67-year-old asymptomatic woman with hepatic metastatic renal cell carcinoma who presented with organizing pneumonia after radioembolization treatment. (b) Catheter angiography demonstrates hypervascular metastases supplied by three arterial conduits.


67-year-old asymptomatic woman with hepatic metastatic renal cell carcinoma who presented with organizing pneumonia after radioembolization treatment. (c) Postradioembolization bremsstrahlung SPECT/CT demonstrates activity within the targeted angiosomes covering both tumors and a margin.


Course of treatment of this patient over time.


Paucity of the cortical veins and non visualized right transverse sinus. Is reversed following CSF drainage with distension of the sinuses.


Better visualization of the cortical veins. In this TOF venogram.


CRP course (black) and course of body temperature (grey) over 12 days after positive SARS-CoV-2-antigen test. CRP concentration was measured in plasma. Fever decreased 8 days after positive SARS-CoV-2 test during the last CRP apheresis. Grey boxes indicate the four apheresis treatments (A1-4).


Clinical course of the patient. (A) Stage 1: from pathogeny to intubation.


Clinical course of the patient. (B) Stage 2: ECMO stage.


Clinical course of the patient. (C) Stage 3: transplant and post-transplant stages.


Microscopic examination of the explanted lung (hematoxylin-eosin stain, x50) shows extensive consolidation of lung tissue and pulmonary interstitial fibrosis (arrowheads). Ring fibrosis connecting alveolar orifice rings and inflammatory cell infiltration into the alveolar walls with pneumocyte hyperplasia and squamous metaplasia.


Brain magnetic resonance imaging at the time of diagnosis. There is a recognizable, voluminous expansive lesion at the hypothalamic level. FLAIR sequence) with an inhomogeneous structure.


Brain magnetic resonance imaging at the time of diagnosis. First read as calcifications. T1 sequence.


Brain magnetic resonance imaging at the time of diagnosis. . T2 sequence). Optic chiasma, hypothalamic-pineal peduncle and mammillary body are not recognizable.


Brain magnetic resonance imaging at the time of diagnosis. (D, T2W_TSE sequence).


Plain radiograph of the chest shows the Denver shunt placed in the pleural cavity (arrow) and the venous end directed toward the right internal jugular vein.


A line diagram of the Denver pleurovenous shunt shows the proximal part of the tube within the pleural cavity and the distal or venous end of the catheter inserted into the internal jugular vein, with its distal end extending to the superior vena cava. The pump within the chest wall allows manual compression and creates a unidirectional flow of fluid from the pleural cavity to the central venous system (arrows).


Gray-scale ultrasound scan of the right side of the neck shows the venous end of the Denver shunt (arrow) within the right internal jugular vein.


Ultrasound scan of the right chest wall demonstrates the pleural end of the Denver shunt catheter placed subcutaneously (arrow).


Transverse ultrasound scan over the lump on the right side of the neck shows fluid collection measuring 5.5 cm x 3.4 cm anterior to the internal jugular vein. Catheter is seen within the right internal jugular vein (arrow).


Electroencephalogram recorded on day 8. Encephalopathy is suspected because of the diffuse slowing of the background activity.


Chest CT scan (11.30.2017) shows a 4.1 x 3.9-cm lung mass in the left pulmonary hilum area. (A) Lung window.


Chest CT scan (11.30.2017) shows a 4.1 x 3.9-cm lung mass in the left pulmonary hilum area. (B) Mediastinal window.


Chest CT scan (05.16.2018) shows a 7.5 x 6.7-cm lung mass in the left pulmonary hilum area. (A) Lung window.


Chest CT scan (05.16.2018) shows a 7.5 x 6.7-cm lung mass in the left pulmonary hilum area. (B) Mediastinal window.


(A) The bronchoscopy examination showed tumor of the left lower superior segment obstructed bronchus.


(B) Tumor of the left upper lobe obstructed bronchus.


Immunohistochemical examination:. The left lower superior segment was squamous cell carcinoma.


It was positive for P40, P63, CK(Pan), negative for TTF-1, CK7, NapsinA.


The left upper lobe was small cell lung carcinomas.


The tumor cells were positive for. Ki67(+80%), CD117, CK(Pan), P53, CgA.


SYN, and negative for LCA.


Chest CT scan (08.22.2018) shows a 7.1 x 4.0-cm lung mass in the left pulmonary hilum area. (A) Lung window.


Chest CT scan (08.22.2018) shows a 7.1 x 4.0-cm lung mass in the left pulmonary hilum area. (B) Mediastinal window.


Chest CT scan (11.06.2018) shows a 7.1 x 6.2-cm lung mass in the left pulmonary hilum area. (A) Lung window.


Chest CT scan (11.06.2018) shows a 7.1 x 6.2-cm lung mass in the left pulmonary hilum area. (B) Mediastinal window.


CT Abdomen showed 3.5 x 2.5 cm primary tumour in pancreatic head/uncinate process mass with complete encasement of superior mesenteric artery (SMA)/superior mesenteric vein (SMV). No evidence of any regional lymphadenopathy or liver metastasis. The figure illustrates the approximate extent of pancreatic mass (circled), pancreatic duct dilatation (yellow arrow) and the narrow superior mesenteric artery (red arrow).


CT Abdomen showing severe anasarca and retroperitoneal haemorrhage. The figure shows the bilateral retroperitoneal haemorrhages both right sided (thick arrow) and left sided (thin arrow). It illustrates the asymmetry with right side retroperitoneal haemorrhage being larger in size.


Increasing factor VIII level as chemotherapy was given, also shows timeline of other used immunosuppressive therapies.


Alopecia universalis.


Grouped fasciculations.


Continuous motor unit activity observed from thoracic paraspinal muscle.


Fluoroscopic image of the patient in Case 3 demonstrating placement of two embolization coils in right upper lobe.


Electrocardiogram of patient at the time of admission.


Pulmonary computed tomography angiography of the patient.


T2-weighted mid-sagittal image centered at T3. Long contiguous segment (T3 to T6) central T2 hyperintense lesion mildly expanding the cord.


T2-weighted mid-sagittal image proximal to the level on previous image shows long segment expansion of the central canal (syrinx).


Axial T2-weighted image at the level of T3 revealed central cord hyperintensity.


Transthoracic echocardiography on admission and four days later after percutaneous coronary intervention (PCI). Echocardiography on admission showing global hypokinesia, mild mitral regurgitation (MR) and left atrium (LA) enlargement (LA volume, 54 mL) (A, B).


Transthoracic echocardiography on admission and four days later after percutaneous coronary intervention (PCI). Four days later after PCI, left ventricular contraction and LA enlargement have improved (LA volume, 34 mL), and MR has resolved (C, D).


Coronary artery angiography during the primary percutaneous coronary intervention. (A) Left coronary angiography showing significant stenosis from the distal left main coronary artery to the mid left anterior descending artery with thrombolysis in myocardial infarction (TIMI) 2 flow and total occlusion at the ostium of the left circumflex artery with TIMI 0 flow.


Coronary artery angiography during the primary percutaneous coronary intervention. (B) Final coronary angiography showing successful revascularization without periprocedural complications.


Computed tomography scan revealing consolidation and ground-glass opacity in the dependent portion of the right lung, with pleural effusion limited to the right lung.


Chest computed tomography (CT) revealing the 2 pulmonary nodules (indicated by arrows) of which CT-guided transthoracic needle biopsies were performed:. 16 mm nodule in the left lower lobe.


9 mm nodule in the right lower lobe.


Pre-operative photograph.


Post-operative photograph.


Excised lesion.


Photomicrograph of the specimen.


Healing after 1 week.


Healing after 3 weeks.


Density in the stomach fundus, suspicious for an aspirin bezoar (pointed by arrow).


Chest x-ray showed airspace opacity is noted in the left perihilar region.


Ultrasound examination of the lesion in the lower chest wall showed well defined hypoechoic area, with varying degrees of internal heterogeneity.


(a-d) Brain computed tomography revealed multiple air images.


Timeline of abdominal CT and plain radiography findings. A; Plain abdominal radiograph at the time of first admission showing linear calcification in the ascending colon (arrowheads).


Timeline of abdominal CT and plain radiography findings. B; CT of the abdomen at the time of first admission showing thickening of the ascending colon and calcification of the mesenteric vessels (arrowheads). The small intestines are seen to be dilated (arrows).


Timeline of abdominal CT and plain radiography findings. C; CT of the abdomen 2 months later showing thickening of the bowel walls from the ascending to the transverse colon and calcification of the mesenteric veins (arrowheads). The small intestine no longer appears dilated.


Representative colonoscopy image at the time of first admission demonstrating the presence of dark purple edematous mucosa; this was seen to extend from the transverse colon to the cecum.


Representative microscopic examination image at the time of first admission demonstrating proliferation of collagen fibers and moderate hyalinization adjacent to capillaries.


Chest radiograph and CT scans of Case 1 showing elevation of bilateral hilar opacities and subpleural reticular opacities in the bilateral lung fields.


The patient's serum creatinine (Cr) level over a 4-year period.


The patient's hemoglobin level over a 4-year period.


Chest X-ray . A; Chest X-ray revealed thickened lung marking in both lower lung fields.


CT scan. On admission. B; Chest CT scan showed honeycombing, reticular and ground glass opacities in the lower lung fields (arrows).


Chest CT scan showing anterosuperior mediastinal mass before. Arrow), and . A; The size of the anterosuperior mediastinal mass was 3.5 x 1.9 cm with CT 5 HU.


After. Arrow) treatment. B; The same mass was diminished to 1.2 x 1.0 cm with CT 16 HU.


Illustration depicting intraoperative findings in the patients neurolysis surgery depicting fibrous bands and a vascular leash constricting the common peroneal nerve at the level of the popliteal fossa.


Patient chest x-ray. Patient lungs are shown to be clear.


Chest X-ray.


Thoracic ultrasound. Images showing a large left-sided pleural effusion.


Thoracic ultrasound. Images showing near-complete resolution of the left-sided pleural effusion post intrapleural fibrinolytic therapy and drainage.


Computed tomography images of a 76-year-old female with lipoid pneumonia revealed ground-glass opacities and bronchiectasis in both lungs.


Medical image.


The shadows improved 2 years later (c).


CT Chest shows multifocal patchy airspace opacities and small pleural effusions.


Chest radiograph done on day 6 shows improvement in bilateral infiltrates.


Chest radiograph done after discharge showed resolution of pulmonary infiltrates.


Bronchoscopy revealing mucopurulent tracheobronchitis and a well-demarcated area of increased friability with white-colored pseudomembrane involving the carina and right upper bronchus.


Brushing from the pseudomembrane showing clusters of septate fungal hyphae with a positive potassium hydroxide (KOH) preparation.


Thorax CT shows cylindrical bronchiectasis and thick bronchial walls. Lung parenchyma is mostly unchanged. (Department of Radiology of Philipps-University Marburg).


Analysis of 100 patients with ulcerative colitis (UC).


Overview of some previous publications on lung involvement in ulcerative colitis (UC).


CT showing massive bilateral AMLs and hematoma formation on right upper pole. AML, angiomyolipoma.


Angiogram, pre-gelfoam, and tornado coils. Bleeding in upper pole identified.


Postembolization. Note absence of contrast extravasation beyond the coils.


FDG PET/CT shows increased uptake in the inguinal lymph nodes (arrow in A) with no significant uptake in the lung nodules (arrow in B).


Chest X-ray PA view of the patient on the day of admission shows a "continuous diaphragm sign" characterised by a mediastinal gas outlining the superior surface of the diaphragm and separating it from the heart (black arrowheads) and a "Naclerio's V sign" in which mediastinal gas outlines the lateral margin of the descending aorta and extends laterally over the left hemidiaphragm (red arrowheads).


Chest X-ray (lateral view) demonstrating lucency (Yellow arrows) overlying the heart signifying pneumopericardium.


CT imaging demonstrating dissection of fascial planes in neck and invasion of trapped air into the spinal canal (yellow arrows) via intervertebral foramen.


STROBE diagram depicting the selection process stepwise during the literature search for articles on nonspontaneous pneumorachis.


Axial non-contrasted computed tomography demonstrates a large, multiseptated focal collection of gas in the subcutaneous tissue overlying the left parotid gland (white arrowhead). Underlying communication with branching gas pattern in the ductal system of the left parotid gland is shown (black arrow). No gas is present in the parapharyngeal fat space or deep neck spaces.


Magnified axial non-contrasted computed tomography with soft tissue window again demonstrates the gas-filled branching parotid ductal pattern (white arrow). The left parotid gland appears otherwise morphologically normal, with no features of inflammation.


Magnified axial non-contrasted computed tomography demonstrating gas in the mildly distended left Stenson's (parotid) duct (black arrowhead).


Chest radiographs on admission. (A) Chest plain radiograph shows diffuse reticulonodular densities in both central lung areas symmetrically.


Chest radiographs on admission. (B) On computed tomographic image with lung window setting, diffuse bronchiectasis is seen in both lungs. There are hyperlucent areas in the lung parenchyma due to peripheral bronchial obstruction.


CAMP-activated Cl- channel activity of L441P mutant CFTR. HEK 293 cells were transfected with plasmids for wild type CFTR or CFTR carrying the L441P mutation and the cAMP-activated Cl- channel activity was measured in the whole cell configuration. (B) The I-V relationships were obtained with a step pulse from -120 mV to +120 mV applied at peak current.


Three-dimensional topology of selected missense mutations in complement factor I (light gray) and their relationship with C3b (dark gray). (A) P64 residue of complement factor I forms a contact point with V1658 of C3b (blue). Q88 lies in close apposition to this contact site.


Three-dimensional topology of selected missense mutations in complement factor I (light gray) and their relationship with C3b (dark gray). (B) G71 (previously reported by Broderick et al and associated with a similar clinical phenotype) lies on a side chain between P64 and Q88. Figures produced using PyMOL v2.2 using a crystal structure of CFI and C3b solved to a resolution of 4.2 A (Protein Data Bank Reference - 5O32).


Advance hemodynamic parameters.


Magnetic resonance imaging showing abnormal signal intensity from C2 to C4.


A large number of hemosiderin-laden macrophages and foci of fresh hemorrhage were determined. H and E, x100 and Prussian blue, x100.


The renal biopsy findings. . Notes: A light micrograph (A) shows the glomerulus accompanied by the slight expansion of the mesangial matrices with mesangial cell proliferation (Periodic acid-Schiff staining).


The renal biopsy findings. Immunofluorescence microscopy (B) shows granular staining for IgA limited to the mesangium. The scale bar is indicated in each panel. . Abbreviation: Ig, immunoglobulin.


Intraoperative situs after removal of the hemangioma. The lines indicate the vena cava.


Ultrasonography on day X reveals a hypoechoic lesion with ill-defined margins and irregular form, appearing avascular and heterogeneous (a).


Computed tomography of the neck on admission (day X + 5) also reveals a low-density lesion in the right thyroid gland, 37 x 37 x 42 mm in size with enhancement in the marginal area (b).


Cytology from FNA shows scant nuclear atypia.


With numerous neutrophils in the background.


Summary of the clinical course.


Barium swallow study (frontal view) does not show any fistula from the apex of the pyriform recess.


Gross.


Microscopic. Appearance of papillary carcinoma of the thyroid.


Before chemotherapy. . Notes: (A) A chest X-ray shows right lower lung consolidation and pleural effusion (black arrow).


Before chemotherapy. (B) A chest CT shows a soft tissue mass measured as 98.7x87.4x82.7 mm3 in the right lower lung field (white arrow) with central necrosis and lobulated pleural effusion (white arrow head).


Before chemotherapy. (C) A chest CT shows no interstitial lung disease or lymphangitis carcinomatosis. . Abbreviation: CT, computed tomography.


3 days later following chemotherapy. . Notes: (A) A chest X-ray shows increased interstitial lung markings bilaterally; the implanted port was placed at the right subclavian vein.


3 days later following chemotherapy. (B) A chest CT shows diffuse ground glass opacity at the bilateral lung fields. . Abbreviation: CT, computed tomography.


HRCT of the lungs showing diffuse ground glass opacity and fine reticulation with sparing of the immediate subpleural lung tissue on axial and sagittal planes.


CT of the lungs at the level of carina and right inferior pulmonary vein prior to treatment with rituximab (left panel), during treatment with rituximab (middle panel), and after discontinuation of rituximab and initiation of steroid treatment.


CT brain demonstrating bitemporal decompressive craniectomy.


CT brain with VP shunt in situ and slit-ventricle with an underlying shunt malfunction.


Clinical appearance on initial presentation to the hand surgery service The patient had wasting of the ulnar innervated intrinsic muscles of the hand between the metacarpals. A; The patient also had an ulnar claw hand deformity.


Clinical appearance on initial presentation to the hand surgery service The patient had wasting of the ulnar innervated intrinsic muscles of the hand between the metacarpals. When the ulnar innervated intrinsic muscles cannot fire, there is extension at the metacarpalphalangeal (MCP) joints and flexion at both the proximal and distal interphalangeal (IP) joints in the ring and small fingers (b).


Medical image.


Lateral. Radiograph views of the left humerus show the radio-opaque implant located at the level of the proximal to mid humeral shaft, 16.5 cm proximal to the medial epicondyle.


Nexplanon removal. The location of the Nexplanon was marked using intra-operative fluoroscopy before incision (a).


Nexplanon removal. Surgical removal of the Nexplanon was then undertaken at this location (b). The ulnar nerve was just deep to the Nexplanon and the brachial artery was in close proximity. Note the location of the Nexplanon in relation to the incision used for the attempted in-office removal.


Identification and resection of ulnar nerve neuroma. An ulnar nerve neuroma in continuity was identified by fusiform swelling and fibrotic nerve (a).


Identification and resection of ulnar nerve neuroma. After resection of the traumatic neuroma, 3 undamaged deep ulnar nerve fascicles were left intact, but a 3 cm gap was left in the majority of the nerve (b).


Ulnar nerve reconstruction using cabled autologous sural nerve graft. Sural nerve autograft was harvested from the patient's leg and used to create a reversed, cabled nerve graft of matching length and diameter. It was placed into the ulnar nerve defect using a surgical microscope, 9-0 Nylon sutures, and fibrin glue.


Chest X-ray postero-anterior view - bilateral alveolar infiltrates (arrow).


Resolution of lesions in chest X-ray (arrows).


Chest X-ray film immediately after the puncture. . Note: An ~5 mm collapse of the apical portion of the right lung is observed (arrows).


Positron emission tomography/computed tomography findings. Intense fluorodeoxyglucose uptake was observed in the pericardium with a maximum standardized uptake value of 9.6.


Clinical course and main events of case. ED: Emergency department, NCU: Neuroscience care unit, NPE: Neurogenic pulmonary edema.


A non-contrast computed tomography scan demonstrates acute large hemorrhage in the cerebellar vermis and right hemispheres.


With blood in the ventricular system resulting in a mild hydrocephalus.


Chest radiograph taken 2 h after admission showed diffuse symmetric alveolar infiltrates, indicating pulmonary edema.


Repeated chest imaging confirmed bilateral ground-glass opacities and diffuse interstitial in fi ltrates (worse on the left side).


Intraoperative picture shows the PV to IVC shunt.


Intraoperative picture shows the ligated shunt.


Body composition changes during Ninjin'yoeito therapy. Body composition was assessed at the indicated time points using bioelectrical impedance. Ninjin'yoeito administration increased the body weight and muscle mass without affecting body fat percentage.


Changes in important factors of frailty and COPD during Ninjin'yoeito therapy. Ninjin'yoeito administration improved the patient's KCL, CAT, and HADS scores. The KCL comprises 25 items divided into seven categories: physical strength, nutritional status, oral function, socialization, memory, mood, and lifestyle. The CAT comprises 8 items that assess the various COPD symptoms. The HADS is used to measure the level of anxiety and depression and comprises 14 items.


Sacrococcygeal mass extending to the vulva.


Magnetic resonance imaging. The sagittal view shows a tumor involving the bladder (B) and the uterus (U).


Intraoperative findings showing the tumor involving the bladder.


Computed tomography-scan section showing upper right lobe and medium lobe bronchiectasis.


Right buccal view at the first visit.


Left buccal view at the first visit.


Occlusal view of mandibular area at the first visit.


Preoperative periapical radiograph of tooth 36.


Right buccal view at 6 months' review.


Left buccal view at the first visit at 6 months' review.


Right buccal view after scaling.


Tooth 36 after it was restored with composite.


Pre-operative photograph (Occlusal view).


Maxillary occlusal radiograph (The arrow marks show the position of the supernumerary teeth).


Orthopantomogrampre-operative view (The arrow marks reveal the three supernumerary teeth in relation to maxillary right permanent canine and the red circles show the missing teeth. Retained maxillary second primary molars also can be noted).


Post-operative photograph (Occlusal view).


CT findings: a cystic mass compressing the anterior wall of the trachea (Arrow).


The mass was of high intensity in T2-weighted MRI images.


Bronchoscopy shows a smooth mass, causing stenosis of the trachea.


Treatment course of maggot therapy. (a) Before maggot therapy. Necrotic tissue is seen on the surface of the wound.


Treatment course of maggot therapy. (b) After one session (48 h) of treatment, the reduction of necrotic tissues is seen.


Treatment course of maggot therapy. (c) Maggots growing from second to third instar larvae.


Treatment course of maggot therapy. (d) After six sessions of treatment, debridement was conducted to the deep portion from the ulcerated base, and favourable granulation can be seen on the amputated surface.


Intra-/post-operative view. (a) Intra-operative. Additional debridement is done.


Intra-/post-operative view. (b) Three post-operative weeks. Approximately 70% of the skin graft was taken. After conducting partial simple reefing, split thickness skin graft of 20/1000 inches was used.


The clinical course of the patient. . APAP, autoimmune pulmonary alveolar proteinosis; CT, computed tomography; DLco, carbon monoxide diffusing capacity; FEV1%, forced expiratory volume 1.0 (sec) percent; MAC, Mycobacterium avium complex; PSL, prednisolone; RECAM, treatment with rifampicin, ethambutol, and clarithromycin; VA, alveolar volume; VC, percent vital capacity.


Postprocedure chest radiography.


Chest CT scan showing bilateral ranges of pulmonary edema predominating on the right side.


Macroscopic examination of the heart: areas of scarring located at the intersection between the posterior wall and the posterior third of the septum (postero-septal).


Macroscopic examination of the coronary arteries: severe atherosclerosis with acute occlusive thrombosis at the left main trunk and left anterior descendant.


Early acute myocardial infarction at the anterior third of the septum and left ventricle anterior wall: wave fibers with elongation and narrowing as an early sign of acute ischemic damage and mild edema (HE, x10).


Subacute myocardial infarction at the left ventricular free wall and septum: loose connective tissue with capillaries and inflammatory infiltrate (HE, x10).


Myocytes hypertrophy with dysmetric and dysmorphic nuclei (HE, x10).


Small intramyocardial vessels disease with media hypertrophy (Masson Trichrome 20x).


Severe atherosclerosis with acute occlusive thrombosis at the. Left main trunk (Masson Trichrome, x2).


Left anterior descendant (Masson Trichrome, x4).


(A) Computed tomography pulmonary angiography (CTPA) revealed acute bilateral PE, bilateral pleural effusion with partial dilatation of the lower lobes and multiple discrete pulmonary nodules.


(B) Doppler ultrasound examination detected evidence of deep vein thrombosis (DVT) in the right posterior tibial vein. The right posterior tibial vein was dilated, about 10.6 mm at the deepest point, with hypoechoic filling.


Computed tomography scan revealed a thrombus floating in the left pulmonary artery and branches.


With a bilateral femoral vein thrombosis.


Digital subtraction angiography (DSA) showed inferior vena caval filters were implanted in the inferior vena at L2 level with luminal patency (C).


Emergency computed tomography (CT) scan showed cerebral infarction (D).


H & E (x 400) shows accumulated brown pigment in proximal tubular cytoplasm consistent with bile.


H & E (x 400) shows a distal tubule with a bile cast.


Creatinine and bilirubin trends.


Chest CT before treatment, showing a lesion inside the left bronchial system.


Endobronchial lipoma obstructing segment 6 of the left lower lobe bronchus on bronchoscopy.


Computed tomography chest before bronchoscopy demonstrating widespread airspace disease in the lower lobes bilaterally without volume loss, air bronchograms, or cavitation.


Computed tomography chest showing cavitation in the right lower lobe with an air-fluid level that measures 2.6 cm x 3.2 cm, highly suggestive of lung abscess.


Presence of air at the level of the cerebellum, and ,interpeduncular, and ,crural cisternsa.


Partial disruption of the posterior mastoid cells with left mastoid occupation, associated with a retrosigmoid bone defect.


Graph showing all serial measurements in our patient throughout the hospitalization.


A; PET-CT scan revealing the presence of a 7-cm left lung neoformation with no nodal involvement.


Chest CT-scan showing the presence of extensive pulmonary infarction in the residual parenchyma.


A flexible bronchoscopy showing a 4-mm bronchopleural fistula.


Chest CT scan revealing a non-homogeneous increase in density, diffuse GGO and consolidations at the right lung.


An almost complete recovery revealed by a new chest CT scan.


Bronchoscopy still image showing a gelatinous hydatid membrane.


Hydatid cyst membrane in sheath.


Transoral examination of the oropharynx showing an extensive bulging of the lateral pharyngeal wall (white star).


Sagittal.


Coronal. MRI sections (T1-sequences) of the upper airways. The images show a homogenous parapharyngeal mass adjacent to the masticator space laterally, extending to the retropharyngeal and carotid space dorsally. The mass is narrowing the upper airways at the level of the oropharynx. There are no signs of malignancy.


(C) Resected specimen of the well-defined and encapsulated (histologically confirmed) lipoma.


A: Bilateral, peripheral, ground-glass opacities diffusely involving the lungs, consistent with the diagnosis of moderate COVID-19 pneumonia.


B: Arrow points to a large adherent thrombus on the anterior wall of the ascending thoracic aorta.


C: Arrow points to a superior pole splenic infarction.


D: Arrow points to a large infarct in the posterior cortex of the left kidney.


E: Arrow points to a small infarct in the posterior cortex of the right kidney.


Fiber optic bronchoscopy revealing chest tube penetrating the bronchus intermedius; Yellow arrow demonstrating the point of entry of the chest tube into the right bronchus intermedius, at the origin of the middle and lower right lobe. (Black arrow).


Chest tube penetrating the major fissure of the right side of the original middle lobe bronchus.


Post bilobectomy chest x-ray.


Chest computed tomography (CT) with intravenous contrast demonstrating malignant left pleural effusion with left lower lobe collapse and segmental atelectasis in left upper lobe.


Chest X-ray post placement of left hemithorax pigtail catheter with drainage and significant decrease in large left pleural effusion.


A cell block preparation of pleural fluid shows a prominent plasma cell concentration by hematoxylin and eosin staining.


Numerous atypical plasma cells with increased mitotic activity by Diff Quik air-dried stained slide.


The CD138 immunostain highlights numerous clonal atypical plasma cells.


The kappa in situ hybridization stained slide shows that a majority of the CD138 plasma cells are positive for kappa light chains.


Superselective embolization with a microcatheter. (a) Selective arteriogram of the right bronchial artery shows hypervascularity in right middle zone with enlarged arteries and a small aneurysm (arrow).


Superselective embolization with a microcatheter. (b) After embolization with PVA particles, the hypervascular area and the aneurysm are not visualized.


Computed tomography angiogram showed pulmonary emboli in the right upper lobe pulmonary arteries.


Computed tomography angiogram which showed a pulmonary embolus involving the segmental branch of the left upper lobe pulmonary artery.


Biventricular thrombus.


Thrombus in patent foramen ovale (PFO).


Thrombus in descending aorta.


(a) Shows intraoperative image of craniectomy with good margins (large arrows). There is no involvement of the dura mater (thin arrow).


(b) Shows the resected cranial defect.


Evolution of peripheral lymphocytes populations. Immunomodulatory effect of rituximab on cellular compartment. Pleiotropic influence of low (150 mg/m2) rituximab dose. Data expressed as absolute numbers per mul. The cell counts were analyzed during LIP exacerbation - multiorgan lymphoproliferative disease development. Typical low level of invariant natural killer T (NKT), natural killer (NK), and regulatory T cells (Treg) was observed. After rituximab therapy abnormal innate immunity - absolute number of NK and NKT cells increased, but gradual decrease of FoxP3+ regulatory T cells was observed with increase activated CD38+T cells (not shown). Leukocyte counts analyses were done by the Sysmex Automated Hematology System. Flow cytometry was performed using a FACS Calibur flow cytometer (Becton Dickinson) and a count of lymphocyte subset was calculated by the frequency multiply the lymphocyte counts.


Atrial arrhythmias during vasodilator stress. Electrocardiogram tracings obtained at baseline (panel a), during atrial flutter.


Atrial arrhythmias during vasodilator stress.fast atrial fibrillation (2 min after aminophylline,. Left bundle branch block morphology with no R-wave progression through chest leads denoted counterclockwise rotation of the heart in horizontal plane.


Photomicrograph showing first instar larva of Oestrus ovis (x150).


Contrast-enhanced magnetic resonance image showing fungal rhinosinusitis, along with proptosis of the right eye.


Angiographic image of this patient. (A) (AP + CRA30 ) the left anterior descending branch.


Angiographic image of this patient. (B) (RAO30. + CAU20 ) the circumflex branch.


Angiographic image of this patient. (C) (AP + CRA20 ) the right coronary artery.


Computed tomography scan of thorax demonstrating a right hilar mass (red arrow).


Thoracic computed tomography showing pneumothorax.


Chest CT showing large right pneumothorax with collapsed lung and pneumomediastinum.


Preoperative CT showed fourth ventricular hemorrhage and a hyperdense mass in the cisterna magna.


Postoperative gadolinium-enhanced MRI showed no residual tumor.


(a) Preoperative chest radiograph showing bilateral extensive reticulonodular opacities obscuring cardiac borders.


(b) Preoperative high-resolution computed tomography scan of the chest showing bilateral intra and interlobular septal thickening, patchy areas of consolidation, ground glass opacities, and presence of variable-sized cysts.


Optic disc centred both eye fundus pictures. A; Right eye:note the dilated tortuous veins, retinal hemorrhages, optic disc edema, and cotton wool spots around the disc.


Optic disc centred both eye fundus pictures. B; Left eye:normal fundus.


Twelve-lead electrocardiogram showing complete left bundle branch block.


Four-chamber echocardiogram showing a dilated left ventricle.


The constantly deficient secretion of cortisol.


Contrast-enhanced computed tomography revealing atrophic bilateral adrenal glands (red arrows).


Algorithm for CTEPH Post Cardiopulmonary Bypass Management.


Massive pneumothorax.


Computerized tomography chest - mass in the left hemithorax.


Biopsy specimen showing solid blastemal cells.


The echocardiography showed a normal left ventricle ejection fraction, no vegetations were found on the heart valves and a mild right ventricle enlargement with a 21 cm x 2 cm mass in the middle of the right ventricle.


Thoracic spiral computed tomographic was performed, and thrombus was shown in the right pulmonary artery and pulmonary embolism was confirmed.


Three months later, the right ventricular thrombus and pulmonary hypertension had disappeared on transthoracic echocardiography.


(a and b) Computed tomography of the thorax demonstrated a 1.5 cm spiculated left upper lobe mass and a 1.2 cm right upper lobe nodule. Positron-emitted tomography-computed tomography confirmed a 1.3 cm left upper lobe mass with a standardized uptake value of 4.2 and a mildly avid right upper lobe nodule.


(a and b) Follow-up computed tomography of the thorax and positron emitted tomography-computed tomography post-left upper lobectomy demonstrated only a 12 mm focus of residual linear scarring and faint fluorodeoxyglucose avidity at the site of the previous right upper lobe nodule.


Preoperative MRI with tetraventricular hydrocephalus. Note the marked dilatation of the fourth ventricle with ventral displacement of the brainstem and dorsal displacement of the cerebellum with ballooning of the foramina of Luschka and Magendie. (a) CISS.


Preoperative MRI with tetraventricular hydrocephalus. Note the marked dilatation of the fourth ventricle with ventral displacement of the brainstem and dorsal displacement of the cerebellum with ballooning of the foramina of Luschka and Magendie. (b and c) HASTE.


(a and b) Fluoroscopic dynamic cisternography demonstrating dilatation of the lateral and third ventricles with adequate flow through the foramina of Monro and cerebral aqueduct; however, a paucity of outflow is appreciated from the fourth ventricle through either foramina of Luschka or Magendie. The black arrow denotes the tip of the external ventricular drain catheter.


(a) Initial suboccipital craniectomy exposure of the cerebellar tonsils (black asterisk) and dense, adherent arachnoid within the cistern magna (white arrow).


(b) Visualization of a thick, dense, and opaque arachnoid web (black arrow) found to be obstructing the foramen of Magendie.


(c) Restoration of normal cerebrospinal fluid flow through a patent foramen of Magendie after circumferential excision of the arachnoid web.


Postoperative magnetic resonance imaging with a significant decrease in the size of the ventricular system, including the fourth ventricle, and resolution of brainstem and cerebellar displacement. (a) CISS.


Postoperative magnetic resonance imaging with a significant decrease in the size of the ventricular system, including the fourth ventricle, and resolution of brainstem and cerebellar displacement. (b and c) HASTE.


An overnight summary view of polysomnography of the case shows respiratory events, arousals, desaturation events, arterial oxygen saturation, and sleep stages. The sleep study revealed an AHI score of 84.3 and lowest oxygen saturation of 70%, which is consistent with a diagnosis of severe obstructive sleep apnea with desaturation. SaO2 = arterial oxygen saturation, AHI = apnea hypopnea index, Mvt = movement, W = waking state R = rapid eye movement sleep, and N1, N2, and N3 = non-REM sleep stages.


The trend of patient's creatinine from admission to discharge.


Chest computed tomography showed bilateral bronchiectasis in the lower lung zones and marked emphysema with lower lobe nodular infiltrates.


A-c Tumoral calcinosis. A; Lesion consisting of an area of basophilic calcified material with surrounding reactive giant cells. Hematoxylin and eosin. X100.


B, c Giant cells in high-power magnification. Hematoxylin and eosin. X200.


Middle suboccipital craniectomy (a). Even though the MRI showed severe edema, the cerebellum was displaced dorsally away from the dural edge (a).


During the endoscopic third ventriculostomy, we observed midbrain microhemorrhages and an active flow through the tuber cinereum fenestration (b and c).


The patient was engaged in shaving ring-shaped aluminum material, such as the upper 2 images, and making camera parts, like the one below.


With a curving machine Workers are required to pour cutting oil on the material while cutting, as in (b), but our patient failed to do so, suggesting he might have inhaled a larger amount of aluminum-containing fumes than other worker in this occupation.


Chest X-ray showing bilateral pleural thickening in the upper and middle lung fields. The lung volume was reduced and reticulonodular shadows extended from the sub-pleura to deep inside the lungs, suggesting pulmonary fibrosis. The tracheal bifurcation was widened by traction of the upper lobes.


High-resolution computed tomography showing severe bilateral pleural thickening with shrunken and distorted upper lobes (a, c). There was mediastinal emphysema (a).


On the other hand, reticulonodular shadows and bronchiectasis were distributed deep inside the lower lung (b, c).


High-resolution computed tomography showing severe bilateral pleural thickening with shrunken and distorted upper lobes (a, c). On the other hand, reticulonodular shadows and bronchiectasis were distributed deep inside the lower lung (b, c).


Elemental analysis of the biopsy specimen by electron probe X-ray microanalysis (EPMA). Aluminum was identified in a fragment of bronchial wall obtained by trans-bronchial lung biopsy (TBLB), after staining with hematoxylin and eosin (a). Deposition of elements in the specimen was shown by red to yellow colours. The green colour indicated deposition of nitrogen as a control.


Elemental analysis of the biopsy specimen by electron probe X-ray microanalysis (EPMA). Significant amounts of aluminum were identified by EPMA as shown by red to yellow colours.


Elemental analysis of the biopsy specimen by electron probe X-ray microanalysis (EPMA). , whereas iron and silica were detected in much lower amounts compared with aluminum.


Clinical, therapeutic, and radiological course. Abbreviations: CSF cerebrospinal fluid; d, days; EEG, electroencephalography; GE, gadolinium-enhancement; IVIG, intravenous immunoglobulin; JCV-PCR John Cunningham virus-polymerase chain reaction; MP, methylprednisolone; MRI, magnetic resonance imaging; NCSE, non-convulsive status epilepticus.


Neuroimaging. Brain CT in the postoperative course after the patient developed nausea, vomiting, and generalized weakness. The red arrows point at revealing wide-spread bilateral hypodensities in the subcortical white matter of the frontal, parietal, and occipital lobe (A,B). Brain MRI findings on day 14 of month 1 of the first nivolimab course. T1-contrast enhanced images on the same level as image [ (red arrow).


Neuroimaging. Brain CT in the postoperative course after the patient developed nausea, vomiting, and generalized weakness. The red arrows point at revealing wide-spread bilateral hypodensities in the subcortical white matter of the frontal, parietal, and occipital lobe (A,B). Brain MRI findings on day 14 of month 1 of the first nivolimab course.


Neuroimaging. Brain CT in the postoperative course after the patient developed nausea, vomiting, and generalized weakness. Fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) showing multiple bilateral hyperintensities in gray cerebellar matter [(C), red arrows.


Neuroimaging. Brain CT in the postoperative course after the patient developed nausea, vomiting, and generalized weakness.


Neuroimaging. Brain CT in the postoperative course after the patient developed nausea, vomiting, and generalized weakness. MRI FLAIR images showing bilateral thalamic hyperintensities with corresponding T1-contrast enhancement left [, red arrow.


Neuroimaging. Brain CT in the postoperative course after the patient developed nausea, vomiting, and generalized weakness. FLAIR MRI images showing confluent cortical hyperintensities.


Neuroimaging. Brain CT in the postoperative course after the patient developed nausea, vomiting, and generalized weakness. T1 contrast-enhancement showing pial gyriform pattern of enhancement [, red arrows.


(a) Hematoxylin and eosin-stained section showed a cellular tumor with round nuclei, coarse chromatin, small to conspicuous nucleoli and moderate amount of eosinophilic cytoplasm.


Arrow points to a cell with tailing of the cytoplasm.


Myogenin immunohistochemistry showed diffuse strong nuclear staining. Diffuse strong cytoplasmic staining for desmin and vimentin, respectively.


Pathological findings of the cyst wall (hematoxylin and eosin stain). Bronchial gland (*), cartilage (**) with infiltration of inflammatory cells.


On clinical examination reduced mouth opening, increasing restriction in the jaw's latero- and protrusion movement, a right deviation while opening and diffuse pain in the right lower jaw had been noticed since 2 months following inferior alveolar nerve block anesthesia.


Magnetic resonance imaging-scan; a 2 cm x 1.7 cm x 2.4 cm sharp defined hypointense suspect mass of 7 mm diameter was detected lateral to the right lateral pterygoid muscle and medial to the right temporal muscle.


Dynamic reference frame fixed with screws on the patient's skull in contact with the navigation workstation ("line of sight").


Navigation workstation. The navigation probe was calibrated for intraoperative computed tomography-tracking and direct visualization on the workstation's monitor by touching the operation field.


Navigation probe (front) and reference frame fixed on the patient's skull (back).


The lesion and the surrounding capsulated structure could be excised completely as one specimen under direct visual control using the navigation system.


Pathogenic germline MEN1 variant (c.654 + 1G > T, IVS3, g.3405G > T) identified in the present MEN1 case reported with hydrocephalus and intracranial hypertension for giant prolactinoma. The change in heterozygous of the nucleotide guanine for timine at the canonic region +1 of the intron 3 of the MEN1 gene (c.654 + 1G > T; HGMD: CS982266; dbSNP: rs794728622) results in a splicing donor variant (ref. seq: ENST00000312049; NM_130799).


Chest X-ray in PA (posterior Anterior) view is normal.


99mTc DTPA (Diethylene triamine penta acetic acid) aerosol lung ventilation images.


Chest X-ray with left-sided pneumothorax and cervical subcutaneous emphysema.


(A) X-ray of neck lateral incidence. . Notes:. Neck emphysema on the anterior side (arrows).


(B) X-ray AP incidence. Neck and mediastinal emphysema (arrows). . Abbreviation: AP, anteroposterior.


Orbital CT scan. . Notes: (A) Orbital CT scan, coronal incidence. Face bilateral emphysema on the soft tissue (large arrows) and orbital and subconjunctival emphysema too (small arrows).


Orbital CT scan. (B) Image detail. Ancient orbital fracture sequela (asterisk) and silicon oil into the vitreous cavity (double asterisks). . Abbreviation: CT, computed tomography.


A 71-year-old man with a history of chronic obstructive pulmonary disease, pulmonary hypertension, and prior pulmonary tuberculosis infection presenting with progressive dyspnea, diagnosed with tuberculosis-associated fibrosing mediastinitis. Chest posteroanterior radiograph showing bilateral peri-hilar soft tissue densities (white arrows) with right apical, pleural thickening and volume loss (black arrow head).


A 71-year-old man with a history of chronic obstructive pulmonary disease, pulmonary hypertension, and prior pulmonary tuberculosis infection presenting with progressive dyspnea, diagnosed with tuberculosis-associated fibrosing mediastinitis. Contrast-enhanced chest computed tomography, soft tissue window. (a-d) Demonstrates ill-defined, infiltrative bilateral hilar soft tissue densities with calcifications (white arrows); enlargement of the main and right pulmonary artery (black arrow heads); and irregular narrowing of the right mainstem and upper lobe bronchi (black arrow).


A 71-year-old man with a history of chronic obstructive pulmonary disease, pulmonary hypertension, and prior pulmonary tuberculosis infection presenting with progressive dyspnea, diagnosed with tuberculosis-associated fibrosing mediastinitis. Noncontrast enhanced computed tomography chest, soft tissue window, from 3-years prior. (a-d) Demonstrating ill-defined, infiltrative bilateral hilar soft tissue densities with calcifications (white arrows); enlargement of the main and right pulmonary artery (black arrow heads); and irregular narrowing of the right mainstem and upper lobe bronchi (black arrow).


Urine specimen of our patient [dark brown on standing].


(a and b) Macroscopic photographs of the autopsy specimen. Both the spinal column.


(a and b) Macroscopic photographs of the autopsy specimen. Brain. Were covered with thick pus.


(c) An immunohistochemical photomicrograph showing a cluster of round cells positive for pneumococcal anti-gen, establishing a diagnosis of pneumococcal meningoencephalitis (Original magnification: x100).


Extraoral photograph showing diffuse swelling and facial asymmetry over the left side of mandible.


Dental CT showed diffuse increase through out of the lesion of mandible.


Incisional biopsy for histopathological examination.


3D Reconstruction of the mandible showing perforation.


Extraoral photograph; comparison before and after surgery.


Postoperative T2-weighted image after left thalamotomy with anatomical mapping by Brainlab Elements. The arrow shows coagulated lesions in the left ventro-oral (Vo) nucleus. Posterior coagulated lesions are located in the ventral intermediate nucleus (Vim). The arrowhead shows an old lesion after previous surgery, which was confirmed in the Vo and Vim nucleus. Blue: thalamus, Pink: Vim, Green: ventral posterior lateral nucleus, Yellow: ventral posterior medial nucleus.


Axial.


Coronal. T1-weighted magnetic resonance imaging showing contrast-enhancing dural-based lesion with parenchymal invasion along the right frontal lobe (arrow).


Axial ,. Along the falx cerebri.


Coronal. Right temporal lobe.


Sagittal. T1-weighted magnetic resonance imaging showing contrast-enhancing dural-based lesions through the frontal sinus, and . Right sphenoid wing. (arrows).


Sagittal. T1-weighted magnetic resonance imaging showing a contrast-enhancing sinonasal mass with intracranial extension through the cribriform plate into the anterior cranial fossa, maxillary, and sphenoid sinuses.


Sagittal T1-weighted magnetic resonance imaging showing contrast-enhancing dural-based lesions posterior to C2 vertebral body.


Posterior to T9-T10 disc space.


Along the posterolateral dura at the L3-L4 level. (arrows).


X-ray showing hip joint state after removal of prosthesis and placement of a cement spacer.


X-ray showing osteolytic zones around the acetabular and femoral components.


X - ray showing sclerotic deformation of the distal femoral metaepiphysis.


Magnetic resonance imaging showing fluid collections in the soft tissues of the left hip region.


showed QS patter with T-wave inversion in III and a VF.


CT angiogram showing bilateral pulmonary emboli.


Coronal.


Sagittal. Images of a computed tomography (CT) of the chest obtained upon the patient's second hospital admission demonstrates development of a hepatic dome fluid collection (thick arrow) associated with air foci and a right middle lobe consolidation (thin arrow). At the time of this CT, no biliptysis had been reported.


Sagittal image of a computed tomography (CT) of the chest performed 4 days after the study in Figure 1 demonstrates development of a new right lower lobe consolidation (thin arrow). A partially visualized drain termin ates in the hepatic dome abscess. Biliptysis presented 2 days after this CT was performed.


Planar cholescintigraphy with technetium-99m mebrofenin performed 1 day after the onset of biliptysis. Images were acquired over 60 min. Radiotracer collects in the site of the hepatic abscess (thick arrow) and then extends via the fistula into the right lung (thin arrow). There is also appearance of radiotracer in the left upper abdomen likely related to bile leak.


Coronal single-photon emission computed tomography images from the same cholescintigraphy study as in Figure 3, obtained following the 60-min planar images. There is an accumulation of the radiotracer in the hepatic dome abscess (thick arrow), in the fistulous tract (thin arrow) and in the right lower lobe consolidation (curved arrow). These images more accurately identify the location of the bronchobiliary fistula.


Photograph of yellow fluid (positive for bilirubin) aspirated from the right lower lobe during bronchoalveolar lavage on the same day as the technetium-99m mebrofenin cholescintigraphy study in Figures 3 and 4.


(Lateral, and ,AP views of skull).


(axial and coronal CT) show a heavily calcified lesion in the left frontotemporal region with its origin from the temporal bone immediately behind the pterion. The mass is non-homogeneous with sharply defined margins. The arrow indicates where the lesion may have become intradural.


MR images. Are from 2014. Axial FLAIR images (a and c) demonstrate adjacent vasogenic edema extending in the left temporal lobe and optic radiation. These images reveal the extensive nature of this mass, occupying a large part of the left middle cranial fossa with resultant shift of the uncus medially deforming the suprasellar cistern and shifting the midbrain. On coronal images upward displacement of left MCA is seen.


MR images. Are from 2014.


Are from 2016, just prior to surgical resection. These demonstrate growth of this lesion over a two-year period. Axial FLAIR images (a and c) demonstrate adjacent vasogenic edema extending in the left temporal lobe and optic radiation. These images reveal the extensive nature of this mass, occupying a large part of the left middle cranial fossa with resultant shift of the uncus medially deforming the suprasellar cistern and shifting the midbrain. On coronal images upward displacement of left MCA is seen.


Are from 2016, just prior to surgical resection. These demonstrate growth of this lesion over a two-year period.


CT through middle cranial fossa shows the mass and its relations with the left petrous bone. Note close relations of the mass to the left cochlea and geniculate ganglion.


CT scan Head without Contrast.


MRI Brain without contrast.


MRA Brain.


Troponin trend.


Electrocardiogram shows normal axis and negative T-waves in leads V1-5 at presentation.


The image of the left deviated heart in two-dimensional echocardiography. The apical 4-chamber window showing the abnormal position of the apex, receding to the left (unusual long-axis parasternal view with an oblique). . LA: Left atrium; LV: Left ventricle; RA: Right atrium; RV: Right ventricle.


Chest X-ray image: Frontal projection showing heart displacement in the left sided (arrow).


Computed tomography angiography imaging and chest X-ray in a patient. (A) The chest computed tomography (CT) image shows the absence of pericardium along with the cardiac chambers (white arrows). Chest CT also reveals deviation of cardiac apex to a more lateral position and shift of heart to the left hemithorax.


Computed tomography angiography imaging and chest X-ray in a patient. (B) The chest CT reveals the interposition of the lung between the aortic arch and pulmonary trunk (white arrow). . LA: Left atrium, LV: Left ventricle, RA: Right atrium, RV: Right ventricle, Ao: Aorta, P: Pulmonary trunk.


Brain magnetic resonance imaging. Diffusion-weighted images.


Brain magnetic resonance imaging. Apparent diffusion coefficient map. Showing areas of water-free-motion restriction in the right frontal lobe, compatible with acute ischemic stroke.


The coronal non-contrast-enhanced computed tomography (CT) scan showing the presence of gas in pelvicalyceal systems of both kidneys (white arrows). CT scans were taken at admission to the hospital.


The axial non-contrast-enhanced computed tomography scan showing the presence of gas in pelvicalyceal systems of both kidneys (white arrows) and gas foci in the bladder wall. CT scans were taken at admission to the hospital.


The coronal non-contrast-enhanced computed tomography (CT) scan (The kidneys level) revealed complete regression of the imaging findings of the disease. CT scans were taken on the 27th day of hospitalization.


The coronal non-contrast-enhanced computed tomography (CT) scan (The bladder level) revealed complete regression of the imaging findings of the disease. CT scans were taken on the 27th day of hospitalization.


Transmission electron microscopy (EM) of representative nasal epithelium cilia from patients #7 with demonstration of 50% normal ciliated cells. In the remaining 50% ciliated cells axonemes lacking both dynein arms were found.


Transmission electron microscopy (EM) of representative nasal epithelium cilia from patients #8 with primary ciliary dyskinesia caused by lacking of inner dynein arms.


Transmission electron microscopy (EM) of representative nasal epithelium cilia from patient #1 with primary ciliary dyskinesia caused by demonstration of cilia lacking of inner dynein arms and ciliary abnormalities of symmetry presumably related to defects in the radial spokes.


Transmission electron microscopy (EM) of representative nasal epithelium cilia from patient #2 with primary ciliary dyskinesia caused by demonstration of cilia lacking of lacking outer dynein arm.


Transmission electron microscopy (EM) of representative nasal epithelium cilia from patient #3 with primary ciliary dyskinesia caused by demonstration of cilia lacking of lacking outer dynein arm.


CT-scan performed in patient #3 during hospitalization for pneumonia in lower left lobe.


Transmission electron microscopy (EM) of representative nasal epithelium cilia from patient #4 with primary ciliary dyskinesia caused by demonstration of cilia lacking of lacking outer dynein arms.


CT-scan performed in patient #4 during hospitalization for pneumonia in upper left lobe.


Transmission electron microscopy (EM) of representative nasal epithelium cilia from patient #5 with primary ciliary dyskinesia caused by demonstration of cilia lacking of lacking outer dynein arm.


Transmission electron microscopy (EM) of representative nasal epithelium cilia from patient #6 with demonstration of cilia with presence of both dynein arms but abnormalities in number and disposition of outer microtubular pair.


Patient #6, the cilia were asymmetric, some of them lacking of central pair. Basal bodies showed an atypical distribution.


Laryngoscopy image: The extraluminal mass distorts the normal laryngeal architecture causing narrowing of the glottis lumen (arrows) and bilateral laryngeal paralysis.


Histology image: Portion of skeletal muscle with markedly distorted architecture and mild inflammatory changes. Myofibers show severe variations in size, shape and staining affinity. Disarray of orientation is evident, with fibres in transverse, longitudinal and oblique section. Degeneration, regenerative changes and fibrosis are also evident (H&E stain, 10X).


EPN on CT of abdomen; the subcutaneous emphysema extending from the abdomen's right side involves the thorax.


Echocardiogram in apical four chamber view. Left: Severe RV and RA dilatation. Right: Mild RV and RA dilatation in recovery.


Color Doppler ultrasound imaging. a on November 3, 2017 (23 + 4 weeks of gestation), color Doppler ultrasound imaging showed a hyperechogenic mass in the fetal left ventricle, measuring 1.8 cm x 1.57 cm, broadening of the left lateral ventricle (1.11 cm) and a strong dot-like echo in the left ventricle; b on December 7, 2017, color Doppler ultrasound reexaminations displayed multiple strong echoes in the fetal left ventricle (measuring 3.3 cm x 2.03 cm), compression of the left ventricular outflow tract, obvious enlargement of the tumor, and a 0.92 cm internal diameter of posterior horn of the left lateral ventricle.


Chromosomal microarray analysis detects a 1.8 Mb-duplication of the chromosome 15q13.2q13.3 region containing 7 genes, which occurs in the region between BP4-BP5 on chromosome 15q13.3.


Chest X-ray often reveal bilateral symmetrical opacities centrally in mid and lower lung zones and sometimes reticular markings. Segmental atelectasis may occur due to obstruction. In chronic cases of PAP focal fibrosis may occur.


Photomicrographs of the transbronchial lung biopsy showed massive filling of alveolar spaces with granular material. The alveolar septae were focally thickened, but otherwise the structure was intact. There were no signs of inflammation or malignancy.


Chest radiograph showing a hemopneumothorax of the left lung.


Chest radiograph one hour after drainage of the left hemopneumothorax showing bilateral pulmonary edema.


Ultrasound image of the upper right lobe. . The dotted arrows indicate the rib shadows. The horizontal arrow indicates the pleura. Between the dotted arrows B-lines can be seen in a pattern called ground-glass rockets, showing an interstitial syndrome.


Contrast enhanced T1W coronal MRI showing a large pituitary adenoma with surasellar extension.


Contrast enhanced T1W coronal MRI showing a clinoidal meningioma.


The CT images of the adrenal glands for case1.


Case 2.


Case 3 Adrenal contrast-enhanced CT showed adrenal hyperplasia (arrows).


Hyperostotic esthesioneuroblastoma in 65-year-old male mimicking fibrous dysplasia. . A, B. Axial and coronal CT images show diffuse sclerotic expansile bones of anterior skull base and superior sinonasal cavity (arrows). Hyperostotic bones show homogeneous, ground glass appearance.


Hyperostotic esthesioneuroblastoma in 65-year-old male mimicking fibrous dysplasia. C, D. Axial T2 and post-contrast T1 fat saturated MR images show enhancing rind of soft tissue mass (curved arrows) along hyperostotic bones (dashed arrows) which shows mild heterogeneous enhancement. Note formation of small cysts at tumor-brain interface (short arrows). Note formation of mucocele (long arrow).


Hyperostotic esthesioneuroblastoma in 65-year-old male mimicking fibrous dysplasia. . E, F. Axial and coronal FDG-PET CT fused color images show intense FDG avidity in hyperostotic bones (blue arrows) indicating diffuse tumor infiltration. Uptake in thin rind of soft tissue mass could not be separately visualized.


Hyperostotic esthesioneuroblastoma in 65-year-old male mimicking fibrous dysplasia. G, H. Histologic images (H&E stains with 200 x . Shows predominantly reactive bone formation.


Hyperostotic esthesioneuroblastoma in 65-year-old male mimicking fibrous dysplasia. G, H. 400 x. Magnification). Demonstrates sheet of tumor cells (arrows) within reactive bone.


(a and b) T2-weighted Brain MRI (coronal plane). T2 Coronal MRI thin-section 3D CISS images showing the right PICA crossing the cerebello-pontine cistern in close contact with the right VII and VIII nerves. The arrow indicates the PICA loop.


(a-c) Axial MRI thin-section 3D CISS images: the right PICA makes a loop in the cerebello-pontine cistern.


(d) Close contact of the PICA and VII nerve. The arrow indicates the close contact between the vessel and the VII-VIII nerve complex.


Intraoperative views during microvascular decompression. We observed close contact between vascular structures and the facial nerve, which could explain the irritative symptoms presented by the patient. *VII-VIII nerve complex; arrow-head - loop of PICA; IX - glossopharyngeal nerve.


(a) Computed tomography, sagittal view, transverse fracture of T11, subluxation of the vertebral body.


(b) T2-weighted magnetic resonance imaging, sagittal view, injury of the posterior ligament complex.


(c) Computed axial tomography, axial view, double image of vertebral laminae due to subluxation.


Computed axial tomography Angiography, (a-c) Coronal, sagittal, and axial view (yellow circle), respectively where high density material is observed in the paravertebral venous system, is suggestive of cement embolus.


(d) Presence of the high density material occupying the lumen of the subsegmental arterial vessels, in the apicoposterior segment of both upper lobes, anterior segment of the right upper lobe, lingula lobe, middle lobe, posterior and medial basal, segment of the right lower lobe.


Follow-up at 1 week after surgery. Instrumentation with transpedicular screws at T9, T10, T12 and L1 with polymethylmethacrylate augmentation. (a) Anteroposterior view, radiopaque image in right lung associated with cement emboli.


Follow-up at 1 week after surgery. Instrumentation with transpedicular screws at T9, T10, T12 and L1 with polymethylmethacrylate augmentation. (b) sagittal view radiopaque image which is correlated with cement leakage through the paravertebral venous system.


Intralobar pulmonary sequestration. A 26-year-old woman with recurrent hemoptysis. Contrast-enhanced spiral computed tomography (CT) shows the aberrant artery (arrow) originated from thoracic aorta and introduced to lower left lobe of the lung.


Computed tomography image of the lung shows small intralobar sequestrated area as bronchiectasis (arrow) in the left lower lobe (LLL).


Aortography image reveals the aberrant arteries (arrow). The anomalous artery originates from the distal part of the thoracic aorta and supplies the blood circulation of the sequestrated lung tissue.


Operative view of the patient. Dia: Diaphragm, Ao: Aorta, Ar: Aberrant artery, IPV: Inferior pulmonary vein, LLL: Left lower lobe.


Patient's skin and teeth manifestations. . Notes:. Hyperpigmented lesions on the back, and ,abdomen.


Patient's skin and teeth manifestations. Stage 4 hypopigmented lesion on the lower limbs.


Patient's skin and teeth manifestations. Conoid and missing teeth.


Cardiac catheterization. . Notes:. Right pulmonary artery.


Cardiac catheterization. Left pulmonary artery. Black arrows point to collateral vessels; white arrows point to right and left pulmonary arteries.


axial FLAIR MRI of the patient shows slightly hyperintense mass lesion in 4th Ventricle).


Coronal section from computed tomographic pulmonary angiogram scan. A feeding arterial vessel (red arrow) arises from the lower thoracic aorta supplying an intralobar bronchopulmonary sequestration within the right lower lobe. This intralobar bronchopulmonary sequestration correlated with the mismatched perfusion defect identified on earlier single-photon emission computed tomography ventilation-perfusion imaging.


Diffuse alveolar infiltration in left lung. Right lung shows necrotic lesion in peripheral area and mild-pleural effusion.


Chest X-ray, taken at the time of admission, also shows pneumomediastinum (white arrow); the subcutaneous emphysema is also visible (black arrows).


Computed tomography scan (in the level of bifurcation) depicted an extensive subcutaneous emphysema and a huge pneumomediastinum (diameter: 10.8 cm):. Transverse.


Sagittal.


Coronal section.


The drains leading to the mediastinum via the jugular notch.


Control computed tomography scan (after 11 days of the first one) depicted a significant improvement (4.3 cm). The arrows show the mediastinal drains.


Contrast-enhanced MDCT shows. A suspicious giant pelvic AVF (arrows).


Confirmed by Color Doppler.


DSA shows branches of the left hypogastric artery sustaining the AVF.


Embolized also using Squid (arrow).


Diagnostic phlebography via trans-femoral of the right gonadal vein shows (a) multiple thrombi (arrows).


Amplatzer plug placement (arrows) via trans-jugular to occlude the right gonadal vein (b) to simultaneously reduce AVF-outflow and avoid pulmonary embolism.


Contrast-enhanced MDCT after 24 h confirms (c) the correct placement of the plug (arrows).


After the second arterial embolization performed 6 months later, the final aortography shows the complete AVF occlusion.


Chest X-ray image showing complete opacification of the left lung.


Chest computed tomography image confirming consolidation of the left lung.


Intermediate magnification micrograph of lung biopsy histology revealing lepidic growth pattern of neoplastic cells after haematoxylin and eosin staining.


Anterior Posterior view of the right arm taken in the emergency department demonstrating significant subcutaneous free air.


Lateral view of the right arm taken in the emergency department demonstrating significant subcutaneous free air.


Coronal chest computerized tomography scan demonstrating subcutaneous free air throughout the chest secondary to a pneumothorax.


Axial chest computerized tomography scan demonstrating subcutaneous free air throughout the chest secondary to a pneumothorax.


Lateral view of the right arm taken eight days after initial presentation demonstrating resolution of subcutaneous free air.


Computed tomography of the chest (top panel) showing filling defects in the right pulmonary artery (top left) and right atrium (top right) suggesting thrombi. The bottom panel shows 2-D echocardiography showing 'snake-like' thrombi in the right atrium (apical and subcostal views).


39-year-old Hispanic male was examined by his primary care physician for follow-up of his hypertension. Transesophageal echocardiography image shows quadricuspid aortic valve in short axis view, cusp 1, 2, and 3 are equal in size whereas cusp 4 is the accessory cusp and is smaller in size. RVOT: Right ventricle outflow tract; LA: Left atrium; RA: Right atrium.


39-year-old Hispanic male was examined by his primary care physician for follow-up of his hypertension. Transesophageal echocardiography with color flow in long axis view shows aortic regurgitation.


The patient's neck radiograph showing left-sided subcutaneous emphysema overlying the jaw and neck (white arrows).


Coronal computed tomography image of patient's neck showing extensive subcutaneous emphysema tracking toward the mediastinum (white arrows).


A 63-year-old woman without significant medical history who presented with subacute onset of dyspnea on exertion. (a) Computed tomography pulmonary angiogram highlights the pulmonary arteries; there is a note of a nonspecific infrahilar mass (white arrow).


A 63-year-old woman without significant medical history who presented with subacute onset of dyspnea on exertion. (b) Repeat computed tomography arteriogram allows tracing of bronchial artery (black arrows). Previously noted infrahilar mass is highlighted suggesting bronchial artery aneurysm.


A 63-year-old woman without significant medical history who presented with subacute onset of dyspnea on exertion. (a) Bronchial artery angiogram with contrast injected directly into the bronchial artery under video fluoroscopy shows contrast filling of the bronchial artery aneurysm (black arrow) and simultaneous filling of the pulmonary artery (white arrow). On video fluoroscopy, contrast was noted to flow outward toward the lung periphery.


A 63-year-old woman without significant medical history who presented with subacute onset of dyspnea on exertion. (b) Bronchial artery angiogram after slight time delay shows contrast fading from pulmonary artery (white arrow) and flowing inward toward the hila through pulmonary vein (black arrow). This was, therefore, consistent with bronchial artery to pulmonary artery fistula rather than bronchial artery to pulmonary artery fistula.


A 63-year-old woman without significant medical history who presented with subacute onset of dyspnea on exertion. Successful postembolization bronchial artery angiogram shows cyanoacrylate glue outlining and occluding the distal bronchial artery (black arrow).


CT scan of the abdomen in coronal view showing an extensive area with gas within the right lobe of the liver.


CT scan of the abdomen with contrast in axial view showing two areas with gas within the right lobe of the liver.


PEF level of the patient. The upper and lower bounds of the line represent the range of PEF change during the OPD follow-up period, and the square mark in the middle of the line represents the average maximum and minimum values of PEF during the period. Triangle marks represent the maximum PEF during the period on 2017/03/31, 2018/08/29, 2018/10/24. 2017/05/-2017/08 omalizumab use; 2017/09-2017/10 omalizumab desensitization; 2017/12/18 upper airway infection; 2018/05/07 LLL pneumonia; 2018/07/24 resume omalizumab use. PEF peak expiratory flow.


CT of the lungs demonstrates diffuse ground-glass attenuation, bilateral effusions, and scattered pulmonary nodules. The yellow arrows show prominent interlobular septal thickening.


(A) Radiation field.


(B) Before administration of Camrelizumab, CT scan showed no pneumonitis manifestation.


(C) After administration of Camrelizumab, CT scan revealed patchy consolidation and ground-glass opacities localized within the previously irradiated area.


(D) Reexamination of CT showed significant improvement in pneumonitis 2 weeks after administration of prednisolone.


Computed tomography image of thorax: The nail penetrating the lung parenchyma and focal alveolar hemorrhage.


Emergency department chest X-ray showing pulmonary edema without cardiomegaly.


Facial image of patient showing blue line on gums.


Posterior-anterior (PA) chest radiograph demonstrating bilateral infiltrates consistent with eosinophilic pneumonia.


Marked mixed pulmonary pattern with diffuse radiographic lesions in a 7-month-old Miniature Poodle presented with respiratory decompensation while receiving appropriate antimicrobials. Right.


Marked mixed pulmonary pattern with diffuse radiographic lesions in a 7-month-old Miniature Poodle presented with respiratory decompensation while receiving appropriate antimicrobials. Left lateral radiographic projections showing bilateral diffuse lesions characterized by marked diffuse small airway thickening (white arrow), peribronchial cuffing and multifocal alveolar pattern (*) with air bronchograms (arrowheads). Incidentally, intra-thoracic tracheal luminal diameter (doubleheaded arrows) varied on average 28% between both lateral projections suggesting dynamic tracheal collapse. The tracheal bifurcation and principal bronchus were narrowed on the left lateral projection.


Marked mixed pulmonary pattern with diffuse radiographic lesions in a 7-month-old Miniature Poodle presented with respiratory decompensation while receiving appropriate antimicrobials. (C) On the ventrodorsal projection, the left cranial lung lobe is completely opacified (*) and the cardiac silhouette is shifted to the left (long horizontal arrow). The lesions are centered around the lobar and segmental bronchi (short arrows) and decrease in severity toward the periphery. The left caudal lung lobe (LCd; flared arrows) is the second most severely affected lobe after the left cranial lobe.


Transverse (3 mm-thick) computed tomographic (CT) images of a Miniature Poodle obtained at 9 months. Using a single slice CT).


8 years. Using a 64-detector row CT) of age displayed from the same level side by side. On the first study, the left cranial lung lobe (single opened arrow) is completely collapsed with almost complete absence of air in the airways. The caudal branch of the left cranial lobar bronchus is narrowed but filled with air (ventral to opened arrow on C). The left caudal lung lobe is also severely reduced in volume and thus, increased in attenuation with several air-filled end on airways (double arrows). The right lung is hyperinflated with the right cranial (RCr) and accessory (RAcc) lobes extending to the left of midline. Mosaic pattern characterized by a well circumscribed hypoattenuating area is seen in the accessory lobe (arrowhead). The parenchyma is otherwise relatively normal. By 8 years of age and after undergoing left cranial lobectomy as a puppy, the entire hyperinflated right lung has developed severe patchy parenchymal lesions consisting of ground-glass opacification (black arrows) and consolidation (*). This latter is most severe surrounding medium- to large-caliber dilated airways. Traction bronchiectasis (black arrowheads) in areas of architectural distortion is seen at the periphery of several of these airways, a common feature seen with pulmonary fibrosis. The mosaic pattern previously recognized in the accessory lobe (white arrowheads) is accentuated. Several cystic air-filled structures (white arrows) of varying size occupy the left caudal lobe.


Five years post left cranial lobectomy, radiographic lesions were still present especially in the left caudal lung lobe of a 6-year-old Miniature poodle. (A) Left lateral projection showing several areas of increased opacity in the cranioventral, caudoventral and caudodorsal lung field (arrows). In the caudodorsal lung field, a large bronchus (arrowhead) is dilated and does not taper as it extends toward the periphery indicating bronchiectasis. In the more severe opacified areas, small air bronchograms are seen (white arrow).


Five years post left cranial lobectomy, radiographic lesions were still present especially in the left caudal lung lobe of a 6-year-old Miniature poodle. (B) Right lateral projection revealing radiographic lesions (black and white arrows) similar to those on the left and most prominent in the caudodorsal lung field. They are less extensive in the ventral aspect of the thorax in comparison to the left lateral view. Note that some lesions maybe less distinct due to motion artifact.


Five years post left cranial lobectomy, radiographic lesions were still present especially in the left caudal lung lobe of a 6-year-old Miniature poodle. (C) As expected following left cranial lobectomy, leftward mediastinal shift remains visible (black arrow) on the ventrodorsal projection. The borders of the left caudal lobe appear retracted (arrowhead) and the lung lobe is increased in opacity. Lesions are most severe centrally and less extensive toward the periphery. Similarly, radiographic opacity is increased (white arrows) surrounding major lobar structures (vessels and bronchus) of the right lung and gradually diminish in periphery of the lung.


Chest computed tomography, showing perihilar consolidations at both sides with underlying bronchiectasis. In the periphery of the lungs smaller nodular infiltrates are visible. These are indicated by the arrows.


Microscopy after kinyoun staining of
M. microti
 in culture. This culture became positive after 75 days of incubation. The microscope used was a Zeiss Axioskop, the magnification x100.


Computed tomography of the left hip, showing bone destruction of the anterior side of the collum. Next to this site, multiple fluid collections are visible, which are highly suspicious for abscesses. These collections infiltrate in the adjacent muscles. The largest collection in this view measures 64.5 by 37.1 mm and has a very thick wall.


Intraoperative changes of hemodynamic parameters. Changes in CVP (black line) and SVV (gray line). High and low lines show systolic and diastolic blood pressure. CVP = central venous pressure, SVV = stroke volume variation, CI = cardiac index, HR = heart rate, ABP = arterial blood pressure, Ht = hematocrit.


FT-IR analysis of the lung tissue of the patient shows the presence of PTFE compared with the standard PTFE peak result.


A; Thermogravimetric analysis of the patient's personal air sample shows prominent weight loss at 550-660. C. A total of 0.40994 mg of the sample weight was reduced at 550-600. C.


B; Thermogravimetric analysis of the regional sample shows weight loss near 450. C, and no prominent weight loss was found at 550-600. C.


C; Thermogravimetric analysis of the PTFE spray solution shows prominent weight loss at 550-600. C.


Continuous video-electroencephalography monitoring during her third attack showing that the patient was asleep.


Repeated electroencephalography demonstrated randomly occurring generalized epileptic discharges with the photic sensitivity after her last attack ceased.


In a 13-months old girls, bilateral severe pulmonary dystelectasis, revealed by post-mortem examination.


Correspond to the Rx-image, which shows ground-glass opacities, in the right lung, and diffuse opacity of the left lung.


Microscopic and immunohistochemical features of desquamative interstitial pneumonia:. Hemorrhages, and ,thrombi (arrow).


Bronchiolar damage.


Desquamated pneumocytes, with syncytial-like bodies.


Scanty T-cells.


Necrosis of the desquamated cells, with genesis of membranes.


Encasement of alveolar septa by cytokeratin-positive membranes.


Positivity of the desquamated cells for cytokeratin.


IgA positivity in the desquamated cells.


Gross findings of kidneys. Bilateral enlargement, with hyperaemic surface of the left kidney.


Gross findings of kidneys. Passive hyperemia of the cortex.


Gross findings of kidneys. Passive hyperemia of the cortex. Parenchymatous congestion, with interstitial edema.


Gross findings of kidneys. Parenchymatous congestion, with interstitial edema.


Proliferative glomerulonephritis. In Hematoxylin-Eosin, microscopic features consist on mesangium enlargement and proliferation of podocytes (A-C).


Proliferative glomerulonephritis. Immunohistochemically, the proliferated podocytes are marked by WT1.


Proliferative glomerulonephritis. And surround the CD31-positive capillaries.


Proliferative glomerulonephritis. , without positivity for CD44.


Two years after resection of the large mass in basal aspect of right hemithorax, there are numerous bilateral parenchymal and pleural-based nodules and masses with maximum size of 42 x 40 mm c, d.


(A) ANA aspect of Case #1. IIF on Hep-2 (1/80) revealed presence of rare isolated cytoplasmic islets (1), homogenous staining (2), multiple nuclear dots pattern (3) and anti-Golgi apparatus pattern (4).


(B) Radiographic imaging of Case #2. Thoracic computed tomography scan revealed bilateral interstitial lung disease with lower lung predominance, thickened alveolar septa, condensations, and traction bronchiectasis.


Biological follow-up and treatment of Case #2. The full curve represents the regression of anti-MDA5 antibodies titers (expressed as relative intensity) and the dotted curve the evolution of serum ferritin level. Five plasma exchanges were performed (arrows), preceded and followed by cyclophosphamide infusions (depicted with stars). MDA5, melanoma differentiation-associated gene 5.


Preoperative stone burden.


Poor intraoperative observation.


Pre-operative intra-oral photograph showing missing teeth, root stumps and poor oral hygiene of the patient in the case report.


Severely atrophied alveolar ridge and partial anodontia of the patient in the case report.


Orthopantomogram showing horizontally impacted third molars and reduced bone density with severe bone atrophy in both maxilla and mandible of the patient in the case report.


Lateral cephalogram showing prognathic relation of the mandibular to the maxilla of the patient in the case report.


Upper gastrointestinal endoscopy images immediately after hematemesis. A; A longitudinal extension of reddish or wine-colored mucosal thickening (asterisk), obstructing the esophagus, is seen from the midesophagus to the esophagogastric junction.


Upper gastrointestinal endoscopy images immediately after hematemesis. B; The submucosal hematoma (two asterisks) is displacing the esophageal mucosa (asterisk) toward the gastric cavity at the esophagogastric junction. A part of the displaced mucosa has a laceration with bleeding.


Upper gastrointestinal endoscopy image 7 days after surgery. The esophageal submucosal had almost disappeared, and the slough had adhered to the mucosal laceration at the esophagogastric junction.


Preoperative Surgical Plan. . Preoperative surgical plan showing the swelling in the anterior area of the mandible, causing buccal and lingual bone expansion and displacement of the incisors.


Gross examination of the incisional biopsy. . Gross examination of the incisional biopsy revealed two firm pieces of 2.5x2x1.2 cm in size; they were reddish white in color and solid in consistency.


Photomicrograph of old incisional biopsy. . (
a) Photomicrograph of old incisional biopsy showing heavily scattered multinucleated giant cells (short arrow) in a background of highly cellular fibrous stroma consisting of mononuclear stromal cells (long arrow) and extravasated red blood cells (original magnification 40x).


Photomicrograph of old incisional biopsy. (
b) Newly formed bone trabeculae and osteoid tissue (star) were noted at the periphery of the lesion (original magnification 40x).


Computed tomography (CT) of the lesion. . (
a) CT of the lesion showing a well-defined multilocular radiolucency with diffuse flecks of radiopacities, extending from the right impacted third molar area to the left first molar area.


Computed tomography (CT) of the lesion. (
b) CT of the lesion showing perforations in the buccal and lingual cortical plates.


Gross examination of the excised lesion. . Gross examination of the excised lesion showing numerous, reddish, hard and soft pieces of tissue that ranged in size, having the average of 2x2x1.5 cm.


Photomicrograph of the excisional biopsy. . (
a) Photomicrograph of the excisional biopsy revealed extensive areas of cell-rich connective tissue stroma containing bands of osteoid matrix and anastomosing immature bone trabeculae (long arrows) (original magnification 40x).


Photomicrograph of the excisional biopsy. (
b) Scattered clusters of multinucleated giant cells (short arrows) (original magnification 40x).


Photomicrograph of the excisional biopsy. (
c) Plump osteoblasts can be seen surrounding the interconnecting immature bony trabeculae. Cellular osteoid (star) and some myxomatous areas (polygon) can also be detected (H&E stain, magnification 100x).


Chest CT images before . A; Lesions of the right lung before the initiation of erlotinib treatment.


After. Erlotinib treatment, and . B; Partial remission of lower lobe lesions of the right lung 1 month after the initiation of erlotinib treatment.


Before . C; Relapse of lower lobe lesions of the right lung with pachy shadows 4 months after the initiation of erlotinib.


After. The addition of sorafenib. D; Great mass in the lower lobe of the right lung with atelectasis, obstructive pneumonia and multiple patchy ground-glass opacities in the left lung 41 days after the addition of sorafenib.


The chest CT of patient one. (A-D): chest CT showing the nodes in the lungs and the local grid change in the right lower lobe.


The chest CT of patient one. (E-H): chest CT showing the pneumonitis 74 days after afatinib therapy, the pneumonitis manifested subpleural reticular shadow, ground glass and consolidation, and beehives, distributed in both lower lobe of both lungs. CT: computed tomography.


The episodes occurred in case 1.


The episodes occurred in case 2.


A 71-year-old man with right upper lobe T3N1M0 squamous cell carcinoma. (a) Axial computed tomography images in lung and soft-tissue windows showing an obstructive right hilar mass lesion with an endobronchial component at the origin of the right upper lobe bronchus (arrow).


A 71-year-old man with right upper lobe T3N1M0 squamous cell carcinoma. (b and c) Axial and coronal positron emission tomography/computed tomography images showing avid F-18 fluorodeoxyglucose uptake with the mass (arrow).


(a and b) Chest X-ray and coronal computed tomography reformation demonstrating the right pectoralis muscle flap (*) and Clagett window (arrow).


(c and d) Axial computed tomography images again showing the right pectoralis muscle flap (*) and Clagett window.


Bronchopleural fistula in a 71-year-old man after right pneumonectomy and Clagett window. (a and b) Axial computed tomography images in lung window demonstrating a fistula between the bronchial stump and pneumonectomy space with herniation of dressing material from the right pneumonectomy space through a fistula into the trachea and left mainstem bronchus (arrow).


High-resolution CT scan showing lung fibrosis.


O. P. G. Revealing bone loss from the alveolar ridge on the right side.


Excised specimen.


Post operative healing after 7 days.


Photomicrograph.


Intra oral growth.


Extra oral view.


Initial CT findings of left frontoparietal extra-axial hyperdensity and accompanying left-to-right shift of the ventricular system representing an acute SDH and its resultant mass effect.


With subsequent progression.


Following craniotomy and bone flap replacement there is recurrence (c).


After reoperation for craniectomy, ventricles assume a more midline position (d).


2 months postoperatively, the brain has a sunken appearance and residual postoperative fluid has disappeared (e).


Following cranioplasty the brain assumes its normal appearance (f).


A coronary angiogram demonstrating no signs of coronary atherosclerotic heart disease.


(A-C) Immunohistochemical staining CD45-positive showing peribronchial and intrabronchial wall leukocyte infiltrates.


Bone marrow eosinophilia. A representative Wright-Giemsa stain, (x400) of bone marrow aspirate smears from case 1. Notice the presence of various immature eosinophils, including eosinophilic band and Polymorphonuclear eosinophils.


Bone marrow eosinophilia. A representative Wright-Giemsa stain, (x400) of bone marrow aspirate smears from case 1. , as well as eosinophilic myelocyte and eosinophilic metamyelocyte.


The clinical course of case 1. The X axis indicate the time (days). AZA, azacitidine; WBC, white blood cells; PLS, prednisolone.


The clinical course of case 2. The X axis indicate the time (days). WBC, white blood cells; PLS, prednisolone.


Representative images of periodic acid methenamine silver staining (high magnification) of renal specimen from patient 2 showing duplication of the capillary wall consistent with membranoproliferative glomerulonephritis.


Platelet counts and treatment timeline.


Frontal view of fluoroscopic images during inguinal injection of Lipiodol. At abdominal level there is opacification of lymph vessels with drainage of Lipiodol into the cysterna chyli and thoracic duct (TD). Image of occlusion of the TD on the passage from abdominal to thoracic level. Black arrow: droplets of ethiodized oil at the passage from the inferior caval vein to the TCPC conduit, revealing early lymphovenous shunting. At thoracic level there is drainage of Lipiodol through multiple collaterals to hilar, peribronchial, mediastinal, and axillar dilated lymph vessels. Right mediastinum is more affected than the left.


Cone-beam computed tomography image during Lipiodol-based lymphangiography shows filling of several mediastinal abnormal dilated lymph vessels, predominantly peribronchial right (yellow arrows). This is similar to the fluoroscopic image of Figure 1.


Chest radiograph at presentation.


Computed tomography chest scan (axial view).


Chest radiograph on day 8 post right thoracotomy.


Repeat computed tomography chest scan showing intact splenic cyst and left effusion.


Chest radiograph 2 months post bilateral thoracotomy.


Timeline of the case after admission. (A-C) Time course of CK, myoglobin, plasma creatinine, and levels of uPCR and uACR.


Timeline of the case after admission. (D) Time of treatment regimens and kidney biopsy. CK, creatinine kinase; CYC, cyclophosphamide; uACR, urinary albumin-to-creatinine ratio; uPCR, urinary protein-to-creatinine ratio.


Histopathological findings in a kidney biopsy confirming pauci-immune crescentic GN. Representative photomicrographs of the kidney biopsy including staining for IgA (scale bar: 50 mum), IgG (scale bar: 50 mum), IgM (scale bar: 50 mum), C1q (scale bar: 50 mum), and C3c (scale bar: 50 mum); periodic acid-Schiff staining showing a glomerulus with crescent formation (scale bar: 50 mum); and hematoxylin/eosin staining with myoglobin casts (asterisks, scale bar: 100 mum) and tubulointerstitial inflammation with prominent eosinophilic infiltration (scale bar: 100 mum). C1q, complement component 1q; C3c, complement factor 3 conversion product; IgA, immunoglobulin A; IgG, immunoglobulin G; IgM, immunoglobulin M; GN, glomerulonephritis.


Right eye shows conjunctival injection, corneal edema with infiltrates at the superior corneal incision site, membrane formation around the IOL and a 2 mm hypopyon. . Abbreviation: IOL, intraocular lens.


B-scan ultrasound of the right eye shows a significant amount of vitreous debris.


Intraoperative view during vitrectomy. . Notes: (A) Vitreous opacities and exudative membranes (red arrow) were removed by vitreous cutter.


Intraoperative view during vitrectomy. (B) Retinal hemorrhages were found in all quadrants.


Wide-field fundus photography of the right eye postoperatively demonstrates an attached retina under silicone oil tamponade and full panretinal photocoagulation treatment to all quadrants.


Chest radiography findings. Chest X-rays at 2 months before The chest radiograph was normal at 2 months before admission (A).


Chest radiography findings. And at admission The chest radiograph on admission (B) demonstrates symmetric multifocal consolidation and reticulonodular opacities in both lungs.


Chest radiography findings. Lung window . Axial lung window image (C) shows peribronchial ground-glass opacity (GGO), reticulation and consolidation in the periphery of both lungs. There was no significant endobronchial lesion and no axillary lymph node enlargement.


Chest radiography findings. Mediastinal window. On chest computed tomography on admission.


Chest X-ray on discharge.


At 6 months after discontinuation of steroid therapy Note the improvement in multifocal consolidation and reticulonodular opacities in both lungs on the chest radiograph on hospital discharge and no clinical deterioration at 6 months after discontinuation of the steroid therapy.


Patient's family tree.


Changes in end-tidal carbon dioxide and arterial oxygen saturation of pulse oxymetry after sugammadex administration. Event: (1) intravenous injection of sugammadex, (2) extubation, (3) disappearance of end-tidal carbon dioxide (EtCO2), (4) decline of arterial oxygen saturation, (5) start of continuous positive airway pressure.


(A) A chest enhanced computed tomography, demonstrating a filling defect in the left inferior pulmonary artery.


(B) Pulmonary angiography, showing a large filling defect in the left pulmonary artery.


(A) Diffuse sheets of cytotrophoblastic and syncytiotrophoblastic cells (H&E staining, x400).


(B) Tumor cells with diffuse positive cytoplasmic immunostaining for beta human chorionic gonadotropin (x100).


(C) Tumor cells with positivity for pan cytokeratin (x40).


CT abdomen showing intramural air (yellow arrow) within the proximal-mid stomach consistent with emphysematous gastritis.


CT abdomen/coronal view showing intramural air (yellow arrow) within the proximal-mid stomach consistent with emphysematous gastritis.


Illustration of the clinical course. . Note: Subjective overall physical functions, plasma monoamine metabolite levels (HVA [dopamine metabolite] level, total MHPG [noradrenaline metabolite] level, and free MHPG), and drugs administered to the 35-year-old man with paroxysmal kinesigenic dyskinesia (CBZ, ESC, APZ, and LOF). . Abbreviations: APZ, aripiprazole; CBZ, carbamazepine; ESC, escitalopram; HVA, homovanillic acid; LOF, loflazepate; MHPG, 3-methoxy-4-hydroxyphenylglycol; fMHPG; free MHPG, tMHPG; total MHPG.


Contrast-enhanced magnetic resonance imaging, T1-weighted fat saturated coronal image shows a large isointense signal intensity mass admixed with hyperintense signal intensity.


Immunohistochemistry - CD 31 - positive staining of atypical endothelial cells.


Head computed tomography images of a 64-year-old man with asymptomatic symptom for coronavirus disease 2019. (a) Axial showing subarachnoid space dilated associated with cortical atrophy (Red arrows).


Head computed tomography images of a 64-year-old man with asymptomatic symptom for coronavirus disease 2019. (b) Choroid plexus calcification in the lateral ventricles (Red arrows).


Chest computed tomography (CT) images of a 64-year- old man with asymptomatic symptom for coronavirus disease 2019. Axial plane chest CT scans showing lymph nodes larger than 1 cm (Red arrows).


Right temporal lobe biopsy. HE staining. Magnification is x40. Mildly hypercellular and gliotic gray matter with focal reactive changes. No neoplasia is seen.


A; The tumor lesion before crizotinib administration was mainly necrotic with air-fluid level and had a diameter of about 41 mm, ilo-perihilar right.


B; After 10 days of crizotinib administration, a CT scan of the chest showed extensive bilateral ground-glass opacities throughout both lungs and a further increase in the solid lesion (excavated), which measured about 60 mm.


C; After treatment with corticosteroid, a reduction of the ground-glass component occurred bilaterally, while the lesion in the right lower lobe appeared essentially unchanged in morphology and size.


Diffuse invasive aspergillosis observed in autopsy lung tissue (HE x400).


Cardiomegaly with dilated pulmonary arteries. Peripheral pruning of the lung fields also seen.


Tricuspid regurgitation of severe PH.


34-year-old woman with intermittent right flank pain diagnosed with genitourinary tuberculosis. Computed tomography (CT) shows heterogeneous enhancing mass involving the upper, and ,mid pole of the right kidney with aortocaval, and ,paracaval lymphadenopathy(arrow).


34-year-old woman with intermittent right flank pain diagnosed with genitourinary tuberculosis. Contrast enhanced CT scan of the abdomen show presence of rim enhancement with central necrosis in lymph nodes (arrow).


34-year-old woman with intermittent right flank pain diagnosed with genitourinary tuberculosis. Section removed during right side nephrectomy shows normal looking kidney (thin arrow and renal mass with pus around it (thick arrow).


34-year-old woman with intermittent right flank pain diagnosed with genitourinary tuberculosis. Histopathology slides. Stained with hematoxylin, and ,eosin (x100) shows presence of multiple granulomas (thick arrow).


34-year-old woman with intermittent right flank pain diagnosed with genitourinary tuberculosis. Stained with Ziehl-Neelsen stain (x100) shows presence of acid-fast bacilli (thin arrow).


(a) Computed tomography scan showing a mass suggestive of tumor near the sellar region.


(b) Magnetic resonance angiogram showing a large aneurysm of the left internal carotid artery (ICA).


(c) T2-weighted magnetic resonance image revealing the aneurysm extending to the suprasellar region.


(d) Cerebral digital subtraction angiogram of the left ICA revealing a giant aneurysm at the cavernous portion extending in the medial direction.


Time-series graphs of hormone load tests. Luteinizing hormone (LH)-releasing hormone load test: after intravenous injection of LH-releasing hormone (0.1 mg), LH and follicle-stimulating hormone (FSH) levels were examined. Thyrotropin-releasing hormone load test: after intravenous injection of thyrotropin-releasing hormone (0.5 mg), thyroid-stimulating hormone (TSH) and prolactin (PRL) levels were examined. Corticotropin-releasing hormone load test: after intravenous injection of corticotropin-releasing hormone (0.1 mg), adrenocorticotrophic hormone (ACTH) and cortisol levels were examined. Growth hormone (GH)-releasing factor load test: after intravenous injection of GH-releasing factor (0.1 mg), GH level was examined. Solid, dotted, and dashed lines indicate the data for preoperation, postoperation (3 weeks after operation), and 1 year after operation.


(a) Computed tomography scan on the day after the operation showing thrombosis of the aneurysm.


(b) Cerebral angiogram performed at 8 days after the operation demonstrating good patency of the bypasses and disappearance of flow to the aneurysm.


Magnetic resonance angiogram.


Image. Obtained at 8 years after the operation showing good patency of the radial artery graft and shrinkage of the aneurysm.


Generalized acne on the patient's face.


Wide purplish striae on the patient's abdomen.


Serial chest radiographs showing acute pulmonary oedema from her previous 4 admissions. Left pleural effusion with bat's wings appearance, and ,cardiomegaly.


Serial chest radiographs showing acute pulmonary oedema from her previous 4 admissions. Left pleural effusion with cardiomegaly.


Serial chest radiographs showing acute pulmonary oedema from her previous 4 admissions. Upper lobe diversion with bat's wings appearance, and ,cardiomegaly.


Serial chest radiographs showing acute pulmonary oedema from her previous 4 admissions. Left pleural effusion.


Lateral view of thoracolumbar X-ray showing the compression fracture at T9 to L1 spine with osteopenic bone.


Volumetric 3D reconstruction of the thoracolumbar spine from CT images showing compression fracture.


CT adrenal pre-contrast scan showing the right adrenal adenoma (blue arrow).


CT adrenal post-contrast scan showing the well-defined hypodense lesion at the medial limb of the right adrenal gland.


Chest radiographs obtained on day 3.


Medical image.


Computed tomography scans obtained at autopsy show that the lungs were completely infiltrated by effusion.


(A) Both lungs were massively congested.


(B) Numerous filamentous fungi are seen in the lung after Grocott staining (x400).


(A) The right pulmonary artery contained an embolus (arrow).


(B) Filamentous fungi (arrow) were detected in the embolus by Periodic acid-Schiff staining (x400).