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has been a tough yet stimulating year for security professionals-it started with the Aurora attacks and hasn't let up since then. There's a lot that can be said about working in this field, but it certainly can't be said that it's boring. As expected, predictions for next year don't bode well, but we're always ready fo... |
Primary mediastinal adenocarcinoma is rare, but its originating from a calcified nodule is even more unusual. We present herein a 55-year-old female with a superior mediastinal mass, first discovered 2 years prior that changed dramatically from its original appearance as a calcified nodule. The mass was completely rese... |
Genomic in situ hybridization (GISH), which is a modification of fluorescent in situ hybridization, has been widely used in the study of plants. It has become one of the most important techniques for molecular cytogenetics. GISH is a technique that allows distinguishing the genomes in a cell. With this technique, it is... |
We consider a class of quantum dissipative systems governed by a one parameter completely positive maps on a von-Neumann algebra. We introduce a notion of recurrent and metastable projections for the dynamics and prove that the unit operator can be decomposed into orthogonal projections where each projections are recur... |
BACKGROUND |
Neural tube defects are severe, common birth defects that result from failure of neural tube closure. They are considered to be a multifactorial disorder, and our knowledge of causal mechanisms remains limited. We hypothesized that abnormal DNA methylation occurs in NTD-affected fetuses. The correlations of global DNA ... |
METHODS |
A hospital-based case-control study was performed. Epidemiologic data, pathologic diagnosis, and methylenetetrahydrofolate reductase (MTHFR) genotype analysis were completed. Array comparative genomic hybridization was used to exclude cytogenetic abnormalities. Global DNA methylation statuses were determined for both b... |
RESULTS |
Sixty-five NTD-affected fetuses and 65 normal controls matched for gestational and maternal ages were collected. In brain tissue, global DNA methylation levels were significantly decreased in cases compared with controls (4.12 vs. 4.99%; p < 0.001). DNA hypomethylation (<4.35%) resulted in a significant 5.736-fold incr... |
CONCLUSIONS |
Global DNA hypomethylation in fetal brain tissue was associated with NTD-affected pregnancy. DNA methylation levels were correlated with NTD complexity. The MTHFR genotype contributed to global DNA hypomethylation. Birth Defects Research (Part A), 2010. (c) 2010 Wiley-Liss, Inc.Continuous Process Improvement and the Ri... |
In today's climate, every good manager should pay attention to the technology gap developing between the deployment of information assurance (IA) products and the technical capabilities of exploiters who can successfully attack an enterprise's information assets. The growing number of would-be hackers eager to infiltra... |
The driving intelligence of the virtual intelligent vehicle in the driving simulation system is crucial to the system's sense of reality and the reliability of the experiment. This paper focuses on the features and functionality of the virtual intelligent vehicle in driving simulation system. Intelligent vehicle should... |
Pulmonary hypertension is associated with pulmonary vascular remodelling, rendering the vessels unresponsive to vasodilators. An understanding of the mechanisms which cause this remodelling is required, which is likely to be linked to changes in vascular tone whether stimulated by hypoxia or other factors. One way to a... |
The purpose of this paper is to explore the concepts of state stewardship and international super-stewardship in public health from a philosophical point of view. The paper falls in 3 sections. The first section explores the origins of stewardship discourse in general and how the concept of stewardship entered discussi... |
In SW Amazon Craton, along the boundary between the Ventuari-Tapajos (1.9 to 1.8 Ga) and the Rio Negro-Juruena (1.8 to 1.55 Ga) provinces, an association of volcanic rocks and related epizonal granitic plutons crop out as a volcanic belt with more than 600 km long. This set of rocks, here called the Volcanic Domain (VD... |
In this work, based on whole rock geochemistry, and in U-Pb and Sm-Nd isotopic results we propose a geodynamic model that admit shifts in the tectonic regime through time and unifies the second and third interpretations above. We interpret the intermediate to acid, A-type, oxidized granitic and volcanic rocks from the ... |
The continental arc interpretation for the VD is supported by the following lines of evidence: (1) spatial arrangement of the VD in the shape of a volcanic belt; (2) the large volume of volcaniclastic deposits and related epizonal granitic intrusions; (3) variable chemical signatures ranging from subalkaline mafic com... |
A simple theory is described for the transverse susceptibility of an exchange-coupled ferromagnetic-antiferromagnetic pair. The theory is evaluated for parameters corresponding to the system Ni-NiO. The susceptibility as a function of the applied field shows large peaks at fields characteristic of the volumes of the tw... |
Nous avons decrive une simple theorie pour la susceptibilite transversale d'une paire ferromagnetique-antiferromagnetique accouplee par l'interaction d'echange. La theorie est evaluee pour les parametres correspondants au systeme Ni-NiO. La susceptibilite en fonction du champ applique montre des pics eleves pour certai... |
Abstract In this paper, we analyze the acquisition and tracking performance of signal using a tiered differential polyphase code as the secondary code. The Zadoff-Chu sequence is known to have a CAZAC (Constant Amplitude Zero Auto-Correlation) characteristics. The secondary code generated by differential encoding of th... |
Virtual environments (VEs) offer huge potential for a wide range of applications including the transfer of spatial knowledge from virtual spaces to real world places; beneficial in situations where it would be impractical, too expensive or dangerous, to acquire that knowledge from the real environment. Research has sho... |
Photocatalytic oxidation of ammonia in wastewater has been abundantly investigated in lab − scale, but there are still many issues to be solved towards practical application. Herein, we have immobilized Cu/TiO2 photocatalyst on different solid substrates in order to practically utilize and recycle the photocatalyst du... |
The MnGeTe2 compound crystallizes in a cubic structure without any phase transition and has great potential for enhancing the thermoelectric merit of MnGeTe2-based materials. In this work, Sb was used as an effective dopant to replace Ge sites in MnGeTe2 compounds. By optimizing the carrier concentration, excellent pow... |
Within linearized Poisson-Boltzmann theory, we study the disjoining pressure of two oppositely charged parallel objects (membranes and colloidal platelets) in a 1:1 electrolyte, with a focus on the effects of their finite thickness. This extension of the standard Gouy-Chapman model from an interacting pair of double la... |
UNLABELLED |
sGAL is a computer program designed to find pairs of sites suitable for introducing chemical cross-links into proteins. sGAL takes a protein structure file in PDB format as input, truncates each residue sequentially to its gamma side chain atom to mimic mutation to Cys, and calculates the exposed surface area of the ga... |
AVAILABILITY |
http://www.chem.utoronto.ca/staff/GAW/links.html; (Surface Racer is also required see: http://monte.biochem.wisc.edu/~tsodikov/surface.html).The bottom-up approach to molecular-level devices and machines. |
The macroscopic concepts of a device and a machine can be extended to the molecular level. Molecular-level devices and machines are constructed by a bottom-up approach. The atom-by-atom bottom-up approach is unrealistic from the chemical viewpoint. The bottom-up approach molecule-by-molecule following the guidelines of... |
The objective of this article is to present the design method of a hierarchical driver aid which is designed to guide the driver of a vehicle to perform parallel parking maneuver. The development philosophy of the system is based on biomimetic model where the designer of the model does not need to be aware of either ve... |
When the pretransplant sera of cadaver donor transplant patients were divided into 132 with anti-F(ab‘)2 (Fab) antibodies and 121 without anti-Fab antibodies, those patients with the antibodies had a 2-year graft survival rate of 59.7 ± 4.6% (±SE) as compared with 34.0 ± 5.0% (±SE) for those without antibodies (P > 0.0... |
The in vitro anti-Helicobacter pylori (H. pylori) activity of ebrotidine (N-[(E)-[[2-[[[2-[(diaminomethylene) amino]-4-thiazolyl]methyl]thio]ethyl]amino]methylene]-4-bromo- benzenesulfonamide, CAS 100981-43-9, FI-3542) versus ranitidine, and their effect on the susceptibility to the antimicrobial agents used in H. pylo... |
Background and Aims |
Rotundone is responsible for peppery aroma in wine. This note is not appreciated by all consumers, which indicates that rotundone might be considered as a taint above a certain concentration. The current study aimed at determining a consumer rejection threshold for rotundone in Duras red wine. |
Methods and Results |
Consumers (n = 62) received pairs of samples consisting of a base wine and the base wine spiked with an ascending concentration of rotundone and were asked to indicate which sample they preferred. Anosmic respondents detected through triangle tests represented 31% of the panellists. For these panellists, the wine spike... |
Conclusions |
The response of consumers to rotundone is complex, and peppery notes are perceived positively or in a neutral manner by most consumers with the exception of young panellists. |
Significance of the Study |
Our results may assist grape growers producing Duras and other cultivars, where rotundone makes a sensory contribution, to adapt their products to consumer profiles. They also open new fields of investigation into mechanisms involved in specific anosmia to rotundone.A Statistical Model to Compute the Effect of Agile Te... |
Agile methods promise to achieve high productivity and provide high-quality software. Agile software development is the most important model that has spread through the world of software development over the past decade. Software productivity measurement is essential in agile teams to increase the performance of Softwa... |
Although genetic distances are often assumed to be proportional to physical distances, chromosomal regions with unusually high (hotspots) or low (coldspots) levels of meiotic recombination have been described in a number of genetic systems. In general, the DNA sequences responsible for these effects have not been deter... |
The goal of this study was to investigate the performance of different feature types for voice quality classification using multiple classifiers. The study compared the COVAREP feature set; which included glottal source features, frequency warped cepstrum, and harmonic model features; against the mel-frequency cepstral... |
Combination of Fuzzy logic and Genetic Algorithm is becoming popular among researchers in the field. GFT (Genetic Fuzzimetric Technique) is of no exception which merges Fuzzy logic with genetic algorithm to achieve the optimization of the decision making process under uncertainty. Multivariable structure of any fuzzy r... |
We report on current profile evolution in EAST NBI driven plasmas where two neutral beams are injected, one during the current ramp phase and the second during flattop. At the end of the current ramp phase, it is found that a flat q profile with q0 ∼ 1 is achieved with low magnetic shear in the core. It is observed tha... |
Abstract This article argues that Adib Khan’s fiction challenges the orthodoxies of rigid cultural boundaries and dominator systems by creatively reconfiguring histories, landscapes and identities into forms of transcultural dialogue. Both Homecoming (2003) and Spiral Road (2007) tell the story of the disquieted lives ... |
The exact vacuum polarization 4-tensor in the presence of a static magnetic field is calculated by a method due to Svetozarova and Tsytovich (1962). The Hermitian part of the tensor is explicitly renormalized and the anti-Hermitian part of the tensor is found to be finite and gauge invariant. An alternative method for ... |
When the financial crisis struck in 2007–2008, there was a brief, 2-year flurry of active governmental attempts to provide stimulus to the economy to prevent a recession from turning into a full-blown depression, coupled with active efforts to support the financial system such that it did not ‘meltdown’ and exacerbate ... |
We describe a generalization of stochastic transduction grammars to be able to model continuous values, the first models to natively handle continuous-valued musical events such as microtones while still gaining the advantages of STGs for describing complex structural, hierarchically compositional inter-part relationsh... |
Exposing an extruded corn snack, an extruded biodegradable packing material, carrots, and wood chip cork to relative humidity conditions ranging from 29.5 to 97.5% changed their moisture content and affected the respective internal structures. The extruded corn snack and extruded biodegradable packing material specimen... |
Theory of Computation (TOC) seeks to understand computational phenomena, be it natural, man-made or imaginative. TOC is an independent scientific discipline of fundamental importance. Its intrinsic goals (those which were achieved, those which are yet to be achieved, and those which are yet to be defined) transcend the... |
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