sample_id,source_framework,target_framework,concept,source_definition,target_definition,claim,option_a,option_b,task,correct_option,required_note,required_keywords,axis,difficulty
CPFT-0001,Registry,Publication,Inclusion criteria,"Age 18–75","Age 18–65","Claim same enrolled population","Invalid correspondence, age range narrowed","Valid correspondence, minor edit","Judge correspondence and write note","A","State 18–75 vs 18–65 and flag narrowed eligibility","18–75|18–65|age|narrowed|eligibility",inclusion_criteria,2
CPFT-0002,Registry,SAP,Analysis set,"ITT includes all randomized","mITT excludes no-dose patients","Treat ITT and mITT as identical","Invalid correspondence, analysis set changed","Valid correspondence, mITT fully mapped","Judge correspondence and write note","A","State ITT vs mITT and require explicit exclusion mapping","ITT|mITT|exclude|no dose|mapping",analysis_set,3
CPFT-0003,Protocol,Publication,Exclusion criteria,"No prior anti-PD-1","Prior anti-PD-1 allowed in analysis","Assume criteria unchanged","Invalid correspondence, exposure rule changed","Valid correspondence, same rule","Judge correspondence and write note","A","State prior anti-PD-1 change and flag population drift","prior anti-PD-1|allowed|exposure|drift|criteria",exclusion_criteria,3
CPFT-0004,Protocol,SAP,Stratification factor,"Stratify by EGFR status","Stratify by EGFR and smoking","Assume same strata","Partial correspondence, strata expanded","Valid correspondence, unchanged","Judge correspondence and write note","A","State added smoking stratification and note comparability impact","EGFR|smoking|stratify|expanded|comparability",stratification,2
CPFT-0005,Registry,Publication,High-risk subgroup,"High risk = prior MI","High risk = prior MI or diabetes","Treat subgroup as same","Partial correspondence, definition broadened","Valid correspondence, same subgroup","Judge correspondence and write note","A","State MI-only vs MI-or-diabetes and flag broadened subgroup","MI|diabetes|high risk|broadened|definition",subgroup_definition,2
CPFT-0006,Protocol,Publication,Missing data handling,"All randomized included","Exclude patients missing baseline scan","Assume cohort unchanged","Invalid correspondence, exclusions added","Valid correspondence, same cohort","Judge correspondence and write note","A","State baseline scan exclusion and flag post-randomization selection","missing baseline|exclude|post-randomization|selection|cohort",missingness_selection,3
CPFT-0007,Registry,Publication,Enrollment geography,"Global sites","EU sites only in analysis","Treat as same population","Invalid correspondence, geography restricted","Valid correspondence, same sites","Judge correspondence and write note","A","State global vs EU-only and flag restricted external validity","global|EU only|geography|restricted|external validity",population_scope,3
CPFT-0008,Protocol,SAP,Per-protocol set,"Not defined","Per-protocol excludes major deviations","Report PP as primary without mapping","Invalid correspondence, primary set changed","Valid correspondence, PP secondary only","Judge correspondence and write note","A","State per-protocol introduced and require mapping from ITT","per-protocol|deviations|primary|mapping|ITT",analysis_set_shift,3
CPFT-0009,Registry,Publication,Run-in period,"No run-in","2-week placebo run-in excludes non-adherent","Treat as same enrolled group","Invalid correspondence, selection introduced","Valid correspondence, run-in documented and mapped","Judge correspondence and write note","A","State run-in selection and flag adherence-based exclusion","run-in|placebo|non-adherent|selection|exclude",selection_mechanism,3
CPFT-0010,Protocol,Publication,Substudy cohort,"All participants eligible","Only biomarker-positive included","Treat substudy results as trial-wide","Invalid correspondence, cohort restricted","Valid correspondence, restricted cohort stated","Judge correspondence and write note","A","State biomarker-positive restriction and block generalization","biomarker-positive|restricted|cohort|generalize|trial-wide",generalization,3