adding responsive column and documentation
Browse files- README.md +12 -0
- knockout.parquet +2 -2
- overexpression.parquet +2 -2
README.md
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Average log2 fold change across dye orientations,
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providing a dye-independent estimate of gene expression
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change upon transcription factor overexpression.
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- config_name: knockout
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description: Deletion/knockout perturbation normalized log2 fold changes
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dye-independent estimate of gene expression change upon
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transcription factor deletion.
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role: quantitative_measure
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---
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# Hughes 2006
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Average log2 fold change across dye orientations,
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providing a dye-independent estimate of gene expression
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change upon transcription factor overexpression.
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- name: responsive
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dtype: float64
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description: >-
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abs(mean_norm_log2fc) `>` 1. Note that the authors do not have a threshold
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in their paper. They do use a zscore `>` 3 which they say is about a
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1.58 FC. That yielded exceptionally few DE genes, so I reduced the value
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- config_name: knockout
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description: Deletion/knockout perturbation normalized log2 fold changes
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dye-independent estimate of gene expression change upon
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transcription factor deletion.
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role: quantitative_measure
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- name: responsive
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dtype: float64
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description: >-
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abs(mean_norm_log2fc) `>` 1. Note that the authors do not have a threshold
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in their paper. They do use a zscore `>` 3 which they say is about a
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1.58 FC. That yielded exceptionally few DE genes, so I reduced the value
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---
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# Hughes 2006
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knockout.parquet
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version https://git-lfs.github.com/spec/v1
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oid sha256:
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size
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version https://git-lfs.github.com/spec/v1
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oid sha256:35b874d4fa0ef9dcb8b4447a616ca308e0505412bd9750513031d5397b6c54a0
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size 7473318
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overexpression.parquet
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version https://git-lfs.github.com/spec/v1
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oid sha256:
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size
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version https://git-lfs.github.com/spec/v1
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oid sha256:ddfbe2f1c1d4fb77d75fcd6085f8a3f28881fea821e5b36288c7ea3f291d1c91
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size 8403772
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