plannotate/RL/ori_breakdown.json

{
  "sequences_with_any_ori_hit": 3797,
  "distinct_ori_descriptions": 18,
  "top_ori_descriptions": {
    "high-copy-number ColE1/pMB1/pBR322/pUC origin of replication": 4353,
    "f1 bacteriophage origin of replication; arrow indicates direction of (+) strand synthesis": 2859,
    "Plasmids containing the medium-copy-number p15A origin of replication can be propagated in E. coli cells that contain a second plasmid with the ColE1 origin.": 515,
    "incP origin of replication": 16,
    "yeast 2\u03bc plasmid origin of replication": 15,
    "Plasmids containing the RSF 1030 origin of replication can be propagated in E. coli cells that contain additional plasmids with compatible origins.": 12,
    "internally truncated variant of the Epstein-Barr virus oriP replication origin (Tanaka et al., 1999)": 11,
    "S. cerevisiae autonomously replicating sequence ARS1": 5,
    "origin of replication for the Pseudomonas plasmid pVS1 (Heeb et al., 2000)": 5,
    "Epstein-Barr virus oriP replication origin (Yates et al., 2000)": 4,
    "low-copy replication origin that requires the Rep101 protein": 4,
    "M13 bacteriophage origin of replication; arrow indicates direction of (+) strand synthesis": 4,
    "incP origin of transfer": 3,
    "temperature-sensitive version of the RepA protein needed for replication with the pSC101 origin (Armstrong et al., 1984); rep101 encoding an A56V mutation": 3,
    "SV40 origin of replication": 3,
    "the original enhanced GFP (Yang et al., 1996) mammalian codon-optimized": 2,
    "TERM_ADE02 - Experimental evidence at protein level: Swiss-Prot protein existence level 1. Protein covalently bound to the viral DNA that acts as a primer for viral genomic replication by DNA strand displacement. Assembles on the viral origin of replication in an initiation complex with viral polymerase, DBP, host NFIA and host POU2F1/OCT1. During initiation, the polymerase covalently couples the first dCTP with Ser- 580 of pTP. The terminal protein stimulates the template activity over 20 fold compared to protein-free templates. Neo-synthesized viral genomes are linked to two preterminal proteins, one for each 5' end. These new genomes are encapsidated in the nucleus, and during capsid maturation by viral protease, preterminal protein is first cleaved into intermediary (iTP), then into mature TP. May play a role in host nuclear matrix localization of genomic DNA. From Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2).": 2,
    "origin of replication for the bacterial F plasmid": 1
  },
  "sequences_with_exactly_one_unique_ori_family": {
    "high-copy-number ColE1/pMB1/pBR322/pUC origin of replication": 802,
    "Plasmids containing the medium-copy-number p15A origin of replication can be propagated in E. coli cells that contain a second plasmid with the ColE1 origin.": 2,
    "Plasmids containing the RSF 1030 origin of replication can be propagated in E. coli cells that contain additional plasmids with compatible origins.": 2,
    "f1 bacteriophage origin of replication; arrow indicates direction of (+) strand synthesis": 2,
    "yeast 2\u03bc plasmid origin of replication": 1,
    "internally truncated variant of the Epstein-Barr virus oriP replication origin (Tanaka et al., 1999)": 1
  }
}