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Ferrotitanium is a ferroalloy, an alloy of iron and titanium with between 10 and 20% iron and 45–75% titanium and sometimes a small amount of carbon. It is used in steelmaking as a cleansing agent for iron and steel; the titanium is highly reactive with sulfur, carbon, oxygen, and nitrogen, forming insoluble compounds ...
0
Metallurgy
A muffle furnace or muffle oven (sometimes retort furnace in historical usage) is a furnace in which the subject material is isolated from the fuel and all of the products of combustion, including gases and flying ash. After the development of high-temperature heating elements and widespread electrification in develop...
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Metallurgy
To show the visitors how Birminghams iron industry developed, the main museum displays a wide range of Tannehill artifacts that have survived. Visitors, through paying a visit to the museum, can learn from the graphic exhibits how iron was made by 13 different iron companies and six rolling mills and how Alabamas iron-...
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Metallurgy
Some cases of many genetic diseases are associated with variations in promoters or transcription factors. Examples include: * Asthma * Beta thalassemia * Rubinstein-Taybi syndrome
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Gene expression + Signal Transduction
The luteinizing hormone/choriogonadotropin receptor (LHCGR), also lutropin/choriogonadotropin receptor (LCGR) or luteinizing hormone receptor (LHR), is a transmembrane receptor found predominantly in the ovary and testis, but also many extragonadal organs such as the uterus and breasts. The receptor interacts with both...
1
Gene expression + Signal Transduction
Adhesion G protein-coupled receptors (adhesion GPCRs) are a class of 33 human protein receptors with a broad distribution in embryonic and larval cells, cells of the reproductive tract, neurons, leukocytes, and a variety of tumours. Adhesion GPCRs are found throughout metazoans and are also found in single-celled colon...
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Gene expression + Signal Transduction
When heating iron above 912 °C (1,674 °F), its crystal structure changes to a face-centered cubic (fcc) crystalline structure. In this form it is called gamma iron (γ-Fe) or austenite. γ-iron can dissolve considerably more carbon (as much as 2.04% by mass at 1,146 °C). This γ form of carbon saturation is exhibited in a...
0
Metallurgy
Like all metals, gold is insoluble in a water. Gold does however exhibit the distinctive properties that in the presence of cyanide ions, it dissolves in the presence of oxygen (or air). This transformation was reported in 1783 by Carl Wilhelm Scheele, but it was not until the late 19th century, that the reactions wer...
0
Metallurgy
If the drip rate is quicker than one drop per minute, most of the CaCO will be carried to the ground, still in solution. The leachate solution then has a chance to absorb CO from the atmosphere (or degas CO depending on reaction) and deposit the CaCO on the ground as a stalagmite. In most locations within manmade concr...
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Metallurgy
There are several, largely empirical laws of recrystallization: * Thermally activated. The rate of the microscopic mechanisms controlling the nucleation and growth of recrystallized grains depend on the annealing temperature. Arrhenius-type equations indicate an exponential relationship. * Critical temperature. Followi...
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Metallurgy
A notable feature of eukaryotic nuclear pre-mRNA introns is the relatively high level of conservation of the primary sequences of 5 and 3 splice sites over a great range of organisms. Between 1989 and 1991, several groups reported four independent examples of introns with a splice site that differed from the common int...
1
Gene expression + Signal Transduction
The classic view of pRb's role as a tumor suppressor and cell cycle regulator developed through research investigating mechanisms of interactions with E2F family member proteins. Yet, more data generated from biochemical experiments and clinical trials reveal other functions of pRb within the cell unrelated (or indirec...
1
Gene expression + Signal Transduction
A scleroscope is a device used to measure rebound hardness. It consists of a steel ball dropped from a fixed height. The device was invented in 1907. As an improvement on this rough method, the Leeb Rebound Hardness Test, invented in the 1970s, uses the ratio of impact and rebound velocities (as measured by a magnet...
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Metallurgy
Taking into account the HiFIT process during development, on same load level and same lifetime, the construction can be slimmed down specifically. Extensive experimental investigations on structural details and FEM-supported-design methods has shown the high efficiency with conventional S235, S355J2 and fine grain stee...
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Metallurgy
A target peptide is a short (3-70 amino acids long) peptide chain that directs the transport of a protein to a specific region in the cell, including the nucleus, mitochondria, endoplasmic reticulum (ER), chloroplast, apoplast, peroxisome and plasma membrane. Some target peptides are cleaved from the protein by signa...
1
Gene expression + Signal Transduction
Pre-mRNAs of the Transformer (Tra) gene of Drosophila melanogaster undergo alternative splicing via the alternative acceptor site mode. The gene Tra encodes a protein that is expressed only in females. The primary transcript of this gene contains an intron with two possible acceptor sites. In males, the upstream accept...
1
Gene expression + Signal Transduction
# Accessibility: Run over 200 regularly updated analysis and visualization tools (that support data preprocessing, gene expression analysis, proteomics, Single nucleotide polymorphism (SNP) analysis, flow cytometry, and next-generation sequencing) and create analytic workflows without any programming through a point an...
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Gene expression + Signal Transduction
Phosphoinositide phospholipase C performs its catalytic function at the plasma membrane where the substrate PIP is present. This membrane docking is mediated mostly by lipid-binding domains (e.g. PH domain and C2 domain) that display affinity for different phospholipid components of the plasma membrane. It is important...
1
Gene expression + Signal Transduction
In the US, more copper is recovered and put back into service from recycled material than is derived from newly mined ore. Copper's recycle value is so great that premium-grade scrap normally has at least 95% of the value of primary metal from newly mined ore. In Europe, about 50% of copper demand comes from recycling ...
0
Metallurgy
*PSMA1 NM_002786 *PSMA2 NM_002787 *PSMA3 NM_002788 *PSMA4 NM_002789 *PSMA5 NM_002790 *PSMA6 NM_002791 *PSMA7 NM_002792 Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7), *PSMB1 NM_002793 Homo sapiens proteasome (prosome, macropain) subunit, beta type, 1 (PSMB1), mRNA *PSMB2 NM_0...
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Gene expression + Signal Transduction
By the early 1970s the climate for R&D was again changing. Government R&D budgets continued to tighten. The earlier pattern of Fulmer sponsorship, with a large proportion of contracts from UK ministries and government agencies, no longer applied. In 1955 this proportion had been 70% but by 1970 it had fallen to 45%. B...
0
Metallurgy
A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior. Hormones are required for the correct development of animals, plants and fungi. Due to ...
1
Gene expression + Signal Transduction
Phototropins are photoreceptor proteins (more specifically, flavoproteins) that mediate phototropism responses in various species of algae, fungi and higher plants. Phototropins can be found throughout the leaves of a plant. Along with cryptochromes and phytochromes they allow plants to respond and alter their growth i...
1
Gene expression + Signal Transduction
Moreover, Ca2+/calmodulin (CaM)-dependent protein kinase II (CaMKII) is best recognized for its roles in the brain, particularly in the neocortex and hippocampal regions because it serves as a ubiquitous mediator of cellular Ca2+ signals. CaMKII is abundant in the nervous system, mainly concentrated in the synapses in ...
1
Gene expression + Signal Transduction
Binding of Ca by the EF-hands causes an opening of the N- and C-domains, which exposes hydrophobic target-binding surfaces. These surfaces interact with complementary nonpolar segments on target proteins, typically consisting of groups of bulky hydrophobic amino acids separated by 10–16 polar and/or basic amino acids....
1
Gene expression + Signal Transduction
The exceptional yield strength of nanocrystalline metals is due to grain boundary strengthening, as grain boundaries are extremely effective at blocking the motion of dislocations. Yielding occurs when the stress due to dislocation pileup at a grain boundary becomes sufficient to activate slip of dislocations in the ad...
0
Metallurgy
Recent studies have reported the ability of drug-resistant cancer cells to acquire mitogenic signals from previously neglected autocrine loops, causing tumor recurrence. For example, despite widespread expression of epidermal growth factor receptors (EGFRs) and EGF family ligands in non-small-cell lung cancer (NSCLC), ...
1
Gene expression + Signal Transduction
It is possible to perform a CD4 co-receptor blockade, using antibodies, in order to lower T cell activation and counteract autoimmune disorders. This blockade appears to elicit a "dominant" effect, that is to say, once blocked, the T cells do not regain their ability to become active. This effect then spreads to native...
1
Gene expression + Signal Transduction
The modern X-ray fluorescence (XRF) is also a non-destructive technique that is suitable for normal assaying requirements. It typically has an accuracy of 2 to 5 parts per thousand and is well-suited to relatively flat and large surfaces. It is a quick technique taking about three minutes, and the results can be automa...
0
Metallurgy
In the old days of traditional manufacturing, steel and other metals arrived at factories in an untreated and unpainted state. Companies would fabricate and paint or treat the metal components of their product before assembly. This was costly, time-consuming, and environmentally harmful. The coil coating process was pi...
0
Metallurgy
Diffusion hardening is a process used in manufacturing that increases the hardness of steels. In diffusion hardening, diffusion occurs between a steel with a low carbon content and a carbon-rich environment to increase the carbon content of the steel and ultimately harden the workpiece. Diffusion only happens through ...
0
Metallurgy
PRKAR1A has been shown to interact with: * AKAP10, * AKAP1, * AKAP4, * ARFGEF1, * ARFGEF2, * Grb2, * MYO7A, * PRKAR1B, and * UBE2M.
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Gene expression + Signal Transduction
The alkali metal polysulfides arise by treatment of a solution of sulfide, e.g. sodium sulfide, with elemental sulfur: In some cases, these anions have been obtained as organic salts, which are soluble in organic solvents. The energy released in the reaction of sodium and elemental sulfur is the basis of battery techno...
0
Metallurgy
Graham Charles Wood FRS (6 February 1934—4 November 2016) was an English corrosion scientist. Born in Farnborough, he went on to study metallurgy at Cambridge. Following postdoctoral work at Cambridge, he moved to Manchester, where his career in corrosion science would be based, starting at the Manchester College of Sc...
0
Metallurgy
Embrittlement is a series complex mechanism that is not completely understood. The mechanisms can be driven by temperature, stresses, grain boundaries, or material composition. However, by studying the embrittlement process, preventative measures can be put in place to mitigate the effects. There are several ways to st...
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Metallurgy
Transcription factor II E (TFE) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. It is a tetramer of two alpha and two beta chains and interacts with TAF6/TAFII80, ATF7IP, and varicella-zoster virus IE63 protein. TFE recruits TFH to the initiation complex and sti...
1
Gene expression + Signal Transduction
The range of applications for SMAs has grown over the years, a major area of development being dentistry. One example is the prevalence of dental braces using SMA technology to exert constant tooth-moving forces on the teeth; the nitinol archwire was developed in 1972 by orthodontist George Andreasen. This revolutioniz...
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Metallurgy
Unsuccessful transfer or abortive transfer is any bacterial DNA transfer from donor cells to recipient cells that fails to survive transduction and conjugation. In all cases, the transferred fragment could be diluted during the proliferation phase. Failures in the integration of the transferred DNA in the genetic ma...
1
Gene expression + Signal Transduction
Air pollutants generated by aluminium smelters include carbonyl sulfide, hydrogen fluoride, polycyclic compounds, lead, nickel, manganese, polychlorinated biphenyls, and mercury. Copper smelter emissions include arsenic, beryllium, cadmium, chromium, lead, manganese, and nickel. Lead smelters typically emit arsenic, an...
0
Metallurgy
In molecular biology, a termination factor is a protein that mediates the termination of RNA transcription by recognizing a transcription terminator and causing the release of the newly made mRNA. This is part of the process that regulates the transcription of RNA to preserve gene expression integrity and are present i...
1
Gene expression + Signal Transduction
The Wnt signaling pathways are initiated by the binding of the Wnt ligand to the Fz receptor. There are three different molecular pathways downstream of the Wnt/Fz interaction. The majority of research has focused on the Wnt/β-catenin pathway (also known as the "canonical" Wnt pathway), which manages cell fate determ...
1
Gene expression + Signal Transduction
Mice with truncated EpoR are viable, which suggests Jak2 activity is sufficient to support basal erythropoiesis by activating the necessary pathways without phosphotyrosine docking sites being needed. EpoR-H form of EpoR truncation contains the first, and, what can be argued, the most important tyrosine 343 that serves...
1
Gene expression + Signal Transduction
Corrosion in space has the highest impact on spacecraft with moving parts. Early satellites tended to develop problems with seizing bearings. Now the bearings are coated with a thin layer of gold. Different materials resist corrosion in space differently. For example, aluminium is slowly eroded by atomic oxygen, while ...
0
Metallurgy
It is thought that erythroid differentiation is primarily dependent on the presence and induction of erythroid transcriptional factors such as GATA-1, FOG-1 and EKLF, as well as the suppression of myeloid/lymphoid transcriptional factors such as PU.1. Direct and significant effects of EpoR signaling specifically upon t...
1
Gene expression + Signal Transduction
Roses metal, Rose metal or Roses alloy is a fusible alloy with a low melting point. Rose's metal consists of 50% bismuth, 25–28% lead and 22–25% tin. Its melting point is between . The alloy does not appreciably contract or expand on solidification, this characteristic being a function of its bismuth percentage, but do...
0
Metallurgy
Although the problem was first found in brass, any alloy containing copper will be susceptible to the problem. It includes copper itself (as used in pipe for example), bronzes and other alloys with a significant copper content. Like all problems with hairline cracks, detection in the early stages of attack is difficult...
0
Metallurgy
In high-temperature metal joining processes (welding, brazing and soldering), fluxes are nearly inert at room temperature, but become strongly reducing at elevated temperatures, preventing oxidation of the base and filler materials. The role of flux is typically dual: dissolving the oxides already present on the metal ...
0
Metallurgy
When applied to existing constructions, the lifetime can be extended considerably. If no macroscopically visible cracks are present, HiFIT is a very suitable remediation tool. With timely remediation of existing structures there is practically no difference to the life of new treated welds. This gives the potential to ...
0
Metallurgy
It has been shown previously that OMgp (oligodendrocyte myelin glycoprotein) clusters at nodes of Ranvier and may regulate paranodal architecture, node length and axonal sprouting at nodes. However, a follow-up study showed that the antibody used previously to identify OMgp at nodes crossreacts with another node-enric...
1
Gene expression + Signal Transduction
Understanding the mechanical properties of Heusler compounds is paramount for temperature-sensitive applications (e.g. thermoelectrics) for which some sub-classes of Heusler compounds are used. However, experimental studies are rarely encountered in literature. In fact, the commercialization of these compounds is limit...
0
Metallurgy
Activated Ras then activates the protein kinase activity of a RAF kinase. The RAF kinase phosphorylates and activates a MAPK/ERK Kinase (MEK1 or MEK2). The MEK phosphorylates and activates a mitogen-activated protein kinase (MAPK). RAF and MAPK/ERK are both serine/threonine-specific protein kinases. MEK is a serine/tyr...
1
Gene expression + Signal Transduction
Titanium powder metallurgy (P/M) offers the possibility of creating net shape or near net shape parts without the material loss and cost associated with having to machine intricate components from wrought billet. Powders can be produced by the blended elemental technique or by pre-alloying and then consolidated by meta...
0
Metallurgy
RNA-induced transcriptional silencing (RITS) is a form of RNA interference by which short RNA molecules – such as small interfering RNA (siRNA) – trigger the downregulation of transcription of a particular gene or genomic region. This is usually accomplished by posttranslational modification of histone tails (e.g. meth...
1
Gene expression + Signal Transduction
The following is a list of human hepatocyte nuclear factors (see also boxes to the right for additional information about these proteins):
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Gene expression + Signal Transduction
The first recorded experimental work in copper was conducted by Cushing in 1894 in order to demonstrate that copper plate found in Hopewell mounds in Ohio could have been produced by the Hopewell people and not come from European trade. In his experiments, Cushing used antler and stone tools to cut out sheets of coppe...
0
Metallurgy
Moreover, because the assembly of the full-length gene product relies on the efficient and specific alignment of long single stranded oligonucleotides, critical parameters for synthesis success include extended sequence regions comprising secondary structures caused by inverted repeats, extraordinary high or low GC-con...
1
Gene expression + Signal Transduction
The integrated stress response is a cellular stress response conserved in eukaryotic cells that downregulates protein synthesis and upregulates specific genes in response to internal or environmental stresses.
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Gene expression + Signal Transduction
Using the model organism Drosophila melanogaster, data has been compiled regarding the genomic information and sequencing of this organism. A prediction model exists in which a researcher can upload his or her genomic information and use a splice site prediction database to gather information about where the splice sit...
1
Gene expression + Signal Transduction
SMRT (silencing mediator of retinoic acid and thyroid hormone receptor), also known as NCoR2, is an alternatively spliced SRC-1(steroid receptor coactivator-1). It is negatively and positively affected by MAPKKK (mitogen activated protein kinase kinase kinase) and casein kinase 2 phosphorylation, respectively. SMRT has...
1
Gene expression + Signal Transduction
Besides trying to re-activate the tumor suppressive function of pRb, one other distinct approach to treat dysregulated pRb pathway cancers is to take advantage of certain cellular consequences induced by pRb loss. It has been shown that E2F stimulates expression of pro-apoptotic genes in addition to G1/S transition gen...
1
Gene expression + Signal Transduction
Archaeologist George Eogan, in his study of Bronze Age gold-working, noted that very few Bronze Age gold artefacts had been discovered through "controlled archaeological investigation", with the majority instead having been unearthed "by chance", as a result of "agricultural activities or peat-cutting". In the 21st c...
0
Metallurgy
The TRIM family is split into two groups that differ in domain structure and genomic organization: * Group 1 members possess a variety of C-terminal domains, and are represented in both vertebrate and invertebrates * Group 2 is absent in invertebrates, possess a C-terminal SPRY domain Members of the family include: * ...
1
Gene expression + Signal Transduction
Williams commenced lecturing at McGill University in 1960, and was selected to be the Chairman of the Department of Mining and Metallurgy in 1966. As Chairman, he was instrumental in expanding the department at a time when only six degree programs in Metallurgical Engineering were being offered in Canadian universities...
0
Metallurgy
The mined ore is usually crushed into small chunks and heaped on an impermeable plastic or clay lined leach pad where it can be irrigated with a leach solution to dissolve the valuable metals. While sprinklers are occasionally used for irrigation, more often operations use drip irrigation to minimize evaporation, prov...
0
Metallurgy
Partial agonists are defined as drugs that, at a given receptor, might differ in the amplitude of the functional response that they elicit after maximal receptor occupancy. Although they are agonists, partial agonists can act as a competitive antagonist in the presence of a full agonist, as it competes with the full ag...
1
Gene expression + Signal Transduction
Many hormones and their structural and functional analogs are used as medication. The most commonly prescribed hormones are estrogens and progestogens (as methods of hormonal contraception and as HRT), thyroxine (as levothyroxine, for hypothyroidism) and steroids (for autoimmune diseases and several respiratory disorde...
1
Gene expression + Signal Transduction
The closed loop recirculation is a proven method of directly monitoring hydrogen in molten aluminium. A small volume of carrier gas, usually nitrogen, is brought in contact with the melt by means of an immersed probe, and is continuously recirculated in the closed loop until its hydrogen content reaches equilibrium wit...
0
Metallurgy
The dominant technology used for the production of transgenic plants for transient expression is Agrobacterium-mediated genetic transformation, or "agroinfiltration," and virus expression machinery. Agrobacterium tumefaciens and related Agrobacterium species are well-known plant pathogens that have been engineered to e...
1
Gene expression + Signal Transduction
RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells. It consists of RNA polymerase II, a subset of general transcription factors, and regulatory proteins known as .
1
Gene expression + Signal Transduction
All the structural genes of an operon are turned ON or OFF together, due to a single promoter and operator upstream to them, but sometimes more control over the gene expression is needed. To achieve this aspect, some bacterial genes are located near together, but there is a specific promoter for each of them; this is c...
1
Gene expression + Signal Transduction
In addition to RNA, proteins can undergo splicing. Although the biomolecular mechanisms are different, the principle is the same: parts of the protein, called inteins instead of introns, are removed. The remaining parts, called exteins instead of exons, are fused together. Protein splicing has been observed in a wide r...
1
Gene expression + Signal Transduction
Prp24 (precursor RNA processing, gene 24) is a protein part of the pre-messenger RNA splicing process and aids the binding of U6 snRNA to U4 snRNA during the formation of spliceosomes. Found in eukaryotes from yeast to E. coli, fungi, and humans, Prp24 was initially discovered to be an important element of RNA splicing...
1
Gene expression + Signal Transduction
Another regulatory element located upstream of the gene is an enhancer. Enhancers function as a "turn on" switch in gene expression and will activate the promoter region of a particular gene while silencers act as the "turn off" switch. Though these two regulatory elements work against each other, both sequence types a...
1
Gene expression + Signal Transduction
An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word intron is derived from the term agenic regi, i.e., a region inside a gene. The term intron refers to both the DNA sequence within a gene and the corresponding RNA sequence in RNA transcripts. The non...
1
Gene expression + Signal Transduction
In West Africa, copper was used as medium of exchange, symbols of status and kingship, jewelry, and ritual purposes; this was a part of Bantu tradition prior to their expansion into Central Africa. The use of copper in the Iron Age of Central Africa was produced because of indigenous or internal demand rather than thos...
0
Metallurgy
The origin of the name Ariconium is uncertain, as is its pre-Roman name. The Romans often named a place in recognition of some feature of the terrain, or in recognition of the people then living in the area. There is a similarity to other Roman place-names such as Viroconium (post-Roman Welsh: Caer Guricon), also known...
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Metallurgy
Protein arginine N-methyltransferase-4 (PRMT4/CARM1) methylation of arginine residues within proteins plays a critical key role in transcriptional regulation (see the PRMT4 pathway on the left). PRMT4 binds to the classes of transcriptional activators known as p160 and CBP/p300. The modified forms of these proteins are...
1
Gene expression + Signal Transduction
mTOR is implicated in the failure of a pruning mechanism of the excitatory synapses in autism spectrum disorders.
1
Gene expression + Signal Transduction
Corinthian bronze, also named Corinthian brass or aes Corinthiacum, was a highly valuable metal alloy in classical antiquity. It is thought to be an alloy of copper with gold or silver (or both), although it has also been contended that it was simply a very high grade of bronze, or a kind of bronze that was manufactur...
0
Metallurgy
Integration was the watchword as the various processes were brought together by large corporations, from mining the iron ore to shipping the finished product to wholesalers. The typical steelworks was a giant operation, including blast furnaces, Bessemer converters, open-hearth furnaces, rolling mills, coke ovens and f...
0
Metallurgy
The first recorded attempt to make copper clad steel wire took place in the early 1860s. Although for over 100 years people had been suggesting various ways of uniting copper and steel, it was not until the period mentioned that Farmer and Milliken tried wrapping a strip of copper about a steel wire. American engineers...
0
Metallurgy
Historically, this approach was seen through the New England colonies. Virtually every old home is a clapboard structure fitted with shutters applied in this manner. They were likely hung on the casing to allow for the frost heaves and movement of the structures in the harsh New England winters. The shutters simply all...
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Metallurgy
Regulatory sequences for the insulin gene are: * A5 * Z * negative regulatory element (NRE) * C2 * E2 * A3 * cAMP response element * A2 * CAAT enhancer binding (CEB) * C1 * E1 * G1
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Gene expression + Signal Transduction
When a concrete structure is heavily reinforced, the very dense rebar network can block the contraction movement of the protecting concrete cover located above the external layer of reinforcement bars due to the natural drying shrinkage process. As a consequence, a network of fissures with the characteristic honeycomb ...
0
Metallurgy
A ρ factor (Rho factor) is a bacterial protein involved in the termination of transcription. Rho factor binds to the transcription terminator pause site, an exposed region of single stranded RNA (a stretch of 72 nucleotides) after the open reading frame at C-rich/G-poor sequences that lack obvious secondary structure. ...
1
Gene expression + Signal Transduction
Flocculation is widely employed to measure the progress of curd formation in the initial stages of cheese making to determine how long the curds must set. The reaction involving the rennet micelles are modeled by Smoluchowski kinetics. During the renneting of milk the micelles can approach one another and flocculate, a...
0
Metallurgy
Humans have between 10 and 20 million olfactory receptor neurons (ORNs). In vertebrates, ORNs are bipolar neurons with dendrites facing the external surface of the cribriform plate with axons that pass through the cribriform foramina with terminal end at olfactory bulbs. The ORNs are located in the olfactory epitheli...
1
Gene expression + Signal Transduction
The synthesis and degradation of (p)ppGpp have been most extensively characterized in the bacterial model organism Escherichia coli.
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Gene expression + Signal Transduction
The Ames process is a process by which pure uranium metal is obtained. It can be achieved by mixing any of the uranium halides (commonly uranium tetrafluoride) with magnesium metal powder or aluminium metal powder.
0
Metallurgy
Whiskers can cause short circuits and arcing in electrical equipment. The phenomenon was discovered by telephone companies in the late 1940s and it was later found that the addition of lead to tin solder provided mitigation. The European Restriction of Hazardous Substances Directive (RoHS), which took effect on July 1...
0
Metallurgy
Binding of targeting sequence elements by CTCF can block the interaction between enhancers and promoters, therefore limiting the activity of enhancers to certain functional domains. Besides acting as enhancer blocking, CTCF can also act as a chromatin barrier by preventing the spread of heterochromatin structures.
1
Gene expression + Signal Transduction
GenePattern is available: # As a free public web application, hosted on Amazon Web Services. Users can create accounts, perform analyses, and create pipelines on the server. # As open-source software that can be downloaded and installed locally. # Public web servers hosted by other organizations.
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Gene expression + Signal Transduction
Cyclic Corrosion Testing (CCT) has evolved in recent years, largely within the automotive industry, as a way of accelerating real-world corrosion failures, under laboratory controlled conditions. As the name implies, the test comprises different climates which are cycled automatically so the samples under test underg...
0
Metallurgy
This piece is the smaller part of the fragment broken during Bahadur Shah's reign. Henry Cousens (1902–03) measured its length as . The part with the square cross-section measured , while the part with the octagonal section measured . Klaus Roessler (1995) found this piece to be long. Roessler estimated its weight at ...
0
Metallurgy
Brinelling is a material surface failure caused by Hertz contact stress that exceeds the material limit. It usually occurs in situations where a significant load force is distributed over a relatively small surface area. Brinelling typically results from a heavy or repeated impact load, either while stopped or during r...
0
Metallurgy
Alloying a metal is done by combining it with one or more other elements. The most common and oldest alloying process is performed by heating the base metal beyond its melting point and then dissolving the solutes into the molten liquid, which may be possible even if the melting point of the solute is far greater than ...
0
Metallurgy
When the RNA transcript reaches 7 nucleotides long, transcription enters the elongation phase, the beginning of which is characterised by the collapsing of the DNA bubble and the ejection of TFIIB. This is thought to be because the nascent RNA clashes with the B linker helix when it is 6 bases long and upon further elo...
1
Gene expression + Signal Transduction
An MTC provides traceability and assurance to the end user about the quality of the steel used and the process used to produce it. Typically a European MTC will be produced to EN 10204. High quality steels for pressure vessel of structural purposes will be declared to 2.1 or 2.2 or certificated to 3.1 or 3.2. (EDIT: t...
0
Metallurgy
NbGe was discovered to be a superconductor in 1973 and for 13 years (until the discovery in 1986 of the cuprate superconductors) it held the record as having the highest critical temperature. It has not been as widely used for superconductive applications as niobium–tin or niobium–titanium.
0
Metallurgy
Symptoms of M2DS include infantile hypotonia and failure to thrive, delayed psychomotor development, impaired speech, abnormal or absent gait, epilepsy, spasticity, gastrointestinal motility problems, recurrent infections, and genitourinary abnormalities. Many of those affected by M2DS also fit diagnostic criteria for ...
1
Gene expression + Signal Transduction