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Background: Symptomatic uncomplicated diverticular disease can affect patients’ everyday routine. Considerable efforts have been made to identify clinical features that correlate to the severity of the disease. Unexpected intraoperative abscesses are reported in large retrospective series, showing how uncomplicated sym... |
An obligatory crossing-over event between the X and Y chromosomes in mammals occurs at each male meiosis within the 2.6 Mb of DNA defining the pseudoautosomal region (PAR). Genes located within or near the human PAR have homologous copies on the X and Y chromosomes, escape X inactivation and appear to be highly diverge... |
Introduction: Amblyopia is reduced visual acuity in one or both eyes due to abnormal visual development in early part of life. Purpose of this study was to evaluate and compare the retinal nerve fibre layer (RNFL) and central macular thickness (CMT) between amblyopic and fellow (normal) eyes using spectral-domain optic... |
Methods: This was a hospital based, cross-sectional comparative study conducted in the department of Ophthalmology, B.P. Koirala Lions Centre for Ophthalmic Studies (BPKLCOS), Institute of Medicine (IOM), Tribhuvan University Teaching Hospital (TUTH). All consecutive cases of age ≥5 years and ≤15 years diagnosed with u... |
Results: A total of 32 cases with unilateral amblyopia, 19 with hypermetropic anisometropic, 4 with myopic anisometropic and 9 with strabismic amblyopia were enrolled in the study. The mean age of presentation was 9.75±2.77 years. The mean CMT in amblyopic eyes (241±45.27 μm) was significantly greater than the normal f... |
Conclusions: The CMT was significantly greater in the amblyopic eyes than the normal fellow eyes. There was no significant difference in the RNFL thickness between the amblyopic and normal eyes.[Recent progress and future direction of neurodegenerative disease research]. |
Although the pathogenetic mechanisms underlying neurodegenerative diseases have been long elusive, recent progress in molecular neurogenetics and neurobiology has suggested that accumulation of misfolded protein leads to dysfunction and degeneration of neurons. Misfolded proteins have propensities to form fibrils terme... |
writer got little satisfaction from these things. Some troublesome editorial errors also exist. Among them, newspaper editor John Wheeler turns up as “Harry Wheeler” (118); the publication date of To Have and Have Not is recorded as 1938 (128); Venice’s Gritti Palace Hotel once appears as “Gritte” (152); and agent Lela... |
1. the laws that govern the assignment of words to positions in a hierarchical syntactic structure; 2. the laws that govern the assignment of words to more than one position in hierarchical syntactic structure (movement or chain formation); 3. the interface between syntactic structure (including movement) and semantic ... |
Soellner published on the interplay between allosteric and adenosine triphosphate (ATP)-competitive inhibitors of ABL kinase, showing that the latter preferably binds to different conformational states of ABL compared to allosteric agents that specifically target the ABL myristate pocket (STAMP) and deducing that ascim... |
According to a recent study by Van De Camp pointed out that online sales are expected to rise from $17 billion in 2005 to $18.4 billion in 2006 in China. Despite this spectacular annual growth of 8.2%, many web based businesses failed in recent years leading to the "dotcom bubble burst". With these changes, the busines... |
Most of the health problems in India are public health problems. Epidemiology education has not received sufficient attention so that clinicians can make evidence-based decisions, enabling them to identify valid research results, understand the data, and apply the research to their own practices. Knowledge of epidemiol... |
A one-dimensional self-consistent particle in cell/Monte Carlo method is used to study the local (at the laser impact region) and fast relaxation phenomena after laser-induced photodetachment in a strongly electronegative SiH(4)/H(2) rf discharge. The relaxation process of the local densities of the charged plasma spec... |
An online reinforcement learning algorithm is proposed in this paper to directly utilizes online data efficiently for continuous deterministic systems without system parameters. The dependence on some specific approximation structures is crucial to limit the wide application of online reinforcement learning algorithms.... |
Abstract The “classical” modeling of powder X-ray diffraction (XRD) patterns of lamellar structures, such as phyllosilicates, assumes that the samples are composed of “crystals” having various thickness and well-defined translations between layers. This model is able to describe the high-angle domain of XRD patterns bu... |
Purpose:To assess the prevalence of ocular, adnexal and orbital trauma resulting from various inciting agents presenting at three large centers located in different areas of Karachi, Pakistan.Method:Patients with ocular trauma were recruited at three centers over three months. Proforma was filled for every patient, an... |
Inhaled nitric oxide (iNO) therapy improves gas exchange and lowers pulmonary vascular resistance in neonates and children with diverse cardiac and pulmonary disorders. Recent multicenter studies have shown that iNO reduces the need for rescue therapy with extracorporeal membrane oxygenation in term neonates with sever... |
I describe an efficient, inexpensive, industry-standard computer system that is designed for word processing of surgical pathology reports as well as encoding in Systematized Nomenclature of Medicine (SNOMED) and data storage. This system is capable of maintaining a large database of patient information with coded diag... |
Low-temperature plasma treatment is a promising technology for particulate matter (PM). In this paper, the arrayed dielectric barrier discharge (DBD) plasma reactor for PM2.5 removal is investigated at atmospheric pressure. In order to reveal the interaction between experimental findings and simulation results, the equ... |
IMPORTANCE |
The prevalence and clinical burden of lymphedema is known to be increasing. Nevertheless, evidence-based comparative effectiveness data regarding lymphedema therapeutic interventions have been poor. |
OBJECTIVE |
To examine the impact of an advanced pneumatic compression device (APCD) on cutaneous and other clinical outcomes and health economic costs in a representative privately insured population of lymphedema patients. |
DESIGN, SETTING, AND PARTICIPANTS |
Retrospective analysis of a deidentified private insurance database from 2007 through 2013, and multivariate regression analysis comparing outcomes for the 12 months before and after APCD purchase, adjusting for baseline patient characteristics. Patients with lymphedema who received an APCD who were commercially insure... |
INTERVENTION |
Receipt of an APCD. |
MAIN OUTCOMES AND MEASURES |
Rates of cellulitis, use of lymphedema-related manual therapy, outpatient hospital visits, and inpatient hospitalizations. Lymphedema-related direct costs were measured for home health care, hospital outpatient care, office visits, emergency department use, and inpatient care. |
RESULTS |
The study sample included 718 patients (374 in the cancer cohort and 344 in the noncancer cohort). In both cohorts, use of an APCD was associated with similar reductions in adjusted rates of cellulitis episodes (from 21.1% to 4.5% in the cancer cohort and 28.8% to 7.3% in the noncancer cohort; P < .001 for both), lymph... |
CONCLUSIONS AND RELEVANCE |
The study found an association between significant reductions in episodes of cellulitis (cancer vs noncancer cohorts) and outpatient care and costs of APCD acquisition within a 1-year time frame in patients with both cancer-related and non-cancer-related lymphedema.The Military , Wealth and Strategic Redistribution |
Why do some developing world democracies redistribute too much at the expense of investment and output ("left-wing populism"), while others allow high levels of inequality to persist or even increase over time ("neo-liberalism")? Neither of these policies is consistent with a median voter who sets taxes by trading-o¤ d... |
Differently for what happened for the heart and the cardiovascular diseases, no data were available on the prevalence of the liver disorders in the general population. Based on these considerations we started planning a cohort study aimed to obtain data on how frequent liver disease was in the general population. Two c... |
The Asian corn borer, Ostrinia furnacalis (Guenée) (Lepidoptera: Crambidae), is the most important insect pest of maize in China. Despite the proven track record of biotech Bacillus thuringiensis (Bt) maize to provide an effective means to control lepidopteran pests such as the European corn borer Ostrinia nubilalis (H... |
We present an update on the Visible Light Laser Guidestar Experiments ViLLaGEs) taking place at the Lick Observatory. The goal of phase one of these experiments is to demonstrate the practical feasibility of using MEMS deformable mirrors in astronomical adaptive optics systems, including the use of open-loop wavefront ... |
We have been developing a web-based software tool named DDGEL [3] for analysis of two-dimensional (2-D) gel electrophoresis image data obtained by the RLGS (Restriction Landmark Genomic Scanning) method. The RLGS method has been developed in order to detect and analyze the genetic alterations by observing the entire ge... |
Sirtuin 5 is a class III histone deacetylase that, unlike its classification, mainly catalyzes desuccinylation and demanoylation reactions. It is an interesting drug target that we use here to test new ideas for calculating reaction pathways of large molecular systems such as enzymes. A major issue with most schemes (e... |
The mechanism of dipolar complexation involving Diethylamine and four alcohols namely Iso propanol, Hexan-1-ol, 2 Butoxy ethanol and 2 Ethyl hexan-1-ol in non-polar solvent Benzene medium was investigated from the dielectric measurements at a static frequency and at a temperature of 303 K. The dipole moment of the comp... |
Conventional Augmented Reality has used data gloves or markers for smooth interaction between objects and background. This causes inconvenience of use and lower immersion. To build up immersion in Augmented Reality, additional input devices must be removed. For this purpose, accurate recognition of space coordinates is... |
This paper attempts to address the similarities and differences between psychoanalytic psychotherapy and psychoanalysis as practice. Starting from the manifest technical points, which he dismisses as peripheral, the author reaches the position that he considers to be the fundamental area of contention, i.e. the tranfer... |
Drylands are diverse and dynamic ecosystems that have been occupied by humans throughout the Holocene. Nonetheless, drylands are often conceived of as marginal, rare, and inimical to human livelihoods. This Special Issue interrogates the interactions between humans and arid and aridifying environments to investigate ho... |
Apart from its classical role in bone and mineral metabolism, 1,25-dihydroxyvitamin D3 (1,25-vitamin D3) has recently been shown to affect cell growth and differentiation from a variety of tissues primarily not involved in mineral metabolism and to provide immunomodulatory functions. Findings in human mesangial cells i... |
PpsR from Rhodobacter sphaeroides is involved in the repression of photosystem gene expression. The PpsR protein was heterologously overexpressed and purified to homogeneity. Gel mobility shift assay showed that the purified PpsR has DNA-binding activity. SDS-PAGE analysis showed that some portions of PpsR were oxidize... |
Salmonella typhimurium S24 was isolated in September 1986 at Kaohsiung Medical College Hospital, Kaohsiung, Taiwan, from a patient suffering from gastroenteritis during an outbreak of salmonellosis. Two conjugative R-plasmids have been isolated from Escherichia coli K-12 14R525, which was mated with S. typhimurium S24.... |
Background: A 65-year-old woman presented with progressive walking disturbances and limping of the left leg. On clinical examination central paresis of the left leg was observed. The Babinski sign was positive on the left. Initially there were no sensory disturbances. EMG showed no evidence of a peripheral neuropathy. ... |
The molecular configuration and intermolecular arrangement of polycrystalline methoxycarbonylurea (MCU) has been studied by a combination of chemical editing, rotational echo double resonance (REDOR) spectroscopy and ab initio calculations. From the multispin IS(n) REDOR experiments several dipolar couplings were deter... |
Although α-synuclein is expressed primarily in neurons, it is a major component of oligodendroglial and astrocytic inclusions in several neurodegenerative diseases. Recent study has further demonstrated that α-synuclein is expressed in cultured rat oligodendrocytes. We determined whether α-synuclein might be expressed ... |
In recent years, and now especially with the arrival of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), there has been increased interest in understanding the role of bats in the dynamics of transmission and origin of this pandemic agent. To date, no systematic reviews have been published on this topi... |
Psychotherapy and Clinical Fellows responded to a survey that requested them to recommend books they thought were of substantial help in training the prospective clinician to do psychotherapy. Responses indicated that there was little agreement among clinicians with regard to which books are helpful. Also, a minority o... |
A computer-assisted music-learning system (CAMLS) has been developed to help the hearing impaired practice playing a musical melody. The music-learning performance is evaluated to test the usability of the system. This system can be a computer-supported learning tool for the hearing impaired to help them understand wha... |
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