id,platform,compound_or_toxicant,dose_context,precursor_pattern_label,decoherence_onset_time,early_signature_set,affected_coupling_edges,observed_or_expected_damage_endpoints,collapse_dynamics_summary,collapse_topology_class,propagation_pathway,primary_failure_module,failure_horizon_estimate,reversibility_window,minimal_intervention_set,residual_risk_after_intervention,notes,constraints,gold_checklist
TCTM-T01,"multi-tissue organ-on-chip","acetaminophen","high; hepatotoxic range","pattern_alpha_hepatic_decoherence","t=10h","ROS rise; bile acid drift; clearance decouple; liver-only stress","liver-kidney clearance; liver-heart energetics","ALT proxy rise; ATP fall; inflammatory spillover","liver stress amplifies then spills to kidney; late systemic inflammation","","","","","","","","Model must output topology class, propagation pathway, primary module, horizon, reversibility window, minimal intervention set, residual risk","Under 280 words","topology+path+module+horizon+window+fix+risk"