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---
license: odc-by
task_categories:
- feature-extraction
tags:
- chemistry
- smiles
- cheminformatics
pretty_name: Augmented Canonical PubChem 10M
size_categories:
- 10M<n<100M
---

# PubChem 10M - Augmented SMILES Dataset  

This dataset is derived from the original PubChem 10M and has been canonicalized using RDKit (2024.9.4) to ensure structural consistency.  

To enhance molecular diversity, 33% of the dataset was randomly sampled and augmented using RDKit’s `Chem.MolToRandomSmilesVect` function, following an approach similar to NVIDIA’s *molmim* method for SMILES augmentation.  

### Dataset Overview:  
- **Source:** PubChem 10M  
- **Canonicalization:** RDKit (2024.9.4)  
- **Augmentation:** Random SMILES generation for 33% of the original dataset