trial_id stringlengths 11 11 | label int64 0 2 | profile_text stringlengths 342 1.2k | taxonomy stringlengths 467 9.23k |
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NCT00000292 | 1 | A 32-year-old woman with a 6-month history of smoked cocaine use, typically 3-4 times per week, reports at least one binge with roughly 0.5 g used over a single day. She is otherwise medically stable with normal CBC, electrolytes, liver panel, chest radiograph, and resting ECG, and her blood pressure today is 124/78 mm... | {"entities": [{"id": "T1", "type": "Person", "text": "32-year-old woman", "code_expr": [{"unit": "a", "value": 32.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Observation", "text": "smoked cocaine use", "code_expr": null}, {"id": "T3", "type": "Temporal", "text": "6-month history", "code_expr": ... |
NCT00000292 | 2 | A 33-year-old woman presents for research screening with a 6-month history of smoked crack cocaine use occurring several times weekly, including one binge episode estimated at about 0.5 g over a single day. She is otherwise medically well, with normal physical examination, CBC, CMP, liver enzymes, and chest radiograph;... | {"entities": [{"id": "T1", "type": "Person", "text": "33-year-old woman", "code_expr": [{"unit": "a", "value": 33.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Drug", "text": "smoked crack cocaine use", "code_expr": null}, {"id": "T3", "type": "Temporal", "text": "6-month history", "code_expr": n... |
NCT00000406 | 1 | An 74-year-old man presents for routine follow-up with chronic bilateral knee pain and osteoarthritic stiffness, otherwise ambulatory and able to follow commands appropriately. He has a history of total right knee arthroplasty performed several years ago with persistent mechanical discomfort on the operative side. Past... | {"entities": [{"id": "T1", "type": "Person", "text": "74-year-old man", "code_expr": [{"unit": "a", "value": 74.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic bilateral knee pain", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "osteoarthritic stiffness"... |
NCT00000406 | 2 | 78-year-old woman seen in clinic for chronic bilateral knee pain and mobility difficulty, with gradual decline over the past few years. She is alert, oriented, and able to follow multi-step commands during the exam; blood pressure today is 132/76 mmHg and she has no history of diabetes. Past surgical history is notable... | {"entities": [{"id": "T1", "type": "Person", "text": "78-year-old woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "chronic bilateral knee pain", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "mobility difficulty", "code_expr": null}, {"id": "T4", "type": "Temporal", "text": "past f... |
NCT00000413 | 1 | 9-year-old premenarchal girl presents for routine pediatric follow-up; growth and development are otherwise normal, and she has not yet started menses. Past history is notable for mild persistent asthma requiring daily inhaled corticosteroid therapy, with occasional albuterol use during viral illnesses. No other major ... | {"entities": [{"id": "T1", "type": "Person", "text": "9-year-old girl", "code_expr": [{"unit": "a", "value": 9.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Observation", "text": "premenarchal", "code_expr": null}, {"id": "T3", "type": "Visit", "text": "routine pediatric follow-up", "code_expr": ... |
NCT00000433 | 0 | The patient is a 42-year-old man with chronic low back pain and morning stiffness since his mid-20s, previously diagnosed with ankylosing spondylitis by rheumatology. He remains on naproxen 500 mg twice daily and low-dose prednisone 5 mg daily with partial symptom control; prior labs showed mildly elevated CRP and ESR,... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic low back pain", "code_expr": [{"unit": "1", "value": 1.0, "operator": "==", "subject_name": "low back pain"}]}... |
NCT00000433 | 1 | A 46-year-old man with a 12-year history of ankylosing spondylitis presents for routine follow-up with chronic inflammatory back pain, morning stiffness lasting over an hour, and reduced lumbar flexion; he remains on naproxen and low-dose prednisone 5 mg daily, with prior labs showing mild normocytic anemia and ESR/CRP... | {"entities": [{"id": "T1", "type": "Person", "text": "46-year-old man", "code_expr": [{"unit": "a", "value": 46.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "ankylosing spondylitis", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "chronic inflammatory back pain... |
NCT00000433 | 2 | A 42-year-old man with a 12-year history of radiographic ankylosing spondylitis presents for routine follow-up with chronic inflammatory back pain, morning stiffness, and limited lumbar flexion but remains ambulatory and active. He has been maintained on naproxen 500 mg twice daily and low-dose prednisone 5 mg daily wi... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "radiographic ankylosing spondylitis", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "chronic inflammat... |
NCT00000435 | 1 | A 42-year-old woman with seropositive rheumatoid arthritis diagnosed 3 years ago presents with ongoing inflammatory polyarthritis, with 10 swollen and 12 tender joints on exam despite stable hydroxychloroquine and low-dose prednisone 5 mg daily. She is able to provide informed consent and reports using oral contracepti... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "seropositive rheumatoid arthritis", "code_expr": null}, {"id": "T3", "type": "Temporal", "text": "3 years ago", "cod... |
NCT00000435 | 2 | A 42-year-old woman with seropositive rheumatoid arthritis diagnosed 3 years ago presents with persistent inflammatory polyarthritis despite hydroxychloroquine 200 mg BID and low-dose prednisone 5 mg daily. Exam shows 10 swollen and 14 tender joints involving the MCPs, PIPs, wrists, and both knees, consistent with acti... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "seropositive rheumatoid arthritis", "code_expr": null}, {"id": "T3", "type": "Temporal", "text": "3 years ago", "cod... |
NCT00000641 | 1 | 45-year-old man with advanced HIV disease by CDC criteria, previously on zidovudine and didanosine, now with recurrent fevers, weight loss, and Mycobacterium avium complex isolated from blood cultures. He is alert, oriented, and able to provide informed consent, and he states he is willing to comply with study visits a... | {"entities": [{"id": "T1", "type": "Person", "text": "45-year-old man", "code_expr": [{"unit": "a", "value": 45.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "advanced HIV disease by CDC criteria", "code_expr": null}, {"id": "T3", "type": "Drug", "text": "zidovudine", "code_ex... |
NCT00000641 | 2 | Middle-aged man with long-standing HIV infection meeting CDC AIDS criteria, currently on zidovudine and didanosine with stable adherence and no recent changes in antiretroviral regimen. Blood cultures drawn during a febrile workup grew Mycobacterium avium, and he is being evaluated for trial enrollment; he is alert, or... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged man", "code_expr": [{"unit": "years", "value": 45.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "HIV infection", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "CDC AIDS criteria", "code_e... |
NCT00000714 | 0 | Middle-aged man with advanced HIV infection and a recent admission for bilateral diffuse interstitial pneumonia treated empirically as PCP, now improved on oxygen by nasal cannula. He previously received trimethoprim-sulfamethoxazole but developed marked leukopenia and thrombocytopenia with rising creatinine, and later... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "advanced HIV infection", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "bilateral diffuse interstitial pneumonia", "code_expr": null}, {"id": "T4", "type": "Condition", ... |
NCT00000714 | 1 | Middle-aged man with longstanding HIV infection and a recent bronchoalveolar-lavage–confirmed Pneumocystis carinii pneumonia, admitted after failing to tolerate both TMP/SMX and pentamidine. During prior TMP/SMX therapy he developed a diffuse blistering morbilliform eruption with mucosal erosions and marked pruritus, a... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "HIV infection", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "Pneumocystis carinii pneumonia", "code_expr": null}, {"id": "T4", "type": "Procedure", "text": "bronchoalv... |
NCT00000714 | 2 | Middle-aged man with longstanding HIV infection and prior high-risk sexual exposure was admitted with worsening dyspnea, dry cough, and diffuse bilateral interstitial infiltrates consistent with Pneumocystis carinii pneumonia. He had already received a full course of TMP/SMX but developed marked leukopenia with two ANC... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "HIV infection", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "Pneumocystis carinii pneumonia", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "leukopenia... |
NCT00000802 | 0 | 52-year-old man with well-controlled hypertension and chronic hepatitis C presents for routine HIV follow-up; he is on antiretroviral therapy with an undetectable viral load and a most recent CD4 count of 148 cells/mm3. He previously stopped trimethoprim-sulfamethoxazole because of a diffuse pruritic rash and leukopeni... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old man", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "chronic hepatitis C", "code_expr": null}... |
NCT00000802 | 1 | A 42-year-old man with longstanding HIV infection and prior AIDS-defining immunosuppression presents for prophylaxis planning; his most recent CD4 count was 86 cells/mm3 (11%) and he previously had an episode of PCP last year. He developed a severe rash and transaminitis on trimethoprim-sulfamethoxazole, so it was perm... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "HIV infection", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "AIDS-defining immunosuppression", "code... |
NCT00000802 | 2 | 34-year-old man with longstanding HIV infection, currently on antiretroviral therapy with good adherence. His most recent CD4 count was 84 cells/mm3 (11%), with a prior episode of Pneumocystis jirovecii pneumonia several years ago; he completed treatment and has no current respiratory symptoms, hypoxemia, or radiograph... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old man", "code_expr": [{"unit": "a", "value": 34.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "longstanding HIV infection", "code_expr": null}, {"id": "T3", "type": "Drug", "text": "antiretroviral therapy", "code_... |
NCT00000998 | 0 | 62-year-old man with longstanding COPD, type 2 diabetes, and chronic kidney disease stage 3 presents with 4 days of fever, productive cough, and worsening dyspnea on exertion. Chest CT shows bilateral patchy ground-glass opacities with mild hypoxemia on room air, and bronchoscopy is pending for further workup; sputum b... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "COPD", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "type 2 diabetes", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "chronic kidney disease stage 3", "... |
NCT00000998 | 1 | A 42-year-old man with advanced HIV presents with 2 weeks of progressive dyspnea, dry cough, and exertional hypoxemia; chest imaging shows bilateral diffuse interstitial infiltrates, and bronchoalveolar lavage demonstrates more than one cluster of Pneumocystis organisms, consistent with untreated PCP for this episode. ... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "advanced HIV", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "progressive dyspnea", "code_expr": null}... |
NCT00000998 | 2 | HIV-positive man with progressive dyspnea, nonproductive cough, and exertional hypoxemia over the past 10 days; chest radiograph shows bilateral diffuse interstitial infiltrates with patchy ground-glass opacities. Induced sputum silver stain demonstrated multiple clusters of Pneumocystis organisms, and this current epi... | {"entities": [{"id": "T1", "type": "Condition", "text": "HIV-positive", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "progressive dyspnea", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "nonproductive cough", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "exertional hypo... |
NCT00001001 | 0 | 45-year-old man with longstanding HIV infection and chronic hepatitis B presents for routine follow-up; he stopped zidovudine 3 days ago and reports no antiretroviral use or other medications since then. He has no current fevers, cough, oral thrush, diarrhea, or other signs of opportunistic infection, and denies recent... | {"entities": [{"id": "T1", "type": "Person", "text": "45-year-old man", "code_expr": [{"unit": "a", "value": 45.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "HIV infection", "code_expr": [{"unit": "1", "value": 1.0, "operator": "==", "subject_name": "HIV infection"}]}, {"id":... |
NCT00001001 | 1 | 42-year-old man with HIV-associated Kaposi sarcoma presents for study screening; he is clinically stable and able to consent, with no evidence of active opportunistic infection and no recent cytotoxic therapy. He stopped zidovudine and all other medications 3 days ago, and his labs show platelets 168,000/mm3, ANC 2,400... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "HIV-associated Kaposi sarcoma", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "HI... |
NCT00001001 | 2 | 54-year-old man with HIV-associated Kaposi sarcoma presents for study enrollment after stopping zidovudine 5 days ago; he reports no antiretrovirals, antibiotics, or other medications taken in the last 72 hours and has not received any recent chemotherapy or radiation. He is clinically stable without fever, cough, oral... | {"entities": [{"id": "T1", "type": "Person", "text": "54-year-old man", "code_expr": [{"unit": "a", "value": 54.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "HIV-associated Kaposi sarcoma", "code_expr": null}, {"id": "T3", "type": "Drug", "text": "zidovudine", "code_expr": nu... |
NCT00001245 | 0 | 58-year-old man with type 2 diabetes, hypertension, and chronic low back pain presents for routine follow-up after an urgent care visit for cough and fatigue. CBC shows mild leukocytosis and eosinophils 4%, with no marked peripheral eosinophilia; stool studies were obtained for intermittent diarrhea but have been unrev... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "type 2 diabetes", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": null}, {"... |
NCT00001245 | 1 | A 42-year-old woman with a primary care physician in the community presented for evaluation of chronic pruritus, intermittent abdominal discomfort, and marked peripheral eosinophilia, with an absolute eosinophil count of 1,450/mm3 on repeat CBC and no alternative explanation identified after initial workup. She is able... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "chronic pruritus", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "intermittent abdominal discomfort", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "ma... |
NCT00001245 | 2 | A 42-year-old woman with a primary care physician in the community was referred for evaluation of persistent eosinophilia discovered on routine labs. CBC showed an absolute eosinophil count of 1,450/mm3 with otherwise unremarkable counts and no alternative explanation identified after review of medications, travel hist... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "persistent eosinophilia", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "absolute eosinophil count... |
NCT00001325 | 0 | 45-year-old man with a history of poorly controlled type 2 diabetes, hypertension, and prior ischemic stroke with residual right-sided weakness presents for follow-up of recurrent focal aware spells described as brief staring episodes with right hand automatisms, occurring several times per week. Brain MRI shows a chro... | {"entities": [{"id": "T1", "type": "Person", "text": "45-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "poorly controlled type 2 diabetes", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "prior is... |
NCT00001451 | 0 | 29-year-old woman seen for routine pre-op clearance prior to elective orthopedic surgery. She reports no history of transfusions, jaundice, liver disease, HIV infection, or prior anesthesia complications; screening labs are unremarkable with normal CBC and CMP, fasting glucose 89 mg/dL, and blood pressure 114/72 mmHg. ... | {"entities": [{"id": "T1", "type": "Person", "text": "29-year-old woman", "code_expr": [{"unit": "a", "value": 29.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Procedure", "text": "routine pre-op clearance", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "elective orthopedic surger... |
NCT00001451 | 1 | 35-year-old woman presenting for a routine pre-donation screening, generally healthy and within the acceptable age range for blood donation. She denies recent infections, high-risk travel, transfusions, or other deferral issues, and her exam is unremarkable with normal BMI and blood pressure. Past history is notable fo... | {"entities": [{"id": "T1", "type": "Person", "text": "35-year-old woman", "code_expr": [{"unit": "a", "value": 35.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Observation", "text": "routine pre-donation screening", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "generally health... |
NCT00001451 | 2 | A 34-year-old woman presents for routine pre-donation screening and is otherwise in good health. She has no history of viral hepatitis, HIV exposure risks, intravenous drug use, or high-risk sexual activity, and she denies prior transfusions or recent travel; she is not pregnant and has no plans for conception. Past me... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old woman", "code_expr": [{"unit": "a", "value": 34.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Visit", "text": "routine pre-donation screening", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "good health", "code_ex... |
NCT00001473 | 0 | A 67-year-old man with a long history of chronic sinus congestion and intermittent epistaxis was admitted for progressive dyspnea, hematuria, and worsening fatigue over several weeks. Urinalysis showed 3+ protein, numerous dysmorphic RBCs with casts, and creatinine had risen to 2.1 mg/dL from a baseline of 1.0; renal b... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic sinus congestion", "code_expr": [{"unit": "1", "value": 1.0, "operator": "==", "subject_name": "chronic sinus ... |
NCT00001564 | 0 | 27-year-old man with metastatic osteosarcoma of the femur, diagnosed in early adulthood and treated with multi-agent chemotherapy followed by limb-sparing surgery. He now has pulmonary and osseous progression after two prior salvage regimens, with ECOG performance status 1 and ongoing cancer-related pain controlled on ... | {"entities": [{"id": "T1", "type": "Person", "text": "27-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "metastatic osteosarcoma of the femur", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "of the femur", "code_expr": null}, {"id": "T4", "type": "Temporal", "text": "early ... |
NCT00001564 | 1 | 17-year-old male with recurrent Ewing sarcoma of the pelvis, originally diagnosed at age 15, with prior RT-PCR-confirmed EWSR1 fusion and measurable nodal/pelvic soft tissue disease on restaging. He completed induction chemotherapy and one salvage regimen, has been off cytoreductive therapy for 4 weeks, and has recover... | {"entities": [{"id": "T1", "type": "Person", "text": "17-year-old male", "code_expr": [{"unit": "a", "value": 17.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "recurrent Ewing sarcoma of the pelvis", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "Ewing sarcoma"... |
NCT00001564 | 2 | 18-year-old male with recurrent extraosseous Ewing sarcoma of the pelvis, biopsy-confirmed with an EWSR1 fusion by RT-PCR matching a protocol vaccine peptide. He previously completed frontline chemotherapy and one salvage regimen, with measurable pelvic and pulmonary disease on current imaging; no cytoreductive therapy... | {"entities": [{"id": "T1", "type": "Person", "text": "18-year-old male", "code_expr": [{"unit": "a", "value": 18.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "recurrent extraosseous Ewing sarcoma of the pelvis", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "b... |
NCT00001595 | 1 | A 29-year-old woman with a known sellar/suprasellar mass on prior MRI, followed for hyperprolactinemia and intermittent amenorrhea, is being evaluated for participation in a familial pituitary tumor linkage study. She is alert, understands the protocol, and has signed informed consent; she reports she can return for al... | {"entities": [{"id": "T1", "type": "Person", "text": "29-year-old woman", "code_expr": [{"unit": "a", "value": 29.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "sellar/suprasellar mass", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "hyperprolactinemi... |
NCT00001595 | 2 | A 19-year-old woman with a known sellar mass followed on serial MRI, most consistent with a pituitary adenoma, presents for research enrollment after being identified through her father’s history of multiple endocrine tumors. She reports willingness to participate in all study visits and her mother accompanies her to s... | {"entities": [{"id": "T1", "type": "Person", "text": "19-year-old woman", "code_expr": [{"unit": "a", "value": 19.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "sellar mass", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "pituitary adenoma", "code_expr": null},... |
NCT00001638 | 0 | 65-year-old man with a history of hypertension, hyperlipidemia, and exertional chest pressure evaluated by cardiology for possible coronary artery disease. He is alert and oriented, able to understand the study and provide informed consent, with stable vitals and a creatinine of 1.0 mg/dL. ECG shows normal sinus rhythm... | {"entities": [{"id": "T1", "type": "Person", "text": "65-year-old man", "code_expr": [{"unit": "a", "value": 65.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hyperlipidemia", "code_expr": null}, {"i... |
NCT00001638 | 1 | 62-year-old man with longstanding exertional chest pressure and known coronary artery disease referred for cardiac MRI evaluation. He is alert, oriented, and able to consent; vitals are stable with BP 138/76 and he ambulates independently. However, he has an implanted dual-chamber pacemaker for prior sick sinus syndrom... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "coronary artery disease", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "cardiac MRI evaluation", "code_expr": null}, {"id": "T4", "type": "Device", "text": "implanted d... |
NCT00001638 | 2 | 58-year-old man with a history of exertional chest pressure, hypertension, hyperlipidemia, and prior coronary stent placement is being evaluated for suspected ischemic heart disease. He is alert and oriented, able to understand the study and provide informed consent, and has no history of implanted pacemaker/ICD, cochl... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "exertional chest pressure", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr":... |
NCT00002137 | 1 | 62-year-old man with HIV-associated Kaposi sarcoma involving the lower extremities and oral mucosa, with estimated prognosis beyond 3 months. He completed liposomal doxorubicin 5 weeks ago and has recovered from prior mucositis and cytopenias; he denies any recent fevers, thrush, or other symptomatic opportunistic infe... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "HIV-associated Kaposi sarcoma", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "Kaposi sar... |
NCT00002137 | 2 | A 46-year-old man with longstanding HIV infection and biopsy-proven Kaposi sarcoma involving the lower extremities and oral mucosa presents for trial screening. He has completed liposomal doxorubicin 5 weeks ago with full recovery from prior mucositis and mild hand-foot soreness, and he is not receiving any other antic... | {"entities": [{"id": "T1", "type": "Person", "text": "46-year-old man", "code_expr": [{"unit": "a", "value": 46.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "HIV infection", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "Kaposi sarcoma", "code_expr": n... |
NCT00004728 | 1 | 67-year-old man with hypertension, diabetes, and hyperlipidemia presented 6 weeks ago with a transient right arm weakness and dysarthria lasting 20 minutes, and MRI showed a small left hemispheric ischemic infarct with near-complete recovery; his current mRS is 1 and he is independent with all ADLs. Conventional angiog... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "diabetes", "code_expr": null}, {"id": "T... |
NCT00004728 | 2 | 67-year-old man with hypertension, hyperlipidemia, and type 2 diabetes was admitted 6 weeks ago for a brief episode of slurred speech and right arm clumsiness lasting 20 minutes, with near-complete recovery by discharge. Cerebral angiography performed during that admission showed a 70% focal stenosis of the left M1 seg... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hyperlipidemia", "code_expr": null}, {"i... |
NCT00004731 | 1 | Mr. H is a 71-year-old man with a 6-year history of Parkinson disease, presenting with progressive bradykinesia, a pill-rolling resting tremor, and cogwheel rigidity, all clearly more pronounced on the right side. He also has masked facies, shuffling gait, and reduced arm swing, with symptoms partially responsive to ca... | {"entities": [{"id": "T1", "type": "Person", "text": "71-year-old man", "code_expr": [{"unit": "a", "value": 71.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "Parkinson disease", "code_expr": [{"unit": "1", "value": 1.0, "operator": "==", "subject_name": "Parkinson dis... |
NCT00004731 | 2 | The patient is a 68-year-old man with a 4-year history of progressively worsening parkinsonism, now with noticeable bradykinesia, a pill-rolling resting tremor, and cogwheel rigidity. Exam shows the motor findings are clearly more pronounced on the right, with reduced right arm swing, slowed finger taps, and mild stoop... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "parkinsonism", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "parkinsonism"}]}, {"id": "T... |
NCT00005657 | 0 | 52-year-old man with chronic fatigue and type 2 diabetes is followed for abnormal liver tests and a remote history of hepatitis B exposure. He has no known hepatitis C risk factors, and prior workup showed negative anti-HCV and undetectable HCV RNA. Liver ultrasound demonstrates mild hepatic steatosis without cirrhosis... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old man", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic fatigue", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "type 2 diabetes", "code_expr": null},... |
NCT00005657 | 1 | The patient is a 34-year-old man with chronic hepatitis C, genotype 1a, currently viremic with mildly elevated transaminases and no evidence of decompensated cirrhosis on prior biopsy. He previously completed a 12-week antiviral course with partial virologic response and remains under hepatology follow-up for ongoing d... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old man", "code_expr": [{"unit": "a", "value": 34.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic hepatitis C", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "genotype 1a", "code_expr": null},... |
NCT00005657 | 2 | The patient is a 46-year-old man with a remote history of hepatitis C exposure discovered on screening; anti-HCV remains positive, but repeat PCR has been undetectable on multiple occasions and prior abdominal imaging shows no evidence of chronic liver disease. He is clinically well without stigmata of portal hypertens... | {"entities": [{"id": "T1", "type": "Person", "text": "46-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "hepatitis C exposure", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "anti-HCV remains positive", "code_expr": null}, {"id": "T4", "type": "Measurement", "text": "PCR"... |
NCT00005774 | 0 | Term male newborn delivered via urgent C-section for placental abruption, birth weight 3280 g, now 2 days old, admitted to the NICU for poor feeding and transient tachypnea. Chest radiograph shows mild perihilar streaking without focal alveolar collapse, and the infant is breathing comfortably in room air with saturati... | {"entities": [{"id": "T1", "type": "Person", "text": "male newborn", "code_expr": null}, {"id": "T2", "type": "Procedure", "text": "urgent C-section", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "placental abruption", "code_expr": null}, {"id": "T4", "type": "Value", "text": "3280 g", "code_expr": [{"... |
NCT00005774 | 1 | Late preterm male infant, birth weight 1,780 g, now 6 hours of life, admitted for increasing work of breathing with grunting, nasal flaring, and diffuse reticulogranular opacities on chest radiograph consistent with surfactant deficiency RDS. He is currently on nasal CPAP at FiO2 0.30 to keep saturations in the high 80... | {"entities": [{"id": "T1", "type": "Person", "text": "Late preterm male infant", "code_expr": null}, {"id": "T2", "type": "Value", "text": "1,780 g", "code_expr": [{"unit": "g", "value": 1780.0, "operator": "==", "subject_name": "birth weight"}]}, {"id": "T3", "type": "Temporal", "text": "6 hours of life", "code_expr":... |
NCT00005774 | 2 | Male preterm neonate born at 31+2 weeks via spontaneous vaginal delivery, birth weight 1,780 g, now 7 hours old. He has increasing work of breathing with grunting and intercostal retractions; chest radiograph shows diffuse bilateral reticulogranular opacities with low lung volumes consistent with surfactant deficiency.... | {"entities": [{"id": "T1", "type": "Person", "text": "Male preterm neonate", "code_expr": null}, {"id": "T2", "type": "Value", "text": "31+2 weeks", "code_expr": [{"unit": "wk", "value": 31.2857142857, "operator": "==", "subject_name": "gestational age"}]}, {"id": "T3", "type": "Procedure", "text": "spontaneous vaginal... |
NCT00005937 | 1 | The patient is a 72-year-old man with myelodysplastic syndrome, refractory anemia with ring sideroblasts, diagnosed on marrow biopsy last year; repeat aspirate shows 6% blasts and no evidence of CMML or transformation to acute leukemia. He has been off hypomethylating therapy and other disease-directed treatment for 6 ... | {"entities": [{"id": "T1", "type": "Person", "text": "72-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "myelodysplastic syndrome", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "refractory anemia with ring sideroblasts", "code_expr": null}, {"id": "T4", "type": "Procedure"... |
NCT00005937 | 2 | The patient is a 72-year-old man with myelodysplastic syndrome, originally classified as refractory anemia with ring sideroblasts, now followed for chronic symptomatic anemia and intermittent thrombocytopenia. Bone marrow from last month showed 4% blasts without evidence of leukemic transformation, and his disease has ... | {"entities": [{"id": "T1", "type": "Person", "text": "72-year-old man", "code_expr": [{"unit": "a", "value": 72.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "myelodysplastic syndrome", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "refractory anemia with ring ... |
NCT00006334 | 0 | 14-year-old male with no history of delayed growth or pubertal concerns, seen in follow-up for intermittent asthma and seasonal allergies. Prior genetic workup for learning difficulties showed a normal 46,XY karyotype, and there is no evidence of sex chromosome mosaicism or other chromosomal abnormality. He is otherwis... | {"entities": [{"id": "T1", "type": "Person", "text": "14-year-old male", "code_expr": [{"unit": "year", "value": 14.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "intermittent asthma", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "seasonal allergies", "code_ex... |
NCT00006334 | 1 | 13-year-old phenotypic female with short stature and primary amenorrhea was referred after cytogenetic testing showed mosaic Turner syndrome, 45X/46XX, with 88% monosomy X cells on peripheral blood analysis. She has otherwise met study entry parameters for age and sex assignment, and her family is agreeable to research... | {"entities": [{"id": "T1", "type": "Person", "text": "13-year-old phenotypic female", "code_expr": [{"unit": "year", "value": 13.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "short stature", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "primary amenorrhea", "... |
NCT00006334 | 2 | 15-year-old phenotypic female with short stature and primary amenorrhea, followed by endocrinology for suspected Turner syndrome. Prior cytogenetic testing demonstrated a mosaic X-chromosomal abnormality with 45,X cells comprising 86% of lymphocytes and no evidence of autosomal aneuploidy or structural autosomal defect... | {"entities": [{"id": "T1", "type": "Person", "text": "15-year-old", "code_expr": [{"unit": "a", "value": 15.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Person", "text": "phenotypic female", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "short stature", "code_expr": null}... |
NCT00006401 | 1 | Male preterm neonate born at 28+4 weeks’ gestation via emergent C-section for maternal preeclampsia, birth weight 820 g, now 14 hours of life. He is intubated and mechanically ventilated for surfactant-deficient respiratory failure, with echocardiogram showing only a tiny PDA and no other structural cardiac defect or l... | {"entities": [{"id": "T1", "type": "Person", "text": "Male", "code_expr": null}, {"id": "T2", "type": "Person", "text": "preterm neonate", "code_expr": null}, {"id": "T3", "type": "Measurement", "text": "28+4 weeks\u2019 gestation", "code_expr": [{"unit": "wk", "value": 28.5714285714, "operator": "==", "subject_name": ... |
NCT00006401 | 2 | Male infant born at 27+4 weeks’ gestation via emergent C-section for severe maternal preeclampsia, birth weight 860 g. He is 14 hours old and remains intubated on conventional mechanical ventilation for surfactant-deficient respiratory failure with moderate oxygen requirement; chest radiograph shows diffuse reticulogra... | {"entities": [{"id": "T1", "type": "Person", "text": "Male infant", "code_expr": null}, {"id": "T2", "type": "Value", "text": "27+4 weeks", "code_expr": [{"unit": "wk", "value": 27.5714285714, "operator": "==", "subject_name": "gestational age"}]}, {"id": "T3", "type": "Procedure", "text": "emergent C-section", "code_e... |
NCT00006436 | 1 | A 42-year-old man with HIV on antiretroviral therapy was referred after an excisional lymph node biopsy at the NCI confirmed CD20-positive diffuse large B-cell lymphoma, stage III, with no prior cytotoxic chemotherapy exposure. He is ambulatory with an ECOG performance status of 1 and is able to consent; renal function... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "HIV", "code_expr": null}, {"id": "T3", "type": "Drug", "text": "antiretroviral therapy", "code_expr": null}, {"id": "T... |
NCT00006436 | 2 | 42-year-old man with known HIV infection on antiretroviral therapy presents with newly diagnosed stage III diffuse large B-cell lymphoma confirmed on NCI pathology review; the biopsy is CD20-positive and there is no prior history of lymphoma treatment. He has not received rituximab, only a single prophylactic dose of i... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old man", "code_expr": [{"unit": "year", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "HIV infection", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "HIV infection"}]}, {"id... |
NCT00007878 | 0 | 62-year-old man with metastatic pancreatic adenocarcinoma, biopsy-proven by liver lesion pathology, referred after progression on gemcitabine-based therapy and now receiving best supportive care. He is ambulatory with an ECOG performance status of 1, maintains a fair appetite, and oncology estimates survival at roughly... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "metastatic pancreatic adenocarcinoma", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "biopsy-proven by... |
NCT00007878 | 1 | The patient is a 64-year-old man with biopsy-proven metastatic pancreatic adenocarcinoma, with pathology review confirming advanced disease and no remaining standard curative options. He is ECOG 1, has an estimated life expectancy of several months, and recent labs show ANC 2,300/µL, platelets 168,000/µL, total bilirub... | {"entities": [{"id": "T1", "type": "Person", "text": "64-year-old man", "code_expr": [{"unit": "a", "value": 64.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "metastatic pancreatic adenocarcinoma", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "biopsy-p... |
NCT00007878 | 2 | The patient is a 63-year-old man with biopsy-proven metastatic pancreatic adenocarcinoma, with the specimen previously reviewed and confirmed by the institutional pathology service. He has progressed after prior gemcitabine-based therapy and is now being considered for a phase I study; no curative or standard palliativ... | {"entities": [{"id": "T1", "type": "Person", "text": "63-year-old man", "code_expr": [{"unit": "a", "value": 63.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "metastatic pancreatic adenocarcinoma", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "biopsy-proven", ... |
NCT00009568 | 1 | 58-year-old woman with a long-standing history of major depressive disorder, currently treated with sertraline 100 mg daily for the past 8 weeks with a stable regimen and partial symptomatic benefit. She has no history of bleeding diathesis or platelet disorder, and recent thyroid testing was within normal limits (TSH ... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "major depressive disorder", "code_expr": null}, {"id": "T3", "type": "Drug", "text": "sertraline", "code_expr": null... |
NCT00009568 | 2 | The patient is a 42-year-old woman with a history of major depressive disorder, currently managed with sertraline 100 mg daily for the past 8 weeks with good adherence and no recent dose changes. Symptoms are mild to moderate with low energy and diminished interest, but she denies psychosis, suicidal intent, or any pri... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "major depressive disorder", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "majo... |
NCT00012792 | 1 | A 68-year-old man with longstanding COPD presents for routine pulmonary follow-up with chronic exertional dyspnea, daily wheeze, and a 40 pack-year smoking history, now quit for 2 years. Spirometry shows an FEV1 of 48% predicted with an FEV1/FVC ratio of 58% predicted, consistent with moderate-to-severe obstructive dis... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old man", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "COPD", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "chronic exertional dyspnea", "code_expr": null},... |
NCT00012792 | 2 | The patient is a 68-year-old former smoker with a long-standing diagnosis of COPD, followed in pulmonary clinic for progressive exertional dyspnea and chronic cough with scant sputum. Recent spirometry shows moderate-to-severe obstructive disease with FEV1 at 52% predicted and an FEV1/FVC ratio of 58% predicted, consis... | {"entities": [{"id": "T1", "type": "Person", "text": "68-year-old", "code_expr": [{"unit": "a", "value": 68.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Observation", "text": "former smoker", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "COPD", "code_expr": null}, {"id": "T4", "... |
NCT00013065 | 0 | 52-year-old male with longstanding type 2 diabetes, hypertension, and ischemic cardiomyopathy presents for routine follow-up after recent hospitalization for CHF exacerbation. He is not known to have HIV and has never been prescribed antiretroviral medications; prior infectious disease history is notable only for treat... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old male", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "type 2 diabetes", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": null}, {... |
NCT00013845 | 0 | 58-year-old man with long-standing type 2 diabetes, hypertension, and chronic kidney disease stage 3 was seen in clinic for worsening exertional dyspnea and intermittent chest pressure over the past month. He has no history of seizures, epilepsy evaluation, or neurology referral, and his wife accompanies him as his med... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "type 2 diabetes", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "chronic kidney disease sta... |
NCT00013845 | 1 | The patient is a 34-year-old woman referred to the Clinical Epilepsy Section for longstanding focal seizures since adolescence, currently having intermittent breakthrough events despite levetiracetam and lamotrigine. She is alert and conversational but lacks decision-making capacity due to chronic intellectual disabili... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old woman", "code_expr": [{"unit": "a", "value": 34.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "focal seizures", "code_expr": null}, {"id": "T3", "type": "Temporal", "text": "since adolescence", "code_exp... |
NCT00013845 | 2 | 45-year-old man referred to the Clinical Epilepsy Section for evaluation of recurrent focal seizures since adolescence, with breakthrough events despite levetiracetam and lamotrigine. He is alert but has significant cognitive impairment after a remote traumatic brain injury, and his sister is documented as his health c... | {"entities": [{"id": "T1", "type": "Person", "text": "45-year-old man", "code_expr": [{"unit": "a", "value": 45.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "recurrent focal seizures", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "focal s... |
NCT00022893 | 0 | 62-year-old man with a long-standing history of diffuse large B-cell lymphoma diagnosed on excisional node biopsy, previously treated with I-131 anti-B1 with a partial remission lasting about 5 months before interval enlargement of retroperitoneal and mesenteric nodes on restaging CT. Prior pathology documented CD20-po... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "diffuse large B-cell lymphoma", "code_expr": null}, {"id": "T3", "type": "Procedure", "text": "excisional node biopsy", "code_expr": null}, {"id": "T4", "type": "Drug", "text": "I-131 a... |
NCT00022893 | 1 | 58-year-old man with biopsy-proven diffuse large B-cell non-Hodgkin lymphoma, CD20-positive on prior tissue review, who had a partial remission after I-131 anti-B1 therapy lasting about 6 months before nodal progression over the last 2 months. He has measurable retroperitoneal and right axillary adenopathy on CT, with ... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "diffuse large B-cell non-Hodgkin lymphoma", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "biopsy-proven", "code_expr": null}, {"id": "T4", "type": "Qualifier", "text": ... |
NCT00022893 | 2 | The patient is a 62-year-old man with biopsy-proven diffuse large B-cell non-Hodgkin lymphoma diagnosed 3 years ago, with archived tissue showing strong CD20 positivity by immunohistochemistry. He previously received I-131 anti-B1 radioimmunotherapy and achieved a partial remission lasting about 8 months before interva... | {"entities": [{"id": "T1", "type": "Person", "text": "62-year-old man", "code_expr": [{"unit": "a", "value": 62.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "diffuse large B-cell non-Hodgkin lymphoma", "code_expr": [{"unit": "1", "value": 1.0, "operator": "==", "subject_name"... |
NCT00023192 | 0 | 13-year-old male seen for follow-up of chronic granulomatous disease confirmed by dihydrorhodamine testing with gp91phox deficiency. He has a remote history of severe Serratia bacteremia requiring IV antibiotics at age 8, but no current fevers, cough, skin abscesses, or other evidence of active infection. Weight is 38 ... | {"entities": [{"id": "T1", "type": "Person", "text": "13-year-old male", "code_expr": [{"unit": "a", "value": 13.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic granulomatous disease", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "gp91phox deficiency"... |
NCT00023192 | 1 | 15-year-old male with DHR-confirmed X-linked chronic granulomatous disease due to gp91phox deficiency, weight 48 kg, with a prior history of hospitalization for Serratia bacteremia treated with IV antibiotics. He is currently afebrile and without evidence of active infection; recent labs show creatinine 0.7 mg/dL, tota... | {"entities": [{"id": "T1", "type": "Person", "text": "15-year-old male", "code_expr": [{"unit": "years", "value": 15.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "X-linked chronic granulomatous disease", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "gp91phox ... |
NCT00023192 | 2 | 11-year-old boy with DHR-confirmed X-linked chronic granulomatous disease due to gp91phox deficiency, weight 28.4 kg, followed for recurrent bacterial and fungal infections. He has a prior history of a life-threatening Staphylococcus aureus pneumonia requiring IV antibiotics and hospitalization, but is currently afebri... | {"entities": [{"id": "T1", "type": "Person", "text": "11-year-old boy", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "X-linked chronic granulomatous disease", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "gp91phox deficiency", "code_expr": null}, {"id": "T4", "type": "Value", "text": "... |
NCT00026650 | 1 | The patient is a 46-year-old woman with a history of prior radiotherapy to the retinoblastoma clinic and is being referred back for survivorship follow-up; she is alert, oriented, and able to provide informed consent. She has an established community primary care physician, and records can be forwarded for ongoing mana... | {"entities": [{"id": "T1", "type": "Person", "text": "46-year-old woman", "code_expr": null}, {"id": "T2", "type": "Procedure", "text": "prior radiotherapy", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "retinoblastoma", "code_expr": null}, {"id": "T4", "type": "Observation", "text": "informed consent"... |
NCT00027196 | 1 | 58-year-old woman evaluated in genetics clinic after her brother was diagnosed with familial chylomicronemia syndrome; she meets the study’s family-linkage context as a first-degree relative of an affected proband. She has a history of hypertriglyceridemia managed with fenofibrate, obesity, and well-controlled hyperten... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "familial chylomicronemia syndrome", "code_expr": null}, {"id": "T3", "type": "Observation", "text": "first-degree re... |
NCT00027196 | 2 | Middle-aged woman seen in genetics clinic as the spouse of an affected proband and agrees to participate in the family linkage study. She is generally healthy aside from well-controlled hypertension on lisinopril and seasonal allergies, with no history of malignancy, chronic liver disease, or neurologic complaints. She... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Drug", "text": "lisinopril", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "seasonal allergies", "code_expr": ... |
NCT00033059 | 0 | 34-year-old woman seen in clinic for chronic migraine follow-up and medication refills. She reports daily tobacco use, occasional alcohol intake, and intermittent cannabis use, but denies stimulant use, recent legal issues, or any desire for substance use treatment. Past history is notable for generalized anxiety disor... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old woman", "code_expr": [{"unit": "a", "value": 34.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic migraine", "code_expr": null}, {"id": "T3", "type": "Visit", "text": "clinic", "code_expr": null}, {"id": "T... |
NCT00033059 | 1 | A 34-year-old man presents for screening and reports daily crack cocaine use for the past 6 years, with repeated failed attempts to cut down and clear DSM-IV cocaine dependence features. He is not seeking treatment, states he is here only because of a research flyer, and denies any interest in detox or rehabilitation. ... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old man", "code_expr": [{"unit": "a", "value": 34.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Drug", "text": "crack cocaine", "code_expr": [{"unit": "a", "value": 1.0, "operator": "==", "subject_name": "crack cocaine use"}]}, {"id": ... |
NCT00033059 | 2 | A 32-year-old man presents for research screening after referral from a community outreach program, reporting ongoing crack cocaine use several times weekly with inability to cut down despite repeated attempts; he is not interested in formal treatment and states he is here only for study participation. He meets DSM-IV ... | {"entities": [{"id": "T1", "type": "Person", "text": "32-year-old man", "code_expr": [{"unit": "a", "value": 32.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "cocaine dependence", "code_expr": null}, {"id": "T3", "type": "Drug", "text": "crack cocaine", "code_expr": null}, {"i... |
NCT00033891 | 1 | 52-year-old woman with biopsy-proven dermatomyositis followed for 3 years, with symmetric proximal arm and thigh weakness, heliotrope discoloration, and Gottron papules. Prior workup showed CK 1,840 U/L, aldolase elevated, and EMG with fibrillation potentials; baseline MMT total score is 96/120 and she remains symptoma... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "dermatomyositis", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "symmetric proximal arm and thigh weakness", "code_expr": null}, {"id": "T4", "type": "Condition", "tex... |
NCT00033891 | 2 | 42-year-old woman with a 14-month history of dermatomyositis presents for trial screening. She has symmetric proximal weakness with difficulty rising from a chair and combing her hair; baseline MMT total score is 96/150, and CK remains elevated at 1,240 U/L with mildly high AST/ALT felt to be muscle-related. Prior work... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "dermatomyositis", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "symmetric proximal weakness", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "difficult... |
NCT00033969 | 1 | 42-year-old woman with a 14-month history of right foot and ankle complex regional pain syndrome after a distal fibular fracture, with persistent allodynia, swelling, color change, and marked stiffness despite physical therapy and neuropathic analgesics. She is otherwise in good general health, ambulatory, and agreeabl... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "right foot and ankle complex regional pain syndrome", "code_expr": null}, {"id": "T3", "type": "Condition", "text": ... |
NCT00033969 | 2 | 42-year-old woman referred by pain management for evaluation of chronic regional pain syndrome of the left foot following an ankle sprain 9 months ago, with persistent burning pain, allodynia, swelling, and color/temperature asymmetry consistent with CRPS by Stanton-Hicks criteria. She is otherwise in good general heal... | {"entities": [{"id": "T1", "type": "Person", "text": "42-year-old woman", "code_expr": [{"unit": "a", "value": 42.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "chronic regional pain syndrome of the left foot", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subjec... |
NCT00034021 | 1 | 44-year-old English-speaking woman from Austin presents with decreased libido and anorgasmia that began about 6 weeks after starting sertraline, after an otherwise good antidepressant response. She reports the sexual change is clearly new compared with her baseline, remains in a stable heterosexual relationship, and st... | {"entities": [{"id": "T1", "type": "Person", "text": "44-year-old", "code_expr": [{"unit": "a", "value": 44.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "decreased libido", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "anorgasmia", "code_expr": null},... |
NCT00034021 | 2 | 39-year-old woman from Austin, TX, fluent in English, presents for follow-up of SSRI-associated sexual dysfunction. She has been in a stable heterosexual relationship and reports willingness to attempt intercourse at least twice weekly; she started sertraline 12 weeks ago for well-controlled major depression, and about... | {"entities": [{"id": "T1", "type": "Person", "text": "39-year-old woman", "code_expr": [{"unit": "a", "value": 39.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "SSRI-associated sexual dysfunction", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "sex... |
NCT00036062 | 1 | A 58-year-old woman was admitted with severe hypoxemic respiratory failure after aspiration pneumonia, with bilateral diffuse opacities on chest radiograph and PaO2/FiO2 ratio consistent with acute lung injury. She is intubated and receiving volume-controlled mechanical ventilation with moderate PEEP and FiO2 0.60. Her... | {"entities": [{"id": "T1", "type": "Person", "text": "58-year-old woman", "code_expr": [{"unit": "a", "value": 58.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "severe hypoxemic respiratory failure", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "aspiration pne... |
NCT00036062 | 2 | A 54-year-old man with no history of solid-organ transplantation was admitted with rapidly progressive hypoxemic respiratory failure after severe pneumonia, and chest imaging showed diffuse bilateral alveolar infiltrates consistent with acute lung injury. He is currently intubated and on volume-controlled mechanical ve... | {"entities": [{"id": "T1", "type": "Person", "text": "54-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "no history of solid-organ transplantation", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "rapidly progressive hypoxemic respiratory failure", "code_expr": null}, {"id":... |
NCT00040066 | 0 | 52-year-old man seen in the primary care clinic for poorly controlled hypertension, type 2 diabetes, and chronic low back pain after a work injury. He reports occasional alcohol use and smokes one pack per day, but denies any illicit drug use, including stimulants or opioids, and is not interested in substance use trea... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old man", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "patient age"}]}, {"id": "T2", "type": "Condition", "text": "poorly controlled hypertension", "code_expr": [{"unit": "", "value": 0.0, "operator": "==", "subject_name": "h... |
NCT00040066 | 1 | A 38-year-old man with a long-standing crack cocaine use disorder presents for routine primary care, reporting daily use for the past several years and no interest in detoxification, rehabilitation, or other treatment services. He meets criteria for cocaine dependence by history, with recurrent binges, inability to cut... | {"entities": [{"id": "T1", "type": "Person", "text": "38-year-old man", "code_expr": [{"unit": "a", "value": 38.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "crack cocaine use disorder", "code_expr": [{"unit": "", "value": 1.0, "operator": "==", "subject_name": "crack cocaine... |
NCT00040066 | 2 | Mr. A is a 34-year-old man with a long history of cocaine use, reporting near-daily intranasal and intermittent smoked use over the past 6 years, with cravings, loss of control, and continued use despite work and relationship problems consistent with cocaine dependence. He states he is not interested in formal substanc... | {"entities": [{"id": "T1", "type": "Person", "text": "34-year-old man", "code_expr": [{"unit": "a", "value": 34.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "cocaine dependence", "code_expr": null}, {"id": "T3", "type": "Drug", "text": "cocaine", "code_expr": null}, {"id": "T... |
NCT00043732 | 1 | 52-year-old woman with seropositive rheumatoid arthritis meeting 1987 ARA criteria, with persistent inflammatory polyarthritis despite methotrexate 20 mg weekly and folic acid. Exam shows 10 tender and 7 swollen joints, morning stiffness lasting about an hour, ESR 42 mm/hr, and CRP 1.6 mg/dL. She has a remote history o... | {"entities": [{"id": "T1", "type": "Person", "text": "52-year-old woman", "code_expr": [{"unit": "a", "value": 52.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "seropositive rheumatoid arthritis", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "persistent inflam... |
NCT00043732 | 2 | Middle-aged woman with longstanding seropositive rheumatoid arthritis meeting the 1987 ARA criteria, with symmetric MCP/PIP involvement, morning stiffness lasting about an hour, and persistent synovitis despite therapy. She remains on weekly methotrexate with folic acid and has active disease today with 9 tender and 6 ... | {"entities": [{"id": "T1", "type": "Person", "text": "Middle-aged woman", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "seropositive rheumatoid arthritis", "code_expr": null}, {"id": "T3", "type": "Qualifier", "text": "longstanding", "code_expr": null}, {"id": "T4", "type": "Qualifier", "text": "symmet... |
NCT00044057 | 1 | A 67-year-old man with sudden right-sided weakness and aphasia was last seen normal 90 minutes before ED arrival and received IV alteplase promptly after noncontrast head CT showed no hemorrhage. He is awake, follows simple commands, and his NIHSS is 15 with dense arm drift, facial droop, and moderate dysarthria. Past ... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": [{"unit": "a", "value": 67.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "sudden right-sided weakness", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "aphasia", "code_expr": nu... |
NCT00044057 | 2 | 67-year-old man with a history of hypertension, hyperlipidemia, and well-controlled type 2 diabetes was brought in by EMS after sudden onset of right facial droop and dense right arm weakness while eating breakfast; he was last known well 1 hour and 20 minutes prior to arrival. He remained awake and interactive on exam... | {"entities": [{"id": "T1", "type": "Person", "text": "67-year-old man", "code_expr": null}, {"id": "T2", "type": "Condition", "text": "hypertension", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "hyperlipidemia", "code_expr": null}, {"id": "T4", "type": "Condition", "text": "type 2 diabetes", "code_exp... |
NCT00044473 | 0 | 8-year-old girl with a history of seasonal allergic rhinitis and well-controlled asthma presented with 2 days of nasal congestion, low-grade fever, and left ear discomfort after a recent viral URI. Exam showed an erythematous, opaque tympanic membrane with reduced mobility and mild effusion, but no otorrhea, no mastoid... | {"entities": [{"id": "T1", "type": "Person", "text": "8-year-old girl", "code_expr": [{"unit": "a", "value": 8.0, "operator": "==", "subject_name": "age"}]}, {"id": "T2", "type": "Condition", "text": "seasonal allergic rhinitis", "code_expr": null}, {"id": "T3", "type": "Condition", "text": "well-controlled asthma", "c... |
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