Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MAAISINVSTVKPLGDRIFVKVSPAEEKTAGGILLPDNAQEKPQIGEVVAVGPGKRNDDGSRSELDVKVGDKVLYSKYAGTDVKLSGEDYVLLSEKDILASVA

Output: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.


Protein Function Description

Instruction: Can you provide the functional description of the following protein sequence?

Output: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.


Instruction: What is the functional description of the protein sequence?

Output: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


Instruction: Predict the general functional description of the protein sequence.

Input: MIQTESTLRVADNTGAREIQCIKVIGAGQKQYANVGDVIVGTIKEATPGGVVKRGQVVRAVIVRTKRGIKRPDGSYIRFDENACVIIDENKDPRGTRIFGPVTRELREKKYMKIISLAPEVL

Output: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MIQQESRLKVADNSGAREILVIKILGGSRVKTGNIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKHGIHRKDGSYIKFDENAAVLINNDKSPKGTRIFGPIARELRGDDFMKIVSLAPEVL

Output: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.


Instruction: Predict the functional description of the protein sequence below.

Output: Provides the (R)-glutamate required for cell wall biosynthesis.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MEAALLLAKLPEAYQIFDPLVDVLPVIPVFFLLLAFVWQAAVGFR

Output: One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.


Instruction: Predict the general functional description of the protein sequence.

Output: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).


Instruction: Can you provide the functional description of the following protein sequence?

Output: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.


Instruction: What is the functional description of the protein sequence?

Input: MSEIPGDLKFLKSHEWARIESNGRVTVGISDHAQGLLGDLVYVELPGVGDTVQVGNGAAVVESVKAASDVYSPVSGTVVEVNSALSDKPETINEDAYGEGWIFVVEIDDKEQLNDLLDPDDYAELLEDDEH

Output: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


Instruction: Predict the functional description of the protein sequence below.

Input: MSRSIKKGPFIDDHLMKKTLKAKEGKDNRPIKTWSRRSTILPEMIGFTYNVHNGRVFVPVYITENHVGYKLGEFAPTRTFKGHKGSVQKKIGK

Output: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MKQGIHPEYHTDAVVKCACGNSFTTGSVKEELKVEICSKCHPFFTGKQKIVDVGGRVEKFNKRFNLDTK

Output: Binds the 23S rRNA.


Instruction: What is the functional description of the protein sequence?

Input: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKSTVIALREIEEGLITNQILDVRDRQEQHEQEAAELQAVTAIAEGRR

Output: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


Instruction: What is the functional description of the protein sequence?

Input: MPRSLKKGPFIESKLEKRIAALNSKDEKKVVKTWSRSSMIAPEFVGHTIAVHNGKSHIPVYVSENMVGHKLGEFAPTRTYRGHAGGKSEKGGSAPRKK

Output: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


Instruction: Predict the functional description of the protein sequence below.

Output: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.


Instruction: Predict the functional description of the protein sequence below.

Input: MPRSLKKGPFLDLHLLKKVEKAVESGDKKPIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSDEMIGHKLGEFAPTRTYRGHAADKKAKK

Output: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Acts as a chaperone.


Instruction: What is the functional description of the protein sequence?

Input: MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKEATRATI

Output: Catalyzes the excretion of spermidine.


Instruction: What is the functional description of the protein sequence?

Input: MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK

Output: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


Instruction: Predict the general functional description of the protein sequence.

Output: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.


Instruction: What is the functional description of the protein sequence?

Input: MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARIQLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSGMTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR

Output: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.


Instruction: What is the functional description of the protein sequence?

Output: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.


Instruction: Predict the general functional description of the protein sequence.

Output: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


Instruction: Can you provide the functional description of the following protein sequence?

Output: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


Instruction: Predict the general functional description of the protein sequence.

Output: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.


Instruction: Predict the general functional description of the protein sequence.

Output: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.


Instruction: Predict the functional description of the protein sequence below.

Input: MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE

Output: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.


Instruction: What is the functional description of the protein sequence?

Input: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ

Output: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.


Instruction: Predict the general functional description of the protein sequence.

Input: MSNIPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE

Output: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


Instruction: Predict the functional description of the protein sequence below.

Output: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Specifically methylates the adenine in position 1618 of 23S rRNA.


Instruction: What is the functional description of the protein sequence?

Input: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM

Output: Produces ATP from ADP in the presence of a proton gradient across the membrane.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Transports acetate.


Instruction: Predict the functional description of the protein sequence below.

Input: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE

Output: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


Instruction: Can you provide the functional description of the following protein sequence?

Output: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.;


Instruction: Can you provide the functional description of the following protein sequence?

Input: MSLEEKVKNIIVDKLGVEPDEVVEEASFVDDLGADSLDLVELIMSMEETFDLEISDEEAEKILKVKDVIEYIKAHT

Output: Carrier of the growing fatty acid chain in fatty acid biosynthesis.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.


Instruction: What is the functional description of the protein sequence?

Output: Required for maturation of 30S ribosomal subunits.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MPTISQLVRRGRERLQVKKKAPALKESPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIPGVGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGTLDAVGVQGRKQGRSKYGAKRAS

Output: With S4 and S5 plays an important role in translational accuracy.;


Instruction: What is the functional description of the protein sequence?

Input: MNLTHYIASIENYPKEGITFRDISPLMADGKAYSYAIREICQYAADKEIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVVSADYEKEYGLDTLTMHSDAIKPGQRVLIVDDLLATGGTVKATIEMVEKLGGVVAGCAFLIELDGLNGRQALGDIDYKVLMNFPG

Output: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


Instruction: Predict the functional description of the protein sequence below.

Input: MSRRHKAEKREINPDPKFGDLVVTKFMNAIMLHGKKSVAESIVYGAFDVVEAKSKAEPIAIFHQALENVAPHVEVRSRRVGGATYQVPVDVRPERRQALAIRWLIIAARKRNETTMVDRLSGELLDASNNRGSAVKKREDTHKMADANRAFSHYRW

Output: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.


Instruction: What is the functional description of the protein sequence?

Output: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).


Instruction: Predict the general functional description of the protein sequence.

Output: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MPNIASASKRLRQNEVRNLYNRKIKSFLNTQKKKVIKAVDSNDKNLASEEFKKYASALDKAARKSVIHANRAAAKKSDMMKKINAMN

Output: Binds directly to 16S ribosomal RNA.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MEKNYMTIPYVIEQTSRGERSYDIYSRLLKDRIIFLGGEINDDVANVVIAQLLFLESADPEKDISLYINSPGGVVTAALGMYDTMQYVKPDVATLCVGQAASAGALLLAGGAKGKRFATANSRIMIHQPSGGSRGMVTDMEIQLKETIRLKSILNNIMANHTGQDIKKLEADMDRDYFMSAEEAKDYGIIDKVFSSRE

Output: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


Instruction: Predict the general functional description of the protein sequence.

Output: Required for maturation of 30S ribosomal subunits.


Instruction: Predict the general functional description of the protein sequence.

Input: MARADKATAVADIAAQFKESTATLITEYRGLTVANLAELRRSLTGSATYAVAKNTLIKRAASEAGIEGLDELFVGPTAIAFVTGEPVDAAKAIKTFAKEHKALVIKGGYMDGHPLTVAEVERIADLESREVLLAKLAGAMKGNLAKAAGLFNAPASQLARLAAALQEKKACPGPDSAE

Output: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.


Instruction: Predict the general functional description of the protein sequence.

Output: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.


Instruction: Can you provide the functional description of the following protein sequence?

Output: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


Instruction: Predict the general functional description of the protein sequence.

Input: MSVESFTPTALQFTHGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVADDDTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI

Output: Required for insertion of 4Fe-4S clusters for at least IspG.


Instruction: Predict the general functional description of the protein sequence.

Input: MARSIWKGPFVDGYLIKKVQKLMESGKSEMIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNEEMVGRKLGEFAPTRTFHGHGADKKIKRK

Output: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


Instruction: Can you provide the functional description of the following protein sequence?

Output: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).


Instruction: Can you provide the functional description of the following protein sequence?

Input: MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFTGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL

Output: May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.


Instruction: Predict the functional description of the protein sequence below.

Output: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


Instruction: Predict the general functional description of the protein sequence.

Input: MSVSIKPLEDRIVVRPLEAEQTTASGLVIPDTAKEKPQEGQVVAVGPGRVAENGNRVPVDVAEGDVVLYSKYGGTEVKVGGEEYLVLSARDVLAVVTK

Output: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.


Instruction: Predict the general functional description of the protein sequence.

Input: MPNIDNTPLPSSFDAHPEFFQETKWQKVTRRLKEEPLIPIGYAATSYALWRAYKSMKARDSVELNRMFRARIYGHAFTLFAIVAGGIYYGQERKQRKEFEKALQEKQDQEKRDAWLRELEVRDKEDKDWRQRHAAMEMAAKEAEKKMG

Output: Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.


Instruction: Predict the functional description of the protein sequence below.

Output: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


Instruction: Predict the functional description of the protein sequence below.

Output: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.


Instruction: Predict the functional description of the protein sequence below.

Output: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.


Instruction: What is the functional description of the protein sequence?

Output: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.


Instruction: What is the functional description of the protein sequence?

Output: Probable transcription factor that promotes early floral meristem identity in synergy with APETALA1, FRUITFULL and LEAFY. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Seems to be partially redundant to the function of APETALA1 (By similarity).


Instruction: Predict the general functional description of the protein sequence.

Output: Transporter that specifically mediates the uptake of gallate.


Instruction: What is the functional description of the protein sequence?

Output: Beta-mannosyltransferase involved in cell wall biosynthesis. Responsible for addition of a hexose to the beta-mannose chain (By similarity).


Instruction: Predict the functional description of the protein sequence below.

Output: Has a role in meiosis.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MTTIAKQDKIFMKRSGAYHSELDKDIVQKAGNFPLMQFKTKVKVNPKFLLKGDDMDIVDEAITYYKANVFYKNFDMSICEADKLLVYLIFYIQSLLLKFNGRTKVECDKMAYSLAIENFALPGDGKFCLGGIVEPLKASEKEVVRQYMTAIRNETGLRLTQAVFKNDPTKCDKWWMCFNKRKFLNKTI

Output: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MFKRKSTAELAAQMAKLNGNKGFSSEDKGEWKLKLDNAGNGQAVIRFL

Output: Binds preferentially to single-stranded DNA and therefore, destabilizes double-stranded DNA. It is involved in DNA replication, repair and recombination. Binds ss-DNA as the replication fork advances and stimulates the replisome processivity and accuracy.


Instruction: Predict the functional description of the protein sequence below.

Input: MIKYFDKNNEVFNLIKDLTGRLNVEILEINIFRNKNNGKIQIVLYSKNFSLDIDFLTDLHKMILLILEANLKYGFTLELSTPGIDRKIKSDREFKIFEGKKIKLMLDNEFEEGFILESKPKSFIFKTDSKEVNVFYSDVKKARLV

Output: Required for maturation of 30S ribosomal subunits.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins (By similarity).


Instruction: What is the functional description of the protein sequence?

Input: MPVSIPNREEILADWEAHPMRRPRIQKVTINIGVGESGERLTKAEIMLQRLTGQKPIRRKAKKTNRDFGIRRGEPIAVKVTLRGPKAYEMLKRLLAAVDYKLKASSFDEHGNVCFGIEEHINIPGVEYDPEIGIFGMDVCVTLERPGFRVARRKRKRARIPTRHKLTKEEGMLYMMEEFGVEIVEEEG

Output: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MMSRTESRYSSQRTWLLSMVVLAALWSISVQRATARVINDDCPNLIGNRDLYKRVEWICEDCSNIFRNTGMATLCRKNCFFNEDFLWCVYATERTEEMSQLRQWVGILGAGRE

Output: Inhibits Y-organs where molting hormone (ecdysteroid) is secreted. A molting cycle is initiated when MIH secretion diminishes or stops (By similarity).


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MKHRDIRKVIIDALESAIGTDAIYFDGRPAVLEEGDFPAVAVYLTDAEYTGEELDADTWQAILHIEVFLEAQVPDSELDDWMETRVYPVLAEVPGLESLITTMVQQGYDYQRDDDMALWSSADLKYSITYDM

Output: Plays an essential role in tail assembly by capping the rapidly polymerizing tail once it has reached its requisite length and serving as the interaction surface for the completion protein.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).


Instruction: Can you provide the functional description of the following protein sequence?

Input: MSVLKKPDLTDPKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTLACVIGLSVLAPSPIGEKADPFATPLEILPEWYFFPTFNLLRVIPNKLLGVLSMAAVPVGLITVPFIESVNKFQNPFRRPVAMTVFVFSVVFAIWLGIGATMPINKALTLGLF

Output: Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.


Instruction: Predict the functional description of the protein sequence below.

Output: Part of an ATP-driven transport system CT_067/CT_068/CT_069/CT_070 for a metal. Probably responsible for energy coupling to the transport system.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MTSTSQLFDPYAEALMAIAREQGLEDRFGEDAALFRSTLAASADLRHLLENPTLFSSQKKAVLNQVFGSSVHPLVLNFLNLLVDRNRIAFLDGIADRYQALLRKLRNVVRADVSSAVPLTEAQVQVITEKVKQLTGAAGVEIESQVDADLLGGVIIKVGSQVLDASLRGQLKRISISLAA

Output: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.;


Instruction: What is the functional description of the protein sequence?

Output: An alpha subtype methylase, recognizes the double-stranded sequence 5'-GATC-3' and methylates A-2 (By similarity) . May be involved in methyl-directed DNA mismatch repair, initiation of chromosome replication and gene expression (By similarity).


Instruction: Predict the functional description of the protein sequence below.

Input: MAKVLKKPDLTNPALRAKLKKGMGHNYYGEPAWPNDLLYIFPVVIMGTIALVIGLAVMDPAMVGEPADPFATPLEILPEWYLYPTFQIFRVVPNKLLGVLMNASIPLGLMLIPFIESVNKFQNPFRRPVAMTVFLFGTLVTLWLGIGAAFPLDKSLTLGLF

Output: Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.


Instruction: Predict the general functional description of the protein sequence.

Input: DGVKLCDVPSGTWSGHCGSSSKCSQQCKDREHFAYGGACHYQFPSVKCFCKRQC

Output: Possesses antifungal activity insensitive to inorganic cations. Causes germ tubes and hyphae to swell and form multiple hyphal buds. Binds to the plasma membrane of the fungus. Has no inhibitory effect on insect gut alpha-amylase.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MQAKRTILLLLLLGMVALSSCGLREKHVQGLVNKFVPAGIVKNLLQAGIHKVAKMQYGCPIIKDYCSFHCNDLEKHEGYCHGTKCKCNIPNQYELF

Output: Inhibits voltage-gated potassium channel.


Instruction: What is the functional description of the protein sequence?

Output: May play a role in the modulation of host immune response.


Instruction: Predict the general functional description of the protein sequence.

Input: MKEIIAIIRPSKMAQTKTVLEGLGFPAMTANRVLGRGKQKAIVGELGFEVDNKELLNQPGDMRYIPKTMLTLIVPDEDASLVVEAIMKVNKSGQYGDGKIFVCPIEDIITVRTSERGEAAI

Output: Could be involved in the regulation of nitrogen fixation.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL

Output: Involved in the binding of tRNA to the ribosomes.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Regulates membrane-cell wall junctions and localized cell wall deposition. Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).


Instruction: What is the functional description of the protein sequence?

Output: May play a role in the modulation of host immune response.


Instruction: Predict the general functional description of the protein sequence.

Output: Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA. In contrast, when associated with RNA, it is termed N. During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).


Instruction: What is the functional description of the protein sequence?

Input: AATAATPATAATPARA

Output: Antifreeze proteins lower the blood freezing point.


Instruction: Predict the functional description of the protein sequence below.

Input: MPLIPPPNPQKTYQIAVLALGLVLLLAFVLISDHSPKVGDHLHNLPFGGEYKDGTKTIKYFQRPNQHSLSKTLAKSHNTTIFLIILGLIGTLHGLHYFSNNRRISSSLHCVLCQNKH

Output: Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata,.


Instruction: Can you provide the functional description of the following protein sequence?

Input: SQSVVATQLIPMNTALTPVMMEGKVTNPIGIPFAEMSQIVGKQVNTPVAKGQTIMPNMVKTYAA

Output: Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth (By similarity).


Instruction: Predict the functional description of the protein sequence below.

Output: Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).


Instruction: Can you provide the functional description of the following protein sequence?

Input: MSNQAVANRYAYALFQLAEEKSILSQVVQEMELVKEVVNTTPEFLQLLSHPKVTTEKKRAFIENSFKDSLSETSLHTLLLLVENKRIESLVDMIDSFKEMSYEAQDMAEAVVYSAKPLTSEEQAQIAVIFAKKVNKAKLLVTNVVNKDLLGGLKIRIGDRIYDGSVKSQLDRLERQLIAGTR

Output: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.;


Instruction: Predict the functional description of the protein sequence below.

Input: MENLTNISIELNQQFNTKEEAIRFCGEKLVEAGCVEPAYIEAMIERDQLLSVYMGNFIAIPHGTEEAKKLVKKSGICVVQVPEGVNFGTEEDEKIATVLFGIAGVGEEHLQLVQQIALYCSDMDNVVQLADALSKEEITENLAIA

Output: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.


Instruction: Predict the functional description of the protein sequence below.

Input: SGSCEVKTCWKAMPPFRKVGNVLKEKFDGATEVEQRKIGSTKVLVPKNSQFKPHTDEDLVYLDSSPDFCDHDLKNGVLGTSGRHCNKTSKAIDGCELMCCGRGFHTDEVEVVERCSCKF

Output: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development (By similarity).


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: GFKNVALSTARGF

Output: The exact physiological function is still unknown. This myotropic peptide is active on the oviduct and, to a lesser extent, on the hindgut. Transferred from the male to the female during copulation.


Instruction: Predict the functional description of the protein sequence below.

Output: Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate.


Instruction: Predict the functional description of the protein sequence below.

Output: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.


Instruction: Predict the functional description of the protein sequence below.

Output: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Exact function not known. Could be involved in copper resistance (By similarity).


Instruction: Predict the general functional description of the protein sequence.

Output: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.;


Instruction: What is the functional description of the protein sequence?

Input: MPLRVELKPFERIVIGQSVITNSDTRTTFLIDGDAPILREKDILTAETANTPVKRIYLCVQMMYLQNDIPAYQDLYLGFIKELIEAVPSFRETIEATSNHILSGNLYKALRELRPLIKREEELLSR

Output: Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation.


Instruction: Predict the general functional description of the protein sequence.

Input: MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAPLQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLRAEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK

Output: Produces ATP from ADP in the presence of a proton gradient across the membrane.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MTMLISLPTAPSVPNYQSLERPLNFTMAAAAKVRELIQEENNADLALRVYIQGGGCSGFQYGFEFDENRADDDLALETDGVVLLVDPLSLQYLLGAEVDYTESLTGAKFVIRNPNAKTTCGCGSSFSV

Output: Required for insertion of 4Fe-4S clusters for at least IspG.


Instruction: Predict the general functional description of the protein sequence.

Output: Controls the transcription of the pur operon for purine biosynthetic genes.


Instruction: What is the functional description of the protein sequence?

Input: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR

Output: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


Instruction: Predict the general functional description of the protein sequence.

Input: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW

Output: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.


Instruction: Predict the functional description of the protein sequence below.

Input: MSYAIIEIGGTQIRVEPGRFYEINHLDAAPEDSYVVDKVLLVKDGDNVTIGQPYVAGATVEGEILSHRRGRKVIVYKMQPKKKTRKKRGHRQELTRLLVKSISVNGTAIAEALEVDAKTPVVAG

Output: This protein binds to 23S rRNA in the presence of protein L20.


Instruction: What is the functional description of the protein sequence?

Input: SSTCIPSGQPCPYNENCCSQSCTFKENENGNTVKRCD

Output: Inhibits insect, but not mammalian, voltage-gated calcium channels (Cav).


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: ANDPQCLYGNVAAKF

Output: Has antifungal activity against M.arachidicola with an IC(50) of 125 uM, but not against F.oxysporum. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase with an IC(50) of 60 uM. Has mitogenic activity towards murine splenocytes. Lacks antiproliferative activity towards HepG2 hepatoma cells. Has antibacterial activity against the Gram-negative bacterium P.fluorescens. No antibacterial activity against the Gram-positive bacteria B.subtilis, B.cereus, B.megaterium, M.phei and S.aureus, or against the Gram-negative bacteria E.aerogenes, E.coli, P.aeruginosa, P.fluorescens and P.vulgaris.


Instruction: Can you provide the functional description of the following protein sequence?

Input: AGETHTVMINHAGRGAPKLVVGGKKLS

Output: Has antifungal activity against B.cinera, F.oxysporum and P.piricola with IC(50) values of 15.2 uM, 12.4 uM and 18.1 uM, respectively. Lacks hemagglutinating activity towards rabbit erythrocytes. Lacks deoxyribonuclease, ribonuclease and protease inhibitory activities.


Instruction: Predict the general functional description of the protein sequence.

Input: AGESSNEAKGMWFGPRL

Output: Myoactive.


Instruction: Predict the general functional description of the protein sequence.

Input: PQVGLIPFPRV

Output: Mediates visceral muscle contractile activity (myotropic activity).


Instruction: Predict the general functional description of the protein sequence.

Output: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).


Instruction: Can you provide the functional description of the following protein sequence?

Input: MWSDSLVSRICVPIIVVCTSIALLNVVSFRSECSCVVHISGAAIDIRGCSFTPDFIEYAKTLRVFNHRYQE

Output: Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata. May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity).


Instruction: Can you provide the functional description of the following protein sequence?

Output: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIVKAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI

Output: Binds to the 23S rRNA.


Instruction: Predict the functional description of the protein sequence below.

Output: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).


Instruction: Predict the general functional description of the protein sequence.

Input: MGLNIRVIAPDRIVWNAKAEEVILPTSTGQLGILSGHAPLLTALDIGVMRVRITNTWTSIVLFGGFAEVENDEILILVNGAEEASVINLDKANKELIESSSLLNEAKTNKEKFEATQKLRKAKARVQAANTLTNQSIY

Output: Produces ATP from ADP in the presence of a proton gradient across the membrane.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Probable receptor, which may be involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation.


Instruction: Predict the general functional description of the protein sequence.

Output: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.;


Instruction: Predict the general functional description of the protein sequence.

Output: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.


Instruction: Predict the general functional description of the protein sequence.

Output: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


Instruction: What is the functional description of the protein sequence?

Output: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MEDYKAFLDEKMSKVLLSLDNEYKTLRTGRISSNIFDKIFIQYHGQRTPITQVSSIRIPEARLVVIQPWDKTILNKIEQAILNSDLSMNPSSDGSVIRIKVPALTSERRQDIVKHAKKIAEEHKISTRNIRQDLNNKVKKQEKESEITEDSLKRILDDIQKSTDIYIKKIDAILESKIQEIMEV

Output: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.


Instruction: Predict the general functional description of the protein sequence.

Output: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.


Instruction: Predict the functional description of the protein sequence below.

Output: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


Instruction: Can you provide the functional description of the following protein sequence?

Output: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


Instruction: What is the functional description of the protein sequence?

Input: MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIETTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEIETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK

Output: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.


Instruction: Predict the general functional description of the protein sequence.

Input: MARIAGVDLPREKRIEVALTYIYGIGRSTARRVIRETGVDPDTRVRDLAEGEIAALRRYIDENLKVEGDLKREVNQNIRRLMDIGCYRGLRHRRGLPVRGQRTKTNARQRKGPRPAIGGRKK

Output: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.


Instruction: Predict the general functional description of the protein sequence.

Input: MHCPFCAAVDTKVIDSRLVSDGSQVRRRRQCLDCNERFTTFEVAELVLPRVIKSDEVREPFNEEKLRRGMLKALEKRPVSSDDVETAISHIKSQLRATGEREVPTKMVGNLVMEALKRLDKVAYIRFASVYRSFEDVREFGEEIARLQD

Output: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.;


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: MFS transporter; part of the gene cluster that mediates the biosynthesis the mycotoxin citrinin, a hepato-nephrotoxic compound to humans due to inhibition of respiration complex III .


Instruction: Predict the general functional description of the protein sequence.

Input: MERAIFAGGCFWCMGQPFEEQAGILSVRSGYTGGHLPNPSYEQVCAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTERQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIRHQFLEENWS

Output: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


Instruction: Predict the functional description of the protein sequence below.

Output: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.


Instruction: Predict the functional description of the protein sequence below.

Input: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNFRVDDSSES

Output: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.


Instruction: Can you provide the functional description of the following protein sequence?

Output: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


Instruction: Predict the general functional description of the protein sequence.

Input: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR

Output: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.;


Instruction: Can you provide the functional description of the following protein sequence?

Input: MKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVWMLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQENEVEE

Output: Activates the cell division inhibited by chromosomal DNA over-replication.


Instruction: Predict the general functional description of the protein sequence.

Output: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.


Instruction: What is the functional description of the protein sequence?

Output: Recruits and activates the Arp2/3 complex, which in turn leads to actin polymerization, promoting Rickettsia motility during infection.


Instruction: Predict the functional description of the protein sequence below.

Output: Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes.;


Instruction: Can you provide the functional description of the following protein sequence?

Input: MSKPKRERSLPDNEAKAIARMLRVSPQKLNLVAQLIRGRKASAALADLQFSRKRIAVDVKKCLESAIANAENNHDLDVDALIVSEAHVGKGIVMKRFAPRGRGRSGRIFKPFAQLTIVVRQVEAEASA

Output: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).;


Instruction: Can you provide the functional description of the following protein sequence?

Input: MAKAPASNAAQRVRKKVRKNVADGIAHVHASFNNTIITITDRQGNALSWASSGGQGFKGSRKSTPFAAQVASEVAGRAAIEQGVKNLDVEIKGPGPGRESSVRALAALGIRINMIADVTPVPHNGCRPQKRRRI

Output: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.


Instruction: Predict the general functional description of the protein sequence.

Output: Functions as a GC-rich promoter-specific transactivating transcription factor.


Instruction: Predict the general functional description of the protein sequence.

Output: May play a role in protection against oxidative stress.


Instruction: Predict the functional description of the protein sequence below.

Output: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.


Instruction: Predict the functional description of the protein sequence below.

Output: Not known; immunogenic protein.


Instruction: Predict the general functional description of the protein sequence.

Output: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.


Instruction: What is the functional description of the protein sequence?

Input: MKISTTRFGMIEISESDIILMRRGILGFEESKKYALLYQDVKNPFLWFQSLDDGATAFVVIDPFLLQPYYQPELNDDTLEKLEIDNPEDVALMVIVSIRSNPVLLTANLRAPIVINAAKKKACQVVLEDSRFPIRYDILKNREFLLGGHCYEISATAP

Output: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.


Instruction: What is the functional description of the protein sequence?

Input: MLTLPKYLRSELKKPLGQLYKSIDIIEEKLHQQLSEDKLIISIGDATTKNLIKLNIQPQICIVDNKIEREPVEHKLTHTDNLVHVNNPAGCITDELVKICIDSINTATSNNPVIIEVKGEEDLAVLPCILNAPKDTFILYGQPKEGVVLVCVNEAFNKAKHFYKQLNKE

Output: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).


Instruction: Predict the general functional description of the protein sequence.

Output: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.


Instruction: What is the functional description of the protein sequence?

Output: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.


Instruction: What is the functional description of the protein sequence?

Input: MFKLFSTKYMRSAPVVAAAWITMTAGIIIEFNRFFPDLLFHPMS

Output: May help in the organization of the PsaE and PsaF subunits.


Instruction: What is the functional description of the protein sequence?

Output: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.


Instruction: What is the functional description of the protein sequence?

Input: MSIETLVEEIGKLTLTEASELVKSLEEKFGVSAAPAVVAGVAAAAPAAAAAEEQTEFDVVLTAAGESKINVIKVVRAITGLGLKEAKDMVDGAPKTVKEAVSKDEAEKLMKELKDAGASVELK

Output: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.


Instruction: Predict the general functional description of the protein sequence.

Input: MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVAEEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEAALERAGKPGKR

Output: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.


Instruction: Predict the functional description of the protein sequence below.

Output: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


Instruction: Predict the general functional description of the protein sequence.

Input: MSKEDSFEMEGTVVDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVRVELTPYDLSKGRITYRAR

Output: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


Instruction: What is the functional description of the protein sequence?

Output: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.


Instruction: Predict the general functional description of the protein sequence.

Input: MATDTTEVKAIARFIRMSPYKVRRVLDQIRGLSYREALIILEFMPYRATEPVLTLLRSAAANAEHNAGLDRAELVITQAYADQGPVLKRFQPRAQGRAYQIRKPTCHITLAVAANAGAK

Output: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).;


Instruction: Can you provide the functional description of the following protein sequence?

Output: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


Instruction: What is the functional description of the protein sequence?

Output: The glycine cleavage system catalyzes the degradation of glycine.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.


Instruction: Predict the general functional description of the protein sequence.

Input: MKVKAVAKQVPVTPRKXRLVVDLIRGKKIKEAESILMFTPRSASPILAKLLKSAVANSVHNFNFNIDDLYVEEIFVNEGIRLPRLFPRAKG

Output: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).;


Instruction: Predict the general functional description of the protein sequence.

Input: MSFGSPGGRSVNIKPKPPERGSFPLDHDGECKFIISSYLQCLKKGGGVNDETCRKLAKSYLSCRMDHNLMAPECFENLGLVFDEDKKKREEASASTTAASESKKPST

Output: Required for the assembly of mitochondrial cytochrome c oxidase.


Instruction: Predict the general functional description of the protein sequence.

Output: Displays ATPase and GTPase activities.


Instruction: What is the functional description of the protein sequence?

Output: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


Instruction: Predict the functional description of the protein sequence below.

Input: MSEISVTQTLNTLGLRCPEPVMLVRKNIRHLNDGEILLIIADDPATTRDIPSFCQFMDHTLLQSEVEKPPFKYWVKRGK

Output: Sulfur carrier protein which probably makes part of a sulfur-relay system.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.


Instruction: Predict the general functional description of the protein sequence.

Output: Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).


Instruction: Can you provide the functional description of the following protein sequence?

Output: This protein is essential for plasmid replication; it is involved in copy control functions. In vitro, binds to the DNA repeat units, BCDD'D'', EFG and HIJ (By similarity).


Instruction: Predict the general functional description of the protein sequence.

Output: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.


Instruction: What is the functional description of the protein sequence?

Input: MSNIIKQLEQEQMKQNVPSFRPGDTVEVKVWVVEGTKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSIAVKRRGAVRKAKLYYLRERTGKAARIKERLN

Output: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


Instruction: Predict the general functional description of the protein sequence.

Output: Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MAKGQSLQDPFLNALRRERVPVSVYLVNGIKLQGTIESFDQFVVLLRNTVSQMVYKHAISTVVPARNVRVGPGGGYVQSNEGNQAEDDDVEQ

Output: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.


Instruction: Can you provide the functional description of the following protein sequence?

Output: An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MKEEKKLLLREVEEKISASQGFILLRYLGFTAAHSREFRNSLSGVSAEFEVLKKRIFFKAMQSAGFDIDSSDTSGHLGVVFAYDDAVSAAKQVLDFNKQYNDSLVFLAGRIDSANLSGKEVEAVAKLPSMKELRQQIVGLLAAPMSQVVGIMGSALSGVISCIDQKTQKN

Output: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MSRSLKKGPYINVKLEKKVLAMNESGKKVVVKTWSRASMISPDFVGHTVAVHNGNKFIPVYVTENMVGHKLGEFAPTRTFRGHAGNKKK

Output: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Specifically methylates the N7 position of a guanine in 16S rRNA.


Instruction: What is the functional description of the protein sequence?

Input: MKMLLDDLYEIVEPITADLGYILWGIEVVGSGKLTIRIFIDHENGVSVDDCQIVSKEISAVFDVEDPVSGKYILEVSSPGMNRQIFNIIQAQALVGFNVKAVTLAPVGSQTKFKGVLERVEGNNVILNLEDGKEISFDFDELKKLRVSPDFS

Output: Required for maturation of 30S ribosomal subunits.


Instruction: What is the functional description of the protein sequence?

Output: Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.


Instruction: What is the functional description of the protein sequence?

Input: MEQAKAVAKQVRIAPRKVRLVIDLIRGKQVGEAIAILKHTPKAASPVVEKLLNSAIANAEHNYEMEPNNLVISEAYVNEGVTLKRFRPRAQGRASRINKRTSHITLVVTEKKEG

Output: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).;


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MIYKVFYQASNDEVPVREKTDSIFVEAQSEREVRSKLKPYNYNIEFIQQVEGAFLEYEKQSENFKVLEL

Output: A non-essential component of RNA polymerase (RNAP).


Instruction: Can you provide the functional description of the following protein sequence?

Output: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.


Instruction: What is the functional description of the protein sequence?

Input: MAKAPIRARKRVRKTVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCAEAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV

Output: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.


Instruction: What is the functional description of the protein sequence?

Input: MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI

Output: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.


Instruction: What is the functional description of the protein sequence?

Output: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.


Instruction: Predict the general functional description of the protein sequence.

Input: MGVASSKILENLMEGTNFDKEEIERLRKRFMKLDKDGSGTIDKNEFLTIPGISSNPLAARLMDVFDEDGNGTIDFQEFIMGLSAFSGKTSKLDKLKFAFKIYDIDRDGYIGNGELFIVMKMMVGKNLQDEELQQIVDKTMMEADEDGDGRLNFHEFKNAVDSKSVASALTLNMI

Output: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity).


Instruction: Can you provide the functional description of the following protein sequence?

Output: Probably involved in transcriptional regulation.


Instruction: Can you provide the functional description of the following protein sequence?

Output: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


Instruction: Predict the general functional description of the protein sequence.

Output: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).


Instruction: Predict the general functional description of the protein sequence.

Output: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


Instruction: What is the functional description of the protein sequence?

Output: Specifically required for selective degradation of peroxisomes via macropexophagy.


Instruction: Predict the general functional description of the protein sequence.

Input: MHMKLILNLLVLLAPAAVFAAGGGHGDGHIPTSTIMFQAINLTILFAAIIYFTKDAIVSFFAGRKAAYLEAAQKSAFAREQAEKEFVDIKNKLANLDQTREENLRKAQTHAEDLKKQILEEANDVTKRIKNDAELTARLEVQRAQKELRTQLLQDSVEAARIVLTKDLGSSDQQKLQKDFINNVGV

Output: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.;


Instruction: Predict the functional description of the protein sequence below.

Input: MTNLLKKFNEQQMQVLAKEIPEFRPGDDLKVTFKVVDGTSERIQIFEGVCISKRNRGLHSSFAVRKVSHGESIVSQFFVYSPALVSVQVTRKGKVRRAKLYYLCKLFGKAARIKERTTYVKKKSK

Output: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MNNSNIIIFPEKYPCSISSLLIKDENDVFVLSHQNVLDCLQFQYPYNMYSQNHMLDDIYWTSQELIEDVLKILHLSGISINKYVIYVLVL

Output: Mediates the regulatory switch from transcription to RNA replication. Acts late in infection by inhibiting viral transcription and up-regulating RNA replication. Inhibition of transcription by protein M2-2 requires phosphorylation of the phosphoprotein.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MMTISDIVQIILFCALIFFPLGYLARHSLRRISDTTRLLFAKPRYVKPAGTLRRATKVKADKK

Output: Required for cellulose biosynthesis.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).


Instruction: Predict the functional description of the protein sequence below.

Output: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


Instruction: Predict the general functional description of the protein sequence.

Output: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.


Instruction: What is the functional description of the protein sequence?

Output: Involved in the catatabolism of testosterone. Catalyzes the hydration of 2-hydroxyhexa-2,4-dienoic acid to 4-hydroxy-2-oxohexanoic acid.


Instruction: Predict the functional description of the protein sequence below.

Input: MSGPNPNKQPVELNRTSLYWGLLCIFVLAILFSSYFFN

Output: One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.


Instruction: What is the functional description of the protein sequence?

Output: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


Instruction: Predict the general functional description of the protein sequence.

Output: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


Instruction: What is the functional description of the protein sequence?

Input: MALKVELKPHERIIVGNSVITNTDQRARLLIDGENVPILRERDILTPETANTPAKLVYLAVQLMYISPDPQTQHGTYFNLVRDIVTAVPSSWPIIEAINNNILNGDLYRALKDARKLIAYEEKLRGQYEATHPKAEADKDDVSTAA

Output: Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism.


Instruction: Predict the functional description of the protein sequence below.

Input: MTRIAGVNIPEKKHIVIALKKIYGIGNVLARKICKKTGINFSKKVNSLDSSEIELIRNEVLKLKIEGDLRREMTLNIKRLIDLGTYRGLRHKKHLPVRGQRTKTNARTRKGPRKPIKK

Output: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.


Instruction: What is the functional description of the protein sequence?

Input: MNYIPMTLKGAEKLREELKYLKQTKRSEIIKSISEARQYGDLKENAEYQAAKEQQYFCESRIKEIESKLMHSKIIDIKKIPFRDRVVFGSTITIKNLKTLEEKTYKIVGDDEANFKNNLISISSPLSRGLIGKKTLEIVNINTPSGIIKYKILKINYL

Output: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


Instruction: Predict the functional description of the protein sequence below.

Input: MKPSERRKARRLAVQAIYSWQLSGNNIADVEHEFLTEQSLDGVDVAYFRELFAGVATKKTQLDELIIPHLDRPIDEVSPVEKAIVRLAAYELTFRKDVPFKVAINEAIELAKAFGADESHKFVNGLLDKLVARK

Output: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


Instruction: What is the functional description of the protein sequence?

Output: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.


Instruction: Predict the general functional description of the protein sequence.

Input: MNVTSLSFPYGESIQWFCADNTKNLPASPLKEWLLAPGSLTQKLKGCCNEFEVRILGEGQCPPLDGEYPNQSAVWVREVLLCLDDVPWVFARTLIPQSLLSTRQADFLGLGTRPLGELLFSQDSFVPGRIEIARFATNSRLAHLAQSLAQNVEHELWGRRRYFHHNEEEMFVSEMFLPAAEQAIARLCP

Output: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.


Instruction: Predict the general functional description of the protein sequence.

Output: Probable transporter of a GTP-driven Fe(2+) uptake system.


Instruction: Can you provide the functional description of the following protein sequence?

Output: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.


Instruction: Predict the functional description of the protein sequence below.

Input: MSKTLSFKTYSAKPGEVKRTWHIIDAENQVLGRMAAQIANVLRGKHKPQFTPHIDTGDFVVVTNAAKVALSGKKRDDKTYFSHSHYPGGVRIDSVKDLLQKKPEKVIEHAVWGMLPHNNLGRQLFKKLKVYAGPEHPHAAQMPVEMKINQ

Output: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MAKKITGFIKLQIPAGGANPAPPVGPALGQKGVNIMEFCKQFNAKTQSEAGMIIPVVITVYSDKSFTFVTKTPPAAVLLLKEAKLQKGSGEPNRNKVGTVTMDQVRKIAELKRPDLNSIDLEGATQMVIGTARSMGIVVEG

Output: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


Instruction: What is the functional description of the protein sequence?

Output: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.


Instruction: Predict the general functional description of the protein sequence.

Output: Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


Instruction: Predict the general functional description of the protein sequence.

Input: MLDMTERQVESVLIEIPKGSRNKYEYDKEKKVIKFDRMLFSSMVYPCDYGFFPDTLALDGDPLDALVLTWEPTFPGCVIDVHPVALLDMKDDKGRDEKILCVPETDPLWNYIETLEQVPPHLLKEIVHFFETYKNLEGKHVIVIGWEGLDAAVDMLREAKSRYLEKNK

Output: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


Instruction: Predict the functional description of the protein sequence below.

Output: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.


Instruction: Predict the general functional description of the protein sequence.

Input: MEIDYYDYEKLLEKAYQELPENVKHHKSRFEVPGALVTIEGNKTIIENFKDIADALNRDPQHLLKFLLREIATAGTLEGRRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKRDRFHFLKCEACGAETPIQHL

Output: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.


Instruction: Predict the functional description of the protein sequence below.

Output: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.


Instruction: Predict the general functional description of the protein sequence.

Output: GTPase that plays an essential role in the late steps of ribosome biogenesis.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.


Instruction: Predict the functional description of the protein sequence below.

Output: GTPase that plays an essential role in the late steps of ribosome biogenesis.


Instruction: What is the functional description of the protein sequence?

Output: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


Instruction: Predict the functional description of the protein sequence below.

Output: Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.


Instruction: Can you provide the functional description of the following protein sequence?

Output: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.


Instruction: What is the functional description of the protein sequence?

Input: MPTDDPSDRPSGLLDQLSRLIETLAELDDDNGEQHGHSTIDRGRTRIDYDYAVSIGLGSDARSPSTPAGNADDAGDAETAHIETRASDDSDDLVVVADLPGVTDETAVDAAVEDTGALTISVGDDVVERLTLDDPGMTITSLTVTNQILELRVTPSEPSATDT

Output: May play a structural or regulatory role in gas vesicle synthesis.


Instruction: What is the functional description of the protein sequence?

Input: MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIKLDTETLQGERGSSNVSSIEITLSR

Output: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MTTSSGSRIGGLLHASLFSLLGLGLLLAGGFKTVERYHFLRTAQEAQGTVSALNAGGSHPQIDFTSVSGERISYPQGGFIFGYQVGEPVRVLYEAGRPAASAIVDDAGALWGTGAFLCGFGALFGIVGFRGLLGLRSSQPTSKGH

Output: Immunity protein that plays a role in preventing early activation of toxin Tse4.


Instruction: Predict the functional description of the protein sequence below.

Output: Envelope protein that binds to the cell surface to provide virion attachment to target cell.


Instruction: Predict the functional description of the protein sequence below.

Output: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MRCPACHHNGTRVLDSRPAHEGRSIRRRRECESCNHRFTTFEMIEEVPLIVVKKDGTRQEFSSDKILRGLIRACEKRPVPLETLEGIVNEVERELRGQGKNEVDSKEIGELVMERLANVDDVAYVRFASVYRQFKDINVFIQELKELMERDDR

Output: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.


Instruction: Predict the general functional description of the protein sequence.

Output: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.


Instruction: Predict the functional description of the protein sequence below.

Input: MMDSSPEKTNLELLYEQVCEQGREFEVVFYPMLPRLYEMMLPSLEARLNFLSVGYRHVAFSRYVHGDVDCVHREVMAQKMVLLTSILSKLLNVNGILEHQEYLNTE

Output: Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid.


Instruction: Can you provide the functional description of the following protein sequence?

Input: ANNAGARKAIRKIEARTEVN

Output: Binds directly to 16S ribosomal RNA.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MVRVKRGNVARKRRKKILKLASGFKGAHSKLFRVANQQVNKSLRYSYVGRKLKKRRFRRLWILRLNAASREEGLNYSKLVNSLKLLRIQLNRKSLSQLAMIDNDAFKRLVASSRV

Output: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).


Instruction: Predict the general functional description of the protein sequence.

Output: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity).


Instruction: Predict the functional description of the protein sequence below.

Output: Uptake of the purines adenine and guanine, and the pyrimidine uracil. Transport is probably proton-dependent.


Instruction: Predict the functional description of the protein sequence below.

Input: MKVIFLKDVKGKGKKGETKNVADGYANNFLIKNGYAVEASNAALSTLSAQKKKEDKLAAEELAEAKALKEKMEKLTVELKAKSGEGGRLFGSITSKQIAQTLEKTHGIKIDKRKMDLPEAIRALGHTKVPVKLHHEVTATLDVHVSEE

Output: Binds to the 23S rRNA.


Instruction: Predict the general functional description of the protein sequence.

Output: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.


Instruction: What is the functional description of the protein sequence?

Output: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.


Instruction: Predict the general functional description of the protein sequence.

Output: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.


Instruction: Predict the functional description of the protein sequence below.

Output: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MLDREGYRPNVGIILTNNRDEVFWGKRVREHSWQFPQGGIKPGESPETAMYRELYEEVGLLSQHVKIVGRTRDWLRYDVPNNWVRREWRGSYRGQKQIWYLLRLTGRDCDVNLRATRHPEFDGWRWHQYWAPVDEVIDFKRDVYLGALKELSSRFLRGMESYEDFAARQLSGNR

Output: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.


Instruction: Can you provide the functional description of the following protein sequence?

Output: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MRVGCDIIAISRIEKIHSRHGKNFLDKFLSPKEQILIKNPATLAGLWAAKEAASKALGVGICELCSFFDIEISKDEKNAPKLKYSQKITKDFNITQTSLSISHDNGFAIAIVAIV

Output: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.


Instruction: Predict the functional description of the protein sequence below.

Input: MALTNADRAEIIAKFARAENDTGSPEVQVALLTAQINDLQGHFKAHKHDHHSRRGLIRMVNQRRKLLDYLNGKDHERYTALIGALGLRR

Output: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.;


Instruction: Can you provide the functional description of the following protein sequence?

Output: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MEVKAIHRGARISAQKTRLVADQIRGLPVDKALNVLTFSPKKAAGIVKKVVLSAIANAEHNEGADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGN

Output: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).;


Instruction: What is the functional description of the protein sequence?

Input: MDDSKVSGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCAAMDQGKIPSEIKALLSGEDLKAAPNQVKHRAVKTEQKEKCP

Output: Probable regulator of creb1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle (By similarity).


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.;


Instruction: Predict the general functional description of the protein sequence.

Output: Involved in DNA repair and RecF pathway recombination.


Instruction: Predict the general functional description of the protein sequence.

Input: MKTLTDSFVYLGHWPSAGSFGFNTDILATNPINLSVVFGVLIFFGKGVLNDLLDNRKQRILNTIRNSEELREGAIQQLENALARLRKVETEADQFRVNGYSEIEREKLNLINSTYKTLKQLENYKNETILFEQQRTINQVRERVFQQALQGAIGTLNSCLSNELHLRTINANIGMFGTMKEITD

Output: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.;


Instruction: Predict the general functional description of the protein sequence.

Output: The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MASKKIDRLSFDATLEELETIVHQLEQGSLPLEEALKQFEQGVHLVRAGQQKLEQAEQKIQILLTQADGTEQAVPFQPEQGEE

Output: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLTRGRIVYRYK

Output: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


Instruction: Predict the functional description of the protein sequence below.

Input: MPKVGMQPIRRQQLIEATMAAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAALSVNDPRARLRAIAEGNFDDSQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLCAEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQEALLIIHNYIEQQLNIKYKC

Output: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MSKQTKTFEENLAELEGIVTKLERGDVALEEALAEFQKGMVLSKDLQKTLAEAEKTLVKVMQADGSEAEMD

Output: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.


Instruction: What is the functional description of the protein sequence?

Output: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.;


Instruction: Can you provide the functional description of the following protein sequence?

Input: MKNLFSLLKLTVFTLILFAVIYPLAIYGIAKLAPNQGKGETISVNGKVVGYQKIGQKFDKSNYFWGRPSAVDYNAAGSAGSNKGPSNADYLALVQKRIDTLLLVHPYLKKSDIPVDMVTASGSGLDPNISPQGALIQVKRIAKERMLDEAKVKSLVESKINTAVVGPETVNVLELNVALDQLK

Output: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Input: MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK

Output: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Specifically methylates the guanosine in position 1516 of 16S rRNA.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.


Instruction: Predict the functional description of the protein sequence below.

Input: MLKPLGDRVVLKAETEEEKTVGGIVLASNVKEKPTTGKVIAVGEGRTLENGQKLAPAVKEGDRVLFDKYAGNEVEYNGEKFLVVHAKDLVAIVE

Output: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.


Instruction: Can you provide the functional description of the following protein sequence?

Output: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


Instruction: What is the functional description of the protein sequence?

Output: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.


Instruction: Can you provide the functional description of the following protein sequence?

Input: MPRKGNVPKREVLADPIHGSMVVAKLINSVMLDGKKGTAQNIVYGAFDIIKERAEENPVEVFEKAMNNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLRWLVKYTRARGEKGMIEKLAKEIMDAANNTGSSVKKKEDTHKMAEANKAFAHYRW

Output: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


Instruction: Predict the general functional description of the protein sequence.

Output: With S4 and S12 plays an important role in translational accuracy.


Instruction: Generate the functional description in free-text form based on the protein sequence.

Output: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.


Instruction: Predict the general functional description of the protein sequence.

Input: MRCPYCQSEDTQVKDSRPAEDGAVIRRRRVCSVCGGRFTTFERVQLRDLMVVKKSGRRVPFDRDKLTRSIEVALRKRDVDNDRVERAISGIVRQLESSGEAEVTSDEIGRLAMDALKGIDDIAYIRFASVYRNFSKAVDFHNVIDELTVAETEDDLDA

Output: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.


Instruction: Predict the functional description of the protein sequence below.

Output: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).