mutant_file_id,doi
1A3G_kcatkm57_alpha-Ketoglutarate,10.1021/acscatal.9b01464
1A6K_ee,doi.org/10.1002/anie.201608680
1BXZ_ee,doi.org/10.1002/cbic.201700562
1MLC_2_Kd-wtKd-mut,http://dx.doi.org/10.1038/nbt1336
1NWW_ee,doi.org/10.1021/jacs.7b10278
1XWW_activity,10.1371/journal.pone.0235133
1XWW_kcatkm,10.1371/journal.pone.0235133
1XWW_km,10.1371/journal.pone.0235133
1Z42_ee_1,doi.org/10.1002/adsc.200900644
1Z42_ee_2,doi.org/10.1002/adsc.200900644
1Z42_ee_3,doi.org/10.1002/adsc.200900644
2Q0Q_ee_1,doi.org/10.1021/acscatal.0c01767
2Q0Q_ee_2,doi.org/10.1021/acscatal.0c01767
2YLR_ee,doi.org/10.1021/ja5098034
3FCR_activity-substrate-1,10.1021/acscatal.4c00987
3FCR_activity-substrate-2,10.1021/acscatal.4c00987
3FCR_ee,10.1021/acscatal.4c00987
3WUY_ee,10.1002/anie.202012243
4DF2_ee,10.1021/cs500429k
4O98_kcat,10.1002/bit.26012
4O98_kcatkm,10.1002/bit.26012
4O98_km,10.1002/bit.26012
4OVI_ee_2,doi.org/10.1021/ja5098034
4OVI_ee_3,doi.org/10.1021/ja5098034
4OVI_ee_4_substreate_1a,doi.org/10.1021/ja5098034
4OVI_ee_4_substreate_4b,doi.org/10.1021/ja5098034
4OVI_ee_4_substreate_4c,doi.org/10.1021/ja5098034
4S2P_kcatkm,10.1038/s41929-024-01117-4
5A71_ee,doi.org/10.1021/jacs.9b02709
5A71_kcat,10.1038/s41467-019-11155-3
5A71_kcatkm,10.1038/s41467-019-11155-3
5A71_km,10.1038/s41467-019-11155-3
5T6M_km,10.1021/jacs.8b03490
5Z2X_ee,doi.org/10.1021/jacs.8b08640
6CUK_turnover_rate,10.1038/s41467-024-50698-y
6JXG_activity,10.1186/s13068-021-01973-3
7EMG_ee,10.1039/d1cc04542c
7LOO_activity,10.1021/acs.jafc.4c03715
7YVR_activity,doi.org/10.1021/acscatal.0c05607
7YVR_de,doi.org/10.1021/acscatal.0c05607
8IOZ_activity,10.1016/j.isci.2024.109034
A0A059TC02_activity,10.1105/tpc.114.127399
A0A0H2V871_DGE_activity,10.1021/bi060950i
A0A0H2V871_Ent_activity,10.1021/bi060950i
A0A0I9QGZ2_ee_1,doi.org/10.1039/c4cc08436e
A0A0I9QGZ2_ee_2,doi.org/10.1039/c4cc08436e
A0A0I9QGZ2_kcat,10.1002/anie.201701169
A0A0I9QGZ2_kcatkm,10.1002/anie.201701169
A0A0I9QGZ2_km,10.1002/anie.201701169
A0A0K8P6T7_activity,10.1002/cbic.201800097
A0A0K8P6T7_TPA_activity,10.1002/cbic.201800097
A0A0K8P6T7_yield,10.1002/cbic.201800097
A0A0K8P8E7_activity,10.1038/s41467-019-09326-3
A0A0P0ZBS7_activity,10.1007/s12033-015-9839-4
A0A7I6N400_ee,10.1021/acsomega.0c03070
A0MGZ7_substrate_VII_activity,10.1021/acschembio.6b00841
A0MGZ7_substrate_VI_activity,10.1021/acschembio.6b00841
A0MGZ7_substrate_V_activity,10.1021/acschembio.6b00841
A2QAN3_kcat,?10.1111/febs.14083
A2QAN3_kcatkm,?10.1111/febs.14083
A2RJT9_DCIP_activity,10.1074/jbc.M303767200
A2RJT9_oxygen_activity,10.1074/jbc.M303767200
A4QAA6_activity,doi/10.1021/acs.jafc.3c09589
A4XGA6_M5_Epimerization_activity,10.1016/j.ijbiomac.2019.11.015
A4XGA6_M5_Isomerization_activity,10.1016/j.ijbiomac.2019.11.015
AAD07447_1_activity_product_3-FL,10.1002/bit.25944
AAD07447_1_activity_product_Lex,10.1002/bit.25944
AAD07447_1_kcatkm_substrate_GDP,10.1002/bit.25944
AAD07447_1_kcatkm_substrate_lactose,10.1002/bit.25944
AAD07447_1_kcat_substrate_GDP,10.1002/bit.25944
AAD07447_1_kcat_substrate_lactose,10.1002/bit.25944
AAD07447_1_km_substrate_GDP,10.1002/bit.25944
AAD07447_1_km_substrate_lactose,10.1002/bit.25944
AB333782_activity,10.1016/j.enzmictec.2024.110481
ABS64560_1_activity,10.1007/s00253-015-6527-z
ACCO_ee,10.1038/s44160-024-00536-2
ACY56506_1_km,10.1128/AEM.01817-16
AGQ46835_1_kcat,10.1016/j.enzmictec.2015.12.012
AGQ46835_1_kcatkm,10.1016/j.enzmictec.2015.12.012
AGQ46835_1_km,10.1016/j.enzmictec.2015.12.012
AHW42593_1_activity,10.1016/j.enzmictec.2018.03.001
AHZ56660_1_kcat,10.1111/1751-7915.12168
AHZ56660_1_km,10.1111/1751-7915.12168
ALB07219_1_activity,10.1007/s00449-020-02393-7
ASG2_exp,10.1002/biot.202400347
BAA88830_1_activity,10.1186/s12934-020-01451-9
BAA_activity,10.1021/acs.jafc.4c05070
BsSDR10_R-R-R-2_de,10.1021/jacsau.4c00284
BsSDR10_R-S-S-2_de,10.1021/jacsau.4c00284
BsSDR10_S-R-R-2_de,10.1021/jacsau.4c00284
BsSDR10_S-S-S-2_de,10.1021/jacsau.4c00284
BsSDR10_S7_R-R-R-2_de,10.1021/jacsau.4c00284
BsSDR10_S7_R-S-S-2_de,10.1021/jacsau.4c00284
BsSDR10_S7_S-R-R-2_de,10.1021/jacsau.4c00284
BsSDR10_S7_S-S-S-2_de,10.1021/jacsau.4c00284
C6DAH4_activity,10.1002/cbic.201700609
CCA64021_1_activity,10.1007/s12010-019-03170-3
CQR83192_1_activity,10.1007/s10529-018-2607-3
CQR83192_1_kcat,10.1007/s10529-018-2607-3
D4Z2G1_activity,10.1021/bi026427v
E8RUP5_activity,10.1021/jacs.6b10389
EHK72968_1_ee,10.1016/j.bbrc.2015.11.038
EIJ78397_1_kcatkm,10.1021/acssynbio.8b00481
EU348855_E-value,10.3390/molecules29204864
GAP38373_1_relative_kcat,10.1002/cbic.202300373
I6XD65_NAM_activity,10.1111/j.1742-4658.2007.06241.x
I6XD65_PZA_activity,10.1111/j.1742-4658.2007.06241.x
KAL2709656_de,doi.org/10.1021/acscatal.0c05607
KdAKR_activity,10.1002/biot.202300637
KE07_kcat,10.1038/nature06879
KE70_kcatkm,10.1038/nature06879
KmAKR_variant_3_activity,10.1016/j.bioorg.2021.104712
MN539024_1_km,10.1111/1751-7915.13812
MT038422_1_activity_hydrolysis,10.1016/j.enzmictec.2020.109644
MT038422_1_activity_transpeptidation,10.1016/j.enzmictec.2020.109644
MT038422_1_kcat,10.1016/j.enzmictec.2020.109644
MT038422_1_kcatkm,10.1016/j.enzmictec.2020.109644
MT038422_1_km,10.1016/j.enzmictec.2020.109644
myoglobin_ee,http://dx.doi.org/10.1016/j.chempr.2024.06.010
nitrilase_ee,?10.1021/ja035742h
O06543_activity,10.1074/jbc.M409704200
O52063_activity,10.1371/journal.pone.0137700
O54728_activity,10.1021/bi010237n
O75355_ADPase_activity,10.1021/bi002711f
O75355_ATPase_activity,10.1021/bi002711f
O94220_activity,10.1016/j.fob.2013.10.009
P00813_activity,10.1096/fj.12-212621
P04517_exp,10.1016/j.jbiotec.2005.08.006
P05030_activity,10.1002/j.1460-2075.1988.tb03010.x
P05150_activity,10.1074/jbc.M300383200
P06802_activity,10.1074/jbc.M007552200
P08684_ee_1,doi.org/10.1002/cbic.201600546
P08684_ee_2,doi.org/10.1002/cbic.201600546
P0A2M9_kcatkm,10.1016/j.molcel.2007.11.011
P0A2M9_vmax,10.1016/j.molcel.2007.11.011
P0A873_vmax,10.1016/j.jmb.2003.09.011
P0A8I5_kcat,10.1002/prot.20454
P0ADG7_kcat,10.1021/bi9714161
P11509_kcat,10.1080/15287394.2014.951757
P11509_kcatkm,10.1080/15287394.2014.951757
P11509_kd,10.1080/15287394.2014.951757
P11509_km,10.1080/15287394.2014.951757
P14779_ee,10.1002/cbic.201200244
P14779_ee_2,10.1002/cbic.201200244
P14779_ee_3,10.1002/cbic.201200244
P15042_1_activity,10.1074/jbc.M111164200
P15042_2_activity,10.1074/jbc.M413685200
P22862_activity,10.1002/bit.27170
P24058_vmax,10.1074/jbc.M107465200
P25745_activity,10.1038/nature04896
P27346_activity_aKG,10.1021/acscatal.2c04636
P27346_activity_PBO,10.1021/acscatal.2c04636
P27346_activity_PPO,10.1021/acscatal.2c04636
P27346_activity_PTO,10.1021/acscatal.2c04636
P27346_PBO_kcat,10.1021/acscatal.2c04636
P27346_PBO_KcatKm,10.1021/acscatal.2c04636
P27346_PBO_Km,10.1021/acscatal.2c04636
P27346_PPO_kcat,10.1021/acscatal.2c04636
P27346_PPO_kcatkm_csv,10.1021/acscatal.2c04636
P27346_PPO_km,10.1021/acscatal.2c04636
P29379_ee,10.1002/bit.26484
P32738_kcat,10.1074/jbc.270.49.29111
P33018_kcatkm,10.1074/jbc.M600996200
P33018_vmax,10.1074/jbc.M600996200
P36136_kcat,10.1074/jbc.M110.118315
P36136_vmax,10.1074/jbc.M110.118315
P46544_activity,10.1016/s0167-4838(98)00264-7
P46849_activity,10.1016/j.str.2010.01.016
P49768_1_activity,10.1038/nature14892
P51697_activity,?10.1002/prot.10007
P52061_kcat,10.1016/j.jmb.2007.10.012
P56653_kcat,10.1021/bi0262303
P58004_kcat,10.1038/ncomms10025
P73574_activity,?10.1016/j.febslet.2015.09.001
P73832_activity,10.1016/j.jmb.2009.07.001
P77555_kcat,10.1371/journal.pone.0052066
P77555_kcatkm,10.1371/journal.pone.0052066
P78330_activity,10.1074/jbc.M204866200
P80036_activity,10.1271/bbb.65.1542
P95480_vmax,10.1002/anie.200802466
P95867_activity,10.1021/jf073320b
P9WHH9_DTNB_activity,10.1074/jbc.M507466200
P9WHH9_LDH_activity,10.1074/jbc.M507466200
P9WHH9_PDH_activity,10.1074/jbc.M507466200
Q02353_N_deacetylase_activity,10.1074/jbc.274.4.1966
Q02353_N_sulfotransferase_activity,10.1074/jbc.274.4.1966
Q02890_activity,10.1074/jbc.M111383200
Q03154_kcat,10.1074/jbc.M304233200
Q06135_activity,10.1074/jbc.M807990200
Q071N0_kcatkm,10.1074/jbc.M109.030957
Q14RS0_activity,10.1016/j.enzmictec.2015.07.009
Q16769_kcat,10.1073/pnas.0504184102
Q16774_kcat,10.1074/jbc.RA119.009251
Q2FHP2_activity,10.1038/s41467-019-13724-y
Q2FV54_activity,10.1074/jbc.RA120.013108
Q3YW59_activity,10.1038/nature13618
Q44244_NSAR_kcat,10.1021/bi500573v
Q44244_OSBS_kcat,10.1021/bi500573v
Q47NX5_km,10.1128/AEM.01224-18
Q4KAC6_kcat,10.1016/j.enzmictec.2019.01.002
Q4KAC6_kcatkm,10.1016/j.enzmictec.2019.01.002
Q4KAC6_km,10.1016/j.enzmictec.2019.01.002
Q51559_activity,10.1111/febs.14954
Q57261_activity,10.1016/j.abb.2009.07.023
Q58431_activity,10.1021/bi0484769
Q597B8_activity,10.1016/j.ijbiomac.2024.132084
Q5F4D9_ee,10.1002/anie.201311091
Q65EX3_activity,10.1073/pnas.1019480108
Q6VAB4_kcatkm,10.1073/pnas.1902104116
Q70PR7_activity,?10.1016/j.bmc.2004.02.029
Q7SIG4_activity,10.1021/bi0500675
Q86GC8_activity,10.1016/j.scitotenv.2024.173282
Q86XE5_kcat,10.1371/journal.pone.0026021
Q887Q3_activity,10.1074/jbc.M113.533158
Q88LS1_activity,10.1128/mBio.01412-17
Q8GCH2_kcat,?10.1074/jbc.M801227200
Q8IYT2_activity,10.1038/ncomms4004
Q8JFY9_activity,10.1074/jbc.M501160200
Q8KLM3_activity,10.1074/jbc.M611912200
Q8LPL7_activity,?10.1093/nar/gkz070
QNC43959_1_kcatkm_substrate_R,10.1038/nature06879
QNC43959_1_kcatkm_substrate_S,10.1038/nature06879
QNC43959_1_kcat_substrate_R,10.1038/nature06879
QNC43959_1_kcat_substrate_S,10.1038/nature06879
QNC43959_1_ratio_of_kcatkm_R_over_S,10.1038/nature06879
S5Y0Y3_residual_activity,10.1016/j.bbrc.2020.12.039
S5Y0Y3_turn_over_frequency,10.1016/j.bbrc.2020.12.039
Tr_Cel7B_activity,10.1021/ci500339v
WLF46330_1_kcat_disulfide_bonds,10.1002/bit.28808
WP_012492804_activity,doi.org/10.1128/AEM.02688-15
WP_012492804_ee,doi.org/10.1128/AEM.02688-15
firprotdb**，10.1093/nar/gkaa981
M1261**,10.1038/s43588-024-00716-2
thermomutdb**,10.1093/nar/gkaa925
Q306**,10.1093/bioinformatics/btw361
S571**,10.1038/s43588-024-00716-2
S669**,10.1093/bib/bbab555
s2648**,10.1093/bioinformatics/btp445
S4346**10.1038/s43588-024-00716-2
S8754**,10.1038/s43588-024-00716-2
vb1432**,10.3390/ijms19041009
PPB_Affinity**,10.1038/s41597-024-03997-4