--- license: cc-by-sa-4.0 task_categories: - token-classification tags: - genomics - bioinformatics - dna - biology - gene-prediction - science - huggingscience - genome-annotation - token-classification pretty_name: Gene Finding size_categories: - 1K Genomic Dataset designed for evaluating and benchmarking gene prediction algorithms. The source of the dataset is the [GENCODE 2021 Project](https://watermark02.silverchair.com/gkaa1087.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA1MwggNPBgkqhkiG9w0BBwagggNAMIIDPAIBADCCAzUGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM9pw3GLRMhtZvcWWIAgEQgIIDBtP1R80Xq87yoSgbVEPGW20YHDCG4gdw2DhHcDlxsJPiqIM_JPa9033FbiH4JY5ypci9GSXWA73Gp9ZX_Nsl7YKApfYEhCBO2s9RfUV_EV2bk6HdDKQBxa4_UHPNyRjfrWGNhGWV-oukuc4v8Zt2nkoH14o0OrMC0VaJ2gj3OTQGBLZUC7ZpY-kfEPT71VoeHhb53RRYx6JlA4qk_kXS06N4b9xRkKHtFPO1qW2l9tFShy8VUKXtPYi7B49qAYginTIXgmVeRUGXbBodVevB3mODTGPesZdi6er0P64BPCY-hrips1CuGZiCe1J4nBWLxso3eMiKoEgJAy-_O0w_2Mr6KW9qoyjgz0KEotZhZNE_XZOXqYhwcLbkOTCkXppLKKf7ukEewBjWqZUPjWbmfbK1brtBmOqob2eimPXAWC1cBwF6MU6hHlq9uKIXXF4_SC2SaCR4ptlpIsbDtRXzf1H7Z-3JDx_rxwP5IU8Dw5jcUmbvWOLf8Ke7xvERCYvX9kLkbMjuGjGztZSSvQWnonxAui2LN8OPAaVSME9xkEf6j8Xsp61lssP6LcY--Len8gmk61MypGNjND0pQMQW3bleiJ5QMLFfHYad_1vDvKNyv0kzSfRlCq407hEE7jilOcd8lrhdbJzGKmZUy1LQCHpTDaDKhO-4MFH5ds-3N_3wL5tICqpQ_-13QivNJKNX0XC9cT3EG2N73IyS5_lZs7obdzbN_4gUcLgqrHYMDO0RxTEz3WIO_FTnSgjK9N9Kf7-3uZubxOYz6nMCGzzADd45lafim943u1DcPSCkOL4mKpfzKvRduf_VEdIq8S-cC-oxiw_leOduiXHT005C4UQXGMBOWam0TUtQ6Qu2pcLincTCd-ysoExjnuGzgTvicKbla2Pl9BXQXfIz48mBMaA0gXYW-jWxNnV2W973b8kXaR_PBEIjUdOqJJkWaMl6XIy96x6sD48YluDRQhaNvRLCv55pzmoUmuaiiIjD6LC0RyrdZSosJbo7uv76rTJptZHpupOEWg) which provides high accuracy genen and transcript annotations for human and mouse genomes supported by experiemntal data. This makes it a foundational resource that supports genome biology and clinical genomics applications. - **Curated by:** Multiple People - **Funded by [optional]:** [More Information Needed] - **Shared by [optional]:** DNA-LLM - **Language(s) (NLP):** NA - **License:** MIT ### Dataset Sources [optional] - **Paper [optional]:** [GENCODE 2021 Paper](https://huggingface.co/datasets/DNA-LLM/gene_finding_benchmark_v1/new/main?filename=README.md) ## Uses ### Direct Use - **Gene prediction algorithm benchmarking:** Evaluating the performance of computational methods for identifying genes in DNA sequences - **Machine learning model training:** Training models for genomic sequence analysis and gene identification ### Out-of-Scope Use - **Clinical diagnostics:** Not suitable for real-time clinical decision making - **Medical applications:** Not intended for direct medical diagnosis or treatment ## Dataset Structure - **seq:** DNA nucleotide sequence (A, T, G, C) - the input genomic sequence - **labels:** Gene annotation labels for the sequence - indicating gene structure elements ## Dataset Creation ### Curation Rationale The dataset was created to address the need for standardized benchmarking in computational genomics, specifically: - **Lack of standardized benchmarks:** Gene prediction algorithms lacked consistent evaluation metrics - **Quality annotation requirements:** Need for high-quality, experimentally validated gene annotations - **Research reproducibility:** Providing a common dataset for comparing different approaches - **Algorithm development:** Supporting the development of more accurate gene finding methods ### Source Data #### Data Collection and Processing - Genomic sequences sourced from the GENCODE 2021 annotation database #### Who are the source data producers? - **GENCODE consortium:** International collaboration of research institutions ### Annotations [optional] #### Annotation process [More Information Needed] #### Who are the annotators? [More Information Needed] #### Personal and Sensitive Information [More Information Needed] ## Bias, Risks, and Limitations [More Information Needed] ### Recommendations Users should be made aware of the risks, biases and limitations of the dataset. More information needed for further recommendations. ## Citation **BibTeX:** ```bibtex @article{frankish2021gencode, title={GENCODE 2021}, author={Frankish, Adam and Diekhans, Mark and Jungreis, Irwin and Lagarde, Julien and Loveland, Jane E and Mudge, Jonathan M and Sisu, Cristina and Wright, James C and Armstrong, Joel and Barnes, If and others}, journal={Nucleic acids research}, volume={49}, number={D1}, pages={D916--D923}, year={2021}, publisher={Oxford University Press} } ``` **APA:** Frankish, A., Diekhans, M., Jungreis, I., Lagarde, J., Loveland, J. E., Mudge, J. M., Sisu, C., Wright, J. C., Armstrong, J., Barnes, I., & others. (2021). GENCODE 2021. *Nucleic acids research*, *49*(D1), D916-D923. ## Glossary [optional] [More Information Needed] ## More Information [optional] [More Information Needed] ## Dataset Card Authors [optional] [More Information Needed] ## Dataset Card Contact [More Information Needed]