Datasets:
Update dataset card: add schema, stats, citation, and Converge Bio about section
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README.md
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# UniClust30 (UniRef30)
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Complete [UniClust30 / UniRef30](https://uniclust.mmseqs.com/) dataset (release 2023_02) from the
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**Part of the [ConvergeBio Protein Database Collection](https://huggingface.co/collections/ConvergeBio/protein-database)**
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## Dataset Summary
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| **Clusters** | 36,293,491 |
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| **Shards** | 629 |
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## Schema
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Each row represents one
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| Column | Type | Description |
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|--------|------|-------------|
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# Stream without downloading everything
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ds = load_dataset("ConvergeBio/uniclust30", streaming=True)
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for row in ds["train"]:
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print(row["cluster_id"], row["
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break
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# Or load fully
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ds = load_dataset("ConvergeBio/uniclust30")
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```
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### Working with A3M alignments
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The `a3m` column contains the full multiple sequence alignment in [A3M format](https://github.com/soedinglab/hh-suite/wiki#a3m-format) (a compressed variant of FASTA). You can parse it directly or use HH-suite tools:
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```python
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row = next(iter(ds["train"]))
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lines = row["a3m"].split("\n")
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headers = [l for l in lines if l.startswith(">")]
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print(f"Cluster {row['cluster_id']}: {len(headers)} sequences in MSA")
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```
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## Data Processing
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- **Source:**
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- **Parsing:**
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- **Integrity:** xxHash-128 computed per sequence; A3M
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- **Validation:** Passed all tiers
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- **Format:** Sharded Parquet with zstd compression
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## Source & Citation
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UniClust30 is produced by the [
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> Mirdita M, von den Driesch L, Galiez C, Martin MJ,
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> "Uniclust databases of clustered and deeply annotated protein sequences and
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> *Nucleic Acids
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> [doi:10.1093/nar/gkw1081](https://doi.org/10.1093/nar/gkw1081)
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## License
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UniClust30 data is available under
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# UniClust30 (UniRef30)
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Complete [UniClust30 / UniRef30](https://uniclust.mmseqs.com/) dataset (release 2023_02) from the Söding Lab, converted from HH-suite A3M format to sharded Parquet. UniClust30 clusters UniProt sequences at 30% identity and includes precomputed multiple sequence alignments (MSAs) — widely used as input for protein structure prediction (AlphaFold, ColabFold) and protein language model pretraining.
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**Part of the [ConvergeBio Protein Database Collection](https://huggingface.co/collections/ConvergeBio/protein-database)** — see also [UniRef50](https://huggingface.co/datasets/ConvergeBio/uniref50), [UniRef90](https://huggingface.co/datasets/ConvergeBio/uniref90), and [UniRef100](https://huggingface.co/datasets/ConvergeBio/uniref100).
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## Dataset Summary
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| **Clusters** | 36,293,491 |
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| **Shards** | 629 |
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| **Release** | 2023_02 |
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| **Includes** | Precomputed A3M multiple sequence alignments per cluster |
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## Schema
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Each row represents one UniClust30 cluster with its representative sequence, MSA, and membership information.
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| Column | Type | Description |
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|--------|------|-------------|
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# Stream without downloading everything
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ds = load_dataset("ConvergeBio/uniclust30", streaming=True)
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for row in ds["train"]:
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print(row["cluster_id"], row["sequence_length"], row["num_aligned"])
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break
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# Or load fully
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ds = load_dataset("ConvergeBio/uniclust30")
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```
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## Data Processing
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- **Source:** HH-suite ffindex/ffdata A3M database and `uniref_mapping.tsv.gz` from [uniclust.mmseqs.com](https://uniclust.mmseqs.com/)
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- **Parsing:** Direct ffindex/ffdata binary reads; membership from mapping TSV
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- **Integrity:** xxHash-128 computed per sequence; A3M representative sequence verified against extracted sequence
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- **Validation:** Passed all tiers — schema conformance, zero null/empty sequences, xxHash roundtrip, A3M format checks, A3M–sequence consistency, member ID mapping verification, and field-by-field comparison against source ffindex/ffdata
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- **Format:** Sharded Parquet with zstd compression
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## Source & Citation
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UniClust30 is produced by the [Söding Lab](https://www.mpinat.mpg.de/soeding):
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> Mirdita M, von den Driesch L, Galiez C, Martin MJ, Söding J, Steinegger M.
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> "Uniclust databases of clustered and deeply annotated protein sequences and
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> alignments." *Nucleic Acids Res.* 45(D1):D170–D176 (2017).
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> [doi:10.1093/nar/gkw1081](https://doi.org/10.1093/nar/gkw1081)
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## About
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Built by [Converge Bio](https://converge-bio.com) — accelerating drug discovery with generative AI. Converge Bio develops foundation models for protein engineering, antibody design, and gene expression optimization, powering its computational lab products ConvergeAB, ConvergeGEO, and ConvergeCELL.
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## License
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UniClust30 data is available under
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[CC BY-SA 4.0](https://creativecommons.org/licenses/by-sa/4.0/).
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