cmatkhan commited on
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8cf3dc9
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1 Parent(s): 80b0f9e

adding responsive column and documentation

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  1. README.md +12 -0
  2. knockout.parquet +2 -2
  3. overexpression.parquet +2 -2
README.md CHANGED
@@ -134,6 +134,12 @@ configs:
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  Average log2 fold change across dye orientations,
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  providing a dye-independent estimate of gene expression
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  change upon transcription factor overexpression.
 
 
 
 
 
 
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  - config_name: knockout
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  description: Deletion/knockout perturbation normalized log2 fold changes
@@ -199,6 +205,12 @@ configs:
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  dye-independent estimate of gene expression change upon
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  transcription factor deletion.
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  role: quantitative_measure
 
 
 
 
 
 
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  ---
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  # Hughes 2006
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  Average log2 fold change across dye orientations,
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  providing a dye-independent estimate of gene expression
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  change upon transcription factor overexpression.
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+ - name: responsive
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+ dtype: float64
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+ description: >-
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+ abs(mean_norm_log2fc) `>` 1. Note that the authors do not have a threshold
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+ in their paper. They do use a zscore `>` 3 which they say is about a
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+ 1.58 FC. That yielded exceptionally few DE genes, so I reduced the value
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  - config_name: knockout
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  description: Deletion/knockout perturbation normalized log2 fold changes
 
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  dye-independent estimate of gene expression change upon
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  transcription factor deletion.
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  role: quantitative_measure
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+ - name: responsive
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+ dtype: float64
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+ description: >-
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+ abs(mean_norm_log2fc) `>` 1. Note that the authors do not have a threshold
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+ in their paper. They do use a zscore `>` 3 which they say is about a
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+ 1.58 FC. That yielded exceptionally few DE genes, so I reduced the value
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  ---
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  # Hughes 2006
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