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# Protein Sequences and Dynamic Properties for Training SeqDance and ESMDance
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This dataset contains **protein sequences, dynamic properties, and feature weights** used for training **SeqDance** and **ESMDance**, two **protein language models** designed to learn **protein dynamic properties**.
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the dynamicPDB dataset `dynamicpdb_seq.csv, feature_dynamicpdb.h5` was used as an independent testset, as these MD simulations used a different force field compared to those in the training set.
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### **Feature Weights**
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The weights for each feature in the training loss are based on the **standard deviation** of each feature. Please refer to our paper for further details.
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---
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license: cc-by-4.0
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language:
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- en
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---
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# Protein Sequences and Dynamic Properties for Training SeqDance and ESMDance
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This dataset contains **protein sequences, dynamic properties, and feature weights** used for training **SeqDance** and **ESMDance**, two **protein language models** designed to learn **protein dynamic properties**.
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the dynamicPDB dataset `dynamicpdb_seq.csv, feature_dynamicpdb.h5` was used as an independent testset, as these MD simulations used a different force field compared to those in the training set.
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### **Feature Weights**
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The weights for each feature in the training loss are based on the **standard deviation** of each feature. Please refer to our paper for further details.
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### **Citation**
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C. Hou,H. Zhao, & Y. Shen, Protein language models trained on biophysical dynamics inform mutation effects, Proc. Natl. Acad. Sci. U.S.A. 123 (4) e2530466123, https://doi.org/10.1073/pnas.2530466123 (2026).
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