trial_id stringlengths 11 11 | label int64 0 2 | profile_text stringlengths 191 1.2k | taxonomy stringlengths 246 17k |
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NCT00000106 | 0 | The patient is a 58-year-old woman with longstanding seropositive rheumatoid arthritis and marked morning stiffness lasting about 90 minutes, reporting difficulty with dressing, gripping utensils, and walking more than a block. She has failed prior treatment with methotrexate and sulfasalazine due to persistent synovit... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "seropositive rheumatoid arthritis", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "morning stiffne... |
NCT00000106 | 1 | 52-year-old woman with seropositive rheumatoid arthritis by ACR criteria, with symmetric MCP/PIP synovitis, erosive changes on hand films, and longstanding morning stiffness lasting 90 minutes. She is functionally class III with marked difficulty climbing stairs and opening jars, despite prior inadequate response to hy... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "seropositive rheumatoid arthritis", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "rheu... |
NCT00000106 | 2 | The patient is a 58-year-old woman with seropositive rheumatoid arthritis meeting ACR criteria, with longstanding symmetric inflammatory polyarthritis involving the hands, wrists, and knees and functional class III limitation. She has had inadequate response to multiple DMARDs, including methotrexate and sulfasalazine,... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "seropositive rheumatoid arthritis", "code_expr": [{"unit": "1", "value": 1.0, "operator": "==", "subject_name": "ser... |
NCT00000125 | 0 | A 67-year-old man with hypertension and hyperlipidemia was referred after a routine optometry visit noted borderline elevated pressures. On repeat exam, best-corrected visual acuity was 20/25 OD and 20/20 OS, with intraocular pressures of 18 mm Hg in the right eye and 19 mm Hg in the left by applanation. Slit lamp and ... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hyperlipidemia", "code_expr": null}, {"i... |
NCT00000125 | 1 | A 58-year-old man presents for glaucoma evaluation after elevated pressures were noted on routine optometry screening. Best-corrected visual acuity is 20/25 OD and 20/20 OS, with applanation IOP measuring 28 mm Hg in the right eye and 24 mm Hg in the left on repeat testing. Gonioscopy shows open angles without narrow c... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "glaucoma", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "glaucoma"}]}, {"id": "T3", "typ... |
NCT00000125 | 2 | A 58-year-old man with no prior ocular procedures presents for routine glaucoma evaluation after elevated screening pressures were noted at his optometry visit. Best-corrected visual acuity is 20/20 OD and 20/25 OS, with applanation pressures of 27 mm Hg in the right eye and 23 mm Hg in the left; gonioscopy shows open ... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Procedure", "text": "prior ocular procedures", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "glaucoma", "code_expr": null}... |
NCT00000153 | 0 | A 62-year-old man with type 2 diabetes mellitus presents for routine follow-up and reports no visual complaints. He has a history of hypertension and hyperlipidemia, but no known diabetic eye disease. Recent ophthalmology evaluation noted clear lenses and normal fundus photographs without retinal neovascularization or ... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "type 2 diabetes mellitus", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": ... |
NCT00000153 | 1 | 58-year-old man with a long history of diabetes mellitus presents with proliferative diabetic retinopathy. Exam shows neovascularization of the optic disc in the right eye measuring approximately DRS Standard Photograph 10A equivalent, with additional fine new vessels extending onto the retinal surface near the disc. O... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "diabetes mellitus", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "diabetes mellitus"}]},... |
NCT00000153 | 2 | A 56-year-old man with a history of diabetes mellitus presents for retinal evaluation and is found to have neovascularization of the optic nerve head in the right eye, with new vessels extending onto the disc consistent with at least DRS Standard Photograph 10A severity. The ocular media are clear enough to permit fund... | {"entities": [{"id": "T1", "type": "Person", "text": "56-year-old man", "code_expr": [{"unit": "1", "value": 56.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "diabetes mellitus", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "neovascularization of the optic ner... |
NCT00000427 | 0 | A 42-year-old man presents for follow-up of chronic low back pain after a remote lumbar strain, with no history of fragility fracture. He has well-controlled hypertension and seasonal allergies, takes lisinopril and a daily antihistamine, and denies steroid use, anticonvulsants, or other medications affecting bone heal... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic low back pain", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "remote lumbar strain", "code_ex... |
NCT00000427 | 1 | 58-year-old man referred for evaluation of low bone mass after a screening DXA showed lumbar spine T-score of -2.7 and femoral neck T-score of -2.4, with no prior fragility fractures. His labs are otherwise unremarkable, including creatinine 0.9 mg/dL, AST/ALT within normal range, total testosterone 540 ng/dL, 25-OH vi... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "low bone mass", "code_expr": [{"unit": "1", "value": 1.0, "operator": "==", "subject_name": "low bone mass"}]}, {"id":... |
NCT00000427 | 2 | 58-year-old man with progressive low back discomfort and a DXA scan showing lumbar spine T-score of -2.6 with femoral neck T-score of -2.3, consistent with marked osteopenia/osteoporosis for age. Serum creatinine 0.9 mg/dL, AST/ALT within normal limits, total testosterone 540 ng/dL, 25-OH vitamin D 34 ng/mL, and intact... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "progressive low back discomfort", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "lumbar spine T-scor... |
NCT00000599 | 0 | 58-year-old woman with a 2-year history of rheumatoid arthritis and chronic kidney disease stage 3, seen for follow-up of poorly controlled hypertension and type 2 diabetes. She is a lifelong nonsmoker and denies any history of coronary artery disease, cardiac surgery, or angina. Recent labs showed fasting total choles... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "rheumatoid arthritis", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "chronic kidney disease stage 3... |
NCT00000599 | 1 | A 52-year-old man with a documented history of progressive coronary atherosclerosis confirmed on prior angiography presents for study screening. He underwent coronary artery bypass grafting 6 months ago and remains clinically stable since surgery. He is a lifelong non-smoker and his fasting total cholesterol at entry i... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old man", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "progressive coronary atherosclerosis", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "prior angiograph... |
NCT00000599 | 2 | A 52-year-old man who is a lifelong nonsmoker presents for study screening. He has documented progressive atherosclerosis on prior coronary angiography and underwent coronary artery bypass grafting 8 months ago. Recent fasting laboratory testing shows a total cholesterol of 192 mg/dL at entry. He is otherwise clinicall... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "progressive atherosclerosis", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "coronary angiography", "code_expr": null}, {"id": "T4", "type": "Procedure", "text": "corona... |
NCT00001165 | 0 | A 62-year-old man with long-standing type 2 diabetes and hypertension presents for evaluation of chronic epigastric pain, intermittent diarrhea, and recurrent peptic ulcer disease despite high-dose proton pump inhibitor therapy. Upper endoscopy showed multiple distal duodenal ulcers, and prior biopsy from a pancreatic ... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": [{"unit": "year", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "type 2 diabetes", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": null},... |
NCT00001165 | 1 | 58-year-old man with biopsy-confirmed pancreatic gastrinoma and Zollinger-Ellison syndrome, followed for refractory peptic ulcer disease and chronic diarrhea despite high-dose acid suppression. Recent contrast CT and octreotide imaging show liver metastases with interval enlargement of the primary lesion over the last ... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "year", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "biopsy-confirmed pancreatic gastrinoma", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name":... |
NCT00001165 | 2 | Middle-aged man with a long-standing Zollinger-Ellison syndrome has biopsy-confirmed pancreatic gastrinoma from prior EUS-guided sampling. Cross-sectional imaging over the last several months shows enlarging hepatic lesions and a locally invasive mass abutting the duodenum, consistent with metastatic and invasive disea... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "Zollinger-Ellison syndrome", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "pancreatic gastrinoma", "code_expr": null}, {"id": "T4", "type": "Procedure", "text": "EUS-gu... |
NCT00001237 | 0 | 67-year-old man with a history of chronic hepatitis C and hypertension presents with progressive weight loss, night sweats, and generalized fatigue. CT imaging shows a bulky mediastinal mass and multiple enlarged cervical and retroperitoneal lymph nodes, and biopsy demonstrates lymphoblastic lymphoma. He has not receiv... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "years", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic hepatitis C", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": n... |
NCT00001237 | 1 | A 12-year-old boy was diagnosed with Burkitt lymphoma presenting as a small, localized abdominal mass with involvement of adjacent segmental lymph nodes. The mass was completely resected at surgery, and his serum LDH is 240 U/L. He has no evidence of testicular involvement, no prior chemotherapy or radiation, and no hi... | {"entities": [{"id": "T1", "type": "Person", "text": "12-year-old boy", "code_expr": [{"unit": "a", "value": 12.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "Burkitt lymphoma", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "Burkitt lymphoma"}]}, {... |
NCT00001237 | 2 | A 12-year-old boy presents with newly diagnosed Burkitt lymphoma involving a localized abdominal mass with adjacent segmental lymph nodes. The mass was completely resected at surgery, and his serum LDH is 240 U/L, below 1.5 times the upper limit of normal. He has no testicular involvement, no prior chemotherapy or radi... | {"entities": [{"id": "T1", "type": "Person", "text": "12-year-old boy", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "Burkitt lymphoma", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "localized abdominal mass", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "adjacent segm... |
NCT00001339 | 0 | 62-year-old woman with biopsy-confirmed recurrent adrenocortical carcinoma involving the left adrenal bed and two small hepatic lesions, felt to be potentially resectable after induction chemotherapy. She has measurable disease on CT, Karnofsky performance status 80%, and an estimated life expectancy greater than 3 mon... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old woman", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "biopsy-confirmed recurrent adrenocortical carcinoma", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": ... |
NCT00001339 | 1 | A 52-year-old woman with biopsy-proven recurrent adrenocortical carcinoma presents with a 4.2 cm measurable left retroperitoneal mass and a single small hepatic metastasis, both felt to be potentially resectable after response to chemotherapy. She completed her last cycle of chemotherapy 6 weeks ago and previously tole... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "recurrent adrenocortical carcinoma", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "4.2 cm", "code_expr": [{"unit": "cm", "value": 4.2, "operator": "==", "subject_na... |
NCT00001339 | 2 | The patient is a 52-year-old woman with biopsy-confirmed recurrent adrenocortical carcinoma with a limited number of measurable pulmonary nodules and a small regional nodal recurrence, felt to be potentially resectable after induction therapy. She completed prior mitotane and tolerated 3 g/day for over a week; her last... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "recurrent adrenocortical carcinoma", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "pulmonary nodules", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "... |
NCT00001347 | 0 | A 67-year-old man presents with progressive bilateral sensorineural hearing loss that began in early adulthood and has been stable with hearing aids. He also reports night blindness since his teens with gradually worsening peripheral vision, and ophthalmologic evaluation confirms retinitis pigmentosa. There is no histo... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "progressive bilateral sensorineural hearing loss", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject... |
NCT00001347 | 1 | The patient is a 28-year-old woman with a longstanding history of bilateral sensorineural hearing loss noted in early childhood and progressive night blindness with peripheral visual field constriction consistent with retinitis pigmentosa. Ophthalmologic and audiologic evaluations support Usher syndrome type 2, with no... | {"entities": [{"id": "T1", "type": "Person", "text": "28-year-old woman", "code_expr": [{"unit": "a", "value": 28.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "bilateral sensorineural hearing loss", "code_expr": null}, {"id": "T3", "type": "Temporal", "text": "early childhood... |
NCT00001347 | 2 | The patient is a 28-year-old woman with longstanding bilateral sensorineural hearing loss diagnosed in early childhood and progressive retinitis pigmentosa with night blindness and peripheral visual field constriction. Audiology and ophthalmologic evaluation are consistent with Usher syndrome type 2, with no history su... | {"entities": [{"id": "T1", "type": "Person", "text": "28-year-old woman", "code_expr": [{"unit": "a", "value": 28.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "bilateral sensorineural hearing loss", "code_expr": null}, {"id": "T3", "type": "Temporal", "text": "early c... |
NCT00001371 | 0 | 32-year-old woman presents for evaluation of chronic plaque psoriasis involving the trunk and extremities, with estimated body surface area involvement of about 8%. She is otherwise healthy, ambulatory, and has no history of systemic illness, immunodeficiency, or significant cardiac disease. She reports no prior use of... | {"entities": [{"id": "T1", "type": "Person", "text": "32-year-old woman", "code_expr": [{"unit": "year", "value": 32.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic plaque psoriasis", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "plaque pso... |
NCT00001446 | 0 | A 68-year-old man with a remote history of type 2 diabetes and hypertension presents for routine follow-up; he has no known cancer history, denies weight loss, bone pain, urinary obstruction, or pelvic symptoms. Recent PSA was 2.1 ng/mL, and prior imaging for back discomfort showed only degenerative lumbar spondylosis ... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "type 2 diabetes", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": null}, {"... |
NCT00001446 | 1 | A 71-year-old man with biopsy-proven prostatic adenocarcinoma, originally diagnosed on transrectal needle biopsy, now with castration-resistant progression despite ongoing leuprolide and prior bicalutamide withdrawal. Over the last 5 weeks he has had three serial PSA rises from 18.4 to 29.7 ng/mL, with repeat imaging s... | {"entities": [{"id": "T1", "type": "Person", "text": "71-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "prostatic adenocarcinoma", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "castration-resistant progression", "code_expr": null}, {"id": "T4", "type": "Drug", "text": "le... |
NCT00001446 | 2 | Mr. J.S. is a 68-year-old man with biopsy-proven prostatic adenocarcinoma from the Clinical Center pathology review, now with castration-resistant progression despite ongoing leuprolide and prior bicalutamide withdrawal. Over the past month he has had three serial PSA rises (12.4, 16.8, and 21.5 ng/mL) with testosteron... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "prostatic adenocarcinoma", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "prostatic adeno... |
NCT00001527 | 0 | 68-year-old woman presents for routine follow-up with a history of type 2 diabetes, chronic kidney disease, and prior myocardial infarction. Current medications include metformin, lisinopril, atorvastatin, and aspirin. Recent labs show total cholesterol of 178 mg/dL and blood pressure well controlled at 128/76 mmHg. Sh... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old woman", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "type 2 diabetes", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "type 2 diabetes"}]}, {... |
NCT00001527 | 1 | 52-year-old woman presents for screening enrollment. She is otherwise healthy, takes no prescription or over-the-counter medications, and has no significant past medical history. Blood pressure is 118/72 mmHg and fasting total cholesterol is 178 mg/dL. She is not using any contraceptive medications. | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Measurement", "text": "Blood pressure", "code_expr": [{"unit": "mm[Hg]", "value": 118.0, "operator": "==", "subject_name": "systolic bloo... |
NCT00001527 | 2 | Patient is a 52-year-old woman with no significant past medical history and is not taking any medications, including contraceptives. She is in good health on review of systems and physical exam, with no known chronic conditions. Fasting serum cholesterol is 178 mg/dL. She meets the study criteria for a normal volunteer... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": null}, {"id": "T2", "type": "Value", "text": "52-year-old", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T3", "type": "Condition", "text": "no significant past medical history", "code... |
NCT00001532 | 0 | A 64-year-old woman with longstanding exertional dyspnea, intermittent wheeze, and chronic cough productive of scant sputum presents for pulmonary follow-up. She has a 35 pack-year smoking history and quit 5 years ago; prior workup showed severe obstructive physiology on spirometry with reduced DLCO and hyperinflation,... | {"entities": [{"id": "T1", "type": "Person", "text": "64-year-old woman", "code_expr": [{"unit": "a", "value": 64.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "exertional dyspnea", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "intermittent wheeze", "code_expr... |
NCT00001532 | 1 | 57-year-old man with longstanding tobacco exposure, currently smoking about 1 pack per day for the past 30 years, followed for progressive dyspnea on exertion, chronic cough, and intermittent wheeze. Chest radiograph shows hyperinflation with bibasilar scarring, and spirometry demonstrates moderate obstructive physiolo... | {"entities": [{"id": "T1", "type": "Person", "text": "57-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "progressive dyspnea on exertion", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "chronic cough", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "intermitt... |
NCT00001532 | 2 | 56-year-old man with known alpha-1 antitrypsin deficiency, phenotype PiZZ, followed for progressive emphysema and chronic exertional dyspnea. He has a 28 pack-year smoking history, quit 5 years ago, and now reports daily cough, reduced exercise tolerance, and intermittent wheeze; chest radiograph shows hyperinflation w... | {"entities": [{"id": "T1", "type": "Person", "text": "56-year-old man", "code_expr": [{"unit": "a", "value": 56.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "alpha-1 antitrypsin deficiency", "code_expr": [{"unit": "a", "value": 1.0, "operator": "==", "subject_name": "alpha-1 ... |
NCT00001549 | 0 | 79-year-old man with a 4-year history of gradually progressive bradykinesia, masked facies, and intermittent resting tremor, now requiring a walker for short distances. Family reports increasing forgetfulness, slowed processing, and occasional visual misperceptions over the past year; he also has longstanding constipat... | {"entities": [{"id": "T1", "type": "Person", "text": "79-year-old man", "code_expr": [{"unit": "a", "value": 79.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "bradykinesia", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "bradykinesia"}]}, {"id": "T... |
NCT00001549 | 1 | A 74-year-old man with a 6-year history of progressive bradykinesia, shuffling gait, and intermittent resting tremor was referred for evaluation of worsening motor fluctuations and mild short-term memory decline. Neurologic workup has been most consistent with idiopathic Parkinsonian syndrome, though his family notes i... | {"entities": [{"id": "T1", "type": "Person", "text": "74-year-old man", "code_expr": [{"unit": "a", "value": 74.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "idiopathic Parkinsonian syndrome", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "progressive bradykin... |
NCT00001549 | 2 | 67-year-old man with a 4-year history of gradually progressive bradykinesia, resting tremor, and gait slowing, now with intermittent freezing and mild hypophonia. Neurology notes describe an identifiable parkinsonian syndrome, with prior trial of carbidopa/levodopa providing partial benefit; he also has well-controlled... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "parkinsonian syndrome", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "parkinsonian syndr... |
NCT00001615 | 0 | 68-year-old man with a history of hypertension, hyperlipidemia, and remote tobacco use presents for routine eye follow-up after noticing gradual difficulty reading the newspaper and recognizing faces. He has bilateral age-related macular changes with soft drusen noted on exam, but the right eye retains 20/25 acuity and... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hyperlipidemia", "code_expr": null}, {"id": "T4", "type": "Observation", "text": "remote tobacco use", "cod... |
NCT00001615 | 1 | 67-year-old man with bilateral age-related macular degeneration, drusen noted in both maculae on exam, and a longstanding neovascular scar in the right eye from subfoveal CNVM with counting-fingers vision there (20/400+ equivalent). The left eye is the study eye; best-corrected acuity is 20/100, with subtle grayish sub... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "bilateral age-related macular degeneration", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name"... |
NCT00001615 | 2 | 78-year-old woman with age-related macular degeneration followed for several years, with confluent soft drusen in both maculae and a new subfoveal choroidal neovascular membrane in the right eye. Best-corrected visual acuity is 20/125 OD and 20/400 OS, with the left eye reduced from exudative CNVM-related scarring; she... | {"entities": [{"id": "T1", "type": "Person", "text": "78-year-old woman", "code_expr": [{"unit": "a", "value": 78.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "age-related macular degeneration", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "age-r... |
NCT00001629 | 0 | A 46-year-old man presents with a 2-day history of fever, productive cough, and pleuritic chest pain. He has no history of cardiac disease and denies exertional symptoms, syncope, or edema. Chest imaging is being pursued for suspected community-acquired pneumonia rather than any cardiovascular indication. He is not tak... | {"entities": [{"id": "T1", "type": "Person", "text": "46-year-old man", "code_expr": [{"unit": "a", "value": 46.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "fever", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "productive cough", "code_expr": null}, {"id": "... |
NCT00001629 | 1 | The patient is a 62-year-old woman with chronic exertional chest pain referred for diagnostic cardiac catheterization. She has a history of hypertension and mild heart failure with preserved renal function, and her prior workup suggests nonobstructive coronary disease. She is postmenopausal and has been on chronic estr... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old woman", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic exertional chest pain", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "diagnostic cardiac ca... |
NCT00001629 | 2 | A 62-year-old woman with chronic exertional chest pain is being evaluated for diagnostic cardiac catheterization. She has a history of hypertension and hyperlipidemia, and prior noninvasive testing suggested possible ischemia, though prior angiography showed nonobstructive coronary arteries. She is on chronic estrogen ... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old woman", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic exertional chest pain", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "chest pa... |
NCT00001643 | 0 | 58-year-old woman with a history of progressive gait instability and resting tremor, but no clear bradykinesia or levodopa responsiveness. Family history is notable for a father with Alzheimer disease and a brother with hypertension, with no known Parkinson's disease in the family. She has no cognitive impairment and r... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "progressive gait instability", "code_expr": [{"unit": "1", "value": 1.0, "operator": "==", "subject_name": "progress... |
NCT00001643 | 1 | A 67-year-old man with a long-standing diagnosis of Parkinson’s disease presents with resting tremor, bradykinesia, and clear improvement on carbidopa-levodopa. His family history is notable for Parkinson’s disease in his father, an older sister, and one paternal uncle across three generations, and he is the only affec... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "Parkinson\u2019s disease", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "resting tremor", "code_expr"... |
NCT00001643 | 2 | 68-year-old man with a long-standing diagnosis of Parkinson’s disease, confirmed by resting tremor, bradykinesia, and a clear clinical response to levodopa. Family history is notable for three affected relatives across three generations, including his father and two siblings, consistent with familial PD; he is the only... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "Parkinson\u2019s disease", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "resting tremor", "code_expr"... |
NCT00001693 | 0 | A 46-year-old woman presents for routine follow-up after prior left hemicolectomy for stage I colon adenocarcinoma. She reports intermittent NSAID use for arthritis several times weekly over the past few months and is currently taking daily aspirin. Genetic testing previously showed no Lynch syndrome mutation, and ther... | {"entities": [{"id": "T1", "type": "Person", "text": "46-year-old woman", "code_expr": [{"unit": "year", "value": 46.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Procedure", "text": "left hemicolectomy", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "stage I colon adenocarcinoma"... |
NCT00001693 | 1 | A 46-year-old woman with Lynch syndrome confirmed by a pathogenic MLH1 mutation and a personal history of endometrial carcinoma presents for trial screening. She has an intact colon with no prior colectomy, no chemotherapy or pelvic radiation in the past, and denies any recent NSAID, aspirin, or steroid use. She is not... | {"entities": [{"id": "T1", "type": "Person", "text": "46-year-old woman", "code_expr": [{"unit": "year", "value": 46.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "Lynch syndrome", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "pathogenic MLH1 mutation", "cod... |
NCT00001693 | 2 | A 42-year-old woman with a known pathogenic MSH2 mutation and a personal history of microsatellite instability–high colon adenocarcinoma, meeting Amsterdam criteria for HNPCC, presents for study screening. She is status post right hemicolectomy 2 years ago with operative records documenting greater than 50% of colorect... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "pathogenic MSH2 mutation", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "microsatellite instability... |
NCT00001724 | 0 | 58-year-old male presents for routine follow-up with a history of hypertension, type 2 diabetes mellitus, and chronic low back pain. He reports taking lisinopril, metformin, and ibuprofen as needed for joint aches. No current dental complaints, and he denies any planned oral surgery or need for wisdom tooth extraction.... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old male", "code_expr": [{"unit": "year", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "type 2 diabetes mellitus", "code_exp... |
NCT00001724 | 1 | 18-year-old female presents for extraction of two impacted mandibular third molars with partial bony impaction and is agreeable to local anesthesia with IV midazolam only. She plans to return for removal of the remaining maxillary third molars at a second visit. No history of NSAID allergy, aspirin-induced asthma, or o... | {"entities": [{"id": "T1", "type": "Person", "text": "18-year-old female", "code_expr": [{"unit": "a", "value": 18.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Procedure", "text": "extraction of two impacted mandibular third molars with partial bony impaction", "code_expr": null}, {"id": "T3", "... |
NCT00001724 | 2 | 19-year-old female presents for removal of two impacted mandibular third molars with partial bony impaction. She agrees to undergo oral surgery under local anesthesia with intravenous midazolam only and is willing to return for staged extraction of the remaining maxillary third molars at a second appointment. She has n... | {"entities": [{"id": "T1", "type": "Person", "text": "19-year-old female", "code_expr": [{"unit": "year", "value": 19.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Procedure", "text": "removal of two impacted mandibular third molars", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": ... |
NCT00002620 | 0 | 67-year-old woman with a history of stage III colon adenocarcinoma treated years ago, now presenting with progressive headaches and gait instability after a recent ischemic stroke. Brain MRI showed a left temporal ring-enhancing lesion, and stereotactic biopsy confirmed glioblastoma with marked necrosis; she underwent ... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old woman", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "stage III colon adenocarcinoma", "code_expr": [{"unit": "1", "value": 3.0, "operator": "==", "subject_name": "stage"... |
NCT00002620 | 1 | A 42-year-old man with a recent diagnosis of anaplastic astrocytoma, confirmed on pathology after near-total resection performed 18 days ago, now seen for consideration of protocol therapy. He is neurologically stable with an ECOG performance status of 1, ambulates independently, and reports only mild intermittent head... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "anaplastic astrocytoma", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "near-total resection", "code_e... |
NCT00002620 | 2 | A 42-year-old woman with a recently diagnosed, histologically confirmed anaplastic astrocytoma underwent near-total surgical resection 18 days ago, with postoperative MRI showing only minimal residual nonenhancing disease. She is ambulatory and independent with an ECOG performance status of 1, denies focal neurologic d... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "anaplastic astrocytoma", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "near-total surgical resectio... |
NCT00002706 | 0 | A 67-year-old woman presents with progressive shortness of breath and unintentional weight loss, and imaging shows a right upper lobe lung mass with mediastinal adenopathy concerning for metastatic non-small cell lung cancer. She has a history of hypertension and chronic kidney disease stage 3, but no gynecologic malig... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old woman", "code_expr": [{"unit": "year", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "progressive shortness of breath", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "sho... |
NCT00002706 | 1 | The patient is a 58-year-old woman with newly diagnosed FIGO stage I, grade 2 endometrioid adenocarcinoma of the uterus. She is an appropriate surgical candidate with ECOG/GOG performance status 1, and there is no clinical or chest x-ray evidence of extrauterine spread or gross endocervical involvement. Laboratory stud... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "endometrioid adenocarcinoma of the uterus", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "newly diagnosed", "code_expr": null}, {"id": "T4", "type": "Qualifier", "tex... |
NCT00002706 | 2 | The patient is a 58-year-old woman with newly diagnosed FIGO stage IA, grade 2 endometrioid adenocarcinoma of the endometrium. She is a good surgical candidate and has no contraindication to laparoscopy; chest imaging shows no evidence of metastatic disease beyond the uterine corpus and no gross endocervical involvemen... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "newly diagnosed FIGO stage IA, grade 2 endometrioid adenocarcinoma of the endometrium", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "FIGO stage IA", "code_expr": nul... |
NCT00002746 | 0 | A 68-year-old man with a history of chronic myelodysplastic syndrome, previously diagnosed as refractory anemia with ringed sideroblasts, is being followed for persistent macrocytic anemia and thrombocytopenia. He remains ambulatory with a Karnofsky score of 80 and has no symptoms of heart failure, coronary disease, dy... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic myelodysplastic syndrome", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "refractory anemia wi... |
NCT00002746 | 1 | A 68-year-old man with a bone marrow biopsy confirming refractory anemia with ringed sideroblasts is being evaluated for treatment. He is ambulatory with a Karnofsky performance status of 80%, and his platelet count is 65,000/µL. Laboratory studies show bilirubin 0.9 mg/dL, AST 42 U/L, and creatinine 1.1 mg/dL, with no... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "refractory anemia with ringed sideroblasts", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "bone marro... |
NCT00002746 | 2 | A 68-year-old man with histologically confirmed myelodysplastic syndrome, refractory anemia with ringed sideroblasts, presents for trial screening. He is fully ambulatory with a Karnofsky performance status of 80, and his platelet count is 78,000/µL. Laboratory studies show bilirubin 0.9 mg/dL, AST 42 U/L, and creatini... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "myelodysplastic syndrome", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "refractory anemia with ringe... |
NCT00002755 | 0 | A 52-year-old woman underwent lumpectomy and axillary dissection for stage II left breast cancer 3 weeks ago, with pathology showing 2 positive nodes and no residual disease in the axilla. She is ECOG 0, eating well, and has no significant past medical history. Recent labs show mild anemia and slightly elevated creatin... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": [{"unit": "year", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "stage II left breast cancer", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "lumpectomy", "code_e... |
NCT00002755 | 1 | 48-year-old woman with a history of stage IIIA breast cancer, status post definitive mastectomy and axillary dissection 5 weeks ago with 6 positive axillary nodes and no gross residual nodal disease on postoperative exam. She is ECOG 0, eating well, and has no history of HIV, second malignancy, or significant psychiatr... | {"entities": [{"id": "T1", "type": "Person", "text": "48-year-old woman", "code_expr": [{"unit": "a", "value": 48.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "stage IIIA breast cancer", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "definitive mastectomy", "c... |
NCT00002755 | 2 | The patient is a 54-year-old woman with histologically confirmed stage IIIA breast cancer status post definitive lumpectomy and axillary dissection 5 weeks ago, with 5 positive axillary nodes and no overt residual nodal disease on postoperative evaluation. She has ECOG performance status 0, is eating well with adequate... | {"entities": [{"id": "T1", "type": "Person", "text": "54-year-old woman", "code_expr": [{"unit": "a", "value": 54.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "histologically confirmed stage IIIA breast cancer", "code_expr": [{"unit": "", "value": 3.0, "operator": "==", "subj... |
NCT00002839 | 0 | A 62-year-old man with a biopsy-proven squamous cell carcinoma of the supraglottic larynx, staged clinically as T4N0M0, with imaging showing minimal thyroid cartilage invasion and bulging of the hyothyroid membrane. Panendoscopy, CT neck, and esophagoscopy confirm measurable disease, and the head and neck surgeon feels... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "squamous cell carcinoma of the supraglottic larynx", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "su... |
NCT00002839 | 1 | A 62-year-old man with biopsy-proven squamous cell carcinoma of the supraglottic larynx, staged T4N0M0, with imaging showing minimal thyroid cartilage invasion and bulging of the hyothyroid membrane. Panendoscopy, CT, MRI, and esophagoscopy confirm measurable disease, and he is deemed operable with a standard total lar... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "biopsy-proven squamous cell carcinoma of the supraglottic larynx", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "supraglottic larynx", "code_expr": null}, {"id": "T4", ... |
NCT00002839 | 2 | The patient is a 62-year-old man with histologically confirmed squamous cell carcinoma of the hypopharynx involving the pyriform sinus, stage III, with no massive thyroid cartilage destruction and no continuity between the primary lesion and any cervical node. Panendoscopy, esophagoscopy, and CT imaging show measurable... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "histologically confirmed squamous cell carcinoma of the hypopharynx", "code_expr": null}, {"id": "T3", "type": "Qualif... |
NCT00002999 | 0 | A 62-year-old man with a biopsy-confirmed squamous cell carcinoma arising in the nasopharynx presents with progressive nasal obstruction, intermittent epistaxis, and left-sided cervical adenopathy; PET/CT shows bulky locoregional disease consistent with stage IVB by imaging, but no distant metastatic lesions. Chest CT ... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "squamous cell carcinoma", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "arising in the nasopharynx", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "prog... |
NCT00002999 | 1 | A 52-year-old man with biopsy-confirmed non-keratinizing nasopharyngeal carcinoma, stage IVB by local staging but without radiographic evidence of distant spread, presents for trial screening. MRI and chest CT within the past month show no pulmonary, osseous, or hepatic lesions; alkaline phosphatase is normal and no ad... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "biopsy-confirmed non-keratinizing nasopharyngeal carcinoma", "code_expr": null}, {"id": "T3", "type": "Value", "text": "stage IVB", "code_expr": [{"unit": "1", "value": 4.0, "operator":... |
NCT00002999 | 2 | A 52-year-old man with biopsy-confirmed non-keratinizing nasopharyngeal carcinoma, AJCC stage IVA, presents for trial screening prior to any definitive treatment. Staging workup with CT chest and bone scan showed no evidence of pulmonary, osseous, or hepatic metastases; alkaline phosphatase and transaminases were withi... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old man", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "biopsy-confirmed non-keratinizing nasopharyngeal carcinoma", "code_expr": [{"unit": "", "value": 1.0, "operator": "=="... |
NCT00003067 | 0 | A 62-year-old woman with a history of poorly controlled type 2 diabetes and chronic obstructive pulmonary disease is seen for evaluation of progressive headaches and weight loss. Brain MRI is pending, but there is no evidence of a primary malignant glioma or any other intracranial mass, and she is not considered a cand... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old woman", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "type 2 diabetes", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "poorly controlled", "code_expr": nu... |
NCT00003067 | 1 | 58-year-old man with recurrent glioblastoma confirmed on MRI and prior pathology, now being evaluated for repeat neurosurgical debulking. He has a Karnofsky performance status of 70% and an estimated life expectancy of more than 4 months. Labs are within protocol limits with ANC 2,100/mm3, platelets 165,000/mm3, normal... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "recurrent glioblastoma", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "Karnofsky performance status... |
NCT00003067 | 2 | The patient is a 56-year-old man with recurrent glioblastoma confirmed on prior pathology and current MRI, now being evaluated for neurosurgical biopsy and possible tumor debulking. He has a Karnofsky performance status of 80% and an estimated life expectancy of more than 4 months. Laboratory studies show ANC 2,300/mm^... | {"entities": [{"id": "T1", "type": "Condition", "text": "recurrent glioblastoma", "code_expr": null}, {"id": "T2", "type": "Person", "text": "56-year-old man", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "Karnofsky performance status", "code_expr": [{"unit": "%", "value": 80.0, "operator": "==", "su... |
NCT00003095 | 0 | A 58-year-old woman with a history of hypertension and well-controlled type 2 diabetes was evaluated for a newly diagnosed invasive breast carcinoma and had been consented for SWOG-9623 screening prior to any systemic therapy. She ambulates independently and remains active with an ECOG performance status of 1, with no ... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "type 2 diabetes", "code_expr": null}, ... |
NCT00003095 | 1 | A 56-year-old woman with newly diagnosed breast carcinoma was evaluated for enrollment and was already registered on SWOG-9623, but had not yet initiated any protocol-directed therapy. She remained ambulatory with an ECOG performance status of 1 and reported only mild fatigue without weight loss or dyspnea. Baseline la... | {"entities": [{"id": "T1", "type": "Person", "text": "56-year-old woman", "code_expr": [{"unit": "a", "value": 56.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "breast carcinoma", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "already registered on SWOG-9623"... |
NCT00003095 | 2 | The patient is a 52-year-old woman with newly diagnosed breast carcinoma and was registered to SWOG-9623 today, with no systemic therapy started yet. She remains ambulatory and fully self-caring, with an ECOG performance status of 1 and an estimated life expectancy well beyond several months. Baseline labs are acceptab... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "breast carcinoma", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "no systemic therapy started yet"... |
NCT00003351 | 0 | A 67-year-old woman with a remote history of hormone-receptor–positive breast cancer treated years ago with lumpectomy, adjuvant AC-T chemotherapy, and radiation now has biopsy-proven metastatic adenocarcinoma involving the liver and multiple enlarged axillary nodes. Restaging CT shows interval enlargement of a right h... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old woman", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hormone-receptor\u2013positive breast cancer", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "lumpec... |
NCT00003351 | 1 | 52-year-old woman with biopsy-proven invasive ductal carcinoma of the left breast, ER/PR positive and HER2 negative, now with enlarging pulmonary nodules and a new lytic lesion in the iliac crest consistent with progressive metastatic disease. She has an ECOG performance status of 1, remains ambulatory, and imaging sho... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "biopsy-proven invasive ductal carcinoma of the left breast", "code_expr": null}, {"id": "T3", "type": "Qualifier", "... |
NCT00003351 | 2 | A 58-year-old woman with biopsy-proven invasive ductal adenocarcinoma of the breast, initially treated with lumpectomy, adjuvant AC-T, and breast irradiation, now has progressive metastatic disease involving the liver and left axillary nodes with a 2.4 cm measurable hepatic lesion on recent CT. She remains ECOG 1 with ... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "biopsy-proven invasive ductal adenocarcinoma of the breast", "code_expr": [{"unit": "", "value": 1.0, "operator": "=... |
NCT00003702 | 0 | 22-year-old woman with a recent hydatidiform mole treated by uterine curettage 6 weeks ago, now with persistent low-level beta-hCG that has failed to decline appropriately over three weekly measurements. Pathology confirmed low-risk gestational trophoblastic neoplasia consistent with persistent mole, with no evidence o... | {"entities": [{"id": "T1", "type": "Person", "text": "22-year-old woman", "code_expr": [{"unit": "a", "value": 22.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hydatidiform mole", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "uterine curettage", "code_expr": ... |
NCT00003702 | 1 | A 24-year-old woman with histologically confirmed persistent hydatidiform mole has had a plateaued beta-hCG with less than 10% decline over three weekly measurements following suction curettage performed 5 months ago. She has no evidence of metastatic disease, no prior chemotherapy, and her WHO score is 1 with GOG perf... | {"entities": [{"id": "T1", "type": "Person", "text": "24-year-old woman", "code_expr": [{"unit": "a", "value": 24.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "persistent hydatidiform mole", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "beta-hCG", "code_exp... |
NCT00003702 | 2 | 25-year-old woman with a histologically confirmed persistent hydatidiform mole after suction curettage 5 weeks ago, with beta-hCG levels showing less than 10% decline over three weekly measurements. She has no evidence of metastases, WHO risk score is 3, and performance status is GOG 1. CBC and chemistry are within tre... | {"entities": [{"id": "T1", "type": "Person", "text": "25-year-old woman", "code_expr": [{"unit": "a", "value": 25.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "persistent hydatidiform mole", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "suction curettage", "c... |
NCT00003811 | 0 | A 62-year-old man with a long history of heavy smoking presents with progressive weight loss, chronic cough, and hemoptysis. CT imaging shows a large left upper lobe lung mass with mediastinal lymphadenopathy and multiple liver lesions suspicious for metastatic non-small cell lung cancer. He previously received platinu... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": [{"unit": "year", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Observation", "text": "long history of heavy smoking", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "progressive weight... |
NCT00003811 | 1 | A 9-year-old boy was diagnosed with a biopsy-proven extracranial yolk sac tumor arising from the retroperitoneum, with measurable metastatic disease on imaging consistent with stage IV high-risk disease. He has not received any prior chemotherapy or radiotherapy, and the primary tumor was not previously resected. Labor... | {"entities": [{"id": "T1", "type": "Person", "text": "9-year-old boy", "code_expr": [{"unit": "year", "value": 9.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "extracranial yolk sac tumor", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "extracrania... |
NCT00003811 | 2 | A 6-year-old child was recently diagnosed by biopsy with a stage III extragonadal yolk sac tumor in the retroperitoneum, with measurable disease on CT imaging. The patient has had no prior chemotherapy or radiotherapy, and no systemic therapy before referral. Current labs show an ANC of 1,200/mm3, platelets of 180,000/... | {"entities": [{"id": "T1", "type": "Person", "text": "6-year-old child", "code_expr": [{"unit": "a", "value": 6.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "stage III extragonadal yolk sac tumor", "code_expr": [{"unit": "", "value": 3.0, "operator": "==", "subject_name": "st... |
NCT00004694 | 0 | 68-year-old man with a history of chronic tobacco use and longstanding hypertension presents for evaluation of recurrent chest pain and exertional dyspnea. He also has type 2 diabetes mellitus, coronary artery disease with prior stent placement, and mild chronic kidney disease. Medications include aspirin, metformin, l... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Observation", "text": "chronic tobacco use", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": nul... |
NCT00004694 | 1 | Patient is a 28-year-old woman with confirmed type I hereditary angioedema based on low C4, low C1 inhibitor antigenic level, and a positive family history. She reports recurrent episodic facial and extremity swelling with intermittent abdominal pain and had 2 attacks in the past 6 weeks. No history of acquired C1INH d... | {"entities": [{"id": "T1", "type": "Person", "text": "28-year-old woman", "code_expr": [{"unit": "a", "value": 28.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "type I hereditary angioedema", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "low C4", "code_expr"... |
NCT00004694 | 2 | Middle-aged man with confirmed hereditary angioedema, consistent with type I disease, with low C4 and low C1 esterase inhibitor antigenic level and a positive family history. He reports recurrent episodic facial and extremity swelling with intermittent abdominal pain, occurring 2-3 times over the past 6 weeks. He has n... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "hereditary angioedema", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "type I disease", "code_expr": null}, {"id": "T4", "type": "Measurement", "text": "C4", "code_expr"... |
NCT00004812 | 0 | A 42-year-old man with a history of chronic low back pain and hypertension presents for routine follow-up after a prior motor vehicle collision. He ambulates independently with a mildly antalgic gait but has no known spinal cord injury, and prior lumbar radiographs only showed mild degenerative disc disease without fra... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic low back pain", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": nul... |
NCT00004812 | 1 | A 34-year-old man with a remote T8 traumatic spinal cord contusion from a motorcycle crash 18 months ago, confirmed on prior MRI, presents for follow-up with persistent incomplete paraparesis and spastic gait. He is able to ambulate only short distances with a rolling walker; his fastest comfortable walking speed remai... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old man", "code_expr": [{"unit": "year", "value": 34.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "T8 traumatic spinal cord contusion", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "prior MRI", "co... |
NCT00004812 | 2 | A 34-year-old man with a remote traumatic T8 spinal cord contusion from a motorcycle crash 18 months ago, confirmed on prior MRI, presents for follow-up in rehab clinic. He has incomplete lower-extremity motor recovery with no ability to step independently and ambulates only short distances with a walker; his gait rema... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old man", "code_expr": [{"unit": "a", "value": 34.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "traumatic T8 spinal cord contusion", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "T8", "code_expr": ... |
NCT00005007 | 0 | A 67-year-old man with chronic exertional dyspnea and hypertension presents for evaluation of longstanding weight loss and fatigue. He has a history of chronic kidney disease attributed to hypertensive nephrosclerosis, with creatinine 2.6 mg/dL, and reports no nasal ulcers, hemoptysis, sinus symptoms, or skin purpura. ... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "1", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic exertional dyspnea", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr"... |
NCT00005007 | 1 | 52-year-old man with biopsy-proven granulomatous inflammation consistent with granulomatosis with polyangiitis, PR3-ANCA positive, with nasal crusting and purulent discharge, cavitary pulmonary nodules on chest imaging, and microscopic hematuria. BVAS is 11 within the past 2 weeks, and he weighs 78 kg; baseline labs sh... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "granulomatosis with polyangiitis", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "PR3-ANCA positive", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "na... |
NCT00005007 | 2 | 52-year-old woman with biopsy-confirmed granulomatous vasculitis consistent with Wegener's granulomatosis, weight 68 kg. She has chronic purulent nasal discharge, a cavitary lesion on chest imaging, and positive PR3-ANCA by ELISA, meeting more than two modified ACR criteria; BVAS was 7 at evaluation within the past 2 w... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": [{"unit": "year", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "granulomatous vasculitis consistent with Wegener's granulomatosis", "code_expr": [{"unit": "", "value": 0.0, "ope... |
NCT00005103 | 0 | 58-year-old man presents with recurrent burning pain and numbness in both feet, worse at night, along with chronic low back pain and a history of poorly controlled type 2 diabetes. He reports intermittent abdominal bloating and constipation but denies blistering skin lesions, photosensitivity, or dark urine. Laboratory... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "recurrent burning pain", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "numbness in both feet", "code_... |
NCT00005103 | 1 | A 54-year-old man with a long-standing diagnosis of sporadic porphyria cutanea tarda presents with photosensitive blistering and skin fragility on the dorsal hands and forearms. Prior workup showed elevated plasma porphyrins with a fluorescence maximum near 617 nm at neutral pH, increased urinary porphyrins predominant... | {"entities": [{"id": "T1", "type": "Person", "text": "54-year-old man", "code_expr": [{"unit": "a", "value": 54.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "sporadic porphyria cutanea tarda", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "porphyr... |
NCT00005103 | 2 | Middle-aged man with a well-documented history of sporadic porphyria cutanea tarda, presenting with chronic photosensitivity, skin fragility, and blistering on sun-exposed areas. Prior workup showed elevated plasma porphyrins with a fluorescence maximum near 617 nm at neutral pH, increased urinary porphyrins predominan... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged man", "code_expr": []}, {"id": "T2", "type": "Condition", "text": "porphyria cutanea tarda", "code_expr": []}, {"id": "T3", "type": "Condition", "text": "chronic photosensitivity", "code_expr": []}, {"id": "T4", "type": "Condition", "text": "skin fragili... |
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