# This source code is licensed under the license found in the # LICENSE file in the root directory of this source tree. # -------------------------------------------------------- # References: # DeepHiC: https://github.com/omegahh/DeepHiC # -------------------------------------------------------- import torch import torch.nn as nn def swish(x): return x * torch.sigmoid(x) # DeepHiC Residual Block class residualBlock(nn.Module): def __init__(self, channels, k=3, s=1): super(residualBlock, self).__init__() self.conv1 = nn.Conv2d(channels, channels, k, stride=s, padding=1) self.bn1 = nn.BatchNorm2d(channels) # a swish layer here self.conv2 = nn.Conv2d(channels, channels, k, stride=s, padding=1) self.bn2 = nn.BatchNorm2d(channels) def forward(self, x): residual = swish(self.bn1(self.conv1(x))) residual = self.bn2(self.conv2(residual)) return x + residual # DeepHiC Generator class Generator(nn.Module): def __init__(self, num_channels=64, resblock_num=5): super(Generator, self).__init__() self.conv1 = nn.Conv2d(1, num_channels, kernel_size=9, stride=1, padding=4) # have a swish here in forward resblocks = [residualBlock(num_channels) for _ in range(resblock_num)] self.resblocks = nn.Sequential(*resblocks) self.conv2 = nn.Conv2d(num_channels, num_channels, kernel_size=3, stride=1, padding=1) self.bn2 = nn.BatchNorm2d(num_channels) # have a swish here in forward self.conv3 = nn.Conv2d(num_channels, 1, kernel_size=9, stride=1, padding=4) def forward(self, x): emb = swish(self.conv1(x)) x = self.resblocks(emb) x = swish(self.bn2(self.conv2(x))) x = self.conv3(x + emb) return (torch.tanh(x) + 1) / 2 # DeepHiC Discriminator class Discriminator(nn.Module): def __init__(self, in_channel=3): super(Discriminator, self).__init__() self.conv1 = nn.Conv2d(in_channel, 64, 3, stride=1, padding=1) self.conv2 = nn.Conv2d(64, 64, 3, stride=2, padding=1) self.bn2 = nn.BatchNorm2d(64) self.conv3 = nn.Conv2d(64, 128, 3, stride=1, padding=1) self.bn3 = nn.BatchNorm2d(128) self.conv4 = nn.Conv2d(128, 128, 3, stride=2, padding=1) self.bn4 = nn.BatchNorm2d(128) self.conv5 = nn.Conv2d(128, 256, 3, stride=1, padding=1) self.bn5 = nn.BatchNorm2d(256) self.conv6 = nn.Conv2d(256, 256, 3, stride=2, padding=1) self.bn6 = nn.BatchNorm2d(256) # Replaced original paper FC layers with FCN self.conv7 = nn.Conv2d(256, 1, 1, stride=1, padding=0) self.avgpool = nn.AdaptiveAvgPool2d(1) def forward(self, x): batch_size = x.size(0) x = swish(self.conv1(x)) x = swish(self.bn2(self.conv2(x))) x = swish(self.bn3(self.conv3(x))) x = swish(self.bn4(self.conv4(x))) x = swish(self.bn5(self.conv5(x))) x = swish(self.bn6(self.conv6(x))) x = self.conv7(x) x = self.avgpool(x) return torch.sigmoid(x.view(batch_size))