--- license: cc-by-4.0 task_categories: - image-classification tags: - medical - pathology - whole-slide-imaging - cancer-detection --- # CPath Preprocessed Patch for E2E Training This dataset is used for training E2E CPath model, presented in [Revisiting End-to-End Learning with Slide-level Supervision in Computational Pathology](https://huggingface.co/papers/2506.02408), NeurIPS 2025. **Code:** [https://github.com/DearCaat/E2E-WSI-ABMILX](https://github.com/DearCaat/E2E-WSI-ABMILX) ## Sample Usage This dataset provides preprocessed whole-slide image (WSI) patches in LMDB format. Below is an example of how to load data from an LMDB dataset. ```python import lmdb import torch import pickle from datasets.utils import imfrombytes # Ensure this utility function is correctly referenced slide_name = "xxxx" # Example slide name path_to_lmdb = "YOUR_PATH_TO_LMDB_FILE" # e.g., "/path/to/my_dataset_256_level0.lmdb" # Open LMDB dataset env = lmdb.open(path_to_lmdb, subdir=False, readonly=True, lock=False, readahead=False, meminit=False, map_size=100 * (1024**3)) with env.begin(write=False) as txn: # Get patch count for the slide pn_dict = pickle.loads(txn.get(b'__pn__')) if slide_name not in pn_dict: raise ValueError(f"Slide ID {slide_name} not found in LMDB metadata.") num_patches = pn_dict[slide_name] # Generate patch IDs patch_ids = [f"{slide_name}-{i}" for i in range(num_patches)] # Allocate memory for patches (adjust dimensions and dtype as needed) # Assuming patches are 224x224, 3 channels, and will be normalized later patches_tensor = torch.empty((len(patch_ids), 3, 224, 224), dtype=torch.float32) # Load and decode data into torch.tensor for i, key_str in enumerate(patch_ids): patch_bytes = txn.get(key_str.encode('ascii')) if patch_bytes is None: print(f"Warning: Key {key_str} not found in LMDB.") continue # Assuming the stored value is pickled image bytes img_array = imfrombytes(pickle.loads(patch_bytes).tobytes()) # Or .tobytes() if it's already bytes patches_tensor[i] = torch.from_numpy(img_array.transpose(2, 0, 1)) # HWC to CHW # Normalize the data (example using ImageNet stats) # Ensure values are in [0, 255] before this normalization if they aren't already mean = torch.tensor([0.485, 0.456, 0.406]).view((1, 3, 1, 1)) * 255.0 std = torch.tensor([0.229, 0.224, 0.225]).view((1, 3, 1, 1)) * 255.0 # If your patches_tensor is already in [0,1] range, remove * 255.0 from mean/std # If your patches_tensor is uint8 [0,255], convert to float first: patches_tensor.float() patches_tensor = (patches_tensor.float() - mean) / std env.close() ``` ## Citation **BibTeX:** ``` @misc{tang2025revisitingendtoendlearningslidelevel, title={Revisiting End-to-End Learning with Slide-level Supervision in Computational Pathology}, author={Wenhao Tang and Rong Qin and Heng Fang and Fengtao Zhou and Hao Chen and Xiang Li and Ming-Ming Cheng}, year={2025}, eprint={2506.02408}, archivePrefix={arXiv}, primaryClass={cs.CV}, url={https://arxiv.org/abs/2506.02408}, } ```