id stringclasses 10 values | domain stringclasses 5 values | studied_cohort stringclasses 10 values | claimed_population stringclasses 10 values | evidence_excerpt stringclasses 10 values | cohort_profile stringclasses 10 values | claimed_population_profile stringclasses 10 values | boundary_violations stringclasses 10 values | required_population_disambiguation stringclasses 10 values | risk_if_overgeneralized stringclasses 10 values | constraints stringclasses 1 value | gold_checklist stringclasses 1 value |
|---|---|---|---|---|---|---|---|---|---|---|---|
PBI-001 | clinical_trial | Adults 40-65 with HFrEF, NYHA II-III, eGFR>45, no recent MI | All heart failure patients including elderly and HFpEF | Enrollment excluded HFpEF and severe CKD; age cap 65 | age 40-65; HFrEF only; moderate disease; kidney function preserved | all ages; HFrEF+HFpEF; broader comorbidity | HFpEF overreach; elderly overreach; CKD severe overreach | Was HFpEF studied. Any elderly subgroup. Any CKD subgroup. Any real-world registry validation. | wrong prescribing; adverse events in frail patients; false guideline strength | Under 220 words. | cohort+claimed+violations+questions |
PBI-002 | clinical_trial | Adults 18-55, BMI 20-30, no diabetes, no steroids | General adult population including obese and diabetic | Exclusions remove key real-world groups | healthy adults; non-obese; non-diabetic | includes obesity; includes diabetes; includes steroid users | obesity and diabetes overreach | Any diabetic subgroup. Any BMI>35 subgroup. Any interaction analysis. | harm in diabetics; misleading benefit claims | Under 220 words. | cohort+claimed+violations+questions |
PBI-003 | clinical_trial | Adults 30-70 with RA on stable methotrexate | All autoimmune disease patients | Study only RA and background therapy fixed | RA only; MTX background; age 30-70 | multiple autoimmune diseases; varied backgrounds | disease class overreach; background therapy overreach | Any trials in lupus or IBD. Any biologic background subgroup. | ineffective or harmful off-label use | Under 220 words. | cohort+claimed+violations+questions |
PBI-004 | press_release | Middle-aged adults; no pediatrics | Suitable for children and teens | No pediatric enrollment | no pediatrics; adult dosing only | pediatric dosing and safety implied | pediatric overreach | Any pediatric PK study. Any juvenile safety data. | pediatric adverse events; dosing errors | Under 220 words. | cohort+claimed+violations+questions |
PBI-005 | regulatory | Trial enrolled reduced EF only | Label claim implies preserved EF too | Population mismatch | HFrEF only | HFpEF implied | HFpEF boundary breach | Exact label language. Any HFpEF evidence base. | mislabeling; insurer coverage distortion | Under 220 words. | cohort+claimed+violations+questions |
PBI-006 | guideline | Two RCTs in hospital setting | Recommendation for community primary care | Setting differs | inpatient; monitored; short follow-up | outpatient; mixed adherence; long horizon | setting boundary breach | Any outpatient pragmatic trial. Any adherence sensitivity. | harms when monitoring absent | Under 220 words. | cohort+claimed+violations+questions |
PBI-007 | clinical_trial | Age 40-65 only | Claimed benefit for elderly 80+ | Age mismatch | 40-65 | 80+ | age boundary breach | Any frailty stratification. Any real-world data in 80+. | falls; renal events; drug interactions | Under 220 words. | cohort+claimed+violations+questions |
PBI-008 | clinical_trial | Single country, majority one ancestry | Claimed universal across ancestries | Demographic mismatch | single region; limited ancestry diversity | global populations; diverse ancestries | ancestry boundary breach | Any multi-region trial. Any PK differences by ancestry. | variable efficacy; safety signals missed | Under 220 words. | cohort+claimed+violations+questions |
PBI-009 | observational | Specialist center cohort only | Claimed general population effect | Referral bias | specialist; high severity; selected | general population | referral bias boundary breach | Any population-based replication. | false effect size; misallocation of resources | Under 220 words. | cohort+claimed+violations+questions |
PBI-010 | clinical_trial | Excluded pregnant people | Claim implies safe in pregnancy | Exclusion ignored | non-pregnant only | pregnancy included | pregnancy boundary breach | Any pregnancy registry. Any reproductive tox evidence. | fetal harm; legal risk | Under 220 words. | cohort+claimed+violations+questions |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.