taskB.jsonl

{"id": "q_001", "task": "evidencebased_qa", "question": "How did the bifurcation study and intermediate-lesion study differ in lesion type, stenosis definition, and FFR/acquisition requirements?", "required_slots": 2, "slot_A": ["doc7b681e429c95_chunk000004"], "slot_B": ["docd7cb86d8211b_chunk000004"], "slot_nuggets": {"slot_A": ["The bifurcation study focused on bifurcation lesions.", "Bifurcation lesions required a side branch stenosis greater than 40% by visual estimation.", "FFR was measured in the main vessel before revascularization or in the side branch if no side-branch stent was implanted."], "slot_B": ["The intermediate-lesion study focused on de novo intermediate lesions.", "Intermediate lesions had 40% to 70% diameter stenosis by visual estimation.", "The intermediate-lesion study required nitroglycerine before acquisition and at least one projection during hyperemia."]}}
{"id": "q_002", "task": "evidencebased_qa", "question": "What graphics/display setup is required for the QFR server machine compared with the QFR client machine?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000009"], "slot_B": ["doceb909d6b9ee1_chunk000010"], "slot_nuggets": {"slot_A": ["The QFR server machine does not require a dedicated graphics card.", "The QFR server machine does not require a display monitor."], "slot_B": ["The QFR client application runs in a web browser.", "The QFR client should be used on a screen with the size of a desktop computer."]}}
{"id": "q_003", "task": "evidencebased_qa", "question": "How can d(QFR)/ds help the user interpret a QFR result, and how is it shown in the software?", "required_slots": 2, "slot_A": ["doc639a7e988eae_chunk000009"], "slot_B": ["doceb909d6b9ee1_chunk000037"], "slot_nuggets": {"slot_A": ["d(QFR)/ds shows where the QFR value changes most along the target vessel.", "This indicates the location of the biggest pressure drop."], "slot_B": ["The Physiology tab shows a QFR diagram.", "The QFR diagram shows both QFR values and d(QFR)/ds values across the target vessel.", "The index marker can be used to inspect the QFR and d(QFR)/ds values at a vessel position."]}}
{"id": "q_004", "task": "evidencebased_qa", "question": "How does coronary dominance change the territory supplied by the LCx, and how is coronary dominance defined?", "required_slots": 2, "slot_A": ["doccb0fce7c3072_chunk000003"], "slot_B": ["doccb0fce7c3072_chunk000004"], "slot_nuggets": {"slot_A": ["The LCx normally supplies approximately 15–25% of the left ventricle.", "When the LCx is dominant, it supplies approximately 40–50% of the left ventricle."], "slot_B": ["Coronary dominance can be defined by the artery that reaches the crux of the heart and gives off the PDA.", "A definition that allows codominance also considers whether the artery gives off the PDA and a large posterolateral branch."]}}
{"id": "q_005", "task": "evidencebased_qa", "question": "What is the difference between QFR image input requirements, practical acquisition guidelines, and technical limitations?", "required_slots": 3, "slot_A": ["doceb909d6b9ee1_chunk000013"], "slot_B": ["doceb909d6b9ee1_chunk000014"], "slot_C": ["doceb909d6b9ee1_chunk000004", "doc6e7afe84fe31_chunk000004"], "slot_nuggets": {"slot_A": ["Valid QFR input images must be DICOM XA grayscale images.", "Valid QFR input images must have square pixels, isocenter calibration data, fixed angulations, and at least five image frames."], "slot_B": ["QFR acquisition should use two target-vessel acquisitions from different angles.", "The two acquisitions should be at least 25 degrees apart, with 35 to 50 degrees being optimal.", "The procedure should use nitroglycerin, sufficient frame rate, suitable catheter size, and brisk contrast injection."], "slot_C": ["QFR measurements can be inaccurate with too much vessel overlap or foreshortening.", "QFR measurements can be inaccurate when no nitroglycerin has been administered.", "QFR measurements can be inaccurate in vessels with retrograde filling."]}}
{"id": "q_006", "task": "evidencebased_qa", "question": "In the Contours step, how can the user correct an incorrect pathline and incorrect vessel contours, and how can wrongly placed support points be deleted?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000031"], "slot_B": ["doceb909d6b9ee1_chunk000032"], "slot_nuggets": {"slot_A": ["Drag the incorrect pathline to the correct position to create a support point.", "Add or move pathline support points if more correction is needed.", "Right-click a pathline support point to delete it.", "Correct the pathline before correcting the contours."], "slot_B": ["Drag the incorrect contour to the correct vessel edge to create a contour support point.", "Add or move contour support points if more correction is needed.", "Right-click a contour support point to delete it."]}}
{"id": "q_007", "task": "evidencebased_qa", "question": "In the Results step, how can the user identify the most significant lesion, and how do highlighted and comparative table modes support lesion comparison?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000036"], "slot_B": ["doceb909d6b9ee1_chunk000039"], "slot_nuggets": {"slot_A": ["The angiogram viewports show target vessel contours and detected lesions as graphical overlays.", "The most significant lesion is automatically selected and highlighted based on the highest Delta QFR value.", "The 3D View shows the reconstructed target vessel color-coded by QFR values."], "slot_B": ["Highlighted mode shows the results of only the selected lesion.", "Comparative mode shows the results of all lesions in one overview.", "In comparative mode, the selected lesion is visually distinguished by different font color and size."]}}
{"id": "q_008", "task": "evidencebased_qa", "question": "What is QFR intended to be used for, and what responsibility remains when QFR results are used for diagnosis or treatment guidance?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000002", "doc6e7afe84fe31_chunk000002"], "slot_B": ["doceb909d6b9ee1_chunk000004", "doc6e7afe84fe31_chunk000004"], "slot_nuggets": {"slot_A": ["QFR is intended for visualization of X-ray angiographic images.", "QFR is intended for calculations in X-ray angiographic images of coronary vessel segments.", "QFR results are intended to support clinical decisions about diagnosis and treatment."], "slot_B": ["If QFR results are used for diagnosis or treatment guidance, they must be interpreted by a qualified medical professional."]}}
{"id": "q_009", "task": "evidencebased_qa", "question": "When is the Review screen of the QFR analysis shown, what can the user review there, and how can a brand-new QFR analysis be started from that screen?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000042"], "slot_B": ["doceb909d6b9ee1_chunk000044"], "slot_nuggets": {"slot_A": ["The Review screen is shown when a QFR analysis is closed.", "The Review screen is also shown when a QFR analysis is reloaded from the Studies page.", "The user can review the contours, lesions, and physiological and morphological results."], "slot_B": ["A new QFR analysis can be started from the Review screen.", "The start-new-analysis button loads all XA series of the active study.", "The new QFR analysis starts at the Vessel Selection screen."]}}
{"id": "q_010", "task": "evidencebased_qa", "question": "What is the difference between closing a study and logging off from QFR, and what does the user see after logging back on?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000045"], "slot_B": ["doc639a7e988eae_chunk000000"], "slot_nuggets": {"slot_A": ["Closing the study cancels the open QFR analysis.", "Logging off does not cancel an open QFR analysis.", "The analysis state is saved on the server and restored when the user logs on again."], "slot_B": ["The user logs on through a web browser using Windows user account credentials.", "By default, the STUDIES tab is shown after logon.", "The STUDIES tab shows patient studies with XA image series present in QFR."]}}
{"id": "q_011", "task": "evidencebased_qa", "question": "What does QFR automatically detect in the Contours step, and what warning can help the user check the reference diameter?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000030", "doceb909d6b9ee1_chunk000008", "doc639a7e988eae_chunk000005", "doc6e7afe84fe31_chunk000005"], "slot_B": ["doc639a7e988eae_chunk000012"], "slot_nuggets": {"slot_A": ["QFR automatically detects the start and end points of the target vessel.", "QFR automatically detects the pathline and vessel contours.", "The user can verify or correct these detections if needed."], "slot_B": ["The QFR App warns when reference diameter values are outside the normal healthy range.", "The user should check for contour abnormalities when this warning appears.", "The user should correct the contours if needed."]}}
{"id": "q_012", "task": "evidencebased_qa", "question": "What operator step was needed for Tu et al.'s real-time 3D QCA co-registration approach, and what was novel about the vessel segments evaluated in their validation study?", "required_slots": 2, "slot_A": ["docf8f69e70bd2a_chunk000007"], "slot_B": ["docf8f69e70bd2a_chunk000020", "docf8f69e70bd2a_chunk000021"], "slot_nuggets": {"slot_A": ["The approach only required the operator to reconstruct the arterial centerline from two angiographic images.", "This arterial centerline reconstruction is a standard step in 3D QCA."], "slot_B": ["The study evaluated non-stented vessel segments.", "The study applied 3D QCA to those non-stented vessel segments.", "Real-time co-registration was used to guarantee point-to-point correspondence between imaging modalities."]}}
{"id": "q_013", "task": "evidencebased_qa", "question": "In Tu et al.'s 2015 JACC bifurcation paper, what reclassification effect did the new bifurcation analysis produce compared with straight analysis, and what sample-size limitation did the authors acknowledge?", "required_slots": 2, "slot_A": ["doc7b681e429c95_chunk000014", "doc7b681e429c95_chunk000015"], "slot_B": ["doc7b681e429c95_chunk000022"], "slot_nuggets": {"slot_A": ["Bifurcation analysis reclassified the straight analysis in 19 lesions.", "Of these reclassifications, 16 were correct and 3 were incorrect."], "slot_B": ["The authors acknowledged that the study examined a limited sample size.", "They could not perform a meaningful ROC analysis for the cohort with FFR measurement in the side branch."]}}
{"id": "q_014", "task": "evidencebased_qa", "question": "After a single-vessel analysis is closed, how can the user still view detailed analysis results, and how does QAngio XA 3D detect corresponding vessel segments in the two XA acquisitions?", "required_slots": 2, "slot_A": ["doc6e7afe84fe31_chunk000028"], "slot_B": ["doc6e7afe84fe31_chunk000024"], "slot_nuggets": {"slot_A": ["After closing a single-vessel analysis, QAngio XA 3D can still show detailed information without editing the analysis.", "The user can show this information by selecting the View details checkbox.", "The 3D vessel reconstruction, diameter diagram, and QFR diagram are shown."], "slot_B": ["The detection of corresponding vessel segments between the two XA acquisitions was improved.", "The user places both proximal and distal vessel markers in one image first.", "QAngio XA 3D then automatically detects the corresponding proximal and distal markers in the second image."]}}
{"id": "q_015", "task": "evidencebased_qa", "question": "When does QFR ask the user to confirm the vessel segment of analysis, and what morphology information is shown in comparative mode in the Results step?", "required_slots": 2, "slot_A": ["doc639a7e988eae_chunk000007"], "slot_B": ["doc639a7e988eae_chunk000010"], "slot_nuggets": {"slot_A": ["QFR asks the user to confirm the vessel segment if the end point has been moved into another vessel segment.", "This can happen when the end point is repositioned into a major side branch.", "The correct vessel model is needed for accurate QFR calculation."], "slot_B": ["In the right viewport, morphology data includes MLD, Reference Diameter, and Lesion Length.", "Comparative mode shows morphology data for all lesions.", "The selected lesion is highlighted."]}}
{"id": "q_016", "task": "evidencebased_qa", "question": "Which Automatic Frame Count enhancement reduces the need for manual frame counting or fixed flow velocity, and what hardware-dependent defect was resolved in earlier QAngio XA 3D releases?", "required_slots": 2, "slot_A": ["doc6e7afe84fe31_chunk000009", "doc6e7afe84fe31_chunk000011"], "slot_B": ["doc6e7afe84fe31_chunk000013"], "slot_nuggets": {"slot_A": ["The Automatic Frame Count algorithm gives results in more cases.", "This reduces the need for manual frame count or fixed flow velocity."], "slot_B": ["Earlier QAngio XA 3D 2.1 releases could give small automatic frame count differences depending on computer hardware.", "These differences appeared as failures of the QFR Post Install Tests.", "The issue was resolved so automatic frame count results are consistent across computer systems."]}}
{"id": "q_017", "task": "evidencebased_qa", "question": "What technical criteria must DICOM XA image acquisitions meet to be valid input for a QFR analysis, and what does the QFR analysis workflow display in its image viewports?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000013"], "slot_B": ["doceb909d6b9ee1_chunk000021"], "slot_nuggets": {"slot_A": ["DICOM XA monoplane or biplane acquisitions can be used as input for QFR analysis.", "The images must have square pixels with a 1:1 pixel aspect ratio.", "The images must include isocenter calibration data, be grayscale and have at least five image frames."], "slot_B": ["The QFR analysis workflow steps have two image viewports that display the XA image data.", "Each viewport has a viewport control toolbar.", "Some viewports have textual overlays."]}}
{"id": "q_018", "task": "evidencebased_qa", "question": "In the Results step, what should the user verify before finishing the QFR analysis, and how is the analysis saved if the user later edits it?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000035", "doceb909d6b9ee1_chunk000008", "doc6e7afe84fe31_chunk000005"], "slot_B": ["doceb909d6b9ee1_chunk000043"], "slot_nuggets": {"slot_A": ["The user should verify Delta QFR, Residual QFR, and Diameter Stenosis %.", "The user should verify Minimal Lumen Diameter, Reference Diameter, and Lesion Length.", "The user should verify detected lesions and correct them if needed."], "slot_B": ["The user can edit a QFR analysis to correct contours or lesions.", "After editing and finishing, the modified analysis is saved as a new analysis.", "The old analysis is not overwritten."]}}
{"id": "q_019", "task": "evidencebased_qa", "question": "Once a QFR analysis has been completed for a study, how can a user reopen and review or edit it, and how is a previous QFR analysis or study removed from the lists?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000019"], "slot_B": ["doceb909d6b9ee1_chunk000020"], "slot_nuggets": {"slot_A": ["Selecting a study from the Studies list shows earlier QFR analyses for that study.", "A previous QFR analysis can be reopened, reviewed, and edited."], "slot_B": ["A study can be removed by right-clicking the study entry and selecting Delete Study.", "A QFR analysis can be removed by right-clicking the analysis entry and selecting Delete QFR analysis."]}}
{"id": "q_020", "task": "evidencebased_qa", "question": "On entering the Vessel Selection step, how does QFR handle ED-frame selection, and which coronary vessel types does it classify XA series into?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000024", "doceb909d6b9ee1_chunk000027", "doc639a7e988eae_chunk000004"], "slot_B": ["doceb909d6b9ee1_chunk000025", "doc639a7e988eae_chunk000001"], "slot_nuggets": {"slot_A": ["QFR automatically detects ED phases of the heart cycle.", "QFR automatically selects an optimal ED frame for analysis.", "The user should verify the ED frame selection and change it if needed."], "slot_B": ["QFR uses AI to classify visible and suitable coronary vessels in each XA series.", "The vessel types are Left Anterior Descending (LAD), Left Circumflex (LCX), and Right Coronary Artery (RCA).", "Series with the same detected vessel type are grouped together on a tab, and the ALL tab shows suitable series across vessel types."]}}
{"id": "q_021", "task": "evidencebased_qa", "question": "In the QFR Studies list, how can a user filter the listed studies, how can the user sort them, and how is a new QFR analysis started from a selected study?", "required_slots": 3, "slot_A": ["doceb909d6b9ee1_chunk000018"], "slot_B": ["doceb909d6b9ee1_chunk000019"], "slot_C": ["doceb909d6b9ee1_chunk000020"], "slot_nuggets": {"slot_A": ["The user can activate the filter control.", "The user can select the column to filter on.", "The user can enter a filter value to find matching studies."], "slot_B": ["The user can hover over a column header to show the sort icon.", "Clicking the sort icon sorts the Studies list ascending.", "Clicking the sort icon again sorts the Studies list descending."], "slot_C": ["A new QFR analysis can be started by double-clicking a study entry.", "A new QFR analysis can be started by right-clicking a study entry and selecting New QFR Analysis.", "A new QFR analysis can be started by clicking the New QFR Analysis icon from the analysis list."]}}
{"id": "q_022", "task": "evidencebased_qa", "question": "What are the minimal hardware requirements for a QFR client machine, and which web browsers with version numbers are supported to run QFR?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000010"], "slot_B": ["doceb909d6b9ee1_chunk000011"], "slot_nuggets": {"slot_A": ["QFR client machines require a 64-bit processor with 4 cores.", "QFR client machines require 8 GB RAM.", "QFR client machines require a network speed of at least 100 Mb/s and latency of at most 50 ms."], "slot_B": ["QFR supports Microsoft Edge version 116 or newer.", "QFR supports Google Chrome version 116 or newer."]}}
{"id": "q_023", "task": "evidencebased_qa", "question": "In the Results step, how do you adjust the proximal and distal boundaries of a detected lesion, and what does the white Index Marker show in the QFR diagram?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000040"], "slot_B": ["doceb909d6b9ee1_chunk000037"], "slot_nuggets": {"slot_A": ["Adjust a detected lesion by dragging its proximal or distal markers.", "The lesion markers can be dragged in the angiogram viewports, QFR diagram, or Diameter diagram.", "The lesion results update automatically after marker adjustment."], "slot_B": ["The white Index Marker is shown in the QFR diagram.", "The QFR and d(QFR)/ds values at the Index Marker are displayed at the top of the marker.", "The user can select and drag the Index Marker across the target vessel."]}}
{"id": "q_024", "task": "evidencebased_qa", "question": "How does the QFR software automatically detect the End-Diastolic image frame to use for the analysis, and what manual technique can the operator use to verify that a chosen frame is in the ED phase?", "required_slots": 2, "slot_A": ["doc639a7e988eae_chunk000004", "doceb909d6b9ee1_chunk000027"], "slot_B": ["doceb909d6b9ee1_chunk000029"], "slot_nuggets": {"slot_A": ["QFR automatically detects ED-phase image frames using ECG data or image data.", "QFR automatically selects the optimal ED frame as input for the analysis."], "slot_B": ["To verify the ED frame manually for left and right coronary arteries, find the image frame where the aortic valve opens and accumulated contrast flushes into the aorta, then go 2 or 3 frames backwards.", "For right coronary analysis, another way to find the ED frame is to look for the moment when the angles formed by the posterior descending and posterolateral arteries widen."]}}
{"id": "q_025", "task": "evidencebased_qa", "question": "During QFR image acquisition, what patient-handling instructions should the operator follow, and what should the operator aim for in terms of target-vessel opacification?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000015"], "slot_B": ["doceb909d6b9ee1_chunk000014"], "slot_nuggets": {"slot_A": ["Avoid moving the table early after contrast injection during the acquisition.", "Ask the patient to hold their breath if possible during the acquisition."], "slot_B": ["Aim for three full cardiac cycles.", "The target vessel should be fully opacified."]}}
{"id": "q_026", "task": "evidencebased_qa", "question": "What technical image or acquisition conditions make QFR measurements unreliable, and which patient cardiovascular conditions exclude QFR from being applied?", "required_slots": 2, "slot_A": ["doc6e7afe84fe31_chunk000004", "doceb909d6b9ee1_chunk000004"], "slot_B": ["doc6e7afe84fe31_chunk000003", "doceb909d6b9ee1_chunk000003"], "slot_nuggets": {"slot_A": ["QFR cannot be performed accurately when there is too much overlap of other vessels with the lesion area in one or both acquisitions.", "QFR cannot be performed accurately when there is too much foreshortening of the target coronary artery in one or both acquisitions.", "QFR cannot be performed accurately when no nitroglycerin has been administered.", "QFR cannot be performed accurately in vessels with retrograde filling."], "slot_B": ["QFR should not be applied in patients with tachycardia above 100 bpm.", "QFR should not be applied in patients with systolic aortic resting blood pressure below 75 mm Hg.", "QFR should not be applied in patients with atrial fibrillation."]}}
{"id": "q_027", "task": "evidencebased_qa", "question": "How should the two QFR projections be chosen to assess plaque eccentricity, and what minimum frame rate should be used during acquisition?", "required_slots": 2, "slot_A": ["doc639a7e988eae_chunk000003"], "slot_B": ["doceb909d6b9ee1_chunk000014"], "slot_nuggets": {"slot_A": ["The projections should be as perpendicular as possible to the target vessel.", "The user should rotate around the target vessel."], "slot_B": ["Use a frame rate of at least 12.5 frames per second."]}}
{"id": "q_028", "task": "evidencebased_qa", "question": "In the 2012 validation study, what statistical methods were used to compare 3D QCA with IVUS or OCT, and what overall directional bias did the co-registered comparison reveal?", "required_slots": 2, "slot_A": ["docf8f69e70bd2a_chunk000010"], "slot_B": ["docf8f69e70bd2a_chunk000001", "docf8f69e70bd2a_chunk000024"], "slot_nuggets": {"slot_A": ["3D QCA was compared with IVUS or OCT using a paired t-test.", "Differences were evaluated with Bland-Altman plots.", "Correlations were assessed with Pearson's correlation coefficient."], "slot_B": ["The comparison suggested a bias toward larger lumen dimensions by IVUS and OCT.", "The bias was more pronounced in larger and tortuous vessels."]}}
{"id": "q_029", "task": "evidencebased_qa", "question": "If an XA series does not appear as a thumbnail under the LAD, LCX, or RCA vessel tabs, what should you check about the acquisition itself, and where might a still-usable but unclassified series still appear?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000013"], "slot_B": ["doceb909d6b9ee1_chunk000025"], "slot_nuggets": {"slot_A": ["QFR accepts DICOM XA monoplane or biplane acquisitions only if they meet the input criteria.", "The images should be grayscale.", "The images must have square pixels, isocenter calibration data, fixed angulations, and at least five frames.", "Acquisitions that fail these criteria are automatically excluded and are not visible as thumbnails in Vessel Selection."], "slot_B": ["QFR groups suitable XA series by detected vessel type: LAD, LCX, or RCA.", "Not all suitable XA series may be classified as LAD, LCX, or RCA.", "The ALL tab shows all XA series that are suitable as input, independent of the automatically detected vessel type."]}}
{"id": "q_030", "task": "evidencebased_qa", "question": "If a first attempt is likely to give a weak 3D reconstruction, what projection geometry should you plan, and what simple execution habits during acquisition reduce the chance of a bad run?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000014"], "slot_B": ["doceb909d6b9ee1_chunk000015"], "slot_nuggets": {"slot_A": ["QFR reconstruction requires two target-vessel acquisitions from different angles.", "The two acquisitions must be at least 25 degrees apart, with 35 to 50 degrees being optimal.", "The projections should be as perpendicular as possible to the target vessel.", "Before acquisition, check for severe overlap or foreshortening and rotate or angulate more if needed."], "slot_B": ["Avoid moving the table early after contrast injection during acquisition.", "Ask the patient to hold their breath if possible during acquisition.", "Make sure the entire target vessel is visible in both image projections."]}}
{"id": "q_031", "task": "evidencebased_qa", "question": "If you are searching a crowded Studies list for a specific patient text pattern or time window, how can you narrow the list first, and how do you then inspect older analyses for the matching study?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000018"], "slot_B": ["doceb909d6b9ee1_chunk000019"], "slot_nuggets": {"slot_A": ["The user can activate the filter control, choose a column, and enter a filter value.", "QFR supports filtering on text fields and on date values or date ranges."], "slot_B": ["Selecting a study shows earlier analyses for that study in the QFR analysis list.", "Those analyses can be reopened, reviewed, and edited."]}}
{"id": "q_032", "task": "evidencebased_qa", "question": "If a case involves left-main/LAD disease or the circumflex ostium, what QFR analysis limitations or strategy should the user consider, and which default projection pairs are recommended for LM+LAD/LCX and LCX/OM?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000034"], "slot_B": ["doceb909d6b9ee1_chunk000015"], "slot_nuggets": {"slot_A": ["Ostial LM or RCA stenosis currently excludes the use of QFR because it is a software limitation.", "If there are stenoses in both LM and LAD, the proximal point should be placed proximal to the stenosis in the LM.", "LM/LAD and circumflex disease should be analyzed separately because the vessel types have different physiological flow patterns.", "The LCX ostium can be difficult to assess because two optimal projections are required."], "slot_B": ["For LM + LAD/LCX, the recommended default projection pair is RAO 20, CAU 25 and AP, CAU 10.", "For LCX/OM, the recommended default projection pair is LAO 10, CAU 25 and RAO 25, CAU 25."]}}
{"id": "q_033", "task": "evidencebased_qa", "question": "How did corresponding-vessel-segment handling change from the marker-placement workflow to the later fully automated correspondence workflow?", "required_slots": 2, "slot_A": ["doc6e7afe84fe31_chunk000024"], "slot_B": ["doc6e7afe84fe31_chunk000012"], "slot_nuggets": {"slot_A": ["The user had to place both proximal and distal vessel markers in one image first.", "QAngio XA 3D then automatically detected the corresponding proximal and distal markers in the second image.", "After this automatic detection, manual corrections in one image no longer changed the vessel-marker locations in the second image."], "slot_B": ["Correspondence between the two angiograms is corrected completely automatically in the background.", "Manual correspondence corrections are no longer needed.", "The Correspondence step was removed from the analysis workflow."]}}
{"id": "q_034", "task": "evidencebased_qa", "question": "What happens if automatic segment detection creates a reversed vessel segment, and how does the one-time corresponding-marker detection explain why later manual corrections are treated differently?", "required_slots": 2, "slot_A": ["doc6e7afe84fe31_chunk000023"], "slot_B": ["doc6e7afe84fe31_chunk000024"], "slot_nuggets": {"slot_A": ["Automatic detection could create a reversed segment where proximal and distal segment markers were swapped in one XA acquisition.", "If the reversed segment is caused by automatic segment detection, QAngio XA 3D corrects it automatically.", "If the reversed segment is caused by manual corrections, no automatic correction occurs and the warning remains displayed."], "slot_B": ["Corresponding proximal and distal vessel markers are automatically detected in the second image after both markers are placed in one image.", "This automatic detection is executed only once.", "Manual corrections made afterwards in one image no longer change the vessel-marker locations in the second image."]}}
{"id": "q_035", "task": "evidencebased_qa", "question": "How did defining reference contours change from abnormal-part flagging to normal-area indication, and what warning is shown when reference contours taper incorrectly?", "required_slots": 2, "slot_A": ["doc6e7afe84fe31_chunk000027"], "slot_B": ["doc6e7afe84fe31_chunk000025"], "slot_nuggets": {"slot_A": ["Flagging abnormal vessel parts was replaced by indicating normal areas in the vessel.", "Normal areas are used to define the reference contours.", "Indicating normal areas is easier and faster than flagging.", "A fixed reference diameter can also be set at the proximal end of the vessel."], "slot_B": ["Reference contours normally decrease in diameter from the proximal to the distal vessel segment.", "QAngio XA 3D displays a warning when reference contours taper in the wrong direction."]}}
{"id": "q_036", "task": "evidencebased_qa", "question": "How did bifurcation-specific analysis perform compared with straight analysis, and what physiological explanation did the authors give for why bifurcation anatomy can affect FFR?", "required_slots": 2, "slot_A": ["doc7b681e429c95_chunk000014"], "slot_B": ["doc7b681e429c95_chunk000019", "doc7b681e429c95_chunk000020"], "slot_nuggets": {"slot_A": ["All bifurcation models were superior to conventional straight diameter-stenosis analysis for diagnosing FFR of 0.80 or lower.", "Straight analysis had a lower AUC than the bifurcation analyses."], "slot_B": ["In bifurcations, hyperemic flow can be redistributed toward the unobstructed branch.", "This can produce a higher FFR in the obstructed branch than the same stenosis geometry would have in a theoretical straight vessel."]}}
{"id": "q_037", "task": "evidencebased_qa", "question": "How does the new quantitative bifurcation model define the bifurcation structure, and what can happen to the diameter-stenosis function when crossing the carina?", "required_slots": 2, "slot_A": ["doc7b681e429c95_chunk000005"], "slot_B": ["doc7b681e429c95_chunk000006"], "slot_nuggets": {"slot_A": ["The model divides a bifurcation into the proximal main vessel, distal main vessel, and side branch.", "These vessel parts are connected by the bifurcation core.", "The distal main vessel and side branch merge into the proximal main vessel."], "slot_B": ["The stenosis function is split at the carina.", "Separate stenosis functions are used for the distal main vessel and side branch.", "The diameter-stenosis value can jump when crossing the carina."]}}
{"id": "q_038", "task": "evidencebased_qa", "question": "When entering the Results step, what does QFR first calculate before lesion/QFR results are determined, and which values should the user verify before clicking Finish?", "required_slots": 2, "slot_A": ["doc639a7e988eae_chunk000007"], "slot_B": ["doceb909d6b9ee1_chunk000035"], "slot_nuggets": {"slot_A": ["QFR first calculates the references.", "QFR first calculates the 3D vessel model.", "With these, QFR can detect lesions and calculate the vessel QFR result."], "slot_B": ["The user should verify Delta QFR, Residual QFR, and Diameter Stenosis %.", "The user should verify Minimal Lumen Diameter, Reference Diameter, and Lesion Length.", "The user should verify detected lesions and correct lesion markers if needed before clicking Finish."]}}
{"id": "q_039", "task": "evidencebased_qa", "question": "During coronary angiography, what should be checked before contrast injection, and how do TIMI flow grade and myocardial perfusion grade describe different aspects of angiographic result quality?", "required_slots": 3, "slot_A": ["doccb0fce7c3072_chunk000005"], "slot_B": ["doccb0fce7c3072_chunk000008"], "slot_C": ["doccb0fce7c3072_chunk000009"], "slot_nuggets": {"slot_A": ["The system should be flushed before engaging the coronary artery.", "The pressure waveform should be assessed.", "Contrast should not be injected until normal pressure is confirmed."], "slot_B": ["TIMI 0 means no antegrade flow beyond the coronary occlusion.", "TIMI 2 means delayed or sluggish antegrade flow with complete distal filling.", "TIMI 3 means normal flow with complete distal filling."], "slot_C": ["Myocardial perfusion grade 0 means minimal or no myocardial blush.", "Myocardial perfusion grade 2 means delayed entry and exit of dye from the microvasculature.", "Myocardial perfusion grade 3 means normal entry and exit of dye from the microvasculature."]}}
{"id": "q_040", "task": "evidencebased_qa", "question": "What do the QFR image viewports show, and how are mouse modes controlled across the viewports?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000021"], "slot_B": ["doceb909d6b9ee1_chunk000022"], "slot_nuggets": {"slot_A": ["The QFR analysis workflow has two image viewports that display XA image data.", "Each viewport has a viewport control toolbar.", "Some viewports include textual overlays."], "slot_B": ["Mouse mode is set with the viewport toolbar buttons.", "Mouse modes are synchronized across viewports.", "The scroll wheel scrolls through cine frames."]}}
{"id": "q_041", "task": "evidencebased_qa", "question": "How can the user reset a QFR viewport or temporarily hide the graphics overlay, and in which workflow steps are these controls used?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000023"], "slot_B": ["doceb909d6b9ee1_chunk000021"], "slot_nuggets": {"slot_A": ["The reset action returns the viewport to default zoom, pan, and window width or level values.", "Resetting the viewport also reactivates the analysis frame.", "The graphics overlay is hidden while the overlay-hiding button is pressed."], "slot_B": ["The image-viewing functions are available in the QFR analysis workflow steps.", "The QFR workflow steps are Vessel Selection, Contours, and Results."]}}
{"id": "q_042", "task": "evidencebased_qa", "question": "When interpreting angiographic projection names, what general rule determines RAO/LAO view naming, and how are AP, cranial, and caudal image-intensifier positions defined?", "required_slots": 2, "slot_A": ["docc2a440c5f1cd_chunk000001"], "slot_B": ["docc2a440c5f1cd_chunk000006"], "slot_nuggets": {"slot_A": ["The view is named by the body surface that faces the image intensifier or flat panel.", "Moving the image intensifier toward the patient's left side gives an LAO view.", "Moving the image intensifier toward the patient's right side gives an RAO view."], "slot_B": ["In AP position, the image intensifier is directly over the patient.", "Cranial means the image intensifier is tilted toward the patient's head.", "Caudal means the image intensifier is tilted toward the patient's feet."]}}
{"id": "q_043", "task": "evidencebased_qa", "question": "How does the cardiac silhouette change between LAO and RAO views, and how do the LAD and circumflex change their relative positions when moving from LAO to RAO?", "required_slots": 2, "slot_A": ["docc2a440c5f1cd_chunk000002"], "slot_B": ["docc2a440c5f1cd_chunk000009"], "slot_nuggets": {"slot_A": ["In LAO projection, the heart appears shorter and rounder.", "In RAO projection, the heart appears longer.", "In RAO projection, the tip extends toward the left chest wall."], "slot_B": ["In LAO projection, the LAD and circumflex are on opposite sides.", "When rotating to RAO, the LAD changes to the left side.", "When rotating to RAO, the circumflex moves toward the middle or more rightward position."]}}
{"id": "q_044", "task": "evidencebased_qa", "question": "When choosing left-coronary views, what do LAO cranial and LAO caudal angulation show, and how do cranial versus caudal views help visualize the LAD, diagonals, circumflex, and left main?", "required_slots": 2, "slot_A": ["docc2a440c5f1cd_chunk000008"], "slot_B": ["docc2a440c5f1cd_chunk000010"], "slot_nuggets": {"slot_A": ["LAO cranial angulation exaggerates the left main segment.", "LAO caudal angulation views the coronary arteries from underneath.", "LAO caudal angulation produces the spider view."], "slot_B": ["In RAO cranial angulation, the circumflex is tipped upward, foreshortened, and overlapped with the LAD.", "Cranial views are best used to see the LAD and diagonals.", "Caudal views are best used to see the circumflex and left main segments."]}}
{"id": "q_045", "task": "evidencebased_qa", "question": "In the QFR viewport, how can the user change the active image frame, and how are mouse modes shared across viewports?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000028"], "slot_B": ["doceb909d6b9ee1_chunk000022"], "slot_nuggets": {"slot_A": ["The active image frame can be changed with the frame selection control, PREV/NEXT buttons, or keyboard arrows."], "slot_B": ["Mouse modes are synchronized across viewports.", "The right mouse button controls window width/level and the middle mouse button controls zooming."]}}
{"id": "q_046", "task": "evidencebased_qa", "question": "When placing the proximal and distal vessel points in the Contours step, what anatomical rules must the user follow, and what special software limitation applies to ostial left main or RCA stenoses?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000033"], "slot_B": ["doceb909d6b9ee1_chunk000034"], "slot_nuggets": {"slot_A": ["The proximal and distal points should match the same anatomical locations in both views.", "The proximal point should be placed at the vessel ostium.", "The distal point should be placed distally enough to include the diseased vessel segment."], "slot_B": ["Ostial left main or RCA stenosis excludes QFR use because of a software limitation.", "If both the left main and LAD have stenoses, the proximal point should be placed proximal to the left main stenosis."]}}
{"id": "q_047", "task": "evidencebased_qa", "question": "What server-client architecture does QFR use, and what security and authentication measures govern access?", "required_slots": 2, "slot_A": ["doc6e7afe84fe31_chunk000006", "doceb909d6b9ee1_chunk000011"], "slot_B": ["doceb909d6b9ee1_chunk000012"], "slot_nuggets": {"slot_A": ["QFR runs on a server machine instead of needing installation on each workstation.", "Client workstations can access QFR over the network through a web browser.", "Supported browsers include Microsoft Edge and Google Chrome."], "slot_B": ["Users log on to QFR using their Windows username and password.", "Only authorized users are allowed to access QFR.", "Users who are not authorized must contact their system administrator to request access."]}}
{"id": "q_048", "task": "evidencebased_qa", "question": "In the QFR Results step, how does the user enable or disable a detected lesion, and what happens when the analysis is completed?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000040"], "slot_B": ["doceb909d6b9ee1_chunk000041"], "slot_nuggets": {"slot_A": ["An enabled lesion is visible on the angiogram, diagrams, and report.", "A disabled lesion is hidden from the angiograms, diagrams, and report."], "slot_B": ["After verifying the lesions, the user clicks Finish to complete the QFR analysis.", "Completing the analysis automatically saves the QFR analysis and report.", "The QFR analysis and report are archived to PACS if configured."]}}
{"id": "q_049", "task": "evidencebased_qa", "question": "What information is included in the QFR report, and what does the User Manual say happens when the QFR analysis is completed?", "required_slots": 2, "slot_A": ["doc639a7e988eae_chunk000013", "doceb909d6b9ee1_chunk000043"], "slot_B": ["doceb909d6b9ee1_chunk000041"], "slot_nuggets": {"slot_A": ["The QFR report is a one-page report.", "The report includes patient details, study details, and QFR results.", "The report includes screenshots of the angiograms, QFR diagram, and diameter diagram.", "The report can be downloaded as a PDF."], "slot_B": ["Completing the analysis automatically saves the QFR analysis and report.", "The QFR analysis and report are archived to PACS if configured."]}}
{"id": "q_050", "task": "evidencebased_qa", "question": "Who may use QFR, who must interpret the results when they are used for diagnosis or treatment guidance, and what clinical decisions do QFR analysis results support?", "required_slots": 2, "slot_A": ["doceb909d6b9ee1_chunk000004", "doc6e7afe84fe31_chunk000004"], "slot_B": ["doceb909d6b9ee1_chunk000002", "doc6e7afe84fe31_chunk000002"], "slot_nuggets": {"slot_A": ["QFR must be used by cardiologists, trained technicians, or trained nurses.", "QFR must be interpreted by a qualified medical professional."], "slot_B": ["QFR results support clinical decision-making about diagnosis and possible treatment options for coronary vessels.", "QFR results support evaluation of interventions or drug therapy for coronary vessel conditions."]}}