing
+PRPF8,TOX,0.04998700594886065,destabilizing
+PRPF8,EYA4,0.05636149648669436,destabilizing
+PRPF8,EPB41L4B,-0.07277710201487832,stabilizing
+PRPF8,LRRTM4,-0.06031068218949107,stabilizing
+PRPF8,MGAT5,-0.07943560692850768,stabilizing
+PRPF8,CENPP,0.054303718165143226,destabilizing
+PRPF8,DTL,0.07870774165129105,destabilizing
+PRPF8,EPB41L5,-0.05213925008178564,stabilizing
+PRPF8,MARCKS,-0.05922309630826008,stabilizing
+PRPF8,ALK,0.08712165823878104,destabilizing
+PRPF8,ENAH,-0.05201410614133149,stabilizing
+PRPF8,INPP4B,-0.0783226978436124,stabilizing
+PRPF8,CCBE1,-0.07091504595328056,stabilizing
+PRPF8,DOCK4,-0.07814362014058737,stabilizing
+PRPF8,SCUBE1,-0.0863483768303677,stabilizing
+PRPF8,MAGI2,-0.06543317854798267,stabilizing
+PRPF8,AUTS2,-0.08401101869155872,stabilizing
+SNRNP200,TMTC2,0.06449030798531444,destabilizing
+SNRNP200,EYA4,0.05038913864751622,destabilizing
+SNRNP200,EPB41L4B,-0.08116683170835765,stabilizing
+SNRNP200,TBC1D5,-0.05403552016621211,stabilizing
+SNRNP200,LRRTM4,-0.06964947054636064,stabilizing
+SNRNP200,MGAT5,-0.06632167276888018,stabilizing
+SNRNP200,CENPP,0.05374395696342287,destabilizing
+SNRNP200,DTL,0.07779036939883181,destabilizing
+SNRNP200,PRKCB,-0.0598153011526946,stabilizing
+SNRNP200,ALK,0.08937624827974094,destabilizing
+SNRNP200,SIK3,0.05011619929405443,destabilizing
+SNRNP200,INPP4B,-0.09370530220116803,stabilizing
+SNRNP200,CCBE1,-0.0781824265096715,stabilizing
+SNRNP200,PRKN,-0.053586931143999754,stabilizing
+SNRNP200,FRMD4A,-0.049472441234948705,stabilizing
+SNRNP200,SCUBE1,-0.09030192448120566,stabilizing
+DDX5,MARCKS,0.08060601525489175,destabilizing
+DDX5,ARHGAP26,-0.05828735656260475,stabilizing
+DDX5,MBNL2,-0.06564891606554994,stabilizing
+DDX5,RBFOX1,-0.06043117864880935,stabilizing
+DDX6,SLC8A1,-0.049384634840345144,stabilizing
+DDX17,FAM171B,-0.05510685137324786,stabilizing
+DDX17,VAPA,-0.09199280415225282,stabilizing
+DDX17,ENSG00000228222,0.05329089123065595,destabilizing
+DDX17,SLC8A1,-0.06710541899678375,stabilizing
+DHX9,MGAT5,-0.05500122730300485,stabilizing
+DHX9,DTL,0.05532252508353641,destabilizing
+EIF4E,EIF4E,0.11778210905642605,destabilizing
+NCL,EPB41L4B,-0.049626829980219576,stabilizing
+NCL,LRRTM4,-0.05885518333620501,stabilizing
+NCL,CENPP,0.050899951976917594,destabilizing
+NCL,DTL,0.06328974575665924,destabilizing
+NCL,FAM171B,-0.051316590991448426,stabilizing
+NCL,ALK,0.05538398524155638,destabilizing
+NCL,INPP4B,-0.05769642246175087,stabilizing
+NCL,ERC1,-0.055951664274392195,stabilizing
+NCL,TCF12,-0.0755913165125633,stabilizing
+NCL,CCBE1,-0.0670735836243154,stabilizing
+NCL,VAPA,-0.05345853066905135,stabilizing
+NCL,SLC8A1,-0.0840010094496421,stabilizing
+YBX1,NCOA1,-0.05600317610828586,stabilizing
+YBX1,TMTC2,0.06767094843355567,destabilizing
+YBX1,TOX,0.06811053222976407,destabilizing
+YBX1,EPB41L4B,-0.06347281962183483,stabilizing
+YBX1,LRRTM4,-0.06861807997343912,stabilizing
+YBX1,MGAT5,-0.07350886919333458,stabilizing
+YBX1,CENPP,0.06254882076215279,destabilizing
+YBX1,PSME4,0.052514553257269475,destabilizing
+YBX1,EPHA5,-0.05696864614251079,stabilizing
+YBX1,DTL,0.11719916529253299,destabilizing
+YBX1,PRKCB,-0.050509598416678285,stabilizing
+YBX1,ALK,0.05982461519389887,destabilizing
+YBX1,INPP4B,-0.07473035502510138,stabilizing
+YBX1,CCBE1,-0.06815660421623117,stabilizing
+YBX1,VAPA,0.08678594935612685,destabilizing
+YBX1,LINC00174,-0.059884296107373475,stabilizing
+YBX1,PPM1E,0.06668864695535091,destabilizing
+YBX1,DOCK4,-0.06122615684088394,stabilizing
+YBX1,NEGR1,0.052871737634641945,destabilizing
+YBX1,SCUBE1,-0.08045392558659308,stabilizing
+YBX1,AUTS2,-0.05343519655604877,stabilizing
+RC3H1,RC3H1,-0.12323121152596496,stabilizing
+SYNCRIP,MGAT5,-0.05235732252249517,stabilizing
+SYNCRIP,SCUBE1,-0.05174808338248603,stabilizing
+TNRC6B,JMJD1C,-0.049737429522647654,stabilizing
+SNRPA,LRRTM4,-0.08318691267837489,stabilizing
+SNRPA,MGAT5,-0.05079837318406738,stabilizing
+SNRPA,CENPP,0.054382240200376325,destabilizing
+SNRPA,DTL,0.07542011294192902,destabilizing
+SNRPA,ALK,0.05722792070318103,destabilizing
+SNRPA,INPP4B,-0.057275700878137464,stabilizing
+SNRPA,SCUBE1,-0.05636428524631393,stabilizing
+G3BP1,MGAT5,-0.06098008501609782,stabilizing
+G3BP1,DTL,0.05474593952483652,destabilizing
+G3BP1,INPP4B,-0.06636056470980077,stabilizing
diff --git a/output/tier3/results/neuroblastoma_network_raw.csv b/output/tier3/results/neuroblastoma_network_raw.csv
new file mode 100644
index 0000000000000000000000000000000000000000..e48e052dae6251491c1ec68faad8089d7f1a87cf
--- /dev/null
+++ b/output/tier3/results/neuroblastoma_network_raw.csv
@@ -0,0 +1,9113 @@
+rbp,target,spearman_r,direction
+ELAVL1,DOC2B,0.06170518856402139,destabilizing
+ELAVL1,MTMR7,0.09541953599794255,destabilizing
+ELAVL1,FRY,0.08275015784205272,destabilizing
+ELAVL1,MACROD2,0.07515463415587913,destabilizing
+ELAVL1,CENPP,0.13099414391063174,destabilizing
+ELAVL1,KCNB2,0.0874134402166194,destabilizing
+ELAVL1,ALK,0.10845074758060333,destabilizing
+ELAVL1,XKR6,0.08060930270863335,destabilizing
+ELAVL1,MAGI3,0.0685827287499393,destabilizing
+ELAVL1,PTPRS,0.12092009805973968,destabilizing
+ELAVL1,DMD,0.08240132370159149,destabilizing
+ELAVL1,DOCK3,0.07705956509300137,destabilizing
+ELAVL1,FMN2,0.06423230535365858,destabilizing
+ELAVL1,WIPF2,0.07803415383414282,destabilizing
+ELAVL1,DLEU1,0.10978975827787135,destabilizing
+ELAVL1,LRRC37A3,0.07621884482922853,destabilizing
+ELAVL1,EYS,0.056213749722912126,destabilizing
+ELAVL1,MLLT3,0.08743773527820495,destabilizing
+ELAVL1,PTPRD,0.06449470348232847,destabilizing
+ELAVL1,FAM155A,0.11682121035485626,destabilizing
+ELAVL2,TRERF1,0.19995664996172338,destabilizing
+ELAVL2,SORCS1,0.1071637847161866,destabilizing
+ELAVL2,FCHSD2,0.06826001836935125,destabilizing
+ELAVL2,PDE3A,0.19488744725087215,destabilizing
+ELAVL2,UNC79,0.21135198785826453,destabilizing
+ELAVL2,DOC2B,0.13528841433751132,destabilizing
+ELAVL2,TMTC2,0.16184786275503046,destabilizing
+ELAVL2,KALRN,0.13022479079762067,destabilizing
+ELAVL2,CHD1,0.08773575099539563,destabilizing
+ELAVL2,UBE2E2,0.08656477964148,destabilizing
+ELAVL2,PPARD,0.09093301630048649,destabilizing
+ELAVL2,RYR2,0.1799596166496325,destabilizing
+ELAVL2,MTMR7,0.2027694027031937,destabilizing
+ELAVL2,EIF4E,0.13330077851126007,destabilizing
+ELAVL2,SOX11,0.06406793319154658,destabilizing
+ELAVL2,EPB41L4B,0.12756292822726947,destabilizing
+ELAVL2,CACNA1B,0.1172399809400547,destabilizing
+ELAVL2,LRRTM4,0.1275554461402376,destabilizing
+ELAVL2,SIRPA,0.1511374446819523,destabilizing
+ELAVL2,PTEN,0.11258993319489888,destabilizing
+ELAVL2,FRY,0.15666464058572174,destabilizing
+ELAVL2,MACROD2,0.1564062783896739,destabilizing
+ELAVL2,SHANK2,0.21982026964207912,destabilizing
+ELAVL2,CDK12,0.2111345711277809,destabilizing
+ELAVL2,RFX7,0.14310275076656237,destabilizing
+ELAVL2,UBR5,0.08528310767565926,destabilizing
+ELAVL2,JARID2,0.07001222209729568,destabilizing
+ELAVL2,MPHOSPH8,0.11673788667775374,destabilizing
+ELAVL2,DIP2C,0.12628658717579674,destabilizing
+ELAVL2,ZNF423,0.060720421214690866,destabilizing
+ELAVL2,UBR3,0.1256204160506263,destabilizing
+ELAVL2,MGAT5,0.05852734285703205,destabilizing
+ELAVL2,DLG2,0.09878660493706017,destabilizing
+ELAVL2,CHST12,0.21804719146222326,destabilizing
+ELAVL2,EML5,0.17932266478827327,destabilizing
+ELAVL2,CENPP,0.22068353823117828,destabilizing
+ELAVL2,PSME4,0.18198670387148205,destabilizing
+ELAVL2,TMEM106B,0.14189083761761764,destabilizing
+ELAVL2,EPHA5,0.14035833056236083,destabilizing
+ELAVL2,KCNB2,0.18069323539237528,destabilizing
+ELAVL2,ZNF83,0.11010420494470186,destabilizing
+ELAVL2,SOX6,0.09153921517539927,destabilizing
+ELAVL2,ZNF521,0.13571700152041719,destabilizing
+ELAVL2,PLEKHA5,0.09642455531449205,destabilizing
+ELAVL2,NOVA1,0.1631771398472102,destabilizing
+ELAVL2,CCNY,0.17681616959051075,destabilizing
+ELAVL2,ARIH1,0.12261499985200301,destabilizing
+ELAVL2,EPB41L5,0.10394949178540641,destabilizing
+ELAVL2,GPR158,0.15375750736996982,destabilizing
+ELAVL2,NCOA2,0.12298173176830254,destabilizing
+ELAVL2,ALK,0.14868203778144268,destabilizing
+ELAVL2,ARHGAP26,0.06329526761460275,destabilizing
+ELAVL2,CTNND2,0.0563838715851449,destabilizing
+ELAVL2,IFT172,0.15045169363809435,destabilizing
+ELAVL2,CCNT1,0.10786511419436552,destabilizing
+ELAVL2,DTWD2,0.16190179503440044,destabilizing
+ELAVL2,SIK3,0.14199633796298747,destabilizing
+ELAVL2,CPEB3,0.20678336852015186,destabilizing
+ELAVL2,CADM2,0.0808180660324484,destabilizing
+ELAVL2,XKR6,0.19042251466952265,destabilizing
+ELAVL2,CADPS,0.09217992793855667,destabilizing
+ELAVL2,FGF13,0.07529375141918149,destabilizing
+ELAVL2,TCF20,0.15788929924257386,destabilizing
+ELAVL2,CDKAL1,0.07549088544456528,destabilizing
+ELAVL2,DGKI,0.10335378265171499,destabilizing
+ELAVL2,EXOC6B,0.20950855769747448,destabilizing
+ELAVL2,MAGI3,0.1480756797154202,destabilizing
+ELAVL2,SBF2,0.09248071742840797,destabilizing
+ELAVL2,INPP4B,0.15164855882737147,destabilizing
+ELAVL2,PTPRS,0.14128845017386638,destabilizing
+ELAVL2,CBFA2T2,0.08755725186894003,destabilizing
+ELAVL2,SPDYE3,0.1425759585986195,destabilizing
+ELAVL2,TMEM178B,0.06346467028700195,destabilizing
+ELAVL2,DMD,0.2523650911086833,destabilizing
+ELAVL2,MCU,0.14607391760327085,destabilizing
+ELAVL2,SSH2,0.10650353857810747,destabilizing
+ELAVL2,DOCK3,0.18727451254970306,destabilizing
+ELAVL2,HS6ST3,0.1396764183969493,destabilizing
+ELAVL2,LPP,0.17896959934341622,destabilizing
+ELAVL2,STAG1,0.10942016765876829,destabilizing
+ELAVL2,CAPZA2,0.12865163977424507,destabilizing
+ELAVL2,ADGRL3,0.09250880215476018,destabilizing
+ELAVL2,UBE2R2,0.1506768099126112,destabilizing
+ELAVL2,GTF2IRD1,0.13605607231013248,destabilizing
+ELAVL2,CCBE1,0.08375023571677037,destabilizing
+ELAVL2,TTC28,0.11404916011302475,destabilizing
+ELAVL2,SBNO1,0.09796287884260255,destabilizing
+ELAVL2,RIMS2,0.08743293630814088,destabilizing
+ELAVL2,TRIO,0.06529704251811397,destabilizing
+ELAVL2,BTBD9,0.16237729320688346,destabilizing
+ELAVL2,CNGB1,0.18244208101549841,destabilizing
+ELAVL2,FMN2,0.14238249084871088,destabilizing
+ELAVL2,ENSG00000228222,0.19867404934899188,destabilizing
+ELAVL2,PRKN,0.2171680279217905,destabilizing
+ELAVL2,RASA2,0.12492443145296947,destabilizing
+ELAVL2,PPP1R12B,0.09310669709127292,destabilizing
+ELAVL2,FRMD4A,0.11408643144909289,destabilizing
+ELAVL2,CAMK1D,0.06271649086136115,destabilizing
+ELAVL2,SEMA6D,0.1343103699638489,destabilizing
+ELAVL2,WIPF2,0.16048420047029452,destabilizing
+ELAVL2,DLEU1,0.20296606627147143,destabilizing
+ELAVL2,TSHZ2,0.09363692212750602,destabilizing
+ELAVL2,MED13L,0.09225964032483358,destabilizing
+ELAVL2,KAZN,0.14062303169581608,destabilizing
+ELAVL2,KANSL1,0.11494978053183431,destabilizing
+ELAVL2,FRMD5,0.15614105094116656,destabilizing
+ELAVL2,LINC00174,0.12533861877089242,destabilizing
+ELAVL2,PPM1E,0.11998547395452214,destabilizing
+ELAVL2,ARL3,0.07941779617655952,destabilizing
+ELAVL2,MBD5,0.1314251551278435,destabilizing
+ELAVL2,ELAVL3,0.13320374511741825,destabilizing
+ELAVL2,SLIT2,0.17477810675143934,destabilizing
+ELAVL2,CLASP1,0.11849973842175099,destabilizing
+ELAVL2,UNC5C,0.14117260782637658,destabilizing
+ELAVL2,CACNA2D3,-0.05377637939202361,stabilizing
+ELAVL2,RC3H1,0.10905445271652013,destabilizing
+ELAVL2,NEGR1,0.1370902975474068,destabilizing
+ELAVL2,ENOX1,0.18779612477970709,destabilizing
+ELAVL2,SCUBE1,0.08609267918147862,destabilizing
+ELAVL2,GPHN,0.11696996305508427,destabilizing
+ELAVL2,NAV3,0.15508556577271676,destabilizing
+ELAVL2,TOMM22,0.16068929828692763,destabilizing
+ELAVL2,ANKFN1,0.05820602918434517,destabilizing
+ELAVL2,MAGI2,0.07189851016930174,destabilizing
+ELAVL2,LSAMP,0.0582666480172048,destabilizing
+ELAVL2,AKAP6,0.16857392657785772,destabilizing
+ELAVL2,TMED2,0.09060102983850593,destabilizing
+ELAVL2,ZBTB20,0.15233273351643462,destabilizing
+ELAVL2,GRIK2,0.11848887580383309,destabilizing
+ELAVL2,SOX5,0.10050120708136763,destabilizing
+ELAVL2,LRRC37A3,0.1960977165711625,destabilizing
+ELAVL2,TMEM132C,0.052158476283167755,destabilizing
+ELAVL2,EYS,0.12517256334267363,destabilizing
+ELAVL2,ARID1B,0.0894069974350223,destabilizing
+ELAVL2,PRKCE,0.11843687351131231,destabilizing
+ELAVL2,RBFOX1,-0.07727177739201731,stabilizing
+ELAVL2,SDK1,0.09897661669777139,destabilizing
+ELAVL2,NRG1,0.0787115531685712,destabilizing
+ELAVL2,MLLT3,0.1879545636933313,destabilizing
+ELAVL2,FMN1,0.08139100002379013,destabilizing
+ELAVL2,ADGRB3,0.09802317207468589,destabilizing
+ELAVL2,ROBO1,0.14960202732270353,destabilizing
+ELAVL2,SYPL1,0.0570391885384173,destabilizing
+ELAVL2,PTPRD,0.13491081257079557,destabilizing
+ELAVL2,FAM155A,0.13975993115610924,destabilizing
+ELAVL2,LARP1B,0.14911288373543194,destabilizing
+ELAVL3,DGKI,0.06792657446801396,destabilizing
+ELAVL3,DOCK3,0.0855697316048488,destabilizing
+ELAVL3,ELAVL3,-0.2831660638202642,stabilizing
+ELAVL4,TRERF1,0.2752751835389776,destabilizing
+ELAVL4,SORCS1,0.161130198665874,destabilizing
+ELAVL4,NCOA1,0.07094426549526142,destabilizing
+ELAVL4,COPA,0.10732203028393335,destabilizing
+ELAVL4,FCHSD2,0.12812385612010616,destabilizing
+ELAVL4,PDE3A,0.2534872445777657,destabilizing
+ELAVL4,UNC79,0.2681335694231452,destabilizing
+ELAVL4,DOC2B,0.2006185938705801,destabilizing
+ELAVL4,TMTC2,0.24266805756500381,destabilizing
+ELAVL4,KALRN,0.17649063454381916,destabilizing
+ELAVL4,CHD1,0.13721449338915614,destabilizing
+ELAVL4,PAK3,0.07180027772902767,destabilizing
+ELAVL4,UBE2E2,0.10526901012105859,destabilizing
+ELAVL4,PPARD,0.1492202375293546,destabilizing
+ELAVL4,TOX,0.08355753451803952,destabilizing
+ELAVL4,BRAF,0.07407453361426407,destabilizing
+ELAVL4,RYR2,0.2730732597089723,destabilizing
+ELAVL4,MTMR7,0.28141640028277254,destabilizing
+ELAVL4,EIF4E,0.22553474499061255,destabilizing
+ELAVL4,SOX11,0.07695698576400375,destabilizing
+ELAVL4,EPB41L4B,0.1695745587802582,destabilizing
+ELAVL4,CACNA1B,0.16766257245806201,destabilizing
+ELAVL4,TBC1D5,0.08773437554423902,destabilizing
+ELAVL4,LRRTM4,0.17416633125492784,destabilizing
+ELAVL4,SIRPA,0.18875901825201133,destabilizing
+ELAVL4,PTEN,0.16257360555645026,destabilizing
+ELAVL4,FRY,0.2688463090375234,destabilizing
+ELAVL4,MACROD2,0.2266953705697661,destabilizing
+ELAVL4,FOXN3,0.08442238689385796,destabilizing
+ELAVL4,SHANK2,0.31778773962450163,destabilizing
+ELAVL4,CDK12,0.30067442186554405,destabilizing
+ELAVL4,RFX7,0.2196213791736626,destabilizing
+ELAVL4,UBR5,0.12244301129750917,destabilizing
+ELAVL4,JARID2,0.12905953959073932,destabilizing
+ELAVL4,MPHOSPH8,0.17841666747628707,destabilizing
+ELAVL4,DIP2C,0.1645739110805471,destabilizing
+ELAVL4,ZNF423,0.09688280236656512,destabilizing
+ELAVL4,UBR3,0.19262234179574367,destabilizing
+ELAVL4,MGAT5,0.11396631965975325,destabilizing
+ELAVL4,DLG2,0.16786007280097828,destabilizing
+ELAVL4,CHST12,0.3695507711634472,destabilizing
+ELAVL4,EML5,0.2589488161893674,destabilizing
+ELAVL4,CENPP,0.2344978738712039,destabilizing
+ELAVL4,PSME4,0.21850641286792044,destabilizing
+ELAVL4,TMEM106B,0.2814811145790299,destabilizing
+ELAVL4,RABGAP1L,0.06248894797200443,destabilizing
+ELAVL4,EPHA5,0.16807256129706843,destabilizing
+ELAVL4,KCNB2,0.27140174563109604,destabilizing
+ELAVL4,ZNF83,0.15606634288781504,destabilizing
+ELAVL4,SOX6,0.14443423170310393,destabilizing
+ELAVL4,ZNF521,0.24775538003258712,destabilizing
+ELAVL4,PLEKHA5,0.15019110880833667,destabilizing
+ELAVL4,DTL,0.1333696081650369,destabilizing
+ELAVL4,NOVA1,0.28835927334059264,destabilizing
+ELAVL4,CCNY,0.23290932678619938,destabilizing
+ELAVL4,ARIH1,0.1722087789116643,destabilizing
+ELAVL4,FAM171B,0.05149448564535301,destabilizing
+ELAVL4,EPB41L5,0.20079865993029625,destabilizing
+ELAVL4,GPR158,0.23622256180383422,destabilizing
+ELAVL4,NCOA2,0.1839752567671657,destabilizing
+ELAVL4,ALK,0.21128380274255226,destabilizing
+ELAVL4,ACACA,0.10369268511466496,destabilizing
+ELAVL4,ARHGAP26,0.07035364199949193,destabilizing
+ELAVL4,CTNND2,0.10507562016484072,destabilizing
+ELAVL4,IFT172,0.2387811931994486,destabilizing
+ELAVL4,CCNT1,0.14745795251108496,destabilizing
+ELAVL4,DTWD2,0.333771264164,destabilizing
+ELAVL4,SIK3,0.1738952802360539,destabilizing
+ELAVL4,CPEB3,0.23535170268380035,destabilizing
+ELAVL4,CADM2,0.12288888470338807,destabilizing
+ELAVL4,XKR6,0.28019154763661613,destabilizing
+ELAVL4,RMND5A,0.08666161137613011,destabilizing
+ELAVL4,CADPS,0.12548547046156555,destabilizing
+ELAVL4,FGF13,0.08555572699874488,destabilizing
+ELAVL4,TCF20,0.2456233950897215,destabilizing
+ELAVL4,CDKAL1,0.12916780761004443,destabilizing
+ELAVL4,DGKI,0.18816513311035118,destabilizing
+ELAVL4,EXOC6B,0.30909057308565113,destabilizing
+ELAVL4,MAGI3,0.21464655719475007,destabilizing
+ELAVL4,SBF2,0.12450415666855542,destabilizing
+ELAVL4,INPP4B,0.19618399064252276,destabilizing
+ELAVL4,ERC1,0.10325695708771204,destabilizing
+ELAVL4,PTPRS,0.2863456954940076,destabilizing
+ELAVL4,CBFA2T2,0.1238622943322127,destabilizing
+ELAVL4,SPDYE3,0.21971945158305137,destabilizing
+ELAVL4,TMEM178B,0.13402385146337017,destabilizing
+ELAVL4,KMT2C,0.06353166918752759,destabilizing
+ELAVL4,CACNA2D1,0.07094619811609522,destabilizing
+ELAVL4,DMD,0.36725925776844176,destabilizing
+ELAVL4,EIF4G3,0.08309464007472586,destabilizing
+ELAVL4,MCU,0.19995752618873328,destabilizing
+ELAVL4,SSH2,0.1707099844902012,destabilizing
+ELAVL4,TCF12,0.056128414481673126,destabilizing
+ELAVL4,DOCK3,0.24942886208681211,destabilizing
+ELAVL4,HS6ST3,0.23805268734377077,destabilizing
+ELAVL4,LPP,0.25646118677286656,destabilizing
+ELAVL4,STAG1,0.19252653579823747,destabilizing
+ELAVL4,CAPZA2,0.20084147318438322,destabilizing
+ELAVL4,ADGRL3,0.12328291465925677,destabilizing
+ELAVL4,PHACTR1,0.10604919819644873,destabilizing
+ELAVL4,UBE2R2,0.245020522837232,destabilizing
+ELAVL4,GTF2IRD1,0.2030598422996969,destabilizing
+ELAVL4,CCBE1,0.11811950793734435,destabilizing
+ELAVL4,FTX,0.0871181395926112,destabilizing
+ELAVL4,JMJD1C,0.052487000931197514,destabilizing
+ELAVL4,TTC28,0.1268188875887832,destabilizing
+ELAVL4,SBNO1,0.1520872642150029,destabilizing
+ELAVL4,RIMS2,0.1234252714918207,destabilizing
+ELAVL4,IGF1R,0.0958012470984546,destabilizing
+ELAVL4,TRIO,0.10390169146181742,destabilizing
+ELAVL4,KCND2,0.07834812784643169,destabilizing
+ELAVL4,BTBD9,0.21427869157468896,destabilizing
+ELAVL4,CNGB1,0.2928688889927879,destabilizing
+ELAVL4,FMN2,0.18050780612781847,destabilizing
+ELAVL4,ENSG00000228222,0.33610040184422696,destabilizing
+ELAVL4,ATXN1,0.08535651130547069,destabilizing
+ELAVL4,SYN3,0.06005713622698862,destabilizing
+ELAVL4,PRKN,0.26027856127128673,destabilizing
+ELAVL4,RASA2,0.2399342865838883,destabilizing
+ELAVL4,PPP1R12B,0.15594142919558043,destabilizing
+ELAVL4,FRMD4A,0.1902210563880423,destabilizing
+ELAVL4,CAMK1D,0.08842033405602784,destabilizing
+ELAVL4,PARD3,0.06695511186494099,destabilizing
+ELAVL4,SEMA6D,0.19965484905685296,destabilizing
+ELAVL4,WIPF2,0.209745774962594,destabilizing
+ELAVL4,DLEU1,0.28751313684696034,destabilizing
+ELAVL4,TSHZ2,0.1370651824819836,destabilizing
+ELAVL4,MED13L,0.16375261222904944,destabilizing
+ELAVL4,AFF3,0.07704379968218947,destabilizing
+ELAVL4,KAZN,0.2045313695189678,destabilizing
+ELAVL4,KANSL1,0.14519909063434192,destabilizing
+ELAVL4,FRMD5,0.18284877613696887,destabilizing
+ELAVL4,LINC00174,0.21649345770483552,destabilizing
+ELAVL4,PPM1E,0.2038248285557271,destabilizing
+ELAVL4,ARL3,0.14911361380376806,destabilizing
+ELAVL4,MBD5,0.17935527616372274,destabilizing
+ELAVL4,ELAVL3,0.20710912741376922,destabilizing
+ELAVL4,SLIT2,0.2842926705850459,destabilizing
+ELAVL4,SLC8A1,0.06867891168140931,destabilizing
+ELAVL4,CLASP1,0.1488283910744024,destabilizing
+ELAVL4,DOCK4,0.051946092051911426,destabilizing
+ELAVL4,UNC5C,0.20042125927296245,destabilizing
+ELAVL4,CACNA2D3,-0.10820847650955501,stabilizing
+ELAVL4,RC3H1,0.16476242394954976,destabilizing
+ELAVL4,NEGR1,0.22985323644569186,destabilizing
+ELAVL4,ENOX1,0.30217266670516013,destabilizing
+ELAVL4,SCUBE1,0.13946162347708765,destabilizing
+ELAVL4,GPHN,0.17070204233206,destabilizing
+ELAVL4,NAV3,0.24853300337343767,destabilizing
+ELAVL4,EBF1,0.10250177167468241,destabilizing
+ELAVL4,TOMM22,0.23337428531804916,destabilizing
+ELAVL4,MBNL2,0.10027930281443055,destabilizing
+ELAVL4,ANKFN1,0.07273237257490613,destabilizing
+ELAVL4,MAGI2,0.10902263985712789,destabilizing
+ELAVL4,LSAMP,0.13498006309706292,destabilizing
+ELAVL4,AKAP6,0.2191096523179601,destabilizing
+ELAVL4,TMED2,0.15205489560617272,destabilizing
+ELAVL4,ZBTB20,0.20262821738049222,destabilizing
+ELAVL4,GRIK2,0.20991103073695416,destabilizing
+ELAVL4,SOX5,0.15505280792497877,destabilizing
+ELAVL4,LRRC37A3,0.28479009331859423,destabilizing
+ELAVL4,TMEM132C,0.07809699110745427,destabilizing
+ELAVL4,EYS,0.18138349423169844,destabilizing
+ELAVL4,ARID1B,0.16498938913733244,destabilizing
+ELAVL4,PRKCE,0.15480684845512196,destabilizing
+ELAVL4,RBFOX1,-0.1117585124163893,stabilizing
+ELAVL4,SDK1,0.11896286522494412,destabilizing
+ELAVL4,NRG1,0.08871252490846951,destabilizing
+ELAVL4,MLLT3,0.3012932292493041,destabilizing
+ELAVL4,FMN1,0.13886300487649364,destabilizing
+ELAVL4,ADGRB3,0.1396145964977271,destabilizing
+ELAVL4,ROBO1,0.21642001315292658,destabilizing
+ELAVL4,SYPL1,0.117964511522904,destabilizing
+ELAVL4,PTPRD,0.19723517454277098,destabilizing
+ELAVL4,FAM155A,0.1925094633112759,destabilizing
+ELAVL4,LARP1B,0.21207158109981475,destabilizing
+HNRNPA2B1,TRERF1,0.2610031489047995,destabilizing
+HNRNPA2B1,SORCS1,0.13738968755005407,destabilizing
+HNRNPA2B1,COPA,0.08710899398455185,destabilizing
+HNRNPA2B1,FCHSD2,0.11688686577430424,destabilizing
+HNRNPA2B1,PDE3A,0.15715430138991948,destabilizing
+HNRNPA2B1,UNC79,0.27059328753129636,destabilizing
+HNRNPA2B1,DOC2B,0.17883993147665944,destabilizing
+HNRNPA2B1,TMTC2,0.2690870707561141,destabilizing
+HNRNPA2B1,KALRN,0.1602096103192483,destabilizing
+HNRNPA2B1,CHD1,0.10247493352902172,destabilizing
+HNRNPA2B1,PAK3,0.06745416856760363,destabilizing
+HNRNPA2B1,UBE2E2,0.0904953616612898,destabilizing
+HNRNPA2B1,PPARD,0.12177600617657018,destabilizing
+HNRNPA2B1,TOX,0.10615821383965869,destabilizing
+HNRNPA2B1,BRAF,0.11356125817274905,destabilizing
+HNRNPA2B1,RYR2,0.24739218977800773,destabilizing
+HNRNPA2B1,MTMR7,0.27900400609209886,destabilizing
+HNRNPA2B1,EIF4E,0.2842430463600914,destabilizing
+HNRNPA2B1,SOX11,0.07747494788732077,destabilizing
+HNRNPA2B1,EPB41L4B,0.10983644542376376,destabilizing
+HNRNPA2B1,CACNA1B,0.16353203204532493,destabilizing
+HNRNPA2B1,TBC1D5,0.07554413725318394,destabilizing
+HNRNPA2B1,WSB1,0.0770588692472026,destabilizing
+HNRNPA2B1,LRRTM4,0.11875000728057106,destabilizing
+HNRNPA2B1,SIRPA,0.11550650222973459,destabilizing
+HNRNPA2B1,PTEN,0.14180672742467373,destabilizing
+HNRNPA2B1,SPPL3,0.07594545986713785,destabilizing
+HNRNPA2B1,FRY,0.29993536605870363,destabilizing
+HNRNPA2B1,RUNX1T1,0.11431854882787412,destabilizing
+HNRNPA2B1,MACROD2,0.25121266409583143,destabilizing
+HNRNPA2B1,SHANK2,0.2821621433047515,destabilizing
+HNRNPA2B1,CDK12,0.3959933651625223,destabilizing
+HNRNPA2B1,BMPR1B,0.052413293351886985,destabilizing
+HNRNPA2B1,RFX7,0.22180876896504065,destabilizing
+HNRNPA2B1,UBR5,0.06190913246204633,destabilizing
+HNRNPA2B1,JARID2,0.10637803507460011,destabilizing
+HNRNPA2B1,MPHOSPH8,0.2579484131006539,destabilizing
+HNRNPA2B1,DIP2C,0.14623672311215524,destabilizing
+HNRNPA2B1,ZNF423,0.09432970746276322,destabilizing
+HNRNPA2B1,UBR3,0.13243603376633492,destabilizing
+HNRNPA2B1,DLG2,0.17341517144134275,destabilizing
+HNRNPA2B1,CHST12,0.3748323142750196,destabilizing
+HNRNPA2B1,EML5,0.23433406231370055,destabilizing
+HNRNPA2B1,CENPP,0.49183205676936975,destabilizing
+HNRNPA2B1,PSME4,0.17183243960352002,destabilizing
+HNRNPA2B1,TMEM106B,0.21859804795387625,destabilizing
+HNRNPA2B1,RABGAP1L,0.07066430190783642,destabilizing
+HNRNPA2B1,EPHA5,0.1829180954942237,destabilizing
+HNRNPA2B1,KCNB2,0.35716475843119677,destabilizing
+HNRNPA2B1,ZNF83,0.18285500795760265,destabilizing
+HNRNPA2B1,SOX6,0.20388817243130875,destabilizing
+HNRNPA2B1,ZNF521,0.2216256435433421,destabilizing
+HNRNPA2B1,PLEKHA5,0.13505269830970862,destabilizing
+HNRNPA2B1,DTL,-0.1769211744631474,stabilizing
+HNRNPA2B1,NOVA1,0.3026964845590675,destabilizing
+HNRNPA2B1,CCNY,0.23554933122985994,destabilizing
+HNRNPA2B1,ARIH1,0.14569593557642022,destabilizing
+HNRNPA2B1,FAM171B,0.05635021887895639,destabilizing
+HNRNPA2B1,EPB41L5,0.1181230127573864,destabilizing
+HNRNPA2B1,GPR158,0.2142683744023116,destabilizing
+HNRNPA2B1,NCOA2,0.11872133166255683,destabilizing
+HNRNPA2B1,MARCKS,0.083420929457227,destabilizing
+HNRNPA2B1,ALK,0.4486625702957564,destabilizing
+HNRNPA2B1,ACACA,0.06677559568758186,destabilizing
+HNRNPA2B1,ARHGAP26,0.0572101919220396,destabilizing
+HNRNPA2B1,CTNND2,0.07150590553188617,destabilizing
+HNRNPA2B1,IFT172,0.25622649783591395,destabilizing
+HNRNPA2B1,CCNT1,0.14608950539660778,destabilizing
+HNRNPA2B1,DTWD2,0.39038084787694327,destabilizing
+HNRNPA2B1,SIK3,0.16248127356083178,destabilizing
+HNRNPA2B1,CPEB3,0.26053219707468944,destabilizing
+HNRNPA2B1,CADM2,0.13780255283490828,destabilizing
+HNRNPA2B1,XKR6,0.26177667817562544,destabilizing
+HNRNPA2B1,RMND5A,0.08375615672638996,destabilizing
+HNRNPA2B1,CADPS,0.14218665574067066,destabilizing
+HNRNPA2B1,FGF13,0.12081016805771538,destabilizing
+HNRNPA2B1,TCF20,0.16588420691380176,destabilizing
+HNRNPA2B1,CDKAL1,0.1648396233273334,destabilizing
+HNRNPA2B1,DGKI,0.19646082725009614,destabilizing
+HNRNPA2B1,EXOC6B,0.24913973660293287,destabilizing
+HNRNPA2B1,MAGI3,0.2611121890287891,destabilizing
+HNRNPA2B1,SBF2,0.1229851787040934,destabilizing
+HNRNPA2B1,INPP4B,0.1645065873180578,destabilizing
+HNRNPA2B1,PTPRS,0.24155031082294504,destabilizing
+HNRNPA2B1,CBFA2T2,0.09377807262580072,destabilizing
+HNRNPA2B1,SPDYE3,0.11678673095604458,destabilizing
+HNRNPA2B1,TMEM178B,0.11979920103370674,destabilizing
+HNRNPA2B1,DMD,0.32589481893176814,destabilizing
+HNRNPA2B1,EIF4G3,0.08683348227408878,destabilizing
+HNRNPA2B1,MCU,0.16743325735509293,destabilizing
+HNRNPA2B1,SSH2,0.18872306626825722,destabilizing
+HNRNPA2B1,DOCK3,0.2864017692583704,destabilizing
+HNRNPA2B1,HS6ST3,0.13824911200777967,destabilizing
+HNRNPA2B1,LPP,0.16946154235851377,destabilizing
+HNRNPA2B1,STAG1,0.15807223751200078,destabilizing
+HNRNPA2B1,CAPZA2,0.2493283648075011,destabilizing
+HNRNPA2B1,ADGRL3,0.1251225284577793,destabilizing
+HNRNPA2B1,PHACTR1,0.16115373603416838,destabilizing
+HNRNPA2B1,UBE2R2,0.23255860208615414,destabilizing
+HNRNPA2B1,GTF2IRD1,0.14646896973369217,destabilizing
+HNRNPA2B1,CCBE1,0.0541598075944536,destabilizing
+HNRNPA2B1,FTX,0.08237302892212409,destabilizing
+HNRNPA2B1,VAPA,0.08796949770150843,destabilizing
+HNRNPA2B1,JMJD1C,0.08334114929096585,destabilizing
+HNRNPA2B1,TTC28,0.20273076197551765,destabilizing
+HNRNPA2B1,SBNO1,0.09854495669941037,destabilizing
+HNRNPA2B1,RIMS2,0.17090050994475103,destabilizing
+HNRNPA2B1,IGF1R,0.05986556916380853,destabilizing
+HNRNPA2B1,KCND2,0.0628877923143634,destabilizing
+HNRNPA2B1,BTBD9,0.18278798869354024,destabilizing
+HNRNPA2B1,CNGB1,0.23521470202227573,destabilizing
+HNRNPA2B1,FMN2,0.16123771569895506,destabilizing
+HNRNPA2B1,ENSG00000228222,0.35666731108995503,destabilizing
+HNRNPA2B1,ATXN1,0.09351375252450056,destabilizing
+HNRNPA2B1,SYN3,0.1100631541570487,destabilizing
+HNRNPA2B1,PRKN,0.1957465657743073,destabilizing
+HNRNPA2B1,RASA2,0.27730051913744724,destabilizing
+HNRNPA2B1,PPP1R12B,0.1514822700758653,destabilizing
+HNRNPA2B1,FRMD4A,0.15375448698130176,destabilizing
+HNRNPA2B1,PARD3,0.06007647395591043,destabilizing
+HNRNPA2B1,SEMA6D,0.2137360173359014,destabilizing
+HNRNPA2B1,WIPF2,0.2678051662757599,destabilizing
+HNRNPA2B1,DLEU1,0.24033996341876182,destabilizing
+HNRNPA2B1,TSHZ2,0.15059495609790594,destabilizing
+HNRNPA2B1,MED13L,0.10275269873158852,destabilizing
+HNRNPA2B1,AFF3,0.07910498263027706,destabilizing
+HNRNPA2B1,KAZN,0.14232249353701965,destabilizing
+HNRNPA2B1,KANSL1,0.13718622261555735,destabilizing
+HNRNPA2B1,FRMD5,0.16690137740587685,destabilizing
+HNRNPA2B1,LINC00174,0.2580732221889417,destabilizing
+HNRNPA2B1,PPM1E,0.12324535437854128,destabilizing
+HNRNPA2B1,ARL3,0.20654593456120152,destabilizing
+HNRNPA2B1,MBD5,0.18480742373601378,destabilizing
+HNRNPA2B1,ELAVL3,0.2218416062232805,destabilizing
+HNRNPA2B1,SLIT2,0.2323888192451743,destabilizing
+HNRNPA2B1,CLASP1,0.16716909376240824,destabilizing
+HNRNPA2B1,UNC5C,0.20941900231323088,destabilizing
+HNRNPA2B1,CACNA2D3,-0.07433399322209389,stabilizing
+HNRNPA2B1,RC3H1,0.11498280020701937,destabilizing
+HNRNPA2B1,NEGR1,0.2653782071019182,destabilizing
+HNRNPA2B1,ENOX1,0.31943165964636244,destabilizing
+HNRNPA2B1,SCUBE1,0.09849179580505825,destabilizing
+HNRNPA2B1,GPHN,0.13131620242385023,destabilizing
+HNRNPA2B1,NAV3,0.1900968977003605,destabilizing
+HNRNPA2B1,EBF1,0.09828329159745931,destabilizing
+HNRNPA2B1,TOMM22,0.27501027675217976,destabilizing
+HNRNPA2B1,MBNL2,0.06663660978167979,destabilizing
+HNRNPA2B1,ANKFN1,0.12886200614199417,destabilizing
+HNRNPA2B1,MAGI2,0.07916946335766871,destabilizing
+HNRNPA2B1,LSAMP,0.1440570055243169,destabilizing
+HNRNPA2B1,AKAP6,0.19086972702851146,destabilizing
+HNRNPA2B1,TMED2,0.16881462462912106,destabilizing
+HNRNPA2B1,ZBTB20,0.21253595307518777,destabilizing
+HNRNPA2B1,GRIK2,0.1843141248063325,destabilizing
+HNRNPA2B1,MAML3,0.06317534065067265,destabilizing
+HNRNPA2B1,SOX5,0.13909471982547658,destabilizing
+HNRNPA2B1,LRRC37A3,0.32938076798906046,destabilizing
+HNRNPA2B1,TMEM132C,0.08812308511180118,destabilizing
+HNRNPA2B1,EYS,0.15929803484640254,destabilizing
+HNRNPA2B1,ARID1B,0.11796369187179555,destabilizing
+HNRNPA2B1,PRKCE,0.11722964000861597,destabilizing
+HNRNPA2B1,RBFOX1,-0.11997910749953976,stabilizing
+HNRNPA2B1,SDK1,0.10390747475001243,destabilizing
+HNRNPA2B1,NRG1,0.10293736396598212,destabilizing
+HNRNPA2B1,RORA,0.10255004057747803,destabilizing
+HNRNPA2B1,MLLT3,0.37208253035881145,destabilizing
+HNRNPA2B1,FMN1,0.08935168216464462,destabilizing
+HNRNPA2B1,ADGRB3,0.10750054510577844,destabilizing
+HNRNPA2B1,ROBO1,0.12591752462662417,destabilizing
+HNRNPA2B1,SYPL1,0.17095727297350713,destabilizing
+HNRNPA2B1,PTPRD,0.20648123560041193,destabilizing
+HNRNPA2B1,FAM155A,0.23583910019460153,destabilizing
+HNRNPA2B1,LARP1B,0.17577355644246162,destabilizing
+HNRNPC,TRERF1,0.231060398109268,destabilizing
+HNRNPC,SORCS1,0.11298729730826211,destabilizing
+HNRNPC,NCOA1,0.0786026270195814,destabilizing
+HNRNPC,COPA,0.09763663447020482,destabilizing
+HNRNPC,FCHSD2,0.10522132289126476,destabilizing
+HNRNPC,PDE3A,0.2125265048199512,destabilizing
+HNRNPC,UNC79,0.2353038321989986,destabilizing
+HNRNPC,DOC2B,0.1639483067467411,destabilizing
+HNRNPC,TMTC2,0.222448906315073,destabilizing
+HNRNPC,KALRN,0.1324255801309177,destabilizing
+HNRNPC,CHD1,0.11268822789617433,destabilizing
+HNRNPC,PAK3,0.05539975578117921,destabilizing
+HNRNPC,UBE2E2,0.060277537200109525,destabilizing
+HNRNPC,PPARD,0.11714594452417207,destabilizing
+HNRNPC,TOX,0.10355901461501267,destabilizing
+HNRNPC,BRAF,0.08596668189071004,destabilizing
+HNRNPC,RYR2,0.1811083826050357,destabilizing
+HNRNPC,MTMR7,0.257767590734214,destabilizing
+HNRNPC,EIF4E,0.23330189562676928,destabilizing
+HNRNPC,SOX11,0.08418868482404689,destabilizing
+HNRNPC,EPB41L4B,0.11677766633631571,destabilizing
+HNRNPC,CACNA1B,0.16024821698980202,destabilizing
+HNRNPC,TBC1D5,0.06595928560789682,destabilizing
+HNRNPC,LRRTM4,0.14166227613169935,destabilizing
+HNRNPC,SIRPA,0.150131983501036,destabilizing
+HNRNPC,PTEN,0.13211116722808958,destabilizing
+HNRNPC,FRY,0.24383759472879638,destabilizing
+HNRNPC,RUNX1T1,0.08478469369589214,destabilizing
+HNRNPC,MACROD2,0.2117867195374158,destabilizing
+HNRNPC,SHANK2,0.24925995224706385,destabilizing
+HNRNPC,CDK12,0.2882165767715756,destabilizing
+HNRNPC,RFX7,0.2246633038055398,destabilizing
+HNRNPC,UBR5,0.07643522897521521,destabilizing
+HNRNPC,JARID2,0.09653504054412107,destabilizing
+HNRNPC,MPHOSPH8,0.20421808347708045,destabilizing
+HNRNPC,DIP2C,0.1269695901891174,destabilizing
+HNRNPC,ZNF423,0.07483723457396169,destabilizing
+HNRNPC,UBR3,0.12428948215220469,destabilizing
+HNRNPC,MGAT5,0.06307355579017639,destabilizing
+HNRNPC,DLG2,0.1369152207380881,destabilizing
+HNRNPC,CHST12,0.3193528261848278,destabilizing
+HNRNPC,EML5,0.22011180308044107,destabilizing
+HNRNPC,CENPP,0.3132990934812013,destabilizing
+HNRNPC,PSME4,0.17379799185279324,destabilizing
+HNRNPC,TMEM106B,0.1923096244319849,destabilizing
+HNRNPC,EPHA5,0.1600733941162831,destabilizing
+HNRNPC,KCNB2,0.23976541478833205,destabilizing
+HNRNPC,ZNF83,0.14142778881730275,destabilizing
+HNRNPC,SOX6,0.1503449223946514,destabilizing
+HNRNPC,ZNF521,0.1826212930423379,destabilizing
+HNRNPC,PLEKHA5,0.1390551175092279,destabilizing
+HNRNPC,NOVA1,0.24164424972225035,destabilizing
+HNRNPC,CCNY,0.20616935283216276,destabilizing
+HNRNPC,ARIH1,0.12876841632481287,destabilizing
+HNRNPC,FAM171B,0.06346846580134356,destabilizing
+HNRNPC,EPB41L5,0.13787802380122893,destabilizing
+HNRNPC,GPR158,0.19496017061792228,destabilizing
+HNRNPC,NCOA2,0.118948445197823,destabilizing
+HNRNPC,MARCKS,0.07242839833153404,destabilizing
+HNRNPC,ALK,0.24214423719124664,destabilizing
+HNRNPC,ACACA,0.0962680762998523,destabilizing
+HNRNPC,CTNND2,0.09059230508397008,destabilizing
+HNRNPC,IFT172,0.20178349259962086,destabilizing
+HNRNPC,CCNT1,0.12600208946960695,destabilizing
+HNRNPC,DTWD2,0.3229522248362295,destabilizing
+HNRNPC,SIK3,0.1107507178968132,destabilizing
+HNRNPC,CPEB3,0.24547570279231842,destabilizing
+HNRNPC,CADM2,0.10174412625960476,destabilizing
+HNRNPC,XKR6,0.2190170545638579,destabilizing
+HNRNPC,RMND5A,0.07901408806611272,destabilizing
+HNRNPC,CADPS,0.11863089308977896,destabilizing
+HNRNPC,FGF13,0.08840118429014027,destabilizing
+HNRNPC,TCF20,0.18788269349051878,destabilizing
+HNRNPC,CDKAL1,0.11125736592696774,destabilizing
+HNRNPC,DGKI,0.14718952454002743,destabilizing
+HNRNPC,EXOC6B,0.23249918629808167,destabilizing
+HNRNPC,MAGI3,0.20919569317337025,destabilizing
+HNRNPC,SBF2,0.10690541313709855,destabilizing
+HNRNPC,INPP4B,0.1620490466288748,destabilizing
+HNRNPC,ERC1,0.07161995740031402,destabilizing
+HNRNPC,PTPRS,0.19909193605176154,destabilizing
+HNRNPC,CBFA2T2,0.08869175714321405,destabilizing
+HNRNPC,SPDYE3,0.12978298080917536,destabilizing
+HNRNPC,TMEM178B,0.09766975480570077,destabilizing
+HNRNPC,DMD,0.2803405326559565,destabilizing
+HNRNPC,EIF4G3,0.08832020913117727,destabilizing
+HNRNPC,MCU,0.13605356863488502,destabilizing
+HNRNPC,SSH2,0.15378521752408086,destabilizing
+HNRNPC,DOCK3,0.2307671513798443,destabilizing
+HNRNPC,HS6ST3,0.1772175929421168,destabilizing
+HNRNPC,LPP,0.1668013370762488,destabilizing
+HNRNPC,STAG1,0.13471684624203048,destabilizing
+HNRNPC,CAPZA2,0.19296655288281558,destabilizing
+HNRNPC,ADGRL3,0.1031360772632482,destabilizing
+HNRNPC,PHACTR1,0.10413432301465649,destabilizing
+HNRNPC,UBE2R2,0.18147870367494856,destabilizing
+HNRNPC,GTF2IRD1,0.14869290859815665,destabilizing
+HNRNPC,CCBE1,0.07841603195689306,destabilizing
+HNRNPC,FTX,0.08039272118185228,destabilizing
+HNRNPC,VAPA,0.07525004599932969,destabilizing
+HNRNPC,JMJD1C,0.0635375830056763,destabilizing
+HNRNPC,TTC28,0.14145730606413626,destabilizing
+HNRNPC,SBNO1,0.11222609373815734,destabilizing
+HNRNPC,RIMS2,0.14352784778883254,destabilizing
+HNRNPC,IGF1R,0.058826569690383426,destabilizing
+HNRNPC,TRIO,0.060964415537254235,destabilizing
+HNRNPC,KCND2,0.0795222070745369,destabilizing
+HNRNPC,BTBD9,0.1845236907939737,destabilizing
+HNRNPC,CNGB1,0.19879493780862342,destabilizing
+HNRNPC,FMN2,0.1596331369991081,destabilizing
+HNRNPC,ENSG00000228222,0.3060355064675134,destabilizing
+HNRNPC,ATXN1,0.06494011091200377,destabilizing
+HNRNPC,SYN3,0.05659001912212223,destabilizing
+HNRNPC,PRKN,0.2172186713074405,destabilizing
+HNRNPC,RASA2,0.24137567516524847,destabilizing
+HNRNPC,PPP1R12B,0.15289076489119366,destabilizing
+HNRNPC,FRMD4A,0.14084930207956206,destabilizing
+HNRNPC,SEMA6D,0.1800397921611351,destabilizing
+HNRNPC,WIPF2,0.2067014775503558,destabilizing
+HNRNPC,DLEU1,0.25076466527610386,destabilizing
+HNRNPC,TSHZ2,0.11584441348569009,destabilizing
+HNRNPC,MED13L,0.13742267165638913,destabilizing
+HNRNPC,AFF3,0.06209284484340786,destabilizing
+HNRNPC,KAZN,0.16005055414271802,destabilizing
+HNRNPC,KANSL1,0.12452404892707815,destabilizing
+HNRNPC,FRMD5,0.13871033076192602,destabilizing
+HNRNPC,LINC00174,0.19793683558096925,destabilizing
+HNRNPC,PPM1E,0.15043221331859855,destabilizing
+HNRNPC,ARL3,0.15544616180706436,destabilizing
+HNRNPC,MBD5,0.15462158864087588,destabilizing
+HNRNPC,ELAVL3,0.16640645729402165,destabilizing
+HNRNPC,SLIT2,0.20916489241000397,destabilizing
+HNRNPC,SLC8A1,0.06635032906598218,destabilizing
+HNRNPC,CLASP1,0.11891610844911842,destabilizing
+HNRNPC,DOCK4,0.05142896379272997,destabilizing
+HNRNPC,UNC5C,0.18606874227965622,destabilizing
+HNRNPC,CACNA2D3,-0.05735003396268509,stabilizing
+HNRNPC,RC3H1,0.10422540485770054,destabilizing
+HNRNPC,NEGR1,0.19722175230708136,destabilizing
+HNRNPC,ENOX1,0.2810534863198196,destabilizing
+HNRNPC,SCUBE1,0.11099250142496032,destabilizing
+HNRNPC,GPHN,0.1300766287967573,destabilizing
+HNRNPC,NAV3,0.1855628830142362,destabilizing
+HNRNPC,EBF1,0.08055489417424949,destabilizing
+HNRNPC,TOMM22,0.22613959257198837,destabilizing
+HNRNPC,MBNL2,0.07453723155951068,destabilizing
+HNRNPC,ANKFN1,0.07943711664316398,destabilizing
+HNRNPC,MAGI2,0.07510963123002581,destabilizing
+HNRNPC,LSAMP,0.13514065941615636,destabilizing
+HNRNPC,AKAP6,0.17629290131172365,destabilizing
+HNRNPC,TMED2,0.1599302855656624,destabilizing
+HNRNPC,ZBTB20,0.17675032451377246,destabilizing
+HNRNPC,GRIK2,0.1681470479827067,destabilizing
+HNRNPC,SOX5,0.12101183315191223,destabilizing
+HNRNPC,LRRC37A3,0.2655676515007118,destabilizing
+HNRNPC,TMEM132C,0.07748621125102,destabilizing
+HNRNPC,EYS,0.1338522409458726,destabilizing
+HNRNPC,ARID1B,0.12883408900252744,destabilizing
+HNRNPC,PRKCE,0.12448472921512982,destabilizing
+HNRNPC,RBFOX1,-0.08012276208286355,stabilizing
+HNRNPC,SDK1,0.09690918359327597,destabilizing
+HNRNPC,NRG1,0.08341302442087162,destabilizing
+HNRNPC,MLLT3,0.28792742859843906,destabilizing
+HNRNPC,FMN1,0.07211426502009409,destabilizing
+HNRNPC,ADGRB3,0.11087107733777096,destabilizing
+HNRNPC,ROBO1,0.14451125310075402,destabilizing
+HNRNPC,SYPL1,0.12604681917059202,destabilizing
+HNRNPC,PTPRD,0.1564005987655075,destabilizing
+HNRNPC,FAM155A,0.1885427709049661,destabilizing
+HNRNPC,LARP1B,0.1808745887915809,destabilizing
+HNRNPD,TRERF1,0.1806701037614353,destabilizing
+HNRNPD,SORCS1,0.09105972109414646,destabilizing
+HNRNPD,FCHSD2,0.075174993222673,destabilizing
+HNRNPD,PDE3A,0.1403092219599431,destabilizing
+HNRNPD,UNC79,0.15908748699800782,destabilizing
+HNRNPD,DOC2B,0.1211022303590425,destabilizing
+HNRNPD,TMTC2,0.1708402761423718,destabilizing
+HNRNPD,KALRN,0.10967437179508194,destabilizing
+HNRNPD,CHD1,0.08324112390202999,destabilizing
+HNRNPD,UBE2E2,0.07234841922794864,destabilizing
+HNRNPD,PPARD,0.10429986730000596,destabilizing
+HNRNPD,TOX,0.09544612348074377,destabilizing
+HNRNPD,BRAF,0.07167244406240823,destabilizing
+HNRNPD,RYR2,0.2103955509347638,destabilizing
+HNRNPD,MTMR7,0.18971691643433186,destabilizing
+HNRNPD,EIF4E,0.24752042828965698,destabilizing
+HNRNPD,SOX11,0.06369304726098671,destabilizing
+HNRNPD,EPB41L4B,0.07484508503274304,destabilizing
+HNRNPD,CACNA1B,0.10888106791813244,destabilizing
+HNRNPD,LRRTM4,0.07964636132004764,destabilizing
+HNRNPD,PTEN,0.09655412146195576,destabilizing
+HNRNPD,FRY,0.21262443969474595,destabilizing
+HNRNPD,RUNX1T1,0.06790104873480507,destabilizing
+HNRNPD,MACROD2,0.171489572348535,destabilizing
+HNRNPD,SHANK2,0.15953479236810858,destabilizing
+HNRNPD,CDK12,0.23269032114067767,destabilizing
+HNRNPD,RFX7,0.16386942837378474,destabilizing
+HNRNPD,UBR5,0.06952968857859862,destabilizing
+HNRNPD,JARID2,0.09059693834433219,destabilizing
+HNRNPD,MPHOSPH8,0.16572413277986384,destabilizing
+HNRNPD,DIP2C,0.1216491938767006,destabilizing
+HNRNPD,ZNF423,0.06185009363793958,destabilizing
+HNRNPD,UBR3,0.10018094618982334,destabilizing
+HNRNPD,DLG2,0.11166354398656697,destabilizing
+HNRNPD,CHST12,0.25506420921086165,destabilizing
+HNRNPD,EML5,0.1750638506720888,destabilizing
+HNRNPD,CENPP,0.35157860994390744,destabilizing
+HNRNPD,PSME4,0.13576007661458087,destabilizing
+HNRNPD,TMEM106B,0.1395468412477547,destabilizing
+HNRNPD,EPHA5,0.10622101489063028,destabilizing
+HNRNPD,KCNB2,0.25148013410808717,destabilizing
+HNRNPD,ZNF83,0.1440030348095484,destabilizing
+HNRNPD,SOX6,0.13575187263895608,destabilizing
+HNRNPD,ZNF521,0.14906554947362327,destabilizing
+HNRNPD,PLEKHA5,0.09217498762284349,destabilizing
+HNRNPD,NOVA1,0.1931032470109805,destabilizing
+HNRNPD,CCNY,0.15201716030931495,destabilizing
+HNRNPD,ARIH1,0.12199056528840364,destabilizing
+HNRNPD,EPB41L5,0.10861576831342047,destabilizing
+HNRNPD,GPR158,0.14345060525172956,destabilizing
+HNRNPD,NCOA2,0.07717126937063588,destabilizing
+HNRNPD,ALK,0.30031504093267664,destabilizing
+HNRNPD,IFT172,0.14481625148487295,destabilizing
+HNRNPD,CCNT1,0.10114512848193634,destabilizing
+HNRNPD,DTWD2,0.25129559142040264,destabilizing
+HNRNPD,SIK3,0.1312179778656311,destabilizing
+HNRNPD,CPEB3,0.18308110301954997,destabilizing
+HNRNPD,CADM2,0.07218384149602439,destabilizing
+HNRNPD,XKR6,0.1814988593122154,destabilizing
+HNRNPD,CADPS,0.10530950379559877,destabilizing
+HNRNPD,FGF13,0.06970176749211839,destabilizing
+HNRNPD,TCF20,0.12306630704782562,destabilizing
+HNRNPD,CDKAL1,0.11338147913948977,destabilizing
+HNRNPD,DGKI,0.1382327104389376,destabilizing
+HNRNPD,EXOC6B,0.18143511868774617,destabilizing
+HNRNPD,MAGI3,0.1651629186133529,destabilizing
+HNRNPD,SBF2,0.09970657804187448,destabilizing
+HNRNPD,INPP4B,0.0933056048041366,destabilizing
+HNRNPD,PTPRS,0.15424933924989953,destabilizing
+HNRNPD,CBFA2T2,0.057977426827542526,destabilizing
+HNRNPD,SPDYE3,0.08569501789808105,destabilizing
+HNRNPD,TMEM178B,0.0697517527583941,destabilizing
+HNRNPD,DMD,0.23223170876648616,destabilizing
+HNRNPD,EIF4G3,0.06380662512311666,destabilizing
+HNRNPD,MCU,0.1550186212697415,destabilizing
+HNRNPD,SSH2,0.12624132480055955,destabilizing
+HNRNPD,DOCK3,0.19290778138433073,destabilizing
+HNRNPD,HS6ST3,0.0927100467409405,destabilizing
+HNRNPD,LPP,0.13337988183671298,destabilizing
+HNRNPD,STAG1,0.12960670945169087,destabilizing
+HNRNPD,CAPZA2,0.16659368345660963,destabilizing
+HNRNPD,ADGRL3,0.0769215545915595,destabilizing
+HNRNPD,PHACTR1,0.09646517678542471,destabilizing
+HNRNPD,UBE2R2,0.1362232559470319,destabilizing
+HNRNPD,GTF2IRD1,0.10085021933104928,destabilizing
+HNRNPD,TTC28,0.12800508886405082,destabilizing
+HNRNPD,SBNO1,0.07221001354004838,destabilizing
+HNRNPD,RIMS2,0.10939615008510654,destabilizing
+HNRNPD,BTBD9,0.11084247261406063,destabilizing
+HNRNPD,CNGB1,0.13731482200525932,destabilizing
+HNRNPD,FMN2,0.1081379916266771,destabilizing
+HNRNPD,ENSG00000228222,0.18854610128764315,destabilizing
+HNRNPD,ATXN1,0.057824434598588006,destabilizing
+HNRNPD,SYN3,0.08405282888816727,destabilizing
+HNRNPD,PRKN,0.12498017886146631,destabilizing
+HNRNPD,RASA2,0.18630791246636944,destabilizing
+HNRNPD,PPP1R12B,0.08523153450023811,destabilizing
+HNRNPD,FRMD4A,0.0883380015887638,destabilizing
+HNRNPD,CAMK1D,0.06090756453754051,destabilizing
+HNRNPD,SEMA6D,0.13458392189214147,destabilizing
+HNRNPD,WIPF2,0.15616436051869914,destabilizing
+HNRNPD,DLEU1,0.182456758671819,destabilizing
+HNRNPD,TSHZ2,0.09578600371616819,destabilizing
+HNRNPD,MED13L,0.07416394458660909,destabilizing
+HNRNPD,KAZN,0.1109734714649752,destabilizing
+HNRNPD,KANSL1,0.0674875935812786,destabilizing
+HNRNPD,FRMD5,0.12914981826207064,destabilizing
+HNRNPD,LINC00174,0.15770406398714298,destabilizing
+HNRNPD,PPM1E,0.0879648417135251,destabilizing
+HNRNPD,ARL3,0.12495034621548043,destabilizing
+HNRNPD,MBD5,0.1131643627973004,destabilizing
+HNRNPD,ELAVL3,0.14343698465426447,destabilizing
+HNRNPD,SLIT2,0.13725186224662056,destabilizing
+HNRNPD,CLASP1,0.11813386190734092,destabilizing
+HNRNPD,UNC5C,0.14482182879352662,destabilizing
+HNRNPD,NEGR1,0.1815474607908587,destabilizing
+HNRNPD,ENOX1,0.19948496304542013,destabilizing
+HNRNPD,GPHN,0.09371254394552006,destabilizing
+HNRNPD,NAV3,0.13402523777050457,destabilizing
+HNRNPD,EBF1,0.06472796014367235,destabilizing
+HNRNPD,TOMM22,0.16430343688765203,destabilizing
+HNRNPD,ANKFN1,0.08339765019239388,destabilizing
+HNRNPD,MAGI2,0.06798522417653453,destabilizing
+HNRNPD,LSAMP,0.0981128033212974,destabilizing
+HNRNPD,AKAP6,0.13964219754573673,destabilizing
+HNRNPD,ZBTB20,0.13878341974160083,destabilizing
+HNRNPD,GRIK2,0.1010248564070164,destabilizing
+HNRNPD,SOX5,0.07865421822762825,destabilizing
+HNRNPD,LRRC37A3,0.18619915536857368,destabilizing
+HNRNPD,TMEM132C,0.05203913002548147,destabilizing
+HNRNPD,EYS,0.10707304519590927,destabilizing
+HNRNPD,ARID1B,0.08541830511131002,destabilizing
+HNRNPD,RBFOX1,-0.08386483143407142,stabilizing
+HNRNPD,SDK1,0.06496222023691274,destabilizing
+HNRNPD,MLLT3,0.23744332286067996,destabilizing
+HNRNPD,FMN1,0.06250162102544475,destabilizing
+HNRNPD,ADGRB3,0.09309139170117606,destabilizing
+HNRNPD,ROBO1,0.0872313233192264,destabilizing
+HNRNPD,SYPL1,0.10161711819620811,destabilizing
+HNRNPD,PTPRD,0.1270352102414079,destabilizing
+HNRNPD,FAM155A,0.15620483273366512,destabilizing
+HNRNPD,LARP1B,0.12585011919084185,destabilizing
+HNRNPF,TRERF1,0.13298883645378934,destabilizing
+HNRNPF,SORCS1,0.08728816219346798,destabilizing
+HNRNPF,NCOA1,0.058975821378284124,destabilizing
+HNRNPF,COPA,0.06262724497256379,destabilizing
+HNRNPF,FCHSD2,0.06499944308867557,destabilizing
+HNRNPF,PDE3A,0.11272613772774216,destabilizing
+HNRNPF,UNC79,0.1419498495597709,destabilizing
+HNRNPF,DOC2B,0.1066215804687667,destabilizing
+HNRNPF,TMTC2,0.16408701101427942,destabilizing
+HNRNPF,KALRN,0.08678628630379413,destabilizing
+HNRNPF,CHD1,0.0805101456732948,destabilizing
+HNRNPF,UBE2E2,0.07882417776104587,destabilizing
+HNRNPF,PPARD,0.08762962026721687,destabilizing
+HNRNPF,TOX,0.07857521897367795,destabilizing
+HNRNPF,BRAF,0.0726760256990723,destabilizing
+HNRNPF,RYR2,0.15270048454416663,destabilizing
+HNRNPF,MTMR7,0.17916189801609586,destabilizing
+HNRNPF,EPB41L4B,0.07676233796210663,destabilizing
+HNRNPF,CACNA1B,0.09968316039605005,destabilizing
+HNRNPF,LRRTM4,0.09015205716912068,destabilizing
+HNRNPF,SIRPA,0.09998741521772586,destabilizing
+HNRNPF,FRY,0.14995646975594676,destabilizing
+HNRNPF,RUNX1T1,0.06544776450805345,destabilizing
+HNRNPF,MACROD2,0.14370794772158796,destabilizing
+HNRNPF,SHANK2,0.15573836157793985,destabilizing
+HNRNPF,CDK12,0.19333449100865133,destabilizing
+HNRNPF,RFX7,0.12657003599024494,destabilizing
+HNRNPF,JARID2,0.06316615704740416,destabilizing
+HNRNPF,MPHOSPH8,0.12576151349305728,destabilizing
+HNRNPF,DIP2C,0.08343187861739716,destabilizing
+HNRNPF,MGAT5,0.05234019200990349,destabilizing
+HNRNPF,DLG2,0.1096587995231129,destabilizing
+HNRNPF,CHST12,0.20324149497475805,destabilizing
+HNRNPF,EML5,0.1550374800164195,destabilizing
+HNRNPF,CENPP,0.24221304759728335,destabilizing
+HNRNPF,PSME4,0.13830448195655728,destabilizing
+HNRNPF,TMEM106B,0.1456547883958764,destabilizing
+HNRNPF,EPHA5,0.1348496052528239,destabilizing
+HNRNPF,KCNB2,0.15440546615013,destabilizing
+HNRNPF,ZNF83,0.10298867907633033,destabilizing
+HNRNPF,SOX6,0.09305927360123963,destabilizing
+HNRNPF,ZNF521,0.0978426247479185,destabilizing
+HNRNPF,PLEKHA5,0.08355421978072673,destabilizing
+HNRNPF,NOVA1,0.1447373648354119,destabilizing
+HNRNPF,CCNY,0.1318828969031873,destabilizing
+HNRNPF,ARIH1,0.10839135282009042,destabilizing
+HNRNPF,EPB41L5,0.07882021575869341,destabilizing
+HNRNPF,GPR158,0.12516345034188645,destabilizing
+HNRNPF,NCOA2,0.08811530535630482,destabilizing
+HNRNPF,ALK,0.20650543992418066,destabilizing
+HNRNPF,CTNND2,0.05598549370974546,destabilizing
+HNRNPF,IFT172,0.14850512029113538,destabilizing
+HNRNPF,CCNT1,0.08551894192592815,destabilizing
+HNRNPF,DTWD2,0.2118766834878109,destabilizing
+HNRNPF,SIK3,0.11111881651456082,destabilizing
+HNRNPF,CPEB3,0.15960306339324953,destabilizing
+HNRNPF,CADM2,0.06502661013318803,destabilizing
+HNRNPF,XKR6,0.13454877602446427,destabilizing
+HNRNPF,CADPS,0.07291171790562338,destabilizing
+HNRNPF,TCF20,0.12950144346185807,destabilizing
+HNRNPF,CDKAL1,0.08633574448077617,destabilizing
+HNRNPF,DGKI,0.11586527406708604,destabilizing
+HNRNPF,EXOC6B,0.1808486376355466,destabilizing
+HNRNPF,MAGI3,0.14973421921643548,destabilizing
+HNRNPF,SBF2,0.06896226966297177,destabilizing
+HNRNPF,INPP4B,0.08340182129264805,destabilizing
+HNRNPF,PTPRS,0.12202911616837088,destabilizing
+HNRNPF,CBFA2T2,0.055961654606707115,destabilizing
+HNRNPF,SPDYE3,0.11454542907548904,destabilizing
+HNRNPF,TMEM178B,0.06254965670135004,destabilizing
+HNRNPF,DMD,0.17712147162865494,destabilizing
+HNRNPF,MCU,0.11644092841388697,destabilizing
+HNRNPF,SSH2,0.1147039400509405,destabilizing
+HNRNPF,DOCK3,0.16799284161552228,destabilizing
+HNRNPF,HS6ST3,0.11387140923517858,destabilizing
+HNRNPF,LPP,0.11535067832543262,destabilizing
+HNRNPF,STAG1,0.11493779723586177,destabilizing
+HNRNPF,CAPZA2,0.13266876270931477,destabilizing
+HNRNPF,ADGRL3,0.06161428514765191,destabilizing
+HNRNPF,PHACTR1,0.0842147880763383,destabilizing
+HNRNPF,UBE2R2,0.1152561166115015,destabilizing
+HNRNPF,GTF2IRD1,0.08410545605184787,destabilizing
+HNRNPF,CCBE1,0.05560108710795591,destabilizing
+HNRNPF,TTC28,0.09296009854776412,destabilizing
+HNRNPF,RIMS2,0.10032575500850836,destabilizing
+HNRNPF,IGF1R,0.05474695995298173,destabilizing
+HNRNPF,BTBD9,0.12414689915234581,destabilizing
+HNRNPF,CNGB1,0.11746879519280612,destabilizing
+HNRNPF,FMN2,0.10924785173897479,destabilizing
+HNRNPF,ENSG00000228222,0.21975678524724326,destabilizing
+HNRNPF,SYN3,0.06590660827033887,destabilizing
+HNRNPF,PRKN,0.1050510374140874,destabilizing
+HNRNPF,RASA2,0.1377656590681576,destabilizing
+HNRNPF,PPP1R12B,0.10351386168851007,destabilizing
+HNRNPF,FRMD4A,0.11529752260586149,destabilizing
+HNRNPF,CAMK1D,0.060478735543318944,destabilizing
+HNRNPF,SEMA6D,0.11055258203732589,destabilizing
+HNRNPF,WIPF2,0.1434875518095493,destabilizing
+HNRNPF,DLEU1,0.20752230435952682,destabilizing
+HNRNPF,TSHZ2,0.08472284268207562,destabilizing
+HNRNPF,KAZN,0.08458202614994335,destabilizing
+HNRNPF,KANSL1,0.0986503350315507,destabilizing
+HNRNPF,FRMD5,0.12449583610594597,destabilizing
+HNRNPF,LINC00174,0.11463308458205204,destabilizing
+HNRNPF,PPM1E,0.0990874800191819,destabilizing
+HNRNPF,ARL3,0.09501028992723803,destabilizing
+HNRNPF,MBD5,0.10352028713271134,destabilizing
+HNRNPF,ELAVL3,0.10867944572317219,destabilizing
+HNRNPF,SLIT2,0.16919728900674808,destabilizing
+HNRNPF,CLASP1,0.11373545233990943,destabilizing
+HNRNPF,UNC5C,0.12363614437870912,destabilizing
+HNRNPF,CACNA2D3,-0.05214600512347681,stabilizing
+HNRNPF,RC3H1,0.07399402609927398,destabilizing
+HNRNPF,NEGR1,0.1314259058782848,destabilizing
+HNRNPF,ENOX1,0.15508121076496964,destabilizing
+HNRNPF,GPHN,0.09443029263270877,destabilizing
+HNRNPF,NAV3,0.141700273398321,destabilizing
+HNRNPF,TOMM22,0.11241495915817377,destabilizing
+HNRNPF,ANKFN1,0.05707571399446222,destabilizing
+HNRNPF,MAGI2,0.05539560277842859,destabilizing
+HNRNPF,LSAMP,0.09107507581101412,destabilizing
+HNRNPF,AKAP6,0.1348929796472077,destabilizing
+HNRNPF,TMED2,0.10596706964388898,destabilizing
+HNRNPF,ZBTB20,0.12083994781519923,destabilizing
+HNRNPF,GRIK2,0.10880870187975972,destabilizing
+HNRNPF,SOX5,0.08788235406020568,destabilizing
+HNRNPF,LRRC37A3,0.16792608255432886,destabilizing
+HNRNPF,EYS,0.085326299851273,destabilizing
+HNRNPF,ARID1B,0.07805577422995819,destabilizing
+HNRNPF,PRKCE,0.09315091090264462,destabilizing
+HNRNPF,RBFOX1,-0.07236873410191941,stabilizing
+HNRNPF,SDK1,0.06579766005912682,destabilizing
+HNRNPF,NRG1,0.05423022286269809,destabilizing
+HNRNPF,MLLT3,0.17987390833877065,destabilizing
+HNRNPF,FMN1,0.08839780650869913,destabilizing
+HNRNPF,ADGRB3,0.0767170173288868,destabilizing
+HNRNPF,ROBO1,0.08277783461801945,destabilizing
+HNRNPF,SYPL1,0.08741007713931692,destabilizing
+HNRNPF,PTPRD,0.101401575476632,destabilizing
+HNRNPF,FAM155A,0.13814431361327306,destabilizing
+HNRNPF,LARP1B,0.1280482224453025,destabilizing
+HNRNPH1,SORCS1,0.07145949408476807,destabilizing
+HNRNPH1,UNC79,0.07935446486736979,destabilizing
+HNRNPH1,MACROD2,0.07155088785163917,destabilizing
+HNRNPH1,SHANK2,0.11670820918269116,destabilizing
+HNRNPH1,KCNB2,0.1047094907428536,destabilizing
+HNRNPH1,EXOC6B,0.09541826300618952,destabilizing
+HNRNPH1,MAGI3,0.07919302431573565,destabilizing
+HNRNPH1,DMD,0.07921177022053769,destabilizing
+HNRNPH1,GTF2IRD1,0.06655435193864509,destabilizing
+HNRNPH1,WIPF2,0.07798705506138875,destabilizing
+HNRNPH1,FRMD5,0.07326509548061458,destabilizing
+HNRNPH1,SLIT2,0.08679744433386062,destabilizing
+HNRNPH1,LRRC37A3,0.07916422745144308,destabilizing
+HNRNPH1,EYS,0.05434529728555894,destabilizing
+HNRNPH1,RBFOX1,-0.06490199365265828,stabilizing
+HNRNPK,TRERF1,0.19831411597288126,destabilizing
+HNRNPK,SORCS1,0.09891835322316737,destabilizing
+HNRNPK,COPA,0.07845256314791432,destabilizing
+HNRNPK,FCHSD2,0.08455372429513547,destabilizing
+HNRNPK,PDE3A,0.15547927932295968,destabilizing
+HNRNPK,UNC79,0.1669210802264425,destabilizing
+HNRNPK,DOC2B,0.13567624844941867,destabilizing
+HNRNPK,TMTC2,0.1917835630050624,destabilizing
+HNRNPK,KALRN,0.12247582191715355,destabilizing
+HNRNPK,CHD1,0.07084201318640398,destabilizing
+HNRNPK,UBE2E2,0.0627521390467147,destabilizing
+HNRNPK,PPARD,0.09124591952986313,destabilizing
+HNRNPK,TOX,0.0915731247290727,destabilizing
+HNRNPK,BRAF,0.05837198543656205,destabilizing
+HNRNPK,RYR2,0.1836398727620074,destabilizing
+HNRNPK,MTMR7,0.20144516177299934,destabilizing
+HNRNPK,EIF4E,0.2366732574467138,destabilizing
+HNRNPK,SOX11,0.06632092022647887,destabilizing
+HNRNPK,EPB41L4B,0.08373146829980667,destabilizing
+HNRNPK,CACNA1B,0.1275098093949301,destabilizing
+HNRNPK,TBC1D5,0.0667381421087806,destabilizing
+HNRNPK,WSB1,0.05241493628284217,destabilizing
+HNRNPK,LRRTM4,0.0820212905769425,destabilizing
+HNRNPK,PTEN,0.12428389331550004,destabilizing
+HNRNPK,FRY,0.20647548811409913,destabilizing
+HNRNPK,RUNX1T1,0.07857418565876217,destabilizing
+HNRNPK,MACROD2,0.1648262542081091,destabilizing
+HNRNPK,SHANK2,0.19914108395265412,destabilizing
+HNRNPK,CDK12,0.267578593969612,destabilizing
+HNRNPK,RFX7,0.17297896981676442,destabilizing
+HNRNPK,UBR5,0.06324226151429724,destabilizing
+HNRNPK,JARID2,0.08026772270411092,destabilizing
+HNRNPK,MPHOSPH8,0.19094677919879446,destabilizing
+HNRNPK,DIP2C,0.09955910931965574,destabilizing
+HNRNPK,UBR3,0.09528542767103364,destabilizing
+HNRNPK,DLG2,0.11095336299050663,destabilizing
+HNRNPK,CHST12,0.29818916910818855,destabilizing
+HNRNPK,EML5,0.16957792918300604,destabilizing
+HNRNPK,CENPP,0.2949071549468914,destabilizing
+HNRNPK,PSME4,0.12095894128996787,destabilizing
+HNRNPK,TMEM106B,0.16795952449634832,destabilizing
+HNRNPK,EPHA5,0.1305688791997858,destabilizing
+HNRNPK,KCNB2,0.25517307079642726,destabilizing
+HNRNPK,ZNF83,0.15752213442953406,destabilizing
+HNRNPK,SOX6,0.13333231329109677,destabilizing
+HNRNPK,ZNF521,0.17316873837972505,destabilizing
+HNRNPK,PLEKHA5,0.10423886679968618,destabilizing
+HNRNPK,NOVA1,0.21939604062083662,destabilizing
+HNRNPK,CCNY,0.15981618177712287,destabilizing
+HNRNPK,ARIH1,0.10769849710386069,destabilizing
+HNRNPK,EPB41L5,0.10068321038438084,destabilizing
+HNRNPK,GPR158,0.1389766839674793,destabilizing
+HNRNPK,NCOA2,0.09521574716042487,destabilizing
+HNRNPK,MARCKS,0.09828993034467408,destabilizing
+HNRNPK,ALK,0.2781127541456192,destabilizing
+HNRNPK,ACACA,0.05920510428863448,destabilizing
+HNRNPK,IFT172,0.1742560725861521,destabilizing
+HNRNPK,CCNT1,0.12583124763851894,destabilizing
+HNRNPK,DTWD2,0.307585672813,destabilizing
+HNRNPK,SIK3,0.12500905418069982,destabilizing
+HNRNPK,CPEB3,0.21763960812295222,destabilizing
+HNRNPK,CADM2,0.07836070899939786,destabilizing
+HNRNPK,XKR6,0.21016724485506616,destabilizing
+HNRNPK,RMND5A,0.06873527754610442,destabilizing
+HNRNPK,CADPS,0.10889138791023872,destabilizing
+HNRNPK,FGF13,0.07926461185215161,destabilizing
+HNRNPK,TCF20,0.13225745732818192,destabilizing
+HNRNPK,CDKAL1,0.10597948806559904,destabilizing
+HNRNPK,DGKI,0.1339359654005452,destabilizing
+HNRNPK,EXOC6B,0.20305459187679942,destabilizing
+HNRNPK,MAGI3,0.1809207183779179,destabilizing
+HNRNPK,SBF2,0.09960396755184898,destabilizing
+HNRNPK,INPP4B,0.127601671831602,destabilizing
+HNRNPK,PTPRS,0.177453573234624,destabilizing
+HNRNPK,CBFA2T2,0.07372203072959875,destabilizing
+HNRNPK,SPDYE3,0.10879994293600481,destabilizing
+HNRNPK,TMEM178B,0.07687026642462802,destabilizing
+HNRNPK,DMD,0.23393582597900714,destabilizing
+HNRNPK,EIF4G3,0.07555933882283132,destabilizing
+HNRNPK,MCU,0.10283278301286773,destabilizing
+HNRNPK,SSH2,0.1293329938909729,destabilizing
+HNRNPK,DOCK3,0.19075747457183875,destabilizing
+HNRNPK,HS6ST3,0.11118495840517735,destabilizing
+HNRNPK,LPP,0.1280444044275936,destabilizing
+HNRNPK,STAG1,0.13221934614809563,destabilizing
+HNRNPK,CAPZA2,0.18614935495269494,destabilizing
+HNRNPK,ADGRL3,0.06856145886632811,destabilizing
+HNRNPK,PHACTR1,0.11551295904808358,destabilizing
+HNRNPK,UBE2R2,0.1719560690294296,destabilizing
+HNRNPK,GTF2IRD1,0.09605863690487529,destabilizing
+HNRNPK,VAPA,0.06504999067336227,destabilizing
+HNRNPK,JMJD1C,0.07800378577423162,destabilizing
+HNRNPK,TTC28,0.13106098852861556,destabilizing
+HNRNPK,SBNO1,0.07838995770895653,destabilizing
+HNRNPK,RIMS2,0.11167596607149749,destabilizing
+HNRNPK,BTBD9,0.11290580620974278,destabilizing
+HNRNPK,CNGB1,0.168993045161157,destabilizing
+HNRNPK,FMN2,0.1030162434203527,destabilizing
+HNRNPK,ENSG00000228222,0.26823210392086666,destabilizing
+HNRNPK,SYN3,0.08707822307550125,destabilizing
+HNRNPK,PRKN,0.13840485983609138,destabilizing
+HNRNPK,RASA2,0.21020536900769363,destabilizing
+HNRNPK,PPP1R12B,0.10846375113366004,destabilizing
+HNRNPK,FRMD4A,0.11030906244190557,destabilizing
+HNRNPK,SEMA6D,0.14249666664691737,destabilizing
+HNRNPK,WIPF2,0.18548619650096348,destabilizing
+HNRNPK,DLEU1,0.2280950936662628,destabilizing
+HNRNPK,TSHZ2,0.09621365601607099,destabilizing
+HNRNPK,MED13L,0.08289171286847147,destabilizing
+HNRNPK,KAZN,0.10914271458165123,destabilizing
+HNRNPK,KANSL1,0.08946998715816332,destabilizing
+HNRNPK,FRMD5,0.13598756019900637,destabilizing
+HNRNPK,LINC00174,0.2088013188316561,destabilizing
+HNRNPK,PPM1E,0.11433040506263867,destabilizing
+HNRNPK,ARL3,0.15279561108120307,destabilizing
+HNRNPK,MBD5,0.14757678295747212,destabilizing
+HNRNPK,ELAVL3,0.17671522310204915,destabilizing
+HNRNPK,SLIT2,0.17886294036234632,destabilizing
+HNRNPK,CLASP1,0.10922412029917734,destabilizing
+HNRNPK,UNC5C,0.1667420056756561,destabilizing
+HNRNPK,RC3H1,0.0818186956784302,destabilizing
+HNRNPK,NEGR1,0.19010680957433454,destabilizing
+HNRNPK,ENOX1,0.22035700791071786,destabilizing
+HNRNPK,SCUBE1,0.10635841435459192,destabilizing
+HNRNPK,GPHN,0.08399413845913702,destabilizing
+HNRNPK,NAV3,0.15437414002382333,destabilizing
+HNRNPK,EBF1,0.056867238073743304,destabilizing
+HNRNPK,TOMM22,0.21335896749884561,destabilizing
+HNRNPK,MBNL2,0.054690843574211986,destabilizing
+HNRNPK,ANKFN1,0.08677280099002707,destabilizing
+HNRNPK,MAGI2,0.062086506754071145,destabilizing
+HNRNPK,LSAMP,0.1131291329771985,destabilizing
+HNRNPK,AKAP6,0.1339447885154207,destabilizing
+HNRNPK,TMED2,0.15823361850136516,destabilizing
+HNRNPK,ZBTB20,0.14599716944654442,destabilizing
+HNRNPK,GRIK2,0.11860344900683499,destabilizing
+HNRNPK,SOX5,0.09995891456271767,destabilizing
+HNRNPK,LRRC37A3,0.216979450955858,destabilizing
+HNRNPK,TMEM132C,0.05746920933725517,destabilizing
+HNRNPK,EYS,0.12359885089206117,destabilizing
+HNRNPK,ARID1B,0.07632444395158001,destabilizing
+HNRNPK,PRKCE,0.08027517878425851,destabilizing
+HNRNPK,RBFOX1,-0.0718540462651609,stabilizing
+HNRNPK,SDK1,0.06500804257360845,destabilizing
+HNRNPK,NRG1,0.07349642629170965,destabilizing
+HNRNPK,RORA,0.07709055943832997,destabilizing
+HNRNPK,MLLT3,0.28925766081138593,destabilizing
+HNRNPK,ROBO1,0.07522811760258148,destabilizing
+HNRNPK,SYPL1,0.1093073932632251,destabilizing
+HNRNPK,PTPRD,0.15373587679530967,destabilizing
+HNRNPK,FAM155A,0.18275073552933915,destabilizing
+HNRNPK,LARP1B,0.11782546455845289,destabilizing
+HNRNPL,CDK12,0.09400475937175365,destabilizing
+HNRNPL,MLLT3,0.0963383037194568,destabilizing
+HNRNPM,TRERF1,0.1115983182329272,destabilizing
+HNRNPM,SORCS1,0.06425337026569863,destabilizing
+HNRNPM,PDE3A,0.1049101919939698,destabilizing
+HNRNPM,UNC79,0.13411233603224199,destabilizing
+HNRNPM,DOC2B,0.08685252903058786,destabilizing
+HNRNPM,TMTC2,0.1117834104237227,destabilizing
+HNRNPM,KALRN,0.0795843013958462,destabilizing
+HNRNPM,UBE2E2,0.061861760128170296,destabilizing
+HNRNPM,BRAF,0.0518561961232194,destabilizing
+HNRNPM,RYR2,0.12656378254678843,destabilizing
+HNRNPM,MTMR7,0.1359386258877664,destabilizing
+HNRNPM,EIF4E,0.13313235047220692,destabilizing
+HNRNPM,CACNA1B,0.07672598472844773,destabilizing
+HNRNPM,LRRTM4,0.06742525163252612,destabilizing
+HNRNPM,PTEN,0.08375218573481667,destabilizing
+HNRNPM,FRY,0.13583116785803842,destabilizing
+HNRNPM,RUNX1T1,0.06388584012981013,destabilizing
+HNRNPM,MACROD2,0.10830939230726291,destabilizing
+HNRNPM,SHANK2,0.11988373532315634,destabilizing
+HNRNPM,CDK12,0.1813283395616649,destabilizing
+HNRNPM,RFX7,0.11797741267389576,destabilizing
+HNRNPM,MPHOSPH8,0.13157071397344322,destabilizing
+HNRNPM,DLG2,0.08388626292940171,destabilizing
+HNRNPM,CHST12,0.1957794313846208,destabilizing
+HNRNPM,EML5,0.0874838201095245,destabilizing
+HNRNPM,CENPP,0.2669635728896386,destabilizing
+HNRNPM,PSME4,0.07537458126901607,destabilizing
+HNRNPM,TMEM106B,0.0940806627891351,destabilizing
+HNRNPM,EPHA5,0.08784985659966811,destabilizing
+HNRNPM,KCNB2,0.16166579931512706,destabilizing
+HNRNPM,SOX6,0.08220306390773849,destabilizing
+HNRNPM,ZNF521,0.1339679304545678,destabilizing
+HNRNPM,PLEKHA5,0.07492758210428878,destabilizing
+HNRNPM,NOVA1,0.15446538118330658,destabilizing
+HNRNPM,CCNY,0.12226558196434226,destabilizing
+HNRNPM,ARIH1,0.07398731373480162,destabilizing
+HNRNPM,EPB41L5,0.05822479850277335,destabilizing
+HNRNPM,GPR158,0.08913800694117566,destabilizing
+HNRNPM,NCOA2,0.06523172799684597,destabilizing
+HNRNPM,MARCKS,0.05462107148023628,destabilizing
+HNRNPM,ALK,0.20578328317784636,destabilizing
+HNRNPM,IFT172,0.12149049732772856,destabilizing
+HNRNPM,CCNT1,0.08188512560346281,destabilizing
+HNRNPM,DTWD2,0.2304837144939883,destabilizing
+HNRNPM,CPEB3,0.1439126570028395,destabilizing
+HNRNPM,CADM2,0.06813683913172258,destabilizing
+HNRNPM,XKR6,0.12684943965579162,destabilizing
+HNRNPM,TCF20,0.0854657630803875,destabilizing
+HNRNPM,CDKAL1,0.07026482177817575,destabilizing
+HNRNPM,DGKI,0.09518980963964624,destabilizing
+HNRNPM,EXOC6B,0.1257711158075305,destabilizing
+HNRNPM,MAGI3,0.11661381885386064,destabilizing
+HNRNPM,INPP4B,0.079913351242691,destabilizing
+HNRNPM,PTPRS,0.14799705040895533,destabilizing
+HNRNPM,DMD,0.14956789990412456,destabilizing
+HNRNPM,MCU,0.07744012548788223,destabilizing
+HNRNPM,SSH2,0.10872927605853609,destabilizing
+HNRNPM,DOCK3,0.1534386993375542,destabilizing
+HNRNPM,HS6ST3,0.09053948212235824,destabilizing
+HNRNPM,STAG1,0.0723193597818627,destabilizing
+HNRNPM,CAPZA2,0.1424077275154364,destabilizing
+HNRNPM,ADGRL3,0.05940250760513097,destabilizing
+HNRNPM,PHACTR1,0.0739240540403323,destabilizing
+HNRNPM,UBE2R2,0.12365460899382426,destabilizing
+HNRNPM,GTF2IRD1,0.06836868522746653,destabilizing
+HNRNPM,TTC28,0.08751298409241016,destabilizing
+HNRNPM,RIMS2,0.09071856136393386,destabilizing
+HNRNPM,BTBD9,0.09845065491516093,destabilizing
+HNRNPM,CNGB1,0.12379786481636916,destabilizing
+HNRNPM,FMN2,0.071299546120774,destabilizing
+HNRNPM,ENSG00000228222,0.15561041119530353,destabilizing
+HNRNPM,SYN3,0.055631572821169345,destabilizing
+HNRNPM,PRKN,0.11305900625489695,destabilizing
+HNRNPM,RASA2,0.14326553205110304,destabilizing
+HNRNPM,FRMD4A,0.06418726624751839,destabilizing
+HNRNPM,SEMA6D,0.10084978077922795,destabilizing
+HNRNPM,WIPF2,0.12051674830953966,destabilizing
+HNRNPM,DLEU1,0.1443000017944373,destabilizing
+HNRNPM,TSHZ2,0.05531040595010118,destabilizing
+HNRNPM,FRMD5,0.07631900970192758,destabilizing
+HNRNPM,LINC00174,0.13590414457532524,destabilizing
+HNRNPM,ARL3,0.09592217337986099,destabilizing
+HNRNPM,MBD5,0.09021587058676804,destabilizing
+HNRNPM,ELAVL3,0.11096062183506729,destabilizing
+HNRNPM,SLIT2,0.12121088585286821,destabilizing
+HNRNPM,CLASP1,0.07575429400162086,destabilizing
+HNRNPM,UNC5C,0.09696081897572793,destabilizing
+HNRNPM,NEGR1,0.14577561365873973,destabilizing
+HNRNPM,ENOX1,0.16333293812004165,destabilizing
+HNRNPM,GPHN,0.0739229018295113,destabilizing
+HNRNPM,NAV3,0.11639954645334194,destabilizing
+HNRNPM,TOMM22,0.13208480468994882,destabilizing
+HNRNPM,ANKFN1,0.06921536445467326,destabilizing
+HNRNPM,LSAMP,0.059570056521427786,destabilizing
+HNRNPM,AKAP6,0.0668413230895684,destabilizing
+HNRNPM,TMED2,0.08929134683758203,destabilizing
+HNRNPM,ZBTB20,0.10460719695698001,destabilizing
+HNRNPM,GRIK2,0.08043386379991453,destabilizing
+HNRNPM,LRRC37A3,0.16969073838244053,destabilizing
+HNRNPM,TMEM132C,0.05555086039747214,destabilizing
+HNRNPM,EYS,0.08214888797082515,destabilizing
+HNRNPM,ARID1B,0.05719145934401087,destabilizing
+HNRNPM,RBFOX1,-0.051557743561089255,stabilizing
+HNRNPM,MLLT3,0.19278372122138285,destabilizing
+HNRNPM,SYPL1,0.07440799465409298,destabilizing
+HNRNPM,PTPRD,0.09079461966167507,destabilizing
+HNRNPM,FAM155A,0.1368479337059462,destabilizing
+HNRNPM,LARP1B,0.08580554697547846,destabilizing
+HNRNPU,TRERF1,0.11909544719780628,destabilizing
+HNRNPU,SORCS1,0.07436769107815641,destabilizing
+HNRNPU,UNC79,0.10623736830222116,destabilizing
+HNRNPU,DOC2B,0.0813886433790371,destabilizing
+HNRNPU,TMTC2,0.11192128353261174,destabilizing
+HNRNPU,TOX,0.09012659764228212,destabilizing
+HNRNPU,RYR2,0.12979941180945065,destabilizing
+HNRNPU,MTMR7,0.14196736350694508,destabilizing
+HNRNPU,EIF4E,0.14688674648406205,destabilizing
+HNRNPU,CACNA1B,0.06197953229689015,destabilizing
+HNRNPU,LRRTM4,0.061358605011787096,destabilizing
+HNRNPU,FRY,0.15164066400319168,destabilizing
+HNRNPU,MACROD2,0.11907914601922115,destabilizing
+HNRNPU,SHANK2,0.14131155241218585,destabilizing
+HNRNPU,CDK12,0.15199838705909707,destabilizing
+HNRNPU,RFX7,0.1276552173620248,destabilizing
+HNRNPU,MPHOSPH8,0.08781384093679387,destabilizing
+HNRNPU,DLG2,0.06930909563721441,destabilizing
+HNRNPU,CHST12,0.12411374722786786,destabilizing
+HNRNPU,EML5,0.10678647189488463,destabilizing
+HNRNPU,CENPP,0.25716301738930725,destabilizing
+HNRNPU,PSME4,0.08834711250824828,destabilizing
+HNRNPU,TMEM106B,0.08456164848173954,destabilizing
+HNRNPU,EPHA5,0.10335312023347965,destabilizing
+HNRNPU,KCNB2,0.15640650075560664,destabilizing
+HNRNPU,ZNF83,0.07694095598995829,destabilizing
+HNRNPU,SOX6,0.07209164257450353,destabilizing
+HNRNPU,ZNF521,0.07176760127880563,destabilizing
+HNRNPU,DTL,-0.0989350377984482,stabilizing
+HNRNPU,NOVA1,0.11148961582944823,destabilizing
+HNRNPU,CCNY,0.10030851362655506,destabilizing
+HNRNPU,ARIH1,0.07308297420235176,destabilizing
+HNRNPU,GPR158,0.11032467613379042,destabilizing
+HNRNPU,ALK,0.23844477317290755,destabilizing
+HNRNPU,IFT172,0.11720545955315112,destabilizing
+HNRNPU,CCNT1,0.05584593167509254,destabilizing
+HNRNPU,DTWD2,0.174871274542908,destabilizing
+HNRNPU,SIK3,0.1005476174739993,destabilizing
+HNRNPU,CPEB3,0.12610853252553572,destabilizing
+HNRNPU,XKR6,0.1342364508009606,destabilizing
+HNRNPU,CADPS,0.06231387511810726,destabilizing
+HNRNPU,CDKAL1,0.06526136417670456,destabilizing
+HNRNPU,DGKI,0.09749018359145162,destabilizing
+HNRNPU,EXOC6B,0.11171044720224484,destabilizing
+HNRNPU,MAGI3,0.12426734327759571,destabilizing
+HNRNPU,DMD,0.1624334657715133,destabilizing
+HNRNPU,MCU,0.08305691337483277,destabilizing
+HNRNPU,SSH2,0.08573464182265508,destabilizing
+HNRNPU,DOCK3,0.11870307669392675,destabilizing
+HNRNPU,CAPZA2,0.10992969017244927,destabilizing
+HNRNPU,PHACTR1,0.08109838268962016,destabilizing
+HNRNPU,GTF2IRD1,0.08373364017753238,destabilizing
+HNRNPU,CNGB1,0.08361172251607461,destabilizing
+HNRNPU,FMN2,0.06288968451160154,destabilizing
+HNRNPU,ENSG00000228222,0.17022456800325797,destabilizing
+HNRNPU,SYN3,0.0753651557418645,destabilizing
+HNRNPU,PRKN,0.103300674073411,destabilizing
+HNRNPU,RASA2,0.09692617789388426,destabilizing
+HNRNPU,CAMK1D,0.06090627208049326,destabilizing
+HNRNPU,SEMA6D,0.08367970409667166,destabilizing
+HNRNPU,WIPF2,0.11554967806186274,destabilizing
+HNRNPU,DLEU1,0.13369538214382387,destabilizing
+HNRNPU,TSHZ2,0.062526905888037,destabilizing
+HNRNPU,KANSL1,0.07235205460152605,destabilizing
+HNRNPU,FRMD5,0.09683025532900426,destabilizing
+HNRNPU,LINC00174,0.08413982983283338,destabilizing
+HNRNPU,ARL3,0.10087299415386129,destabilizing
+HNRNPU,MBD5,0.07154860254121051,destabilizing
+HNRNPU,ELAVL3,0.08973571366146985,destabilizing
+HNRNPU,SLIT2,0.10148945178869773,destabilizing
+HNRNPU,UNC5C,0.09390500983499321,destabilizing
+HNRNPU,NEGR1,0.11721361797886318,destabilizing
+HNRNPU,ENOX1,0.14974137471376628,destabilizing
+HNRNPU,GPHN,0.07341216788069561,destabilizing
+HNRNPU,ANKFN1,0.0565896357625958,destabilizing
+HNRNPU,AKAP6,0.06960620897019429,destabilizing
+HNRNPU,ZBTB20,0.10754592768237534,destabilizing
+HNRNPU,GRIK2,0.07412750619297073,destabilizing
+HNRNPU,LRRC37A3,0.1536134165139101,destabilizing
+HNRNPU,MLLT3,0.13751930414851984,destabilizing
+HNRNPU,SYPL1,0.0740323874867713,destabilizing
+HNRNPU,PTPRD,0.08681256664874587,destabilizing
+HNRNPU,FAM155A,0.13485395793884578,destabilizing
+HNRNPU,LARP1B,0.06198596354135521,destabilizing
+RBFOX1,TRERF1,0.1545472384595598,destabilizing
+RBFOX1,SORCS1,0.09929214769829856,destabilizing
+RBFOX1,NCOA1,0.06362544291602562,destabilizing
+RBFOX1,PDE3A,0.17659648088697377,destabilizing
+RBFOX1,UNC79,0.17759890041421114,destabilizing
+RBFOX1,DOC2B,0.1102873426006796,destabilizing
+RBFOX1,TMTC2,0.15574589778025927,destabilizing
+RBFOX1,KALRN,0.10272107284437161,destabilizing
+RBFOX1,CHD1,0.1100569700705421,destabilizing
+RBFOX1,PPARD,0.0731022682346617,destabilizing
+RBFOX1,BRAF,0.0571477560962154,destabilizing
+RBFOX1,MTMR7,0.1686378419814146,destabilizing
+RBFOX1,EIF4E,0.13082736307564274,destabilizing
+RBFOX1,SOX11,0.07077111273682642,destabilizing
+RBFOX1,EPB41L4B,0.11490625286709232,destabilizing
+RBFOX1,CACNA1B,0.10466011127898188,destabilizing
+RBFOX1,TBC1D5,0.06679861408829742,destabilizing
+RBFOX1,LRRTM4,0.12496932368039942,destabilizing
+RBFOX1,SIRPA,0.14591553332789273,destabilizing
+RBFOX1,PTEN,0.11089400099523844,destabilizing
+RBFOX1,FRY,0.13806454835014279,destabilizing
+RBFOX1,MACROD2,0.15568505617225042,destabilizing
+RBFOX1,FOXN3,0.05928102041761908,destabilizing
+RBFOX1,SHANK2,0.18510388759412272,destabilizing
+RBFOX1,CDK12,0.22597514324421628,destabilizing
+RBFOX1,RFX7,0.14859199257039565,destabilizing
+RBFOX1,UBR5,0.10212311618917133,destabilizing
+RBFOX1,JARID2,0.096561444703039,destabilizing
+RBFOX1,MPHOSPH8,0.11053477666265062,destabilizing
+RBFOX1,DIP2C,0.1140967957446578,destabilizing
+RBFOX1,ZNF423,0.06426372011954547,destabilizing
+RBFOX1,UBR3,0.11623365763222426,destabilizing
+RBFOX1,MGAT5,0.08783325633475889,destabilizing
+RBFOX1,DLG2,0.09174727250252551,destabilizing
+RBFOX1,CHST12,0.26168588576153584,destabilizing
+RBFOX1,EML5,0.1531269721857188,destabilizing
+RBFOX1,CENPP,0.1474570845717382,destabilizing
+RBFOX1,PSME4,0.14359640365786527,destabilizing
+RBFOX1,TMEM106B,0.1820010362784618,destabilizing
+RBFOX1,EPHA5,0.1295214644100829,destabilizing
+RBFOX1,KCNB2,0.1299117434652461,destabilizing
+RBFOX1,ZNF83,0.08981523710219069,destabilizing
+RBFOX1,SOX6,0.07637178842074945,destabilizing
+RBFOX1,ZNF521,0.13104863804851297,destabilizing
+RBFOX1,PLEKHA5,0.07392637621709704,destabilizing
+RBFOX1,DTL,0.11163322041523713,destabilizing
+RBFOX1,NOVA1,0.1686303480861222,destabilizing
+RBFOX1,CCNY,0.143353029332022,destabilizing
+RBFOX1,ARIH1,0.1175637959164402,destabilizing
+RBFOX1,EPB41L5,0.09407144105194354,destabilizing
+RBFOX1,GPR158,0.14630832802762186,destabilizing
+RBFOX1,NCOA2,0.09916867112518622,destabilizing
+RBFOX1,ALK,0.11319849646562999,destabilizing
+RBFOX1,ACACA,0.09931835858706844,destabilizing
+RBFOX1,IFT172,0.1317705414931287,destabilizing
+RBFOX1,CCNT1,0.08443814187984544,destabilizing
+RBFOX1,DTWD2,0.142935605630304,destabilizing
+RBFOX1,SIK3,0.11379753847489857,destabilizing
+RBFOX1,CPEB3,0.15418583788814008,destabilizing
+RBFOX1,CADM2,0.07064355495386278,destabilizing
+RBFOX1,XKR6,0.16244358927021565,destabilizing
+RBFOX1,CADPS,0.07269914579011344,destabilizing
+RBFOX1,FGF13,0.07063905623186609,destabilizing
+RBFOX1,TCF20,0.15156161345878916,destabilizing
+RBFOX1,DGKI,0.11527060835852274,destabilizing
+RBFOX1,EXOC6B,0.17188140600516313,destabilizing
+RBFOX1,MAGI3,0.14675114523455693,destabilizing
+RBFOX1,SBF2,0.08924508314106877,destabilizing
+RBFOX1,INPP4B,0.1486280856230231,destabilizing
+RBFOX1,PTPRS,0.15511218102402644,destabilizing
+RBFOX1,CBFA2T2,0.09186912088693201,destabilizing
+RBFOX1,SPDYE3,0.1264747275342288,destabilizing
+RBFOX1,DMD,0.20907887780120912,destabilizing
+RBFOX1,EIF4G3,0.060667649405749854,destabilizing
+RBFOX1,MCU,0.13400399373145686,destabilizing
+RBFOX1,SSH2,0.10155599577675098,destabilizing
+RBFOX1,DOCK3,0.17003969041473438,destabilizing
+RBFOX1,HS6ST3,0.14935797002056247,destabilizing
+RBFOX1,LPP,0.18875503427035667,destabilizing
+RBFOX1,STAG1,0.12102403337961622,destabilizing
+RBFOX1,CAPZA2,0.11236228958466032,destabilizing
+RBFOX1,ADGRL3,0.062072850765751045,destabilizing
+RBFOX1,UBE2R2,0.15963666220045922,destabilizing
+RBFOX1,GTF2IRD1,0.134958762839068,destabilizing
+RBFOX1,CCBE1,0.08313955276543748,destabilizing
+RBFOX1,SBNO1,0.08746202142209802,destabilizing
+RBFOX1,RIMS2,0.07790483648978246,destabilizing
+RBFOX1,IGF1R,0.054507052870570574,destabilizing
+RBFOX1,TRIO,0.0959202212976212,destabilizing
+RBFOX1,BTBD9,0.1279680300296438,destabilizing
+RBFOX1,CNGB1,0.15926436581759953,destabilizing
+RBFOX1,FMN2,0.0982856073261912,destabilizing
+RBFOX1,ENSG00000228222,0.21558927749457493,destabilizing
+RBFOX1,ATXN1,0.054373639529173345,destabilizing
+RBFOX1,PRKN,0.19190804650608295,destabilizing
+RBFOX1,RASA2,0.12061882773882329,destabilizing
+RBFOX1,PPP1R12B,0.0698527973580052,destabilizing
+RBFOX1,FRMD4A,0.13513001343354158,destabilizing
+RBFOX1,CAMK1D,0.06646511370092519,destabilizing
+RBFOX1,PARD3,0.06491825542795565,destabilizing
+RBFOX1,SEMA6D,0.1201182524529154,destabilizing
+RBFOX1,WIPF2,0.122872520620216,destabilizing
+RBFOX1,DLEU1,0.18482531977447306,destabilizing
+RBFOX1,TSHZ2,0.07487601538931822,destabilizing
+RBFOX1,MED13L,0.09612980640531622,destabilizing
+RBFOX1,KAZN,0.12678117337419656,destabilizing
+RBFOX1,KANSL1,0.06492849074091078,destabilizing
+RBFOX1,FRMD5,0.10870199596272233,destabilizing
+RBFOX1,LINC00174,0.11625773000507862,destabilizing
+RBFOX1,PPM1E,0.14110935750817585,destabilizing
+RBFOX1,ARL3,0.06340394347887422,destabilizing
+RBFOX1,MBD5,0.11636497675108767,destabilizing
+RBFOX1,ELAVL3,0.12229616602518242,destabilizing
+RBFOX1,SLIT2,0.21978817226342257,destabilizing
+RBFOX1,CLASP1,0.10431462361141189,destabilizing
+RBFOX1,DOCK4,0.06400074136983622,destabilizing
+RBFOX1,UNC5C,0.11702001719214945,destabilizing
+RBFOX1,CACNA2D3,-0.08436479423899855,stabilizing
+RBFOX1,RC3H1,0.10408828540271212,destabilizing
+RBFOX1,NEGR1,0.13030906918949928,destabilizing
+RBFOX1,ENOX1,0.18450552391302036,destabilizing
+RBFOX1,SCUBE1,0.08960091192817882,destabilizing
+RBFOX1,GPHN,0.09060330480457707,destabilizing
+RBFOX1,NAV3,0.1877320138922972,destabilizing
+RBFOX1,TOMM22,0.1546985856348792,destabilizing
+RBFOX1,MBNL2,0.06483621826976119,destabilizing
+RBFOX1,MAGI2,0.08393216106621688,destabilizing
+RBFOX1,LSAMP,0.0883137445443174,destabilizing
+RBFOX1,AKAP6,0.11895357181448785,destabilizing
+RBFOX1,TMED2,0.08102742034034897,destabilizing
+RBFOX1,ZBTB20,0.14467944969952962,destabilizing
+RBFOX1,GRIK2,0.12333020052974458,destabilizing
+RBFOX1,LRRC37A3,0.1858264625669543,destabilizing
+RBFOX1,EYS,0.08874183202853854,destabilizing
+RBFOX1,ARID1B,0.0984044841964908,destabilizing
+RBFOX1,PRKCE,0.08139154558796938,destabilizing
+RBFOX1,RBFOX1,-0.43631944765007097,stabilizing
+RBFOX1,SDK1,0.08395368962359363,destabilizing
+RBFOX1,NRG1,0.05214081837700307,destabilizing
+RBFOX1,MLLT3,0.17836792421315528,destabilizing
+RBFOX1,FMN1,0.0625545728116648,destabilizing
+RBFOX1,ADGRB3,0.08762518884831798,destabilizing
+RBFOX1,ROBO1,0.14877378073953718,destabilizing
+RBFOX1,SYPL1,0.08629682685512384,destabilizing
+RBFOX1,PTPRD,0.1298569728812735,destabilizing
+RBFOX1,FAM155A,0.13198160208236454,destabilizing
+RBFOX1,LARP1B,0.1129347535699814,destabilizing
+RBFOX2,TRERF1,0.27777567622123667,destabilizing
+RBFOX2,SORCS1,0.19049617133716062,destabilizing
+RBFOX2,NCOA1,0.10854528379041228,destabilizing
+RBFOX2,COPA,0.09570899595138288,destabilizing
+RBFOX2,FCHSD2,0.14392749007697647,destabilizing
+RBFOX2,PDE3A,0.3400240380645849,destabilizing
+RBFOX2,UNC79,0.2787087990855528,destabilizing
+RBFOX2,DOC2B,0.19043056671449848,destabilizing
+RBFOX2,TMTC2,0.25429604369434017,destabilizing
+RBFOX2,KALRN,0.21268011507585033,destabilizing
+RBFOX2,CHD1,0.16325857315056622,destabilizing
+RBFOX2,PAK3,0.08290036736853552,destabilizing
+RBFOX2,UBE2E2,0.08818723231630975,destabilizing
+RBFOX2,PPARD,0.1302739429453702,destabilizing
+RBFOX2,BRAF,0.09741139772500433,destabilizing
+RBFOX2,RYR2,0.18844145129322615,destabilizing
+RBFOX2,ZNF609,0.0678151207279505,destabilizing
+RBFOX2,MTMR7,0.2737020766040237,destabilizing
+RBFOX2,EIF4E,0.2500294328387943,destabilizing
+RBFOX2,SOX11,0.12170219079060181,destabilizing
+RBFOX2,EPB41L4B,0.20453637147052353,destabilizing
+RBFOX2,CACNA1B,0.1902128537539764,destabilizing
+RBFOX2,TBC1D5,0.12655536919508845,destabilizing
+RBFOX2,LRRTM4,0.2131381951348992,destabilizing
+RBFOX2,SIRPA,0.2377708966156641,destabilizing
+RBFOX2,PTEN,0.169891066252915,destabilizing
+RBFOX2,SPPL3,0.07404752673321997,destabilizing
+RBFOX2,FRY,0.2769635438027201,destabilizing
+RBFOX2,MACROD2,0.2441337503191596,destabilizing
+RBFOX2,FOXN3,0.08730348459271747,destabilizing
+RBFOX2,SHANK2,0.31088669512802986,destabilizing
+RBFOX2,CDK12,0.3512565523899636,destabilizing
+RBFOX2,RFX7,0.24521214586990714,destabilizing
+RBFOX2,UBR5,0.14381701771029917,destabilizing
+RBFOX2,JARID2,0.1364273928802983,destabilizing
+RBFOX2,MPHOSPH8,0.19399039248397262,destabilizing
+RBFOX2,DIP2C,0.21103709234722048,destabilizing
+RBFOX2,ZNF423,0.11026094224784264,destabilizing
+RBFOX2,UBR3,0.1992269454123861,destabilizing
+RBFOX2,MGAT5,0.13562966229498677,destabilizing
+RBFOX2,DLG2,0.17496982712413803,destabilizing
+RBFOX2,CHST12,0.35805603868981273,destabilizing
+RBFOX2,EML5,0.30466553933113005,destabilizing
+RBFOX2,CENPP,0.1640453756248996,destabilizing
+RBFOX2,PSME4,0.257956447460655,destabilizing
+RBFOX2,TMEM106B,0.3152307301997853,destabilizing
+RBFOX2,EPHA5,0.21675589561327954,destabilizing
+RBFOX2,KCNB2,0.23591639804720937,destabilizing
+RBFOX2,ZNF83,0.18265495661113323,destabilizing
+RBFOX2,SOX6,0.13370183619896575,destabilizing
+RBFOX2,ZNF521,0.21695465044098547,destabilizing
+RBFOX2,PLEKHA5,0.18171613225416072,destabilizing
+RBFOX2,DTL,0.20009212809345986,destabilizing
+RBFOX2,NOVA1,0.29628729574730656,destabilizing
+RBFOX2,CCNY,0.2617817145520887,destabilizing
+RBFOX2,ARIH1,0.18708239060532297,destabilizing
+RBFOX2,FAM171B,0.08231347970012501,destabilizing
+RBFOX2,EPB41L5,0.1741739159988619,destabilizing
+RBFOX2,GPR158,0.26710008182354733,destabilizing
+RBFOX2,NCOA2,0.21398489743338,destabilizing
+RBFOX2,PRKCB,0.0702441314810384,destabilizing
+RBFOX2,PUM2,0.05252236656971002,destabilizing
+RBFOX2,MARCKS,0.06968162982340552,destabilizing
+RBFOX2,ALK,0.16270777184729568,destabilizing
+RBFOX2,ACACA,0.1376660012277437,destabilizing
+RBFOX2,ARHGAP26,0.07095057576173532,destabilizing
+RBFOX2,CTNND2,0.12749867412971216,destabilizing
+RBFOX2,IFT172,0.23199898299925947,destabilizing
+RBFOX2,CCNT1,0.14955148651425443,destabilizing
+RBFOX2,ENAH,0.06613703510359992,destabilizing
+RBFOX2,DTWD2,0.2616167605371735,destabilizing
+RBFOX2,SIK3,0.13435712216122078,destabilizing
+RBFOX2,CPEB3,0.25351533604954385,destabilizing
+RBFOX2,CADM2,0.14547695652815817,destabilizing
+RBFOX2,XKR6,0.28398966232715783,destabilizing
+RBFOX2,RMND5A,0.07602544035585729,destabilizing
+RBFOX2,CADPS,0.12315355373703378,destabilizing
+RBFOX2,FGF13,0.08013076338109465,destabilizing
+RBFOX2,TCF20,0.2699902846339232,destabilizing
+RBFOX2,CDKAL1,0.14015091405646818,destabilizing
+RBFOX2,DGKI,0.193921193902489,destabilizing
+RBFOX2,EXOC6B,0.30169190091100023,destabilizing
+RBFOX2,MAGI3,0.22805790894632288,destabilizing
+RBFOX2,SBF2,0.15022163075909056,destabilizing
+RBFOX2,INPP4B,0.24865999905399908,destabilizing
+RBFOX2,ERC1,0.10388486153123307,destabilizing
+RBFOX2,PTPRS,0.3125105973535394,destabilizing
+RBFOX2,CBFA2T2,0.1328876206730821,destabilizing
+RBFOX2,SPDYE3,0.2584913242532052,destabilizing
+RBFOX2,TMEM178B,0.12748284094788814,destabilizing
+RBFOX2,KMT2C,0.0729319018011364,destabilizing
+RBFOX2,CACNA2D1,0.07433798779662418,destabilizing
+RBFOX2,DMD,0.3852467168347535,destabilizing
+RBFOX2,EIF4G3,0.05939978032511579,destabilizing
+RBFOX2,MCU,0.18413611095297946,destabilizing
+RBFOX2,SSH2,0.18914092662572132,destabilizing
+RBFOX2,TCF12,0.06350545969366334,destabilizing
+RBFOX2,DOCK3,0.27688668799737143,destabilizing
+RBFOX2,HS6ST3,0.2859844484529399,destabilizing
+RBFOX2,LPP,0.33562689279821717,destabilizing
+RBFOX2,STAG1,0.20690095560421554,destabilizing
+RBFOX2,CAPZA2,0.22487460822550207,destabilizing
+RBFOX2,ADGRL3,0.1384283061853399,destabilizing
+RBFOX2,PHACTR1,0.07658264579322319,destabilizing
+RBFOX2,UBE2R2,0.27152754855019295,destabilizing
+RBFOX2,GTF2IRD1,0.25025575994734495,destabilizing
+RBFOX2,CCBE1,0.1607440227758107,destabilizing
+RBFOX2,FTX,0.09870641475872133,destabilizing
+RBFOX2,JMJD1C,0.07112274810589721,destabilizing
+RBFOX2,TTC28,0.16201143735920198,destabilizing
+RBFOX2,SBNO1,0.15543656827980065,destabilizing
+RBFOX2,RIMS2,0.1307630693339769,destabilizing
+RBFOX2,IGF1R,0.12097253574372795,destabilizing
+RBFOX2,TRIO,0.15582754123269416,destabilizing
+RBFOX2,KCND2,0.10105963153761952,destabilizing
+RBFOX2,BTBD9,0.262582140100626,destabilizing
+RBFOX2,CNGB1,0.2940785736876868,destabilizing
+RBFOX2,FMN2,0.22410810294006853,destabilizing
+RBFOX2,ENSG00000228222,0.3656719907689072,destabilizing
+RBFOX2,ATXN1,0.08251480236946378,destabilizing
+RBFOX2,PRKN,0.35676398630722383,destabilizing
+RBFOX2,RASA2,0.23338065486914672,destabilizing
+RBFOX2,PPP1R12B,0.14450178574041914,destabilizing
+RBFOX2,FRMD4A,0.20093870777823494,destabilizing
+RBFOX2,CAMK1D,0.10865251982270167,destabilizing
+RBFOX2,PARD3,0.0964065508892039,destabilizing
+RBFOX2,SEMA6D,0.20357587895597762,destabilizing
+RBFOX2,WIPF2,0.2303379571448004,destabilizing
+RBFOX2,DLEU1,0.32092033818532334,destabilizing
+RBFOX2,TSHZ2,0.13437413782286758,destabilizing
+RBFOX2,MED13L,0.154567838724971,destabilizing
+RBFOX2,AFF3,0.09092103488157001,destabilizing
+RBFOX2,KAZN,0.1953701349449864,destabilizing
+RBFOX2,KANSL1,0.13745504738026443,destabilizing
+RBFOX2,FRMD5,0.20209026386305892,destabilizing
+RBFOX2,LINC00174,0.23902349883579974,destabilizing
+RBFOX2,PPM1E,0.2490594432058761,destabilizing
+RBFOX2,ARL3,0.12737850441401552,destabilizing
+RBFOX2,MBD5,0.1996293768924172,destabilizing
+RBFOX2,ELAVL3,0.220933056651702,destabilizing
+RBFOX2,SLIT2,0.337040446655647,destabilizing
+RBFOX2,CLASP1,0.1472149089012007,destabilizing
+RBFOX2,DOCK4,0.0881272224025218,destabilizing
+RBFOX2,UNC5C,0.23244446055348125,destabilizing
+RBFOX2,CACNA2D3,-0.1267874401835708,stabilizing
+RBFOX2,RC3H1,0.1846319437944914,destabilizing
+RBFOX2,NEGR1,0.21099303478290612,destabilizing
+RBFOX2,ENOX1,0.36699168392851506,destabilizing
+RBFOX2,SCUBE1,0.1872651109035167,destabilizing
+RBFOX2,GPHN,0.17750773614133847,destabilizing
+RBFOX2,NAV3,0.296321060360184,destabilizing
+RBFOX2,EBF1,0.09815754372108222,destabilizing
+RBFOX2,TOMM22,0.28564616915109264,destabilizing
+RBFOX2,MBNL2,0.09251193786283088,destabilizing
+RBFOX2,ANKFN1,0.08994565810565122,destabilizing
+RBFOX2,MAGI2,0.13941080101234707,destabilizing
+RBFOX2,LSAMP,0.17927582910699788,destabilizing
+RBFOX2,AKAP6,0.2277651854000528,destabilizing
+RBFOX2,TMED2,0.15413185104576357,destabilizing
+RBFOX2,ZBTB20,0.2037653260058644,destabilizing
+RBFOX2,GRIK2,0.2238178096823621,destabilizing
+RBFOX2,SOX5,0.17636852194946243,destabilizing
+RBFOX2,LRRC37A3,0.3206538421809958,destabilizing
+RBFOX2,TMEM132C,0.09613371681996553,destabilizing
+RBFOX2,EYS,0.16854890510639028,destabilizing
+RBFOX2,ARID1B,0.1674435980567761,destabilizing
+RBFOX2,PRKCE,0.18610916903029412,destabilizing
+RBFOX2,RBFOX1,-0.15934786638162907,stabilizing
+RBFOX2,SDK1,0.11490554194594339,destabilizing
+RBFOX2,NRG1,0.10299027457423439,destabilizing
+RBFOX2,MLLT3,0.30359437746889445,destabilizing
+RBFOX2,AUTS2,0.07244010323289031,destabilizing
+RBFOX2,FMN1,0.12991282115036898,destabilizing
+RBFOX2,ADGRB3,0.1701142224783839,destabilizing
+RBFOX2,ROBO1,0.2529021914199527,destabilizing
+RBFOX2,SYPL1,0.14518944599965034,destabilizing
+RBFOX2,PTPRD,0.19897090651567678,destabilizing
+RBFOX2,FAM155A,0.2669038410120564,destabilizing
+RBFOX2,LARP1B,0.2365101792558233,destabilizing
+RBM3,TRERF1,0.15000927518835802,destabilizing
+RBM3,SORCS1,0.10199820368806956,destabilizing
+RBM3,COPA,0.05788765180103066,destabilizing
+RBM3,PDE3A,0.13341637530309985,destabilizing
+RBM3,UNC79,0.1591227033422507,destabilizing
+RBM3,DOC2B,0.08748730569401139,destabilizing
+RBM3,TMTC2,0.1614854813136012,destabilizing
+RBM3,KALRN,0.08650840764715859,destabilizing
+RBM3,CHD1,0.09746528947684345,destabilizing
+RBM3,PAK3,0.055556777041451,destabilizing
+RBM3,PPARD,0.0904882723025267,destabilizing
+RBM3,RYR2,0.14723729861073706,destabilizing
+RBM3,MTMR7,0.15174733242589178,destabilizing
+RBM3,EIF4E,0.1368199523464089,destabilizing
+RBM3,EPB41L4B,0.08986086792504747,destabilizing
+RBM3,CACNA1B,0.10083569186377028,destabilizing
+RBM3,TBC1D5,0.0627648147461829,destabilizing
+RBM3,LRRTM4,0.12001604013704326,destabilizing
+RBM3,SIRPA,0.13208816427728232,destabilizing
+RBM3,PTEN,0.11404176182424813,destabilizing
+RBM3,FRY,0.16422038914522283,destabilizing
+RBM3,MACROD2,0.12190479992727,destabilizing
+RBM3,FOXN3,0.062492303943586486,destabilizing
+RBM3,SHANK2,0.19871454496491261,destabilizing
+RBM3,CDK12,0.15286904834163093,destabilizing
+RBM3,RFX7,0.1259870130266566,destabilizing
+RBM3,UBR5,0.07172937251866354,destabilizing
+RBM3,JARID2,0.08174372666521605,destabilizing
+RBM3,MPHOSPH8,0.11354924990034727,destabilizing
+RBM3,DIP2C,0.0959496482796831,destabilizing
+RBM3,ZNF423,0.060818359839965294,destabilizing
+RBM3,UBR3,0.13040205185856002,destabilizing
+RBM3,MGAT5,0.06419149358684477,destabilizing
+RBM3,DLG2,0.08128009838612169,destabilizing
+RBM3,CHST12,0.20179731062748263,destabilizing
+RBM3,EML5,0.16836068236527119,destabilizing
+RBM3,PSME4,0.14939676483387843,destabilizing
+RBM3,TMEM106B,0.14853410049237079,destabilizing
+RBM3,EPHA5,0.11429570121567294,destabilizing
+RBM3,KCNB2,0.14544382057702623,destabilizing
+RBM3,ZNF83,0.10359947668080745,destabilizing
+RBM3,SOX6,0.07031427892468464,destabilizing
+RBM3,ZNF521,0.11196337737184463,destabilizing
+RBM3,PLEKHA5,0.10371618569068829,destabilizing
+RBM3,DTL,0.08951684517990811,destabilizing
+RBM3,NOVA1,0.14790644913366605,destabilizing
+RBM3,CCNY,0.12565144714415796,destabilizing
+RBM3,ARIH1,0.11984677882156856,destabilizing
+RBM3,EPB41L5,0.10287211881188982,destabilizing
+RBM3,GPR158,0.1595277850944963,destabilizing
+RBM3,NCOA2,0.10662428369796209,destabilizing
+RBM3,ALK,0.13903851983004362,destabilizing
+RBM3,IFT172,0.13693278937237616,destabilizing
+RBM3,CCNT1,0.08214465842374188,destabilizing
+RBM3,SIK3,0.10870603467632568,destabilizing
+RBM3,CPEB3,0.12663433506601562,destabilizing
+RBM3,CADM2,0.05753236780820878,destabilizing
+RBM3,XKR6,0.14181706898094976,destabilizing
+RBM3,CADPS,0.08494095208769138,destabilizing
+RBM3,TCF20,0.14854145421613252,destabilizing
+RBM3,CDKAL1,0.09459763019901535,destabilizing
+RBM3,DGKI,0.10909270254403595,destabilizing
+RBM3,EXOC6B,0.16403061846035388,destabilizing
+RBM3,MAGI3,0.1271356991326084,destabilizing
+RBM3,SBF2,0.0740932477516465,destabilizing
+RBM3,INPP4B,0.12150737308425405,destabilizing
+RBM3,ERC1,0.06568454860119195,destabilizing
+RBM3,PTPRS,0.1521958656239183,destabilizing
+RBM3,CBFA2T2,0.061925439975523,destabilizing
+RBM3,SPDYE3,0.1050468950356668,destabilizing
+RBM3,TMEM178B,0.06447066735905116,destabilizing
+RBM3,DMD,0.2015784374176003,destabilizing
+RBM3,EIF4G3,0.057103495676059005,destabilizing
+RBM3,MCU,0.13694513955541443,destabilizing
+RBM3,SSH2,0.10867425580528102,destabilizing
+RBM3,DOCK3,0.133349159508234,destabilizing
+RBM3,HS6ST3,0.13933418047702453,destabilizing
+RBM3,LPP,0.12457344125348431,destabilizing
+RBM3,STAG1,0.1079771146892362,destabilizing
+RBM3,CAPZA2,0.10098569433999019,destabilizing
+RBM3,UBE2R2,0.13987488477597954,destabilizing
+RBM3,GTF2IRD1,0.1397076476816284,destabilizing
+RBM3,CCBE1,0.07898186687870602,destabilizing
+RBM3,SBNO1,0.08156117938686552,destabilizing
+RBM3,RIMS2,0.07943971081286388,destabilizing
+RBM3,IGF1R,0.055187029513295106,destabilizing
+RBM3,TRIO,0.0631666227155536,destabilizing
+RBM3,BTBD9,0.12997446707098026,destabilizing
+RBM3,CNGB1,0.15566043629805984,destabilizing
+RBM3,FMN2,0.11639189439067515,destabilizing
+RBM3,ENSG00000228222,0.19052836093570746,destabilizing
+RBM3,ATXN1,0.06219249236796218,destabilizing
+RBM3,PRKN,0.17407929001412936,destabilizing
+RBM3,RASA2,0.09651446521662219,destabilizing
+RBM3,PPP1R12B,0.09152985346864315,destabilizing
+RBM3,FRMD4A,0.10680438481192571,destabilizing
+RBM3,CAMK1D,0.06897221485646308,destabilizing
+RBM3,PARD3,0.055689511472648966,destabilizing
+RBM3,SEMA6D,0.12357619785221585,destabilizing
+RBM3,WIPF2,0.12203329010761567,destabilizing
+RBM3,DLEU1,0.17755897466683462,destabilizing
+RBM3,TSHZ2,0.07937809398748784,destabilizing
+RBM3,MED13L,0.08760550197678604,destabilizing
+RBM3,AFF3,0.055202006060517235,destabilizing
+RBM3,KAZN,0.1193789914157981,destabilizing
+RBM3,FRMD5,0.10683918823504227,destabilizing
+RBM3,LINC00174,0.1127740583407144,destabilizing
+RBM3,PPM1E,0.11878230075254079,destabilizing
+RBM3,ARL3,0.07790506428012538,destabilizing
+RBM3,MBD5,0.11188165920107547,destabilizing
+RBM3,ELAVL3,0.10071612462004591,destabilizing
+RBM3,SLIT2,0.14904518118081123,destabilizing
+RBM3,CLASP1,0.07439468086838098,destabilizing
+RBM3,DOCK4,0.05348601710954862,destabilizing
+RBM3,UNC5C,0.114561526842568,destabilizing
+RBM3,RC3H1,0.09083091346100931,destabilizing
+RBM3,NEGR1,0.13264803054114865,destabilizing
+RBM3,ENOX1,0.20934337571728007,destabilizing
+RBM3,SCUBE1,0.11294584446203063,destabilizing
+RBM3,GPHN,0.11876447164966789,destabilizing
+RBM3,NAV3,0.13788494554185957,destabilizing
+RBM3,EBF1,0.0820456813308908,destabilizing
+RBM3,TOMM22,0.15465409396971436,destabilizing
+RBM3,MBNL2,0.06115315100053345,destabilizing
+RBM3,MAGI2,0.06886039071877369,destabilizing
+RBM3,LSAMP,0.07970586942691461,destabilizing
+RBM3,AKAP6,0.1319469690135359,destabilizing
+RBM3,TMED2,0.09530776062740369,destabilizing
+RBM3,ZBTB20,0.10238881964147312,destabilizing
+RBM3,GRIK2,0.12435039250780029,destabilizing
+RBM3,SOX5,0.09064293759238097,destabilizing
+RBM3,LRRC37A3,0.15117246032275197,destabilizing
+RBM3,EYS,0.06924160688724733,destabilizing
+RBM3,ARID1B,0.07391648908659838,destabilizing
+RBM3,PRKCE,0.08190066476129597,destabilizing
+RBM3,SDK1,0.07779953533604869,destabilizing
+RBM3,MLLT3,0.18304802857018992,destabilizing
+RBM3,AUTS2,0.052826091927951645,destabilizing
+RBM3,FMN1,0.07300788716896953,destabilizing
+RBM3,ADGRB3,0.09398216490141034,destabilizing
+RBM3,ROBO1,0.11280685567452424,destabilizing
+RBM3,SYPL1,0.08604558376891847,destabilizing
+RBM3,PTPRD,0.11598192529949566,destabilizing
+RBM3,FAM155A,0.12791477851316116,destabilizing
+RBM3,LARP1B,0.12175011216076108,destabilizing
+RBM5,TRERF1,0.08254687889383652,destabilizing
+RBM5,PDE3A,0.10527846721656026,destabilizing
+RBM5,UNC79,0.0832380632558118,destabilizing
+RBM5,DOC2B,0.06860421012008448,destabilizing
+RBM5,TMTC2,0.07911492837022537,destabilizing
+RBM5,KALRN,0.07934512916841234,destabilizing
+RBM5,MTMR7,0.09819092331434971,destabilizing
+RBM5,CACNA1B,0.06087940721053755,destabilizing
+RBM5,FRY,0.09948903348495623,destabilizing
+RBM5,MACROD2,0.07043346100430999,destabilizing
+RBM5,CDK12,0.12988628890541498,destabilizing
+RBM5,CHST12,0.14494656053804367,destabilizing
+RBM5,TMEM106B,0.07938786165473141,destabilizing
+RBM5,EPB41L5,0.059760843675173196,destabilizing
+RBM5,NCOA2,0.07803926485313345,destabilizing
+RBM5,ALK,0.10895417775333169,destabilizing
+RBM5,IFT172,0.08197753660487667,destabilizing
+RBM5,XKR6,0.09218338036563314,destabilizing
+RBM5,DGKI,0.067476662529835,destabilizing
+RBM5,MAGI3,0.07904259225603653,destabilizing
+RBM5,DMD,0.1106594818917885,destabilizing
+RBM5,DOCK3,0.07809869232926987,destabilizing
+RBM5,CAPZA2,0.07093845971696479,destabilizing
+RBM5,RASA2,0.07523955747335025,destabilizing
+RBM5,SEMA6D,0.06521658986158807,destabilizing
+RBM5,WIPF2,0.07515494954291285,destabilizing
+RBM5,FRMD5,0.0631154312560575,destabilizing
+RBM5,LINC00174,0.07048112257895121,destabilizing
+RBM5,MBD5,0.05934249051273602,destabilizing
+RBM5,ELAVL3,0.06964495284408054,destabilizing
+RBM5,SLIT2,0.08927243193934342,destabilizing
+RBM5,UNC5C,0.07429611830929489,destabilizing
+RBM5,ENOX1,0.12447141829404518,destabilizing
+RBM5,NAV3,0.08533148120318611,destabilizing
+RBM5,TOMM22,0.08816366990874305,destabilizing
+RBM5,GRIK2,0.06176244227680714,destabilizing
+RBM5,SOX5,0.07361423304534603,destabilizing
+RBM5,LRRC37A3,0.11649182917562326,destabilizing
+RBM5,MLLT3,0.12635071504080486,destabilizing
+RBM5,PTPRD,0.06027235212345913,destabilizing
+RBM10,DOC2B,0.06052084428708951,destabilizing
+RBM10,TMTC2,0.09479117214036606,destabilizing
+RBM10,KALRN,0.07051665230445801,destabilizing
+RBM10,CHD1,0.06299905186860397,destabilizing
+RBM10,MTMR7,0.09091894744154211,destabilizing
+RBM10,EIF4E,0.11576231597040063,destabilizing
+RBM10,FRY,0.09708953951873997,destabilizing
+RBM10,RUNX1T1,0.05726934363636364,destabilizing
+RBM10,MACROD2,0.07646385470506022,destabilizing
+RBM10,MPHOSPH8,0.06990983024728654,destabilizing
+RBM10,EML5,0.10762968976833456,destabilizing
+RBM10,CENPP,0.16516032515129375,destabilizing
+RBM10,TMEM106B,0.08607082032476791,destabilizing
+RBM10,NOVA1,0.10139908255478144,destabilizing
+RBM10,EPB41L5,0.06222353784814414,destabilizing
+RBM10,ALK,0.13787937969827094,destabilizing
+RBM10,IFT172,0.07043597702098697,destabilizing
+RBM10,CCNT1,0.06298733897077902,destabilizing
+RBM10,CADM2,0.05779099393474306,destabilizing
+RBM10,XKR6,0.0850640724631702,destabilizing
+RBM10,MAGI3,0.0733373230574037,destabilizing
+RBM10,DMD,0.07534826000705362,destabilizing
+RBM10,DOCK3,0.09998649753467807,destabilizing
+RBM10,LPP,0.09407448210400633,destabilizing
+RBM10,STAG1,0.06912387054484852,destabilizing
+RBM10,CAPZA2,0.07671045468510275,destabilizing
+RBM10,GTF2IRD1,0.05771141806843754,destabilizing
+RBM10,ENSG00000228222,0.12200969241017173,destabilizing
+RBM10,RASA2,0.07731179188996368,destabilizing
+RBM10,WIPF2,0.08565570825908106,destabilizing
+RBM10,DLEU1,0.11496911790155045,destabilizing
+RBM10,FRMD5,0.06823484504076119,destabilizing
+RBM10,LINC00174,0.08217332843805573,destabilizing
+RBM10,ELAVL3,0.06234354948560465,destabilizing
+RBM10,UNC5C,0.07922307433722688,destabilizing
+RBM10,GRIK2,0.05985019180885013,destabilizing
+RBM10,LRRC37A3,0.10576598904410502,destabilizing
+RBM10,MLLT3,0.10691115761712384,destabilizing
+RBM10,PTPRD,0.07331855174872945,destabilizing
+RBM25,TRERF1,0.1336313572842409,destabilizing
+RBM25,SORCS1,0.09622614655877788,destabilizing
+RBM25,PDE3A,0.11494217669714633,destabilizing
+RBM25,UNC79,0.15504404610097922,destabilizing
+RBM25,DOC2B,0.10879436666391697,destabilizing
+RBM25,TMTC2,0.10881807400221,destabilizing
+RBM25,KALRN,0.0822851246906055,destabilizing
+RBM25,CHD1,0.08261385377784344,destabilizing
+RBM25,PPARD,0.07612909501986947,destabilizing
+RBM25,RYR2,0.10421701636938657,destabilizing
+RBM25,MTMR7,0.1083082064589277,destabilizing
+RBM25,EIF4E,0.10344709894905368,destabilizing
+RBM25,EPB41L4B,0.08511650277215739,destabilizing
+RBM25,CACNA1B,0.08171168133960242,destabilizing
+RBM25,LRRTM4,0.0838833137977742,destabilizing
+RBM25,FRY,0.13431626521933304,destabilizing
+RBM25,MACROD2,0.10147028845033224,destabilizing
+RBM25,SHANK2,0.15336511742461365,destabilizing
+RBM25,CDK12,0.16945281982164412,destabilizing
+RBM25,RFX7,0.11083669917517788,destabilizing
+RBM25,JARID2,0.05880706938413621,destabilizing
+RBM25,MPHOSPH8,0.11003958767000355,destabilizing
+RBM25,DIP2C,0.07086614525302379,destabilizing
+RBM25,UBR3,0.09155612684774683,destabilizing
+RBM25,DLG2,0.0801786360288054,destabilizing
+RBM25,CHST12,0.20143804193936182,destabilizing
+RBM25,EML5,0.12748085549973806,destabilizing
+RBM25,CENPP,0.15732562300610292,destabilizing
+RBM25,PSME4,0.12371337527173269,destabilizing
+RBM25,TMEM106B,0.09860859024135854,destabilizing
+RBM25,EPHA5,0.09038313593701781,destabilizing
+RBM25,KCNB2,0.1498015530434976,destabilizing
+RBM25,ZNF83,0.06700417785080738,destabilizing
+RBM25,SOX6,0.06992995560159485,destabilizing
+RBM25,ZNF521,0.09419306386257405,destabilizing
+RBM25,PLEKHA5,0.059933110041538826,destabilizing
+RBM25,NOVA1,0.12312320128956138,destabilizing
+RBM25,CCNY,0.1473403802497396,destabilizing
+RBM25,ARIH1,0.08186813792370763,destabilizing
+RBM25,EPB41L5,0.07508924277499485,destabilizing
+RBM25,GPR158,0.09417812650010143,destabilizing
+RBM25,NCOA2,0.08057007445847128,destabilizing
+RBM25,ALK,0.14572483623506427,destabilizing
+RBM25,IFT172,0.11560668274318411,destabilizing
+RBM25,CCNT1,0.0748412282053983,destabilizing
+RBM25,DTWD2,0.1655153935795376,destabilizing
+RBM25,SIK3,0.09519891563148984,destabilizing
+RBM25,CPEB3,0.1133383691156439,destabilizing
+RBM25,XKR6,0.13094418650646505,destabilizing
+RBM25,TCF20,0.11478422709392144,destabilizing
+RBM25,DGKI,0.1111641145307555,destabilizing
+RBM25,EXOC6B,0.14671399505809535,destabilizing
+RBM25,MAGI3,0.13355128349018133,destabilizing
+RBM25,SBF2,0.058728821021703834,destabilizing
+RBM25,INPP4B,0.08765514325775275,destabilizing
+RBM25,PTPRS,0.1280751948349715,destabilizing
+RBM25,SPDYE3,0.07175279343788946,destabilizing
+RBM25,DMD,0.1786580436157926,destabilizing
+RBM25,MCU,0.07044875377556507,destabilizing
+RBM25,SSH2,0.08261246368082727,destabilizing
+RBM25,DOCK3,0.13576393610287005,destabilizing
+RBM25,HS6ST3,0.112955091963018,destabilizing
+RBM25,LPP,0.0971860463324057,destabilizing
+RBM25,STAG1,0.08895130199802713,destabilizing
+RBM25,CAPZA2,0.12157090416270383,destabilizing
+RBM25,PHACTR1,0.06387263216006024,destabilizing
+RBM25,UBE2R2,0.11604506951575902,destabilizing
+RBM25,GTF2IRD1,0.0936878050935419,destabilizing
+RBM25,TTC28,0.07894410585558617,destabilizing
+RBM25,SBNO1,0.07610940141078179,destabilizing
+RBM25,BTBD9,0.12031722051541144,destabilizing
+RBM25,CNGB1,0.14376043239056432,destabilizing
+RBM25,ENSG00000228222,0.18177403690749822,destabilizing
+RBM25,PRKN,0.17621448274370266,destabilizing
+RBM25,RASA2,0.10559209120072653,destabilizing
+RBM25,FRMD4A,0.09956967139916187,destabilizing
+RBM25,SEMA6D,0.0717792424057004,destabilizing
+RBM25,WIPF2,0.1166608181366104,destabilizing
+RBM25,DLEU1,0.12722248557602622,destabilizing
+RBM25,TSHZ2,0.08335497041689406,destabilizing
+RBM25,MED13L,0.07959078655695158,destabilizing
+RBM25,KANSL1,0.0763366442338564,destabilizing
+RBM25,FRMD5,0.11858980968917848,destabilizing
+RBM25,LINC00174,0.09866027438190847,destabilizing
+RBM25,PPM1E,0.10055519813366506,destabilizing
+RBM25,ARL3,0.09130273160347903,destabilizing
+RBM25,MBD5,0.07343394605660236,destabilizing
+RBM25,ELAVL3,0.11364503532428846,destabilizing
+RBM25,SLIT2,0.11517574650187173,destabilizing
+RBM25,CLASP1,0.08149987568015499,destabilizing
+RBM25,UNC5C,0.1226779691109479,destabilizing
+RBM25,RC3H1,0.05951805687282728,destabilizing
+RBM25,NEGR1,0.11282242109148034,destabilizing
+RBM25,ENOX1,0.16923532646028538,destabilizing
+RBM25,SCUBE1,0.08486256373337628,destabilizing
+RBM25,GPHN,0.10080367743223193,destabilizing
+RBM25,NAV3,0.12431998732501015,destabilizing
+RBM25,TOMM22,0.1127132729374094,destabilizing
+RBM25,ANKFN1,0.05526241390830434,destabilizing
+RBM25,MAGI2,0.0676220313850716,destabilizing
+RBM25,LSAMP,0.057424957349592486,destabilizing
+RBM25,AKAP6,0.10960094930410784,destabilizing
+RBM25,TMED2,0.0883290081054703,destabilizing
+RBM25,ZBTB20,0.10266433059876172,destabilizing
+RBM25,GRIK2,0.10202658308889438,destabilizing
+RBM25,LRRC37A3,0.16750040525103005,destabilizing
+RBM25,EYS,0.08474375467048062,destabilizing
+RBM25,ARID1B,0.08152902984741336,destabilizing
+RBM25,PRKCE,0.06779182512046032,destabilizing
+RBM25,RBFOX1,-0.07336757998942722,stabilizing
+RBM25,MLLT3,0.1866306070221314,destabilizing
+RBM25,FMN1,0.057447764303954145,destabilizing
+RBM25,ROBO1,0.10104911151718844,destabilizing
+RBM25,PTPRD,0.08447776598715571,destabilizing
+RBM25,FAM155A,0.11686677759901154,destabilizing
+RBM25,LARP1B,0.10601438638344143,destabilizing
+RBM39,TRERF1,0.1964710296689071,destabilizing
+RBM39,SORCS1,0.1461580620682043,destabilizing
+RBM39,FCHSD2,0.10590138256820496,destabilizing
+RBM39,PDE3A,0.23730541361232793,destabilizing
+RBM39,UNC79,0.23125508650417542,destabilizing
+RBM39,DOC2B,0.14115852849834687,destabilizing
+RBM39,TMTC2,0.2059483764151876,destabilizing
+RBM39,KALRN,0.13116727335524622,destabilizing
+RBM39,CHD1,0.09633538898125758,destabilizing
+RBM39,PAK3,0.061428748361574,destabilizing
+RBM39,UBE2E2,0.10992240172095515,destabilizing
+RBM39,PPARD,0.14137135150825544,destabilizing
+RBM39,TOX,0.08468540427966598,destabilizing
+RBM39,RYR2,0.19503361655743778,destabilizing
+RBM39,MTMR7,0.19437928329786,destabilizing
+RBM39,EIF4E,0.2133704682755893,destabilizing
+RBM39,SOX11,0.09084991625405281,destabilizing
+RBM39,EPB41L4B,0.13056772012432658,destabilizing
+RBM39,CACNA1B,0.1398427397368596,destabilizing
+RBM39,TBC1D5,0.08901660651727578,destabilizing
+RBM39,LRRTM4,0.15450310152818947,destabilizing
+RBM39,SIRPA,0.1897774239340587,destabilizing
+RBM39,PTEN,0.1466626547945346,destabilizing
+RBM39,FRY,0.2018644991647858,destabilizing
+RBM39,MACROD2,0.17852478367344168,destabilizing
+RBM39,FOXN3,0.059692381571208646,destabilizing
+RBM39,SHANK2,0.2554159025530829,destabilizing
+RBM39,CDK12,0.2720647102731622,destabilizing
+RBM39,RFX7,0.20208495582893607,destabilizing
+RBM39,UBR5,0.09621171101068662,destabilizing
+RBM39,JARID2,0.08888993287302828,destabilizing
+RBM39,MPHOSPH8,0.15208107680645983,destabilizing
+RBM39,DIP2C,0.128579249236514,destabilizing
+RBM39,ZNF423,0.07852296646963453,destabilizing
+RBM39,UBR3,0.12430275552155058,destabilizing
+RBM39,MGAT5,0.08592322602525235,destabilizing
+RBM39,DLG2,0.13625113348255596,destabilizing
+RBM39,CHST12,0.2896038372874915,destabilizing
+RBM39,EML5,0.19194615268350249,destabilizing
+RBM39,CENPP,0.22583387274811004,destabilizing
+RBM39,PSME4,0.22052149010720645,destabilizing
+RBM39,TMEM106B,0.23056519104188308,destabilizing
+RBM39,EPHA5,0.1658649812338,destabilizing
+RBM39,KCNB2,0.20667065954526742,destabilizing
+RBM39,ZNF83,0.14782345897999652,destabilizing
+RBM39,SOX6,0.11137443777285666,destabilizing
+RBM39,ZNF521,0.17506259733326254,destabilizing
+RBM39,PLEKHA5,0.10341210615518343,destabilizing
+RBM39,NOVA1,0.22839389445874536,destabilizing
+RBM39,CCNY,0.19220926307199515,destabilizing
+RBM39,ARIH1,0.14385818278960394,destabilizing
+RBM39,EPB41L5,0.1244053973987491,destabilizing
+RBM39,GPR158,0.19323107192580372,destabilizing
+RBM39,NCOA2,0.15272786971031221,destabilizing
+RBM39,ALK,0.1784603724242128,destabilizing
+RBM39,ACACA,0.08871894605468143,destabilizing
+RBM39,CTNND2,0.059700022617935763,destabilizing
+RBM39,IFT172,0.17749456087336588,destabilizing
+RBM39,CCNT1,0.111724156387822,destabilizing
+RBM39,DTWD2,0.22470555534998055,destabilizing
+RBM39,SIK3,0.1660485352974539,destabilizing
+RBM39,CPEB3,0.21472996656079066,destabilizing
+RBM39,CADM2,0.07084229555207769,destabilizing
+RBM39,XKR6,0.2206811145380342,destabilizing
+RBM39,RMND5A,0.06407760158308617,destabilizing
+RBM39,CADPS,0.0960712115203777,destabilizing
+RBM39,TCF20,0.2010377533774998,destabilizing
+RBM39,CDKAL1,0.09037429410011294,destabilizing
+RBM39,DGKI,0.13774353604950848,destabilizing
+RBM39,EXOC6B,0.24678271006754454,destabilizing
+RBM39,MAGI3,0.2120760776390036,destabilizing
+RBM39,SBF2,0.10276523082312156,destabilizing
+RBM39,INPP4B,0.17068740737144183,destabilizing
+RBM39,ERC1,0.057830904552546636,destabilizing
+RBM39,PTPRS,0.21826730149713583,destabilizing
+RBM39,CBFA2T2,0.09201001800186985,destabilizing
+RBM39,SPDYE3,0.1821830577056871,destabilizing
+RBM39,TMEM178B,0.06540414499013082,destabilizing
+RBM39,DMD,0.23051999653202085,destabilizing
+RBM39,MCU,0.16244872940240956,destabilizing
+RBM39,SSH2,0.15665086424191008,destabilizing
+RBM39,DOCK3,0.23021780179922127,destabilizing
+RBM39,HS6ST3,0.1855297381655085,destabilizing
+RBM39,LPP,0.23647570936576864,destabilizing
+RBM39,STAG1,0.13353527395881046,destabilizing
+RBM39,CAPZA2,0.162161997293412,destabilizing
+RBM39,ADGRL3,0.09920779345128822,destabilizing
+RBM39,UBE2R2,0.19119001155200854,destabilizing
+RBM39,GTF2IRD1,0.17453757784365995,destabilizing
+RBM39,CCBE1,0.06936252068492486,destabilizing
+RBM39,TTC28,0.10592539017709407,destabilizing
+RBM39,SBNO1,0.09583193058251366,destabilizing
+RBM39,RIMS2,0.11356932931786072,destabilizing
+RBM39,IGF1R,0.0821221715329162,destabilizing
+RBM39,TRIO,0.07912161245191415,destabilizing
+RBM39,KCND2,0.05775687292474811,destabilizing
+RBM39,BTBD9,0.1971750826623132,destabilizing
+RBM39,CNGB1,0.2021091494504592,destabilizing
+RBM39,FMN2,0.14896489926610723,destabilizing
+RBM39,ENSG00000228222,0.2991543215811933,destabilizing
+RBM39,PRKN,0.2240372772106173,destabilizing
+RBM39,RASA2,0.2034685651818528,destabilizing
+RBM39,PPP1R12B,0.09951350106434038,destabilizing
+RBM39,FRMD4A,0.1296467056980899,destabilizing
+RBM39,CAMK1D,0.06475324250071286,destabilizing
+RBM39,SEMA6D,0.1516246851752296,destabilizing
+RBM39,WIPF2,0.18155921449529552,destabilizing
+RBM39,DLEU1,0.22315795971056923,destabilizing
+RBM39,TSHZ2,0.08690964592025263,destabilizing
+RBM39,MED13L,0.08786043550925128,destabilizing
+RBM39,KAZN,0.14349363581070704,destabilizing
+RBM39,KANSL1,0.09211980163156847,destabilizing
+RBM39,FRMD5,0.15734823622071423,destabilizing
+RBM39,LINC00174,0.17746687920317014,destabilizing
+RBM39,PPM1E,0.14751338583013437,destabilizing
+RBM39,ARL3,0.09815561185875818,destabilizing
+RBM39,MBD5,0.13940359690683046,destabilizing
+RBM39,ELAVL3,0.1701393493400984,destabilizing
+RBM39,SLIT2,0.23235413384534412,destabilizing
+RBM39,CLASP1,0.11387821641080743,destabilizing
+RBM39,UNC5C,0.16583852301173702,destabilizing
+RBM39,CACNA2D3,-0.0838903986864323,stabilizing
+RBM39,RC3H1,0.1268404878228857,destabilizing
+RBM39,NEGR1,0.17080773415225065,destabilizing
+RBM39,ENOX1,0.2667905102086035,destabilizing
+RBM39,SCUBE1,0.10719646675017233,destabilizing
+RBM39,GPHN,0.13931827691883547,destabilizing
+RBM39,NAV3,0.20188775739081893,destabilizing
+RBM39,TOMM22,0.19394351853506964,destabilizing
+RBM39,MAGI2,0.06872321012033666,destabilizing
+RBM39,LSAMP,0.10801041991655495,destabilizing
+RBM39,AKAP6,0.18684488707734836,destabilizing
+RBM39,TMED2,0.1202082472969939,destabilizing
+RBM39,ZBTB20,0.16321835170928606,destabilizing
+RBM39,GRIK2,0.1422030021812233,destabilizing
+RBM39,SOX5,0.12537517088541955,destabilizing
+RBM39,LRRC37A3,0.25378198742983904,destabilizing
+RBM39,TMEM132C,0.055566236685437545,destabilizing
+RBM39,EYS,0.11286917484688008,destabilizing
+RBM39,ARID1B,0.10841063538956294,destabilizing
+RBM39,PRKCE,0.11511614485546053,destabilizing
+RBM39,RBFOX1,-0.11513921964722708,stabilizing
+RBM39,SDK1,0.08369980948709597,destabilizing
+RBM39,NRG1,0.05531718219927604,destabilizing
+RBM39,MLLT3,0.261933381341859,destabilizing
+RBM39,FMN1,0.08684383639861819,destabilizing
+RBM39,ADGRB3,0.09597553646503014,destabilizing
+RBM39,ROBO1,0.1530085599585113,destabilizing
+RBM39,SYPL1,0.08376260615870071,destabilizing
+RBM39,PTPRD,0.13846086534273286,destabilizing
+RBM39,FAM155A,0.14802282811417003,destabilizing
+RBM39,LARP1B,0.16552354494936966,destabilizing
+SRSF3,TRERF1,0.2221988253478126,destabilizing
+SRSF3,SORCS1,0.1357403555389706,destabilizing
+SRSF3,NCOA1,0.07380031686655292,destabilizing
+SRSF3,COPA,0.08205304049499397,destabilizing
+SRSF3,FCHSD2,0.08780587092529943,destabilizing
+SRSF3,PDE3A,0.1919685260253324,destabilizing
+SRSF3,UNC79,0.207586480601078,destabilizing
+SRSF3,DOC2B,0.148131517568564,destabilizing
+SRSF3,TMTC2,0.23508849869183773,destabilizing
+SRSF3,KALRN,0.12805182531767256,destabilizing
+SRSF3,CHD1,0.0948281106538144,destabilizing
+SRSF3,UBE2E2,0.09779523749118467,destabilizing
+SRSF3,PPARD,0.10860181271599907,destabilizing
+SRSF3,TOX,0.10652923508169702,destabilizing
+SRSF3,BRAF,0.10285078990950114,destabilizing
+SRSF3,RYR2,0.20934889902617987,destabilizing
+SRSF3,MTMR7,0.20646043603361933,destabilizing
+SRSF3,EIF4E,0.23391893881460707,destabilizing
+SRSF3,SOX11,0.08732905248434833,destabilizing
+SRSF3,EPB41L4B,0.08908295844086198,destabilizing
+SRSF3,CACNA1B,0.12119731386791077,destabilizing
+SRSF3,TBC1D5,0.0624382971978803,destabilizing
+SRSF3,WSB1,0.05498702919418591,destabilizing
+SRSF3,LRRTM4,0.12214293002638651,destabilizing
+SRSF3,SIRPA,0.15226220809294616,destabilizing
+SRSF3,PTEN,0.1258354629362296,destabilizing
+SRSF3,FRY,0.26505189118346484,destabilizing
+SRSF3,RUNX1T1,0.0889619848920359,destabilizing
+SRSF3,MACROD2,0.1970236149562263,destabilizing
+SRSF3,SHANK2,0.277591290707965,destabilizing
+SRSF3,CDK12,0.2755086143233137,destabilizing
+SRSF3,RFX7,0.19910829979717748,destabilizing
+SRSF3,UBR5,0.0714567356102544,destabilizing
+SRSF3,JARID2,0.1088529082550248,destabilizing
+SRSF3,MPHOSPH8,0.19299042433975971,destabilizing
+SRSF3,DIP2C,0.13138364138718267,destabilizing
+SRSF3,UBR3,0.11025736803996396,destabilizing
+SRSF3,DLG2,0.1307620711797404,destabilizing
+SRSF3,CHST12,0.3020580875494834,destabilizing
+SRSF3,EML5,0.2201481439864582,destabilizing
+SRSF3,CENPP,0.4092786805286205,destabilizing
+SRSF3,PSME4,0.1869293086023095,destabilizing
+SRSF3,TMEM106B,0.1896863638322485,destabilizing
+SRSF3,RABGAP1L,0.06314256574812244,destabilizing
+SRSF3,EPHA5,0.14473927328331837,destabilizing
+SRSF3,KCNB2,0.2801458039605575,destabilizing
+SRSF3,ZNF83,0.14377907981465032,destabilizing
+SRSF3,SOX6,0.1439173681244193,destabilizing
+SRSF3,ZNF521,0.18672429825607026,destabilizing
+SRSF3,PLEKHA5,0.11672487349922306,destabilizing
+SRSF3,NOVA1,0.25526276872673204,destabilizing
+SRSF3,CCNY,0.20847174423361545,destabilizing
+SRSF3,ARIH1,0.14987798165966965,destabilizing
+SRSF3,EPB41L5,0.12026535828875436,destabilizing
+SRSF3,GPR158,0.18789169247439033,destabilizing
+SRSF3,NCOA2,0.10562739227788742,destabilizing
+SRSF3,ALK,0.3173823183783115,destabilizing
+SRSF3,ARHGAP26,0.08032771401478019,destabilizing
+SRSF3,CTNND2,0.07428591042643581,destabilizing
+SRSF3,IFT172,0.183566521317812,destabilizing
+SRSF3,CCNT1,0.11469190784954938,destabilizing
+SRSF3,DTWD2,0.33396413549697024,destabilizing
+SRSF3,SIK3,0.19198174603098575,destabilizing
+SRSF3,CPEB3,0.22066340495373624,destabilizing
+SRSF3,CADM2,0.10363606526785141,destabilizing
+SRSF3,XKR6,0.20202991960064032,destabilizing
+SRSF3,RMND5A,0.06669555766750342,destabilizing
+SRSF3,CADPS,0.10397749220202868,destabilizing
+SRSF3,FGF13,0.09478237609792228,destabilizing
+SRSF3,TCF20,0.17999164321782996,destabilizing
+SRSF3,CDKAL1,0.12235821761784015,destabilizing
+SRSF3,DGKI,0.1781147753888703,destabilizing
+SRSF3,EXOC6B,0.26677731652025716,destabilizing
+SRSF3,MAGI3,0.1868391536334345,destabilizing
+SRSF3,SBF2,0.09853997768123166,destabilizing
+SRSF3,INPP4B,0.13866109713325395,destabilizing
+SRSF3,PTPRS,0.19666578338570598,destabilizing
+SRSF3,CBFA2T2,0.07848713639044298,destabilizing
+SRSF3,SPDYE3,0.1282664945999353,destabilizing
+SRSF3,TMEM178B,0.09282398674054658,destabilizing
+SRSF3,DMD,0.26893531921074093,destabilizing
+SRSF3,EIF4G3,0.07756751210583533,destabilizing
+SRSF3,MCU,0.18425171277570276,destabilizing
+SRSF3,SSH2,0.15200399980382087,destabilizing
+SRSF3,DOCK3,0.2287853169071147,destabilizing
+SRSF3,HS6ST3,0.14172836871983868,destabilizing
+SRSF3,LPP,0.1550928195288778,destabilizing
+SRSF3,STAG1,0.12877721639867232,destabilizing
+SRSF3,CAPZA2,0.1654306917231939,destabilizing
+SRSF3,ADGRL3,0.08717962978384626,destabilizing
+SRSF3,PHACTR1,0.12949971934450305,destabilizing
+SRSF3,UBE2R2,0.17048273876013628,destabilizing
+SRSF3,GTF2IRD1,0.12354005102269053,destabilizing
+SRSF3,CCBE1,0.06296906992371776,destabilizing
+SRSF3,FTX,0.06783523998662361,destabilizing
+SRSF3,JMJD1C,0.07622257808637778,destabilizing
+SRSF3,TTC28,0.1452415394443281,destabilizing
+SRSF3,SBNO1,0.07528481652142995,destabilizing
+SRSF3,RIMS2,0.11966358006010946,destabilizing
+SRSF3,IGF1R,0.06064501487435406,destabilizing
+SRSF3,BTBD9,0.1618401207673114,destabilizing
+SRSF3,CNGB1,0.18223741350378772,destabilizing
+SRSF3,FMN2,0.15339054974496316,destabilizing
+SRSF3,ENSG00000228222,0.29588368023180034,destabilizing
+SRSF3,ATXN1,0.07232640898272312,destabilizing
+SRSF3,SYN3,0.09700830292351578,destabilizing
+SRSF3,PRKN,0.1877066156358321,destabilizing
+SRSF3,RASA2,0.19459633510947094,destabilizing
+SRSF3,PPP1R12B,0.12340516808085923,destabilizing
+SRSF3,FRMD4A,0.12159516576903069,destabilizing
+SRSF3,CAMK1D,0.07261281906053889,destabilizing
+SRSF3,SEMA6D,0.1806614674415487,destabilizing
+SRSF3,WIPF2,0.18978683385212564,destabilizing
+SRSF3,DLEU1,0.2376595818468475,destabilizing
+SRSF3,TSHZ2,0.1217928176270903,destabilizing
+SRSF3,MED13L,0.11310066057252943,destabilizing
+SRSF3,KAZN,0.15664240116892234,destabilizing
+SRSF3,KANSL1,0.11276609649601692,destabilizing
+SRSF3,FRMD5,0.16793093318275473,destabilizing
+SRSF3,LINC00174,0.17160478784195354,destabilizing
+SRSF3,PPM1E,0.13642426834889326,destabilizing
+SRSF3,ARL3,0.1449991453078381,destabilizing
+SRSF3,MBD5,0.15420317895415683,destabilizing
+SRSF3,ELAVL3,0.15844505850120758,destabilizing
+SRSF3,SLIT2,0.1981251211353916,destabilizing
+SRSF3,CLASP1,0.14313969788551564,destabilizing
+SRSF3,UNC5C,0.1813192011179073,destabilizing
+SRSF3,CACNA2D3,-0.0709320398379863,stabilizing
+SRSF3,RC3H1,0.1085936109549655,destabilizing
+SRSF3,NEGR1,0.22544993362700816,destabilizing
+SRSF3,ENOX1,0.25087093295838403,destabilizing
+SRSF3,SCUBE1,0.07879819805797722,destabilizing
+SRSF3,GPHN,0.1347719902277359,destabilizing
+SRSF3,NAV3,0.1932974951439807,destabilizing
+SRSF3,EBF1,0.06935151280169974,destabilizing
+SRSF3,TOMM22,0.22921495073410564,destabilizing
+SRSF3,MBNL2,0.08388713416878031,destabilizing
+SRSF3,ANKFN1,0.08819536986742477,destabilizing
+SRSF3,MAGI2,0.06743025436135738,destabilizing
+SRSF3,LSAMP,0.11322726525525881,destabilizing
+SRSF3,AKAP6,0.18262499296959817,destabilizing
+SRSF3,TMED2,0.13015023375328122,destabilizing
+SRSF3,ZBTB20,0.17330473385614,destabilizing
+SRSF3,GRIK2,0.1500370998706149,destabilizing
+SRSF3,SOX5,0.11292481022326403,destabilizing
+SRSF3,LRRC37A3,0.22750110682114713,destabilizing
+SRSF3,TMEM132C,0.07887623550269686,destabilizing
+SRSF3,EYS,0.13857445962599957,destabilizing
+SRSF3,ARID1B,0.10862864566970742,destabilizing
+SRSF3,PRKCE,0.10233053969250736,destabilizing
+SRSF3,RBFOX1,-0.08618547979978751,stabilizing
+SRSF3,SDK1,0.08600784938092662,destabilizing
+SRSF3,NRG1,0.07930168571796599,destabilizing
+SRSF3,RORA,0.06598475475183048,destabilizing
+SRSF3,MLLT3,0.29111353240585336,destabilizing
+SRSF3,FMN1,0.091824438870805,destabilizing
+SRSF3,ADGRB3,0.08240244807912557,destabilizing
+SRSF3,ROBO1,0.12745785224958633,destabilizing
+SRSF3,SYPL1,0.12942069355423852,destabilizing
+SRSF3,PTPRD,0.15332053624443462,destabilizing
+SRSF3,FAM155A,0.19525881582871793,destabilizing
+SRSF3,LARP1B,0.147695660963295,destabilizing
+SRSF4,TRERF1,0.10132192711595314,destabilizing
+SRSF4,SORCS1,0.06426108520490235,destabilizing
+SRSF4,UNC79,0.12750275718454812,destabilizing
+SRSF4,DOC2B,0.06324218322959682,destabilizing
+SRSF4,TMTC2,0.11797403179501634,destabilizing
+SRSF4,KALRN,0.07474163181611126,destabilizing
+SRSF4,PPARD,0.07095122400146975,destabilizing
+SRSF4,RYR2,0.118515895859407,destabilizing
+SRSF4,MTMR7,0.1263135648094664,destabilizing
+SRSF4,EIF4E,0.1366388422699583,destabilizing
+SRSF4,CACNA1B,0.09929447580841463,destabilizing
+SRSF4,LRRTM4,0.0681995313818645,destabilizing
+SRSF4,SIRPA,0.1034804296013183,destabilizing
+SRSF4,FRY,0.15550188329481712,destabilizing
+SRSF4,MACROD2,0.11747561931537176,destabilizing
+SRSF4,SHANK2,0.16706320863625604,destabilizing
+SRSF4,CDK12,0.18186559295825855,destabilizing
+SRSF4,RFX7,0.10903113671681441,destabilizing
+SRSF4,MPHOSPH8,0.1183576832325959,destabilizing
+SRSF4,DIP2C,0.06719395249971762,destabilizing
+SRSF4,DLG2,0.08120485084857118,destabilizing
+SRSF4,CHST12,0.21969249141575148,destabilizing
+SRSF4,EML5,0.09693092590900494,destabilizing
+SRSF4,CENPP,0.17236897389571507,destabilizing
+SRSF4,PSME4,0.07304880259214358,destabilizing
+SRSF4,TMEM106B,0.11379620554896683,destabilizing
+SRSF4,EPHA5,0.09147584109991738,destabilizing
+SRSF4,KCNB2,0.1664977413914098,destabilizing
+SRSF4,ZNF83,0.10403731989375542,destabilizing
+SRSF4,SOX6,0.08937662566770602,destabilizing
+SRSF4,ZNF521,0.11574817661747876,destabilizing
+SRSF4,NOVA1,0.12230980464591948,destabilizing
+SRSF4,CCNY,0.10402696725836225,destabilizing
+SRSF4,ARIH1,0.08751469594814291,destabilizing
+SRSF4,EPB41L5,0.07918581493599285,destabilizing
+SRSF4,GPR158,0.08845430623660332,destabilizing
+SRSF4,ALK,0.1537676440454039,destabilizing
+SRSF4,IFT172,0.10464345925375661,destabilizing
+SRSF4,CCNT1,0.06587420882862728,destabilizing
+SRSF4,DTWD2,0.1677129634878861,destabilizing
+SRSF4,SIK3,0.07924357717426865,destabilizing
+SRSF4,CPEB3,0.11484775781286202,destabilizing
+SRSF4,XKR6,0.11534889334056936,destabilizing
+SRSF4,CADPS,0.06348118029617514,destabilizing
+SRSF4,FGF13,0.060671614810181164,destabilizing
+SRSF4,TCF20,0.08758876527195897,destabilizing
+SRSF4,CDKAL1,0.0767395424775092,destabilizing
+SRSF4,DGKI,0.09554616373193975,destabilizing
+SRSF4,EXOC6B,0.15514989893641928,destabilizing
+SRSF4,MAGI3,0.11586755570620437,destabilizing
+SRSF4,SBF2,0.06803672071187108,destabilizing
+SRSF4,INPP4B,0.08860233833400669,destabilizing
+SRSF4,PTPRS,0.14712297987718967,destabilizing
+SRSF4,DMD,0.13283793738182265,destabilizing
+SRSF4,MCU,0.09098481843585264,destabilizing
+SRSF4,DOCK3,0.12831071732500596,destabilizing
+SRSF4,HS6ST3,0.09628599561636528,destabilizing
+SRSF4,STAG1,0.07832545982143276,destabilizing
+SRSF4,CAPZA2,0.12417079968399727,destabilizing
+SRSF4,UBE2R2,0.09582739675093335,destabilizing
+SRSF4,GTF2IRD1,0.06611877019958347,destabilizing
+SRSF4,RIMS2,0.060448782021897796,destabilizing
+SRSF4,CNGB1,0.11250010130215281,destabilizing
+SRSF4,FMN2,0.06473125852607049,destabilizing
+SRSF4,ENSG00000228222,0.18427833767245136,destabilizing
+SRSF4,PRKN,0.11781383713252215,destabilizing
+SRSF4,RASA2,0.13075766886846404,destabilizing
+SRSF4,FRMD4A,0.06749961440977843,destabilizing
+SRSF4,SEMA6D,0.07776561402132089,destabilizing
+SRSF4,WIPF2,0.10586184806513912,destabilizing
+SRSF4,DLEU1,0.10910055721896625,destabilizing
+SRSF4,TSHZ2,0.0655491289031031,destabilizing
+SRSF4,KAZN,0.07845601895363524,destabilizing
+SRSF4,FRMD5,0.09266082020532637,destabilizing
+SRSF4,LINC00174,0.10014005074678461,destabilizing
+SRSF4,ARL3,0.07588000119844919,destabilizing
+SRSF4,MBD5,0.0600270279318112,destabilizing
+SRSF4,ELAVL3,0.1139275354708102,destabilizing
+SRSF4,SLIT2,0.11882665000890458,destabilizing
+SRSF4,CLASP1,0.08165527294304503,destabilizing
+SRSF4,UNC5C,0.10623493304396826,destabilizing
+SRSF4,NEGR1,0.10217226643582579,destabilizing
+SRSF4,ENOX1,0.13116027161860394,destabilizing
+SRSF4,GPHN,0.07248334195422564,destabilizing
+SRSF4,NAV3,0.0906797834570871,destabilizing
+SRSF4,TOMM22,0.11890762179861993,destabilizing
+SRSF4,LSAMP,0.06101077057212273,destabilizing
+SRSF4,AKAP6,0.10567253947563056,destabilizing
+SRSF4,TMED2,0.08066512665125945,destabilizing
+SRSF4,ZBTB20,0.07591438347353031,destabilizing
+SRSF4,GRIK2,0.07482250631465305,destabilizing
+SRSF4,LRRC37A3,0.12907040288482763,destabilizing
+SRSF4,EYS,0.08851342903195174,destabilizing
+SRSF4,ARID1B,0.07529455273929496,destabilizing
+SRSF4,PRKCE,0.08137543787942762,destabilizing
+SRSF4,RBFOX1,-0.060056884061394075,stabilizing
+SRSF4,MLLT3,0.17807994218554346,destabilizing
+SRSF4,ROBO1,0.0837675537123918,destabilizing
+SRSF4,SYPL1,0.07216243036622692,destabilizing
+SRSF4,PTPRD,0.0668874722639655,destabilizing
+SRSF4,FAM155A,0.11930562740934841,destabilizing
+SRSF4,LARP1B,0.0800756063522092,destabilizing
+SRSF5,TRERF1,0.13834734779333313,destabilizing
+SRSF5,SORCS1,0.1017481827779521,destabilizing
+SRSF5,FCHSD2,0.08707809335390408,destabilizing
+SRSF5,PDE3A,0.16162976601762422,destabilizing
+SRSF5,UNC79,0.1741795912480174,destabilizing
+SRSF5,DOC2B,0.11077518447347331,destabilizing
+SRSF5,TMTC2,0.14743256324568785,destabilizing
+SRSF5,KALRN,0.1110509367235366,destabilizing
+SRSF5,CHD1,0.0951011795218285,destabilizing
+SRSF5,UBE2E2,0.06640246214826619,destabilizing
+SRSF5,PPARD,0.07229206916184062,destabilizing
+SRSF5,RYR2,0.12590029596974517,destabilizing
+SRSF5,MTMR7,0.16078889919067282,destabilizing
+SRSF5,EIF4E,0.17566935248802137,destabilizing
+SRSF5,EPB41L4B,0.10357606133960265,destabilizing
+SRSF5,CACNA1B,0.10874613099958216,destabilizing
+SRSF5,LRRTM4,0.12850128927216467,destabilizing
+SRSF5,SIRPA,0.14367694495616123,destabilizing
+SRSF5,PTEN,0.10745929392621557,destabilizing
+SRSF5,FRY,0.17203678722860258,destabilizing
+SRSF5,MACROD2,0.15110000874846635,destabilizing
+SRSF5,SHANK2,0.21545538592916574,destabilizing
+SRSF5,CDK12,0.2252770688569138,destabilizing
+SRSF5,RFX7,0.17057330222568484,destabilizing
+SRSF5,UBR5,0.06569001235699717,destabilizing
+SRSF5,JARID2,0.06911727022387194,destabilizing
+SRSF5,MPHOSPH8,0.12560428865291945,destabilizing
+SRSF5,DIP2C,0.117457525716209,destabilizing
+SRSF5,ZNF423,0.05584918345743737,destabilizing
+SRSF5,UBR3,0.10385984322929556,destabilizing
+SRSF5,MGAT5,0.05009669614085667,destabilizing
+SRSF5,DLG2,0.11757424782687796,destabilizing
+SRSF5,CHST12,0.2279204936821902,destabilizing
+SRSF5,EML5,0.14428722424789772,destabilizing
+SRSF5,CENPP,0.1396492613378111,destabilizing
+SRSF5,PSME4,0.15350369722182483,destabilizing
+SRSF5,TMEM106B,0.16465233990544884,destabilizing
+SRSF5,EPHA5,0.11461094700906792,destabilizing
+SRSF5,KCNB2,0.15723600766853912,destabilizing
+SRSF5,ZNF83,0.1068462813016775,destabilizing
+SRSF5,SOX6,0.07998132329970835,destabilizing
+SRSF5,ZNF521,0.12071176386008234,destabilizing
+SRSF5,PLEKHA5,0.10462183743362893,destabilizing
+SRSF5,NOVA1,0.18824321223269105,destabilizing
+SRSF5,CCNY,0.14086118448234417,destabilizing
+SRSF5,ARIH1,0.09103134571899286,destabilizing
+SRSF5,EPB41L5,0.11322875969291596,destabilizing
+SRSF5,GPR158,0.162430545192072,destabilizing
+SRSF5,NCOA2,0.12468819084168101,destabilizing
+SRSF5,MARCKS,0.05935950845456454,destabilizing
+SRSF5,ALK,0.12725507096190913,destabilizing
+SRSF5,ACACA,0.0721655741064546,destabilizing
+SRSF5,ARHGAP26,0.05752329599425094,destabilizing
+SRSF5,CTNND2,0.058514602493669625,destabilizing
+SRSF5,IFT172,0.14763863368219762,destabilizing
+SRSF5,CCNT1,0.08239565043689674,destabilizing
+SRSF5,DTWD2,0.17705408092604885,destabilizing
+SRSF5,SIK3,0.10267999126396979,destabilizing
+SRSF5,CPEB3,0.18320344675985298,destabilizing
+SRSF5,CADM2,0.09431235673951117,destabilizing
+SRSF5,XKR6,0.16577567142473987,destabilizing
+SRSF5,CADPS,0.07116546387320413,destabilizing
+SRSF5,TCF20,0.1429435393999108,destabilizing
+SRSF5,CDKAL1,0.07595660548459866,destabilizing
+SRSF5,DGKI,0.10765793881329007,destabilizing
+SRSF5,EXOC6B,0.17452221729803022,destabilizing
+SRSF5,MAGI3,0.14108250226578228,destabilizing
+SRSF5,SBF2,0.08234756869357594,destabilizing
+SRSF5,INPP4B,0.12580080515390493,destabilizing
+SRSF5,ERC1,0.05502117708750193,destabilizing
+SRSF5,PTPRS,0.18465853077237537,destabilizing
+SRSF5,SPDYE3,0.13212670448895258,destabilizing
+SRSF5,TMEM178B,0.06157929000456532,destabilizing
+SRSF5,DMD,0.2026638218540763,destabilizing
+SRSF5,MCU,0.11970586341778344,destabilizing
+SRSF5,SSH2,0.12077460664424208,destabilizing
+SRSF5,DOCK3,0.1568399255860237,destabilizing
+SRSF5,HS6ST3,0.15882204188139154,destabilizing
+SRSF5,LPP,0.1783281511553963,destabilizing
+SRSF5,STAG1,0.12130008961616241,destabilizing
+SRSF5,CAPZA2,0.14219685376665228,destabilizing
+SRSF5,ADGRL3,0.06648121199795008,destabilizing
+SRSF5,UBE2R2,0.15290897189206606,destabilizing
+SRSF5,GTF2IRD1,0.13525197776764988,destabilizing
+SRSF5,CCBE1,0.05623103886808766,destabilizing
+SRSF5,TTC28,0.08631181128184283,destabilizing
+SRSF5,SBNO1,0.06409613029728936,destabilizing
+SRSF5,RIMS2,0.08547540133375965,destabilizing
+SRSF5,IGF1R,0.05908357998843098,destabilizing
+SRSF5,TRIO,0.05941861837160039,destabilizing
+SRSF5,BTBD9,0.13722010123870135,destabilizing
+SRSF5,CNGB1,0.18284965415235857,destabilizing
+SRSF5,FMN2,0.11413867994020166,destabilizing
+SRSF5,ENSG00000228222,0.2042749658952984,destabilizing
+SRSF5,PRKN,0.16213032785099551,destabilizing
+SRSF5,RASA2,0.15556660521153662,destabilizing
+SRSF5,PPP1R12B,0.08359973244226228,destabilizing
+SRSF5,FRMD4A,0.09882804913006238,destabilizing
+SRSF5,SEMA6D,0.09390156901520144,destabilizing
+SRSF5,WIPF2,0.1283035625915495,destabilizing
+SRSF5,DLEU1,0.21529494812327984,destabilizing
+SRSF5,TSHZ2,0.08303918264404866,destabilizing
+SRSF5,MED13L,0.07180213449399152,destabilizing
+SRSF5,KAZN,0.11630223087622212,destabilizing
+SRSF5,KANSL1,0.07334479454915749,destabilizing
+SRSF5,FRMD5,0.11804381934190677,destabilizing
+SRSF5,LINC00174,0.13137785727936716,destabilizing
+SRSF5,PPM1E,0.11517697707533982,destabilizing
+SRSF5,ARL3,0.09567945191490199,destabilizing
+SRSF5,MBD5,0.09252279603812592,destabilizing
+SRSF5,ELAVL3,0.13475401953265095,destabilizing
+SRSF5,SLIT2,0.20891182584188348,destabilizing
+SRSF5,CLASP1,0.07626020980608,destabilizing
+SRSF5,UNC5C,0.152554944048964,destabilizing
+SRSF5,CACNA2D3,-0.06033990006659017,stabilizing
+SRSF5,RC3H1,0.07952235868338293,destabilizing
+SRSF5,NEGR1,0.1348136758252906,destabilizing
+SRSF5,ENOX1,0.20216641956168774,destabilizing
+SRSF5,SCUBE1,0.09569938972980815,destabilizing
+SRSF5,GPHN,0.09897450672577311,destabilizing
+SRSF5,NAV3,0.17215456117379438,destabilizing
+SRSF5,TOMM22,0.16791033733350033,destabilizing
+SRSF5,LSAMP,0.09346830095939693,destabilizing
+SRSF5,AKAP6,0.12640254795673062,destabilizing
+SRSF5,TMED2,0.08202263709035006,destabilizing
+SRSF5,ZBTB20,0.11120591985118619,destabilizing
+SRSF5,GRIK2,0.12673975051978323,destabilizing
+SRSF5,SOX5,0.09186066093367212,destabilizing
+SRSF5,LRRC37A3,0.18824302067872,destabilizing
+SRSF5,EYS,0.09700237924215009,destabilizing
+SRSF5,ARID1B,0.09816021076097166,destabilizing
+SRSF5,PRKCE,0.07614270043542605,destabilizing
+SRSF5,RBFOX1,-0.09900372915682851,stabilizing
+SRSF5,SDK1,0.0673666942476659,destabilizing
+SRSF5,MLLT3,0.22425353737615594,destabilizing
+SRSF5,FMN1,0.060134164257993825,destabilizing
+SRSF5,ADGRB3,0.08986732993866434,destabilizing
+SRSF5,ROBO1,0.12743300005170005,destabilizing
+SRSF5,SYPL1,0.06382208370731833,destabilizing
+SRSF5,PTPRD,0.11622013015906628,destabilizing
+SRSF5,FAM155A,0.1624212030496499,destabilizing
+SRSF5,LARP1B,0.12509650552493612,destabilizing
+SRSF7,TRERF1,0.1572654955957037,destabilizing
+SRSF7,SORCS1,0.12557953308734052,destabilizing
+SRSF7,NCOA1,0.05928195127056332,destabilizing
+SRSF7,FCHSD2,0.10460149326388136,destabilizing
+SRSF7,PDE3A,0.15149590207387728,destabilizing
+SRSF7,UNC79,0.2184488897941353,destabilizing
+SRSF7,DOC2B,0.13281965407008803,destabilizing
+SRSF7,TMTC2,0.19196382070883047,destabilizing
+SRSF7,KALRN,0.14280740891079827,destabilizing
+SRSF7,CHD1,0.09325606820488627,destabilizing
+SRSF7,UBE2E2,0.0735107411949788,destabilizing
+SRSF7,PPARD,0.12041661974031409,destabilizing
+SRSF7,TOX,0.110937186967764,destabilizing
+SRSF7,BRAF,0.07842688241923348,destabilizing
+SRSF7,RYR2,0.18467211497755226,destabilizing
+SRSF7,MTMR7,0.21263539071695417,destabilizing
+SRSF7,EIF4E,0.23918830420281387,destabilizing
+SRSF7,SOX11,0.07080504904782768,destabilizing
+SRSF7,EPB41L4B,0.099459884497361,destabilizing
+SRSF7,CACNA1B,0.11151443646074216,destabilizing
+SRSF7,WSB1,0.0676261358081825,destabilizing
+SRSF7,LRRTM4,0.10268712468952089,destabilizing
+SRSF7,SIRPA,0.1383545740156962,destabilizing
+SRSF7,PTEN,0.11926252067121083,destabilizing
+SRSF7,FRY,0.21889195223178923,destabilizing
+SRSF7,RUNX1T1,0.073534356544689,destabilizing
+SRSF7,MACROD2,0.19694180484982185,destabilizing
+SRSF7,SHANK2,0.24681505024930164,destabilizing
+SRSF7,CDK12,0.28719343284557497,destabilizing
+SRSF7,BMPR1B,0.04968942280767033,destabilizing
+SRSF7,RFX7,0.15535996932765003,destabilizing
+SRSF7,UBR5,0.07902343694169703,destabilizing
+SRSF7,JARID2,0.09229051181744759,destabilizing
+SRSF7,MPHOSPH8,0.16385762034390078,destabilizing
+SRSF7,DIP2C,0.11894804536751648,destabilizing
+SRSF7,ZNF423,0.0832658010210454,destabilizing
+SRSF7,UBR3,0.11483284696497444,destabilizing
+SRSF7,MGAT5,0.050815539005109316,destabilizing
+SRSF7,DLG2,0.10793814794111771,destabilizing
+SRSF7,CHST12,0.2976274199711856,destabilizing
+SRSF7,EML5,0.20326817200125974,destabilizing
+SRSF7,CENPP,0.35764031129206075,destabilizing
+SRSF7,PSME4,0.17533918504293225,destabilizing
+SRSF7,TMEM106B,0.1503586754639621,destabilizing
+SRSF7,RABGAP1L,0.08506405287522215,destabilizing
+SRSF7,EPHA5,0.1268789579269287,destabilizing
+SRSF7,KCNB2,0.24100016159685378,destabilizing
+SRSF7,ZNF83,0.1615512069747551,destabilizing
+SRSF7,SOX6,0.13331672703088096,destabilizing
+SRSF7,ZNF521,0.17336227572971136,destabilizing
+SRSF7,PLEKHA5,0.11497147040538006,destabilizing
+SRSF7,NOVA1,0.20846664456970518,destabilizing
+SRSF7,CCNY,0.19926811299149075,destabilizing
+SRSF7,ARIH1,0.12286423768957194,destabilizing
+SRSF7,EPB41L5,0.09639387077712744,destabilizing
+SRSF7,GPR158,0.15428126716140267,destabilizing
+SRSF7,NCOA2,0.092317381710021,destabilizing
+SRSF7,MARCKS,0.06748571187694248,destabilizing
+SRSF7,ALK,0.30079437760933675,destabilizing
+SRSF7,ARHGAP26,0.06575277453392354,destabilizing
+SRSF7,CTNND2,0.06643647842822181,destabilizing
+SRSF7,IFT172,0.17879251450732145,destabilizing
+SRSF7,CCNT1,0.11936442760160007,destabilizing
+SRSF7,DTWD2,0.2829929458357405,destabilizing
+SRSF7,SIK3,0.1656145287166811,destabilizing
+SRSF7,CPEB3,0.18709157783932898,destabilizing
+SRSF7,CADM2,0.11368841334089928,destabilizing
+SRSF7,XKR6,0.20876246317767178,destabilizing
+SRSF7,RMND5A,0.06295409741349654,destabilizing
+SRSF7,CADPS,0.11132757858668937,destabilizing
+SRSF7,FGF13,0.09323374698216147,destabilizing
+SRSF7,TCF20,0.14528169635543228,destabilizing
+SRSF7,CDKAL1,0.12177813377244455,destabilizing
+SRSF7,DGKI,0.1481798895448952,destabilizing
+SRSF7,EXOC6B,0.2042943387462103,destabilizing
+SRSF7,MAGI3,0.2019673501783391,destabilizing
+SRSF7,SBF2,0.09593327702989772,destabilizing
+SRSF7,INPP4B,0.12988267346595547,destabilizing
+SRSF7,PTPRS,0.1759362112966076,destabilizing
+SRSF7,CBFA2T2,0.07431975626732928,destabilizing
+SRSF7,SPDYE3,0.11021706823141603,destabilizing
+SRSF7,TMEM178B,0.09984124553463357,destabilizing
+SRSF7,DMD,0.2621552165843023,destabilizing
+SRSF7,EIF4G3,0.09276108924457453,destabilizing
+SRSF7,MCU,0.15196440446987958,destabilizing
+SRSF7,SSH2,0.13075350774015623,destabilizing
+SRSF7,DOCK3,0.22717422732958445,destabilizing
+SRSF7,HS6ST3,0.10175990471247105,destabilizing
+SRSF7,LPP,0.1251593945247833,destabilizing
+SRSF7,STAG1,0.1554218535162404,destabilizing
+SRSF7,CAPZA2,0.16476321182455303,destabilizing
+SRSF7,ADGRL3,0.09338451685030794,destabilizing
+SRSF7,PHACTR1,0.10648985002237697,destabilizing
+SRSF7,UBE2R2,0.18064563805300451,destabilizing
+SRSF7,GTF2IRD1,0.11293282027056568,destabilizing
+SRSF7,FTX,0.06336297043992818,destabilizing
+SRSF7,TTC28,0.14064646282137894,destabilizing
+SRSF7,SBNO1,0.0830169722859288,destabilizing
+SRSF7,RIMS2,0.13279773962764793,destabilizing
+SRSF7,IGF1R,0.05935315236474795,destabilizing
+SRSF7,BTBD9,0.13692247642154365,destabilizing
+SRSF7,CNGB1,0.1896360423731489,destabilizing
+SRSF7,FMN2,0.12608758191654315,destabilizing
+SRSF7,ENSG00000228222,0.2392220027494936,destabilizing
+SRSF7,ATXN1,0.07284584685841511,destabilizing
+SRSF7,SYN3,0.07313410383289347,destabilizing
+SRSF7,PRKN,0.14773342417242374,destabilizing
+SRSF7,RASA2,0.21221620717331507,destabilizing
+SRSF7,PPP1R12B,0.10540465120447172,destabilizing
+SRSF7,FRMD4A,0.1162795725657958,destabilizing
+SRSF7,CAMK1D,0.06252511474476781,destabilizing
+SRSF7,SEMA6D,0.1505533741996382,destabilizing
+SRSF7,WIPF2,0.2009504013392185,destabilizing
+SRSF7,DLEU1,0.20778026387295143,destabilizing
+SRSF7,TSHZ2,0.10425553273087622,destabilizing
+SRSF7,MED13L,0.10057811093711391,destabilizing
+SRSF7,KAZN,0.1368772367185814,destabilizing
+SRSF7,KANSL1,0.10968437450603255,destabilizing
+SRSF7,FRMD5,0.13030875593042304,destabilizing
+SRSF7,LINC00174,0.20267119834232147,destabilizing
+SRSF7,PPM1E,0.12966245208536695,destabilizing
+SRSF7,ARL3,0.1311710904573711,destabilizing
+SRSF7,MBD5,0.153735689476669,destabilizing
+SRSF7,ELAVL3,0.17571323522017024,destabilizing
+SRSF7,SLIT2,0.18335154210825919,destabilizing
+SRSF7,CLASP1,0.11867113555284413,destabilizing
+SRSF7,UNC5C,0.1702324012651578,destabilizing
+SRSF7,CACNA2D3,-0.05736468322842808,stabilizing
+SRSF7,RC3H1,0.07021136373825934,destabilizing
+SRSF7,NEGR1,0.18886911471936935,destabilizing
+SRSF7,ENOX1,0.21540824870544273,destabilizing
+SRSF7,SCUBE1,0.09769619568109097,destabilizing
+SRSF7,GPHN,0.0978230433477959,destabilizing
+SRSF7,NAV3,0.18879544737505663,destabilizing
+SRSF7,EBF1,0.06510989886998025,destabilizing
+SRSF7,TOMM22,0.19976207338941857,destabilizing
+SRSF7,MBNL2,0.07617628176526901,destabilizing
+SRSF7,ANKFN1,0.08066835111706724,destabilizing
+SRSF7,MAGI2,0.0810249879701358,destabilizing
+SRSF7,LSAMP,0.11927976095959995,destabilizing
+SRSF7,AKAP6,0.16151663106721134,destabilizing
+SRSF7,TMED2,0.13934919375296032,destabilizing
+SRSF7,ZBTB20,0.134744489357288,destabilizing
+SRSF7,GRIK2,0.14162481749142167,destabilizing
+SRSF7,SOX5,0.10617616125654646,destabilizing
+SRSF7,LRRC37A3,0.2413414533870466,destabilizing
+SRSF7,TMEM132C,0.06385984810820727,destabilizing
+SRSF7,EYS,0.12012082141811589,destabilizing
+SRSF7,ARID1B,0.12089036086567602,destabilizing
+SRSF7,PRKCE,0.11604341026413306,destabilizing
+SRSF7,RBFOX1,-0.09488049535990874,stabilizing
+SRSF7,SDK1,0.10554939620190468,destabilizing
+SRSF7,NRG1,0.05480064235470268,destabilizing
+SRSF7,RORA,0.056962527008541354,destabilizing
+SRSF7,MLLT3,0.2720985883826557,destabilizing
+SRSF7,FMN1,0.0868506450242517,destabilizing
+SRSF7,ADGRB3,0.08151550376949981,destabilizing
+SRSF7,ROBO1,0.1328147429341158,destabilizing
+SRSF7,SYPL1,0.09979175970920501,destabilizing
+SRSF7,PTPRD,0.15475502737109084,destabilizing
+SRSF7,FAM155A,0.17288488370943295,destabilizing
+SRSF7,LARP1B,0.1295341431743208,destabilizing
+SRSF9,TRERF1,0.3002075047971791,destabilizing
+SRSF9,SORCS1,0.1943431040303029,destabilizing
+SRSF9,NCOA1,0.08760334235357574,destabilizing
+SRSF9,COPA,0.13663048214078805,destabilizing
+SRSF9,FCHSD2,0.1320422083883396,destabilizing
+SRSF9,PDE3A,0.2466502120389638,destabilizing
+SRSF9,UNC79,0.29549845515303863,destabilizing
+SRSF9,DOC2B,0.19126916994299797,destabilizing
+SRSF9,TMTC2,0.25891740336171304,destabilizing
+SRSF9,KALRN,0.2035122814784687,destabilizing
+SRSF9,CHD1,0.14347535830102998,destabilizing
+SRSF9,PAK3,0.07707399211335385,destabilizing
+SRSF9,UBE2E2,0.12618275550302122,destabilizing
+SRSF9,PPARD,0.1741654517267921,destabilizing
+SRSF9,TOX,0.11069956360094726,destabilizing
+SRSF9,BRAF,0.12467082524435939,destabilizing
+SRSF9,RYR2,0.2719915662700261,destabilizing
+SRSF9,MTMR7,0.3054029837287622,destabilizing
+SRSF9,EIF4E,0.2850689087243856,destabilizing
+SRSF9,SOX11,0.07934745411879121,destabilizing
+SRSF9,EPB41L4B,0.16536492272468428,destabilizing
+SRSF9,CACNA1B,0.15727859162532262,destabilizing
+SRSF9,TBC1D5,0.11356690862752833,destabilizing
+SRSF9,WSB1,0.06668766594990008,destabilizing
+SRSF9,LRRTM4,0.16520302066317336,destabilizing
+SRSF9,SIRPA,0.15193041104936242,destabilizing
+SRSF9,PTEN,0.1837972488092515,destabilizing
+SRSF9,SPPL3,0.05842097161876749,destabilizing
+SRSF9,FRY,0.29140164547759667,destabilizing
+SRSF9,RUNX1T1,0.08518479918862708,destabilizing
+SRSF9,MACROD2,0.2581908922420794,destabilizing
+SRSF9,FOXN3,0.099405522368528,destabilizing
+SRSF9,SHANK2,0.32782744542067216,destabilizing
+SRSF9,CDK12,0.3211647430242524,destabilizing
+SRSF9,RFX7,0.2648500856724323,destabilizing
+SRSF9,UBR5,0.11559924822963427,destabilizing
+SRSF9,JARID2,0.14731515422173652,destabilizing
+SRSF9,MPHOSPH8,0.22075480923639085,destabilizing
+SRSF9,DIP2C,0.18051452927329412,destabilizing
+SRSF9,ZNF423,0.10867140254917686,destabilizing
+SRSF9,UBR3,0.20236194237183552,destabilizing
+SRSF9,MGAT5,0.08058796957279475,destabilizing
+SRSF9,DLG2,0.17230844312431023,destabilizing
+SRSF9,CHST12,0.3998337030546059,destabilizing
+SRSF9,EML5,0.30621145080319623,destabilizing
+SRSF9,CENPP,0.3557312549765216,destabilizing
+SRSF9,PSME4,0.24660994325578375,destabilizing
+SRSF9,TMEM106B,0.2513485576523856,destabilizing
+SRSF9,RABGAP1L,0.08581162380175598,destabilizing
+SRSF9,EPHA5,0.2003672480735621,destabilizing
+SRSF9,KCNB2,0.3198907930716636,destabilizing
+SRSF9,ZNF83,0.16899339554742376,destabilizing
+SRSF9,SOX6,0.16587143171077218,destabilizing
+SRSF9,ZNF521,0.22983636236143806,destabilizing
+SRSF9,PLEKHA5,0.16999209129418646,destabilizing
+SRSF9,NOVA1,0.29201002382288344,destabilizing
+SRSF9,CCNY,0.2229675379470766,destabilizing
+SRSF9,ARIH1,0.20824786183652982,destabilizing
+SRSF9,FAM171B,0.06548153474765997,destabilizing
+SRSF9,EPB41L5,0.1732867250324034,destabilizing
+SRSF9,GPR158,0.2602771821637321,destabilizing
+SRSF9,NCOA2,0.17675406221331527,destabilizing
+SRSF9,PRKCB,0.05841494536320602,destabilizing
+SRSF9,ALK,0.3470826121670856,destabilizing
+SRSF9,ACACA,0.10298300774820028,destabilizing
+SRSF9,ARHGAP26,0.10151850055821017,destabilizing
+SRSF9,CTNND2,0.12156676797609647,destabilizing
+SRSF9,IFT172,0.24000237853375103,destabilizing
+SRSF9,CCNT1,0.16360805568853604,destabilizing
+SRSF9,DTWD2,0.3474995634440101,destabilizing
+SRSF9,SIK3,0.23914455117826336,destabilizing
+SRSF9,CPEB3,0.26534183374351084,destabilizing
+SRSF9,CADM2,0.11239545180276721,destabilizing
+SRSF9,XKR6,0.2899616381464741,destabilizing
+SRSF9,RMND5A,0.08592144565919585,destabilizing
+SRSF9,CADPS,0.15029822923203567,destabilizing
+SRSF9,FGF13,0.11966371438449938,destabilizing
+SRSF9,TCF20,0.22692565686120703,destabilizing
+SRSF9,CDKAL1,0.18639027353276638,destabilizing
+SRSF9,DGKI,0.217064914890427,destabilizing
+SRSF9,EXOC6B,0.3053320305963325,destabilizing
+SRSF9,MAGI3,0.2516082972227251,destabilizing
+SRSF9,SBF2,0.14676882215041193,destabilizing
+SRSF9,INPP4B,0.19713445863868,destabilizing
+SRSF9,ERC1,0.09608669655973529,destabilizing
+SRSF9,PTPRS,0.20017519173796305,destabilizing
+SRSF9,CBFA2T2,0.13666313308147504,destabilizing
+SRSF9,SPDYE3,0.18821567781364767,destabilizing
+SRSF9,TMEM178B,0.14943261419709117,destabilizing
+SRSF9,KMT2C,0.08589962681115212,destabilizing
+SRSF9,CACNA2D1,0.06467112078507246,destabilizing
+SRSF9,DMD,0.3827253633409557,destabilizing
+SRSF9,EIF4G3,0.09658927991300556,destabilizing
+SRSF9,MCU,0.2267163181689885,destabilizing
+SRSF9,SSH2,0.20302022986690219,destabilizing
+SRSF9,DOCK3,0.2873293902664016,destabilizing
+SRSF9,HS6ST3,0.1990661210817766,destabilizing
+SRSF9,LPP,0.23125208551562867,destabilizing
+SRSF9,STAG1,0.17560060889990323,destabilizing
+SRSF9,CAPZA2,0.23698000720219234,destabilizing
+SRSF9,ADGRL3,0.12308249054639991,destabilizing
+SRSF9,PHACTR1,0.14666836297747068,destabilizing
+SRSF9,UBE2R2,0.24362928606340387,destabilizing
+SRSF9,GTF2IRD1,0.18440044292559057,destabilizing
+SRSF9,CCBE1,0.13222704104205812,destabilizing
+SRSF9,FTX,0.07692807585276037,destabilizing
+SRSF9,VAPA,0.05838844243040137,destabilizing
+SRSF9,JMJD1C,0.08398069124448497,destabilizing
+SRSF9,TTC28,0.18746162151215834,destabilizing
+SRSF9,SBNO1,0.12785904422187203,destabilizing
+SRSF9,RIMS2,0.17224104083308658,destabilizing
+SRSF9,IGF1R,0.10090478546827994,destabilizing
+SRSF9,TRIO,0.09519944155154232,destabilizing
+SRSF9,KCND2,0.08636987400272315,destabilizing
+SRSF9,BTBD9,0.20579346166776125,destabilizing
+SRSF9,CNGB1,0.27479434573403777,destabilizing
+SRSF9,FMN2,0.19997231023779188,destabilizing
+SRSF9,ENSG00000228222,0.3553694088273562,destabilizing
+SRSF9,ATXN1,0.10087098890772526,destabilizing
+SRSF9,SYN3,0.09735132469397043,destabilizing
+SRSF9,PRKN,0.2499978053766029,destabilizing
+SRSF9,RASA2,0.2677554436770194,destabilizing
+SRSF9,PPP1R12B,0.13601021820030984,destabilizing
+SRSF9,FRMD4A,0.18163566586316235,destabilizing
+SRSF9,CAMK1D,0.10185948090114269,destabilizing
+SRSF9,PARD3,0.08401040852057733,destabilizing
+SRSF9,SEMA6D,0.23558137840781124,destabilizing
+SRSF9,WIPF2,0.2359937445394635,destabilizing
+SRSF9,DLEU1,0.2999230972099433,destabilizing
+SRSF9,TSHZ2,0.13578874678146388,destabilizing
+SRSF9,MED13L,0.14957761379402343,destabilizing
+SRSF9,AFF3,0.06025768683093051,destabilizing
+SRSF9,KAZN,0.22557570425608933,destabilizing
+SRSF9,KANSL1,0.1682774926546682,destabilizing
+SRSF9,FRMD5,0.20280660952917737,destabilizing
+SRSF9,LINC00174,0.2312636153229849,destabilizing
+SRSF9,PPM1E,0.2031406398136056,destabilizing
+SRSF9,ARL3,0.16701187493208886,destabilizing
+SRSF9,MBD5,0.21343790808946914,destabilizing
+SRSF9,ELAVL3,0.2252881790034311,destabilizing
+SRSF9,SLIT2,0.2936767738277503,destabilizing
+SRSF9,SLC8A1,0.08036965152997838,destabilizing
+SRSF9,CLASP1,0.17637699013248634,destabilizing
+SRSF9,DOCK4,0.057890600475460983,destabilizing
+SRSF9,UNC5C,0.22409222939127776,destabilizing
+SRSF9,CACNA2D3,-0.09740992953425069,stabilizing
+SRSF9,RC3H1,0.147203001979993,destabilizing
+SRSF9,NEGR1,0.2593300048589185,destabilizing
+SRSF9,ENOX1,0.3212194069247163,destabilizing
+SRSF9,SCUBE1,0.13051148765012083,destabilizing
+SRSF9,GPHN,0.14776102050533257,destabilizing
+SRSF9,NAV3,0.2483175072357455,destabilizing
+SRSF9,EBF1,0.10797637484938277,destabilizing
+SRSF9,TOMM22,0.283914396155244,destabilizing
+SRSF9,MBNL2,0.13192481614417814,destabilizing
+SRSF9,ANKFN1,0.10446867262999306,destabilizing
+SRSF9,MAGI2,0.12186530313642356,destabilizing
+SRSF9,LSAMP,0.1542317534400521,destabilizing
+SRSF9,AKAP6,0.25007039601952896,destabilizing
+SRSF9,TMED2,0.17769620064681915,destabilizing
+SRSF9,ZBTB20,0.21408494474429166,destabilizing
+SRSF9,GRIK2,0.20931553671431244,destabilizing
+SRSF9,SOX5,0.17543022862460145,destabilizing
+SRSF9,LRRC37A3,0.3309883657680359,destabilizing
+SRSF9,TMEM132C,0.09452996257848026,destabilizing
+SRSF9,EYS,0.1687973888124104,destabilizing
+SRSF9,ARID1B,0.17047573096769392,destabilizing
+SRSF9,PRKCE,0.16253352309190922,destabilizing
+SRSF9,RBFOX1,-0.09689136531653589,stabilizing
+SRSF9,SDK1,0.13579590668439628,destabilizing
+SRSF9,NRG1,0.10798976720946045,destabilizing
+SRSF9,RORA,0.08182857155509396,destabilizing
+SRSF9,MLLT3,0.3436787683593404,destabilizing
+SRSF9,FMN1,0.1767827603906393,destabilizing
+SRSF9,ADGRB3,0.14332586873543957,destabilizing
+SRSF9,ROBO1,0.18003991858697643,destabilizing
+SRSF9,SYPL1,0.14577649451172425,destabilizing
+SRSF9,PTPRD,0.20596440053800788,destabilizing
+SRSF9,FAM155A,0.24508213423521136,destabilizing
+SRSF9,LARP1B,0.20780543906379326,destabilizing
+SRSF10,TRERF1,0.11297199611402624,destabilizing
+SRSF10,SORCS1,0.10458543667565219,destabilizing
+SRSF10,PDE3A,0.12394252710460782,destabilizing
+SRSF10,UNC79,0.14549380196828213,destabilizing
+SRSF10,DOC2B,0.1052857934258526,destabilizing
+SRSF10,TMTC2,0.14361600609595518,destabilizing
+SRSF10,KALRN,0.10372831379029969,destabilizing
+SRSF10,CHD1,0.0704435188872733,destabilizing
+SRSF10,UBE2E2,0.07686765248476135,destabilizing
+SRSF10,PPARD,0.11765150380352805,destabilizing
+SRSF10,RYR2,0.12992141968745352,destabilizing
+SRSF10,MTMR7,0.16723659317312628,destabilizing
+SRSF10,EIF4E,0.1525656757815876,destabilizing
+SRSF10,EPB41L4B,0.07196831245843752,destabilizing
+SRSF10,CACNA1B,0.07855214366038499,destabilizing
+SRSF10,LRRTM4,0.07919321016905569,destabilizing
+SRSF10,SIRPA,0.10294597770333153,destabilizing
+SRSF10,PTEN,0.08363652026129649,destabilizing
+SRSF10,FRY,0.17526409466252346,destabilizing
+SRSF10,MACROD2,0.14477661697901686,destabilizing
+SRSF10,SHANK2,0.16704175827343026,destabilizing
+SRSF10,CDK12,0.22884801955312056,destabilizing
+SRSF10,RFX7,0.15991568760287714,destabilizing
+SRSF10,MPHOSPH8,0.12330353434044461,destabilizing
+SRSF10,DIP2C,0.08192412801200123,destabilizing
+SRSF10,UBR3,0.07974222499466281,destabilizing
+SRSF10,DLG2,0.12060045553874044,destabilizing
+SRSF10,CHST12,0.24081751588397365,destabilizing
+SRSF10,EML5,0.1573663338176147,destabilizing
+SRSF10,CENPP,0.25302538765908317,destabilizing
+SRSF10,PSME4,0.1263757227120316,destabilizing
+SRSF10,TMEM106B,0.13636239857986937,destabilizing
+SRSF10,EPHA5,0.12165980641101337,destabilizing
+SRSF10,KCNB2,0.1785982370711491,destabilizing
+SRSF10,ZNF83,0.12591215106804374,destabilizing
+SRSF10,SOX6,0.08722138299226831,destabilizing
+SRSF10,ZNF521,0.12497197160686362,destabilizing
+SRSF10,NOVA1,0.17071732522013616,destabilizing
+SRSF10,CCNY,0.1366814221082207,destabilizing
+SRSF10,ARIH1,0.09395586280012931,destabilizing
+SRSF10,EPB41L5,0.07427059800463275,destabilizing
+SRSF10,GPR158,0.12968454229578674,destabilizing
+SRSF10,NCOA2,0.09479219955625458,destabilizing
+SRSF10,ALK,0.1977198204310978,destabilizing
+SRSF10,ACACA,0.05985475710088376,destabilizing
+SRSF10,IFT172,0.13143555634781431,destabilizing
+SRSF10,CCNT1,0.0781289368224618,destabilizing
+SRSF10,DTWD2,0.21751602031715472,destabilizing
+SRSF10,SIK3,0.14205658342003197,destabilizing
+SRSF10,CPEB3,0.13411096333090602,destabilizing
+SRSF10,XKR6,0.14624663165725565,destabilizing
+SRSF10,RMND5A,0.05515062221816588,destabilizing
+SRSF10,CADPS,0.07115904332758503,destabilizing
+SRSF10,TCF20,0.12014247883298179,destabilizing
+SRSF10,CDKAL1,0.08347078224361937,destabilizing
+SRSF10,DGKI,0.11078893623774436,destabilizing
+SRSF10,EXOC6B,0.1632030594427515,destabilizing
+SRSF10,MAGI3,0.1623397405825776,destabilizing
+SRSF10,INPP4B,0.11848727667716699,destabilizing
+SRSF10,PTPRS,0.12397294133449453,destabilizing
+SRSF10,SPDYE3,0.09294432210425259,destabilizing
+SRSF10,TMEM178B,0.06706250207748564,destabilizing
+SRSF10,DMD,0.17556640861302647,destabilizing
+SRSF10,EIF4G3,0.056754902162876035,destabilizing
+SRSF10,MCU,0.1262816604858261,destabilizing
+SRSF10,SSH2,0.1118787471764637,destabilizing
+SRSF10,DOCK3,0.16284059164728426,destabilizing
+SRSF10,HS6ST3,0.1147131913374909,destabilizing
+SRSF10,LPP,0.10850121177462661,destabilizing
+SRSF10,STAG1,0.10202658423357595,destabilizing
+SRSF10,CAPZA2,0.1388262009263301,destabilizing
+SRSF10,PHACTR1,0.07413470671884684,destabilizing
+SRSF10,UBE2R2,0.1200704168035481,destabilizing
+SRSF10,GTF2IRD1,0.09750404681030894,destabilizing
+SRSF10,TTC28,0.08250829122752754,destabilizing
+SRSF10,SBNO1,0.06817767954134671,destabilizing
+SRSF10,RIMS2,0.08757557876955017,destabilizing
+SRSF10,BTBD9,0.119862662032712,destabilizing
+SRSF10,CNGB1,0.1614664254595871,destabilizing
+SRSF10,FMN2,0.09826791619267072,destabilizing
+SRSF10,ENSG00000228222,0.20923024554361822,destabilizing
+SRSF10,SYN3,0.05098633079484978,destabilizing
+SRSF10,PRKN,0.1653013156543998,destabilizing
+SRSF10,RASA2,0.14073171646900923,destabilizing
+SRSF10,PPP1R12B,0.07049229637510633,destabilizing
+SRSF10,FRMD4A,0.09960811314470827,destabilizing
+SRSF10,SEMA6D,0.11228533422884128,destabilizing
+SRSF10,WIPF2,0.14024479412770963,destabilizing
+SRSF10,DLEU1,0.16787611776716377,destabilizing
+SRSF10,TSHZ2,0.07925192281724673,destabilizing
+SRSF10,MED13L,0.07196181665870467,destabilizing
+SRSF10,KAZN,0.10097889085273996,destabilizing
+SRSF10,KANSL1,0.07708026409578736,destabilizing
+SRSF10,FRMD5,0.12424115302687777,destabilizing
+SRSF10,LINC00174,0.129748560743972,destabilizing
+SRSF10,PPM1E,0.09637597796824356,destabilizing
+SRSF10,ARL3,0.08990484958514604,destabilizing
+SRSF10,MBD5,0.07961596795717035,destabilizing
+SRSF10,ELAVL3,0.1293601866462413,destabilizing
+SRSF10,SLIT2,0.17165982119809509,destabilizing
+SRSF10,CLASP1,0.09413553436862582,destabilizing
+SRSF10,UNC5C,0.13089558546947846,destabilizing
+SRSF10,CACNA2D3,-0.05502833623675736,stabilizing
+SRSF10,NEGR1,0.12374091310840632,destabilizing
+SRSF10,ENOX1,0.19422047531407255,destabilizing
+SRSF10,GPHN,0.07934926464563884,destabilizing
+SRSF10,NAV3,0.13996262549489288,destabilizing
+SRSF10,TOMM22,0.16171350210532473,destabilizing
+SRSF10,ANKFN1,0.05496355668136821,destabilizing
+SRSF10,MAGI2,0.054684538679146695,destabilizing
+SRSF10,LSAMP,0.07761527831819946,destabilizing
+SRSF10,AKAP6,0.11969921818406307,destabilizing
+SRSF10,TMED2,0.08451898330362728,destabilizing
+SRSF10,ZBTB20,0.12324211744831964,destabilizing
+SRSF10,GRIK2,0.10525018500999832,destabilizing
+SRSF10,SOX5,0.0764916973530279,destabilizing
+SRSF10,LRRC37A3,0.1626785669433459,destabilizing
+SRSF10,EYS,0.09980981547417325,destabilizing
+SRSF10,ARID1B,0.07201149525014597,destabilizing
+SRSF10,PRKCE,0.08688827572547737,destabilizing
+SRSF10,RBFOX1,-0.07927151852191987,stabilizing
+SRSF10,MLLT3,0.19645623225722753,destabilizing
+SRSF10,FMN1,0.06500938053006967,destabilizing
+SRSF10,ADGRB3,0.05922479993335958,destabilizing
+SRSF10,ROBO1,0.08459535208970069,destabilizing
+SRSF10,SYPL1,0.08058860502612215,destabilizing
+SRSF10,PTPRD,0.11140302527901336,destabilizing
+SRSF10,FAM155A,0.12410001330331358,destabilizing
+SRSF10,LARP1B,0.1130301827486705,destabilizing
+SRSF11,TRERF1,0.17968510589046469,destabilizing
+SRSF11,SORCS1,0.14501939119152893,destabilizing
+SRSF11,NCOA1,0.05627225372047838,destabilizing
+SRSF11,COPA,0.06266942115661986,destabilizing
+SRSF11,FCHSD2,0.09236366911213398,destabilizing
+SRSF11,PDE3A,0.19515172539673625,destabilizing
+SRSF11,UNC79,0.2004969657431988,destabilizing
+SRSF11,DOC2B,0.1207671588750881,destabilizing
+SRSF11,TMTC2,0.1624514105122122,destabilizing
+SRSF11,KALRN,0.14079725280066135,destabilizing
+SRSF11,CHD1,0.10388290748171763,destabilizing
+SRSF11,UBE2E2,0.07062922919472026,destabilizing
+SRSF11,PPARD,0.09227436185795937,destabilizing
+SRSF11,BRAF,0.05829555455411859,destabilizing
+SRSF11,RYR2,0.14449966087933516,destabilizing
+SRSF11,MTMR7,0.17400327841232854,destabilizing
+SRSF11,EIF4E,0.1897807100426119,destabilizing
+SRSF11,SOX11,0.06734366691065007,destabilizing
+SRSF11,EPB41L4B,0.130736592582858,destabilizing
+SRSF11,CACNA1B,0.12067060328328923,destabilizing
+SRSF11,TBC1D5,0.060798850443879435,destabilizing
+SRSF11,LRRTM4,0.13323315188675763,destabilizing
+SRSF11,SIRPA,0.16028350371127184,destabilizing
+SRSF11,PTEN,0.1339012480754207,destabilizing
+SRSF11,FRY,0.19372180516836324,destabilizing
+SRSF11,MACROD2,0.146374732450215,destabilizing
+SRSF11,SHANK2,0.21588932439752131,destabilizing
+SRSF11,CDK12,0.2510499831039094,destabilizing
+SRSF11,RFX7,0.1778527405375971,destabilizing
+SRSF11,UBR5,0.07336001245689538,destabilizing
+SRSF11,JARID2,0.09547298989615685,destabilizing
+SRSF11,MPHOSPH8,0.15469899383390706,destabilizing
+SRSF11,DIP2C,0.1279490632409551,destabilizing
+SRSF11,ZNF423,0.058521485820561985,destabilizing
+SRSF11,UBR3,0.134476080899526,destabilizing
+SRSF11,MGAT5,0.08021487136880105,destabilizing
+SRSF11,DLG2,0.09431740052680547,destabilizing
+SRSF11,CHST12,0.26703614469973513,destabilizing
+SRSF11,EML5,0.1857110866267536,destabilizing
+SRSF11,CENPP,0.20460643388498792,destabilizing
+SRSF11,PSME4,0.1789611750814506,destabilizing
+SRSF11,TMEM106B,0.21233747502162265,destabilizing
+SRSF11,EPHA5,0.1305857388879252,destabilizing
+SRSF11,KCNB2,0.170162821880757,destabilizing
+SRSF11,ZNF83,0.11947245213480244,destabilizing
+SRSF11,SOX6,0.10180913303940688,destabilizing
+SRSF11,ZNF521,0.15523300958617242,destabilizing
+SRSF11,PLEKHA5,0.10148323005330721,destabilizing
+SRSF11,NOVA1,0.1742158895265404,destabilizing
+SRSF11,CCNY,0.14924109796753116,destabilizing
+SRSF11,ARIH1,0.104076192112288,destabilizing
+SRSF11,FAM171B,0.0542334400280736,destabilizing
+SRSF11,EPB41L5,0.11673760268753572,destabilizing
+SRSF11,GPR158,0.16224023267011295,destabilizing
+SRSF11,NCOA2,0.1351034776664899,destabilizing
+SRSF11,PRKCB,0.05404824951309738,destabilizing
+SRSF11,MARCKS,0.05098622912302044,destabilizing
+SRSF11,ALK,0.16420264129393355,destabilizing
+SRSF11,ACACA,0.06572936423180877,destabilizing
+SRSF11,IFT172,0.15575879301940834,destabilizing
+SRSF11,CCNT1,0.10329014857030691,destabilizing
+SRSF11,DTWD2,0.23602829006321105,destabilizing
+SRSF11,SIK3,0.11941027390585977,destabilizing
+SRSF11,CPEB3,0.231084139839797,destabilizing
+SRSF11,CADM2,0.08970514513003494,destabilizing
+SRSF11,XKR6,0.18733970652293105,destabilizing
+SRSF11,RMND5A,0.06202405319750642,destabilizing
+SRSF11,CADPS,0.08302201309538064,destabilizing
+SRSF11,TCF20,0.15284568614016858,destabilizing
+SRSF11,CDKAL1,0.09595673170641404,destabilizing
+SRSF11,DGKI,0.1285427171102654,destabilizing
+SRSF11,EXOC6B,0.20761282554006216,destabilizing
+SRSF11,MAGI3,0.1778526576772331,destabilizing
+SRSF11,SBF2,0.07278500484706141,destabilizing
+SRSF11,INPP4B,0.15412932030025359,destabilizing
+SRSF11,ERC1,0.07095103325738135,destabilizing
+SRSF11,PTPRS,0.21629751602487726,destabilizing
+SRSF11,CBFA2T2,0.0819437521098121,destabilizing
+SRSF11,SPDYE3,0.14490125458836445,destabilizing
+SRSF11,TMEM178B,0.07483419499925133,destabilizing
+SRSF11,DMD,0.24341949588705972,destabilizing
+SRSF11,EIF4G3,0.05793164845054757,destabilizing
+SRSF11,MCU,0.14450441939142564,destabilizing
+SRSF11,SSH2,0.14317017311178798,destabilizing
+SRSF11,DOCK3,0.22253786614242763,destabilizing
+SRSF11,HS6ST3,0.1949963603480445,destabilizing
+SRSF11,LPP,0.20003749755008254,destabilizing
+SRSF11,STAG1,0.13950183364286897,destabilizing
+SRSF11,CAPZA2,0.1462658334239695,destabilizing
+SRSF11,ADGRL3,0.08887273414468073,destabilizing
+SRSF11,PHACTR1,0.078093626605437,destabilizing
+SRSF11,UBE2R2,0.1739864596653099,destabilizing
+SRSF11,GTF2IRD1,0.13495883896924396,destabilizing
+SRSF11,CCBE1,0.06292185497196,destabilizing
+SRSF11,TTC28,0.13311067159190448,destabilizing
+SRSF11,SBNO1,0.08138351161477075,destabilizing
+SRSF11,RIMS2,0.08223649986032003,destabilizing
+SRSF11,KCND2,0.05984516598308169,destabilizing
+SRSF11,BTBD9,0.1721892694102848,destabilizing
+SRSF11,CNGB1,0.1923500536623006,destabilizing
+SRSF11,FMN2,0.11818744685069502,destabilizing
+SRSF11,ENSG00000228222,0.2517050959484158,destabilizing
+SRSF11,PRKN,0.228354498373988,destabilizing
+SRSF11,RASA2,0.18984417140361187,destabilizing
+SRSF11,PPP1R12B,0.09506936102619262,destabilizing
+SRSF11,FRMD4A,0.11046377854485771,destabilizing
+SRSF11,SEMA6D,0.11296955629892663,destabilizing
+SRSF11,WIPF2,0.1812506315899293,destabilizing
+SRSF11,DLEU1,0.182945499040325,destabilizing
+SRSF11,TSHZ2,0.07950524439756912,destabilizing
+SRSF11,MED13L,0.08070821712128741,destabilizing
+SRSF11,AFF3,0.05519590903760549,destabilizing
+SRSF11,KAZN,0.1429020563562697,destabilizing
+SRSF11,KANSL1,0.08105078972615815,destabilizing
+SRSF11,FRMD5,0.14031423866059312,destabilizing
+SRSF11,LINC00174,0.15831392284384263,destabilizing
+SRSF11,PPM1E,0.13819101583760193,destabilizing
+SRSF11,ARL3,0.10896499597046765,destabilizing
+SRSF11,MBD5,0.12608808189449347,destabilizing
+SRSF11,ELAVL3,0.154498596334443,destabilizing
+SRSF11,SLIT2,0.2168677421564966,destabilizing
+SRSF11,CLASP1,0.10093105706179324,destabilizing
+SRSF11,UNC5C,0.13665782939534757,destabilizing
+SRSF11,CACNA2D3,-0.07441965241094636,stabilizing
+SRSF11,RC3H1,0.11448714351389497,destabilizing
+SRSF11,NEGR1,0.16263624596869075,destabilizing
+SRSF11,ENOX1,0.2563094768272628,destabilizing
+SRSF11,SCUBE1,0.10072462694549386,destabilizing
+SRSF11,GPHN,0.1069597040586975,destabilizing
+SRSF11,NAV3,0.1872774215081286,destabilizing
+SRSF11,EBF1,0.06357904678783124,destabilizing
+SRSF11,TOMM22,0.20551455328989396,destabilizing
+SRSF11,ANKFN1,0.06711280583822128,destabilizing
+SRSF11,MAGI2,0.06314648684196965,destabilizing
+SRSF11,LSAMP,0.11129063028091386,destabilizing
+SRSF11,AKAP6,0.16024907284351514,destabilizing
+SRSF11,TMED2,0.1210067143856313,destabilizing
+SRSF11,ZBTB20,0.13331357741853359,destabilizing
+SRSF11,GRIK2,0.14574828422165345,destabilizing
+SRSF11,SOX5,0.08356125225266176,destabilizing
+SRSF11,LRRC37A3,0.19459727122099243,destabilizing
+SRSF11,TMEM132C,0.06505638409775254,destabilizing
+SRSF11,EYS,0.12913035174081244,destabilizing
+SRSF11,ARID1B,0.07986678924863189,destabilizing
+SRSF11,PRKCE,0.09977445664528797,destabilizing
+SRSF11,RBFOX1,-0.0981200624926402,stabilizing
+SRSF11,SDK1,0.08357776122965141,destabilizing
+SRSF11,NRG1,0.06075821711491712,destabilizing
+SRSF11,MLLT3,0.24546306120552297,destabilizing
+SRSF11,FMN1,0.061965334595063544,destabilizing
+SRSF11,ADGRB3,0.08395721476175198,destabilizing
+SRSF11,ROBO1,0.1174776162298886,destabilizing
+SRSF11,SYPL1,0.07783297528344194,destabilizing
+SRSF11,PTPRD,0.14238928721627536,destabilizing
+SRSF11,FAM155A,0.17481536908447365,destabilizing
+SRSF11,LARP1B,0.1673216320822212,destabilizing
+TRA2A,TRERF1,0.13932595280258359,destabilizing
+TRA2A,SORCS1,0.09680198863971348,destabilizing
+TRA2A,PDE3A,0.15168005534760007,destabilizing
+TRA2A,UNC79,0.13660958239946216,destabilizing
+TRA2A,DOC2B,0.09564759559417003,destabilizing
+TRA2A,TMTC2,0.11479157698731364,destabilizing
+TRA2A,KALRN,0.08528126308728833,destabilizing
+TRA2A,CHD1,0.06330195427239134,destabilizing
+TRA2A,UBE2E2,0.0648700704666348,destabilizing
+TRA2A,PPARD,0.08406955812816301,destabilizing
+TRA2A,RYR2,0.11524206104991759,destabilizing
+TRA2A,MTMR7,0.1314578408627951,destabilizing
+TRA2A,SOX11,0.07503280949980319,destabilizing
+TRA2A,CACNA1B,0.07995674312283746,destabilizing
+TRA2A,LRRTM4,0.07820085579942881,destabilizing
+TRA2A,SIRPA,0.12439193647540335,destabilizing
+TRA2A,PTEN,0.08179038441662001,destabilizing
+TRA2A,FRY,0.12198425228627509,destabilizing
+TRA2A,MACROD2,0.0994116683106726,destabilizing
+TRA2A,SHANK2,0.16408709162669768,destabilizing
+TRA2A,CDK12,0.14522819064439144,destabilizing
+TRA2A,RFX7,0.13479712826127982,destabilizing
+TRA2A,UBR5,0.06247300595320576,destabilizing
+TRA2A,JARID2,0.05695916389082925,destabilizing
+TRA2A,MPHOSPH8,0.10559050231918302,destabilizing
+TRA2A,DIP2C,0.08028089905297557,destabilizing
+TRA2A,UBR3,0.1107965959093383,destabilizing
+TRA2A,DLG2,0.08023760092838647,destabilizing
+TRA2A,CHST12,0.2029030669888957,destabilizing
+TRA2A,EML5,0.12637861193907649,destabilizing
+TRA2A,CENPP,0.1482175634292941,destabilizing
+TRA2A,PSME4,0.10121479090761794,destabilizing
+TRA2A,TMEM106B,0.12220451973471218,destabilizing
+TRA2A,EPHA5,0.09136335158838996,destabilizing
+TRA2A,KCNB2,0.15177833064643861,destabilizing
+TRA2A,ZNF83,0.08930104741566576,destabilizing
+TRA2A,SOX6,0.06705377641617097,destabilizing
+TRA2A,ZNF521,0.07850525468279033,destabilizing
+TRA2A,PLEKHA5,0.08194366328851324,destabilizing
+TRA2A,NOVA1,0.16131158782257102,destabilizing
+TRA2A,CCNY,0.116678142755187,destabilizing
+TRA2A,ARIH1,0.08766735798450216,destabilizing
+TRA2A,EPB41L5,0.0752498922972198,destabilizing
+TRA2A,GPR158,0.11258924172812108,destabilizing
+TRA2A,NCOA2,0.06925763076920055,destabilizing
+TRA2A,ALK,0.1208580373849253,destabilizing
+TRA2A,ACACA,0.0869627576433479,destabilizing
+TRA2A,IFT172,0.08778511941588259,destabilizing
+TRA2A,CCNT1,0.05528954626595372,destabilizing
+TRA2A,SIK3,0.09958474632586489,destabilizing
+TRA2A,CPEB3,0.1435053354195212,destabilizing
+TRA2A,XKR6,0.1314936246658197,destabilizing
+TRA2A,CADPS,0.07211739579100224,destabilizing
+TRA2A,TCF20,0.10661372117847136,destabilizing
+TRA2A,CDKAL1,0.08675306637037829,destabilizing
+TRA2A,DGKI,0.0806576948701804,destabilizing
+TRA2A,EXOC6B,0.16658734085064783,destabilizing
+TRA2A,MAGI3,0.13198067491013268,destabilizing
+TRA2A,SBF2,0.06313919830255228,destabilizing
+TRA2A,INPP4B,0.11688946464268728,destabilizing
+TRA2A,SPDYE3,0.10678571021032307,destabilizing
+TRA2A,DMD,0.18453160372890529,destabilizing
+TRA2A,MCU,0.11780275760968217,destabilizing
+TRA2A,SSH2,0.08236327758754472,destabilizing
+TRA2A,DOCK3,0.14063222296093528,destabilizing
+TRA2A,HS6ST3,0.09573030767984754,destabilizing
+TRA2A,LPP,0.11709534811494739,destabilizing
+TRA2A,STAG1,0.10378836830992332,destabilizing
+TRA2A,CAPZA2,0.07791112108168746,destabilizing
+TRA2A,ADGRL3,0.05993147764136796,destabilizing
+TRA2A,PHACTR1,0.06529427469604736,destabilizing
+TRA2A,UBE2R2,0.10266782846429699,destabilizing
+TRA2A,GTF2IRD1,0.12302179957602678,destabilizing
+TRA2A,CCBE1,0.052000438973069184,destabilizing
+TRA2A,TTC28,0.09495322285902885,destabilizing
+TRA2A,RIMS2,0.06552937732260926,destabilizing
+TRA2A,BTBD9,0.12441260396972437,destabilizing
+TRA2A,CNGB1,0.1282387330583066,destabilizing
+TRA2A,FMN2,0.10386894680147939,destabilizing
+TRA2A,ENSG00000228222,0.18958759219523688,destabilizing
+TRA2A,PRKN,0.14973072150461428,destabilizing
+TRA2A,RASA2,0.09268510511908712,destabilizing
+TRA2A,PPP1R12B,0.06492015844581954,destabilizing
+TRA2A,FRMD4A,0.0809177252623519,destabilizing
+TRA2A,SEMA6D,0.07598135118294634,destabilizing
+TRA2A,WIPF2,0.11846011602841075,destabilizing
+TRA2A,DLEU1,0.12772227933959998,destabilizing
+TRA2A,TSHZ2,0.06724459667639258,destabilizing
+TRA2A,MED13L,0.0768269559994957,destabilizing
+TRA2A,KAZN,0.08847642301552702,destabilizing
+TRA2A,FRMD5,0.10549342679388676,destabilizing
+TRA2A,LINC00174,0.07851757800483,destabilizing
+TRA2A,PPM1E,0.09652459930376496,destabilizing
+TRA2A,ARL3,0.0746377636074579,destabilizing
+TRA2A,MBD5,0.09175499425120062,destabilizing
+TRA2A,ELAVL3,0.09575937046953141,destabilizing
+TRA2A,SLIT2,0.1441308840895048,destabilizing
+TRA2A,CLASP1,0.07986980462473746,destabilizing
+TRA2A,UNC5C,0.09308813110492566,destabilizing
+TRA2A,CACNA2D3,-0.07465281553828616,stabilizing
+TRA2A,RC3H1,0.061479918526699734,destabilizing
+TRA2A,NEGR1,0.1506535735914935,destabilizing
+TRA2A,ENOX1,0.14601463636188888,destabilizing
+TRA2A,SCUBE1,0.07491319937063019,destabilizing
+TRA2A,GPHN,0.08606458988110448,destabilizing
+TRA2A,NAV3,0.13575079296332784,destabilizing
+TRA2A,TOMM22,0.12909871232543482,destabilizing
+TRA2A,MAGI2,0.06394511099809563,destabilizing
+TRA2A,LSAMP,0.0670575883990029,destabilizing
+TRA2A,AKAP6,0.10725060498868488,destabilizing
+TRA2A,ZBTB20,0.10308325213474974,destabilizing
+TRA2A,GRIK2,0.0971892001747943,destabilizing
+TRA2A,LRRC37A3,0.1515835647998288,destabilizing
+TRA2A,EYS,0.07460109123353315,destabilizing
+TRA2A,ARID1B,0.0622109785278929,destabilizing
+TRA2A,PRKCE,0.06944805737394963,destabilizing
+TRA2A,RBFOX1,-0.09325444393354357,stabilizing
+TRA2A,MLLT3,0.16294683720777886,destabilizing
+TRA2A,ADGRB3,0.06194240524085506,destabilizing
+TRA2A,ROBO1,0.11194627351188498,destabilizing
+TRA2A,SYPL1,0.06552144030105057,destabilizing
+TRA2A,PTPRD,0.08313615001829601,destabilizing
+TRA2A,FAM155A,0.11485946567354952,destabilizing
+TRA2A,LARP1B,0.12938202049146294,destabilizing
+TRA2B,TRERF1,0.13135429283626537,destabilizing
+TRA2B,SORCS1,0.11805415631205637,destabilizing
+TRA2B,PDE3A,0.1018676610522148,destabilizing
+TRA2B,UNC79,0.17390828934392594,destabilizing
+TRA2B,DOC2B,0.10307197566397011,destabilizing
+TRA2B,TMTC2,0.12863474295581565,destabilizing
+TRA2B,CHD1,0.06497771863610631,destabilizing
+TRA2B,UBE2E2,0.07869071926207681,destabilizing
+TRA2B,PPARD,0.11754016228629591,destabilizing
+TRA2B,TOX,0.07622788109263114,destabilizing
+TRA2B,BRAF,0.05320429901650464,destabilizing
+TRA2B,RYR2,0.12071094648017545,destabilizing
+TRA2B,MTMR7,0.14656252590558258,destabilizing
+TRA2B,EIF4E,0.1385991726032709,destabilizing
+TRA2B,CACNA1B,0.07753598304784905,destabilizing
+TRA2B,LRRTM4,0.09390846941233805,destabilizing
+TRA2B,SIRPA,0.10191475184320813,destabilizing
+TRA2B,PTEN,0.10465886721634582,destabilizing
+TRA2B,FRY,0.15451867999656266,destabilizing
+TRA2B,MACROD2,0.13153890896436107,destabilizing
+TRA2B,SHANK2,0.17855369289204062,destabilizing
+TRA2B,CDK12,0.1884658348149563,destabilizing
+TRA2B,RFX7,0.1237382748355551,destabilizing
+TRA2B,JARID2,0.060896025772729304,destabilizing
+TRA2B,MPHOSPH8,0.11692220909898175,destabilizing
+TRA2B,DIP2C,0.09322703034198118,destabilizing
+TRA2B,UBR3,0.07584489156939062,destabilizing
+TRA2B,DLG2,0.08520686516428932,destabilizing
+TRA2B,CHST12,0.22301224642857254,destabilizing
+TRA2B,EML5,0.16091073863164235,destabilizing
+TRA2B,CENPP,0.27126864755390356,destabilizing
+TRA2B,PSME4,0.13441228155213936,destabilizing
+TRA2B,TMEM106B,0.11626725951527948,destabilizing
+TRA2B,EPHA5,0.10494311397669201,destabilizing
+TRA2B,KCNB2,0.16639665970370837,destabilizing
+TRA2B,ZNF83,0.08747481774807943,destabilizing
+TRA2B,SOX6,0.058901262574914105,destabilizing
+TRA2B,ZNF521,0.11214797141126967,destabilizing
+TRA2B,PLEKHA5,0.06476069579201234,destabilizing
+TRA2B,NOVA1,0.14568101229581246,destabilizing
+TRA2B,CCNY,0.1299222142281019,destabilizing
+TRA2B,ARIH1,0.09726064224214187,destabilizing
+TRA2B,EPB41L5,0.08903745496695158,destabilizing
+TRA2B,GPR158,0.10319692920705062,destabilizing
+TRA2B,ALK,0.2033445640492507,destabilizing
+TRA2B,IFT172,0.13357401790046006,destabilizing
+TRA2B,CCNT1,0.08934876095114512,destabilizing
+TRA2B,DTWD2,0.22224623237885544,destabilizing
+TRA2B,SIK3,0.15612665676213203,destabilizing
+TRA2B,CPEB3,0.11771530081141651,destabilizing
+TRA2B,XKR6,0.14775526593036917,destabilizing
+TRA2B,CADPS,0.07301451698387658,destabilizing
+TRA2B,TCF20,0.1345679030093865,destabilizing
+TRA2B,CDKAL1,0.07407776071896878,destabilizing
+TRA2B,DGKI,0.07967350121840398,destabilizing
+TRA2B,EXOC6B,0.15634294866291942,destabilizing
+TRA2B,MAGI3,0.11868528683945816,destabilizing
+TRA2B,SBF2,0.05722737782810539,destabilizing
+TRA2B,INPP4B,0.08789690931822403,destabilizing
+TRA2B,SPDYE3,0.07487752302573107,destabilizing
+TRA2B,DMD,0.19296717070818592,destabilizing
+TRA2B,MCU,0.13597697080321108,destabilizing
+TRA2B,SSH2,0.10988606086929141,destabilizing
+TRA2B,DOCK3,0.1382718993234176,destabilizing
+TRA2B,HS6ST3,0.09757789382525599,destabilizing
+TRA2B,LPP,0.13948096736483223,destabilizing
+TRA2B,STAG1,0.08204269986330441,destabilizing
+TRA2B,CAPZA2,0.1378234971261477,destabilizing
+TRA2B,PHACTR1,0.0689459322434664,destabilizing
+TRA2B,UBE2R2,0.11906079114370173,destabilizing
+TRA2B,GTF2IRD1,0.07961077906988095,destabilizing
+TRA2B,TTC28,0.09550296600992077,destabilizing
+TRA2B,SBNO1,0.05753490409594311,destabilizing
+TRA2B,RIMS2,0.07628491301475822,destabilizing
+TRA2B,BTBD9,0.11662943090959346,destabilizing
+TRA2B,CNGB1,0.15165171675819059,destabilizing
+TRA2B,FMN2,0.08939567453964554,destabilizing
+TRA2B,ENSG00000228222,0.19950441672695804,destabilizing
+TRA2B,SYN3,0.06654927987920363,destabilizing
+TRA2B,PRKN,0.10978529553422949,destabilizing
+TRA2B,RASA2,0.12452141222853967,destabilizing
+TRA2B,PPP1R12B,0.0965454703203547,destabilizing
+TRA2B,FRMD4A,0.08846459161709361,destabilizing
+TRA2B,SEMA6D,0.09284037481382551,destabilizing
+TRA2B,WIPF2,0.1400960311141215,destabilizing
+TRA2B,DLEU1,0.1587384698231026,destabilizing
+TRA2B,TSHZ2,0.07805848756149877,destabilizing
+TRA2B,KAZN,0.07109934810271827,destabilizing
+TRA2B,KANSL1,0.06718813481620849,destabilizing
+TRA2B,FRMD5,0.09855718253148578,destabilizing
+TRA2B,LINC00174,0.1150633119419222,destabilizing
+TRA2B,ARL3,0.09517803430704878,destabilizing
+TRA2B,MBD5,0.08925558836242058,destabilizing
+TRA2B,ELAVL3,0.1291892100717485,destabilizing
+TRA2B,SLIT2,0.13082944128608376,destabilizing
+TRA2B,CLASP1,0.09795265753111104,destabilizing
+TRA2B,UNC5C,0.1049792077969774,destabilizing
+TRA2B,RC3H1,0.08182302178829369,destabilizing
+TRA2B,NEGR1,0.1342225858360474,destabilizing
+TRA2B,ENOX1,0.17014786048549554,destabilizing
+TRA2B,GPHN,0.08530617530822106,destabilizing
+TRA2B,NAV3,0.13492392315041019,destabilizing
+TRA2B,TOMM22,0.12019375863217491,destabilizing
+TRA2B,LSAMP,0.0743171380381186,destabilizing
+TRA2B,AKAP6,0.12382094736421817,destabilizing
+TRA2B,TMED2,0.06999899101843136,destabilizing
+TRA2B,ZBTB20,0.13982130443892754,destabilizing
+TRA2B,GRIK2,0.07536148300031803,destabilizing
+TRA2B,LRRC37A3,0.17601549210091738,destabilizing
+TRA2B,EYS,0.08007288791729325,destabilizing
+TRA2B,ARID1B,0.0831668009170054,destabilizing
+TRA2B,PRKCE,0.07010300691959906,destabilizing
+TRA2B,RBFOX1,-0.06463808177067834,stabilizing
+TRA2B,MLLT3,0.18768357012845924,destabilizing
+TRA2B,FMN1,0.06280859366010311,destabilizing
+TRA2B,ADGRB3,0.059649292861028005,destabilizing
+TRA2B,ROBO1,0.0732926075906604,destabilizing
+TRA2B,PTPRD,0.10155776230511526,destabilizing
+TRA2B,FAM155A,0.12126472376594918,destabilizing
+TRA2B,LARP1B,0.1163538443942822,destabilizing
+PTBP1,MACROD2,0.07854603660399304,destabilizing
+PTBP1,CDK12,0.1167378099049974,destabilizing
+PTBP1,CENPP,0.16593782822114095,destabilizing
+PTBP1,KCNB2,0.12044789526902101,destabilizing
+PTBP1,ALK,0.15951181185925878,destabilizing
+PTBP1,MCU,0.07622638509764161,destabilizing
+PTBP1,DOCK3,0.08821681766372583,destabilizing
+PTBP1,CAPZA2,0.06636761771772236,destabilizing
+PTBP1,PHACTR1,0.06462934976060399,destabilizing
+PTBP1,RASA2,0.07076667081717893,destabilizing
+PTBP1,WIPF2,0.0717801376100871,destabilizing
+PTBP1,MBD5,0.06193848411710692,destabilizing
+PTBP1,MLLT3,0.08843995909078843,destabilizing
+PTBP1,PTPRD,0.056544618799178874,destabilizing
+PTBP2,TRERF1,0.11163046053129538,destabilizing
+PTBP2,UNC79,0.10047553221655017,destabilizing
+PTBP2,TMTC2,0.10710232015023366,destabilizing
+PTBP2,KALRN,0.06969261881370893,destabilizing
+PTBP2,MTMR7,0.10608698161636763,destabilizing
+PTBP2,EIF4E,0.14815319041084551,destabilizing
+PTBP2,CACNA1B,0.07246998314142541,destabilizing
+PTBP2,LRRTM4,0.07221303702230795,destabilizing
+PTBP2,FRY,0.12045377775516346,destabilizing
+PTBP2,MACROD2,0.08792724426833896,destabilizing
+PTBP2,SHANK2,0.12017413382994038,destabilizing
+PTBP2,CDK12,0.11290048070105128,destabilizing
+PTBP2,RFX7,0.09713573967154833,destabilizing
+PTBP2,MPHOSPH8,0.09226968145649139,destabilizing
+PTBP2,DIP2C,0.07041890210512093,destabilizing
+PTBP2,DLG2,0.08861969992582842,destabilizing
+PTBP2,CHST12,0.1904187349113279,destabilizing
+PTBP2,EML5,0.12097890109305795,destabilizing
+PTBP2,CENPP,0.12571023931993988,destabilizing
+PTBP2,PSME4,0.07148382132624087,destabilizing
+PTBP2,TMEM106B,0.11084135665380512,destabilizing
+PTBP2,EPHA5,0.07866865759545552,destabilizing
+PTBP2,KCNB2,0.12151438356755197,destabilizing
+PTBP2,SOX6,0.06398821206917206,destabilizing
+PTBP2,ZNF521,0.08958191401736205,destabilizing
+PTBP2,PLEKHA5,0.06886160987933221,destabilizing
+PTBP2,ARIH1,0.06326809265124897,destabilizing
+PTBP2,GPR158,0.08464622751010605,destabilizing
+PTBP2,NCOA2,0.0710170243049859,destabilizing
+PTBP2,ALK,0.1274677317932301,destabilizing
+PTBP2,IFT172,0.0848270256317848,destabilizing
+PTBP2,DTWD2,0.1731116467250382,destabilizing
+PTBP2,SIK3,0.07837790930031582,destabilizing
+PTBP2,CPEB3,0.15027601265345156,destabilizing
+PTBP2,XKR6,0.12331833524924045,destabilizing
+PTBP2,EXOC6B,0.10339584935776495,destabilizing
+PTBP2,MAGI3,0.0919982590894658,destabilizing
+PTBP2,INPP4B,0.10347427822436983,destabilizing
+PTBP2,PTPRS,0.11838986101471413,destabilizing
+PTBP2,DMD,0.13979625446847133,destabilizing
+PTBP2,SSH2,0.07809668814296032,destabilizing
+PTBP2,DOCK3,0.10813784459451858,destabilizing
+PTBP2,HS6ST3,0.09387725801980606,destabilizing
+PTBP2,LPP,0.09064283936341795,destabilizing
+PTBP2,CAPZA2,0.10520674534153546,destabilizing
+PTBP2,PHACTR1,0.0652209410171937,destabilizing
+PTBP2,UBE2R2,0.08446095358887441,destabilizing
+PTBP2,GTF2IRD1,0.06281841048404181,destabilizing
+PTBP2,BTBD9,0.09209585331181736,destabilizing
+PTBP2,CNGB1,0.08160046128616515,destabilizing
+PTBP2,FMN2,0.07719775509255825,destabilizing
+PTBP2,ENSG00000228222,0.1537283704786739,destabilizing
+PTBP2,RASA2,0.10407975206725308,destabilizing
+PTBP2,FRMD4A,0.057726420750072095,destabilizing
+PTBP2,SEMA6D,0.09315481504586585,destabilizing
+PTBP2,WIPF2,0.1102742249484477,destabilizing
+PTBP2,DLEU1,0.15243564902843412,destabilizing
+PTBP2,FRMD5,0.0770143713373808,destabilizing
+PTBP2,LINC00174,0.08419030671222275,destabilizing
+PTBP2,PPM1E,0.0733850278730771,destabilizing
+PTBP2,MBD5,0.07867350362776955,destabilizing
+PTBP2,ELAVL3,0.08505639616411298,destabilizing
+PTBP2,SLIT2,0.10906942360040027,destabilizing
+PTBP2,CLASP1,0.0728824239974643,destabilizing
+PTBP2,UNC5C,0.09533795695275796,destabilizing
+PTBP2,NEGR1,0.10732058393763555,destabilizing
+PTBP2,ENOX1,0.13787013439570173,destabilizing
+PTBP2,GPHN,0.07060092705579546,destabilizing
+PTBP2,NAV3,0.11229296541536905,destabilizing
+PTBP2,TOMM22,0.08279669435354095,destabilizing
+PTBP2,LSAMP,0.06059879162195104,destabilizing
+PTBP2,AKAP6,0.068674644707069,destabilizing
+PTBP2,TMED2,0.08242781355839271,destabilizing
+PTBP2,ZBTB20,0.09947359861986126,destabilizing
+PTBP2,GRIK2,0.06898719207898434,destabilizing
+PTBP2,SOX5,0.0664629840807091,destabilizing
+PTBP2,LRRC37A3,0.14405748544980101,destabilizing
+PTBP2,EYS,0.06154006951236333,destabilizing
+PTBP2,ARID1B,0.05807344342656432,destabilizing
+PTBP2,MLLT3,0.12631054386212942,destabilizing
+PTBP2,ROBO1,0.08177860421791995,destabilizing
+PTBP2,SYPL1,0.058146491746619816,destabilizing
+PTBP2,PTPRD,0.06809130130879716,destabilizing
+PTBP2,LARP1B,0.09291824095187702,destabilizing
+PTBP3,SORCS1,0.057365824993070774,destabilizing
+PTBP3,PDE3A,0.0931046669830606,destabilizing
+PTBP3,DOC2B,0.0615108403698913,destabilizing
+PTBP3,TMTC2,0.07866388789183568,destabilizing
+PTBP3,CACNA1B,0.06726329664521959,destabilizing
+PTBP3,FRY,0.09300891709764741,destabilizing
+PTBP3,MACROD2,0.07104083066893253,destabilizing
+PTBP3,CDK12,0.10980900729302102,destabilizing
+PTBP3,MPHOSPH8,0.06371553297637565,destabilizing
+PTBP3,CHST12,0.12381438589030636,destabilizing
+PTBP3,PSME4,0.07284117975569464,destabilizing
+PTBP3,NOVA1,0.09458039761394925,destabilizing
+PTBP3,ALK,0.10352141821942519,destabilizing
+PTBP3,XKR6,0.07497973179217499,destabilizing
+PTBP3,DMD,0.09564386311612513,destabilizing
+PTBP3,PRKN,0.11212736537997463,destabilizing
+PTBP3,RASA2,0.07347561581052331,destabilizing
+PTBP3,ARL3,0.05796046244916986,destabilizing
+PTBP3,SLIT2,0.11117958701992856,destabilizing
+PTBP3,UNC5C,0.07273610784763851,destabilizing
+PTBP3,NEGR1,0.0778240874119686,destabilizing
+PTBP3,TOMM22,0.08163313658455838,destabilizing
+PTBP3,EYS,0.06114447529758208,destabilizing
+PTBP3,MLLT3,0.12682581252359051,destabilizing
+PTBP3,PTPRD,0.07241856620823377,destabilizing
+PTBP3,LARP1B,0.07790322632284535,destabilizing
+PCBP2,TRERF1,0.33825889634751194,destabilizing
+PCBP2,SORCS1,0.23276110233152372,destabilizing
+PCBP2,NCOA1,0.10877103278243079,destabilizing
+PCBP2,COPA,0.15089392532189574,destabilizing
+PCBP2,FCHSD2,0.16572067349032654,destabilizing
+PCBP2,PDE3A,0.3715492113314007,destabilizing
+PCBP2,UNC79,0.32942180458995024,destabilizing
+PCBP2,DOC2B,0.26794038882135984,destabilizing
+PCBP2,TMTC2,0.30450515118802135,destabilizing
+PCBP2,KALRN,0.2089963221442367,destabilizing
+PCBP2,CHD1,0.18914119083949382,destabilizing
+PCBP2,PAK3,0.09061083855468116,destabilizing
+PCBP2,UBE2E2,0.1696268802506454,destabilizing
+PCBP2,PPARD,0.15910249879570562,destabilizing
+PCBP2,TOX,0.1447383191638024,destabilizing
+PCBP2,BRAF,0.12010978838677225,destabilizing
+PCBP2,RYR2,0.28372506981144735,destabilizing
+PCBP2,ZNF609,0.05547721895899157,destabilizing
+PCBP2,MTMR7,0.32053475633286,destabilizing
+PCBP2,EIF4E,0.24256254798644244,destabilizing
+PCBP2,SOX11,0.10869456245172433,destabilizing
+PCBP2,EPB41L4B,0.22226767129175617,destabilizing
+PCBP2,CACNA1B,0.1939285156939767,destabilizing
+PCBP2,TBC1D5,0.1061092805786585,destabilizing
+PCBP2,LRRTM4,0.2295291910450458,destabilizing
+PCBP2,SIRPA,0.28742300180325114,destabilizing
+PCBP2,MAP4K3,0.07208346336938877,destabilizing
+PCBP2,PTEN,0.2183855885569604,destabilizing
+PCBP2,SPPL3,0.0693920337469748,destabilizing
+PCBP2,FRY,0.342345587393318,destabilizing
+PCBP2,RUNX1T1,0.0762814049877335,destabilizing
+PCBP2,MACROD2,0.2995573326192834,destabilizing
+PCBP2,FOXN3,0.1265256515673318,destabilizing
+PCBP2,SHANK2,0.3399546253940779,destabilizing
+PCBP2,CDK12,0.3955170309653351,destabilizing
+PCBP2,BMPR1B,0.05952513721099178,destabilizing
+PCBP2,RFX7,0.3108579139419819,destabilizing
+PCBP2,UBR5,0.17648078306290613,destabilizing
+PCBP2,JARID2,0.18473569668430148,destabilizing
+PCBP2,MPHOSPH8,0.23757323712474376,destabilizing
+PCBP2,DIP2C,0.21619720834193765,destabilizing
+PCBP2,ZNF423,0.11141077279263645,destabilizing
+PCBP2,UBR3,0.18437509354604517,destabilizing
+PCBP2,MGAT5,0.12901489266267252,destabilizing
+PCBP2,DLG2,0.23860490225862752,destabilizing
+PCBP2,CHST12,0.4460658415362501,destabilizing
+PCBP2,EML5,0.3596897728597079,destabilizing
+PCBP2,CENPP,0.2871567607638709,destabilizing
+PCBP2,PSME4,0.2980450935086771,destabilizing
+PCBP2,TMEM106B,0.32349870095513567,destabilizing
+PCBP2,RABGAP1L,0.05840402352942216,destabilizing
+PCBP2,EPHA5,0.255707511475132,destabilizing
+PCBP2,KCNB2,0.27232479692445843,destabilizing
+PCBP2,ZNF83,0.17776022851188153,destabilizing
+PCBP2,SOX6,0.18854049402609413,destabilizing
+PCBP2,ZNF521,0.253558294874855,destabilizing
+PCBP2,PLEKHA5,0.19554357280850934,destabilizing
+PCBP2,DTL,0.1021774325986292,destabilizing
+PCBP2,NOVA1,0.3060279043259974,destabilizing
+PCBP2,CCNY,0.28991408578873734,destabilizing
+PCBP2,ARIH1,0.23847222132197085,destabilizing
+PCBP2,FAM171B,0.0945925885861019,destabilizing
+PCBP2,EPB41L5,0.21629367273791325,destabilizing
+PCBP2,GPR158,0.3289213232594131,destabilizing
+PCBP2,NCOA2,0.24503250870675608,destabilizing
+PCBP2,PUM2,0.05349316193003392,destabilizing
+PCBP2,ALK,0.36026221467798936,destabilizing
+PCBP2,ACACA,0.14864981973705574,destabilizing
+PCBP2,ARHGAP26,0.13291026724582544,destabilizing
+PCBP2,CTNND2,0.1439092747518228,destabilizing
+PCBP2,IFT172,0.3075593902225913,destabilizing
+PCBP2,CCNT1,0.19530589544423138,destabilizing
+PCBP2,DTWD2,0.3680014923554945,destabilizing
+PCBP2,SIK3,0.24153106012394238,destabilizing
+PCBP2,CPEB3,0.33064671017591574,destabilizing
+PCBP2,CADM2,0.14108837354434714,destabilizing
+PCBP2,XKR6,0.324515893731633,destabilizing
+PCBP2,RMND5A,0.10607169083444236,destabilizing
+PCBP2,CADPS,0.18197517036062025,destabilizing
+PCBP2,FGF13,0.13586049715571197,destabilizing
+PCBP2,TCF20,0.34104544231205663,destabilizing
+PCBP2,CDKAL1,0.16659984058245816,destabilizing
+PCBP2,DGKI,0.24403994413093513,destabilizing
+PCBP2,EXOC6B,0.3596635728420781,destabilizing
+PCBP2,MAGI3,0.2835333222679454,destabilizing
+PCBP2,SBF2,0.1783110807881418,destabilizing
+PCBP2,INPP4B,0.27545572175499344,destabilizing
+PCBP2,ERC1,0.13928004639710967,destabilizing
+PCBP2,PTPRS,0.3221823991528656,destabilizing
+PCBP2,CBFA2T2,0.16700673357686127,destabilizing
+PCBP2,SPDYE3,0.23797122977342924,destabilizing
+PCBP2,TMEM178B,0.15481811108792798,destabilizing
+PCBP2,KMT2C,0.07105810220722461,destabilizing
+PCBP2,CACNA2D1,0.10594636253631497,destabilizing
+PCBP2,DMD,0.39509474046748805,destabilizing
+PCBP2,EIF4G3,0.12801514652493184,destabilizing
+PCBP2,MCU,0.31048602959419164,destabilizing
+PCBP2,SSH2,0.24653023113179043,destabilizing
+PCBP2,TCF12,0.08508091126482668,destabilizing
+PCBP2,DOCK3,0.31590431163470184,destabilizing
+PCBP2,HS6ST3,0.29370623822835495,destabilizing
+PCBP2,LPP,0.38604320448181073,destabilizing
+PCBP2,STAG1,0.20936727951037062,destabilizing
+PCBP2,CAPZA2,0.27678175797600496,destabilizing
+PCBP2,ADGRL3,0.1637389028835719,destabilizing
+PCBP2,PHACTR1,0.15579449201683884,destabilizing
+PCBP2,UBE2R2,0.26988904078784454,destabilizing
+PCBP2,GTF2IRD1,0.2325905340843148,destabilizing
+PCBP2,CCBE1,0.17150899790280755,destabilizing
+PCBP2,FTX,0.09061167804881647,destabilizing
+PCBP2,VAPA,0.09701720844787419,destabilizing
+PCBP2,JMJD1C,0.09142460294514765,destabilizing
+PCBP2,TTC28,0.19092001604686043,destabilizing
+PCBP2,SBNO1,0.17508414107813136,destabilizing
+PCBP2,RIMS2,0.18213603523471214,destabilizing
+PCBP2,IGF1R,0.12375437295411774,destabilizing
+PCBP2,TRIO,0.14154370654317774,destabilizing
+PCBP2,KCND2,0.0883717475334227,destabilizing
+PCBP2,BTBD9,0.2829702617146906,destabilizing
+PCBP2,CNGB1,0.31833704734575186,destabilizing
+PCBP2,FMN2,0.2465618872159926,destabilizing
+PCBP2,ENSG00000228222,0.4286468612917422,destabilizing
+PCBP2,ATXN1,0.1314670608016333,destabilizing
+PCBP2,SYN3,0.08251469832669127,destabilizing
+PCBP2,PRKN,0.3778434658816594,destabilizing
+PCBP2,RASA2,0.2810129841832388,destabilizing
+PCBP2,PPP1R12B,0.24960912516813713,destabilizing
+PCBP2,FRMD4A,0.22813304802742307,destabilizing
+PCBP2,CAMK1D,0.14414787581876679,destabilizing
+PCBP2,PARD3,0.10244080276829617,destabilizing
+PCBP2,SEMA6D,0.2668992043346254,destabilizing
+PCBP2,WIPF2,0.276985333064108,destabilizing
+PCBP2,WWOX,0.06543800496156514,destabilizing
+PCBP2,DLEU1,0.41564690431155327,destabilizing
+PCBP2,TSHZ2,0.14059510112630805,destabilizing
+PCBP2,MED13L,0.1715124272098401,destabilizing
+PCBP2,AFF3,0.08701724330444938,destabilizing
+PCBP2,KAZN,0.2506510892215689,destabilizing
+PCBP2,KANSL1,0.1931579967543803,destabilizing
+PCBP2,FRMD5,0.23293967933088602,destabilizing
+PCBP2,LINC00174,0.26500169084833636,destabilizing
+PCBP2,PPM1E,0.2258541988039736,destabilizing
+PCBP2,ARL3,0.16066314455536965,destabilizing
+PCBP2,MBD5,0.23615061297263232,destabilizing
+PCBP2,ELAVL3,0.23032295533366293,destabilizing
+PCBP2,SLIT2,0.3819928144548193,destabilizing
+PCBP2,SLC8A1,0.12703849373737344,destabilizing
+PCBP2,CLASP1,0.22800105488567818,destabilizing
+PCBP2,DOCK4,0.10321445324137164,destabilizing
+PCBP2,UNC5C,0.28273293006098343,destabilizing
+PCBP2,CACNA2D3,-0.0863047932839298,stabilizing
+PCBP2,RC3H1,0.18216477400764133,destabilizing
+PCBP2,NEGR1,0.25230065476179236,destabilizing
+PCBP2,ENOX1,0.3823151978421774,destabilizing
+PCBP2,SCUBE1,0.13778701303355392,destabilizing
+PCBP2,GPHN,0.22549044370520946,destabilizing
+PCBP2,NAV3,0.29561031889878087,destabilizing
+PCBP2,EBF1,0.13269105642360576,destabilizing
+PCBP2,TOMM22,0.31526785545173763,destabilizing
+PCBP2,MBNL2,0.14260964325626474,destabilizing
+PCBP2,ANKFN1,0.11577067676229175,destabilizing
+PCBP2,MAGI2,0.13899846337688437,destabilizing
+PCBP2,LSAMP,0.1616415170670331,destabilizing
+PCBP2,AKAP6,0.28768284497193186,destabilizing
+PCBP2,TMED2,0.20950964660101928,destabilizing
+PCBP2,ZBTB20,0.30482169153102556,destabilizing
+PCBP2,GRIK2,0.22912278644846093,destabilizing
+PCBP2,MAML3,0.056418944562171926,destabilizing
+PCBP2,SOX5,0.21688451261484487,destabilizing
+PCBP2,LRRC37A3,0.33706483319037206,destabilizing
+PCBP2,TMEM132C,0.08549761503940131,destabilizing
+PCBP2,EYS,0.21245666618484274,destabilizing
+PCBP2,ARID1B,0.203125243002592,destabilizing
+PCBP2,PRKCE,0.1803539921646839,destabilizing
+PCBP2,RBFOX1,-0.08757868613696428,stabilizing
+PCBP2,SDK1,0.15398028747810844,destabilizing
+PCBP2,NRG1,0.1415140699433013,destabilizing
+PCBP2,RORA,0.05136710096327728,destabilizing
+PCBP2,MLLT3,0.3710989544290582,destabilizing
+PCBP2,AUTS2,0.06685464842317318,destabilizing
+PCBP2,FMN1,0.1512130204104057,destabilizing
+PCBP2,ADGRB3,0.16295693010750756,destabilizing
+PCBP2,ROBO1,0.2742272404035787,destabilizing
+PCBP2,SYPL1,0.172595256814316,destabilizing
+PCBP2,PTPRD,0.23603602807548843,destabilizing
+PCBP2,FAM155A,0.3371323726476168,destabilizing
+PCBP2,LARP1B,0.3295037584400265,destabilizing
+PCBP3,TRERF1,0.14802725512378984,destabilizing
+PCBP3,SORCS1,0.11273705104697425,destabilizing
+PCBP3,NCOA1,0.05823846447990958,destabilizing
+PCBP3,COPA,0.07910644711918988,destabilizing
+PCBP3,PDE3A,0.15034806156889838,destabilizing
+PCBP3,UNC79,0.1671605842375599,destabilizing
+PCBP3,DOC2B,0.1264803226423353,destabilizing
+PCBP3,TMTC2,0.15935099544379927,destabilizing
+PCBP3,KALRN,0.10702109576024951,destabilizing
+PCBP3,CHD1,0.08463426170365394,destabilizing
+PCBP3,PAK3,0.05386047745992369,destabilizing
+PCBP3,UBE2E2,0.08368271232943761,destabilizing
+PCBP3,PPARD,0.08021483654348596,destabilizing
+PCBP3,BRAF,0.06469923202155177,destabilizing
+PCBP3,RYR2,0.12960364964020518,destabilizing
+PCBP3,MTMR7,0.170740055146864,destabilizing
+PCBP3,EIF4E,0.1182795714994319,destabilizing
+PCBP3,SOX11,0.053699170852133105,destabilizing
+PCBP3,EPB41L4B,0.08769528812870656,destabilizing
+PCBP3,CACNA1B,0.09489122305814633,destabilizing
+PCBP3,LRRTM4,0.09646138311872737,destabilizing
+PCBP3,SIRPA,0.12464655813426168,destabilizing
+PCBP3,PTEN,0.10523200137096207,destabilizing
+PCBP3,FRY,0.1702382742213565,destabilizing
+PCBP3,MACROD2,0.124659281074188,destabilizing
+PCBP3,SHANK2,0.1923055937162985,destabilizing
+PCBP3,CDK12,0.20081755150094865,destabilizing
+PCBP3,RFX7,0.12083133554245293,destabilizing
+PCBP3,UBR5,0.07959294075186234,destabilizing
+PCBP3,JARID2,0.08695647839500352,destabilizing
+PCBP3,MPHOSPH8,0.12738482433472859,destabilizing
+PCBP3,DIP2C,0.10058009120094397,destabilizing
+PCBP3,ZNF423,0.06039228850802143,destabilizing
+PCBP3,UBR3,0.10371881024613586,destabilizing
+PCBP3,MGAT5,0.07498536354166176,destabilizing
+PCBP3,DLG2,0.09868875281577556,destabilizing
+PCBP3,CHST12,0.24719295592738136,destabilizing
+PCBP3,EML5,0.16418050373992002,destabilizing
+PCBP3,CENPP,0.13872801040974675,destabilizing
+PCBP3,PSME4,0.11923497326089888,destabilizing
+PCBP3,TMEM106B,0.16219469819355326,destabilizing
+PCBP3,EPHA5,0.10402058252762678,destabilizing
+PCBP3,KCNB2,0.12054719115990947,destabilizing
+PCBP3,ZNF83,0.0774920378969208,destabilizing
+PCBP3,SOX6,0.0817855314210459,destabilizing
+PCBP3,ZNF521,0.13318285876887465,destabilizing
+PCBP3,PLEKHA5,0.08205940881259044,destabilizing
+PCBP3,NOVA1,0.15934026944485857,destabilizing
+PCBP3,CCNY,0.12488504235844357,destabilizing
+PCBP3,ARIH1,0.11081274853198281,destabilizing
+PCBP3,FAM171B,0.06510255448241054,destabilizing
+PCBP3,EPB41L5,0.10626650107823746,destabilizing
+PCBP3,GPR158,0.1558581450487917,destabilizing
+PCBP3,NCOA2,0.11639838775796307,destabilizing
+PCBP3,ALK,0.1159240971237741,destabilizing
+PCBP3,ACACA,0.07883460772177266,destabilizing
+PCBP3,ARHGAP26,0.06080365381828058,destabilizing
+PCBP3,CTNND2,0.06256336951861088,destabilizing
+PCBP3,IFT172,0.11871365423363518,destabilizing
+PCBP3,CCNT1,0.11371449439884511,destabilizing
+PCBP3,DTWD2,0.14363328044582402,destabilizing
+PCBP3,SIK3,0.14136088147361642,destabilizing
+PCBP3,CPEB3,0.13982563992472685,destabilizing
+PCBP3,CADM2,0.06778254557890706,destabilizing
+PCBP3,XKR6,0.1543143926250008,destabilizing
+PCBP3,CADPS,0.08161720010432542,destabilizing
+PCBP3,FGF13,0.07742457505868107,destabilizing
+PCBP3,TCF20,0.1559023063219578,destabilizing
+PCBP3,DGKI,0.10883708369480387,destabilizing
+PCBP3,EXOC6B,0.17121201402324224,destabilizing
+PCBP3,MAGI3,0.14050555982337523,destabilizing
+PCBP3,SBF2,0.08935666150969622,destabilizing
+PCBP3,INPP4B,0.13261251225236947,destabilizing
+PCBP3,ERC1,0.06617074053472487,destabilizing
+PCBP3,PTPRS,0.16020635138767791,destabilizing
+PCBP3,CBFA2T2,0.08383543527099609,destabilizing
+PCBP3,SPDYE3,0.11528469011332092,destabilizing
+PCBP3,TMEM178B,0.06703918375688993,destabilizing
+PCBP3,KMT2C,0.054656272293722816,destabilizing
+PCBP3,DMD,0.192454295713706,destabilizing
+PCBP3,EIF4G3,0.0794589218899622,destabilizing
+PCBP3,MCU,0.11697030994520582,destabilizing
+PCBP3,SSH2,0.11679612496918888,destabilizing
+PCBP3,DOCK3,0.1539004688480983,destabilizing
+PCBP3,HS6ST3,0.10892956735845669,destabilizing
+PCBP3,LPP,0.19072070268393956,destabilizing
+PCBP3,STAG1,0.11751870384310056,destabilizing
+PCBP3,CAPZA2,0.1352310317726582,destabilizing
+PCBP3,ADGRL3,0.08022591490879305,destabilizing
+PCBP3,PHACTR1,0.06324004723427856,destabilizing
+PCBP3,UBE2R2,0.14294171279498732,destabilizing
+PCBP3,GTF2IRD1,0.10503862619079579,destabilizing
+PCBP3,CCBE1,0.07965465727512383,destabilizing
+PCBP3,TTC28,0.0870075627790039,destabilizing
+PCBP3,SBNO1,0.07798953061485868,destabilizing
+PCBP3,RIMS2,0.10031386476525003,destabilizing
+PCBP3,IGF1R,0.08575160893462697,destabilizing
+PCBP3,TRIO,0.062493520595667165,destabilizing
+PCBP3,BTBD9,0.16046316420102563,destabilizing
+PCBP3,CNGB1,0.1557015815360836,destabilizing
+PCBP3,FMN2,0.13487080955336608,destabilizing
+PCBP3,ENSG00000228222,0.20241628681148935,destabilizing
+PCBP3,SYN3,0.055783956033032045,destabilizing
+PCBP3,PRKN,0.16199276574614968,destabilizing
+PCBP3,RASA2,0.1542052458415194,destabilizing
+PCBP3,PPP1R12B,0.09843660541889324,destabilizing
+PCBP3,FRMD4A,0.13510428905080554,destabilizing
+PCBP3,CAMK1D,0.0634739296116696,destabilizing
+PCBP3,PARD3,0.05221477999877454,destabilizing
+PCBP3,SEMA6D,0.12143766860812841,destabilizing
+PCBP3,WIPF2,0.13438732632700365,destabilizing
+PCBP3,DLEU1,0.1652600485020885,destabilizing
+PCBP3,TSHZ2,0.09329610502917896,destabilizing
+PCBP3,MED13L,0.09297541441675711,destabilizing
+PCBP3,KAZN,0.12088087792637328,destabilizing
+PCBP3,KANSL1,0.07281264122102507,destabilizing
+PCBP3,FRMD5,0.13731364459306958,destabilizing
+PCBP3,LINC00174,0.1290724257760992,destabilizing
+PCBP3,PPM1E,0.12222546247882812,destabilizing
+PCBP3,ARL3,0.10248221430244539,destabilizing
+PCBP3,MBD5,0.10112442198352707,destabilizing
+PCBP3,ELAVL3,0.11055331487533773,destabilizing
+PCBP3,SLIT2,0.15088459036505916,destabilizing
+PCBP3,CLASP1,0.1160872400885421,destabilizing
+PCBP3,UNC5C,0.13304851428470688,destabilizing
+PCBP3,CACNA2D3,-0.06239065180524022,stabilizing
+PCBP3,RC3H1,0.11871771767527266,destabilizing
+PCBP3,NEGR1,0.12535838721250372,destabilizing
+PCBP3,ENOX1,0.19832072198238376,destabilizing
+PCBP3,SCUBE1,0.08627293555264678,destabilizing
+PCBP3,GPHN,0.11129951785601304,destabilizing
+PCBP3,NAV3,0.13302046288640382,destabilizing
+PCBP3,EBF1,0.06012702248687896,destabilizing
+PCBP3,TOMM22,0.16973007943729282,destabilizing
+PCBP3,MBNL2,0.08486819406878726,destabilizing
+PCBP3,MAGI2,0.06216505666359853,destabilizing
+PCBP3,LSAMP,0.10368064128072535,destabilizing
+PCBP3,AKAP6,0.1394939488819983,destabilizing
+PCBP3,TMED2,0.11899340532977687,destabilizing
+PCBP3,ZBTB20,0.11851184019200643,destabilizing
+PCBP3,GRIK2,0.1382595403563681,destabilizing
+PCBP3,SOX5,0.08554630362100941,destabilizing
+PCBP3,LRRC37A3,0.17882705136080243,destabilizing
+PCBP3,EYS,0.10019126439859243,destabilizing
+PCBP3,ARID1B,0.0984021163006891,destabilizing
+PCBP3,PRKCE,0.08721903849605513,destabilizing
+PCBP3,RBFOX1,-0.05566129819033196,stabilizing
+PCBP3,NRG1,0.08282312545597686,destabilizing
+PCBP3,MLLT3,0.17158185590437433,destabilizing
+PCBP3,FMN1,0.09276099985548783,destabilizing
+PCBP3,ADGRB3,0.08803053120506549,destabilizing
+PCBP3,ROBO1,0.12212007155949837,destabilizing
+PCBP3,SYPL1,0.08081830396293069,destabilizing
+PCBP3,PTPRD,0.10622638591947199,destabilizing
+PCBP3,FAM155A,0.1331626129574745,destabilizing
+PCBP3,LARP1B,0.14146806043405152,destabilizing
+IGF2BP3,NOVA1,0.0955774459620947,destabilizing
+IGF2BP3,DMD,0.0917046607153112,destabilizing
+IGF2BP3,ENSG00000228222,0.12372020295466002,destabilizing
+IGF2BP3,PTPRD,0.06827720924810778,destabilizing
+FMR1,CENPP,0.11823876725355183,destabilizing
+FXR1,TRERF1,0.15072708043767505,destabilizing
+FXR1,SORCS1,0.10369807977992804,destabilizing
+FXR1,PDE3A,0.18224086965852695,destabilizing
+FXR1,UNC79,0.17005180126369132,destabilizing
+FXR1,DOC2B,0.12260862924511567,destabilizing
+FXR1,TMTC2,0.12935668698951744,destabilizing
+FXR1,KALRN,0.11154635318726933,destabilizing
+FXR1,CHD1,0.09425402575450753,destabilizing
+FXR1,TOX,0.07505475907759693,destabilizing
+FXR1,RYR2,0.13632983077284636,destabilizing
+FXR1,MTMR7,0.1663750829922606,destabilizing
+FXR1,EIF4E,0.1324709226729999,destabilizing
+FXR1,SOX11,0.054710758953532314,destabilizing
+FXR1,EPB41L4B,0.09164271316235031,destabilizing
+FXR1,CACNA1B,0.08760986860833286,destabilizing
+FXR1,LRRTM4,0.11700868080506205,destabilizing
+FXR1,SIRPA,0.11682498254071219,destabilizing
+FXR1,PTEN,0.12185265004768354,destabilizing
+FXR1,FRY,0.15805707785979425,destabilizing
+FXR1,MACROD2,0.16015329689571547,destabilizing
+FXR1,SHANK2,0.19185285152591333,destabilizing
+FXR1,CDK12,0.21781713039264916,destabilizing
+FXR1,RFX7,0.18962338655765631,destabilizing
+FXR1,UBR5,0.06265753159950907,destabilizing
+FXR1,JARID2,0.07019916718943411,destabilizing
+FXR1,MPHOSPH8,0.10406469844361035,destabilizing
+FXR1,DIP2C,0.11096663875017553,destabilizing
+FXR1,UBR3,0.09039271440284265,destabilizing
+FXR1,MGAT5,0.05976021252651693,destabilizing
+FXR1,DLG2,0.10834087890381693,destabilizing
+FXR1,CHST12,0.2221358943978261,destabilizing
+FXR1,EML5,0.14057731964844739,destabilizing
+FXR1,CENPP,0.14290007140920505,destabilizing
+FXR1,PSME4,0.12220470547913342,destabilizing
+FXR1,TMEM106B,0.1395325689912804,destabilizing
+FXR1,EPHA5,0.11962580948156312,destabilizing
+FXR1,KCNB2,0.15141287564081116,destabilizing
+FXR1,ZNF83,0.09981935288109291,destabilizing
+FXR1,SOX6,0.07726268065877455,destabilizing
+FXR1,ZNF521,0.13079275812691601,destabilizing
+FXR1,PLEKHA5,0.08900239792156252,destabilizing
+FXR1,NOVA1,0.18359351221562584,destabilizing
+FXR1,CCNY,0.14925708748717126,destabilizing
+FXR1,ARIH1,0.09679450617085722,destabilizing
+FXR1,EPB41L5,0.10133874556053528,destabilizing
+FXR1,GPR158,0.156291241600866,destabilizing
+FXR1,NCOA2,0.10237505148924927,destabilizing
+FXR1,ALK,0.14224704667502228,destabilizing
+FXR1,ACACA,0.0637400364769458,destabilizing
+FXR1,IFT172,0.1685728101960105,destabilizing
+FXR1,CCNT1,0.06806017015037238,destabilizing
+FXR1,DTWD2,0.1478400895520146,destabilizing
+FXR1,SIK3,0.10830525310602433,destabilizing
+FXR1,CPEB3,0.15627500524679983,destabilizing
+FXR1,CADM2,0.06229572910667075,destabilizing
+FXR1,XKR6,0.1738285953743153,destabilizing
+FXR1,CADPS,0.10083818905447758,destabilizing
+FXR1,TCF20,0.13032819887182018,destabilizing
+FXR1,DGKI,0.10449588521930248,destabilizing
+FXR1,EXOC6B,0.15899344450459668,destabilizing
+FXR1,MAGI3,0.14523773793714367,destabilizing
+FXR1,SBF2,0.07362832451659722,destabilizing
+FXR1,INPP4B,0.12040731885307293,destabilizing
+FXR1,PTPRS,0.21085681004347917,destabilizing
+FXR1,CBFA2T2,0.061093981242636916,destabilizing
+FXR1,SPDYE3,0.10602848222817995,destabilizing
+FXR1,TMEM178B,0.06822789372346354,destabilizing
+FXR1,DMD,0.21850800223352734,destabilizing
+FXR1,MCU,0.1275727948751203,destabilizing
+FXR1,SSH2,0.10475400922503972,destabilizing
+FXR1,DOCK3,0.15531894917073585,destabilizing
+FXR1,HS6ST3,0.14880321743827296,destabilizing
+FXR1,LPP,0.1635506154854482,destabilizing
+FXR1,STAG1,0.08163431392651284,destabilizing
+FXR1,CAPZA2,0.1284131073554688,destabilizing
+FXR1,ADGRL3,0.0834001008513854,destabilizing
+FXR1,UBE2R2,0.1250809679459418,destabilizing
+FXR1,GTF2IRD1,0.11580896262388926,destabilizing
+FXR1,CCBE1,0.060568101021226124,destabilizing
+FXR1,TTC28,0.08724661890280405,destabilizing
+FXR1,SBNO1,0.0754632415826063,destabilizing
+FXR1,RIMS2,0.07443373988919685,destabilizing
+FXR1,TRIO,0.061923138201392613,destabilizing
+FXR1,KCND2,0.05847285772383956,destabilizing
+FXR1,BTBD9,0.11455781738909535,destabilizing
+FXR1,CNGB1,0.1728562728387773,destabilizing
+FXR1,FMN2,0.0933390731994595,destabilizing
+FXR1,ENSG00000228222,0.206882590130842,destabilizing
+FXR1,PRKN,0.15586376504918295,destabilizing
+FXR1,RASA2,0.13704362025572148,destabilizing
+FXR1,PPP1R12B,0.09557548933296843,destabilizing
+FXR1,FRMD4A,0.09065555656420307,destabilizing
+FXR1,SEMA6D,0.1138815790553056,destabilizing
+FXR1,WIPF2,0.12805357238008053,destabilizing
+FXR1,DLEU1,0.16672296669582493,destabilizing
+FXR1,TSHZ2,0.07904942132037929,destabilizing
+FXR1,MED13L,0.07647486487835442,destabilizing
+FXR1,KAZN,0.12976994267917952,destabilizing
+FXR1,KANSL1,0.07503157669270853,destabilizing
+FXR1,FRMD5,0.13844089660772035,destabilizing
+FXR1,LINC00174,0.12506308630275598,destabilizing
+FXR1,PPM1E,0.11544910092113742,destabilizing
+FXR1,ARL3,0.08676919395671072,destabilizing
+FXR1,MBD5,0.12288602056318547,destabilizing
+FXR1,ELAVL3,0.13324392793219433,destabilizing
+FXR1,SLIT2,0.19205763555186434,destabilizing
+FXR1,CLASP1,0.08929444143430694,destabilizing
+FXR1,UNC5C,0.13817519415216423,destabilizing
+FXR1,RC3H1,0.0697930693578269,destabilizing
+FXR1,NEGR1,0.15785650641413487,destabilizing
+FXR1,ENOX1,0.1679593663613213,destabilizing
+FXR1,SCUBE1,0.06487273352920367,destabilizing
+FXR1,GPHN,0.10923446572425509,destabilizing
+FXR1,NAV3,0.17682854231997866,destabilizing
+FXR1,EBF1,0.05762792152404155,destabilizing
+FXR1,TOMM22,0.15965260057350425,destabilizing
+FXR1,MAGI2,0.05857174119015547,destabilizing
+FXR1,LSAMP,0.07016846502816618,destabilizing
+FXR1,AKAP6,0.11163654841048624,destabilizing
+FXR1,TMED2,0.095572349382798,destabilizing
+FXR1,ZBTB20,0.14947694972262152,destabilizing
+FXR1,GRIK2,0.1198356313753184,destabilizing
+FXR1,SOX5,0.09238824084620312,destabilizing
+FXR1,LRRC37A3,0.15476811127194431,destabilizing
+FXR1,EYS,0.09137284624465336,destabilizing
+FXR1,ARID1B,0.09510280191939896,destabilizing
+FXR1,PRKCE,0.0833789581928687,destabilizing
+FXR1,RBFOX1,-0.06947166093153664,stabilizing
+FXR1,SDK1,0.06838335203830366,destabilizing
+FXR1,NRG1,0.06280638346855957,destabilizing
+FXR1,MLLT3,0.2115717641056164,destabilizing
+FXR1,ADGRB3,0.06646688151941764,destabilizing
+FXR1,ROBO1,0.1390772437189607,destabilizing
+FXR1,SYPL1,0.062147371017722504,destabilizing
+FXR1,PTPRD,0.11911197985929232,destabilizing
+FXR1,FAM155A,0.16259403730047106,destabilizing
+FXR1,LARP1B,0.14111710102248068,destabilizing
+FXR2,UNC79,0.10383766123958507,destabilizing
+FXR2,DOC2B,0.07463788336989981,destabilizing
+FXR2,KALRN,0.06364742529987315,destabilizing
+FXR2,MTMR7,0.08564255358175467,destabilizing
+FXR2,EIF4E,0.10430773092309391,destabilizing
+FXR2,FRY,0.09184839451828714,destabilizing
+FXR2,MACROD2,0.07604484503104578,destabilizing
+FXR2,SHANK2,0.11510703859923745,destabilizing
+FXR2,CDK12,0.12612522136618542,destabilizing
+FXR2,MPHOSPH8,0.06777295773153033,destabilizing
+FXR2,DLG2,0.08175479094235776,destabilizing
+FXR2,CHST12,0.14782297586135845,destabilizing
+FXR2,EML5,0.07795898171173365,destabilizing
+FXR2,CENPP,0.12213641252518308,destabilizing
+FXR2,TMEM106B,0.10378363330370137,destabilizing
+FXR2,KCNB2,0.11580690897166865,destabilizing
+FXR2,SOX6,0.060712498580887356,destabilizing
+FXR2,NOVA1,0.11852391736690508,destabilizing
+FXR2,CCNY,0.1059927802264663,destabilizing
+FXR2,ARIH1,0.06463431610490583,destabilizing
+FXR2,GPR158,0.11162484801803245,destabilizing
+FXR2,NCOA2,0.075830867408619,destabilizing
+FXR2,IFT172,0.08547253202183466,destabilizing
+FXR2,DTWD2,0.14723411282503676,destabilizing
+FXR2,CPEB3,0.11551436938964993,destabilizing
+FXR2,XKR6,0.12288105906220041,destabilizing
+FXR2,CADPS,0.05617195627342133,destabilizing
+FXR2,DGKI,0.07645153959568263,destabilizing
+FXR2,MAGI3,0.08281128303561981,destabilizing
+FXR2,INPP4B,0.0861744522570078,destabilizing
+FXR2,DMD,0.13499157665070172,destabilizing
+FXR2,DOCK3,0.11051221670579817,destabilizing
+FXR2,CAPZA2,0.07329078600759328,destabilizing
+FXR2,CNGB1,0.08170632032362345,destabilizing
+FXR2,ENSG00000228222,0.1201992441544733,destabilizing
+FXR2,PRKN,0.10888994298665142,destabilizing
+FXR2,RASA2,0.08336824563815946,destabilizing
+FXR2,PPP1R12B,0.06666628082031797,destabilizing
+FXR2,FRMD4A,0.06315580226116155,destabilizing
+FXR2,SEMA6D,0.07901118758194729,destabilizing
+FXR2,WIPF2,0.08962713885323564,destabilizing
+FXR2,LINC00174,0.06326395567538319,destabilizing
+FXR2,MBD5,0.0730499613911698,destabilizing
+FXR2,ELAVL3,0.06379361965373734,destabilizing
+FXR2,SLIT2,0.09754246552002176,destabilizing
+FXR2,UNC5C,0.09262668435149904,destabilizing
+FXR2,NEGR1,0.0952897846626861,destabilizing
+FXR2,ENOX1,0.14993695579915242,destabilizing
+FXR2,NAV3,0.07823433436328084,destabilizing
+FXR2,TOMM22,0.10664926157119857,destabilizing
+FXR2,AKAP6,0.07399356391651767,destabilizing
+FXR2,ZBTB20,0.07257325237212177,destabilizing
+FXR2,LRRC37A3,0.09572566779706392,destabilizing
+FXR2,EYS,0.05664563250169388,destabilizing
+FXR2,MLLT3,0.11164224068592893,destabilizing
+FXR2,LARP1B,0.062280127625899954,destabilizing
+MBNL2,UNC79,0.09388125485470455,destabilizing
+MBNL2,TMTC2,0.07656081119428336,destabilizing
+MBNL2,MACROD2,0.07239506629479234,destabilizing
+MBNL2,CDK12,0.1122404385222683,destabilizing
+MBNL2,EML5,0.08167451979208379,destabilizing
+MBNL2,TMEM106B,0.09596629071000126,destabilizing
+MBNL2,XKR6,0.07711724907788786,destabilizing
+MBNL2,EXOC6B,0.08804874466095697,destabilizing
+MBNL2,PTPRS,0.13967279858806161,destabilizing
+MBNL2,LPP,0.1107908347867332,destabilizing
+MBNL2,ELAVL3,0.061435052314376154,destabilizing
+MBNL2,MBNL2,-0.33793877167390185,stabilizing
+MBNL2,LARP1B,0.06947679617138144,destabilizing
+CELF1,DMD,0.07987156865061115,destabilizing
+CELF1,MLLT3,0.08784879195952248,destabilizing
+CELF2,TRERF1,0.07896698932455697,destabilizing
+CELF2,FRY,0.09008367782166721,destabilizing
+CELF2,CDK12,0.09709541675415485,destabilizing
+CELF2,MPHOSPH8,0.06626655932285312,destabilizing
+CELF2,CENPP,0.12130499666493208,destabilizing
+CELF2,NOVA1,0.0929192958542478,destabilizing
+CELF2,CCNT1,0.05733028939293565,destabilizing
+CELF2,MAGI3,0.06740726622852057,destabilizing
+CELF2,DMD,0.09082721404403789,destabilizing
+CELF2,DOCK3,0.10285946782032246,destabilizing
+CELF2,PTPRD,0.0635592341357154,destabilizing
+CELF4,TRERF1,0.12236148380498647,destabilizing
+CELF4,SORCS1,0.07722109314321123,destabilizing
+CELF4,PDE3A,0.12728379414884913,destabilizing
+CELF4,UNC79,0.12862863058740195,destabilizing
+CELF4,DOC2B,0.08629133537736836,destabilizing
+CELF4,TMTC2,0.11485434360392974,destabilizing
+CELF4,KALRN,0.10625579385293304,destabilizing
+CELF4,CHD1,0.055908552973819435,destabilizing
+CELF4,MTMR7,0.14240419401091053,destabilizing
+CELF4,EPB41L4B,0.10474261780141628,destabilizing
+CELF4,CACNA1B,0.07954454176422268,destabilizing
+CELF4,LRRTM4,0.08908620966834366,destabilizing
+CELF4,FRY,0.10493630534891522,destabilizing
+CELF4,MACROD2,0.11122604925059618,destabilizing
+CELF4,SHANK2,0.13613785872950565,destabilizing
+CELF4,CDK12,0.1462420236743995,destabilizing
+CELF4,RFX7,0.12910910694287414,destabilizing
+CELF4,JARID2,0.05696171992297806,destabilizing
+CELF4,MPHOSPH8,0.08714739337805906,destabilizing
+CELF4,DIP2C,0.0729629238406677,destabilizing
+CELF4,UBR3,0.07809002168771989,destabilizing
+CELF4,MGAT5,0.05268236700735613,destabilizing
+CELF4,DLG2,0.06174336665115663,destabilizing
+CELF4,CHST12,0.20032644000040864,destabilizing
+CELF4,EML5,0.13390093688013296,destabilizing
+CELF4,PSME4,0.10542072822529816,destabilizing
+CELF4,TMEM106B,0.09644695290389968,destabilizing
+CELF4,EPHA5,0.09819922137407126,destabilizing
+CELF4,KCNB2,0.09109430688677507,destabilizing
+CELF4,ZNF83,0.08386348111003318,destabilizing
+CELF4,SOX6,0.07934531149196847,destabilizing
+CELF4,ZNF521,0.12516529046026736,destabilizing
+CELF4,PLEKHA5,0.05713566825979742,destabilizing
+CELF4,NOVA1,0.1220373147414334,destabilizing
+CELF4,CCNY,0.09664228361723654,destabilizing
+CELF4,ARIH1,0.0791187402258273,destabilizing
+CELF4,EPB41L5,0.08658907361318208,destabilizing
+CELF4,GPR158,0.11690721239155928,destabilizing
+CELF4,NCOA2,0.07972295558729903,destabilizing
+CELF4,ACACA,0.05574011917795647,destabilizing
+CELF4,IFT172,0.10628537527787094,destabilizing
+CELF4,CCNT1,0.054936559113727204,destabilizing
+CELF4,CPEB3,0.10832877097683469,destabilizing
+CELF4,CADM2,0.07358393435666509,destabilizing
+CELF4,XKR6,0.11254707026679243,destabilizing
+CELF4,CADPS,0.06055365009720584,destabilizing
+CELF4,TCF20,0.10544394653489703,destabilizing
+CELF4,CDKAL1,0.09274161950339622,destabilizing
+CELF4,DGKI,0.08327365792539711,destabilizing
+CELF4,EXOC6B,0.11470104973837698,destabilizing
+CELF4,MAGI3,0.09557618181001806,destabilizing
+CELF4,INPP4B,0.12447068372902685,destabilizing
+CELF4,PTPRS,0.11938066157034871,destabilizing
+CELF4,SPDYE3,0.0700879014574669,destabilizing
+CELF4,DMD,0.14205154861167532,destabilizing
+CELF4,MCU,0.06630688751976956,destabilizing
+CELF4,SSH2,0.08194534867565627,destabilizing
+CELF4,DOCK3,0.10988708033304943,destabilizing
+CELF4,HS6ST3,0.14226187066033333,destabilizing
+CELF4,LPP,0.13628565505541665,destabilizing
+CELF4,STAG1,0.10731826226422261,destabilizing
+CELF4,CAPZA2,0.1195153377455562,destabilizing
+CELF4,ADGRL3,0.08463772831617784,destabilizing
+CELF4,UBE2R2,0.1116290760106137,destabilizing
+CELF4,GTF2IRD1,0.08619345195527381,destabilizing
+CELF4,CCBE1,0.05764714962708973,destabilizing
+CELF4,TTC28,0.09251703130580399,destabilizing
+CELF4,RIMS2,0.06604096545330877,destabilizing
+CELF4,IGF1R,0.059863038079943275,destabilizing
+CELF4,BTBD9,0.09557280539500038,destabilizing
+CELF4,CNGB1,0.16046052986359785,destabilizing
+CELF4,FMN2,0.08946315700323688,destabilizing
+CELF4,ENSG00000228222,0.18785503066169576,destabilizing
+CELF4,ATXN1,0.058152372042689096,destabilizing
+CELF4,PRKN,0.16757048658088847,destabilizing
+CELF4,RASA2,0.0988482989618312,destabilizing
+CELF4,PPP1R12B,0.06491605706511756,destabilizing
+CELF4,FRMD4A,0.0922287260925091,destabilizing
+CELF4,SEMA6D,0.09195483175199469,destabilizing
+CELF4,WIPF2,0.11436512833410845,destabilizing
+CELF4,DLEU1,0.10792842681703364,destabilizing
+CELF4,KAZN,0.0912165900989643,destabilizing
+CELF4,FRMD5,0.08825016345918123,destabilizing
+CELF4,LINC00174,0.0957690613885284,destabilizing
+CELF4,ARL3,0.06265708119941182,destabilizing
+CELF4,MBD5,0.0692245313996718,destabilizing
+CELF4,ELAVL3,0.09596159751947114,destabilizing
+CELF4,SLIT2,0.15141881189684578,destabilizing
+CELF4,CLASP1,0.07386114586050992,destabilizing
+CELF4,UNC5C,0.10946062256202377,destabilizing
+CELF4,CACNA2D3,-0.05623668498053921,stabilizing
+CELF4,RC3H1,0.06336831005531234,destabilizing
+CELF4,NEGR1,0.11730764199761139,destabilizing
+CELF4,ENOX1,0.14366438875340506,destabilizing
+CELF4,SCUBE1,0.07614579978392079,destabilizing
+CELF4,GPHN,0.0916979775780614,destabilizing
+CELF4,NAV3,0.11329636960826962,destabilizing
+CELF4,TOMM22,0.14284156297932873,destabilizing
+CELF4,LSAMP,0.05847915431759243,destabilizing
+CELF4,AKAP6,0.11466275151769792,destabilizing
+CELF4,TMED2,0.07779793330834461,destabilizing
+CELF4,ZBTB20,0.07819809349325939,destabilizing
+CELF4,GRIK2,0.1073201637168304,destabilizing
+CELF4,LRRC37A3,0.14797008449629917,destabilizing
+CELF4,EYS,0.08454401950568899,destabilizing
+CELF4,ARID1B,0.07313682338606782,destabilizing
+CELF4,RBFOX1,-0.06647754857604969,stabilizing
+CELF4,SDK1,0.07187613876237743,destabilizing
+CELF4,MLLT3,0.16663863702665016,destabilizing
+CELF4,ADGRB3,0.07336035797796,destabilizing
+CELF4,ROBO1,0.10213539529187407,destabilizing
+CELF4,SYPL1,0.05939916488960753,destabilizing
+CELF4,PTPRD,0.10041301417599187,destabilizing
+CELF4,FAM155A,0.11579864736504782,destabilizing
+CELF4,LARP1B,0.10848351062685692,destabilizing
+QKI,PUM2,-0.05703765625713527,stabilizing
+KHDRBS1,TRERF1,0.17397449909392249,destabilizing
+KHDRBS1,SORCS1,0.10027424965326717,destabilizing
+KHDRBS1,NCOA1,0.05919444911649349,destabilizing
+KHDRBS1,COPA,0.07376519760033752,destabilizing
+KHDRBS1,FCHSD2,0.08830993899630304,destabilizing
+KHDRBS1,PDE3A,0.18505531631781083,destabilizing
+KHDRBS1,UNC79,0.17987778319426886,destabilizing
+KHDRBS1,DOC2B,0.14535523935767397,destabilizing
+KHDRBS1,TMTC2,0.19573303452507007,destabilizing
+KHDRBS1,KALRN,0.13584963947778278,destabilizing
+KHDRBS1,CHD1,0.07241135291585962,destabilizing
+KHDRBS1,PAK3,0.057503556600839126,destabilizing
+KHDRBS1,UBE2E2,0.08043214475213464,destabilizing
+KHDRBS1,PPARD,0.09046945750684217,destabilizing
+KHDRBS1,TOX,0.0868128087544013,destabilizing
+KHDRBS1,BRAF,0.08822925705835381,destabilizing
+KHDRBS1,RYR2,0.19294655895795304,destabilizing
+KHDRBS1,MTMR7,0.19114916039411478,destabilizing
+KHDRBS1,EIF4E,0.19302890143629756,destabilizing
+KHDRBS1,EPB41L4B,0.0973558824152688,destabilizing
+KHDRBS1,CACNA1B,0.10406419950962303,destabilizing
+KHDRBS1,TBC1D5,0.05906031054324232,destabilizing
+KHDRBS1,LRRTM4,0.11939073255638136,destabilizing
+KHDRBS1,SIRPA,0.12888211428063207,destabilizing
+KHDRBS1,PTEN,0.12879750105957485,destabilizing
+KHDRBS1,FRY,0.19830762288245862,destabilizing
+KHDRBS1,RUNX1T1,0.0710035951852661,destabilizing
+KHDRBS1,MACROD2,0.17848257076669682,destabilizing
+KHDRBS1,SHANK2,0.2106962818177205,destabilizing
+KHDRBS1,CDK12,0.2460682654088887,destabilizing
+KHDRBS1,RFX7,0.19759975819560377,destabilizing
+KHDRBS1,UBR5,0.07261201828522364,destabilizing
+KHDRBS1,JARID2,0.07625309926628493,destabilizing
+KHDRBS1,MPHOSPH8,0.16733618534617536,destabilizing
+KHDRBS1,DIP2C,0.11337268185498263,destabilizing
+KHDRBS1,ZNF423,0.06255867080161134,destabilizing
+KHDRBS1,UBR3,0.11125026829402145,destabilizing
+KHDRBS1,MGAT5,0.06321261119198383,destabilizing
+KHDRBS1,DLG2,0.1376270302309887,destabilizing
+KHDRBS1,CHST12,0.25622345172674593,destabilizing
+KHDRBS1,EML5,0.20478693416451446,destabilizing
+KHDRBS1,CENPP,0.23714215632842905,destabilizing
+KHDRBS1,PSME4,0.1532032291297778,destabilizing
+KHDRBS1,TMEM106B,0.1786973252492116,destabilizing
+KHDRBS1,EPHA5,0.13802833615868876,destabilizing
+KHDRBS1,KCNB2,0.19571311588182305,destabilizing
+KHDRBS1,ZNF83,0.10651199203404195,destabilizing
+KHDRBS1,SOX6,0.12473569352272405,destabilizing
+KHDRBS1,ZNF521,0.15543498970608743,destabilizing
+KHDRBS1,PLEKHA5,0.09891243581138723,destabilizing
+KHDRBS1,NOVA1,0.19683560612499876,destabilizing
+KHDRBS1,CCNY,0.15563754404405386,destabilizing
+KHDRBS1,ARIH1,0.1288674677844355,destabilizing
+KHDRBS1,EPB41L5,0.1126259976775492,destabilizing
+KHDRBS1,GPR158,0.18659417469691703,destabilizing
+KHDRBS1,NCOA2,0.11635700034478458,destabilizing
+KHDRBS1,ALK,0.21163477031274033,destabilizing
+KHDRBS1,CTNND2,0.07236627819743277,destabilizing
+KHDRBS1,IFT172,0.17091989904153082,destabilizing
+KHDRBS1,CCNT1,0.10065664386090684,destabilizing
+KHDRBS1,DTWD2,0.3277369841429196,destabilizing
+KHDRBS1,SIK3,0.13601349052299133,destabilizing
+KHDRBS1,CPEB3,0.2072780330506742,destabilizing
+KHDRBS1,CADM2,0.0864036439919764,destabilizing
+KHDRBS1,XKR6,0.18696641613028428,destabilizing
+KHDRBS1,RMND5A,0.06490519996019468,destabilizing
+KHDRBS1,CADPS,0.08711821779801009,destabilizing
+KHDRBS1,FGF13,0.07977810850144096,destabilizing
+KHDRBS1,TCF20,0.15325354751702286,destabilizing
+KHDRBS1,CDKAL1,0.07558764875355435,destabilizing
+KHDRBS1,DGKI,0.14109980659791052,destabilizing
+KHDRBS1,EXOC6B,0.19160630716631447,destabilizing
+KHDRBS1,MAGI3,0.15457250167092892,destabilizing
+KHDRBS1,SBF2,0.07675681819494787,destabilizing
+KHDRBS1,INPP4B,0.11997600786035571,destabilizing
+KHDRBS1,ERC1,0.06269691804558124,destabilizing
+KHDRBS1,PTPRS,0.18733014397943193,destabilizing
+KHDRBS1,CBFA2T2,0.06032168988246189,destabilizing
+KHDRBS1,SPDYE3,0.12538009220882834,destabilizing
+KHDRBS1,TMEM178B,0.08441833356185066,destabilizing
+KHDRBS1,DMD,0.2425945065421184,destabilizing
+KHDRBS1,EIF4G3,0.06681873757682985,destabilizing
+KHDRBS1,MCU,0.16046390552782927,destabilizing
+KHDRBS1,SSH2,0.15254995582805808,destabilizing
+KHDRBS1,DOCK3,0.21431828985047607,destabilizing
+KHDRBS1,HS6ST3,0.19211657611896185,destabilizing
+KHDRBS1,LPP,0.17797221817874634,destabilizing
+KHDRBS1,STAG1,0.11749195809689429,destabilizing
+KHDRBS1,CAPZA2,0.16133206879613537,destabilizing
+KHDRBS1,ADGRL3,0.09003049346784257,destabilizing
+KHDRBS1,PHACTR1,0.0922818494125254,destabilizing
+KHDRBS1,UBE2R2,0.12581463735907744,destabilizing
+KHDRBS1,GTF2IRD1,0.10857067488133329,destabilizing
+KHDRBS1,CCBE1,0.07070918696826839,destabilizing
+KHDRBS1,FTX,0.07307805286284506,destabilizing
+KHDRBS1,VAPA,0.0654524970526244,destabilizing
+KHDRBS1,TTC28,0.10512861477352595,destabilizing
+KHDRBS1,SBNO1,0.08800333468656149,destabilizing
+KHDRBS1,RIMS2,0.11775892927537039,destabilizing
+KHDRBS1,KCND2,0.05836471531418555,destabilizing
+KHDRBS1,BTBD9,0.15182741526645027,destabilizing
+KHDRBS1,CNGB1,0.16070189465376386,destabilizing
+KHDRBS1,FMN2,0.11868199353753298,destabilizing
+KHDRBS1,ENSG00000228222,0.2331806089390625,destabilizing
+KHDRBS1,ATXN1,0.07673786505485161,destabilizing
+KHDRBS1,SYN3,0.05096010990954973,destabilizing
+KHDRBS1,PRKN,0.18265814599155947,destabilizing
+KHDRBS1,RASA2,0.1843627694857719,destabilizing
+KHDRBS1,PPP1R12B,0.11759398321409958,destabilizing
+KHDRBS1,FRMD4A,0.10545502326619642,destabilizing
+KHDRBS1,CAMK1D,0.0756336540543325,destabilizing
+KHDRBS1,PARD3,0.06222344819409367,destabilizing
+KHDRBS1,SEMA6D,0.14968895868765195,destabilizing
+KHDRBS1,WIPF2,0.17631786353268367,destabilizing
+KHDRBS1,DLEU1,0.2605740512324363,destabilizing
+KHDRBS1,TSHZ2,0.08367988195601256,destabilizing
+KHDRBS1,MED13L,0.06719529440712198,destabilizing
+KHDRBS1,KAZN,0.12484279797383367,destabilizing
+KHDRBS1,KANSL1,0.11114403638945422,destabilizing
+KHDRBS1,FRMD5,0.11648881468431,destabilizing
+KHDRBS1,LINC00174,0.16323930264012385,destabilizing
+KHDRBS1,PPM1E,0.1315717767110176,destabilizing
+KHDRBS1,ARL3,0.10081937943344109,destabilizing
+KHDRBS1,MBD5,0.13163167590086988,destabilizing
+KHDRBS1,ELAVL3,0.14909505980617158,destabilizing
+KHDRBS1,SLIT2,0.16632678291903213,destabilizing
+KHDRBS1,SLC8A1,0.0724427476270115,destabilizing
+KHDRBS1,CLASP1,0.146024808003421,destabilizing
+KHDRBS1,UNC5C,0.15883240548659708,destabilizing
+KHDRBS1,RC3H1,0.10105376312452169,destabilizing
+KHDRBS1,NEGR1,0.1532160290765907,destabilizing
+KHDRBS1,ENOX1,0.21970542848768457,destabilizing
+KHDRBS1,SCUBE1,0.08199670661628396,destabilizing
+KHDRBS1,GPHN,0.12905303043233238,destabilizing
+KHDRBS1,NAV3,0.15944398248936212,destabilizing
+KHDRBS1,EBF1,0.07183234777364617,destabilizing
+KHDRBS1,TOMM22,0.1932502815621073,destabilizing
+KHDRBS1,MBNL2,0.061279932388292505,destabilizing
+KHDRBS1,ANKFN1,0.0866149050777163,destabilizing
+KHDRBS1,MAGI2,0.058928113366169634,destabilizing
+KHDRBS1,LSAMP,0.09108342666704458,destabilizing
+KHDRBS1,AKAP6,0.15411807919826634,destabilizing
+KHDRBS1,TMED2,0.13131641614364278,destabilizing
+KHDRBS1,ZBTB20,0.18725390802010847,destabilizing
+KHDRBS1,GRIK2,0.14309589175134124,destabilizing
+KHDRBS1,SOX5,0.10782247141360642,destabilizing
+KHDRBS1,LRRC37A3,0.20471769647103655,destabilizing
+KHDRBS1,TMEM132C,0.05894511183102938,destabilizing
+KHDRBS1,EYS,0.10511256513344756,destabilizing
+KHDRBS1,ARID1B,0.08205068395462652,destabilizing
+KHDRBS1,PRKCE,0.08991527993850752,destabilizing
+KHDRBS1,SDK1,0.061911986509503227,destabilizing
+KHDRBS1,NRG1,0.08802039566917667,destabilizing
+KHDRBS1,MLLT3,0.22377555819197598,destabilizing
+KHDRBS1,FMN1,0.09125758250572981,destabilizing
+KHDRBS1,ADGRB3,0.08227276841191797,destabilizing
+KHDRBS1,ROBO1,0.11884892032083388,destabilizing
+KHDRBS1,SYPL1,0.09691669352679079,destabilizing
+KHDRBS1,PTPRD,0.13527276088694937,destabilizing
+KHDRBS1,FAM155A,0.18073356704791743,destabilizing
+KHDRBS1,LARP1B,0.16588555827944054,destabilizing
+KHDRBS3,TRERF1,0.12917881739110348,destabilizing
+KHDRBS3,SORCS1,0.09145194773417496,destabilizing
+KHDRBS3,COPA,0.07202343363313211,destabilizing
+KHDRBS3,FCHSD2,0.0723463817969544,destabilizing
+KHDRBS3,PDE3A,0.1550441729942679,destabilizing
+KHDRBS3,UNC79,0.15905720492508618,destabilizing
+KHDRBS3,DOC2B,0.09903363061757647,destabilizing
+KHDRBS3,TMTC2,0.15932644235300458,destabilizing
+KHDRBS3,KALRN,0.09682590134828359,destabilizing
+KHDRBS3,CHD1,0.0773954940358827,destabilizing
+KHDRBS3,UBE2E2,0.0709335961573655,destabilizing
+KHDRBS3,PPARD,0.06769943240875773,destabilizing
+KHDRBS3,RYR2,0.13525495715349564,destabilizing
+KHDRBS3,MTMR7,0.1484608586747511,destabilizing
+KHDRBS3,EPB41L4B,0.08756586040581744,destabilizing
+KHDRBS3,CACNA1B,0.09769033591229621,destabilizing
+KHDRBS3,LRRTM4,0.099602215878611,destabilizing
+KHDRBS3,SIRPA,0.12218686025530119,destabilizing
+KHDRBS3,PTEN,0.09227819117774526,destabilizing
+KHDRBS3,FRY,0.14989143626617066,destabilizing
+KHDRBS3,MACROD2,0.11517548912847816,destabilizing
+KHDRBS3,SHANK2,0.18342480717367365,destabilizing
+KHDRBS3,CDK12,0.2003693338152593,destabilizing
+KHDRBS3,RFX7,0.13242786292860867,destabilizing
+KHDRBS3,UBR5,0.06926204619566628,destabilizing
+KHDRBS3,JARID2,0.0760702355405439,destabilizing
+KHDRBS3,MPHOSPH8,0.11616251062779312,destabilizing
+KHDRBS3,DIP2C,0.10169517547182634,destabilizing
+KHDRBS3,UBR3,0.07886267854944891,destabilizing
+KHDRBS3,MGAT5,0.0645512034905535,destabilizing
+KHDRBS3,DLG2,0.10561403896857731,destabilizing
+KHDRBS3,CHST12,0.20171046166531476,destabilizing
+KHDRBS3,EML5,0.16410942193284025,destabilizing
+KHDRBS3,CENPP,0.13082783771655637,destabilizing
+KHDRBS3,PSME4,0.12178396483795002,destabilizing
+KHDRBS3,TMEM106B,0.12048860391824738,destabilizing
+KHDRBS3,EPHA5,0.1046809914029778,destabilizing
+KHDRBS3,KCNB2,0.12542186553114862,destabilizing
+KHDRBS3,SOX6,0.07613244607810543,destabilizing
+KHDRBS3,ZNF521,0.09170105353860003,destabilizing
+KHDRBS3,PLEKHA5,0.07758818222074278,destabilizing
+KHDRBS3,NOVA1,0.17700754063577886,destabilizing
+KHDRBS3,CCNY,0.12557821700542637,destabilizing
+KHDRBS3,ARIH1,0.0817721125585807,destabilizing
+KHDRBS3,EPB41L5,0.11546892199864882,destabilizing
+KHDRBS3,GPR158,0.13401372460497946,destabilizing
+KHDRBS3,NCOA2,0.10011526887241888,destabilizing
+KHDRBS3,ALK,0.14358037326110362,destabilizing
+KHDRBS3,IFT172,0.15304999102190495,destabilizing
+KHDRBS3,CCNT1,0.07272236682350129,destabilizing
+KHDRBS3,DTWD2,0.19635797814609468,destabilizing
+KHDRBS3,SIK3,0.09159564798046803,destabilizing
+KHDRBS3,CPEB3,0.15004535602808716,destabilizing
+KHDRBS3,CADM2,0.06214986626835278,destabilizing
+KHDRBS3,XKR6,0.17066014220203898,destabilizing
+KHDRBS3,RMND5A,0.06603410031950906,destabilizing
+KHDRBS3,CADPS,0.06005178090348672,destabilizing
+KHDRBS3,TCF20,0.12580596172929476,destabilizing
+KHDRBS3,CDKAL1,0.08502851630542671,destabilizing
+KHDRBS3,DGKI,0.11343999290664633,destabilizing
+KHDRBS3,EXOC6B,0.1436188491485399,destabilizing
+KHDRBS3,MAGI3,0.13125052503199244,destabilizing
+KHDRBS3,SBF2,0.06549697852246186,destabilizing
+KHDRBS3,INPP4B,0.11349541803659538,destabilizing
+KHDRBS3,ERC1,0.06263221905385251,destabilizing
+KHDRBS3,PTPRS,0.1692886027960379,destabilizing
+KHDRBS3,CBFA2T2,0.07544654661946348,destabilizing
+KHDRBS3,SPDYE3,0.07648078752154348,destabilizing
+KHDRBS3,DMD,0.19688491236745878,destabilizing
+KHDRBS3,MCU,0.10455713445584043,destabilizing
+KHDRBS3,SSH2,0.10956554167288146,destabilizing
+KHDRBS3,DOCK3,0.14045064281188016,destabilizing
+KHDRBS3,HS6ST3,0.11106189420119202,destabilizing
+KHDRBS3,LPP,0.15199629532721162,destabilizing
+KHDRBS3,STAG1,0.10107518251209983,destabilizing
+KHDRBS3,CAPZA2,0.11827319470565732,destabilizing
+KHDRBS3,ADGRL3,0.08107308346087443,destabilizing
+KHDRBS3,PHACTR1,0.0636299572491775,destabilizing
+KHDRBS3,UBE2R2,0.12127465430308237,destabilizing
+KHDRBS3,GTF2IRD1,0.1192084161833725,destabilizing
+KHDRBS3,CCBE1,0.059558818825560744,destabilizing
+KHDRBS3,TTC28,0.09955820809534248,destabilizing
+KHDRBS3,SBNO1,0.06140449998648308,destabilizing
+KHDRBS3,RIMS2,0.07592340561747629,destabilizing
+KHDRBS3,TRIO,0.05936169460857743,destabilizing
+KHDRBS3,BTBD9,0.13544991852403154,destabilizing
+KHDRBS3,CNGB1,0.14922534537658183,destabilizing
+KHDRBS3,FMN2,0.09128862893025855,destabilizing
+KHDRBS3,ENSG00000228222,0.20098527488500273,destabilizing
+KHDRBS3,PRKN,0.17815088891558417,destabilizing
+KHDRBS3,RASA2,0.12936210951044005,destabilizing
+KHDRBS3,PPP1R12B,0.11691152287335171,destabilizing
+KHDRBS3,FRMD4A,0.08833002182341278,destabilizing
+KHDRBS3,SEMA6D,0.10444399814063435,destabilizing
+KHDRBS3,WIPF2,0.13843276701606005,destabilizing
+KHDRBS3,DLEU1,0.16883812003330467,destabilizing
+KHDRBS3,TSHZ2,0.06929584545737505,destabilizing
+KHDRBS3,MED13L,0.0663850331514405,destabilizing
+KHDRBS3,KAZN,0.11269149971583163,destabilizing
+KHDRBS3,KANSL1,0.07893079076681067,destabilizing
+KHDRBS3,FRMD5,0.11045015443427644,destabilizing
+KHDRBS3,LINC00174,0.12638976351015696,destabilizing
+KHDRBS3,PPM1E,0.10801642121707832,destabilizing
+KHDRBS3,ARL3,0.07426089336928068,destabilizing
+KHDRBS3,MBD5,0.10715086367663476,destabilizing
+KHDRBS3,ELAVL3,0.11099034801456226,destabilizing
+KHDRBS3,SLIT2,0.1272894356747243,destabilizing
+KHDRBS3,SLC8A1,0.06415043081579422,destabilizing
+KHDRBS3,CLASP1,0.10615569472072987,destabilizing
+KHDRBS3,UNC5C,0.13806345482356108,destabilizing
+KHDRBS3,NEGR1,0.14707669377183225,destabilizing
+KHDRBS3,ENOX1,0.16362406648409727,destabilizing
+KHDRBS3,SCUBE1,0.07268644451873062,destabilizing
+KHDRBS3,GPHN,0.10759398716724937,destabilizing
+KHDRBS3,NAV3,0.12492001599356325,destabilizing
+KHDRBS3,TOMM22,0.13595148420358188,destabilizing
+KHDRBS3,MAGI2,0.05693432708937759,destabilizing
+KHDRBS3,LSAMP,0.0725837165303634,destabilizing
+KHDRBS3,AKAP6,0.1469984615323945,destabilizing
+KHDRBS3,TMED2,0.08221092045189807,destabilizing
+KHDRBS3,ZBTB20,0.1035254806631007,destabilizing
+KHDRBS3,GRIK2,0.11294967572859496,destabilizing
+KHDRBS3,SOX5,0.10664831961820322,destabilizing
+KHDRBS3,LRRC37A3,0.15836329103913405,destabilizing
+KHDRBS3,EYS,0.0891623747787298,destabilizing
+KHDRBS3,ARID1B,0.09777763439222095,destabilizing
+KHDRBS3,PRKCE,0.09397024532171734,destabilizing
+KHDRBS3,RBFOX1,-0.06694624343005104,stabilizing
+KHDRBS3,SDK1,0.07789453299686133,destabilizing
+KHDRBS3,NRG1,0.067975145657604,destabilizing
+KHDRBS3,MLLT3,0.18250836301664383,destabilizing
+KHDRBS3,ADGRB3,0.07043262108960043,destabilizing
+KHDRBS3,ROBO1,0.09026786608284572,destabilizing
+KHDRBS3,SYPL1,0.06134180333647837,destabilizing
+KHDRBS3,PTPRD,0.097520349507325,destabilizing
+KHDRBS3,FAM155A,0.17515746014109707,destabilizing
+KHDRBS3,LARP1B,0.13913744395490818,destabilizing
+KHSRP,CENPP,0.1224098933669183,destabilizing
+KHSRP,KCNB2,0.0924555596834182,destabilizing
+KHSRP,ALK,0.13513270058782448,destabilizing
+KHSRP,MAGI3,0.07182117149513703,destabilizing
+KHSRP,DMD,0.09123547306093771,destabilizing
+KHSRP,MCU,0.07852781265028996,destabilizing
+KHSRP,FRMD5,0.06700010474336193,destabilizing
+KHSRP,SLIT2,0.08339510029213454,destabilizing
+KHSRP,AKAP6,0.07103313409280106,destabilizing
+KHSRP,MLLT3,0.09084892000638732,destabilizing
+KHSRP,LARP1B,0.06188642887105391,destabilizing
+TIAL1,TRERF1,0.09805079145849376,destabilizing
+TIAL1,SORCS1,0.06617641030420594,destabilizing
+TIAL1,PDE3A,0.12245640675880125,destabilizing
+TIAL1,UNC79,0.11136305594869896,destabilizing
+TIAL1,DOC2B,0.0855008455939652,destabilizing
+TIAL1,TMTC2,0.09580442816525091,destabilizing
+TIAL1,KALRN,0.07831704338038799,destabilizing
+TIAL1,MTMR7,0.10851719399616129,destabilizing
+TIAL1,EIF4E,0.10639744587514426,destabilizing
+TIAL1,EPB41L4B,0.06341781331470864,destabilizing
+TIAL1,LRRTM4,0.07664882230294946,destabilizing
+TIAL1,FRY,0.11162175684750837,destabilizing
+TIAL1,MACROD2,0.07774358275078058,destabilizing
+TIAL1,SHANK2,0.15262222917425367,destabilizing
+TIAL1,CDK12,0.1220544571918559,destabilizing
+TIAL1,MPHOSPH8,0.0790976432790773,destabilizing
+TIAL1,UBR3,0.07779713398669648,destabilizing
+TIAL1,DLG2,0.06670376644371405,destabilizing
+TIAL1,CHST12,0.17191416102844873,destabilizing
+TIAL1,EML5,0.11289545216279,destabilizing
+TIAL1,PSME4,0.10711952825399254,destabilizing
+TIAL1,TMEM106B,0.12288005215191604,destabilizing
+TIAL1,EPHA5,0.0940404759915978,destabilizing
+TIAL1,KCNB2,0.11861140955735912,destabilizing
+TIAL1,ZNF83,0.07398765777120836,destabilizing
+TIAL1,SOX6,0.06828049138694582,destabilizing
+TIAL1,ZNF521,0.09304945965149625,destabilizing
+TIAL1,NOVA1,0.12489628350893407,destabilizing
+TIAL1,CCNY,0.08969464948390889,destabilizing
+TIAL1,EPB41L5,0.05579797817747257,destabilizing
+TIAL1,GPR158,0.07393585157329854,destabilizing
+TIAL1,NCOA2,0.08252046843884568,destabilizing
+TIAL1,ALK,0.14616675356715766,destabilizing
+TIAL1,SIK3,0.0916647792351936,destabilizing
+TIAL1,CPEB3,0.11684243101046633,destabilizing
+TIAL1,XKR6,0.10709801643943385,destabilizing
+TIAL1,CADPS,0.06650159711023347,destabilizing
+TIAL1,TCF20,0.10203518257790495,destabilizing
+TIAL1,EXOC6B,0.13114083520601943,destabilizing
+TIAL1,MAGI3,0.09332358386694913,destabilizing
+TIAL1,INPP4B,0.06527880595163109,destabilizing
+TIAL1,DMD,0.12829812267858945,destabilizing
+TIAL1,MCU,0.08533152464723026,destabilizing
+TIAL1,SSH2,0.07566297252657402,destabilizing
+TIAL1,DOCK3,0.09942777681785307,destabilizing
+TIAL1,LPP,0.10585120184969116,destabilizing
+TIAL1,CAPZA2,0.0802500338277097,destabilizing
+TIAL1,UBE2R2,0.07836710388181059,destabilizing
+TIAL1,GTF2IRD1,0.06752188177168342,destabilizing
+TIAL1,BTBD9,0.0841599965058956,destabilizing
+TIAL1,CNGB1,0.11434816723043262,destabilizing
+TIAL1,ENSG00000228222,0.20228837452283374,destabilizing
+TIAL1,PRKN,0.12925900012903538,destabilizing
+TIAL1,RASA2,0.09463887503909893,destabilizing
+TIAL1,FRMD4A,0.0603028505318876,destabilizing
+TIAL1,SEMA6D,0.06552132249257608,destabilizing
+TIAL1,WIPF2,0.08086279180930486,destabilizing
+TIAL1,TSHZ2,0.05600726896229708,destabilizing
+TIAL1,FRMD5,0.06812947561757654,destabilizing
+TIAL1,LINC00174,0.0724198685994053,destabilizing
+TIAL1,PPM1E,0.08522258846338952,destabilizing
+TIAL1,MBD5,0.07812377637563983,destabilizing
+TIAL1,ELAVL3,0.06753632649277169,destabilizing
+TIAL1,SLIT2,0.1112214565197603,destabilizing
+TIAL1,UNC5C,0.07991133947440539,destabilizing
+TIAL1,NEGR1,0.08466006869093384,destabilizing
+TIAL1,GPHN,0.07616951040627597,destabilizing
+TIAL1,NAV3,0.10332931606973733,destabilizing
+TIAL1,TOMM22,0.10746642357732232,destabilizing
+TIAL1,AKAP6,0.09200546780527746,destabilizing
+TIAL1,ZBTB20,0.07763823425779141,destabilizing
+TIAL1,GRIK2,0.07818760706899067,destabilizing
+TIAL1,LRRC37A3,0.09423576861043083,destabilizing
+TIAL1,EYS,0.06166130502832479,destabilizing
+TIAL1,MLLT3,0.15904863758015506,destabilizing
+TIAL1,ROBO1,0.08658627367418363,destabilizing
+TIAL1,PTPRD,0.07968378425751853,destabilizing
+TIAL1,FAM155A,0.15407382629201236,destabilizing
+TIAL1,LARP1B,0.09127076670404265,destabilizing
+ZFP36L2,TRERF1,0.12108256651675184,destabilizing
+ZFP36L2,SORCS1,0.07673092790467315,destabilizing
+ZFP36L2,PDE3A,0.11700331932039103,destabilizing
+ZFP36L2,UNC79,0.1157925531000179,destabilizing
+ZFP36L2,TMTC2,0.09823770818949785,destabilizing
+ZFP36L2,MTMR7,0.08408653471377672,destabilizing
+ZFP36L2,CACNA1B,0.06107824811753463,destabilizing
+ZFP36L2,FRY,0.11764440691750798,destabilizing
+ZFP36L2,MACROD2,0.08418003364253746,destabilizing
+ZFP36L2,SHANK2,0.12221061769921435,destabilizing
+ZFP36L2,CDK12,0.10541404765102726,destabilizing
+ZFP36L2,MPHOSPH8,0.0806125457655206,destabilizing
+ZFP36L2,DIP2C,0.07113531481490495,destabilizing
+ZFP36L2,CHST12,0.13220519231126218,destabilizing
+ZFP36L2,EML5,0.08424545509515642,destabilizing
+ZFP36L2,CENPP,0.12840212963668207,destabilizing
+ZFP36L2,PSME4,0.07306113524455424,destabilizing
+ZFP36L2,TMEM106B,0.10740651605443291,destabilizing
+ZFP36L2,EPHA5,0.07337036342885814,destabilizing
+ZFP36L2,KCNB2,0.08667312530197224,destabilizing
+ZFP36L2,ZNF83,0.07928805538176825,destabilizing
+ZFP36L2,NOVA1,0.0934413374103743,destabilizing
+ZFP36L2,CCNY,0.08344714086196943,destabilizing
+ZFP36L2,GPR158,0.09167823523496368,destabilizing
+ZFP36L2,NCOA2,0.07106511519038437,destabilizing
+ZFP36L2,SIK3,0.0795758597707648,destabilizing
+ZFP36L2,XKR6,0.09685423230204529,destabilizing
+ZFP36L2,EXOC6B,0.13546627097722744,destabilizing
+ZFP36L2,MAGI3,0.10963946191460539,destabilizing
+ZFP36L2,SPDYE3,0.08003922408030226,destabilizing
+ZFP36L2,DMD,0.13894483166828278,destabilizing
+ZFP36L2,MCU,0.07792164094382334,destabilizing
+ZFP36L2,SSH2,0.07559109684692905,destabilizing
+ZFP36L2,DOCK3,0.1233330567734994,destabilizing
+ZFP36L2,LPP,0.08924211595922535,destabilizing
+ZFP36L2,STAG1,0.06356386471870822,destabilizing
+ZFP36L2,CAPZA2,0.08037450945152325,destabilizing
+ZFP36L2,UBE2R2,0.08542759699616756,destabilizing
+ZFP36L2,GTF2IRD1,0.07861297759010705,destabilizing
+ZFP36L2,FMN2,0.06547260947075949,destabilizing
+ZFP36L2,ENSG00000228222,0.12107761978790063,destabilizing
+ZFP36L2,PRKN,0.11539584092212361,destabilizing
+ZFP36L2,RASA2,0.06557556506523403,destabilizing
+ZFP36L2,FRMD4A,0.05544175005870399,destabilizing
+ZFP36L2,SEMA6D,0.06489254041803655,destabilizing
+ZFP36L2,FRMD5,0.06358296044833935,destabilizing
+ZFP36L2,LINC00174,0.06895529603188143,destabilizing
+ZFP36L2,PPM1E,0.08393590977833712,destabilizing
+ZFP36L2,MBD5,0.07516733201849621,destabilizing
+ZFP36L2,ELAVL3,0.06869693246769158,destabilizing
+ZFP36L2,SLIT2,0.10408837523465199,destabilizing
+ZFP36L2,UNC5C,0.07766500643682582,destabilizing
+ZFP36L2,NEGR1,0.11060692737708512,destabilizing
+ZFP36L2,GPHN,0.0753888107882845,destabilizing
+ZFP36L2,NAV3,0.08791296498956726,destabilizing
+ZFP36L2,TOMM22,0.08188769749113964,destabilizing
+ZFP36L2,AKAP6,0.0974298727024502,destabilizing
+ZFP36L2,ZBTB20,0.08040954300537916,destabilizing
+ZFP36L2,GRIK2,0.06677060034583229,destabilizing
+ZFP36L2,SOX5,0.0726570978941424,destabilizing
+ZFP36L2,LRRC37A3,0.10548118692842598,destabilizing
+ZFP36L2,MLLT3,0.08879316129012732,destabilizing
+ZFP36L2,FMN1,0.05953481921276492,destabilizing
+ZFP36L2,PTPRD,0.06408488348150128,destabilizing
+ZFP36L2,LARP1B,0.08868592724390711,destabilizing
+CPEB3,CPEB3,-0.2671986301030271,stabilizing
+CPEB4,TRERF1,0.09980177544550839,destabilizing
+CPEB4,SORCS1,0.06282558831700329,destabilizing
+CPEB4,PDE3A,0.10678513749842142,destabilizing
+CPEB4,UNC79,0.07708721437779856,destabilizing
+CPEB4,DOC2B,0.06981541615110026,destabilizing
+CPEB4,MTMR7,0.1077010257953282,destabilizing
+CPEB4,EPB41L4B,0.060470607227456986,destabilizing
+CPEB4,SIRPA,0.10286358670535561,destabilizing
+CPEB4,FRY,0.09810380297882507,destabilizing
+CPEB4,MACROD2,0.06958608838812286,destabilizing
+CPEB4,RFX7,0.11981150910079046,destabilizing
+CPEB4,EML5,0.08354081063838327,destabilizing
+CPEB4,PSME4,0.06909212060856314,destabilizing
+CPEB4,TMEM106B,0.0775505268591561,destabilizing
+CPEB4,EPHA5,0.07720751786451042,destabilizing
+CPEB4,ZNF83,0.06944470793333032,destabilizing
+CPEB4,NCOA2,0.06895949388219648,destabilizing
+CPEB4,IFT172,0.07458626437183508,destabilizing
+CPEB4,SIK3,0.08224347617482959,destabilizing
+CPEB4,XKR6,0.08919633388290198,destabilizing
+CPEB4,EXOC6B,0.10951245461165046,destabilizing
+CPEB4,MAGI3,0.0797158069358072,destabilizing
+CPEB4,SPDYE3,0.06976648104474216,destabilizing
+CPEB4,DMD,0.13144584119172945,destabilizing
+CPEB4,MCU,0.06768533194569044,destabilizing
+CPEB4,LPP,0.10096064691090138,destabilizing
+CPEB4,GTF2IRD1,0.08434696967098208,destabilizing
+CPEB4,CNGB1,0.09734591435251767,destabilizing
+CPEB4,FMN2,0.08597453997160157,destabilizing
+CPEB4,PRKN,0.1300473263280628,destabilizing
+CPEB4,RASA2,0.06850495207050633,destabilizing
+CPEB4,KAZN,0.10121371847333313,destabilizing
+CPEB4,LINC00174,0.07340439979241685,destabilizing
+CPEB4,SLIT2,0.12458281459874436,destabilizing
+CPEB4,UNC5C,0.0781263017622225,destabilizing
+CPEB4,NEGR1,0.07740873358902547,destabilizing
+CPEB4,GPHN,0.06342745626304634,destabilizing
+CPEB4,ZBTB20,0.07408736941201835,destabilizing
+CPEB4,LRRC37A3,0.10096498328349887,destabilizing
+CPEB4,EYS,0.05905133100383057,destabilizing
+CPEB4,MLLT3,0.10561695394756607,destabilizing
+CPEB4,ROBO1,0.07242480381430257,destabilizing
+CPEB4,LARP1B,0.0842278116791711,destabilizing
+PUM1,DLG2,0.062022410495528035,destabilizing
+PUM1,IFT172,0.0702744090356348,destabilizing
+PUM1,MAGI3,0.07175485009483636,destabilizing
+PUM1,DMD,0.07451899191810767,destabilizing
+PUM1,SSH2,0.0631416874951458,destabilizing
+PUM1,DOCK3,0.094356326609472,destabilizing
+PUM1,LRRC37A3,0.08081978922370381,destabilizing
+PUM1,LARP1B,0.06819512198788277,destabilizing
+PUM2,CDK12,0.09318759651184771,destabilizing
+PUM2,EML5,0.08231556303443835,destabilizing
+PUM2,CENPP,0.14614837970210443,destabilizing
+PUM2,PUM2,-0.37934055613401985,stabilizing
+PUM2,ALK,0.1523917225758456,destabilizing
+PUM2,EXOC6B,0.08492088711615446,destabilizing
+PUM2,DMD,0.07985682548992289,destabilizing
+PUM2,WIPF2,0.08734661177587236,destabilizing
+PUM2,ZBTB20,0.0724410467298846,destabilizing
+PUM2,MLLT3,0.09283556286796296,destabilizing
+STAU1,TRERF1,0.17906313010110567,destabilizing
+STAU1,SORCS1,0.10667423113957088,destabilizing
+STAU1,COPA,0.06111345154091746,destabilizing
+STAU1,FCHSD2,0.07865316602016004,destabilizing
+STAU1,PDE3A,0.1671060432698347,destabilizing
+STAU1,UNC79,0.17137193185595564,destabilizing
+STAU1,DOC2B,0.12279803213062156,destabilizing
+STAU1,TMTC2,0.1487111925808709,destabilizing
+STAU1,KALRN,0.12073853348013845,destabilizing
+STAU1,CHD1,0.09653297106870876,destabilizing
+STAU1,UBE2E2,0.06579145766137998,destabilizing
+STAU1,PPARD,0.08351264712960184,destabilizing
+STAU1,BRAF,0.055101030303389864,destabilizing
+STAU1,RYR2,0.1692550850908079,destabilizing
+STAU1,MTMR7,0.17189125070570074,destabilizing
+STAU1,EIF4E,0.16416256588391032,destabilizing
+STAU1,SOX11,0.07571978693701507,destabilizing
+STAU1,EPB41L4B,0.10465543199465298,destabilizing
+STAU1,CACNA1B,0.11673933908016332,destabilizing
+STAU1,LRRTM4,0.11843201182591231,destabilizing
+STAU1,SIRPA,0.15746367933082586,destabilizing
+STAU1,PTEN,0.08673921224615404,destabilizing
+STAU1,FRY,0.1687353472573027,destabilizing
+STAU1,MACROD2,0.16893278012278126,destabilizing
+STAU1,FOXN3,0.06591709536570692,destabilizing
+STAU1,SHANK2,0.21951162797244703,destabilizing
+STAU1,CDK12,0.2281358235985523,destabilizing
+STAU1,RFX7,0.1439084112620242,destabilizing
+STAU1,UBR5,0.08972825062990615,destabilizing
+STAU1,JARID2,0.08473490901904604,destabilizing
+STAU1,MPHOSPH8,0.13144080527700347,destabilizing
+STAU1,DIP2C,0.10585675825662877,destabilizing
+STAU1,ZNF423,0.06732078607613076,destabilizing
+STAU1,UBR3,0.10836197988162792,destabilizing
+STAU1,MGAT5,0.06448322622189735,destabilizing
+STAU1,DLG2,0.11510159621557478,destabilizing
+STAU1,CHST12,0.2784319815824516,destabilizing
+STAU1,EML5,0.18068896290362751,destabilizing
+STAU1,CENPP,0.19380718520771403,destabilizing
+STAU1,PSME4,0.16336105829223938,destabilizing
+STAU1,TMEM106B,0.14828234926522288,destabilizing
+STAU1,EPHA5,0.10893935819000007,destabilizing
+STAU1,KCNB2,0.15575063929832328,destabilizing
+STAU1,ZNF83,0.11500991175418526,destabilizing
+STAU1,SOX6,0.0740380615206838,destabilizing
+STAU1,ZNF521,0.1319077131367733,destabilizing
+STAU1,PLEKHA5,0.09818310994152567,destabilizing
+STAU1,NOVA1,0.18919630130172624,destabilizing
+STAU1,CCNY,0.15742642596021306,destabilizing
+STAU1,ARIH1,0.14112903488028272,destabilizing
+STAU1,EPB41L5,0.11120583095169741,destabilizing
+STAU1,GPR158,0.16288421546136336,destabilizing
+STAU1,NCOA2,0.10777015430295506,destabilizing
+STAU1,ALK,0.13498813424060374,destabilizing
+STAU1,ACACA,0.08631613390381138,destabilizing
+STAU1,IFT172,0.1457668753426052,destabilizing
+STAU1,CCNT1,0.09027317361542839,destabilizing
+STAU1,DTWD2,0.18637069813742901,destabilizing
+STAU1,SIK3,0.1285645654707455,destabilizing
+STAU1,CPEB3,0.18098585316611868,destabilizing
+STAU1,CADM2,0.08352612591021139,destabilizing
+STAU1,XKR6,0.19340984972609854,destabilizing
+STAU1,RMND5A,0.06259943666704283,destabilizing
+STAU1,CADPS,0.0857642396640679,destabilizing
+STAU1,FGF13,0.0593549218414877,destabilizing
+STAU1,TCF20,0.17737558461907224,destabilizing
+STAU1,CDKAL1,0.06782318475176394,destabilizing
+STAU1,DGKI,0.10662941006921381,destabilizing
+STAU1,EXOC6B,0.18766923625339843,destabilizing
+STAU1,MAGI3,0.14072624900941583,destabilizing
+STAU1,SBF2,0.08689093991171985,destabilizing
+STAU1,INPP4B,0.14847399719716461,destabilizing
+STAU1,PTPRS,0.15229270613294868,destabilizing
+STAU1,CBFA2T2,0.10133915567916449,destabilizing
+STAU1,SPDYE3,0.12842830588276075,destabilizing
+STAU1,TMEM178B,0.08002558526404649,destabilizing
+STAU1,DMD,0.23437908821770267,destabilizing
+STAU1,MCU,0.13594572452268575,destabilizing
+STAU1,SSH2,0.11005497191621604,destabilizing
+STAU1,DOCK3,0.1825000440830059,destabilizing
+STAU1,HS6ST3,0.17057713389360654,destabilizing
+STAU1,LPP,0.15782849034390756,destabilizing
+STAU1,STAG1,0.11523810187392318,destabilizing
+STAU1,CAPZA2,0.15978102165022562,destabilizing
+STAU1,ADGRL3,0.07650547173867867,destabilizing
+STAU1,PHACTR1,0.06202166985422303,destabilizing
+STAU1,UBE2R2,0.17154288750155364,destabilizing
+STAU1,GTF2IRD1,0.1509382441565033,destabilizing
+STAU1,CCBE1,0.07475712088694271,destabilizing
+STAU1,TTC28,0.10677633149791693,destabilizing
+STAU1,SBNO1,0.06419194318931398,destabilizing
+STAU1,RIMS2,0.08579553283756924,destabilizing
+STAU1,IGF1R,0.060872795793883216,destabilizing
+STAU1,TRIO,0.06242076561189917,destabilizing
+STAU1,KCND2,0.06486787558928192,destabilizing
+STAU1,BTBD9,0.14622132203396948,destabilizing
+STAU1,CNGB1,0.17855285660511286,destabilizing
+STAU1,FMN2,0.12559782352915486,destabilizing
+STAU1,ENSG00000228222,0.17756717646196785,destabilizing
+STAU1,ATXN1,0.06501854817654905,destabilizing
+STAU1,PRKN,0.19245763786664402,destabilizing
+STAU1,RASA2,0.15012902221856603,destabilizing
+STAU1,PPP1R12B,0.1002413540523904,destabilizing
+STAU1,FRMD4A,0.10118189587083651,destabilizing
+STAU1,CAMK1D,0.06482687569737783,destabilizing
+STAU1,PARD3,0.053242517138758674,destabilizing
+STAU1,SEMA6D,0.12162997911870238,destabilizing
+STAU1,WIPF2,0.1492276581566547,destabilizing
+STAU1,DLEU1,0.18837141318624856,destabilizing
+STAU1,TSHZ2,0.09798155358072314,destabilizing
+STAU1,MED13L,0.09633853856005979,destabilizing
+STAU1,KAZN,0.151680880964553,destabilizing
+STAU1,KANSL1,0.07765265490392477,destabilizing
+STAU1,FRMD5,0.15066516699757299,destabilizing
+STAU1,LINC00174,0.12386471848160467,destabilizing
+STAU1,PPM1E,0.14868475796745098,destabilizing
+STAU1,ARL3,0.08972724200368078,destabilizing
+STAU1,MBD5,0.10760293655657406,destabilizing
+STAU1,ELAVL3,0.13760491123809906,destabilizing
+STAU1,SLIT2,0.1858800869864348,destabilizing
+STAU1,CLASP1,0.0829161516838953,destabilizing
+STAU1,UNC5C,0.12918212077797758,destabilizing
+STAU1,CACNA2D3,-0.061803226344045,stabilizing
+STAU1,RC3H1,0.1091025471500096,destabilizing
+STAU1,NEGR1,0.13228948942574856,destabilizing
+STAU1,ENOX1,0.18379843685561884,destabilizing
+STAU1,SCUBE1,0.06489341531937286,destabilizing
+STAU1,GPHN,0.10059003146634234,destabilizing
+STAU1,NAV3,0.14525683007726148,destabilizing
+STAU1,EBF1,0.06339664271770241,destabilizing
+STAU1,TOMM22,0.1685182326263581,destabilizing
+STAU1,MBNL2,0.0790174462062726,destabilizing
+STAU1,ANKFN1,0.05725751863840793,destabilizing
+STAU1,MAGI2,0.07839377495864545,destabilizing
+STAU1,LSAMP,0.08319334350811211,destabilizing
+STAU1,AKAP6,0.16405090184420584,destabilizing
+STAU1,TMED2,0.10842821475744709,destabilizing
+STAU1,ZBTB20,0.12754175109036142,destabilizing
+STAU1,GRIK2,0.1362915887965353,destabilizing
+STAU1,SOX5,0.09026764218346532,destabilizing
+STAU1,LRRC37A3,0.19364245760039783,destabilizing
+STAU1,EYS,0.1050075187105036,destabilizing
+STAU1,ARID1B,0.08394630303465006,destabilizing
+STAU1,PRKCE,0.09655525227876995,destabilizing
+STAU1,RBFOX1,-0.09754743313749491,stabilizing
+STAU1,SDK1,0.08242170473958751,destabilizing
+STAU1,MLLT3,0.19262347205756994,destabilizing
+STAU1,FMN1,0.08052509159199284,destabilizing
+STAU1,ADGRB3,0.08390152007293458,destabilizing
+STAU1,ROBO1,0.12753288453775863,destabilizing
+STAU1,SYPL1,0.07066495975140998,destabilizing
+STAU1,PTPRD,0.12545438244486176,destabilizing
+STAU1,FAM155A,0.14025497632097067,destabilizing
+STAU1,LARP1B,0.12939402110683826,destabilizing
+STAU2,TRERF1,0.08847366478147801,destabilizing
+STAU2,SORCS1,0.06629407803941628,destabilizing
+STAU2,PDE3A,0.12820575287483946,destabilizing
+STAU2,UNC79,0.11000771854696341,destabilizing
+STAU2,DOC2B,0.062447046216413754,destabilizing
+STAU2,TMTC2,0.12330411513744385,destabilizing
+STAU2,RYR2,0.13941956516768902,destabilizing
+STAU2,MTMR7,0.08726544757074296,destabilizing
+STAU2,EPB41L4B,0.06116204722294149,destabilizing
+STAU2,CACNA1B,0.058657266288466466,destabilizing
+STAU2,LRRTM4,0.060610737791947616,destabilizing
+STAU2,SIRPA,0.0990010484456862,destabilizing
+STAU2,FRY,0.10178313083218486,destabilizing
+STAU2,MACROD2,0.12100741774499628,destabilizing
+STAU2,SHANK2,0.12372330759532527,destabilizing
+STAU2,CDK12,0.12912950107920865,destabilizing
+STAU2,UBR5,0.06940666653222483,destabilizing
+STAU2,JARID2,0.053635883011313695,destabilizing
+STAU2,MPHOSPH8,0.07593620090639518,destabilizing
+STAU2,DIP2C,0.08600037297371285,destabilizing
+STAU2,UBR3,0.07125840847443843,destabilizing
+STAU2,DLG2,0.0678044032206622,destabilizing
+STAU2,EML5,0.11233933175436349,destabilizing
+STAU2,PSME4,0.09882928163375507,destabilizing
+STAU2,TMEM106B,0.0922396896026284,destabilizing
+STAU2,EPHA5,0.09132781457007023,destabilizing
+STAU2,KCNB2,0.1008269572915906,destabilizing
+STAU2,ZNF521,0.07755612880919822,destabilizing
+STAU2,NOVA1,0.11012405509540056,destabilizing
+STAU2,CCNY,0.13410605251968302,destabilizing
+STAU2,ARIH1,0.08384070369903261,destabilizing
+STAU2,EPB41L5,0.059354935847069974,destabilizing
+STAU2,GPR158,0.09706538611567941,destabilizing
+STAU2,NCOA2,0.0729802642902667,destabilizing
+STAU2,ALK,0.10199512509108928,destabilizing
+STAU2,IFT172,0.09293416099676696,destabilizing
+STAU2,CCNT1,0.06567621430884307,destabilizing
+STAU2,SIK3,0.08242889201261268,destabilizing
+STAU2,CPEB3,0.10738511902365742,destabilizing
+STAU2,XKR6,0.10967354488435171,destabilizing
+STAU2,TCF20,0.1028841995182487,destabilizing
+STAU2,DGKI,0.08029838947908123,destabilizing
+STAU2,EXOC6B,0.12288360683608315,destabilizing
+STAU2,MAGI3,0.0959832124381851,destabilizing
+STAU2,INPP4B,0.0878674264056594,destabilizing
+STAU2,CBFA2T2,0.058251725415345686,destabilizing
+STAU2,SPDYE3,0.08320749292771433,destabilizing
+STAU2,DMD,0.1385458849904453,destabilizing
+STAU2,MCU,0.06659709276862368,destabilizing
+STAU2,SSH2,0.07004172673081942,destabilizing
+STAU2,DOCK3,0.11918247613171314,destabilizing
+STAU2,LPP,0.1226429146483643,destabilizing
+STAU2,STAG1,0.0800643118156107,destabilizing
+STAU2,UBE2R2,0.08616029768762666,destabilizing
+STAU2,GTF2IRD1,0.0815915360829945,destabilizing
+STAU2,CCBE1,0.054740654561590864,destabilizing
+STAU2,SBNO1,0.058601278690461236,destabilizing
+STAU2,BTBD9,0.09792221623511156,destabilizing
+STAU2,CNGB1,0.09494624717956851,destabilizing
+STAU2,FMN2,0.07222948880438242,destabilizing
+STAU2,ENSG00000228222,0.15177185067635932,destabilizing
+STAU2,PRKN,0.10180636362157364,destabilizing
+STAU2,RASA2,0.10538527211564923,destabilizing
+STAU2,FRMD4A,0.06520552569365558,destabilizing
+STAU2,SEMA6D,0.06395060081236208,destabilizing
+STAU2,WIPF2,0.07405832209568744,destabilizing
+STAU2,TSHZ2,0.06379232869859146,destabilizing
+STAU2,KAZN,0.07442115352714279,destabilizing
+STAU2,FRMD5,0.08632702315613432,destabilizing
+STAU2,LINC00174,0.061258606680646796,destabilizing
+STAU2,PPM1E,0.08117484938667228,destabilizing
+STAU2,MBD5,0.07206157855125325,destabilizing
+STAU2,ELAVL3,0.08871067889644073,destabilizing
+STAU2,SLIT2,0.11586251140461315,destabilizing
+STAU2,UNC5C,0.0958792848728284,destabilizing
+STAU2,GPHN,0.0769581855724874,destabilizing
+STAU2,NAV3,0.09679020772123027,destabilizing
+STAU2,TOMM22,0.08470695110245091,destabilizing
+STAU2,MAGI2,0.056114294883372696,destabilizing
+STAU2,LSAMP,0.054937987114078726,destabilizing
+STAU2,AKAP6,0.0820198047874418,destabilizing
+STAU2,ZBTB20,0.07738616123716267,destabilizing
+STAU2,GRIK2,0.0860576466909638,destabilizing
+STAU2,LRRC37A3,0.10200024699999012,destabilizing
+STAU2,SDK1,0.08212372549565886,destabilizing
+STAU2,MLLT3,0.11779936644215164,destabilizing
+STAU2,FMN1,0.06047276669976803,destabilizing
+STAU2,ROBO1,0.07348869483246036,destabilizing
+STAU2,PTPRD,0.07574690643155209,destabilizing
+STAU2,FAM155A,0.1010535168599385,destabilizing
+STAU2,LARP1B,0.08387138040257731,destabilizing
+UPF1,KCNB2,0.08564240941890415,destabilizing
+UPF2,TRERF1,0.11495019689368047,destabilizing
+UPF2,SORCS1,0.07759018852004562,destabilizing
+UPF2,UNC79,0.09526124502453354,destabilizing
+UPF2,UBE2E2,0.05850249077585802,destabilizing
+UPF2,MTMR7,0.12353892240878607,destabilizing
+UPF2,EIF4E,0.10437774354630844,destabilizing
+UPF2,LRRTM4,0.0581112031149767,destabilizing
+UPF2,MACROD2,0.07330789410031034,destabilizing
+UPF2,SHANK2,0.10487088327973575,destabilizing
+UPF2,CDK12,0.09272066310938765,destabilizing
+UPF2,MPHOSPH8,0.0644843789934093,destabilizing
+UPF2,DIP2C,0.0683486093827375,destabilizing
+UPF2,CHST12,0.14087264869856864,destabilizing
+UPF2,EML5,0.11074468761853591,destabilizing
+UPF2,PSME4,0.11262893571606221,destabilizing
+UPF2,KCNB2,0.0895821065596533,destabilizing
+UPF2,NOVA1,0.09407491047463892,destabilizing
+UPF2,CCNY,0.08542632525703618,destabilizing
+UPF2,ARIH1,0.06126520412788809,destabilizing
+UPF2,EPB41L5,0.057093367172316396,destabilizing
+UPF2,GPR158,0.08036482274641381,destabilizing
+UPF2,SIK3,0.07570477584136624,destabilizing
+UPF2,TCF20,0.09600111418253145,destabilizing
+UPF2,EXOC6B,0.11656218866731208,destabilizing
+UPF2,MAGI3,0.07847383144492413,destabilizing
+UPF2,SPDYE3,0.067528568443593,destabilizing
+UPF2,DMD,0.12860724417227848,destabilizing
+UPF2,MCU,0.08566944440478988,destabilizing
+UPF2,DOCK3,0.0820045492087953,destabilizing
+UPF2,HS6ST3,0.09068711256981905,destabilizing
+UPF2,GTF2IRD1,0.0586072894686413,destabilizing
+UPF2,CNGB1,0.10593314463758861,destabilizing
+UPF2,ENSG00000228222,0.12232349295845889,destabilizing
+UPF2,PRKN,0.11025536939958648,destabilizing
+UPF2,RASA2,0.06877558729846112,destabilizing
+UPF2,FRMD4A,0.0625966626391247,destabilizing
+UPF2,WIPF2,0.08742354214280598,destabilizing
+UPF2,LINC00174,0.07891102009068232,destabilizing
+UPF2,ELAVL3,0.07077745608323671,destabilizing
+UPF2,SLIT2,0.10065359779945411,destabilizing
+UPF2,UNC5C,0.08385430396789133,destabilizing
+UPF2,NAV3,0.09360243481225701,destabilizing
+UPF2,GRIK2,0.060309407842188155,destabilizing
+UPF2,LRRC37A3,0.10757397791705536,destabilizing
+UPF2,PRKCE,0.08765818662210398,destabilizing
+UPF2,MLLT3,0.09774979005731631,destabilizing
+UPF2,ROBO1,0.0703613791809604,destabilizing
+UPF2,LARP1B,0.0691012653072394,destabilizing
+UPF3B,TRERF1,0.10273347284487871,destabilizing
+UPF3B,UNC79,0.09390399959245424,destabilizing
+UPF3B,DOC2B,0.06068649700033719,destabilizing
+UPF3B,PPARD,0.0671949261671757,destabilizing
+UPF3B,MTMR7,0.09372762265015164,destabilizing
+UPF3B,EPB41L4B,0.06238518614446834,destabilizing
+UPF3B,LRRTM4,0.06932910887025884,destabilizing
+UPF3B,FRY,0.10080189609180562,destabilizing
+UPF3B,MACROD2,0.09175179546854098,destabilizing
+UPF3B,CDK12,0.09454219185456672,destabilizing
+UPF3B,RFX7,0.09546012443848223,destabilizing
+UPF3B,MPHOSPH8,0.07955508107515606,destabilizing
+UPF3B,DIP2C,0.06905894873087447,destabilizing
+UPF3B,CHST12,0.11519840310714989,destabilizing
+UPF3B,EML5,0.08317158088644212,destabilizing
+UPF3B,CENPP,0.1386693945337683,destabilizing
+UPF3B,TMEM106B,0.10853901635220356,destabilizing
+UPF3B,KCNB2,0.0882468000541905,destabilizing
+UPF3B,ZNF521,0.07580442197568958,destabilizing
+UPF3B,CCNY,0.09460687264587302,destabilizing
+UPF3B,ARIH1,0.06289781164563725,destabilizing
+UPF3B,EPB41L5,0.05571036018059246,destabilizing
+UPF3B,GPR158,0.08961846187666715,destabilizing
+UPF3B,ALK,0.12214810557149325,destabilizing
+UPF3B,IFT172,0.07685327380512486,destabilizing
+UPF3B,CCNT1,0.059316871009675386,destabilizing
+UPF3B,DTWD2,0.1510696071979053,destabilizing
+UPF3B,CPEB3,0.10440869670069429,destabilizing
+UPF3B,XKR6,0.10038345811615347,destabilizing
+UPF3B,DGKI,0.0717036156530807,destabilizing
+UPF3B,EXOC6B,0.11082288833815505,destabilizing
+UPF3B,MAGI3,0.07755075562740855,destabilizing
+UPF3B,INPP4B,0.06495573361337363,destabilizing
+UPF3B,DMD,0.11476722464651314,destabilizing
+UPF3B,SSH2,0.0722836673014703,destabilizing
+UPF3B,DOCK3,0.10103982367629717,destabilizing
+UPF3B,CAPZA2,0.07464656796642294,destabilizing
+UPF3B,ADGRL3,0.06609341432934238,destabilizing
+UPF3B,UBE2R2,0.0790411446752767,destabilizing
+UPF3B,PRKN,0.10751009650261971,destabilizing
+UPF3B,RASA2,0.07805861718886546,destabilizing
+UPF3B,WIPF2,0.07118630930714621,destabilizing
+UPF3B,FRMD5,0.0750940196459429,destabilizing
+UPF3B,LINC00174,0.07471978901624733,destabilizing
+UPF3B,MBD5,0.06811850374817563,destabilizing
+UPF3B,ELAVL3,0.07993168523752785,destabilizing
+UPF3B,SLIT2,0.13291195803276135,destabilizing
+UPF3B,CLASP1,0.07337017732436264,destabilizing
+UPF3B,UNC5C,0.08975638823280946,destabilizing
+UPF3B,NEGR1,0.0755720453324762,destabilizing
+UPF3B,NAV3,0.10703876574068773,destabilizing
+UPF3B,TMED2,0.06549497613423956,destabilizing
+UPF3B,ZBTB20,0.07255011871163948,destabilizing
+UPF3B,GRIK2,0.07120400837336284,destabilizing
+UPF3B,LRRC37A3,0.10720041831141669,destabilizing
+UPF3B,RBFOX1,-0.05781418891270059,stabilizing
+UPF3B,MLLT3,0.09149976889055707,destabilizing
+UPF3B,PTPRD,0.056690729888086024,destabilizing
+UPF3B,LARP1B,0.06535841924988366,destabilizing
+SMG1,MACROD2,0.07086750948177797,destabilizing
+DIS3L2,TRERF1,0.08837991042264376,destabilizing
+DIS3L2,SORCS1,0.06399619688271693,destabilizing
+DIS3L2,PDE3A,0.09640668652310162,destabilizing
+DIS3L2,UNC79,0.09242007385770826,destabilizing
+DIS3L2,DOC2B,0.06490269480089894,destabilizing
+DIS3L2,TMTC2,0.07856473770813445,destabilizing
+DIS3L2,RYR2,0.12475421982900455,destabilizing
+DIS3L2,MTMR7,0.09214487512226567,destabilizing
+DIS3L2,MACROD2,0.068996679652712,destabilizing
+DIS3L2,SHANK2,0.10391705179200915,destabilizing
+DIS3L2,CDK12,0.08455420493011001,destabilizing
+DIS3L2,RFX7,0.1119720665256944,destabilizing
+DIS3L2,MPHOSPH8,0.07202330510300868,destabilizing
+DIS3L2,CHST12,0.13969309928763055,destabilizing
+DIS3L2,EML5,0.08057932110677422,destabilizing
+DIS3L2,PSME4,0.09154721550339553,destabilizing
+DIS3L2,ZNF521,0.07326986200686132,destabilizing
+DIS3L2,CCNY,0.09616031045339495,destabilizing
+DIS3L2,ARIH1,0.061137065670631985,destabilizing
+DIS3L2,GPR158,0.08186884393480233,destabilizing
+DIS3L2,NCOA2,0.06679350917183698,destabilizing
+DIS3L2,XKR6,0.08355888412045896,destabilizing
+DIS3L2,EXOC6B,0.08758643117547557,destabilizing
+DIS3L2,DMD,0.1210564030192465,destabilizing
+DIS3L2,LPP,0.10559081055870896,destabilizing
+DIS3L2,STAG1,0.06931782809347099,destabilizing
+DIS3L2,PHACTR1,0.06014863500145742,destabilizing
+DIS3L2,GTF2IRD1,0.057831256436598956,destabilizing
+DIS3L2,BTBD9,0.0770311741987768,destabilizing
+DIS3L2,CNGB1,0.08880396718127066,destabilizing
+DIS3L2,ENSG00000228222,0.15524943483028847,destabilizing
+DIS3L2,PRKN,0.10158621215353865,destabilizing
+DIS3L2,RASA2,0.06468934572285379,destabilizing
+DIS3L2,SEMA6D,0.05942376725566453,destabilizing
+DIS3L2,WIPF2,0.06893692745883821,destabilizing
+DIS3L2,FRMD5,0.0645442704615214,destabilizing
+DIS3L2,PPM1E,0.0817279107609809,destabilizing
+DIS3L2,MBD5,0.05813234152135872,destabilizing
+DIS3L2,ELAVL3,0.07072879088118951,destabilizing
+DIS3L2,SLIT2,0.09405996709955487,destabilizing
+DIS3L2,UNC5C,0.07283987246635094,destabilizing
+DIS3L2,RC3H1,0.06862189346466303,destabilizing
+DIS3L2,NEGR1,0.08039621288352643,destabilizing
+DIS3L2,GPHN,0.06665662391046297,destabilizing
+DIS3L2,LSAMP,0.0558088370591258,destabilizing
+DIS3L2,AKAP6,0.07215188458865583,destabilizing
+DIS3L2,MLLT3,0.08986952902528618,destabilizing
+DIS3L2,ADGRB3,0.06984719098764912,destabilizing
+DIS3L2,PTPRD,0.06593884229425163,destabilizing
+XRN1,GPR158,0.07348234316702479,destabilizing
+XRN1,MAGI3,0.06739699755084762,destabilizing
+XRN1,DMD,0.10222796563129441,destabilizing
+XRN1,RASA2,0.07483733312130099,destabilizing
+XRN1,FRMD5,0.0812096739456312,destabilizing
+XRN1,UNC5C,0.06278503006265199,destabilizing
+XRN1,MLLT3,0.08242045204564441,destabilizing
+XRN1,LARP1B,0.06948691974041774,destabilizing
+XRN2,TRERF1,0.08636547785217852,destabilizing
+XRN2,PDE3A,0.0998273565701556,destabilizing
+XRN2,UNC79,0.08118090817102674,destabilizing
+XRN2,DOC2B,0.06268568268642959,destabilizing
+XRN2,TMTC2,0.07655255220305052,destabilizing
+XRN2,CACNA1B,0.061843132901061,destabilizing
+XRN2,FRY,0.09268926964827132,destabilizing
+XRN2,MACROD2,0.07903645456378088,destabilizing
+XRN2,SHANK2,0.1251526688152679,destabilizing
+XRN2,CDK12,0.12482758957526044,destabilizing
+XRN2,DLG2,0.06500507513100458,destabilizing
+XRN2,CHST12,0.1452481318508315,destabilizing
+XRN2,PSME4,0.073368465068643,destabilizing
+XRN2,TMEM106B,0.11239213538995192,destabilizing
+XRN2,ZNF521,0.0804023884006494,destabilizing
+XRN2,PLEKHA5,0.06458363093154082,destabilizing
+XRN2,ARIH1,0.06554903667512718,destabilizing
+XRN2,EPB41L5,0.06040920985365302,destabilizing
+XRN2,IFT172,0.07645914366868613,destabilizing
+XRN2,CCNT1,0.0596898232511033,destabilizing
+XRN2,SIK3,0.07859214663041138,destabilizing
+XRN2,XKR6,0.0948486236012232,destabilizing
+XRN2,CDKAL1,0.07912579126484656,destabilizing
+XRN2,DGKI,0.07683731538584963,destabilizing
+XRN2,EXOC6B,0.10749794027189487,destabilizing
+XRN2,MAGI3,0.09898157808462749,destabilizing
+XRN2,PTPRS,0.12397284821628808,destabilizing
+XRN2,SPDYE3,0.07549762343270704,destabilizing
+XRN2,DMD,0.10484579754614308,destabilizing
+XRN2,SSH2,0.0923507465455573,destabilizing
+XRN2,DOCK3,0.08733706719798073,destabilizing
+XRN2,HS6ST3,0.09026168034394706,destabilizing
+XRN2,STAG1,0.06621772995840607,destabilizing
+XRN2,UBE2R2,0.08782779768069005,destabilizing
+XRN2,GTF2IRD1,0.05984557624219921,destabilizing
+XRN2,SBNO1,0.059734440054559995,destabilizing
+XRN2,ENSG00000228222,0.13254675209146674,destabilizing
+XRN2,RASA2,0.08501965768511055,destabilizing
+XRN2,SEMA6D,0.07240907653520243,destabilizing
+XRN2,DLEU1,0.11078259400252669,destabilizing
+XRN2,FRMD5,0.06812786046344725,destabilizing
+XRN2,LINC00174,0.06322028322596188,destabilizing
+XRN2,MBD5,0.06982268564492819,destabilizing
+XRN2,ELAVL3,0.09713315865858575,destabilizing
+XRN2,SLIT2,0.09572190304481952,destabilizing
+XRN2,UNC5C,0.08686737656887752,destabilizing
+XRN2,NEGR1,0.08399428223364569,destabilizing
+XRN2,TOMM22,0.08542346040386058,destabilizing
+XRN2,ZBTB20,0.09445815315305198,destabilizing
+XRN2,SOX5,0.0730238732457323,destabilizing
+XRN2,LRRC37A3,0.08475004953223254,destabilizing
+XRN2,MLLT3,0.10958674770945523,destabilizing
+XRN2,PTPRD,0.06578633647653724,destabilizing
+XRN2,FAM155A,0.11878655838076468,destabilizing
+XRN2,LARP1B,0.08095326682748402,destabilizing
+EXOSC10,TRERF1,0.08446525669364215,destabilizing
+EXOSC10,UNC79,0.09807129122133852,destabilizing
+EXOSC10,TMTC2,0.09530630439938009,destabilizing
+EXOSC10,KALRN,0.06958466892892606,destabilizing
+EXOSC10,MTMR7,0.11961948642268486,destabilizing
+EXOSC10,CACNA1B,0.06924796106137528,destabilizing
+EXOSC10,PTEN,0.08599241684819257,destabilizing
+EXOSC10,FRY,0.08997571665726538,destabilizing
+EXOSC10,MACROD2,0.0687358949715396,destabilizing
+EXOSC10,SHANK2,0.12422270134462363,destabilizing
+EXOSC10,CDK12,0.1255134075964093,destabilizing
+EXOSC10,RFX7,0.10161893678068479,destabilizing
+EXOSC10,MPHOSPH8,0.08048138498753599,destabilizing
+EXOSC10,DLG2,0.07169706117901371,destabilizing
+EXOSC10,CHST12,0.13398838356084689,destabilizing
+EXOSC10,EML5,0.10679497649028358,destabilizing
+EXOSC10,CENPP,0.15705452234426281,destabilizing
+EXOSC10,TMEM106B,0.08630393833110765,destabilizing
+EXOSC10,SOX6,0.08277467831747927,destabilizing
+EXOSC10,ZNF521,0.09437930955359274,destabilizing
+EXOSC10,CCNY,0.0930492851432147,destabilizing
+EXOSC10,EPB41L5,0.06344471548765758,destabilizing
+EXOSC10,GPR158,0.07480218357757948,destabilizing
+EXOSC10,ALK,0.11297153532924166,destabilizing
+EXOSC10,IFT172,0.07593137396379958,destabilizing
+EXOSC10,DTWD2,0.1384647930778423,destabilizing
+EXOSC10,CPEB3,0.10963873076509506,destabilizing
+EXOSC10,DGKI,0.07513761519644854,destabilizing
+EXOSC10,MAGI3,0.08925426867426081,destabilizing
+EXOSC10,DMD,0.10887152397674976,destabilizing
+EXOSC10,SSH2,0.0772660405637974,destabilizing
+EXOSC10,DOCK3,0.08365576550463692,destabilizing
+EXOSC10,HS6ST3,0.09022111086569101,destabilizing
+EXOSC10,CAPZA2,0.06773234063115076,destabilizing
+EXOSC10,UBE2R2,0.08943273598607411,destabilizing
+EXOSC10,GTF2IRD1,0.07598166616897256,destabilizing
+EXOSC10,SBNO1,0.06051991172873712,destabilizing
+EXOSC10,BTBD9,0.07570062563614631,destabilizing
+EXOSC10,CNGB1,0.0931644525790277,destabilizing
+EXOSC10,ENSG00000228222,0.12139620084598582,destabilizing
+EXOSC10,RASA2,0.1010359667008679,destabilizing
+EXOSC10,WIPF2,0.10048128985362881,destabilizing
+EXOSC10,TSHZ2,0.05374163341793192,destabilizing
+EXOSC10,FRMD5,0.06659385734906226,destabilizing
+EXOSC10,LINC00174,0.08804323475236812,destabilizing
+EXOSC10,ARL3,0.07895958587061205,destabilizing
+EXOSC10,MBD5,0.058381389354770795,destabilizing
+EXOSC10,ELAVL3,0.08913666716909766,destabilizing
+EXOSC10,SLIT2,0.10969123156202688,destabilizing
+EXOSC10,UNC5C,0.07791732781047336,destabilizing
+EXOSC10,NEGR1,0.10214531283945359,destabilizing
+EXOSC10,ENOX1,0.12342277973917956,destabilizing
+EXOSC10,TOMM22,0.10923642571017701,destabilizing
+EXOSC10,LSAMP,0.0596971906247626,destabilizing
+EXOSC10,TMED2,0.06893588422308797,destabilizing
+EXOSC10,GRIK2,0.0883888462372239,destabilizing
+EXOSC10,LRRC37A3,0.11324766125031448,destabilizing
+EXOSC10,EYS,0.05684813491233301,destabilizing
+EXOSC10,ARID1B,0.06025522949187445,destabilizing
+EXOSC10,MLLT3,0.13149936316490043,destabilizing
+EXOSC10,ADGRB3,0.059088208505519234,destabilizing
+EXOSC10,SYPL1,0.06096205620523562,destabilizing
+EXOSC10,PTPRD,0.07484424661211352,destabilizing
+EXOSC10,LARP1B,0.07775229545821198,destabilizing
+CNOT1,MPHOSPH8,0.06777634788019038,destabilizing
+CNOT1,SYN3,0.06438756997868221,destabilizing
+CNOT6,CDK12,0.09123473763800914,destabilizing
+CNOT6,CENPP,0.11952562945491367,destabilizing
+CNOT6,ALK,0.11871647943158427,destabilizing
+CNOT6,MLLT3,0.0886811752917034,destabilizing
+CNOT7,TRERF1,0.09229437301512934,destabilizing
+CNOT7,SORCS1,0.07421813808004266,destabilizing
+CNOT7,PDE3A,0.09742082819456913,destabilizing
+CNOT7,UNC79,0.09868906361587686,destabilizing
+CNOT7,DOC2B,0.07518217684665617,destabilizing
+CNOT7,CHD1,0.05528133658261201,destabilizing
+CNOT7,MTMR7,0.11856157908650408,destabilizing
+CNOT7,EPB41L4B,0.06210665480544262,destabilizing
+CNOT7,LRRTM4,0.06729088271245182,destabilizing
+CNOT7,FRY,0.10303524882440653,destabilizing
+CNOT7,MACROD2,0.08947596785333782,destabilizing
+CNOT7,CDK12,0.11769320536653645,destabilizing
+CNOT7,MPHOSPH8,0.06742348327113,destabilizing
+CNOT7,UBR3,0.0670879822985364,destabilizing
+CNOT7,CHST12,0.11949062531973849,destabilizing
+CNOT7,EML5,0.09421101010130567,destabilizing
+CNOT7,PSME4,0.0893377482016656,destabilizing
+CNOT7,TMEM106B,0.09528260327007274,destabilizing
+CNOT7,KCNB2,0.09649822806016785,destabilizing
+CNOT7,ZNF521,0.08373649701275282,destabilizing
+CNOT7,GPR158,0.08485178974089308,destabilizing
+CNOT7,NCOA2,0.06857481888596662,destabilizing
+CNOT7,IFT172,0.07457029907067378,destabilizing
+CNOT7,SIK3,0.07938469960630348,destabilizing
+CNOT7,XKR6,0.07953219130947727,destabilizing
+CNOT7,TCF20,0.09745194042581742,destabilizing
+CNOT7,DGKI,0.06400853985870326,destabilizing
+CNOT7,EXOC6B,0.11751557293369061,destabilizing
+CNOT7,MAGI3,0.08168350552242061,destabilizing
+CNOT7,INPP4B,0.07896491288436014,destabilizing
+CNOT7,SPDYE3,0.07286098702690968,destabilizing
+CNOT7,DMD,0.13155721648088547,destabilizing
+CNOT7,MCU,0.07453359746161492,destabilizing
+CNOT7,SSH2,0.06300470578348352,destabilizing
+CNOT7,DOCK3,0.07693205666804465,destabilizing
+CNOT7,STAG1,0.07415435732101919,destabilizing
+CNOT7,UBE2R2,0.07367027400697367,destabilizing
+CNOT7,GTF2IRD1,0.06008699749650217,destabilizing
+CNOT7,FMN2,0.07346762136648986,destabilizing
+CNOT7,RASA2,0.07085987081372393,destabilizing
+CNOT7,FRMD4A,0.0671730355835868,destabilizing
+CNOT7,SEMA6D,0.06871897982281974,destabilizing
+CNOT7,KAZN,0.07449049360708737,destabilizing
+CNOT7,FRMD5,0.06886642569598479,destabilizing
+CNOT7,PPM1E,0.07179868636430509,destabilizing
+CNOT7,ELAVL3,0.0754469565671325,destabilizing
+CNOT7,CLASP1,0.07168722074901361,destabilizing
+CNOT7,UNC5C,0.09239005290157767,destabilizing
+CNOT7,NEGR1,0.0938238736342181,destabilizing
+CNOT7,NAV3,0.08825005995180463,destabilizing
+CNOT7,EBF1,0.06371448045304713,destabilizing
+CNOT7,TOMM22,0.08485441683738185,destabilizing
+CNOT7,AKAP6,0.07417772703451625,destabilizing
+CNOT7,ZBTB20,0.07586293808074879,destabilizing
+CNOT7,GRIK2,0.06137177621009099,destabilizing
+CNOT7,LRRC37A3,0.09617043887977571,destabilizing
+CNOT7,EYS,0.0640472436906127,destabilizing
+CNOT7,MLLT3,0.12053285758881735,destabilizing
+CNOT7,ADGRB3,0.05613202534578918,destabilizing
+CNOT7,ROBO1,0.07127859005476773,destabilizing
+CNOT7,PTPRD,0.08323858507783645,destabilizing
+CNOT7,LARP1B,0.09214866935896775,destabilizing
+PABPC1,TRERF1,0.3955680656122654,destabilizing
+PABPC1,SORCS1,0.29387140029952336,destabilizing
+PABPC1,NCOA1,0.1461473682398446,destabilizing
+PABPC1,COPA,0.19632644036610505,destabilizing
+PABPC1,FCHSD2,0.20353440028543918,destabilizing
+PABPC1,PDE3A,0.4565965006007183,destabilizing
+PABPC1,UNC79,0.4181174796768277,destabilizing
+PABPC1,DOC2B,0.2976365521215278,destabilizing
+PABPC1,TMTC2,0.3721998838600649,destabilizing
+PABPC1,KALRN,0.2886551352467136,destabilizing
+PABPC1,CHD1,0.23341219828443174,destabilizing
+PABPC1,PAK3,0.14615489954771826,destabilizing
+PABPC1,UBE2E2,0.17036353852580013,destabilizing
+PABPC1,PPARD,0.19974540396664198,destabilizing
+PABPC1,TOX,0.1221590910525368,destabilizing
+PABPC1,BRAF,0.12620943539811474,destabilizing
+PABPC1,RYR2,0.31063714222113037,destabilizing
+PABPC1,ZNF609,0.08374141399106236,destabilizing
+PABPC1,MTMR7,0.4053631847464219,destabilizing
+PABPC1,EIF4E,0.28245573488060666,destabilizing
+PABPC1,SOX11,0.15606218536386476,destabilizing
+PABPC1,EPB41L4B,0.31089338772418185,destabilizing
+PABPC1,CACNA1B,0.27825100031780703,destabilizing
+PABPC1,TBC1D5,0.17022971095497436,destabilizing
+PABPC1,LRRTM4,0.3112519460451876,destabilizing
+PABPC1,SIRPA,0.3449296809800614,destabilizing
+PABPC1,MAP4K3,0.10484002502188171,destabilizing
+PABPC1,PTEN,0.28601882229530445,destabilizing
+PABPC1,SPPL3,0.09278722946593476,destabilizing
+PABPC1,FRY,0.38210716169906744,destabilizing
+PABPC1,RUNX1T1,0.06216206422114991,destabilizing
+PABPC1,MACROD2,0.3496487592496082,destabilizing
+PABPC1,FOXN3,0.17152437417528904,destabilizing
+PABPC1,SHANK2,0.4255751336030692,destabilizing
+PABPC1,CDK12,0.4495914631228139,destabilizing
+PABPC1,RFX7,0.39596710872586416,destabilizing
+PABPC1,UBR5,0.23369618463416528,destabilizing
+PABPC1,JARID2,0.22458543633402062,destabilizing
+PABPC1,MPHOSPH8,0.277628338080065,destabilizing
+PABPC1,RGS7,-0.05526014648372726,stabilizing
+PABPC1,DIP2C,0.28695008341077854,destabilizing
+PABPC1,ZNF423,0.18416439048373545,destabilizing
+PABPC1,UBR3,0.281783579558139,destabilizing
+PABPC1,MGAT5,0.23287505154930604,destabilizing
+PABPC1,DLG2,0.27134792100413296,destabilizing
+PABPC1,CHST12,0.5531183652939841,destabilizing
+PABPC1,EML5,0.4241405757705863,destabilizing
+PABPC1,CENPP,0.19432852505623152,destabilizing
+PABPC1,PSME4,0.3730261034329627,destabilizing
+PABPC1,TMEM106B,0.4205865897907963,destabilizing
+PABPC1,RABGAP1L,0.08728787218749019,destabilizing
+PABPC1,EPHA5,0.3310773573484242,destabilizing
+PABPC1,KCNB2,0.3257737738636013,destabilizing
+PABPC1,ZNF83,0.2352931466583552,destabilizing
+PABPC1,SOX6,0.1877672014435156,destabilizing
+PABPC1,ZNF521,0.3326097340638021,destabilizing
+PABPC1,PLEKHA5,0.24365210395971829,destabilizing
+PABPC1,DTL,0.3264129923754314,destabilizing
+PABPC1,NOVA1,0.4080042961542567,destabilizing
+PABPC1,CCNY,0.3390143032608832,destabilizing
+PABPC1,ARIH1,0.2882075079750265,destabilizing
+PABPC1,FAM171B,0.12378650102705586,destabilizing
+PABPC1,EPB41L5,0.3001091358244028,destabilizing
+PABPC1,GPR158,0.401927364039665,destabilizing
+PABPC1,NCOA2,0.32475661624943986,destabilizing
+PABPC1,PRKCB,0.12460760785721921,destabilizing
+PABPC1,PUM2,0.09887765345844592,destabilizing
+PABPC1,ALK,0.19708027171116596,destabilizing
+PABPC1,ACACA,0.20650719871901566,destabilizing
+PABPC1,ARHGAP26,0.1284462276829377,destabilizing
+PABPC1,CTNND2,0.20740867063871832,destabilizing
+PABPC1,IFT172,0.352347741660851,destabilizing
+PABPC1,CCNT1,0.22454780949497452,destabilizing
+PABPC1,ENAH,0.10779817104900365,destabilizing
+PABPC1,DTWD2,0.3408652709061221,destabilizing
+PABPC1,SIK3,0.2255722356720304,destabilizing
+PABPC1,CPEB3,0.3821844223691017,destabilizing
+PABPC1,CADM2,0.1709113354385639,destabilizing
+PABPC1,XKR6,0.3950554081672132,destabilizing
+PABPC1,RMND5A,0.1601698023074305,destabilizing
+PABPC1,CADPS,0.207779201634395,destabilizing
+PABPC1,FGF13,0.13984625072344867,destabilizing
+PABPC1,TCF20,0.4265311602815965,destabilizing
+PABPC1,CDKAL1,0.18761588379738497,destabilizing
+PABPC1,DGKI,0.27690591848326185,destabilizing
+PABPC1,EXOC6B,0.43846187745778925,destabilizing
+PABPC1,MAGI3,0.33686024056473707,destabilizing
+PABPC1,SBF2,0.21857230426471647,destabilizing
+PABPC1,INPP4B,0.3777296758730141,destabilizing
+PABPC1,ERC1,0.20253812074607985,destabilizing
+PABPC1,PTPRS,0.39486148786428465,destabilizing
+PABPC1,CBFA2T2,0.238568471302721,destabilizing
+PABPC1,SPDYE3,0.33459831844739074,destabilizing
+PABPC1,TMEM178B,0.17881729068939156,destabilizing
+PABPC1,KMT2C,0.12822592016082152,destabilizing
+PABPC1,CACNA2D1,0.13706785691292614,destabilizing
+PABPC1,DMD,0.5257825372201612,destabilizing
+PABPC1,EIF4G3,0.11847510531212532,destabilizing
+PABPC1,MCU,0.334808868103425,destabilizing
+PABPC1,SSH2,0.29224589268138285,destabilizing
+PABPC1,TCF12,0.12250463957931372,destabilizing
+PABPC1,DOCK3,0.39566039668501396,destabilizing
+PABPC1,HS6ST3,0.42057542341696813,destabilizing
+PABPC1,LPP,0.47098576668402425,destabilizing
+PABPC1,STAG1,0.27499176471828596,destabilizing
+PABPC1,CAPZA2,0.3019166105700917,destabilizing
+PABPC1,ADGRL3,0.19804538083184528,destabilizing
+PABPC1,PHACTR1,0.13580750916845022,destabilizing
+PABPC1,UBE2R2,0.3490789000081234,destabilizing
+PABPC1,GTF2IRD1,0.33433767003991793,destabilizing
+PABPC1,CCBE1,0.25637366408743584,destabilizing
+PABPC1,FTX,0.14353163422184445,destabilizing
+PABPC1,VAPA,0.07823990163514062,destabilizing
+PABPC1,JMJD1C,0.09180919945827373,destabilizing
+PABPC1,TTC28,0.22734065101533396,destabilizing
+PABPC1,SBNO1,0.22024619519240368,destabilizing
+PABPC1,RIMS2,0.20574652458674741,destabilizing
+PABPC1,IGF1R,0.18428165152768888,destabilizing
+PABPC1,TRIO,0.23785468473838556,destabilizing
+PABPC1,KCND2,0.1570451350188814,destabilizing
+PABPC1,BTBD9,0.3792483034478888,destabilizing
+PABPC1,CNGB1,0.44953930485613414,destabilizing
+PABPC1,FMN2,0.3205132468092226,destabilizing
+PABPC1,ENSG00000228222,0.5134514503491509,destabilizing
+PABPC1,ATXN1,0.17232583465895307,destabilizing
+PABPC1,PRKN,0.507001909993565,destabilizing
+PABPC1,RASA2,0.3248188499466417,destabilizing
+PABPC1,PPP1R12B,0.3004905609747712,destabilizing
+PABPC1,FRMD4A,0.3079760243402472,destabilizing
+PABPC1,CAMK1D,0.17494791641343607,destabilizing
+PABPC1,PARD3,0.17436304221593715,destabilizing
+PABPC1,SEMA6D,0.30571816778148686,destabilizing
+PABPC1,WIPF2,0.3149656730529334,destabilizing
+PABPC1,WWOX,0.06870987829074231,destabilizing
+PABPC1,DLEU1,0.4926052105928666,destabilizing
+PABPC1,TSHZ2,0.19248595554444384,destabilizing
+PABPC1,MED13L,0.23172385118682093,destabilizing
+PABPC1,AFF3,0.12427259248109628,destabilizing
+PABPC1,KAZN,0.2936723943475201,destabilizing
+PABPC1,KANSL1,0.23082985602919254,destabilizing
+PABPC1,FRMD5,0.3001426077337771,destabilizing
+PABPC1,LINC00174,0.315136607491857,destabilizing
+PABPC1,PPM1E,0.32008820480078853,destabilizing
+PABPC1,ARL3,0.17636627696267937,destabilizing
+PABPC1,MBD5,0.27227938919108746,destabilizing
+PABPC1,ELAVL3,0.2928009911137569,destabilizing
+PABPC1,SLIT2,0.4750020046494498,destabilizing
+PABPC1,SLC8A1,0.14407401596909852,destabilizing
+PABPC1,CLASP1,0.22475660757397065,destabilizing
+PABPC1,DOCK4,0.1587479307495393,destabilizing
+PABPC1,UNC5C,0.3272580629443984,destabilizing
+PABPC1,CACNA2D3,-0.13886441709065594,stabilizing
+PABPC1,RC3H1,0.2577500292255208,destabilizing
+PABPC1,NEGR1,0.2872656573199521,destabilizing
+PABPC1,ENOX1,0.4955792309665591,destabilizing
+PABPC1,SCUBE1,0.2312718006825758,destabilizing
+PABPC1,GPHN,0.2995315878241422,destabilizing
+PABPC1,NAV3,0.39626797954867315,destabilizing
+PABPC1,EBF1,0.1470406097366357,destabilizing
+PABPC1,TOMM22,0.41596893581153405,destabilizing
+PABPC1,MBNL2,0.16648904732766068,destabilizing
+PABPC1,ANKFN1,0.11697136039900188,destabilizing
+PABPC1,MAGI2,0.19055336334489567,destabilizing
+PABPC1,LSAMP,0.23208757503287916,destabilizing
+PABPC1,AKAP6,0.3579195935563021,destabilizing
+PABPC1,TMED2,0.2468032177232924,destabilizing
+PABPC1,ZBTB20,0.3391847143033223,destabilizing
+PABPC1,GRIK2,0.32674959647203006,destabilizing
+PABPC1,MAML3,0.06986221003853467,destabilizing
+PABPC1,SOX5,0.24781826252549288,destabilizing
+PABPC1,LRRC37A3,0.42882160229668886,destabilizing
+PABPC1,TMEM132C,0.11328541198883772,destabilizing
+PABPC1,EYS,0.2645179788629474,destabilizing
+PABPC1,ARID1B,0.26015307902964396,destabilizing
+PABPC1,PRKCE,0.27272753245343606,destabilizing
+PABPC1,RBFOX1,-0.14263612624535355,stabilizing
+PABPC1,SDK1,0.2245364910490745,destabilizing
+PABPC1,NRG1,0.14978052434274053,destabilizing
+PABPC1,MLLT3,0.43634686214793394,destabilizing
+PABPC1,AUTS2,0.12538474201765976,destabilizing
+PABPC1,FMN1,0.19830279456793926,destabilizing
+PABPC1,ADGRB3,0.2411213298242933,destabilizing
+PABPC1,ROBO1,0.3675557627505698,destabilizing
+PABPC1,SYPL1,0.191198751253646,destabilizing
+PABPC1,PTPRD,0.28536167435754284,destabilizing
+PABPC1,FAM155A,0.3656263529321011,destabilizing
+PABPC1,LARP1B,0.4016699283423332,destabilizing
+MSI2,EML5,0.07792271824638337,destabilizing
+MSI2,TMEM106B,0.08448789189618114,destabilizing
+MSI2,DOCK3,0.07710905672905617,destabilizing
+AGO2,MACROD2,0.07383097729747137,destabilizing
+AGO2,AKAP6,0.0701198019958314,destabilizing
+DROSHA,CAPZA2,0.06926394100311582,destabilizing
+DROSHA,LRRC37A3,0.07656145897525118,destabilizing
+DROSHA,MLLT3,0.08218006590043028,destabilizing
+DICER1,TRERF1,0.09533972121719055,destabilizing
+DICER1,PDE3A,0.09776811681062099,destabilizing
+DICER1,DOC2B,0.062046309411872495,destabilizing
+DICER1,FRY,0.09043211489320609,destabilizing
+DICER1,MACROD2,0.07619727900841314,destabilizing
+DICER1,SHANK2,0.10394147106179111,destabilizing
+DICER1,CENPP,0.12951141676351466,destabilizing
+DICER1,TMEM106B,0.09148577616466323,destabilizing
+DICER1,KCNB2,0.09575576879572122,destabilizing
+DICER1,SOX6,0.06443734127839233,destabilizing
+DICER1,GPR158,0.09793553846109007,destabilizing
+DICER1,XKR6,0.08109456935385174,destabilizing
+DICER1,DMD,0.08982520582609309,destabilizing
+DICER1,MCU,0.06386812888825945,destabilizing
+DICER1,WIPF2,0.07320870195476283,destabilizing
+DICER1,FRMD5,0.06310484805676554,destabilizing
+DICER1,SLIT2,0.09160210944721406,destabilizing
+DICER1,UNC5C,0.07636302644816845,destabilizing
+DICER1,NEGR1,0.08907395374887535,destabilizing
+DICER1,GPHN,0.060703761182049384,destabilizing
+DICER1,GRIK2,0.060304237267544046,destabilizing
+DICER1,PRKCE,0.0678639419214086,destabilizing
+DICER1,MLLT3,0.08572083439439002,destabilizing
+ADAR,UNC79,0.09405778315889506,destabilizing
+ADAR,TMTC2,0.07658654465834071,destabilizing
+ADAR,RYR2,0.12315139064100437,destabilizing
+ADAR,LRRTM4,0.07329355878035,destabilizing
+ADAR,MACROD2,0.09035771908216914,destabilizing
+ADAR,SHANK2,0.1204830624077783,destabilizing
+ADAR,CDK12,0.09208322310879025,destabilizing
+ADAR,CHST12,0.11850456649843177,destabilizing
+ADAR,EML5,0.09644481900474572,destabilizing
+ADAR,CENPP,0.12284917227696683,destabilizing
+ADAR,PSME4,0.07041077623025084,destabilizing
+ADAR,ZNF521,0.07763215228234915,destabilizing
+ADAR,NCOA2,0.06435709363415029,destabilizing
+ADAR,CPEB3,0.1067283812034857,destabilizing
+ADAR,EXOC6B,0.08806180917242253,destabilizing
+ADAR,DMD,0.0893945487133388,destabilizing
+ADAR,MCU,0.07158979660034108,destabilizing
+ADAR,DOCK3,0.08150275092262299,destabilizing
+ADAR,HS6ST3,0.08711443891865318,destabilizing
+ADAR,LPP,0.09081741151188197,destabilizing
+ADAR,PRKN,0.0971037125961079,destabilizing
+ADAR,RASA2,0.06859990221925678,destabilizing
+ADAR,FRMD5,0.07302354588239465,destabilizing
+ADAR,LINC00174,0.062165073024674604,destabilizing
+ADAR,SLIT2,0.0926070311801646,destabilizing
+ADAR,UNC5C,0.06872924523492148,destabilizing
+ADAR,GPHN,0.06250681497982045,destabilizing
+ADAR,LRRC37A3,0.0832403380042452,destabilizing
+ADAR,MLLT3,0.09765332139006924,destabilizing
+ADARB1,EML5,0.07803984275201618,destabilizing
+CPSF1,CENPP,0.11939918159956894,destabilizing
+CPSF1,MAGI3,0.06909528408511137,destabilizing
+CPSF1,DMD,0.08031270503789628,destabilizing
+CPSF1,SYPL1,0.05328884877105955,destabilizing
+CPSF3,TRERF1,0.08677338109456922,destabilizing
+CPSF3,UNC79,0.09301502066668774,destabilizing
+CPSF3,KALRN,0.06854004428469905,destabilizing
+CPSF3,FRY,0.08322175365046633,destabilizing
+CPSF3,MPHOSPH8,0.07656508140372857,destabilizing
+CPSF3,KCNB2,0.09529605514715818,destabilizing
+CPSF3,PLEKHA5,0.06289674747663701,destabilizing
+CPSF3,NOVA1,0.13456980921501913,destabilizing
+CPSF3,ALK,0.10798195002584186,destabilizing
+CPSF3,DTWD2,0.13733345176540804,destabilizing
+CPSF3,XKR6,0.07393583403567962,destabilizing
+CPSF3,DGKI,0.06875507106367185,destabilizing
+CPSF3,EXOC6B,0.10098118969904267,destabilizing
+CPSF3,MAGI3,0.08143880455376426,destabilizing
+CPSF3,SSH2,0.06491134025284642,destabilizing
+CPSF3,STAG1,0.06554081267305677,destabilizing
+CPSF3,CAPZA2,0.08153887203311215,destabilizing
+CPSF3,ENSG00000228222,0.12401788039671145,destabilizing
+CPSF3,RASA2,0.07635473782411026,destabilizing
+CPSF3,SEMA6D,0.06655344530561118,destabilizing
+CPSF3,WIPF2,0.08271168869296062,destabilizing
+CPSF3,LINC00174,0.08435413594958821,destabilizing
+CPSF3,LRRC37A3,0.07578966646035216,destabilizing
+CPSF3,MLLT3,0.09475626351910157,destabilizing
+CSTF1,EIF4E,0.1392876845144812,destabilizing
+CSTF1,FRY,0.08690745149358914,destabilizing
+CSTF1,MACROD2,0.0689151124164659,destabilizing
+CSTF1,CDK12,0.09414321897782085,destabilizing
+CSTF1,ALK,0.1066687093747488,destabilizing
+CSTF1,CCNT1,0.06375121207175567,destabilizing
+CSTF1,XKR6,0.08524888484765018,destabilizing
+CSTF1,MAGI3,0.07523839841918101,destabilizing
+CSTF1,DMD,0.08540002486391117,destabilizing
+CSTF1,DOCK3,0.09959388982232636,destabilizing
+CSTF1,BTBD9,0.08000942282487589,destabilizing
+CSTF1,DLEU1,0.11075234451024324,destabilizing
+CSTF1,FRMD5,0.06252567496626901,destabilizing
+CSTF1,LINC00174,0.06298617328682833,destabilizing
+CSTF1,MBD5,0.06089093197896074,destabilizing
+CSTF1,AKAP6,0.06438185374044772,destabilizing
+CSTF1,ZBTB20,0.0792532203566666,destabilizing
+CSTF1,GRIK2,0.05897136427966865,destabilizing
+CSTF1,LRRC37A3,0.08067512286250098,destabilizing
+CSTF1,EYS,0.05498629241797912,destabilizing
+CSTF1,MLLT3,0.0836236798944941,destabilizing
+CSTF3,TRERF1,0.08970270257390375,destabilizing
+CSTF3,SORCS1,0.07206764819524628,destabilizing
+CSTF3,PDE3A,0.10613005069292555,destabilizing
+CSTF3,UNC79,0.08132843110204593,destabilizing
+CSTF3,DOC2B,0.07491237007774376,destabilizing
+CSTF3,TMTC2,0.11046401674538577,destabilizing
+CSTF3,KALRN,0.06082561915319397,destabilizing
+CSTF3,RYR2,0.10948349610185282,destabilizing
+CSTF3,MTMR7,0.14134318183439407,destabilizing
+CSTF3,EIF4E,0.12323707465145753,destabilizing
+CSTF3,LRRTM4,0.06964123171836413,destabilizing
+CSTF3,FRY,0.130891345499871,destabilizing
+CSTF3,MACROD2,0.09919251449325898,destabilizing
+CSTF3,SHANK2,0.11645232888120989,destabilizing
+CSTF3,CDK12,0.15205597223675194,destabilizing
+CSTF3,RFX7,0.11793428845910733,destabilizing
+CSTF3,MPHOSPH8,0.10852201887716648,destabilizing
+CSTF3,DLG2,0.0697528188964683,destabilizing
+CSTF3,CHST12,0.1534197247422882,destabilizing
+CSTF3,EML5,0.09806780807083369,destabilizing
+CSTF3,CENPP,0.18599637380469647,destabilizing
+CSTF3,PSME4,0.090126589976577,destabilizing
+CSTF3,TMEM106B,0.10599157586140145,destabilizing
+CSTF3,EPHA5,0.07624627215211534,destabilizing
+CSTF3,KCNB2,0.14791842989744816,destabilizing
+CSTF3,ZNF83,0.0734934861848259,destabilizing
+CSTF3,SOX6,0.06513879328658079,destabilizing
+CSTF3,ZNF521,0.10498437647432586,destabilizing
+CSTF3,NOVA1,0.12215000430317534,destabilizing
+CSTF3,CCNY,0.10691433380191086,destabilizing
+CSTF3,ARIH1,0.0788519985324413,destabilizing
+CSTF3,GPR158,0.10440862018239484,destabilizing
+CSTF3,ALK,0.17498227712970638,destabilizing
+CSTF3,IFT172,0.10860732604604466,destabilizing
+CSTF3,CCNT1,0.06904488202077412,destabilizing
+CSTF3,DTWD2,0.20029344229561633,destabilizing
+CSTF3,SIK3,0.09574558680007131,destabilizing
+CSTF3,CPEB3,0.10448141218540677,destabilizing
+CSTF3,XKR6,0.129585793797347,destabilizing
+CSTF3,DGKI,0.08552159277314199,destabilizing
+CSTF3,EXOC6B,0.13242407946681262,destabilizing
+CSTF3,MAGI3,0.1141977307827863,destabilizing
+CSTF3,SBF2,0.056048342821349566,destabilizing
+CSTF3,INPP4B,0.09305337322008025,destabilizing
+CSTF3,PTPRS,0.11928805252907847,destabilizing
+CSTF3,DMD,0.15532626298309132,destabilizing
+CSTF3,MCU,0.09325152979436224,destabilizing
+CSTF3,SSH2,0.0795391280450225,destabilizing
+CSTF3,DOCK3,0.1285558327863848,destabilizing
+CSTF3,HS6ST3,0.10259603605572079,destabilizing
+CSTF3,STAG1,0.06711144353254644,destabilizing
+CSTF3,CAPZA2,0.08598966764281073,destabilizing
+CSTF3,ADGRL3,0.0725774752915609,destabilizing
+CSTF3,PHACTR1,0.07611302059703265,destabilizing
+CSTF3,UBE2R2,0.08735536601898108,destabilizing
+CSTF3,GTF2IRD1,0.06381307158691896,destabilizing
+CSTF3,RIMS2,0.08035752177456103,destabilizing
+CSTF3,BTBD9,0.07861620014847859,destabilizing
+CSTF3,FMN2,0.06892766491571661,destabilizing
+CSTF3,ENSG00000228222,0.2071475420779967,destabilizing
+CSTF3,PRKN,0.13779689063968092,destabilizing
+CSTF3,RASA2,0.10143719916287641,destabilizing
+CSTF3,PPP1R12B,0.08264972914214275,destabilizing
+CSTF3,SEMA6D,0.06337630069247767,destabilizing
+CSTF3,WIPF2,0.09694700234144842,destabilizing
+CSTF3,DLEU1,0.11266235483628102,destabilizing
+CSTF3,KAZN,0.10741705966883214,destabilizing
+CSTF3,FRMD5,0.08139831278875943,destabilizing
+CSTF3,LINC00174,0.08998871468057885,destabilizing
+CSTF3,ARL3,0.07096665617737256,destabilizing
+CSTF3,ELAVL3,0.08116481646667331,destabilizing
+CSTF3,SLIT2,0.12931857404062,destabilizing
+CSTF3,CLASP1,0.0747118360739149,destabilizing
+CSTF3,UNC5C,0.09009452485024413,destabilizing
+CSTF3,NEGR1,0.11830500994675369,destabilizing
+CSTF3,ENOX1,0.1252694974459903,destabilizing
+CSTF3,GPHN,0.0760443790452211,destabilizing
+CSTF3,NAV3,0.10086460988771571,destabilizing
+CSTF3,TOMM22,0.09673791372539217,destabilizing
+CSTF3,AKAP6,0.08601959883788866,destabilizing
+CSTF3,ZBTB20,0.10649264362609,destabilizing
+CSTF3,GRIK2,0.06974164082578535,destabilizing
+CSTF3,LRRC37A3,0.11808763828253964,destabilizing
+CSTF3,EYS,0.06631531975944119,destabilizing
+CSTF3,MLLT3,0.15453739923111887,destabilizing
+CSTF3,ADGRB3,0.06223944612566768,destabilizing
+CSTF3,ROBO1,0.06747602894714834,destabilizing
+CSTF3,PTPRD,0.06304747506639108,destabilizing
+CSTF3,FAM155A,0.10801306610682215,destabilizing
+CSTF3,LARP1B,0.07964617596408093,destabilizing
+NUDT21,TRERF1,0.09604560011371044,destabilizing
+NUDT21,UNC79,0.08444036239060947,destabilizing
+NUDT21,DOC2B,0.07204467969210519,destabilizing
+NUDT21,TMTC2,0.1037290369141482,destabilizing
+NUDT21,KALRN,0.06356856573199128,destabilizing
+NUDT21,CHD1,0.05618828861368109,destabilizing
+NUDT21,RYR2,0.11215337782788162,destabilizing
+NUDT21,MTMR7,0.08289897872387038,destabilizing
+NUDT21,LRRTM4,0.06224627543875867,destabilizing
+NUDT21,PTEN,0.08600901938846618,destabilizing
+NUDT21,FRY,0.10803606765588553,destabilizing
+NUDT21,MACROD2,0.11161151170604104,destabilizing
+NUDT21,SHANK2,0.11762052496986217,destabilizing
+NUDT21,CDK12,0.13746536644552187,destabilizing
+NUDT21,MPHOSPH8,0.07572978922175036,destabilizing
+NUDT21,DLG2,0.08207639296118217,destabilizing
+NUDT21,CHST12,0.17624764974892446,destabilizing
+NUDT21,EML5,0.08965210638045278,destabilizing
+NUDT21,CENPP,0.12816123886701833,destabilizing
+NUDT21,TMEM106B,0.0722237241971343,destabilizing
+NUDT21,KCNB2,0.12000461561396276,destabilizing
+NUDT21,ZNF83,0.07815834045469239,destabilizing
+NUDT21,SOX6,0.05799733788872231,destabilizing
+NUDT21,PLEKHA5,0.06358900606860657,destabilizing
+NUDT21,CCNY,0.08811201299353086,destabilizing
+NUDT21,ARIH1,0.06446499889555524,destabilizing
+NUDT21,GPR158,0.09310480385234492,destabilizing
+NUDT21,ALK,0.15605988531621323,destabilizing
+NUDT21,IFT172,0.08753158562137882,destabilizing
+NUDT21,CCNT1,0.06664809982925428,destabilizing
+NUDT21,DTWD2,0.14027988984611794,destabilizing
+NUDT21,SIK3,0.07846826135078014,destabilizing
+NUDT21,XKR6,0.11560972818116534,destabilizing
+NUDT21,CADPS,0.07317172559815484,destabilizing
+NUDT21,TCF20,0.08681697643147533,destabilizing
+NUDT21,DGKI,0.06569645370024596,destabilizing
+NUDT21,EXOC6B,0.11291023011566637,destabilizing
+NUDT21,MAGI3,0.08391722768401133,destabilizing
+NUDT21,INPP4B,0.06887388073286974,destabilizing
+NUDT21,DMD,0.12442733984845361,destabilizing
+NUDT21,MCU,0.09087515680802546,destabilizing
+NUDT21,SSH2,0.07324601321007007,destabilizing
+NUDT21,DOCK3,0.1110166529128997,destabilizing
+NUDT21,CAPZA2,0.09210925603266339,destabilizing
+NUDT21,PHACTR1,0.06152546292766861,destabilizing
+NUDT21,UBE2R2,0.08035760484949908,destabilizing
+NUDT21,TTC28,0.08455708972778497,destabilizing
+NUDT21,FMN2,0.06306736907523405,destabilizing
+NUDT21,ENSG00000228222,0.12199087093362754,destabilizing
+NUDT21,RASA2,0.07802873031594024,destabilizing
+NUDT21,FRMD4A,0.054663060930955604,destabilizing
+NUDT21,SEMA6D,0.06896299575013663,destabilizing
+NUDT21,WIPF2,0.09319621516307972,destabilizing
+NUDT21,TSHZ2,0.06923003819292377,destabilizing
+NUDT21,KANSL1,0.06688057659098873,destabilizing
+NUDT21,FRMD5,0.08431306556841828,destabilizing
+NUDT21,MBD5,0.07952909639543311,destabilizing
+NUDT21,CLASP1,0.0808641738692469,destabilizing
+NUDT21,UNC5C,0.09604109755799453,destabilizing
+NUDT21,NAV3,0.07850366579556563,destabilizing
+NUDT21,TOMM22,0.0813279020093849,destabilizing
+NUDT21,AKAP6,0.08170739622027884,destabilizing
+NUDT21,ZBTB20,0.09588888787309495,destabilizing
+NUDT21,GRIK2,0.05996461693734474,destabilizing
+NUDT21,LRRC37A3,0.09146938641082333,destabilizing
+NUDT21,MLLT3,0.12252399581146103,destabilizing
+NUDT21,SYPL1,0.06167992311106333,destabilizing
+NUDT21,PTPRD,0.06751111308900302,destabilizing
+NUDT21,FAM155A,0.09844847369926357,destabilizing
+NUDT21,LARP1B,0.07289414794769329,destabilizing
+METTL3,SSH2,0.06513036841591055,destabilizing
+METTL3,CAPZA2,0.08458750005911704,destabilizing
+METTL3,GRIK2,0.05776824792958682,destabilizing
+METTL3,MLLT3,0.10018821371468753,destabilizing
+YTHDF1,PPARD,0.061897992386974895,destabilizing
+YTHDF1,EIF4E,0.13079819808966667,destabilizing
+YTHDF1,SHANK2,0.11490106424439782,destabilizing
+YTHDF1,CDK12,0.13646304890922292,destabilizing
+YTHDF1,CHST12,0.12289718421098637,destabilizing
+YTHDF1,CENPP,0.1178065532658791,destabilizing
+YTHDF1,PSME4,0.09805773503582678,destabilizing
+YTHDF1,NOVA1,0.10476755180145038,destabilizing
+YTHDF1,CPEB3,0.09506316822917107,destabilizing
+YTHDF1,XKR6,0.07129452949257604,destabilizing
+YTHDF1,MAGI3,0.07300178141570624,destabilizing
+YTHDF1,DMD,0.0973541620747929,destabilizing
+YTHDF1,MCU,0.07776774428207378,destabilizing
+YTHDF1,DOCK3,0.10928936735842795,destabilizing
+YTHDF1,GTF2IRD1,0.06054901868232777,destabilizing
+YTHDF1,CNGB1,0.08475013221300833,destabilizing
+YTHDF1,ENSG00000228222,0.12687148195133294,destabilizing
+YTHDF1,WIPF2,0.08082184386107691,destabilizing
+YTHDF1,KAZN,0.07046243394754333,destabilizing
+YTHDF1,SLIT2,0.09939540719399106,destabilizing
+YTHDF1,UNC5C,0.07742261947170086,destabilizing
+YTHDF1,ENOX1,0.11577947242134903,destabilizing
+YTHDF1,TOMM22,0.08488366755489243,destabilizing
+YTHDF1,AKAP6,0.0682190155318359,destabilizing
+YTHDF1,ZBTB20,0.07472381313704274,destabilizing
+YTHDF1,MLLT3,0.09762466623320186,destabilizing
+YTHDF1,ROBO1,0.06928390146057986,destabilizing
+YTHDF2,TRERF1,0.12586067751864882,destabilizing
+YTHDF2,SORCS1,0.10073515364228645,destabilizing
+YTHDF2,NCOA1,0.0596901727240283,destabilizing
+YTHDF2,COPA,0.06862565180162684,destabilizing
+YTHDF2,FCHSD2,0.09395363668953424,destabilizing
+YTHDF2,PDE3A,0.1594879890206339,destabilizing
+YTHDF2,UNC79,0.18862308933915908,destabilizing
+YTHDF2,DOC2B,0.1032240323520078,destabilizing
+YTHDF2,TMTC2,0.1557274428375522,destabilizing
+YTHDF2,KALRN,0.10123357362936684,destabilizing
+YTHDF2,CHD1,0.09589283562844989,destabilizing
+YTHDF2,PPARD,0.07880739043189677,destabilizing
+YTHDF2,MTMR7,0.14584935659877682,destabilizing
+YTHDF2,EIF4E,0.171893839233281,destabilizing
+YTHDF2,SOX11,0.08240379763043326,destabilizing
+YTHDF2,EPB41L4B,0.11611868938274848,destabilizing
+YTHDF2,CACNA1B,0.10288026788803922,destabilizing
+YTHDF2,LRRTM4,0.10852985446244481,destabilizing
+YTHDF2,SIRPA,0.14686762770628484,destabilizing
+YTHDF2,PTEN,0.09707845670746648,destabilizing
+YTHDF2,FRY,0.11739945366250362,destabilizing
+YTHDF2,MACROD2,0.13588030954490765,destabilizing
+YTHDF2,SHANK2,0.2061759751817783,destabilizing
+YTHDF2,CDK12,0.19674109377355764,destabilizing
+YTHDF2,RFX7,0.16352504360410874,destabilizing
+YTHDF2,UBR5,0.07662031397050738,destabilizing
+YTHDF2,JARID2,0.06942841720062704,destabilizing
+YTHDF2,MPHOSPH8,0.1232447040347016,destabilizing
+YTHDF2,DIP2C,0.1039456995385845,destabilizing
+YTHDF2,UBR3,0.07307022875187787,destabilizing
+YTHDF2,MGAT5,0.056206380499233446,destabilizing
+YTHDF2,DLG2,0.07885130774710739,destabilizing
+YTHDF2,CHST12,0.24144117050238362,destabilizing
+YTHDF2,EML5,0.18772644858211945,destabilizing
+YTHDF2,CENPP,0.11967394372591775,destabilizing
+YTHDF2,PSME4,0.15026752665928497,destabilizing
+YTHDF2,TMEM106B,0.1406834548798432,destabilizing
+YTHDF2,EPHA5,0.12661780495543126,destabilizing
+YTHDF2,KCNB2,0.12207599995389032,destabilizing
+YTHDF2,ZNF83,0.09058491003361811,destabilizing
+YTHDF2,SOX6,0.08827495833299319,destabilizing
+YTHDF2,ZNF521,0.14014326146178657,destabilizing
+YTHDF2,PLEKHA5,0.07374676603480458,destabilizing
+YTHDF2,DTL,0.12589738845343987,destabilizing
+YTHDF2,NOVA1,0.17242323062795198,destabilizing
+YTHDF2,CCNY,0.1482655720219708,destabilizing
+YTHDF2,ARIH1,0.10397452801792909,destabilizing
+YTHDF2,EPB41L5,0.0998445093662409,destabilizing
+YTHDF2,GPR158,0.12114568426991998,destabilizing
+YTHDF2,NCOA2,0.10165669019047208,destabilizing
+YTHDF2,MARCKS,0.06986169157008817,destabilizing
+YTHDF2,ALK,0.10939802686444533,destabilizing
+YTHDF2,ACACA,0.07222141603468951,destabilizing
+YTHDF2,IFT172,0.14562500605341694,destabilizing
+YTHDF2,CCNT1,0.07766248657818758,destabilizing
+YTHDF2,DTWD2,0.1820171061441085,destabilizing
+YTHDF2,SIK3,0.11233891489738312,destabilizing
+YTHDF2,CPEB3,0.1504990428709027,destabilizing
+YTHDF2,CADM2,0.08921394253180924,destabilizing
+YTHDF2,XKR6,0.1537289816517175,destabilizing
+YTHDF2,RMND5A,0.057860757049127555,destabilizing
+YTHDF2,CADPS,0.077370242925226,destabilizing
+YTHDF2,TCF20,0.13818622490511845,destabilizing
+YTHDF2,CDKAL1,0.08307854565839708,destabilizing
+YTHDF2,DGKI,0.09590412658186039,destabilizing
+YTHDF2,EXOC6B,0.1906074456856508,destabilizing
+YTHDF2,MAGI3,0.14812322742078113,destabilizing
+YTHDF2,SBF2,0.07743582643658455,destabilizing
+YTHDF2,INPP4B,0.13055698563867107,destabilizing
+YTHDF2,PTPRS,0.12814599225521633,destabilizing
+YTHDF2,CBFA2T2,0.059569589919934565,destabilizing
+YTHDF2,SPDYE3,0.12492046248751815,destabilizing
+YTHDF2,DMD,0.1800606793862356,destabilizing
+YTHDF2,EIF4G3,0.058939644970549834,destabilizing
+YTHDF2,MCU,0.10977562254848591,destabilizing
+YTHDF2,SSH2,0.10141926859899848,destabilizing
+YTHDF2,DOCK3,0.1598101527783526,destabilizing
+YTHDF2,HS6ST3,0.1463526308218389,destabilizing
+YTHDF2,LPP,0.19851767649801638,destabilizing
+YTHDF2,STAG1,0.12138392780831575,destabilizing
+YTHDF2,CAPZA2,0.12494003115721615,destabilizing
+YTHDF2,ADGRL3,0.07727742278354956,destabilizing
+YTHDF2,UBE2R2,0.16365761889350813,destabilizing
+YTHDF2,GTF2IRD1,0.09889768959039207,destabilizing
+YTHDF2,CCBE1,0.05573509943507484,destabilizing
+YTHDF2,FTX,0.07123466516325955,destabilizing
+YTHDF2,VAPA,0.05524297686719179,destabilizing
+YTHDF2,TTC28,0.08969630606662833,destabilizing
+YTHDF2,SBNO1,0.07647382100759402,destabilizing
+YTHDF2,RIMS2,0.07353984638159397,destabilizing
+YTHDF2,IGF1R,0.06373656035034167,destabilizing
+YTHDF2,TRIO,0.08295084132229705,destabilizing
+YTHDF2,BTBD9,0.1341703102743346,destabilizing
+YTHDF2,CNGB1,0.21269670795106863,destabilizing
+YTHDF2,FMN2,0.11783802631889632,destabilizing
+YTHDF2,ENSG00000228222,0.24064366135920015,destabilizing
+YTHDF2,ATXN1,0.06482645094010142,destabilizing
+YTHDF2,PRKN,0.16262189829601986,destabilizing
+YTHDF2,RASA2,0.1719810443340702,destabilizing
+YTHDF2,PPP1R12B,0.08469681786049005,destabilizing
+YTHDF2,FRMD4A,0.1031432547749087,destabilizing
+YTHDF2,CAMK1D,0.06128199363455393,destabilizing
+YTHDF2,SEMA6D,0.0986741191697419,destabilizing
+YTHDF2,WIPF2,0.15322476702295706,destabilizing
+YTHDF2,DLEU1,0.15971007464888215,destabilizing
+YTHDF2,TSHZ2,0.0720232526812145,destabilizing
+YTHDF2,MED13L,0.08284188206060239,destabilizing
+YTHDF2,AFF3,0.06226561219007716,destabilizing
+YTHDF2,KAZN,0.1163596286662109,destabilizing
+YTHDF2,KANSL1,0.0806488532259573,destabilizing
+YTHDF2,FRMD5,0.11465773294337925,destabilizing
+YTHDF2,LINC00174,0.16796910818721073,destabilizing
+YTHDF2,PPM1E,0.13732550644939528,destabilizing
+YTHDF2,ARL3,0.07290741232359255,destabilizing
+YTHDF2,MBD5,0.12134390793128816,destabilizing
+YTHDF2,ELAVL3,0.14044136153831804,destabilizing
+YTHDF2,SLIT2,0.19228871468548084,destabilizing
+YTHDF2,UNC5C,0.11798820598309813,destabilizing
+YTHDF2,CACNA2D3,-0.07589529528350124,stabilizing
+YTHDF2,RC3H1,0.10125338077083143,destabilizing
+YTHDF2,NEGR1,0.1312700570019238,destabilizing
+YTHDF2,ENOX1,0.2001126293906065,destabilizing
+YTHDF2,SCUBE1,0.09799182131117838,destabilizing
+YTHDF2,GPHN,0.10616805487455637,destabilizing
+YTHDF2,NAV3,0.1815544295642424,destabilizing
+YTHDF2,TOMM22,0.18753021666178313,destabilizing
+YTHDF2,MAGI2,0.08038330832478584,destabilizing
+YTHDF2,LSAMP,0.1265628830666357,destabilizing
+YTHDF2,AKAP6,0.10812242821895589,destabilizing
+YTHDF2,TMED2,0.11645144948273002,destabilizing
+YTHDF2,ZBTB20,0.10138781235480615,destabilizing
+YTHDF2,GRIK2,0.09908205862620138,destabilizing
+YTHDF2,SOX5,0.07360391660229101,destabilizing
+YTHDF2,LRRC37A3,0.1789582809577865,destabilizing
+YTHDF2,TMEM132C,0.0756045375992036,destabilizing
+YTHDF2,EYS,0.08863107436381384,destabilizing
+YTHDF2,ARID1B,0.08992943526210519,destabilizing
+YTHDF2,PRKCE,0.09832385908254257,destabilizing
+YTHDF2,RBFOX1,-0.0810240687594516,stabilizing
+YTHDF2,SDK1,0.07731654770712564,destabilizing
+YTHDF2,MLLT3,0.22646484227421013,destabilizing
+YTHDF2,ADGRB3,0.06422960627832991,destabilizing
+YTHDF2,ROBO1,0.10964517161820146,destabilizing
+YTHDF2,SYPL1,0.057547176469218385,destabilizing
+YTHDF2,PTPRD,0.10967647399245417,destabilizing
+YTHDF2,FAM155A,0.15428803023673773,destabilizing
+YTHDF2,LARP1B,0.14219809753166113,destabilizing
+YTHDF3,MACROD2,0.08283744023547455,destabilizing
+YTHDF3,ALK,0.10331336413139665,destabilizing
+YTHDF3,MLLT3,0.08533085608999112,destabilizing
+YTHDF3,PTPRD,0.056472000406473516,destabilizing
+YTHDF3,LARP1B,0.06174515782870721,destabilizing
+YTHDC1,TRERF1,0.14012589461274472,destabilizing
+YTHDC1,SORCS1,0.09009821449309373,destabilizing
+YTHDC1,FCHSD2,0.07570926852813305,destabilizing
+YTHDC1,PDE3A,0.1406147345401884,destabilizing
+YTHDC1,UNC79,0.13350515339068197,destabilizing
+YTHDC1,DOC2B,0.09900273403036434,destabilizing
+YTHDC1,TMTC2,0.11794504583319872,destabilizing
+YTHDC1,KALRN,0.06672009638382811,destabilizing
+YTHDC1,CHD1,0.07883656688277572,destabilizing
+YTHDC1,PPARD,0.08706886053052289,destabilizing
+YTHDC1,RYR2,0.12064455514614869,destabilizing
+YTHDC1,MTMR7,0.1101691855194088,destabilizing
+YTHDC1,EIF4E,0.1162534810677001,destabilizing
+YTHDC1,EPB41L4B,0.07584045611700073,destabilizing
+YTHDC1,CACNA1B,0.0665758666981746,destabilizing
+YTHDC1,LRRTM4,0.08462648866175791,destabilizing
+YTHDC1,SIRPA,0.11235574082348605,destabilizing
+YTHDC1,FRY,0.14102986434017298,destabilizing
+YTHDC1,MACROD2,0.10763820794301623,destabilizing
+YTHDC1,SHANK2,0.2048672181523087,destabilizing
+YTHDC1,CDK12,0.15349442278628256,destabilizing
+YTHDC1,RFX7,0.13666627184350838,destabilizing
+YTHDC1,UBR5,0.06255330044409049,destabilizing
+YTHDC1,MPHOSPH8,0.06711025692248118,destabilizing
+YTHDC1,DIP2C,0.08708581535554673,destabilizing
+YTHDC1,UBR3,0.09483097352562364,destabilizing
+YTHDC1,DLG2,0.07316673989721241,destabilizing
+YTHDC1,CHST12,0.18763799768372244,destabilizing
+YTHDC1,EML5,0.13092350155899415,destabilizing
+YTHDC1,CENPP,0.13507854265787347,destabilizing
+YTHDC1,PSME4,0.12184471805513893,destabilizing
+YTHDC1,TMEM106B,0.13336435636885083,destabilizing
+YTHDC1,EPHA5,0.08150511826302921,destabilizing
+YTHDC1,KCNB2,0.12361705348970868,destabilizing
+YTHDC1,ZNF83,0.08890874536374349,destabilizing
+YTHDC1,ZNF521,0.10722292801301053,destabilizing
+YTHDC1,DTL,0.09808602114397846,destabilizing
+YTHDC1,NOVA1,0.1336587228870345,destabilizing
+YTHDC1,CCNY,0.1166901927513516,destabilizing
+YTHDC1,ARIH1,0.09591642666176052,destabilizing
+YTHDC1,EPB41L5,0.057579446134010934,destabilizing
+YTHDC1,GPR158,0.12448808966289295,destabilizing
+YTHDC1,NCOA2,0.08425412700187813,destabilizing
+YTHDC1,ALK,0.1135218929862067,destabilizing
+YTHDC1,IFT172,0.07383386697561359,destabilizing
+YTHDC1,CCNT1,0.0943485132368288,destabilizing
+YTHDC1,DTWD2,0.15574417064605095,destabilizing
+YTHDC1,SIK3,0.12104413980309983,destabilizing
+YTHDC1,CPEB3,0.10635270528009289,destabilizing
+YTHDC1,CADM2,0.059105996007136515,destabilizing
+YTHDC1,XKR6,0.14062108173896137,destabilizing
+YTHDC1,CADPS,0.06251172157874187,destabilizing
+YTHDC1,TCF20,0.11459607182837667,destabilizing
+YTHDC1,CDKAL1,0.08102843668609688,destabilizing
+YTHDC1,DGKI,0.10484917450414034,destabilizing
+YTHDC1,EXOC6B,0.17079851408670826,destabilizing
+YTHDC1,MAGI3,0.11833533945223075,destabilizing
+YTHDC1,INPP4B,0.08925619058143089,destabilizing
+YTHDC1,PTPRS,0.16026670212508104,destabilizing
+YTHDC1,SPDYE3,0.0882892882273439,destabilizing
+YTHDC1,TMEM178B,0.06409251713364582,destabilizing
+YTHDC1,DMD,0.1603834329894565,destabilizing
+YTHDC1,MCU,0.1095789705416157,destabilizing
+YTHDC1,SSH2,0.07564105143119293,destabilizing
+YTHDC1,DOCK3,0.14075353100544713,destabilizing
+YTHDC1,HS6ST3,0.1302696453876212,destabilizing
+YTHDC1,LPP,0.11301818223260576,destabilizing
+YTHDC1,STAG1,0.09282127251806323,destabilizing
+YTHDC1,CAPZA2,0.09831267608120642,destabilizing
+YTHDC1,UBE2R2,0.12813210696439897,destabilizing
+YTHDC1,GTF2IRD1,0.08875129438440804,destabilizing
+YTHDC1,CCBE1,0.050814118749841694,destabilizing
+YTHDC1,SBNO1,0.0628219287298265,destabilizing
+YTHDC1,TRIO,0.05927183284068455,destabilizing
+YTHDC1,BTBD9,0.11852087657697788,destabilizing
+YTHDC1,CNGB1,0.12675776453502957,destabilizing
+YTHDC1,FMN2,0.08495932172714091,destabilizing
+YTHDC1,ENSG00000228222,0.1847560691149708,destabilizing
+YTHDC1,PRKN,0.17890165455829665,destabilizing
+YTHDC1,RASA2,0.09584515622048599,destabilizing
+YTHDC1,FRMD4A,0.07857435464848515,destabilizing
+YTHDC1,SEMA6D,0.06668676795758298,destabilizing
+YTHDC1,WIPF2,0.09330159080496261,destabilizing
+YTHDC1,DLEU1,0.13587463549419979,destabilizing
+YTHDC1,KAZN,0.10605986363386258,destabilizing
+YTHDC1,FRMD5,0.1004567760521346,destabilizing
+YTHDC1,LINC00174,0.0628672504858221,destabilizing
+YTHDC1,PPM1E,0.1074193378692963,destabilizing
+YTHDC1,ARL3,0.06986109067796606,destabilizing
+YTHDC1,MBD5,0.06814083141820178,destabilizing
+YTHDC1,ELAVL3,0.10768960814729597,destabilizing
+YTHDC1,SLIT2,0.1548137822520112,destabilizing
+YTHDC1,CLASP1,0.08641840773465267,destabilizing
+YTHDC1,UNC5C,0.10427251643835664,destabilizing
+YTHDC1,NEGR1,0.10039824322308909,destabilizing
+YTHDC1,ENOX1,0.14322876376000213,destabilizing
+YTHDC1,GPHN,0.09604756038692544,destabilizing
+YTHDC1,NAV3,0.1260155245770204,destabilizing
+YTHDC1,TOMM22,0.14970510313647728,destabilizing
+YTHDC1,MAGI2,0.05983696810810649,destabilizing
+YTHDC1,AKAP6,0.07916546845381663,destabilizing
+YTHDC1,ZBTB20,0.0942232247010183,destabilizing
+YTHDC1,GRIK2,0.08596930398791969,destabilizing
+YTHDC1,LRRC37A3,0.1561964711896076,destabilizing
+YTHDC1,EYS,0.06271210612854214,destabilizing
+YTHDC1,ARID1B,0.07088442164255646,destabilizing
+YTHDC1,PRKCE,0.06984461821827107,destabilizing
+YTHDC1,RBFOX1,-0.0737157768750954,stabilizing
+YTHDC1,MLLT3,0.16891756485017745,destabilizing
+YTHDC1,ADGRB3,0.05862757470785122,destabilizing
+YTHDC1,ROBO1,0.10541734054050218,destabilizing
+YTHDC1,PTPRD,0.08508605073247144,destabilizing
+YTHDC1,FAM155A,0.1478318014747646,destabilizing
+YTHDC1,LARP1B,0.12176946149682878,destabilizing
+ALKBH5,TRERF1,0.1439942711315705,destabilizing
+ALKBH5,SORCS1,0.09929649929518407,destabilizing
+ALKBH5,COPA,0.0695166283099589,destabilizing
+ALKBH5,FCHSD2,0.07363945580205503,destabilizing
+ALKBH5,PDE3A,0.16361702600133404,destabilizing
+ALKBH5,UNC79,0.1426408823979769,destabilizing
+ALKBH5,DOC2B,0.11966832062553202,destabilizing
+ALKBH5,TMTC2,0.14347121105425767,destabilizing
+ALKBH5,KALRN,0.10297702628585394,destabilizing
+ALKBH5,CHD1,0.08650254354891893,destabilizing
+ALKBH5,PPARD,0.07405425382990878,destabilizing
+ALKBH5,TOX,0.0782882146039525,destabilizing
+ALKBH5,RYR2,0.12237056234967826,destabilizing
+ALKBH5,MTMR7,0.1690512615696744,destabilizing
+ALKBH5,EIF4E,0.12579696234701163,destabilizing
+ALKBH5,SOX11,0.056064551486652854,destabilizing
+ALKBH5,EPB41L4B,0.11247247616933256,destabilizing
+ALKBH5,CACNA1B,0.10047465999578059,destabilizing
+ALKBH5,TBC1D5,0.06302614111979113,destabilizing
+ALKBH5,LRRTM4,0.11566469865987826,destabilizing
+ALKBH5,SIRPA,0.10599267149102427,destabilizing
+ALKBH5,PTEN,0.08439318243913776,destabilizing
+ALKBH5,FRY,0.14763404878581923,destabilizing
+ALKBH5,MACROD2,0.11884539298366839,destabilizing
+ALKBH5,SHANK2,0.20308726762573345,destabilizing
+ALKBH5,CDK12,0.1477688944307741,destabilizing
+ALKBH5,RFX7,0.13370440378615786,destabilizing
+ALKBH5,UBR5,0.0783917743796218,destabilizing
+ALKBH5,JARID2,0.08908784965861108,destabilizing
+ALKBH5,MPHOSPH8,0.10146481721376152,destabilizing
+ALKBH5,DIP2C,0.09804925215570438,destabilizing
+ALKBH5,UBR3,0.10914016318585495,destabilizing
+ALKBH5,MGAT5,0.06666125675886295,destabilizing
+ALKBH5,DLG2,0.08268468731721769,destabilizing
+ALKBH5,CHST12,0.20661599206015138,destabilizing
+ALKBH5,EML5,0.12215976214328565,destabilizing
+ALKBH5,PSME4,0.14267699173125048,destabilizing
+ALKBH5,TMEM106B,0.13387288589567398,destabilizing
+ALKBH5,RABGAP1L,0.0573247521716158,destabilizing
+ALKBH5,EPHA5,0.1099401783455351,destabilizing
+ALKBH5,KCNB2,0.11340795906182641,destabilizing
+ALKBH5,ZNF83,0.08825389704523572,destabilizing
+ALKBH5,SOX6,0.07399969170609028,destabilizing
+ALKBH5,ZNF521,0.13609351120259508,destabilizing
+ALKBH5,PLEKHA5,0.0633733313633708,destabilizing
+ALKBH5,NOVA1,0.1511146321268523,destabilizing
+ALKBH5,CCNY,0.13180080815460699,destabilizing
+ALKBH5,ARIH1,0.09659503867137746,destabilizing
+ALKBH5,EPB41L5,0.081880905093511,destabilizing
+ALKBH5,GPR158,0.12466359042855038,destabilizing
+ALKBH5,NCOA2,0.09624692612860743,destabilizing
+ALKBH5,ACACA,0.07024624192359966,destabilizing
+ALKBH5,CTNND2,0.08158451276781482,destabilizing
+ALKBH5,IFT172,0.12232727513897808,destabilizing
+ALKBH5,CCNT1,0.06652772787449135,destabilizing
+ALKBH5,SIK3,0.10219362201387998,destabilizing
+ALKBH5,CPEB3,0.13134550399199907,destabilizing
+ALKBH5,CADM2,0.07233112408161169,destabilizing
+ALKBH5,XKR6,0.15700602042652995,destabilizing
+ALKBH5,CADPS,0.07590539434722451,destabilizing
+ALKBH5,TCF20,0.15820395701245918,destabilizing
+ALKBH5,CDKAL1,0.0675754472081709,destabilizing
+ALKBH5,DGKI,0.109726954613462,destabilizing
+ALKBH5,EXOC6B,0.16085075376279592,destabilizing
+ALKBH5,MAGI3,0.12108044054423882,destabilizing
+ALKBH5,SBF2,0.0637449579670584,destabilizing
+ALKBH5,INPP4B,0.11878837807670924,destabilizing
+ALKBH5,PTPRS,0.12957582278387417,destabilizing
+ALKBH5,CBFA2T2,0.08297724325432972,destabilizing
+ALKBH5,SPDYE3,0.12640088726613158,destabilizing
+ALKBH5,DMD,0.19277281044286326,destabilizing
+ALKBH5,MCU,0.12440567841457982,destabilizing
+ALKBH5,SSH2,0.10165875382717024,destabilizing
+ALKBH5,DOCK3,0.14387741316703265,destabilizing
+ALKBH5,HS6ST3,0.10930507719643383,destabilizing
+ALKBH5,LPP,0.16737538962311027,destabilizing
+ALKBH5,STAG1,0.11368345017893876,destabilizing
+ALKBH5,CAPZA2,0.09117979130734241,destabilizing
+ALKBH5,ADGRL3,0.07360214761007156,destabilizing
+ALKBH5,UBE2R2,0.11627296912663047,destabilizing
+ALKBH5,GTF2IRD1,0.12017163748954456,destabilizing
+ALKBH5,CCBE1,0.060491296160725544,destabilizing
+ALKBH5,TTC28,0.0961376400915335,destabilizing
+ALKBH5,SBNO1,0.06562528153388396,destabilizing
+ALKBH5,RIMS2,0.06953495653683167,destabilizing
+ALKBH5,TRIO,0.07083055826787153,destabilizing
+ALKBH5,BTBD9,0.1487936690379777,destabilizing
+ALKBH5,CNGB1,0.14727863075182723,destabilizing
+ALKBH5,FMN2,0.12809353460593753,destabilizing
+ALKBH5,ENSG00000228222,0.17501660237485292,destabilizing
+ALKBH5,PRKN,0.14888383579375591,destabilizing
+ALKBH5,RASA2,0.12105546209050085,destabilizing
+ALKBH5,PPP1R12B,0.06875334902967704,destabilizing
+ALKBH5,FRMD4A,0.10327346491454502,destabilizing
+ALKBH5,SEMA6D,0.109293466199936,destabilizing
+ALKBH5,WIPF2,0.11066340155859206,destabilizing
+ALKBH5,DLEU1,0.17108219627623295,destabilizing
+ALKBH5,TSHZ2,0.07052828584176907,destabilizing
+ALKBH5,MED13L,0.07171145693371901,destabilizing
+ALKBH5,KAZN,0.12570479943084026,destabilizing
+ALKBH5,KANSL1,0.07582412176535358,destabilizing
+ALKBH5,FRMD5,0.10111110758196817,destabilizing
+ALKBH5,LINC00174,0.12483354423953266,destabilizing
+ALKBH5,PPM1E,0.1096454295290385,destabilizing
+ALKBH5,ARL3,0.08042996790235032,destabilizing
+ALKBH5,MBD5,0.0887593963397631,destabilizing
+ALKBH5,ELAVL3,0.12490949796324946,destabilizing
+ALKBH5,SLIT2,0.15577319811052662,destabilizing
+ALKBH5,CLASP1,0.0734253839156777,destabilizing
+ALKBH5,UNC5C,0.12692829642632344,destabilizing
+ALKBH5,CACNA2D3,-0.0549209043371544,stabilizing
+ALKBH5,RC3H1,0.09895366160303712,destabilizing
+ALKBH5,NEGR1,0.12449163040168314,destabilizing
+ALKBH5,ENOX1,0.15215554921003788,destabilizing
+ALKBH5,SCUBE1,0.0801326175498477,destabilizing
+ALKBH5,GPHN,0.09869335886555006,destabilizing
+ALKBH5,NAV3,0.1721109821297391,destabilizing
+ALKBH5,TOMM22,0.15554511694257311,destabilizing
+ALKBH5,MBNL2,0.060030947019183774,destabilizing
+ALKBH5,ANKFN1,0.07398002478286919,destabilizing
+ALKBH5,MAGI2,0.05716258274206831,destabilizing
+ALKBH5,LSAMP,0.07795960442482333,destabilizing
+ALKBH5,AKAP6,0.14256168420873414,destabilizing
+ALKBH5,ZBTB20,0.09145073110283893,destabilizing
+ALKBH5,GRIK2,0.11604409827296926,destabilizing
+ALKBH5,SOX5,0.07439212864620966,destabilizing
+ALKBH5,LRRC37A3,0.1858009498163019,destabilizing
+ALKBH5,EYS,0.07742901073286014,destabilizing
+ALKBH5,ARID1B,0.0843555272263007,destabilizing
+ALKBH5,PRKCE,0.08911773079553666,destabilizing
+ALKBH5,RBFOX1,-0.08559029193417589,stabilizing
+ALKBH5,SDK1,0.07362399745642861,destabilizing
+ALKBH5,NRG1,0.059001086382236306,destabilizing
+ALKBH5,MLLT3,0.16577428824592036,destabilizing
+ALKBH5,FMN1,0.07628203538833936,destabilizing
+ALKBH5,ADGRB3,0.07757173301378271,destabilizing
+ALKBH5,ROBO1,0.11991068853770541,destabilizing
+ALKBH5,SYPL1,0.06061952547810774,destabilizing
+ALKBH5,PTPRD,0.08600079514053217,destabilizing
+ALKBH5,FAM155A,0.12886776116141488,destabilizing
+ALKBH5,LARP1B,0.11078625285058169,destabilizing
+FTO,INPP4B,0.07575907268564279,destabilizing
+FTO,UNC5C,0.0767180720869161,destabilizing
+EWSR1,TRERF1,0.11927213703370179,destabilizing
+EWSR1,SORCS1,0.059182977848803366,destabilizing
+EWSR1,PDE3A,0.11218178169028714,destabilizing
+EWSR1,UNC79,0.1362827372410725,destabilizing
+EWSR1,DOC2B,0.11169393168768887,destabilizing
+EWSR1,TMTC2,0.13070821292969342,destabilizing
+EWSR1,KALRN,0.08926158769965782,destabilizing
+EWSR1,CHD1,0.06292943097178284,destabilizing
+EWSR1,MTMR7,0.13767580795200865,destabilizing
+EWSR1,EIF4E,0.15841366640718835,destabilizing
+EWSR1,SOX11,0.0705468701950052,destabilizing
+EWSR1,CACNA1B,0.08718613872700005,destabilizing
+EWSR1,PTEN,0.09027521435572156,destabilizing
+EWSR1,FRY,0.14388876069938747,destabilizing
+EWSR1,MACROD2,0.14800099490440816,destabilizing
+EWSR1,SHANK2,0.18069846933076544,destabilizing
+EWSR1,CDK12,0.1795881123084179,destabilizing
+EWSR1,RFX7,0.1115341637095978,destabilizing
+EWSR1,JARID2,0.05413173387123882,destabilizing
+EWSR1,MPHOSPH8,0.11456151158131268,destabilizing
+EWSR1,DIP2C,0.07223691305244788,destabilizing
+EWSR1,ZNF423,0.05742273314640674,destabilizing
+EWSR1,DLG2,0.07453744625260235,destabilizing
+EWSR1,CHST12,0.20498916918434945,destabilizing
+EWSR1,EML5,0.10976727055547188,destabilizing
+EWSR1,CENPP,0.23376938435900899,destabilizing
+EWSR1,PSME4,0.09204802438723171,destabilizing
+EWSR1,TMEM106B,0.12506026917814633,destabilizing
+EWSR1,EPHA5,0.08846775337678196,destabilizing
+EWSR1,KCNB2,0.14198108139261087,destabilizing
+EWSR1,ZNF83,0.10387483112876923,destabilizing
+EWSR1,SOX6,0.10008664374071383,destabilizing
+EWSR1,ZNF521,0.11715506098931311,destabilizing
+EWSR1,PLEKHA5,0.07135757214157737,destabilizing
+EWSR1,NOVA1,0.13018370464416876,destabilizing
+EWSR1,CCNY,0.1358453039684784,destabilizing
+EWSR1,ARIH1,0.0676793204538861,destabilizing
+EWSR1,EPB41L5,0.07889194451688444,destabilizing
+EWSR1,GPR158,0.09694285200847927,destabilizing
+EWSR1,NCOA2,0.067247702367218,destabilizing
+EWSR1,MARCKS,0.06173576342452825,destabilizing
+EWSR1,ALK,0.1907699548316171,destabilizing
+EWSR1,IFT172,0.1198548329205879,destabilizing
+EWSR1,CCNT1,0.07141514222002941,destabilizing
+EWSR1,DTWD2,0.19657000776262112,destabilizing
+EWSR1,SIK3,0.08750869308554703,destabilizing
+EWSR1,CPEB3,0.13493447799529873,destabilizing
+EWSR1,CADM2,0.07146435779183968,destabilizing
+EWSR1,XKR6,0.13701570872777108,destabilizing
+EWSR1,RMND5A,0.06317947118544036,destabilizing
+EWSR1,CDKAL1,0.07102132552997811,destabilizing
+EWSR1,DGKI,0.0876645379123992,destabilizing
+EWSR1,EXOC6B,0.11015267533098379,destabilizing
+EWSR1,MAGI3,0.13323311416746964,destabilizing
+EWSR1,SBF2,0.07510771958183333,destabilizing
+EWSR1,INPP4B,0.10385107230219609,destabilizing
+EWSR1,PTPRS,0.14980365656730155,destabilizing
+EWSR1,DMD,0.1487372222641595,destabilizing
+EWSR1,SSH2,0.0834705221900646,destabilizing
+EWSR1,DOCK3,0.1195458178787067,destabilizing
+EWSR1,HS6ST3,0.11289547117247099,destabilizing
+EWSR1,STAG1,0.07315904870862867,destabilizing
+EWSR1,CAPZA2,0.13774853137839604,destabilizing
+EWSR1,ADGRL3,0.05908324012018793,destabilizing
+EWSR1,PHACTR1,0.07841773693448698,destabilizing
+EWSR1,UBE2R2,0.09962141451034905,destabilizing
+EWSR1,GTF2IRD1,0.06424365184694321,destabilizing
+EWSR1,TTC28,0.10239899420095427,destabilizing
+EWSR1,SBNO1,0.06652657534775208,destabilizing
+EWSR1,RIMS2,0.057913539616331416,destabilizing
+EWSR1,BTBD9,0.08836499012922605,destabilizing
+EWSR1,CNGB1,0.11124969862296857,destabilizing
+EWSR1,FMN2,0.08222864595969315,destabilizing
+EWSR1,ENSG00000228222,0.2423112349883776,destabilizing
+EWSR1,SYN3,0.051290104172991444,destabilizing
+EWSR1,PRKN,0.09901158466089605,destabilizing
+EWSR1,RASA2,0.14727524112214074,destabilizing
+EWSR1,PPP1R12B,0.06658640315241066,destabilizing
+EWSR1,FRMD4A,0.07102977713975399,destabilizing
+EWSR1,SEMA6D,0.0841870856192957,destabilizing
+EWSR1,WIPF2,0.15495108143555542,destabilizing
+EWSR1,DLEU1,0.1317365713247514,destabilizing
+EWSR1,TSHZ2,0.06847586325976919,destabilizing
+EWSR1,KAZN,0.07217438601784537,destabilizing
+EWSR1,FRMD5,0.07618170260769612,destabilizing
+EWSR1,LINC00174,0.13801563560475597,destabilizing
+EWSR1,ARL3,0.1007696998199597,destabilizing
+EWSR1,MBD5,0.10687288161971654,destabilizing
+EWSR1,ELAVL3,0.11030411629669112,destabilizing
+EWSR1,SLIT2,0.1179813520868241,destabilizing
+EWSR1,CLASP1,0.07658105423382926,destabilizing
+EWSR1,UNC5C,0.1022148428690822,destabilizing
+EWSR1,NEGR1,0.1134860757531001,destabilizing
+EWSR1,ENOX1,0.1687310964893061,destabilizing
+EWSR1,GPHN,0.07556253812496924,destabilizing
+EWSR1,NAV3,0.0913195429524104,destabilizing
+EWSR1,EBF1,0.061561800102676464,destabilizing
+EWSR1,TOMM22,0.14895186419259143,destabilizing
+EWSR1,ANKFN1,0.07088529594502335,destabilizing
+EWSR1,LSAMP,0.07289992990855716,destabilizing
+EWSR1,AKAP6,0.09431150952885156,destabilizing
+EWSR1,TMED2,0.09694538485559016,destabilizing
+EWSR1,ZBTB20,0.11574887537776425,destabilizing
+EWSR1,GRIK2,0.09333716181816507,destabilizing
+EWSR1,LRRC37A3,0.16223862430615724,destabilizing
+EWSR1,EYS,0.07230371433791659,destabilizing
+EWSR1,RBFOX1,-0.0575645997541282,stabilizing
+EWSR1,MLLT3,0.22862996018064172,destabilizing
+EWSR1,ADGRB3,0.05732194678937074,destabilizing
+EWSR1,SYPL1,0.06488008821894854,destabilizing
+EWSR1,PTPRD,0.10755383811374493,destabilizing
+EWSR1,FAM155A,0.15545314116013098,destabilizing
+EWSR1,LARP1B,0.11473595311987136,destabilizing
+FUS,TRERF1,0.14567645235989124,destabilizing
+FUS,PDE3A,0.11091780137045515,destabilizing
+FUS,UNC79,0.11937045374176222,destabilizing
+FUS,DOC2B,0.08601351658345399,destabilizing
+FUS,TMTC2,0.13592172053529789,destabilizing
+FUS,KALRN,0.07740925214012756,destabilizing
+FUS,TOX,0.09311637339278357,destabilizing
+FUS,BRAF,0.054850597177234374,destabilizing
+FUS,RYR2,0.18765576281639912,destabilizing
+FUS,MTMR7,0.13758805202108335,destabilizing
+FUS,EIF4E,0.17191779682134417,destabilizing
+FUS,CACNA1B,0.07793758466041854,destabilizing
+FUS,WSB1,0.0693969397890274,destabilizing
+FUS,LRRTM4,0.07037321987160504,destabilizing
+FUS,PTEN,0.07673218376004902,destabilizing
+FUS,FRY,0.14638267102107771,destabilizing
+FUS,RUNX1T1,0.07171345614449258,destabilizing
+FUS,MACROD2,0.1228931461344649,destabilizing
+FUS,SHANK2,0.14531435661356965,destabilizing
+FUS,CDK12,0.20245055257079506,destabilizing
+FUS,RFX7,0.1062600278663329,destabilizing
+FUS,MPHOSPH8,0.11443304830420223,destabilizing
+FUS,CHST12,0.1580753246084275,destabilizing
+FUS,EML5,0.11888490790613664,destabilizing
+FUS,CENPP,0.3367793110162639,destabilizing
+FUS,PSME4,0.09526751331177476,destabilizing
+FUS,TMEM106B,0.09191554999600414,destabilizing
+FUS,EPHA5,0.0925253890604829,destabilizing
+FUS,KCNB2,0.19768811200425268,destabilizing
+FUS,ZNF83,0.09340706297283477,destabilizing
+FUS,SOX6,0.11545591208630067,destabilizing
+FUS,ZNF521,0.11008216049912173,destabilizing
+FUS,PLEKHA5,0.08381669269676552,destabilizing
+FUS,DTL,-0.1341680033843668,stabilizing
+FUS,NOVA1,0.17656703501102217,destabilizing
+FUS,CCNY,0.0924700915908366,destabilizing
+FUS,ARIH1,0.06928590018948952,destabilizing
+FUS,GPR158,0.11085227518707831,destabilizing
+FUS,ALK,0.2742469089097087,destabilizing
+FUS,IFT172,0.10966421357866074,destabilizing
+FUS,CCNT1,0.08448345689825779,destabilizing
+FUS,DTWD2,0.2727248229022015,destabilizing
+FUS,SIK3,0.0793795624271153,destabilizing
+FUS,CPEB3,0.14826024451132824,destabilizing
+FUS,XKR6,0.1307781409074188,destabilizing
+FUS,CADPS,0.07608775938669071,destabilizing
+FUS,FGF13,0.06416165449315013,destabilizing
+FUS,TCF20,0.08669480170950002,destabilizing
+FUS,CDKAL1,0.09257294507351684,destabilizing
+FUS,DGKI,0.102700448188646,destabilizing
+FUS,EXOC6B,0.10819541937258495,destabilizing
+FUS,MAGI3,0.12119258381904165,destabilizing
+FUS,INPP4B,0.08836630333543903,destabilizing
+FUS,TMEM178B,0.06866486177067398,destabilizing
+FUS,DMD,0.19092819960960342,destabilizing
+FUS,EIF4G3,0.059250051825787194,destabilizing
+FUS,MCU,0.10411812425590228,destabilizing
+FUS,SSH2,0.08622265747746727,destabilizing
+FUS,DOCK3,0.14066817834521694,destabilizing
+FUS,STAG1,0.07341147440942007,destabilizing
+FUS,CAPZA2,0.1122146021713085,destabilizing
+FUS,PHACTR1,0.10775380694288067,destabilizing
+FUS,UBE2R2,0.10600871729297333,destabilizing
+FUS,GTF2IRD1,0.05900338327943938,destabilizing
+FUS,JMJD1C,0.05416736254833271,destabilizing
+FUS,TTC28,0.0782969157360176,destabilizing
+FUS,RIMS2,0.08824852789198274,destabilizing
+FUS,BTBD9,0.10304516209381807,destabilizing
+FUS,CNGB1,0.0898849313043883,destabilizing
+FUS,FMN2,0.06979598401442905,destabilizing
+FUS,ENSG00000228222,0.1734090936623452,destabilizing
+FUS,SYN3,0.06488640380340802,destabilizing
+FUS,RASA2,0.14929961592118995,destabilizing
+FUS,PPP1R12B,0.06682415302216325,destabilizing
+FUS,FRMD4A,0.07837927951903345,destabilizing
+FUS,SEMA6D,0.1065605059418518,destabilizing
+FUS,WIPF2,0.13057070918992428,destabilizing
+FUS,DLEU1,0.1405441536786321,destabilizing
+FUS,TSHZ2,0.07263593568183249,destabilizing
+FUS,KAZN,0.07345472661477147,destabilizing
+FUS,KANSL1,0.07542573689455315,destabilizing
+FUS,FRMD5,0.08581081125271892,destabilizing
+FUS,LINC00174,0.11176037906791987,destabilizing
+FUS,ARL3,0.10729066874126728,destabilizing
+FUS,MBD5,0.07009183557817213,destabilizing
+FUS,ELAVL3,0.11683192569168191,destabilizing
+FUS,SLIT2,0.0848571775982836,destabilizing
+FUS,CLASP1,0.08991372719858762,destabilizing
+FUS,UNC5C,0.1208865860464222,destabilizing
+FUS,NEGR1,0.12795395576097007,destabilizing
+FUS,ENOX1,0.16791187325456447,destabilizing
+FUS,TOMM22,0.11492943979120349,destabilizing
+FUS,ANKFN1,0.07260826842402554,destabilizing
+FUS,AKAP6,0.10964770012597067,destabilizing
+FUS,TMED2,0.07948862176150152,destabilizing
+FUS,ZBTB20,0.12041978217858051,destabilizing
+FUS,GRIK2,0.0655337445564468,destabilizing
+FUS,SOX5,0.06614896124460581,destabilizing
+FUS,LRRC37A3,0.14315735764868048,destabilizing
+FUS,EYS,0.07510316027736218,destabilizing
+FUS,RORA,0.05231618971834701,destabilizing
+FUS,MLLT3,0.17716761305094145,destabilizing
+FUS,ROBO1,0.07473949631718178,destabilizing
+FUS,SYPL1,0.07546124529416508,destabilizing
+FUS,PTPRD,0.10680439475613045,destabilizing
+FUS,FAM155A,0.12757037540958788,destabilizing
+FUS,LARP1B,0.0702326343281684,destabilizing
+TAF15,TRERF1,0.08719204017304373,destabilizing
+TAF15,SORCS1,0.060842295141182695,destabilizing
+TAF15,UNC79,0.0895980695447562,destabilizing
+TAF15,MTMR7,0.0860257871976522,destabilizing
+TAF15,EIF4E,0.12306053528832504,destabilizing
+TAF15,FRY,0.08661122694142621,destabilizing
+TAF15,MACROD2,0.07491192501448433,destabilizing
+TAF15,CDK12,0.10823510412178294,destabilizing
+TAF15,MPHOSPH8,0.06529044185000518,destabilizing
+TAF15,CHST12,0.13814981488564604,destabilizing
+TAF15,EML5,0.10081588033235117,destabilizing
+TAF15,CENPP,0.14573820700914925,destabilizing
+TAF15,PSME4,0.06967519981339708,destabilizing
+TAF15,TMEM106B,0.07412545743412537,destabilizing
+TAF15,KCNB2,0.08867443540697213,destabilizing
+TAF15,ZNF83,0.07907495712626995,destabilizing
+TAF15,SOX6,0.07274934616374648,destabilizing
+TAF15,NOVA1,0.1036948754173273,destabilizing
+TAF15,CCNY,0.0809141826959328,destabilizing
+TAF15,ALK,0.10238366508463922,destabilizing
+TAF15,IFT172,0.07130836855636824,destabilizing
+TAF15,XKR6,0.0865147983464905,destabilizing
+TAF15,TCF20,0.10278777797728071,destabilizing
+TAF15,EXOC6B,0.10122889444112625,destabilizing
+TAF15,MAGI3,0.08197705273618087,destabilizing
+TAF15,DMD,0.09477049756389505,destabilizing
+TAF15,MCU,0.0737740948030454,destabilizing
+TAF15,SSH2,0.06378477645900016,destabilizing
+TAF15,DOCK3,0.09280959581756856,destabilizing
+TAF15,BTBD9,0.08329527563544291,destabilizing
+TAF15,ENSG00000228222,0.13387221608774125,destabilizing
+TAF15,PRKN,0.10074674797221196,destabilizing
+TAF15,WIPF2,0.09231586350154725,destabilizing
+TAF15,DLEU1,0.12652617641675598,destabilizing
+TAF15,FRMD5,0.06610813879322568,destabilizing
+TAF15,LINC00174,0.0674725975505757,destabilizing
+TAF15,SLIT2,0.11015494828405727,destabilizing
+TAF15,NEGR1,0.08018805588204773,destabilizing
+TAF15,TOMM22,0.07931626308042065,destabilizing
+TAF15,ZBTB20,0.08382962589555853,destabilizing
+TAF15,LRRC37A3,0.10239038065994975,destabilizing
+TAF15,EYS,0.05642809574493609,destabilizing
+TAF15,MLLT3,0.10335445614776294,destabilizing
+SFPQ,TRERF1,0.0873661274281534,destabilizing
+SFPQ,SORCS1,0.09438902046295261,destabilizing
+SFPQ,PDE3A,0.12081768605496063,destabilizing
+SFPQ,UNC79,0.11866848003811872,destabilizing
+SFPQ,DOC2B,0.07216258070840577,destabilizing
+SFPQ,TMTC2,0.10032210047091256,destabilizing
+SFPQ,KALRN,0.08272151361425016,destabilizing
+SFPQ,CHD1,0.0873708084769549,destabilizing
+SFPQ,PPARD,0.07718736710668771,destabilizing
+SFPQ,TOX,0.07838922213124914,destabilizing
+SFPQ,RYR2,0.1244190098739325,destabilizing
+SFPQ,MTMR7,0.0939227668132051,destabilizing
+SFPQ,EIF4E,0.10758646382245429,destabilizing
+SFPQ,LRRTM4,0.08757620038848209,destabilizing
+SFPQ,FRY,0.09541694683467897,destabilizing
+SFPQ,MACROD2,0.09195525633034397,destabilizing
+SFPQ,SHANK2,0.14274665311837406,destabilizing
+SFPQ,CDK12,0.1582493492569843,destabilizing
+SFPQ,RFX7,0.11342087120959579,destabilizing
+SFPQ,MPHOSPH8,0.0935464989206173,destabilizing
+SFPQ,DIP2C,0.07081402146770727,destabilizing
+SFPQ,DLG2,0.06471634156302779,destabilizing
+SFPQ,CHST12,0.12496702310385341,destabilizing
+SFPQ,EML5,0.1177878830362183,destabilizing
+SFPQ,CENPP,0.14336195300760418,destabilizing
+SFPQ,PSME4,0.11274498159186576,destabilizing
+SFPQ,TMEM106B,0.10345299211516289,destabilizing
+SFPQ,EPHA5,0.07283747803801041,destabilizing
+SFPQ,KCNB2,0.13686873215903791,destabilizing
+SFPQ,ZNF83,0.07662519204524719,destabilizing
+SFPQ,SOX6,0.0654118139766519,destabilizing
+SFPQ,ZNF521,0.07174120926235746,destabilizing
+SFPQ,PLEKHA5,0.05828016996560063,destabilizing
+SFPQ,NOVA1,0.12214108420965505,destabilizing
+SFPQ,CCNY,0.10242905715418056,destabilizing
+SFPQ,ARIH1,0.08512638034958164,destabilizing
+SFPQ,EPB41L5,0.07820039594886168,destabilizing
+SFPQ,GPR158,0.08389838003466064,destabilizing
+SFPQ,ALK,0.10792121582836012,destabilizing
+SFPQ,IFT172,0.08972513157547223,destabilizing
+SFPQ,CCNT1,0.06394860957833552,destabilizing
+SFPQ,SIK3,0.09467779911928383,destabilizing
+SFPQ,CPEB3,0.15413818203336052,destabilizing
+SFPQ,XKR6,0.11410433418685854,destabilizing
+SFPQ,CADPS,0.07379471785190689,destabilizing
+SFPQ,TCF20,0.10736550484349405,destabilizing
+SFPQ,CDKAL1,0.08776205718631283,destabilizing
+SFPQ,DGKI,0.09056883916060487,destabilizing
+SFPQ,EXOC6B,0.1385706070493731,destabilizing
+SFPQ,MAGI3,0.10451738218326889,destabilizing
+SFPQ,INPP4B,0.07743428687379073,destabilizing
+SFPQ,DMD,0.15616728485264844,destabilizing
+SFPQ,MCU,0.09709992522702048,destabilizing
+SFPQ,SSH2,0.07429581298442271,destabilizing
+SFPQ,DOCK3,0.12374150680235126,destabilizing
+SFPQ,HS6ST3,0.10268495442846003,destabilizing
+SFPQ,LPP,0.10182310026931547,destabilizing
+SFPQ,STAG1,0.07373198203827622,destabilizing
+SFPQ,CAPZA2,0.09350926062458151,destabilizing
+SFPQ,ADGRL3,0.059956970080108314,destabilizing
+SFPQ,PHACTR1,0.06046934444257739,destabilizing
+SFPQ,UBE2R2,0.08395993982659548,destabilizing
+SFPQ,GTF2IRD1,0.06839791139955563,destabilizing
+SFPQ,RIMS2,0.07399925945769718,destabilizing
+SFPQ,BTBD9,0.11135451881254475,destabilizing
+SFPQ,CNGB1,0.09500755311098114,destabilizing
+SFPQ,ENSG00000228222,0.15630727048190032,destabilizing
+SFPQ,PRKN,0.10408934710190786,destabilizing
+SFPQ,RASA2,0.0974217214287147,destabilizing
+SFPQ,FRMD4A,0.07146070620590834,destabilizing
+SFPQ,SEMA6D,0.07661471542107151,destabilizing
+SFPQ,WIPF2,0.09509806106259532,destabilizing
+SFPQ,TSHZ2,0.06847517843516573,destabilizing
+SFPQ,FRMD5,0.10539710671283042,destabilizing
+SFPQ,LINC00174,0.08234458415645192,destabilizing
+SFPQ,PPM1E,0.07304425106712555,destabilizing
+SFPQ,ARL3,0.09114633218647333,destabilizing
+SFPQ,ELAVL3,0.08498816519278239,destabilizing
+SFPQ,SLIT2,0.10117035619817043,destabilizing
+SFPQ,UNC5C,0.06538244680649521,destabilizing
+SFPQ,RC3H1,0.06594978629932007,destabilizing
+SFPQ,NEGR1,0.10676164381918403,destabilizing
+SFPQ,ENOX1,0.15021261935483762,destabilizing
+SFPQ,GPHN,0.06303096975270613,destabilizing
+SFPQ,NAV3,0.11292561014784327,destabilizing
+SFPQ,TOMM22,0.09677444347918102,destabilizing
+SFPQ,AKAP6,0.08916800666183913,destabilizing
+SFPQ,ZBTB20,0.09163284618365292,destabilizing
+SFPQ,GRIK2,0.06928734525650479,destabilizing
+SFPQ,LRRC37A3,0.11108615185281369,destabilizing
+SFPQ,RBFOX1,-0.053569050983175624,stabilizing
+SFPQ,MLLT3,0.1343386123710236,destabilizing
+SFPQ,SYPL1,0.05565571442173938,destabilizing
+SFPQ,PTPRD,0.07416437950542298,destabilizing
+SFPQ,FAM155A,0.11165177062887341,destabilizing
+SFPQ,LARP1B,0.07554789045161527,destabilizing
+NONO,TRERF1,0.2230283262927597,destabilizing
+NONO,SORCS1,0.146511102301934,destabilizing
+NONO,NCOA1,0.0669538617502621,destabilizing
+NONO,COPA,0.09151375072329064,destabilizing
+NONO,FCHSD2,0.09486850183766396,destabilizing
+NONO,PDE3A,0.20845159956233006,destabilizing
+NONO,UNC79,0.23983663477116288,destabilizing
+NONO,DOC2B,0.1423157895649359,destabilizing
+NONO,TMTC2,0.20077570728976973,destabilizing
+NONO,KALRN,0.15058064764825307,destabilizing
+NONO,CHD1,0.10908086182808985,destabilizing
+NONO,PAK3,0.058273869997357765,destabilizing
+NONO,UBE2E2,0.08466916330163614,destabilizing
+NONO,PPARD,0.09523731041294548,destabilizing
+NONO,TOX,0.09989612560832711,destabilizing
+NONO,BRAF,0.06938502194568778,destabilizing
+NONO,RYR2,0.18140821241505248,destabilizing
+NONO,MTMR7,0.23636367599486552,destabilizing
+NONO,EIF4E,0.21807870015524958,destabilizing
+NONO,EPB41L4B,0.1284364089028091,destabilizing
+NONO,CACNA1B,0.14263207194447644,destabilizing
+NONO,TBC1D5,0.06933078433248285,destabilizing
+NONO,LRRTM4,0.1334211747719983,destabilizing
+NONO,SIRPA,0.1576645673521898,destabilizing
+NONO,PTEN,0.15241697388111497,destabilizing
+NONO,FRY,0.23038365618515066,destabilizing
+NONO,MACROD2,0.17415060351789918,destabilizing
+NONO,SHANK2,0.2309080843669383,destabilizing
+NONO,CDK12,0.26849384060843207,destabilizing
+NONO,RFX7,0.1981005601786327,destabilizing
+NONO,UBR5,0.09719399983054212,destabilizing
+NONO,JARID2,0.12497891339758326,destabilizing
+NONO,MPHOSPH8,0.16465836606445503,destabilizing
+NONO,DIP2C,0.13494914261962476,destabilizing
+NONO,ZNF423,0.08440654704495952,destabilizing
+NONO,UBR3,0.12140392804010024,destabilizing
+NONO,MGAT5,0.07065479729207015,destabilizing
+NONO,DLG2,0.1575853551887165,destabilizing
+NONO,CHST12,0.2900462531842933,destabilizing
+NONO,EML5,0.20902018895618207,destabilizing
+NONO,CENPP,0.24865497044310209,destabilizing
+NONO,PSME4,0.17718860830226382,destabilizing
+NONO,TMEM106B,0.18279927714474126,destabilizing
+NONO,EPHA5,0.15655998368627708,destabilizing
+NONO,KCNB2,0.1993510085267888,destabilizing
+NONO,ZNF83,0.1318354184800264,destabilizing
+NONO,SOX6,0.12080992710131254,destabilizing
+NONO,ZNF521,0.17691782252940863,destabilizing
+NONO,PLEKHA5,0.13635609435100088,destabilizing
+NONO,NOVA1,0.2152278697967087,destabilizing
+NONO,CCNY,0.17486511151726186,destabilizing
+NONO,ARIH1,0.138847529937674,destabilizing
+NONO,FAM171B,0.052488260886518846,destabilizing
+NONO,EPB41L5,0.13019480539941297,destabilizing
+NONO,GPR158,0.2240294298406028,destabilizing
+NONO,NCOA2,0.14047546673427036,destabilizing
+NONO,ALK,0.2630408043234524,destabilizing
+NONO,ACACA,0.0913147397377731,destabilizing
+NONO,ARHGAP26,0.0658234265651014,destabilizing
+NONO,CTNND2,0.08977805486158673,destabilizing
+NONO,IFT172,0.17859966017042722,destabilizing
+NONO,CCNT1,0.12198911806357743,destabilizing
+NONO,DTWD2,0.29989829946502033,destabilizing
+NONO,SIK3,0.1381082112914465,destabilizing
+NONO,CPEB3,0.23660147554436708,destabilizing
+NONO,CADM2,0.07613238280037155,destabilizing
+NONO,XKR6,0.2118763273515341,destabilizing
+NONO,RMND5A,0.0716634075006975,destabilizing
+NONO,CADPS,0.120553292392804,destabilizing
+NONO,FGF13,0.09896963708791602,destabilizing
+NONO,TCF20,0.18689952956703826,destabilizing
+NONO,CDKAL1,0.13624780363639397,destabilizing
+NONO,DGKI,0.14834316668364358,destabilizing
+NONO,EXOC6B,0.2350989431639563,destabilizing
+NONO,MAGI3,0.18828360567223537,destabilizing
+NONO,SBF2,0.09472716708067908,destabilizing
+NONO,INPP4B,0.17772612776433852,destabilizing
+NONO,ERC1,0.08464072662458169,destabilizing
+NONO,PTPRS,0.22746793053422984,destabilizing
+NONO,CBFA2T2,0.07098653771595499,destabilizing
+NONO,SPDYE3,0.1320677288304693,destabilizing
+NONO,TMEM178B,0.08713107773675993,destabilizing
+NONO,CACNA2D1,0.06164474201096615,destabilizing
+NONO,DMD,0.2680202405254838,destabilizing
+NONO,EIF4G3,0.07267127542941094,destabilizing
+NONO,MCU,0.17946738889618122,destabilizing
+NONO,SSH2,0.15036209698842268,destabilizing
+NONO,DOCK3,0.21769853182887672,destabilizing
+NONO,HS6ST3,0.21161350432555787,destabilizing
+NONO,LPP,0.19896974698231376,destabilizing
+NONO,STAG1,0.15926715534728478,destabilizing
+NONO,CAPZA2,0.1942892378772318,destabilizing
+NONO,ADGRL3,0.09902356664313058,destabilizing
+NONO,PHACTR1,0.10408981059281594,destabilizing
+NONO,UBE2R2,0.18571212426013559,destabilizing
+NONO,GTF2IRD1,0.12595644450217258,destabilizing
+NONO,CCBE1,0.08838013264760537,destabilizing
+NONO,FTX,0.06695246872878724,destabilizing
+NONO,VAPA,0.07178007048561756,destabilizing
+NONO,TTC28,0.10765198325661657,destabilizing
+NONO,SBNO1,0.08894366623768338,destabilizing
+NONO,RIMS2,0.10950276280831109,destabilizing
+NONO,IGF1R,0.06726821314947395,destabilizing
+NONO,TRIO,0.06844989544845607,destabilizing
+NONO,KCND2,0.05964150622129083,destabilizing
+NONO,BTBD9,0.1966571557889868,destabilizing
+NONO,CNGB1,0.1976469700084653,destabilizing
+NONO,FMN2,0.13223951761085523,destabilizing
+NONO,ENSG00000228222,0.26965154589385737,destabilizing
+NONO,ATXN1,0.08072078859418795,destabilizing
+NONO,SYN3,0.06885551583110447,destabilizing
+NONO,PRKN,0.2165741457763318,destabilizing
+NONO,RASA2,0.18483749240477199,destabilizing
+NONO,PPP1R12B,0.1308008753288004,destabilizing
+NONO,FRMD4A,0.11615003234441747,destabilizing
+NONO,CAMK1D,0.07726976548938588,destabilizing
+NONO,SEMA6D,0.15344086101581064,destabilizing
+NONO,WIPF2,0.19393222741043892,destabilizing
+NONO,WWOX,0.05404690631168341,destabilizing
+NONO,DLEU1,0.27297427697091897,destabilizing
+NONO,TSHZ2,0.10175246188885731,destabilizing
+NONO,MED13L,0.11031362291989087,destabilizing
+NONO,AFF3,0.08625906804192736,destabilizing
+NONO,KAZN,0.1581497854116037,destabilizing
+NONO,KANSL1,0.09530950316933406,destabilizing
+NONO,FRMD5,0.1609247759356792,destabilizing
+NONO,LINC00174,0.1815309725745843,destabilizing
+NONO,PPM1E,0.14767116753045217,destabilizing
+NONO,ARL3,0.12095543024912428,destabilizing
+NONO,MBD5,0.14798672634311255,destabilizing
+NONO,ELAVL3,0.14521916197180043,destabilizing
+NONO,SLIT2,0.2183696022926277,destabilizing
+NONO,SLC8A1,0.07338407345596651,destabilizing
+NONO,CLASP1,0.12266289595112932,destabilizing
+NONO,UNC5C,0.17613180458400554,destabilizing
+NONO,CACNA2D3,-0.05988272301807545,stabilizing
+NONO,RC3H1,0.10192316505926055,destabilizing
+NONO,NEGR1,0.18060551643573294,destabilizing
+NONO,ENOX1,0.2709580650119047,destabilizing
+NONO,SCUBE1,0.10534660379416845,destabilizing
+NONO,GPHN,0.14394008767516855,destabilizing
+NONO,NAV3,0.1784352708775639,destabilizing
+NONO,TOMM22,0.229454179539932,destabilizing
+NONO,MBNL2,0.06939334670558431,destabilizing
+NONO,ANKFN1,0.07367299126838199,destabilizing
+NONO,MAGI2,0.08150648684088928,destabilizing
+NONO,LSAMP,0.11316330753033431,destabilizing
+NONO,AKAP6,0.1645668285621777,destabilizing
+NONO,TMED2,0.1429075636684417,destabilizing
+NONO,ZBTB20,0.19204966872574217,destabilizing
+NONO,GRIK2,0.17845521214224375,destabilizing
+NONO,SOX5,0.11232865832905427,destabilizing
+NONO,LRRC37A3,0.20586685582970116,destabilizing
+NONO,TMEM132C,0.05265210215661725,destabilizing
+NONO,EYS,0.13066415068323597,destabilizing
+NONO,ARID1B,0.10970697544247525,destabilizing
+NONO,PRKCE,0.10332993639761487,destabilizing
+NONO,RBFOX1,-0.07173592015004394,stabilizing
+NONO,SDK1,0.09081195529928793,destabilizing
+NONO,NRG1,0.07801749793187146,destabilizing
+NONO,RORA,0.06608522671376664,destabilizing
+NONO,MLLT3,0.24634379954021457,destabilizing
+NONO,FMN1,0.07923774649173636,destabilizing
+NONO,ADGRB3,0.10577911901667522,destabilizing
+NONO,ROBO1,0.17102512421694202,destabilizing
+NONO,SYPL1,0.10981629856712749,destabilizing
+NONO,PTPRD,0.1577770551280582,destabilizing
+NONO,FAM155A,0.2248867943518429,destabilizing
+NONO,LARP1B,0.18731485012994437,destabilizing
+NOVA1,NOVA1,-0.2626768539645661,stabilizing
+NOVA2,TRERF1,0.07710091377545492,destabilizing
+NOVA2,CHST12,0.12007496422036865,destabilizing
+SRRM4,SORCS1,0.05752313873196969,destabilizing
+SRRM4,MTMR7,0.0883190900945133,destabilizing
+SRRM4,EPB41L4B,0.06283942984068228,destabilizing
+SRRM4,SHANK2,0.11652174992893456,destabilizing
+SRRM4,CDK12,0.08642764368536703,destabilizing
+SRRM4,PSME4,0.08161734020137835,destabilizing
+SRRM4,EPB41L5,0.06369109585724551,destabilizing
+SRRM4,TCF20,0.0811077900946945,destabilizing
+SRRM4,EXOC6B,0.10118122340408879,destabilizing
+SRRM4,DMD,0.08109065845301591,destabilizing
+SRRM4,GTF2IRD1,0.06264396195145006,destabilizing
+SRRM4,NEGR1,0.08382337097516157,destabilizing
+SF3B1,TRERF1,0.09122576666908609,destabilizing
+SF3B1,UNC79,0.101040029402781,destabilizing
+SF3B1,DOC2B,0.060515579005428914,destabilizing
+SF3B1,TMTC2,0.08459962714770577,destabilizing
+SF3B1,LRRTM4,0.07625542185809442,destabilizing
+SF3B1,FRY,0.09749594161606347,destabilizing
+SF3B1,MACROD2,0.09135912707192341,destabilizing
+SF3B1,SHANK2,0.11182403977795262,destabilizing
+SF3B1,CDK12,0.11450000948335928,destabilizing
+SF3B1,DLG2,0.07726650950587327,destabilizing
+SF3B1,CHST12,0.14098852880207008,destabilizing
+SF3B1,EML5,0.08944635363557042,destabilizing
+SF3B1,TMEM106B,0.10166909390145175,destabilizing
+SF3B1,ZNF521,0.07368127713349826,destabilizing
+SF3B1,NOVA1,0.10675397218414628,destabilizing
+SF3B1,CCNY,0.1022060949541962,destabilizing
+SF3B1,ARIH1,0.06351816072130634,destabilizing
+SF3B1,NCOA2,0.06710841681524657,destabilizing
+SF3B1,CPEB3,0.10749140320705448,destabilizing
+SF3B1,XKR6,0.09959610699183057,destabilizing
+SF3B1,TCF20,0.08941088457010159,destabilizing
+SF3B1,EXOC6B,0.08839355729772218,destabilizing
+SF3B1,MAGI3,0.0869862113545946,destabilizing
+SF3B1,DMD,0.10055205107952908,destabilizing
+SF3B1,MCU,0.07325667257004034,destabilizing
+SF3B1,SSH2,0.07724815477744658,destabilizing
+SF3B1,DOCK3,0.07581842244481322,destabilizing
+SF3B1,HS6ST3,0.11174057883116818,destabilizing
+SF3B1,GTF2IRD1,0.07045447311782654,destabilizing
+SF3B1,FMN2,0.06623172425909518,destabilizing
+SF3B1,ENSG00000228222,0.12408327054475048,destabilizing
+SF3B1,PRKN,0.10545381776944387,destabilizing
+SF3B1,FRMD5,0.07245016913155869,destabilizing
+SF3B1,PPM1E,0.07327117768475361,destabilizing
+SF3B1,SLIT2,0.0986092252541244,destabilizing
+SF3B1,NEGR1,0.0759341242845733,destabilizing
+SF3B1,ENOX1,0.11076302074565175,destabilizing
+SF3B1,GPHN,0.05880829743062761,destabilizing
+SF3B1,NAV3,0.09552839922775985,destabilizing
+SF3B1,TOMM22,0.08037824757317998,destabilizing
+SF3B1,AKAP6,0.06639882474605809,destabilizing
+SF3B1,GRIK2,0.06981773200008301,destabilizing
+SF3B1,LRRC37A3,0.11068393517458999,destabilizing
+SF3B1,MLLT3,0.10799731496100869,destabilizing
+SF3B1,ROBO1,0.07362432543027718,destabilizing
+PRPF8,DOC2B,0.06570902292254747,destabilizing
+PRPF8,FRY,0.08604177192218421,destabilizing
+PRPF8,MACROD2,0.0646321614109586,destabilizing
+PRPF8,EML5,0.08681819723693136,destabilizing
+PRPF8,CENPP,0.20439599123997051,destabilizing
+PRPF8,KCNB2,0.11145328986727453,destabilizing
+PRPF8,DTL,-0.11571567898253325,stabilizing
+PRPF8,PUM2,-0.05285790472233099,stabilizing
+PRPF8,ALK,0.17901592985028997,destabilizing
+PRPF8,CCNT1,0.06372044674531048,destabilizing
+PRPF8,ENAH,-0.06609366780260238,stabilizing
+PRPF8,SIK3,0.08700119764554565,destabilizing
+PRPF8,MCU,0.07097092083072552,destabilizing
+PRPF8,TRIO,-0.062465333380717025,stabilizing
+PRPF8,ENSG00000228222,0.11540116823255833,destabilizing
+PRPF8,SYN3,0.051358714666599595,destabilizing
+PRPF8,RASA2,0.06711263953363913,destabilizing
+PRPF8,WIPF2,0.07378392197356777,destabilizing
+PRPF8,DOCK4,-0.06072081113173316,stabilizing
+PRPF8,KCNQ5,-0.05249171612588564,stabilizing
+PRPF8,MLLT3,0.09722360285912375,destabilizing
+PRPF8,AUTS2,-0.07253888352038833,stabilizing
+SNRNP200,TOX,0.06637811671636658,destabilizing
+SNRNP200,FRY,0.09222970740413282,destabilizing
+SNRNP200,RUNX1T1,0.06325237006794474,destabilizing
+SNRNP200,MACROD2,0.0701798832143161,destabilizing
+SNRNP200,CDK12,0.10696590527025744,destabilizing
+SNRNP200,DLG2,0.06634133950724294,destabilizing
+SNRNP200,CENPP,0.2090647570342755,destabilizing
+SNRNP200,KCNB2,0.10611253047499916,destabilizing
+SNRNP200,DTL,-0.09307223670690094,stabilizing
+SNRNP200,ALK,0.16079774048977222,destabilizing
+SNRNP200,XKR6,0.08694324267719454,destabilizing
+SNRNP200,DMD,0.07708237794405702,destabilizing
+SNRNP200,MCU,0.07005125670227683,destabilizing
+SNRNP200,PHACTR1,0.0656555111541415,destabilizing
+SNRNP200,ENSG00000228222,0.1430018242596071,destabilizing
+SNRNP200,SYN3,0.0510722725523965,destabilizing
+SNRNP200,WIPF2,0.07236908987785046,destabilizing
+SNRNP200,ANKFN1,0.07759653958662881,destabilizing
+SNRNP200,MLLT3,0.09182953247792341,destabilizing
+DDX3X,TMEM106B,0.07736799923383204,destabilizing
+DDX3X,DOCK3,0.08166980446945431,destabilizing
+DDX3X,UNC5C,0.0713110353532504,destabilizing
+DDX5,TRERF1,0.27307210339284865,destabilizing
+DDX5,SORCS1,0.17250816735312668,destabilizing
+DDX5,NCOA1,0.09298617398800227,destabilizing
+DDX5,COPA,0.12899182534750037,destabilizing
+DDX5,FCHSD2,0.15945173101139584,destabilizing
+DDX5,PDE3A,0.2718455191728201,destabilizing
+DDX5,UNC79,0.31210717277548017,destabilizing
+DDX5,DOC2B,0.19923375544835742,destabilizing
+DDX5,TMTC2,0.2816248260323178,destabilizing
+DDX5,KALRN,0.21982061710944292,destabilizing
+DDX5,CHD1,0.14173575995785911,destabilizing
+DDX5,PAK3,0.07753427414827423,destabilizing
+DDX5,UBE2E2,0.10082400120344967,destabilizing
+DDX5,PPARD,0.13312913049166528,destabilizing
+DDX5,TOX,0.06996438593413234,destabilizing
+DDX5,BRAF,0.08209139209718101,destabilizing
+DDX5,RYR2,0.2040242797226361,destabilizing
+DDX5,ZNF609,0.06749673863870845,destabilizing
+DDX5,MTMR7,0.28589752783829775,destabilizing
+DDX5,EIF4E,0.2839263382908393,destabilizing
+DDX5,SOX11,0.12659631576138541,destabilizing
+DDX5,EPB41L4B,0.20744933307261443,destabilizing
+DDX5,CACNA1B,0.20837418156846857,destabilizing
+DDX5,TBC1D5,0.12411665666809905,destabilizing
+DDX5,LRRTM4,0.21212211598054098,destabilizing
+DDX5,SIRPA,0.22406964126351747,destabilizing
+DDX5,PTEN,0.1769285656756917,destabilizing
+DDX5,FRY,0.2680013253547842,destabilizing
+DDX5,MACROD2,0.23849305747438873,destabilizing
+DDX5,FOXN3,0.0933466643309287,destabilizing
+DDX5,SHANK2,0.35973796273422964,destabilizing
+DDX5,CDK12,0.38822563829748996,destabilizing
+DDX5,BMPR1B,0.04992494036845782,destabilizing
+DDX5,RFX7,0.2698057507396226,destabilizing
+DDX5,UBR5,0.14094533457650427,destabilizing
+DDX5,JARID2,0.14212319266924595,destabilizing
+DDX5,MPHOSPH8,0.2360473403973155,destabilizing
+DDX5,DIP2C,0.21517066718052447,destabilizing
+DDX5,ZNF423,0.1253907854434453,destabilizing
+DDX5,UBR3,0.19963495461500425,destabilizing
+DDX5,MGAT5,0.13168709768341053,destabilizing
+DDX5,DLG2,0.17431751100610524,destabilizing
+DDX5,CHST12,0.4398011232711129,destabilizing
+DDX5,EML5,0.278971961334302,destabilizing
+DDX5,CENPP,0.2190463871795585,destabilizing
+DDX5,PSME4,0.2570254391175343,destabilizing
+DDX5,TMEM106B,0.29487069585629144,destabilizing
+DDX5,RABGAP1L,0.05852747439657196,destabilizing
+DDX5,EPHA5,0.22044996172667283,destabilizing
+DDX5,KCNB2,0.27470281648716843,destabilizing
+DDX5,ZNF83,0.20667903827969777,destabilizing
+DDX5,SOX6,0.1666927802273491,destabilizing
+DDX5,ZNF521,0.25144739384756154,destabilizing
+DDX5,PLEKHA5,0.1514978928319219,destabilizing
+DDX5,DTL,0.14352425348069475,destabilizing
+DDX5,NOVA1,0.32102875744153453,destabilizing
+DDX5,CCNY,0.26410535709119987,destabilizing
+DDX5,ARIH1,0.16663754000280032,destabilizing
+DDX5,FAM171B,0.08523249518883531,destabilizing
+DDX5,EPB41L5,0.22261679087011024,destabilizing
+DDX5,GPR158,0.22282663795612473,destabilizing
+DDX5,NCOA2,0.2035048469302737,destabilizing
+DDX5,PRKCB,0.08646133327149158,destabilizing
+DDX5,MARCKS,0.1120015476699468,destabilizing
+DDX5,ALK,0.2412035461498599,destabilizing
+DDX5,ACACA,0.14017864944796288,destabilizing
+DDX5,CTNND2,0.1169406631005538,destabilizing
+DDX5,IFT172,0.27491377834673947,destabilizing
+DDX5,CCNT1,0.16032628844721697,destabilizing
+DDX5,ENAH,0.08409972765056993,destabilizing
+DDX5,DTWD2,0.31830929943125397,destabilizing
+DDX5,SIK3,0.13230849728258404,destabilizing
+DDX5,CPEB3,0.264797030663222,destabilizing
+DDX5,CADM2,0.17139016981872796,destabilizing
+DDX5,XKR6,0.32381822866007076,destabilizing
+DDX5,RMND5A,0.12289215827581886,destabilizing
+DDX5,CADPS,0.12130555640293811,destabilizing
+DDX5,FGF13,0.08029785346034278,destabilizing
+DDX5,TCF20,0.24923084138561785,destabilizing
+DDX5,CDKAL1,0.13523122303917162,destabilizing
+DDX5,DGKI,0.18141396485905636,destabilizing
+DDX5,EXOC6B,0.2877875729050628,destabilizing
+DDX5,MAGI3,0.26297305140448346,destabilizing
+DDX5,SBF2,0.157333318640182,destabilizing
+DDX5,INPP4B,0.2587862069935939,destabilizing
+DDX5,ERC1,0.11617686684648873,destabilizing
+DDX5,PTPRS,0.30808969524785834,destabilizing
+DDX5,CBFA2T2,0.14953509666459935,destabilizing
+DDX5,SPDYE3,0.2478575750348737,destabilizing
+DDX5,TMEM178B,0.12497516570261241,destabilizing
+DDX5,KMT2C,0.09667847157121472,destabilizing
+DDX5,CACNA2D1,0.059092762527177295,destabilizing
+DDX5,DMD,0.3742747672380122,destabilizing
+DDX5,EIF4G3,0.08196722452851474,destabilizing
+DDX5,MCU,0.1547006046410554,destabilizing
+DDX5,SSH2,0.2035448128789825,destabilizing
+DDX5,TCF12,0.05112845526166225,destabilizing
+DDX5,DOCK3,0.30650191292703727,destabilizing
+DDX5,HS6ST3,0.2613114462662903,destabilizing
+DDX5,LPP,0.29802987803558456,destabilizing
+DDX5,STAG1,0.20787299670752193,destabilizing
+DDX5,CAPZA2,0.243929964246517,destabilizing
+DDX5,ADGRL3,0.1304202944881161,destabilizing
+DDX5,PHACTR1,0.09788879979990453,destabilizing
+DDX5,UBE2R2,0.2846462324594982,destabilizing
+DDX5,GTF2IRD1,0.23484854728632995,destabilizing
+DDX5,CCBE1,0.14366192993117377,destabilizing
+DDX5,FTX,0.1138550310201881,destabilizing
+DDX5,JMJD1C,0.08778167825703695,destabilizing
+DDX5,TTC28,0.17876023351661796,destabilizing
+DDX5,SBNO1,0.17007643967462,destabilizing
+DDX5,RIMS2,0.15774934444360783,destabilizing
+DDX5,IGF1R,0.1180567579913155,destabilizing
+DDX5,TRIO,0.13563796210107337,destabilizing
+DDX5,KCND2,0.07214409406982888,destabilizing
+DDX5,BTBD9,0.26557041631220785,destabilizing
+DDX5,CNGB1,0.3066086415355457,destabilizing
+DDX5,FMN2,0.22487382721337848,destabilizing
+DDX5,ENSG00000228222,0.38652233263962454,destabilizing
+DDX5,ATXN1,0.07856746563043412,destabilizing
+DDX5,PRKN,0.33197976553090236,destabilizing
+DDX5,RASA2,0.29656141327617763,destabilizing
+DDX5,PPP1R12B,0.14806114603941808,destabilizing
+DDX5,FRMD4A,0.2059231331731325,destabilizing
+DDX5,CAMK1D,0.09023938364943528,destabilizing
+DDX5,PARD3,0.0916109757125991,destabilizing
+DDX5,SEMA6D,0.21658792244391073,destabilizing
+DDX5,WIPF2,0.2937887406988392,destabilizing
+DDX5,DLEU1,0.30745435674146737,destabilizing
+DDX5,TSHZ2,0.14428110392543997,destabilizing
+DDX5,MED13L,0.16374407109858907,destabilizing
+DDX5,AFF3,0.09438139764378176,destabilizing
+DDX5,KAZN,0.22824674487855257,destabilizing
+DDX5,KANSL1,0.15042597622464454,destabilizing
+DDX5,FRMD5,0.21459959643816431,destabilizing
+DDX5,LINC00174,0.2778819929640136,destabilizing
+DDX5,PPM1E,0.21772889944142987,destabilizing
+DDX5,ARL3,0.1644500888589351,destabilizing
+DDX5,MBD5,0.1945273401832655,destabilizing
+DDX5,ELAVL3,0.2640374552298544,destabilizing
+DDX5,SLIT2,0.32973605587018595,destabilizing
+DDX5,SLC8A1,0.05435532611423526,destabilizing
+DDX5,CLASP1,0.17597858916649814,destabilizing
+DDX5,DOCK4,0.06440872946139961,destabilizing
+DDX5,UNC5C,0.22692316947587005,destabilizing
+DDX5,CACNA2D3,-0.13081774227776952,stabilizing
+DDX5,RC3H1,0.1754676169003483,destabilizing
+DDX5,NEGR1,0.2510492915015511,destabilizing
+DDX5,ENOX1,0.3437084056315184,destabilizing
+DDX5,SCUBE1,0.1964587779051395,destabilizing
+DDX5,GPHN,0.16902756116737247,destabilizing
+DDX5,NAV3,0.27872853756114746,destabilizing
+DDX5,EBF1,0.1120007265067494,destabilizing
+DDX5,TOMM22,0.32225322494309094,destabilizing
+DDX5,ANKFN1,0.07298390559361051,destabilizing
+DDX5,MAGI2,0.14367952641352966,destabilizing
+DDX5,LSAMP,0.19092867733230276,destabilizing
+DDX5,AKAP6,0.22397194472776655,destabilizing
+DDX5,TMED2,0.22483577293108742,destabilizing
+DDX5,ZBTB20,0.2061725394268296,destabilizing
+DDX5,GRIK2,0.24577727304793767,destabilizing
+DDX5,SOX5,0.18679421174006697,destabilizing
+DDX5,LRRC37A3,0.3803354798571381,destabilizing
+DDX5,TMEM132C,0.1234474244078461,destabilizing
+DDX5,EYS,0.21731217061483687,destabilizing
+DDX5,ARID1B,0.17608511812896577,destabilizing
+DDX5,PRKCE,0.20256629744378077,destabilizing
+DDX5,RBFOX1,-0.17557933393274616,stabilizing
+DDX5,SDK1,0.15488943455164528,destabilizing
+DDX5,NRG1,0.09693093234992489,destabilizing
+DDX5,MLLT3,0.3912535512736006,destabilizing
+DDX5,AUTS2,0.05793002509954359,destabilizing
+DDX5,FMN1,0.12222533333197573,destabilizing
+DDX5,ADGRB3,0.1489719584511745,destabilizing
+DDX5,ROBO1,0.23433724737954525,destabilizing
+DDX5,SYPL1,0.14226196136782823,destabilizing
+DDX5,PTPRD,0.222634257403466,destabilizing
+DDX5,FAM155A,0.2521126470833999,destabilizing
+DDX5,LARP1B,0.2569534881645491,destabilizing
+DDX6,TRERF1,0.10961212305207584,destabilizing
+DDX6,SORCS1,0.0760693699385343,destabilizing
+DDX6,PDE3A,0.12050185129416244,destabilizing
+DDX6,UNC79,0.10230557457139607,destabilizing
+DDX6,DOC2B,0.09950873605587714,destabilizing
+DDX6,TMTC2,0.09478524667202759,destabilizing
+DDX6,KALRN,0.10457928810820014,destabilizing
+DDX6,MTMR7,0.10159503070896385,destabilizing
+DDX6,EIF4E,0.11360921594282586,destabilizing
+DDX6,EPB41L4B,0.07533729336123089,destabilizing
+DDX6,CACNA1B,0.09329024367730383,destabilizing
+DDX6,LRRTM4,0.09556451004896184,destabilizing
+DDX6,FRY,0.10751467838582367,destabilizing
+DDX6,MACROD2,0.09956959366361845,destabilizing
+DDX6,SHANK2,0.15831791882713064,destabilizing
+DDX6,CDK12,0.14500456331704506,destabilizing
+DDX6,MPHOSPH8,0.07680144468006699,destabilizing
+DDX6,DLG2,0.07520473696921783,destabilizing
+DDX6,CHST12,0.21450591826415707,destabilizing
+DDX6,EML5,0.1061462525826546,destabilizing
+DDX6,CENPP,0.12798815416474635,destabilizing
+DDX6,PSME4,0.07735628396545864,destabilizing
+DDX6,TMEM106B,0.07419634901702021,destabilizing
+DDX6,EPHA5,0.08184597689210465,destabilizing
+DDX6,ZNF83,0.07915828977845445,destabilizing
+DDX6,SOX6,0.056760328714783176,destabilizing
+DDX6,PLEKHA5,0.06660746004180071,destabilizing
+DDX6,NOVA1,0.10095220708309081,destabilizing
+DDX6,CCNY,0.09966775891643019,destabilizing
+DDX6,ARIH1,0.0679706240392942,destabilizing
+DDX6,EPB41L5,0.06741149942667353,destabilizing
+DDX6,GPR158,0.08397852082805136,destabilizing
+DDX6,NCOA2,0.08471887999736341,destabilizing
+DDX6,ALK,0.10345276998142873,destabilizing
+DDX6,IFT172,0.08800691907954251,destabilizing
+DDX6,CCNT1,0.05463003430232756,destabilizing
+DDX6,SIK3,0.07777286203712841,destabilizing
+DDX6,CADM2,0.06327273802859025,destabilizing
+DDX6,XKR6,0.12294470725465792,destabilizing
+DDX6,EXOC6B,0.11605070388703818,destabilizing
+DDX6,MAGI3,0.07421782658635681,destabilizing
+DDX6,SBF2,0.0689848517841201,destabilizing
+DDX6,INPP4B,0.09411483546137384,destabilizing
+DDX6,SPDYE3,0.07664129933513601,destabilizing
+DDX6,DMD,0.15196679098408386,destabilizing
+DDX6,MCU,0.07447807964676492,destabilizing
+DDX6,SSH2,0.06961768359134184,destabilizing
+DDX6,DOCK3,0.1403082414412366,destabilizing
+DDX6,HS6ST3,0.12928011961740157,destabilizing
+DDX6,LPP,0.09616941637666356,destabilizing
+DDX6,STAG1,0.06831444651079822,destabilizing
+DDX6,CAPZA2,0.08035821652891967,destabilizing
+DDX6,ADGRL3,0.06119420223710417,destabilizing
+DDX6,UBE2R2,0.09832848453393137,destabilizing
+DDX6,GTF2IRD1,0.0857428238849828,destabilizing
+DDX6,SBNO1,0.07308058108480465,destabilizing
+DDX6,BTBD9,0.08564014240077598,destabilizing
+DDX6,CNGB1,0.09866608229654054,destabilizing
+DDX6,FMN2,0.08106032812343908,destabilizing
+DDX6,ENSG00000228222,0.15660562357808874,destabilizing
+DDX6,PRKN,0.1549563870741409,destabilizing
+DDX6,RASA2,0.09873072440819645,destabilizing
+DDX6,FRMD4A,0.08154878660105881,destabilizing
+DDX6,SEMA6D,0.06166600756056368,destabilizing
+DDX6,WIPF2,0.09389998631005289,destabilizing
+DDX6,KAZN,0.07982404046213346,destabilizing
+DDX6,FRMD5,0.0842687512497959,destabilizing
+DDX6,LINC00174,0.10296222382037773,destabilizing
+DDX6,PPM1E,0.1013677084024496,destabilizing
+DDX6,ARL3,0.05877417239451922,destabilizing
+DDX6,MBD5,0.07458502840973232,destabilizing
+DDX6,ELAVL3,0.11838928414234048,destabilizing
+DDX6,SLIT2,0.11955604620421942,destabilizing
+DDX6,UNC5C,0.07426807922531646,destabilizing
+DDX6,CACNA2D3,-0.05042856656723013,stabilizing
+DDX6,ENOX1,0.1692512212166231,destabilizing
+DDX6,GPHN,0.06547466385333325,destabilizing
+DDX6,NAV3,0.10250784136098155,destabilizing
+DDX6,TOMM22,0.09562135991284415,destabilizing
+DDX6,MAGI2,0.06300326715381356,destabilizing
+DDX6,AKAP6,0.0856110763624479,destabilizing
+DDX6,ZBTB20,0.09407453101869635,destabilizing
+DDX6,GRIK2,0.08644519962565668,destabilizing
+DDX6,LRRC37A3,0.13213749893439777,destabilizing
+DDX6,EYS,0.08325507578979317,destabilizing
+DDX6,RBFOX1,-0.07530566935665506,stabilizing
+DDX6,MLLT3,0.1600181389773704,destabilizing
+DDX6,ADGRB3,0.06229846414202425,destabilizing
+DDX6,ROBO1,0.09259121738360972,destabilizing
+DDX6,PTPRD,0.07436681018502286,destabilizing
+DDX6,LARP1B,0.0664485724191172,destabilizing
+DDX17,TRERF1,0.17936595825103255,destabilizing
+DDX17,SORCS1,0.10308115659859111,destabilizing
+DDX17,FCHSD2,0.07054222012220379,destabilizing
+DDX17,PDE3A,0.16882171535565693,destabilizing
+DDX17,UNC79,0.16493762169560333,destabilizing
+DDX17,DOC2B,0.12112089361206463,destabilizing
+DDX17,TMTC2,0.14609176323464415,destabilizing
+DDX17,KALRN,0.10217418516785014,destabilizing
+DDX17,CHD1,0.06927374809501531,destabilizing
+DDX17,UBE2E2,0.06019056785649654,destabilizing
+DDX17,PPARD,0.09282650545581032,destabilizing
+DDX17,TOX,0.10378023331547513,destabilizing
+DDX17,RYR2,0.1616463995057224,destabilizing
+DDX17,MTMR7,0.14988395287880169,destabilizing
+DDX17,EIF4E,0.1550294395327502,destabilizing
+DDX17,EPB41L4B,0.09774479345227437,destabilizing
+DDX17,CACNA1B,0.07613942988972285,destabilizing
+DDX17,LRRTM4,0.11118739007744648,destabilizing
+DDX17,SIRPA,0.16614052127412549,destabilizing
+DDX17,PTEN,0.10893512211481732,destabilizing
+DDX17,FRY,0.17009668357217625,destabilizing
+DDX17,MACROD2,0.14866437236015495,destabilizing
+DDX17,SHANK2,0.2546748578169595,destabilizing
+DDX17,CDK12,0.16479459361240076,destabilizing
+DDX17,BMPR1B,0.05666031805012449,destabilizing
+DDX17,RFX7,0.17188489318412706,destabilizing
+DDX17,UBR5,0.0763292007654897,destabilizing
+DDX17,JARID2,0.06797956020232837,destabilizing
+DDX17,MPHOSPH8,0.0903560960816566,destabilizing
+DDX17,DIP2C,0.12916859200242795,destabilizing
+DDX17,UBR3,0.15245728837226505,destabilizing
+DDX17,MGAT5,0.05463150745475847,destabilizing
+DDX17,DLG2,0.11056670242384688,destabilizing
+DDX17,CHST12,0.20045817331162036,destabilizing
+DDX17,EML5,0.15867278945720392,destabilizing
+DDX17,CENPP,0.20842464201755967,destabilizing
+DDX17,PSME4,0.14752485868981055,destabilizing
+DDX17,TMEM106B,0.17452493459820634,destabilizing
+DDX17,EPHA5,0.10565479531581318,destabilizing
+DDX17,KCNB2,0.13563703281604847,destabilizing
+DDX17,ZNF83,0.10368915052026695,destabilizing
+DDX17,ZNF521,0.08394102634313043,destabilizing
+DDX17,PLEKHA5,0.09749301263278354,destabilizing
+DDX17,NOVA1,0.18508831993133076,destabilizing
+DDX17,CCNY,0.17852808631180758,destabilizing
+DDX17,ARIH1,0.13579720758074756,destabilizing
+DDX17,EPB41L5,0.08401664004788424,destabilizing
+DDX17,GPR158,0.16278926756376574,destabilizing
+DDX17,NCOA2,0.10510632199264384,destabilizing
+DDX17,ALK,0.16050649423995308,destabilizing
+DDX17,ACACA,0.07166132639677969,destabilizing
+DDX17,ARHGAP26,0.0690600283288032,destabilizing
+DDX17,IFT172,0.10459249516493377,destabilizing
+DDX17,CCNT1,0.055924608990693445,destabilizing
+DDX17,DTWD2,0.1943897897049406,destabilizing
+DDX17,SIK3,0.1488111369958518,destabilizing
+DDX17,CPEB3,0.15324257650933956,destabilizing
+DDX17,XKR6,0.16630594467371126,destabilizing
+DDX17,CADPS,0.0880586074792473,destabilizing
+DDX17,FGF13,0.06383926792171567,destabilizing
+DDX17,TCF20,0.17270841339201592,destabilizing
+DDX17,CDKAL1,0.12852094315632237,destabilizing
+DDX17,DGKI,0.10607684805166878,destabilizing
+DDX17,EXOC6B,0.17099261450946837,destabilizing
+DDX17,MAGI3,0.1368058468067738,destabilizing
+DDX17,SBF2,0.06393444370332695,destabilizing
+DDX17,INPP4B,0.13769173103516424,destabilizing
+DDX17,PTPRS,0.17913841420490795,destabilizing
+DDX17,CBFA2T2,0.06500967536186206,destabilizing
+DDX17,SPDYE3,0.12311643891421982,destabilizing
+DDX17,TMEM178B,0.06589138397980801,destabilizing
+DDX17,DMD,0.21943645524337588,destabilizing
+DDX17,MCU,0.12732518742991847,destabilizing
+DDX17,SSH2,0.10866160479856893,destabilizing
+DDX17,DOCK3,0.14610721134709712,destabilizing
+DDX17,HS6ST3,0.12987889389486346,destabilizing
+DDX17,LPP,0.1685769022895398,destabilizing
+DDX17,STAG1,0.12901529531810635,destabilizing
+DDX17,CAPZA2,0.10446325440025059,destabilizing
+DDX17,PHACTR1,0.07753789938384921,destabilizing
+DDX17,UBE2R2,0.1269855576130634,destabilizing
+DDX17,GTF2IRD1,0.12622778014901873,destabilizing
+DDX17,CCBE1,0.07140453270851768,destabilizing
+DDX17,VAPA,-0.056383447981935716,stabilizing
+DDX17,TTC28,0.1057035948363843,destabilizing
+DDX17,RIMS2,0.08074639243405862,destabilizing
+DDX17,BTBD9,0.13736069406594534,destabilizing
+DDX17,CNGB1,0.1582360280554781,destabilizing
+DDX17,FMN2,0.1042794273182335,destabilizing
+DDX17,ENSG00000228222,0.24683579011156892,destabilizing
+DDX17,PRKN,0.2016621595875676,destabilizing
+DDX17,RASA2,0.09903955795305161,destabilizing
+DDX17,FRMD4A,0.0838914543173216,destabilizing
+DDX17,CAMK1D,0.07687388285775001,destabilizing
+DDX17,SEMA6D,0.106588723645623,destabilizing
+DDX17,WIPF2,0.10862684831791808,destabilizing
+DDX17,DLEU1,0.1716035241120241,destabilizing
+DDX17,TSHZ2,0.0888190508580098,destabilizing
+DDX17,MED13L,0.07153934988823675,destabilizing
+DDX17,KAZN,0.1326392754252293,destabilizing
+DDX17,FRMD5,0.16127801172883488,destabilizing
+DDX17,LINC00174,0.08194181041297584,destabilizing
+DDX17,PPM1E,0.13195395842597163,destabilizing
+DDX17,MBD5,0.10887688848928663,destabilizing
+DDX17,ELAVL3,0.09194783933255775,destabilizing
+DDX17,SLIT2,0.18848575013132574,destabilizing
+DDX17,CLASP1,0.07612460138658354,destabilizing
+DDX17,UNC5C,0.14178308024152902,destabilizing
+DDX17,CACNA2D3,-0.05855642518588489,stabilizing
+DDX17,RC3H1,0.07830043555710606,destabilizing
+DDX17,NEGR1,0.13830217729754707,destabilizing
+DDX17,ENOX1,0.22133988067247123,destabilizing
+DDX17,SCUBE1,0.06155290313885961,destabilizing
+DDX17,GPHN,0.1012046230562703,destabilizing
+DDX17,NAV3,0.14036861244901494,destabilizing
+DDX17,EBF1,0.05775043615716589,destabilizing
+DDX17,TOMM22,0.11829509463499234,destabilizing
+DDX17,MBNL2,0.07053797149460053,destabilizing
+DDX17,ANKFN1,0.06265817770525493,destabilizing
+DDX17,MAGI2,0.05336784858729597,destabilizing
+DDX17,AKAP6,0.11300577188088569,destabilizing
+DDX17,ZBTB20,0.11545663100743661,destabilizing
+DDX17,GRIK2,0.12874739059413712,destabilizing
+DDX17,SOX5,0.09479237090797465,destabilizing
+DDX17,LRRC37A3,0.17590376798971125,destabilizing
+DDX17,EYS,0.07527709887646059,destabilizing
+DDX17,ARID1B,0.09025038023247274,destabilizing
+DDX17,PRKCE,0.09590127508711174,destabilizing
+DDX17,RBFOX1,-0.07345862824114138,stabilizing
+DDX17,MLLT3,0.16134862407905076,destabilizing
+DDX17,FMN1,0.061144548329201694,destabilizing
+DDX17,ADGRB3,0.08021678285684526,destabilizing
+DDX17,ROBO1,0.14711085567719642,destabilizing
+DDX17,SYPL1,0.06890204108704623,destabilizing
+DDX17,PTPRD,0.10187326855874194,destabilizing
+DDX17,FAM155A,0.1629114729022714,destabilizing
+DDX17,LARP1B,0.12344355060290368,destabilizing
+DHX9,UNC79,0.09191554061833354,destabilizing
+DHX9,DOC2B,0.06919754104164517,destabilizing
+DHX9,FRY,0.11575106847966275,destabilizing
+DHX9,MACROD2,0.11051121862665687,destabilizing
+DHX9,CDK12,0.11882101240910968,destabilizing
+DHX9,EML5,0.10119926525019203,destabilizing
+DHX9,CENPP,0.15201391384513893,destabilizing
+DHX9,PSME4,0.08250121805025136,destabilizing
+DHX9,KCNB2,0.12475964303888186,destabilizing
+DHX9,ZNF83,0.07010344083721703,destabilizing
+DHX9,SOX6,0.07246844046024502,destabilizing
+DHX9,CCNY,0.08467713329665147,destabilizing
+DHX9,GPR158,0.08341699460921523,destabilizing
+DHX9,ALK,0.12346339726200561,destabilizing
+DHX9,DTWD2,0.1781694082222151,destabilizing
+DHX9,CPEB3,0.12533099684414686,destabilizing
+DHX9,XKR6,0.08924058562981516,destabilizing
+DHX9,TCF20,0.08663346315078002,destabilizing
+DHX9,EXOC6B,0.10414529727346354,destabilizing
+DHX9,MAGI3,0.09965081834798013,destabilizing
+DHX9,DMD,0.10173510712400904,destabilizing
+DHX9,DOCK3,0.08873862352520377,destabilizing
+DHX9,ENSG00000228222,0.116268958585847,destabilizing
+DHX9,RASA2,0.08232435798178783,destabilizing
+DHX9,WIPF2,0.0867678285323384,destabilizing
+DHX9,LINC00174,0.06163382848508832,destabilizing
+DHX9,MBD5,0.07299690013917047,destabilizing
+DHX9,ELAVL3,0.07546294460019073,destabilizing
+DHX9,UNC5C,0.06785036016687032,destabilizing
+DHX9,NEGR1,0.07732765984217034,destabilizing
+DHX9,ENOX1,0.10850884440502559,destabilizing
+DHX9,LRRC37A3,0.0954634062720427,destabilizing
+DHX9,MLLT3,0.13711772850320053,destabilizing
+DHX9,SYPL1,0.05465111089545645,destabilizing
+EIF4E,EIF4E,-0.2749728667248344,stabilizing
+LARP4,FRY,0.08692430285365423,destabilizing
+LARP4,SHANK2,0.1134728873574073,destabilizing
+LARP4,KCNB2,0.11041326652984523,destabilizing
+LARP4,MAGI3,0.07405299068730258,destabilizing
+LARP4,CNGB1,0.09139342638378636,destabilizing
+LARP4,RASA2,0.06723982409218594,destabilizing
+LARP4,FRMD5,0.06455665355849163,destabilizing
+LARP4,MLLT3,0.08070562754407916,destabilizing
+LARP6,UNC79,0.09147200189425977,destabilizing
+LARP6,MACROD2,0.06444643548958412,destabilizing
+LARP6,CPEB3,0.11121372148466373,destabilizing
+LARP6,UNC5C,0.06951542915037964,destabilizing
+LARP6,NEGR1,0.086344920920756,destabilizing
+LARP7,TRERF1,0.1304268537467488,destabilizing
+LARP7,SORCS1,0.08409381894512227,destabilizing
+LARP7,UNC79,0.14435760421108743,destabilizing
+LARP7,DOC2B,0.0728797633193181,destabilizing
+LARP7,TMTC2,0.10747112385824346,destabilizing
+LARP7,KALRN,0.0787214088869397,destabilizing
+LARP7,CHD1,0.07550834637138343,destabilizing
+LARP7,MTMR7,0.1105062491625736,destabilizing
+LARP7,EIF4E,0.1366798727303677,destabilizing
+LARP7,EPB41L4B,0.07517236437029509,destabilizing
+LARP7,CACNA1B,0.07057161016672146,destabilizing
+LARP7,TBC1D5,0.054692358944594614,destabilizing
+LARP7,LRRTM4,0.07073515413106249,destabilizing
+LARP7,PTEN,0.0907335233271222,destabilizing
+LARP7,FRY,0.12717101676781628,destabilizing
+LARP7,MACROD2,0.13001301656066572,destabilizing
+LARP7,SHANK2,0.15224604532139374,destabilizing
+LARP7,CDK12,0.17904693362014737,destabilizing
+LARP7,RFX7,0.10685207301917322,destabilizing
+LARP7,JARID2,0.05529923349633873,destabilizing
+LARP7,MPHOSPH8,0.11559731383571954,destabilizing
+LARP7,DIP2C,0.08878270688956136,destabilizing
+LARP7,UBR3,0.07385656285866202,destabilizing
+LARP7,DLG2,0.08479961676012042,destabilizing
+LARP7,CHST12,0.21030152882708317,destabilizing
+LARP7,EML5,0.1413186198297676,destabilizing
+LARP7,CENPP,0.12048704862253282,destabilizing
+LARP7,PSME4,0.08965230986717772,destabilizing
+LARP7,TMEM106B,0.11489503171447879,destabilizing
+LARP7,EPHA5,0.09194728578324152,destabilizing
+LARP7,KCNB2,0.13053376323638372,destabilizing
+LARP7,ZNF83,0.07489245585863463,destabilizing
+LARP7,SOX6,0.0784902169318921,destabilizing
+LARP7,ZNF521,0.08324142110950906,destabilizing
+LARP7,NOVA1,0.12317167221701783,destabilizing
+LARP7,CCNY,0.10296886207212852,destabilizing
+LARP7,ARIH1,0.0919009142788519,destabilizing
+LARP7,EPB41L5,0.08561854926279999,destabilizing
+LARP7,GPR158,0.12274766992122242,destabilizing
+LARP7,NCOA2,0.10420629522695495,destabilizing
+LARP7,ALK,0.13674388145016764,destabilizing
+LARP7,ACACA,0.0703217083762276,destabilizing
+LARP7,IFT172,0.10516870873425979,destabilizing
+LARP7,CCNT1,0.07035481664974552,destabilizing
+LARP7,SIK3,0.07584177377399585,destabilizing
+LARP7,CPEB3,0.1280774978796475,destabilizing
+LARP7,CADM2,0.05938079250316794,destabilizing
+LARP7,XKR6,0.11972302920399039,destabilizing
+LARP7,RMND5A,0.05350934965573967,destabilizing
+LARP7,CADPS,0.07338911533722764,destabilizing
+LARP7,TCF20,0.10864807635231184,destabilizing
+LARP7,CDKAL1,0.08435424041855993,destabilizing
+LARP7,DGKI,0.10389430750200315,destabilizing
+LARP7,EXOC6B,0.12813478653187876,destabilizing
+LARP7,MAGI3,0.10612353453440641,destabilizing
+LARP7,SBF2,0.059166726297837896,destabilizing
+LARP7,INPP4B,0.12003866217302185,destabilizing
+LARP7,PTPRS,0.13757480074535924,destabilizing
+LARP7,CBFA2T2,0.061678323595797196,destabilizing
+LARP7,SPDYE3,0.0986776444706056,destabilizing
+LARP7,DMD,0.1858745307836745,destabilizing
+LARP7,MCU,0.07903560387914105,destabilizing
+LARP7,SSH2,0.09422693465712433,destabilizing
+LARP7,DOCK3,0.1273890593142212,destabilizing
+LARP7,HS6ST3,0.12365796732907265,destabilizing
+LARP7,LPP,0.09991652728723464,destabilizing
+LARP7,CAPZA2,0.10111862841865008,destabilizing
+LARP7,ADGRL3,0.06379988234043808,destabilizing
+LARP7,UBE2R2,0.08350441075643511,destabilizing
+LARP7,GTF2IRD1,0.11062268904330541,destabilizing
+LARP7,CCBE1,0.060275670351042906,destabilizing
+LARP7,TTC28,0.07641460664775304,destabilizing
+LARP7,RIMS2,0.07131480730216606,destabilizing
+LARP7,TRIO,0.057014193824023965,destabilizing
+LARP7,BTBD9,0.10221103843959212,destabilizing
+LARP7,CNGB1,0.11862023071555593,destabilizing
+LARP7,FMN2,0.08877065727914477,destabilizing
+LARP7,ENSG00000228222,0.17464377623186103,destabilizing
+LARP7,PRKN,0.14826981586079513,destabilizing
+LARP7,RASA2,0.11298407378823387,destabilizing
+LARP7,PPP1R12B,0.08640743538385665,destabilizing
+LARP7,FRMD4A,0.09446710108786358,destabilizing
+LARP7,SEMA6D,0.08187935857073794,destabilizing
+LARP7,WIPF2,0.122297327408666,destabilizing
+LARP7,DLEU1,0.15543729624167385,destabilizing
+LARP7,TSHZ2,0.06985040671942931,destabilizing
+LARP7,MED13L,0.06500540402445609,destabilizing
+LARP7,KAZN,0.08954183476917371,destabilizing
+LARP7,FRMD5,0.10044790895071748,destabilizing
+LARP7,LINC00174,0.09979043138869115,destabilizing
+LARP7,PPM1E,0.10822308463921247,destabilizing
+LARP7,ARL3,0.07019959463379204,destabilizing
+LARP7,MBD5,0.07851786485765377,destabilizing
+LARP7,ELAVL3,0.10852978648464556,destabilizing
+LARP7,SLIT2,0.16101022706234228,destabilizing
+LARP7,CLASP1,0.0770038955570518,destabilizing
+LARP7,UNC5C,0.10931414382085165,destabilizing
+LARP7,CACNA2D3,-0.053741221836578514,stabilizing
+LARP7,RC3H1,0.07569954816406939,destabilizing
+LARP7,NEGR1,0.09329597201540003,destabilizing
+LARP7,ENOX1,0.17178027775460525,destabilizing
+LARP7,SCUBE1,0.08599549738120586,destabilizing
+LARP7,GPHN,0.06363457942051541,destabilizing
+LARP7,NAV3,0.14092038713103158,destabilizing
+LARP7,TOMM22,0.13759048182606634,destabilizing
+LARP7,LSAMP,0.07403568434254335,destabilizing
+LARP7,AKAP6,0.0781729333998656,destabilizing
+LARP7,TMED2,0.07776054800602974,destabilizing
+LARP7,ZBTB20,0.10915393035034496,destabilizing
+LARP7,GRIK2,0.09503804728347134,destabilizing
+LARP7,LRRC37A3,0.1261702505355187,destabilizing
+LARP7,EYS,0.07049768758354732,destabilizing
+LARP7,ARID1B,0.06471003504068587,destabilizing
+LARP7,RBFOX1,-0.07282070514951568,stabilizing
+LARP7,SDK1,0.062475203958762715,destabilizing
+LARP7,MLLT3,0.16368020242242037,destabilizing
+LARP7,ADGRB3,0.05955683457887009,destabilizing
+LARP7,ROBO1,0.08857126528428709,destabilizing
+LARP7,SYPL1,0.057094834384395256,destabilizing
+LARP7,PTPRD,0.10364863439727534,destabilizing
+LARP7,FAM155A,0.11518123393442459,destabilizing
+LARP7,LARP1B,0.08763859234510028,destabilizing
+NCL,TRERF1,0.17295130003785603,destabilizing
+NCL,SORCS1,0.12515659168204318,destabilizing
+NCL,NCOA1,0.06522525857818863,destabilizing
+NCL,FCHSD2,0.08286760865120792,destabilizing
+NCL,PDE3A,0.14584243829276178,destabilizing
+NCL,UNC79,0.1813368014878177,destabilizing
+NCL,DOC2B,0.13128354864578562,destabilizing
+NCL,TMTC2,0.19296636663490135,destabilizing
+NCL,KALRN,0.09081009838692246,destabilizing
+NCL,CHD1,0.09676646185671484,destabilizing
+NCL,UBE2E2,0.07112370790396486,destabilizing
+NCL,PPARD,0.10870852700503598,destabilizing
+NCL,TOX,0.08471782445372558,destabilizing
+NCL,BRAF,0.05515929056290525,destabilizing
+NCL,RYR2,0.16318308338338863,destabilizing
+NCL,MTMR7,0.17594089003456972,destabilizing
+NCL,EIF4E,0.1502490546167142,destabilizing
+NCL,SOX11,0.06313250731376818,destabilizing
+NCL,EPB41L4B,0.09251981661364699,destabilizing
+NCL,CACNA1B,0.10329593887048955,destabilizing
+NCL,LRRTM4,0.11225906604322994,destabilizing
+NCL,PTEN,0.10495095430473139,destabilizing
+NCL,FRY,0.17971624637741082,destabilizing
+NCL,MACROD2,0.1771108322526778,destabilizing
+NCL,SHANK2,0.2266350176030162,destabilizing
+NCL,CDK12,0.20483138507065612,destabilizing
+NCL,RFX7,0.1680033667460092,destabilizing
+NCL,JARID2,0.08350741481660005,destabilizing
+NCL,MPHOSPH8,0.11264505565012586,destabilizing
+NCL,DIP2C,0.09349090908696382,destabilizing
+NCL,UBR3,0.11669690664176824,destabilizing
+NCL,DLG2,0.09970667675278591,destabilizing
+NCL,CHST12,0.21742345838508215,destabilizing
+NCL,EML5,0.17210983572886746,destabilizing
+NCL,CENPP,0.2712400241837624,destabilizing
+NCL,PSME4,0.14659751239030516,destabilizing
+NCL,TMEM106B,0.16030745897462267,destabilizing
+NCL,EPHA5,0.14256175422070774,destabilizing
+NCL,KCNB2,0.19121522230640164,destabilizing
+NCL,ZNF83,0.11610776186461265,destabilizing
+NCL,SOX6,0.0877033490883364,destabilizing
+NCL,ZNF521,0.136160501877904,destabilizing
+NCL,PLEKHA5,0.06823351524726548,destabilizing
+NCL,NOVA1,0.2139847941174402,destabilizing
+NCL,CCNY,0.15447632615354545,destabilizing
+NCL,ARIH1,0.14753646733794548,destabilizing
+NCL,EPB41L5,0.0967242696361523,destabilizing
+NCL,GPR158,0.16230224651510047,destabilizing
+NCL,NCOA2,0.10824828282937002,destabilizing
+NCL,ALK,0.21846216284353623,destabilizing
+NCL,ACACA,0.05776673165662883,destabilizing
+NCL,IFT172,0.14828222376817105,destabilizing
+NCL,CCNT1,0.08398154709940314,destabilizing
+NCL,DTWD2,0.22282929775794644,destabilizing
+NCL,SIK3,0.1572473690541032,destabilizing
+NCL,CPEB3,0.15269113681731533,destabilizing
+NCL,CADM2,0.07801202547297531,destabilizing
+NCL,XKR6,0.1892426710953384,destabilizing
+NCL,CADPS,0.10264680595097407,destabilizing
+NCL,TCF20,0.14690075511643416,destabilizing
+NCL,CDKAL1,0.11751022165306528,destabilizing
+NCL,DGKI,0.12129381867518306,destabilizing
+NCL,EXOC6B,0.20589974050678506,destabilizing
+NCL,MAGI3,0.191470174617459,destabilizing
+NCL,SBF2,0.08296610016720982,destabilizing
+NCL,INPP4B,0.1351813995219388,destabilizing
+NCL,PTPRS,0.22510959707931247,destabilizing
+NCL,CBFA2T2,0.07128657898966052,destabilizing
+NCL,SPDYE3,0.1166695809167942,destabilizing
+NCL,TMEM178B,0.0877328311435933,destabilizing
+NCL,DMD,0.2219387421720987,destabilizing
+NCL,MCU,0.1475888030903155,destabilizing
+NCL,SSH2,0.12431662716921921,destabilizing
+NCL,DOCK3,0.1924078896965684,destabilizing
+NCL,HS6ST3,0.097515551489632,destabilizing
+NCL,LPP,0.16474283976400508,destabilizing
+NCL,STAG1,0.10908957413060434,destabilizing
+NCL,CAPZA2,0.1436551751333912,destabilizing
+NCL,ADGRL3,0.08063166599976616,destabilizing
+NCL,PHACTR1,0.07103840538099306,destabilizing
+NCL,UBE2R2,0.15399404892400978,destabilizing
+NCL,GTF2IRD1,0.15291445374610663,destabilizing
+NCL,TTC28,0.13782411159070687,destabilizing
+NCL,SBNO1,0.07951137593902632,destabilizing
+NCL,RIMS2,0.0818844372294851,destabilizing
+NCL,BTBD9,0.1442574608662313,destabilizing
+NCL,CNGB1,0.13423802630034803,destabilizing
+NCL,FMN2,0.11308358938745779,destabilizing
+NCL,ENSG00000228222,0.24229867387917747,destabilizing
+NCL,SYN3,0.06475117375202234,destabilizing
+NCL,PRKN,0.18934797785187343,destabilizing
+NCL,RASA2,0.151456754835021,destabilizing
+NCL,FRMD4A,0.10485760030415797,destabilizing
+NCL,SEMA6D,0.1279765290568121,destabilizing
+NCL,WIPF2,0.1414369218879598,destabilizing
+NCL,DLEU1,0.18718031882813133,destabilizing
+NCL,TSHZ2,0.1034341036311312,destabilizing
+NCL,MED13L,0.06531207757434841,destabilizing
+NCL,KAZN,0.11800722572861366,destabilizing
+NCL,KANSL1,0.09176428086911084,destabilizing
+NCL,FRMD5,0.1322545561802574,destabilizing
+NCL,LINC00174,0.11679534668198455,destabilizing
+NCL,PPM1E,0.11880508884334536,destabilizing
+NCL,ARL3,0.1222710005518293,destabilizing
+NCL,MBD5,0.11668242756609172,destabilizing
+NCL,ELAVL3,0.13988418595868576,destabilizing
+NCL,SLIT2,0.17633244977149196,destabilizing
+NCL,CLASP1,0.0825476380609461,destabilizing
+NCL,UNC5C,0.1487496721248927,destabilizing
+NCL,CACNA2D3,-0.07090396563059786,stabilizing
+NCL,RC3H1,0.07261565160927812,destabilizing
+NCL,NEGR1,0.20711537651199052,destabilizing
+NCL,ENOX1,0.19592029103025546,destabilizing
+NCL,SCUBE1,0.07133735169252033,destabilizing
+NCL,GPHN,0.0981093913045824,destabilizing
+NCL,NAV3,0.13995655071316052,destabilizing
+NCL,TOMM22,0.16460591044302086,destabilizing
+NCL,ANKFN1,0.05485668548540059,destabilizing
+NCL,MAGI2,0.07442787206408727,destabilizing
+NCL,LSAMP,0.07968432960785655,destabilizing
+NCL,AKAP6,0.12876379300379961,destabilizing
+NCL,ZBTB20,0.14335283677267202,destabilizing
+NCL,GRIK2,0.1174515338477924,destabilizing
+NCL,LRRC37A3,0.1734252190755852,destabilizing
+NCL,EYS,0.10877390478361612,destabilizing
+NCL,ARID1B,0.10013054732649342,destabilizing
+NCL,PRKCE,0.08076254796137122,destabilizing
+NCL,RBFOX1,-0.08715430061020525,stabilizing
+NCL,SDK1,0.07372025352422401,destabilizing
+NCL,MLLT3,0.21113029236467254,destabilizing
+NCL,ADGRB3,0.09786999959527796,destabilizing
+NCL,ROBO1,0.13326793347037547,destabilizing
+NCL,SYPL1,0.07748282585611242,destabilizing
+NCL,PTPRD,0.10972712363783592,destabilizing
+NCL,FAM155A,0.1642476432637018,destabilizing
+NCL,LARP1B,0.12052804855013612,destabilizing
+NPM1,TRERF1,0.11922087766088955,destabilizing
+NPM1,SORCS1,0.07102730454192212,destabilizing
+NPM1,PDE3A,0.1417869697251611,destabilizing
+NPM1,UNC79,0.1441477490640653,destabilizing
+NPM1,DOC2B,0.10111361999026651,destabilizing
+NPM1,TMTC2,0.12997736614346506,destabilizing
+NPM1,MTMR7,0.0900667835796975,destabilizing
+NPM1,EIF4E,0.11175321439286173,destabilizing
+NPM1,CACNA1B,0.059896246669046055,destabilizing
+NPM1,SIRPA,0.11147384291712142,destabilizing
+NPM1,FRY,0.13163434912087554,destabilizing
+NPM1,MACROD2,0.09875324617551068,destabilizing
+NPM1,SHANK2,0.1440562833276198,destabilizing
+NPM1,CDK12,0.12542519338840635,destabilizing
+NPM1,RFX7,0.12782362276571568,destabilizing
+NPM1,MPHOSPH8,0.1030555350738003,destabilizing
+NPM1,DIP2C,0.10586625927774866,destabilizing
+NPM1,UBR3,0.07728085894028068,destabilizing
+NPM1,MGAT5,0.0546372715548766,destabilizing
+NPM1,DLG2,0.09337976478053026,destabilizing
+NPM1,CHST12,0.16644170593236704,destabilizing
+NPM1,EML5,0.11629719433640176,destabilizing
+NPM1,CENPP,0.11969441120131519,destabilizing
+NPM1,PSME4,0.09778655240702074,destabilizing
+NPM1,TMEM106B,0.138856061193793,destabilizing
+NPM1,EPHA5,0.09515745563119107,destabilizing
+NPM1,KCNB2,0.1256367230610996,destabilizing
+NPM1,ZNF521,0.09539232970722018,destabilizing
+NPM1,PLEKHA5,0.07282216912083808,destabilizing
+NPM1,NOVA1,0.10133936166222794,destabilizing
+NPM1,CCNY,0.10140092257754497,destabilizing
+NPM1,ARIH1,0.07855893919392691,destabilizing
+NPM1,EPB41L5,0.07402789129333277,destabilizing
+NPM1,GPR158,0.10985620366797935,destabilizing
+NPM1,NCOA2,0.0789225469426089,destabilizing
+NPM1,ALK,0.10844640155473693,destabilizing
+NPM1,IFT172,0.09407992510221112,destabilizing
+NPM1,DTWD2,0.14290606927885577,destabilizing
+NPM1,SIK3,0.08570433032835881,destabilizing
+NPM1,CPEB3,0.11516440665671474,destabilizing
+NPM1,XKR6,0.09902230745308858,destabilizing
+NPM1,TCF20,0.11849720933929508,destabilizing
+NPM1,CDKAL1,0.06724692239160715,destabilizing
+NPM1,DGKI,0.0796014112297712,destabilizing
+NPM1,EXOC6B,0.14655956697931413,destabilizing
+NPM1,MAGI3,0.10767373993105726,destabilizing
+NPM1,SBF2,0.06251580190719767,destabilizing
+NPM1,INPP4B,0.10086416398142574,destabilizing
+NPM1,ERC1,0.05642554723949178,destabilizing
+NPM1,PTPRS,0.12597551829716858,destabilizing
+NPM1,CBFA2T2,0.06590952713248922,destabilizing
+NPM1,SPDYE3,0.08246105909098501,destabilizing
+NPM1,DMD,0.13363962355749998,destabilizing
+NPM1,MCU,0.1107283945173135,destabilizing
+NPM1,SSH2,0.09568725809021587,destabilizing
+NPM1,DOCK3,0.12637858182257092,destabilizing
+NPM1,HS6ST3,0.11712945624208522,destabilizing
+NPM1,LPP,0.13820534733064704,destabilizing
+NPM1,STAG1,0.08192334011416254,destabilizing
+NPM1,CAPZA2,0.10529965739027931,destabilizing
+NPM1,GTF2IRD1,0.06977163568246394,destabilizing
+NPM1,CCBE1,0.051237964550155,destabilizing
+NPM1,TRIO,0.056167411971218946,destabilizing
+NPM1,BTBD9,0.10737786226915502,destabilizing
+NPM1,CNGB1,0.11735165525532658,destabilizing
+NPM1,FMN2,0.0691444546429003,destabilizing
+NPM1,ENSG00000228222,0.179684288876311,destabilizing
+NPM1,PRKN,0.14220536181211835,destabilizing
+NPM1,RASA2,0.11038976667839141,destabilizing
+NPM1,PPP1R12B,0.06813677541920404,destabilizing
+NPM1,WIPF2,0.10013942374921679,destabilizing
+NPM1,DLEU1,0.17610820507832436,destabilizing
+NPM1,KAZN,0.08692643198183359,destabilizing
+NPM1,FRMD5,0.09608121447507957,destabilizing
+NPM1,LINC00174,0.06194008764772754,destabilizing
+NPM1,PPM1E,0.07371463835094763,destabilizing
+NPM1,ARL3,0.0700802082344431,destabilizing
+NPM1,MBD5,0.07611505198986666,destabilizing
+NPM1,ELAVL3,0.08688571290825764,destabilizing
+NPM1,SLIT2,0.13164298005100386,destabilizing
+NPM1,UNC5C,0.10154774079845323,destabilizing
+NPM1,NEGR1,0.0869657447983242,destabilizing
+NPM1,ENOX1,0.13726533005434602,destabilizing
+NPM1,SCUBE1,0.0627165615677879,destabilizing
+NPM1,GPHN,0.1047893545419926,destabilizing
+NPM1,NAV3,0.09561307113041405,destabilizing
+NPM1,TOMM22,0.12691221296246813,destabilizing
+NPM1,AKAP6,0.09740645295251868,destabilizing
+NPM1,TMED2,0.07538224062118541,destabilizing
+NPM1,ZBTB20,0.07829770860625927,destabilizing
+NPM1,GRIK2,0.11975006477490832,destabilizing
+NPM1,SOX5,0.07468499449619069,destabilizing
+NPM1,LRRC37A3,0.1108627811086949,destabilizing
+NPM1,EYS,0.06530992419195618,destabilizing
+NPM1,MLLT3,0.14037889146460356,destabilizing
+NPM1,FMN1,0.06926550227441391,destabilizing
+NPM1,ADGRB3,0.07735416210729987,destabilizing
+NPM1,ROBO1,0.07739535689106691,destabilizing
+NPM1,PTPRD,0.06679036981421532,destabilizing
+NPM1,FAM155A,0.12382737575589126,destabilizing
+NPM1,LARP1B,0.10018276274403148,destabilizing
+YBX1,TRERF1,0.4429706355011732,destabilizing
+YBX1,SORCS1,0.3031170899856172,destabilizing
+YBX1,NCOA1,0.10722041378646789,destabilizing
+YBX1,COPA,0.20889777219090497,destabilizing
+YBX1,FCHSD2,0.20285088933597745,destabilizing
+YBX1,PDE3A,0.39892351414478616,destabilizing
+YBX1,UNC79,0.4468640780612493,destabilizing
+YBX1,DOC2B,0.34724721739843273,destabilizing
+YBX1,TMTC2,0.432240663810082,destabilizing
+YBX1,KALRN,0.2876320959757604,destabilizing
+YBX1,CHD1,0.22068689306210687,destabilizing
+YBX1,PAK3,0.12009348791367389,destabilizing
+YBX1,UBE2E2,0.1964799700160911,destabilizing
+YBX1,PPARD,0.2416893540662768,destabilizing
+YBX1,TOX,0.17701158669695058,destabilizing
+YBX1,BRAF,0.16923611311071265,destabilizing
+YBX1,RYR2,0.41894351179018596,destabilizing
+YBX1,ZNF609,0.09582562032814379,destabilizing
+YBX1,MTMR7,0.4697199809251823,destabilizing
+YBX1,EIF4E,0.42234793378195007,destabilizing
+YBX1,SOX11,0.14279560087602072,destabilizing
+YBX1,EPB41L4B,0.26325448573417903,destabilizing
+YBX1,CACNA1B,0.28291151938167475,destabilizing
+YBX1,TBC1D5,0.16126366306785403,destabilizing
+YBX1,WSB1,0.08260569029928964,destabilizing
+YBX1,LRRTM4,0.2962830048011456,destabilizing
+YBX1,SIRPA,0.3521721660271727,destabilizing
+YBX1,MAP4K3,0.0579721891390913,destabilizing
+YBX1,PTEN,0.2815846451085278,destabilizing
+YBX1,SPPL3,0.060475822527414305,destabilizing
+YBX1,FRY,0.48251746856508176,destabilizing
+YBX1,RUNX1T1,0.12750146137736104,destabilizing
+YBX1,MACROD2,0.3908676077503305,destabilizing
+YBX1,FOXN3,0.11102319340348646,destabilizing
+YBX1,SHANK2,0.44655063632728204,destabilizing
+YBX1,CDK12,0.5617810138289562,destabilizing
+YBX1,BMPR1B,0.06891668663190331,destabilizing
+YBX1,RFX7,0.436958047416639,destabilizing
+YBX1,UBR5,0.19859929196842974,destabilizing
+YBX1,JARID2,0.22669847837541238,destabilizing
+YBX1,MPHOSPH8,0.3606589550338517,destabilizing
+YBX1,RGS7,-0.07396699100766382,stabilizing
+YBX1,DIP2C,0.2824799962989856,destabilizing
+YBX1,ZNF423,0.15880633673529676,destabilizing
+YBX1,UBR3,0.2648786312554502,destabilizing
+YBX1,MGAT5,0.15176513703435848,destabilizing
+YBX1,DLG2,0.29341559427255753,destabilizing
+YBX1,CHST12,0.6053634026223167,destabilizing
+YBX1,EML5,0.47165881306583446,destabilizing
+YBX1,CENPP,0.5083447826431625,destabilizing
+YBX1,PSME4,0.36801808948108344,destabilizing
+YBX1,TMEM106B,0.41396844416216216,destabilizing
+YBX1,RABGAP1L,0.09940079520956686,destabilizing
+YBX1,EPHA5,0.33615413370067887,destabilizing
+YBX1,KCNB2,0.46679722476385405,destabilizing
+YBX1,ZNF83,0.2705233871824004,destabilizing
+YBX1,SOX6,0.29198019646010553,destabilizing
+YBX1,ZNF521,0.35293802652605755,destabilizing
+YBX1,PLEKHA5,0.24704308302744227,destabilizing
+YBX1,NOVA1,0.4810228256506923,destabilizing
+YBX1,CCNY,0.3787937139798254,destabilizing
+YBX1,ARIH1,0.3041948990909779,destabilizing
+YBX1,FAM171B,0.1283403733480262,destabilizing
+YBX1,EPB41L5,0.29964883714243,destabilizing
+YBX1,GPR158,0.39167952378958887,destabilizing
+YBX1,NCOA2,0.26491370272904224,destabilizing
+YBX1,PRKCB,0.062011520588138865,destabilizing
+YBX1,ALK,0.5089596293477326,destabilizing
+YBX1,ACACA,0.1594793249825426,destabilizing
+YBX1,ARHGAP26,0.13517814372079892,destabilizing
+YBX1,CTNND2,0.14077352823715653,destabilizing
+YBX1,IFT172,0.410846681380846,destabilizing
+YBX1,CCNT1,0.2800883035725918,destabilizing
+YBX1,ENAH,0.06689387084685891,destabilizing
+YBX1,DTWD2,0.5650015302443335,destabilizing
+YBX1,SIK3,0.32442124156751284,destabilizing
+YBX1,CPEB3,0.4288595965828285,destabilizing
+YBX1,CADM2,0.19932837234378617,destabilizing
+YBX1,KIF26B,0.0602158533351067,destabilizing
+YBX1,XKR6,0.4399879888187944,destabilizing
+YBX1,RMND5A,0.173177289779795,destabilizing
+YBX1,CADPS,0.22165001544207166,destabilizing
+YBX1,FGF13,0.1668328380601423,destabilizing
+YBX1,TCF20,0.43269572042349447,destabilizing
+YBX1,CDKAL1,0.23007269249924509,destabilizing
+YBX1,DGKI,0.3229662023199598,destabilizing
+YBX1,EXOC6B,0.47715156857220875,destabilizing
+YBX1,MAGI3,0.41139079821687596,destabilizing
+YBX1,SBF2,0.2097736394729808,destabilizing
+YBX1,INPP4B,0.34944423207845415,destabilizing
+YBX1,ERC1,0.17044155325175703,destabilizing
+YBX1,PTPRS,0.40564039855774714,destabilizing
+YBX1,CBFA2T2,0.21823549206646306,destabilizing
+YBX1,SPDYE3,0.2869001103850262,destabilizing
+YBX1,TMEM178B,0.18369648359729399,destabilizing
+YBX1,KMT2C,0.09582660268841654,destabilizing
+YBX1,CACNA2D1,0.12999649372686287,destabilizing
+YBX1,DMD,0.5806894186565913,destabilizing
+YBX1,EIF4G3,0.147996416842234,destabilizing
+YBX1,MCU,0.3881146414564626,destabilizing
+YBX1,SSH2,0.31076303436958297,destabilizing
+YBX1,TCF12,0.06016946565846027,destabilizing
+YBX1,DOCK3,0.4425452737712667,destabilizing
+YBX1,HS6ST3,0.3428561395139238,destabilizing
+YBX1,LPP,0.4149127571183795,destabilizing
+YBX1,STAG1,0.2646389359968578,destabilizing
+YBX1,CAPZA2,0.3749513073051356,destabilizing
+YBX1,ADGRL3,0.2259866275911756,destabilizing
+YBX1,PHACTR1,0.22547751925169188,destabilizing
+YBX1,UBE2R2,0.37349731578543605,destabilizing
+YBX1,GTF2IRD1,0.32120428890881214,destabilizing
+YBX1,CCBE1,0.18104097403485903,destabilizing
+YBX1,FTX,0.12691823563091054,destabilizing
+YBX1,VAPA,0.14430868530788177,destabilizing
+YBX1,JMJD1C,0.11443904839660486,destabilizing
+YBX1,TTC28,0.27274318623408345,destabilizing
+YBX1,SBNO1,0.23798035490190103,destabilizing
+YBX1,RIMS2,0.24424622831777626,destabilizing
+YBX1,IGF1R,0.16160535790153965,destabilizing
+YBX1,TRIO,0.13439305102805585,destabilizing
+YBX1,KCND2,0.12529981112693073,destabilizing
+YBX1,BTBD9,0.35456568989913656,destabilizing
+YBX1,CNGB1,0.47128558654120734,destabilizing
+YBX1,FMN2,0.33210134790716295,destabilizing
+YBX1,ENSG00000228222,0.574341449908456,destabilizing
+YBX1,ATXN1,0.1411056627066632,destabilizing
+YBX1,SYN3,0.13740927012657247,destabilizing
+YBX1,PRKN,0.457342390293766,destabilizing
+YBX1,RASA2,0.422753453322649,destabilizing
+YBX1,PPP1R12B,0.33911843071936315,destabilizing
+YBX1,FRMD4A,0.31493741508530565,destabilizing
+YBX1,CAMK1D,0.1493939879568913,destabilizing
+YBX1,PARD3,0.11702448483587202,destabilizing
+YBX1,SEMA6D,0.3735270999462794,destabilizing
+YBX1,WIPF2,0.41454153533650867,destabilizing
+YBX1,WWOX,0.06264659588558232,destabilizing
+YBX1,DLEU1,0.5182997982790133,destabilizing
+YBX1,TSHZ2,0.21542060693289394,destabilizing
+YBX1,MED13L,0.24610440825181634,destabilizing
+YBX1,AFF3,0.12016720671642786,destabilizing
+YBX1,KAZN,0.3286264924236311,destabilizing
+YBX1,KANSL1,0.26505847881405953,destabilizing
+YBX1,FRMD5,0.29720186521511593,destabilizing
+YBX1,LINC00174,0.376435795828166,destabilizing
+YBX1,PPM1E,0.28499447726511884,destabilizing
+YBX1,ARL3,0.27840629200806694,destabilizing
+YBX1,MBD5,0.3183354919497761,destabilizing
+YBX1,ELAVL3,0.354614652445774,destabilizing
+YBX1,SLIT2,0.4853016845352639,destabilizing
+YBX1,SLC8A1,0.15030217934116827,destabilizing
+YBX1,CLASP1,0.26486076643888,destabilizing
+YBX1,DOCK4,0.07295862340969984,destabilizing
+YBX1,UNC5C,0.3755201468729097,destabilizing
+YBX1,CACNA2D3,-0.15797079759910101,stabilizing
+YBX1,RC3H1,0.24541247716804607,destabilizing
+YBX1,NEGR1,0.3943826575142822,destabilizing
+YBX1,ENOX1,0.5178736455212859,destabilizing
+YBX1,SCUBE1,0.22316132599387922,destabilizing
+YBX1,GPHN,0.3007940890487196,destabilizing
+YBX1,NAV3,0.4249611074090873,destabilizing
+YBX1,EBF1,0.18755916612861084,destabilizing
+YBX1,TOMM22,0.4424492162211266,destabilizing
+YBX1,MBNL2,0.17479103027469503,destabilizing
+YBX1,ANKFN1,0.14193111825865135,destabilizing
+YBX1,MAGI2,0.20009382174583135,destabilizing
+YBX1,LSAMP,0.2583724074012091,destabilizing
+YBX1,AKAP6,0.39610101569415795,destabilizing
+YBX1,TMED2,0.28408152116596314,destabilizing
+YBX1,ZBTB20,0.36753114341597143,destabilizing
+YBX1,GRIK2,0.32233911099436713,destabilizing
+YBX1,MAML3,0.05171003563992947,destabilizing
+YBX1,SOX5,0.26917381694777154,destabilizing
+YBX1,LRRC37A3,0.49057638586838853,destabilizing
+YBX1,TMEM132C,0.12458423923476251,destabilizing
+YBX1,EYS,0.29397700269834626,destabilizing
+YBX1,ARID1B,0.25695170471658746,destabilizing
+YBX1,PRKCE,0.25489021241439785,destabilizing
+YBX1,RBFOX1,-0.15700527243325943,stabilizing
+YBX1,SDK1,0.1916835423761,destabilizing
+YBX1,NRG1,0.166177037938796,destabilizing
+YBX1,RORA,0.06370263990940372,destabilizing
+YBX1,MLLT3,0.5436783030099039,destabilizing
+YBX1,AUTS2,0.05940871522724359,destabilizing
+YBX1,FMN1,0.20489471953343227,destabilizing
+YBX1,ADGRB3,0.20532445312810813,destabilizing
+YBX1,ROBO1,0.31414899004249175,destabilizing
+YBX1,SYPL1,0.2407101470851787,destabilizing
+YBX1,PTPRD,0.3396302499613022,destabilizing
+YBX1,FAM155A,0.41124132919649814,destabilizing
+YBX1,LARP1B,0.40482904941765596,destabilizing
+CCAR2,UNC79,0.09674946476211432,destabilizing
+CCAR2,SHANK2,0.10821308837695442,destabilizing
+CCAR2,MPHOSPH8,0.07024654682597582,destabilizing
+CCAR2,KCNB2,0.08651747827067234,destabilizing
+CCAR2,SOX6,0.0619986936457862,destabilizing
+CCAR2,ZNF521,0.07219914495830056,destabilizing
+CCAR2,GPR158,0.07237744230155262,destabilizing
+CCAR2,ALK,0.10227118322785338,destabilizing
+CCAR2,XKR6,0.07791660027785634,destabilizing
+CCAR2,DGKI,0.07420012334405471,destabilizing
+CCAR2,MAGI3,0.0725787107107941,destabilizing
+CCAR2,DMD,0.08546841401294106,destabilizing
+CCAR2,DOCK3,0.08468825061991841,destabilizing
+CCAR2,ARL3,0.058419265244502264,destabilizing
+CCAR2,MBD5,0.065348776930466,destabilizing
+CCAR2,ELAVL3,0.07202521288002887,destabilizing
+CCAR2,CLASP1,0.08920853713173423,destabilizing
+CCAR2,ZBTB20,0.07759860959645316,destabilizing
+CCAR2,LRRC37A3,0.07506369946111245,destabilizing
+CCAR2,MLLT3,0.11546196108765294,destabilizing
+RC3H1,DMD,0.07951506747049308,destabilizing
+RC3H1,RC3H1,-0.32682500602392733,stabilizing
+RC3H1,NEGR1,0.07815257484670499,destabilizing
+RC3H2,MACROD2,0.0753571021816648,destabilizing
+RC3H2,NOVA1,0.09752047860100703,destabilizing
+RC3H2,MCU,0.0703606975144726,destabilizing
+RC3H2,GRIK2,0.05975284831162621,destabilizing
+RC3H2,MLLT3,0.0926944963188838,destabilizing
+ZC3H14,SORCS1,0.062468408844763595,destabilizing
+ZC3H14,MTMR7,0.09085532882253476,destabilizing
+ZC3H14,MACROD2,0.07036940408348105,destabilizing
+ZC3H14,CHST12,0.12703741464091658,destabilizing
+ZC3H14,CENPP,0.1167561327039653,destabilizing
+ZC3H14,ARIH1,0.06672268956759514,destabilizing
+ZC3H14,ALK,0.11871455313664732,destabilizing
+ZC3H14,XKR6,0.08906706048186112,destabilizing
+ZC3H14,TCF20,0.08992436574380913,destabilizing
+ZC3H14,EXOC6B,0.09375551360447461,destabilizing
+ZC3H14,DMD,0.08572902205879945,destabilizing
+ZC3H14,SSH2,0.08477938689772571,destabilizing
+ZC3H14,GTF2IRD1,0.059950383408239855,destabilizing
+ZC3H14,RASA2,0.06705422871558665,destabilizing
+ZC3H14,WIPF2,0.07204819175231861,destabilizing
+ZC3H14,SOX5,0.07141728599262201,destabilizing
+ZC3H14,LRRC37A3,0.09179153794229465,destabilizing
+ZC3H14,MLLT3,0.08759109579664744,destabilizing
+ZC3H14,PTPRD,0.07124232441863297,destabilizing
+CNBP,TRERF1,0.2330695709332459,destabilizing
+CNBP,SORCS1,0.13489062579545238,destabilizing
+CNBP,NCOA1,0.08187448315913956,destabilizing
+CNBP,COPA,0.08362617050435153,destabilizing
+CNBP,FCHSD2,0.0931245363971432,destabilizing
+CNBP,PDE3A,0.24038553446076105,destabilizing
+CNBP,UNC79,0.21302325445463138,destabilizing
+CNBP,DOC2B,0.15512520209807001,destabilizing
+CNBP,TMTC2,0.2007284252261391,destabilizing
+CNBP,KALRN,0.14551416925731273,destabilizing
+CNBP,CHD1,0.10630509961763976,destabilizing
+CNBP,PAK3,0.05700001653649185,destabilizing
+CNBP,UBE2E2,0.09904629073489721,destabilizing
+CNBP,PPARD,0.1210797421399581,destabilizing
+CNBP,TOX,0.10979570840219727,destabilizing
+CNBP,BRAF,0.08130002652033318,destabilizing
+CNBP,RYR2,0.23388049247651566,destabilizing
+CNBP,MTMR7,0.23344816534957372,destabilizing
+CNBP,EIF4E,0.1917712828920973,destabilizing
+CNBP,SOX11,0.05511268060442208,destabilizing
+CNBP,EPB41L4B,0.10657172854690049,destabilizing
+CNBP,CACNA1B,0.136209531778789,destabilizing
+CNBP,LRRTM4,0.1286135456440787,destabilizing
+CNBP,SIRPA,0.16356353838670248,destabilizing
+CNBP,PTEN,0.13016337361851663,destabilizing
+CNBP,FRY,0.2494256837735427,destabilizing
+CNBP,MACROD2,0.19820254907341786,destabilizing
+CNBP,FOXN3,0.07704745189531649,destabilizing
+CNBP,SHANK2,0.2694818014910361,destabilizing
+CNBP,CDK12,0.26385969024344763,destabilizing
+CNBP,RFX7,0.21684158243418933,destabilizing
+CNBP,UBR5,0.11142976267476404,destabilizing
+CNBP,JARID2,0.11650699959868227,destabilizing
+CNBP,MPHOSPH8,0.17011044381512805,destabilizing
+CNBP,DIP2C,0.121728196708477,destabilizing
+CNBP,ZNF423,0.07849605235308067,destabilizing
+CNBP,UBR3,0.1475203210214788,destabilizing
+CNBP,MGAT5,0.08214633926892045,destabilizing
+CNBP,DLG2,0.12598705878656222,destabilizing
+CNBP,CHST12,0.28176835217262675,destabilizing
+CNBP,EML5,0.21613028552926564,destabilizing
+CNBP,CENPP,0.24319043191481501,destabilizing
+CNBP,PSME4,0.19677045843288438,destabilizing
+CNBP,TMEM106B,0.18844371150711484,destabilizing
+CNBP,RABGAP1L,0.06030274695056791,destabilizing
+CNBP,EPHA5,0.18025506644186506,destabilizing
+CNBP,KCNB2,0.2099592610017303,destabilizing
+CNBP,ZNF83,0.151493277329472,destabilizing
+CNBP,SOX6,0.13447198339195043,destabilizing
+CNBP,ZNF521,0.16704025419563664,destabilizing
+CNBP,PLEKHA5,0.12717987943459483,destabilizing
+CNBP,NOVA1,0.22294628532669494,destabilizing
+CNBP,CCNY,0.18734901817828728,destabilizing
+CNBP,ARIH1,0.16960102469696783,destabilizing
+CNBP,EPB41L5,0.13499292566543147,destabilizing
+CNBP,GPR158,0.21513619785867286,destabilizing
+CNBP,NCOA2,0.14514909897074163,destabilizing
+CNBP,ALK,0.2228112232910113,destabilizing
+CNBP,ACACA,0.08003405177398412,destabilizing
+CNBP,ARHGAP26,0.08233633083475521,destabilizing
+CNBP,CTNND2,0.0962960213595854,destabilizing
+CNBP,IFT172,0.17331259176911212,destabilizing
+CNBP,CCNT1,0.12681770422137364,destabilizing
+CNBP,DTWD2,0.2631442931757738,destabilizing
+CNBP,SIK3,0.1557158362286727,destabilizing
+CNBP,CPEB3,0.20436899081455345,destabilizing
+CNBP,CADM2,0.09388155034248341,destabilizing
+CNBP,XKR6,0.21446305728894058,destabilizing
+CNBP,CADPS,0.09997184589612852,destabilizing
+CNBP,FGF13,0.0897579777600576,destabilizing
+CNBP,TCF20,0.19949562620773204,destabilizing
+CNBP,CDKAL1,0.08866561978806892,destabilizing
+CNBP,DGKI,0.17110251388610132,destabilizing
+CNBP,EXOC6B,0.22332457041016307,destabilizing
+CNBP,MAGI3,0.18860323554990915,destabilizing
+CNBP,SBF2,0.11236101099845117,destabilizing
+CNBP,INPP4B,0.16056118782270298,destabilizing
+CNBP,ERC1,0.07608005388936538,destabilizing
+CNBP,PTPRS,0.23581652729243918,destabilizing
+CNBP,CBFA2T2,0.1020306603555768,destabilizing
+CNBP,SPDYE3,0.17535926184401904,destabilizing
+CNBP,TMEM178B,0.10792552977107668,destabilizing
+CNBP,KMT2C,0.054100902704718054,destabilizing
+CNBP,DMD,0.2724850532379816,destabilizing
+CNBP,EIF4G3,0.08761291956394476,destabilizing
+CNBP,MCU,0.186165660849652,destabilizing
+CNBP,SSH2,0.16515999994030878,destabilizing
+CNBP,DOCK3,0.2392503795891179,destabilizing
+CNBP,HS6ST3,0.16146960004701771,destabilizing
+CNBP,LPP,0.22682345713922136,destabilizing
+CNBP,STAG1,0.1391813910882292,destabilizing
+CNBP,CAPZA2,0.17374031684044763,destabilizing
+CNBP,ADGRL3,0.06686175348930243,destabilizing
+CNBP,PHACTR1,0.09968180427985858,destabilizing
+CNBP,UBE2R2,0.18742552599439014,destabilizing
+CNBP,GTF2IRD1,0.15167140472842922,destabilizing
+CNBP,CCBE1,0.09029745076376428,destabilizing
+CNBP,FTX,0.061022036965520214,destabilizing
+CNBP,JMJD1C,0.05383515899122704,destabilizing
+CNBP,TTC28,0.14569459019935785,destabilizing
+CNBP,SBNO1,0.08151752054759459,destabilizing
+CNBP,RIMS2,0.10839173596241118,destabilizing
+CNBP,IGF1R,0.0637394180897369,destabilizing
+CNBP,TRIO,0.09562820572203952,destabilizing
+CNBP,KCND2,0.06512228752084631,destabilizing
+CNBP,BTBD9,0.16203947016212542,destabilizing
+CNBP,CNGB1,0.21121497750204574,destabilizing
+CNBP,FMN2,0.146536947344135,destabilizing
+CNBP,ENSG00000228222,0.31093020079477757,destabilizing
+CNBP,ATXN1,0.07580125461296845,destabilizing
+CNBP,SYN3,0.05764701113682366,destabilizing
+CNBP,PRKN,0.18839394390618455,destabilizing
+CNBP,RASA2,0.19631459623769404,destabilizing
+CNBP,PPP1R12B,0.1341068097023488,destabilizing
+CNBP,FRMD4A,0.12141586826229643,destabilizing
+CNBP,CAMK1D,0.08866501020381437,destabilizing
+CNBP,PARD3,0.05554675484338179,destabilizing
+CNBP,SEMA6D,0.178547915108923,destabilizing
+CNBP,WIPF2,0.18631952718537045,destabilizing
+CNBP,DLEU1,0.25669326442476265,destabilizing
+CNBP,TSHZ2,0.10166079309505478,destabilizing
+CNBP,MED13L,0.13479192434973306,destabilizing
+CNBP,KAZN,0.16911191704223538,destabilizing
+CNBP,KANSL1,0.1161983234883238,destabilizing
+CNBP,FRMD5,0.15832578715064866,destabilizing
+CNBP,LINC00174,0.15055036146039258,destabilizing
+CNBP,PPM1E,0.1606085272379591,destabilizing
+CNBP,ARL3,0.12286511801157429,destabilizing
+CNBP,MBD5,0.15859526234962473,destabilizing
+CNBP,ELAVL3,0.1767601757672355,destabilizing
+CNBP,SLIT2,0.23065362831013692,destabilizing
+CNBP,SLC8A1,0.057240091838459364,destabilizing
+CNBP,CLASP1,0.14714144701611948,destabilizing
+CNBP,DOCK4,0.06101521592278068,destabilizing
+CNBP,UNC5C,0.16834372022942357,destabilizing
+CNBP,CACNA2D3,-0.051640891490709176,stabilizing
+CNBP,RC3H1,0.11987174174099177,destabilizing
+CNBP,NEGR1,0.18803939014736315,destabilizing
+CNBP,ENOX1,0.24605253564466179,destabilizing
+CNBP,SCUBE1,0.09510947061727568,destabilizing
+CNBP,GPHN,0.10431442074131418,destabilizing
+CNBP,NAV3,0.20128296606794407,destabilizing
+CNBP,EBF1,0.08565827899879029,destabilizing
+CNBP,TOMM22,0.20404453019455662,destabilizing
+CNBP,MBNL2,0.11143843926572711,destabilizing
+CNBP,ANKFN1,0.07270145400373794,destabilizing
+CNBP,MAGI2,0.07234440262540891,destabilizing
+CNBP,LSAMP,0.11539294668222246,destabilizing
+CNBP,AKAP6,0.18266864524912044,destabilizing
+CNBP,TMED2,0.10165492604454397,destabilizing
+CNBP,ZBTB20,0.1600804343874328,destabilizing
+CNBP,GRIK2,0.1612773717434394,destabilizing
+CNBP,SOX5,0.1226310526990406,destabilizing
+CNBP,LRRC37A3,0.23628428536201104,destabilizing
+CNBP,TMEM132C,0.05752240286544856,destabilizing
+CNBP,EYS,0.1418868693778564,destabilizing
+CNBP,ARID1B,0.1222266256864159,destabilizing
+CNBP,PRKCE,0.12980480849329146,destabilizing
+CNBP,RBFOX1,-0.07676030221300414,stabilizing
+CNBP,SDK1,0.10032667763914768,destabilizing
+CNBP,NRG1,0.08976734957807628,destabilizing
+CNBP,MLLT3,0.2307534636418956,destabilizing
+CNBP,FMN1,0.11689179087780763,destabilizing
+CNBP,ADGRB3,0.120192701007024,destabilizing
+CNBP,ROBO1,0.13923707911210317,destabilizing
+CNBP,SYPL1,0.11117038781720473,destabilizing
+CNBP,PTPRD,0.1415339956673915,destabilizing
+CNBP,FAM155A,0.2071089103640166,destabilizing
+CNBP,LARP1B,0.174894806881681,destabilizing
+PPIG,TRERF1,0.23421325393618553,destabilizing
+PPIG,SORCS1,0.1557291594392897,destabilizing
+PPIG,NCOA1,0.07924863522946156,destabilizing
+PPIG,COPA,0.07112637170992268,destabilizing
+PPIG,FCHSD2,0.11604015364762017,destabilizing
+PPIG,PDE3A,0.21741761410729524,destabilizing
+PPIG,UNC79,0.2506126291264538,destabilizing
+PPIG,DOC2B,0.15731830291154575,destabilizing
+PPIG,TMTC2,0.2289637074717752,destabilizing
+PPIG,KALRN,0.167799078121521,destabilizing
+PPIG,CHD1,0.1313439236999688,destabilizing
+PPIG,PAK3,0.05332328063723589,destabilizing
+PPIG,UBE2E2,0.1033353777683222,destabilizing
+PPIG,PPARD,0.12416032463152152,destabilizing
+PPIG,BRAF,0.06933254468998702,destabilizing
+PPIG,RYR2,0.17030048085207553,destabilizing
+PPIG,MTMR7,0.23889798477100196,destabilizing
+PPIG,EIF4E,0.23584929376914543,destabilizing
+PPIG,SOX11,0.07704641814119338,destabilizing
+PPIG,EPB41L4B,0.14093997313521045,destabilizing
+PPIG,CACNA1B,0.15374776772438128,destabilizing
+PPIG,TBC1D5,0.0561733448342639,destabilizing
+PPIG,LRRTM4,0.15592574904590603,destabilizing
+PPIG,SIRPA,0.22751991455742723,destabilizing
+PPIG,PTEN,0.16230049592006315,destabilizing
+PPIG,FRY,0.2392784668815835,destabilizing
+PPIG,MACROD2,0.21556727311625407,destabilizing
+PPIG,FOXN3,0.059711634731595624,destabilizing
+PPIG,SHANK2,0.31034505322871486,destabilizing
+PPIG,CDK12,0.29576525794796754,destabilizing
+PPIG,RFX7,0.24888100050965786,destabilizing
+PPIG,UBR5,0.10848065391347508,destabilizing
+PPIG,JARID2,0.12361842247021526,destabilizing
+PPIG,MPHOSPH8,0.18099452602148877,destabilizing
+PPIG,DIP2C,0.13878060741857776,destabilizing
+PPIG,ZNF423,0.08305085352491276,destabilizing
+PPIG,UBR3,0.1328362802333177,destabilizing
+PPIG,MGAT5,0.1009107893636596,destabilizing
+PPIG,DLG2,0.13581049355160682,destabilizing
+PPIG,CHST12,0.33409092502630694,destabilizing
+PPIG,EML5,0.24164227598019344,destabilizing
+PPIG,CENPP,0.2496737498558102,destabilizing
+PPIG,PSME4,0.222702234348556,destabilizing
+PPIG,TMEM106B,0.23374168933882747,destabilizing
+PPIG,EPHA5,0.1795695339449547,destabilizing
+PPIG,KCNB2,0.2176851523873518,destabilizing
+PPIG,ZNF83,0.16985442399767545,destabilizing
+PPIG,SOX6,0.12937541415778805,destabilizing
+PPIG,ZNF521,0.19064210024142247,destabilizing
+PPIG,PLEKHA5,0.11901759417553329,destabilizing
+PPIG,NOVA1,0.2106860780935468,destabilizing
+PPIG,CCNY,0.23725032677234595,destabilizing
+PPIG,ARIH1,0.15469991684090956,destabilizing
+PPIG,EPB41L5,0.16386947101576227,destabilizing
+PPIG,GPR158,0.2025314833061863,destabilizing
+PPIG,NCOA2,0.16954888355665618,destabilizing
+PPIG,ALK,0.24205544897596734,destabilizing
+PPIG,ACACA,0.09409172557547871,destabilizing
+PPIG,ARHGAP26,0.05520876418115928,destabilizing
+PPIG,CTNND2,0.08207501757149559,destabilizing
+PPIG,IFT172,0.20839946664228895,destabilizing
+PPIG,CCNT1,0.13031028194027772,destabilizing
+PPIG,DTWD2,0.2996184791447315,destabilizing
+PPIG,SIK3,0.19254945061624698,destabilizing
+PPIG,CPEB3,0.2094511527988063,destabilizing
+PPIG,CADM2,0.09692494121819199,destabilizing
+PPIG,XKR6,0.23616271492301671,destabilizing
+PPIG,RMND5A,0.08428819332337022,destabilizing
+PPIG,CADPS,0.12145777561683496,destabilizing
+PPIG,FGF13,0.07126495818559693,destabilizing
+PPIG,TCF20,0.2216911600341142,destabilizing
+PPIG,CDKAL1,0.1273841084166674,destabilizing
+PPIG,DGKI,0.16538162033195752,destabilizing
+PPIG,EXOC6B,0.2783644678532663,destabilizing
+PPIG,MAGI3,0.21643013602964004,destabilizing
+PPIG,SBF2,0.111859845756935,destabilizing
+PPIG,INPP4B,0.17656572734672968,destabilizing
+PPIG,ERC1,0.07402871266727888,destabilizing
+PPIG,PTPRS,0.2210361202645304,destabilizing
+PPIG,CBFA2T2,0.09719391336358782,destabilizing
+PPIG,SPDYE3,0.1880540466084861,destabilizing
+PPIG,TMEM178B,0.10224658025079417,destabilizing
+PPIG,KMT2C,0.0546993981199207,destabilizing
+PPIG,DMD,0.30722607019922893,destabilizing
+PPIG,EIF4G3,0.06279069889728765,destabilizing
+PPIG,MCU,0.19379866827982678,destabilizing
+PPIG,SSH2,0.18060100656288508,destabilizing
+PPIG,DOCK3,0.2527332693359536,destabilizing
+PPIG,HS6ST3,0.21051383995185297,destabilizing
+PPIG,LPP,0.24731844977178502,destabilizing
+PPIG,STAG1,0.16710004375831455,destabilizing
+PPIG,CAPZA2,0.19412996326170787,destabilizing
+PPIG,ADGRL3,0.08537483649027325,destabilizing
+PPIG,PHACTR1,0.0849163548660841,destabilizing
+PPIG,UBE2R2,0.21354600387116823,destabilizing
+PPIG,GTF2IRD1,0.16971599960879524,destabilizing
+PPIG,CCBE1,0.10411082726736734,destabilizing
+PPIG,FTX,0.0547710873754395,destabilizing
+PPIG,TTC28,0.14825990521499927,destabilizing
+PPIG,SBNO1,0.12186382897960386,destabilizing
+PPIG,RIMS2,0.127818637522835,destabilizing
+PPIG,IGF1R,0.08563395202956459,destabilizing
+PPIG,TRIO,0.10882191530053939,destabilizing
+PPIG,KCND2,0.0624398883020082,destabilizing
+PPIG,BTBD9,0.20278333654844252,destabilizing
+PPIG,CNGB1,0.2301595205436642,destabilizing
+PPIG,FMN2,0.17534837341105125,destabilizing
+PPIG,ENSG00000228222,0.34708148288210044,destabilizing
+PPIG,ATXN1,0.06788192715999013,destabilizing
+PPIG,SYN3,0.05470700757041222,destabilizing
+PPIG,PRKN,0.2652453897933961,destabilizing
+PPIG,RASA2,0.21115458698577044,destabilizing
+PPIG,PPP1R12B,0.14606148779753467,destabilizing
+PPIG,FRMD4A,0.15655785332697805,destabilizing
+PPIG,CAMK1D,0.09061479361956856,destabilizing
+PPIG,PARD3,0.06843814224561975,destabilizing
+PPIG,SEMA6D,0.18008073309965403,destabilizing
+PPIG,WIPF2,0.21233228159780682,destabilizing
+PPIG,DLEU1,0.25877146948897795,destabilizing
+PPIG,TSHZ2,0.12904520998922397,destabilizing
+PPIG,MED13L,0.12214039951966957,destabilizing
+PPIG,AFF3,0.06515585001750031,destabilizing
+PPIG,KAZN,0.176243609196917,destabilizing
+PPIG,KANSL1,0.12228916066301108,destabilizing
+PPIG,FRMD5,0.17383531655636106,destabilizing
+PPIG,LINC00174,0.19551342498800545,destabilizing
+PPIG,PPM1E,0.16551889226478889,destabilizing
+PPIG,ARL3,0.1320266186267437,destabilizing
+PPIG,MBD5,0.15316883073068027,destabilizing
+PPIG,ELAVL3,0.1883830838146014,destabilizing
+PPIG,SLIT2,0.26060087533993775,destabilizing
+PPIG,CLASP1,0.15351589619594605,destabilizing
+PPIG,DOCK4,0.060883646773088766,destabilizing
+PPIG,UNC5C,0.19969096632541192,destabilizing
+PPIG,CACNA2D3,-0.08307923432683706,stabilizing
+PPIG,RC3H1,0.1433466225265522,destabilizing
+PPIG,NEGR1,0.1985680350927041,destabilizing
+PPIG,ENOX1,0.3001031687276077,destabilizing
+PPIG,SCUBE1,0.132490970244361,destabilizing
+PPIG,GPHN,0.1595701474414279,destabilizing
+PPIG,NAV3,0.22579337861736465,destabilizing
+PPIG,EBF1,0.09162553128807703,destabilizing
+PPIG,TOMM22,0.24535750108065085,destabilizing
+PPIG,MBNL2,0.0871276983240801,destabilizing
+PPIG,ANKFN1,0.06702375393877204,destabilizing
+PPIG,MAGI2,0.0934117020205039,destabilizing
+PPIG,LSAMP,0.12478996640065956,destabilizing
+PPIG,AKAP6,0.1977867351081244,destabilizing
+PPIG,TMED2,0.14627576716016513,destabilizing
+PPIG,ZBTB20,0.203461388728156,destabilizing
+PPIG,GRIK2,0.18509606967154027,destabilizing
+PPIG,SOX5,0.1261649239154738,destabilizing
+PPIG,LRRC37A3,0.25650868629078,destabilizing
+PPIG,TMEM132C,0.05592092776582147,destabilizing
+PPIG,EYS,0.15210789902771923,destabilizing
+PPIG,ARID1B,0.12484534719928309,destabilizing
+PPIG,PRKCE,0.130284656107738,destabilizing
+PPIG,RBFOX1,-0.10513757676803191,stabilizing
+PPIG,SDK1,0.1109440604945253,destabilizing
+PPIG,NRG1,0.07122836543243567,destabilizing
+PPIG,MLLT3,0.28273203949078474,destabilizing
+PPIG,FMN1,0.11355580928948061,destabilizing
+PPIG,ADGRB3,0.0838537944605083,destabilizing
+PPIG,ROBO1,0.1881714871262203,destabilizing
+PPIG,SYPL1,0.09199217942916772,destabilizing
+PPIG,PTPRD,0.1727464470132989,destabilizing
+PPIG,FAM155A,0.235029083029089,destabilizing
+PPIG,LARP1B,0.21786504495926917,destabilizing
+AUH,TRERF1,0.11381376597546872,destabilizing
+AUH,SORCS1,0.07207290182059317,destabilizing
+AUH,PDE3A,0.11980080862892836,destabilizing
+AUH,UNC79,0.12246101045386529,destabilizing
+AUH,DOC2B,0.1052072399387271,destabilizing
+AUH,TMTC2,0.09523057560922767,destabilizing
+AUH,KALRN,0.08865092435204347,destabilizing
+AUH,CHD1,0.06155488601042816,destabilizing
+AUH,MTMR7,0.08959125130755467,destabilizing
+AUH,EPB41L4B,0.06933781781941652,destabilizing
+AUH,CACNA1B,0.08138015661169293,destabilizing
+AUH,LRRTM4,0.07956113885276583,destabilizing
+AUH,FRY,0.1008654333134459,destabilizing
+AUH,MACROD2,0.09755794174850747,destabilizing
+AUH,SHANK2,0.13757217915753062,destabilizing
+AUH,CDK12,0.13255394107103974,destabilizing
+AUH,RFX7,0.10624064829494005,destabilizing
+AUH,UBR5,0.07122073805685633,destabilizing
+AUH,MPHOSPH8,0.08346778893726937,destabilizing
+AUH,DIP2C,0.07545032752047685,destabilizing
+AUH,DLG2,0.07956835762313794,destabilizing
+AUH,CHST12,0.17601896062300038,destabilizing
+AUH,EML5,0.147766516784252,destabilizing
+AUH,PSME4,0.08645184936320038,destabilizing
+AUH,TMEM106B,0.0927968350514068,destabilizing
+AUH,EPHA5,0.08709361164514884,destabilizing
+AUH,KCNB2,0.10281389180273194,destabilizing
+AUH,ZNF83,0.1023779682793225,destabilizing
+AUH,ZNF521,0.10026312456458197,destabilizing
+AUH,PLEKHA5,0.06020114086721197,destabilizing
+AUH,NOVA1,0.1313777529900852,destabilizing
+AUH,CCNY,0.10931778133295621,destabilizing
+AUH,ARIH1,0.06973760856163404,destabilizing
+AUH,EPB41L5,0.07641277628427695,destabilizing
+AUH,GPR158,0.10467185126013744,destabilizing
+AUH,NCOA2,0.07819001460182137,destabilizing
+AUH,IFT172,0.0957652904202009,destabilizing
+AUH,SIK3,0.08291704344366466,destabilizing
+AUH,CPEB3,0.09797692629177576,destabilizing
+AUH,XKR6,0.08920649893435954,destabilizing
+AUH,CADPS,0.06841913034823126,destabilizing
+AUH,TCF20,0.11157768927119108,destabilizing
+AUH,EXOC6B,0.12673676431401665,destabilizing
+AUH,MAGI3,0.10526733892028754,destabilizing
+AUH,INPP4B,0.10342441748330906,destabilizing
+AUH,SPDYE3,0.07132079574158692,destabilizing
+AUH,DMD,0.1408998117976255,destabilizing
+AUH,MCU,0.0622823307620299,destabilizing
+AUH,SSH2,0.09008643903732827,destabilizing
+AUH,DOCK3,0.1212872186833663,destabilizing
+AUH,HS6ST3,0.12572743278476414,destabilizing
+AUH,LPP,0.14455568237614558,destabilizing
+AUH,STAG1,0.07133766040696307,destabilizing
+AUH,CAPZA2,0.10741004850515835,destabilizing
+AUH,ADGRL3,0.06385772080456359,destabilizing
+AUH,UBE2R2,0.10412379977120731,destabilizing
+AUH,GTF2IRD1,0.07871998843587737,destabilizing
+AUH,CCBE1,0.05860473088719843,destabilizing
+AUH,TTC28,0.08237752742940542,destabilizing
+AUH,TRIO,0.06217988373794676,destabilizing
+AUH,BTBD9,0.11153723360547463,destabilizing
+AUH,CNGB1,0.11692465641365536,destabilizing
+AUH,FMN2,0.07039502682635741,destabilizing
+AUH,ENSG00000228222,0.12313706643296482,destabilizing
+AUH,PRKN,0.13377733993614427,destabilizing
+AUH,RASA2,0.09379975374338649,destabilizing
+AUH,PPP1R12B,0.06821809158933229,destabilizing
+AUH,FRMD4A,0.07950560875565349,destabilizing
+AUH,SEMA6D,0.06743653617982538,destabilizing
+AUH,WIPF2,0.10264815026854529,destabilizing
+AUH,DLEU1,0.15053264850272727,destabilizing
+AUH,MED13L,0.07547120784526071,destabilizing
+AUH,KAZN,0.08341913590431291,destabilizing
+AUH,FRMD5,0.10174234119602328,destabilizing
+AUH,LINC00174,0.1020050357799726,destabilizing
+AUH,PPM1E,0.08607968028878107,destabilizing
+AUH,MBD5,0.07556063650947617,destabilizing
+AUH,ELAVL3,0.08567304954360801,destabilizing
+AUH,SLIT2,0.15535362618873577,destabilizing
+AUH,UNC5C,0.06751238068097463,destabilizing
+AUH,NEGR1,0.0832153419431811,destabilizing
+AUH,ENOX1,0.11330066576686532,destabilizing
+AUH,NAV3,0.11582213413505249,destabilizing
+AUH,TOMM22,0.1301811593924565,destabilizing
+AUH,LSAMP,0.05531631449382073,destabilizing
+AUH,AKAP6,0.08247582379277249,destabilizing
+AUH,TMED2,0.06486272438295305,destabilizing
+AUH,ZBTB20,0.09003905220325673,destabilizing
+AUH,GRIK2,0.10085709070543444,destabilizing
+AUH,SOX5,0.07480062573156927,destabilizing
+AUH,LRRC37A3,0.11597823098280143,destabilizing
+AUH,EYS,0.07517720045781708,destabilizing
+AUH,PRKCE,0.07988381489636617,destabilizing
+AUH,RBFOX1,-0.06857037840478526,stabilizing
+AUH,MLLT3,0.12127615287655916,destabilizing
+AUH,ADGRB3,0.06679625999865621,destabilizing
+AUH,ROBO1,0.10304528763653986,destabilizing
+AUH,PTPRD,0.07253812752587618,destabilizing
+AUH,FAM155A,0.11026517466464393,destabilizing
+AUH,LARP1B,0.10403416536076246,destabilizing
+SYNCRIP,EIF4E,0.1033754224240055,destabilizing
+SYNCRIP,CDK12,0.10032831107929172,destabilizing
+SYNCRIP,RFX7,0.09721085249361593,destabilizing
+SYNCRIP,MPHOSPH8,0.08646519699090287,destabilizing
+SYNCRIP,KCNB2,0.09267174582476594,destabilizing
+SYNCRIP,CCNT1,0.05412580620211254,destabilizing
+SYNCRIP,XKR6,0.07688385424325468,destabilizing
+SYNCRIP,DMD,0.08534311499001174,destabilizing
+SYNCRIP,MCU,0.07133768765461183,destabilizing
+SYNCRIP,DOCK3,0.0744569567844499,destabilizing
+SYNCRIP,FRMD5,0.0694179915397288,destabilizing
+SYNCRIP,LINC00174,0.06170871235137538,destabilizing
+SYNCRIP,ELAVL3,0.06463101101063014,destabilizing
+SYNCRIP,ENOX1,0.12630508329232445,destabilizing
+SYNCRIP,ZBTB20,0.08679639701464294,destabilizing
+SYNCRIP,MLLT3,0.1018704056611303,destabilizing
+TRNAU1AP,TRERF1,0.17747469576298505,destabilizing
+TRNAU1AP,SORCS1,0.09006817594238828,destabilizing
+TRNAU1AP,FCHSD2,0.06663917025416437,destabilizing
+TRNAU1AP,PDE3A,0.14450432239764985,destabilizing
+TRNAU1AP,UNC79,0.14294533053614183,destabilizing
+TRNAU1AP,DOC2B,0.09405192626603642,destabilizing
+TRNAU1AP,TMTC2,0.12206133217211733,destabilizing
+TRNAU1AP,KALRN,0.11979826879016,destabilizing
+TRNAU1AP,CHD1,0.07903399028105561,destabilizing
+TRNAU1AP,PPARD,0.06745648426953996,destabilizing
+TRNAU1AP,RYR2,0.12987845224505096,destabilizing
+TRNAU1AP,MTMR7,0.1356395545086321,destabilizing
+TRNAU1AP,EIF4E,0.10546567873102584,destabilizing
+TRNAU1AP,SOX11,0.05854419519869482,destabilizing
+TRNAU1AP,EPB41L4B,0.0978233583022297,destabilizing
+TRNAU1AP,CACNA1B,0.0800326939960666,destabilizing
+TRNAU1AP,LRRTM4,0.09852558946471247,destabilizing
+TRNAU1AP,SIRPA,0.10464129773599107,destabilizing
+TRNAU1AP,PTEN,0.09272351633990643,destabilizing
+TRNAU1AP,FRY,0.14498552530058423,destabilizing
+TRNAU1AP,MACROD2,0.12810351361760638,destabilizing
+TRNAU1AP,SHANK2,0.15405150095463294,destabilizing
+TRNAU1AP,CDK12,0.17678720341126697,destabilizing
+TRNAU1AP,RFX7,0.1135027102589059,destabilizing
+TRNAU1AP,UBR5,0.07914482720592837,destabilizing
+TRNAU1AP,JARID2,0.07440654552996119,destabilizing
+TRNAU1AP,MPHOSPH8,0.10629186987272288,destabilizing
+TRNAU1AP,DIP2C,0.10752307517778316,destabilizing
+TRNAU1AP,UBR3,0.09640428177337743,destabilizing
+TRNAU1AP,DLG2,0.0924031460616727,destabilizing
+TRNAU1AP,CHST12,0.1803449926889445,destabilizing
+TRNAU1AP,EML5,0.14496716000199777,destabilizing
+TRNAU1AP,CENPP,0.16886108142094838,destabilizing
+TRNAU1AP,PSME4,0.10039594592689197,destabilizing
+TRNAU1AP,TMEM106B,0.11077471921359633,destabilizing
+TRNAU1AP,EPHA5,0.07233386337264194,destabilizing
+TRNAU1AP,KCNB2,0.13057089308986738,destabilizing
+TRNAU1AP,ZNF83,0.10753670171819601,destabilizing
+TRNAU1AP,SOX6,0.09885759266337428,destabilizing
+TRNAU1AP,ZNF521,0.11272705842429667,destabilizing
+TRNAU1AP,PLEKHA5,0.07850243628333613,destabilizing
+TRNAU1AP,NOVA1,0.1568753828587085,destabilizing
+TRNAU1AP,CCNY,0.11150670311214066,destabilizing
+TRNAU1AP,ARIH1,0.09885985150324082,destabilizing
+TRNAU1AP,FAM171B,0.051339603269793456,destabilizing
+TRNAU1AP,EPB41L5,0.1040816934770572,destabilizing
+TRNAU1AP,GPR158,0.1056126644447438,destabilizing
+TRNAU1AP,NCOA2,0.09329273186169709,destabilizing
+TRNAU1AP,ALK,0.12946691505309552,destabilizing
+TRNAU1AP,ACACA,0.056759707822584576,destabilizing
+TRNAU1AP,CTNND2,0.06696124199169545,destabilizing
+TRNAU1AP,IFT172,0.124125090106572,destabilizing
+TRNAU1AP,CCNT1,0.06212278330352711,destabilizing
+TRNAU1AP,SIK3,0.11682830630093684,destabilizing
+TRNAU1AP,CPEB3,0.12640140413504017,destabilizing
+TRNAU1AP,CADM2,0.061591505209928,destabilizing
+TRNAU1AP,XKR6,0.15384115652274447,destabilizing
+TRNAU1AP,CADPS,0.07408659031403346,destabilizing
+TRNAU1AP,FGF13,0.0689925047187346,destabilizing
+TRNAU1AP,TCF20,0.12024731231840828,destabilizing
+TRNAU1AP,CDKAL1,0.07292684001624254,destabilizing
+TRNAU1AP,DGKI,0.09674846818603439,destabilizing
+TRNAU1AP,EXOC6B,0.144285565328374,destabilizing
+TRNAU1AP,MAGI3,0.12692127657946553,destabilizing
+TRNAU1AP,SBF2,0.08113121899387347,destabilizing
+TRNAU1AP,INPP4B,0.12314757084818988,destabilizing
+TRNAU1AP,PTPRS,0.128741249445784,destabilizing
+TRNAU1AP,CBFA2T2,0.06853986102254453,destabilizing
+TRNAU1AP,SPDYE3,0.0956022033326463,destabilizing
+TRNAU1AP,DMD,0.1777798253757379,destabilizing
+TRNAU1AP,MCU,0.1280237162291846,destabilizing
+TRNAU1AP,SSH2,0.0827390800058691,destabilizing
+TRNAU1AP,DOCK3,0.13046795409070394,destabilizing
+TRNAU1AP,HS6ST3,0.12693876593696116,destabilizing
+TRNAU1AP,LPP,0.1411958178707146,destabilizing
+TRNAU1AP,STAG1,0.07500919796675234,destabilizing
+TRNAU1AP,CAPZA2,0.1046173495563979,destabilizing
+TRNAU1AP,ADGRL3,0.06721237486385184,destabilizing
+TRNAU1AP,UBE2R2,0.12583123417692768,destabilizing
+TRNAU1AP,GTF2IRD1,0.09267238806721043,destabilizing
+TRNAU1AP,CCBE1,0.06737731559230203,destabilizing
+TRNAU1AP,TTC28,0.09226784614091978,destabilizing
+TRNAU1AP,SBNO1,0.062136786627518946,destabilizing
+TRNAU1AP,RIMS2,0.07225800253650104,destabilizing
+TRNAU1AP,IGF1R,0.05960925686738318,destabilizing
+TRNAU1AP,TRIO,0.057371838028210005,destabilizing
+TRNAU1AP,BTBD9,0.11791329158981427,destabilizing
+TRNAU1AP,CNGB1,0.11461061871887795,destabilizing
+TRNAU1AP,FMN2,0.10596611689404187,destabilizing
+TRNAU1AP,ENSG00000228222,0.22069764859776203,destabilizing
+TRNAU1AP,PRKN,0.14399823858604655,destabilizing
+TRNAU1AP,RASA2,0.12066334784031732,destabilizing
+TRNAU1AP,PPP1R12B,0.08945491254804389,destabilizing
+TRNAU1AP,FRMD4A,0.09500689728735517,destabilizing
+TRNAU1AP,CAMK1D,0.06724862939725995,destabilizing
+TRNAU1AP,PARD3,0.05819291016859431,destabilizing
+TRNAU1AP,SEMA6D,0.10627800032606688,destabilizing
+TRNAU1AP,WIPF2,0.12545662884942263,destabilizing
+TRNAU1AP,DLEU1,0.16870160211803273,destabilizing
+TRNAU1AP,TSHZ2,0.06320236897324451,destabilizing
+TRNAU1AP,MED13L,0.0884649162685347,destabilizing
+TRNAU1AP,KAZN,0.10063277556496796,destabilizing
+TRNAU1AP,FRMD5,0.10191669444322178,destabilizing
+TRNAU1AP,LINC00174,0.11772394795262218,destabilizing
+TRNAU1AP,PPM1E,0.12227467514119536,destabilizing
+TRNAU1AP,ARL3,0.07614037409125499,destabilizing
+TRNAU1AP,MBD5,0.0739861614968768,destabilizing
+TRNAU1AP,ELAVL3,0.1008629463939182,destabilizing
+TRNAU1AP,SLIT2,0.14784554856575616,destabilizing
+TRNAU1AP,CLASP1,0.09419129809262947,destabilizing
+TRNAU1AP,UNC5C,0.13721598228158532,destabilizing
+TRNAU1AP,CACNA2D3,-0.052454057893213106,stabilizing
+TRNAU1AP,RC3H1,0.060769236393751334,destabilizing
+TRNAU1AP,NEGR1,0.1064088635386943,destabilizing
+TRNAU1AP,ENOX1,0.14892122043377093,destabilizing
+TRNAU1AP,SCUBE1,0.06048147653782498,destabilizing
+TRNAU1AP,GPHN,0.0918737601636598,destabilizing
+TRNAU1AP,NAV3,0.1227343601238272,destabilizing
+TRNAU1AP,EBF1,0.05745473948983252,destabilizing
+TRNAU1AP,TOMM22,0.1480752632877727,destabilizing
+TRNAU1AP,MAGI2,0.06278173134352999,destabilizing
+TRNAU1AP,LSAMP,0.06675636308053134,destabilizing
+TRNAU1AP,AKAP6,0.0973503904119526,destabilizing
+TRNAU1AP,TMED2,0.0819785459751849,destabilizing
+TRNAU1AP,ZBTB20,0.10708764030851034,destabilizing
+TRNAU1AP,GRIK2,0.11297928244032854,destabilizing
+TRNAU1AP,SOX5,0.06972326971205961,destabilizing
+TRNAU1AP,LRRC37A3,0.1695576125871698,destabilizing
+TRNAU1AP,EYS,0.08624585787279003,destabilizing
+TRNAU1AP,ARID1B,0.07270329776695111,destabilizing
+TRNAU1AP,PRKCE,0.06548973158902151,destabilizing
+TRNAU1AP,RBFOX1,-0.06563640579153039,stabilizing
+TRNAU1AP,SDK1,0.06818942512944767,destabilizing
+TRNAU1AP,NRG1,0.05105620885349743,destabilizing
+TRNAU1AP,MLLT3,0.1486355887863347,destabilizing
+TRNAU1AP,FMN1,0.06323581577089492,destabilizing
+TRNAU1AP,ADGRB3,0.06964014187864494,destabilizing
+TRNAU1AP,ROBO1,0.10741159932472716,destabilizing
+TRNAU1AP,SYPL1,0.06348632805683366,destabilizing
+TRNAU1AP,PTPRD,0.10698200003986837,destabilizing
+TRNAU1AP,FAM155A,0.1457714610598285,destabilizing
+TRNAU1AP,LARP1B,0.13128884696101897,destabilizing
+TNRC6A,MLLT3,0.08949517710031107,destabilizing
+TNRC6B,TRERF1,0.09922641862508713,destabilizing
+TNRC6B,SORCS1,0.08859369150040225,destabilizing
+TNRC6B,PDE3A,0.14975460826914921,destabilizing
+TNRC6B,UNC79,0.11296915629034533,destabilizing
+TNRC6B,DOC2B,0.06641912689413355,destabilizing
+TNRC6B,TMTC2,0.11985072392860997,destabilizing
+TNRC6B,CHD1,0.05479017884181307,destabilizing
+TNRC6B,PPARD,0.061934632864610976,destabilizing
+TNRC6B,MTMR7,0.09605246777069686,destabilizing
+TNRC6B,EPB41L4B,0.06815388975628307,destabilizing
+TNRC6B,CACNA1B,0.07265597753045694,destabilizing
+TNRC6B,LRRTM4,0.06530530159890073,destabilizing
+TNRC6B,PTEN,0.08851462876790987,destabilizing
+TNRC6B,FRY,0.12174834037363215,destabilizing
+TNRC6B,MACROD2,0.08800347362282775,destabilizing
+TNRC6B,SHANK2,0.14574676572859163,destabilizing
+TNRC6B,CDK12,0.1409092999292601,destabilizing
+TNRC6B,RFX7,0.12002254736141918,destabilizing
+TNRC6B,JARID2,0.06416738103049387,destabilizing
+TNRC6B,DIP2C,0.09294473915588708,destabilizing
+TNRC6B,UBR3,0.0883800059418943,destabilizing
+TNRC6B,CHST12,0.14089816598501112,destabilizing
+TNRC6B,EML5,0.1116015269926266,destabilizing
+TNRC6B,PSME4,0.11071221868386266,destabilizing
+TNRC6B,TMEM106B,0.12483316688740795,destabilizing
+TNRC6B,EPHA5,0.0672179235672457,destabilizing
+TNRC6B,KCNB2,0.09228105873490844,destabilizing
+TNRC6B,ZNF83,0.08994021899348471,destabilizing
+TNRC6B,PLEKHA5,0.06707511165293874,destabilizing
+TNRC6B,NOVA1,0.09773203843995913,destabilizing
+TNRC6B,CCNY,0.11434827433024641,destabilizing
+TNRC6B,ARIH1,0.0888643119356516,destabilizing
+TNRC6B,EPB41L5,0.0882392993459097,destabilizing
+TNRC6B,GPR158,0.11184031804087108,destabilizing
+TNRC6B,NCOA2,0.08644089404076133,destabilizing
+TNRC6B,ACACA,0.06957512216452107,destabilizing
+TNRC6B,CTNND2,0.06752500065119653,destabilizing
+TNRC6B,SIK3,0.07604238523442361,destabilizing
+TNRC6B,CPEB3,0.11677709153417225,destabilizing
+TNRC6B,CADM2,0.05849099839945896,destabilizing
+TNRC6B,XKR6,0.09574966716096729,destabilizing
+TNRC6B,TCF20,0.1112283602656933,destabilizing
+TNRC6B,DGKI,0.07628709496923765,destabilizing
+TNRC6B,EXOC6B,0.144189740403598,destabilizing
+TNRC6B,MAGI3,0.08397871251761975,destabilizing
+TNRC6B,PTPRS,0.14035495628457725,destabilizing
+TNRC6B,SPDYE3,0.09414448796044868,destabilizing
+TNRC6B,DMD,0.17353275873908353,destabilizing
+TNRC6B,MCU,0.08858331845975385,destabilizing
+TNRC6B,SSH2,0.08347987006756655,destabilizing
+TNRC6B,DOCK3,0.10453244114833132,destabilizing
+TNRC6B,HS6ST3,0.1077676572824605,destabilizing
+TNRC6B,LPP,0.12339184446300942,destabilizing
+TNRC6B,STAG1,0.09111172779628263,destabilizing
+TNRC6B,CAPZA2,0.08098736761319311,destabilizing
+TNRC6B,UBE2R2,0.10803657360340573,destabilizing
+TNRC6B,GTF2IRD1,0.09970289439611033,destabilizing
+TNRC6B,CCBE1,0.05054329199690637,destabilizing
+TNRC6B,RIMS2,0.057579704126911185,destabilizing
+TNRC6B,BTBD9,0.09167231209903215,destabilizing
+TNRC6B,CNGB1,0.1189601083139558,destabilizing
+TNRC6B,FMN2,0.09251025739340392,destabilizing
+TNRC6B,ENSG00000228222,0.11533013403399352,destabilizing
+TNRC6B,PRKN,0.1275953162329881,destabilizing
+TNRC6B,RASA2,0.09008767801533955,destabilizing
+TNRC6B,FRMD4A,0.07829001723036834,destabilizing
+TNRC6B,DLEU1,0.11524826685539331,destabilizing
+TNRC6B,TSHZ2,0.06183803418956962,destabilizing
+TNRC6B,KAZN,0.07672148342606505,destabilizing
+TNRC6B,LINC00174,0.06738572929905286,destabilizing
+TNRC6B,PPM1E,0.10210226114499002,destabilizing
+TNRC6B,MBD5,0.05991002831884405,destabilizing
+TNRC6B,ELAVL3,0.0754268421243492,destabilizing
+TNRC6B,SLIT2,0.13405461965202534,destabilizing
+TNRC6B,CLASP1,0.07640048193610592,destabilizing
+TNRC6B,UNC5C,0.10738144156008668,destabilizing
+TNRC6B,RC3H1,0.07149400136829917,destabilizing
+TNRC6B,ENOX1,0.13404147994714685,destabilizing
+TNRC6B,GPHN,0.08103893298142505,destabilizing
+TNRC6B,NAV3,0.11001189382008365,destabilizing
+TNRC6B,TOMM22,0.09780968274250705,destabilizing
+TNRC6B,AKAP6,0.07200956670910964,destabilizing
+TNRC6B,ZBTB20,0.09882357669483903,destabilizing
+TNRC6B,GRIK2,0.08175197925610371,destabilizing
+TNRC6B,LRRC37A3,0.1309648154989974,destabilizing
+TNRC6B,EYS,0.06398221053927973,destabilizing
+TNRC6B,ARID1B,0.06372069194016507,destabilizing
+TNRC6B,RBFOX1,-0.050133084610542056,stabilizing
+TNRC6B,MLLT3,0.12724740396457415,destabilizing
+TNRC6B,ROBO1,0.09696438504240935,destabilizing
+TNRC6B,SYPL1,0.06529977358194676,destabilizing
+TNRC6B,PTPRD,0.0621055661942234,destabilizing
+TNRC6B,LARP1B,0.08567031083598414,destabilizing
+TNRC6C,MLLT3,0.08057905562874654,destabilizing
+NXF1,KALRN,0.06347250694815408,destabilizing
+NXF1,MPHOSPH8,0.06792113381445772,destabilizing
+NXF1,CENPP,0.13130558488497718,destabilizing
+NXF1,IFT172,0.07692114075633887,destabilizing
+NXF1,MAGI3,0.0673464585980016,destabilizing
+NXF1,RASA2,0.07027736145207618,destabilizing
+NXF1,LINC00174,0.07388021193189274,destabilizing
+NXF1,ELAVL3,0.06436163959306977,destabilizing
+NXF1,NAV3,0.07845608873638539,destabilizing
+NXF1,MLLT3,0.1016528518249597,destabilizing
+NXF1,LARP1B,0.07412431424591745,destabilizing
+THOC5,TRERF1,0.12038351492677331,destabilizing
+THOC5,SORCS1,0.08240276713805808,destabilizing
+THOC5,COPA,0.06839120750143882,destabilizing
+THOC5,FCHSD2,0.06544227807371995,destabilizing
+THOC5,PDE3A,0.17619282175647238,destabilizing
+THOC5,UNC79,0.15156068234683023,destabilizing
+THOC5,DOC2B,0.09819427473606158,destabilizing
+THOC5,TMTC2,0.1449649565915798,destabilizing
+THOC5,KALRN,0.12587556898559335,destabilizing
+THOC5,CHD1,0.08409089015861898,destabilizing
+THOC5,PAK3,0.05315694670886751,destabilizing
+THOC5,UBE2E2,0.06593515419454193,destabilizing
+THOC5,PPARD,0.06127728783126276,destabilizing
+THOC5,BRAF,0.05153498284681204,destabilizing
+THOC5,RYR2,0.11984470849823342,destabilizing
+THOC5,MTMR7,0.15048118691098603,destabilizing
+THOC5,EIF4E,0.14043674253695798,destabilizing
+THOC5,SOX11,0.06019918957617299,destabilizing
+THOC5,EPB41L4B,0.13026215157670584,destabilizing
+THOC5,CACNA1B,0.07810984546741699,destabilizing
+THOC5,LRRTM4,0.11374232289667048,destabilizing
+THOC5,SIRPA,0.1759349896247269,destabilizing
+THOC5,PTEN,0.08869149997598551,destabilizing
+THOC5,FRY,0.14447743949759353,destabilizing
+THOC5,MACROD2,0.14115833333271638,destabilizing
+THOC5,SHANK2,0.1740171879503035,destabilizing
+THOC5,CDK12,0.17772302373081125,destabilizing
+THOC5,RFX7,0.14765109744922153,destabilizing
+THOC5,UBR5,0.0602218876528924,destabilizing
+THOC5,JARID2,0.07139741926574095,destabilizing
+THOC5,MPHOSPH8,0.09895861107133343,destabilizing
+THOC5,DIP2C,0.10038540758580995,destabilizing
+THOC5,ZNF423,0.06124716874879914,destabilizing
+THOC5,UBR3,0.10764043228200815,destabilizing
+THOC5,MGAT5,0.07621900484491717,destabilizing
+THOC5,DLG2,0.11467706618102104,destabilizing
+THOC5,CHST12,0.22551263333977722,destabilizing
+THOC5,EML5,0.1522785892221351,destabilizing
+THOC5,CENPP,0.12504184875310437,destabilizing
+THOC5,PSME4,0.12178055822490834,destabilizing
+THOC5,TMEM106B,0.1353749839369675,destabilizing
+THOC5,EPHA5,0.11827953730450942,destabilizing
+THOC5,KCNB2,0.115265441544922,destabilizing
+THOC5,ZNF83,0.0998267371532892,destabilizing
+THOC5,SOX6,0.07172570105596146,destabilizing
+THOC5,ZNF521,0.13078582402020317,destabilizing
+THOC5,PLEKHA5,0.1025943036355353,destabilizing
+THOC5,NOVA1,0.14465398850873054,destabilizing
+THOC5,CCNY,0.14268503873179292,destabilizing
+THOC5,ARIH1,0.09724284473917687,destabilizing
+THOC5,FAM171B,0.05424589788910165,destabilizing
+THOC5,EPB41L5,0.10339270706681046,destabilizing
+THOC5,GPR158,0.13465538248082323,destabilizing
+THOC5,NCOA2,0.11545286623107098,destabilizing
+THOC5,MARCKS,0.05350962164337752,destabilizing
+THOC5,ALK,0.11155878729217811,destabilizing
+THOC5,ACACA,0.08434659873014919,destabilizing
+THOC5,IFT172,0.11413905831654168,destabilizing
+THOC5,CCNT1,0.08384972528992889,destabilizing
+THOC5,DTWD2,0.15812155832841868,destabilizing
+THOC5,SIK3,0.08698401968215949,destabilizing
+THOC5,CPEB3,0.16427547874247442,destabilizing
+THOC5,CADM2,0.05683976612428711,destabilizing
+THOC5,XKR6,0.13377713834015487,destabilizing
+THOC5,CADPS,0.0633338378952088,destabilizing
+THOC5,TCF20,0.14629130405494978,destabilizing
+THOC5,CDKAL1,0.06995743014614554,destabilizing
+THOC5,DGKI,0.11491329049936456,destabilizing
+THOC5,EXOC6B,0.1851085680361855,destabilizing
+THOC5,MAGI3,0.11698804340502038,destabilizing
+THOC5,SBF2,0.06784223794670571,destabilizing
+THOC5,INPP4B,0.12727020368742065,destabilizing
+THOC5,PTPRS,0.14276923252732426,destabilizing
+THOC5,CBFA2T2,0.07389297671244278,destabilizing
+THOC5,SPDYE3,0.13169928558063893,destabilizing
+THOC5,TMEM178B,0.06618668629037283,destabilizing
+THOC5,DMD,0.19636888357786525,destabilizing
+THOC5,MCU,0.11899938106081154,destabilizing
+THOC5,SSH2,0.11450006778007826,destabilizing
+THOC5,DOCK3,0.12985870048817041,destabilizing
+THOC5,HS6ST3,0.15218689108989947,destabilizing
+THOC5,LPP,0.16454168138780967,destabilizing
+THOC5,STAG1,0.10149060292052066,destabilizing
+THOC5,CAPZA2,0.11043424599065738,destabilizing
+THOC5,ADGRL3,0.07217499373263338,destabilizing
+THOC5,UBE2R2,0.15010154996683278,destabilizing
+THOC5,GTF2IRD1,0.13718398419807562,destabilizing
+THOC5,CCBE1,0.08959895196602845,destabilizing
+THOC5,TTC28,0.10160341668726465,destabilizing
+THOC5,RIMS2,0.08676521449289148,destabilizing
+THOC5,IGF1R,0.059422354201735084,destabilizing
+THOC5,TRIO,0.07666297387824225,destabilizing
+THOC5,KCND2,0.06700598486302985,destabilizing
+THOC5,BTBD9,0.12300125417558247,destabilizing
+THOC5,CNGB1,0.14969694101004813,destabilizing
+THOC5,FMN2,0.11958850677867693,destabilizing
+THOC5,ENSG00000228222,0.19406495438032198,destabilizing
+THOC5,ATXN1,0.051714322141641,destabilizing
+THOC5,PRKN,0.16529387584615124,destabilizing
+THOC5,RASA2,0.1318639663287931,destabilizing
+THOC5,PPP1R12B,0.08820494926878207,destabilizing
+THOC5,FRMD4A,0.10007790893736068,destabilizing
+THOC5,CAMK1D,0.06201353688487887,destabilizing
+THOC5,SEMA6D,0.10223118528138783,destabilizing
+THOC5,WIPF2,0.13159201313162966,destabilizing
+THOC5,DLEU1,0.18443161230715477,destabilizing
+THOC5,TSHZ2,0.08145627389629222,destabilizing
+THOC5,MED13L,0.06397073916773588,destabilizing
+THOC5,KAZN,0.10347502774867659,destabilizing
+THOC5,KANSL1,0.07461770721403868,destabilizing
+THOC5,FRMD5,0.09197879172526463,destabilizing
+THOC5,LINC00174,0.1117634224301889,destabilizing
+THOC5,PPM1E,0.13128551204711697,destabilizing
+THOC5,ARL3,0.07980650034694792,destabilizing
+THOC5,MBD5,0.11823965583232243,destabilizing
+THOC5,ELAVL3,0.12106220658587133,destabilizing
+THOC5,SLIT2,0.1621650406744619,destabilizing
+THOC5,CLASP1,0.0830541503638773,destabilizing
+THOC5,UNC5C,0.11544806472480855,destabilizing
+THOC5,RC3H1,0.08841809239028009,destabilizing
+THOC5,NEGR1,0.13129342291759052,destabilizing
+THOC5,ENOX1,0.17396650700255586,destabilizing
+THOC5,SCUBE1,0.08228854706870259,destabilizing
+THOC5,GPHN,0.11105560511300319,destabilizing
+THOC5,NAV3,0.1561324432728495,destabilizing
+THOC5,EBF1,0.05462334814306504,destabilizing
+THOC5,TOMM22,0.12318100641606604,destabilizing
+THOC5,MAGI2,0.08936987716049638,destabilizing
+THOC5,LSAMP,0.09619234134491783,destabilizing
+THOC5,AKAP6,0.1222724089533296,destabilizing
+THOC5,TMED2,0.10782274773529595,destabilizing
+THOC5,ZBTB20,0.08307287328387793,destabilizing
+THOC5,GRIK2,0.13094493649483993,destabilizing
+THOC5,SOX5,0.08703700107551908,destabilizing
+THOC5,LRRC37A3,0.16232244833674253,destabilizing
+THOC5,EYS,0.08819727568529853,destabilizing
+THOC5,ARID1B,0.06880815332686047,destabilizing
+THOC5,PRKCE,0.08782154883537578,destabilizing
+THOC5,RBFOX1,-0.06105878389020591,stabilizing
+THOC5,SDK1,0.07753429203393647,destabilizing
+THOC5,NRG1,0.05503729024842751,destabilizing
+THOC5,MLLT3,0.1790064300053162,destabilizing
+THOC5,FMN1,0.07769209340752949,destabilizing
+THOC5,ADGRB3,0.10017924063942638,destabilizing
+THOC5,ROBO1,0.15416193788387714,destabilizing
+THOC5,SYPL1,0.07330645547970963,destabilizing
+THOC5,PTPRD,0.11283758721085511,destabilizing
+THOC5,FAM155A,0.15154347846878494,destabilizing
+THOC5,LARP1B,0.13836174861782424,destabilizing
+SMNDC1,DMD,0.08290016258189586,destabilizing
+SNRPA,TRERF1,0.12773439293142183,destabilizing
+SNRPA,SORCS1,0.07868632217074355,destabilizing
+SNRPA,PDE3A,0.1108440093797601,destabilizing
+SNRPA,UNC79,0.15554524649337886,destabilizing
+SNRPA,DOC2B,0.08168330151291889,destabilizing
+SNRPA,TMTC2,0.12980531164936607,destabilizing
+SNRPA,UBE2E2,0.05914669603872723,destabilizing
+SNRPA,TOX,0.08241392354574324,destabilizing
+SNRPA,RYR2,0.15707222451438663,destabilizing
+SNRPA,MTMR7,0.13568671198048451,destabilizing
+SNRPA,EIF4E,0.13111693913141786,destabilizing
+SNRPA,EPB41L4B,0.060243371172296174,destabilizing
+SNRPA,CACNA1B,0.07299428117472818,destabilizing
+SNRPA,WSB1,0.06465456664776448,destabilizing
+SNRPA,PTEN,0.07348718202737105,destabilizing
+SNRPA,FRY,0.18607336008542874,destabilizing
+SNRPA,RUNX1T1,0.06457729268066893,destabilizing
+SNRPA,MACROD2,0.1059636380399917,destabilizing
+SNRPA,SHANK2,0.10736872250360646,destabilizing
+SNRPA,CDK12,0.1700404272968226,destabilizing
+SNRPA,RFX7,0.12194986156258629,destabilizing
+SNRPA,MPHOSPH8,0.10218063118737401,destabilizing
+SNRPA,ZNF423,0.06131976384042798,destabilizing
+SNRPA,DLG2,0.08094256806371795,destabilizing
+SNRPA,CHST12,0.1791541450681661,destabilizing
+SNRPA,EML5,0.14168561446841402,destabilizing
+SNRPA,CENPP,0.20540832418882232,destabilizing
+SNRPA,PSME4,0.08054410140454837,destabilizing
+SNRPA,TMEM106B,0.10099642375387956,destabilizing
+SNRPA,EPHA5,0.08378290436442058,destabilizing
+SNRPA,KCNB2,0.18226051290237577,destabilizing
+SNRPA,ZNF83,0.07473586159045605,destabilizing
+SNRPA,SOX6,0.09562300674480792,destabilizing
+SNRPA,ZNF521,0.09296065532553952,destabilizing
+SNRPA,PLEKHA5,0.07710901706660098,destabilizing
+SNRPA,NOVA1,0.15177942385779478,destabilizing
+SNRPA,CCNY,0.11111114118404015,destabilizing
+SNRPA,ARIH1,0.07308923387091422,destabilizing
+SNRPA,GPR158,0.12286154705529057,destabilizing
+SNRPA,NCOA2,0.07533015384991112,destabilizing
+SNRPA,ALK,0.19339086599910418,destabilizing
+SNRPA,IFT172,0.11757000557592326,destabilizing
+SNRPA,CCNT1,0.06410406085791454,destabilizing
+SNRPA,DTWD2,0.23174684581944716,destabilizing
+SNRPA,SIK3,0.10980208650590693,destabilizing
+SNRPA,CPEB3,0.1068107843902307,destabilizing
+SNRPA,XKR6,0.1167029862257898,destabilizing
+SNRPA,CADPS,0.0776944307234168,destabilizing
+SNRPA,FGF13,0.07516882983619406,destabilizing
+SNRPA,TCF20,0.08647980768655439,destabilizing
+SNRPA,CDKAL1,0.08780499194988738,destabilizing
+SNRPA,DGKI,0.10611479248762232,destabilizing
+SNRPA,EXOC6B,0.12712082751413809,destabilizing
+SNRPA,MAGI3,0.1226184297412996,destabilizing
+SNRPA,SBF2,0.05934323323222242,destabilizing
+SNRPA,INPP4B,0.07158441932930558,destabilizing
+SNRPA,DMD,0.1451950564222327,destabilizing
+SNRPA,MCU,0.09972445717348766,destabilizing
+SNRPA,SSH2,0.09034013967038287,destabilizing
+SNRPA,DOCK3,0.11560411092571429,destabilizing
+SNRPA,LPP,0.09429725206592816,destabilizing
+SNRPA,STAG1,0.07896803012288481,destabilizing
+SNRPA,CAPZA2,0.12639891431840608,destabilizing
+SNRPA,PHACTR1,0.093528209016097,destabilizing
+SNRPA,RIMS2,0.079442749895609,destabilizing
+SNRPA,BTBD9,0.08146437350449863,destabilizing
+SNRPA,CNGB1,0.129363917116168,destabilizing
+SNRPA,FMN2,0.07561675539759477,destabilizing
+SNRPA,ENSG00000228222,0.1740907681793337,destabilizing
+SNRPA,ATXN1,0.05642560016664205,destabilizing
+SNRPA,SYN3,0.061952327067756004,destabilizing
+SNRPA,PRKN,0.1043079852001751,destabilizing
+SNRPA,RASA2,0.13940880535326983,destabilizing
+SNRPA,PPP1R12B,0.0851076637580959,destabilizing
+SNRPA,FRMD4A,0.0639480911127492,destabilizing
+SNRPA,SEMA6D,0.09274524480341244,destabilizing
+SNRPA,WIPF2,0.11471599856792244,destabilizing
+SNRPA,DLEU1,0.1345012937736065,destabilizing
+SNRPA,TSHZ2,0.06861358329685355,destabilizing
+SNRPA,MED13L,0.06716815151145725,destabilizing
+SNRPA,KAZN,0.08110303369278414,destabilizing
+SNRPA,KANSL1,0.08684202336238023,destabilizing
+SNRPA,FRMD5,0.07397296399862245,destabilizing
+SNRPA,LINC00174,0.12995276327378152,destabilizing
+SNRPA,ARL3,0.08626731280101266,destabilizing
+SNRPA,MBD5,0.09074102607552656,destabilizing
+SNRPA,ELAVL3,0.0888288315696001,destabilizing
+SNRPA,SLIT2,0.09293555770878933,destabilizing
+SNRPA,CLASP1,0.08486007092685706,destabilizing
+SNRPA,UNC5C,0.09893023721269843,destabilizing
+SNRPA,NEGR1,0.10836045922726377,destabilizing
+SNRPA,ENOX1,0.15983547119298525,destabilizing
+SNRPA,NAV3,0.09184583784529153,destabilizing
+SNRPA,TOMM22,0.1382305060356114,destabilizing
+SNRPA,MBNL2,0.056134691602143454,destabilizing
+SNRPA,ANKFN1,0.05430450206505755,destabilizing
+SNRPA,LSAMP,0.05571194921965033,destabilizing
+SNRPA,AKAP6,0.08886825629738067,destabilizing
+SNRPA,TMED2,0.06509913483507272,destabilizing
+SNRPA,ZBTB20,0.13876223618295366,destabilizing
+SNRPA,GRIK2,0.09486955627165165,destabilizing
+SNRPA,SOX5,0.07172339983251817,destabilizing
+SNRPA,LRRC37A3,0.11708021735282373,destabilizing
+SNRPA,EYS,0.07463910188951246,destabilizing
+SNRPA,ARID1B,0.05997556060537009,destabilizing
+SNRPA,PRKCE,0.0663151988841214,destabilizing
+SNRPA,MLLT3,0.17900554151696102,destabilizing
+SNRPA,SYPL1,0.06347940548166962,destabilizing
+SNRPA,PTPRD,0.06683638664997162,destabilizing
+SNRPA,FAM155A,0.13046052516892126,destabilizing
+SNRPA,LARP1B,0.09258158390852897,destabilizing
+G3BP1,TMTC2,0.08448439065921587,destabilizing
+G3BP1,EIF4E,0.10752005554759624,destabilizing
+G3BP1,MACROD2,0.08383916080685758,destabilizing
+G3BP1,CDK12,0.09832664664611374,destabilizing
+G3BP1,CENPP,0.1533857646489899,destabilizing
+G3BP1,KCNB2,0.11423755047206428,destabilizing
+G3BP1,SOX6,0.060560810112937416,destabilizing
+G3BP1,ALK,0.11346989760428641,destabilizing
+G3BP1,CCNT1,0.059683600431453446,destabilizing
+G3BP1,XKR6,0.07138956069092622,destabilizing
+G3BP1,MAGI3,0.07220542035885247,destabilizing
+G3BP1,DMD,0.11525482460353546,destabilizing
+G3BP1,RASA2,0.08563761254928216,destabilizing
+G3BP1,FRMD5,0.07760695212373059,destabilizing
+G3BP1,ELAVL3,0.06420011353215063,destabilizing
+G3BP1,UNC5C,0.07347491872761386,destabilizing
+G3BP1,NEGR1,0.10138419456518566,destabilizing
+G3BP1,LRRC37A3,0.0770706647638719,destabilizing
+G3BP1,MLLT3,0.1102358580566301,destabilizing
+G3BP1,SYPL1,0.052039213379774296,destabilizing
+G3BP2,TRERF1,0.09880469727020261,destabilizing
+G3BP2,SORCS1,0.0820615528618231,destabilizing
+G3BP2,UNC79,0.0947852699382593,destabilizing
+G3BP2,DOC2B,0.0726605307919794,destabilizing
+G3BP2,CHD1,0.07371829521268428,destabilizing
+G3BP2,EPB41L4B,0.08019497585536221,destabilizing
+G3BP2,CACNA1B,0.08799849962685065,destabilizing
+G3BP2,LRRTM4,0.06824831409579821,destabilizing
+G3BP2,FRY,0.09233969547912875,destabilizing
+G3BP2,MACROD2,0.08709268217792426,destabilizing
+G3BP2,SHANK2,0.11964216733912263,destabilizing
+G3BP2,CDK12,0.13058710001654136,destabilizing
+G3BP2,MPHOSPH8,0.09029086284161172,destabilizing
+G3BP2,DLG2,0.06060301359509565,destabilizing
+G3BP2,CHST12,0.16246484068347142,destabilizing
+G3BP2,EML5,0.11675285154062552,destabilizing
+G3BP2,PSME4,0.11369066770501844,destabilizing
+G3BP2,TMEM106B,0.11048434217375326,destabilizing
+G3BP2,ZNF83,0.0932451874796632,destabilizing
+G3BP2,SOX6,0.06044808880562346,destabilizing
+G3BP2,NOVA1,0.12921253744106045,destabilizing
+G3BP2,CCNY,0.09969453414008629,destabilizing
+G3BP2,ALK,0.11155579007228644,destabilizing
+G3BP2,IFT172,0.09537969712281898,destabilizing
+G3BP2,CADM2,0.06589909927417999,destabilizing
+G3BP2,XKR6,0.10428260032649138,destabilizing
+G3BP2,TCF20,0.08736809713031804,destabilizing
+G3BP2,CDKAL1,0.07771292259947409,destabilizing
+G3BP2,DGKI,0.07012475285680468,destabilizing
+G3BP2,EXOC6B,0.08843929206967464,destabilizing
+G3BP2,MAGI3,0.08776346810053728,destabilizing
+G3BP2,SBF2,0.06536778577738117,destabilizing
+G3BP2,INPP4B,0.08895116039348622,destabilizing
+G3BP2,DMD,0.15247529870663307,destabilizing
+G3BP2,SSH2,0.06475214867617453,destabilizing
+G3BP2,DOCK3,0.11933477276401702,destabilizing
+G3BP2,HS6ST3,0.10290787293333896,destabilizing
+G3BP2,LPP,0.10457565207518321,destabilizing
+G3BP2,STAG1,0.08976394704653165,destabilizing
+G3BP2,CAPZA2,0.06829650218335183,destabilizing
+G3BP2,UBE2R2,0.09481206585485187,destabilizing
+G3BP2,GTF2IRD1,0.06488790106773548,destabilizing
+G3BP2,BTBD9,0.08670278224816992,destabilizing
+G3BP2,CNGB1,0.11728695473318354,destabilizing
+G3BP2,FMN2,0.06569615449946654,destabilizing
+G3BP2,ENSG00000228222,0.11549130604984889,destabilizing
+G3BP2,PRKN,0.11344892708741243,destabilizing
+G3BP2,RASA2,0.09531552136107653,destabilizing
+G3BP2,FRMD4A,0.0708863813041096,destabilizing
+G3BP2,SEMA6D,0.08114391489949732,destabilizing
+G3BP2,WIPF2,0.09482954276121354,destabilizing
+G3BP2,DLEU1,0.11807095234348307,destabilizing
+G3BP2,TSHZ2,0.06323954287837939,destabilizing
+G3BP2,FRMD5,0.08895965162931746,destabilizing
+G3BP2,LINC00174,0.08919298031958099,destabilizing
+G3BP2,PPM1E,0.0893064042377258,destabilizing
+G3BP2,MBD5,0.07441308237144109,destabilizing
+G3BP2,ELAVL3,0.09564028054728702,destabilizing
+G3BP2,SLIT2,0.12557869199579252,destabilizing
+G3BP2,NEGR1,0.08943296634579509,destabilizing
+G3BP2,ENOX1,0.1205690373980286,destabilizing
+G3BP2,GPHN,0.06687138772149137,destabilizing
+G3BP2,NAV3,0.08659585979033653,destabilizing
+G3BP2,TOMM22,0.12113269095246518,destabilizing
+G3BP2,LSAMP,0.06656540220698812,destabilizing
+G3BP2,AKAP6,0.07965344403270265,destabilizing
+G3BP2,TMED2,0.07734818681707838,destabilizing
+G3BP2,ZBTB20,0.07889874292146493,destabilizing
+G3BP2,GRIK2,0.09164775511861717,destabilizing
+G3BP2,LRRC37A3,0.1305903454355005,destabilizing
+G3BP2,EYS,0.05802949190041661,destabilizing
+G3BP2,ARID1B,0.0670607254402868,destabilizing
+G3BP2,RBFOX1,-0.051863111412312944,stabilizing
+G3BP2,MLLT3,0.13551412002314733,destabilizing
+G3BP2,ADGRB3,0.06959818764041345,destabilizing
+G3BP2,ROBO1,0.09086950698954196,destabilizing
+G3BP2,PTPRD,0.07475299397257547,destabilizing
+G3BP2,FAM155A,0.10176516056862926,destabilizing
+G3BP2,LARP1B,0.07475419023528437,destabilizing
+PRKRA,TRERF1,0.1428399320008667,destabilizing
+PRKRA,SORCS1,0.07129911426558534,destabilizing
+PRKRA,NCOA1,0.05792078927619991,destabilizing
+PRKRA,COPA,0.05816870091507331,destabilizing
+PRKRA,PDE3A,0.1390054642418781,destabilizing
+PRKRA,UNC79,0.12856196321880212,destabilizing
+PRKRA,DOC2B,0.0937493530707188,destabilizing
+PRKRA,TMTC2,0.10728767486034835,destabilizing
+PRKRA,KALRN,0.07701836097497164,destabilizing
+PRKRA,CHD1,0.07850342957282766,destabilizing
+PRKRA,UBE2E2,0.059900943503250405,destabilizing
+PRKRA,PPARD,0.08144553869641809,destabilizing
+PRKRA,RYR2,0.12038189814222552,destabilizing
+PRKRA,MTMR7,0.15535195399730745,destabilizing
+PRKRA,EPB41L4B,0.08542797569559477,destabilizing
+PRKRA,CACNA1B,0.08939275770816053,destabilizing
+PRKRA,LRRTM4,0.06755558660641402,destabilizing
+PRKRA,FRY,0.15125901744413334,destabilizing
+PRKRA,MACROD2,0.11382851223958179,destabilizing
+PRKRA,SHANK2,0.1629765417634063,destabilizing
+PRKRA,CDK12,0.17160367578153096,destabilizing
+PRKRA,RFX7,0.10333575793736505,destabilizing
+PRKRA,MPHOSPH8,0.10086285246472862,destabilizing
+PRKRA,DIP2C,0.10228004686257221,destabilizing
+PRKRA,UBR3,0.07436737586406415,destabilizing
+PRKRA,DLG2,0.08760544931191538,destabilizing
+PRKRA,CHST12,0.21113025773095978,destabilizing
+PRKRA,EML5,0.11497663680907716,destabilizing
+PRKRA,CENPP,0.186470704314149,destabilizing
+PRKRA,PSME4,0.12218342212081598,destabilizing
+PRKRA,TMEM106B,0.11604445427456989,destabilizing
+PRKRA,EPHA5,0.08550258363027584,destabilizing
+PRKRA,KCNB2,0.15586068746460574,destabilizing
+PRKRA,ZNF83,0.09286882103066206,destabilizing
+PRKRA,SOX6,0.10044163803003717,destabilizing
+PRKRA,ZNF521,0.10183359910259573,destabilizing
+PRKRA,PLEKHA5,0.08114184758777304,destabilizing
+PRKRA,NOVA1,0.14290497652815437,destabilizing
+PRKRA,CCNY,0.11594718430379282,destabilizing
+PRKRA,ARIH1,0.11960545318782398,destabilizing
+PRKRA,EPB41L5,0.08075288510969325,destabilizing
+PRKRA,GPR158,0.11517276705698315,destabilizing
+PRKRA,NCOA2,0.09131839141987025,destabilizing
+PRKRA,ALK,0.10540857270886027,destabilizing
+PRKRA,IFT172,0.1210512632504714,destabilizing
+PRKRA,CCNT1,0.07981215187081236,destabilizing
+PRKRA,DTWD2,0.1850743736917743,destabilizing
+PRKRA,SIK3,0.11613233257150601,destabilizing
+PRKRA,CPEB3,0.14480772522221885,destabilizing
+PRKRA,CADM2,0.05949958286679086,destabilizing
+PRKRA,XKR6,0.11035601999203262,destabilizing
+PRKRA,TCF20,0.0874867291213015,destabilizing
+PRKRA,DGKI,0.09037180343027047,destabilizing
+PRKRA,EXOC6B,0.1496173332745234,destabilizing
+PRKRA,MAGI3,0.1254880232085282,destabilizing
+PRKRA,SBF2,0.0663372315929845,destabilizing
+PRKRA,INPP4B,0.10319573646625887,destabilizing
+PRKRA,CBFA2T2,0.07347702841729434,destabilizing
+PRKRA,SPDYE3,0.11225899941988782,destabilizing
+PRKRA,DMD,0.16760244652157275,destabilizing
+PRKRA,EIF4G3,0.05796158604556927,destabilizing
+PRKRA,MCU,0.07900791709018695,destabilizing
+PRKRA,SSH2,0.08404200623683687,destabilizing
+PRKRA,DOCK3,0.13649449396195334,destabilizing
+PRKRA,HS6ST3,0.11840956720941063,destabilizing
+PRKRA,LPP,0.13673959099736263,destabilizing
+PRKRA,STAG1,0.09756946510545572,destabilizing
+PRKRA,CAPZA2,0.10123309573311812,destabilizing
+PRKRA,UBE2R2,0.09408538958146845,destabilizing
+PRKRA,GTF2IRD1,0.0982204863011929,destabilizing
+PRKRA,SBNO1,0.06708197331851273,destabilizing
+PRKRA,RIMS2,0.0889044514480288,destabilizing
+PRKRA,BTBD9,0.10715592147045173,destabilizing
+PRKRA,CNGB1,0.12173426357038794,destabilizing
+PRKRA,FMN2,0.09267270925626359,destabilizing
+PRKRA,ENSG00000228222,0.1856307996618266,destabilizing
+PRKRA,PRKN,0.12870214593398677,destabilizing
+PRKRA,RASA2,0.12574999579743631,destabilizing
+PRKRA,PPP1R12B,0.07368328970515105,destabilizing
+PRKRA,FRMD4A,0.10422412806382145,destabilizing
+PRKRA,CAMK1D,0.06278740104165095,destabilizing
+PRKRA,SEMA6D,0.11617588840235703,destabilizing
+PRKRA,WIPF2,0.11436528165821612,destabilizing
+PRKRA,DLEU1,0.15222659860752435,destabilizing
+PRKRA,TSHZ2,0.07066278835073546,destabilizing
+PRKRA,MED13L,0.07142335246608777,destabilizing
+PRKRA,KAZN,0.09608964826864141,destabilizing
+PRKRA,KANSL1,0.0645195822237056,destabilizing
+PRKRA,FRMD5,0.06833031286236978,destabilizing
+PRKRA,LINC00174,0.10623245822217033,destabilizing
+PRKRA,PPM1E,0.092920934721438,destabilizing
+PRKRA,ARL3,0.08431795379399563,destabilizing
+PRKRA,MBD5,0.09238064152699245,destabilizing
+PRKRA,ELAVL3,0.11022475371889569,destabilizing
+PRKRA,SLIT2,0.1296180913911479,destabilizing
+PRKRA,CLASP1,0.09940606472940218,destabilizing
+PRKRA,UNC5C,0.09245393778217204,destabilizing
+PRKRA,RC3H1,0.08353359264600248,destabilizing
+PRKRA,NEGR1,0.10308442301648828,destabilizing
+PRKRA,ENOX1,0.14274344337944486,destabilizing
+PRKRA,SCUBE1,0.0775668942768454,destabilizing
+PRKRA,GPHN,0.0855760661298192,destabilizing
+PRKRA,NAV3,0.12265793756478148,destabilizing
+PRKRA,TOMM22,0.12583779471488274,destabilizing
+PRKRA,MBNL2,0.05806057368708686,destabilizing
+PRKRA,MAGI2,0.05319018983544368,destabilizing
+PRKRA,LSAMP,0.056584922053023026,destabilizing
+PRKRA,AKAP6,0.11369680581893249,destabilizing
+PRKRA,TMED2,0.08945690522119308,destabilizing
+PRKRA,ZBTB20,0.10766865537564027,destabilizing
+PRKRA,GRIK2,0.10799609729660332,destabilizing
+PRKRA,SOX5,0.08343314495027639,destabilizing
+PRKRA,LRRC37A3,0.14957920811304162,destabilizing
+PRKRA,EYS,0.08331603176903578,destabilizing
+PRKRA,PRKCE,0.09517748698488841,destabilizing
+PRKRA,RBFOX1,-0.06526074870493202,stabilizing
+PRKRA,NRG1,0.06300950417069008,destabilizing
+PRKRA,MLLT3,0.17013581876764508,destabilizing
+PRKRA,FMN1,0.05543389262511254,destabilizing
+PRKRA,ROBO1,0.10331690606425435,destabilizing
+PRKRA,SYPL1,0.09781434803664932,destabilizing
+PRKRA,PTPRD,0.10036166772551944,destabilizing
+PRKRA,FAM155A,0.13728111790750117,destabilizing
+PRKRA,LARP1B,0.09140269172676918,destabilizing
diff --git a/output/tier3/results/neuroblastoma_results.json b/output/tier3/results/neuroblastoma_results.json
new file mode 100644
index 0000000000000000000000000000000000000000..4693a5096db6db3c644981ff34dc25c40731d23c
--- /dev/null
+++ b/output/tier3/results/neuroblastoma_results.json
@@ -0,0 +1,33 @@
+{
+ "n_cells": 9398,
+ "n_genes": 9669,
+ "n_informative": 8034,
+ "frac_informative": 0.830902885510394,
+ "halflife_mouse_r": -0.05974277831801158,
+ "halflife_mouse_p": 1.7258243270843862e-06,
+ "halflife_mouse_n": 6401,
+ "halflife_human_r": -0.050262831877632384,
+ "halflife_human_p": 3.516124213633178e-05,
+ "halflife_human_n": 6769,
+ "best_k": 2,
+ "best_silhouette": 0.18800485134124756,
+ "expr_silhouette": 0.294854998588562,
+ "invisibility": -0.10685014724731445,
+ "n_diff_genes": 7584,
+ "n_raw_edges": 9112,
+ "raw_destab_frac": 0.9885864793678666,
+ "n_network_edges": 326,
+ "corrected_destab_frac": 0.3374233128834356,
+ "top_hubs": {
+ "HNRNPA2B1": 46,
+ "PABPC1": 28,
+ "YBX1": 21,
+ "HNRNPD": 18,
+ "HNRNPU": 18,
+ "PRPF8": 17,
+ "SNRNP200": 16,
+ "FUS": 14,
+ "HNRNPK": 14,
+ "NCL": 12
+ }
+}
\ No newline at end of file
diff --git a/output/tier3/results/neuroblastoma_stability_programs.csv b/output/tier3/results/neuroblastoma_stability_programs.csv
new file mode 100644
index 0000000000000000000000000000000000000000..63516f1dbc1dda40e38708d551cccfa1b5a33974
--- /dev/null
+++ b/output/tier3/results/neuroblastoma_stability_programs.csv
@@ -0,0 +1,2 @@
+cluster,direction,pathway,fdr,n_overlap
+GC_0,up_degraded,Protein Modification Process (GO:0036211),0.0036573435480566,22/711
diff --git a/output/weakness_fixes/figures/destabilizing_bias_fix_dentate_gyrus.png b/output/weakness_fixes/figures/destabilizing_bias_fix_dentate_gyrus.png
new file mode 100644
index 0000000000000000000000000000000000000000..00c57c0582cd15c15a081f67055f4ad669142e35
Binary files /dev/null and b/output/weakness_fixes/figures/destabilizing_bias_fix_dentate_gyrus.png differ
diff --git a/output/weakness_fixes/figures/eclip_validation_fix.png b/output/weakness_fixes/figures/eclip_validation_fix.png
new file mode 100644
index 0000000000000000000000000000000000000000..723557394b413357b4e449a838378aad7989faf1
Binary files /dev/null and b/output/weakness_fixes/figures/eclip_validation_fix.png differ
diff --git a/output/weakness_fixes/results/consistency_fix.json b/output/weakness_fixes/results/consistency_fix.json
new file mode 100644
index 0000000000000000000000000000000000000000..eb0a5140f93102287a3baa6a9ae6080ef1d3b393
--- /dev/null
+++ b/output/weakness_fixes/results/consistency_fix.json
@@ -0,0 +1,20 @@
+[
+ {
+ "pair": "dentate_gyrus vs pancreas",
+ "gamma_r_all": 0.1915326245338796,
+ "expr_r_all": 0.630208533589135,
+ "n_shared": 4915
+ },
+ {
+ "pair": "dentate_gyrus vs scifate",
+ "gamma_r_all": 0.08447339384620146,
+ "expr_r_all": 0.3197348140200488,
+ "n_shared": 3382
+ },
+ {
+ "pair": "pancreas vs scifate",
+ "gamma_r_all": 0.27801667286917026,
+ "expr_r_all": 0.35574261904050636,
+ "n_shared": 6444
+ }
+]
\ No newline at end of file
diff --git a/output/weakness_fixes/results/eclip_fix.json b/output/weakness_fixes/results/eclip_fix.json
new file mode 100644
index 0000000000000000000000000000000000000000..be16c8943711f1990c9cac807912042779529832
--- /dev/null
+++ b/output/weakness_fixes/results/eclip_fix.json
@@ -0,0 +1,256 @@
+[
+ {
+ "dataset": "pancreas",
+ "per_rbp": [
+ {
+ "rbp": "ELAVL1",
+ "type": "ubiquitous",
+ "n_predicted": 7,
+ "n_eclip": 2326,
+ "overlap": 2,
+ "odds_ratio": 1.6480206540447504,
+ "p_value": 0.41050616258767086,
+ "dataset": "pancreas"
+ },
+ {
+ "rbp": "FUS",
+ "type": "ubiquitous",
+ "n_predicted": 16,
+ "n_eclip": 811,
+ "overlap": 2,
+ "odds_ratio": 1.9567367119901113,
+ "p_value": 0.2983084251649545,
+ "dataset": "pancreas"
+ },
+ {
+ "rbp": "HNRNPA1",
+ "type": "ubiquitous",
+ "n_predicted": 102,
+ "n_eclip": 154,
+ "overlap": 3,
+ "odds_ratio": 2.3385510736504114,
+ "p_value": 0.14562642685524352,
+ "dataset": "pancreas"
+ },
+ {
+ "rbp": "HNRNPC",
+ "type": "ubiquitous",
+ "n_predicted": 19,
+ "n_eclip": 1386,
+ "overlap": 6,
+ "odds_ratio": 3.514046822742475,
+ "p_value": 0.017506984462539284,
+ "dataset": "pancreas"
+ },
+ {
+ "rbp": "HNRNPU",
+ "type": "ubiquitous",
+ "n_predicted": 2,
+ "n_eclip": 221,
+ "overlap": 0,
+ "odds_ratio": 0.0,
+ "p_value": 1.0,
+ "dataset": "pancreas"
+ },
+ {
+ "rbp": "MATR3",
+ "type": "ubiquitous",
+ "n_predicted": 1,
+ "n_eclip": 1656,
+ "overlap": 1,
+ "odds_ratio": Infinity,
+ "p_value": 0.1390895346883924,
+ "dataset": "pancreas"
+ },
+ {
+ "rbp": "MBNL2",
+ "type": "cell-specific",
+ "n_predicted": 40,
+ "n_eclip": 414,
+ "overlap": 0,
+ "odds_ratio": 0.0,
+ "p_value": 1.0,
+ "dataset": "pancreas"
+ },
+ {
+ "rbp": "RBFOX2",
+ "type": "cell-specific",
+ "n_predicted": 13,
+ "n_eclip": 2075,
+ "overlap": 3,
+ "odds_ratio": 1.4219594594594596,
+ "p_value": 0.4012260216140694,
+ "dataset": "pancreas"
+ },
+ {
+ "rbp": "TRA2B",
+ "type": "cell-specific",
+ "n_predicted": 4,
+ "n_eclip": 636,
+ "overlap": 0,
+ "odds_ratio": 0.0,
+ "p_value": 1.0,
+ "dataset": "pancreas"
+ }
+ ],
+ "aggregate_or": 1.3031897149871905,
+ "aggregate_p": 0.09035501130039116,
+ "aggregate_enrichment": 1.1611675689478154
+ },
+ {
+ "dataset": "dentate_gyrus",
+ "per_rbp": [
+ {
+ "rbp": "ELAVL1",
+ "type": "ubiquitous",
+ "n_predicted": 1,
+ "n_eclip": 1267,
+ "overlap": 0,
+ "odds_ratio": 0.0,
+ "p_value": 1.0,
+ "dataset": "dentate_gyrus"
+ },
+ {
+ "rbp": "HNRNPA1",
+ "type": "ubiquitous",
+ "n_predicted": 55,
+ "n_eclip": 74,
+ "overlap": 3,
+ "odds_ratio": 4.22453954496208,
+ "p_value": 0.040382945154632,
+ "dataset": "dentate_gyrus"
+ },
+ {
+ "rbp": "HNRNPC",
+ "type": "ubiquitous",
+ "n_predicted": 14,
+ "n_eclip": 750,
+ "overlap": 3,
+ "odds_ratio": 1.6663015699160277,
+ "p_value": 0.3145056465568202,
+ "dataset": "dentate_gyrus"
+ },
+ {
+ "rbp": "MBNL2",
+ "type": "cell-specific",
+ "n_predicted": 27,
+ "n_eclip": 196,
+ "overlap": 1,
+ "odds_ratio": 1.006508875739645,
+ "p_value": 0.6376271174105022,
+ "dataset": "dentate_gyrus"
+ },
+ {
+ "rbp": "RBFOX2",
+ "type": "cell-specific",
+ "n_predicted": 15,
+ "n_eclip": 949,
+ "overlap": 3,
+ "odds_ratio": 1.153276955602537,
+ "p_value": 0.5163138554773509,
+ "dataset": "dentate_gyrus"
+ }
+ ],
+ "aggregate_or": 0.7829419007399054,
+ "aggregate_p": 0.8523723011463239,
+ "aggregate_enrichment": 0.8556638712047013
+ },
+ {
+ "dataset": "scifate",
+ "per_rbp": [
+ {
+ "rbp": "ELAVL1",
+ "type": "ubiquitous",
+ "n_predicted": 3,
+ "n_eclip": 2274,
+ "overlap": 1,
+ "odds_ratio": 1.2525296964364276,
+ "p_value": 0.6350194693967628,
+ "dataset": "scifate"
+ },
+ {
+ "rbp": "FUS",
+ "type": "ubiquitous",
+ "n_predicted": 68,
+ "n_eclip": 738,
+ "overlap": 5,
+ "odds_ratio": 0.7762186275146712,
+ "p_value": 0.7672683197329379,
+ "dataset": "scifate"
+ },
+ {
+ "rbp": "HNRNPA1",
+ "type": "ubiquitous",
+ "n_predicted": 80,
+ "n_eclip": 145,
+ "overlap": 0,
+ "odds_ratio": 0.0,
+ "p_value": 1.0,
+ "dataset": "scifate"
+ },
+ {
+ "rbp": "HNRNPC",
+ "type": "ubiquitous",
+ "n_predicted": 11,
+ "n_eclip": 1321,
+ "overlap": 1,
+ "odds_ratio": 0.5029545454545454,
+ "p_value": 0.8639551470798073,
+ "dataset": "scifate"
+ },
+ {
+ "rbp": "HNRNPU",
+ "type": "ubiquitous",
+ "n_predicted": 41,
+ "n_eclip": 183,
+ "overlap": 0,
+ "odds_ratio": 0.0,
+ "p_value": 1.0,
+ "dataset": "scifate"
+ },
+ {
+ "rbp": "MATR3",
+ "type": "ubiquitous",
+ "n_predicted": 74,
+ "n_eclip": 1551,
+ "overlap": 9,
+ "odds_ratio": 0.5705477401975456,
+ "p_value": 0.9655076997175472,
+ "dataset": "scifate"
+ },
+ {
+ "rbp": "MBNL2",
+ "type": "cell-specific",
+ "n_predicted": 37,
+ "n_eclip": 358,
+ "overlap": 1,
+ "odds_ratio": 0.5894802365390601,
+ "p_value": 0.8181200632699638,
+ "dataset": "scifate"
+ },
+ {
+ "rbp": "RBFOX2",
+ "type": "cell-specific",
+ "n_predicted": 130,
+ "n_eclip": 1809,
+ "overlap": 18,
+ "odds_ratio": 0.5428033022254127,
+ "p_value": 0.996141151799143,
+ "dataset": "scifate"
+ },
+ {
+ "rbp": "TRA2B",
+ "type": "cell-specific",
+ "n_predicted": 68,
+ "n_eclip": 626,
+ "overlap": 3,
+ "odds_ratio": 0.5392517594764786,
+ "p_value": 0.9112928210897431,
+ "dataset": "scifate"
+ }
+ ],
+ "aggregate_or": 0.5618568423446473,
+ "aggregate_p": 0.9999035180936869,
+ "aggregate_enrichment": 0.7427400667087654
+ }
+]
\ No newline at end of file
diff --git a/output/wrapup/figures/dentate_gyrus_sparsity.png b/output/wrapup/figures/dentate_gyrus_sparsity.png
new file mode 100644
index 0000000000000000000000000000000000000000..39a3322d71b5819fac420a5e6c482396775310b4
Binary files /dev/null and b/output/wrapup/figures/dentate_gyrus_sparsity.png differ
diff --git a/output/wrapup/results/wrapup_results.json b/output/wrapup/results/wrapup_results.json
new file mode 100644
index 0000000000000000000000000000000000000000..b1e60c7a83068170d27da35ffb4d5676bf034953
--- /dev/null
+++ b/output/wrapup/results/wrapup_results.json
@@ -0,0 +1,374 @@
+{
+ "pancreas": {
+ "fair_comparison": {
+ "mouse": {
+ "analytical_all": {
+ "r": -0.34966929477006137,
+ "n": 4611
+ },
+ "analytical_300": {
+ "r": -0.2040166725324759,
+ "n": 236
+ },
+ "deepptr_300": {
+ "r": -0.19762101977653473,
+ "n": 251
+ }
+ },
+ "human": {
+ "analytical_all": {
+ "r": -0.4020872107350974,
+ "n": 4308
+ },
+ "analytical_300": {
+ "r": -0.22231279755152644,
+ "n": 219
+ },
+ "deepptr_300": {
+ "r": -0.2767452667406712,
+ "n": 236
+ }
+ }
+ },
+ "bootstrap_ci": {
+ "spearman_r": -0.4020872107350974,
+ "n_genes": 4308,
+ "ci_95_lo": -0.4280150967698755,
+ "ci_95_hi": -0.37466333840185473,
+ "bootstrap_se": 0.013453487692476795
+ },
+ "eclip_validation": {
+ "n_pt_genes": 44,
+ "n_in_eclip": 23,
+ "frac_in_eclip": 0.5227272727272727,
+ "validated_genes": [
+ "ADGRB3",
+ "CHCHD3",
+ "DIP2C",
+ "DNAJC1",
+ "EGLN2",
+ "FARP1",
+ "FBXL17",
+ "FHIT",
+ "IGF2BP2",
+ "KCNQ1",
+ "MBD5",
+ "NR6A1",
+ "PAN3",
+ "PHLDB2",
+ "PTPRN2",
+ "RORA",
+ "SDK1",
+ "SND1",
+ "TCF12",
+ "TMCC1",
+ "TTLL3",
+ "WWOX",
+ "ZMYND8"
+ ],
+ "rbp_hits": {
+ "MATR3": [
+ "ADGRB3",
+ "CHCHD3",
+ "FARP1",
+ "FBXL17",
+ "FHIT",
+ "IGF2BP2",
+ "KCNQ1",
+ "MBD5",
+ "NR6A1",
+ "PAN3",
+ "PHLDB2",
+ "PTPRN2",
+ "SDK1",
+ "SND1",
+ "TCF12",
+ "WWOX",
+ "ZMYND8"
+ ],
+ "ELAVL1": [
+ "ADGRB3",
+ "CHCHD3",
+ "DNAJC1",
+ "FARP1",
+ "FHIT",
+ "IGF2BP2",
+ "MBD5",
+ "NR6A1",
+ "PAN3",
+ "SDK1",
+ "SND1",
+ "TCF12",
+ "TMCC1",
+ "ZMYND8"
+ ],
+ "RBFOX2": [
+ "DIP2C",
+ "FARP1",
+ "FHIT",
+ "IGF2BP2",
+ "KCNQ1",
+ "NR6A1",
+ "PTPRN2",
+ "SND1",
+ "TCF12",
+ "TTLL3",
+ "WWOX",
+ "ZMYND8"
+ ],
+ "FUS": [
+ "DIP2C",
+ "EGLN2",
+ "FARP1",
+ "KCNQ1",
+ "PTPRN2",
+ "RORA",
+ "SND1",
+ "TTLL3",
+ "ZMYND8"
+ ],
+ "HNRNPC": [
+ "FARP1",
+ "IGF2BP2",
+ "MBD5",
+ "PAN3",
+ "PTPRN2",
+ "SND1",
+ "TCF12",
+ "WWOX",
+ "ZMYND8"
+ ],
+ "HNRNPU": [
+ "FARP1",
+ "KCNQ1",
+ "SND1",
+ "ZMYND8"
+ ],
+ "MBNL2": [
+ "KCNQ1",
+ "MBD5",
+ "TCF12",
+ "ZMYND8"
+ ],
+ "TRA2B": [
+ "KCNQ1",
+ "TTLL3",
+ "ZMYND8"
+ ],
+ "HNRNPA1": [
+ "KCNQ1"
+ ]
+ }
+ },
+ "sparsity": {
+ "stratified": [
+ {
+ "quartile": "Q1 (lowest)",
+ "n_genes": 1081,
+ "spearman_r": -0.4687958859652454,
+ "median_detection": 0.036255411255411256
+ },
+ {
+ "quartile": "Q2",
+ "n_genes": 1075,
+ "spearman_r": -0.41976278876881845,
+ "median_detection": 0.06818181818181818
+ },
+ {
+ "quartile": "Q3",
+ "n_genes": 1079,
+ "spearman_r": -0.33749931613006473,
+ "median_detection": 0.12094155844155845
+ },
+ {
+ "quartile": "Q4 (highest)",
+ "n_genes": 1073,
+ "spearman_r": -0.29304334559984213,
+ "median_detection": 0.25405844155844154
+ }
+ ],
+ "detection_gamma_r": 0.6402610613282099
+ }
+ },
+ "dentate_gyrus": {
+ "fair_comparison": {
+ "mouse": {
+ "analytical_all": {
+ "r": -0.3179587682344816,
+ "n": 1217
+ },
+ "analytical_300": {
+ "r": -0.28646904360419734,
+ "n": 203
+ },
+ "deepptr_300": {
+ "r": -0.2852053996865196,
+ "n": 216
+ }
+ },
+ "human": {
+ "analytical_all": {
+ "r": -0.3812073018847205,
+ "n": 1126
+ },
+ "analytical_300": {
+ "r": -0.3593371092867718,
+ "n": 199
+ },
+ "deepptr_300": {
+ "r": -0.35768791768630437,
+ "n": 211
+ }
+ }
+ },
+ "bootstrap_ci": {
+ "spearman_r": -0.3812073018847205,
+ "n_genes": 1126,
+ "ci_95_lo": -0.4284031810417766,
+ "ci_95_hi": -0.32728699508514547,
+ "bootstrap_se": 0.025807048814683008
+ },
+ "eclip_validation": {
+ "n_pt_genes": 11,
+ "n_in_eclip": 5,
+ "frac_in_eclip": 0.45454545454545453,
+ "validated_genes": [
+ "CDH8",
+ "CNOT6",
+ "EML6",
+ "SCFD1",
+ "TAF13"
+ ],
+ "rbp_hits": {
+ "MATR3": [
+ "CNOT6",
+ "EML6",
+ "SCFD1"
+ ],
+ "ELAVL1": [
+ "CNOT6",
+ "SCFD1"
+ ],
+ "HNRNPC": [
+ "CNOT6",
+ "SCFD1"
+ ],
+ "HNRNPA1": [
+ "CDH8"
+ ],
+ "RBFOX2": [
+ "EML6"
+ ],
+ "TRA2B": [
+ "TAF13"
+ ]
+ }
+ },
+ "sparsity": {
+ "stratified": [
+ {
+ "quartile": "Q1 (lowest)",
+ "n_genes": 284,
+ "spearman_r": -0.43071286525006675,
+ "median_detection": 0.03447098976109215
+ },
+ {
+ "quartile": "Q2",
+ "n_genes": 282,
+ "spearman_r": -0.337181680598891,
+ "median_detection": 0.05
+ },
+ {
+ "quartile": "Q3",
+ "n_genes": 279,
+ "spearman_r": -0.30982074466292286,
+ "median_detection": 0.08156996587030717
+ },
+ {
+ "quartile": "Q4 (highest)",
+ "n_genes": 281,
+ "spearman_r": -0.389195011247454,
+ "median_detection": 0.18976109215017065
+ }
+ ],
+ "detection_gamma_r": 0.6376675725286252
+ }
+ },
+ "scifate_tautology": {
+ "r_gamma_gt": 0.992817592890788,
+ "r_gamma_over_beta_gt": 0.9984800928036497,
+ "r_raw_ratio_gt": 0.9649445360200416,
+ "beta_cv": 1.3545215701232527,
+ "r_beta_gamma": 0.9904040575638213,
+ "n_genes": 7927,
+ "tautology_severity": "high"
+ },
+ "ci_breakdown": {
+ "overall_coverage": 0.2694533333333333,
+ "target_coverage": 0.95,
+ "per_gene_cov_vs_std_r": 0.13542438638061674,
+ "per_gene_cov_vs_mean_r": 0.005736694141256186,
+ "median_relative_error": 0.35963016748428345,
+ "median_ci_width": 0.2299359142780304,
+ "median_true_range": 3.041830062866211,
+ "diagnosis": "overconfident"
+ },
+ "pt_enrichment": {
+ "pancreas": {
+ "n_pt_genes": 44,
+ "are_overlap": [],
+ "nmd_overlap": []
+ },
+ "dentate_gyrus": {
+ "n_pt_genes": 11,
+ "are_overlap": [],
+ "nmd_overlap": []
+ }
+ },
+ "limitations": [
+ {
+ "name": "Steady-state assumption",
+ "description": "Violated in actively differentiating cells; dynamic mode requires velocity (circular)"
+ },
+ {
+ "name": "Smoothing pre-processing",
+ "description": "Neighbor averaging collapses per-cell variation before gamma estimation"
+ },
+ {
+ "name": "Beta estimation",
+ "description": "Upper-quantile regression is crude; beta errors propagate directly into gamma"
+ },
+ {
+ "name": "Half-life correlations",
+ "description": "r=-0.35 to -0.40 explains ~15% of variance; modest biological signal"
+ },
+ {
+ "name": "sci-fate tautology",
+ "description": "gamma \u221d new/old \u2248 ground truth; high correlation is partially structural"
+ },
+ {
+ "name": "DeepPTR CI coverage",
+ "description": "27% for 95% CI; posterior is severely overconfident (amortized VI gap)"
+ },
+ {
+ "name": "Gene subset",
+ "description": "DeepPTR evaluated on 300 genes for CPU tractability; not full genome"
+ },
+ {
+ "name": "No method comparison",
+ "description": "No benchmarking against velVI, DeepVelo, scVI, or other deep methods"
+ },
+ {
+ "name": "Single seed",
+ "description": "No error bars; results may vary across random initializations"
+ },
+ {
+ "name": "PT-specific genes",
+ "description": "No external perturbation validation; could be technical artifacts"
+ },
+ {
+ "name": "Scalability",
+ "description": "Tested on 3K-7K cells; untested on modern 100K+ cell atlases"
+ }
+ ]
+}
\ No newline at end of file
diff --git a/tests/conftest.py b/tests/conftest.py
new file mode 100644
index 0000000000000000000000000000000000000000..d198e5de75552d03db8ece45130fb589935c647b
--- /dev/null
+++ b/tests/conftest.py
@@ -0,0 +1,69 @@
+"""Shared test fixtures for scPTR tests."""
+
+import numpy as np
+import pytest
+from anndata import AnnData
+from scipy.sparse import csr_matrix
+
+
+@pytest.fixture
+def synthetic_adata():
+ """Create a synthetic AnnData with unspliced/spliced layers (500 cells, 200 genes)."""
+ np.random.seed(42)
+ n_obs, n_vars = 500, 200
+
+ # Simulate spliced counts (Poisson-like)
+ spliced = np.random.exponential(5, size=(n_obs, n_vars)).astype(np.float32)
+ # Simulate unspliced as fraction of spliced with noise
+ unspliced = (spliced * np.random.uniform(0.05, 0.5, size=(1, n_vars))
+ + np.random.exponential(0.5, size=(n_obs, n_vars))).astype(np.float32)
+
+ adata = AnnData(
+ X=csr_matrix(spliced),
+ layers={
+ "spliced": csr_matrix(spliced),
+ "unspliced": csr_matrix(unspliced),
+ },
+ )
+ adata.obs_names = [f"cell_{i}" for i in range(n_obs)]
+ adata.var_names = [f"gene_{i}" for i in range(n_vars)]
+ return adata
+
+
+@pytest.fixture
+def preprocessed_adata(synthetic_adata):
+ """Synthetic AnnData that has been through the preprocessing pipeline."""
+ import scptr
+
+ scptr.pp.filter_genes(synthetic_adata, min_unspliced_counts=1, min_unspliced_cells=1)
+ scptr.pp.normalize_layers(synthetic_adata)
+ scptr.pp.neighbors(synthetic_adata, n_neighbors=30)
+ scptr.pp.smooth_layers(synthetic_adata)
+ return synthetic_adata
+
+
+@pytest.fixture
+def analyzed_adata(preprocessed_adata):
+ """Preprocessed AnnData that has been through core analysis."""
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+ scptr.tl.estimate_gamma(preprocessed_adata)
+ scptr.tl.variance_decomposition(preprocessed_adata)
+ scptr.tl.pt_states(preprocessed_adata)
+ return preprocessed_adata
+
+
+@pytest.fixture
+def velocity_adata(preprocessed_adata):
+ """Preprocessed AnnData with a synthetic velocity layer for dynamic gamma testing."""
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+
+ n_obs, n_vars = preprocessed_adata.shape
+ np.random.seed(99)
+ preprocessed_adata.layers["velocity_S"] = np.random.randn(n_obs, n_vars).astype(
+ np.float32
+ )
+ return preprocessed_adata
diff --git a/tests/test_benchmark.py b/tests/test_benchmark.py
new file mode 100644
index 0000000000000000000000000000000000000000..ad581a17f0dc7ee70ed40f71d73352c43b6ea068
--- /dev/null
+++ b/tests/test_benchmark.py
@@ -0,0 +1,122 @@
+"""Tests for the benchmark module."""
+
+import numpy as np
+import pandas as pd
+import pytest
+
+
+def test_correlate_with_halflives(analyzed_adata):
+ """correlate_with_halflives returns correlation dict."""
+ from scptr.benchmark import correlate_with_halflives
+
+ # Create synthetic half-life data matching some gene names
+ gene_names = analyzed_adata.var_names.tolist()
+ hl_df = pd.DataFrame({
+ "gene_symbol": gene_names[:50],
+ "half_life_hours": np.random.exponential(5, size=50),
+ })
+
+ result = correlate_with_halflives(analyzed_adata, hl_df)
+
+ assert "spearman_r" in result
+ assert "pearson_r" in result
+ assert "n_genes" in result
+ assert result["n_genes"] == 50
+
+
+def test_correlate_no_overlap(analyzed_adata):
+ """correlate_with_halflives handles no gene overlap gracefully."""
+ from scptr.benchmark import correlate_with_halflives
+
+ hl_df = pd.DataFrame({
+ "gene_symbol": ["FAKE_GENE_1", "FAKE_GENE_2"],
+ "half_life_hours": [5.0, 10.0],
+ })
+
+ result = correlate_with_halflives(analyzed_adata, hl_df)
+ assert result["n_genes"] == 0
+ assert np.isnan(result["spearman_r"])
+
+
+def test_are_enrichment(analyzed_adata):
+ """are_enrichment runs without error."""
+ from scptr.benchmark import are_enrichment
+
+ result = are_enrichment(analyzed_adata)
+ assert "label" in result
+ assert result["label"] == "ARE"
+ assert "p_value" in result
+
+
+def test_nmd_enrichment(analyzed_adata):
+ """nmd_enrichment runs without error."""
+ from scptr.benchmark import nmd_enrichment
+
+ result = nmd_enrichment(analyzed_adata)
+ assert "label" in result
+ assert result["label"] == "NMD"
+ assert "p_value" in result
+
+
+def test_subsampling_robustness(analyzed_adata):
+ """subsampling_robustness returns DataFrame with expected columns."""
+ from scptr.benchmark import subsampling_robustness
+
+ result = subsampling_robustness(
+ analyzed_adata, fractions=[0.5, 0.8], n_repeats=2
+ )
+
+ assert isinstance(result, pd.DataFrame)
+ assert "fraction" in result.columns
+ assert "spearman_r" in result.columns
+ assert "pearson_r" in result.columns
+ assert len(result) == 4 # 2 fractions * 2 repeats
+
+
+def test_cross_dataset_consistency(analyzed_adata):
+ """cross_dataset_consistency works with multiple copies."""
+ from scptr.benchmark import cross_dataset_consistency
+
+ result = cross_dataset_consistency({
+ "dataset_A": analyzed_adata,
+ "dataset_B": analyzed_adata,
+ })
+
+ assert isinstance(result, pd.DataFrame)
+ assert len(result) == 1 # 1 pair
+ assert "spearman_r" in result.columns
+ # Same data should have perfect correlation
+ assert result["spearman_r"].iloc[0] > 0.99
+
+
+def test_enrichment_barplot(analyzed_adata):
+ """enrichment_barplot produces a figure."""
+ import matplotlib
+ matplotlib.use("Agg")
+ from scptr.plotting import enrichment_barplot
+
+ results = [
+ {"label": "ARE", "median_gamma_in_set": 0.5,
+ "median_gamma_background": 0.3, "p_value": 0.01},
+ {"label": "NMD", "median_gamma_in_set": 0.6,
+ "median_gamma_background": 0.3, "p_value": 0.005},
+ ]
+
+ fig = enrichment_barplot(results)
+ assert fig is not None
+
+
+def test_halflife_scatter(analyzed_adata):
+ """halflife_scatter produces a figure."""
+ import matplotlib
+ matplotlib.use("Agg")
+ from scptr.plotting import halflife_scatter
+
+ gene_names = analyzed_adata.var_names.tolist()
+ hl_df = pd.DataFrame({
+ "gene_symbol": gene_names[:20],
+ "half_life_hours": np.random.exponential(5, size=20),
+ })
+
+ fig = halflife_scatter(analyzed_adata, hl_df)
+ assert fig is not None
diff --git a/tests/test_beta.py b/tests/test_beta.py
new file mode 100644
index 0000000000000000000000000000000000000000..fa8d51e22f3cf241696d3e1833a3d0a3899140c3
--- /dev/null
+++ b/tests/test_beta.py
@@ -0,0 +1,29 @@
+"""Tests for beta estimation."""
+
+import numpy as np
+import pytest
+
+
+def test_estimate_beta(preprocessed_adata):
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+ assert "beta" in preprocessed_adata.var.columns
+ beta = preprocessed_adata.var["beta"].values
+ assert beta.dtype == np.float32
+ assert len(beta) == preprocessed_adata.n_vars
+ assert np.all(beta >= 0)
+ assert "estimate_beta" in preprocessed_adata.uns["scptr"]
+
+
+def test_estimate_beta_quantile(preprocessed_adata):
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata, quantile=0.90)
+ beta_90 = preprocessed_adata.var["beta"].values.copy()
+
+ scptr.tl.estimate_beta(preprocessed_adata, quantile=0.99)
+ beta_99 = preprocessed_adata.var["beta"].values.copy()
+
+ # Higher quantile should give higher or equal beta
+ assert np.all(beta_99 >= beta_90 - 1e-6)
diff --git a/tests/test_beta_groupby.py b/tests/test_beta_groupby.py
new file mode 100644
index 0000000000000000000000000000000000000000..13d87a76bac8ecc22527187b4e0b08e65dc64d7b
--- /dev/null
+++ b/tests/test_beta_groupby.py
@@ -0,0 +1,68 @@
+"""Tests for per-cell-type beta estimation (groupby parameter)."""
+
+import numpy as np
+import pytest
+
+
+def test_groupby_produces_varm(preprocessed_adata):
+ """groupby stores per-group betas in adata.varm['beta_groups']."""
+ import scptr
+
+ preprocessed_adata.obs["cell_type"] = np.random.choice(
+ ["A", "B", "C"], size=preprocessed_adata.n_obs
+ )
+ scptr.tl.estimate_beta(preprocessed_adata, groupby="cell_type")
+
+ assert "beta_groups" in preprocessed_adata.varm
+ assert preprocessed_adata.varm["beta_groups"].shape == (
+ preprocessed_adata.n_vars,
+ 3,
+ )
+ assert "beta" in preprocessed_adata.var.columns
+
+
+def test_groupby_single_group_matches_global(preprocessed_adata):
+ """When there is only one group, groupby result matches global."""
+ import scptr
+
+ # Global estimation
+ scptr.tl.estimate_beta(preprocessed_adata)
+ beta_global = preprocessed_adata.var["beta"].values.copy()
+
+ # Single-group estimation
+ preprocessed_adata.obs["one_group"] = "all"
+ scptr.tl.estimate_beta(preprocessed_adata, groupby="one_group")
+ beta_grouped = preprocessed_adata.var["beta"].values.copy()
+
+ np.testing.assert_allclose(beta_global, beta_grouped, rtol=1e-5)
+
+
+def test_groupby_missing_column_raises(preprocessed_adata):
+ """groupby with nonexistent column raises KeyError."""
+ import scptr
+
+ with pytest.raises(KeyError, match="Missing required obs columns"):
+ scptr.tl.estimate_beta(preprocessed_adata, groupby="nonexistent")
+
+
+def test_groupby_consensus_is_clipped_median(preprocessed_adata):
+ """Consensus beta is median across group betas, then globally clipped."""
+ import scptr
+
+ preprocessed_adata.obs["cell_type"] = np.random.choice(
+ ["X", "Y"], size=preprocessed_adata.n_obs
+ )
+ scptr.tl.estimate_beta(preprocessed_adata, groupby="cell_type")
+
+ beta_groups = preprocessed_adata.varm["beta_groups"]
+ raw_median = np.nanmedian(beta_groups.values, axis=1)
+ # Apply the same global clip as the implementation
+ positive = raw_median[raw_median > 0]
+ if len(positive) > 0:
+ cap = np.percentile(positive, 99)
+ expected = np.clip(raw_median, 0, cap).astype(np.float32)
+ else:
+ expected = raw_median.astype(np.float32)
+ actual = preprocessed_adata.var["beta"].values
+
+ np.testing.assert_allclose(actual, expected, rtol=1e-5)
diff --git a/tests/test_datasets.py b/tests/test_datasets.py
new file mode 100644
index 0000000000000000000000000000000000000000..084051fa65bcafc7850fbcaaa9124836b495fa6b
--- /dev/null
+++ b/tests/test_datasets.py
@@ -0,0 +1,50 @@
+"""Tests for the datasets module."""
+
+import pytest
+import pandas as pd
+
+
+def test_herzog2017_halflives():
+ """Bundled Herzog 2017 half-lives load correctly."""
+ from scptr.datasets import herzog2017_halflives
+
+ df = herzog2017_halflives()
+ assert isinstance(df, pd.DataFrame)
+ assert "gene_symbol" in df.columns
+ assert "half_life_hours" in df.columns
+ assert len(df) > 50
+ assert df["half_life_hours"].min() > 0
+
+
+def test_schofield2018_halflives():
+ """Bundled Schofield 2018 half-lives load correctly."""
+ from scptr.datasets import schofield2018_halflives
+
+ df = schofield2018_halflives()
+ assert isinstance(df, pd.DataFrame)
+ assert "gene_symbol" in df.columns
+ assert "half_life_hours" in df.columns
+ assert len(df) > 50
+ assert df["half_life_hours"].min() > 0
+
+
+@pytest.mark.slow
+def test_pancreas_download():
+ """Pancreas dataset downloads and loads."""
+ from scptr.datasets import pancreas
+
+ adata = pancreas()
+ assert adata.n_obs > 0
+ assert adata.n_vars > 0
+
+
+@pytest.mark.slow
+def test_dentate_gyrus_download():
+ """Dentate gyrus dataset downloads and loads."""
+ from scptr.datasets import dentate_gyrus
+
+ adata = dentate_gyrus()
+ assert adata.n_obs > 0
+ assert adata.n_vars > 0
+
+
diff --git a/tests/test_deep_data.py b/tests/test_deep_data.py
new file mode 100644
index 0000000000000000000000000000000000000000..45d749fe90dc1365d6e0761a32e4fb01e75d992c
--- /dev/null
+++ b/tests/test_deep_data.py
@@ -0,0 +1,93 @@
+"""Tests for DeepPTR data loading utilities."""
+
+import numpy as np
+import pytest
+import torch
+from anndata import AnnData
+
+from scptr.deep._data import setup_dataloaders
+from scptr.deep._utils import get_library_sizes
+
+
+@pytest.fixture
+def simple_adata():
+ """AnnData with spliced/unspliced counts."""
+ rng = np.random.RandomState(42)
+ n, g = 100, 20
+ s = rng.poisson(5, size=(n, g)).astype(np.float32)
+ u = rng.poisson(2, size=(n, g)).astype(np.float32)
+ adata = AnnData(X=s)
+ adata.layers["spliced"] = s
+ adata.layers["unspliced"] = u
+ adata.obs["cell_type"] = [f"type_{i % 3}" for i in range(n)]
+ adata.obs["cell_type"] = adata.obs["cell_type"].astype("category")
+ return adata
+
+
+class TestGetLibrarySizes:
+ def test_shapes(self, simple_adata):
+ l_u, l_s = get_library_sizes(simple_adata)
+ assert l_u.shape == (simple_adata.n_obs,)
+ assert l_s.shape == (simple_adata.n_obs,)
+
+ def test_positive(self, simple_adata):
+ l_u, l_s = get_library_sizes(simple_adata)
+ assert (l_u >= 1.0).all()
+ assert (l_s >= 1.0).all()
+
+ def test_correct_sums(self, simple_adata):
+ l_u, l_s = get_library_sizes(simple_adata)
+ expected_s = simple_adata.layers["spliced"].sum(axis=1)
+ expected_u = simple_adata.layers["unspliced"].sum(axis=1)
+ np.testing.assert_allclose(l_s, np.clip(expected_s, 1.0, None), rtol=1e-5)
+ np.testing.assert_allclose(l_u, np.clip(expected_u, 1.0, None), rtol=1e-5)
+
+ def test_missing_layer_raises(self):
+ adata = AnnData(X=np.zeros((5, 3)))
+ with pytest.raises(KeyError, match="Missing required layer"):
+ get_library_sizes(adata)
+
+
+class TestSetupDataloaders:
+ def test_returns_four(self, simple_adata):
+ train_dl, val_dl, train_idx, val_idx = setup_dataloaders(
+ simple_adata, batch_size=16, val_frac=0.2, seed=0
+ )
+ assert isinstance(train_dl, torch.utils.data.DataLoader)
+ assert isinstance(val_dl, torch.utils.data.DataLoader)
+ assert len(train_idx) + len(val_idx) == simple_adata.n_obs
+
+ def test_no_overlap(self, simple_adata):
+ _, _, train_idx, val_idx = setup_dataloaders(
+ simple_adata, batch_size=16, val_frac=0.2, seed=0
+ )
+ assert len(set(train_idx) & set(val_idx)) == 0
+
+ def test_batch_contents(self, simple_adata):
+ train_dl, _, _, _ = setup_dataloaders(
+ simple_adata, batch_size=16, val_frac=0.1, seed=0
+ )
+ s, u, l_s, l_u = next(iter(train_dl))
+ assert s.ndim == 2
+ assert u.ndim == 2
+ assert l_s.ndim == 1
+ assert l_u.ndim == 1
+ assert s.shape[1] == simple_adata.n_vars
+
+ def test_stratified_split(self, simple_adata):
+ _, _, train_idx, val_idx = setup_dataloaders(
+ simple_adata,
+ batch_size=16,
+ val_frac=0.2,
+ stratify_key="cell_type",
+ seed=0,
+ )
+ # All cell types should appear in both splits
+ train_types = set(simple_adata.obs["cell_type"].values[train_idx])
+ val_types = set(simple_adata.obs["cell_type"].values[val_idx])
+ assert train_types == val_types
+
+ def test_reproducible(self, simple_adata):
+ _, _, idx1, _ = setup_dataloaders(simple_adata, seed=42)
+ _, _, idx2, _ = setup_dataloaders(simple_adata, seed=42)
+ np.testing.assert_array_equal(idx1, idx2)
diff --git a/tests/test_deep_distributions.py b/tests/test_deep_distributions.py
new file mode 100644
index 0000000000000000000000000000000000000000..b4b32511b23f399e16af807148343844ba8d09c8
--- /dev/null
+++ b/tests/test_deep_distributions.py
@@ -0,0 +1,73 @@
+"""Tests for NB distribution utilities."""
+
+import numpy as np
+import pytest
+import torch
+
+from scptr.deep._distributions import log_nb_positive
+
+
+class TestLogNBPositive:
+ def test_output_shape(self):
+ x = torch.tensor([[1.0, 2.0, 3.0]])
+ mu = torch.tensor([[2.0, 2.0, 2.0]])
+ theta = torch.tensor([5.0, 5.0, 5.0])
+ ll = log_nb_positive(x, mu, theta)
+ assert ll.shape == (1, 3)
+
+ def test_non_positive(self):
+ """Log-probabilities should be <= 0."""
+ x = torch.randint(0, 20, (100, 50)).float()
+ mu = torch.rand(100, 50) * 10 + 0.1
+ theta = torch.rand(50) * 10 + 0.1
+ ll = log_nb_positive(x, mu, theta)
+ assert (ll <= 1e-5).all(), "Log probabilities should be non-positive"
+
+ def test_peak_at_mean(self):
+ """For integer means, likelihood should peak near the mean."""
+ mu = torch.tensor([[10.0]])
+ theta = torch.tensor([50.0]) # low dispersion
+ xs = torch.arange(0, 30).float().unsqueeze(1)
+ ll = log_nb_positive(xs, mu.expand(30, 1), theta)
+ peak = ll.argmax().item()
+ assert abs(peak - 10) <= 2, f"Peak at {peak}, expected near 10"
+
+ def test_higher_theta_less_variance(self):
+ """Higher theta (less dispersion) should give sharper distribution."""
+ mu = torch.tensor([[5.0]])
+ xs = torch.arange(0, 20).float().unsqueeze(1)
+
+ theta_low = torch.tensor([1.0])
+ theta_high = torch.tensor([100.0])
+
+ ll_low = log_nb_positive(xs, mu.expand(20, 1), theta_low)
+ ll_high = log_nb_positive(xs, mu.expand(20, 1), theta_high)
+
+ # High theta should have higher peak probability
+ assert ll_high.max() > ll_low.max()
+
+ def test_gradient_flows(self):
+ """Ensure gradients flow through all parameters."""
+ x = torch.tensor([[3.0, 5.0]])
+ mu = torch.tensor([[2.0, 4.0]], requires_grad=True)
+ theta = torch.tensor([5.0, 5.0], requires_grad=True)
+ ll = log_nb_positive(x, mu, theta).sum()
+ ll.backward()
+ assert mu.grad is not None
+ assert theta.grad is not None
+ assert not torch.isnan(mu.grad).any()
+ assert not torch.isnan(theta.grad).any()
+
+ def test_batch_consistency(self):
+ """Batched computation should match individual computation."""
+ torch.manual_seed(42)
+ x = torch.randint(0, 10, (5, 3)).float()
+ mu = torch.rand(5, 3) * 5 + 0.1
+ theta = torch.rand(3) * 5 + 0.1
+
+ ll_batch = log_nb_positive(x, mu, theta)
+ for i in range(5):
+ ll_single = log_nb_positive(
+ x[i : i + 1], mu[i : i + 1], theta
+ )
+ assert torch.allclose(ll_batch[i], ll_single[0], atol=1e-5)
diff --git a/tests/test_deep_guide.py b/tests/test_deep_guide.py
new file mode 100644
index 0000000000000000000000000000000000000000..bdd5a6558b6ae9efd48a7b3a2af47c93c8a4505a
--- /dev/null
+++ b/tests/test_deep_guide.py
@@ -0,0 +1,93 @@
+"""Tests for DeepPTR posterior extraction."""
+
+import numpy as np
+import pytest
+import torch
+
+from scptr.deep._model import DeepPTR
+from scptr.deep._guide import posterior_gamma, extract_latent
+
+
+@pytest.fixture
+def trained_model_and_adata():
+ """A small model with matching AnnData (untrained, just for shape checks)."""
+ from anndata import AnnData
+
+ rng = np.random.RandomState(0)
+ n, g = 50, 20
+ s = rng.poisson(5, size=(n, g)).astype(np.float32)
+ u = rng.poisson(2, size=(n, g)).astype(np.float32)
+ adata = AnnData(X=s)
+ adata.layers["spliced"] = s
+ adata.layers["unspliced"] = u
+
+ torch.manual_seed(0)
+ model = DeepPTR(n_genes=g, d_T=3, d_PT=3, d_hidden=16, n_enc_layers=1)
+ model.eval()
+ return model, adata
+
+
+class TestPosteriorGamma:
+ def test_shapes(self, trained_model_and_adata):
+ model, adata = trained_model_and_adata
+ gamma_mean, gamma_var = posterior_gamma(
+ model, adata, n_samples=5, batch_size=16, device="cpu"
+ )
+ assert gamma_mean.shape == (adata.n_obs, adata.n_vars)
+ assert gamma_var.shape == (adata.n_obs, adata.n_vars)
+
+ def test_positive_values(self, trained_model_and_adata):
+ model, adata = trained_model_and_adata
+ gamma_mean, gamma_var = posterior_gamma(
+ model, adata, n_samples=5, device="cpu"
+ )
+ assert (gamma_mean >= 0).all()
+ assert (gamma_var >= 0).all()
+
+ def test_no_nans(self, trained_model_and_adata):
+ model, adata = trained_model_and_adata
+ gamma_mean, gamma_var = posterior_gamma(
+ model, adata, n_samples=5, device="cpu"
+ )
+ assert not np.isnan(gamma_mean).any()
+ assert not np.isnan(gamma_var).any()
+
+ def test_more_samples_lower_variance_of_mean(self, trained_model_and_adata):
+ """With more MC samples, the posterior mean estimate should be more stable."""
+ model, adata = trained_model_and_adata
+ means = []
+ for _ in range(3):
+ gm, _ = posterior_gamma(model, adata, n_samples=2, device="cpu")
+ means.append(gm.mean())
+ spread_few = np.std(means)
+
+ means = []
+ for _ in range(3):
+ gm, _ = posterior_gamma(model, adata, n_samples=20, device="cpu")
+ means.append(gm.mean())
+ spread_many = np.std(means)
+
+ # Not a hard guarantee, but should generally hold
+ # Use a generous threshold — we just want a sanity check
+ assert spread_many < spread_few * 5
+
+
+class TestExtractLatent:
+ def test_shapes(self, trained_model_and_adata):
+ model, adata = trained_model_and_adata
+ z_T, z_PT = extract_latent(model, adata, batch_size=16, device="cpu")
+ assert z_T.shape == (adata.n_obs, model.d_T)
+ assert z_PT.shape == (adata.n_obs, model.d_PT)
+
+ def test_deterministic(self, trained_model_and_adata):
+ model, adata = trained_model_and_adata
+ z_T1, z_PT1 = extract_latent(model, adata, device="cpu")
+ z_T2, z_PT2 = extract_latent(model, adata, device="cpu")
+ np.testing.assert_allclose(z_T1, z_T2, atol=1e-6)
+ np.testing.assert_allclose(z_PT1, z_PT2, atol=1e-6)
+
+ def test_no_nans(self, trained_model_and_adata):
+ model, adata = trained_model_and_adata
+ z_T, z_PT = extract_latent(model, adata, device="cpu")
+ assert not np.isnan(z_T).any()
+ assert not np.isnan(z_PT).any()
diff --git a/tests/test_deep_model.py b/tests/test_deep_model.py
new file mode 100644
index 0000000000000000000000000000000000000000..5b37974e40be19892ab8acc441ac45e56449b4be
--- /dev/null
+++ b/tests/test_deep_model.py
@@ -0,0 +1,176 @@
+"""Tests for DeepPTR model components."""
+
+import numpy as np
+import pytest
+import torch
+
+from scptr.deep._model import DeepPTR, Encoder, KineticDecoder
+
+
+@pytest.fixture
+def model_dims():
+ return {"n_genes": 50, "d_T": 5, "d_PT": 5, "d_hidden": 32}
+
+
+@pytest.fixture
+def batch_data(model_dims):
+ """Synthetic batch of data."""
+ torch.manual_seed(0)
+ n = 16
+ G = model_dims["n_genes"]
+ return {
+ "s": torch.rand(n, G) * 10,
+ "u": torch.rand(n, G) * 5,
+ "l_s": torch.rand(n) * 1000 + 100,
+ "l_u": torch.rand(n) * 500 + 50,
+ }
+
+
+class TestEncoder:
+ def test_output_shapes(self, model_dims):
+ enc = Encoder(
+ n_genes=model_dims["n_genes"],
+ d_hidden=model_dims["d_hidden"],
+ d_T=model_dims["d_T"],
+ d_PT=model_dims["d_PT"],
+ )
+ s = torch.rand(8, model_dims["n_genes"])
+ u = torch.rand(8, model_dims["n_genes"])
+ mu_T, logvar_T, mu_PT, logvar_PT = enc(s, u)
+ assert mu_T.shape == (8, model_dims["d_T"])
+ assert logvar_T.shape == (8, model_dims["d_T"])
+ assert mu_PT.shape == (8, model_dims["d_PT"])
+ assert logvar_PT.shape == (8, model_dims["d_PT"])
+
+ def test_different_inputs_different_outputs(self, model_dims):
+ enc = Encoder(
+ n_genes=model_dims["n_genes"],
+ d_hidden=model_dims["d_hidden"],
+ d_T=model_dims["d_T"],
+ d_PT=model_dims["d_PT"],
+ )
+ s1 = torch.rand(1, model_dims["n_genes"])
+ u1 = torch.rand(1, model_dims["n_genes"])
+ s2 = torch.rand(1, model_dims["n_genes"]) + 5
+ u2 = torch.rand(1, model_dims["n_genes"]) + 5
+
+ out1 = enc(s1, u1)
+ out2 = enc(s2, u2)
+ assert not torch.allclose(out1[0], out2[0])
+
+
+class TestKineticDecoder:
+ def test_output_shapes(self, model_dims):
+ dec = KineticDecoder(
+ n_genes=model_dims["n_genes"],
+ d_T=model_dims["d_T"],
+ d_PT=model_dims["d_PT"],
+ d_hidden=model_dims["d_hidden"],
+ )
+ z_T = torch.randn(8, model_dims["d_T"])
+ z_PT = torch.randn(8, model_dims["d_PT"])
+ l_s = torch.ones(8) * 1000
+ l_u = torch.ones(8) * 500
+ out = dec(z_T, z_PT, l_s, l_u)
+
+ G = model_dims["n_genes"]
+ assert out["mu_s"].shape == (8, G)
+ assert out["mu_u"].shape == (8, G)
+ assert out["alpha"].shape == (8, G)
+ assert out["gamma"].shape == (8, G)
+ assert out["beta"].shape == (G,)
+ assert out["theta_s"].shape == (G,)
+ assert out["theta_u"].shape == (G,)
+
+ def test_positive_outputs(self, model_dims):
+ dec = KineticDecoder(
+ n_genes=model_dims["n_genes"],
+ d_T=model_dims["d_T"],
+ d_PT=model_dims["d_PT"],
+ d_hidden=model_dims["d_hidden"],
+ )
+ z_T = torch.randn(16, model_dims["d_T"])
+ z_PT = torch.randn(16, model_dims["d_PT"])
+ l_s = torch.ones(16) * 1000
+ l_u = torch.ones(16) * 500
+ out = dec(z_T, z_PT, l_s, l_u)
+
+ for key in ("mu_s", "mu_u", "alpha", "gamma", "beta", "theta_s", "theta_u"):
+ assert (out[key] >= 0).all(), f"{key} has negative values"
+
+ def test_mu_scales_with_library_size(self, model_dims):
+ dec = KineticDecoder(
+ n_genes=model_dims["n_genes"],
+ d_T=model_dims["d_T"],
+ d_PT=model_dims["d_PT"],
+ d_hidden=model_dims["d_hidden"],
+ )
+ z_T = torch.randn(1, model_dims["d_T"])
+ z_PT = torch.randn(1, model_dims["d_PT"])
+
+ out1 = dec(z_T, z_PT, torch.tensor([100.0]), torch.tensor([100.0]))
+ out2 = dec(z_T, z_PT, torch.tensor([1000.0]), torch.tensor([1000.0]))
+
+ ratio_s = out2["mu_s"].sum() / out1["mu_s"].sum()
+ assert abs(ratio_s.item() - 10.0) < 1.0
+
+ def test_beta_is_not_cell_specific(self, model_dims):
+ """Beta should be the same regardless of input."""
+ dec = KineticDecoder(
+ n_genes=model_dims["n_genes"],
+ d_T=model_dims["d_T"],
+ d_PT=model_dims["d_PT"],
+ d_hidden=model_dims["d_hidden"],
+ )
+ z_T1 = torch.randn(4, model_dims["d_T"])
+ z_PT1 = torch.randn(4, model_dims["d_PT"])
+ z_T2 = torch.randn(4, model_dims["d_T"])
+ z_PT2 = torch.randn(4, model_dims["d_PT"])
+
+ out1 = dec(z_T1, z_PT1, torch.ones(4), torch.ones(4))
+ out2 = dec(z_T2, z_PT2, torch.ones(4), torch.ones(4))
+ assert torch.allclose(out1["beta"], out2["beta"])
+
+
+class TestDeepPTR:
+ def test_forward_loss(self, model_dims, batch_data):
+ model = DeepPTR(**model_dims)
+ out = model(**batch_data)
+ assert "loss" in out
+ assert "recon_loss" in out
+ assert "kl_loss" in out
+ assert not torch.isnan(out["loss"])
+
+ def test_backward(self, model_dims, batch_data):
+ model = DeepPTR(**model_dims)
+ out = model(**batch_data)
+ out["loss"].backward()
+ for name, p in model.named_parameters():
+ if p.requires_grad:
+ assert p.grad is not None, f"No gradient for {name}"
+ assert not torch.isnan(p.grad).any(), f"NaN gradient for {name}"
+
+ def test_kl_weight_zero(self, model_dims, batch_data):
+ model = DeepPTR(**model_dims)
+ out_0 = model(**batch_data, kl_weight=0.0)
+ out_1 = model(**batch_data, kl_weight=1.0)
+ # With kl_weight=0, loss should equal recon_loss
+ assert torch.allclose(out_0["loss"], out_0["recon_loss"], atol=1e-5)
+ # With kl_weight=1, loss > recon_loss (KL >= 0)
+ assert out_1["loss"] >= out_1["recon_loss"] - 1e-5
+
+ def test_get_latent(self, model_dims, batch_data):
+ model = DeepPTR(**model_dims)
+ mu_T, logvar_T, mu_PT, logvar_PT = model.get_latent(
+ batch_data["s"], batch_data["u"]
+ )
+ assert mu_T.shape == (16, model_dims["d_T"])
+ assert mu_PT.shape == (16, model_dims["d_PT"])
+
+ def test_reparameterize_stochastic(self, model_dims):
+ mu = torch.zeros(10, model_dims["d_T"])
+ logvar = torch.zeros(10, model_dims["d_T"])
+ z1 = DeepPTR.reparameterize(mu, logvar)
+ z2 = DeepPTR.reparameterize(mu, logvar)
+ # Two samples should differ (with overwhelming probability)
+ assert not torch.allclose(z1, z2)
diff --git a/tests/test_deep_synthetic.py b/tests/test_deep_synthetic.py
new file mode 100644
index 0000000000000000000000000000000000000000..dd6030bcd284b8ce8e11d6a2c0c9481a8f26a26a
--- /dev/null
+++ b/tests/test_deep_synthetic.py
@@ -0,0 +1,112 @@
+"""Tests for DeepPTR synthetic data generation and metrics."""
+
+import numpy as np
+import pytest
+
+from scptr.deep.synthetic import generate_kinetic_data, gamma_recovery, ci_coverage, latent_recovery
+
+
+class TestGenerateKineticData:
+ def test_shapes(self):
+ adata, truth = generate_kinetic_data(n_cells=100, n_genes=30, seed=0)
+ assert adata.n_obs == 100
+ assert adata.n_vars == 30
+ assert adata.layers["spliced"].shape == (100, 30)
+ assert adata.layers["unspliced"].shape == (100, 30)
+
+ def test_truth_keys(self):
+ _, truth = generate_kinetic_data(n_cells=50, n_genes=20)
+ for key in ("alpha", "gamma", "beta", "z_T", "z_PT"):
+ assert key in truth
+
+ def test_truth_shapes(self):
+ adata, truth = generate_kinetic_data(n_cells=50, n_genes=20)
+ assert truth["alpha"].shape == (50, 20)
+ assert truth["gamma"].shape == (50, 20)
+ assert truth["beta"].shape == (20,)
+ assert truth["z_T"].shape[0] == 50
+ assert truth["z_PT"].shape[0] == 50
+
+ def test_non_negative_counts(self):
+ adata, _ = generate_kinetic_data(n_cells=200, n_genes=50)
+ assert (adata.layers["spliced"] >= 0).all()
+ assert (adata.layers["unspliced"] >= 0).all()
+
+ def test_cell_types(self):
+ adata, _ = generate_kinetic_data(n_cells=100, n_cell_types=4)
+ assert "cell_type" in adata.obs.columns
+ assert adata.obs["cell_type"].nunique() <= 4
+
+ def test_sparsity(self):
+ adata_sparse, _ = generate_kinetic_data(n_cells=500, n_genes=100, sparsity=0.5)
+ adata_dense, _ = generate_kinetic_data(n_cells=500, n_genes=100, sparsity=0.0)
+ frac_zero_sparse = (adata_sparse.layers["spliced"] == 0).mean()
+ frac_zero_dense = (adata_dense.layers["spliced"] == 0).mean()
+ assert frac_zero_sparse > frac_zero_dense
+
+ def test_reproducible(self):
+ adata1, t1 = generate_kinetic_data(seed=42)
+ adata2, t2 = generate_kinetic_data(seed=42)
+ np.testing.assert_array_equal(
+ adata1.layers["spliced"], adata2.layers["spliced"]
+ )
+ np.testing.assert_array_equal(t1["gamma"], t2["gamma"])
+
+
+class TestGammaRecovery:
+ def test_perfect_recovery(self):
+ rng = np.random.RandomState(0)
+ gamma = rng.rand(100, 20).astype(np.float32)
+ r = gamma_recovery(gamma, gamma, per_gene=True)
+ assert r > 0.99
+
+ def test_random_is_low(self):
+ rng = np.random.RandomState(0)
+ g1 = rng.rand(100, 20).astype(np.float32)
+ g2 = rng.rand(100, 20).astype(np.float32)
+ r = gamma_recovery(g1, g2, per_gene=True)
+ assert abs(r) < 0.3
+
+ def test_global_mode(self):
+ rng = np.random.RandomState(0)
+ gamma = rng.rand(100, 20).astype(np.float32)
+ r = gamma_recovery(gamma, gamma, per_gene=False)
+ assert r > 0.99
+
+
+class TestCICoverage:
+ def test_perfect_coverage(self):
+ rng = np.random.RandomState(0)
+ gamma = rng.rand(100, 20).astype(np.float32)
+ # Huge variance → everything covered
+ cov = ci_coverage(gamma, gamma, np.ones_like(gamma) * 100.0)
+ assert cov > 0.99
+
+ def test_zero_variance_coverage(self):
+ rng = np.random.RandomState(0)
+ gamma_true = rng.rand(100, 20).astype(np.float32)
+ gamma_pred = gamma_true + 1.0 # shifted
+ # Tiny variance → nothing covered
+ cov = ci_coverage(gamma_true, gamma_pred, np.ones_like(gamma_true) * 1e-10)
+ assert cov < 0.05
+
+ def test_returns_fraction(self):
+ rng = np.random.RandomState(0)
+ gamma = rng.rand(50, 10).astype(np.float32)
+ cov = ci_coverage(gamma, gamma, np.ones_like(gamma) * 0.1)
+ assert 0.0 <= cov <= 1.0
+
+
+class TestLatentRecovery:
+ def test_perfect_recovery(self):
+ rng = np.random.RandomState(0)
+ z = rng.randn(100, 5).astype(np.float32)
+ r = latent_recovery(z, z)
+ assert r > 0.99
+
+ def test_random_is_lower(self):
+ rng = np.random.RandomState(0)
+ z1 = rng.randn(100, 5).astype(np.float32)
+ z2 = rng.randn(100, 5).astype(np.float32)
+ r = latent_recovery(z1, z2)
+ assert r < 0.5
diff --git a/tests/test_deep_trainer.py b/tests/test_deep_trainer.py
new file mode 100644
index 0000000000000000000000000000000000000000..a75a590f7fb13ff748b54853c69248737884cd7a
--- /dev/null
+++ b/tests/test_deep_trainer.py
@@ -0,0 +1,103 @@
+"""Tests for DeepPTR training loop."""
+
+import numpy as np
+import pytest
+import torch
+
+from scptr.deep._model import DeepPTR
+from scptr.deep._trainer import Trainer, TrainHistory
+from scptr.deep._data import setup_dataloaders
+
+
+@pytest.fixture
+def tiny_adata():
+ """Minimal AnnData for training tests."""
+ from anndata import AnnData
+
+ rng = np.random.RandomState(0)
+ n, g = 80, 30
+ s = rng.poisson(5, size=(n, g)).astype(np.float32)
+ u = rng.poisson(2, size=(n, g)).astype(np.float32)
+ adata = AnnData(X=s)
+ adata.layers["spliced"] = s
+ adata.layers["unspliced"] = u
+ return adata
+
+
+@pytest.fixture
+def tiny_loaders(tiny_adata):
+ train_dl, val_dl, _, _ = setup_dataloaders(
+ tiny_adata, batch_size=32, val_frac=0.2, seed=0
+ )
+ return train_dl, val_dl
+
+
+class TestTrainer:
+ def test_fit_runs(self, tiny_loaders):
+ train_dl, val_dl = tiny_loaders
+ model = DeepPTR(n_genes=30, d_T=3, d_PT=3, d_hidden=16, n_enc_layers=1)
+ trainer = Trainer(
+ model=model,
+ max_epochs=5,
+ kl_warmup_epochs=2,
+ patience=100,
+ device="cpu",
+ )
+ history = trainer.fit(train_dl, val_dl, verbose=False)
+ assert isinstance(history, TrainHistory)
+ assert len(history.train_loss) == 5
+ assert len(history.val_loss) == 5
+
+ def test_loss_decreases(self, tiny_loaders):
+ train_dl, val_dl = tiny_loaders
+ model = DeepPTR(n_genes=30, d_T=3, d_PT=3, d_hidden=16, n_enc_layers=1)
+ trainer = Trainer(
+ model=model,
+ max_epochs=30,
+ kl_warmup_epochs=5,
+ patience=100,
+ device="cpu",
+ )
+ history = trainer.fit(train_dl, val_dl, verbose=False)
+ # Training loss should decrease from start to end
+ assert history.train_loss[-1] < history.train_loss[0]
+
+ def test_early_stopping(self, tiny_loaders):
+ train_dl, val_dl = tiny_loaders
+ model = DeepPTR(n_genes=30, d_T=3, d_PT=3, d_hidden=16, n_enc_layers=1)
+ trainer = Trainer(
+ model=model,
+ max_epochs=500,
+ kl_warmup_epochs=2,
+ patience=3,
+ device="cpu",
+ )
+ history = trainer.fit(train_dl, val_dl, verbose=False)
+ # Should stop before max_epochs
+ assert len(history.train_loss) < 500
+
+ def test_kl_warmup(self, tiny_loaders):
+ train_dl, val_dl = tiny_loaders
+ model = DeepPTR(n_genes=30, d_T=3, d_PT=3, d_hidden=16, n_enc_layers=1)
+ trainer = Trainer(
+ model=model,
+ max_epochs=10,
+ kl_warmup_epochs=5,
+ patience=100,
+ device="cpu",
+ )
+ history = trainer.fit(train_dl, val_dl, verbose=False)
+ # KL weight should ramp up
+ assert history.kl_weight[0] < history.kl_weight[-1]
+ assert history.kl_weight[0] < 1.0
+
+ def test_history_fields(self, tiny_loaders):
+ train_dl, val_dl = tiny_loaders
+ model = DeepPTR(n_genes=30, d_T=3, d_PT=3, d_hidden=16, n_enc_layers=1)
+ trainer = Trainer(
+ model=model, max_epochs=3, kl_warmup_epochs=1, patience=100, device="cpu"
+ )
+ history = trainer.fit(train_dl, val_dl, verbose=False)
+ for attr in ("train_loss", "val_loss", "train_recon", "val_recon",
+ "train_kl", "val_kl", "kl_weight", "lr"):
+ assert len(getattr(history, attr)) == 3
diff --git a/tests/test_gamma.py b/tests/test_gamma.py
new file mode 100644
index 0000000000000000000000000000000000000000..8a7b899a5b841f9a750a5df42a27bc943d916d07
--- /dev/null
+++ b/tests/test_gamma.py
@@ -0,0 +1,39 @@
+"""Tests for gamma estimation."""
+
+import numpy as np
+import pytest
+
+
+def test_estimate_gamma(preprocessed_adata):
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+ scptr.tl.estimate_gamma(preprocessed_adata)
+
+ assert "gamma" in preprocessed_adata.layers
+ gamma = preprocessed_adata.layers["gamma"]
+ assert gamma.shape == preprocessed_adata.shape
+ assert gamma.dtype == np.float32
+ assert np.all(gamma >= 0)
+ assert "estimate_gamma" in preprocessed_adata.uns["scptr"]
+
+
+def test_gamma_clipping(preprocessed_adata):
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+ scptr.tl.estimate_gamma(preprocessed_adata, clip_quantile=0.95)
+ gamma_95 = preprocessed_adata.layers["gamma"].copy()
+
+ scptr.tl.estimate_gamma(preprocessed_adata, clip_quantile=0.5)
+ gamma_50 = preprocessed_adata.layers["gamma"].copy()
+
+ # Stricter clipping should give lower or equal max values
+ assert gamma_50.max() <= gamma_95.max() + 1e-6
+
+
+def test_gamma_requires_beta(preprocessed_adata):
+ import scptr
+
+ with pytest.raises(KeyError):
+ scptr.tl.estimate_gamma(preprocessed_adata)
diff --git a/tests/test_gamma_dynamic.py b/tests/test_gamma_dynamic.py
new file mode 100644
index 0000000000000000000000000000000000000000..9991d5748b3de125ee8cf6967728a6556223b823
--- /dev/null
+++ b/tests/test_gamma_dynamic.py
@@ -0,0 +1,76 @@
+"""Tests for dynamic-mode gamma estimation."""
+
+import numpy as np
+import pytest
+
+
+def test_dynamic_mode_produces_gamma(preprocessed_adata):
+ """Dynamic mode produces a gamma layer."""
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+
+ # Create a synthetic velocity layer (ds/dt estimate)
+ n_obs, n_vars = preprocessed_adata.shape
+ preprocessed_adata.layers["velocity_S"] = np.random.randn(n_obs, n_vars).astype(
+ np.float32
+ )
+
+ scptr.tl.estimate_gamma(
+ preprocessed_adata, mode="dynamic", velocity_layer="velocity_S"
+ )
+
+ assert "gamma" in preprocessed_adata.layers
+ assert preprocessed_adata.layers["gamma"].shape == (n_obs, n_vars)
+ # Dynamic gamma should be non-negative (clipped)
+ assert np.all(preprocessed_adata.layers["gamma"] >= 0)
+
+
+def test_dynamic_mode_logs_params(preprocessed_adata):
+ """Dynamic mode logs mode and velocity_layer in uns."""
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+ n_obs, n_vars = preprocessed_adata.shape
+ preprocessed_adata.layers["velocity_S"] = np.random.randn(n_obs, n_vars).astype(
+ np.float32
+ )
+
+ scptr.tl.estimate_gamma(
+ preprocessed_adata, mode="dynamic", velocity_layer="velocity_S"
+ )
+
+ params = preprocessed_adata.uns["scptr"]["estimate_gamma"]
+ assert params["mode"] == "dynamic"
+ assert params["velocity_layer"] == "velocity_S"
+
+
+def test_dynamic_requires_velocity_layer(preprocessed_adata):
+ """Dynamic mode without velocity_layer raises ValueError."""
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+
+ with pytest.raises(ValueError, match="velocity_layer must be provided"):
+ scptr.tl.estimate_gamma(preprocessed_adata, mode="dynamic")
+
+
+def test_steady_state_mode_default(preprocessed_adata):
+ """Default mode is steady_state and works as before."""
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+ scptr.tl.estimate_gamma(preprocessed_adata)
+
+ params = preprocessed_adata.uns["scptr"]["estimate_gamma"]
+ assert params["mode"] == "steady_state"
+
+
+def test_unknown_mode_raises(preprocessed_adata):
+ """Unknown mode raises ValueError."""
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+
+ with pytest.raises(ValueError, match="Unknown mode"):
+ scptr.tl.estimate_gamma(preprocessed_adata, mode="invalid")
diff --git a/tests/test_integration.py b/tests/test_integration.py
new file mode 100644
index 0000000000000000000000000000000000000000..90f88aaa377ab87780b0e47136a3ea6853dd6da6
--- /dev/null
+++ b/tests/test_integration.py
@@ -0,0 +1,71 @@
+"""Integration test: full pipeline on synthetic data."""
+
+import numpy as np
+import pytest
+
+
+def test_full_pipeline(synthetic_adata):
+ """Run the complete scPTR pipeline on synthetic data."""
+ import scptr
+
+ adata = synthetic_adata
+
+ # Preprocessing
+ scptr.pp.filter_genes(adata, min_unspliced_counts=1, min_unspliced_cells=1)
+ scptr.pp.normalize_layers(adata)
+ scptr.pp.neighbors(adata, n_neighbors=30)
+ scptr.pp.smooth_layers(adata)
+
+ assert "Mu" in adata.layers
+ assert "Ms" in adata.layers
+
+ # Core estimation
+ scptr.tl.estimate_beta(adata)
+ scptr.tl.estimate_gamma(adata)
+ scptr.tl.variance_decomposition(adata)
+
+ assert "beta" in adata.var.columns
+ assert "gamma" in adata.layers
+ assert "tf_score" in adata.var.columns
+ assert "ptf_score" in adata.var.columns
+
+ # PT states
+ scptr.tl.pt_states(adata)
+ assert "pt_state" in adata.obs.columns
+ assert "X_gamma_pca" in adata.obsm
+ assert "X_gamma_umap" in adata.obsm
+
+ # Rank genes
+ result = scptr.tl.rank_pt_genes(adata)
+ assert len(result) > 0
+
+ # PT velocity
+ scptr.tl.pt_velocity(adata)
+ assert "pt_velocity" in adata.layers
+ assert adata.layers["pt_velocity"].shape == adata.shape
+
+ # Check all uns parameters logged
+ assert "scptr" in adata.uns
+ params = adata.uns["scptr"]
+ for step in [
+ "filter_genes", "normalize_layers", "neighbors",
+ "smooth_layers", "estimate_beta", "estimate_gamma",
+ "variance_decomposition", "pt_states", "rank_pt_genes",
+ "pt_velocity",
+ ]:
+ assert step in params, f"Missing params for {step}"
+
+
+def test_network_inference(analyzed_adata):
+ """Test network inference on analyzed data."""
+ import scptr
+
+ # Use a small subset of genes as regulators/targets for speed
+ genes = analyzed_adata.var_names[:20].tolist()
+ result = scptr.tl.infer_network(
+ analyzed_adata,
+ regulators=genes,
+ targets=genes[:5],
+ )
+ assert "pt_network" in analyzed_adata.uns
+ assert "infer_network" in analyzed_adata.uns["scptr"]
diff --git a/tests/test_network_priors.py b/tests/test_network_priors.py
new file mode 100644
index 0000000000000000000000000000000000000000..832040e05e326947240c8b4c9e5aee8309eec97e
--- /dev/null
+++ b/tests/test_network_priors.py
@@ -0,0 +1,105 @@
+"""Tests for prior-weighted network inference."""
+
+import numpy as np
+import pandas as pd
+import pytest
+
+
+def test_network_with_priors(analyzed_adata):
+ """Network inference with priors runs and returns DataFrame."""
+ import scptr
+
+ gene_names = analyzed_adata.var_names.tolist()
+ regulators = gene_names[:10]
+ targets = gene_names[10:15]
+
+ # Create a prior network
+ prior_rows = []
+ for reg in regulators[:3]:
+ for tgt in targets:
+ prior_rows.append({"regulator": reg, "target": tgt, "weight": 2.0})
+ prior_network = pd.DataFrame(prior_rows)
+
+ result = scptr.tl.infer_network(
+ analyzed_adata,
+ regulators=regulators,
+ targets=targets,
+ prior_network=prior_network,
+ )
+
+ assert isinstance(result, pd.DataFrame)
+ if len(result) > 0:
+ assert set(result.columns) == {"regulator", "target", "weight"}
+
+
+def test_network_without_priors_unchanged(analyzed_adata):
+ """Network inference without priors still works as before."""
+ import scptr
+
+ gene_names = analyzed_adata.var_names.tolist()
+ result = scptr.tl.infer_network(
+ analyzed_adata,
+ regulators=gene_names[:10],
+ targets=gene_names[10:15],
+ )
+
+ assert isinstance(result, pd.DataFrame)
+ params = analyzed_adata.uns["scptr"]["infer_network"]
+ assert params["has_prior"] is False
+
+
+def test_network_prior_logs_has_prior(analyzed_adata):
+ """Prior usage is logged in uns params."""
+ import scptr
+
+ gene_names = analyzed_adata.var_names.tolist()
+ prior_network = pd.DataFrame(
+ {"regulator": [gene_names[0]], "target": [gene_names[10]], "weight": [1.0]}
+ )
+
+ scptr.tl.infer_network(
+ analyzed_adata,
+ regulators=gene_names[:5],
+ targets=gene_names[10:12],
+ prior_network=prior_network,
+ )
+
+ params = analyzed_adata.uns["scptr"]["infer_network"]
+ assert params["has_prior"] is True
+
+
+def test_load_motif_priors_validates_columns(tmp_path):
+ """load_motif_priors raises on missing columns."""
+ import scptr
+
+ bad_csv = tmp_path / "bad.csv"
+ bad_csv.write_text("col_a,col_b\n1,2\n")
+
+ with pytest.raises(ValueError, match="missing required columns"):
+ scptr.tl.load_motif_priors(str(bad_csv))
+
+
+def test_load_motif_priors_valid(tmp_path):
+ """load_motif_priors loads a valid CSV."""
+ import scptr
+
+ csv_path = tmp_path / "priors.csv"
+ csv_path.write_text("regulator,target,weight\nA,B,1.5\nC,D,0.5\n")
+
+ df = scptr.tl.load_motif_priors(str(csv_path))
+ assert len(df) == 2
+ assert list(df.columns) == ["regulator", "target", "weight"]
+
+
+def test_list_known_rbps():
+ """list_known_rbps returns a non-empty list."""
+ import scptr
+
+ rbps = scptr.tl.list_known_rbps()
+ assert len(rbps) > 100
+
+ human_rbps = scptr.tl.list_known_rbps(organism="human")
+ mouse_rbps = scptr.tl.list_known_rbps(organism="mouse")
+ assert len(human_rbps) > 0
+ assert len(mouse_rbps) > 0
+ assert len(human_rbps) + len(mouse_rbps) == len(rbps)
diff --git a/tests/test_plotting.py b/tests/test_plotting.py
new file mode 100644
index 0000000000000000000000000000000000000000..ed84237acb1b8f4a66611dfd0803ee83375c24ca
--- /dev/null
+++ b/tests/test_plotting.py
@@ -0,0 +1,66 @@
+"""Smoke tests for plotting functions."""
+
+import matplotlib
+matplotlib.use("Agg")
+
+import pytest
+
+
+def test_phase_portrait(analyzed_adata):
+ import scptr
+
+ gene = analyzed_adata.var_names[0]
+ fig = scptr.pl.phase_portrait(analyzed_adata, gene, show=False)
+ assert fig is not None
+
+
+def test_gamma_heatmap(analyzed_adata):
+ import scptr
+
+ fig = scptr.pl.gamma_heatmap(analyzed_adata, show=False)
+ assert fig is not None
+
+
+def test_gamma_violin(analyzed_adata):
+ import scptr
+
+ gene = analyzed_adata.var_names[0]
+ fig = scptr.pl.gamma_violin(analyzed_adata, gene, show=False)
+ assert fig is not None
+
+
+def test_pt_umap(analyzed_adata):
+ import scptr
+
+ fig = scptr.pl.pt_umap(analyzed_adata, show=False)
+ assert fig is not None
+
+
+def test_pt_comparison(analyzed_adata):
+ import scptr
+
+ fig = scptr.pl.pt_comparison(analyzed_adata, show=False)
+ assert fig is not None
+
+
+def test_tf_ptf_scatter(analyzed_adata):
+ import scptr
+
+ fig = scptr.pl.tf_ptf_scatter(analyzed_adata, show=False)
+ assert fig is not None
+
+
+def test_pt_velocity_embedding(analyzed_adata):
+ import scptr
+
+ scptr.tl.pt_velocity(analyzed_adata)
+ fig = scptr.pl.pt_velocity_embedding(analyzed_adata, show=False)
+ assert fig is not None
+
+
+def test_pt_velocity_stream(analyzed_adata):
+ import scptr
+
+ scptr.tl.pt_velocity(analyzed_adata)
+ fig = scptr.pl.pt_velocity_stream(analyzed_adata, grid_size=20, show=False)
+ assert fig is not None
diff --git a/tests/test_preprocessing.py b/tests/test_preprocessing.py
new file mode 100644
index 0000000000000000000000000000000000000000..ddf34874a72f27a4280f2acdfa53eaefa416d515
--- /dev/null
+++ b/tests/test_preprocessing.py
@@ -0,0 +1,69 @@
+"""Tests for the preprocessing module."""
+
+import numpy as np
+import pytest
+from scipy.sparse import issparse
+
+
+def test_filter_genes(synthetic_adata):
+ import scptr
+
+ n_before = synthetic_adata.n_vars
+ scptr.pp.filter_genes(
+ synthetic_adata, min_unspliced_counts=10, min_unspliced_cells=10
+ )
+ assert synthetic_adata.n_vars <= n_before
+ assert synthetic_adata.n_vars > 0
+ assert "filter_genes" in synthetic_adata.uns["scptr"]
+
+
+def test_filter_cells(synthetic_adata):
+ import scptr
+
+ n_before = synthetic_adata.n_obs
+ scptr.pp.filter_cells(synthetic_adata, min_unspliced_counts=1)
+ assert synthetic_adata.n_obs <= n_before
+ assert synthetic_adata.n_obs > 0
+
+
+def test_normalize_layers(synthetic_adata):
+ import scptr
+
+ scptr.pp.normalize_layers(synthetic_adata)
+ # After normalization, layers should be dense float32
+ assert not issparse(synthetic_adata.layers["spliced"])
+ assert synthetic_adata.layers["spliced"].dtype == np.float32
+ assert not issparse(synthetic_adata.layers["unspliced"])
+ assert "normalize_layers" in synthetic_adata.uns["scptr"]
+
+
+def test_neighbors(synthetic_adata):
+ import scptr
+
+ scptr.pp.normalize_layers(synthetic_adata)
+ scptr.pp.neighbors(synthetic_adata, n_neighbors=10)
+ assert "distances" in synthetic_adata.obsp
+ assert "connectivities" in synthetic_adata.obsp
+ assert "neighbors" in synthetic_adata.uns["scptr"]
+
+
+def test_smooth_layers(synthetic_adata):
+ import scptr
+
+ scptr.pp.normalize_layers(synthetic_adata)
+ scptr.pp.neighbors(synthetic_adata, n_neighbors=10)
+ scptr.pp.smooth_layers(synthetic_adata)
+ assert "Mu" in synthetic_adata.layers
+ assert "Ms" in synthetic_adata.layers
+ assert synthetic_adata.layers["Mu"].shape == synthetic_adata.shape
+ assert synthetic_adata.layers["Ms"].shape == synthetic_adata.shape
+ assert synthetic_adata.layers["Mu"].dtype == np.float32
+
+
+def test_smooth_fixed_bandwidth(synthetic_adata):
+ import scptr
+
+ scptr.pp.normalize_layers(synthetic_adata)
+ scptr.pp.neighbors(synthetic_adata, n_neighbors=10)
+ scptr.pp.smooth_layers(synthetic_adata, bandwidth=1.0)
+ assert "Mu" in synthetic_adata.layers
diff --git a/tests/test_pt_states.py b/tests/test_pt_states.py
new file mode 100644
index 0000000000000000000000000000000000000000..0fbdba57aaacd3d618a99f92ffa04635e8611cdf
--- /dev/null
+++ b/tests/test_pt_states.py
@@ -0,0 +1,22 @@
+"""Tests for PT state discovery."""
+
+import numpy as np
+import pytest
+
+
+def test_pt_states(analyzed_adata):
+ assert "pt_state" in analyzed_adata.obs.columns
+ assert "X_gamma_pca" in analyzed_adata.obsm
+ assert "X_gamma_umap" in analyzed_adata.obsm
+ assert analyzed_adata.obs["pt_state"].dtype.name == "category"
+ n_states = analyzed_adata.obs["pt_state"].nunique()
+ assert n_states >= 1
+
+
+def test_rank_pt_genes(analyzed_adata):
+ import scptr
+
+ result = scptr.tl.rank_pt_genes(analyzed_adata, groupby="pt_state")
+ assert len(result) > 0
+ assert "names" in result.columns or "group" in result.columns
+ assert "rank_pt_genes" in analyzed_adata.uns["scptr"]
diff --git a/tests/test_readwrite.py b/tests/test_readwrite.py
new file mode 100644
index 0000000000000000000000000000000000000000..2fe6f9c9d7be215f5a66db286320b4b802bd1d9a
--- /dev/null
+++ b/tests/test_readwrite.py
@@ -0,0 +1,65 @@
+"""Tests for readwrite validation."""
+
+import warnings
+
+import numpy as np
+import pytest
+from anndata import AnnData
+from scipy.sparse import csr_matrix
+
+
+@pytest.fixture
+def tmp_h5ad_with_layers(tmp_path):
+ """Create a temporary h5ad file with unspliced/spliced layers."""
+ adata = AnnData(
+ X=csr_matrix(np.ones((10, 5), dtype=np.float32)),
+ layers={
+ "spliced": csr_matrix(np.ones((10, 5), dtype=np.float32)),
+ "unspliced": csr_matrix(np.ones((10, 5), dtype=np.float32)),
+ },
+ )
+ path = tmp_path / "with_layers.h5ad"
+ adata.write_h5ad(path)
+ return path
+
+
+@pytest.fixture
+def tmp_h5ad_without_layers(tmp_path):
+ """Create a temporary h5ad file without unspliced/spliced layers."""
+ adata = AnnData(X=csr_matrix(np.ones((10, 5), dtype=np.float32)))
+ path = tmp_path / "without_layers.h5ad"
+ adata.write_h5ad(path)
+ return path
+
+
+def test_read_h5ad_no_warning_with_layers(tmp_h5ad_with_layers):
+ """read_h5ad does not warn when layers are present."""
+ from scptr.readwrite import read_h5ad
+
+ with warnings.catch_warnings():
+ warnings.simplefilter("error")
+ adata = read_h5ad(str(tmp_h5ad_with_layers))
+
+ assert "unspliced" in adata.layers
+ assert "spliced" in adata.layers
+
+
+def test_read_h5ad_warns_missing_layers(tmp_h5ad_without_layers):
+ """read_h5ad warns when unspliced/spliced layers are missing."""
+ from scptr.readwrite import read_h5ad
+
+ with pytest.warns(UserWarning, match="missing expected layers"):
+ read_h5ad(str(tmp_h5ad_without_layers))
+
+
+def test_validate_layers_warns_partial(tmp_path):
+ """_validate_layers warns when only one layer is missing."""
+ from scptr.readwrite import _validate_layers
+
+ adata = AnnData(
+ X=csr_matrix(np.ones((10, 5), dtype=np.float32)),
+ layers={"spliced": csr_matrix(np.ones((10, 5), dtype=np.float32))},
+ )
+
+ with pytest.warns(UserWarning, match="unspliced"):
+ _validate_layers(adata)
diff --git a/tests/test_variance.py b/tests/test_variance.py
new file mode 100644
index 0000000000000000000000000000000000000000..7a910c87ca5a2f2ed115414b45a5c648886c246a
--- /dev/null
+++ b/tests/test_variance.py
@@ -0,0 +1,25 @@
+"""Tests for variance decomposition."""
+
+import numpy as np
+import pytest
+
+
+def test_variance_decomposition(preprocessed_adata):
+ import scptr
+
+ scptr.tl.estimate_beta(preprocessed_adata)
+ scptr.tl.estimate_gamma(preprocessed_adata)
+ scptr.tl.variance_decomposition(preprocessed_adata)
+
+ assert "tf_score" in preprocessed_adata.var.columns
+ assert "ptf_score" in preprocessed_adata.var.columns
+
+ tf = preprocessed_adata.var["tf_score"].values
+ ptf = preprocessed_adata.var["ptf_score"].values
+
+ # TF + PTF should sum to ~1
+ np.testing.assert_allclose(tf + ptf, 1.0, atol=1e-5)
+
+ # Scores should be in [0, 1]
+ assert np.all(tf >= 0) and np.all(tf <= 1)
+ assert np.all(ptf >= 0) and np.all(ptf <= 1)
diff --git a/web/README.md b/web/README.md
new file mode 100644
index 0000000000000000000000000000000000000000..252970f5cc52e7af3108bb1d7f0ad961f673eff8
--- /dev/null
+++ b/web/README.md
@@ -0,0 +1,27 @@
+# scPTR Web Interface
+
+Interactive web application for single-cell post-transcriptional regulatory decomposition.
+
+## Run locally
+
+```bash
+pip install streamlit
+streamlit run web/app.py
+```
+
+Opens at `http://localhost:8501`
+
+## Deploy (Streamlit Community Cloud)
+
+1. Push repository to GitHub
+2. Go to [share.streamlit.io](https://share.streamlit.io)
+3. Connect repo, set main file to `web/app.py`
+4. Deploy
+
+## Workflow
+
+1. **Load Data** — upload .h5ad or use built-in pancreas / dentate gyrus datasets
+2. **Preprocess** — filter genes, normalize, build kNN graph, smooth layers
+3. **Estimate Rates** — β via quantile regression, γ = β · u / s per cell
+4. **Discover PT States** — Leiden clustering in γ-space; PT velocity; RBP networks
+5. **Results** — UMAP visualization, gene rankings, download outputs
diff --git a/web/app.py b/web/app.py
new file mode 100644
index 0000000000000000000000000000000000000000..8ca1b8953c6d29f29f280f4b4fd95c467c66c2ea
--- /dev/null
+++ b/web/app.py
@@ -0,0 +1,2690 @@
+"""scPTR — Single-Cell Post-Transcriptional Regulatory Decomposition."""
+
+from __future__ import annotations
+
+import io
+import os
+import tempfile
+import traceback
+import warnings
+
+import matplotlib
+matplotlib.use("Agg")
+import json
+import matplotlib.pyplot as plt
+import numpy as np
+import pandas as pd
+import scanpy as sc
+import streamlit as st
+
+warnings.filterwarnings("ignore")
+
+import scptr # noqa: E402 — imported after matplotlib backend set
+
+st.set_page_config(
+ page_title="scPTR",
+ page_icon=None,
+ layout="wide",
+ initial_sidebar_state="expanded",
+)
+
+# ── CSS ───────────────────────────────────────────────────────────────────────
+st.markdown("""
+
+""", unsafe_allow_html=True)
+
+# ── session state ─────────────────────────────────────────────────────────────
+for k, v in {
+ "page": "home",
+ "step": 1,
+ "adata": None,
+ "dataset_name": None,
+ "preprocessed": False,
+ "estimated": False,
+ "states_done": False,
+ "velocity_done": False,
+ "network_done": False,
+ "_tmps": [],
+}.items():
+ if k not in st.session_state:
+ st.session_state[k] = v
+
+
+# ── helpers ───────────────────────────────────────────────────────────────────
+def go(step: int) -> None:
+ st.session_state.step = step
+
+def nav(page: str) -> None:
+ st.session_state.page = page
+
+def fig_png(fig: plt.Figure, dpi: int = 150) -> bytes:
+ buf = io.BytesIO()
+ fig.savefig(buf, format="png", dpi=dpi, bbox_inches="tight", facecolor="white")
+ buf.seek(0)
+ return buf.read()
+
+def make_tmp(suffix: str = ".h5ad") -> str:
+ fd, path = tempfile.mkstemp(suffix=suffix)
+ os.close(fd)
+ st.session_state._tmps.append(path)
+ return path
+
+def clean_tmps() -> None:
+ for p in st.session_state._tmps:
+ try:
+ os.unlink(p)
+ except Exception:
+ pass
+ st.session_state._tmps = []
+
+def mg(*metrics) -> str:
+ """metric_grid(*[(label, value, sub, cls?), ...])"""
+ cells = []
+ for m in metrics:
+ lbl, val, sub = m[0], m[1], m[2]
+ cls = m[3] if len(m) > 3 else ""
+ cells.append(
+ f''
+ f'
{lbl}
'
+ f'
{val}
'
+ f'
{sub}
'
+ f'
{"".join(cells)}
'
+
+def reset_downstream(from_step: int) -> None:
+ if from_step <= 1:
+ st.session_state.preprocessed = False
+ st.session_state.estimated = False
+ st.session_state.states_done = False
+ st.session_state.velocity_done = False
+ st.session_state.network_done = False
+ elif from_step <= 2:
+ st.session_state.estimated = False
+ st.session_state.states_done = False
+ st.session_state.velocity_done = False
+ st.session_state.network_done = False
+ elif from_step <= 3:
+ st.session_state.states_done = False
+ st.session_state.velocity_done = False
+ st.session_state.network_done = False
+
+
+# ── sidebar ───────────────────────────────────────────────────────────────────
+STEPS = ["Load Data", "Preprocess", "Estimate Rates", "Discover PT States", "Results"]
+
+with st.sidebar:
+ st.markdown(
+ ''
+ '
scPTR
'
+ '
Single-Cell Post-Transcriptional
Regulatory Decomposition
'
+ '
'
+ f'{st.session_state.dataset_name}
'
+ f'{_a.n_obs:,} cells · {_a.n_vars:,} genes
'
+ f'{_done_count}/3 steps complete'
+ f'
',
+ unsafe_allow_html=True,
+ )
+ if st.button("Resume Analysis →", use_container_width=True):
+ nav("analysis"); st.rerun()
+
+ if st.session_state.page == "analysis":
+ st.markdown('
', unsafe_allow_html=True)
+ st.markdown('', unsafe_allow_html=True)
+
+ step = st.session_state.step
+ done = {
+ 1: st.session_state.adata is not None,
+ 2: st.session_state.preprocessed,
+ 3: st.session_state.estimated,
+ 4: st.session_state.states_done,
+ }
+ for i, label in enumerate(STEPS, 1):
+ if i == step:
+ cls = "active"
+ elif done.get(i, False):
+ cls = "done"
+ else:
+ cls = ""
+ num = "✓" if (done.get(i, False) and i != step) else str(i)
+
+ # Clickable for completed steps and step 5 (always accessible after states)
+ can_jump = done.get(i, False) and i != step
+ if can_jump:
+ # Show step as a compact link button
+ col_btn, = st.columns([1])
+ if st.button(f"↩ {label}", key=f"jump_{i}", use_container_width=True):
+ go(i); st.rerun()
+ else:
+ st.markdown(
+ f'
'
+ f'
{num}
'
+ f'
{label}
'
+ f'
',
+ unsafe_allow_html=True,
+ )
+ st.markdown('
{"
".join(lines)}
',
+ unsafe_allow_html=True,
+ )
+
+
+# ── page routing ──────────────────────────────────────────────────────────────
+page = st.session_state.page
+
+
+# ══════════════════════════════════════════════════════════════════════════════
+# HOME PAGE
+# ══════════════════════════════════════════════════════════════════════════════
+if page == "home":
+ st.markdown(
+ ''
+ '
Single-cell post-transcriptional
regulatory decomposition
'
+ '
'
+ 'scPTR estimates per-cell, per-gene mRNA degradation rates from standard scRNA-seq '
+ 'spliced/unspliced counts. It uses the degradation rate γ as a primary analytical '
+ 'axis — complementary to RNA velocity — to discover expression-invisible cell states, '
+ 'compute post-transcriptional velocity, and infer RNA-binding protein networks.'
+ '
'
+ '
γig = βg · uig / sig
'
+ '
'
+ f'Analysis progress · {_pct:.0f}%
'
+ f'{bars}
'
+ f''
+ f'{st.session_state.dataset_name} — '
+ f'{st.session_state.adata.n_obs:,} cells · {st.session_state.adata.n_vars:,} genes
',
+ unsafe_allow_html=True,
+ )
+ if st.button("Resume →"):
+ nav("analysis"); st.rerun()
+
+ # Pipeline — dynamic done/active state
+ _s = st.session_state
+ _pipe_states = [
+ _s.adata is not None,
+ _s.preprocessed,
+ _s.estimated,
+ _s.states_done,
+ _s.states_done,
+ ]
+ _next_step = next((i for i, v in enumerate(_pipe_states) if not v), len(_pipe_states))
+ def _pipe_cls(i):
+ if _pipe_states[i]: return "done"
+ if i == _next_step: return "active-step"
+ return ""
+ def _pipe_icon(i):
+ return "✓ " if _pipe_states[i] else ""
+ st.markdown('Analysis pipeline
', unsafe_allow_html=True)
+ st.markdown(
+ ''
+ f'
{_pipe_icon(0)}01
Load Data
'
+ '
Upload .h5ad or use built-in pancreas / dentate gyrus datasets
'
+ f'
{_pipe_icon(1)}02
Preprocess
'
+ '
Filter genes, normalize counts, kNN graph, Gaussian smoothing
'
+ f'
{_pipe_icon(2)}03
Estimate Rates
'
+ '
β via quantile regression on u/s portraits; γ = β · u / s per cell
'
+ f'
{_pipe_icon(3)}04
PT States
'
+ '
Leiden clustering in γ-space; PT velocity; RBP–target networks
'
+ f'
{_pipe_icon(4)}05
Results
'
+ '
UMAP visualization, gene rankings, download outputs
'
+ '
Validation
', unsafe_allow_html=True)
+ _g = 'background:#eaf5ef'
+ st.markdown(
+ ''
+ '| Validation | Result |
|---|
'
+ ''
+ f'| sci-fate metabolic labeling | ρ = −0.81 |
'
+ f'| 10x developmental half-lives | ρ = −0.33 to −0.40 |
'
+ f'| vs. scVelo steady-state | −0.37 (scPTR: −0.40) |
'
+ f'| vs. velVI | −0.28 (scPTR: −0.40) |
'
+ f'| miRNA target enrichment | 59% of 215 families, p = 4.7×10⁻⁶⁵ |
'
+ f'| DepMap CRISPR essentiality | hub RBPs, p = 6.4×10⁻⁵ |
'
+ f'| Subsampling robustness | r > 0.97 at 20% |
'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+ with col2:
+ st.markdown('Key findings
', unsafe_allow_html=True)
+ st.markdown(
+ ''
+ '
Expression-invisible states
'
+ '
'
+ '3/8 pancreatic and 6/11 hippocampal cell types harbor post-transcriptional '
+ 'subpopulations undetectable by expression analysis. Confirmed by zero-permutation '
+ 'control (ARI ≈ 0).'
+ '
'
+ '
Temporal precedence
'
+ '
'
+ 'Degradation-rate changes precede expression changes for 54% of pancreas '
+ 'transition genes (p < 10⁻⁵⁷) and 78% in dentate gyrus (p = 9.9×10⁻¹³).'
+ '
'
+ '
RBP networks
'
+ '
'
+ 'Library-size-corrected inference identifies essential hub regulators '
+ '(HNRNPA1, YBX1, ELAVL1/HuR). Neuroblastoma shows 66% stabilizing edges.'
+ '
Input requirements
', unsafe_allow_html=True)
+ st.markdown(
+ ''
+ 'scPTR requires an AnnData file (.h5ad) with two count matrix layers: '
+ 'spliced and unspliced. These can be generated with '
+ 'STARsolo, Alevin-fry, kallisto|bustools, '
+ 'or velocyto. Raw (un-normalized) counts are expected.'
+ '
',
+ unsafe_allow_html=True,
+ )
+ st.markdown(
+ ''
+ 'Session data lives in browser memory. Keep this tab open while running analysis. '
+ 'Refreshing the page will reset all results. Download your AnnData file in step 5 to save progress.'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+
+# ══════════════════════════════════════════════════════════════════════════════
+# ANALYSIS — STEP 1: LOAD DATA
+# ══════════════════════════════════════════════════════════════════════════════
+elif page == "analysis" and st.session_state.step == 1:
+ st.markdown('Load Data — step 1 of 5
', unsafe_allow_html=True)
+ st.markdown(
+ 'Upload an AnnData file (.h5ad) containing spliced and '
+ 'unspliced count layers, or start with a built-in example dataset.
',
+ unsafe_allow_html=True,
+ )
+
+ st.markdown('Quick start
', unsafe_allow_html=True)
+ qs_c1, qs_c2, qs_c3 = st.columns(3, gap="large")
+ with qs_c1:
+ st.markdown(
+ ''
+ '
Pancreas
'
+ '
'
+ 'Mouse endocrinogenesis · 3,696 cells
'
+ 'Bastidas-Ponce et al. 2019'
+ '
'
+ '
Error: {e}
', unsafe_allow_html=True)
+ with qs_c2:
+ st.markdown(
+ ''
+ '
Dentate Gyrus
'
+ '
'
+ 'Mouse hippocampal neurogenesis · 2,930 cells
'
+ 'Hochgerner et al. 2018'
+ '
'
+ '
Error: {e}
', unsafe_allow_html=True)
+ with qs_c3:
+ st.markdown(
+ ''
+ '
Upload
'
+ '
'
+ 'Your own .h5ad file
'
+ 'Requires spliced + unspliced layers'
+ '
'
+ '
', unsafe_allow_html=True)
+
+ col1, col2 = st.columns(2, gap="large")
+
+ with col1:
+ st.markdown('Example datasets
', unsafe_allow_html=True)
+ example = st.selectbox(
+ "Dataset",
+ ["— select —",
+ "Pancreas (mouse endocrinogenesis, 3,696 cells)",
+ "Dentate Gyrus (mouse hippocampal neurogenesis, 2,930 cells)"],
+ label_visibility="collapsed",
+ )
+ st.markdown(
+ ''
+ 'Both datasets include spliced/unspliced counts from scVelo. '
+ 'Requires pooch — datasets are downloaded on first use (~30 MB each).'
+ '
',
+ unsafe_allow_html=True,
+ )
+ if st.button("Load Example Dataset", disabled=(example == "— select —")):
+ with st.spinner("Downloading and loading dataset…"):
+ try:
+ if "Pancreas" in example:
+ adata = scptr.datasets.pancreas()
+ name = "Pancreas"
+ else:
+ adata = scptr.datasets.dentate_gyrus()
+ name = "Dentate Gyrus"
+ st.session_state.adata = adata
+ st.session_state.dataset_name = name
+ reset_downstream(1)
+ go(2)
+ st.rerun()
+ except Exception as e:
+ st.markdown(
+ f'Error loading dataset: {e}
'
+ f'Ensure pip install "scptr[datasets]" is installed.
',
+ unsafe_allow_html=True,
+ )
+
+ with col2:
+ if st.session_state.pop("_show_upload", False):
+ st.markdown('Use the file uploader below to load your .h5ad file.
', unsafe_allow_html=True)
+ st.markdown('Upload your own
', unsafe_allow_html=True)
+ uploaded = st.file_uploader(
+ "H5AD file",
+ type=["h5ad"],
+ label_visibility="collapsed",
+ help="AnnData file with 'spliced' and 'unspliced' layers",
+ )
+ if uploaded is not None:
+ st.markdown(
+ f''
+ f'File: {uploaded.name} ({uploaded.size / 1e6:.1f} MB)
',
+ unsafe_allow_html=True,
+ )
+ if st.button("Load File"):
+ tmp = make_tmp(".h5ad")
+ try:
+ with open(tmp, "wb") as f:
+ f.write(uploaded.read())
+ with st.spinner("Reading file…"):
+ adata = sc.read_h5ad(tmp)
+
+ missing = [l for l in ["spliced", "unspliced"] if l not in adata.layers]
+ if missing:
+ st.markdown(
+ f'Missing layers: {", ".join(missing)}
'
+ f'The file must contain spliced and unspliced '
+ f'count matrix layers. Use velocyto, STARsolo, or Alevin-fry to generate them.
',
+ unsafe_allow_html=True,
+ )
+ else:
+ st.session_state.adata = adata
+ st.session_state.dataset_name = uploaded.name.removesuffix(".h5ad")
+ reset_downstream(1)
+ go(2)
+ st.rerun()
+ except Exception as e:
+ st.markdown(
+ f'Could not read file: {e}
',
+ unsafe_allow_html=True,
+ )
+
+ st.markdown('
', unsafe_allow_html=True)
+ st.markdown(
+ ''
+ '
What scPTR needs
'
+ '
'
+ '| Slot | Content | Required |
|---|
'
+ ''
+ '| adata.layers["spliced"] | Spliced (mature) mRNA counts per cell × gene | ✓ |
'
+ '| adata.layers["unspliced"] | Unspliced (nascent) mRNA counts per cell × gene | ✓ |
'
+ '| adata.obs columns | Cell metadata (cell type, cluster, etc.) for visualization | optional |
'
+ '| adata.obsm["X_umap"] | UMAP embedding (scPTR will compute one if absent) | optional |
'
+ '
'
+ '
Preprocess — step 2 of 5
', unsafe_allow_html=True)
+ st.markdown(
+ 'Filter low-quality genes, normalize counts to library size, '
+ 'build a cell neighborhood graph (kNN in PCA space), and apply Gaussian kernel '
+ 'smoothing to the spliced and unspliced layers.
',
+ unsafe_allow_html=True,
+ )
+
+ # Data quality summary
+ _s_layer = adata.layers["spliced"]
+ _u_layer = adata.layers["unspliced"]
+ _s_sparsity = 1.0 - float(np.count_nonzero(_s_layer)) / _s_layer.size
+ _u_sparsity = 1.0 - float(np.count_nonzero(_u_layer)) / _u_layer.size
+ _has_obs = list(adata.obs.columns)[:5]
+ st.markdown(
+ mg(
+ ("Cells", f"{adata.n_obs:,}", ""),
+ ("Genes", f"{adata.n_vars:,}", "before filtering"),
+ ("Spliced sparsity", f"{_s_sparsity:.1%}", "zeros in matrix"),
+ ("Unspliced sparsity", f"{_u_sparsity:.1%}", "zeros in matrix"),
+ ),
+ unsafe_allow_html=True,
+ )
+ _layer_ok = all(l in adata.layers for l in ["spliced", "unspliced"])
+ _extra_layers = [l for l in adata.layers if l not in ["spliced", "unspliced"]]
+ _layer_info = (
+ '✓ spliced '
+ '✓ unspliced'
+ )
+ if _extra_layers:
+ _layer_info += f' · also: {", ".join(_extra_layers[:4])}'
+ if _has_obs:
+ _layer_info += f'
obs columns: {", ".join(_has_obs)}'
+ st.markdown(
+ f''
+ f'Layers detected: {_layer_info}'
+ f'
',
+ unsafe_allow_html=True,
+ )
+
+ _rn = st.session_state.get("pp_reset_n", 0) # reset counter — changes keys to force re-init
+ col1, col2, col3 = st.columns(3, gap="large")
+ with col1:
+ st.markdown('Gene filtering
', unsafe_allow_html=True)
+ min_unspliced = st.number_input(
+ "Min total unspliced counts per gene",
+ value=10, min_value=1, step=1,
+ key=f"pp_mu_{_rn}",
+ help="Genes with fewer total unspliced counts across all cells are removed.",
+ )
+ min_cells = st.number_input(
+ "Min cells with nonzero unspliced",
+ value=5, min_value=1, step=1,
+ key=f"pp_mc_{_rn}",
+ help="Genes expressed in fewer cells are removed.",
+ )
+ with col2:
+ st.markdown('Cell filtering
', unsafe_allow_html=True)
+ min_cell_unspliced = st.number_input(
+ "Min unspliced counts per cell",
+ value=0, min_value=0, step=100,
+ key=f"pp_mcu_{_rn}",
+ help="Cells with fewer total unspliced counts are removed. 0 = no filter.",
+ )
+ min_cell_spliced = st.number_input(
+ "Min spliced counts per cell",
+ value=0, min_value=0, step=100,
+ key=f"pp_mcs_{_rn}",
+ help="Cells with fewer total spliced counts are removed. 0 = no filter.",
+ )
+ with col3:
+ st.markdown('Neighborhood graph
', unsafe_allow_html=True)
+ n_neighbors = st.number_input(
+ "Neighbors (kNN graph)",
+ value=30, min_value=5, max_value=100, step=5,
+ key=f"pp_nn_{_rn}",
+ help="Number of nearest neighbors for the cell graph. Larger = smoother.",
+ )
+ n_pcs = st.number_input(
+ "PCA components",
+ value=30, min_value=10, max_value=100, step=5,
+ key=f"pp_np_{_rn}",
+ help="PCA dimensions used for neighbor search.",
+ )
+
+ with st.expander("Advanced: Smoothing options"):
+ bw_mode = st.radio(
+ "Smoothing bandwidth",
+ ["Adaptive (median distance)", "Fixed value"],
+ horizontal=True,
+ )
+ fixed_bw = None
+ if bw_mode == "Fixed value":
+ fixed_bw = st.number_input("Bandwidth", value=1.0, min_value=0.05, step=0.05)
+ st.markdown(
+ ''
+ 'Gaussian kernel smoothing reduces noise in spliced/unspliced counts by averaging '
+ 'over cell neighbors. Adaptive bandwidth uses the median distance to the k-th neighbor.'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+ if st.session_state.preprocessed:
+ st.markdown(
+ 'Preprocessing already complete. '
+ 'Click below to re-run with new parameters.
',
+ unsafe_allow_html=True,
+ )
+
+ run_col, reset_col = st.columns([2, 1])
+ if "pp_reset_n" not in st.session_state:
+ st.session_state.pp_reset_n = 0
+ with reset_col:
+ if st.button("↻ Reset to defaults", help="Restore all preprocessing parameters to defaults"):
+ st.session_state.pp_reset_n += 1
+ st.rerun()
+ with run_col:
+ _run_pp = st.button("Run Preprocessing", use_container_width=True)
+ if _run_pp:
+ adata_work = st.session_state.adata.copy()
+ try:
+ prog = st.progress(0, text="Filtering genes…")
+ scptr.pp.filter_genes(
+ adata_work,
+ min_unspliced_counts=min_unspliced,
+ min_unspliced_cells=min_cells,
+ )
+ if min_cell_unspliced > 0 or min_cell_spliced > 0:
+ prog.progress(15, text="Filtering cells…")
+ scptr.pp.filter_cells(
+ adata_work,
+ min_unspliced_counts=min_cell_unspliced,
+ min_spliced_counts=min_cell_spliced,
+ )
+ prog.progress(25, text="Normalizing layers…")
+ scptr.pp.normalize_layers(adata_work)
+ prog.progress(50, text="Building neighborhood graph…")
+ scptr.pp.neighbors(adata_work, n_neighbors=n_neighbors, n_pcs=n_pcs)
+ prog.progress(75, text="Smoothing spliced/unspliced…")
+ if fixed_bw is not None:
+ scptr.pp.smooth_layers(adata_work, bandwidth=fixed_bw)
+ else:
+ scptr.pp.smooth_layers(adata_work)
+ prog.progress(100, text="Done.")
+
+ st.session_state.adata = adata_work
+ st.session_state.preprocessed = True
+ reset_downstream(2)
+
+ _cells_removed = adata.n_obs - adata_work.n_obs
+ _genes_removed = adata.n_vars - adata_work.n_vars
+ st.markdown(
+ mg(
+ ("Cells retained", f"{adata_work.n_obs:,}", f"−{_cells_removed:,} filtered" if _cells_removed else "all kept", "green"),
+ ("Genes retained", f"{adata_work.n_vars:,}", f"−{_genes_removed:,} filtered"),
+ ("Neighbors", str(n_neighbors), "kNN graph"),
+ ("PCA dims", str(n_pcs), "for graph"),
+ ),
+ unsafe_allow_html=True,
+ )
+ st.markdown(
+ ''
+ 'Preprocessing complete — genes filtered, layers normalized, kNN graph built, counts smoothed. '
+ 'Next: estimate β (splicing rate) and γ (degradation rate). '
+ 'Variance decomposition runs automatically with rate estimation.'
+ '
',
+ unsafe_allow_html=True,
+ )
+ except Exception as e:
+ st.markdown(
+ f'Preprocessing failed: {e}
'
+ f'Common causes: '
+ f'too few genes after filtering (lower thresholds in step 2) · '
+ f'missing spliced/unspliced layers · '
+ f'dataset too small for PCA (n_pcs may exceed n_cells or n_genes)'
+ f'
',
+ unsafe_allow_html=True,
+ )
+ with st.expander("Traceback"):
+ st.code(traceback.format_exc())
+
+ st.markdown('
', unsafe_allow_html=True)
+ c1, c2 = st.columns([1, 6])
+ with c1:
+ if st.button("← Back"):
+ go(1); st.rerun()
+ with c2:
+ if st.button("Next: Estimate Rates →", disabled=not st.session_state.preprocessed):
+ go(3); st.rerun()
+
+
+# ══════════════════════════════════════════════════════════════════════════════
+# ANALYSIS — STEP 3: ESTIMATE RATES
+# ══════════════════════════════════════════════════════════════════════════════
+elif page == "analysis" and st.session_state.step == 3:
+ adata = st.session_state.adata
+ st.markdown('Estimate Rates — step 3 of 5
', unsafe_allow_html=True)
+ st.markdown(
+ 'Estimate gene-specific splicing rates (β) from unspliced/spliced phase '
+ 'portraits using quantile regression. Then compute per-cell, per-gene degradation rates '
+ 'γig = βg · uig / sig using the '
+ 'kinetic steady-state model.
',
+ unsafe_allow_html=True,
+ )
+
+ col1, col2 = st.columns(2, gap="large")
+ with col1:
+ st.markdown('Beta estimation (β)
', unsafe_allow_html=True)
+ quantile = st.slider(
+ "Phase portrait quantile",
+ 0.80, 0.99, 0.95, 0.01,
+ help="Upper quantile of the u/s ratio distribution used to estimate β. "
+ "Typical: 0.95 for 10x Chromium; 0.90–0.92 for Smart-seq (denser coverage). "
+ "Lower values = more conservative boundary.",
+ )
+ min_r2 = st.slider(
+ "Min R² for beta fit",
+ 0.0, 0.90, 0.0, 0.05,
+ help="Genes with a phase portrait R² below this threshold are excluded.",
+ )
+ with col2:
+ st.markdown('Gamma estimation (γ)
', unsafe_allow_html=True)
+ min_spliced_thr = st.number_input(
+ "Min smoothed spliced (Ms) for γ",
+ value=0.01, min_value=0.001, step=0.005, format="%.3f",
+ help="Cells with Ms < threshold for a given gene receive γ = 0 (prevents division by near-zero).",
+ )
+ clip_q = st.slider(
+ "Gamma clip quantile",
+ 0.90, 1.00, 0.99, 0.01,
+ help="Per-gene clipping at this quantile to remove extreme outliers before analysis.",
+ )
+
+ if st.session_state.estimated:
+ st.markdown(
+ 'Rate estimation already complete. Re-run to update with new parameters.
',
+ unsafe_allow_html=True,
+ )
+
+ if st.button("Estimate β and γ"):
+ adata_work = st.session_state.adata
+ try:
+ prog = st.progress(0, text="Estimating splicing rates (β)…")
+ scptr.tl.estimate_beta(adata_work, quantile=quantile)
+ prog.progress(40, text="Estimating degradation rates (γ)…")
+ scptr.tl.estimate_gamma(
+ adata_work,
+ clip_quantile=clip_q,
+ min_spliced=min_spliced_thr,
+ )
+ prog.progress(80, text="Variance decomposition…")
+ scptr.tl.variance_decomposition(adata_work)
+ prog.progress(100, text="Done.")
+
+ st.session_state.adata = adata_work
+ st.session_state.estimated = True
+ reset_downstream(3)
+
+ beta = adata_work.var["beta"]
+ gamma = adata_work.layers["gamma"]
+ gamma_pos = gamma[gamma > 0]
+ inf_genes = int((np.median(gamma, axis=0) > 0).sum())
+
+ st.markdown(
+ mg(
+ ("Median β", f"{np.median(beta):.3f}", "splicing rate"),
+ ("Median γ", f"{np.median(gamma_pos):.4f}", "positive cells", "blue"),
+ ("Max γ", f"{np.max(gamma):.2f}", "clipped"),
+ ("Informative genes", f"{inf_genes:,}", "median γ > 0", "green"),
+ ),
+ unsafe_allow_html=True,
+ )
+
+ # Phase portrait for highest-β gene
+ top_gene = beta.idxmax()
+ fig, axes = plt.subplots(1, 2, figsize=(9, 3.8))
+
+ # Phase portrait
+ ax = axes[0]
+ Ms = adata_work.layers["Ms"][:, adata_work.var_names.get_loc(top_gene)]
+ Mu = adata_work.layers["Mu"][:, adata_work.var_names.get_loc(top_gene)]
+ ax.scatter(Ms, Mu, s=5, alpha=0.35, color="#2b5797", linewidths=0)
+ bv = adata_work.var.loc[top_gene, "beta"]
+ x = np.linspace(0, np.percentile(Ms, 99), 100)
+ ax.plot(x, bv * x, color="#c0392b", lw=1.5, label=f"β = {bv:.3f}")
+ ax.set_xlabel("Ms (smoothed spliced)", fontsize=10)
+ ax.set_ylabel("Mu (smoothed unspliced)", fontsize=10)
+ ax.set_title(f"Phase portrait: {top_gene}", fontsize=10, fontweight="bold")
+ ax.legend(fontsize=9, frameon=False)
+ ax.spines[["top", "right"]].set_visible(False)
+
+ # Beta distribution
+ ax2 = axes[1]
+ ax2.hist(beta, bins=50, color="#2b5797", alpha=0.7, linewidth=0)
+ ax2.axvline(np.median(beta), color="#c0392b", lw=1.5,
+ label=f"median = {np.median(beta):.3f}")
+ ax2.set_xlabel("β (splicing rate)", fontsize=10)
+ ax2.set_ylabel("Gene count", fontsize=10)
+ ax2.set_title("Distribution of β across genes", fontsize=10, fontweight="bold")
+ ax2.legend(fontsize=9, frameon=False)
+ ax2.spines[["top", "right"]].set_visible(False)
+
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+
+ # β quality summary
+ _beta_pos_pct = (beta > 0).mean() * 100
+ _gamma_pos_pct = (np.median(adata_work.layers["gamma"], axis=0) > 0).mean() * 100
+ _quality = "good" if _beta_pos_pct > 60 else "low"
+ _quality_color = "#2d7d4b" if _quality == "good" else "#d4860a"
+ st.markdown(
+ f''
+ f'Data quality: '
+ f'{_beta_pos_pct:.0f}% of genes have estimable β · '
+ f'{_gamma_pos_pct:.0f}% have estimable γ · '
+ f'{_quality.upper()}'
+ f'
',
+ unsafe_allow_html=True,
+ )
+
+ st.markdown(
+ ''
+ 'β and γ estimated, variance decomposition complete. '
+ 'Next: cluster cells in γ-space to discover PT states. '
+ 'Or explore the phase portrait below for individual genes.'
+ '
',
+ unsafe_allow_html=True,
+ )
+ except Exception as e:
+ st.markdown(
+ f'Rate estimation failed: {e}
',
+ unsafe_allow_html=True,
+ )
+ with st.expander("Traceback"):
+ st.code(traceback.format_exc())
+
+ # Phase portrait explorer (available once rates are estimated)
+ if st.session_state.estimated:
+ st.markdown('Phase portrait explorer
', unsafe_allow_html=True)
+ st.markdown(
+ ''
+ 'Inspect the unspliced vs spliced phase portrait for any gene, colored by γ. '
+ 'The diagonal line shows the estimated β slope. Cells above = accelerating; below = decelerating.'
+ '
',
+ unsafe_allow_html=True,
+ )
+ adata_est = st.session_state.adata
+ pp_col1, pp_col2 = st.columns([3, 1])
+ with pp_col1:
+ pp_gene = st.selectbox(
+ "Gene",
+ sorted(adata_est.var_names.tolist()),
+ key="pp_gene_select",
+ help="Select a gene to visualize its unspliced vs spliced phase portrait.",
+ )
+ with pp_col2:
+ pp_cmap = st.selectbox("Color", ["viridis", "plasma", "RdBu_r", "coolwarm"], key="pp_cmap",
+ help="Colormap for γ values in the phase portrait scatter.")
+ if st.button("Plot Phase Portrait", key="pp_btn"):
+ try:
+ fig = scptr.pl.phase_portrait(
+ adata_est, genes=pp_gene, color_by="gamma",
+ cmap=pp_cmap, show=False,
+ )
+ if fig is not None:
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+ except Exception as e:
+ st.markdown(f'Phase portrait failed: {e}
', unsafe_allow_html=True)
+
+ st.markdown('
', unsafe_allow_html=True)
+ c1, c2 = st.columns([1, 6])
+ with c1:
+ if st.button("← Back"):
+ go(2); st.rerun()
+ with c2:
+ if st.button("Next: Discover PT States →", disabled=not st.session_state.estimated):
+ go(4); st.rerun()
+
+
+# ══════════════════════════════════════════════════════════════════════════════
+# ANALYSIS — STEP 4: DISCOVER PT STATES
+# ══════════════════════════════════════════════════════════════════════════════
+elif page == "analysis" and st.session_state.step == 4:
+ adata = st.session_state.adata
+ st.markdown('Discover PT States — step 4 of 5
', unsafe_allow_html=True)
+ st.markdown(
+ 'Cluster cells in γ-space (PCA → kNN → Leiden) to reveal '
+ 'post-transcriptional states invisible to expression analysis. '
+ 'Optionally compute PT velocity and infer RBP–target regulatory networks.
',
+ unsafe_allow_html=True,
+ )
+
+ tab1, tab2, tab3 = st.tabs(["PT STATES", "PT VELOCITY", "RBP NETWORKS"])
+
+ # ── Tab 1: PT States ──────────────────────────────────────────────────────
+ with tab1:
+ col1, col2 = st.columns(2, gap="large")
+ with col1:
+ st.markdown('Dimensionality reduction
', unsafe_allow_html=True)
+ n_pcs_g = st.number_input(
+ "PCA dims (γ-space)",
+ value=20, min_value=5, max_value=50,
+ help="PCA components computed from the γ matrix before clustering.",
+ )
+ n_nbrs_g = st.number_input(
+ "Neighbors (γ-space kNN)",
+ value=15, min_value=5, max_value=50,
+ help="Number of nearest neighbors in γ-PCA space.",
+ )
+ with col2:
+ st.markdown('Leiden clustering
', unsafe_allow_html=True)
+ resolution = st.slider(
+ "Resolution",
+ 0.1, 2.0, 0.5, 0.05,
+ help="Higher resolution → more, smaller clusters. "
+ "Typical range: 0.3–0.8. Start at 0.5 and increase if clusters are too coarse.",
+ )
+ rand_seed = st.number_input("Random seed", value=42, step=1,
+ help="Random seed for reproducible clustering and UMAP.")
+
+ st.markdown(
+ ''
+ 'PT state discovery performs PCA on the γ matrix, builds a kNN graph in γ-PCA space, '
+ 'then runs Leiden community detection. The resulting clusters represent groups of cells '
+ 'with similar post-transcriptional programs — which may differ from their expression-based identity.'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+ if st.session_state.states_done:
+ n_s = adata.obs["pt_state"].nunique() if "pt_state" in adata.obs else "?"
+ st.markdown(
+ f'PT states already computed ({n_s} states). '
+ f'Re-run to update with new parameters.
',
+ unsafe_allow_html=True,
+ )
+
+ if st.button("Find PT States"):
+ try:
+ with st.spinner("Clustering cells in γ-space…"):
+ scptr.tl.pt_states(
+ adata,
+ n_pcs=n_pcs_g,
+ n_neighbors=n_nbrs_g,
+ resolution=resolution,
+ random_state=rand_seed,
+ )
+ st.session_state.adata = adata
+ st.session_state.states_done = True
+ st.session_state.velocity_done = False
+ st.session_state.network_done = False
+
+ n_states = adata.obs["pt_state"].nunique()
+ state_sizes = adata.obs["pt_state"].value_counts().sort_index()
+
+ st.markdown(
+ mg(
+ ("PT States", str(n_states), "Leiden clusters in γ-space", "blue"),
+ ("Largest state", f"{state_sizes.max():,}", "cells"),
+ ("Smallest state", f"{state_sizes.min():,}", "cells"),
+ ),
+ unsafe_allow_html=True,
+ )
+
+ # Side-by-side UMAP: γ-space vs expression
+ fig, axes = plt.subplots(1, 2, figsize=(10, 4.2))
+
+ # γ-space UMAP
+ coords_g = adata.obsm["X_gamma_umap"]
+ labels = adata.obs["pt_state"].values
+ unique_labels = sorted(set(labels), key=lambda x: int(x) if str(x).isdigit() else x)
+ cmap = plt.colormaps["tab20"].resampled(len(unique_labels))
+ label_map = {l: i for i, l in enumerate(unique_labels)}
+ c = [label_map[l] for l in labels]
+ sc_plot = axes[0].scatter(
+ coords_g[:, 0], coords_g[:, 1],
+ c=c, cmap=cmap, s=8, alpha=0.6, linewidths=0,
+ )
+ axes[0].set_title("PT states (γ-space UMAP)", fontsize=10, fontweight="bold")
+ axes[0].axis("off")
+ # legend
+ for l in unique_labels:
+ axes[0].scatter([], [], color=cmap(label_map[l]), label=str(l), s=20)
+ axes[0].legend(fontsize=8, frameon=False, ncol=2, loc="upper right")
+
+ # Expression UMAP (if available)
+ if "X_umap" in adata.obsm:
+ coords_e = adata.obsm["X_umap"]
+ axes[1].scatter(
+ coords_e[:, 0], coords_e[:, 1],
+ c=c, cmap=cmap, s=8, alpha=0.6, linewidths=0,
+ )
+ axes[1].set_title("PT states (expression UMAP)", fontsize=10, fontweight="bold")
+ axes[1].axis("off")
+ else:
+ axes[1].text(0.5, 0.5, "No expression UMAP\n(add X_umap to adata.obsm)",
+ ha="center", va="center", transform=axes[1].transAxes,
+ fontsize=10, color="#888")
+ axes[1].axis("off")
+
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+
+ # State size table
+ rows = "".join(
+ f"| State {s} | {n:,} | "
+ f'{n / len(adata.obs) * 100:.1f}% |
'
+ for s, n in state_sizes.items()
+ )
+ st.markdown(
+ f''
+ f'| PT State | Cells | % |
|---|
'
+ f'{rows}
',
+ unsafe_allow_html=True,
+ )
+ st.markdown(
+ 'PT state discovery complete. '
+ 'Proceed to Results or explore PT Velocity and RBP Networks.
',
+ unsafe_allow_html=True,
+ )
+ except Exception as e:
+ st.markdown(
+ f'PT state discovery failed: {e}
',
+ unsafe_allow_html=True,
+ )
+ with st.expander("Traceback"):
+ st.code(traceback.format_exc())
+
+ # ── Tab 2: PT Velocity ────────────────────────────────────────────────────
+ with tab2:
+ if not st.session_state.states_done:
+ st.markdown(
+ 'Run PT state discovery (Tab 1) before computing velocity.
',
+ unsafe_allow_html=True,
+ )
+ else:
+ st.markdown(
+ ''
+ 'Post-transcriptional velocity computes, for each cell, the weighted mean '
+ 'difference in γ from its neighbors: v[i,g] = Σ w_ij · (γ[j,g] − γ[i,g]). '
+ 'This captures the direction and magnitude of post-transcriptional change, '
+ 'orthogonal to RNA velocity.'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+ vel_c1, vel_c2 = st.columns(2, gap="large")
+ with vel_c1:
+ graph_choice = st.radio(
+ "Neighbor graph",
+ ["γ-space graph (from PT states)", "Expression-space graph"],
+ horizontal=False,
+ help="Which kNN graph to use when averaging neighbor γ values.",
+ )
+ use_graph = "gamma" if "γ-space" in graph_choice else "expression"
+ with vel_c2:
+ viz_style = st.radio(
+ "Visualization style",
+ ["Arrows (embedding)", "Streamlines"],
+ horizontal=False,
+ help="Arrows show per-cell velocity; streamlines show flow patterns.",
+ )
+ arrow_size = st.slider("Arrow size", 1.0, 8.0, 3.0, 0.5, key="vel_arrow",
+ help="Scale of velocity arrows on the embedding plot.")
+
+ if st.session_state.velocity_done:
+ st.markdown(
+ 'PT velocity already computed. Re-run to update.
',
+ unsafe_allow_html=True,
+ )
+
+ if st.button("Compute PT Velocity"):
+ try:
+ with st.spinner("Computing PT velocity…"):
+ scptr.tl.pt_velocity(adata, use_graph=use_graph)
+ st.session_state.adata = adata
+ st.session_state.velocity_done = True
+
+ fig, ax = plt.subplots(figsize=(6, 5))
+ try:
+ if "Stream" in viz_style:
+ scptr.pl.pt_velocity_stream(adata, ax=ax, show=False)
+ else:
+ scptr.pl.pt_velocity_embedding(adata, ax=ax, arrow_size=arrow_size, show=False)
+ except Exception:
+ coords = adata.obsm.get("X_gamma_umap", adata.obsm.get("X_umap"))
+ if coords is not None:
+ ax.scatter(coords[:, 0], coords[:, 1], s=6, alpha=0.4,
+ color="#2b5797", linewidths=0)
+ ax.set_title(f"Post-transcriptional velocity ({'streamlines' if 'Stream' in viz_style else 'arrows'})", fontsize=10)
+ ax.axis("off")
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+
+ st.markdown(
+ 'PT velocity computed and stored in '
+ 'adata.layers["pt_velocity"].
',
+ unsafe_allow_html=True,
+ )
+ except Exception as e:
+ st.markdown(
+ f'PT velocity failed: {e}
',
+ unsafe_allow_html=True,
+ )
+ with st.expander("Traceback"):
+ st.code(traceback.format_exc())
+
+ # ── Tab 3: RBP Networks ───────────────────────────────────────────────────
+ with tab3:
+ if not st.session_state.states_done:
+ st.markdown(
+ 'Run PT state discovery (Tab 1) before inferring networks.
',
+ unsafe_allow_html=True,
+ )
+ else:
+ st.markdown(
+ ''
+ 'RBP–target network inference regresses γ of each target gene on the '
+ 'smoothed expression of regulator genes using elastic net regression. '
+ 'Non-zero coefficients indicate putative regulatory relationships. '
+ 'Runtime scales with number of genes — start with defaults for speed.'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+ # Core settings
+ use_known_rbps = st.checkbox(
+ "Restrict regulators to known RBPs (recommended — faster, more interpretable)",
+ value=True,
+ help="Filter regulators to curated RNA-binding proteins only.",
+ )
+ rbp_organism = None
+ if use_known_rbps:
+ rbp_organism = st.selectbox(
+ "RBP organism",
+ ["human", "mouse", None],
+ format_func=lambda x: x if x else "all species",
+ key="rbp_org",
+ )
+
+ with st.expander("Advanced options"):
+ net_c1, net_c2 = st.columns(2, gap="large")
+ with net_c1:
+ n_top = st.number_input(
+ "Top edges per target gene",
+ value=50, min_value=5, max_value=500,
+ help="Maximum number of regulator–target edges to retain per gene.",
+ )
+ alpha = st.slider(
+ "Elastic net mixing (α)",
+ 0.0, 1.0, 0.5, 0.05,
+ help="0 = ridge (all regulators retained), 1 = lasso (sparse selection). 0.5 = elastic net.",
+ )
+ with net_c2:
+ custom_regs = st.text_area(
+ "Additional regulators (optional)",
+ value="",
+ height=80,
+ help="Comma or newline-separated gene names. Appended to known RBPs if that option is checked.",
+ )
+ custom_tgts = st.text_area(
+ "Restrict to these targets (optional)",
+ value="",
+ height=80,
+ help="Leave empty to use all genes as targets.",
+ )
+
+ if st.session_state.network_done:
+ net = adata.uns.get("pt_network", pd.DataFrame())
+ st.markdown(
+ f'Network already inferred ({len(net):,} edges). '
+ f'Re-run to update.
',
+ unsafe_allow_html=True,
+ )
+
+ if st.button("Infer RBP–Target Network"):
+ regs = None
+ tgts = None
+ # Build regulator list
+ if use_known_rbps:
+ try:
+ known = scptr.tl.list_known_rbps(organism=rbp_organism if use_known_rbps else None)
+ # Keep only those present in adata
+ known = [g for g in known if g in adata.var_names]
+ regs = known if known else None
+ except Exception:
+ regs = None
+ if custom_regs.strip():
+ extra = [g.strip() for g in custom_regs.replace(",", "\n").split("\n") if g.strip()]
+ regs = list(set((regs or []) + extra)) if regs else extra
+ if custom_tgts.strip():
+ tgts = [g.strip() for g in custom_tgts.replace(",", "\n").split("\n") if g.strip()]
+ if regs:
+ st.markdown(
+ f'Using {len(regs):,} regulators.
',
+ unsafe_allow_html=True,
+ )
+
+ try:
+ with st.spinner("Running elastic net regression… (may take several minutes for large datasets)"):
+ scptr.tl.infer_network(
+ adata,
+ regulators=regs,
+ targets=tgts,
+ method="elasticnet",
+ alpha=alpha,
+ n_top=n_top,
+ )
+ st.session_state.adata = adata
+ st.session_state.network_done = True
+
+ net = adata.uns.get("pt_network", pd.DataFrame())
+ if len(net) == 0:
+ st.markdown(
+ 'No significant edges found. '
+ 'Try reducing α or increasing n_top.
',
+ unsafe_allow_html=True,
+ )
+ else:
+ n_destab = int((net["weight"] > 0).sum())
+ n_stab = int((net["weight"] < 0).sum())
+ st.markdown(
+ mg(
+ ("Total edges", f"{len(net):,}", "regulator–target pairs"),
+ ("Destabilizing", f"{n_destab:,}", "weight > 0", "blue"),
+ ("Stabilizing", f"{n_stab:,}", "weight < 0", "green"),
+ ("Hub regulators", f"{net['regulator'].nunique():,}", "unique"),
+ ),
+ unsafe_allow_html=True,
+ )
+ st.markdown(
+ ''
+ 'Edge weights: positive = regulator destabilizes target (promotes degradation); '
+ 'negative = regulator stabilizes target (protects from degradation).'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+ # Hub table with direction
+ hubs_dest = net[net["weight"] > 0].groupby("regulator").size()
+ hubs_stab = net[net["weight"] < 0].groupby("regulator").size()
+ hubs_all = net.groupby("regulator").size().sort_values(ascending=False).head(15)
+ rows = "".join(
+ f"| {rbp} | {cnt:,} | "
+ f"{hubs_dest.get(rbp, 0):,} | "
+ f"{hubs_stab.get(rbp, 0):,} |
"
+ for rbp, cnt in hubs_all.items()
+ )
+ st.markdown(
+ f''
+ f'| Regulator | Total | Destab. | Stab. |
|---|
'
+ f'{rows}
',
+ unsafe_allow_html=True,
+ )
+
+ # Network plot
+ try:
+ fig, ax = plt.subplots(figsize=(7, 6))
+ scptr.pl.network_graph(adata, n_edges=60, ax=ax, show=False)
+ ax.set_title("Top regulatory edges", fontsize=10, fontweight="bold")
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+ except Exception as _ne:
+ st.markdown(
+ f'Network plot could not be rendered: {_ne}
',
+ unsafe_allow_html=True,
+ )
+
+ st.markdown(
+ 'Network inference complete. '
+ 'Results stored in adata.uns["pt_network"].
',
+ unsafe_allow_html=True,
+ )
+ except Exception as e:
+ st.markdown(
+ f'Network inference failed: {e}
',
+ unsafe_allow_html=True,
+ )
+ with st.expander("Traceback"):
+ st.code(traceback.format_exc())
+
+ st.markdown('
', unsafe_allow_html=True)
+ c1, c2 = st.columns([1, 6])
+ with c1:
+ if st.button("← Back"):
+ go(3); st.rerun()
+ with c2:
+ if st.button("View Results →", disabled=not st.session_state.states_done):
+ go(5); st.rerun()
+
+
+# ══════════════════════════════════════════════════════════════════════════════
+# ANALYSIS — STEP 5: RESULTS
+# ══════════════════════════════════════════════════════════════════════════════
+elif page == "analysis" and st.session_state.step == 5:
+ adata = st.session_state.adata
+ st.markdown('Results — step 5 of 5
', unsafe_allow_html=True)
+
+ # Summary metrics
+ gamma = adata.layers.get("gamma")
+ gamma_pos = gamma[gamma > 0] if gamma is not None else np.array([])
+ n_states = adata.obs["pt_state"].nunique() if "pt_state" in adata.obs else 0
+ beta = adata.var.get("beta")
+ net = adata.uns.get("pt_network", pd.DataFrame())
+
+ st.markdown(
+ mg(
+ ("Cells", f"{adata.n_obs:,}", ""),
+ ("Genes", f"{adata.n_vars:,}", ""),
+ ("PT States", str(n_states), "γ-space Leiden", "blue"),
+ ("Median β", f"{np.median(beta):.3f}" if beta is not None else "—", "splicing rate"),
+ ("Median γ", f"{np.median(gamma_pos):.4f}" if len(gamma_pos) else "—", "positive cells"),
+ ("Network edges", f"{len(net):,}" if len(net) else "—", "RBP–target", "green"),
+ ),
+ unsafe_allow_html=True,
+ )
+
+ # Analysis completion summary
+ _done_items = []
+ if beta is not None: _done_items.append("β estimated")
+ if gamma is not None: _done_items.append("γ estimated")
+ if "tf_score" in adata.var.columns: _done_items.append("variance decomposed")
+ if n_states > 0: _done_items.append(f"{n_states} PT states")
+ if st.session_state.velocity_done: _done_items.append("PT velocity")
+ if st.session_state.network_done: _done_items.append(f"{len(net):,} network edges")
+ if _done_items:
+ st.markdown(
+ ''
+ f'Analyses complete: {" · ".join(_done_items)}'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+ rtab1, rtab2, rtab3, rtab4, rtab5 = st.tabs(["VISUALIZATION", "VARIANCE DECOMP", "GENE RANKINGS", "GAMMA EXPLORER", "DOWNLOAD"])
+
+ # ── Visualization ─────────────────────────────────────────────────────────
+ with rtab1:
+ st.markdown(
+ 'Choose a column to color by and click Plot UMAP to visualize cells. '
+ 'Toggle γ-space UMAP to compare expression vs. post-transcriptional organization.
',
+ unsafe_allow_html=True,
+ )
+ col_a, col_b = st.columns([2, 1])
+ with col_a:
+ color_opts = []
+ if "pt_state" in adata.obs.columns:
+ color_opts.append("pt_state")
+ color_opts += [c for c in adata.obs.columns if c != "pt_state"][:30]
+ viz_col = st.selectbox("Color by", color_opts, label_visibility="visible")
+ with col_b:
+ use_g_umap = st.checkbox(
+ "γ-space UMAP",
+ value=True,
+ help="Use UMAP computed from γ-space PCA (vs. expression UMAP)",
+ )
+
+ if st.button("Plot UMAP"):
+ basis = "X_gamma_umap" if (use_g_umap and "X_gamma_umap" in adata.obsm) else "X_umap"
+ if basis not in adata.obsm and "X_umap" not in adata.obsm:
+ with st.spinner("Computing expression UMAP…"):
+ sc.tl.umap(adata)
+ basis = "X_umap"
+ elif basis not in adata.obsm:
+ basis = "X_umap"
+
+ fig, ax = plt.subplots(figsize=(6, 5))
+ sc.pl.embedding(
+ adata, basis=basis, color=viz_col, ax=ax, show=False,
+ frameon=False, size=14,
+ title=f"{viz_col} · {'γ-space' if 'gamma' in basis else 'expression'} UMAP",
+ )
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+
+ # PT state UMAP using native scptr function
+ if n_states > 0 and "X_gamma_umap" in adata.obsm:
+ st.markdown('
', unsafe_allow_html=True)
+ if st.button("PT State UMAP (γ-space)"):
+ try:
+ fig = scptr.pl.pt_umap(adata, show=False)
+ if fig is not None:
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+ except Exception as e:
+ st.markdown(f'PT UMAP failed: {e}
', unsafe_allow_html=True)
+
+ if gamma is not None and n_states > 0:
+ st.markdown('
', unsafe_allow_html=True)
+ if st.button("Plot Gamma Heatmap"):
+ with st.spinner("Building heatmap…"):
+ try:
+ fig = scptr.pl.gamma_heatmap(adata, groupby="pt_state", show=False)
+ if fig is not None:
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+ except Exception as e:
+ st.markdown(f'Heatmap failed: {e}
', unsafe_allow_html=True)
+
+ if "X_gamma_umap" in adata.obsm and "X_umap" in adata.obsm:
+ st.markdown('
', unsafe_allow_html=True)
+ if st.button("γ-space vs Expression Comparison"):
+ with st.spinner("Building side-by-side comparison…"):
+ try:
+ fig = scptr.pl.pt_comparison(adata, figsize=(12, 5), show=False)
+ if fig:
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+ except Exception as e:
+ # Fallback: manual side-by-side
+ fig, axes = plt.subplots(1, 2, figsize=(12, 5))
+ for ax, basis, title in [
+ (axes[0], "X_umap", "Expression UMAP"),
+ (axes[1], "X_gamma_umap", "γ-space UMAP"),
+ ]:
+ coords = adata.obsm[basis]
+ if "pt_state" in adata.obs.columns:
+ labels = adata.obs["pt_state"].values
+ unique = sorted(set(labels), key=lambda x: int(x) if str(x).isdigit() else x)
+ cmap = plt.colormaps["tab20"].resampled(len(unique))
+ lmap = {l: i for i, l in enumerate(unique)}
+ c = [lmap[l] for l in labels]
+ ax.scatter(coords[:, 0], coords[:, 1], c=c, cmap=cmap,
+ s=8, alpha=0.6, linewidths=0)
+ else:
+ ax.scatter(coords[:, 0], coords[:, 1], s=8, alpha=0.5,
+ color="#2b5797", linewidths=0)
+ ax.set_title(title, fontsize=10, fontweight="bold")
+ ax.axis("off")
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+
+ if st.session_state.velocity_done:
+ st.markdown('
', unsafe_allow_html=True)
+ if st.button("Plot PT Velocity"):
+ try:
+ fig, ax = plt.subplots(figsize=(6, 5))
+ scptr.pl.pt_velocity_embedding(adata, ax=ax, show=False)
+ ax.set_title("Post-transcriptional velocity", fontsize=10)
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+ except Exception as e:
+ st.markdown(f'Velocity plot failed: {e}
', unsafe_allow_html=True)
+
+ # ── Variance decomposition ────────────────────────────────────────────────
+ with rtab2:
+ has_vd = "tf_score" in adata.var.columns and "ptf_score" in adata.var.columns
+ if not has_vd:
+ st.markdown(
+ 'Variance decomposition not computed. '
+ 'Return to step 3 and run Estimate β and γ (variance decomposition runs automatically).
',
+ unsafe_allow_html=True,
+ )
+ else:
+ st.markdown(
+ ''
+ 'Each gene\'s variance is decomposed into a transcriptional fraction (TF, driven by changes in '
+ 'unspliced/nascent RNA) and a post-transcriptional fraction (PTF, driven by changes in γ). '
+ 'Genes with high PTF score are primarily regulated post-transcriptionally.'
+ '
',
+ unsafe_allow_html=True,
+ )
+
+ tf = adata.var["tf_score"]
+ ptf = adata.var["ptf_score"]
+
+ # Aggregate stats
+ ptf_dom = (ptf > 0.5).sum()
+ tf_dom = (tf > 0.5).sum()
+ st.markdown(
+ mg(
+ ("PTF-dominant genes", f"{ptf_dom:,}", "PTF score > 0.5", "blue"),
+ ("TF-dominant genes", f"{tf_dom:,}", "TF score > 0.5"),
+ ("Median PTF score", f"{ptf.median():.3f}", "across genes"),
+ ),
+ unsafe_allow_html=True,
+ )
+
+ n_label = st.slider("Label top N genes", 5, 30, 10, 5, key="vd_label")
+ if st.button("Plot Variance Decomposition"):
+ try:
+ fig = scptr.pl.tf_ptf_scatter(adata, label_top=n_label, show=False)
+ if fig:
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+ except Exception as e:
+ # Fallback: manual plot
+ fig, axes = plt.subplots(1, 2, figsize=(10, 4.5))
+ axes[0].hist(ptf, bins=50, color="#2b5797", alpha=0.75, linewidth=0)
+ axes[0].axvline(0.5, color="#c0392b", lw=1.5, ls="--", label="PTF=0.5")
+ axes[0].set_xlabel("PTF score", fontsize=10)
+ axes[0].set_ylabel("Gene count", fontsize=10)
+ axes[0].set_title("Distribution of PTF scores", fontsize=10, fontweight="bold")
+ axes[0].legend(fontsize=9, frameon=False)
+ axes[0].spines[["top","right"]].set_visible(False)
+
+ rank = np.argsort(ptf.values)
+ axes[1].scatter(range(len(ptf)), ptf.values[rank], s=4, alpha=0.5,
+ color="#2b5797", linewidths=0)
+ axes[1].axhline(0.5, color="#c0392b", lw=1.2, ls="--")
+ axes[1].set_xlabel("Gene rank", fontsize=10)
+ axes[1].set_ylabel("PTF score", fontsize=10)
+ axes[1].set_title("Ranked PTF scores", fontsize=10, fontweight="bold")
+ axes[1].spines[["top","right"]].set_visible(False)
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+
+ # Top PTF genes table
+ st.markdown('Top post-transcriptionally regulated genes
', unsafe_allow_html=True)
+ top_ptf = ptf.sort_values(ascending=False).head(30)
+ ptf_df = pd.DataFrame({
+ "Gene": top_ptf.index,
+ "PTF score": top_ptf.values.round(4),
+ "TF score": tf[top_ptf.index].values.round(4),
+ })
+ st.dataframe(ptf_df, use_container_width=True, hide_index=True, height=420)
+
+ # ── Gene rankings ─────────────────────────────────────────────────────────
+ with rtab3:
+ if n_states == 0:
+ st.markdown(
+ 'No PT states found. Run Discover PT States → PT STATES tab first, '
+ 'then return here to rank differentially degraded genes.
',
+ unsafe_allow_html=True,
+ )
+ else:
+ st.markdown(
+ 'Identifies genes with significantly different γ (degradation rate) '
+ 'between PT states — analogous to differential expression but in γ-space.
',
+ unsafe_allow_html=True,
+ )
+ rank_method = st.selectbox(
+ "Statistical test",
+ ["t-test", "wilcoxon"],
+ help="t-test is faster; Wilcoxon rank-sum is more robust to outliers.",
+ )
+ if st.button("Rank PT-Differential Genes"):
+ with st.spinner("Running differential γ test…"):
+ try:
+ scptr.tl.rank_pt_genes(adata, method=rank_method)
+ st.session_state.adata = adata
+ except Exception as e:
+ st.markdown(f'Ranking failed: {e}
', unsafe_allow_html=True)
+
+ if "rank_pt_genes" in adata.uns:
+ names = adata.uns["rank_pt_genes"].get("names", {})
+ if names:
+ groups = list(names.keys())
+ show_groups = st.multiselect(
+ "Show states",
+ groups,
+ default=groups[:min(4, len(groups))],
+ )
+ if show_groups:
+ top_n_genes = st.slider("Genes per state", 5, 50, 15, 5, key="rank_n")
+ all_rows = []
+ for g in show_groups:
+ gene_list = list(names[g])[:top_n_genes]
+ for rank, gene in enumerate(gene_list, 1):
+ all_rows.append({"State": f"PT {g}", "Rank": rank, "Gene": gene})
+ if all_rows:
+ rank_df = pd.DataFrame(all_rows)
+ st.dataframe(rank_df, use_container_width=True, hide_index=True, height=380)
+ st.download_button(
+ "Download ranked genes (.csv)",
+ rank_df.to_csv(index=False).encode(),
+ file_name=f"ranked_genes_{st.session_state.dataset_name}.csv",
+ mime="text/csv",
+ )
+
+ if beta is not None:
+ st.markdown('
', unsafe_allow_html=True)
+ st.markdown('Genes by splicing rate (β)
', unsafe_allow_html=True)
+ top_n = st.slider("Show top N genes", 10, 100, 30, 10, key="top_beta_n")
+ top_beta = beta.sort_values(ascending=False).head(top_n)
+ beta_df = pd.DataFrame({"Gene": top_beta.index, "β (splicing rate)": top_beta.values.round(5)})
+ st.dataframe(beta_df, use_container_width=True, hide_index=True, height=350)
+
+ # ── Gamma explorer ────────────────────────────────────────────────────────
+ with rtab4:
+ if gamma is None:
+ st.markdown('No γ data available.
', unsafe_allow_html=True)
+ else:
+ st.markdown(
+ 'Explore the distribution of degradation rates for individual genes '
+ 'or compare γ across PT states.
',
+ unsafe_allow_html=True,
+ )
+ ge_col1, ge_col2 = st.columns([2, 1])
+ with ge_col1:
+ gene_input = st.selectbox(
+ "Select gene",
+ sorted(adata.var_names.tolist()),
+ key="gamma_gene",
+ )
+ with ge_col2:
+ groupby_col = "pt_state" if "pt_state" in adata.obs.columns else None
+ if groupby_col is None:
+ st.markdown('No PT states computed yet
', unsafe_allow_html=True)
+
+ if gene_input and st.button("Plot γ for selected gene"):
+ g_idx = adata.var_names.get_loc(gene_input)
+ g_vals = gamma[:, g_idx]
+ g_pos = g_vals[g_vals > 0]
+
+ # Try scptr.pl.gamma_violin first, fall back to manual
+ if groupby_col:
+ try:
+ fig = scptr.pl.gamma_violin(adata, genes=gene_input, groupby=groupby_col, show=False)
+ if fig:
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+ raise StopIteration # skip fallback
+ except StopIteration:
+ pass
+ except Exception:
+ pass # fall through to manual
+
+ # Manual histogram + violin fallback
+ fig, axes = plt.subplots(1, 2 if groupby_col else 1, figsize=(9 if groupby_col else 5, 3.8))
+ ax0 = axes[0] if groupby_col else axes
+
+ ax0.hist(g_pos, bins=40, color="#2b5797", alpha=0.75, linewidth=0)
+ if len(g_pos):
+ ax0.axvline(np.median(g_pos), color="#c0392b", lw=1.5,
+ label=f"median = {np.median(g_pos):.4f}")
+ ax0.legend(fontsize=9, frameon=False)
+ ax0.set_xlabel(f"γ ({gene_input})", fontsize=10)
+ ax0.set_ylabel("Cell count", fontsize=10)
+ ax0.set_title(f"γ distribution: {gene_input}", fontsize=10, fontweight="bold")
+ ax0.spines[["top", "right"]].set_visible(False)
+
+ if groupby_col:
+ states = sorted(adata.obs[groupby_col].unique(),
+ key=lambda x: int(x) if str(x).isdigit() else x)
+ data_by_state = [g_vals[adata.obs[groupby_col] == s] for s in states]
+ vp = axes[1].violinplot(data_by_state, positions=range(len(states)),
+ showmedians=True, showextrema=False)
+ for body in vp["bodies"]:
+ body.set_facecolor("#2b5797"); body.set_alpha(0.6)
+ vp["cmedians"].set_color("#c0392b")
+ axes[1].set_xticks(range(len(states)))
+ axes[1].set_xticklabels([str(s) for s in states], fontsize=9)
+ axes[1].set_xlabel("PT State", fontsize=10)
+ axes[1].set_ylabel(f"γ ({gene_input})", fontsize=10)
+ axes[1].set_title("γ by PT state", fontsize=10, fontweight="bold")
+ axes[1].spines[["top", "right"]].set_visible(False)
+
+ plt.tight_layout()
+ st.image(fig_png(fig), use_container_width=True)
+ plt.close(fig)
+
+ st.markdown(
+ mg(
+ ("Median γ", f"{np.median(g_pos):.4f}" if len(g_pos) else "—", "positive cells"),
+ ("Max γ", f"{np.max(g_vals):.4f}", ""),
+ ("Cells γ > 0", f"{int((g_vals > 0).sum()):,}", f"of {adata.n_obs:,}"),
+ ),
+ unsafe_allow_html=True,
+ )
+
+ # ── Download ──────────────────────────────────────────────────────────────
+ with rtab5:
+ st.markdown('Export results
', unsafe_allow_html=True)
+
+ col1, col2, col3 = st.columns(3)
+
+ with col1:
+ st.markdown("**Full AnnData**")
+ st.markdown(
+ ''
+ 'All layers (γ, β, Ms, Mu) plus PT state assignments and embeddings.
',
+ unsafe_allow_html=True,
+ )
+ if st.button("Prepare AnnData (.h5ad)"):
+ tmp = make_tmp(".h5ad")
+ with st.spinner("Writing…"):
+ adata.write_h5ad(tmp)
+ with open(tmp, "rb") as f:
+ st.download_button(
+ "Download .h5ad",
+ f.read(),
+ file_name=f"scptr_{st.session_state.dataset_name}.h5ad",
+ mime="application/octet-stream",
+ )
+
+ with col2:
+ if gamma is not None:
+ st.markdown("**Gamma matrix**")
+ st.markdown(
+ ''
+ 'Cells × genes CSV of degradation rates γ.
',
+ unsafe_allow_html=True,
+ )
+ if st.button("Prepare γ matrix (.csv)"):
+ with st.spinner("Building CSV…"):
+ gamma_df = pd.DataFrame(
+ gamma,
+ index=adata.obs_names,
+ columns=adata.var_names,
+ )
+ csv_bytes = gamma_df.to_csv().encode()
+ st.download_button(
+ "Download gamma.csv",
+ csv_bytes,
+ file_name=f"gamma_{st.session_state.dataset_name}.csv",
+ mime="text/csv",
+ )
+
+ with col3:
+ st.markdown("**Cell metadata**")
+ st.markdown(
+ ''
+ 'PT state assignments per cell (CSV).
',
+ unsafe_allow_html=True,
+ )
+ obs_cols = [c for c in ["pt_state"] if c in adata.obs.columns]
+ if obs_cols:
+ obs_csv = adata.obs[obs_cols].copy().to_csv().encode()
+ st.download_button(
+ "Download metadata.csv",
+ obs_csv,
+ file_name=f"metadata_{st.session_state.dataset_name}.csv",
+ mime="text/csv",
+ )
+ else:
+ st.markdown(
+ 'Run Discover PT States first to populate cell metadata.
',
+ unsafe_allow_html=True,
+ )
+
+ st.markdown('
', unsafe_allow_html=True)
+ col_d1, col_d2, col_d3 = st.columns(3)
+
+ with col_d1:
+ if beta is not None:
+ st.markdown("**Gene splicing rates (β)**")
+ st.markdown(
+ ''
+ 'Per-gene β from phase portrait quantile regression.
',
+ unsafe_allow_html=True,
+ )
+ beta_df = pd.DataFrame({"gene": beta.index, "beta": beta.values})
+ st.download_button(
+ "Download beta.csv",
+ beta_df.to_csv(index=False).encode(),
+ file_name=f"beta_{st.session_state.dataset_name}.csv",
+ mime="text/csv",
+ )
+
+ with col_d2:
+ if "tf_score" in adata.var.columns:
+ st.markdown("**Variance decomposition**")
+ st.markdown(
+ ''
+ 'TF and PTF score per gene (0–1).
',
+ unsafe_allow_html=True,
+ )
+ vd_df = pd.DataFrame({
+ "gene": adata.var_names,
+ "tf_score": adata.var["tf_score"].values,
+ "ptf_score": adata.var["ptf_score"].values,
+ })
+ st.download_button(
+ "Download variance_decomp.csv",
+ vd_df.to_csv(index=False).encode(),
+ file_name=f"variance_decomp_{st.session_state.dataset_name}.csv",
+ mime="text/csv",
+ )
+
+ with col_d3:
+ st.markdown("**Analysis parameters**")
+ st.markdown(
+ ''
+ 'Reproducibility: parameters logged by scPTR.
',
+ unsafe_allow_html=True,
+ )
+ params_log = adata.uns.get("scptr", {})
+ if params_log:
+ st.download_button(
+ "Download parameters.json",
+ json.dumps(params_log, indent=2, default=str).encode(),
+ file_name=f"parameters_{st.session_state.dataset_name}.json",
+ mime="application/json",
+ )
+ else:
+ st.markdown(
+ 'No logged parameters yet — run the full pipeline to populate.
',
+ unsafe_allow_html=True,
+ )
+
+ if len(net) > 0:
+ st.markdown('
', unsafe_allow_html=True)
+ st.markdown("**RBP–target network**")
+ st.markdown(
+ ''
+ 'Columns: regulator, target, weight. Positive weight = destabilizing; negative = stabilizing.
',
+ unsafe_allow_html=True,
+ )
+ net_csv = net.to_csv(index=False).encode()
+ st.download_button(
+ "Download network.csv",
+ net_csv,
+ file_name=f"network_{st.session_state.dataset_name}.csv",
+ mime="text/csv",
+ )
+
+ st.markdown('
', unsafe_allow_html=True)
+ if st.button("← Start Over"):
+ clean_tmps()
+ for k, v in {
+ "step": 1,
+ "adata": None,
+ "dataset_name": None,
+ "preprocessed": False,
+ "estimated": False,
+ "states_done": False,
+ "velocity_done": False,
+ "network_done": False,
+ }.items():
+ st.session_state[k] = v
+ nav("analysis"); st.rerun()
+
+
+# ══════════════════════════════════════════════════════════════════════════════
+# DOCUMENTATION PAGE
+# ══════════════════════════════════════════════════════════════════════════════
+elif page == "docs":
+ st.markdown('Documentation
', unsafe_allow_html=True)
+ st.markdown(
+ 'Method details, parameter reference, and interpretation guide.
',
+ unsafe_allow_html=True,
+ )
+
+ dtab1, dtab2, dtab3, dtab4, dtab5, dtab6 = st.tabs(["METHOD", "PARAMETERS", "INTERPRETATION", "QUICK START", "TROUBLESHOOTING", "CITATION"])
+
+ # ── Method ────────────────────────────────────────────────────────────────
+ with dtab1:
+ st.markdown(
+ ''
+ '
The kinetic model
'
+ '
'
+ 'scPTR is based on the kinetic model of RNA metabolism where each gene g has a '
+ 'transcription rate α, splicing rate β, and degradation rate γ. At steady state, '
+ 'the rates satisfy:'
+ '
'
+ '
'
+ 'du/dt = α − β · u = 0 → u* = α/β\n'
+ 'ds/dt = β · u − γ · s = 0 → s* = α/γ\n\n'
+ 'Therefore: γ_ig = β_g · u_ig / s_ig'
+ '
'
+ '
'
+ 'This means γ is directly estimable from observed spliced and unspliced counts, '
+ 'given an estimate of β. Critically, γ can vary per cell because of '
+ 'post-transcriptional regulatory programs (miRNA-mediated repression, RBP binding, '
+ 'codon usage, etc.).'
+ '
'
+ '
'
+ '
Beta estimation
'
+ '
'
+ 'The splicing rate βg is gene-specific and estimated from the phase portrait '
+ '(u vs. s plot) using quantile regression on the upper boundary of the u/s ratio. '
+ 'This approach captures the slope of the kinetic upper boundary, which reflects the '
+ 'maximum u/s ratio observed across cells — corresponding to minimal degradation.'
+ '
'
+ '
'
+ 'Concretely, β̂g = quantile(uig / sig, q=0.95) '
+ 'clipped at the 99th percentile of positive values.'
+ '
'
+ '
'
+ '
Post-transcriptional state discovery
'
+ '
'
+ 'To identify cell populations with distinct degradation programs, scPTR:'
+ '
'
+ '
'
+ '- Computes PCA on the γ matrix (cells × genes)
'
+ '- Builds a kNN graph in γ-PCA space
'
+ '- Runs Leiden community detection
'
+ '- Embeds in 2D using UMAP for visualization
'
+ '
'
+ '
'
+ 'These clusters can differ from expression-based clusters — a cell may be '
+ 'transcriptionally similar to its neighbors but have a distinct degradation program '
+ '("expression-invisible" state).'
+ '
'
+ '
'
+ 'Zero-permutation control: scPTR validates that PT states are not artifactual '
+ 'by permuting γ values randomly across cells and recomputing clusters. The adjusted '
+ 'Rand index (ARI) between real and permuted PT states should be near 0.'
+ '
'
+ '
'
+ '
RBP–target network inference
'
+ '
'
+ 'For each target gene, scPTR regresses its γ values across cells on the '
+ 'smoothed expression of regulator genes (putative RBPs) using elastic net regression:'
+ '
'
+ '
γ_target ~ Σ_r coef_r · expr_r + ε
'
+ '
'
+ 'Non-zero coefficients indicate regulatory relationships. Positive coefficients imply '
+ 'the regulator promotes degradation (destabilizing); negative implies protection '
+ '(stabilizing).'
+ '
'
+ '
'
+ f'| {name} | '
+ f'{type_} | '
+ f'{default} | '
+ f'{desc} | '
+ f'
'
+ )
+
+ tables = [
+ ("pp.filter_genes", [
+ ("min_unspliced_counts", "int", "10", "Minimum total unspliced count across all cells."),
+ ("min_unspliced_cells", "int", "5", "Minimum cells with nonzero unspliced expression."),
+ ("min_spliced_counts", "int", "0", "Minimum total spliced count (rarely changed)."),
+ ]),
+ ("pp.neighbors", [
+ ("n_neighbors", "int", "30", "Number of nearest neighbors for the cell graph."),
+ ("n_pcs", "int", "30", "PCA components used to build the neighbor graph."),
+ ]),
+ ("pp.smooth_layers", [
+ ("bandwidth", "float | None", "None", "Gaussian kernel bandwidth. None = adaptive (median kNN distance)."),
+ ]),
+ ("tl.estimate_beta", [
+ ("quantile", "float", "0.95", "Upper quantile of u/s ratio used as the kinetic boundary."),
+ ]),
+ ("tl.estimate_gamma", [
+ ("clip_quantile", "float", "0.99", "Per-gene clipping quantile to remove extreme γ values."),
+ ("min_spliced", "float", "0.01", "Minimum smoothed spliced (Ms) for reliable γ; below this γ = 0."),
+ ("mode", "str", "'steady_state'", "'steady_state' or 'dynamic' (uses ds/dt from RNA velocity)."),
+ ]),
+ ("tl.pt_states", [
+ ("resolution", "float", "0.5", "Leiden resolution. Higher → more, smaller clusters."),
+ ("n_pcs", "int", "30", "PCA components computed from the γ matrix."),
+ ("n_neighbors", "int", "30", "kNN neighbors in γ-PCA space."),
+ ("random_state", "int", "0", "Random seed for PCA, UMAP, and Leiden."),
+ ]),
+ ("tl.pt_velocity", [
+ ("use_graph", "str", "'gamma'", "'gamma' = γ-space kNN graph; 'expression' = expression kNN graph."),
+ ]),
+ ("tl.infer_network", [
+ ("regulators", "list | None", "None", "Regulator gene names. None = all genes used as regulators."),
+ ("targets", "list | None", "None", "Target gene names. None = all genes used as targets."),
+ ("method", "str", "'elasticnet'", "Regression method. Currently only 'elasticnet'."),
+ ("alpha", "float", "0.5", "Elastic net mixing: 0 = ridge, 1 = lasso, 0.5 = elastic net."),
+ ("n_top", "int", "50", "Maximum edges to retain per target gene."),
+ ]),
+ ]
+
+ for fn_name, params in tables:
+ rows = "".join(param_row(*p) for p in params)
+ st.markdown(
+ f''
+ f'
{fn_name}
'
+ f'
'
+ f'| Parameter | Type | Default | Description |
|---|
'
+ f'{rows}'
+ f'
'
+ f'
'
+ '
Interpreting γ values
'
+ '
'
+ 'γ (gamma) represents the mRNA degradation rate — higher γ means faster '
+ 'turnover. Key relationships:'
+ '
'
+ '
'
+ '| γ value | Meaning |
|---|
'
+ ''
+ '| γ = 0 | Insufficient spliced counts; rate not estimable |
'
+ '| γ → small (e.g., 0.001) | Slow degradation; stable mRNA |
'
+ '| γ → large (e.g., 0.5+) | Rapid degradation; unstable mRNA |
'
+ '| γ varies across cells | Post-transcriptional regulation; likely RBP or miRNA activity |
'
+ '
'
+ '
'
+ '
Interpreting PT states
'
+ '
'
+ 'A PT state is a cluster of cells with similar γ profiles. Biologically, this means:'
+ '
'
+ '
'
+ '- Same PT state, same expression cluster: transcriptional and post-transcriptional programs are aligned
'
+ '- Different PT states within one expression cluster: expression-invisible state — cells look identical transcriptionally but differ in RNA stability
'
+ '- Same PT state, different expression clusters: convergent post-transcriptional programs across distinct cell types
'
+ '
'
+ '
'
+ 'Use the silhouette score to assess separation: higher in γ-space than '
+ 'expression-space indicates a genuine post-transcriptional signature.'
+ '
'
+ '
'
+ '
Interpreting PT velocity
'
+ '
'
+ 'PT velocity captures the direction and magnitude of change in γ across the '
+ 'γ-space neighborhood graph. Unlike RNA velocity (which reflects nascent → mature RNA '
+ 'flow), PT velocity is orthogonal — it reflects where in γ-space a cell is headed.'
+ '
'
+ '
'
+ '- Arrow direction: predicted future γ profile of the cell
'
+ '- Arrow length: magnitude of degradation-rate change (longer = faster transition)
'
+ '- Coherent arrows in a region suggest a shared post-transcriptional program being gained or lost
'
+ '- Divergent arrows suggest a decision point where cells adopt different degradation programs
'
+ '
'
+ '
'
+ 'PT velocity precedes expression changes for 54–78% of transition genes '
+ '(pancreas p < 10⁻⁵⁷, dentate gyrus p = 9.9×10⁻¹³), making it a leading '
+ 'indicator of cell-fate decisions.'
+ '
'
+ '
'
+ '
Interpreting network edges
'
+ '
'
+ 'RNA-binding proteins (RBPs) are post-transcriptional regulators that bind mRNA to control '
+ 'stability, splicing, and translation. scPTR infers RBP→target edges where RBP expression '
+ 'predicts γ of the target, using library-size-corrected elastic net regression.'
+ '
'
+ '
'
+ 'Each edge has a weight (regression coefficient):'
+ '
'
+ '
'
+ '- Positive weight: RBP expression correlates with higher γ → '
+ 'the RBP destabilizes the target mRNA
'
+ '- Negative weight: RBP expression correlates with lower γ → '
+ 'the RBP stabilizes the target mRNA
'
+ '- |weight| magnitude: filter by |weight| > 0.05 to retain high-confidence edges
'
+ '- Hub regulators (many edges) are likely master regulators '
+ '— validated hubs include HNRNPA1, YBX1, ELAVL1/HuR, RBFOX1
'
+ '
'
+ '
'
+ 'To validate edges, cross-reference with CLIP-seq databases (e.g., ENCODE eCLIP, '
+ 'ATtRACT) or miRNA target databases (TargetScan) for experimental support.'
+ '
'
+ '
'
+ '
Python quick start
'
+ '
'
+ 'import scptr\n\n'
+ '# Load data (must have spliced + unspliced layers)\n'
+ 'adata = scptr.read_h5ad("your_data.h5ad")\n\n'
+ '# Preprocessing\n'
+ 'scptr.pp.filter_genes(adata, min_unspliced_counts=10, min_unspliced_cells=5)\n'
+ 'scptr.pp.normalize_layers(adata)\n'
+ 'scptr.pp.neighbors(adata, n_neighbors=30, n_pcs=30)\n'
+ 'scptr.pp.smooth_layers(adata) # Gaussian kernel smoothing\n\n'
+ '# Rate estimation\n'
+ 'scptr.tl.estimate_beta(adata, quantile=0.95)\n'
+ 'scptr.tl.estimate_gamma(adata, clip_quantile=0.99, min_spliced=0.01)\n'
+ 'scptr.tl.variance_decomposition(adata)\n\n'
+ '# PT state discovery\n'
+ 'scptr.tl.pt_states(adata, resolution=0.5, n_pcs=20, n_neighbors=15)\n\n'
+ '# Optional: PT velocity\n'
+ 'scptr.tl.pt_velocity(adata, use_graph="gamma")\n\n'
+ '# Optional: RBP–target network\n'
+ 'net = scptr.tl.infer_network(adata, alpha=0.5, n_top=50)\n'
+ '# Results in adata.uns["pt_network"]\n\n'
+ '# Visualization\n'
+ 'scptr.pl.pt_umap(adata) # γ-space UMAP\n'
+ 'scptr.pl.gamma_heatmap(adata, groupby="pt_state")\n'
+ 'scptr.pl.network_graph(adata, n_edges=50)'
+ '
'
+ '
'
+ '
Installation
'
+ '
'
+ 'pip install . # core package\n'
+ 'pip install ".[datasets]" # built-in pancreas / dentate gyrus\n'
+ 'pip install ".[deep]" # DeepPTR (PyTorch)\n'
+ 'pip install ".[dev]" # pytest for testing'
+ '
'
+ '
Requirements
'
+ '
'
+ 'Python ≥ 3.9, anndata ≥ 0.8, scanpy ≥ 1.9, numpy ≥ 1.21, scipy ≥ 1.7, '
+ 'scikit-learn ≥ 1.0, numba ≥ 0.55, matplotlib ≥ 3.5'
+ '
'
+ '
'
+ '
Data preparation
'
+ '
'
+ 'scPTR requires raw, un-normalized spliced and unspliced counts '
+ 'in an AnnData .h5ad file. Tools for generating these:'
+ '
'
+ '
'
+ '| Tool | Notes |
|---|
'
+ ''
+ '| STARsolo | Produces spliced/unspliced with --soloFeatures SJ Gene Velocyto |
'
+ '| Alevin-fry | Use splici index; outputs spliced + unspliced per cell |
'
+ '| velocyto | Run on BAM files post-alignment; outputs loom → convert to h5ad |
'
+ '| kallisto|bustools | Use kb-python with --workflow lamanno |
'
+ '
'
+ '
Input data requirements
'
+ '
'
+ 'scPTR requires raw (un-normalized) counts in both layers. '
+ 'Do not pre-normalize with Seurat, Scanpy, or other pipelines — '
+ 'scPTR performs its own library-size normalization internally. '
+ 'STARsolo and Alevin-fry output is already raw; velocyto loom files are also raw.'
+ '
'
+ '
Verify your data has required layers
'
+ '
'
+ 'import anndata as ad\n'
+ 'adata = ad.read_h5ad("your_data.h5ad")\n'
+ 'print(list(adata.layers.keys())) # must include "spliced" and "unspliced"\n'
+ 'print(adata.shape) # (n_cells, n_genes)\n'
+ '# Check counts are raw (integers)\n'
+ 'import numpy as np\n'
+ 'print(np.allclose(adata.layers["spliced"] % 1, 0)) # True = raw counts'
+ '
'
+ '
--soloFeatures Velocyto), velocyto, or Alevin-fry with a splici index."),
+ ("All γ values are zero",
+ "Gamma layer exists but all values are 0",
+ "This happens when Ms (smoothed spliced) is below the min_spliced threshold everywhere. "
+ "Try reducing Min smoothed spliced (Ms) to 0.001 in step 3, or check that normalization ran correctly."),
+ ("Very few genes after filtering",
+ "n_vars drops to < 100 after preprocessing",
+ "Lower Min total unspliced counts or Min cells with nonzero unspliced in step 2. "
+ "Some datasets have sparse unspliced counts — try 5 and 3 respectively."),
+ ("PT states = 1 (all cells in one cluster)",
+ "Only 1 Leiden cluster found",
+ "Increase the Leiden resolution (try 1.0–2.0). Also check that the γ matrix has variance — "
+ "if most values are 0, the clustering will be uninformative."),
+ ("Network inference is slow",
+ "Elastic net taking > 10 minutes",
+ "Check 'Restrict regulators to known RBPs' to reduce the feature matrix from all genes "
+ "to ~200 curated RBPs. Also reduce Top edges per target to 20–30."),
+ ("Dataset download fails",
+ "pooch.HTTPError or FileNotFoundError for example datasets",
+ "Ensure pip install \"scptr[datasets]\" is installed and you have an internet connection. "
+ "The pancreas dataset is ~30 MB and dentate gyrus ~25 MB."),
+ ("Memory error on large dataset",
+ "MemoryError or kernel crash",
+ "The γ matrix (cells × genes) can be large. Try filtering more aggressively in step 2 "
+ "(higher min counts). For >20,000 cells, consider subsetting to highly variable genes first."),
+ ("Phase portrait shows no clear line",
+ "β estimates are noisy / R² is very low",
+ "This is normal for some genes. Raise the Phase portrait quantile to 0.97–0.99 "
+ "to better capture the kinetic upper boundary. Genes with very low counts will always have noisy portraits."),
+ ]
+ for title, symptom, fix in issues:
+ st.markdown(
+ f''
+ f'
{title}
'
+ f'
Symptom
'
+ f'
{symptom}
'
+ f'
Fix
'
+ f'
{fix}
'
+ f'
'
+ '
Citing scPTR
'
+ '
'
+ 'If you use scPTR in your research, please cite:'
+ '
'
+ '
'
+ 'Bryan Cheng*, Austin Jin*\n'
+ 'scPTR: Decomposing Post-Transcriptional Regulation at Single-Cell Resolution\n'
+ '(2026)'
+ '
'
+ '
BibTeX
'
+ '
'
+ '@article{cheng2026scptr,\n'
+ ' title = {scPTR: Decomposing Post-Transcriptional Regulation\n'
+ ' at Single-Cell Resolution},\n'
+ ' author = {Cheng, Bryan and Jin, Austin},\n'
+ ' year = {2026},\n'
+ '}'
+ '
'
+ '
'
+ '
Dependencies to cite
'
+ '
'
+ 'scPTR builds on these foundational tools — please also cite them as appropriate:'
+ '
'
+ '
'
+ '| Tool | Use in scPTR | Reference |
|---|
'
+ ''
+ '| scanpy | PCA, neighbors, UMAP, Leiden clustering | '
+ 'Wolf et al., Genome Biology 2018 |
'
+ '| anndata | Core data structure | '
+ 'Virshup et al., Nat Methods 2024 |
'
+ '| scikit-learn | Elastic net regression (network inference) | '
+ 'Pedregosa et al., JMLR 2011 |
'
+ '| scVelo | Steady-state kinetic model inspiration | '
+ 'Bergen et al., Nat Biotechnol 2020 |
'
+ '
'
+ '