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Scintimetric evaluation of complications after femoral neck fractures
Management of Hip Fractures in the Elderly
The primary surgical approach to the femoral neck fracture should be one with the lowest mortality and morbidity. Internal fixation appears to be the safe and logical approach for most of the reducible intracapsular fractures. Careful follow-up of these patients then is important. 85Sr scintimetry is a simple and accur...
12,647
0
Acquired melanocytic nevi in Egyptian patients: a clinicopathological study
Reconstruction After Skin Cancer
INTRODUCTION: Melanocytic nevi (MN) are the most important simulants of melanoma. Although acquired nevi are usually clinically stable, they may show abnormal clinical behavior. This study assessed the histological changes and prognosis of acquired MN with changing clinical behavior in Egyptian patients.METHODS: The st...
61,545
0
Spinal anaesthesia in young patients using a 29-gauge needle: technical considerations and an evaluation of postoperative complaints compared with general anaesthesia
Surgical Management of Osteoarthritis of the Knee CPG
One hundred patients aged 18-49 yr, undergoing elective arthroscopy of the knee joint, were allocated randomly to either spinal anaesthesia using a 29-gauge spinal needle or general anaesthesia. Dural puncture was considered difficult in 18% of the patients receiving spinal anaesthesia. In three patients (6%) it was ne...
26,484
0
Radiostereometric analysis in measurements of migration and inducible micromotion in intra-articular distal radius fractures treated with a volar plate
Distal Radius Fractures
OBJECTIVES: This study examined the use of radiostereometric analysis (RSA) in the assessment of fixation stability and healing characteristics in intra-articular fractures of the distal radius treated with a volar locking plate. DESIGN: Prospective cohort study. SETTING: University hospital. PATIENTS: Fifteen patients...
118,013
0
Limited clinical utility of a self-evaluating risk assessment scale for postmenopausal osteoporosis: lack of predictive value of lifestyle-related factors
Management of Hip Fractures in the Elderly
The aim of this study was to assess the efficiency of a self-administered questionnaire to identify subjects with postmenopausal osteoporosis in the setting of first line medical care. A sample of 300 postmenopausal women completed the questionnaire based on 18 items. Bone mineral density at the lumbar spine (BMD-L), t...
3,729
1
Minimally invasive sliding hip screw insertion technique
Management of Hip Fractures in the Elderly
Sliding hip screws (SHS) are commonly used for fixation of extra-capsular hip fractures, and there is increasing use of minimally invasive methods of insertion of such devices. We describe a case series of 579 consecutive patients operated on by the senior author using such a technique. Data were collected prospectivel...
14,062
0
Articular fractures of the distal part of the humerus
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
BACKGROUND: The purpose of this retrospective study was to identify the patterns of distal humeral articular fractures and to analyze the results of open reduction and internal fixation of these injuries. METHODS: The cases of twenty-one patients with an articular fracture of the distal part of the humerus were reviewe...
22,950
0
Surgical versus conservative interventions for treating fractures of the middle third of the clavicle
DoD SSI (Surgical Site Infections)
BACKGROUND: Clavicle fractures are common, accounting for 2.6% to 4% of all fractures. Eighty per cent of clavicle fractures are located in the middle third of the clavicle. Although treatment of these fractures is usually non-surgical, displaced clavicle fractures may be considered for surgical treatment because of th...
150,334
0
Alzheimer's disease and risk of hip fracture: a meta-analysis study
Management of Hip Fractures in the Elderly
BACKGROUND: Alzheimer's disease (AD) is the most common cause of dementia in the elderly population. Growing evidence supports that AD patients are at high risk for hip fracture, but the issue remains questionable. The purpose of the present study is to perform a meta-analysis to explore the association between AD and ...
11,774
1
A survey of antibiotic use in dentistry
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
BACKGROUND: Antibiotics are important in the management and prophylaxis of infection in patients at risk of experiencing microbial disease. As a result of the increase in antimicrobial resistance, the authors conducted a survey to assess current antibiotic use in dental practice. METHODS: The authors mailed a two-page,...
21,810
0
Cemented all polyethylene tibial insert unicompartimental knee arthroplasty: a long term follow-up study
Surgical Management of Osteoarthritis of the Knee CPG
Unicompartimental knee arthroplasty outcome is sometimes compared to total knee arthroplasty but various implant parameters might greatly influence this outcome. The objectives of this study were to report the results of a consecutive series of 172 all-polyethylene unicompartmental knee arthroplasties (UKAs) and to det...
35,911
0
Lower-extremity kinetic response to activity program dosing in older adults
Management of Hip Fractures in the Elderly
The purpose of this investigation was to determine the effects of two doses of a weighted vest on acute lower-extremity gait kinetics in older adults. Peak ankle, knee, and hip net joint moments were quantified in 56 men and women volunteers (73.8 +/- 6.9 years old) enrolled in a 6-month physical activity study. At the...
9,505
0
Femoral fractures in adolescents: a comparison of four methods of fixation
DoD SSI (Surgical Site Infections)
BACKGROUND: The optimal management of femoral fractures in adolescents is controversial. This study was performed to compare the results and complications of four methods of fixation and to determine the factors related to those complications. METHODS: We conducted a retrospective cohort study of 194 diaphyseal femoral...
148,706
0
The influence of patellofemoral degenerative changes on the outcome of the unicompartmental knee replacement
Surgical Management of Osteoarthritis of the Knee CPG
Introduction: Unicompartmental knee arthroplasty (UKA) is a recognized procedure for treatment of medial compartment osteoarthritis. Patellofemoral (PF) joint degeneration is widely considered to be a contraindication to medial unicompartmental knee replacement. We examined the validity of this preconception using info...
27,491
0
The Barrel Vault Tibial Osteotomy of Maquet for Medial Compartment Arthritis of the Knee
OAK 3 - Non-arthroplasty tx of OAK
The barrel vault tibial osteotomy performed for knee varus osteoarthritis avoids the complications of the opening wedge osteotomy and minimizes the potential complications of the lateral closing wedge osteotomy. It allows correction of large varus deformities in knee medial compartment osteoarthritis.
112,673
0
Nonsteroid antiinflammatory drugs and tamoxifen for desmoid tumors and carcinoma of the stomach
MSTS 2018 - Femur Mets and MM
The results of treatment of desmoid tumor patients with nonsteroid antiinflammatory drugs alone or in combination with tamoxifen are described. Tumor growth was inhibited in six of seven patients. Nonsteroid antiinflammatory drugs administered along with 5-fluorouracil and cyclophosphamide and other inhibitors of T-sup...
81,762
0
Lateral trochanteric pain following total hip arthroplasty: radiographic assessment of altered biomechanics as a potential aetiology
AAHKS (2) Corticosteroids
INTRODUCTION: Lateral trochanteric pain (LTP) complicates up to 17% of cases of total hip arthroplasty (THA). Studies have refuted underlying trochanteric bursitis. Restoration of the femoral offset and reproduction of the natural femoral centre of rotation are important in successful arthroplasty. LTP is believed to b...
84,675
0
Flexion space configuration in total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Equal resection of the posterior femoral condyles combined with a 90(degrees) tibial resection results in a trapezoidal flexion space. Two groups of patients were studied; in one group, the flexion space was allowed to remain trapezoidal, whereas in the other group, the anteroposterior femoral resections were externall...
31,405
0
Recovery time and patient satisfaction in ambulatory knee arthroscopy: Prospective study comparing three anaesthetic methods
Surgical Management of Osteoarthritis of the Knee CPG
The aim of this study was to compare recovery time and satisfaction of patients operated under two anaesthetic techniques. A randomised-controlled trial that enrolled ASA I-II patients submitted to ambulatory knee arthroscopy was designed. Patients included were randomly assigned to one of the three study groups: gener...
28,822
0
Osteoporotic Fracture: 2015 Position Statement of the Korean Society for Bone and Mineral Research
Pediatric Supracondylar Humerus Fracture 2020 Review
Osteoporotic fractures are one of the most common causes of disability and a major contributor to medical care costs worldwide. Prior osteoporotic fracture at any site is one of the strongest risk factors for a new fracture, which occurs very soon after the first fracture. Bone mineral density (BMD) scan, a conventiona...
141,666
0
Ibandronate for the treatment of hypercalcemia or nephrocalcinosis in patients with multiple myeloma and acute renal failure: Case reports
MSTS 2018 - Femur Mets and MM
Multiple myeloma disrupts calcium homeostasis by a variety of mechanisms, including bone destruction and resorption. This causes hypercalcemia. When left untreated, hypercalcemia leads to nephrocalcinosis, impairment of kidney function, and eventually renal failure. Some degree of renal dysfunction is common in myeloma...
81,010
0
Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFbeta1) gene in knee and hip osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
INTRODUCTION: The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFbeta1 polymorphisms in knee and hip osteoarthritis (OA). METHODS: We conducted a case-control study of Caucasian men and women aged 45 to 86 years from Nottingham, United Kingdom (Gen...
109,675
1
Posterior-stabilized versus cruciate-retaining total knee arthroplasty: Balancing the gap
Surgical Management of Osteoarthritis of the Knee CPG
A prospective, randomized, double-blind trial was carried out to compare cruciate-retaining (CR) and posterior-stabilized (PS) total knee arthroplasties (TKAs). A total of 40 knees were randomized to receive either a NexGen CR (Zimmer, Warsaw, IN) or a Legacy PS (Zimmer, Warsaw, IN) TKA. All knees were implanted with i...
38,330
1
Revision of infected hip replacement. Two-stage procedure with a temporary gentamicin spacer
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
We revised 5 infected totally-replaced hips in 2 stages. At the first operation a gentamicin-loaded modelled cement spacer was inserted, and the definitive prosthesis was inserted 3-8 weeks later. 9-24 months after the last operation, there was a recurrent infection in 1 case. 2 of the patients could walk in the interv...
22,002
0
Pain threshold correlates with functional scores in osteoarthritis patients
Surgical Management of Osteoarthritis of the Knee CPG
Background and purpose - Pain sensitization may be one of the reasons for persistent pain after technically successful joint replacement. We analyzed how pain sensitization, as measured by quantitative sensory testing, relates preoperatively to joint function in patients with osteoarthritis (OA) scheduled for joint rep...
36,534
0
Foreseeable pharmaceutical repair of age-related extracellular damage
Panniculectomy & Abdominoplasty CPG
Various molecular and cellular alterations to our tissues accumulate throughout life as intrinsic side-effects of metabolism. These alterations are initially harmless, but some, which we may term "damage", are pathogenic when sufficiently abundant. The slowness of their accumulation explains why decline of tissue and o...
123,975
0
Body mass index and risk of adverse cardiac events in elderly patients with hip fracture: a population-based study
Management of Hip Fractures in the Elderly
OBJECTIVES: To determine whether obesity affects cardiac complications after hip fracture repair. DESIGN: A population-based historical study using data from the Rochester Epidemiology Project. SETTING: Olmsted County, Minnesota. PARTICIPANTS: All urgent hip fracture repairs between 1988 and 2002. MEASUREMENTS: Body ma...
752
0
Recurrent hemarthrosis following a total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
The case of a recurrent hemarthrosis of a total knee arthroplasty after the sixth postoperative month is described. Because of disabling pain, the patient underwent an explorative arthrotomy 18 months after implantation of the total knee arthroplasty. A hypertrophied vascular mass of synovium was discovered in the late...
31,463
0
The use of a closed expandable prosthesis for pediatric sarcomas
DoD SSI (Surgical Site Infections)
PURPOSE: The purpose of this paper is to review our experience with a non-invasive expandable prosthesis for skeletally immature patients following limb-salvage for malignant tumors about the knee. MATERIALS & METHODS: Between 1998 and 2002, Repiphysis prostheses (Wright Medical Technology, Memphis, Tenn.) were implant...
147,329
0
Alterations in nitric oxide synthase isoforms in acute lower limb ischemia and reperfusion
Surgical Management of Osteoarthritis of the Knee CPG
Alterations in nitric oxide synthase (NOS) are implicated in ischemia and ischemia-reperfusion injury. Changes in the 3 NOS isoforms in human skeletal muscle subjected to acute ischemia and reperfusion were studied. Muscle biopsies were taken from patients undergoing total knee replacement. Distribution of the specific...
30,646
0
Condylar total knee arthroplasty after failed proximal tibial osteotomy
Surgical Management of Osteoarthritis of the Knee CPG
Data were collected retrospectively on thirty-five patients who had a failed osteotomy of the proximal part of the tibia for unicompartmental osteoarthrosis of the knee that was treated with a cruciate condylar, total condylar, kinematic condylar, or cemented porous-coated anatomical total knee prosthesis. The patients...
33,476
0
Use of aromatase inhibitors in breast carcinoma
MSTS 2018 - Femur Mets and MM
Aromatase, a cytochrome P-450 enzyme that catalyzes the conversion of androgens to estrogens, is the major mechanism of estrogen synthesis in the post-menopausal woman. We review some of the recent scientific advances which shed light on the biologic significance, physiology, expression and regulation of aromatase in b...
80,546
0
The pattern of bone marrow oedema on MRI in osteonecrosis of the femoral head
Management of Hip Fractures in the Elderly
It has been suggested that transient osteoporosis or the bone marrow oedema syndrome (BMOS) may be the initial phase of osteonecrosis of the femoral head (ONFH) and that there may be a common pathophysiology. In this study, we have assessed the MR images of 200 consecutive patients with ONFH in respect of the BMO patte...
6,203
0
Surgical treatment of subtrochanteric fractures of the femur: biomechanical aspects
Management of Hip Fractures in the Elderly
The internal fixation of subtrochanteric fractures of the femur must meet precise mechanical requirements in order to be capable of resisting the considerable bending stresses acting on this part of the body. On the basis of the results obtained in ninety two fractures treated surgically with various fixation devices, ...
12,588
1
Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis
Management of Hip Fractures in the Elderly
BACKGROUND: Patients taking oral anticoagulants with an international normalized ratio (INR) greater than 4.0 are at increased risk for bleeding. We performed a meta-analysis to determine the effectiveness of phytonadione (vitamin K) in treating excessive anticoagulation. METHODS: The MEDLINE, EMBASE, and Cochrane Libr...
14,234
0
The outcome of failed knee arthrodesis following total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
After failure of total knee arthroplasty, arthrodesis was attempted in 120 cases, and unsuccessful in 25 (21%). Failure of arthrodesis was defined as nonunion persisting one year after arthrodesis or reoperation to obtain union. The number of attempts at arthrodesis ranged from one to four. The most frequent reasons fo...
33,460
0
Multimodal analgesia for hip arthroplasty
AAHKS (2) Corticosteroids
Multimodal analgesia incorporates the use of analgesic adjuncts with different mechanisms of action to enhance postoperative pain management. Acetaminophen, anti-inflammatories, and gabapentinoids provide effective analgesia while reducing opioid requirements and opioid-related side effects. Intrathecal morphine and pe...
85,779
0
Impact of patellar height on unicompartment knee arthroplasty: Does patella baja lead to an inferior outcome?
Surgical Management of Osteoarthritis of the Knee CPG
Background Though a number of series with long-term results have been published, there is still a paucity of literature on the role of patellar height after unicompartment knee arthroplasty (UKA). The present study was conducted with a hypothesis that patella baja may lead to a poor outcome at follow-up.Materials and m...
26,165
0
Humeral shaft fractures secondary to hand grenade throwing
Pediatric Supracondylar Humerus Fracture 2020 Review
A series of five cases were presented in which similar fractures of the shaft of the humerus occurred during the hand grenade throwing activity during the military education. All the fractures were in the 1/3 distal humeral shaft, and butterfly fragments were accompanying in two soldiers. All the fractures healed witho...
142,184
0
Pelvic trauma: What are the predictors of mortality and cardiac, venous thrombo-embolic and infectious complications following injury?
DoD SSI (Surgical Site Infections)
INTRODUCTION: This study sought to determine risk factors that influence mortality, cardiac events, venous thrombo-embolic disease (VTED), and infection following fractures of the pelvis and/or acetabulum. METHODS: The 2008 National Sample Program (NSP) of the National Trauma Databank was queried to identify all patien...
146,426
0
5-Year experience of highly cross-linked polyethylene in cemented and uncemented sockets: Two randomized studies using radiostereometric analysis
Management of Hip Fractures in the Elderly
Background: Laboratory tests and early clinical studies have shown that highly cross-linked polyethylene (PE) markedly improves wear resistance compared to conventional PE. We evaluated this type of PE in two randomized clinical studies using radiostereometric analysis (RSA). The 2- and 3-year follow-up of these studie...
1,450
0
Liposomal nanomedicines in the treatment of prostate cancer
MSTS 2018 - Femur Mets and MM
Prostate cancer is the most common cancer type and the second leading cause of death from cancer in males. In most cases, no curative treatment options are available for metastatic castration-resistant prostate cancer as these tumors are highly resistant to chemotherapy. Targeted drug delivery, using liposomal drug del...
79,225
0
Clinical imaging diagnosis of implant materials for breast augmentation
Panniculectomy & Abdominoplasty CPG
BACKGROUND: The ingredients of substances implanted for breast augmentation sometimes remain unknown due to lack of information from patients. Significant clinical problems sometimes necessitate removal and reconstruction. Thus, preoperative diagnostic imaging to identify the ingredients of implants may improve the tre...
124,021
0
Hyaluronans: is clinical effectiveness dependent on molecular weight?
Surgical Management of Osteoarthritis of the Knee CPG
The original rationale for viscosupplementation with hyaluronans was fluid replacement, suggesting that the most viscous materials (eg, those of highest molecular weight [MW]) would provide the most clinical benefits. However, it has become clear that mechanisms of action for osteoarthritis pain management are not only...
30,596
1
Abnormal preoperative MRI does not correlate with failure of UKA
Surgical Management of Osteoarthritis of the Knee CPG
Modern indications for medial mobile-bearing unicompartmental knee arthroplasty (UKA) include a normal lateral compartment, minimal patellofemoral disease, and a ligamentously stable knee. Radiographs and intraoperative inspection can determine the appropriateness of UKA. Magnetic resonance imaging (MRI) interpretation...
37,851
0
The Mark Coventry Award: in vivo knee forces during recreation and exercise after knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
Knee forces directly affect arthroplasty component survivorship, wear of articular bearing surfaces, and integrity of the bone-implant interface. It is not known which activities generate forces within a range that is physiologically desirable but not high enough to jeopardize the survivorship of the prosthetic compone...
35,810
0
Effects of long-term intravenous ibandronate therapy on skeletal-related events, survival, and bone resorption markers in patients with advanced multiple myeloma
MSTS 2018 - Femur Mets and MM
PURPOSE: Bisphosphonates have been found to reduce the incidence of skeletal-related events (SREs) in patients with multiple myeloma. This is the first double-blind, randomized, placebo-controlled study to assess the efficacy of ibandronate, a third-generation amino-bisphosphonate, in preventing SREs in advanced-stage ...
83,544
0
Anti-inflammatory and anti-arthritic effects of the ethanolic extract of Aralia continentalis Kitag. in IL-1beta-stimulated human fibroblast-like synoviocytes and rodent models of polyarthritis and nociception
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Blocking the formation and invasive growth of pannus and its secretion of inflammatory cytokines and MMPs is important for treating rheumatoid arthritis. HYPOTHESIS/PURPOSE: Anti-arthritic activity of Aralia continentalis Kitag., an oriental herbal medicine, and the underlying mechanisms involved were inves...
102,172
0
Hip and knee replacement after longstanding hip arthrodesis
Surgical Management of Osteoarthritis of the Knee CPG
This study determined whether patients with severe knee disease below a hip arthrodesis can be treated successfully with total knee replacement alone or whether such patients require total hip arthroplasty followed by knee replacement. Eighteen patients who had hip arthrodesis for a mean of 33 years underwent total hip...
34,069
0
Single stage correction of gynecomastia: Liposuction & glandular excision
Panniculectomy & Abdominoplasty CPG
Objective: To determine the frequency of complications after single stage correction of gynecomastia, along with level of satisfaction in patients and surgeon 4 weeks post operatively Study Design: Prospective cohort study. Place and Duration of Study: This study was conducted at the Department of Plastic Surgery, Liaq...
125,706
0
Comparison of "hematoma block" versus "wrist block" anesthesia in the treatment of fifth metacarpal fracture
Distal Radius Fractures
INTERVENTION: Group A (hematoma block anesthesia): barbotage injection of the lidocaine 2% (3�5 ml) without epinephrine in hematoma site. Group B (wrist block anesthesia): after detecting landmarks with the help of a nerve locator, following shots will be injected respectively: 5�7 ml of lidocaine 2% without epinep...
117,728
0
Association between beta-blocker use and fracture risk: the Dubbo Osteoporosis Epidemiology Study
Management of Hip Fractures in the Elderly
INTRODUCTION: In animal model, mice treated with beta-blockers (BB) had increased bone mass. In humans, high bone mass is associated with reduce fracture risk. The present study sought to test the hypothesis that BB use is associated with reduced fracture risk. MATERIALS AND METHODS: Data from 3488 participants (1285 m...
11,614
0
New technique for humerus shaft fracture retrograde intramedullary nailing
Distal Radius Fractures
Humeral shaft fracture intramedullary nailing is less invasive than plates and screws. Antegrade technique has postoperative shoulder pain, increased rehab time, and frequent reoperation for rod removal. Published retrograde technique is not collinear with the shaft, has insertion site fractures (5% to 15%), and radial...
118,072
0
Ipsilateral femoral autograft reconstruction after resection of a pelvic tumor
MSTS 2018 - Femur Mets and MM
Background: Reconstruction of bone afterthe resection of a pelvic tumor is challenging. The purpose of the present study was to evaluate the use of the ipsilateral femur as the graft material for reconstruction. Methods: We performed a retrospective review of thirteen patients with a malignant pelvic lesion who underwe...
76,623
0
Shear-enhanced oral microbial adhesion
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Shear-enhanced adhesion, although not observed for fimbria-mediated adhesion of oral Actinomyces spp., was noted for Hsa-mediated adhesion of Streptococcus gordonii to sialic acid-containing receptors, an interaction implicated in the pathogenesis of infective endocarditis
17,740
0
The role of regional anesthesia in patient outcome: orthopedic surgery
Surgical Management of Osteoarthritis of the Knee CPG
Outcome is defined as "a change in a patient's health status that can be attributed to antecedent health care." Postoperative pain is a major concern after orthopedic limb surgery. Indeed, pain is exacerbated with motion, particularly after shoulder and knee surgery. From moderate at rest, pain becomes most severe duri...
28,811
0
Percutaneous fixation of adult Humerus with Titanium elastic nails
MSTS 2022 - Metastatic Disease of the Humerus
Objective: To study the results of treatment of fractures of shaft of Humerus using percutaneous Titanium Nails. Methodology: This is a quasi-experimental, prospective, interventional, study of 30 clinical cases that were operated with retrograde, per cutaneous elastic Titanium nails for treatment of diaphyseal fractur...
155,034
0
Magnetic resonance imaging: a cost-effective alternative to bone scintigraphy in the evaluation of patients with suspected hip fractures
HipFx Supplemental Cost Analysis
OBJECTIVE: To evaluate the cost-effectiveness of magnetic resonance imaging (MRI) compared with radionuclide bone scan in the evaluation of patients with clinically suspected hip fractures. DESIGN: The medical records of all patients who had been seen in the emergency room over a 4 1/2 year period with a clinically sus...
52,584
1
Single-institution outcome experience using AlloDerm(R) as temporary coverage or definitive reconstruction for cutaneous and soft tissue malignancy defects
Reconstruction After Skin Cancer
Definitive reconstruction after excision of cutaneous and soft tissue malignancies is sometimes limited as a result of lack of native tissue coverage options, patient comorbidities, or pending permanent margin analysis. Acellular dermis (AlloDerm(R)) reconstruction offers an excellent coverage alternative in these situ...
61,790
0
Exercise and NSAIDs: effect on muscle protein synthesis in patients with knee osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
PURPOSE: The purpose of this study was to determine muscle and tendon protein fractional synthesis rates (FSR) at rest and after a one�legged kicking exercise in patients with knee osteoarthritis (OA) receiving either placebo or nonsteroidal anti�inflammatory drugs (NSAIDs). METHODS: Twenty patients with knee OA (5...
104,920
0
Hyperbaric oxygen therapy as an adjuvant to standard therapy in the treatment of diabetic foot ulcers
DoD SSI (Surgical Site Infections)
Background and Aims: Chronic diabetic foot ulcers pose a major problem because of associated limb threatening complications. The aim of the present study was to evaluate the efficacy of hyperbaric oxygen therapy (HBOT) as an adjuvant to standard therapy for treatment of diabetic foot ulcers. Material and Methods: A tot...
147,882
0
Treatment of trochanteric fractures with Ender rods
Management of Hip Fractures in the Elderly
The technical aspects of Ender's method in the treatment of trochanteric fractures are described. Problems and complications encountered with this method and their prevention and treatment are discussed. Intraoperative and postoperative problems are subdivided into those in the hip area and around the knee joint, such ...
11,921
0
Radiographic Predictors of DRUJ Instability with Distal Radius Fractures
Distal Radius Fractures
Because the distal radioulnar joint (DRUJ) is an inherently unstable joint, the diagnosis and treatment of DRUJ instability is often difficult in a clinical hand surgery practice. Several soft tissue stabilizers are recognized, of which the deep limbs of the radioulnar ligament are primary stabilizers. This article dis...
121,075
0
Viscosupplementation in haemophilic arthropathy: a long-term follow-up study
OAK 3 - Non-arthroplasty tx of OAK
Haemophilic arthropathy is the most common clinical manifestation of haemophilia, secondary to recurrent haemarthroses and chronic synovitis. Modern bleeding-preventing drugs have limited significantly the incidence of severe arthropathy, and primary approach is usually conservative. Use of intra-articular injections o...
100,774
0
Subdural empyema after tooth extraction in which Capnocytophaga species was isolated
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
We describe a patient with meningitis and a subdural empyema arising from an infection after teeth extraction in which Capnocytophaga species was detected. The patient was a 54-y-old man without any underlying diseases. A computerized tomography scan showed a subdural empyema 21 d after the extraction
21,194
0
Nutritional assessment of residents in long-term care facilities (LTCFs): recommendations of the task force on nutrition and ageing of the IAGG European region and the IANA
HipFx Supplemental Cost Analysis
Unintentional weight loss and Undernutrition are major problems among older people living in Long-Term Care Facilities (LTCF). Undernutrition manifests in LTCF particularly as weight loss and low Body Mass Index (BMI) and is associated with increased morbidity and mortality as well as with functional decline. There are...
51,686
0
Arthroscopic management of osteoarthritis of the knee
Surgical Management of Osteoarthritis of the Knee CPG
Recent advances in instrumentation and a growing understanding of the pathophysiology of osteoarthritis have led to increased use of arthroscopy for the management of degenerative arthritis of the knee. Techniques include lavage and debridement, abrasion arthroplasty, subchondral penetration procedures (drilling and mi...
34,857
0
Carpal wedge osteotomy for the arthrogrypotic wrist
DOD - Acute Comp Syndrome CPG
The upper limbs of the child with the amyoplasia form of arthrogryposis are typically internally rotated at the shoulders, extended at the elbows, and flexed and deviated ulnarly at the wrists. This position results in an obligatory crossed-limb pattern of bimanual use, as neither hand is sufficiently strong or agile t...
63,846
0
The assessment and management of the stiff elbow
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Posttraumatic loss of elbow motion can cause substantial disability, limiting the ability to put one's hand in the volume of a sphere in space. Although a number of conditions can lead to loss of motion, a greater understanding of the functional anatomy of the elbow has led to advances in surgical management. Elbow sti...
22,944
0
Radial head fractures--an update
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Radial head fractures are the most common fractures occurring around the elbow. Although radial head fractures can occur in isolation, associated fractures and ligament injuries are common. Assembling the clinical presentation, physical examination, and imaging into an effective treatment plan can be challenging. The c...
23,805
0
The treatment of unstable ankle fractures in patients over eighty years of age
DoD SSI (Surgical Site Infections)
BACKGROUND: The current study examined the outcomes of operative treatment of unstable ankle fractures in patients at least 80 years old at the time of injury. METHODS: Of 2,682 patients who presented for treatment of ankle fractures, 17 patients met the study criteria. These patients had open reduction and internal fi...
147,213
0
Novel Pre-Surgery Exercise-Conditioning in Patients Waiting for Total Knee Arthroplasty (TKA)
OAK 3 - Non-arthroplasty tx of OAK
Total knee arthroplasty (TKA) is the treatment of choice for patients suffering from severe pain and functional limitation caused by osteoarthritis (OA) of the knee joint's surfaces (Magee et al. 2009). Within the UK, over 60,000 TKA surgeries are registered yearly (NJR 2015), making TKA one of the most common surgerie...
106,064
0
Dichloromethylene-diphosphonate in the treatment of osteolytic metastases
MSTS 2018 - Femur Mets and MM
Dichloromethylene diphosphonate (Clodronate) is very effective against osteoclasts. We studied its effects on calcium balance in patients with malignant osteolytic lesions. Ten normocalcemic patients with advanced metastatic bone disease or myeloma were evaluated in a baseline 20Î?Ã?Ã?day calcium balance and kinetic st...
80,766
1
Results and outcomes after operative treatment of high-energy tibial plafond fractures
DoD SSI (Surgical Site Infections)
BACKGROUND: The purposes of this study were to evaluate the clinical and radiographic results and the functional outcomes after operative treatment of tibial plafond fractures treated with internal or external fixation. METHODS: A retrospective review identified 76 patients with 79 fractures (OTA 43-B or 43-C) of the t...
151,839
0
Cathepsin D non-proteolytically induces proliferation and migration in human omental microvascular endothelial cells via activation of the ERK1/2 and PI3K/AKT pathways
MSTS 2018 - Femur Mets and MM
Epithelial ovarian cancer (EOC) frequently metastasises to the omentum, a process that requires pro-angiogenic activation of human omental microvascular endothelial cells (HOMECs) by tumour-secreted factors. We have previously shown that ovarian cancer cells secrete a range of factors that induce pro-angiogenic respons...
80,261
1
Comparison of negative pressure wound therapy (NPWT) &conventional wound dressings in the open fracture wounds
DoD SSI (Surgical Site Infections)
OBJECTIVE: Successful closure is a primary step of treatment in open fracture wounds. Delayed healing or complications can lead to increased treatment duration, costs and disability rates. The aim of this study was to compare Negative Pressure Wound Therapy (NPWT) and conventional wound dressings in patients with open ...
152,074
0
Denosumab: The era of targeted therapies in bone metastatic diseases
MSTS 2018 - Femur Mets and MM
This system constituted of the Receptor Activator of nuclear Factor-kB Ligand (RANKL), the Receptor Activator of Nuclear Factor-kB (RANK) and by the decoy Receptor Osteoprotegerin (OPG) plays a central role in bone resorption. Denosumab (AMG 162) is an investigational fully human monoclonal antibody with a high affinit...
80,870
0
Reducing fatal opioid overdose: Prevention, treatment and harm reduction strategies
DOD - Acute Comp Syndrome CPG
The opioid overdose epidemic is a major threat to the publicâ??s health, resulting in the development and implementation of a variety of strategies to reduce fatal overdose [1-3]. Many strategies are focused on primary prevention and increased access to effective treatment, although the past decade has seen an exponent...
64,365
0
Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): A concise update
MSTS 2018 - Femur Mets and MM
Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a severe complication seen most frequently in patients on intravenous bisphosphonates treatment for malignant diseases. High potency bisphosphonates are generally implicated and risk factors also include dental extractions. Prevention is of paramount importanc...
82,584
0
Bisphosphonates and osteonecrosis of the jaw: a retrospective study
MSTS 2018 - Femur Mets and MM
OBJECTIVE: To assess the prevalence of osteonecrosis of the jaw (ONJ) in patients receiving bisphosphonate therapy and in those who were bisphosphonate naive. METHODS: We undertook a retrospective review of medical records of patients at the New York Harbor Health Care System from 1999 through 2004. Charts were selecte...
82,642
0
Bone mass and subsequent risk of hip fracture
Management of Hip Fractures in the Elderly
We examined prospectively the associations of bone density and bone dimensions with risk of hip fracture using data from the first National Health and Nutrition Examination Survey and its three follow-up studies. A cohort of 1,489 white women age 45 years or older who received detailed medical examinations in the basel...
4,895
0
Multimodal analgesia after total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND: Perioperative pain management is the focus in total knee arthroplasty. Looking for a safe and effective analgesic way has become one of the important tasks of the surgeons. OBJECTIVE: To compare the analgesia and rehabilitation effect of the epidural analgesia and the femoral nerve analgesia after total kne...
28,443
0
The posterior cruciate ligament in total knee surgery: Save, sacrifice, or substitute?
Surgical Management of Osteoarthritis of the Knee CPG
To determine the role of the posterior cruciate ligament in total knee arthroplasty, 242 consecutive primary total knee arthroplasties were included in 1 of 3 sequential groups. Group I included 77 Press Fit Condylar total knee replacements in which the posterior cruciate ligament was completely released from its tibia...
31,398
0
Evidence for central sensitization in patients with osteoarthritis pain: A systematic literature review
OAK 3 - Non-arthroplasty tx of OAK
Hyperexcitability of the central nervous system (CNS) has been suggested to play an important role in the chronic pain experienced by osteoarthritis (OA) patients. A systematic review following PRISMA guidelines was performed to evaluate the existing evidence from the literature related to the presence of central sensi...
111,495
0
Biphasic anti-osteoclastic action of intravenous alendronate therapy in multiple myeloma bone disease
MSTS 2018 - Femur Mets and MM
Multiple myeloma is a malignancy of plasma cells with osteolytic bone destruction. Bisphosphonates inhibit osteoclast activity and are widely used for the treatment of myeloma bone disease. We analyzed the changes in urinary cross-linked N-telopeptides of collagen (u-NTx) and urinary calcium (u-Ca) after bisphosphonate...
79,157
0
Strategies for treating HIV-related lipodystrophy
Panniculectomy & Abdominoplasty CPG
HIV-related lipodystrophy has emerged as one of the most prevalent problems for patients with HIV, since this infection can now be seen as a chronic disease. Despite its growing importance, crucial issues such as aetiopathogenesis, diagnosis, prevention and therapy remain largely unknown and unexplored. Current evidenc...
123,490
0
[Minimally invasive total knee arthroplasty and navigation - a logical combination?]
Surgical Management of Osteoarthritis of the Knee CPG
The minimally invasive approach has been recommended for total knee arthroplasty by many surgeons and by industry in recent years, and patients now also expect it. The definition of a minimally invasive procedure is still the subject of some controversy. Some authors limit the length of the skin incision to 14 cm, whil...
31,135
0
External fixation and delayed unreamed intramedullary interlocking nailing of open fractures of Tibia. (A protocol)
DoD SSI (Surgical Site Infections)
Between June 2001 and Aug 2003, 27 open fractures of the Tibial shaft were treated with debridement and provisional external fixation, followed by delayed soft closure and subsequent interlocking nailing without reaming. There were 11(39%) grade-I fractures and 17(61%) grade-II fractures. All the fractures were the res...
149,668
0
New screening system for unruptured cerebral aneurysms--combination of an expert system and DSA examination
Upper Eyelid and Brow Surgery
We have designed a screening system to diagnose unruptured aneurysms, including the use of digital subtraction angiography (DSA). We surveyed 115 patients who had undergone clipping procedures after subarachnoid hemorrhage (SAH) and questioned them with regard to the subjective symptoms. Sixty-eight of 92 patients who ...
65,707
0
Extra-oral endosseous craniofacial implants: current status and future developments
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
The published experience of extra-oral endosseous craniofacial implants (EOECIs) is reviewed. The definition of osseointegration, concept of success, the relative merit of one- or two-stage implant placement, EOECI design and control of peri-abutment skin infection are discussed. A plea is made for more consistent and ...
16,864
0
Treatment of homonymous visual field defects
Upper Eyelid and Brow Surgery
OPINION STATEMENT: A clinical presentation of a retrochiasmal or homonymous visual field defect (HVFD) usually represents a permanent visual impairment. The visual and functional ramifications of HVFD will vary by patient. Comprehensive care-the clinical evaluation and consideration for treatment of HVFD-includes visio...
66,727
0
Prevention of bone loss by vitamin D supplementation in elderly women: a randomized double-blind trial
Management of Hip Fractures in the Elderly
The purpose of the study was to determine the effect of vitamin D supplementation on bone turnover and bone loss in elderly women. Three hundred forty-eight women, ages 70 yr and older, were randomized to receive 400 IU vitamin D3 per day (n = 177) or placebo (n = 171), double-blind, for a period of 2 yr. Main outcome ...
8,100
1
A locked hip screw-intramedullary nail (cephalomedullary nail) for the treatment of fractures of the proximal part of the femur combined with fractures of the femoral shaft
MSTS 2018 - Femur Mets and MM
Twenty-seven patients with complex femoral fractures (combined shaft and proximal femoral fractures) were treated with a modified Grosse-Kempf slotted locking nail (cephalomedullary nail), wherein two screws were inserted in the hip. Four types of complex, multifocal femoral fractures were represented in the series. El...
84,368
0
Chemokine receptors as specific anti-inflammatory targets in peripheral nerves
MSTS 2018 - Femur Mets and MM
Chemokines are the initial mediators of leukocyte migration across concentration gradients in vitro and to sites of inflammation in vivo. Chemokines signal via specific seven-transmembrane spanning G-protein coupled receptors (GPCRs). About 50 chemokine ligands and 18 receptors have been identified to date, and several...
81,659
0
Liposuction gives complete reduction of chronic large arm lymphedema after breast cancer
Panniculectomy & Abdominoplasty CPG
About one-third of all women treated for breast cancer develop arm lymphedema. In addition to the worry of the cancer itself, the swollen and heavy arm is both a physical and a psychosocial handicap for the patients. Previous surgical and conservative treatments have not always given satisfactory and permanent results,...
123,394
0
Physiological closure of the physeal plate of the distal radius: An MRI analysis
Distal Radius Fractures
To have knowledge of the physiological closure of a particular physeal plate is necessary to understand fractures close to the end of growth (transitional fractures). Most frequent fractures involve the distal radius in adolescents. However, there are no systematic investigations on the topic of growth plate closure co...
117,355
1
Cemented versus uncemented hemiarthroplasty for intracapsular hip fractures: A randomised controlled trial in 400 patients
Management of Hip Fractures in the Elderly
We undertook a prospective randomised controlled trial involving 400 patients with a displaced intracapsular fracture of the hip to determine whether there was any difference in outcome between treatment with a cemented Thompson hemiarthroplasty and an uncemented Austin-Moore prosthesis. The surviving patients were fol...
15,364
0
Total ankle arthroplasty: indications, results, and biomechanical rationale
Surgical Management of Osteoarthritis of the Knee CPG
Total ankle replacement was developed in the 1970s after the success of total hip and knee arthroplasty. The goal of total ankle arthroplasty is to decrease pain and improve function in the lower limb. Ideally, to be superior to an arthrodesis, the ankle replacement should provide the patient with good patterns of join...
30,369
0
Systemic biochemical markers of joint metabolism and inflammation in relation to radiographic parameters and pain of the knee: Data from CHECK, a cohort of early-osteoarthritis subjects
OAK 3 - Non-arthroplasty tx of OAK
Objective: To investigate associations of biochemical markers of joint metabolism and inflammation with minimum joint space width (JSW) and osteophyte area (OP area) of knees showing no or doubtful radiographic osteoarthritis (OA) and to investigate whether these differed between painful and non-painful knees. Design: ...
111,831
0
Age-related changes in visual pseudoneglect
Upper Eyelid and Brow Surgery
Pseudoneglect is a slight but consistent leftward attentional bias commonly observed in healthy young populations, purportedly explained by right hemispheric dominance. It has been suggested that normal aging might be associated with a decline of the right hemisphere. According to this hypothesis, a few studies have sh...
66,976
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