---
license: cc-by-4.0
task_categories:
- tabular-classification
- regression
tags:
- medical
- oncology
- synthetic-data
- genomics
- ehr
- nsclc
- bioinformatics
pretty_name: ANODE Synthetic Oncology & Genomics
---

# ANODE: Synthetic NSCLC EHR & Genomics Dataset

## Title: ANODE-OncoGen High-Fidelity Synthetic Records

This dataset consists of a high-density `.jsonl` collection of synthetic patient records for Non-Small Cell Lung Cancer (NSCLC), integrating clinical history with deep genomic markers.



### 📋 Full Feature Specifications
The dataset includes the following features for every patient record:

#### 1. Administrative & Metadata
* **patient_id**: Unique identifier for the synthetic patient (e.g., `ANODE_551499`).
* **record_id**: Unique identifier for the specific clinical event.
* **record_generation_timestamp**: ISO 8601 timestamp of data simulation.
* **synthetic_source**: Versioning information for the Grok-4 high-fidelity simulator.

#### 2. Clinical Demographics
* **age_at_diagnosis**: Patient age in years.
* **sex**: Biological sex (male/female).
* **smoking_pack_years**: Quantitative history of tobacco use.
* **ecog_performance_status**: Functional status score (0–4) indicating the patient's level of self-care.

#### 3. Oncology & Histology
* **cancer_type**: Specific malignancy (Non-small cell lung cancer).
* **histology**: Cellular classification (e.g., Adenocarcinoma, Squamous cell carcinoma).
* **stage_at_diagnosis**: Disease progression stage (e.g., IVA, IVB).
* **primary_tumor_size_cm**: Diameter of the primary lesion in centimeters.
* **metastatic_sites_count**: Numerical count of secondary tumor locations.



#### 4. Genomic & Biomarker Profile
* **driver_mutation**: Identified genetic drivers (e.g., ALK fusion, EGFR, KRAS, BRAF, or None).
* **pd_l1_tps_percent**: Tumor Proportion Score for PD-L1 expression (0–100%).
* **tmb_mutations_per_mb**: Tumor Mutational Burden measured in mutations per megabase.
* **msi_status**: Microsatellite instability status (e.g., MSS).

#### 5. Treatment & Survival Outcomes
* **first_line_regimen**: Initial therapy used (e.g., carboplatin + paclitaxel + pembrolizumab).
* **overall_survival_months**: Time elapsed from diagnosis to death or last follow-up.
* **censored**: Boolean flag (true/false) indicating if the patient was still alive at the end of the simulation period.



### 📂 Technical Format
* **File Extension**: `.jsonl` (JSON Lines)
* **Encoding**: UTF-8
* **Schema Consistency**: Strict key-value pairing across all entries for programmatic parsing.
*