row_id string | series_id string | timepoint_h int64 | host_model string | drug string | drug_conc_mg_L float64 | expected_drug_conc_mg_L float64 | conc_deviation float64 | egfr_ml_min_1p73 float64 | expected_egfr_ml_min_1p73 float64 | egfr_drop_vs_expected float64 | creatinine_mg_dL float64 | expected_creatinine_mg_dL float64 | creatinine_rise_vs_expected float64 | renal_coherence_index float64 | exposure_index float64 | stress_index float64 | later_severe_aki_flag int64 | assay_method string | source_type string | renal_clearance_decoupling_signal int64 | earliest_renal_clearance_decoupling int64 | notes string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABXHT002-TR-0001 | S1 | 0 | human_sim | vancomycin | 12 | 12 | 0 | 95 | 95 | 0 | 0.9 | 0.9 | 0 | 0.9 | 0.1 | 0.1 | 0 | pk_creat_egfr_panel | simulated | 0 | 0 | baseline |
ABXHT002-TR-0002 | S1 | 12 | human_sim | vancomycin | 14 | 14 | 0 | 92 | 92 | 0 | 0.95 | 0.95 | 0 | 0.88 | 0.85 | 0.9 | 0 | pk_creat_egfr_panel | simulated | 0 | 0 | tracks expected |
ABXHT002-TR-0003 | S1 | 24 | human_sim | vancomycin | 14.5 | 14 | 0.5 | 80 | 90 | 10 | 1.2 | 1 | 0.2 | 0.35 | 0.9 | 0.9 | 0 | pk_creat_egfr_panel | simulated | 0 | 0 | first decoupling |
ABXHT002-TR-0004 | S1 | 36 | human_sim | vancomycin | 15 | 14 | 1 | 78 | 90 | 12 | 1.3 | 1 | 0.3 | 0.3 | 0.9 | 0.9 | 0 | pk_creat_egfr_panel | simulated | 1 | 1 | confirmed onset |
ABXHT002-TR-0005 | S1 | 72 | human_sim | vancomycin | 20 | 15 | 5 | 55 | 88 | 33 | 2.1 | 1.05 | 1.05 | 0.2 | 0.9 | 0.9 | 1 | pk_creat_egfr_panel | simulated | 1 | 0 | severe later |
ABXHT002-TR-0006 | S2 | 0 | human_sim | gentamicin | 4 | 4 | 0 | 100 | 100 | 0 | 0.8 | 0.8 | 0 | 0.9 | 0.1 | 0.1 | 0 | pk_creat_egfr_panel | simulated | 0 | 0 | baseline |
ABXHT002-TR-0007 | S2 | 24 | human_sim | gentamicin | 4 | 4 | 0 | 98 | 98 | 0 | 0.82 | 0.82 | 0 | 0.86 | 0.9 | 0.9 | 0 | pk_creat_egfr_panel | simulated | 0 | 0 | stable |
ABXHT002-TR-0008 | S2 | 48 | human_sim | gentamicin | 4 | 4 | 0 | 97 | 97 | 0 | 0.83 | 0.83 | 0 | 0.84 | 0.9 | 0.9 | 0 | pk_creat_egfr_panel | simulated | 0 | 0 | stable |
ABXHT002-TR-0009 | S3 | 0 | human_sim | vancomycin | 14 | 14 | 0 | 35 | 35 | 0 | 2.2 | 2.2 | 0 | 0.9 | 0.9 | 0.9 | 1 | pk_creat_egfr_panel | simulated | 0 | 0 | baseline renal poor |
ABXHT002-TR-0010 | S4 | 0 | human_sim | vancomycin | 15 | 14 | 1 | 78 | 90 | 12 | 1.3 | 1 | 0.3 | 0.3 | 0.9 | 0.3 | 1 | pk_creat_egfr_panel | simulated | 0 | 0 | stress low |
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