row_id
string
series_id
string
timepoint_h
int64
host_model
string
drug
string
drug_conc_mg_L
float64
expected_drug_conc_mg_L
float64
conc_deviation
float64
egfr_ml_min_1p73
float64
expected_egfr_ml_min_1p73
float64
egfr_drop_vs_expected
float64
creatinine_mg_dL
float64
expected_creatinine_mg_dL
float64
creatinine_rise_vs_expected
float64
renal_coherence_index
float64
exposure_index
float64
stress_index
float64
later_severe_aki_flag
int64
assay_method
string
source_type
string
renal_clearance_decoupling_signal
int64
earliest_renal_clearance_decoupling
int64
notes
string
ABXHT002-TR-0001
S1
0
human_sim
vancomycin
12
12
0
95
95
0
0.9
0.9
0
0.9
0.1
0.1
0
pk_creat_egfr_panel
simulated
0
0
baseline
ABXHT002-TR-0002
S1
12
human_sim
vancomycin
14
14
0
92
92
0
0.95
0.95
0
0.88
0.85
0.9
0
pk_creat_egfr_panel
simulated
0
0
tracks expected
ABXHT002-TR-0003
S1
24
human_sim
vancomycin
14.5
14
0.5
80
90
10
1.2
1
0.2
0.35
0.9
0.9
0
pk_creat_egfr_panel
simulated
0
0
first decoupling
ABXHT002-TR-0004
S1
36
human_sim
vancomycin
15
14
1
78
90
12
1.3
1
0.3
0.3
0.9
0.9
0
pk_creat_egfr_panel
simulated
1
1
confirmed onset
ABXHT002-TR-0005
S1
72
human_sim
vancomycin
20
15
5
55
88
33
2.1
1.05
1.05
0.2
0.9
0.9
1
pk_creat_egfr_panel
simulated
1
0
severe later
ABXHT002-TR-0006
S2
0
human_sim
gentamicin
4
4
0
100
100
0
0.8
0.8
0
0.9
0.1
0.1
0
pk_creat_egfr_panel
simulated
0
0
baseline
ABXHT002-TR-0007
S2
24
human_sim
gentamicin
4
4
0
98
98
0
0.82
0.82
0
0.86
0.9
0.9
0
pk_creat_egfr_panel
simulated
0
0
stable
ABXHT002-TR-0008
S2
48
human_sim
gentamicin
4
4
0
97
97
0
0.83
0.83
0
0.84
0.9
0.9
0
pk_creat_egfr_panel
simulated
0
0
stable
ABXHT002-TR-0009
S3
0
human_sim
vancomycin
14
14
0
35
35
0
2.2
2.2
0
0.9
0.9
0.9
1
pk_creat_egfr_panel
simulated
0
0
baseline renal poor
ABXHT002-TR-0010
S4
0
human_sim
vancomycin
15
14
1
78
90
12
1.3
1
0.3
0.3
0.9
0.3
1
pk_creat_egfr_panel
simulated
0
0
stress low