---
license: cc-by-nc-4.0
tags:
- biology
- protein
- antibody
- VHH
configs:
- config_name: labelled
  data_files: "AVIDa-hTNFa.csv"
  default: true
- config_name: corpus
  data_files: "corpus-hTNFa.csv"
---

## AVIDa-hTNFa

AVIDa-hTNFa is an antigen-antibody interaction dataset produced from two alpacas immunized with human tumor necrosis factor alpha (TNFa) protein. This dataset includes labels indicating whether the VHH sequences are binders or non-binders to the wild type TNFa protein.

## Columns

**AVIDa-hTNFa.csv**

| Column          | Description                                                                       |
| --------------- | --------------------------------------------------------------------------------- |
| VHH_sequence    | Amino acid sequence of VHH                                                        |
| Ag_label        | Antigen Type                                                                      |
| label           | Binary label represented by 1 for the binding pair and 0 for the non-binding pair |
| subject_species | Species of the subject from which VHH was collected                               |
| subject_name    | Name of the subject from which VHH was collected                                  |
| subject_sex     | Sex of the subject from which VHH was collected                                   |

**antigen_sequences.csv**

| Column      | Description                    |
| ----------- | ------------------------------ |
| Ag_label    | Antigen Type                   |
| Ag_sequence | Amino acid sequence of antigen |

**corpus-hTNFa.csv**

| Column          | Description                                         |
| --------------- | --------------------------------------------------- |
| VHH_sequence    | Amino acid sequence of VHH                          |
| subject_species | Species of the subject from which VHH was collected |
| subject_name    | Name of the subject from which VHH was collected    |
| subject_sex     | Sex of the subject from which VHH was collected     |